Plasmacytoid Dendritic Cell, Slan+-Monocyte and Natural Killer Cell Counts Function as Blood Cell-Based Biomarkers for Predicting Responses to Immune Checkpoint Inhibitor Monotherapy in Non-Small Cell Lung Cancer Patients.
Pettinella F, Lattanzi C, Donini M, Caveggion E, Marini O, Iannoto G, Costa S, Zenaro E, Moderno Fortunato T, Gasperini S, Giani M,
Belluomini L, Sposito M, Insolda J, Scaglione IM, Milella M, Adamo A, Poffe O, Bronte V, Dusi S, Cassatella MA, Ugel S, Pilotto S and Scapini S.
Cancers 2023, 15, 5285. https://doi.org/10.3390/cancers15215285
An isoform of the giant protein titin is a master regulator of human T lymphocyte trafficking.
Toffali L, D’Ulivo B, Giagulli C, Montresor A, Zenaro E, Delledonne M, Rossato M, Iadarola B, Sbarbati A, Bernardi P, Angelini G, Rossi B, Lopez N, Linke WA, Unger A, Di Silvestre D, Benazzi L, De Palma A, Motta S, Constantin G, Mauri P, and Laudanna C.
Cell Reports. 2023 May 18; 42(5):112516. https://doi.org/10.1016/j.celrep.2023.112516.
Alpha4 beta7 integrin controls Th17 cell trafficking in the spinal cord leptomeninges during experimental autoimmune encephalomyelitis.
Rossi B, Dusi S, Angelini G, Bani A, Lopez N, Della Bianca V, Pietronigro EC, Zenaro E, Zocco C and Constantin G.
Front Immunol. 2023 Apr 18;14:1553.
https://doi.org/10.3389/fimmu.2023.1071553
Systemic inflammation causes microglial dysfunction associated with a vascular AD phenotype.
Bathini P, Dupanloup I, Zenaro E, Terrabuio E, Fischer A, Babaliani E, Doucey MA, Alberi L.
Brain, Behavior, & Immunity. Volume 28, March 2023, 100568.
https://doi.org/10.1016/j.bbih.2022.100568
Neutrophils inhibit γδ T cell functions in the imiquimod-induced mouse model of psoriasis.
Costa S, Bevilacqua D, Caveggion E, Gasperini S, Zenaro E, Donini M, Dusi S, Pettinella F, Constantin G, Lonardi S, Vermi W, De Sanctis F, Ugel S, Cestari T, Abram C, Lowell CA, Rodegher A, Tagliaro F, Girolomoni G, Cassatella MA, Scapini P.
Frontiers in Immunology. 2022 November, 15. doi:10.3389/fimmu.2022.1049079.
The role of neutrophils in the dysfunction of central nervous system barriers.
Santos-Lima B., Pietronigro EC, Terrabuio E, Zenaro E#, and Constantin G#.
Frontiers in Aging Neuroscience. 2022 August, 14;1663-4365. Review
Editorial: Neurodegenerative Diseases: Looking Beyond the Boundaries of the Brain.
Gutiérrez-Ospina g, Perez-Cruz C, Zenaro E and Zille M.
Frontiers in Neuroscience. 2022 June, 23. doi: 10.3389/fnins.2022.929786. PMID: 35812215
In vitro models of neurodegenerative diseases.
Slanzi A, Iannoto G, Rossi B, Zenaro E, Constantin G.
Front. Cell Dev. Biol., 13 May 2020. doi.org/10.3389/fcell.2020.00328. Review.
Role of neutrophils in neurodegenerative diseases.
Rossi B, Constantin G, Zenaro E.
IImmunobiology. 2019 Nov 9. doi: 10.1016/j.imbio.2019.10.014. Review.
PMID: 31740077
LFA-1 Controls Th1 and Th17 Motility Behavior in the Inflamed Central Nervous System.
Dusi S, Angiari S, Pietronigro EC, Lopez N, Angelini G, Zenaro E, Della Bianca V,
Tosadori G, Paris F, Amoruso A, Carlucci T, Constantin G, Rossi B.
Front Immunol. 2019 Oct 18;10:2436. doi: 10.3389/fimmu.2019.02436
PMID: 31681316
Blockade of α4 integrins reduces leukocyte–endothelial interactions in cerebral
vessels and improves memory in a mouse model of Alzheimer’s disease
Pietronigro EC*, Zenaro E*, Della Bianca V, Dusi S, Terrabuio E, Iannoto G, Slanzi A,
Ghasemi S, Nagarajan R, Piacentino G, Tosadori G, Rossi B, Constantin G.
Sci Rep. 2019 Aug 19;9(1):12055. doi: 10.1038/s41598-019-48538-x.
PMID: 31427644
NETosis in Alzheimer's Disease.
Pietronigro EC, Della Bianca V, Zenaro E, Constantin G.
Front Immunol. 2017 Mar 2;8:211. doi: 10.3389/fimmu.2017.00211. eCollection 2017. Review.
PMID: 28303140
Targeting neuroinflammation in the treatment and prevention of Alzheimer's disease.
Zenaro E, Constantin G.
Drugs of the Future 42(1):21. January 2017. doi: 10.1358/dof.2017.042.01.2564104. Review.
The blood-brain barrier in Alzheimer's disease.
Zenaro E, Piacentino G, Constantin G.
Neurobiol Dis. 2017 Nov;107:41-56. doi: 10.1016/j.nbd.2016.07.007. Epub 2016 Jul 15. Review.
PMID: 27425887
Imaging of Leukocyte Trafficking in Alzheimer's Disease.
Pietronigro E, Zenaro E, Constantin G.
Front Immunol. 2016 Feb 15;7:33. doi: 10.3389/fimmu.2016.00033. eCollection 2016. Review.
PMID: 26913031
Neutrophils promote Alzheimer's disease-like pathology and cognitive decline via LFA-1 integrin.
Zenaro E, Pietronigro E, Della Bianca V, Piacentino G, Marongiu L, Budui S, Turano E, Rossi B, Angiari S, Dusi S, Montresor A, Carlucci T, Nanì S, Tosadori G, Calciano L, Catalucci D, Berton G, Bonetti B, Constantin G.
Nat Med. 2015 Aug;21(8):880-6. doi: 10.1038/nm.3913. Epub 2015 Jul 27.
PMID: 26214837
TIM-1 glycoprotein binds the adhesion receptor P-selectin and mediates T cell trafficking during inflammation and autoimmunity.
Angiari S, Donnarumma T, Rossi B, Dusi S, Pietronigro E, Zenaro E, Della Bianca V, Toffali L, Piacentino G, Budui S, Rennert P, Xiao S, Laudanna C, Casasnovas JM, Kuchroo VK, Constantin G.
Immunity. 2014 Apr 17;40(4):542-53. doi: 10.1016/j.immuni.2014.03.004. Epub 2014 Apr 3.
PMID: 24703780
Regulatory T cells suppress the late phase of the immune response in lymph nodes through P-selectin glycoprotein ligand-1.
Angiari S, Rossi B, Piccio L, Zinselmeyer BH, Budui S, Zenaro E, Della Bianca V, Bach SD, Scarpini E, Bolomini-Vittori M, Piacentino G, Dusi S, Laudanna C, Cross AH, Miller MJ, Constantin G.
J Immunol. 2013 Dec 1;191(11):5489-500. doi: 10.4049/jimmunol.1301235. Epub 2013 Oct 30.
PMID: 24174617
ESAT-6 and HspX improve the effectiveness of BCG to induce human dendritic cells-dependent Th1 and NK cells activation.
Marongiu L, Donini M, Toffali L, Zenaro E, Dusi S.
PLoS One. 2013 Oct 9;8(10):e75684. doi: 10.1371/journal.pone.0075684. eCollection 2013.
PMID: 24130733
Use of imaging to study leukocyte trafficking in the central nervous system.
Zenaro E, Rossi B, Angiari S, Constantin G.
Immunol Cell Biol. 2013 Apr;91(4):271-80. doi: 10.1038/icb.2012.81. Epub 2013 Jan 22. Review.
PMID: 23337699
Burkholderia fungorum DBT1: a promising bacterial strain for bioremediation of PAHs-contaminated soils.
Andreolli M, Lampis S, Zenaro E, Salkinoja-Salonen M, Vallini G.
FEMS Microbiol Lett. 2011 Jun;319(1):11-8. doi: 10.1111/j.1574-6968.2011.02259.x. Epub 2011 Mar 31.
PMID: 21388438
Inverse agonism of cannabinoid CB1 receptor blocks the adhesion of encephalitogenic T cells in inflamed brain venules by a protein kinase A-dependent mechanism.
Rossi B, Zenaro E, Angiari S, Ottoboni L, Bach S, Piccio L, Pietronigro EC, Scarpini E, Fusco M, Leon A, Constantin G.
J Neuroimmunol. 2011 Apr;233(1-2):97-105. doi: 10.1016/j.jneuroim.2010.12.005. Epub 2011 Jan 7.
PMID: 21216016
Vascular inflammation in central nervous system diseases: adhesion receptors controlling leukocyte-endothelial interactions.
Rossi B, Angiari S, Zenaro E, Budui SL, Constantin G.
J Leukoc Biol. 2011 Apr;89(4):539-56. doi: 10.1189/jlb.0710432. Epub 2010 Dec 17. Review.
PMID: 21169520
Regulation of leukocyte recruitment by the long pentraxin PTX3.
Deban L, Russo RC, Sironi M, Moalli F, Scanziani M, Zambelli V, Cuccovillo I, Bastone A, Gobbi M, Valentino S, Doni A, Garlanda C, Danese S, Salvatori G, Sassano M, Evangelista V, Rossi B, Zenaro E, Constantin G, Laudanna C, Bottazzi B, Mantovani A.
Nat Immunol. 2010 Apr;11(4):328-34. doi: 10.1038/ni.1854. Epub 2010 Mar 7.
PMID: 20208538
Induction of Th1/Th17 immune response by Mycobacterium tuberculosis: role of dectin-1, Mannose Receptor, and DC-SIGN.
Zenaro E, Donini M, Dusi S.
J Leukoc Biol. 2009 Dec;86(6):1393-401. doi: 10.1189/jlb.0409242. Epub 2009 Sep 22.
PMID: 19773555
Mutant HbpR transcription activator isolation for 2-chlorobiphenyl via green fluorescent protein-based flow cytometry and cell sorting.
Beggah S, Vogne C, Zenaro E, Van Der Meer JR.
Microb Biotechnol. 2008 Jan;1(1):68-78. doi: 10.1111/j.1751-7915.2007.00008.x.
PMID: 21261823
NADPH oxidase of human dendritic cells: role in Candida albicans killing and regulation by interferons, dectin-1 and CD206.
Donini M*, Zenaro E*, Tamassia N, Dusi S.
Eur J Immunol. 2007 May;37(5):1194-203.
PMID: 17407098
G-CSF treatment of severe congenital neutropenia reverses neutropenia but does not correct the underlying functional deficiency of the neutrophil in defending against microorganisms.
Donini M, Fontana S, Savoldi G, Vermi W, Tassone L, Gentili F, Zenaro E, Ferrari D, Notarangelo LD, Porta F, Facchetti F, Notarangelo LD, Dusi S, Badolato R.
Blood. 2007 Jun 1;109(11):4716-23. Epub 2007 Feb 20.
PMID: 17311988