![pasted-graphic.jpg](files/pasted-graphic.jpg.png)
![integrin-activation-network.jpg](files/integrin-activation-network.jpg.png)
![the-rho_rap-module-of-integrin-regulation.jpg](files/the-rho_rap-module-of-integrin-regulation.jpg.png)
RED nodes = pro-adhesive role
BLUE nodes = anti-adhesive role
GREEN nodes = hypothetic role
See the updated list (09/01/2015) of signaling proteins involved in the regulation of rapid integrin activation (HGNC protein IDs).
Not all listed proteins respect the “four criteria” for integrin affinity triggering described in Front Immunol. 2012;3:127.
From Front Immunol. 2012;3:127
![fimmu-03-00127-t001](files/fimmu-03-00127-t001.jpg)