ID annotation.Assigned_by annotation.DB annotation.DB:Reference annotation.DB_Object_ID annotation.DB_Object_Name annotation.DB_Object_Type annotation.Date annotation.Evidence annotation.GO BIOLOGICAL_PROCESS annotation.GO CELLULAR_COMPONENT annotation.GO MOLECULAR_FUNCTION annotation.Qualifier annotation.Taxon annotation.With (or) From A1BG UniProtKB UniProtKB {GO:0008150=GO_REF:0000015, GO:0003674=GO_REF:0000015, GO:0005576=PMID:3458201} P04217 Alpha-1B-glycoprotein protein 20070222 {GO:0008150=ND, GO:0003674=ND, GO:0005576=IDA} biological_process extracellular region molecular_function Human A1CF HPA UniProtKB {GO:0006397=GO_REF:0000037, GO:0030895=PMID:10781591, GO:0005515=PMID:12896982, GO:0003725=PMID:11871661, GO:0010467=Reactome:REACT_71, GO:0003727=PMID:11871661, GO:0016556=Reactome:REACT_1757, GO:0005783=GO_REF:0000039, GO:0003723=PMID:10669759, GO:0016554=Reactome:REACT_167, GO:0050821=PMID:12881431, GO:0003676=GO_REF:0000002, GO:0005737=GO_REF:0000052, GO:0000166=GO_REF:0000002, GO:0005654=Reactome:REACT_1850} Q9NQ94 APOBEC1 complementation factor protein 20110516 {GO:0006397=IEA, GO:0030895=IDA, GO:0005515=IPI, GO:0003725=IDA, GO:0010467=TAS, GO:0003727=IDA, GO:0016556=TAS, GO:0005783=IEA, GO:0003723=TAS, GO:0016554=TAS, GO:0050821=IDA, GO:0003676=IEA, GO:0005737=IDA, GO:0000166=IEA, GO:0005654=TAS} cytidine to uridine editing, gene expression, mRNA modification, mRNA processing, protein stabilization apolipoprotein B mRNA editing enzyme complex, cytoplasm, endoplasmic reticulum, nucleoplasm RNA binding, double-stranded RNA binding, nucleic acid binding, nucleotide binding, protein binding, single-stranded RNA binding Human A2M Reactome UniProtKB {GO:0005515=PMID:14687906, GO:0051056=Reactome:REACT_11051, GO:0001869=PMID:12538697, GO:0004866=GO_REF:0000002, GO:0043120=PMID:9714181, GO:0007264=Reactome:REACT_11044, GO:0004867=PMID:12538697, GO:0030168=Reactome:REACT_798, GO:0005576=Reactome:REACT_21351, GO:0019959=PMID:10880251, GO:0005615=GO_REF:0000002, GO:0005829=Reactome:REACT_9982, GO:0048863=GO_REF:0000019, GO:0019966=PMID:9714181, GO:0019838=PMID:9398211, GO:0007596=Reactome:REACT_2051, GO:0007597=Reactome:REACT_326, GO:0002576=Reactome:REACT_318, GO:0031093=Reactome:REACT_21351, GO:0019899=PMID:11435418} P01023 Alpha-2-macroglobulin protein 20130301 {GO:0005515=IPI, GO:0051056=TAS, GO:0001869=IDA, GO:0004866=IEA, GO:0043120=IDA, GO:0007264=TAS, GO:0004867=IDA, GO:0030168=TAS, GO:0005576=TAS, GO:0019959=IPI, GO:0005615=IEA, GO:0005829=TAS, GO:0048863=IEA, GO:0019966=IDA, GO:0019838=IDA, GO:0007596=TAS, GO:0007597=TAS, GO:0002576=TAS, GO:0031093=TAS, GO:0019899=IPI} blood coagulation, blood coagulation, intrinsic pathway, negative regulation of complement activation, lectin pathway, platelet activation, platelet degranulation, regulation of small GTPase mediated signal transduction, small GTPase mediated signal transduction, stem cell differentiation cytosol, extracellular region, extracellular space, platelet alpha granule lumen endopeptidase inhibitor activity, enzyme binding, growth factor binding, interleukin-1 binding, interleukin-8 binding, protein binding, serine-type endopeptidase inhibitor activity, tumor necrosis factor binding Human A4GALT MGI UniProtKB {GO:0007009=PMID:10747952, GO:0030173=PMID:10748143, GO:0050512=GO_REF:0000003, GO:0016020=PMID:10748143, GO:0005795=GO_REF:0000002, GO:0006688=PMID:10748143, GO:0006486=GO_REF:0000041, GO:0008378=PMID:10748143} Q9NPC4 Lactosylceramide 4-alpha-galactosyltransferase protein 20120514 {GO:0007009=IDA, GO:0030173=NAS, GO:0050512=IEA, GO:0016020=IDA, GO:0005795=IEA, GO:0006688=NAS, GO:0006486=IEA, GO:0008378=IDA} glycosphingolipid biosynthetic process, plasma membrane organization, protein glycosylation Golgi stack, integral to Golgi membrane, membrane galactosyltransferase activity, lactosylceramide 4-alpha-galactosyltransferase activity Human AAAS HPA UniProtKB {GO:0022415=Reactome:REACT_6361, GO:0005813=GO_REF:0000052, GO:0031965=GO_REF:0000052, GO:0005975=Reactome:REACT_474, GO:0019221=Reactome:REACT_25229, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0044281=Reactome:REACT_111217, GO:0005635=Reactome:REACT_115827, GO:0055085=Reactome:REACT_19118, GO:0010827=Reactome:REACT_6804, GO:0008645=Reactome:REACT_9441, GO:0006913=PMID:12730363, GO:0009566=GO_REF:0000019, GO:0003674=GO_REF:0000015, GO:0005737=GO_REF:0000052, GO:0015758=Reactome:REACT_212, GO:0005643=PMID:12730363, GO:0016032=Reactome:REACT_6256, GO:0007612=GO_REF:0000019, GO:0046822=PMID:12730363} Q9NRG9 Aladin protein 20110516 {GO:0022415=TAS, GO:0005813=IDA, GO:0031965=IDA, GO:0005975=TAS, GO:0019221=TAS, GO:0005730=IDA, GO:0005634=IDA, GO:0044281=TAS, GO:0005635=TAS, GO:0055085=TAS, GO:0010827=TAS, GO:0008645=TAS, GO:0006913=IDA, GO:0009566=IEA, GO:0003674=ND, GO:0005737=IDA, GO:0015758=TAS, GO:0005643=IDA, GO:0016032=TAS, GO:0007612=IEA, GO:0046822=NAS} carbohydrate metabolic process, cytokine-mediated signaling pathway, fertilization, glucose transport, hexose transport, learning, nucleocytoplasmic transport, regulation of glucose transport, regulation of nucleocytoplasmic transport, small molecule metabolic process, transmembrane transport, viral reproduction, viral reproductive process centrosome, cytoplasm, nuclear envelope, nuclear membrane, nuclear pore, nucleolus, nucleus molecular_function Human AACS UniProtKB UniProtKB {GO:0007584=GO_REF:0000019, GO:0042493=GO_REF:0000019, GO:0045471=GO_REF:0000019, GO:0034201=GO_REF:0000019, GO:0003824=GO_REF:0000002, GO:0005524=GO_REF:0000037, GO:0014074=GO_REF:0000019, GO:0047760=GO_REF:0000019, GO:0005829=GO_REF:0000039, GO:0001889=GO_REF:0000019, GO:0071397=GO_REF:0000019, GO:0042594=GO_REF:0000019, GO:0071394=GO_REF:0000019, GO:0050872=GO_REF:0000019, GO:0006631=GO_REF:0000037, GO:0032024=GO_REF:0000019, GO:0071333=GO_REF:0000019, GO:0060612=GO_REF:0000019, GO:0030729=GO_REF:0000003} Q86V21 Acetoacetyl-CoA synthetase protein 20130413 {GO:0007584=IEA, GO:0042493=IEA, GO:0045471=IEA, GO:0034201=IEA, GO:0003824=IEA, GO:0005524=IEA, GO:0014074=IEA, GO:0047760=IEA, GO:0005829=IEA, GO:0001889=IEA, GO:0071397=IEA, GO:0042594=IEA, GO:0071394=IEA, GO:0050872=IEA, GO:0006631=IEA, GO:0032024=IEA, GO:0071333=IEA, GO:0060612=IEA, GO:0030729=IEA} adipose tissue development, cellular response to cholesterol, cellular response to glucose stimulus, cellular response to testosterone stimulus, fatty acid metabolic process, liver development, positive regulation of insulin secretion, response to drug, response to ethanol, response to nutrient, response to oleic acid, response to purine-containing compound, response to starvation, white fat cell differentiation cytosol ATP binding, acetoacetate-CoA ligase activity, butyrate-CoA ligase activity, catalytic activity Human UniProtKB-SubCell:SL-0091 AADAC PINC UniProtKB {GO:0004091=GO_REF:0000002, GO:0004806=GO_REF:0000024, GO:0016787=GO_REF:0000002, GO:0005789=PMID:19339378, GO:0019213=PMID:9665742, GO:0010898=GO_REF:0000024, GO:0017171=PMID:17936933, GO:0050253=GO_REF:0000003, GO:0016021=GO_REF:0000037, GO:0003824=PMID:8063807, GO:0016298=PMID:11481320} P22760 Arylacetamide deacetylase protein 20030904 {GO:0004091=IEA, GO:0004806=ISS, GO:0016787=IEA, GO:0005789=IDA, GO:0019213=IDA, GO:0010898=ISS, GO:0017171=IDA, GO:0050253=IEA, GO:0016021=IEA, GO:0003824=TAS, GO:0016298=TAS} positive regulation of triglyceride catabolic process endoplasmic reticulum membrane, integral to membrane carboxylesterase activity, catalytic activity, deacetylase activity, hydrolase activity, lipase activity, retinyl-palmitate esterase activity, serine hydrolase activity, triglyceride lipase activity Human AADAT Reactome UniProtKB {GO:0006569=Reactome:REACT_916, GO:0070189=PMID:18620547, GO:0009058=GO_REF:0000002, GO:0006536=PMID:18620547, GO:0033512=GO_REF:0000041, GO:0047536=Reactome:REACT_21297, GO:0044281=Reactome:REACT_111217, GO:0003824=GO_REF:0000002, GO:0042803=PMID:18620547, GO:0005739=GO_REF:0000019, GO:0034641=Reactome:REACT_13, GO:0019441=GO_REF:0000019, GO:0005759=Reactome:REACT_25131, GO:0030170=GO_REF:0000019, GO:0006103=PMID:18620547, GO:0016212=Reactome:REACT_25131, GO:0006554=Reactome:REACT_1298} Q8N5Z0 Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial protein 20100701 {GO:0006569=TAS, GO:0070189=IDA, GO:0009058=IEA, GO:0006536=IDA, GO:0033512=IEA, GO:0047536=EXP, GO:0044281=TAS, GO:0003824=IEA, GO:0042803=IPI, GO:0005739=IEA, GO:0034641=TAS, GO:0019441=IEA, GO:0005759=TAS, GO:0030170=IEA, GO:0006103=IDA, GO:0016212=TAS, GO:0006554=TAS} 2-oxoglutarate metabolic process, L-lysine catabolic process to acetyl-CoA via saccharopine, biosynthetic process, cellular nitrogen compound metabolic process, glutamate metabolic process, kynurenine metabolic process, lysine catabolic process, small molecule metabolic process, tryptophan catabolic process, tryptophan catabolic process to kynurenine mitochondrial matrix, mitochondrion 2-aminoadipate transaminase activity, catalytic activity, kynurenine-oxoglutarate transaminase activity, protein homodimerization activity, pyridoxal phosphate binding Human AAGAB LIFEdb UniProtKB {GO:0005737=GO_REF:0000054, GO:0015031=GO_REF:0000037, GO:0005829=GO_REF:0000039} Q6PD74 Alpha- and gamma-adaptin-binding protein p34 protein 20100607 {GO:0005737=IDA, GO:0015031=IEA, GO:0005829=IEA} protein transport cytoplasm, cytosol Human AAK1 IntAct UniProtKB {GO:0005515=PMID:22645275, GO:0045747=PMID:21464124, GO:0035612=PMID:17494869, GO:0030136=GO_REF:0000024, GO:0050821=PMID:21464124, GO:0005112=PMID:21464124, GO:0005524=GO_REF:0000037, GO:0006897=GO_REF:0000037, GO:0032880=PMID:18657069, GO:0005905=GO_REF:0000039, GO:0046777=GO_REF:0000024, GO:0004674=GO_REF:0000024, GO:0043195=GO_REF:0000024, GO:2000369=PMID:17494869, GO:0006468=PMID:17494869, GO:0031252=GO_REF:0000024, GO:0019897=GO_REF:0000024} Q2M2I8 AP2-associated protein kinase 1 protein 20130415 {GO:0005515=IPI, GO:0045747=IDA, GO:0035612=IDA, GO:0030136=ISS, GO:0050821=IDA, GO:0005112=IDA, GO:0005524=IEA, GO:0006897=IEA, GO:0032880=IDA, GO:0005905=IEA, GO:0046777=ISS, GO:0004674=ISS, GO:0043195=ISS, GO:2000369=IMP, GO:0006468=IDA, GO:0031252=ISS, GO:0019897=ISS} endocytosis, positive regulation of Notch signaling pathway, protein autophosphorylation, protein phosphorylation, protein stabilization, regulation of clathrin-mediated endocytosis, regulation of protein localization cell leading edge, clathrin-coated vesicle, coated pit, extrinsic to plasma membrane, terminal bouton AP-2 adaptor complex binding, ATP binding, Notch binding, protein binding, protein serine/threonine kinase activity Human UniProtKB:Q9NQ11 AAMP PINC UniProtKB {GO:0010595=GO_REF:0000024, GO:0005737=GO_REF:0000039, GO:0009986=PMID:10329261, GO:0005886=GO_REF:0000039, GO:0014909=PMID:18634987, GO:0001525=PMID:10329261, GO:0008201=PMID:7743515, GO:0030154=GO_REF:0000037} Q13685 Angio-associated migratory cell protein protein 20030904 {GO:0010595=ISS, GO:0005737=IEA, GO:0009986=IDA, GO:0005886=IEA, GO:0014909=IEP, GO:0001525=NAS, GO:0008201=TAS, GO:0030154=IEA} angiogenesis, cell differentiation, positive regulation of endothelial cell migration, smooth muscle cell migration cell surface, cytoplasm, plasma membrane heparin binding Human AANAT Reactome UniProtKB {GO:0032868=GO_REF:0000019, GO:0051412=GO_REF:0000019, GO:0048471=PMID:11313340, GO:0030187=PMID:11313340, GO:0044281=Reactome:REACT_111217, GO:0010043=GO_REF:0000019, GO:0051591=GO_REF:0000019, GO:0005829=Reactome:REACT_15290, GO:0034641=Reactome:REACT_13, GO:0071889=GO_REF:0000019, GO:0051592=GO_REF:0000019, GO:0005737=GO_REF:0000019, GO:0046219=Reactome:REACT_15439, GO:0034695=GO_REF:0000019, GO:0004060=GO_REF:0000019, GO:0007623=PMID:12736803, GO:0009416=GO_REF:0000019, GO:0004059=PMID:8661026, GO:0071320=PMID:11313340, GO:0034097=GO_REF:0000019, GO:0046688=GO_REF:0000019, GO:0006474=PMID:11313340} Q16613 Serotonin N-acetyltransferase protein 20130301 {GO:0032868=IEA, GO:0051412=IEA, GO:0048471=IDA, GO:0030187=IDA, GO:0044281=TAS, GO:0010043=IEA, GO:0051591=IEA, GO:0005829=TAS, GO:0034641=TAS, GO:0071889=IEA, GO:0051592=IEA, GO:0005737=IEA, GO:0046219=TAS, GO:0034695=IEA, GO:0004060=IEA, GO:0007623=IMP, GO:0009416=IEA, GO:0004059=NAS, GO:0071320=IDA, GO:0034097=IEA, GO:0046688=IEA, GO:0006474=IDA} N-terminal protein amino acid acetylation, cellular nitrogen compound metabolic process, cellular response to cAMP, circadian rhythm, indolalkylamine biosynthetic process, melatonin biosynthetic process, response to cAMP, response to calcium ion, response to copper ion, response to corticosterone stimulus, response to cytokine stimulus, response to insulin stimulus, response to light stimulus, response to prostaglandin E stimulus, response to zinc ion, small molecule metabolic process cytoplasm, cytosol, perinuclear region of cytoplasm 14-3-3 protein binding, aralkylamine N-acetyltransferase activity, arylamine N-acetyltransferase activity Human AARS Reactome UniProtKB {GO:0010467=Reactome:REACT_71, GO:0002161=GO_REF:0000019, GO:0000049=GO_REF:0000019, GO:0006419=GO_REF:0000019, GO:0004813=GO_REF:0000003, GO:0003676=GO_REF:0000002, GO:0005524=GO_REF:0000019, GO:0008033=PMID:7654687, GO:0046872=GO_REF:0000037, GO:0006400=GO_REF:0000019, GO:0006418=Reactome:REACT_15482, GO:0005829=Reactome:REACT_15409, GO:0030968=GO_REF:0000019, GO:0043524=GO_REF:0000019, GO:0005737=PMID:7654687, GO:0006457=GO_REF:0000019, GO:0021680=GO_REF:0000019, GO:0050885=GO_REF:0000019, GO:0043588=GO_REF:0000019, GO:0043200=GO_REF:0000019, GO:0001942=GO_REF:0000019, GO:0016597=GO_REF:0000019} P49588 Alanine--tRNA ligase, cytoplasmic protein 20130301 {GO:0010467=TAS, GO:0002161=IEA, GO:0000049=IEA, GO:0006419=IEA, GO:0004813=IEA, GO:0003676=IEA, GO:0005524=IEA, GO:0008033=TAS, GO:0046872=IEA, GO:0006400=IEA, GO:0006418=TAS, GO:0005829=TAS, GO:0030968=IEA, GO:0043524=IEA, GO:0005737=TAS, GO:0006457=IEA, GO:0021680=IEA, GO:0050885=IEA, GO:0043588=IEA, GO:0043200=IEA, GO:0001942=IEA, GO:0016597=IEA} alanyl-tRNA aminoacylation, cerebellar Purkinje cell layer development, endoplasmic reticulum unfolded protein response, gene expression, hair follicle development, negative regulation of neuron apoptotic process, neuromuscular process controlling balance, protein folding, response to amino acid stimulus, skin development, tRNA aminoacylation for protein translation, tRNA modification, tRNA processing cytoplasm, cytosol ATP binding, alanine-tRNA ligase activity, amino acid binding, aminoacyl-tRNA editing activity, metal ion binding, nucleic acid binding, tRNA binding Human AARS2 BHF-UCL UniProtKB {GO:0005739=GO_REF:0000052, GO:0010467=Reactome:REACT_71, GO:0000049=GO_REF:0000037, GO:0033108=PMID:21549344, GO:0070143=PMID:21549344, GO:0004813=PMID:21549344, GO:0005524=GO_REF:0000037, GO:0046872=GO_REF:0000037, GO:0006418=Reactome:REACT_15482} Q5JTZ9 Alanine--tRNA ligase, mitochondrial protein 20120510 {GO:0005739=IDA, GO:0010467=TAS, GO:0000049=IEA, GO:0033108=IMP, GO:0070143=IMP, GO:0004813=IMP, GO:0005524=IEA, GO:0046872=IEA, GO:0006418=TAS} gene expression, mitochondrial alanyl-tRNA aminoacylation, mitochondrial respiratory chain complex assembly, tRNA aminoacylation for protein translation mitochondrion ATP binding, alanine-tRNA ligase activity, metal ion binding, tRNA binding Human AARSD1 BHF-UCL UniProtKB {GO:0003674=GO_REF:0000015, GO:0008150=GO_REF:0000015, GO:0005737=GO_REF:0000039, GO:0000166=GO_REF:0000002, GO:0006419=GO_REF:0000002, GO:0004813=GO_REF:0000002, GO:0005575=GO_REF:0000015, GO:0003676=GO_REF:0000002, GO:0043039=GO_REF:0000002, GO:0005524=GO_REF:0000002, GO:0046872=GO_REF:0000037, GO:0016876=GO_REF:0000002} Q9BTE6 Alanyl-tRNA editing protein Aarsd1 protein 20120510 {GO:0003674=ND, GO:0008150=ND, GO:0005737=IEA, GO:0000166=IEA, GO:0006419=IEA, GO:0004813=IEA, GO:0005575=ND, GO:0003676=IEA, GO:0043039=IEA, GO:0005524=IEA, GO:0046872=IEA, GO:0016876=IEA} alanyl-tRNA aminoacylation, biological_process, tRNA aminoacylation cellular_component, cytoplasm ATP binding, alanine-tRNA ligase activity, ligase activity, forming aminoacyl-tRNA and related compounds, metal ion binding, molecular_function, nucleic acid binding, nucleotide binding Human AASDHPPT Reactome UniProtKB {GO:0005515=PMID:18022563, GO:0000287=PMID:18022563, GO:0015939=Reactome:REACT_11172, GO:0006766=Reactome:REACT_11193, GO:0009059=GO_REF:0000002, GO:0006767=Reactome:REACT_11238, GO:0006633=GO_REF:0000002, GO:0044281=Reactome:REACT_111217, GO:0008897=PMID:18022563, GO:0005829=Reactome:REACT_11175} Q9NRN7 L-aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase protein 20130301 {GO:0005515=IPI, GO:0000287=IDA, GO:0015939=TAS, GO:0006766=TAS, GO:0009059=IEA, GO:0006767=TAS, GO:0006633=IEA, GO:0044281=TAS, GO:0008897=IDA, GO:0005829=TAS} fatty acid biosynthetic process, macromolecule biosynthetic process, pantothenate metabolic process, small molecule metabolic process, vitamin metabolic process, water-soluble vitamin metabolic process cytosol "holo-acyl-carrier-protein"" synthase activity, magnesium ion binding, protein binding""" Human AASS HPA UniProtKB {GO:0005739=GO_REF:0000052, GO:0034641=Reactome:REACT_13, GO:0005737=GO_REF:0000052, GO:0051262=PMID:10567240, GO:0033512=GO_REF:0000041, GO:0005759=Reactome:REACT_2132, GO:0016491=GO_REF:0000002, GO:0047130=Reactome:REACT_75, GO:0047131=Reactome:REACT_2132, GO:0044281=Reactome:REACT_111217, GO:0006554=Reactome:REACT_1298, GO:0043231=GO_REF:0000052} Q9UDR5 Alpha-aminoadipic semialdehyde synthase, mitochondrial protein 20101115 {GO:0005739=IDA, GO:0034641=TAS, GO:0005737=IDA, GO:0051262=TAS, GO:0033512=IEA, GO:0005759=TAS, GO:0016491=IEA, GO:0047130=EXP, GO:0047131=EXP, GO:0044281=TAS, GO:0006554=TAS, GO:0043231=IDA} L-lysine catabolic process to acetyl-CoA via saccharopine, cellular nitrogen compound metabolic process, lysine catabolic process, protein tetramerization, small molecule metabolic process cytoplasm, intracellular membrane-bounded organelle, mitochondrial matrix, mitochondrion oxidoreductase activity, saccharopine dehydrogenase (NAD+, L-glutamate-forming) activity, saccharopine dehydrogenase (NADP+, L-lysine-forming) activity Human AATF HPA UniProtKB {GO:0005515=PMID:17157788, GO:0005813=GO_REF:0000052, GO:0048011=Reactome:REACT_13776, GO:0043066=PMID:15207272, GO:0005794=GO_REF:0000019, GO:0003700=PMID:10580117, GO:0042254=GO_REF:0000019, GO:0005730=GO_REF:0000052, GO:0048156=GO_REF:0000019, GO:0006915=Reactome:REACT_13638, GO:0032929=PMID:15207272, GO:0005634=GO_REF:0000052, GO:0097190=Reactome:REACT_13720, GO:0042985=GO_REF:0000019, GO:0006974=PMID:18049476, GO:0043522=PMID:14627703, GO:0007346=GO_REF:0000019, GO:0005737=PMID:15207272, GO:0040016=GO_REF:0000019, GO:0045944=PMID:18049476, GO:2000378=PMID:15207272, GO:0007155=GO_REF:0000019, GO:0005925=GO_REF:0000052} Q9NY61 Protein AATF protein 20101115 {GO:0005515=IPI, GO:0005813=IDA, GO:0048011=TAS, GO:0043066=IMP, GO:0005794=IEA, GO:0003700=IDA, GO:0042254=IEA, GO:0005730=IDA, GO:0048156=IEA, GO:0006915=TAS, GO:0032929=IDA, GO:0005634=IDA, GO:0097190=TAS, GO:0042985=IEA, GO:0006974=IEP, GO:0043522=IPI, GO:0007346=IEA, GO:0005737=IDA, GO:0040016=IEA, GO:0045944=IDA, GO:2000378=IDA, GO:0007155=IEA, GO:0005925=IDA} apoptotic process, apoptotic signaling pathway, cell adhesion, embryonic cleavage, negative regulation of amyloid precursor protein biosynthetic process, negative regulation of apoptotic process, negative regulation of reactive oxygen species metabolic process, negative regulation of superoxide anion generation, neurotrophin TRK receptor signaling pathway, positive regulation of transcription from RNA polymerase II promoter, regulation of mitotic cell cycle, response to DNA damage stimulus, ribosome biogenesis Golgi apparatus, centrosome, cytoplasm, focal adhesion, nucleolus, nucleus leucine zipper domain binding, protein binding, sequence-specific DNA binding transcription factor activity, tau protein binding Human AATK HPA UniProtKB {GO:0005739=GO_REF:0000052, GO:0048471=GO_REF:0000039, GO:0046777=GO_REF:0000019, GO:0004674=GO_REF:0000037, GO:0006915=GO_REF:0000019, GO:0016021=GO_REF:0000037, GO:0004713=GO_REF:0000002, GO:0005524=GO_REF:0000037} Q6ZMQ8 Serine/threonine-protein kinase LMTK1 protein 20080205 {GO:0005739=IDA, GO:0048471=IEA, GO:0046777=IEA, GO:0004674=IEA, GO:0006915=IEA, GO:0016021=IEA, GO:0004713=IEA, GO:0005524=IEA} apoptotic process, protein autophosphorylation integral to membrane, mitochondrion, perinuclear region of cytoplasm ATP binding, protein serine/threonine kinase activity, protein tyrosine kinase activity Human ABAT LIFEdb UniProtKB {GO:0001666=GO_REF:0000019, GO:0043005=GO_REF:0000019, GO:0003867=Reactome:REACT_23980, GO:0042493=GO_REF:0000019, GO:0045471=GO_REF:0000019, GO:0007268=Reactome:REACT_13685, GO:0048148=GO_REF:0000024, GO:0045776=GO_REF:0000019, GO:0047298=GO_REF:0000003, GO:0007269=Reactome:REACT_13723, GO:0042803=PMID:15528998, GO:0005739=GO_REF:0000054, GO:0032145=GO_REF:0000024, GO:0032144=PMID:15528998, GO:0005759=Reactome:REACT_23980, GO:0030170=PMID:15650327, GO:0010039=GO_REF:0000019, GO:0007610=PMID:11918424, GO:0009450=PMID:15528998, GO:0007626=GO_REF:0000019, GO:0042135=PMID:15528998, GO:0007620=GO_REF:0000019, GO:0009448=GO_REF:0000002, GO:0035094=GO_REF:0000019} P80404 4-aminobutyrate aminotransferase, mitochondrial protein 20100607 {GO:0001666=IEA, GO:0043005=IEA, GO:0003867=TAS, GO:0042493=IEA, GO:0045471=IEA, GO:0007268=TAS, GO:0048148=ISS, GO:0045776=IEA, GO:0047298=IEA, GO:0007269=TAS, GO:0042803=IPI, GO:0005739=IDA, GO:0032145=ISS, GO:0032144=IDA, GO:0005759=TAS, GO:0030170=IDA, GO:0010039=IEA, GO:0007610=NAS, GO:0009450=NAS, GO:0007626=IEA, GO:0042135=NAS, GO:0007620=IEA, GO:0009448=IEA, GO:0035094=IEA} behavior, behavioral response to cocaine, copulation, gamma-aminobutyric acid catabolic process, gamma-aminobutyric acid metabolic process, locomotory behavior, negative regulation of blood pressure, neurotransmitter catabolic process, neurotransmitter secretion, response to drug, response to ethanol, response to hypoxia, response to iron ion, response to nicotine, synaptic transmission 4-aminobutyrate transaminase complex, mitochondrial matrix, mitochondrion, neuron projection (S)-3-amino-2-methylpropionate transaminase activity, 4-aminobutyrate transaminase activity, protein homodimerization activity, pyridoxal phosphate binding, succinate-semialdehyde dehydrogenase binding Human ABCA1 GOC UniProtKB {GO:0005515=PMID:12084722, GO:0008509=GO_REF:0000024, GO:0031267=PMID:16443932, GO:0071300=GO_REF:0000019, GO:0006497=GO_REF:0000019, GO:0044255=Reactome:REACT_22279, GO:0042632=PMID:10431236, GO:0019905=PMID:15469992, GO:0033344=PMID:11162594, GO:0005794=GO_REF:0000019, GO:0010745=PMID:18490524, GO:0050702=PMID:11855831, GO:0043691=PMID:10431236, GO:0005548=PMID:16702602, GO:0038027=PMID:16443932, GO:0055098=PMID:15358760, GO:0007186=PMID:16443932, GO:0005887=PMID:10525055, GO:0042157=Reactome:REACT_13621, GO:0055091=PMID:16702602, GO:0045121=PMID:15469992, GO:0007040=PMID:15163665, GO:0032367=PMID:10431236, GO:0006629=Reactome:REACT_602, GO:0005886=Reactome:REACT_115994, GO:0030819=PMID:14701824, GO:0017127=PMID:12084722, GO:0030139=PMID:14747463, GO:0044281=Reactome:REACT_111217, GO:0010875=GO_REF:0000019, GO:0045332=GO_REF:0000019, GO:0005543=PMID:16702602, GO:0015485=PMID:12084722, GO:0016197=PMID:14747463, GO:0034380=PMID:17305370, GO:0016887=GO_REF:0000002, GO:0008203=PMID:14747463, GO:0002790=GO_REF:0000019, GO:0032489=PMID:16443932, GO:0005524=PMID:11700048, GO:0006911=GO_REF:0000019, GO:0010887=PMID:18490524, GO:0045335=PMID:15469992, GO:0033700=PMID:11162594, GO:0071222=GO_REF:0000019, GO:0034616=PMID:15358760, GO:0060155=PMID:15163665, GO:0034185=PMID:11162594, GO:0034186=PMID:11162594, GO:0034188=PMID:16443932} O95477 ATP-binding cassette sub-family A member 1 protein 20130413 {GO:0005515=IPI, GO:0008509=ISS, GO:0031267=IPI, GO:0071300=IEA, GO:0006497=IEA, GO:0044255=TAS, GO:0042632=IDA, GO:0019905=IPI, GO:0033344=IDA, GO:0005794=IEA, GO:0010745=TAS, GO:0050702=IMP, GO:0043691=IMP, GO:0005548=IDA, GO:0038027=IDA, GO:0055098=IEP, GO:0007186=IMP, GO:0005887=IDA, GO:0042157=TAS, GO:0055091=IMP, GO:0045121=IDA, GO:0007040=IDA, GO:0032367=IMP, GO:0006629=TAS, GO:0005886=TAS, GO:0030819=IMP, GO:0017127=IDA, GO:0030139=IDA, GO:0044281=TAS, GO:0010875=IEA, GO:0045332=IEA, GO:0005543=IC, GO:0015485=IC, GO:0016197=IDA, GO:0034380=IMP, GO:0016887=IEA, GO:0008203=IDA, GO:0002790=IEA, GO:0032489=IMP, GO:0005524=IDA, GO:0006911=IEA, GO:0010887=TAS, GO:0045335=IDA, GO:0033700=IDA, GO:0071222=IEA, GO:0034616=IEP, GO:0060155=IMP, GO:0034185=IPI, GO:0034186=IPI, GO:0034188=IDA} G-protein coupled receptor signaling pathway, apolipoprotein A-I-mediated signaling pathway, cellular lipid metabolic process, cellular response to lipopolysaccharide, cellular response to retinoic acid, cholesterol efflux, cholesterol homeostasis, cholesterol metabolic process, endosomal transport, high-density lipoprotein particle assembly, interleukin-1 beta secretion, intracellular cholesterol transport, lipid metabolic process, lipoprotein metabolic process, lysosome organization, negative regulation of cholesterol storage, negative regulation of macrophage derived foam cell differentiation, peptide secretion, phagocytosis, engulfment, phospholipid efflux, phospholipid homeostasis, phospholipid translocation, platelet dense granule organization, positive regulation of cAMP biosynthetic process, positive regulation of cholesterol efflux, protein lipidation, regulation of Cdc42 protein signal transduction, response to laminar fluid shear stress, response to low-density lipoprotein particle stimulus, reverse cholesterol transport, small molecule metabolic process Golgi apparatus, endocytic vesicle, integral to plasma membrane, membrane raft, phagocytic vesicle, plasma membrane ATP binding, ATPase activity, anion transmembrane transporter activity, apolipoprotein A-I binding, apolipoprotein A-I receptor activity, apolipoprotein binding, cholesterol binding, cholesterol transporter activity, phospholipid binding, phospholipid transporter activity, protein binding, small GTPase binding, syntaxin binding Human ABCA10 UniProtKB UniProtKB {GO:0006810=GO_REF:0000037, GO:0016021=GO_REF:0000037, GO:0005524=GO_REF:0000037, GO:0016887=GO_REF:0000002} Q8WWZ4 ATP-binding cassette sub-family A member 10 protein 20130413 {GO:0006810=IEA, GO:0016021=IEA, GO:0005524=IEA, GO:0016887=IEA} transport integral to membrane ATP binding, ATPase activity Human UniProtKB-KW:KW-0812 ABCA12 UniProtKB UniProtKB {GO:0019725=PMID:12697999, GO:0035627=GO_REF:0000019, GO:0048286=GO_REF:0000019, GO:0005743=GO_REF:0000019, GO:0031424=GO_REF:0000019, GO:0055088=GO_REF:0000019, GO:0061436=GO_REF:0000019, GO:0005524=PMID:12697999, GO:0005829=GO_REF:0000019, GO:0006869=PMID:12915478, GO:0043129=GO_REF:0000019, GO:0016021=PMID:12697999, GO:0016887=GO_REF:0000002} Q86UK0 ATP-binding cassette sub-family A member 12 protein 20050704 {GO:0019725=NAS, GO:0035627=IEA, GO:0048286=IEA, GO:0005743=IEA, GO:0031424=IEA, GO:0055088=IEA, GO:0061436=IEA, GO:0005524=NAS, GO:0005829=IEA, GO:0006869=NAS, GO:0043129=IEA, GO:0016021=NAS, GO:0016887=IEA} cellular homeostasis, ceramide transport, establishment of skin barrier, keratinization, lipid homeostasis, lipid transport, lung alveolus development, surfactant homeostasis cytosol, integral to membrane, mitochondrial inner membrane ATP binding, ATPase activity Human ABCA13 UniProtKB UniProtKB {GO:0006810=GO_REF:0000037, GO:0016021=GO_REF:0000037, GO:0005524=GO_REF:0000037, GO:0016887=GO_REF:0000002} Q86UQ4 ATP-binding cassette sub-family A member 13 protein 20130413 {GO:0006810=IEA, GO:0016021=IEA, GO:0005524=IEA, GO:0016887=IEA} transport integral to membrane ATP binding, ATPase activity Human UniProtKB-KW:KW-0812 ABCA2 GOC UniProtKB {GO:0042632=PMID:15238223, GO:0006629=PMID:11178988, GO:0006200=PMID:15999530, GO:0005815=GO_REF:0000024, GO:0006357=PMID:15238223, GO:0042493=PMID:12363033, GO:0042626=PMID:7766993, GO:0048545=PMID:15238223, GO:0005765=PMID:11309290, GO:0005764=PMID:11309290, GO:0005524=GO_REF:0000024, GO:0000166=PMID:12363033, GO:0006810=PMID:7766993, GO:0016023=GO_REF:0000024, GO:0016021=PMID:12363033, GO:0032383=PMID:15238223, GO:0016887=PMID:15999530, GO:0043190=PMID:11178988, GO:0010008=GO_REF:0000039, GO:0005768=PMID:11309290} Q9BZC7 ATP-binding cassette sub-family A member 2 protein 20130413 {GO:0042632=IEP, GO:0006629=NAS, GO:0006200=IDA, GO:0005815=ISS, GO:0006357=IDA, GO:0042493=TAS, GO:0042626=NAS, GO:0048545=IEP, GO:0005765=RCA, GO:0005764=IDA, GO:0005524=ISS, GO:0000166=RCA, GO:0006810=NAS, GO:0016023=ISS, GO:0016021=RCA, GO:0032383=IMP, GO:0016887=IDA, GO:0043190=NAS, GO:0010008=IEA, GO:0005768=IDA} ATP catabolic process, cholesterol homeostasis, lipid metabolic process, regulation of intracellular cholesterol transport, regulation of transcription from RNA polymerase II promoter, response to drug, response to steroid hormone stimulus, transport ATP-binding cassette (ABC) transporter complex, cytoplasmic membrane-bounded vesicle, endosome, endosome membrane, integral to membrane, lysosomal membrane, lysosome, microtubule organizing center ATP binding, ATPase activity, ATPase activity, coupled to transmembrane movement of substances, nucleotide binding Human ABCA3 Reactome UniProtKB {GO:0005215=PMID:9027511, GO:0097233=GO_REF:0000019, GO:0005886=Reactome:REACT_111169, GO:0016020=PMID:9027511, GO:0097208=PMID:11718719, GO:0042493=PMID:8706931, GO:0006810=PMID:15531465, GO:0042626=PMID:9027511, GO:0016021=GO_REF:0000037, GO:0055085=Reactome:REACT_15518, GO:0005524=GO_REF:0000037, GO:0016887=GO_REF:0000002} Q99758 ATP-binding cassette sub-family A member 3 protein 20130301 {GO:0005215=TAS, GO:0097233=IEA, GO:0005886=TAS, GO:0016020=TAS, GO:0097208=IDA, GO:0042493=TAS, GO:0006810=IDA, GO:0042626=TAS, GO:0016021=IEA, GO:0055085=TAS, GO:0005524=IEA, GO:0016887=IEA} response to drug, transmembrane transport, transport alveolar lamellar body, alveolar lamellar body membrane, integral to membrane, membrane, plasma membrane ATP binding, ATPase activity, ATPase activity, coupled to transmembrane movement of substances, transporter activity Human ABCA4 Reactome UniProtKB {GO:0005215=PMID:9054934, GO:0006649=GO_REF:0000019, GO:0007603=Reactome:REACT_160125, GO:0042626=GO_REF:0000002, GO:0045494=GO_REF:0000019, GO:0055085=Reactome:REACT_15518, GO:0005524=GO_REF:0000037, GO:0001523=Reactome:REACT_160156, GO:0097381=Reactome:REACT_111189, GO:0016020=PMID:9054934, GO:0005887=GO_REF:0000002, GO:0004012=GO_REF:0000019, GO:0006810=PMID:9054934, GO:0016887=GO_REF:0000002, GO:0007601=PMID:9425888} P78363 Retinal-specific ATP-binding cassette transporter protein 20121026 {GO:0005215=TAS, GO:0006649=IEA, GO:0007603=TAS, GO:0042626=IEA, GO:0045494=IEA, GO:0055085=TAS, GO:0005524=IEA, GO:0001523=TAS, GO:0097381=TAS, GO:0016020=TAS, GO:0005887=IEA, GO:0004012=IEA, GO:0006810=TAS, GO:0016887=IEA, GO:0007601=TAS} phospholipid transfer to membrane, photoreceptor cell maintenance, phototransduction, visible light, retinoid metabolic process, transmembrane transport, transport, visual perception integral to plasma membrane, membrane, photoreceptor disc membrane ATP binding, ATPase activity, ATPase activity, coupled to transmembrane movement of substances, phospholipid-translocating ATPase activity, transporter activity Human ABCA5 BHF-UCL UniProtKB {GO:0033344=PMID:20382126, GO:0010745=PMID:20382126, GO:0000139=GO_REF:0000039, GO:0005770=PMID:15870284, GO:0043691=PMID:20382126, GO:0034375=PMID:20382126, GO:0031902=GO_REF:0000039, GO:0016021=GO_REF:0000037, GO:0005765=GO_REF:0000039, GO:0005764=PMID:15870284, GO:0005524=GO_REF:0000037, GO:0016887=GO_REF:0000002} Q8WWZ7 ATP-binding cassette sub-family A member 5 protein 20100601 {GO:0033344=ISS, GO:0010745=ISS, GO:0000139=IEA, GO:0005770=ISS, GO:0043691=IC, GO:0034375=ISS, GO:0031902=IEA, GO:0016021=IEA, GO:0005765=IEA, GO:0005764=ISS, GO:0005524=IEA, GO:0016887=IEA} cholesterol efflux, high-density lipoprotein particle remodeling, negative regulation of macrophage derived foam cell differentiation, reverse cholesterol transport Golgi membrane, integral to membrane, late endosome, late endosome membrane, lysosomal membrane, lysosome ATP binding, ATPase activity Human GO:0034375 ABCA6 UniProtKB UniProtKB {GO:0006810=GO_REF:0000037, GO:0016021=GO_REF:0000037, GO:0005524=GO_REF:0000037, GO:0016887=GO_REF:0000002} Q8N139 ATP-binding cassette sub-family A member 6 protein 20130413 {GO:0006810=IEA, GO:0016021=IEA, GO:0005524=IEA, GO:0016887=IEA} transport integral to membrane ATP binding, ATPase activity Human UniProtKB-KW:KW-0812 ABCA7 HPA UniProtKB {GO:0006909=GO_REF:0000037, GO:0005215=PMID:10873640, GO:0005794=GO_REF:0000052, GO:0005886=GO_REF:0000052, GO:0005548=GO_REF:0000019, GO:0055085=Reactome:REACT_15518, GO:0005524=GO_REF:0000037, GO:0005622=GO_REF:0000019, GO:0033700=GO_REF:0000019, GO:0005737=GO_REF:0000052, GO:0016324=GO_REF:0000019, GO:0000139=GO_REF:0000039, GO:0016021=GO_REF:0000037, GO:0016887=GO_REF:0000002, GO:0043190=PMID:10873640, GO:0010008=GO_REF:0000039} Q8IZY2 ATP-binding cassette sub-family A member 7 protein 20110516 {GO:0006909=IEA, GO:0005215=TAS, GO:0005794=IDA, GO:0005886=IDA, GO:0005548=IEA, GO:0055085=TAS, GO:0005524=IEA, GO:0005622=IEA, GO:0033700=IEA, GO:0005737=IDA, GO:0016324=IEA, GO:0000139=IEA, GO:0016021=IEA, GO:0016887=IEA, GO:0043190=TAS, GO:0010008=IEA} phagocytosis, phospholipid efflux, transmembrane transport ATP-binding cassette (ABC) transporter complex, Golgi apparatus, Golgi membrane, apical plasma membrane, cytoplasm, endosome membrane, integral to membrane, intracellular, plasma membrane ATP binding, ATPase activity, phospholipid transporter activity, transporter activity Human ABCA9 ENSEMBL UniProtKB {GO:0005739=GO_REF:0000019, GO:0006810=GO_REF:0000037, GO:0016021=GO_REF:0000037, GO:0005524=GO_REF:0000037, GO:0016887=GO_REF:0000002} Q8IUA7 ATP-binding cassette sub-family A member 9 protein 20130413 {GO:0005739=IEA, GO:0006810=IEA, GO:0016021=IEA, GO:0005524=IEA, GO:0016887=IEA} transport integral to membrane, mitochondrion ATP binding, ATPase activity Human Ensembl:ENSMUSP00000036338 ABCB1 IntAct UniProtKB {GO:0005515=PMID:20711237, GO:0005215=PMID:3022150, GO:0005886=Reactome:REACT_111164, GO:0009986=PMID:12493773, GO:0042493=PMID:3022150, GO:0072089=PMID:19384922, GO:0042626=GO_REF:0000033, GO:0044281=Reactome:REACT_111217, GO:0005524=GO_REF:0000037, GO:0055085=Reactome:REACT_15518, GO:0008559=GO_REF:0000003, GO:0016324=GO_REF:0000033, GO:0046581=GO_REF:0000033, GO:0000139=GO_REF:0000033, GO:0016020=PMID:3022150, GO:0006855=Reactome:REACT_120801, GO:0000086=PMID:19384922, GO:0006810=PMID:3022150, GO:0016021=GO_REF:0000033} P08183 Multidrug resistance protein 1 protein 20130415 {GO:0005515=IPI, GO:0005215=TAS, GO:0005886=TAS, GO:0009986=IDA, GO:0042493=TAS, GO:0072089=IMP, GO:0042626=IBA, GO:0044281=TAS, GO:0005524=IEA, GO:0055085=TAS, GO:0008559=IEA, GO:0016324=IBA, GO:0046581=IBA, GO:0000139=IBA, GO:0016020=TAS, GO:0006855=TAS, GO:0000086=IDA, GO:0006810=TAS, GO:0016021=IBA} G2/M transition of mitotic cell cycle, drug transmembrane transport, response to drug, small molecule metabolic process, stem cell proliferation, transmembrane transport, transport Golgi membrane, apical plasma membrane, cell surface, integral to membrane, intercellular canaliculus, membrane, plasma membrane ATP binding, ATPase activity, coupled to transmembrane movement of substances, protein binding, transporter activity, xenobiotic-transporting ATPase activity Human UniProtKB:Q86VI4 ABCB10 UniProtKB UniProtKB {GO:0005215=PMID:10922475, GO:0005886=GO_REF:0000033, GO:0032592=PMID:10922475, GO:0006810=PMID:10922475, GO:0005743=GO_REF:0000033, GO:0055085=GO_REF:0000033, GO:0005524=GO_REF:0000037, GO:0015421=GO_REF:0000033, GO:0042803=GO_REF:0000019} Q9NRK6 ATP-binding cassette sub-family B member 10, mitochondrial protein 20100208 {GO:0005215=NAS, GO:0005886=IRD, GO:0032592=IDA, GO:0006810=NAS, GO:0005743=IBA, GO:0055085=IBA, GO:0005524=IEA, GO:0015421=IBA, GO:0042803=IEA} transmembrane transport, transport integral to mitochondrial membrane, mitochondrial inner membrane, plasma membrane ATP binding, oligopeptide-transporting ATPase activity, protein homodimerization activity, transporter activity Human ABCB11 Reactome UniProtKB {GO:0005215=PMID:9806540, GO:0005886=Reactome:REACT_10101, GO:0006699=Reactome:REACT_11054, GO:0042626=GO_REF:0000033, GO:0015126=GO_REF:0000033, GO:0044281=Reactome:REACT_111217, GO:0005524=GO_REF:0000037, GO:0055085=GO_REF:0000033, GO:0016324=GO_REF:0000033, GO:0046581=GO_REF:0000033, GO:0016020=PMID:9806540, GO:0000139=GO_REF:0000033, GO:0005887=PMID:9806540, GO:0015721=Reactome:REACT_11042, GO:0015722=GO_REF:0000033, GO:0008554=PMID:9806540, GO:0015432=PMID:9806540, GO:0006810=PMID:9806540, GO:0008206=Reactome:REACT_11040, GO:0016021=GO_REF:0000033} O95342 Bile salt export pump protein 20130301 {GO:0005215=TAS, GO:0005886=TAS, GO:0006699=TAS, GO:0042626=IBA, GO:0015126=IBA, GO:0044281=TAS, GO:0005524=IEA, GO:0055085=IBA, GO:0016324=IBA, GO:0046581=IBA, GO:0016020=TAS, GO:0000139=IBA, GO:0005887=TAS, GO:0015721=TAS, GO:0015722=IBA, GO:0008554=TAS, GO:0015432=TAS, GO:0006810=TAS, GO:0008206=TAS, GO:0016021=IBA} bile acid and bile salt transport, bile acid biosynthetic process, bile acid metabolic process, canalicular bile acid transport, small molecule metabolic process, transmembrane transport, transport Golgi membrane, apical plasma membrane, integral to membrane, integral to plasma membrane, intercellular canaliculus, membrane, plasma membrane ATP binding, ATPase activity, coupled to transmembrane movement of substances, bile acid-exporting ATPase activity, canalicular bile acid transmembrane transporter activity, sodium-exporting ATPase activity, phosphorylative mechanism, transporter activity Human ABCB4 Reactome UniProtKB {GO:0006629=PMID:7912658, GO:0005886=Reactome:REACT_115807, GO:0042493=PMID:7912658, GO:0042626=GO_REF:0000033, GO:0044281=Reactome:REACT_111217, GO:0005524=GO_REF:0000037, GO:0055085=GO_REF:0000033, GO:0046581=GO_REF:0000033, GO:0008559=GO_REF:0000003, GO:0016324=GO_REF:0000033, GO:0016020=PMID:7912658, GO:0000139=GO_REF:0000033, GO:0005887=PMID:7912658, GO:0006810=PMID:8106172, GO:0016021=GO_REF:0000033, GO:0044255=Reactome:REACT_22279} P21439 Multidrug resistance protein 3 protein 20130301 {GO:0006629=TAS, GO:0005886=TAS, GO:0042493=TAS, GO:0042626=IBA, GO:0044281=TAS, GO:0005524=IEA, GO:0055085=IBA, GO:0046581=IBA, GO:0008559=IEA, GO:0016324=IBA, GO:0016020=TAS, GO:0000139=IBA, GO:0005887=TAS, GO:0006810=TAS, GO:0016021=IBA, GO:0044255=TAS} cellular lipid metabolic process, lipid metabolic process, response to drug, small molecule metabolic process, transmembrane transport, transport Golgi membrane, apical plasma membrane, integral to membrane, integral to plasma membrane, intercellular canaliculus, membrane, plasma membrane ATP binding, ATPase activity, coupled to transmembrane movement of substances, xenobiotic-transporting ATPase activity Human ABCB5 Reactome UniProtKB {GO:0046581=GO_REF:0000033, GO:0016324=GO_REF:0000033, GO:0005886=Reactome:REACT_111164, GO:0015562=PMID:12960149, GO:0000139=GO_REF:0000033, GO:0005887=PMID:12960149, GO:0042391=PMID:12960149, GO:0042626=GO_REF:0000033, GO:0016021=GO_REF:0000002, GO:0055085=Reactome:REACT_15518, GO:0005524=GO_REF:0000037} Q2M3G0 ATP-binding cassette sub-family B member 5 protein 20130301 {GO:0046581=IBA, GO:0016324=IBA, GO:0005886=TAS, GO:0015562=IDA, GO:0000139=IBA, GO:0005887=IDA, GO:0042391=IDA, GO:0042626=IBA, GO:0016021=IEA, GO:0055085=TAS, GO:0005524=IEA} regulation of membrane potential, transmembrane transport Golgi membrane, apical plasma membrane, integral to membrane, integral to plasma membrane, intercellular canaliculus, plasma membrane ATP binding, ATPase activity, coupled to transmembrane movement of substances, efflux transmembrane transporter activity Human ABCB6 Reactome UniProtKB {GO:0015886=PMID:17661442, GO:0015439=PMID:17006453, GO:0005886=PMID:17661442, GO:0015562=PMID:17661442, GO:0015232=Reactome:REACT_111156, GO:0005783=PMID:22226084, GO:0071585=GO_REF:0000033, GO:0042626=GO_REF:0000002, GO:0005741=Reactome:REACT_111156, GO:0005740=PMID:10837493, GO:0006879=PMID:11977179, GO:0005739=PMID:18279659, GO:0070574=GO_REF:0000033, GO:0006810=PMID:10837493, GO:0043190=PMID:11955620, GO:0005774=GO_REF:0000033, GO:0005794=PMID:22226084, GO:0005524=PMID:10837493, GO:0055085=Reactome:REACT_15518, GO:0006779=PMID:17006453, GO:0007420=PMID:22100072, GO:0043588=PMID:22100072, GO:0016021=GO_REF:0000002, GO:0031307=PMID:17661442, GO:0020037=PMID:17006453} Q9NP58 ATP-binding cassette sub-family B member 6, mitochondrial protein 20110704 {GO:0015886=IDA, GO:0015439=IMP, GO:0005886=IDA, GO:0015562=IDA, GO:0015232=TAS, GO:0005783=IDA, GO:0071585=IBA, GO:0042626=IEA, GO:0005741=TAS, GO:0005740=IDA, GO:0006879=NAS, GO:0005739=IDA, GO:0070574=IBA, GO:0006810=IDA, GO:0043190=NAS, GO:0005774=IBA, GO:0005794=IDA, GO:0005524=IDA, GO:0055085=TAS, GO:0006779=IDA, GO:0007420=IMP, GO:0043588=IMP, GO:0016021=IEA, GO:0031307=IDA, GO:0020037=IDA} brain development, cadmium ion transmembrane transport, cellular iron ion homeostasis, detoxification of cadmium ion, heme transport, porphyrin-containing compound biosynthetic process, skin development, transmembrane transport, transport ATP-binding cassette (ABC) transporter complex, Golgi apparatus, endoplasmic reticulum, integral to membrane, integral to mitochondrial outer membrane, mitochondrial envelope, mitochondrial outer membrane, mitochondrion, plasma membrane, vacuolar membrane ATP binding, ATPase activity, coupled to transmembrane movement of substances, efflux transmembrane transporter activity, heme binding, heme transporter activity, heme-transporting ATPase activity Human ABCB7 GOC UniProtKB {GO:0006879=GO_REF:0000033, GO:0005739=GO_REF:0000052, GO:0015886=PMID:9621516, GO:0005737=GO_REF:0000052, GO:0015232=PMID:9621516, GO:0006810=PMID:9621516, GO:0005743=Reactome:REACT_22342, GO:0042626=GO_REF:0000033, GO:0044281=Reactome:REACT_111217, GO:0016021=GO_REF:0000033, GO:0055085=Reactome:REACT_15518, GO:0005524=GO_REF:0000037} O75027 ATP-binding cassette sub-family B member 7, mitochondrial protein 20130413 {GO:0006879=IBA, GO:0005739=IDA, GO:0015886=TAS, GO:0005737=IDA, GO:0015232=TAS, GO:0006810=TAS, GO:0005743=TAS, GO:0042626=IBA, GO:0044281=TAS, GO:0016021=IBA, GO:0055085=TAS, GO:0005524=IEA} cellular iron ion homeostasis, heme transport, small molecule metabolic process, transmembrane transport, transport cytoplasm, integral to membrane, mitochondrial inner membrane, mitochondrion ATP binding, ATPase activity, coupled to transmembrane movement of substances, heme transporter activity Human ABCB8 HPA UniProtKB {GO:0005215=PMID:9878413, GO:0005730=GO_REF:0000052, GO:0005743=GO_REF:0000039, GO:0042626=GO_REF:0000033, GO:0005634=GO_REF:0000052, GO:0005740=PMID:9878413, GO:0005524=GO_REF:0000037, GO:0055085=GO_REF:0000033, GO:0005739=GO_REF:0000052, GO:0016020=PMID:9878413, GO:0006810=PMID:9878413, GO:0016021=GO_REF:0000033, GO:0043190=PMID:9878413} Q9NUT2 ATP-binding cassette sub-family B member 8, mitochondrial protein 20111111 {GO:0005215=TAS, GO:0005730=IDA, GO:0005743=IEA, GO:0042626=IBA, GO:0005634=IDA, GO:0005740=TAS, GO:0005524=IEA, GO:0055085=IBA, GO:0005739=IDA, GO:0016020=TAS, GO:0006810=TAS, GO:0016021=IBA, GO:0043190=TAS} transmembrane transport, transport ATP-binding cassette (ABC) transporter complex, integral to membrane, membrane, mitochondrial envelope, mitochondrial inner membrane, mitochondrion, nucleolus, nucleus ATP binding, ATPase activity, coupled to transmembrane movement of substances, transporter activity Human ABCB9 UniProtKB UniProtKB {GO:0002474=PMID:17977821, GO:0042288=GO_REF:0000033, GO:0042825=GO_REF:0000033, GO:0005886=GO_REF:0000033, GO:0005783=PMID:17977821, GO:0046980=GO_REF:0000033, GO:0005743=GO_REF:0000033, GO:0042626=GO_REF:0000002, GO:0030176=PMID:11011155, GO:0005765=PMID:17977821, GO:0015031=GO_REF:0000037, GO:0055085=GO_REF:0000033, GO:0005524=PMID:15863492, GO:0042803=PMID:18952056, GO:0015833=PMID:17977821, GO:0022891=PMID:18434309, GO:0001916=GO_REF:0000033, GO:0042605=GO_REF:0000033, GO:0016021=PMID:18434309, GO:0046978=GO_REF:0000033, GO:0015440=PMID:17977821, GO:0046979=GO_REF:0000033, GO:0005769=PMID:17977821, GO:0015421=GO_REF:0000033} Q9NP78 ATP-binding cassette sub-family B member 9 protein 20100212 {GO:0002474=IDA, GO:0042288=IBA, GO:0042825=IBA, GO:0005886=IBA, GO:0005783=IDA, GO:0046980=IBA, GO:0005743=IRD, GO:0042626=IEA, GO:0030176=IDA, GO:0005765=IDA, GO:0015031=IEA, GO:0055085=IBA, GO:0005524=IDA, GO:0042803=IPI, GO:0015833=IDA, GO:0022891=IDA, GO:0001916=IBA, GO:0042605=IBA, GO:0016021=IDA, GO:0046978=IBA, GO:0015440=IDA, GO:0046979=IBA, GO:0005769=IDA, GO:0015421=IBA} antigen processing and presentation of peptide antigen via MHC class I, peptide transport, positive regulation of T cell mediated cytotoxicity, protein transport, transmembrane transport TAP complex, early endosome, endoplasmic reticulum, integral to endoplasmic reticulum membrane, integral to membrane, lysosomal membrane, mitochondrial inner membrane, plasma membrane ATP binding, ATPase activity, coupled to transmembrane movement of substances, MHC class I protein binding, TAP1 binding, TAP2 binding, oligopeptide-transporting ATPase activity, peptide antigen binding, peptide-transporting ATPase activity, protein homodimerization activity, substrate-specific transmembrane transporter activity, tapasin binding Human UniProtKB:Q9NP78 ABCC1 GOC UniProtKB {GO:0019369=Reactome:REACT_147851, GO:0005215=PMID:1360704, GO:0005794=GO_REF:0000052, GO:0006200=PMID:15999530, GO:0005886=GO_REF:0000052, GO:0042493=PMID:1360704, GO:0005730=GO_REF:0000052, GO:0042626=GO_REF:0000002, GO:0005634=GO_REF:0000052, GO:0044281=Reactome:REACT_111217, GO:0055085=Reactome:REACT_15518, GO:0005524=GO_REF:0000037, GO:0006691=Reactome:REACT_150420, GO:0016020=PMID:1360704, GO:0005887=GO_REF:0000019, GO:0006810=PMID:1360704, GO:0016021=GO_REF:0000002, GO:0016887=PMID:15999530} P33527 Multidrug resistance-associated protein 1 protein 20130413 {GO:0019369=TAS, GO:0005215=TAS, GO:0005794=IDA, GO:0006200=IDA, GO:0005886=IDA, GO:0042493=TAS, GO:0005730=IDA, GO:0042626=IEA, GO:0005634=IDA, GO:0044281=TAS, GO:0055085=TAS, GO:0005524=IEA, GO:0006691=TAS, GO:0016020=TAS, GO:0005887=IEA, GO:0006810=TAS, GO:0016021=IEA, GO:0016887=IDA} ATP catabolic process, arachidonic acid metabolic process, leukotriene metabolic process, response to drug, small molecule metabolic process, transmembrane transport, transport Golgi apparatus, integral to membrane, integral to plasma membrane, membrane, nucleolus, nucleus, plasma membrane ATP binding, ATPase activity, ATPase activity, coupled to transmembrane movement of substances, transporter activity Human ABCC10 Reactome UniProtKB {GO:0005886=Reactome:REACT_111162, GO:0042626=GO_REF:0000002, GO:0016021=GO_REF:0000037, GO:0055085=Reactome:REACT_15518, GO:0016887=GO_REF:0000002, GO:0005524=GO_REF:0000037} Q5T3U5 Multidrug resistance-associated protein 7 protein 20130301 {GO:0005886=TAS, GO:0042626=IEA, GO:0016021=IEA, GO:0055085=TAS, GO:0016887=IEA, GO:0005524=IEA} transmembrane transport integral to membrane, plasma membrane ATP binding, ATPase activity, ATPase activity, coupled to transmembrane movement of substances Human ABCC12 ENSEMBL UniProtKB {GO:0005739=GO_REF:0000019, GO:0042626=GO_REF:0000002, GO:0016021=GO_REF:0000037, GO:0005524=GO_REF:0000037} Q96J65 Multidrug resistance-associated protein 9 protein 20130413 {GO:0005739=IEA, GO:0042626=IEA, GO:0016021=IEA, GO:0005524=IEA} integral to membrane, mitochondrion ATP binding, ATPase activity, coupled to transmembrane movement of substances Human Ensembl:ENSMUSP00000122402 ABCC2 GOC UniProtKB {GO:0005515=PMID:21988832, GO:0016324=GO_REF:0000024, GO:0046581=GO_REF:0000019, GO:0005886=Reactome:REACT_111162, GO:0005887=GO_REF:0000019, GO:0015711=PMID:7559771, GO:0006810=PMID:7559771, GO:0042626=GO_REF:0000002, GO:0008514=PMID:7559771, GO:0055085=Reactome:REACT_15518, GO:0005524=GO_REF:0000037} Q92887 Canalicular multispecific organic anion transporter 1 protein 20130413 {GO:0005515=IPI, GO:0016324=ISS, GO:0046581=IEA, GO:0005886=TAS, GO:0005887=IEA, GO:0015711=TAS, GO:0006810=TAS, GO:0042626=IEA, GO:0008514=TAS, GO:0055085=TAS, GO:0005524=IEA} organic anion transport, transmembrane transport, transport apical plasma membrane, integral to plasma membrane, intercellular canaliculus, plasma membrane ATP binding, ATPase activity, coupled to transmembrane movement of substances, organic anion transmembrane transporter activity, protein binding Human ABCC3 Reactome UniProtKB {GO:0005886=Reactome:REACT_111162, GO:0016020=PMID:9813153, GO:0005887=GO_REF:0000019, GO:0015721=Reactome:REACT_11042, GO:0006810=PMID:9813153, GO:0042626=GO_REF:0000002, GO:0008206=Reactome:REACT_11040, GO:0008514=PMID:9738950, GO:0044281=Reactome:REACT_111217, GO:0016021=GO_REF:0000002, GO:0055085=Reactome:REACT_15518, GO:0005524=GO_REF:0000037} O15438 Canalicular multispecific organic anion transporter 2 protein 20130301 {GO:0005886=TAS, GO:0016020=TAS, GO:0005887=IEA, GO:0015721=TAS, GO:0006810=TAS, GO:0042626=IEA, GO:0008206=TAS, GO:0008514=TAS, GO:0044281=TAS, GO:0016021=IEA, GO:0055085=TAS, GO:0005524=IEA} bile acid and bile salt transport, bile acid metabolic process, small molecule metabolic process, transmembrane transport, transport integral to membrane, integral to plasma membrane, membrane, plasma membrane ATP binding, ATPase activity, coupled to transmembrane movement of substances, organic anion transmembrane transporter activity Human ABCC4 UniProtKB UniProtKB {GO:0031088=Reactome:REACT_23865, GO:0008150=GO_REF:0000015, GO:0016020=PMID:15297306, GO:0005886=Reactome:REACT_111162, GO:0007596=Reactome:REACT_604, GO:0002576=Reactome:REACT_318, GO:0030168=Reactome:REACT_798, GO:0042626=GO_REF:0000002, GO:0016021=GO_REF:0000037, GO:0055085=Reactome:REACT_15518, GO:0005524=GO_REF:0000038, GO:0016404=PMID:7557451} Q8IUA3 Multidrug resistance-associated protein 4 protein 20130413 {GO:0031088=TAS, GO:0008150=ND, GO:0016020=IDA, GO:0005886=TAS, GO:0007596=TAS, GO:0002576=TAS, GO:0030168=TAS, GO:0042626=IEA, GO:0016021=IEA, GO:0055085=TAS, GO:0005524=IEA, GO:0016404=NAS} biological_process, blood coagulation, platelet activation, platelet degranulation, transmembrane transport integral to membrane, membrane, plasma membrane, platelet dense granule membrane 15-hydroxyprostaglandin dehydrogenase (NAD+) activity, ATP binding, ATPase activity, coupled to transmembrane movement of substances Human UniProtKB-KW:KW-0067 ABCC5 UniProtKB UniProtKB {GO:0005886=Reactome:REACT_121051, GO:0005975=Reactome:REACT_474, GO:0042626=GO_REF:0000002, GO:0044281=Reactome:REACT_111217, GO:0055085=Reactome:REACT_15518, GO:0005524=GO_REF:0000038, GO:0016020=PMID:15297306, GO:0005887=PMID:9827529, GO:0015711=PMID:9827529, GO:0006810=PMID:9827529, GO:0030213=Reactome:REACT_121301, GO:0030212=Reactome:REACT_121083, GO:0008514=PMID:9827529, GO:0016021=GO_REF:0000002, GO:0030203=Reactome:REACT_121315} Q86UX3 ATP-binding cassette C5 splicing variant A protein 20130413 {GO:0005886=TAS, GO:0005975=TAS, GO:0042626=IEA, GO:0044281=TAS, GO:0055085=TAS, GO:0005524=IEA, GO:0016020=IDA, GO:0005887=TAS, GO:0015711=TAS, GO:0006810=TAS, GO:0030213=TAS, GO:0030212=TAS, GO:0008514=TAS, GO:0016021=IEA, GO:0030203=TAS} carbohydrate metabolic process, glycosaminoglycan metabolic process, hyaluronan biosynthetic process, hyaluronan metabolic process, organic anion transport, small molecule metabolic process, transmembrane transport, transport integral to membrane, integral to plasma membrane, membrane, plasma membrane ATP binding, ATPase activity, coupled to transmembrane movement of substances, organic anion transmembrane transporter activity Human UniProtKB-KW:KW-0067 ABCC6 Reactome UniProtKB {GO:0005215=PMID:8912525, GO:0016324=GO_REF:0000019, GO:0005886=Reactome:REACT_111162, GO:0042493=PMID:8912525, GO:0006810=PMID:8912525, GO:0042626=GO_REF:0000002, GO:0016021=GO_REF:0000037, GO:0055085=Reactome:REACT_15518, GO:0016328=GO_REF:0000019, GO:0007601=GO_REF:0000037, GO:0005524=GO_REF:0000019} O95255 Multidrug resistance-associated protein 6 protein 20130301 {GO:0005215=TAS, GO:0016324=IEA, GO:0005886=TAS, GO:0042493=TAS, GO:0006810=TAS, GO:0042626=IEA, GO:0016021=IEA, GO:0055085=TAS, GO:0016328=IEA, GO:0007601=IEA, GO:0005524=IEA} response to drug, transmembrane transport, transport, visual perception apical plasma membrane, integral to membrane, lateral plasma membrane, plasma membrane ATP binding, ATPase activity, coupled to transmembrane movement of substances, transporter activity Human ABCC8 GOC UniProtKB {GO:0015079=PMID:7502040, GO:0005886=Reactome:REACT_111162, GO:0005975=PMID:7716548, GO:0008281=GO_REF:0000002, GO:0042626=GO_REF:0000002, GO:0007268=Reactome:REACT_13685, GO:0044281=Reactome:REACT_111217, GO:0005524=GO_REF:0000037, GO:0055085=Reactome:REACT_15518, GO:0044325=PMID:20610380, GO:0006112=Reactome:REACT_1505, GO:0050796=Reactome:REACT_18325, GO:0008076=PMID:20610380, GO:0016021=GO_REF:0000002, GO:0006813=PMID:7502040, GO:0071805=PMID:7502040} Q09428 ATP-binding cassette sub-family C member 8 protein 20130413 {GO:0015079=TAS, GO:0005886=TAS, GO:0005975=NAS, GO:0008281=IEA, GO:0042626=IEA, GO:0007268=TAS, GO:0044281=TAS, GO:0005524=IEA, GO:0055085=TAS, GO:0044325=IPI, GO:0006112=TAS, GO:0050796=TAS, GO:0008076=IDA, GO:0016021=IEA, GO:0006813=TAS, GO:0071805=TAS} carbohydrate metabolic process, energy reserve metabolic process, potassium ion transmembrane transport, potassium ion transport, regulation of insulin secretion, small molecule metabolic process, synaptic transmission, transmembrane transport integral to membrane, plasma membrane, voltage-gated potassium channel complex ATP binding, ATPase activity, coupled to transmembrane movement of substances, ion channel binding, potassium ion transmembrane transporter activity, sulfonylurea receptor activity Human ABCC9 InterPro UniProtKB {GO:0005215=PMID:8826984, GO:0005886=Reactome:REACT_111162, GO:0008282=GO_REF:0000024, GO:0008281=GO_REF:0000002, GO:0015459=GO_REF:0000024, GO:0010107=GO_REF:0000024, GO:0042626=GO_REF:0000002, GO:0007268=Reactome:REACT_13685, GO:0005524=GO_REF:0000002, GO:0030017=GO_REF:0000019, GO:0055085=Reactome:REACT_15518, GO:0044325=PMID:20610380, GO:0051607=PMID:18026101, GO:0016020=GO_REF:0000002, GO:0008076=PMID:20610380, GO:0016021=GO_REF:0000002, GO:0006813=GO_REF:0000002} Q8N4N7 ATP-binding cassette sub-family C member 9 protein 20130413 {GO:0005215=TAS, GO:0005886=TAS, GO:0008282=ISS, GO:0008281=IEA, GO:0015459=ISS, GO:0010107=ISS, GO:0042626=IEA, GO:0007268=TAS, GO:0005524=IEA, GO:0030017=IEA, GO:0055085=TAS, GO:0044325=IPI, GO:0051607=IMP, GO:0016020=IEA, GO:0008076=IDA, GO:0016021=IEA, GO:0006813=IEA} defense response to virus, potassium ion import, potassium ion transport, synaptic transmission, transmembrane transport ATP-sensitive potassium channel complex, integral to membrane, membrane, plasma membrane, sarcomere, voltage-gated potassium channel complex ATP binding, ATPase activity, coupled to transmembrane movement of substances, ion channel binding, potassium channel regulator activity, sulfonylurea receptor activity, transporter activity Human InterPro:IPR000388 ABCD1 GOC UniProtKB {GO:0005515=PMID:10551832, GO:0005215=PMID:8441467, GO:0006200=PMID:11248239, GO:0042626=PMID:8441467, GO:0044281=Reactome:REACT_111217, GO:0042803=PMID:17609205, GO:0042802=PMID:10551832, GO:0005829=Reactome:REACT_15396, GO:0005739=GO_REF:0000019, GO:0015910=PMID:18757502, GO:0006810=GO_REF:0000002, GO:0007031=PMID:8441467, GO:0015919=PMID:8441467, GO:0016887=PMID:11248239, GO:0005779=PMID:8441467, GO:0044255=Reactome:REACT_16957, GO:0042760=PMID:9425230, GO:0005778=Reactome:REACT_121197, GO:0005777=PMID:10777694, GO:0006635=PMID:21145416, GO:0005325=Reactome:REACT_16917, GO:0036109=Reactome:REACT_121147, GO:0055085=Reactome:REACT_15518, GO:0005524=PMID:11248239, GO:0033559=Reactome:REACT_121284, GO:0043651=Reactome:REACT_121100, GO:0016020=GO_REF:0000002, GO:0042758=PMID:18757502, GO:0033540=Reactome:REACT_17062, GO:0019899=PMID:16781659} P33897 ATP-binding cassette sub-family D member 1 protein 20130413 {GO:0005515=IPI, GO:0005215=NAS, GO:0006200=IDA, GO:0042626=NAS, GO:0044281=TAS, GO:0042803=IDA, GO:0042802=IPI, GO:0005829=TAS, GO:0005739=IEA, GO:0015910=IGI, GO:0006810=IEA, GO:0007031=NAS, GO:0015919=NAS, GO:0016887=IDA, GO:0005779=NAS, GO:0044255=TAS, GO:0042760=IDA, GO:0005778=TAS, GO:0005777=IDA, GO:0006635=IGI, GO:0005325=TAS, GO:0036109=TAS, GO:0055085=TAS, GO:0005524=IDA, GO:0033559=TAS, GO:0043651=TAS, GO:0016020=IEA, GO:0042758=IGI, GO:0033540=TAS, GO:0019899=IPI} ATP catabolic process, alpha-linolenic acid metabolic process, cellular lipid metabolic process, fatty acid beta-oxidation, fatty acid beta-oxidation using acyl-CoA oxidase, linoleic acid metabolic process, long-chain fatty acid catabolic process, peroxisomal long-chain fatty acid import, peroxisomal membrane transport, peroxisome organization, small molecule metabolic process, transmembrane transport, transport, unsaturated fatty acid metabolic process, very long-chain fatty acid catabolic process cytosol, integral to peroxisomal membrane, membrane, mitochondrion, peroxisomal membrane, peroxisome ATP binding, ATPase activity, ATPase activity, coupled to transmembrane movement of substances, enzyme binding, identical protein binding, peroxisomal fatty-acyl-CoA transporter activity, protein binding, protein homodimerization activity, transporter activity Human ABCD2 HPA UniProtKB {GO:0005515=PMID:10777694, GO:0006635=PMID:21145416, GO:0005524=GO_REF:0000037, GO:0055085=Reactome:REACT_15518, GO:0042803=PMID:21145416, GO:0043231=GO_REF:0000052, GO:0005829=Reactome:REACT_15396, GO:0005739=GO_REF:0000019, GO:0032000=PMID:10196381, GO:0016021=GO_REF:0000037, GO:0016887=GO_REF:0000002, GO:0042760=PMID:21145416, GO:0005778=Reactome:REACT_15396, GO:0005777=PMID:21145416} Q9UBJ2 ATP-binding cassette sub-family D member 2 protein 20110516 {GO:0005515=IPI, GO:0006635=IGI, GO:0005524=IEA, GO:0055085=TAS, GO:0042803=IDA, GO:0043231=IDA, GO:0005829=TAS, GO:0005739=IEA, GO:0032000=IDA, GO:0016021=IEA, GO:0016887=IEA, GO:0042760=IGI, GO:0005778=TAS, GO:0005777=IDA} fatty acid beta-oxidation, positive regulation of fatty acid beta-oxidation, transmembrane transport, very long-chain fatty acid catabolic process cytosol, integral to membrane, intracellular membrane-bounded organelle, mitochondrion, peroxisomal membrane, peroxisome ATP binding, ATPase activity, protein binding, protein homodimerization activity Human ABCD3 GOC UniProtKB {GO:0005515=PMID:14709540, GO:0006200=PMID:11248239, GO:0005782=PMID:9765053, GO:0005743=GO_REF:0000019, GO:0042626=GO_REF:0000002, GO:0055085=Reactome:REACT_15518, GO:0005524=PMID:11248239, GO:0042803=PMID:17609205, GO:0005829=Reactome:REACT_15396, GO:0043231=GO_REF:0000052, GO:0006810=GO_REF:0000002, GO:0007031=PMID:9765053, GO:0016021=GO_REF:0000037, GO:0016887=PMID:11248239, GO:0042760=PMID:9425230, GO:0005778=Reactome:REACT_15396, GO:0005777=PMID:9922452} P28288 ATP-binding cassette sub-family D member 3 protein 20130413 {GO:0005515=IPI, GO:0006200=IDA, GO:0005782=IDA, GO:0005743=IEA, GO:0042626=IEA, GO:0055085=TAS, GO:0005524=IDA, GO:0042803=IDA, GO:0005829=TAS, GO:0043231=IDA, GO:0006810=IEA, GO:0007031=IMP, GO:0016021=IEA, GO:0016887=IDA, GO:0042760=IGI, GO:0005778=TAS, GO:0005777=IDA} ATP catabolic process, peroxisome organization, transmembrane transport, transport, very long-chain fatty acid catabolic process cytosol, integral to membrane, intracellular membrane-bounded organelle, mitochondrial inner membrane, peroxisomal matrix, peroxisomal membrane, peroxisome ATP binding, ATPase activity, ATPase activity, coupled to transmembrane movement of substances, protein binding, protein homodimerization activity Human ABCD4 UniProtKB UniProtKB {GO:0009235=PMID:22922874, GO:0016020=GO_REF:0000002, GO:0005789=GO_REF:0000019, GO:0006810=GO_REF:0000002, GO:0042626=PMID:9266848, GO:0016021=PMID:9266848, GO:0043190=PMID:9266848, GO:0055085=PMID:9266848, GO:0005524=PMID:9266848, GO:0016887=GO_REF:0000002, GO:0005778=GO_REF:0000039, GO:0005777=PMID:14533738} O14678 ATP-binding cassette sub-family D member 4 protein 20120426 {GO:0009235=IMP, GO:0016020=IEA, GO:0005789=IEA, GO:0006810=IEA, GO:0042626=NAS, GO:0016021=NAS, GO:0043190=NAS, GO:0055085=NAS, GO:0005524=NAS, GO:0016887=IEA, GO:0005778=IEA, GO:0005777=IDA} cobalamin metabolic process, transmembrane transport, transport ATP-binding cassette (ABC) transporter complex, endoplasmic reticulum membrane, integral to membrane, membrane, peroxisomal membrane, peroxisome ATP binding, ATPase activity, ATPase activity, coupled to transmembrane movement of substances Human ABCE1 PINC UniProtKB {GO:0005739=PMID:11585831, GO:0005737=PMID:11585831, GO:0051539=GO_REF:0000038, GO:0008428=PMID:7539425, GO:0051536=GO_REF:0000002, GO:0019048=GO_REF:0000037, GO:0009055=GO_REF:0000002, GO:0009615=PMID:7539425, GO:0005524=GO_REF:0000037, GO:0016887=GO_REF:0000002, GO:0046872=GO_REF:0000038, GO:0006401=PMID:7539425} P61221 ATP-binding cassette sub-family E member 1 protein 20061116 {GO:0005739=IDA, GO:0005737=IDA, GO:0051539=IEA, GO:0008428=TAS, GO:0051536=IEA, GO:0019048=IEA, GO:0009055=IEA, GO:0009615=TAS, GO:0005524=IEA, GO:0016887=IEA, GO:0046872=IEA, GO:0006401=TAS} RNA catabolic process, response to virus, virus-host interaction cytoplasm, mitochondrion 4 iron, 4 sulfur cluster binding, ATP binding, ATPase activity, electron carrier activity, iron-sulfur cluster binding, metal ion binding, ribonuclease inhibitor activity Human ABCF1 PINC UniProtKB {GO:0005515=PMID:17894550, GO:0006954=PMID:9790762, GO:0005840=GO_REF:0000019, GO:0005654=GO_REF:0000039, GO:0005635=GO_REF:0000039, GO:0006412=PMID:9790762, GO:0005524=GO_REF:0000037, GO:0016887=GO_REF:0000002, GO:0008135=PMID:9790762} Q8NE71 ATP-binding cassette sub-family F member 1 protein 20050308 {GO:0005515=IPI, GO:0006954=TAS, GO:0005840=IEA, GO:0005654=IEA, GO:0005635=IEA, GO:0006412=TAS, GO:0005524=IEA, GO:0016887=IEA, GO:0008135=TAS} inflammatory response, translation nuclear envelope, nucleoplasm, ribosome ATP binding, ATPase activity, protein binding, translation factor activity, nucleic acid binding Human ABCF2 PINC UniProtKB {GO:0005739=GO_REF:0000019, GO:0005215=PMID:9878413, GO:0006810=PMID:9878413, GO:0005740=PMID:9878413, GO:0043190=PMID:9878413, GO:0016887=GO_REF:0000002, GO:0005524=GO_REF:0000037} Q9UG63 ATP-binding cassette sub-family F member 2 protein 20030904 {GO:0005739=IEA, GO:0005215=TAS, GO:0006810=TAS, GO:0005740=TAS, GO:0043190=TAS, GO:0016887=IEA, GO:0005524=IEA} transport ATP-binding cassette (ABC) transporter complex, mitochondrial envelope, mitochondrion ATP binding, ATPase activity, transporter activity Human ABCF3 UniProtKB UniProtKB {GO:0051607=GO_REF:0000037, GO:0005524=GO_REF:0000037, GO:0016887=GO_REF:0000002} Q9NUQ8 ATP-binding cassette sub-family F member 3 protein 20130413 {GO:0051607=IEA, GO:0005524=IEA, GO:0016887=IEA} defense response to virus ATP binding, ATPase activity Human UniProtKB-KW:KW-0051 ABCG1 GOC UniProtKB {GO:0019534=PMID:17408620, GO:0042803=PMID:16870176, GO:0046983=PMID:11500512, GO:0006810=GO_REF:0000002, GO:0042632=PMID:15994327, GO:0033344=PMID:15994327, GO:0005794=PMID:16780588, GO:0046982=PMID:16870176, GO:0010745=PMID:18490524, GO:0043691=GO_REF:0000024, GO:0005548=PMID:16702602, GO:0055099=GO_REF:0000019, GO:0043531=PMID:16702602, GO:0034374=PMID:16556852, GO:0005887=PMID:11500512, GO:0034375=PMID:16556852, GO:0042157=Reactome:REACT_13621, GO:0005789=GO_REF:0000039, GO:0055091=PMID:16702602, GO:0034436=PMID:17293612, GO:0034437=PMID:17293612, GO:0045542=GO_REF:0000024, GO:0032367=PMID:15994327, GO:0009897=PMID:16556852, GO:0006629=Reactome:REACT_602, GO:0005886=Reactome:REACT_13681, GO:0017127=PMID:15994327, GO:0033993=PMID:16556852, GO:0010872=PMID:16556852, GO:0044281=Reactome:REACT_111217, GO:0010875=GO_REF:0000019, GO:0005739=PMID:22042635, GO:0005543=PMID:16702602, GO:0015485=PMID:15994327, GO:0016887=GO_REF:0000002, GO:1901998=PMID:17408620, GO:0009720=PMID:11500512, GO:0008203=PMID:15994327, GO:0042987=PMID:17293612, GO:0006355=GO_REF:0000024, GO:0010033=PMID:11500512, GO:0055085=Reactome:REACT_15518, GO:0005524=PMID:16702602, GO:0010887=PMID:18490524, GO:0033700=PMID:16702602, GO:0000139=GO_REF:0000039, GO:0034041=PMID:17408620, GO:0016021=GO_REF:0000002, GO:0055037=PMID:16556852, GO:0005768=GO_REF:0000024} P45844 ATP-binding cassette sub-family G member 1 protein 20130413 {GO:0019534=IDA, GO:0042803=IDA, GO:0046983=NAS, GO:0006810=IEA, GO:0042632=IDA, GO:0033344=IDA, GO:0005794=IDA, GO:0046982=IPI, GO:0010745=TAS, GO:0043691=ISS, GO:0005548=IDA, GO:0055099=IEA, GO:0043531=IDA, GO:0034374=ISS, GO:0005887=IC, GO:0034375=ISS, GO:0042157=TAS, GO:0005789=IEA, GO:0055091=IMP, GO:0034436=IDA, GO:0034437=IDA, GO:0045542=ISS, GO:0032367=IMP, GO:0009897=IDA, GO:0006629=TAS, GO:0005886=TAS, GO:0017127=IDA, GO:0033993=IDA, GO:0010872=ISS, GO:0044281=TAS, GO:0010875=IEA, GO:0005739=IDA, GO:0005543=IC, GO:0015485=IC, GO:0016887=IEA, GO:1901998=IDA, GO:0009720=NAS, GO:0008203=IDA, GO:0042987=IDA, GO:0006355=ISS, GO:0010033=IDA, GO:0055085=TAS, GO:0005524=IDA, GO:0010887=TAS, GO:0033700=IMP, GO:0000139=IEA, GO:0034041=IDA, GO:0016021=IEA, GO:0055037=ISS, GO:0005768=ISS} amyloid precursor protein catabolic process, cholesterol efflux, cholesterol homeostasis, cholesterol metabolic process, detection of hormone stimulus, glycoprotein transport, high-density lipoprotein particle remodeling, intracellular cholesterol transport, lipid metabolic process, lipoprotein metabolic process, low-density lipoprotein particle remodeling, negative regulation of cholesterol storage, negative regulation of macrophage derived foam cell differentiation, phospholipid efflux, phospholipid homeostasis, positive regulation of cholesterol biosynthetic process, positive regulation of cholesterol efflux, regulation of cholesterol esterification, regulation of transcription, DNA-dependent, response to high density lipoprotein particle stimulus, response to lipid, response to organic substance, reverse cholesterol transport, small molecule metabolic process, toxin transport, transmembrane transport, transport Golgi apparatus, Golgi membrane, endoplasmic reticulum membrane, endosome, external side of plasma membrane, integral to membrane, integral to plasma membrane, mitochondrion, plasma membrane, recycling endosome ADP binding, ATP binding, ATPase activity, cholesterol binding, cholesterol transporter activity, glycoprotein transporter activity, phospholipid binding, phospholipid transporter activity, protein dimerization activity, protein heterodimerization activity, protein homodimerization activity, sterol-transporting ATPase activity, toxin transporter activity Human ABCG2 GOC UniProtKB {GO:0015886=Reactome:REACT_25155, GO:0005215=PMID:9861027, GO:0005886=Reactome:REACT_25155, GO:0015232=Reactome:REACT_25155, GO:0042493=PMID:9861027, GO:0042626=PMID:9850061, GO:0044281=Reactome:REACT_111217, GO:0046415=PMID:19503597, GO:0055085=Reactome:REACT_15518, GO:0005524=GO_REF:0000037, GO:0042803=PMID:16870176, GO:0006879=Reactome:REACT_25060, GO:0008559=PMID:9861027, GO:0006855=Reactome:REACT_120801, GO:0006810=PMID:9850061, GO:0016021=GO_REF:0000037} Q9UNQ0 ATP-binding cassette sub-family G member 2 protein 20130413 {GO:0015886=TAS, GO:0005215=TAS, GO:0005886=TAS, GO:0015232=TAS, GO:0042493=TAS, GO:0042626=TAS, GO:0044281=TAS, GO:0046415=IMP, GO:0055085=TAS, GO:0005524=IEA, GO:0042803=IDA, GO:0006879=TAS, GO:0008559=TAS, GO:0006855=TAS, GO:0006810=TAS, GO:0016021=IEA} cellular iron ion homeostasis, drug transmembrane transport, heme transport, response to drug, small molecule metabolic process, transmembrane transport, transport, urate metabolic process integral to membrane, plasma membrane ATP binding, ATPase activity, coupled to transmembrane movement of substances, heme transporter activity, protein homodimerization activity, transporter activity, xenobiotic-transporting ATPase activity Human ABCG4 BHF-UCL UniProtKB {GO:0033344=PMID:16682745, GO:0046982=PMID:16870176, GO:0005886=Reactome:REACT_111034, GO:0017127=Reactome:REACT_111034, GO:0016021=GO_REF:0000037, GO:0055085=Reactome:REACT_15518, GO:0016887=GO_REF:0000002, GO:0005524=GO_REF:0000037, GO:0042803=PMID:16870176} Q9H172 ATP-binding cassette sub-family G member 4 protein 20090507 {GO:0033344=TAS, GO:0046982=IPI, GO:0005886=TAS, GO:0017127=TAS, GO:0016021=IEA, GO:0055085=TAS, GO:0016887=IEA, GO:0005524=IEA, GO:0042803=IDA} cholesterol efflux, transmembrane transport integral to membrane, plasma membrane ATP binding, ATPase activity, cholesterol transporter activity, protein heterodimerization activity, protein homodimerization activity Human ABCG5 GOC UniProtKB {GO:0042632=PMID:11099417, GO:0005515=PMID:17474147, GO:0006629=Reactome:REACT_602, GO:0007588=PMID:14504269, GO:0033344=PMID:14504269, GO:0006200=PMID:16893193, GO:0046982=PMID:16870176, GO:0005886=Reactome:REACT_13440, GO:0007584=GO_REF:0000019, GO:0042493=GO_REF:0000019, GO:0017127=PMID:14504269, GO:0044281=Reactome:REACT_111217, GO:0045796=PMID:11099417, GO:0055085=Reactome:REACT_15518, GO:0005524=PMID:16893193, GO:0030299=PMID:12208868, GO:0016324=PMID:14504269, GO:0016020=GO_REF:0000002, GO:0010949=PMID:11099417, GO:0010212=GO_REF:0000019, GO:0015918=Reactome:REACT_13781, GO:0016021=GO_REF:0000037, GO:0016887=PMID:16893193} Q9H222 ATP-binding cassette sub-family G member 5 protein 20130413 {GO:0042632=IMP, GO:0005515=IPI, GO:0006629=TAS, GO:0007588=IGI, GO:0033344=IGI, GO:0006200=IDA, GO:0046982=IPI, GO:0005886=TAS, GO:0007584=IEA, GO:0042493=IEA, GO:0017127=IGI, GO:0044281=TAS, GO:0045796=IMP, GO:0055085=TAS, GO:0005524=IDA, GO:0030299=IC, GO:0016324=IMP, GO:0016020=IEA, GO:0010949=IMP, GO:0010212=IEA, GO:0015918=TAS, GO:0016021=IEA, GO:0016887=IDA} ATP catabolic process, cholesterol efflux, cholesterol homeostasis, excretion, intestinal cholesterol absorption, lipid metabolic process, negative regulation of intestinal cholesterol absorption, negative regulation of intestinal phytosterol absorption, response to drug, response to ionizing radiation, response to nutrient, small molecule metabolic process, sterol transport, transmembrane transport apical plasma membrane, integral to membrane, membrane, plasma membrane ATP binding, ATPase activity, cholesterol transporter activity, protein binding, protein heterodimerization activity Human ABCG8 GOC UniProtKB {GO:0006629=Reactome:REACT_602, GO:0042632=PMID:11099417, GO:0007588=PMID:14504269, GO:0033344=PMID:14504269, GO:0006200=PMID:16893193, GO:0005886=Reactome:REACT_13440, GO:0046982=PMID:16870176, GO:0007584=GO_REF:0000019, GO:0042493=GO_REF:0000019, GO:0017127=PMID:14504269, GO:0044281=Reactome:REACT_111217, GO:0055085=Reactome:REACT_15518, GO:0045796=PMID:11099417, GO:0005524=PMID:16893193, GO:0030299=PMID:12208868, GO:0016324=PMID:14504269, GO:0015914=GO_REF:0000019, GO:0010949=PMID:11099417, GO:0015918=Reactome:REACT_13781, GO:0016021=GO_REF:0000037, GO:0016887=PMID:16893193} Q9H221 ATP-binding cassette sub-family G member 8 protein 20130413 {GO:0006629=TAS, GO:0042632=IMP, GO:0007588=IGI, GO:0033344=IGI, GO:0006200=IDA, GO:0005886=TAS, GO:0046982=IPI, GO:0007584=IEA, GO:0042493=IEA, GO:0017127=IGI, GO:0044281=TAS, GO:0055085=TAS, GO:0045796=IMP, GO:0005524=IDA, GO:0030299=IC, GO:0016324=IMP, GO:0015914=IEA, GO:0010949=IMP, GO:0015918=TAS, GO:0016021=IEA, GO:0016887=IDA} ATP catabolic process, cholesterol efflux, cholesterol homeostasis, excretion, intestinal cholesterol absorption, lipid metabolic process, negative regulation of intestinal cholesterol absorption, negative regulation of intestinal phytosterol absorption, phospholipid transport, response to drug, response to nutrient, small molecule metabolic process, sterol transport, transmembrane transport apical plasma membrane, integral to membrane, plasma membrane ATP binding, ATPase activity, cholesterol transporter activity, protein heterodimerization activity Human ABHD10 BHF-UCL UniProtKB {GO:0005739=GO_REF:0000054, GO:0016787=GO_REF:0000038, GO:0005829=PMID:22294686} Q9NUJ1 Mycophenolic acid acyl-glucuronide esterase, mitochondrial protein 20120510 {GO:0005739=IDA, GO:0016787=IEA, GO:0005829=IDA} cytosol, mitochondrion hydrolase activity Human ABHD11 UniProtKB UniProtKB {GO:0005739=GO_REF:0000019, GO:0008150=GO_REF:0000015, GO:0003674=GO_REF:0000015, GO:0016787=GO_REF:0000037, GO:0005575=GO_REF:0000015} Q8NFV4 Alpha/beta hydrolase domain-containing protein 11 protein 20080407 {GO:0005739=IEA, GO:0008150=ND, GO:0003674=ND, GO:0016787=IEA, GO:0005575=ND} biological_process cellular_component, mitochondrion hydrolase activity, molecular_function Human ABHD12 UniProtKB UniProtKB {GO:0047372=GO_REF:0000003, GO:0016021=GO_REF:0000037} Q8N2K0 Monoacylglycerol lipase ABHD12 protein 20130413 {GO:0047372=IEA, GO:0016021=IEA} integral to membrane acylglycerol lipase activity Human EC:3.1.1.23 ABHD14A UniProtKB UniProtKB {GO:0005737=GO_REF:0000039, GO:0016787=GO_REF:0000037, GO:0016021=GO_REF:0000037} Q9BUJ0 Alpha/beta hydrolase domain-containing protein 14A protein 20130413 {GO:0005737=IEA, GO:0016787=IEA, GO:0016021=IEA} cytoplasm, integral to membrane hydrolase activity Human UniProtKB-SubCell:SL-0086 ABHD14B HPA UniProtKB {GO:0005737=GO_REF:0000052, GO:0016787=GO_REF:0000037, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052} Q96IU4 Alpha/beta hydrolase domain-containing protein 14B protein 20110516 {GO:0005737=IDA, GO:0016787=IEA, GO:0005730=IDA, GO:0005634=IDA} cytoplasm, nucleolus, nucleus hydrolase activity Human ABHD16A UniProtKB UniProtKB {GO:0016787=GO_REF:0000037, GO:0016021=GO_REF:0000037} O95870 Abhydrolase domain-containing protein 16A protein 20130413 {GO:0016787=IEA, GO:0016021=IEA} integral to membrane hydrolase activity Human UniProtKB-KW:KW-0378 ABHD2 UniProtKB UniProtKB {GO:0004091=GO_REF:0000037, GO:0003674=GO_REF:0000015, GO:0008150=GO_REF:0000015, GO:0030336=GO_REF:0000019, GO:0009611=GO_REF:0000019, GO:0016021=GO_REF:0000029} P08910 Abhydrolase domain-containing protein 2 protein 20060502 {GO:0004091=IEA, GO:0003674=ND, GO:0008150=ND, GO:0030336=IEA, GO:0009611=IEA, GO:0016021=NAS} biological_process, negative regulation of cell migration, response to wounding integral to membrane carboxylesterase activity, molecular_function Human ABHD3 UniProtKB UniProtKB {GO:0004091=GO_REF:0000037, GO:0008150=GO_REF:0000015, GO:0003674=GO_REF:0000015, GO:0016787=GO_REF:0000038, GO:0005575=GO_REF:0000015, GO:0016021=GO_REF:0000037} Q8WU67 Abhydrolase domain-containing protein 3 protein 20080407 {GO:0004091=IEA, GO:0008150=ND, GO:0003674=ND, GO:0016787=IEA, GO:0005575=ND, GO:0016021=IEA} biological_process cellular_component, integral to membrane carboxylesterase activity, hydrolase activity, molecular_function Human ABHD4 UniProtKB UniProtKB {GO:0016042=GO_REF:0000037, GO:0016787=GO_REF:0000037} Q8TB40 Abhydrolase domain-containing protein 4 protein 20130413 {GO:0016042=IEA, GO:0016787=IEA} lipid catabolic process hydrolase activity Human UniProtKB-KW:KW-0378 ABHD5 Reactome UniProtKB {GO:0005811=GO_REF:0000024, GO:0006629=Reactome:REACT_602, GO:0042171=PMID:18606822, GO:0004806=GO_REF:0000024, GO:0010898=PMID:16679289, GO:0044281=Reactome:REACT_111217, GO:0003841=GO_REF:0000003, GO:0030154=GO_REF:0000037, GO:0005829=GO_REF:0000024, GO:0010891=PMID:16679289, GO:0006508=GO_REF:0000002, GO:0006631=GO_REF:0000037, GO:0008233=GO_REF:0000002, GO:0019433=Reactome:REACT_494, GO:0006654=PMID:18606822, GO:0051006=GO_REF:0000019} Q8WTS1 1-acylglycerol-3-phosphate O-acyltransferase ABHD5 protein 20130213 {GO:0005811=ISS, GO:0006629=TAS, GO:0042171=IDA, GO:0004806=ISS, GO:0010898=IDA, GO:0044281=TAS, GO:0003841=IEA, GO:0030154=IEA, GO:0005829=ISS, GO:0010891=IDA, GO:0006508=IEA, GO:0006631=IEA, GO:0008233=IEA, GO:0019433=TAS, GO:0006654=IDA, GO:0051006=IEA} cell differentiation, fatty acid metabolic process, lipid metabolic process, negative regulation of sequestering of triglyceride, phosphatidic acid biosynthetic process, positive regulation of lipoprotein lipase activity, positive regulation of triglyceride catabolic process, proteolysis, small molecule metabolic process, triglyceride catabolic process cytosol, lipid particle 1-acylglycerol-3-phosphate O-acyltransferase activity, lysophosphatidic acid acyltransferase activity, peptidase activity, triglyceride lipase activity Human ABHD6 ENSEMBL UniProtKB {GO:0005739=GO_REF:0000019, GO:0030336=GO_REF:0000019, GO:0047372=GO_REF:0000003, GO:0016021=GO_REF:0000037, GO:0060292=GO_REF:0000019, GO:2000124=GO_REF:0000019} Q9BV23 Monoacylglycerol lipase ABHD6 protein 20130413 {GO:0005739=IEA, GO:0030336=IEA, GO:0047372=IEA, GO:0016021=IEA, GO:0060292=IEA, GO:2000124=IEA} long term synaptic depression, negative regulation of cell migration, regulation of endocannabinoid signaling pathway integral to membrane, mitochondrion acylglycerol lipase activity Human Ensembl:ENSMUSP00000129169 ABHD8 UniProtKB UniProtKB {GO:0016787=GO_REF:0000037} Q96I13 Abhydrolase domain-containing protein 8 protein 20130413 {GO:0016787=IEA} hydrolase activity Human UniProtKB-KW:KW-0378 ABI1 IntAct UniProtKB {GO:0008092=PMID:9593709, GO:0005515=PMID:21078624, GO:0008285=PMID:9010225, GO:0030054=GO_REF:0000037, GO:0005783=PMID:9593709, GO:0001756=GO_REF:0000019, GO:0045202=GO_REF:0000037, GO:0006928=PMID:11516653, GO:0018108=PMID:17101133, GO:0005634=GO_REF:0000039, GO:0030175=PMID:11516653, GO:0030027=PMID:17101133, GO:0005829=Reactome:REACT_160291, GO:0030426=GO_REF:0000039, GO:0005622=PMID:17101133, GO:0005737=GO_REF:0000002, GO:0030296=GO_REF:0000019, GO:0008154=PMID:11516653, GO:0045087=Reactome:REACT_6802, GO:0005856=GO_REF:0000039, GO:0038096=Reactome:REACT_160123, GO:0007169=PMID:9010225} Q8IZP0 Abl interactor 1 protein 20130415 {GO:0008092=TAS, GO:0005515=IPI, GO:0008285=TAS, GO:0030054=IEA, GO:0005783=TAS, GO:0001756=IEA, GO:0045202=IEA, GO:0006928=IDA, GO:0018108=IDA, GO:0005634=IEA, GO:0030175=IDA, GO:0030027=IDA, GO:0005829=TAS, GO:0030426=IEA, GO:0005622=IDA, GO:0005737=IEA, GO:0030296=IEA, GO:0008154=NAS, GO:0045087=TAS, GO:0005856=IEA, GO:0038096=TAS, GO:0007169=TAS} Fc-gamma receptor signaling pathway involved in phagocytosis, actin polymerization or depolymerization, cellular component movement, innate immune response, negative regulation of cell proliferation, peptidyl-tyrosine phosphorylation, somitogenesis, transmembrane receptor protein tyrosine kinase signaling pathway cell junction, cytoplasm, cytoskeleton, cytosol, endoplasmic reticulum, filopodium, growth cone, intracellular, lamellipodium, nucleus, synapse cytoskeletal protein binding, protein binding, protein tyrosine kinase activator activity Human UniProtKB:O00555 ABI2 BHF-UCL UniProtKB {GO:0017124=PMID:7590236, GO:0006928=PMID:11516653, GO:0018108=PMID:17101133, GO:0030175=PMID:11516653, GO:0003677=PMID:7590236, GO:0030027=PMID:11516653, GO:0016358=GO_REF:0000019, GO:0030425=GO_REF:0000019, GO:0005829=PMID:18632609, GO:0005737=PMID:8649853, GO:0005913=GO_REF:0000019, GO:0016477=PMID:12011975, GO:0008154=PMID:11516653, GO:0007010=PMID:12011975, GO:0007611=GO_REF:0000019, GO:0043010=GO_REF:0000019, GO:0005856=GO_REF:0000039, GO:0019900=PMID:8649853, GO:0070064=PMID:7590236, GO:0031625=PMID:18632609, GO:0008093=PMID:12011975} Q9NYB9 Abl interactor 2 protein 20110401 {GO:0017124=IPI, GO:0006928=IDA, GO:0018108=IDA, GO:0030175=IDA, GO:0003677=TAS, GO:0030027=IDA, GO:0016358=IEA, GO:0030425=IEA, GO:0005829=IDA, GO:0005737=TAS, GO:0005913=IEA, GO:0016477=TAS, GO:0008154=NAS, GO:0007010=TAS, GO:0007611=IEA, GO:0043010=IEA, GO:0005856=IEA, GO:0019900=NAS, GO:0070064=IPI, GO:0031625=IPI, GO:0008093=TAS} actin polymerization or depolymerization, camera-type eye development, cell migration, cellular component movement, cytoskeleton organization, dendrite development, learning or memory, peptidyl-tyrosine phosphorylation cell-cell adherens junction, cytoplasm, cytoskeleton, cytosol, dendrite, filopodium, lamellipodium DNA binding, SH3 domain binding, cytoskeletal adaptor activity, kinase binding, proline-rich region binding, ubiquitin protein ligase binding Human ABI3 IntAct UniProtKB {GO:0005515=PMID:19060904, GO:0030334=PMID:11956071, GO:0005622=PMID:17101133, GO:0005737=GO_REF:0000054, GO:0006928=PMID:11956071, GO:0018108=PMID:17101133, GO:0030027=PMID:17101133} Q9P2A4 ABI gene family member 3 protein 20130415 {GO:0005515=IPI, GO:0030334=IDA, GO:0005622=IDA, GO:0005737=IDA, GO:0006928=NAS, GO:0018108=IDA, GO:0030027=IDA} cellular component movement, peptidyl-tyrosine phosphorylation, regulation of cell migration cytoplasm, intracellular, lamellipodium protein binding Human UniProtKB:O15372 ABI3BP ENSEMBL UniProtKB {GO:0030198=GO_REF:0000019, GO:0010811=GO_REF:0000019, GO:0005518=GO_REF:0000019, GO:0005614=GO_REF:0000019, GO:0008201=GO_REF:0000019} Q7Z7G0 Target of Nesh-SH3 protein 20130413 {GO:0030198=IEA, GO:0010811=IEA, GO:0005518=IEA, GO:0005614=IEA, GO:0008201=IEA} extracellular matrix organization, positive regulation of cell-substrate adhesion interstitial matrix collagen binding, heparin binding Human Ensembl:ENSMUSP00000036257 ABL1 HPA UniProtKB {GO:0005515=PMID:12893824, GO:0051353=PMID:12893824, GO:2001020=PMID:9461559, GO:2000145=PMID:20841568, GO:0050731=PMID:15657060, GO:0030155=PMID:20841568, GO:0042692=Reactome:REACT_21303, GO:2000249=PMID:20841568, GO:0030100=PMID:20841568, GO:0007411=Reactome:REACT_18266, GO:0006298=PMID:10391249, GO:0070064=PMID:15657060, GO:0051019=PMID:11121037, GO:0031965=GO_REF:0000039, GO:0000287=PMID:9144171, GO:0018108=PMID:11121037, GO:0042770=PMID:15657060, GO:0051149=Reactome:REACT_21402, GO:0000115=PMID:8242749, GO:0045087=Reactome:REACT_6802, GO:0004515=PMID:20841568, GO:0010506=PMID:20841568, GO:0038096=Reactome:REACT_160123, GO:0017124=PMID:7590236, GO:0048471=PMID:17888034, GO:0030036=GO_REF:0000024, GO:0071901=PMID:11121037, GO:0005634=GO_REF:0000052, GO:0015629=PMID:20841568, GO:0005829=Reactome:REACT_160185, GO:0005739=GO_REF:0000039, GO:0005737=PMID:20841568, GO:0051726=GO_REF:0000019, GO:0007155=GO_REF:0000037, GO:0031252=GO_REF:0000019, GO:0006355=PMID:8242749, GO:0043065=PMID:9037071, GO:0030145=PMID:9144171, GO:0008630=PMID:20841568, GO:0006914=GO_REF:0000037, GO:0005730=GO_REF:0000052, GO:0008022=PMID:11971963, GO:0005524=PMID:9144171, GO:0003677=PMID:8242749, GO:0006974=PMID:15657060, GO:0006975=PMID:18280240, GO:0003785=PMID:20841568, GO:0007596=Reactome:REACT_604, GO:0048008=GO_REF:0000019, GO:0004713=PMID:11121037, GO:0004715=PMID:9461559, GO:0006464=PMID:8242749} P00519 Tyrosine-protein kinase ABL1 protein 20101115 {GO:0005515=IPI, GO:0051353=IDA, GO:2001020=IDA, GO:2000145=TAS, GO:0050731=IDA, GO:0030155=TAS, GO:0042692=TAS, GO:2000249=TAS, GO:0030100=TAS, GO:0007411=TAS, GO:0006298=TAS, GO:0070064=IDA, GO:0051019=IPI, GO:0031965=IEA, GO:0000287=IDA, GO:0018108=IDA, GO:0042770=IDA, GO:0051149=TAS, GO:0000115=TAS, GO:0045087=TAS, GO:0004515=TAS, GO:0010506=TAS, GO:0038096=TAS, GO:0017124=IPI, GO:0048471=IDA, GO:0030036=ISS, GO:0071901=IDA, GO:0005634=IDA, GO:0015629=TAS, GO:0005829=TAS, GO:0005739=IEA, GO:0005737=TAS, GO:0051726=IEA, GO:0007155=IEA, GO:0031252=IEA, GO:0006355=TAS, GO:0043065=IDA, GO:0030145=IDA, GO:0008630=TAS, GO:0006914=IEA, GO:0005730=IDA, GO:0008022=IPI, GO:0005524=IDA, GO:0003677=NAS, GO:0006974=IDA, GO:0006975=IDA, GO:0003785=TAS, GO:0007596=TAS, GO:0048008=IEA, GO:0004713=IDA, GO:0004715=IDA, GO:0006464=NAS} DNA damage induced protein phosphorylation, Fc-gamma receptor signaling pathway involved in phagocytosis, actin cytoskeleton organization, autophagy, axon guidance, blood coagulation, cell adhesion, cellular protein modification process, innate immune response, intrinsic apoptotic signaling pathway in response to DNA damage, mismatch repair, muscle cell differentiation, negative regulation of protein serine/threonine kinase activity, peptidyl-tyrosine phosphorylation, platelet-derived growth factor receptor signaling pathway, positive regulation of apoptotic process, positive regulation of muscle cell differentiation, positive regulation of oxidoreductase activity, positive regulation of peptidyl-tyrosine phosphorylation, regulation of actin cytoskeleton reorganization, regulation of autophagy, regulation of cell adhesion, regulation of cell cycle, regulation of cell motility, regulation of endocytosis, regulation of response to DNA damage stimulus, regulation of transcription involved in S phase of mitotic cell cycle, regulation of transcription, DNA-dependent, response to DNA damage stimulus, signal transduction in response to DNA damage actin cytoskeleton, cell leading edge, cytoplasm, cytosol, mitochondrion, nuclear membrane, nucleolus, nucleus, perinuclear region of cytoplasm ATP binding, DNA binding, SH3 domain binding, actin monomer binding, magnesium ion binding, manganese ion binding, mitogen-activated protein kinase binding, nicotinate-nucleotide adenylyltransferase activity, non-membrane spanning protein tyrosine kinase activity, proline-rich region binding, protein C-terminus binding, protein binding, protein tyrosine kinase activity NOT Human ABL2 BHF-UCL UniProtKB {GO:0005515=PMID:12893824, GO:0051353=PMID:12893824, GO:0071300=PMID:17910947, GO:2000145=PMID:20841568, GO:0015629=PMID:20841568, GO:0030155=PMID:20841568, GO:0005829=Reactome:REACT_19396, GO:2000249=PMID:20841568, GO:0051015=PMID:20841568, GO:0030100=PMID:20841568, GO:0007411=Reactome:REACT_18266, GO:0007155=GO_REF:0000037, GO:0051017=GO_REF:0000019, GO:0000287=PMID:15886098, GO:0030145=PMID:15886098, GO:0018108=PMID:15886098, GO:0005524=GO_REF:0000037, GO:0003785=PMID:20841568, GO:0007165=PMID:2198571, GO:0004672=PMID:2198571, GO:0010976=PMID:17910947, GO:0010506=PMID:20841568, GO:0004713=PMID:15886098, GO:0004715=PMID:20841568, GO:0006464=PMID:2198571} P42684 Abelson tyrosine-protein kinase 2 protein 20071108 {GO:0005515=IPI, GO:0051353=IDA, GO:0071300=IMP, GO:2000145=TAS, GO:0015629=TAS, GO:0030155=TAS, GO:0005829=TAS, GO:2000249=TAS, GO:0051015=TAS, GO:0030100=TAS, GO:0007411=TAS, GO:0007155=IEA, GO:0051017=IEA, GO:0000287=IDA, GO:0030145=IDA, GO:0018108=IDA, GO:0005524=IEA, GO:0003785=TAS, GO:0007165=TAS, GO:0004672=TAS, GO:0010976=IMP, GO:0010506=TAS, GO:0004713=IDA, GO:0004715=TAS, GO:0006464=TAS} actin filament bundle assembly, axon guidance, cell adhesion, cellular protein modification process, cellular response to retinoic acid, peptidyl-tyrosine phosphorylation, positive regulation of neuron projection development, positive regulation of oxidoreductase activity, regulation of actin cytoskeleton reorganization, regulation of autophagy, regulation of cell adhesion, regulation of cell motility, regulation of endocytosis, signal transduction actin cytoskeleton, cytosol ATP binding, actin filament binding, actin monomer binding, magnesium ion binding, manganese ion binding, non-membrane spanning protein tyrosine kinase activity, protein binding, protein kinase activity, protein tyrosine kinase activity Human ABLIM1 InterPro UniProtKB {GO:0005515=PMID:16189514, GO:0005737=GO_REF:0000039, GO:0007411=Reactome:REACT_18266, GO:0045944=GO_REF:0000019, GO:0007010=GO_REF:0000002, GO:0009887=PMID:9245787, GO:0008270=GO_REF:0000002, GO:0003779=GO_REF:0000002, GO:0015629=GO_REF:0000019, GO:0007601=PMID:9245787} Q5T6N4 Actin-binding LIM protein 1 protein 20130413 {GO:0005515=IPI, GO:0005737=IEA, GO:0007411=TAS, GO:0045944=IEA, GO:0007010=IEA, GO:0009887=TAS, GO:0008270=IEA, GO:0003779=IEA, GO:0015629=IEA, GO:0007601=TAS} axon guidance, cytoskeleton organization, organ morphogenesis, positive regulation of transcription from RNA polymerase II promoter, visual perception actin cytoskeleton, cytoplasm actin binding, protein binding, zinc ion binding Human InterPro:IPR001781 ABLIM2 HPA UniProtKB {GO:0005737=GO_REF:0000052, GO:0007411=Reactome:REACT_18266, GO:0045944=GO_REF:0000019, GO:0007010=GO_REF:0000002, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0008270=GO_REF:0000029, GO:0003779=GO_REF:0000002, GO:0045111=GO_REF:0000052, GO:0015629=PMID:17194709, GO:0030016=GO_REF:0000019} Q6H8Q1 Actin-binding LIM protein 2 protein 20101115 {GO:0005737=IDA, GO:0007411=TAS, GO:0045944=IEA, GO:0007010=IEA, GO:0005730=IDA, GO:0005634=IDA, GO:0008270=NAS, GO:0003779=IEA, GO:0045111=IDA, GO:0015629=IDA, GO:0030016=IEA} axon guidance, cytoskeleton organization, positive regulation of transcription from RNA polymerase II promoter actin cytoskeleton, cytoplasm, intermediate filament cytoskeleton, myofibril, nucleolus, nucleus actin binding, zinc ion binding Human ABLIM3 Reactome UniProtKB {GO:0005737=GO_REF:0000029, GO:0007411=Reactome:REACT_18266, GO:0045944=GO_REF:0000019, GO:0007010=GO_REF:0000002, GO:0003779=GO_REF:0000002, GO:0008270=GO_REF:0000029} O94929 Actin-binding LIM protein 3 protein 20130301 {GO:0005737=NAS, GO:0007411=TAS, GO:0045944=IEA, GO:0007010=IEA, GO:0003779=IEA, GO:0008270=NAS} axon guidance, cytoskeleton organization, positive regulation of transcription from RNA polymerase II promoter cytoplasm actin binding, zinc ion binding Human ABP1 MGI UniProtKB {GO:0071280=PMID:9399025, GO:0097185=PMID:16846222, GO:0005886=PMID:2217167, GO:0005272=PMID:2217167, GO:0005615=PMID:12072962, GO:0032403=PMID:19764817, GO:0042803=PMID:19764817, GO:0008144=PMID:2217167, GO:0004872=PMID:2217167, GO:0035725=PMID:2217167, GO:0008201=PMID:12072962, GO:0052600=GO_REF:0000003, GO:0046677=PMID:19764817, GO:0005777=PMID:1356107, GO:0005261=PMID:19764817, GO:0048038=PMID:12072962, GO:0005507=PMID:12072962, GO:0042493=PMID:8144586, GO:0005509=PMID:12072962, GO:0052599=GO_REF:0000003, GO:0052598=GO_REF:0000003, GO:0052597=PMID:9399025, GO:0008131=PMID:8144586, GO:0035874=PMID:9399025, GO:0071504=PMID:19764817, GO:0009308=GO_REF:0000002, GO:0008270=PMID:12072962, GO:0005923=GO_REF:0000024, GO:0055114=PMID:8144586, GO:0071420=PMID:12072962} P19801 "Amiloride-sensitive amine oxidase ""copper-containing""" protein 20060110 {GO:0071280=IDA, GO:0097185=IDA, GO:0005886=IDA, GO:0005272=TAS, GO:0005615=IDA, GO:0032403=IDA, GO:0042803=IPI, GO:0008144=IDA, GO:0004872=IDA, GO:0035725=TAS, GO:0008201=IDA, GO:0052600=IEA, GO:0046677=IDA, GO:0005777=NAS, GO:0005261=IDA, GO:0048038=IDA, GO:0005507=IDA, GO:0042493=IDA, GO:0005509=IDA, GO:0052599=IEA, GO:0052598=IEA, GO:0052597=IDA, GO:0008131=IDA, GO:0035874=IDA, GO:0071504=TAS, GO:0009308=IEA, GO:0008270=IDA, GO:0005923=ISS, GO:0055114=IDA, GO:0071420=IDA} amine metabolic process, cellular response to azide, cellular response to copper ion, cellular response to copper ion starvation, cellular response to heparin, cellular response to histamine, oxidation-reduction process, response to antibiotic, response to drug, sodium ion transmembrane transport extracellular space, peroxisome, plasma membrane, tight junction calcium ion binding, cation channel activity, copper ion binding, diamine oxidase activity, drug binding, heparin binding, histamine oxidase activity, methylputrescine oxidase activity, primary amine oxidase activity, propane-1,3-diamine oxidase activity, protein complex binding, protein homodimerization activity, quinone binding, receptor activity, sodium channel activity, zinc ion binding Human ABR Reactome UniProtKB {GO:0043314=GO_REF:0000019, GO:0051056=Reactome:REACT_11051, GO:0048011=Reactome:REACT_13776, GO:0030336=GO_REF:0000019, GO:0042472=GO_REF:0000019, GO:0030036=GO_REF:0000019, GO:0005886=GO_REF:0000019, GO:0007264=Reactome:REACT_11044, GO:0035023=GO_REF:0000002, GO:0006915=Reactome:REACT_13638, GO:0097190=Reactome:REACT_13720, GO:0005829=Reactome:REACT_19216, GO:0035556=GO_REF:0000002, GO:0005622=GO_REF:0000002, GO:0007165=GO_REF:0000002, GO:0050766=GO_REF:0000019, GO:0005543=GO_REF:0000002, GO:0007420=GO_REF:0000019, GO:0050728=GO_REF:0000019, GO:0050885=GO_REF:0000019, GO:0032496=GO_REF:0000019, GO:0005089=GO_REF:0000002, GO:0030675=GO_REF:0000019, GO:0005096=PMID:8262969} Q12979 Active breakpoint cluster region-related protein protein 20130301 {GO:0043314=IEA, GO:0051056=TAS, GO:0048011=TAS, GO:0030336=IEA, GO:0042472=IEA, GO:0030036=IEA, GO:0005886=IEA, GO:0007264=TAS, GO:0035023=IEA, GO:0006915=TAS, GO:0097190=TAS, GO:0005829=TAS, GO:0035556=IEA, GO:0005622=IEA, GO:0007165=IEA, GO:0050766=IEA, GO:0005543=IEA, GO:0007420=IEA, GO:0050728=IEA, GO:0050885=IEA, GO:0032496=IEA, GO:0005089=IEA, GO:0030675=IEA, GO:0005096=TAS} actin cytoskeleton organization, apoptotic process, apoptotic signaling pathway, brain development, inner ear morphogenesis, intracellular signal transduction, negative regulation of cell migration, negative regulation of inflammatory response, negative regulation of neutrophil degranulation, neuromuscular process controlling balance, neurotrophin TRK receptor signaling pathway, positive regulation of phagocytosis, regulation of Rho protein signal transduction, regulation of small GTPase mediated signal transduction, response to lipopolysaccharide, signal transduction, small GTPase mediated signal transduction cytosol, intracellular, plasma membrane GTPase activator activity, Rac GTPase activator activity, Rho guanyl-nucleotide exchange factor activity, phospholipid binding Human ABRA LIFEdb UniProtKB {GO:0051091=GO_REF:0000024, GO:0005886=GO_REF:0000054, GO:0045944=GO_REF:0000019, GO:0035025=GO_REF:0000024, GO:0003713=GO_REF:0000019, GO:0003779=GO_REF:0000024, GO:0015629=GO_REF:0000024, GO:0030017=GO_REF:0000024, GO:0006351=GO_REF:0000037, GO:0000060=GO_REF:0000019} Q8N0Z2 Actin-binding Rho-activating protein protein 20100607 {GO:0051091=ISS, GO:0005886=IDA, GO:0045944=IEA, GO:0035025=ISS, GO:0003713=IEA, GO:0003779=ISS, GO:0015629=ISS, GO:0030017=ISS, GO:0006351=IEA, GO:0000060=IEA} positive regulation of Rho protein signal transduction, positive regulation of sequence-specific DNA binding transcription factor activity, positive regulation of transcription from RNA polymerase II promoter, protein import into nucleus, translocation, transcription, DNA-dependent actin cytoskeleton, plasma membrane, sarcomere actin binding, transcription coactivator activity Human ABT1 PINC UniProtKB {GO:0005515=PMID:19299493, GO:0005667=GO_REF:0000019, GO:0021522=GO_REF:0000019, GO:0006366=GO_REF:0000019, GO:0006357=GO_REF:0000019, GO:0000166=GO_REF:0000002, GO:0003723=GO_REF:0000037, GO:0003713=PMID:10648625, GO:0005730=GO_REF:0000039, GO:0005634=PMID:10648625, GO:0003677=GO_REF:0000037} Q9ULW3 Activator of basal transcription 1 protein 20030904 {GO:0005515=IPI, GO:0005667=IEA, GO:0021522=IEA, GO:0006366=IEA, GO:0006357=IEA, GO:0000166=IEA, GO:0003723=IEA, GO:0003713=TAS, GO:0005730=IEA, GO:0005634=TAS, GO:0003677=IEA} regulation of transcription from RNA polymerase II promoter, spinal cord motor neuron differentiation, transcription from RNA polymerase II promoter nucleolus, nucleus, transcription factor complex DNA binding, RNA binding, nucleotide binding, protein binding, transcription coactivator activity Human ABTB1 HPA UniProtKB {GO:0005737=GO_REF:0000052, GO:0005886=GO_REF:0000052, GO:0005730=GO_REF:0000052, GO:0003746=GO_REF:0000037} Q969K4 Ankyrin repeat and BTB/POZ domain-containing protein 1 protein 20101115 {GO:0005737=IDA, GO:0005886=IDA, GO:0005730=IDA, GO:0003746=IEA} cytoplasm, nucleolus, plasma membrane translation elongation factor activity Human ABTB2 UniProtKB UniProtKB {GO:0003674=GO_REF:0000015, GO:0046982=GO_REF:0000002, GO:0005575=GO_REF:0000015, GO:0001558=GO_REF:0000029} Q8N961 Ankyrin repeat and BTB/POZ domain-containing protein 2 protein 20061026 {GO:0003674=ND, GO:0046982=IEA, GO:0005575=ND, GO:0001558=NAS} regulation of cell growth cellular_component molecular_function, protein heterodimerization activity Human ACAA1 HPA UniProtKB {GO:0005515=PMID:18281296, GO:0000038=PMID:2318981, GO:0016747=GO_REF:0000002, GO:0006635=PMID:2882519, GO:0005782=Reactome:REACT_121028, GO:0036109=Reactome:REACT_121147, GO:0044281=Reactome:REACT_111217, GO:0033559=Reactome:REACT_121284, GO:0043231=GO_REF:0000052, GO:0008206=PMID:2318981, GO:0033540=Reactome:REACT_17062, GO:0003988=GO_REF:0000003, GO:0044255=Reactome:REACT_16957} P09110 3-ketoacyl-CoA thiolase, peroxisomal protein 20110516 {GO:0005515=IPI, GO:0000038=IMP, GO:0016747=IEA, GO:0006635=IMP, GO:0005782=TAS, GO:0036109=TAS, GO:0044281=TAS, GO:0033559=TAS, GO:0043231=IDA, GO:0008206=IMP, GO:0033540=TAS, GO:0003988=IEA, GO:0044255=TAS} alpha-linolenic acid metabolic process, bile acid metabolic process, cellular lipid metabolic process, fatty acid beta-oxidation, fatty acid beta-oxidation using acyl-CoA oxidase, small molecule metabolic process, unsaturated fatty acid metabolic process, very long-chain fatty acid metabolic process intracellular membrane-bounded organelle, peroxisomal matrix acetyl-CoA C-acyltransferase activity, protein binding, transferase activity, transferring acyl groups other than amino-acyl groups Human ACAA2 UniProtKB UniProtKB {GO:0005515=PMID:18371312, GO:0005739=PMID:18371312, GO:0006695=PMID:8241273, GO:0043066=PMID:18371312, GO:0016747=GO_REF:0000002, GO:0006631=GO_REF:0000041, GO:0005743=GO_REF:0000019, GO:0003988=PMID:8241273} P42765 3-ketoacyl-CoA thiolase, mitochondrial protein 20101215 {GO:0005515=IPI, GO:0005739=IDA, GO:0006695=NAS, GO:0043066=IDA, GO:0016747=IEA, GO:0006631=IEA, GO:0005743=IEA, GO:0003988=NAS} cholesterol biosynthetic process, fatty acid metabolic process, negative regulation of apoptotic process mitochondrial inner membrane, mitochondrion acetyl-CoA C-acyltransferase activity, protein binding, transferase activity, transferring acyl groups other than amino-acyl groups Human UniProtKB:Q12983 ACACA InterPro UniProtKB {GO:0005515=PMID:16794074, GO:0006853=Reactome:REACT_11082, GO:0016874=GO_REF:0000002, GO:0055088=GO_REF:0000019, GO:0044281=Reactome:REACT_111217, GO:0035338=Reactome:REACT_1319, GO:2001295=GO_REF:0000041, GO:0006084=GO_REF:0000024, GO:0005524=GO_REF:0000002, GO:0046872=GO_REF:0000037, GO:0005829=Reactome:REACT_147816, GO:0005739=GO_REF:0000019, GO:0031325=Reactome:REACT_2122, GO:0006112=Reactome:REACT_1505, GO:0001894=GO_REF:0000019, GO:0051289=GO_REF:0000024, GO:0019432=Reactome:REACT_1190, GO:0004075=GO_REF:0000003, GO:0006633=GO_REF:0000002, GO:0003989=GO_REF:0000002, GO:0044255=Reactome:REACT_22279, GO:0044268=GO_REF:0000019} Q59FY4 Acetyl-Coenzyme A carboxylase alpha isoform 2 variant protein 20130413 {GO:0005515=IPI, GO:0006853=TAS, GO:0016874=IEA, GO:0055088=IEA, GO:0044281=TAS, GO:0035338=TAS, GO:2001295=IEA, GO:0006084=ISS, GO:0005524=IEA, GO:0046872=IEA, GO:0005829=TAS, GO:0005739=IEA, GO:0031325=TAS, GO:0006112=TAS, GO:0001894=IEA, GO:0051289=ISS, GO:0019432=TAS, GO:0004075=IEA, GO:0006633=IEA, GO:0003989=IEA, GO:0044255=TAS, GO:0044268=IEA} acetyl-CoA metabolic process, carnitine shuttle, cellular lipid metabolic process, energy reserve metabolic process, fatty acid biosynthetic process, lipid homeostasis, long-chain fatty-acyl-CoA biosynthetic process, malonyl-CoA biosynthetic process, multicellular organismal protein metabolic process, positive regulation of cellular metabolic process, protein homotetramerization, small molecule metabolic process, tissue homeostasis, triglyceride biosynthetic process cytosol, mitochondrion ATP binding, acetyl-CoA carboxylase activity, biotin carboxylase activity, ligase activity, metal ion binding, protein binding Human InterPro:IPR013537 ACACB HPA UniProtKB {GO:0005515=PMID:16794074, GO:0006853=Reactome:REACT_11082, GO:0044281=Reactome:REACT_111217, GO:2001295=GO_REF:0000041, GO:0005524=GO_REF:0000037, GO:0006084=PMID:20952656, GO:0046872=GO_REF:0000037, GO:0005829=Reactome:REACT_147743, GO:0012505=GO_REF:0000039, GO:0005739=GO_REF:0000019, GO:0005737=GO_REF:0000052, GO:0031325=Reactome:REACT_2122, GO:0006112=Reactome:REACT_1505, GO:0016020=GO_REF:0000037, GO:0051289=PMID:20952656, GO:0004075=GO_REF:0000003, GO:0006633=GO_REF:0000019, GO:0003989=PMID:20952656, GO:0044255=Reactome:REACT_22279} O00763 Acetyl-CoA carboxylase 2 protein 20120912 {GO:0005515=IPI, GO:0006853=TAS, GO:0044281=TAS, GO:2001295=IEA, GO:0005524=IEA, GO:0006084=IDA, GO:0046872=IEA, GO:0005829=TAS, GO:0012505=IEA, GO:0005739=IEA, GO:0005737=IDA, GO:0031325=TAS, GO:0006112=TAS, GO:0016020=IEA, GO:0051289=IDA, GO:0004075=IEA, GO:0006633=IEA, GO:0003989=IDA, GO:0044255=TAS} acetyl-CoA metabolic process, carnitine shuttle, cellular lipid metabolic process, energy reserve metabolic process, fatty acid biosynthetic process, malonyl-CoA biosynthetic process, positive regulation of cellular metabolic process, protein homotetramerization, small molecule metabolic process cytoplasm, cytosol, endomembrane system, membrane, mitochondrion ATP binding, acetyl-CoA carboxylase activity, biotin carboxylase activity, metal ion binding, protein binding Human ACAD10 UniProtKB UniProtKB {GO:0005739=PMID:21237683, GO:0016787=GO_REF:0000002, GO:0050660=GO_REF:0000002, GO:0003995=GO_REF:0000002, GO:0016627=GO_REF:0000002, GO:0016772=GO_REF:0000002} Q6JQN1 Acyl-CoA dehydrogenase family member 10 protein 20111024 {GO:0005739=NAS, GO:0016787=IEA, GO:0050660=IEA, GO:0003995=IEA, GO:0016627=IEA, GO:0016772=IEA} mitochondrion acyl-CoA dehydrogenase activity, flavin adenine dinucleotide binding, hydrolase activity, oxidoreductase activity, acting on the CH-CH group of donors, transferase activity, transferring phosphorus-containing groups Human ACAD11 HGNC UniProtKB {GO:0005739=GO_REF:0000019, GO:0017099=PMID:21237683, GO:0031966=PMID:21237683, GO:0050660=GO_REF:0000002, GO:0005634=PMID:21237683, GO:0003995=GO_REF:0000002, GO:0070991=PMID:21237683, GO:0033539=PMID:21237683, GO:0016627=GO_REF:0000002, GO:0004466=PMID:21237683, GO:0005777=GO_REF:0000024, GO:0016772=GO_REF:0000002} Q709F0 Acyl-CoA dehydrogenase family member 11 protein 20111020 {GO:0005739=IEA, GO:0017099=IDA, GO:0031966=IDA, GO:0050660=IEA, GO:0005634=IDA, GO:0003995=IEA, GO:0070991=IDA, GO:0033539=IDA, GO:0016627=IEA, GO:0004466=IDA, GO:0005777=ISS, GO:0016772=IEA} fatty acid beta-oxidation using acyl-CoA dehydrogenase mitochondrial membrane, mitochondrion, nucleus, peroxisome acyl-CoA dehydrogenase activity, flavin adenine dinucleotide binding, long-chain-acyl-CoA dehydrogenase activity, medium-chain-acyl-CoA dehydrogenase activity, oxidoreductase activity, acting on the CH-CH group of donors, transferase activity, transferring phosphorus-containing groups, very-long-chain-acyl-CoA dehydrogenase activity Human UniProtKB:B3DMA2 ACAD8 Reactome UniProtKB {GO:0006629=PMID:10524212, GO:0034641=Reactome:REACT_13, GO:0006355=GO_REF:0000037, GO:0005759=Reactome:REACT_630, GO:0050660=GO_REF:0000002, GO:0006574=GO_REF:0000041, GO:0009083=Reactome:REACT_197, GO:0003995=Reactome:REACT_630, GO:0044281=Reactome:REACT_111217, GO:0016627=GO_REF:0000002, GO:0006351=GO_REF:0000037} Q9UKU7 Isobutyryl-CoA dehydrogenase, mitochondrial protein 20100212 {GO:0006629=TAS, GO:0034641=TAS, GO:0006355=IEA, GO:0005759=TAS, GO:0050660=IEA, GO:0006574=IEA, GO:0009083=TAS, GO:0003995=EXP, GO:0044281=TAS, GO:0016627=IEA, GO:0006351=IEA} branched-chain amino acid catabolic process, cellular nitrogen compound metabolic process, lipid metabolic process, regulation of transcription, DNA-dependent, small molecule metabolic process, transcription, DNA-dependent, valine catabolic process mitochondrial matrix acyl-CoA dehydrogenase activity, flavin adenine dinucleotide binding, oxidoreductase activity, acting on the CH-CH group of donors Human ACAD9 LIFEdb UniProtKB {GO:0005739=GO_REF:0000054, GO:0050660=GO_REF:0000002, GO:0005634=PMID:21237683, GO:0003995=GO_REF:0000002, GO:0030425=PMID:21237683} Q9H845 Acyl-CoA dehydrogenase family member 9, mitochondrial protein 20100607 {GO:0005739=IDA, GO:0050660=IEA, GO:0005634=IDA, GO:0003995=IEA, GO:0030425=IDA} dendrite, mitochondrion, nucleus acyl-CoA dehydrogenase activity, flavin adenine dinucleotide binding Human ACADL HPA UniProtKB {GO:0090181=GO_REF:0000024, GO:0001659=GO_REF:0000024, GO:0031966=GO_REF:0000019, GO:0006635=Reactome:REACT_1473, GO:0016401=GO_REF:0000024, GO:0044242=GO_REF:0000024, GO:0050660=GO_REF:0000019, GO:0045717=GO_REF:0000024, GO:0046322=GO_REF:0000024, GO:0044281=Reactome:REACT_111217, GO:0033539=GO_REF:0000024, GO:0019254=GO_REF:0000024, GO:0004466=GO_REF:0000024, GO:0005739=GO_REF:0000052, GO:0005737=GO_REF:0000052, GO:0051289=GO_REF:0000019, GO:0005759=Reactome:REACT_2238, GO:0042758=GO_REF:0000019, GO:0003995=Reactome:REACT_2238, GO:0000062=GO_REF:0000019, GO:0044255=Reactome:REACT_22279, GO:0042413=GO_REF:0000024, GO:0055114=GO_REF:0000024} P28330 Long-chain specific acyl-CoA dehydrogenase, mitochondrial protein 20081203 {GO:0090181=ISS, GO:0001659=ISS, GO:0031966=IEA, GO:0006635=TAS, GO:0016401=ISS, GO:0044242=ISS, GO:0050660=IEA, GO:0045717=ISS, GO:0046322=ISS, GO:0044281=TAS, GO:0033539=ISS, GO:0019254=ISS, GO:0004466=ISS, GO:0005739=IDA, GO:0005737=IDA, GO:0051289=IEA, GO:0005759=TAS, GO:0042758=IEA, GO:0003995=TAS, GO:0000062=IEA, GO:0044255=TAS, GO:0042413=ISS, GO:0055114=ISS} carnitine catabolic process, carnitine metabolic process, CoA-linked, cellular lipid catabolic process, cellular lipid metabolic process, fatty acid beta-oxidation, fatty acid beta-oxidation using acyl-CoA dehydrogenase, long-chain fatty acid catabolic process, negative regulation of fatty acid biosynthetic process, negative regulation of fatty acid oxidation, oxidation-reduction process, protein homotetramerization, regulation of cholesterol metabolic process, small molecule metabolic process, temperature homeostasis cytoplasm, mitochondrial matrix, mitochondrial membrane, mitochondrion acyl-CoA dehydrogenase activity, fatty-acyl-CoA binding, flavin adenine dinucleotide binding, long-chain-acyl-CoA dehydrogenase activity, palmitoyl-CoA oxidase activity Human ACADM HPA UniProtKB {GO:0030424=PMID:21237683, GO:0006635=Reactome:REACT_1473, GO:0005978=GO_REF:0000019, GO:0050660=GO_REF:0000002, GO:0009409=GO_REF:0000019, GO:0044281=Reactome:REACT_111217, GO:0009791=GO_REF:0000019, GO:0019254=PMID:16972171, GO:0033539=PMID:1902818, GO:0016627=GO_REF:0000002, GO:0042802=PMID:19224950, GO:0001889=GO_REF:0000019, GO:0005739=GO_REF:0000052, GO:0006111=GO_REF:0000019, GO:0042594=GO_REF:0000019, GO:0005759=Reactome:REACT_116020, GO:0045329=PMID:16972171, GO:0051793=PMID:1970566, GO:0003995=GO_REF:0000002, GO:0051791=PMID:1970566, GO:0070991=PMID:1970566, GO:0055007=GO_REF:0000019, GO:0044255=Reactome:REACT_22279, GO:0055114=PMID:1902818} Q5T4U5 Acyl-Coenzyme A dehydrogenase, C-4 to C-12 straight chain, isoform CRA_a protein 20080205 {GO:0030424=IDA, GO:0006635=TAS, GO:0005978=IEA, GO:0050660=IEA, GO:0009409=IEA, GO:0044281=TAS, GO:0009791=IEA, GO:0019254=IMP, GO:0033539=IDA, GO:0016627=IEA, GO:0042802=IDA, GO:0001889=IEA, GO:0005739=IDA, GO:0006111=IEA, GO:0042594=IEA, GO:0005759=TAS, GO:0045329=IMP, GO:0051793=IDA, GO:0003995=IEA, GO:0051791=IDA, GO:0070991=IDA, GO:0055007=IEA, GO:0044255=TAS, GO:0055114=IDA} cardiac muscle cell differentiation, carnitine biosynthetic process, carnitine metabolic process, CoA-linked, cellular lipid metabolic process, fatty acid beta-oxidation, fatty acid beta-oxidation using acyl-CoA dehydrogenase, glycogen biosynthetic process, liver development, medium-chain fatty acid catabolic process, medium-chain fatty acid metabolic process, oxidation-reduction process, post-embryonic development, regulation of gluconeogenesis, response to cold, response to starvation, small molecule metabolic process axon, mitochondrial matrix, mitochondrion acyl-CoA dehydrogenase activity, flavin adenine dinucleotide binding, identical protein binding, medium-chain-acyl-CoA dehydrogenase activity, oxidoreductase activity, acting on the CH-CH group of donors Human ACADS Reactome UniProtKB {GO:0031966=GO_REF:0000019, GO:0006635=Reactome:REACT_1473, GO:0050660=GO_REF:0000002, GO:0004085=GO_REF:0000003, GO:0051384=GO_REF:0000019, GO:0044281=Reactome:REACT_111217, GO:0033539=GO_REF:0000019, GO:0005739=PMID:16729965, GO:0042594=GO_REF:0000019, GO:0051289=GO_REF:0000019, GO:0005759=Reactome:REACT_1592, GO:0003995=Reactome:REACT_1742, GO:0000062=GO_REF:0000019, GO:0046359=GO_REF:0000019, GO:0044255=Reactome:REACT_22279} P16219 Short-chain specific acyl-CoA dehydrogenase, mitochondrial protein 20130213 {GO:0031966=IEA, GO:0006635=TAS, GO:0050660=IEA, GO:0004085=IEA, GO:0051384=IEA, GO:0044281=TAS, GO:0033539=IEA, GO:0005739=IDA, GO:0042594=IEA, GO:0051289=IEA, GO:0005759=TAS, GO:0003995=TAS, GO:0000062=IEA, GO:0046359=IEA, GO:0044255=TAS} butyrate catabolic process, cellular lipid metabolic process, fatty acid beta-oxidation, fatty acid beta-oxidation using acyl-CoA dehydrogenase, protein homotetramerization, response to glucocorticoid stimulus, response to starvation, small molecule metabolic process mitochondrial matrix, mitochondrial membrane, mitochondrion acyl-CoA dehydrogenase activity, butyryl-CoA dehydrogenase activity, fatty-acyl-CoA binding, flavin adenine dinucleotide binding Human ACADSB Reactome UniProtKB {GO:0005739=PMID:7698750, GO:0034641=Reactome:REACT_13, GO:0005759=Reactome:REACT_1285, GO:0050660=GO_REF:0000002, GO:0006631=GO_REF:0000037, GO:0009083=Reactome:REACT_197, GO:0003995=Reactome:REACT_1285, GO:0044281=Reactome:REACT_111217} P45954 Short/branched chain specific acyl-CoA dehydrogenase, mitochondrial protein 20100211 {GO:0005739=TAS, GO:0034641=TAS, GO:0005759=TAS, GO:0050660=IEA, GO:0006631=IEA, GO:0009083=TAS, GO:0003995=EXP, GO:0044281=TAS} branched-chain amino acid catabolic process, cellular nitrogen compound metabolic process, fatty acid metabolic process, small molecule metabolic process mitochondrial matrix, mitochondrion acyl-CoA dehydrogenase activity, flavin adenine dinucleotide binding Human ACADVL BHF-UCL UniProtKB {GO:0042645=PMID:18063578, GO:0090181=GO_REF:0000024, GO:0001659=GO_REF:0000024, GO:0006635=Reactome:REACT_1473, GO:0050660=GO_REF:0000002, GO:0045717=GO_REF:0000024, GO:0005743=GO_REF:0000039, GO:0046322=GO_REF:0000024, GO:0044281=Reactome:REACT_111217, GO:0033539=GO_REF:0000024, GO:0016627=GO_REF:0000002, GO:0004466=PMID:8466512, GO:0030968=Reactome:REACT_18356, GO:0005739=GO_REF:0000024, GO:0005759=Reactome:REACT_115600, GO:0003995=Reactome:REACT_398, GO:0006987=Reactome:REACT_18368, GO:0044267=Reactome:REACT_17015, GO:0015980=PMID:7479827, GO:0044255=Reactome:REACT_22279} P49748 Very long-chain specific acyl-CoA dehydrogenase, mitochondrial protein 20100304 {GO:0042645=IDA, GO:0090181=ISS, GO:0001659=ISS, GO:0006635=TAS, GO:0050660=IEA, GO:0045717=ISS, GO:0005743=IEA, GO:0046322=ISS, GO:0044281=TAS, GO:0033539=ISS, GO:0016627=IEA, GO:0004466=TAS, GO:0030968=TAS, GO:0005739=ISS, GO:0005759=TAS, GO:0003995=TAS, GO:0006987=TAS, GO:0044267=TAS, GO:0015980=TAS, GO:0044255=TAS} activation of signaling protein activity involved in unfolded protein response, cellular lipid metabolic process, cellular protein metabolic process, endoplasmic reticulum unfolded protein response, energy derivation by oxidation of organic compounds, fatty acid beta-oxidation, fatty acid beta-oxidation using acyl-CoA dehydrogenase, negative regulation of fatty acid biosynthetic process, negative regulation of fatty acid oxidation, regulation of cholesterol metabolic process, small molecule metabolic process, temperature homeostasis mitochondrial inner membrane, mitochondrial matrix, mitochondrial nucleoid, mitochondrion acyl-CoA dehydrogenase activity, flavin adenine dinucleotide binding, long-chain-acyl-CoA dehydrogenase activity, oxidoreductase activity, acting on the CH-CH group of donors Human UniProtKB:P50544 ACAN InterPro UniProtKB {GO:0005515=PMID:17588949, GO:0005975=Reactome:REACT_474, GO:0005796=Reactome:REACT_121317, GO:0005509=GO_REF:0000002, GO:0005578=GO_REF:0000039, GO:0005576=Reactome:REACT_121303, GO:0044281=Reactome:REACT_111217, GO:0046872=GO_REF:0000037, GO:0042339=Reactome:REACT_121288, GO:0005604=GO_REF:0000019, GO:0030166=GO_REF:0000019, GO:0001501=PMID:1569188, GO:0005540=GO_REF:0000002, GO:0002063=GO_REF:0000019, GO:0018146=Reactome:REACT_121120, GO:0001502=GO_REF:0000019, GO:0030199=GO_REF:0000019, GO:0042340=Reactome:REACT_121313, GO:0006508=PMID:1569188, GO:0030246=GO_REF:0000002, GO:0007155=GO_REF:0000002, GO:0030203=Reactome:REACT_121315, GO:0043202=Reactome:REACT_121303, GO:0005201=PMID:1569188} Q6PID9 Aggrecan protein 20130413 {GO:0005515=IPI, GO:0005975=TAS, GO:0005796=TAS, GO:0005509=IEA, GO:0005578=IEA, GO:0005576=TAS, GO:0044281=TAS, GO:0046872=IEA, GO:0042339=TAS, GO:0005604=IEA, GO:0030166=IEA, GO:0001501=NAS, GO:0005540=IEA, GO:0002063=IEA, GO:0018146=TAS, GO:0001502=IEA, GO:0030199=IEA, GO:0042340=TAS, GO:0006508=NAS, GO:0030246=IEA, GO:0007155=IEA, GO:0030203=TAS, GO:0043202=TAS, GO:0005201=TAS} carbohydrate metabolic process, cartilage condensation, cell adhesion, chondrocyte development, collagen fibril organization, glycosaminoglycan metabolic process, keratan sulfate biosynthetic process, keratan sulfate catabolic process, keratan sulfate metabolic process, proteoglycan biosynthetic process, proteolysis, skeletal system development, small molecule metabolic process Golgi lumen, basement membrane, extracellular region, lysosomal lumen, proteinaceous extracellular matrix calcium ion binding, carbohydrate binding, extracellular matrix structural constituent, hyaluronic acid binding, metal ion binding, protein binding Human InterPro:IPR000538 ACAP1 UniProtKB UniProtKB {GO:0008060=GO_REF:0000002, GO:0005543=GO_REF:0000002, GO:0032312=GO_REF:0000002, GO:0008270=GO_REF:0000002, GO:0015031=GO_REF:0000037} Q15027 Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 1 protein 20130413 {GO:0008060=IEA, GO:0005543=IEA, GO:0032312=IEA, GO:0008270=IEA, GO:0015031=IEA} protein transport, regulation of ARF GTPase activity ARF GTPase activator activity, phospholipid binding, zinc ion binding Human UniProtKB-KW:KW-0653 ACAP2 InterPro UniProtKB {GO:0008060=GO_REF:0000002, GO:0005543=GO_REF:0000002, GO:0032312=GO_REF:0000002, GO:0008270=GO_REF:0000002} Q15057 Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 2 protein 20130413 {GO:0008060=IEA, GO:0005543=IEA, GO:0032312=IEA, GO:0008270=IEA} regulation of ARF GTPase activity ARF GTPase activator activity, phospholipid binding, zinc ion binding Human InterPro:IPR001164 ACAP3 InterPro UniProtKB {GO:0008060=GO_REF:0000002, GO:0005543=GO_REF:0000002, GO:0032312=GO_REF:0000002, GO:0008270=GO_REF:0000002} Q96P50 Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 3 protein 20130413 {GO:0008060=IEA, GO:0005543=IEA, GO:0032312=IEA, GO:0008270=IEA} regulation of ARF GTPase activity ARF GTPase activator activity, phospholipid binding, zinc ion binding Human InterPro:IPR001164 ACAT1 HPA UniProtKB {GO:0014070=GO_REF:0000019, GO:0050662=GO_REF:0000019, GO:0016747=GO_REF:0000002, GO:0072229=GO_REF:0000019, GO:0005743=GO_REF:0000019, GO:0009083=Reactome:REACT_197, GO:0044281=Reactome:REACT_111217, GO:0046872=GO_REF:0000037, GO:0042803=GO_REF:0000019, GO:0005739=GO_REF:0000052, GO:0001889=GO_REF:0000019, GO:0034641=Reactome:REACT_13, GO:0042594=GO_REF:0000019, GO:0046952=Reactome:REACT_59, GO:0007420=GO_REF:0000019, GO:0046951=Reactome:REACT_1464, GO:0005759=Reactome:REACT_1478, GO:0046950=Reactome:REACT_1861, GO:0003985=Reactome:REACT_1478, GO:0051260=GO_REF:0000019, GO:0009725=GO_REF:0000019, GO:0019899=GO_REF:0000019, GO:0060612=GO_REF:0000019, GO:0044255=Reactome:REACT_22279} P24752 Acetyl-CoA acetyltransferase, mitochondrial protein 20080818 {GO:0014070=IEA, GO:0050662=IEA, GO:0016747=IEA, GO:0072229=IEA, GO:0005743=IEA, GO:0009083=TAS, GO:0044281=TAS, GO:0046872=IEA, GO:0042803=IEA, GO:0005739=IDA, GO:0001889=IEA, GO:0034641=TAS, GO:0042594=IEA, GO:0046952=TAS, GO:0007420=IEA, GO:0046951=TAS, GO:0005759=TAS, GO:0046950=TAS, GO:0003985=EXP, GO:0051260=IEA, GO:0009725=IEA, GO:0019899=IEA, GO:0060612=IEA, GO:0044255=TAS} adipose tissue development, brain development, branched-chain amino acid catabolic process, cellular ketone body metabolic process, cellular lipid metabolic process, cellular nitrogen compound metabolic process, ketone body biosynthetic process, ketone body catabolic process, liver development, metanephric proximal convoluted tubule development, protein homooligomerization, response to hormone stimulus, response to organic cyclic compound, response to starvation, small molecule metabolic process mitochondrial inner membrane, mitochondrial matrix, mitochondrion acetyl-CoA C-acetyltransferase activity, coenzyme binding, enzyme binding, metal ion binding, protein homodimerization activity, transferase activity, transferring acyl groups other than amino-acyl groups Human ACAT2 HPA UniProtKB {GO:0006629=PMID:7911016, GO:0005739=GO_REF:0000052, GO:0005737=GO_REF:0000052, GO:0016747=GO_REF:0000002, GO:0005730=GO_REF:0000052, GO:0003985=PMID:7911016, GO:0005634=GO_REF:0000052} Q9BWD1 Acetyl-CoA acetyltransferase, cytosolic protein 20101115 {GO:0006629=IC, GO:0005739=IDA, GO:0005737=IDA, GO:0016747=IEA, GO:0005730=IDA, GO:0003985=IDA, GO:0005634=IDA} lipid metabolic process cytoplasm, mitochondrion, nucleolus, nucleus acetyl-CoA C-acetyltransferase activity, transferase activity, transferring acyl groups other than amino-acyl groups Human ACBD3 HPA UniProtKB {GO:0005739=GO_REF:0000039, GO:0006694=GO_REF:0000037, GO:0005794=GO_REF:0000052, GO:0000139=GO_REF:0000039, GO:0006810=GO_REF:0000002, GO:0016021=GO_REF:0000002, GO:0000062=GO_REF:0000002} Q9H3P7 Golgi resident protein GCP60 protein 20090616 {GO:0005739=IEA, GO:0006694=IEA, GO:0005794=IDA, GO:0000139=IEA, GO:0006810=IEA, GO:0016021=IEA, GO:0000062=IEA} steroid biosynthetic process, transport Golgi apparatus, Golgi membrane, integral to membrane, mitochondrion fatty-acyl-CoA binding Human ACBD4 UniProtKB UniProtKB {GO:0000062=GO_REF:0000002, GO:0008289=GO_REF:0000037} Q8NC06 Acyl-CoA-binding domain-containing protein 4 protein 20130413 {GO:0000062=IEA, GO:0008289=IEA} fatty-acyl-CoA binding, lipid binding Human UniProtKB-KW:KW-0446 ACBD5 InterPro UniProtKB {GO:0003674=GO_REF:0000015, GO:0008150=GO_REF:0000015, GO:0006810=GO_REF:0000037, GO:0016021=GO_REF:0000037, GO:0000062=GO_REF:0000002, GO:0005778=GO_REF:0000039, GO:0008289=GO_REF:0000037, GO:0043231=GO_REF:0000052} Q5T8E0 Acyl-CoA-binding domain-containing protein 5 protein 20130413 {GO:0003674=ND, GO:0008150=ND, GO:0006810=IEA, GO:0016021=IEA, GO:0000062=IEA, GO:0005778=IEA, GO:0008289=IEA, GO:0043231=IDA} biological_process, transport integral to membrane, intracellular membrane-bounded organelle, peroxisomal membrane fatty-acyl-CoA binding, lipid binding, molecular_function Human InterPro:IPR000582 ACBD6 HPA UniProtKB {GO:0005737=GO_REF:0000052, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0000062=GO_REF:0000002, GO:0008289=GO_REF:0000037} Q9BR61 Acyl-CoA-binding domain-containing protein 6 protein 20101115 {GO:0005737=IDA, GO:0005730=IDA, GO:0005634=IDA, GO:0000062=IEA, GO:0008289=IEA} cytoplasm, nucleolus, nucleus fatty-acyl-CoA binding, lipid binding Human ACCS UniProtKB UniProtKB {GO:0016847=PMID:11470512, GO:0030170=PMID:11470512, GO:0042803=PMID:11470512} Q96QU6 1-aminocyclopropane-1-carboxylate synthase-like protein 1 protein 20080109 {GO:0016847=IDA, GO:0030170=NAS, GO:0042803=NAS} 1-aminocyclopropane-1-carboxylate synthase activity, protein homodimerization activity, pyridoxal phosphate binding Human ACD BHF-UCL UniProtKB {GO:0005515=PMID:15380063, GO:0000781=PMID:15380063, GO:0016233=PMID:17237767, GO:0070182=PMID:17237767, GO:0001655=GO_REF:0000019, GO:0030326=GO_REF:0000019, GO:0003677=GO_REF:0000037, GO:0006886=PMID:15181449, GO:0031848=PMID:18185984, GO:0051973=PMID:17237768, GO:0032211=PMID:15380063, GO:0001501=GO_REF:0000019, GO:0060381=PMID:17237767, GO:0035282=GO_REF:0000019, GO:0000723=Reactome:REACT_7970, GO:0005654=Reactome:REACT_8031, GO:0070198=PMID:15181449, GO:0032202=PMID:16880378, GO:0000783=PMID:16880378} Q96AP0 Adrenocortical dysplasia protein homolog protein 20081205 {GO:0005515=IPI, GO:0000781=IDA, GO:0016233=NAS, GO:0070182=IPI, GO:0001655=IEA, GO:0030326=IEA, GO:0003677=IEA, GO:0006886=IMP, GO:0031848=ISS, GO:0051973=IDA, GO:0032211=IMP, GO:0001501=IEA, GO:0060381=IDA, GO:0035282=IEA, GO:0000723=TAS, GO:0005654=TAS, GO:0070198=IMP, GO:0032202=IMP, GO:0000783=IDA} embryonic limb morphogenesis, intracellular protein transport, negative regulation of telomere maintenance via telomerase, positive regulation of single-stranded telomeric DNA binding, positive regulation of telomerase activity, protection from non-homologous end joining at telomere, protein localization to chromosome, telomeric region, segmentation, skeletal system development, telomere assembly, telomere capping, telomere maintenance, urogenital system development chromosome, telomeric region, nuclear telomere cap complex, nucleoplasm DNA binding, DNA polymerase binding, protein binding Human ACE BHF-UCL UniProtKB {GO:0031404=PMID:12540854, GO:0005886=PMID:17077303, GO:0002003=Reactome:REACT_147707, GO:0014910=GO_REF:0000024, GO:0005615=PMID:4322742, GO:0019229=PMID:1668266, GO:0042312=PMID:4322742, GO:0003081=PMID:1668266, GO:0002019=PMID:1668266, GO:0008144=PMID:1320019, GO:0008241=PMID:11303049, GO:0004180=GO_REF:0000037, GO:0006508=GO_REF:0000037, GO:0043171=PMID:4322742, GO:0050482=PMID:17077303, GO:0031711=PMID:17077303, GO:0001822=PMID:16116425, GO:0005576=Reactome:REACT_147705, GO:0060218=PMID:7876104, GO:0016020=GO_REF:0000002, GO:0001974=PMID:1668266, GO:0042447=PMID:7876104, GO:0008217=PMID:11303049, GO:0002005=PMID:1668266, GO:0008270=PMID:12540854, GO:0016021=GO_REF:0000037, GO:0044267=Reactome:REACT_17015, GO:0009897=PMID:9449382, GO:0032943=PMID:7876104, GO:0008237=GO_REF:0000024, GO:0005768=PMID:17077303} P12821 Angiotensin-converting enzyme protein 20080903 {GO:0031404=IDA, GO:0005886=IDA, GO:0002003=TAS, GO:0014910=ISS, GO:0005615=IDA, GO:0019229=IC, GO:0042312=IC, GO:0003081=IC, GO:0002019=IC, GO:0008144=IDA, GO:0008241=ISS, GO:0004180=IEA, GO:0006508=IEA, GO:0043171=IDA, GO:0050482=IDA, GO:0031711=IPI, GO:0001822=IMP, GO:0005576=TAS, GO:0060218=IC, GO:0016020=IEA, GO:0001974=IC, GO:0042447=IDA, GO:0008217=ISS, GO:0002005=IC, GO:0008270=IDA, GO:0016021=IEA, GO:0044267=TAS, GO:0009897=IDA, GO:0032943=IC, GO:0008237=ISS, GO:0005768=IDA} angiotensin catabolic process in blood, angiotensin maturation, arachidonic acid secretion, blood vessel remodeling, cellular protein metabolic process, hematopoietic stem cell differentiation, hormone catabolic process, kidney development, mononuclear cell proliferation, peptide catabolic process, proteolysis, regulation of blood pressure, regulation of renal output by angiotensin, regulation of smooth muscle cell migration, regulation of systemic arterial blood pressure by renin-angiotensin, regulation of vasoconstriction, regulation of vasodilation endosome, external side of plasma membrane, extracellular region, extracellular space, integral to membrane, membrane, plasma membrane bradykinin receptor binding, carboxypeptidase activity, chloride ion binding, drug binding, metallopeptidase activity, peptidyl-dipeptidase activity, zinc ion binding Human ACE2 GOC UniProtKB {GO:0005886=Reactome:REACT_147889, GO:0002003=Reactome:REACT_147707, GO:0046718=PMID:15165741, GO:0001817=PMID:15380922, GO:0005615=PMID:18258853, GO:0019229=PMID:15380922, GO:0003081=PMID:18258853, GO:0042312=PMID:15380922, GO:0001948=PMID:18343844, GO:0001618=PMID:18343844, GO:0042127=PMID:17703127, GO:0006508=GO_REF:0000019, GO:0008241=PMID:10924499, GO:0004180=PMID:18258853, GO:0009986=PMID:18343844, GO:0050727=PMID:15380922, GO:0005576=PMID:10969042, GO:0009615=PMID:18343844, GO:0002005=PMID:10924499, GO:0032800=PMID:18258853, GO:0008270=PMID:10924499, GO:0045121=PMID:18279660, GO:0016021=GO_REF:0000037, GO:0017046=GO_REF:0000019, GO:2000379=PMID:15380922, GO:0046813=PMID:18343844, GO:0044267=Reactome:REACT_17015, GO:0003051=PMID:18258853, GO:0008237=PMID:10924499} Q9BYF1 Angiotensin-converting enzyme 2 protein 20130413 {GO:0005886=TAS, GO:0002003=TAS, GO:0046718=TAS, GO:0001817=IC, GO:0005615=IDA, GO:0019229=IC, GO:0003081=IMP, GO:0042312=IC, GO:0001948=IPI, GO:0001618=IDA, GO:0042127=TAS, GO:0006508=IEA, GO:0008241=IDA, GO:0004180=IDA, GO:0009986=IDA, GO:0050727=IC, GO:0005576=IDA, GO:0009615=IDA, GO:0002005=IC, GO:0032800=IMP, GO:0008270=TAS, GO:0045121=TAS, GO:0016021=IEA, GO:0017046=IEA, GO:2000379=IC, GO:0046813=IDA, GO:0044267=TAS, GO:0003051=IMP, GO:0008237=IDA} angiotensin catabolic process in blood, angiotensin maturation, angiotensin-mediated drinking behavior, cellular protein metabolic process, positive regulation of reactive oxygen species metabolic process, proteolysis, receptor biosynthetic process, regulation of cell proliferation, regulation of cytokine production, regulation of inflammatory response, regulation of systemic arterial blood pressure by renin-angiotensin, regulation of vasoconstriction, regulation of vasodilation, response to virus, viral entry into host cell, virion attachment, binding of host cell surface receptor cell surface, extracellular region, extracellular space, integral to membrane, membrane raft, plasma membrane carboxypeptidase activity, glycoprotein binding, metallopeptidase activity, peptide hormone binding, peptidyl-dipeptidase activity, viral receptor activity, zinc ion binding Human ACER3 Reactome UniProtKB {GO:0070774=PMID:20068046, GO:0006665=Reactome:REACT_19323, GO:0008284=PMID:20068046, GO:0016811=GO_REF:0000002, GO:0006672=GO_REF:0000002, GO:0030148=Reactome:REACT_115810, GO:0071602=PMID:20068046, GO:0030176=PMID:11356846, GO:0044281=Reactome:REACT_111217, GO:0030173=PMID:11356846, GO:0005789=Reactome:REACT_19134, GO:0016021=GO_REF:0000002, GO:0046512=PMID:20068046} Q9NUN7 Alkaline ceramidase 3 protein 20130301 {GO:0070774=IDA, GO:0006665=TAS, GO:0008284=IMP, GO:0016811=IEA, GO:0006672=IEA, GO:0030148=TAS, GO:0071602=IDA, GO:0030176=IDA, GO:0044281=TAS, GO:0030173=IDA, GO:0005789=TAS, GO:0016021=IEA, GO:0046512=IDA} ceramide metabolic process, phytosphingosine biosynthetic process, positive regulation of cell proliferation, small molecule metabolic process, sphingolipid biosynthetic process, sphingolipid metabolic process, sphingosine biosynthetic process endoplasmic reticulum membrane, integral to Golgi membrane, integral to endoplasmic reticulum membrane, integral to membrane hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides, phytoceramidase activity Human ACHE BHF-UCL UniProtKB {GO:0004091=GO_REF:0000033, GO:0005515=PMID:18194455, GO:0003990=PMID:1517212, GO:0030054=GO_REF:0000037, GO:0031594=GO_REF:0000033, GO:0060041=GO_REF:0000019, GO:0005518=PMID:12524166, GO:0045202=PMID:8460160, GO:0031225=GO_REF:0000037, GO:0043621=GO_REF:0000019, GO:0005615=GO_REF:0000033, GO:0042803=PMID:12524166, GO:0031623=GO_REF:0000019, GO:0045211=GO_REF:0000033, GO:0042166=PMID:8349597, GO:0006656=Reactome:REACT_121238, GO:0005794=PMID:15454088, GO:0009986=GO_REF:0000033, GO:0005605=PMID:16289501, GO:0045212=GO_REF:0000019, GO:0007416=PMID:11283752, GO:0007271=GO_REF:0000033, GO:0042734=GO_REF:0000033, GO:0007517=PMID:11283752, GO:0032223=PMID:1517212, GO:0002076=PMID:15454088, GO:0043236=PMID:12524166, GO:0001507=PMID:1517212, GO:0005788=GO_REF:0000033, GO:0006581=PMID:1517212, GO:0006644=Reactome:REACT_120870, GO:0050770=GO_REF:0000033, GO:0030424=GO_REF:0000033, GO:0048471=PMID:14766237, GO:0005886=Reactome:REACT_14816, GO:0008283=PMID:11283752, GO:0004104=PMID:1517212, GO:0050714=PMID:11283752, GO:0007268=Reactome:REACT_13685, GO:0005634=GO_REF:0000039, GO:0044281=Reactome:REACT_111217, GO:0019695=GO_REF:0000033, GO:0030425=GO_REF:0000033, GO:0001540=PMID:11283752, GO:0017171=PMID:3954986, GO:0007155=PMID:15454088, GO:0051262=GO_REF:0000019, GO:0009611=PMID:11283752, GO:0005576=PMID:1517212, GO:0042982=PMID:12769797, GO:0007399=PMID:11283752, GO:0048814=GO_REF:0000033, GO:0006260=PMID:11283752, GO:0001919=GO_REF:0000019, GO:0016020=PMID:16262697, GO:0016787=PMID:1517212, GO:0042136=Reactome:REACT_13583, GO:0046474=Reactome:REACT_121401} P22303 Acetylcholinesterase protein 20120102 {GO:0004091=IBA, GO:0005515=IPI, GO:0003990=IDA, GO:0030054=IEA, GO:0031594=IBA, GO:0060041=IEA, GO:0005518=IDA, GO:0045202=IDA, GO:0031225=IEA, GO:0043621=IEA, GO:0005615=IBA, GO:0042803=IPI, GO:0031623=IEA, GO:0045211=IBA, GO:0042166=IDA, GO:0006656=TAS, GO:0005794=IDA, GO:0009986=IBA, GO:0005605=NAS, GO:0045212=IEA, GO:0007416=TAS, GO:0007271=IBA, GO:0042734=IBA, GO:0007517=TAS, GO:0032223=IC, GO:0002076=IEP, GO:0043236=IDA, GO:0001507=NAS, GO:0005788=IBA, GO:0006581=IDA, GO:0006644=TAS, GO:0050770=IBA, GO:0030424=IBA, GO:0048471=IDA, GO:0005886=TAS, GO:0008283=TAS, GO:0004104=IDA, GO:0050714=TAS, GO:0007268=TAS, GO:0005634=IEA, GO:0044281=TAS, GO:0019695=IBA, GO:0030425=IBA, GO:0001540=TAS, GO:0017171=IDA, GO:0007155=IDA, GO:0051262=IEA, GO:0009611=TAS, GO:0005576=IDA, GO:0042982=TAS, GO:0007399=TAS, GO:0048814=IBA, GO:0006260=TAS, GO:0001919=IEA, GO:0016020=IDA, GO:0016787=IDA, GO:0042136=TAS, GO:0046474=TAS} DNA replication, acetylcholine catabolic process, acetylcholine catabolic process in synaptic cleft, amyloid precursor protein metabolic process, cell adhesion, cell proliferation, choline metabolic process, glycerophospholipid biosynthetic process, muscle organ development, negative regulation of synaptic transmission, cholinergic, nervous system development, neurotransmitter biosynthetic process, neurotransmitter receptor biosynthetic process, osteoblast development, phosphatidylcholine biosynthetic process, phospholipid metabolic process, positive regulation of protein secretion, protein tetramerization, receptor internalization, regulation of axonogenesis, regulation of dendrite morphogenesis, regulation of receptor recycling, response to wounding, retina development in camera-type eye, small molecule metabolic process, synapse assembly, synaptic transmission, synaptic transmission, cholinergic Golgi apparatus, anchored to membrane, axon, basal lamina, cell junction, cell surface, dendrite, endoplasmic reticulum lumen, extracellular region, extracellular space, membrane, neuromuscular junction, nucleus, perinuclear region of cytoplasm, plasma membrane, postsynaptic membrane, presynaptic membrane, synapse acetylcholine binding, acetylcholinesterase activity, beta-amyloid binding, carboxylesterase activity, cholinesterase activity, collagen binding, hydrolase activity, laminin binding, protein binding, protein homodimerization activity, protein self-association, serine hydrolase activity Human ACIN1 GOC UniProtKB {GO:0005515=PMID:20195357, GO:0006200=PMID:10490026, GO:0005730=GO_REF:0000052, GO:0006915=Reactome:REACT_578, GO:0005634=GO_REF:0000052, GO:0003676=PMID:10490026, GO:0006921=Reactome:REACT_995, GO:0005829=Reactome:REACT_12450, GO:0005737=GO_REF:0000052, GO:0000166=GO_REF:0000002, GO:0016607=GO_REF:0000039, GO:0045657=PMID:12393560, GO:0030218=PMID:11208865, GO:0030263=PMID:10490026, GO:0019899=PMID:10490026, GO:0016887=PMID:10490026} Q9UKV3 Apoptotic chromatin condensation inducer in the nucleus protein 20130413 {GO:0005515=IPI, GO:0006200=NAS, GO:0005730=IDA, GO:0006915=TAS, GO:0005634=IDA, GO:0003676=NAS, GO:0006921=TAS, GO:0005829=TAS, GO:0005737=IDA, GO:0000166=IEA, GO:0016607=IEA, GO:0045657=IEP, GO:0030218=IEP, GO:0030263=IDA, GO:0019899=NAS, GO:0016887=NAS} ATP catabolic process, apoptotic chromosome condensation, apoptotic process, cellular component disassembly involved in execution phase of apoptosis, erythrocyte differentiation, positive regulation of monocyte differentiation cytoplasm, cytosol, nuclear speck, nucleolus, nucleus ATPase activity, enzyme binding, nucleic acid binding, nucleotide binding, protein binding Human ACLY HPA UniProtKB {GO:0048037=GO_REF:0000002, GO:0044262=GO_REF:0000002, GO:0005886=GO_REF:0000052, GO:0006200=PMID:1371749, GO:0003878=Reactome:REACT_1141, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0044281=Reactome:REACT_111217, GO:0035338=Reactome:REACT_1319, GO:0015936=PMID:1371749, GO:0005524=GO_REF:0000037, GO:0009346=PMID:1371749, GO:0046872=GO_REF:0000037, GO:0005829=Reactome:REACT_1577, GO:0005739=GO_REF:0000019, GO:0006101=PMID:1371749, GO:0005737=GO_REF:0000052, GO:0031325=Reactome:REACT_2122, GO:0006112=Reactome:REACT_1505, GO:0019432=Reactome:REACT_1190, GO:0004775=GO_REF:0000002, GO:0044255=Reactome:REACT_22279} P53396 ATP-citrate synthase protein 20111111 {GO:0048037=IEA, GO:0044262=IEA, GO:0005886=IDA, GO:0006200=TAS, GO:0003878=TAS, GO:0005730=IDA, GO:0005634=IDA, GO:0044281=TAS, GO:0035338=TAS, GO:0015936=TAS, GO:0005524=IEA, GO:0009346=TAS, GO:0046872=IEA, GO:0005829=TAS, GO:0005739=IEA, GO:0006101=TAS, GO:0005737=IDA, GO:0031325=TAS, GO:0006112=TAS, GO:0019432=TAS, GO:0004775=IEA, GO:0044255=TAS} ATP catabolic process, cellular carbohydrate metabolic process, cellular lipid metabolic process, citrate metabolic process, coenzyme A metabolic process, energy reserve metabolic process, long-chain fatty-acyl-CoA biosynthetic process, positive regulation of cellular metabolic process, small molecule metabolic process, triglyceride biosynthetic process citrate lyase complex, cytoplasm, cytosol, mitochondrion, nucleolus, nucleus, plasma membrane ATP binding, ATP citrate synthase activity, cofactor binding, metal ion binding, succinate-CoA ligase (ADP-forming) activity Human ACMSD Reactome UniProtKB {GO:0034641=Reactome:REACT_13, GO:0006569=Reactome:REACT_916, GO:0046874=PMID:12140278, GO:0044281=Reactome:REACT_111217, GO:0001760=PMID:12140278, GO:0046872=GO_REF:0000037, GO:0005829=PMID:12140278} Q8TDX5 2-amino-3-carboxymuconate-6-semialdehyde decarboxylase protein 20130213 {GO:0034641=TAS, GO:0006569=TAS, GO:0046874=IDA, GO:0044281=TAS, GO:0001760=IDA, GO:0046872=IEA, GO:0005829=IDA} cellular nitrogen compound metabolic process, quinolinate metabolic process, small molecule metabolic process, tryptophan catabolic process cytosol aminocarboxymuconate-semialdehyde decarboxylase activity, metal ion binding Human ACO1 InterPro UniProtKB {GO:0005515=PMID:19762596, GO:0005794=PMID:16144863, GO:0051539=PMID:16407072, GO:0006099=GO_REF:0000037, GO:0005783=PMID:16144863, GO:0003994=PMID:8041788, GO:0003723=PMID:1946430, GO:0010040=PMID:8041788, GO:0009791=GO_REF:0000019, GO:0046872=GO_REF:0000037, GO:0006417=GO_REF:0000019, GO:0005829=PMID:16527810, GO:0005739=GO_REF:0000052, GO:0006879=GO_REF:0000019, GO:0006101=PMID:16527810, GO:0050892=GO_REF:0000019, GO:0005737=GO_REF:0000052, GO:0052633=GO_REF:0000003, GO:0008152=GO_REF:0000002, GO:0052632=GO_REF:0000003, GO:0030350=PMID:8041788} Q5VZA6 Cytoplasmic aconitate hydratase protein 20130413 {GO:0005515=IPI, GO:0005794=IDA, GO:0051539=IDA, GO:0006099=IEA, GO:0005783=IDA, GO:0003994=IDA, GO:0003723=IDA, GO:0010040=IDA, GO:0009791=IEA, GO:0046872=IEA, GO:0006417=IEA, GO:0005829=IDA, GO:0005739=IDA, GO:0006879=IEA, GO:0006101=IDA, GO:0050892=IEA, GO:0005737=IDA, GO:0052633=IEA, GO:0008152=IEA, GO:0052632=IEA, GO:0030350=IDA} cellular iron ion homeostasis, citrate metabolic process, intestinal absorption, metabolic process, post-embryonic development, regulation of translation, response to iron(II) ion, tricarboxylic acid cycle Golgi apparatus, cytoplasm, cytosol, endoplasmic reticulum, mitochondrion 4 iron, 4 sulfur cluster binding, RNA binding, aconitate hydratase activity, citrate hydro-lyase (cis-aconitate-forming) activity, iron-responsive element binding, isocitrate hydro-lyase (cis-aconitate-forming) activity, metal ion binding, protein binding Human InterPro:IPR001030|InterPro:IPR015931|InterPro:IPR015932|InterPro:IPR015934|InterPro:IPR015937 ACO2 HPA UniProtKB {GO:0008219=GO_REF:0000037, GO:0051538=GO_REF:0000019, GO:0006099=Reactome:REACT_1785, GO:0051539=GO_REF:0000019, GO:0005506=PMID:9630632, GO:0003994=GO_REF:0000002, GO:0005634=GO_REF:0000052, GO:0044281=Reactome:REACT_111217, GO:0006091=PMID:9630632, GO:0005739=GO_REF:0000052, GO:0006102=GO_REF:0000019, GO:0006101=PMID:9630632, GO:0005759=Reactome:REACT_21262, GO:0052633=GO_REF:0000003, GO:0052632=GO_REF:0000003} Q99798 Aconitate hydratase, mitochondrial protein 20101115 {GO:0008219=IEA, GO:0051538=IEA, GO:0006099=TAS, GO:0051539=IEA, GO:0005506=IDA, GO:0003994=IEA, GO:0005634=IDA, GO:0044281=TAS, GO:0006091=TAS, GO:0005739=IDA, GO:0006102=IEA, GO:0006101=IDA, GO:0005759=TAS, GO:0052633=IEA, GO:0052632=IEA} cell death, citrate metabolic process, generation of precursor metabolites and energy, isocitrate metabolic process, small molecule metabolic process, tricarboxylic acid cycle mitochondrial matrix, mitochondrion, nucleus 3 iron, 4 sulfur cluster binding, 4 iron, 4 sulfur cluster binding, aconitate hydratase activity, citrate hydro-lyase (cis-aconitate-forming) activity, iron ion binding, isocitrate hydro-lyase (cis-aconitate-forming) activity Human ACOT1 HPA UniProtKB {GO:0047617=PMID:16940157, GO:0004091=GO_REF:0000037, GO:0005739=GO_REF:0000052, GO:0000038=PMID:16940157, GO:0006637=PMID:16940157, GO:0001676=PMID:16940157, GO:0016290=GO_REF:0000003, GO:0016790=GO_REF:0000002, GO:0005829=PMID:16940157} Q86TX2 Acyl-coenzyme A thioesterase 1 protein 20111111 {GO:0047617=IDA, GO:0004091=IEA, GO:0005739=IDA, GO:0000038=IDA, GO:0006637=IDA, GO:0001676=IDA, GO:0016290=IEA, GO:0016790=IEA, GO:0005829=IDA} acyl-CoA metabolic process, long-chain fatty acid metabolic process, very long-chain fatty acid metabolic process cytosol, mitochondrion acyl-CoA hydrolase activity, carboxylesterase activity, palmitoyl-CoA hydrolase activity, thiolester hydrolase activity Human ACOT13 UniProtKB UniProtKB {GO:0047617=PMID:16934754, GO:0005739=GO_REF:0000039, GO:0051289=PMID:16934754} Q9NPJ3 Acyl-coenzyme A thioesterase 13 protein 20090521 {GO:0047617=IDA, GO:0005739=IEA, GO:0051289=IPI} protein homotetramerization mitochondrion acyl-CoA hydrolase activity Human ACOT2 HPA UniProtKB {GO:0047617=PMID:16940157, GO:0004091=GO_REF:0000037, GO:0005739=GO_REF:0000052, GO:0000038=PMID:16940157, GO:0006637=PMID:16940157, GO:0001676=PMID:16940157, GO:0016290=GO_REF:0000003, GO:0005102=PMID:20178365} P49753 Acyl-coenzyme A thioesterase 2, mitochondrial protein 20111111 {GO:0047617=IDA, GO:0004091=IEA, GO:0005739=IDA, GO:0000038=IDA, GO:0006637=IDA, GO:0001676=IDA, GO:0016290=IEA, GO:0005102=IPI} acyl-CoA metabolic process, long-chain fatty acid metabolic process, very long-chain fatty acid metabolic process mitochondrion acyl-CoA hydrolase activity, carboxylesterase activity, palmitoyl-CoA hydrolase activity, receptor binding Human ACOT4 HGNC UniProtKB {GO:0004091=GO_REF:0000037, GO:0004778=PMID:16141203, GO:0000038=PMID:16940157, GO:0006637=PMID:16940157, GO:0001676=PMID:16940157, GO:0046459=PMID:16940157, GO:0043648=PMID:16940157, GO:0016290=GO_REF:0000003, GO:0043649=PMID:16141203, GO:0005102=PMID:20178365, GO:0047617=PMID:16940157, GO:0032789=PMID:16940157, GO:0032788=PMID:16940157, GO:0006104=PMID:16940157, GO:0019605=PMID:16940157, GO:0005777=PMID:16940157} Q8N9L9 Acyl-coenzyme A thioesterase 4 protein 20061213 {GO:0004091=IEA, GO:0004778=IDA, GO:0000038=IDA, GO:0006637=IDA, GO:0001676=IDA, GO:0046459=IDA, GO:0043648=IDA, GO:0016290=IEA, GO:0043649=IDA, GO:0005102=IPI, GO:0047617=IDA, GO:0032789=IDA, GO:0032788=IDA, GO:0006104=IDA, GO:0019605=IDA, GO:0005777=IDA} acyl-CoA metabolic process, butyrate metabolic process, dicarboxylic acid catabolic process, dicarboxylic acid metabolic process, long-chain fatty acid metabolic process, saturated monocarboxylic acid metabolic process, short-chain fatty acid metabolic process, succinyl-CoA metabolic process, unsaturated monocarboxylic acid metabolic process, very long-chain fatty acid metabolic process peroxisome acyl-CoA hydrolase activity, carboxylesterase activity, palmitoyl-CoA hydrolase activity, receptor binding, succinyl-CoA hydrolase activity Human ACOT7 PINC UniProtKB {GO:0006629=PMID:10578051, GO:0005739=GO_REF:0000039, GO:0004091=GO_REF:0000037, GO:0043005=GO_REF:0000019, GO:0005737=PMID:10578051, GO:0016290=GO_REF:0000003, GO:0003824=PMID:10578051, GO:0000062=PMID:10578051, GO:0044297=GO_REF:0000019, GO:0009062=GO_REF:0000019, GO:0005829=GO_REF:0000019} O00154 Cytosolic acyl coenzyme A thioester hydrolase protein 20030904 {GO:0006629=TAS, GO:0005739=IEA, GO:0004091=IEA, GO:0043005=IEA, GO:0005737=TAS, GO:0016290=IEA, GO:0003824=TAS, GO:0000062=TAS, GO:0044297=IEA, GO:0009062=IEA, GO:0005829=IEA} fatty acid catabolic process, lipid metabolic process cell body, cytoplasm, cytosol, mitochondrion, neuron projection carboxylesterase activity, catalytic activity, fatty-acyl-CoA binding, palmitoyl-CoA hydrolase activity Human ACOT8 InterPro UniProtKB {GO:0004091=GO_REF:0000037, GO:0005515=PMID:22190034, GO:0052815=PMID:9299485, GO:0006637=GO_REF:0000002, GO:0005782=Reactome:REACT_120988, GO:0006699=Reactome:REACT_11054, GO:0043649=PMID:16141203, GO:0016290=PMID:9299485, GO:0005102=PMID:20178365, GO:0044281=Reactome:REACT_111217, GO:0036109=Reactome:REACT_121147, GO:0033559=Reactome:REACT_121284, GO:0047617=GO_REF:0000002, GO:0005739=GO_REF:0000019, GO:0019048=GO_REF:0000037, GO:0008206=Reactome:REACT_11040, GO:0033540=Reactome:REACT_17062, GO:0044255=Reactome:REACT_16957, GO:0033882=GO_REF:0000003} Q9BR14 Acyl-coenzyme A thioesterase 8 protein 20130413 {GO:0004091=IEA, GO:0005515=IPI, GO:0052815=IDA, GO:0006637=IEA, GO:0005782=TAS, GO:0006699=TAS, GO:0043649=IDA, GO:0016290=IDA, GO:0005102=IPI, GO:0044281=TAS, GO:0036109=TAS, GO:0033559=TAS, GO:0047617=IEA, GO:0005739=IEA, GO:0019048=IEA, GO:0008206=TAS, GO:0033540=TAS, GO:0044255=TAS, GO:0033882=IEA} acyl-CoA metabolic process, alpha-linolenic acid metabolic process, bile acid biosynthetic process, bile acid metabolic process, cellular lipid metabolic process, dicarboxylic acid catabolic process, fatty acid beta-oxidation using acyl-CoA oxidase, small molecule metabolic process, unsaturated fatty acid metabolic process, virus-host interaction mitochondrion, peroxisomal matrix acyl-CoA hydrolase activity, carboxylesterase activity, choloyl-CoA hydrolase activity, medium-chain acyl-CoA hydrolase activity, palmitoyl-CoA hydrolase activity, protein binding, receptor binding Human InterPro:IPR003703 ACOT9 HGNC UniProtKB {GO:0005739=GO_REF:0000024, GO:0004091=GO_REF:0000037, GO:0006637=GO_REF:0000024, GO:0003986=GO_REF:0000024} Q9Y305 Acyl-coenzyme A thioesterase 9, mitochondrial protein 20050921 {GO:0005739=ISS, GO:0004091=IEA, GO:0006637=ISS, GO:0003986=ISS} acyl-CoA metabolic process mitochondrion acetyl-CoA hydrolase activity, carboxylesterase activity Human UniProtKB:Q9R0X4 ACOX1 BHF-UCL UniProtKB {GO:0006629=PMID:8117268, GO:0000038=PMID:18536048, GO:0019395=PMID:7876265, GO:0005504=GO_REF:0000019, GO:0006693=PMID:7876265, GO:0006635=GO_REF:0000002, GO:0016401=GO_REF:0000019, GO:0005782=Reactome:REACT_120938, GO:0050660=GO_REF:0000002, GO:0005102=PMID:20178365, GO:0006091=PMID:7876265, GO:0007283=GO_REF:0000019, GO:0044281=Reactome:REACT_111217, GO:0036109=Reactome:REACT_121147, GO:0033559=Reactome:REACT_121284, GO:0005739=GO_REF:0000019, GO:0047485=PMID:18281296, GO:0003997=PMID:18536048, GO:0006631=GO_REF:0000002, GO:0003995=GO_REF:0000002, GO:0033540=PMID:18536048, GO:0044255=Reactome:REACT_22279, GO:0005778=GO_REF:0000019, GO:0005777=PMID:8117268} Q15067 Peroxisomal acyl-coenzyme A oxidase 1 protein 20091126 {GO:0006629=IDA, GO:0000038=IMP, GO:0019395=IMP, GO:0005504=IEA, GO:0006693=IMP, GO:0006635=IEA, GO:0016401=IEA, GO:0005782=TAS, GO:0050660=IEA, GO:0005102=IPI, GO:0006091=IMP, GO:0007283=IEA, GO:0044281=TAS, GO:0036109=TAS, GO:0033559=TAS, GO:0005739=IEA, GO:0047485=IPI, GO:0003997=IMP, GO:0006631=IEA, GO:0003995=IEA, GO:0033540=IMP, GO:0044255=TAS, GO:0005778=IEA, GO:0005777=IDA} alpha-linolenic acid metabolic process, cellular lipid metabolic process, fatty acid beta-oxidation, fatty acid beta-oxidation using acyl-CoA oxidase, fatty acid metabolic process, fatty acid oxidation, generation of precursor metabolites and energy, lipid metabolic process, prostaglandin metabolic process, small molecule metabolic process, spermatogenesis, unsaturated fatty acid metabolic process, very long-chain fatty acid metabolic process mitochondrion, peroxisomal matrix, peroxisomal membrane, peroxisome acyl-CoA dehydrogenase activity, acyl-CoA oxidase activity, fatty acid binding, flavin adenine dinucleotide binding, palmitoyl-CoA oxidase activity, protein N-terminus binding, receptor binding Human ACOX2 Reactome UniProtKB {GO:0016402=Reactome:REACT_17014, GO:0006635=GO_REF:0000002, GO:0005782=Reactome:REACT_17014, GO:0006699=Reactome:REACT_11054, GO:0033791=GO_REF:0000003, GO:0050660=GO_REF:0000002, GO:0005102=PMID:20178365, GO:0044281=Reactome:REACT_111217, GO:0003997=Reactome:REACT_10074, GO:0006631=GO_REF:0000002, GO:0003995=GO_REF:0000002, GO:0008206=Reactome:REACT_11040, GO:0033540=Reactome:REACT_17017, GO:0044255=Reactome:REACT_16957, GO:0005777=GO_REF:0000002} Q99424 Peroxisomal acyl-coenzyme A oxidase 2 protein 20130213 {GO:0016402=TAS, GO:0006635=IEA, GO:0005782=TAS, GO:0006699=TAS, GO:0033791=IEA, GO:0050660=IEA, GO:0005102=IPI, GO:0044281=TAS, GO:0003997=TAS, GO:0006631=IEA, GO:0003995=IEA, GO:0008206=TAS, GO:0033540=TAS, GO:0044255=TAS, GO:0005777=IEA} bile acid biosynthetic process, bile acid metabolic process, cellular lipid metabolic process, fatty acid beta-oxidation, fatty acid beta-oxidation using acyl-CoA oxidase, fatty acid metabolic process, small molecule metabolic process peroxisomal matrix, peroxisome 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanoyl-CoA 24-hydroxylase activity, acyl-CoA dehydrogenase activity, acyl-CoA oxidase activity, flavin adenine dinucleotide binding, pristanoyl-CoA oxidase activity, receptor binding Human ACOX3 Reactome UniProtKB {GO:0005739=GO_REF:0000019, GO:0016402=Reactome:REACT_16962, GO:0005782=Reactome:REACT_16962, GO:0050660=GO_REF:0000002, GO:0005102=PMID:20178365, GO:0006631=GO_REF:0000002, GO:0003997=GO_REF:0000002, GO:0003995=GO_REF:0000002, GO:0044281=Reactome:REACT_111217, GO:0033540=Reactome:REACT_17017, GO:0044255=Reactome:REACT_16957, GO:0005777=GO_REF:0000002} O15254 Peroxisomal acyl-coenzyme A oxidase 3 protein 20130213 {GO:0005739=IEA, GO:0016402=TAS, GO:0005782=TAS, GO:0050660=IEA, GO:0005102=IPI, GO:0006631=IEA, GO:0003997=IEA, GO:0003995=IEA, GO:0044281=TAS, GO:0033540=TAS, GO:0044255=TAS, GO:0005777=IEA} cellular lipid metabolic process, fatty acid beta-oxidation using acyl-CoA oxidase, fatty acid metabolic process, small molecule metabolic process mitochondrion, peroxisomal matrix, peroxisome acyl-CoA dehydrogenase activity, acyl-CoA oxidase activity, flavin adenine dinucleotide binding, pristanoyl-CoA oxidase activity, receptor binding Human ACOXL BHF-UCL UniProtKB {GO:0003674=GO_REF:0000015, GO:0008150=GO_REF:0000015, GO:0006635=GO_REF:0000002, GO:0050660=GO_REF:0000002, GO:0006631=GO_REF:0000002, GO:0003997=GO_REF:0000002, GO:0003995=GO_REF:0000002, GO:0005575=GO_REF:0000015, GO:0016627=GO_REF:0000002, GO:0005777=GO_REF:0000002} Q9NUZ1 Acyl-coenzyme A oxidase-like protein protein 20120516 {GO:0003674=ND, GO:0008150=ND, GO:0006635=IEA, GO:0050660=IEA, GO:0006631=IEA, GO:0003997=IEA, GO:0003995=IEA, GO:0005575=ND, GO:0016627=IEA, GO:0005777=IEA} biological_process, fatty acid beta-oxidation, fatty acid metabolic process cellular_component, peroxisome acyl-CoA dehydrogenase activity, acyl-CoA oxidase activity, flavin adenine dinucleotide binding, molecular_function, oxidoreductase activity, acting on the CH-CH group of donors Human ACP1 HPA UniProtKB {GO:0005515=PMID:9499402, GO:0043005=GO_REF:0000019, GO:0005737=GO_REF:0000052, GO:0017124=GO_REF:0000019, GO:0003993=GO_REF:0000003, GO:0009898=PMID:10940933, GO:0007268=GO_REF:0000019, GO:0005634=GO_REF:0000052, GO:0004725=GO_REF:0000002, GO:0004726=GO_REF:0000002} P24666 Low molecular weight phosphotyrosine protein phosphatase protein 20090616 {GO:0005515=IPI, GO:0043005=IEA, GO:0005737=IDA, GO:0017124=IEA, GO:0003993=IEA, GO:0009898=IDA, GO:0007268=IEA, GO:0005634=IDA, GO:0004725=IEA, GO:0004726=IEA} synaptic transmission cytoplasm, internal side of plasma membrane, neuron projection, nucleus SH3 domain binding, acid phosphatase activity, non-membrane spanning protein tyrosine phosphatase activity, protein binding, protein tyrosine phosphatase activity Human ACP2 MGI UniProtKB {GO:0001501=GO_REF:0000019, GO:0003993=GO_REF:0000003, GO:0016021=GO_REF:0000037, GO:0005765=GO_REF:0000039, GO:0007040=GO_REF:0000019, GO:0005764=PMID:3160696, GO:0043202=GO_REF:0000039} P11117 Lysosomal acid phosphatase protein 20091111 {GO:0001501=IEA, GO:0003993=IEA, GO:0016021=IEA, GO:0005765=IEA, GO:0007040=IEA, GO:0005764=IDA, GO:0043202=IEA} lysosome organization, skeletal system development integral to membrane, lysosomal lumen, lysosomal membrane, lysosome acid phosphatase activity Human ACP5 Reactome UniProtKB {GO:0006771=Reactome:REACT_11070, GO:0016787=GO_REF:0000002, GO:0006766=Reactome:REACT_11193, GO:0003993=Reactome:REACT_11171, GO:0006767=Reactome:REACT_11238, GO:0044281=Reactome:REACT_111217, GO:0016021=PMID:2338077, GO:0005764=GO_REF:0000039, GO:0008198=PMID:15993892, GO:0005829=Reactome:REACT_11171, GO:0008199=PMID:15993892} P13686 Tartrate-resistant acid phosphatase type 5 protein 20071129 {GO:0006771=TAS, GO:0016787=IEA, GO:0006766=TAS, GO:0003993=TAS, GO:0006767=TAS, GO:0044281=TAS, GO:0016021=TAS, GO:0005764=IEA, GO:0008198=IDA, GO:0005829=TAS, GO:0008199=IDA} riboflavin metabolic process, small molecule metabolic process, vitamin metabolic process, water-soluble vitamin metabolic process cytosol, integral to membrane, lysosome acid phosphatase activity, ferric iron binding, ferrous iron binding, hydrolase activity Human ACP6 MGI UniProtKB {GO:0006629=PMID:10506173, GO:0005739=GO_REF:0000019, GO:0005737=PMID:12010880, GO:0003993=GO_REF:0000003, GO:0005576=GO_REF:0000039} Q9NPH0 Lysophosphatidic acid phosphatase type 6 protein 20121231 {GO:0006629=TAS, GO:0005739=IEA, GO:0005737=IDA, GO:0003993=IEA, GO:0005576=IEA} lipid metabolic process cytoplasm, extracellular region, mitochondrion acid phosphatase activity Human ACPL2 UniProtKB UniProtKB {GO:0003993=GO_REF:0000003, GO:0005576=GO_REF:0000039} Q8TE99 Acid phosphatase-like protein 2 protein 20130413 {GO:0003993=IEA, GO:0005576=IEA} extracellular region acid phosphatase activity Human UniProtKB-SubCell:SL-0243 ACPP InterPro UniProtKB {GO:0033265=GO_REF:0000019, GO:0005886=PMID:17658863, GO:0005771=GO_REF:0000019, GO:0003993=GO_REF:0000002, GO:0031985=GO_REF:0000019, GO:0046085=GO_REF:0000019, GO:0045177=GO_REF:0000019, GO:0005576=GO_REF:0000039, GO:0030175=GO_REF:0000019, GO:0005765=GO_REF:0000039, GO:0042803=GO_REF:0000019, GO:0042802=PMID:18083097, GO:0005622=PMID:17658863, GO:0006144=GO_REF:0000019, GO:0008253=GO_REF:0000003, GO:0016021=GO_REF:0000019, GO:0030141=GO_REF:0000019, GO:0009117=GO_REF:0000019} Q5FBY0 Prostatic acid phosphatase protein 20130413 {GO:0033265=IEA, GO:0005886=IDA, GO:0005771=IEA, GO:0003993=IEA, GO:0031985=IEA, GO:0046085=IEA, GO:0045177=IEA, GO:0005576=IEA, GO:0030175=IEA, GO:0005765=IEA, GO:0042803=IEA, GO:0042802=IPI, GO:0005622=IDA, GO:0006144=IEA, GO:0008253=IEA, GO:0016021=IEA, GO:0030141=IEA, GO:0009117=IEA} adenosine metabolic process, nucleotide metabolic process, purine nucleobase metabolic process Golgi cisterna, apical part of cell, extracellular region, filopodium, integral to membrane, intracellular, lysosomal membrane, multivesicular body, plasma membrane, secretory granule 5'-nucleotidase activity, acid phosphatase activity, choline binding, identical protein binding, protein homodimerization activity Human InterPro:IPR000560 ACR HGNC UniProtKB {GO:0005515=PMID:15950651, GO:0043159=PMID:12398221, GO:0004252=PMID:6802470, GO:0005507=PMID:6815104, GO:0005798=GO_REF:0000019, GO:0042806=GO_REF:0000024, GO:0007339=GO_REF:0000019, GO:0048545=GO_REF:0000019, GO:0003677=PMID:1937464, GO:0005537=PMID:15950652, GO:0007338=GO_REF:0000024, GO:0009607=GO_REF:0000019, GO:0007190=PMID:3880736, GO:0043234=PMID:7521127, GO:0004040=GO_REF:0000024, GO:0002077=PMID:10418103, GO:0008144=GO_REF:0000024, GO:0006508=GO_REF:0000002, GO:0007341=PMID:10369396, GO:0008270=PMID:6815104, GO:0007340=PMID:2550339} P10323 Acrosin protein 20060428 {GO:0005515=IPI, GO:0043159=TAS, GO:0004252=IDA, GO:0005507=NAS, GO:0005798=IEA, GO:0042806=ISS, GO:0007339=IEA, GO:0048545=IEA, GO:0003677=NAS, GO:0005537=IDA, GO:0007338=ISS, GO:0009607=IEA, GO:0007190=IDA, GO:0043234=IDA, GO:0004040=ISS, GO:0002077=NAS, GO:0008144=ISS, GO:0006508=IEA, GO:0007341=IDA, GO:0008270=NAS, GO:0007340=IMP} acrosome matrix dispersal, acrosome reaction, activation of adenylate cyclase activity, binding of sperm to zona pellucida, penetration of zona pellucida, proteolysis, response to biotic stimulus, response to steroid hormone stimulus, single fertilization Golgi-associated vesicle, acrosomal matrix, protein complex DNA binding, amidase activity, copper ion binding, drug binding, fucose binding, mannose binding, protein binding, serine-type endopeptidase activity, zinc ion binding Human ACRBP UniProtKB UniProtKB {GO:0003674=GO_REF:0000015, GO:0008150=GO_REF:0000015, GO:0001669=GO_REF:0000039, GO:0005576=GO_REF:0000039, GO:0005575=GO_REF:0000015} Q8NEB7 Acrosin-binding protein protein 20061114 {GO:0003674=ND, GO:0008150=ND, GO:0001669=IEA, GO:0005576=IEA, GO:0005575=ND} biological_process acrosomal vesicle, cellular_component, extracellular region molecular_function Human ACSBG1 HGNC UniProtKB {GO:0000038=PMID:10954726, GO:0001676=PMID:10954726, GO:0005737=PMID:10954726, GO:0001552=GO_REF:0000019, GO:0005783=GO_REF:0000039, GO:0042552=PMID:10954726, GO:0016023=GO_REF:0000039, GO:0051384=GO_REF:0000019, GO:0031957=PMID:10954726, GO:0003824=GO_REF:0000002, GO:0005524=GO_REF:0000037, GO:0004467=PMID:10954726} Q96GR2 Long-chain-fatty-acid--CoA ligase ACSBG1 protein 20090803 {GO:0000038=IDA, GO:0001676=IDA, GO:0005737=IDA, GO:0001552=IEA, GO:0005783=IEA, GO:0042552=NAS, GO:0016023=IEA, GO:0051384=IEA, GO:0031957=IDA, GO:0003824=IEA, GO:0005524=IEA, GO:0004467=IDA} long-chain fatty acid metabolic process, myelination, ovarian follicle atresia, response to glucocorticoid stimulus, very long-chain fatty acid metabolic process cytoplasm, cytoplasmic membrane-bounded vesicle, endoplasmic reticulum ATP binding, catalytic activity, long-chain fatty acid-CoA ligase activity, very long-chain fatty acid-CoA ligase activity Human ACSBG2 GOC UniProtKB {GO:0047617=PMID:16762313, GO:0005739=PMID:16762313, GO:0001676=PMID:16371355, GO:0005737=GO_REF:0000052, GO:0016020=GO_REF:0000039, GO:0006631=PMID:16762313, GO:0007275=GO_REF:0000037, GO:0007283=GO_REF:0000037, GO:0003824=GO_REF:0000002, GO:0005524=GO_REF:0000037, GO:0030154=GO_REF:0000037, GO:0004467=PMID:16371355} Q5FVE4 Long-chain-fatty-acid--CoA ligase ACSBG2 protein 20130413 {GO:0047617=IDA, GO:0005739=IDA, GO:0001676=IDA, GO:0005737=IDA, GO:0016020=IEA, GO:0006631=IDA, GO:0007275=IEA, GO:0007283=IEA, GO:0003824=IEA, GO:0005524=IEA, GO:0030154=IEA, GO:0004467=IDA} cell differentiation, fatty acid metabolic process, long-chain fatty acid metabolic process, multicellular organismal development, spermatogenesis cytoplasm, membrane, mitochondrion ATP binding, acyl-CoA hydrolase activity, catalytic activity, long-chain fatty acid-CoA ligase activity Human ACSF2 UniProtKB UniProtKB {GO:0005739=GO_REF:0000039, GO:0016874=GO_REF:0000037, GO:0006631=GO_REF:0000037, GO:0003824=GO_REF:0000002, GO:0005524=GO_REF:0000037} Q96CM8 Acyl-CoA synthetase family member 2, mitochondrial protein 20130413 {GO:0005739=IEA, GO:0016874=IEA, GO:0006631=IEA, GO:0003824=IEA, GO:0005524=IEA} fatty acid metabolic process mitochondrion ATP binding, catalytic activity, ligase activity Human UniProtKB-SubCell:SL-0173 ACSF3 UniProtKB UniProtKB {GO:0005739=PMID:21846720, GO:0090409=PMID:21642549, GO:0006631=PMID:17762044, GO:0006633=PMID:21846720, GO:0090410=PMID:21642549, GO:0003824=GO_REF:0000002, GO:0016878=PMID:17762044, GO:0005524=GO_REF:0000037} Q4G176 Acyl-CoA synthetase family member 3, mitochondrial protein 20120112 {GO:0005739=IDA, GO:0090409=IDA, GO:0006631=IDA, GO:0006633=IDA, GO:0090410=IDA, GO:0003824=IEA, GO:0016878=IDA, GO:0005524=IEA} fatty acid biosynthetic process, fatty acid metabolic process, malonate catabolic process mitochondrion ATP binding, acid-thiol ligase activity, catalytic activity, malonyl-CoA synthetase activity Human ACSL1 Reactome UniProtKB {GO:0014070=GO_REF:0000019, GO:0001676=PMID:22022213, GO:0005886=GO_REF:0000019, GO:0071902=GO_REF:0000019, GO:0033211=GO_REF:0000019, GO:0005783=GO_REF:0000019, GO:0016874=GO_REF:0000038, GO:0005741=Reactome:REACT_115978, GO:0044281=Reactome:REACT_111217, GO:0035338=Reactome:REACT_1319, GO:0003824=GO_REF:0000002, GO:0005739=PMID:22022213, GO:0019432=Reactome:REACT_1190, GO:0044539=PMID:22022213, GO:0044255=Reactome:REACT_22279, GO:0005778=GO_REF:0000039, GO:0008610=PMID:21242590, GO:0007584=GO_REF:0000019, GO:0042493=GO_REF:0000019, GO:0042178=GO_REF:0000019, GO:0034201=GO_REF:0000019, GO:0036109=Reactome:REACT_121147, GO:0005524=GO_REF:0000037, GO:0004467=Reactome:REACT_121204, GO:0033559=Reactome:REACT_121284, GO:0043651=Reactome:REACT_121100, GO:0005789=Reactome:REACT_121204, GO:0006641=GO_REF:0000019, GO:0015908=GO_REF:0000019, GO:0016021=GO_REF:0000037} P33121 Long-chain-fatty-acid--CoA ligase 1 protein 20130213 {GO:0014070=IEA, GO:0001676=IDA, GO:0005886=IEA, GO:0071902=IEA, GO:0033211=IEA, GO:0005783=IEA, GO:0016874=IEA, GO:0005741=TAS, GO:0044281=TAS, GO:0035338=TAS, GO:0003824=IEA, GO:0005739=IDA, GO:0019432=TAS, GO:0044539=IDA, GO:0044255=TAS, GO:0005778=IEA, GO:0008610=IDA, GO:0007584=IEA, GO:0042493=IEA, GO:0042178=IEA, GO:0034201=IEA, GO:0036109=TAS, GO:0005524=IEA, GO:0004467=TAS, GO:0033559=TAS, GO:0043651=TAS, GO:0005789=TAS, GO:0006641=IEA, GO:0015908=IEA, GO:0016021=IEA} adiponectin-mediated signaling pathway, alpha-linolenic acid metabolic process, cellular lipid metabolic process, fatty acid transport, linoleic acid metabolic process, lipid biosynthetic process, long-chain fatty acid import, long-chain fatty acid metabolic process, long-chain fatty-acyl-CoA biosynthetic process, positive regulation of protein serine/threonine kinase activity, response to drug, response to nutrient, response to oleic acid, response to organic cyclic compound, small molecule metabolic process, triglyceride biosynthetic process, triglyceride metabolic process, unsaturated fatty acid metabolic process, xenobiotic catabolic process endoplasmic reticulum, endoplasmic reticulum membrane, integral to membrane, mitochondrial outer membrane, mitochondrion, peroxisomal membrane, plasma membrane ATP binding, catalytic activity, ligase activity, long-chain fatty acid-CoA ligase activity Human ACSL3 UniProtKB UniProtKB {GO:0014070=GO_REF:0000019, GO:0048471=PMID:20605918, GO:0005794=PMID:20605918, GO:0019901=PMID:20605918, GO:0005783=PMID:20605918, GO:0007584=GO_REF:0000019, GO:0019904=PMID:20605918, GO:0005741=GO_REF:0000039, GO:0034379=PMID:18003621, GO:0003824=GO_REF:0000002, GO:0005524=GO_REF:0000037, GO:2001247=PMID:18003621, GO:0004467=GO_REF:0000019, GO:0007420=GO_REF:0000019, GO:0005789=GO_REF:0000039, GO:0006633=GO_REF:0000019, GO:0016021=GO_REF:0000037, GO:0044539=PMID:20219900, GO:0005778=GO_REF:0000039} O95573 Long-chain-fatty-acid--CoA ligase 3 protein 20121022 {GO:0014070=IEA, GO:0048471=IDA, GO:0005794=IDA, GO:0019901=IPI, GO:0005783=IDA, GO:0007584=IEA, GO:0019904=IPI, GO:0005741=IEA, GO:0034379=IMP, GO:0003824=IEA, GO:0005524=IEA, GO:2001247=IMP, GO:0004467=IEA, GO:0007420=IEA, GO:0005789=IEA, GO:0006633=IEA, GO:0016021=IEA, GO:0044539=IDA, GO:0005778=IEA} brain development, fatty acid biosynthetic process, long-chain fatty acid import, positive regulation of phosphatidylcholine biosynthetic process, response to nutrient, response to organic cyclic compound, very-low-density lipoprotein particle assembly Golgi apparatus, endoplasmic reticulum, endoplasmic reticulum membrane, integral to membrane, mitochondrial outer membrane, perinuclear region of cytoplasm, peroxisomal membrane ATP binding, catalytic activity, long-chain fatty acid-CoA ligase activity, protein domain specific binding, protein kinase binding Human ACSL4 Reactome UniProtKB {GO:0006629=PMID:9598324, GO:0047676=PMID:9598324, GO:0031966=GO_REF:0000019, GO:0007584=GO_REF:0000019, GO:0060136=GO_REF:0000019, GO:0005741=GO_REF:0000039, GO:0044281=Reactome:REACT_111217, GO:0035338=Reactome:REACT_1319, GO:0003824=GO_REF:0000002, GO:0005524=GO_REF:0000037, GO:0004467=PMID:10669417, GO:0005737=PMID:11889465, GO:0019432=Reactome:REACT_1190, GO:0005789=Reactome:REACT_22376, GO:0043025=GO_REF:0000019, GO:0006641=GO_REF:0000019, GO:0060996=GO_REF:0000019, GO:0070672=GO_REF:0000019, GO:0015908=GO_REF:0000019, GO:0016021=GO_REF:0000037, GO:0044255=Reactome:REACT_22279, GO:0005778=GO_REF:0000039, GO:0005777=GO_REF:0000019} O60488 Long-chain-fatty-acid--CoA ligase 4 protein 20130301 {GO:0006629=IDA, GO:0047676=IDA, GO:0031966=IEA, GO:0007584=IEA, GO:0060136=IEA, GO:0005741=IEA, GO:0044281=TAS, GO:0035338=TAS, GO:0003824=IEA, GO:0005524=IEA, GO:0004467=IDA, GO:0005737=IDA, GO:0019432=TAS, GO:0005789=TAS, GO:0043025=IEA, GO:0006641=IEA, GO:0060996=IEA, GO:0070672=IEA, GO:0015908=IEA, GO:0016021=IEA, GO:0044255=TAS, GO:0005778=IEA, GO:0005777=IEA} cellular lipid metabolic process, dendritic spine development, embryonic process involved in female pregnancy, fatty acid transport, lipid metabolic process, long-chain fatty-acyl-CoA biosynthetic process, response to interleukin-15, response to nutrient, small molecule metabolic process, triglyceride biosynthetic process, triglyceride metabolic process cytoplasm, endoplasmic reticulum membrane, integral to membrane, mitochondrial membrane, mitochondrial outer membrane, neuronal cell body, peroxisomal membrane, peroxisome ATP binding, arachidonate-CoA ligase activity, catalytic activity, long-chain fatty acid-CoA ligase activity Human ACSL5 Reactome UniProtKB {GO:0016874=GO_REF:0000038, GO:0019432=Reactome:REACT_1190, GO:0005789=Reactome:REACT_22410, GO:0005743=GO_REF:0000019, GO:0005741=GO_REF:0000039, GO:0044281=Reactome:REACT_111217, GO:0035338=Reactome:REACT_1319, GO:0016021=GO_REF:0000037, GO:0005524=GO_REF:0000037, GO:0044255=Reactome:REACT_22279, GO:0004467=GO_REF:0000003} Q9ULC5 Long-chain-fatty-acid--CoA ligase 5 protein 20130301 {GO:0016874=IEA, GO:0019432=TAS, GO:0005789=TAS, GO:0005743=IEA, GO:0005741=IEA, GO:0044281=TAS, GO:0035338=TAS, GO:0016021=IEA, GO:0005524=IEA, GO:0044255=TAS, GO:0004467=IEA} cellular lipid metabolic process, long-chain fatty-acyl-CoA biosynthetic process, small molecule metabolic process, triglyceride biosynthetic process endoplasmic reticulum membrane, integral to membrane, mitochondrial inner membrane, mitochondrial outer membrane ATP binding, ligase activity, long-chain fatty acid-CoA ligase activity Human ACSL6 Reactome UniProtKB {GO:0005886=PMID:10548543, GO:0005634=GO_REF:0000019, GO:0005741=GO_REF:0000039, GO:0044281=Reactome:REACT_111217, GO:0035338=Reactome:REACT_1319, GO:0003824=GO_REF:0000002, GO:0042803=PMID:20429931, GO:0007405=GO_REF:0000019, GO:0005739=GO_REF:0000019, GO:0048666=GO_REF:0000019, GO:0019432=Reactome:REACT_1190, GO:0044255=Reactome:REACT_22279, GO:0005778=GO_REF:0000039, GO:0001666=GO_REF:0000019, GO:0006637=PMID:10548543, GO:0032869=GO_REF:0000019, GO:0010867=GO_REF:0000019, GO:0007584=GO_REF:0000019, GO:0010747=GO_REF:0000019, GO:0008654=GO_REF:0000019, GO:0048545=GO_REF:0000019, GO:0005524=GO_REF:0000037, GO:0004467=PMID:10548543, GO:0009629=GO_REF:0000019, GO:0010976=GO_REF:0000019, GO:0005789=Reactome:REACT_22247, GO:0006641=GO_REF:0000019, GO:0015908=GO_REF:0000019, GO:0016021=GO_REF:0000037} Q9UKU0 Long-chain-fatty-acid--CoA ligase 6 protein 20130301 {GO:0005886=NAS, GO:0005634=IEA, GO:0005741=IEA, GO:0044281=TAS, GO:0035338=TAS, GO:0003824=IEA, GO:0042803=IDA, GO:0007405=IEA, GO:0005739=IEA, GO:0048666=IEA, GO:0019432=TAS, GO:0044255=TAS, GO:0005778=IEA, GO:0001666=IEA, GO:0006637=NAS, GO:0032869=IEA, GO:0010867=IEA, GO:0007584=IEA, GO:0010747=IEA, GO:0008654=IEA, GO:0048545=IEA, GO:0005524=IEA, GO:0004467=NAS, GO:0009629=IEA, GO:0010976=IEA, GO:0005789=TAS, GO:0006641=IEA, GO:0015908=IEA, GO:0016021=IEA} acyl-CoA metabolic process, cellular lipid metabolic process, cellular response to insulin stimulus, fatty acid transport, long-chain fatty-acyl-CoA biosynthetic process, neuroblast proliferation, neuron development, phospholipid biosynthetic process, positive regulation of neuron projection development, positive regulation of plasma membrane long-chain fatty acid transport, positive regulation of triglyceride biosynthetic process, response to gravity, response to hypoxia, response to nutrient, response to steroid hormone stimulus, small molecule metabolic process, triglyceride biosynthetic process, triglyceride metabolic process endoplasmic reticulum membrane, integral to membrane, mitochondrial outer membrane, mitochondrion, nucleus, peroxisomal membrane, plasma membrane ATP binding, catalytic activity, long-chain fatty acid-CoA ligase activity, protein homodimerization activity Human ACSM1 BHF-UCL UniProtKB {GO:0042632=PMID:15361761, GO:0019395=PMID:11470804, GO:0006805=Reactome:REACT_13433, GO:0044281=Reactome:REACT_111217, GO:0018874=PMID:11470804, GO:0003824=GO_REF:0000002, GO:0005525=GO_REF:0000037, GO:0005524=GO_REF:0000037, GO:0046872=GO_REF:0000037, GO:0047760=PMID:11470804, GO:0005739=GO_REF:0000019, GO:0015645=GO_REF:0000019, GO:0005759=Reactome:REACT_6972, GO:0006633=GO_REF:0000019, GO:0003996=PMID:11470804, GO:0019605=PMID:11470804, GO:0015980=PMID:11470804} Q08AH1 Acyl-coenzyme A synthetase ACSM1, mitochondrial protein 20120516 {GO:0042632=NAS, GO:0019395=NAS, GO:0006805=TAS, GO:0044281=TAS, GO:0018874=NAS, GO:0003824=IEA, GO:0005525=IEA, GO:0005524=IEA, GO:0046872=IEA, GO:0047760=IDA, GO:0005739=IEA, GO:0015645=IEA, GO:0005759=TAS, GO:0006633=IEA, GO:0003996=IDA, GO:0019605=NAS, GO:0015980=NAS} benzoate metabolic process, butyrate metabolic process, cholesterol homeostasis, energy derivation by oxidation of organic compounds, fatty acid biosynthetic process, fatty acid oxidation, small molecule metabolic process, xenobiotic metabolic process mitochondrial matrix, mitochondrion ATP binding, GTP binding, acyl-CoA ligase activity, butyrate-CoA ligase activity, catalytic activity, fatty acid ligase activity, metal ion binding Human ACSM2B BHF-UCL UniProtKB {GO:0005739=PMID:19634011, GO:0003674=GO_REF:0000015, GO:0006805=Reactome:REACT_13433, GO:0005759=Reactome:REACT_6972, GO:0006631=GO_REF:0000037, GO:0044281=Reactome:REACT_111217, GO:0003824=GO_REF:0000002, GO:0005524=GO_REF:0000037, GO:0047760=GO_REF:0000003, GO:0046872=GO_REF:0000037} Q68CK6 Acyl-coenzyme A synthetase ACSM2B, mitochondrial protein 20120516 {GO:0005739=NAS, GO:0003674=ND, GO:0006805=TAS, GO:0005759=TAS, GO:0006631=IEA, GO:0044281=TAS, GO:0003824=IEA, GO:0005524=IEA, GO:0047760=IEA, GO:0046872=IEA} fatty acid metabolic process, small molecule metabolic process, xenobiotic metabolic process mitochondrial matrix, mitochondrion ATP binding, butyrate-CoA ligase activity, catalytic activity, metal ion binding, molecular_function Human ACSM3 BHF-UCL UniProtKB {GO:0042632=PMID:15361761, GO:0003674=GO_REF:0000015, GO:0015645=GO_REF:0000019, GO:0005759=GO_REF:0000039, GO:0008217=PMID:7907320, GO:0006633=GO_REF:0000019, GO:0005575=GO_REF:0000015, GO:0003824=GO_REF:0000002, GO:0005524=GO_REF:0000037, GO:0047760=GO_REF:0000003, GO:0046872=GO_REF:0000037} Q53FZ2 Acyl-coenzyme A synthetase ACSM3, mitochondrial protein 20120516 {GO:0042632=NAS, GO:0003674=ND, GO:0015645=IEA, GO:0005759=IEA, GO:0008217=NAS, GO:0006633=IEA, GO:0005575=ND, GO:0003824=IEA, GO:0005524=IEA, GO:0047760=IEA, GO:0046872=IEA} cholesterol homeostasis, fatty acid biosynthetic process, regulation of blood pressure cellular_component, mitochondrial matrix ATP binding, butyrate-CoA ligase activity, catalytic activity, fatty acid ligase activity, metal ion binding, molecular_function Human ACSM5 UniProtKB UniProtKB {GO:0005759=GO_REF:0000039, GO:0006631=GO_REF:0000037, GO:0005525=GO_REF:0000037, GO:0003824=GO_REF:0000002, GO:0005524=GO_REF:0000037, GO:0047760=GO_REF:0000003, GO:0046872=GO_REF:0000037} Q6NUN0 Acyl-coenzyme A synthetase ACSM5, mitochondrial protein 20130413 {GO:0005759=IEA, GO:0006631=IEA, GO:0005525=IEA, GO:0003824=IEA, GO:0005524=IEA, GO:0047760=IEA, GO:0046872=IEA} fatty acid metabolic process mitochondrial matrix ATP binding, GTP binding, butyrate-CoA ligase activity, catalytic activity, metal ion binding Human UniProtKB-SubCell:SL-0170 ACSS1 Reactome UniProtKB {GO:0005515=PMID:16788062, GO:0006805=Reactome:REACT_13705, GO:0016208=GO_REF:0000002, GO:0006069=Reactome:REACT_34, GO:0005759=Reactome:REACT_21284, GO:0019542=GO_REF:0000019, GO:0019427=GO_REF:0000002, GO:0019413=GO_REF:0000019, GO:0044281=Reactome:REACT_111217, GO:0003987=PMID:16788062, GO:0006085=PMID:16788062, GO:0005524=GO_REF:0000037} Q9NUB1 Acetyl-coenzyme A synthetase 2-like, mitochondrial protein 20130301 {GO:0005515=IPI, GO:0006805=TAS, GO:0016208=IEA, GO:0006069=TAS, GO:0005759=TAS, GO:0019542=IEA, GO:0019427=IEA, GO:0019413=IEA, GO:0044281=TAS, GO:0003987=IDA, GO:0006085=IDA, GO:0005524=IEA} acetate biosynthetic process, acetyl-CoA biosynthetic process, acetyl-CoA biosynthetic process from acetate, ethanol oxidation, propionate biosynthetic process, small molecule metabolic process, xenobiotic metabolic process mitochondrial matrix AMP binding, ATP binding, acetate-CoA ligase activity, protein binding Human ACSS2 HPA UniProtKB {GO:0008610=PMID:10843999, GO:0006805=Reactome:REACT_13705, GO:0016208=PMID:10843999, GO:0006069=Reactome:REACT_34, GO:0019542=GO_REF:0000019, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0044281=Reactome:REACT_111217, GO:0003824=GO_REF:0000002, GO:0006085=GO_REF:0000019, GO:0005524=GO_REF:0000037, GO:0005829=Reactome:REACT_553, GO:0043231=GO_REF:0000052, GO:0005737=GO_REF:0000052, GO:0019427=GO_REF:0000002, GO:0019413=GO_REF:0000019, GO:0003987=PMID:10843999} Q9NR19 Acetyl-coenzyme A synthetase, cytoplasmic protein 20080818 {GO:0008610=IMP, GO:0006805=TAS, GO:0016208=IC, GO:0006069=TAS, GO:0019542=IEA, GO:0005730=IDA, GO:0005634=IDA, GO:0044281=TAS, GO:0003824=IEA, GO:0006085=IEA, GO:0005524=IEA, GO:0005829=TAS, GO:0043231=IDA, GO:0005737=IDA, GO:0019427=IEA, GO:0019413=IEA, GO:0003987=IDA} acetate biosynthetic process, acetyl-CoA biosynthetic process, acetyl-CoA biosynthetic process from acetate, ethanol oxidation, lipid biosynthetic process, propionate biosynthetic process, small molecule metabolic process, xenobiotic metabolic process cytoplasm, cytosol, intracellular membrane-bounded organelle, nucleolus, nucleus AMP binding, ATP binding, acetate-CoA ligase activity, catalytic activity Human ACSS3 UniProtKB UniProtKB {GO:0005739=GO_REF:0000039, GO:0003987=GO_REF:0000003, GO:0003824=GO_REF:0000002, GO:0005524=GO_REF:0000037} Q9H6R3 Acyl-CoA synthetase short-chain family member 3, mitochondrial protein 20130413 {GO:0005739=IEA, GO:0003987=IEA, GO:0003824=IEA, GO:0005524=IEA} mitochondrion ATP binding, acetate-CoA ligase activity, catalytic activity Human UniProtKB-SubCell:SL-0173 ACTA1 UniProtKB UniProtKB {GO:0005515=PMID:12849983, GO:0030240=PMID:11333380, GO:0001725=PMID:15198992, GO:0030049=Reactome:REACT_16969, GO:0005884=PMID:12849983, GO:0009991=GO_REF:0000019, GO:0048741=GO_REF:0000024, GO:0015629=PMID:15198992, GO:0048545=GO_REF:0000019, GO:0030017=PMID:1423520, GO:0005524=GO_REF:0000038, GO:0005829=Reactome:REACT_17057, GO:0009612=GO_REF:0000019, GO:0005737=GO_REF:0000038, GO:0010226=GO_REF:0000019, GO:0006936=PMID:10508519, GO:0043531=PMID:10508519, GO:0043503=GO_REF:0000019, GO:0005865=PMID:15198992, GO:0005200=PMID:10508519, GO:0016049=GO_REF:0000019, GO:0017022=PMID:10508519, GO:0005856=GO_REF:0000038} Q5T8M8 Actin, alpha skeletal muscle protein 20130413 {GO:0005515=IPI, GO:0030240=IMP, GO:0001725=IDA, GO:0030049=TAS, GO:0005884=IDA, GO:0009991=IEA, GO:0048741=ISS, GO:0015629=IMP, GO:0048545=IEA, GO:0030017=IDA, GO:0005524=IEA, GO:0005829=TAS, GO:0009612=IEA, GO:0005737=IEA, GO:0010226=IEA, GO:0006936=TAS, GO:0043531=TAS, GO:0043503=IEA, GO:0005865=IDA, GO:0005200=TAS, GO:0016049=IEA, GO:0017022=TAS, GO:0005856=IEA} cell growth, muscle contraction, muscle filament sliding, response to extracellular stimulus, response to lithium ion, response to mechanical stimulus, response to steroid hormone stimulus, skeletal muscle fiber adaptation, skeletal muscle fiber development, skeletal muscle thin filament assembly actin cytoskeleton, actin filament, cytoplasm, cytoskeleton, cytosol, sarcomere, stress fiber, striated muscle thin filament ADP binding, ATP binding, myosin binding, protein binding, structural constituent of cytoskeleton Human UniProtKB-KW:KW-0206 ACTA2 Reactome UniProtKB {GO:0043234=PMID:18468998, GO:0005737=PMID:12355421, GO:0006936=Reactome:REACT_20558, GO:0008217=GO_REF:0000019, GO:0009615=PMID:16548883, GO:0015629=GO_REF:0000019, GO:0072144=PMID:17464107, GO:0005524=GO_REF:0000037, GO:0005829=Reactome:REACT_20663, GO:0030485=GO_REF:0000019, GO:0014829=GO_REF:0000019} P62736 Actin, aortic smooth muscle protein 20130301 {GO:0043234=IDA, GO:0005737=IDA, GO:0006936=TAS, GO:0008217=IEA, GO:0009615=IEP, GO:0015629=IEA, GO:0072144=IEP, GO:0005524=IEA, GO:0005829=TAS, GO:0030485=IEA, GO:0014829=IEA} glomerular mesangial cell development, muscle contraction, regulation of blood pressure, response to virus, vascular smooth muscle contraction actin cytoskeleton, cytoplasm, cytosol, protein complex, smooth muscle contractile fiber ATP binding Human ACTB BHF-UCL UniProtKB {GO:0050998=PMID:17502619, GO:0005515=PMID:21577206, GO:0030424=GO_REF:0000019, GO:0006928=PMID:16130169, GO:0007409=GO_REF:0000019, GO:0005829=Reactome:REACT_160291, GO:0005737=PMID:16130169, GO:0006457=Reactome:REACT_17004, GO:0007411=Reactome:REACT_18266, GO:0035267=PMID:10966108, GO:0005856=PMID:16130169, GO:0019901=GO_REF:0000019, GO:0034329=Reactome:REACT_20676, GO:0014069=GO_REF:0000019, GO:0030957=PMID:16687403, GO:0005524=GO_REF:0000037, GO:0045216=Reactome:REACT_19331, GO:0043234=GO_REF:0000019, GO:0070688=PMID:19377461, GO:0007596=Reactome:REACT_604, GO:0045087=Reactome:REACT_6802, GO:0030529=PMID:17289661, GO:0005200=PMID:6202424, GO:0051084=Reactome:REACT_16952, GO:0030863=GO_REF:0000019, GO:0019894=PMID:18680169, GO:0038096=Reactome:REACT_160123, GO:0044267=Reactome:REACT_17015, GO:0016044=Reactome:REACT_11123, GO:0034332=Reactome:REACT_19195} P60709 Actin, cytoplasmic 1 protein 20110811 {GO:0050998=IPI, GO:0005515=IPI, GO:0030424=IEA, GO:0006928=TAS, GO:0007409=IEA, GO:0005829=TAS, GO:0005737=TAS, GO:0006457=TAS, GO:0007411=TAS, GO:0035267=IDA, GO:0005856=TAS, GO:0019901=IEA, GO:0034329=TAS, GO:0014069=IEA, GO:0030957=IPI, GO:0005524=IEA, GO:0045216=TAS, GO:0043234=IEA, GO:0070688=IDA, GO:0007596=TAS, GO:0045087=TAS, GO:0030529=IDA, GO:0005200=TAS, GO:0051084=TAS, GO:0030863=IEA, GO:0019894=IPI, GO:0038096=TAS, GO:0044267=TAS, GO:0016044=TAS, GO:0034332=TAS} 'de novo' posttranslational protein folding, Fc-gamma receptor signaling pathway involved in phagocytosis, adherens junction organization, axon guidance, axonogenesis, blood coagulation, cell junction assembly, cell-cell junction organization, cellular component movement, cellular membrane organization, cellular protein metabolic process, innate immune response, protein folding MLL5-L complex, NuA4 histone acetyltransferase complex, axon, cortical cytoskeleton, cytoplasm, cytoskeleton, cytosol, postsynaptic density, protein complex, ribonucleoprotein complex ATP binding, Tat protein binding, kinesin binding, nitric-oxide synthase binding, protein binding, protein kinase binding, structural constituent of cytoskeleton Human UniProtKB:P04608 ACTBL2 UniProtKB UniProtKB {GO:0005737=GO_REF:0000037, GO:0005856=GO_REF:0000039, GO:0005524=GO_REF:0000037} Q562R1 Beta-actin-like protein 2 protein 20130413 {GO:0005737=IEA, GO:0005856=IEA, GO:0005524=IEA} cytoplasm, cytoskeleton ATP binding Human UniProtKB-SubCell:SL-0090 ACTC1 GOC UniProtKB {GO:0030048=PMID:16611632, GO:0030240=GO_REF:0000024, GO:0060047=PMID:17947298, GO:0042643=PMID:16611632, GO:0030049=Reactome:REACT_16969, GO:0006200=PMID:17765196, GO:0042493=GO_REF:0000019, GO:0045471=GO_REF:0000019, GO:0005884=PMID:19799913, GO:0006915=GO_REF:0000024, GO:0031032=GO_REF:0000024, GO:0060048=GO_REF:0000019, GO:0030017=PMID:16288873, GO:0005524=PMID:16611632, GO:0033275=PMID:19799913, GO:0005829=Reactome:REACT_17057, GO:0005737=PMID:20962418, GO:0055003=GO_REF:0000024, GO:0017022=PMID:19799913, GO:0016887=PMID:16611632, GO:0055008=GO_REF:0000024, GO:0031674=GO_REF:0000024} P68032 Actin, alpha cardiac muscle 1 protein 20130413 {GO:0030048=IDA, GO:0030240=ISS, GO:0060047=IMP, GO:0042643=IDA, GO:0030049=TAS, GO:0006200=IDA, GO:0042493=IEA, GO:0045471=IEA, GO:0005884=IDA, GO:0006915=ISS, GO:0031032=ISS, GO:0060048=IEA, GO:0030017=IDA, GO:0005524=IDA, GO:0033275=IMP, GO:0005829=TAS, GO:0005737=IDA, GO:0055003=ISS, GO:0017022=IDA, GO:0016887=IDA, GO:0055008=ISS, GO:0031674=ISS} ATP catabolic process, actin filament-based movement, actin-myosin filament sliding, actomyosin structure organization, apoptotic process, cardiac muscle contraction, cardiac muscle tissue morphogenesis, cardiac myofibril assembly, heart contraction, muscle filament sliding, response to drug, response to ethanol, skeletal muscle thin filament assembly I band, actin filament, actomyosin, actin part, cytoplasm, cytosol, sarcomere ATP binding, ATPase activity, myosin binding Human ACTG1 IntAct UniProtKB {GO:0005515=PMID:16189514, GO:0034329=Reactome:REACT_20676, GO:0045214=GO_REF:0000019, GO:0006928=PMID:16130169, GO:0030016=GO_REF:0000019, GO:0005524=GO_REF:0000037, GO:0045216=Reactome:REACT_19331, GO:0042802=PMID:16189514, GO:0005829=Reactome:REACT_160291, GO:0005737=GO_REF:0000038, GO:0031941=GO_REF:0000019, GO:0007411=Reactome:REACT_18266, GO:0045087=Reactome:REACT_6802, GO:0005200=PMID:16130169, GO:0005856=PMID:16130169, GO:0038096=Reactome:REACT_160123, GO:0016044=Reactome:REACT_11123, GO:0034332=Reactome:REACT_19195, GO:0070062=PMID:21557262} P63261 Actin, cytoplasmic 2 protein 20130415 {GO:0005515=IPI, GO:0034329=TAS, GO:0045214=IEA, GO:0006928=TAS, GO:0030016=IEA, GO:0005524=IEA, GO:0045216=TAS, GO:0042802=IPI, GO:0005829=TAS, GO:0005737=IEA, GO:0031941=IEA, GO:0007411=TAS, GO:0045087=TAS, GO:0005200=IC, GO:0005856=TAS, GO:0038096=TAS, GO:0016044=TAS, GO:0034332=TAS, GO:0070062=IDA} Fc-gamma receptor signaling pathway involved in phagocytosis, adherens junction organization, axon guidance, cell junction assembly, cell-cell junction organization, cellular component movement, cellular membrane organization, innate immune response, sarcomere organization cytoplasm, cytoskeleton, cytosol, extracellular vesicular exosome, filamentous actin, myofibril ATP binding, identical protein binding, protein binding, structural constituent of cytoskeleton Human UniProtKB:P63261 ACTG2 Reactome UniProtKB {GO:0005737=GO_REF:0000038, GO:0006936=Reactome:REACT_20558, GO:0005856=GO_REF:0000039, GO:0005524=GO_REF:0000037, GO:0005829=Reactome:REACT_20663, GO:0071944=GO_REF:0000019} P63267 Actin, gamma-enteric smooth muscle protein 20130301 {GO:0005737=IEA, GO:0006936=TAS, GO:0005856=IEA, GO:0005524=IEA, GO:0005829=TAS, GO:0071944=IEA} muscle contraction cell periphery, cytoplasm, cytoskeleton, cytosol ATP binding Human ACTL6A BHF-UCL UniProtKB {GO:0005515=PMID:18026119, GO:0003407=PMID:18816825, GO:0006357=PMID:8804307, GO:0005886=GO_REF:0000054, GO:0003713=PMID:8804307, GO:0005634=PMID:18026119, GO:0006310=GO_REF:0000037, GO:0071564=PMID:18816825, GO:0005524=GO_REF:0000002, GO:0006351=GO_REF:0000037, GO:0007399=GO_REF:0000019, GO:0007165=PMID:9845365, GO:0031011=PMID:21303910, GO:0006281=GO_REF:0000037, GO:0016514=PMID:8804307, GO:0043967=PMID:14966270, GO:0003682=GO_REF:0000019, GO:0043968=PMID:14966270, GO:0035267=PMID:14966270, GO:0006338=PMID:18816825, GO:0040008=GO_REF:0000037} O96019 Actin-like protein 6A protein 20110811 {GO:0005515=IPI, GO:0003407=IEP, GO:0006357=NAS, GO:0005886=IDA, GO:0003713=NAS, GO:0005634=IDA, GO:0006310=IEA, GO:0071564=IDA, GO:0005524=IEA, GO:0006351=IEA, GO:0007399=IEA, GO:0007165=TAS, GO:0031011=IDA, GO:0006281=IEA, GO:0016514=IDA, GO:0043967=IDA, GO:0003682=IEA, GO:0043968=IDA, GO:0035267=IDA, GO:0006338=IC, GO:0040008=IEA} DNA recombination, DNA repair, chromatin remodeling, histone H2A acetylation, histone H4 acetylation, nervous system development, neural retina development, regulation of growth, regulation of transcription from RNA polymerase II promoter, signal transduction, transcription, DNA-dependent Ino80 complex, NuA4 histone acetyltransferase complex, SWI/SNF complex, npBAF complex, nucleus, plasma membrane ATP binding, chromatin binding, protein binding, transcription coactivator activity Human GO:0071564 ACTL6B HPA UniProtKB {GO:0071565=GO_REF:0000024, GO:0006357=PMID:8804307, GO:0016514=PMID:8804307, GO:0003713=PMID:8804307, GO:0005730=GO_REF:0000052, GO:0005200=PMID:10380635, GO:0006325=PMID:10380635, GO:0006338=PMID:11726552, GO:0005634=PMID:10380635, GO:0005524=GO_REF:0000002, GO:0006351=GO_REF:0000037, GO:0007399=GO_REF:0000019} O94805 Actin-like protein 6B protein 20111111 {GO:0071565=ISS, GO:0006357=NAS, GO:0016514=IDA, GO:0003713=NAS, GO:0005730=IDA, GO:0005200=TAS, GO:0006325=NAS, GO:0006338=IDA, GO:0005634=IDA, GO:0005524=IEA, GO:0006351=IEA, GO:0007399=IEA} chromatin organization, chromatin remodeling, nervous system development, regulation of transcription from RNA polymerase II promoter, transcription, DNA-dependent SWI/SNF complex, nBAF complex, nucleolus, nucleus ATP binding, structural constituent of cytoskeleton, transcription coactivator activity Human ACTL7A PINC UniProtKB {GO:0043234=PMID:21278383, GO:0005737=GO_REF:0000024, GO:0005794=GO_REF:0000024, GO:0005200=PMID:10373328, GO:0005856=GO_REF:0000039, GO:0001673=GO_REF:0000019} Q9Y615 Actin-like protein 7A protein 20030904 {GO:0043234=IDA, GO:0005737=ISS, GO:0005794=ISS, GO:0005200=TAS, GO:0005856=IEA, GO:0001673=IEA} Golgi apparatus, cytoplasm, cytoskeleton, male germ cell nucleus, protein complex structural constituent of cytoskeleton Human ACTL7B PINC UniProtKB {GO:0005737=GO_REF:0000019, GO:0005200=PMID:10373328, GO:0015629=PMID:10373328} Q9Y614 Actin-like protein 7B protein 20030904 {GO:0005737=IEA, GO:0005200=TAS, GO:0015629=TAS} actin cytoskeleton, cytoplasm structural constituent of cytoskeleton Human ACTL8 HPA UniProtKB {GO:0005737=GO_REF:0000052, GO:0005856=GO_REF:0000039} Q9H568 Actin-like protein 8 protein 20100326 {GO:0005737=IDA, GO:0005856=IEA} cytoplasm, cytoskeleton Human ACTN1 BHF-UCL UniProtKB {GO:0005515=PMID:16291744, GO:0030018=GO_REF:0000039, GO:0005886=GO_REF:0000039, GO:0005634=GO_REF:0000019, GO:0042995=PMID:16464232, GO:0005829=Reactome:REACT_20671, GO:0031143=PMID:1629252, GO:0005916=GO_REF:0000019, GO:0005737=PMID:16464232, GO:0051015=GO_REF:0000019, GO:0043197=GO_REF:0000019, GO:0048041=PMID:16807302, GO:0031093=Reactome:REACT_21351, GO:0051764=GO_REF:0000002, GO:0005856=GO_REF:0000039, GO:0051017=GO_REF:0000019, GO:0034329=Reactome:REACT_20676, GO:0019904=GO_REF:0000019, GO:0005509=GO_REF:0000002, GO:0030168=Reactome:REACT_798, GO:0003779=GO_REF:0000038, GO:0042981=PMID:16807302, GO:0005576=Reactome:REACT_21351, GO:0001726=GO_REF:0000039, GO:0044325=PMID:17944866, GO:0005178=PMID:7983147, GO:0007596=Reactome:REACT_604, GO:0017166=PMID:15988023, GO:0002576=Reactome:REACT_318, GO:0051271=PMID:7983147, GO:0005925=PMID:16807302} P12814 Alpha-actinin-1 protein 20120119 {GO:0005515=IPI, GO:0030018=IEA, GO:0005886=IEA, GO:0005634=IEA, GO:0042995=IDA, GO:0005829=TAS, GO:0031143=TAS, GO:0005916=IEA, GO:0005737=IDA, GO:0051015=IEA, GO:0043197=IEA, GO:0048041=IMP, GO:0031093=TAS, GO:0051764=IEA, GO:0005856=IEA, GO:0051017=IEA, GO:0034329=TAS, GO:0019904=IEA, GO:0005509=IEA, GO:0030168=TAS, GO:0003779=IEA, GO:0042981=NAS, GO:0005576=TAS, GO:0001726=IEA, GO:0044325=IPI, GO:0005178=IDA, GO:0007596=TAS, GO:0017166=IPI, GO:0002576=TAS, GO:0051271=IMP, GO:0005925=IMP} actin crosslink formation, actin filament bundle assembly, blood coagulation, cell junction assembly, focal adhesion assembly, negative regulation of cellular component movement, platelet activation, platelet degranulation, regulation of apoptotic process Z disc, cell projection, cytoplasm, cytoskeleton, cytosol, dendritic spine, extracellular region, fascia adherens, focal adhesion, nucleus, plasma membrane, platelet alpha granule lumen, pseudopodium, ruffle actin binding, actin filament binding, calcium ion binding, integrin binding, ion channel binding, protein binding, protein domain specific binding, vinculin binding Human UniProtKB:Q9P0L9 ACTN2 BHF-UCL UniProtKB {GO:0005515=PMID:11309420, GO:0008092=PMID:10427098, GO:0030018=PMID:19932097, GO:0030035=PMID:12356918, GO:0005884=PMID:1339456, GO:0043267=PMID:10812072, GO:0043268=PMID:17110593, GO:0007268=Reactome:REACT_13685, GO:0030175=PMID:12356918, GO:0051373=PMID:11699871, GO:0042802=PMID:11101506, GO:0005829=Reactome:REACT_20670, GO:0031143=PMID:1629252, GO:0030375=GO_REF:0000019, GO:0006936=GO_REF:0000019, GO:0051015=GO_REF:0000019, GO:0043197=PMID:15841212, GO:0051289=PMID:9501083, GO:0048041=PMID:16807302, GO:0042391=PMID:10812072, GO:0046983=PMID:9501083, GO:0031093=Reactome:REACT_21351, GO:0051764=GO_REF:0000002, GO:0005856=PMID:12809483, GO:0008307=PMID:1339456, GO:0007155=PMID:10656685, GO:0051017=GO_REF:0000002, GO:0030049=Reactome:REACT_16969, GO:0005509=GO_REF:0000002, GO:0030168=Reactome:REACT_798, GO:0005576=Reactome:REACT_21351, GO:0003779=GO_REF:0000038, GO:0042981=PMID:16807302, GO:0044325=PMID:10812072, GO:0031432=PMID:11846417, GO:0005178=PMID:8104223, GO:0007596=Reactome:REACT_604, GO:1901018=PMID:17110593, GO:0002576=Reactome:REACT_318, GO:0005925=PMID:16807302, GO:0070080=PMID:11846417} P35609 Alpha-actinin-2 protein 20120919 {GO:0005515=IPI, GO:0008092=IDA, GO:0030018=IDA, GO:0030035=IDA, GO:0005884=TAS, GO:0043267=IMP, GO:0043268=IDA, GO:0007268=TAS, GO:0030175=IDA, GO:0051373=IDA, GO:0042802=IPI, GO:0005829=TAS, GO:0031143=TAS, GO:0030375=IEA, GO:0006936=IEA, GO:0051015=IEA, GO:0043197=TAS, GO:0051289=IDA, GO:0048041=IMP, GO:0042391=IMP, GO:0046983=IDA, GO:0031093=TAS, GO:0051764=IEA, GO:0005856=NAS, GO:0008307=TAS, GO:0007155=TAS, GO:0051017=IEA, GO:0030049=TAS, GO:0005509=IEA, GO:0030168=TAS, GO:0005576=TAS, GO:0003779=IEA, GO:0042981=NAS, GO:0044325=IPI, GO:0031432=IPI, GO:0005178=TAS, GO:0007596=TAS, GO:1901018=IDA, GO:0002576=TAS, GO:0005925=IMP, GO:0070080=IPI} actin crosslink formation, actin filament bundle assembly, blood coagulation, cell adhesion, focal adhesion assembly, microspike assembly, muscle contraction, muscle filament sliding, negative regulation of potassium ion transport, platelet activation, platelet degranulation, positive regulation of potassium ion transmembrane transporter activity, positive regulation of potassium ion transport, protein homotetramerization, regulation of apoptotic process, regulation of membrane potential, synaptic transmission Z disc, actin filament, cytoskeleton, cytosol, dendritic spine, extracellular region, filopodium, focal adhesion, platelet alpha granule lumen, pseudopodium FATZ binding, actin binding, actin filament binding, calcium ion binding, cytoskeletal protein binding, identical protein binding, integrin binding, ion channel binding, protein binding, protein dimerization activity, structural constituent of muscle, thyroid hormone receptor coactivator activity, titin Z domain binding, titin binding Human ACTN3 BHF-UCL UniProtKB {GO:0005515=PMID:11309420, GO:0030049=Reactome:REACT_16969, GO:0005884=PMID:1339456, GO:0005509=GO_REF:0000002, GO:0003779=GO_REF:0000037, GO:0042981=PMID:16807302, GO:0042803=PMID:15841212, GO:0005829=Reactome:REACT_17057, GO:0031143=PMID:1629252, GO:0005178=PMID:8104223, GO:0048041=PMID:16807302, GO:0051764=GO_REF:0000002, GO:0008307=PMID:1339456, GO:0051017=GO_REF:0000002, GO:0005925=PMID:16807302} Q08043 Alpha-actinin-3 protein 20110808 {GO:0005515=IPI, GO:0030049=TAS, GO:0005884=TAS, GO:0005509=IEA, GO:0003779=IEA, GO:0042981=NAS, GO:0042803=TAS, GO:0005829=TAS, GO:0031143=TAS, GO:0005178=TAS, GO:0048041=IMP, GO:0051764=IEA, GO:0008307=TAS, GO:0051017=IEA, GO:0005925=IMP} actin crosslink formation, actin filament bundle assembly, focal adhesion assembly, muscle filament sliding, regulation of apoptotic process actin filament, cytosol, focal adhesion, pseudopodium actin binding, calcium ion binding, integrin binding, protein binding, protein homodimerization activity, structural constituent of muscle Human UniProtKB:Q86TC9 ACTN4 IntAct UniProtKB {GO:0005515=PMID:16944923, GO:0030018=GO_REF:0000019, GO:0048471=PMID:15619032, GO:0032417=PMID:11948184, GO:0005634=PMID:9508771, GO:0015031=GO_REF:0000037, GO:0042803=PMID:15841212, GO:0031143=PMID:1629252, GO:0005737=PMID:9508771, GO:0051015=PMID:12411747, GO:0001882=PMID:12411747, GO:0031093=Reactome:REACT_21351, GO:0051764=GO_REF:0000002, GO:0051017=GO_REF:0000019, GO:0001666=GO_REF:0000019, GO:0005509=GO_REF:0000002, GO:0048549=GO_REF:0000019, GO:0030168=Reactome:REACT_798, GO:0005576=Reactome:REACT_21351, GO:0003779=PMID:8104223, GO:0042981=PMID:16807302, GO:0043234=PMID:11948184, GO:0047485=GO_REF:0000019, GO:0005178=PMID:8104223, GO:0007596=Reactome:REACT_604, GO:0030529=PMID:17289661, GO:0002576=Reactome:REACT_318, GO:0030863=GO_REF:0000019, GO:0051271=GO_REF:0000019, GO:0051272=PMID:15048094} O43707 Alpha-actinin-4 protein 20130415 {GO:0005515=IPI, GO:0030018=IEA, GO:0048471=IDA, GO:0032417=NAS, GO:0005634=IDA, GO:0015031=IEA, GO:0042803=TAS, GO:0031143=TAS, GO:0005737=IDA, GO:0051015=IDA, GO:0001882=IDA, GO:0031093=TAS, GO:0051764=IEA, GO:0051017=IEA, GO:0001666=IEA, GO:0005509=IEA, GO:0048549=IEA, GO:0030168=TAS, GO:0005576=TAS, GO:0003779=TAS, GO:0042981=NAS, GO:0043234=IDA, GO:0047485=IEA, GO:0005178=TAS, GO:0007596=TAS, GO:0030529=IDA, GO:0002576=TAS, GO:0030863=IEA, GO:0051271=IEA, GO:0051272=IMP} actin crosslink formation, actin filament bundle assembly, blood coagulation, negative regulation of cellular component movement, platelet activation, platelet degranulation, positive regulation of cellular component movement, positive regulation of pinocytosis, positive regulation of sodium:hydrogen antiporter activity, protein transport, regulation of apoptotic process, response to hypoxia Z disc, cortical cytoskeleton, cytoplasm, extracellular region, nucleus, perinuclear region of cytoplasm, platelet alpha granule lumen, protein complex, pseudopodium, ribonucleoprotein complex actin binding, actin filament binding, calcium ion binding, integrin binding, nucleoside binding, protein N-terminus binding, protein binding, protein homodimerization activity Human UniProtKB:Q07157 ACTR10 ENSEMBL UniProtKB {GO:0005737=GO_REF:0000037, GO:0005869=GO_REF:0000019, GO:0007018=GO_REF:0000019} Q9NZ32 Actin-related protein 10 protein 20130413 {GO:0005737=IEA, GO:0005869=IEA, GO:0007018=IEA} microtubule-based movement cytoplasm, dynactin complex Human Ensembl:ENSMUSP00000021479 ACTR1A LIFEdb UniProtKB {GO:0019886=Reactome:REACT_121399, GO:0005813=PMID:21399614, GO:0005737=GO_REF:0000054, GO:0000086=Reactome:REACT_2203, GO:0005875=PMID:7696711, GO:0000278=Reactome:REACT_152, GO:0016192=PMID:1528266, GO:0005869=PMID:7696711, GO:0005856=GO_REF:0000038, GO:0005524=GO_REF:0000037, GO:0005829=Reactome:REACT_120995} P61163 Alpha-centractin protein 20100607 {GO:0019886=TAS, GO:0005813=IDA, GO:0005737=IDA, GO:0000086=TAS, GO:0005875=TAS, GO:0000278=TAS, GO:0016192=TAS, GO:0005869=TAS, GO:0005856=IEA, GO:0005524=IEA, GO:0005829=TAS} G2/M transition of mitotic cell cycle, antigen processing and presentation of exogenous peptide antigen via MHC class II, mitotic cell cycle, vesicle-mediated transport centrosome, cytoplasm, cytoskeleton, cytosol, dynactin complex, microtubule associated complex ATP binding Human ACTR1B IntAct UniProtKB {GO:0005515=PMID:12857853, GO:0019886=Reactome:REACT_121399, GO:0005737=GO_REF:0000054, GO:0005813=PMID:21399614, GO:0005869=PMID:7696711, GO:0005524=GO_REF:0000037, GO:0005829=Reactome:REACT_120995} P42025 Beta-centractin protein 20130415 {GO:0005515=IPI, GO:0019886=TAS, GO:0005737=IDA, GO:0005813=IDA, GO:0005869=TAS, GO:0005524=IEA, GO:0005829=TAS} antigen processing and presentation of exogenous peptide antigen via MHC class II centrosome, cytoplasm, cytosol, dynactin complex ATP binding, protein binding Human UniProtKB:Q9QZB7 ACTR2 Reactome UniProtKB {GO:0034314=GO_REF:0000002, GO:0005885=PMID:19641626, GO:0045087=Reactome:REACT_6802, GO:0006928=PMID:9230079, GO:0003779=GO_REF:0000037, GO:0042995=GO_REF:0000039, GO:0015629=PMID:9230079, GO:0038096=Reactome:REACT_160123, GO:0005524=GO_REF:0000037, GO:0005829=Reactome:REACT_160291} P61160 Actin-related protein 2 protein 20130213 {GO:0034314=IEA, GO:0005885=RCA, GO:0045087=TAS, GO:0006928=TAS, GO:0003779=IEA, GO:0042995=IEA, GO:0015629=TAS, GO:0038096=TAS, GO:0005524=IEA, GO:0005829=TAS} Arp2/3 complex-mediated actin nucleation, Fc-gamma receptor signaling pathway involved in phagocytosis, cellular component movement, innate immune response Arp2/3 protein complex, actin cytoskeleton, cell projection, cytosol ATP binding, actin binding Human ACTR3 IntAct UniProtKB {GO:0005515=PMID:20195357, GO:0034314=GO_REF:0000002, GO:0030056=GO_REF:0000019, GO:0005885=PMID:9230079, GO:0002102=GO_REF:0000019, GO:0051491=GO_REF:0000019, GO:0006928=PMID:9230079, GO:0015629=PMID:9230079, GO:0005829=Reactome:REACT_160291, GO:0010592=GO_REF:0000019, GO:0009743=GO_REF:0000019, GO:0046677=GO_REF:0000019, GO:0008356=GO_REF:0000019, GO:0033206=GO_REF:0000019, GO:0051321=GO_REF:0000019, GO:0003779=GO_REF:0000037, GO:0005524=GO_REF:0000037, GO:0060076=GO_REF:0000019, GO:0030027=GO_REF:0000019, GO:0051653=GO_REF:0000019, GO:0007163=GO_REF:0000019, GO:0000139=GO_REF:0000019, GO:0045666=GO_REF:0000019, GO:0045087=Reactome:REACT_6802, GO:0050775=GO_REF:0000019, GO:0060271=PMID:20393563, GO:0038096=Reactome:REACT_160123, GO:0043519=GO_REF:0000019} P61158 Actin-related protein 3 protein 20130415 {GO:0005515=IPI, GO:0034314=IEA, GO:0030056=IEA, GO:0005885=TAS, GO:0002102=IEA, GO:0051491=IEA, GO:0006928=TAS, GO:0015629=TAS, GO:0005829=TAS, GO:0010592=IEA, GO:0009743=IEA, GO:0046677=IEA, GO:0008356=IEA, GO:0033206=IEA, GO:0051321=IEA, GO:0003779=IEA, GO:0005524=IEA, GO:0060076=IEA, GO:0030027=IEA, GO:0051653=IEA, GO:0007163=IEA, GO:0000139=IEA, GO:0045666=IEA, GO:0045087=TAS, GO:0050775=IEA, GO:0060271=IMP, GO:0038096=TAS, GO:0043519=IEA} Arp2/3 complex-mediated actin nucleation, Fc-gamma receptor signaling pathway involved in phagocytosis, asymmetric cell division, cellular component movement, cilium morphogenesis, cytokinesis after meiosis, establishment or maintenance of cell polarity, innate immune response, meiotic cell cycle, positive regulation of dendrite morphogenesis, positive regulation of filopodium assembly, positive regulation of lamellipodium assembly, positive regulation of neuron differentiation, regulation of myosin II filament organization, response to antibiotic, response to carbohydrate stimulus, spindle localization Arp2/3 protein complex, Golgi membrane, actin cytoskeleton, cytosol, excitatory synapse, hemidesmosome, lamellipodium, podosome ATP binding, actin binding, protein binding Human UniProtKB:P17535 ACTR3B UniProtKB UniProtKB {GO:0034314=GO_REF:0000002, GO:0005737=GO_REF:0000037, GO:0005885=GO_REF:0000002, GO:0003779=GO_REF:0000037, GO:0042995=GO_REF:0000039, GO:0005524=GO_REF:0000037} Q9P1U1 Actin-related protein 3B protein 20130413 {GO:0034314=IEA, GO:0005737=IEA, GO:0005885=IEA, GO:0003779=IEA, GO:0042995=IEA, GO:0005524=IEA} Arp2/3 complex-mediated actin nucleation Arp2/3 protein complex, cell projection, cytoplasm ATP binding, actin binding Human UniProtKB-SubCell:SL-0280 ACTR5 IntAct UniProtKB {GO:0005515=PMID:20855601, GO:0031011=PMID:21303910, GO:0005737=PMID:19014934, GO:0006355=GO_REF:0000037, GO:0070914=PMID:20855601, GO:0005634=PMID:19014934, GO:0006310=GO_REF:0000037, GO:0005524=GO_REF:0000002, GO:0006351=GO_REF:0000037, GO:0006302=PMID:19014934} Q9H9F9 Actin-related protein 5 protein 20130415 {GO:0005515=IPI, GO:0031011=IDA, GO:0005737=IDA, GO:0006355=IEA, GO:0070914=IMP, GO:0005634=IDA, GO:0006310=IEA, GO:0005524=IEA, GO:0006351=IEA, GO:0006302=IMP} DNA recombination, UV-damage excision repair, double-strand break repair, regulation of transcription, DNA-dependent, transcription, DNA-dependent Ino80 complex, cytoplasm, nucleus ATP binding, protein binding Human UniProtKB:Q16531 ACTR6 UniProtKB UniProtKB {GO:0005737=GO_REF:0000037, GO:0005856=GO_REF:0000039} Q9GZN1 Actin-related protein 6 protein 20130413 {GO:0005737=IEA, GO:0005856=IEA} cytoplasm, cytoskeleton Human UniProtKB-SubCell:SL-0090 ACTR8 IntAct UniProtKB {GO:0005515=PMID:18163988, GO:0031011=PMID:21303910, GO:0007067=GO_REF:0000037, GO:0006355=GO_REF:0000037, GO:0006281=GO_REF:0000037, GO:0005634=PMID:18026119, GO:0006310=GO_REF:0000037, GO:0005524=GO_REF:0000037, GO:0006351=GO_REF:0000037, GO:0051301=GO_REF:0000037} Q9H981 Actin-related protein 8 protein 20130415 {GO:0005515=IPI, GO:0031011=IDA, GO:0007067=IEA, GO:0006355=IEA, GO:0006281=IEA, GO:0005634=IDA, GO:0006310=IEA, GO:0005524=IEA, GO:0006351=IEA, GO:0051301=IEA} DNA recombination, DNA repair, cell division, mitosis, regulation of transcription, DNA-dependent, transcription, DNA-dependent Ino80 complex, nucleus ATP binding, protein binding Human UniProtKB:Q9H9F9 ACVR1 BHF-UCL UniProtKB {GO:0005515=PMID:18436533, GO:0003289=PMID:19506109, GO:0001655=GO_REF:0000019, GO:0001755=GO_REF:0000019, GO:0003183=PMID:19506109, GO:0046332=PMID:12065756, GO:0007281=GO_REF:0000019, GO:0042803=PMID:18436533, GO:0007507=GO_REF:0000019, GO:0003143=PMID:19506109, GO:0004702=GO_REF:0000019, GO:0007179=PMID:8242742, GO:0009968=PMID:9884026, GO:0002526=GO_REF:0000019, GO:0001707=GO_REF:0000019, GO:0030501=PMID:18436533, GO:0032926=PMID:9884026, GO:0030509=PMID:18436533, GO:0032924=PMID:19506109, GO:0001701=GO_REF:0000019, GO:0060923=PMID:19506109, GO:0001702=GO_REF:0000019, GO:0060037=GO_REF:0000019, GO:0048641=GO_REF:0000019, GO:0071385=GO_REF:0000019, GO:0005887=PMID:8242742, GO:0048179=PMID:8242742, GO:0060389=PMID:19736306, GO:0045893=PMID:8242742, GO:0051145=GO_REF:0000019, GO:0016361=PMID:8242742, GO:0007368=GO_REF:0000019, GO:0046872=GO_REF:0000037, GO:0000082=PMID:9884026, GO:0030278=PMID:16642017, GO:0048185=PMID:8242742, GO:0045944=PMID:19506109, GO:0005025=GO_REF:0000019, GO:0050431=PMID:8242742, GO:0001569=GO_REF:0000019, GO:0043066=PMID:9884026, GO:0061445=PMID:19506109, GO:2000017=PMID:19506109, GO:0010862=PMID:19506109, GO:0045177=GO_REF:0000019, GO:0005524=PMID:12065756, GO:0045669=PMID:18436533, GO:0004674=PMID:12065756, GO:0004675=PMID:8242742, GO:0006468=PMID:19506109, GO:0017046=PMID:12702211} Q04771 Activin receptor type-1 protein 20120312 {GO:0005515=IPI, GO:0003289=IMP, GO:0001655=IEA, GO:0001755=IEA, GO:0003183=IMP, GO:0046332=IDA, GO:0007281=IEA, GO:0042803=IDA, GO:0007507=IEA, GO:0003143=IMP, GO:0004702=IEA, GO:0007179=IDA, GO:0009968=IMP, GO:0002526=IEA, GO:0001707=IEA, GO:0030501=IMP, GO:0032926=IMP, GO:0030509=IDA, GO:0032924=IDA, GO:0001701=IEA, GO:0060923=IMP, GO:0001702=IEA, GO:0060037=IEA, GO:0048641=IEA, GO:0071385=IEA, GO:0005887=IDA, GO:0048179=IDA, GO:0060389=IDA, GO:0045893=IDA, GO:0051145=IEA, GO:0016361=IDA, GO:0007368=IEA, GO:0046872=IEA, GO:0000082=IMP, GO:0030278=IMP, GO:0048185=IDA, GO:0045944=IDA, GO:0005025=IEA, GO:0050431=IDA, GO:0001569=IEA, GO:0043066=IMP, GO:0061445=IMP, GO:2000017=IDA, GO:0010862=IDA, GO:0045177=IEA, GO:0005524=IDA, GO:0045669=IMP, GO:0004674=IDA, GO:0004675=RCA, GO:0006468=IDA, GO:0017046=NAS} BMP signaling pathway, G1/S transition of mitotic cell cycle, activin receptor signaling pathway, acute inflammatory response, atrial septum primum morphogenesis, cardiac muscle cell fate commitment, cellular response to glucocorticoid stimulus, determination of left/right symmetry, embryonic heart tube morphogenesis, endocardial cushion cell fate commitment, gastrulation with mouth forming second, germ cell development, heart development, in utero embryonic development, mesoderm formation, mitral valve morphogenesis, negative regulation of activin receptor signaling pathway, negative regulation of apoptotic process, negative regulation of signal transduction, neural crest cell migration, pathway-restricted SMAD protein phosphorylation, patterning of blood vessels, pharyngeal system development, positive regulation of bone mineralization, positive regulation of determination of dorsal identity, positive regulation of osteoblast differentiation, positive regulation of pathway-restricted SMAD protein phosphorylation, positive regulation of transcription from RNA polymerase II promoter, positive regulation of transcription, DNA-dependent, protein phosphorylation, regulation of ossification, regulation of skeletal muscle tissue development, smooth muscle cell differentiation, transforming growth factor beta receptor signaling pathway, urogenital system development activin receptor complex, apical part of cell, integral to plasma membrane ATP binding, SMAD binding, activin binding, activin receptor activity, type I, metal ion binding, peptide hormone binding, protein binding, protein homodimerization activity, protein serine/threonine kinase activity, receptor signaling protein serine/threonine kinase activity, transforming growth factor beta binding, transforming growth factor beta receptor activity, type I, transmembrane receptor protein serine/threonine kinase activity Human ACVR1B BHF-UCL UniProtKB {GO:0005515=PMID:16720724, GO:0016361=PMID:8622651, GO:0030308=PMID:11117535, GO:0005886=Reactome:REACT_150345, GO:0046332=PMID:12065756, GO:0046872=GO_REF:0000037, GO:0000082=PMID:11117535, GO:0046777=PMID:18039968, GO:0019838=PMID:14517293, GO:0004702=GO_REF:0000019, GO:0048185=PMID:12665502, GO:0045944=GO_REF:0000019, GO:0018107=PMID:18039968, GO:0007178=PMID:8397373, GO:0005024=GO_REF:0000002, GO:0001942=GO_REF:0000019, GO:0031625=PMID:16720724, GO:1901165=PMID:21356369, GO:0046545=GO_REF:0000019, GO:0006355=PMID:8622651, GO:0009986=PMID:12665502, GO:0010862=GO_REF:0000019, GO:0032927=PMID:16720724, GO:0006917=PMID:9884026, GO:0007417=GO_REF:0000019, GO:0032924=PMID:9892009, GO:0001701=GO_REF:0000019, GO:0005524=PMID:12065756, GO:0007165=PMID:12665502, GO:0016020=GO_REF:0000002, GO:0045648=PMID:9032295, GO:0004674=Reactome:REACT_111058, GO:0005887=PMID:9032295, GO:0034711=PMID:7890768, GO:0004675=PMID:9032295, GO:0038092=PMID:11389842, GO:0006468=PMID:12065756, GO:0017002=PMID:12665502} P36896 Activin receptor type-1B protein 20120719 {GO:0005515=IPI, GO:0016361=TAS, GO:0030308=IDA, GO:0005886=TAS, GO:0046332=IDA, GO:0046872=IEA, GO:0000082=IDA, GO:0046777=IDA, GO:0019838=IPI, GO:0004702=IEA, GO:0048185=IDA, GO:0045944=IEA, GO:0018107=IDA, GO:0007178=TAS, GO:0005024=IEA, GO:0001942=IEA, GO:0031625=IPI, GO:1901165=IDA, GO:0046545=IEA, GO:0006355=IDA, GO:0009986=IDA, GO:0010862=IEA, GO:0032927=IDA, GO:0006917=IMP, GO:0007417=IEA, GO:0032924=IDA, GO:0001701=IEA, GO:0005524=IDA, GO:0007165=IDA, GO:0016020=IEA, GO:0045648=IDA, GO:0004674=EXP, GO:0005887=IDA, GO:0034711=IPI, GO:0004675=NAS, GO:0038092=IGI, GO:0006468=IDA, GO:0017002=IDA} G1/S transition of mitotic cell cycle, activin receptor signaling pathway, central nervous system development, development of primary female sexual characteristics, hair follicle development, in utero embryonic development, induction of apoptosis, negative regulation of cell growth, nodal signaling pathway, peptidyl-threonine phosphorylation, positive regulation of activin receptor signaling pathway, positive regulation of erythrocyte differentiation, positive regulation of pathway-restricted SMAD protein phosphorylation, positive regulation of transcription from RNA polymerase II promoter, positive regulation of trophoblast cell migration, protein autophosphorylation, protein phosphorylation, regulation of transcription, DNA-dependent, signal transduction, transmembrane receptor protein serine/threonine kinase signaling pathway cell surface, integral to plasma membrane, membrane, plasma membrane ATP binding, SMAD binding, activin binding, activin receptor activity, type I, activin-activated receptor activity, growth factor binding, inhibin binding, metal ion binding, protein binding, protein serine/threonine kinase activity, receptor signaling protein serine/threonine kinase activity, transforming growth factor beta-activated receptor activity, transmembrane receptor protein serine/threonine kinase activity, ubiquitin protein ligase binding Human ACVR1C BHF-UCL UniProtKB {GO:0016361=PMID:12063393, GO:0032868=GO_REF:0000019, GO:0005886=Reactome:REACT_150345, GO:0019915=GO_REF:0000019, GO:0042981=PMID:15531507, GO:1901383=PMID:15150278, GO:0005524=GO_REF:0000037, GO:0002021=GO_REF:0000019, GO:0046872=PMID:12063393, GO:0030154=PMID:15531507, GO:0009749=GO_REF:0000019, GO:0048179=PMID:15531507, GO:0038092=PMID:15150278, GO:0005024=GO_REF:0000002, GO:0038100=PMID:21356369, GO:0006468=PMID:12063393, GO:0046676=GO_REF:0000019} Q8NER5 Activin receptor type-1C protein 20120517 {GO:0016361=IDA, GO:0032868=IEA, GO:0005886=TAS, GO:0019915=IEA, GO:0042981=IDA, GO:1901383=IMP, GO:0005524=IEA, GO:0002021=IEA, GO:0046872=IC, GO:0030154=IDA, GO:0009749=IEA, GO:0048179=IDA, GO:0038092=IMP, GO:0005024=IEA, GO:0038100=IMP, GO:0006468=IC, GO:0046676=IEA} cell differentiation, lipid storage, negative regulation of chorionic trophoblast cell proliferation, negative regulation of insulin secretion, nodal signaling pathway, protein phosphorylation, regulation of apoptotic process, response to dietary excess, response to glucose stimulus, response to insulin stimulus activin receptor complex, plasma membrane ATP binding, activin receptor activity, type I, metal ion binding, nodal binding, transforming growth factor beta-activated receptor activity Human ACVR2A BHF-UCL UniProtKB {GO:0005515=PMID:10746731, GO:0007368=GO_REF:0000019, GO:0005886=Reactome:REACT_150345, GO:0050999=GO_REF:0000019, GO:0048706=GO_REF:0000019, GO:0034673=PMID:10746731, GO:0007283=GO_REF:0000019, GO:0009952=GO_REF:0000019, GO:0043621=GO_REF:0000019, GO:0046872=GO_REF:0000037, GO:0005737=PMID:14738881, GO:0004702=GO_REF:0000002, GO:0019838=GO_REF:0000019, GO:0048185=PMID:9032295, GO:0007178=PMID:1314589, GO:0005024=GO_REF:0000002, GO:0030510=GO_REF:0000019, GO:0030501=PMID:18436533, GO:0009986=GO_REF:0000019, GO:0032927=PMID:12665502, GO:0030509=PMID:19366699, GO:0043084=GO_REF:0000019, GO:0015026=PMID:10746731, GO:0030165=GO_REF:0000019, GO:0005524=GO_REF:0000037, GO:0001702=GO_REF:0000019, GO:0042713=GO_REF:0000019, GO:0045669=PMID:18436533, GO:0016020=GO_REF:0000002, GO:0004674=Reactome:REACT_111068, GO:0045648=PMID:9032295, GO:0005887=PMID:1314589, GO:0004675=PMID:1314589, GO:0034711=GO_REF:0000019, GO:0001934=PMID:17472960, GO:0007498=GO_REF:0000019, GO:0017002=PMID:12665502, GO:0060011=GO_REF:0000019} P27037 Activin receptor type-2A protein 20120314 {GO:0005515=IPI, GO:0007368=IEA, GO:0005886=TAS, GO:0050999=IEA, GO:0048706=IEA, GO:0034673=IDA, GO:0007283=IEA, GO:0009952=IEA, GO:0043621=IEA, GO:0046872=IEA, GO:0005737=IDA, GO:0004702=IEA, GO:0019838=IEA, GO:0048185=IPI, GO:0007178=TAS, GO:0005024=IEA, GO:0030510=IEA, GO:0030501=IMP, GO:0009986=IEA, GO:0032927=IDA, GO:0030509=IMP, GO:0043084=IEA, GO:0015026=IDA, GO:0030165=IEA, GO:0005524=IEA, GO:0001702=IEA, GO:0042713=IEA, GO:0045669=IMP, GO:0016020=IEA, GO:0004674=EXP, GO:0045648=IDA, GO:0005887=TAS, GO:0004675=TAS, GO:0034711=IEA, GO:0001934=IMP, GO:0007498=IEA, GO:0017002=IDA, GO:0060011=IEA} BMP signaling pathway, Sertoli cell proliferation, anterior/posterior pattern specification, determination of left/right symmetry, embryonic skeletal system development, gastrulation with mouth forming second, mesoderm development, penile erection, positive regulation of activin receptor signaling pathway, positive regulation of bone mineralization, positive regulation of erythrocyte differentiation, positive regulation of osteoblast differentiation, positive regulation of protein phosphorylation, regulation of BMP signaling pathway, regulation of nitric-oxide synthase activity, sperm ejaculation, spermatogenesis, transmembrane receptor protein serine/threonine kinase signaling pathway cell surface, cytoplasm, inhibin-betaglycan-ActRII complex, integral to plasma membrane, membrane, plasma membrane ATP binding, PDZ domain binding, activin binding, activin-activated receptor activity, coreceptor activity, growth factor binding, inhibin binding, metal ion binding, protein binding, protein self-association, protein serine/threonine kinase activity, receptor signaling protein serine/threonine kinase activity, transforming growth factor beta-activated receptor activity, transmembrane receptor protein serine/threonine kinase activity Human ACVR2B BHF-UCL UniProtKB {GO:0005515=PMID:9872992, GO:0007368=GO_REF:0000019, GO:0005886=Reactome:REACT_150345, GO:0030324=GO_REF:0000019, GO:0061298=GO_REF:0000024, GO:0048705=GO_REF:0000019, GO:0009952=PMID:9916847, GO:0009791=GO_REF:0000019, GO:0060836=GO_REF:0000024, GO:0046872=GO_REF:0000037, GO:0016362=PMID:8622651, GO:0007507=GO_REF:0000019, GO:0032147=GO_REF:0000019, GO:0001946=GO_REF:0000024, GO:0005737=PMID:14738881, GO:0019838=PMID:14517293, GO:0004702=GO_REF:0000002, GO:0035265=GO_REF:0000019, GO:0048185=GO_REF:0000019, GO:0007178=PMID:8161782, GO:0005024=GO_REF:0000002, GO:0042475=GO_REF:0000019, GO:0060021=GO_REF:0000019, GO:0006355=PMID:8622651, GO:0030501=PMID:18436533, GO:0009986=PMID:12493773, GO:0001822=GO_REF:0000019, GO:0030509=PMID:19903896, GO:0032927=PMID:8622651, GO:0005524=GO_REF:0000037, GO:0001702=GO_REF:0000019, GO:0009749=GO_REF:0000019, GO:0045669=PMID:18436533, GO:0007165=PMID:8622651, GO:0031016=GO_REF:0000019, GO:0004674=Reactome:REACT_111068, GO:0005887=PMID:8161782, GO:0034711=GO_REF:0000019, GO:0048617=GO_REF:0000019, GO:0007498=GO_REF:0000019, GO:0004712=GO_REF:0000019, GO:0030073=GO_REF:0000019} Q13705 Activin receptor type-2B protein 20120319 {GO:0005515=IPI, GO:0007368=IEA, GO:0005886=TAS, GO:0030324=IEA, GO:0061298=ISS, GO:0048705=IEA, GO:0009952=IMP, GO:0009791=IEA, GO:0060836=ISS, GO:0046872=IEA, GO:0016362=TAS, GO:0007507=IEA, GO:0032147=IEA, GO:0001946=ISS, GO:0005737=IDA, GO:0019838=IPI, GO:0004702=IEA, GO:0035265=IEA, GO:0048185=IEA, GO:0007178=TAS, GO:0005024=IEA, GO:0042475=IEA, GO:0060021=IEA, GO:0006355=IDA, GO:0030501=IMP, GO:0009986=IDA, GO:0001822=IEA, GO:0030509=IMP, GO:0032927=IDA, GO:0005524=IEA, GO:0001702=IEA, GO:0009749=IEA, GO:0045669=IMP, GO:0007165=IDA, GO:0031016=IEA, GO:0004674=EXP, GO:0005887=TAS, GO:0034711=IEA, GO:0048617=IEA, GO:0007498=IEA, GO:0004712=IEA, GO:0030073=IEA} BMP signaling pathway, activation of protein kinase activity, anterior/posterior pattern specification, determination of left/right symmetry, embryonic foregut morphogenesis, gastrulation with mouth forming second, heart development, insulin secretion, kidney development, lung development, lymphangiogenesis, lymphatic endothelial cell differentiation, mesoderm development, odontogenesis of dentin-containing tooth, organ growth, palate development, pancreas development, positive regulation of activin receptor signaling pathway, positive regulation of bone mineralization, positive regulation of osteoblast differentiation, post-embryonic development, regulation of transcription, DNA-dependent, response to glucose stimulus, retina vasculature development in camera-type eye, signal transduction, skeletal system morphogenesis, transmembrane receptor protein serine/threonine kinase signaling pathway cell surface, cytoplasm, integral to plasma membrane, plasma membrane ATP binding, activin binding, activin receptor activity, type II, growth factor binding, inhibin binding, metal ion binding, protein binding, protein serine/threonine kinase activity, protein serine/threonine/tyrosine kinase activity, receptor signaling protein serine/threonine kinase activity, transforming growth factor beta-activated receptor activity Human UniProtKB:P27040 ACVRL1 BHF-UCL UniProtKB {GO:0005515=PMID:18974388, GO:0030308=PMID:17068149, GO:0008015=PMID:16752392, GO:0046332=PMID:12065756, GO:0001946=GO_REF:0000024, GO:0004702=GO_REF:0000019, GO:0043025=GO_REF:0000019, GO:0007179=PMID:15702480, GO:0030336=PMID:12453878, GO:0009986=PMID:8242742, GO:0030509=PMID:19366699, GO:0001701=GO_REF:0000019, GO:0043535=PMID:20406889, GO:0010596=PMID:17068149, GO:0061154=PMID:19592636, GO:0005887=PMID:8242742, GO:0045893=PMID:12393874, GO:0045603=GO_REF:0000019, GO:0001955=PMID:20406889, GO:0043537=PMID:19592636, GO:0045602=GO_REF:0000019, GO:0016361=PMID:8242742, GO:0008285=PMID:12453878, GO:0035313=PMID:12453878, GO:0061298=GO_REF:0000024, GO:0002043=PMID:20406889, GO:0051291=GO_REF:0000019, GO:0060836=PMID:19903896, GO:0030425=GO_REF:0000019, GO:0046872=GO_REF:0000037, GO:0051895=PMID:12453878, GO:0030513=PMID:17068149, GO:0048185=PMID:8242742, GO:0005024=PMID:8242742, GO:0032332=PMID:19494318, GO:0005025=PMID:8242742, GO:0006275=PMID:20406889, GO:0050431=PMID:8242742, GO:0006355=PMID:15702480, GO:0060841=GO_REF:0000019, GO:0060840=GO_REF:0000019, GO:0001525=PMID:16752392, GO:0005524=PMID:12065756, GO:0007165=PMID:15702480, GO:0007162=PMID:12453878, GO:0004672=GO_REF:0000002, GO:0016020=GO_REF:0000002, GO:0001938=GO_REF:0000019, GO:0001974=GO_REF:0000019, GO:0004674=PMID:12065756, GO:0001937=GO_REF:0000019, GO:0004675=PMID:8242742, GO:0001936=PMID:20406889, GO:0008217=PMID:14684682, GO:0006468=PMID:12065756} P37023 Serine/threonine-protein kinase receptor R3 protein 20120314 {GO:0005515=IPI, GO:0030308=IDA, GO:0008015=IMP, GO:0046332=IDA, GO:0001946=ISS, GO:0004702=IEA, GO:0043025=IEA, GO:0007179=IDA, GO:0030336=IMP, GO:0009986=IDA, GO:0030509=IMP, GO:0001701=IEA, GO:0043535=TAS, GO:0010596=IDA, GO:0061154=IMP, GO:0005887=IDA, GO:0045893=IDA, GO:0045603=IEA, GO:0001955=TAS, GO:0043537=IMP, GO:0045602=IEA, GO:0016361=IDA, GO:0008285=IMP, GO:0035313=IMP, GO:0061298=ISS, GO:0002043=TAS, GO:0051291=IEA, GO:0060836=IMP, GO:0030425=IEA, GO:0046872=IEA, GO:0051895=IMP, GO:0030513=IDA, GO:0048185=IDA, GO:0005024=IDA, GO:0032332=TAS, GO:0005025=IDA, GO:0006275=TAS, GO:0050431=IPI, GO:0006355=IMP, GO:0060841=IEA, GO:0060840=IEA, GO:0001525=IMP, GO:0005524=IDA, GO:0007165=IDA, GO:0007162=IMP, GO:0004672=IEA, GO:0016020=IEA, GO:0001938=IEA, GO:0001974=IEA, GO:0004674=IDA, GO:0001937=IEA, GO:0004675=RCA, GO:0001936=TAS, GO:0008217=IMP, GO:0006468=IDA} BMP signaling pathway, angiogenesis, artery development, blood circulation, blood vessel endothelial cell proliferation involved in sprouting angiogenesis, blood vessel maturation, blood vessel remodeling, endothelial tube morphogenesis, in utero embryonic development, lymphangiogenesis, lymphatic endothelial cell differentiation, negative regulation of blood vessel endothelial cell migration, negative regulation of cell adhesion, negative regulation of cell growth, negative regulation of cell migration, negative regulation of cell proliferation, negative regulation of endothelial cell differentiation, negative regulation of endothelial cell migration, negative regulation of endothelial cell proliferation, negative regulation of focal adhesion assembly, positive regulation of BMP signaling pathway, positive regulation of chondrocyte differentiation, positive regulation of endothelial cell differentiation, positive regulation of endothelial cell proliferation, positive regulation of transcription, DNA-dependent, protein heterooligomerization, protein phosphorylation, regulation of DNA replication, regulation of blood pressure, regulation of blood vessel endothelial cell migration, regulation of endothelial cell proliferation, regulation of transcription, DNA-dependent, retina vasculature development in camera-type eye, signal transduction, transforming growth factor beta receptor signaling pathway, venous blood vessel development, wound healing, spreading of epidermal cells cell surface, dendrite, integral to plasma membrane, membrane, neuronal cell body ATP binding, SMAD binding, activin binding, activin receptor activity, type I, metal ion binding, protein binding, protein kinase activity, protein serine/threonine kinase activity, receptor signaling protein serine/threonine kinase activity, transforming growth factor beta binding, transforming growth factor beta receptor activity, type I, transforming growth factor beta-activated receptor activity, transmembrane receptor protein serine/threonine kinase activity Human ACY1 PINC UniProtKB {GO:0006520=GO_REF:0000002, GO:0005737=GO_REF:0000002, GO:0006508=GO_REF:0000002, GO:0004046=GO_REF:0000003, GO:0046872=GO_REF:0000037, GO:0008237=GO_REF:0000002, GO:0005829=PMID:8394326} Q03154 Aminoacylase-1 protein 20030904 {GO:0006520=IEA, GO:0005737=IEA, GO:0006508=IEA, GO:0004046=IEA, GO:0046872=IEA, GO:0008237=IEA, GO:0005829=TAS} cellular amino acid metabolic process, proteolysis cytoplasm, cytosol aminoacylase activity, metal ion binding, metallopeptidase activity Human ACY3 UniProtKB UniProtKB {GO:0016324=GO_REF:0000039, GO:0005737=GO_REF:0000039, GO:0019048=GO_REF:0000037, GO:0016788=GO_REF:0000002, GO:0004046=GO_REF:0000019, GO:0046872=GO_REF:0000037, GO:0042802=GO_REF:0000019} Q96HD9 Aspartoacylase-2 protein 20130413 {GO:0016324=IEA, GO:0005737=IEA, GO:0019048=IEA, GO:0016788=IEA, GO:0004046=IEA, GO:0046872=IEA, GO:0042802=IEA} virus-host interaction apical plasma membrane, cytoplasm aminoacylase activity, hydrolase activity, acting on ester bonds, identical protein binding, metal ion binding Human UniProtKB-SubCell:SL-0015 ACYP1 PINC UniProtKB {GO:0003998=GO_REF:0000003, GO:0006796=PMID:3026468} P07311 Acylphosphatase-1 protein 20030904 {GO:0003998=IEA, GO:0006796=TAS} phosphate-containing compound metabolic process acylphosphatase activity Human ACYP2 PINC UniProtKB {GO:0005739=GO_REF:0000019, GO:0003998=GO_REF:0000003, GO:0006796=PMID:8268218} P14621 Acylphosphatase-2 protein 20030904 {GO:0005739=IEA, GO:0003998=IEA, GO:0006796=TAS} phosphate-containing compound metabolic process mitochondrion acylphosphatase activity Human ADA HPA UniProtKB {GO:0046638=GO_REF:0000019, GO:0005515=PMID:8101391, GO:0042542=GO_REF:0000019, GO:0033089=GO_REF:0000019, GO:0046061=GO_REF:0000019, GO:0030054=GO_REF:0000039, GO:0060407=GO_REF:0000019, GO:0060205=GO_REF:0000039, GO:0005764=PMID:8452534, GO:0005615=GO_REF:0000019, GO:0048541=GO_REF:0000019, GO:0002906=GO_REF:0000019, GO:0032261=PMID:9361033, GO:0006157=GO_REF:0000019, GO:0006154=PMID:8894685, GO:0043025=GO_REF:0000019, GO:0048286=GO_REF:0000019, GO:0009986=PMID:11772392, GO:0007568=GO_REF:0000019, GO:0070244=GO_REF:0000019, GO:0043278=GO_REF:0000019, GO:0001890=GO_REF:0000019, GO:0001889=GO_REF:0000019, GO:0042110=PMID:7594462, GO:0006144=Reactome:REACT_522, GO:0001883=GO_REF:0000019, GO:0008270=GO_REF:0000024, GO:0010460=GO_REF:0000019, GO:0009897=PMID:16670267, GO:0002314=GO_REF:0000019, GO:0009168=GO_REF:0000002, GO:0005886=GO_REF:0000052, GO:0030890=GO_REF:0000019, GO:0046103=PMID:8894685, GO:0032839=GO_REF:0000019, GO:0044281=Reactome:REACT_111217, GO:0070256=GO_REF:0000019, GO:0005829=Reactome:REACT_2135, GO:0050850=GO_REF:0000019, GO:0005737=GO_REF:0000052, GO:0046111=GO_REF:0000019, GO:0004000=PMID:8894685, GO:0060169=PMID:16670267, GO:0045987=GO_REF:0000019, GO:0043101=Reactome:REACT_1923, GO:0002636=GO_REF:0000019, GO:0043103=GO_REF:0000033, GO:0007155=GO_REF:0000037, GO:0001666=PMID:16670267, GO:0001821=GO_REF:0000019, GO:0019239=GO_REF:0000002, GO:0055086=Reactome:REACT_1698, GO:0033632=PMID:11772392, GO:0048566=GO_REF:0000019, GO:0001829=GO_REF:0000019, GO:0050862=GO_REF:0000019, GO:0042323=GO_REF:0000019, GO:0016020=PMID:11999881, GO:0002686=GO_REF:0000019, GO:0050728=GO_REF:0000019} P00813 Adenosine deaminase protein 20101115 {GO:0046638=IEA, GO:0005515=IPI, GO:0042542=IEA, GO:0033089=IEA, GO:0046061=IEA, GO:0030054=IEA, GO:0060407=IEA, GO:0060205=IEA, GO:0005764=IDA, GO:0005615=IEA, GO:0048541=IEA, GO:0002906=IEA, GO:0032261=IMP, GO:0006157=IEA, GO:0006154=IDA, GO:0043025=IEA, GO:0048286=IEA, GO:0009986=IDA, GO:0007568=IEA, GO:0070244=IEA, GO:0043278=IEA, GO:0001890=IEA, GO:0001889=IEA, GO:0042110=IDA, GO:0006144=TAS, GO:0001883=IEA, GO:0008270=ISS, GO:0010460=IEA, GO:0009897=IDA, GO:0002314=IEA, GO:0009168=IEA, GO:0005886=IDA, GO:0030890=IEA, GO:0046103=IDA, GO:0032839=IEA, GO:0044281=TAS, GO:0070256=IEA, GO:0005829=TAS, GO:0050850=IEA, GO:0005737=IDA, GO:0046111=IEA, GO:0004000=IDA, GO:0060169=IDA, GO:0045987=IEA, GO:0043101=TAS, GO:0002636=IEA, GO:0043103=IBA, GO:0007155=IEA, GO:0001666=IDA, GO:0001821=IEA, GO:0019239=IEA, GO:0055086=TAS, GO:0033632=IDA, GO:0048566=IEA, GO:0001829=IEA, GO:0050862=IEA, GO:0042323=IEA, GO:0016020=IDA, GO:0002686=IEA, GO:0050728=IEA} Peyer's patch development, T cell activation, adenosine catabolic process, aging, cell adhesion, dATP catabolic process, deoxyadenosine catabolic process, embryonic digestive tract development, germinal center B cell differentiation, histamine secretion, hypoxanthine salvage, inosine biosynthetic process, liver development, lung alveolus development, negative regulation of adenosine receptor signaling pathway, negative regulation of circadian sleep/wake cycle, non-REM sleep, negative regulation of inflammatory response, negative regulation of leukocyte migration, negative regulation of mature B cell apoptotic process, negative regulation of mucus secretion, negative regulation of penile erection, negative regulation of thymocyte apoptotic process, nucleobase-containing small molecule metabolic process, placenta development, positive regulation of B cell proliferation, positive regulation of T cell differentiation in thymus, positive regulation of T cell receptor signaling pathway, positive regulation of alpha-beta T cell differentiation, positive regulation of calcium-mediated signaling, positive regulation of germinal center formation, positive regulation of heart rate, positive regulation of smooth muscle contraction, purine nucleobase metabolic process, purine nucleotide salvage, purine ribonucleoside monophosphate biosynthetic process, purine-containing compound salvage, regulation of cell-cell adhesion mediated by integrin, response to hydrogen peroxide, response to hypoxia, response to morphine, small molecule metabolic process, trophectodermal cell differentiation, xanthine biosynthetic process cell junction, cell surface, cytoplasm, cytoplasmic membrane-bounded vesicle lumen, cytosol, dendrite cytoplasm, external side of plasma membrane, extracellular space, lysosome, membrane, neuronal cell body, plasma membrane adenosine deaminase activity, deaminase activity, protein binding, purine nucleoside binding, zinc ion binding Human ADAD2 InterPro UniProtKB {GO:0003725=GO_REF:0000002, GO:0006396=GO_REF:0000002, GO:0004000=GO_REF:0000002} Q8NCV1 Adenosine deaminase domain-containing protein 2 protein 20130413 {GO:0003725=IEA, GO:0006396=IEA, GO:0004000=IEA} RNA processing adenosine deaminase activity, double-stranded RNA binding Human InterPro:IPR002466 ADAM10 BHF-UCL UniProtKB {GO:0005515=PMID:10527948, GO:0008284=PMID:18373975, GO:0017124=GO_REF:0000037, GO:0007220=Reactome:REACT_2001, GO:0005886=Reactome:REACT_160218, GO:0030307=PMID:18373975, GO:0007267=PMID:12714508, GO:0005634=GO_REF:0000024, GO:0051089=PMID:12714508, GO:0051088=PMID:18676862, GO:0042803=GO_REF:0000024, GO:0005737=GO_REF:0000024, GO:0022617=Reactome:REACT_118572, GO:0007173=Reactome:REACT_9417, GO:0007219=Reactome:REACT_118862, GO:0030198=Reactome:REACT_118779, GO:0030574=Reactome:REACT_150401, GO:0006509=PMID:19114711, GO:0030335=PMID:18373975, GO:0005794=PMID:12475894, GO:0019901=GO_REF:0000024, GO:0009986=PMID:12475894, GO:0010820=PMID:18373975, GO:0005798=PMID:12475894, GO:0005102=PMID:12176995, GO:0014069=GO_REF:0000019, GO:0001701=GO_REF:0000024, GO:0012505=GO_REF:0000039, GO:0007162=PMID:12714508, GO:0005178=PMID:8694785, GO:0004175=GO_REF:0000024, GO:0042117=PMID:11831872, GO:0007229=PMID:8694785, GO:0034612=PMID:11831872, GO:0006468=GO_REF:0000024, GO:0008270=GO_REF:0000002, GO:0016021=PMID:8694785, GO:0004222=PMID:19114711, GO:0008237=PMID:12535668} O14672 Disintegrin and metalloproteinase domain-containing protein 10 protein 20101126 {GO:0005515=IPI, GO:0008284=IMP, GO:0017124=IEA, GO:0007220=TAS, GO:0005886=TAS, GO:0030307=IMP, GO:0007267=NAS, GO:0005634=ISS, GO:0051089=IDA, GO:0051088=IMP, GO:0042803=ISS, GO:0005737=ISS, GO:0022617=TAS, GO:0007173=TAS, GO:0007219=TAS, GO:0030198=TAS, GO:0030574=TAS, GO:0006509=IDA, GO:0030335=IMP, GO:0005794=IDA, GO:0019901=ISS, GO:0009986=IDA, GO:0010820=IMP, GO:0005798=IDA, GO:0005102=NAS, GO:0014069=IEA, GO:0001701=ISS, GO:0012505=IEA, GO:0007162=IDA, GO:0005178=NAS, GO:0004175=ISS, GO:0042117=IMP, GO:0007229=NAS, GO:0034612=IDA, GO:0006468=ISS, GO:0008270=IEA, GO:0016021=NAS, GO:0004222=IMP, GO:0008237=IMP} Notch receptor processing, Notch signaling pathway, PMA-inducible membrane protein ectodomain proteolysis, cell-cell signaling, collagen catabolic process, constitutive protein ectodomain proteolysis, epidermal growth factor receptor signaling pathway, extracellular matrix disassembly, extracellular matrix organization, in utero embryonic development, integrin-mediated signaling pathway, membrane protein ectodomain proteolysis, monocyte activation, negative regulation of cell adhesion, positive regulation of T cell chemotaxis, positive regulation of cell growth, positive regulation of cell migration, positive regulation of cell proliferation, protein phosphorylation, response to tumor necrosis factor Golgi apparatus, Golgi-associated vesicle, cell surface, cytoplasm, endomembrane system, integral to membrane, nucleus, plasma membrane, postsynaptic density SH3 domain binding, endopeptidase activity, integrin binding, metalloendopeptidase activity, metallopeptidase activity, protein binding, protein homodimerization activity, protein kinase binding, receptor binding, zinc ion binding Human UniProtKB:Q9UI95 ADAM11 BHF-UCL UniProtKB {GO:0031012=PMID:22261194, GO:0005178=PMID:9693107, GO:0005886=PMID:9693107, GO:0007229=PMID:8252040, GO:0006508=GO_REF:0000002, GO:0008270=GO_REF:0000002, GO:0016021=GO_REF:0000037, GO:0004222=GO_REF:0000002, GO:0008237=PMID:9693107} O75078 Disintegrin and metalloproteinase domain-containing protein 11 protein 20120228 {GO:0031012=ISS, GO:0005178=TAS, GO:0005886=TAS, GO:0007229=TAS, GO:0006508=IEA, GO:0008270=IEA, GO:0016021=IEA, GO:0004222=IEA, GO:0008237=TAS} integrin-mediated signaling pathway, proteolysis extracellular matrix, integral to membrane, plasma membrane integrin binding, metalloendopeptidase activity, metallopeptidase activity, zinc ion binding colocalizes_with Human UniProtKB:F1RQZ7 ADAM12 UniProtKB UniProtKB {GO:0017124=PMID:15280379, GO:0005886=GO_REF:0000052, GO:0005730=GO_REF:0000052, GO:0005576=GO_REF:0000038, GO:0007520=PMID:7566181, GO:0005634=GO_REF:0000052, GO:0005739=GO_REF:0000052, GO:0007173=Reactome:REACT_9417, GO:0006508=GO_REF:0000038, GO:0008270=GO_REF:0000002, GO:0016021=GO_REF:0000037, GO:0004222=GO_REF:0000002, GO:0007155=GO_REF:0000037, GO:0008237=PMID:9417060} Q5JRP2 Disintegrin and metalloproteinase domain-containing protein 12 protein 20130413 {GO:0017124=IPI, GO:0005886=IDA, GO:0005730=IDA, GO:0005576=IEA, GO:0007520=TAS, GO:0005634=IDA, GO:0005739=IDA, GO:0007173=TAS, GO:0006508=IEA, GO:0008270=IEA, GO:0016021=IEA, GO:0004222=IEA, GO:0007155=IEA, GO:0008237=TAS} cell adhesion, epidermal growth factor receptor signaling pathway, myoblast fusion, proteolysis extracellular region, integral to membrane, mitochondrion, nucleolus, nucleus, plasma membrane SH3 domain binding, metalloendopeptidase activity, metallopeptidase activity, zinc ion binding Human UniProtKB-KW:KW-0645 ADAM15 BHF-UCL UniProtKB {GO:0005515=PMID:15280379, GO:0017124=PMID:10531379, GO:0001669=GO_REF:0000039, GO:0001525=GO_REF:0000037, GO:0042995=GO_REF:0000037, GO:0042246=GO_REF:0000019, GO:0012505=GO_REF:0000039, GO:0060317=GO_REF:0000019, GO:0005912=GO_REF:0000039, GO:0007160=PMID:9516430, GO:0030574=GO_REF:0000037, GO:0006508=GO_REF:0000037, GO:0008270=GO_REF:0000002, GO:0016021=GO_REF:0000037, GO:0004222=GO_REF:0000002, GO:0008237=PMID:12777399} Q13444 Disintegrin and metalloproteinase domain-containing protein 15 protein 20110220 {GO:0005515=IPI, GO:0017124=IPI, GO:0001669=IEA, GO:0001525=IEA, GO:0042995=IEA, GO:0042246=IEA, GO:0012505=IEA, GO:0060317=IEA, GO:0005912=IEA, GO:0007160=TAS, GO:0030574=IEA, GO:0006508=IEA, GO:0008270=IEA, GO:0016021=IEA, GO:0004222=IEA, GO:0008237=IDA} angiogenesis, cardiac epithelial to mesenchymal transition, cell-matrix adhesion, collagen catabolic process, proteolysis, tissue regeneration acrosomal vesicle, adherens junction, cell projection, endomembrane system, integral to membrane SH3 domain binding, metalloendopeptidase activity, metallopeptidase activity, protein binding, zinc ion binding Human ADAM17 BHF-UCL UniProtKB {GO:0005515=PMID:10527948, GO:0032717=PMID:16034137, GO:0033025=PMID:10433800, GO:0030307=PMID:18373975, GO:0048536=PMID:10433800, GO:0007219=GO_REF:0000037, GO:0007173=PMID:12743035, GO:0030198=Reactome:REACT_118779, GO:0030574=Reactome:REACT_150401, GO:0006508=GO_REF:0000002, GO:0032496=PMID:18383040, GO:0006509=PMID:18676862, GO:0002467=PMID:10433800, GO:0033077=PMID:10433800, GO:0030335=PMID:18373975, GO:0009986=PMID:18625725, GO:0035625=PMID:17655843, GO:0045741=PMID:18483258, GO:0032722=PMID:16034137, GO:0030165=PMID:12207026, GO:0055099=PMID:17786981, GO:0005178=PMID:14970227, GO:0005887=PMID:17786981, GO:0045121=PMID:17010968, GO:0008270=GO_REF:0000002, GO:0004222=PMID:9920899, GO:0005925=PMID:14970227, GO:0008237=PMID:12777399, GO:0005138=PMID:16034137, GO:0008284=PMID:18373975, GO:0017124=GO_REF:0000037, GO:0033627=PMID:14970227, GO:0035313=PMID:14970227, GO:0005886=Reactome:REACT_150205, GO:0031293=Reactome:REACT_13443, GO:0060397=Reactome:REACT_111133, GO:0051088=PMID:18676862, GO:0015629=PMID:17010968, GO:0005737=GO_REF:0000019, GO:0016324=PMID:16034137, GO:0022617=Reactome:REACT_118572, GO:0005911=PMID:14970227, GO:0048870=PMID:10433800, GO:0030183=PMID:10433800, GO:0007155=PMID:14970227, GO:0030511=PMID:10433800, GO:0001666=PMID:18276953, GO:0048011=Reactome:REACT_13776, GO:0002446=PMID:16034137, GO:0042493=PMID:10433800, GO:0010820=PMID:18373975, GO:0032587=PMID:14970227, GO:0002690=PMID:16034137, GO:0031659=PMID:18483258, GO:0001934=PMID:18625725, GO:0051272=PMID:10433800} P78536 Disintegrin and metalloproteinase domain-containing protein 17 protein 20110110 {GO:0005515=IPI, GO:0032717=IMP, GO:0033025=ISS, GO:0030307=IMP, GO:0048536=ISS, GO:0007219=IEA, GO:0007173=IDA, GO:0030198=TAS, GO:0030574=TAS, GO:0006508=IEA, GO:0032496=IDA, GO:0006509=IDA, GO:0002467=ISS, GO:0033077=ISS, GO:0030335=IMP, GO:0009986=IDA, GO:0035625=IMP, GO:0045741=IDA, GO:0032722=IMP, GO:0030165=IPI, GO:0055099=IDA, GO:0005178=IPI, GO:0005887=IDA, GO:0045121=IDA, GO:0008270=IEA, GO:0004222=IDA, GO:0005925=IDA, GO:0008237=IDA, GO:0005138=IPI, GO:0008284=IMP, GO:0017124=IEA, GO:0033627=IDA, GO:0035313=IEP, GO:0005886=TAS, GO:0031293=TAS, GO:0060397=TAS, GO:0051088=IMP, GO:0015629=IDA, GO:0005737=IEA, GO:0016324=IDA, GO:0022617=TAS, GO:0005911=IDA, GO:0048870=ISS, GO:0030183=ISS, GO:0007155=IDA, GO:0030511=ISS, GO:0001666=IDA, GO:0048011=TAS, GO:0002446=IC, GO:0042493=ISS, GO:0010820=IMP, GO:0032587=IDA, GO:0002690=IC, GO:0031659=IDA, GO:0001934=IMP, GO:0051272=ISS} B cell differentiation, JAK-STAT cascade involved in growth hormone signaling pathway, Notch signaling pathway, PMA-inducible membrane protein ectodomain proteolysis, T cell differentiation in thymus, cell adhesion, cell adhesion mediated by integrin, cell motility, collagen catabolic process, epidermal growth factor receptor signaling pathway, epidermal growth factor-activated receptor transactivation by G-protein coupled receptor signaling pathway, extracellular matrix disassembly, extracellular matrix organization, germinal center formation, membrane protein ectodomain proteolysis, membrane protein intracellular domain proteolysis, negative regulation of interleukin-8 production, neurotrophin TRK receptor signaling pathway, neutrophil mediated immunity, positive regulation of T cell chemotaxis, positive regulation of cell growth, positive regulation of cell migration, positive regulation of cell proliferation, positive regulation of cellular component movement, positive regulation of chemokine production, positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S, positive regulation of epidermal growth factor-activated receptor activity, positive regulation of leukocyte chemotaxis, positive regulation of protein phosphorylation, positive regulation of transforming growth factor beta receptor signaling pathway, proteolysis, regulation of mast cell apoptotic process, response to drug, response to high density lipoprotein particle stimulus, response to hypoxia, response to lipopolysaccharide, spleen development, wound healing, spreading of epidermal cells actin cytoskeleton, apical plasma membrane, cell surface, cell-cell junction, cytoplasm, focal adhesion, integral to plasma membrane, membrane raft, plasma membrane, ruffle membrane PDZ domain binding, SH3 domain binding, integrin binding, interleukin-6 receptor binding, metalloendopeptidase activity, metallopeptidase activity, protein binding, zinc ion binding Human ADAM19 ENSEMBL UniProtKB {GO:0007507=GO_REF:0000019, GO:0017124=GO_REF:0000037, GO:0006508=GO_REF:0000002, GO:0008270=GO_REF:0000002, GO:0006509=GO_REF:0000019, GO:0016021=GO_REF:0000037, GO:0004222=GO_REF:0000002} Q9H013 Disintegrin and metalloproteinase domain-containing protein 19 protein 20130413 {GO:0007507=IEA, GO:0017124=IEA, GO:0006508=IEA, GO:0008270=IEA, GO:0006509=IEA, GO:0016021=IEA, GO:0004222=IEA} heart development, membrane protein ectodomain proteolysis, proteolysis integral to membrane SH3 domain binding, metalloendopeptidase activity, zinc ion binding Human Ensembl:ENSMUSP00000011400 ADAM2 PINC UniProtKB {GO:0005178=PMID:9041139, GO:0007342=PMID:9041139, GO:0005887=PMID:9041139, GO:0007229=GO_REF:0000038, GO:0008542=GO_REF:0000019, GO:0006508=GO_REF:0000002, GO:0030534=GO_REF:0000019, GO:0008270=GO_REF:0000002, GO:0007155=GO_REF:0000019, GO:0004222=GO_REF:0000002, GO:0008237=PMID:9041139} Q99965 Disintegrin and metalloproteinase domain-containing protein 2 protein 20030904 {GO:0005178=TAS, GO:0007342=TAS, GO:0005887=TAS, GO:0007229=IEA, GO:0008542=IEA, GO:0006508=IEA, GO:0030534=IEA, GO:0008270=IEA, GO:0007155=IEA, GO:0004222=IEA, GO:0008237=TAS} adult behavior, cell adhesion, fusion of sperm to egg plasma membrane, integrin-mediated signaling pathway, proteolysis, visual learning integral to plasma membrane integrin binding, metalloendopeptidase activity, metallopeptidase activity, zinc ion binding Human ADAM20 PINC UniProtKB {GO:0007338=PMID:9469942, GO:0006508=GO_REF:0000037, GO:0008270=GO_REF:0000002, GO:0016021=GO_REF:0000037, GO:0004222=GO_REF:0000002, GO:0008237=PMID:9469942} O43506 Disintegrin and metalloproteinase domain-containing protein 20 protein 20030904 {GO:0007338=TAS, GO:0006508=IEA, GO:0008270=IEA, GO:0016021=IEA, GO:0004222=IEA, GO:0008237=TAS} proteolysis, single fertilization integral to membrane metalloendopeptidase activity, metallopeptidase activity, zinc ion binding Human ADAM22 PINC UniProtKB {GO:0005515=PMID:20463223, GO:0008344=GO_REF:0000019, GO:0007162=PMID:9693107, GO:0005178=PMID:9693107, GO:0022011=GO_REF:0000019, GO:0006508=GO_REF:0000002, GO:0005576=GO_REF:0000038, GO:0008270=GO_REF:0000002, GO:0016021=PMID:9693107, GO:0007417=PMID:9693107, GO:0007155=GO_REF:0000037, GO:0004222=GO_REF:0000002} Q9P0K1 Disintegrin and metalloproteinase domain-containing protein 22 protein 20050308 {GO:0005515=IPI, GO:0008344=IEA, GO:0007162=NAS, GO:0005178=NAS, GO:0022011=IEA, GO:0006508=IEA, GO:0005576=IEA, GO:0008270=IEA, GO:0016021=NAS, GO:0007417=TAS, GO:0007155=IEA, GO:0004222=IEA} adult locomotory behavior, cell adhesion, central nervous system development, myelination in peripheral nervous system, negative regulation of cell adhesion, proteolysis extracellular region, integral to membrane integrin binding, metalloendopeptidase activity, protein binding, zinc ion binding Human ADAM23 PINC UniProtKB {GO:0005515=PMID:20463223, GO:0005178=PMID:9693107, GO:0005887=PMID:9693107, GO:0006508=GO_REF:0000002, GO:0005576=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0007417=PMID:9693107, GO:0007155=GO_REF:0000037, GO:0004222=GO_REF:0000002, GO:0008237=PMID:9693107} O75077 Disintegrin and metalloproteinase domain-containing protein 23 protein 20030904 {GO:0005515=IPI, GO:0005178=TAS, GO:0005887=TAS, GO:0006508=IEA, GO:0005576=IEA, GO:0008270=IEA, GO:0007417=TAS, GO:0007155=IEA, GO:0004222=IEA, GO:0008237=TAS} cell adhesion, central nervous system development, proteolysis extracellular region, integral to plasma membrane integrin binding, metalloendopeptidase activity, metallopeptidase activity, protein binding, zinc ion binding Human ADAM28 BHF-UCL UniProtKB {GO:0005886=GO_REF:0000039, GO:0007229=GO_REF:0000038, GO:0006508=GO_REF:0000037, GO:0005576=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0007283=PMID:10587367, GO:0016021=GO_REF:0000037, GO:0004222=GO_REF:0000002, GO:0008237=PMID:12777399} Q9UKQ2 Disintegrin and metalloproteinase domain-containing protein 28 protein 20110220 {GO:0005886=IEA, GO:0007229=IEA, GO:0006508=IEA, GO:0005576=IEA, GO:0008270=IEA, GO:0007283=TAS, GO:0016021=IEA, GO:0004222=IEA, GO:0008237=IDA} integrin-mediated signaling pathway, proteolysis, spermatogenesis extracellular region, integral to membrane, plasma membrane metalloendopeptidase activity, metallopeptidase activity, zinc ion binding Human ADAM29 PINC UniProtKB {GO:0005887=PMID:10512762, GO:0006508=GO_REF:0000002, GO:0008270=GO_REF:0000002, GO:0007283=PMID:10512762, GO:0004222=GO_REF:0000002, GO:0008237=PMID:10512762} Q9UKF5 Disintegrin and metalloproteinase domain-containing protein 29 protein 20030904 {GO:0005887=TAS, GO:0006508=IEA, GO:0008270=IEA, GO:0007283=TAS, GO:0004222=IEA, GO:0008237=TAS} proteolysis, spermatogenesis integral to plasma membrane metalloendopeptidase activity, metallopeptidase activity, zinc ion binding Human ADAM33 UniProtKB UniProtKB {GO:0006508=PMID:11814695, GO:0008270=PMID:11814695, GO:0016021=PMID:11814695, GO:0004222=PMID:11814695} Q9BZ11 Disintegrin and metalloproteinase domain-containing protein 33 protein 20020812 {GO:0006508=NAS, GO:0008270=NAS, GO:0016021=NAS, GO:0004222=NAS} proteolysis integral to membrane metalloendopeptidase activity, zinc ion binding Human ADAM8 BHF-UCL UniProtKB {GO:0005515=PMID:12777399, GO:2000391=PMID:17548643, GO:0051897=GO_REF:0000024, GO:0033089=GO_REF:0000024, GO:0051044=PMID:15220135, GO:0005886=PMID:17548643, GO:2000418=GO_REF:0000024, GO:0035419=GO_REF:0000024, GO:2000415=GO_REF:0000024, GO:0071133=GO_REF:0000024, GO:0042581=PMID:17548643, GO:0050714=PMID:17548643, GO:0002102=PMID:15220135, GO:0032127=PMID:17548643, GO:0043621=PMID:12777399, GO:0043524=GO_REF:0000024, GO:0005737=PMID:18397961, GO:0016337=GO_REF:0000019, GO:0051092=GO_REF:0000024, GO:0006954=PMID:17548643, GO:0002675=GO_REF:0000024, GO:0045780=GO_REF:0000024, GO:0006508=GO_REF:0000037, GO:0032010=PMID:17548643, GO:0050839=PMID:12777399, GO:0022407=PMID:17548643, GO:0009986=PMID:17548643, GO:0002523=GO_REF:0000024, GO:0005509=GO_REF:0000024, GO:2000309=GO_REF:0000024, GO:0070245=GO_REF:0000024, GO:0071456=PMID:18566576, GO:0001525=GO_REF:0000024, GO:0045785=GO_REF:0000024, GO:0000902=GO_REF:0000024, GO:0010954=PMID:17548643, GO:0071065=PMID:15220135, GO:0005887=PMID:18397961, GO:0048247=GO_REF:0000024, GO:0008270=PMID:18397961, GO:0070820=PMID:17548643, GO:0004222=GO_REF:0000002, GO:0008237=PMID:12777399} P78325 Disintegrin and metalloproteinase domain-containing protein 8 protein 20110220 {GO:0005515=IPI, GO:2000391=IDA, GO:0051897=ISS, GO:0033089=ISS, GO:0051044=IDA, GO:0005886=IDA, GO:2000418=ISS, GO:0035419=ISS, GO:2000415=ISS, GO:0071133=ISS, GO:0042581=IDA, GO:0050714=IC, GO:0002102=IDA, GO:0032127=IDA, GO:0043621=TAS, GO:0043524=ISS, GO:0005737=IDA, GO:0016337=IEA, GO:0051092=ISS, GO:0006954=IDA, GO:0002675=ISS, GO:0045780=ISS, GO:0006508=IEA, GO:0032010=IDA, GO:0050839=IPI, GO:0022407=IDA, GO:0009986=IDA, GO:0002523=ISS, GO:0005509=ISS, GO:2000309=ISS, GO:0070245=ISS, GO:0071456=IDA, GO:0001525=ISS, GO:0045785=ISS, GO:0000902=ISS, GO:0010954=NAS, GO:0071065=IDA, GO:0005887=IDA, GO:0048247=ISS, GO:0008270=TAS, GO:0070820=IDA, GO:0004222=IEA, GO:0008237=IDA} activation of MAPK activity involved in innate immune response, angiogenesis, cell morphogenesis, cell-cell adhesion, cellular response to hypoxia, inflammatory response, leukocyte migration involved in inflammatory response, lymphocyte chemotaxis, negative regulation of neuron apoptotic process, positive regulation of NF-kappaB transcription factor activity, positive regulation of T cell differentiation in thymus, positive regulation of acute inflammatory response, positive regulation of bone resorption, positive regulation of cell adhesion, positive regulation of eosinophil migration, positive regulation of fibronectin-dependent thymocyte migration, positive regulation of membrane protein ectodomain proteolysis, positive regulation of neutrophil extravasation, positive regulation of protein kinase B signaling cascade, positive regulation of protein processing, positive regulation of protein secretion, positive regulation of thymocyte apoptotic process, positive regulation of tumor necrosis factor (ligand) superfamily member 11 production, proteolysis, regulation of cell-cell adhesion alpha9-beta1 integrin-ADAM8 complex, alpha9-beta1 integrin-vascular cell adhesion molecule-1 complex, cell surface, cytoplasm, dense core granule membrane, integral to plasma membrane, phagolysosome, plasma membrane, podosome, specific granule, tertiary granule calcium ion binding, cell adhesion molecule binding, metalloendopeptidase activity, metallopeptidase activity, protein binding, protein self-association, zinc ion binding Human UniProtKB:Q05910 ADAM9 BHF-UCL UniProtKB {GO:0005515=PMID:15280379, GO:0042542=PMID:17018608, GO:0051044=PMID:8647900, GO:0017124=PMID:10531379, GO:0051549=PMID:17704059, GO:0005518=PMID:15361064, GO:0051088=PMID:9920899, GO:0005615=PMID:8647900, GO:0010042=PMID:11162558, GO:0005737=GO_REF:0000019, GO:0000186=PMID:17704059, GO:0022617=Reactome:REACT_118572, GO:0030198=Reactome:REACT_118779, GO:0005080=PMID:8647900, GO:0030574=Reactome:REACT_150401, GO:0006508=GO_REF:0000002, GO:0007179=PMID:8647900, GO:0006509=PMID:22480688, GO:0007155=PMID:11162558, GO:0034241=PMID:11831872, GO:0009986=PMID:8647900, GO:0051384=PMID:8647900, GO:0033631=PMID:17704059, GO:0031233=PMID:8647900, GO:0051592=PMID:11162558, GO:0071222=PMID:22480688, GO:0005178=PMID:11162558, GO:0007160=PMID:15361064, GO:0007229=PMID:11162558, GO:0030216=PMID:17704059, GO:0042117=PMID:11831872, GO:0043236=PMID:15361064, GO:0034612=PMID:11831872, GO:0008270=GO_REF:0000002, GO:0016021=GO_REF:0000037, GO:0004222=PMID:22480688, GO:0008237=PMID:12535668} Q13443 Disintegrin and metalloproteinase domain-containing protein 9 protein 20120704 {GO:0005515=IPI, GO:0042542=IMP, GO:0051044=ISS, GO:0017124=IPI, GO:0051549=IMP, GO:0005518=IMP, GO:0051088=TAS, GO:0005615=ISS, GO:0010042=IMP, GO:0005737=IEA, GO:0000186=IDA, GO:0022617=TAS, GO:0030198=TAS, GO:0005080=ISS, GO:0030574=TAS, GO:0006508=IEA, GO:0007179=ISS, GO:0006509=IMP, GO:0007155=IMP, GO:0034241=IMP, GO:0009986=ISS, GO:0051384=ISS, GO:0033631=IEP, GO:0031233=ISS, GO:0051592=IMP, GO:0071222=IMP, GO:0005178=IC, GO:0007160=IMP, GO:0007229=IC, GO:0030216=IEP, GO:0042117=IMP, GO:0043236=IMP, GO:0034612=IDA, GO:0008270=IEA, GO:0016021=IEA, GO:0004222=IMP, GO:0008237=IMP} PMA-inducible membrane protein ectodomain proteolysis, activation of MAPKK activity, cell adhesion, cell-cell adhesion mediated by integrin, cell-matrix adhesion, cellular response to lipopolysaccharide, collagen catabolic process, extracellular matrix disassembly, extracellular matrix organization, integrin-mediated signaling pathway, keratinocyte differentiation, membrane protein ectodomain proteolysis, monocyte activation, positive regulation of keratinocyte migration, positive regulation of macrophage fusion, positive regulation of membrane protein ectodomain proteolysis, proteolysis, response to calcium ion, response to glucocorticoid stimulus, response to hydrogen peroxide, response to manganese ion, response to tumor necrosis factor, transforming growth factor beta receptor signaling pathway cell surface, cytoplasm, extracellular space, integral to membrane, intrinsic to external side of plasma membrane SH3 domain binding, collagen binding, integrin binding, laminin binding, metalloendopeptidase activity, metallopeptidase activity, protein binding, protein kinase C binding, zinc ion binding Human ADAMDEC1 UniProtKB UniProtKB {GO:0006955=PMID:12037602, GO:0007162=PMID:9271581, GO:0006508=GO_REF:0000037, GO:0008270=PMID:12037602, GO:0005576=GO_REF:0000039, GO:0005575=GO_REF:0000015, GO:0004222=PMID:12037602} O15204 ADAM DEC1 protein 20111004 {GO:0006955=NAS, GO:0007162=NAS, GO:0006508=IEA, GO:0008270=NAS, GO:0005576=IEA, GO:0005575=ND, GO:0004222=NAS} immune response, negative regulation of cell adhesion, proteolysis cellular_component, extracellular region metalloendopeptidase activity, zinc ion binding Human ADAMTS1 PINC UniProtKB {GO:0060347=GO_REF:0000019, GO:0008285=PMID:10438512, GO:0007229=PMID:8995297, GO:0001822=GO_REF:0000019, GO:0006508=GO_REF:0000037, GO:0008270=GO_REF:0000002, GO:0001542=GO_REF:0000019, GO:0031410=GO_REF:0000019, GO:0004222=GO_REF:0000019, GO:0008201=GO_REF:0000019, GO:0008237=PMID:10438512, GO:0005604=GO_REF:0000019} Q9UHI8 A disintegrin and metalloproteinase with thrombospondin motifs 1 protein 20030904 {GO:0060347=IEA, GO:0008285=TAS, GO:0007229=TAS, GO:0001822=IEA, GO:0006508=IEA, GO:0008270=IEA, GO:0001542=IEA, GO:0031410=IEA, GO:0004222=IEA, GO:0008201=IEA, GO:0008237=TAS, GO:0005604=IEA} heart trabecula formation, integrin-mediated signaling pathway, kidney development, negative regulation of cell proliferation, ovulation from ovarian follicle, proteolysis basement membrane, cytoplasmic vesicle heparin binding, metalloendopeptidase activity, metallopeptidase activity, zinc ion binding Human ADAMTS10 UniProtKB UniProtKB {GO:0005515=PMID:21402694, GO:0031012=PMID:21402694, GO:0003674=GO_REF:0000015, GO:0008150=GO_REF:0000015, GO:0005578=GO_REF:0000002, GO:0006508=GO_REF:0000037, GO:0001527=PMID:21402694, GO:0008270=GO_REF:0000002, GO:0005575=GO_REF:0000015, GO:0004222=GO_REF:0000002} Q9H324 A disintegrin and metalloproteinase with thrombospondin motifs 10 protein 20120620 {GO:0005515=IPI, GO:0031012=IDA, GO:0003674=ND, GO:0008150=ND, GO:0005578=IEA, GO:0006508=IEA, GO:0001527=IDA, GO:0008270=IEA, GO:0005575=ND, GO:0004222=IEA} biological_process, proteolysis cellular_component, extracellular matrix, microfibril, proteinaceous extracellular matrix metalloendopeptidase activity, molecular_function, protein binding, zinc ion binding Human UniProtKB:P35555 ADAMTS13 IntAct UniProtKB {GO:0005515=PMID:16221672, GO:0009986=PMID:11557746, GO:0005509=PMID:11557746, GO:0005578=PMID:11557746, GO:0030168=PMID:11557746, GO:0005615=GO_REF:0000019, GO:0009100=PMID:11557746, GO:0005178=PMID:11557746, GO:0007160=PMID:11557746, GO:0007229=PMID:11557746, GO:0016485=PMID:11557746, GO:0006508=PMID:11535495, GO:0008270=PMID:11557746, GO:0004222=GO_REF:0000002, GO:0043171=PMID:11535495, GO:0008237=PMID:11557746} Q76LX8 A disintegrin and metalloproteinase with thrombospondin motifs 13 protein 20130415 {GO:0005515=IPI, GO:0009986=NAS, GO:0005509=TAS, GO:0005578=TAS, GO:0030168=NAS, GO:0005615=IEA, GO:0009100=NAS, GO:0005178=TAS, GO:0007160=NAS, GO:0007229=NAS, GO:0016485=TAS, GO:0006508=IDA, GO:0008270=TAS, GO:0004222=IEA, GO:0043171=IDA, GO:0008237=TAS} cell-matrix adhesion, glycoprotein metabolic process, integrin-mediated signaling pathway, peptide catabolic process, platelet activation, protein processing, proteolysis cell surface, extracellular space, proteinaceous extracellular matrix calcium ion binding, integrin binding, metalloendopeptidase activity, metallopeptidase activity, protein binding, zinc ion binding Human UniProtKB:P04275 ADAMTS17 UniProtKB UniProtKB {GO:0006508=GO_REF:0000037, GO:0005578=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0004222=GO_REF:0000002} Q8TE56 A disintegrin and metalloproteinase with thrombospondin motifs 17 protein 20130413 {GO:0006508=IEA, GO:0005578=IEA, GO:0008270=IEA, GO:0004222=IEA} proteolysis proteinaceous extracellular matrix metalloendopeptidase activity, zinc ion binding Human UniProtKB-SubCell:SL-0111 ADAMTS2 Reactome UniProtKB {GO:0030324=GO_REF:0000019, GO:0005578=GO_REF:0000039, GO:0005576=Reactome:REACT_121172, GO:0007283=GO_REF:0000019, GO:0016485=GO_REF:0000019, GO:0030198=Reactome:REACT_118779, GO:0030199=GO_REF:0000019, GO:0030574=GO_REF:0000037, GO:0006508=GO_REF:0000037, GO:0008270=GO_REF:0000002, GO:0043588=GO_REF:0000019, GO:0004222=GO_REF:0000002, GO:0008237=PMID:10417273} O95450 A disintegrin and metalloproteinase with thrombospondin motifs 2 protein 20130301 {GO:0030324=IEA, GO:0005578=IEA, GO:0005576=TAS, GO:0007283=IEA, GO:0016485=IEA, GO:0030198=TAS, GO:0030199=IEA, GO:0030574=IEA, GO:0006508=IEA, GO:0008270=IEA, GO:0043588=IEA, GO:0004222=IEA, GO:0008237=TAS} collagen catabolic process, collagen fibril organization, extracellular matrix organization, lung development, protein processing, proteolysis, skin development, spermatogenesis extracellular region, proteinaceous extracellular matrix metalloendopeptidase activity, metallopeptidase activity, zinc ion binding Human ADAMTS4 InterPro UniProtKB {GO:0005515=PMID:18718938, GO:0001501=PMID:10356395, GO:0005578=GO_REF:0000039, GO:0006508=GO_REF:0000002, GO:0008233=PMID:10751421, GO:0008270=GO_REF:0000002, GO:0002020=PMID:14744861, GO:0004222=GO_REF:0000002, GO:0005615=PMID:14744861, GO:0008237=PMID:10356395} Q5VTW1 A disintegrin and metalloproteinase with thrombospondin motifs 4 protein 20130413 {GO:0005515=IPI, GO:0001501=TAS, GO:0005578=IEA, GO:0006508=IEA, GO:0008233=TAS, GO:0008270=IEA, GO:0002020=IPI, GO:0004222=IEA, GO:0005615=IDA, GO:0008237=TAS} proteolysis, skeletal system development extracellular space, proteinaceous extracellular matrix metalloendopeptidase activity, metallopeptidase activity, peptidase activity, protease binding, protein binding, zinc ion binding Human InterPro:IPR002870 ADAMTS5 HPA UniProtKB {GO:0005515=PMID:22406378, GO:0005737=GO_REF:0000052, GO:0005178=PMID:10438522, GO:0005730=GO_REF:0000052, GO:0005578=GO_REF:0000039, GO:0006508=GO_REF:0000037, GO:0005634=GO_REF:0000052, GO:0008270=GO_REF:0000002, GO:0004222=GO_REF:0000002, GO:0008237=PMID:10438522} Q9UNA0 A disintegrin and metalloproteinase with thrombospondin motifs 5 protein 20120912 {GO:0005515=IPI, GO:0005737=IDA, GO:0005178=TAS, GO:0005730=IDA, GO:0005578=IEA, GO:0006508=IEA, GO:0005634=IDA, GO:0008270=IEA, GO:0004222=IEA, GO:0008237=TAS} proteolysis cytoplasm, nucleolus, nucleus, proteinaceous extracellular matrix integrin binding, metalloendopeptidase activity, metallopeptidase activity, protein binding, zinc ion binding Human ADAMTSL2 BHF-UCL UniProtKB {GO:0005515=PMID:18677313, GO:0005578=GO_REF:0000002, GO:0008270=GO_REF:0000002, GO:0004222=GO_REF:0000002, GO:0030512=PMID:18677313} Q86TH1 ADAMTS-like protein 2 protein 20101031 {GO:0005515=IPI, GO:0005578=IEA, GO:0008270=IEA, GO:0004222=IEA, GO:0030512=IMP} negative regulation of transforming growth factor beta receptor signaling pathway proteinaceous extracellular matrix metalloendopeptidase activity, protein binding, zinc ion binding Human ADAMTSL4 IntAct UniProtKB {GO:0005515=PMID:19060904, GO:0031012=GO_REF:0000002, GO:0043065=PMID:16364318, GO:0030198=GO_REF:0000019, GO:0006915=GO_REF:0000037, GO:0005575=GO_REF:0000015, GO:0002020=PMID:16364318, GO:0005614=GO_REF:0000019, GO:0004222=GO_REF:0000002} Q6UY14 ADAMTS-like protein 4 protein 20130415 {GO:0005515=IPI, GO:0031012=IEA, GO:0043065=IDA, GO:0030198=IEA, GO:0006915=IEA, GO:0005575=ND, GO:0002020=IPI, GO:0005614=IEA, GO:0004222=IEA} apoptotic process, extracellular matrix organization, positive regulation of apoptotic process cellular_component, extracellular matrix, interstitial matrix metalloendopeptidase activity, protease binding, protein binding Human UniProtKB:O75716 ADAMTSL5 InterPro UniProtKB {GO:0031012=GO_REF:0000002, GO:0005578=GO_REF:0000002, GO:0005576=GO_REF:0000038, GO:0008270=GO_REF:0000002, GO:0004222=GO_REF:0000002} Q6ZMM2 ADAMTS-like protein 5 protein 20130413 {GO:0031012=IEA, GO:0005578=IEA, GO:0005576=IEA, GO:0008270=IEA, GO:0004222=IEA} extracellular matrix, extracellular region, proteinaceous extracellular matrix metalloendopeptidase activity, zinc ion binding Human InterPro:IPR013273 ADAP1 HPA UniProtKB {GO:0005515=PMID:12893243, GO:0008060=PMID:10448098, GO:0043533=PMID:12018390, GO:0005737=GO_REF:0000052, GO:0005543=GO_REF:0000002, GO:0005886=PMID:10448098, GO:0032312=GO_REF:0000002, GO:0005634=PMID:10448098, GO:0008270=GO_REF:0000002, GO:0007166=PMID:10333475, GO:0043087=PMID:10333475} O75689 Arf-GAP with dual PH domain-containing protein 1 protein 20080205 {GO:0005515=IPI, GO:0008060=IDA, GO:0043533=TAS, GO:0005737=IDA, GO:0005543=IEA, GO:0005886=IDA, GO:0032312=IEA, GO:0005634=IDA, GO:0008270=IEA, GO:0007166=TAS, GO:0043087=IMP} cell surface receptor signaling pathway, regulation of ARF GTPase activity, regulation of GTPase activity cytoplasm, nucleus, plasma membrane ARF GTPase activator activity, inositol 1,3,4,5 tetrakisphosphate binding, phospholipid binding, protein binding, zinc ion binding Human ADAP2 GOC UniProtKB {GO:0005515=PMID:20098747, GO:0005886=PMID:14690521, GO:0043325=PMID:12018390, GO:0005547=PMID:14690521, GO:0005546=PMID:12018390, GO:0005740=PMID:12018390, GO:0043547=GO_REF:0000029, GO:0007507=PMID:16138909, GO:0008060=GO_REF:0000002, GO:0005737=PMID:14690521, GO:0043533=PMID:14690521, GO:0005543=GO_REF:0000002, GO:0032312=GO_REF:0000002, GO:0008270=GO_REF:0000002, GO:0030674=PMID:14690521, GO:0005096=GO_REF:0000029} Q9NPF8 Arf-GAP with dual PH domain-containing protein 2 protein 20130413 {GO:0005515=IPI, GO:0005886=IDA, GO:0043325=ISS, GO:0005547=IDA, GO:0005546=ISS, GO:0005740=ISS, GO:0043547=NAS, GO:0007507=IEP, GO:0008060=IEA, GO:0005737=IDA, GO:0043533=IDA, GO:0005543=IEA, GO:0032312=IEA, GO:0008270=IEA, GO:0030674=NAS, GO:0005096=NAS} heart development, positive regulation of GTPase activity, regulation of ARF GTPase activity cytoplasm, mitochondrial envelope, plasma membrane ARF GTPase activator activity, GTPase activator activity, inositol 1,3,4,5 tetrakisphosphate binding, phosphatidylinositol-3,4,5-trisphosphate binding, phosphatidylinositol-3,4-bisphosphate binding, phosphatidylinositol-4,5-bisphosphate binding, phospholipid binding, protein binding, protein binding, bridging, zinc ion binding Human ADAR HPA UniProtKB {GO:0003725=GO_REF:0000002, GO:0005515=PMID:18362360, GO:0010467=Reactome:REACT_71, GO:0003726=PMID:9020165, GO:0035455=PMID:16475990, GO:0019221=Reactome:REACT_25229, GO:0005634=GO_REF:0000052, GO:0031047=GO_REF:0000037, GO:0006382=Reactome:REACT_18, GO:0046872=GO_REF:0000037, GO:0005737=PMID:7565688, GO:0051607=GO_REF:0000037, GO:0060337=Reactome:REACT_25162, GO:0044530=PMID:18362360, GO:0045070=PMID:19651874, GO:0006397=GO_REF:0000037, GO:0006396=GO_REF:0000002, GO:0043066=GO_REF:0000019, GO:0016556=Reactome:REACT_1757, GO:0016553=PMID:9020165, GO:0005730=GO_REF:0000039, GO:0009615=PMID:15858013, GO:0003677=GO_REF:0000037, GO:0044387=PMID:18362360, GO:0045087=PMID:16475990, GO:0005654=Reactome:REACT_25192} P55265 Double-stranded RNA-specific adenosine deaminase protein 20101115 {GO:0003725=IEA, GO:0005515=IPI, GO:0010467=TAS, GO:0003726=IDA, GO:0035455=IDA, GO:0019221=TAS, GO:0005634=IDA, GO:0031047=IEA, GO:0006382=TAS, GO:0046872=IEA, GO:0005737=TAS, GO:0051607=IEA, GO:0060337=TAS, GO:0044530=IDA, GO:0045070=IDA, GO:0006397=IEA, GO:0006396=IEA, GO:0043066=IEA, GO:0016556=TAS, GO:0016553=IDA, GO:0005730=IEA, GO:0009615=IMP, GO:0003677=IEA, GO:0044387=IMP, GO:0045087=TAS, GO:0005654=TAS} RNA processing, adenosine to inosine editing, base conversion or substitution editing, cytokine-mediated signaling pathway, defense response to virus, gene expression, gene silencing by RNA, innate immune response, mRNA modification, mRNA processing, negative regulation of apoptotic process, negative regulation of protein kinase activity by regulation of protein phosphorylation, positive regulation of viral genome replication, response to interferon-alpha, response to virus, type I interferon-mediated signaling pathway cytoplasm, nucleolus, nucleoplasm, nucleus, supraspliceosomal complex DNA binding, double-stranded RNA adenosine deaminase activity, double-stranded RNA binding, metal ion binding, protein binding Human ADARB1 BHF-UCL UniProtKB {GO:0003725=GO_REF:0000002, GO:0006397=GO_REF:0000037, GO:0010467=Reactome:REACT_71, GO:0006396=GO_REF:0000002, GO:0030336=PMID:18178553, GO:0008285=PMID:18178553, GO:0016556=Reactome:REACT_1757, GO:0005730=PMID:18178553, GO:0003729=PMID:9149227, GO:0006382=Reactome:REACT_18, GO:0046872=GO_REF:0000037, GO:0051607=GO_REF:0000037, GO:0004000=GO_REF:0000002, GO:0044387=PMID:21289159, GO:0045087=GO_REF:0000037, GO:0051726=PMID:18178553, GO:0005654=Reactome:REACT_990, GO:0045070=PMID:21289159} P78563 Double-stranded RNA-specific editase 1 protein 20090928 {GO:0003725=IEA, GO:0006397=IEA, GO:0010467=TAS, GO:0006396=IEA, GO:0030336=IDA, GO:0008285=IDA, GO:0016556=TAS, GO:0005730=IDA, GO:0003729=TAS, GO:0006382=TAS, GO:0046872=IEA, GO:0051607=IEA, GO:0004000=IEA, GO:0044387=IDA, GO:0045087=IEA, GO:0051726=IDA, GO:0005654=TAS, GO:0045070=IMP} RNA processing, adenosine to inosine editing, defense response to virus, gene expression, innate immune response, mRNA modification, mRNA processing, negative regulation of cell migration, negative regulation of cell proliferation, negative regulation of protein kinase activity by regulation of protein phosphorylation, positive regulation of viral genome replication, regulation of cell cycle nucleolus, nucleoplasm adenosine deaminase activity, double-stranded RNA binding, mRNA binding, metal ion binding Human ADARB2 HPA UniProtKB {GO:0005739=GO_REF:0000052, GO:0006397=GO_REF:0000037, GO:0003725=GO_REF:0000002, GO:0006396=GO_REF:0000002, GO:0005737=GO_REF:0000052, GO:0003727=PMID:10836796, GO:0004000=GO_REF:0000002, GO:0003723=GO_REF:0000002, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0046872=GO_REF:0000037} Q9NS39 Double-stranded RNA-specific editase B2 protein 20101115 {GO:0005739=IDA, GO:0006397=IEA, GO:0003725=IEA, GO:0006396=IEA, GO:0005737=IDA, GO:0003727=TAS, GO:0004000=IEA, GO:0003723=IEA, GO:0005730=IDA, GO:0005634=IDA, GO:0046872=IEA} RNA processing, mRNA processing cytoplasm, mitochondrion, nucleolus, nucleus RNA binding, adenosine deaminase activity, double-stranded RNA binding, metal ion binding, single-stranded RNA binding Human ADAT1 UniProtKB UniProtKB {GO:0006396=GO_REF:0000002, GO:0004000=GO_REF:0000002, GO:0003723=PMID:10430867, GO:0008251=PMID:10430867, GO:0008033=PMID:10430867, GO:0046872=GO_REF:0000037} Q9BUB4 tRNA-specific adenosine deaminase 1 protein 20080312 {GO:0006396=IEA, GO:0004000=IEA, GO:0003723=IMP, GO:0008251=IMP, GO:0008033=IMP, GO:0046872=IEA} RNA processing, tRNA processing RNA binding, adenosine deaminase activity, metal ion binding, tRNA-specific adenosine deaminase activity Human ADAT2 UniProtKB UniProtKB {GO:0016787=GO_REF:0000037, GO:0008270=GO_REF:0000002, GO:0008033=GO_REF:0000037} Q7Z6V5 tRNA-specific adenosine deaminase 2 protein 20130413 {GO:0016787=IEA, GO:0008270=IEA, GO:0008033=IEA} tRNA processing hydrolase activity, zinc ion binding Human UniProtKB-KW:KW-0378 ADAT3 UniProtKB UniProtKB {GO:0016787=GO_REF:0000002, GO:0008270=GO_REF:0000002, GO:0008033=GO_REF:0000037} Q96EY9 Probable inactive tRNA-specific adenosine deaminase-like protein 3 protein 20130413 {GO:0016787=IEA, GO:0008270=IEA, GO:0008033=IEA} tRNA processing hydrolase activity, zinc ion binding Human UniProtKB-KW:KW-0819 ADCK1 UniProtKB UniProtKB {GO:0005739=GO_REF:0000019, GO:0016301=GO_REF:0000038, GO:0004674=GO_REF:0000037, GO:0005576=GO_REF:0000039, GO:0005524=GO_REF:0000037} Q9UIE6 Uncharacterized aarF domain-containing protein kinase 1 protein 20130413 {GO:0005739=IEA, GO:0016301=IEA, GO:0004674=IEA, GO:0005576=IEA, GO:0005524=IEA} extracellular region, mitochondrion ATP binding, kinase activity, protein serine/threonine kinase activity Human UniProtKB-KW:KW-0418 ADCK2 ENSEMBL UniProtKB {GO:0005739=GO_REF:0000019, GO:0004672=GO_REF:0000002, GO:0004674=GO_REF:0000037, GO:0016021=GO_REF:0000037, GO:0005524=GO_REF:0000037} Q7Z695 Uncharacterized aarF domain-containing protein kinase 2 protein 20130413 {GO:0005739=IEA, GO:0004672=IEA, GO:0004674=IEA, GO:0016021=IEA, GO:0005524=IEA} integral to membrane, mitochondrion ATP binding, protein kinase activity, protein serine/threonine kinase activity Human Ensembl:ENSMUSP00000123563 ADCK3 UniProtKB UniProtKB {GO:0005739=GO_REF:0000039, GO:0008219=GO_REF:0000037, GO:0004674=GO_REF:0000037, GO:0005524=GO_REF:0000037, GO:0016772=GO_REF:0000002} Q8NI60 Chaperone activity of bc1 complex-like, mitochondrial protein 20130413 {GO:0005739=IEA, GO:0008219=IEA, GO:0004674=IEA, GO:0005524=IEA, GO:0016772=IEA} cell death mitochondrion ATP binding, protein serine/threonine kinase activity, transferase activity, transferring phosphorus-containing groups Human UniProtKB-SubCell:SL-0173 ADCK4 ENSEMBL UniProtKB {GO:0005739=GO_REF:0000019, GO:0004674=GO_REF:0000037, GO:0016021=GO_REF:0000037} Q96D53 Uncharacterized aarF domain-containing protein kinase 4 protein 20130413 {GO:0005739=IEA, GO:0004674=IEA, GO:0016021=IEA} integral to membrane, mitochondrion protein serine/threonine kinase activity Human Ensembl:ENSMUSP00000104015 ADCK5 ENSEMBL UniProtKB {GO:0005739=GO_REF:0000019, GO:0004674=GO_REF:0000037, GO:0016021=GO_REF:0000037} Q3MIX3 Uncharacterized aarF domain-containing protein kinase 5 protein 20130413 {GO:0005739=IEA, GO:0004674=IEA, GO:0016021=IEA} integral to membrane, mitochondrion protein serine/threonine kinase activity Human Ensembl:ENSMUSP00000125055 ADCY1 Reactome UniProtKB {GO:0005516=GO_REF:0000029, GO:0005886=Reactome:REACT_20564, GO:0007268=Reactome:REACT_13685, GO:0005634=GO_REF:0000019, GO:0044281=Reactome:REACT_111217, GO:0007409=GO_REF:0000019, GO:0007202=Reactome:REACT_12079, GO:0007193=Reactome:REACT_15333, GO:0046872=GO_REF:0000037, GO:0035556=GO_REF:0000002, GO:0000166=GO_REF:0000038, GO:0007173=Reactome:REACT_9417, GO:0071377=Reactome:REACT_1665, GO:0006171=GO_REF:0000029, GO:0006833=Reactome:REACT_24023, GO:0034199=Reactome:REACT_15530, GO:0048011=Reactome:REACT_11061, GO:0007616=GO_REF:0000019, GO:0016849=GO_REF:0000002, GO:0042493=GO_REF:0000019, GO:0008294=PMID:8314585, GO:0055085=Reactome:REACT_15518, GO:0005524=GO_REF:0000037, GO:0007165=Reactome:REACT_12478, GO:0010226=GO_REF:0000019, GO:0006112=Reactome:REACT_1505, GO:0008543=Reactome:REACT_9470, GO:0045087=Reactome:REACT_6802, GO:0007623=GO_REF:0000019, GO:0016021=GO_REF:0000029, GO:0007189=Reactome:REACT_15312, GO:0009190=GO_REF:0000002} Q08828 Adenylate cyclase type 1 protein 20130301 {GO:0005516=NAS, GO:0005886=TAS, GO:0007268=TAS, GO:0005634=IEA, GO:0044281=TAS, GO:0007409=IEA, GO:0007202=TAS, GO:0007193=TAS, GO:0046872=IEA, GO:0035556=IEA, GO:0000166=IEA, GO:0007173=TAS, GO:0071377=TAS, GO:0006171=NAS, GO:0006833=TAS, GO:0034199=TAS, GO:0048011=TAS, GO:0007616=IEA, GO:0016849=IEA, GO:0042493=IEA, GO:0008294=NAS, GO:0055085=TAS, GO:0005524=IEA, GO:0007165=TAS, GO:0010226=IEA, GO:0006112=TAS, GO:0008543=TAS, GO:0045087=TAS, GO:0007623=IEA, GO:0016021=NAS, GO:0007189=TAS, GO:0009190=IEA} activation of phospholipase C activity, activation of protein kinase A activity, adenylate cyclase-activating G-protein coupled receptor signaling pathway, adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway, axonogenesis, cAMP biosynthetic process, cellular response to glucagon stimulus, circadian rhythm, cyclic nucleotide biosynthetic process, energy reserve metabolic process, epidermal growth factor receptor signaling pathway, fibroblast growth factor receptor signaling pathway, innate immune response, intracellular signal transduction, long-term memory, neurotrophin TRK receptor signaling pathway, response to drug, response to lithium ion, signal transduction, small molecule metabolic process, synaptic transmission, transmembrane transport, water transport integral to membrane, nucleus, plasma membrane ATP binding, calcium- and calmodulin-responsive adenylate cyclase activity, calmodulin binding, metal ion binding, nucleotide binding, phosphorus-oxygen lyase activity Human ADCY10 PINC UniProtKB {GO:0030424=GO_REF:0000019, GO:0048471=GO_REF:0000039, GO:0000287=GO_REF:0000002, GO:0030145=GO_REF:0000019, GO:0043065=GO_REF:0000019, GO:0005886=GO_REF:0000039, GO:0045178=GO_REF:0000019, GO:0045177=GO_REF:0000019, GO:0007283=GO_REF:0000002, GO:0005524=GO_REF:0000037, GO:0030425=GO_REF:0000019, GO:0005829=PMID:9874775, GO:0030426=GO_REF:0000019, GO:0035556=GO_REF:0000002, GO:0005737=PMID:9874775, GO:0004016=PMID:9874775, GO:0043025=GO_REF:0000019, GO:0006171=PMID:9874775, GO:0051117=GO_REF:0000019, GO:0005856=GO_REF:0000039} Q96PN6 Adenylate cyclase type 10 protein 20030904 {GO:0030424=IEA, GO:0048471=IEA, GO:0000287=IEA, GO:0030145=IEA, GO:0043065=IEA, GO:0005886=IEA, GO:0045178=IEA, GO:0045177=IEA, GO:0007283=IEA, GO:0005524=IEA, GO:0030425=IEA, GO:0005829=NAS, GO:0030426=IEA, GO:0035556=IEA, GO:0005737=TAS, GO:0004016=NAS, GO:0043025=IEA, GO:0006171=NAS, GO:0051117=IEA, GO:0005856=IEA} cAMP biosynthetic process, intracellular signal transduction, positive regulation of apoptotic process, spermatogenesis apical part of cell, axon, basal part of cell, cytoplasm, cytoskeleton, cytosol, dendrite, growth cone, neuronal cell body, perinuclear region of cytoplasm, plasma membrane ATP binding, ATPase binding, adenylate cyclase activity, magnesium ion binding, manganese ion binding Human ADCY2 BHF-UCL UniProtKB {GO:0005886=Reactome:REACT_19147, GO:0007268=Reactome:REACT_13685, GO:0044281=Reactome:REACT_111217, GO:0007202=Reactome:REACT_12079, GO:0007193=Reactome:REACT_15333, GO:0030425=GO_REF:0000024, GO:0046872=GO_REF:0000037, GO:0005622=GO_REF:0000024, GO:0035556=GO_REF:0000002, GO:0005737=PMID:11549699, GO:0000166=GO_REF:0000038, GO:0007173=Reactome:REACT_9417, GO:0071377=Reactome:REACT_1665, GO:0006171=GO_REF:0000024, GO:0006833=Reactome:REACT_24023, GO:0034199=Reactome:REACT_15530, GO:0048011=Reactome:REACT_11061, GO:0046982=GO_REF:0000024, GO:0008179=GO_REF:0000024, GO:0008294=GO_REF:0000019, GO:0031683=GO_REF:0000019, GO:0055085=Reactome:REACT_15518, GO:0005524=GO_REF:0000037, GO:0043234=GO_REF:0000019, GO:0007165=Reactome:REACT_12478, GO:0004016=GO_REF:0000024, GO:0006112=Reactome:REACT_1505, GO:0016020=GO_REF:0000024, GO:0008543=Reactome:REACT_9470, GO:0045087=Reactome:REACT_6802, GO:0045121=GO_REF:0000024, GO:0007188=GO_REF:0000024, GO:0016021=GO_REF:0000029, GO:0007189=Reactome:REACT_15312} Q08462 Adenylate cyclase type 2 protein 20120516 {GO:0005886=TAS, GO:0007268=TAS, GO:0044281=TAS, GO:0007202=TAS, GO:0007193=TAS, GO:0030425=ISS, GO:0046872=IEA, GO:0005622=ISS, GO:0035556=IEA, GO:0005737=IDA, GO:0000166=IEA, GO:0007173=TAS, GO:0071377=TAS, GO:0006171=ISS, GO:0006833=TAS, GO:0034199=TAS, GO:0048011=TAS, GO:0046982=ISS, GO:0008179=ISS, GO:0008294=IEA, GO:0031683=IEA, GO:0055085=TAS, GO:0005524=IEA, GO:0043234=IEA, GO:0007165=TAS, GO:0004016=ISS, GO:0006112=TAS, GO:0016020=ISS, GO:0008543=TAS, GO:0045087=TAS, GO:0045121=ISS, GO:0007188=ISS, GO:0016021=NAS, GO:0007189=TAS} activation of phospholipase C activity, activation of protein kinase A activity, adenylate cyclase-activating G-protein coupled receptor signaling pathway, adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway, adenylate cyclase-modulating G-protein coupled receptor signaling pathway, cAMP biosynthetic process, cellular response to glucagon stimulus, energy reserve metabolic process, epidermal growth factor receptor signaling pathway, fibroblast growth factor receptor signaling pathway, innate immune response, intracellular signal transduction, neurotrophin TRK receptor signaling pathway, signal transduction, small molecule metabolic process, synaptic transmission, transmembrane transport, water transport cytoplasm, dendrite, integral to membrane, intracellular, membrane, membrane raft, plasma membrane, protein complex ATP binding, G-protein beta/gamma-subunit complex binding, adenylate cyclase activity, adenylate cyclase binding, calcium- and calmodulin-responsive adenylate cyclase activity, metal ion binding, nucleotide binding, protein heterodimerization activity Human UniProtKB:G0TC75 ADCY3 Reactome UniProtKB {GO:0007608=GO_REF:0000037, GO:0005516=GO_REF:0000037, GO:0005886=Reactome:REACT_20564, GO:0007268=Reactome:REACT_13685, GO:0007202=Reactome:REACT_12079, GO:0044281=Reactome:REACT_111217, GO:0007193=Reactome:REACT_15333, GO:0046872=GO_REF:0000037, GO:0035556=GO_REF:0000002, GO:0005737=PMID:11549699, GO:0000166=GO_REF:0000038, GO:0007173=Reactome:REACT_9417, GO:0071377=Reactome:REACT_1665, GO:0006833=Reactome:REACT_24023, GO:0034199=Reactome:REACT_15530, GO:0048011=Reactome:REACT_11061, GO:0016849=GO_REF:0000002, GO:0055085=Reactome:REACT_15518, GO:0005524=GO_REF:0000037, GO:0007165=Reactome:REACT_12478, GO:0006112=Reactome:REACT_1505, GO:0004016=GO_REF:0000003, GO:0005887=PMID:9920776, GO:0008543=Reactome:REACT_9470, GO:0045087=Reactome:REACT_6802, GO:0007189=Reactome:REACT_15312, GO:0009190=GO_REF:0000002} O60266 Adenylate cyclase type 3 protein 20130301 {GO:0007608=IEA, GO:0005516=IEA, GO:0005886=TAS, GO:0007268=TAS, GO:0007202=TAS, GO:0044281=TAS, GO:0007193=TAS, GO:0046872=IEA, GO:0035556=IEA, GO:0005737=IDA, GO:0000166=IEA, GO:0007173=TAS, GO:0071377=TAS, GO:0006833=TAS, GO:0034199=TAS, GO:0048011=TAS, GO:0016849=IEA, GO:0055085=TAS, GO:0005524=IEA, GO:0007165=TAS, GO:0006112=TAS, GO:0004016=IEA, GO:0005887=TAS, GO:0008543=TAS, GO:0045087=TAS, GO:0007189=TAS, GO:0009190=IEA} activation of phospholipase C activity, activation of protein kinase A activity, adenylate cyclase-activating G-protein coupled receptor signaling pathway, adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway, cellular response to glucagon stimulus, cyclic nucleotide biosynthetic process, energy reserve metabolic process, epidermal growth factor receptor signaling pathway, fibroblast growth factor receptor signaling pathway, innate immune response, intracellular signal transduction, neurotrophin TRK receptor signaling pathway, sensory perception of smell, signal transduction, small molecule metabolic process, synaptic transmission, transmembrane transport, water transport cytoplasm, integral to plasma membrane, plasma membrane ATP binding, adenylate cyclase activity, calmodulin binding, metal ion binding, nucleotide binding, phosphorus-oxygen lyase activity Human ADCY4 BHF-UCL UniProtKB {GO:0005515=PMID:17081159, GO:0005886=Reactome:REACT_19147, GO:0007268=Reactome:REACT_13685, GO:0007202=Reactome:REACT_12079, GO:0044281=Reactome:REACT_111217, GO:0007193=Reactome:REACT_15333, GO:0046872=GO_REF:0000037, GO:0030425=GO_REF:0000019, GO:0005622=GO_REF:0000019, GO:0035556=GO_REF:0000002, GO:0005737=PMID:11549699, GO:0000166=GO_REF:0000038, GO:0007173=Reactome:REACT_9417, GO:0071377=Reactome:REACT_1665, GO:0006171=GO_REF:0000024, GO:0006833=Reactome:REACT_24023, GO:0034199=Reactome:REACT_15530, GO:0048011=Reactome:REACT_11061, GO:0016849=GO_REF:0000002, GO:0055085=Reactome:REACT_15518, GO:0005524=GO_REF:0000037, GO:0007165=Reactome:REACT_12478, GO:0004016=GO_REF:0000024, GO:0006112=Reactome:REACT_1505, GO:0016020=GO_REF:0000024, GO:0008543=Reactome:REACT_9470, GO:0045087=Reactome:REACT_6802, GO:0007188=GO_REF:0000024, GO:0016021=GO_REF:0000037, GO:0007189=Reactome:REACT_15312, GO:0009190=GO_REF:0000002} Q8NFM4 Adenylate cyclase type 4 protein 20120516 {GO:0005515=IPI, GO:0005886=TAS, GO:0007268=TAS, GO:0007202=TAS, GO:0044281=TAS, GO:0007193=TAS, GO:0046872=IEA, GO:0030425=IEA, GO:0005622=IEA, GO:0035556=IEA, GO:0005737=IDA, GO:0000166=IEA, GO:0007173=TAS, GO:0071377=TAS, GO:0006171=ISS, GO:0006833=TAS, GO:0034199=TAS, GO:0048011=TAS, GO:0016849=IEA, GO:0055085=TAS, GO:0005524=IEA, GO:0007165=TAS, GO:0004016=ISS, GO:0006112=TAS, GO:0016020=ISS, GO:0008543=TAS, GO:0045087=TAS, GO:0007188=ISS, GO:0016021=IEA, GO:0007189=TAS, GO:0009190=IEA} activation of phospholipase C activity, activation of protein kinase A activity, adenylate cyclase-activating G-protein coupled receptor signaling pathway, adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway, adenylate cyclase-modulating G-protein coupled receptor signaling pathway, cAMP biosynthetic process, cellular response to glucagon stimulus, cyclic nucleotide biosynthetic process, energy reserve metabolic process, epidermal growth factor receptor signaling pathway, fibroblast growth factor receptor signaling pathway, innate immune response, intracellular signal transduction, neurotrophin TRK receptor signaling pathway, signal transduction, small molecule metabolic process, synaptic transmission, transmembrane transport, water transport cytoplasm, dendrite, integral to membrane, intracellular, membrane, plasma membrane ATP binding, adenylate cyclase activity, metal ion binding, nucleotide binding, phosphorus-oxygen lyase activity, protein binding Human UniProtKB:P26770 ADCY5 BHF-UCL UniProtKB {GO:0005886=GO_REF:0000024, GO:0007268=Reactome:REACT_13685, GO:0044281=Reactome:REACT_111217, GO:0007195=GO_REF:0000019, GO:0007202=Reactome:REACT_12079, GO:0007193=Reactome:REACT_15333, GO:0046872=GO_REF:0000037, GO:0007191=GO_REF:0000019, GO:0035556=GO_REF:0000002, GO:0000166=GO_REF:0000038, GO:0007173=Reactome:REACT_9417, GO:0071377=Reactome:REACT_1665, GO:0050885=GO_REF:0000019, GO:0007626=GO_REF:0000019, GO:0006833=Reactome:REACT_24023, GO:0034199=Reactome:REACT_15530, GO:0048011=Reactome:REACT_11061, GO:0046982=GO_REF:0000024, GO:0008179=GO_REF:0000024, GO:0072372=GO_REF:0000024, GO:0055085=Reactome:REACT_15518, GO:0005524=GO_REF:0000037, GO:0007165=Reactome:REACT_12478, GO:0004016=GO_REF:0000003, GO:0006112=Reactome:REACT_1505, GO:0001973=GO_REF:0000019, GO:0008543=Reactome:REACT_9470, GO:0045087=Reactome:REACT_6802, GO:0016021=GO_REF:0000037, GO:0007189=Reactome:REACT_15312} O95622 Adenylate cyclase type 5 protein 20120323 {GO:0005886=ISS, GO:0007268=TAS, GO:0044281=TAS, GO:0007195=IEA, GO:0007202=TAS, GO:0007193=TAS, GO:0046872=IEA, GO:0007191=IEA, GO:0035556=IEA, GO:0000166=IEA, GO:0007173=TAS, GO:0071377=TAS, GO:0050885=IEA, GO:0007626=IEA, GO:0006833=TAS, GO:0034199=TAS, GO:0048011=TAS, GO:0046982=ISS, GO:0008179=ISS, GO:0072372=ISS, GO:0055085=TAS, GO:0005524=IEA, GO:0007165=TAS, GO:0004016=IEA, GO:0006112=TAS, GO:0001973=IEA, GO:0008543=TAS, GO:0045087=TAS, GO:0016021=IEA, GO:0007189=TAS} activation of phospholipase C activity, activation of protein kinase A activity, adenosine receptor signaling pathway, adenylate cyclase-activating G-protein coupled receptor signaling pathway, adenylate cyclase-activating dopamine receptor signaling pathway, adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway, adenylate cyclase-inhibiting dopamine receptor signaling pathway, cellular response to glucagon stimulus, energy reserve metabolic process, epidermal growth factor receptor signaling pathway, fibroblast growth factor receptor signaling pathway, innate immune response, intracellular signal transduction, locomotory behavior, neuromuscular process controlling balance, neurotrophin TRK receptor signaling pathway, signal transduction, small molecule metabolic process, synaptic transmission, transmembrane transport, water transport integral to membrane, plasma membrane, primary cilium ATP binding, adenylate cyclase activity, adenylate cyclase binding, metal ion binding, nucleotide binding, protein heterodimerization activity Human UniProtKB:P84309 ADCY6 BHF-UCL UniProtKB {GO:0005515=PMID:17081159, GO:0005886=Reactome:REACT_19147, GO:0007268=Reactome:REACT_13685, GO:0007202=Reactome:REACT_12079, GO:0044281=Reactome:REACT_111217, GO:0071380=PMID:18403039, GO:0007193=Reactome:REACT_15333, GO:0046872=GO_REF:0000037, GO:0035556=GO_REF:0000002, GO:0007173=Reactome:REACT_9417, GO:0071377=Reactome:REACT_1665, GO:0006171=PMID:18403039, GO:0006833=Reactome:REACT_24023, GO:0034199=Reactome:REACT_15530, GO:0048011=Reactome:REACT_11061, GO:0019901=GO_REF:0000024, GO:0007212=PMID:18403039, GO:0005524=GO_REF:0000037, GO:0055085=Reactome:REACT_15518, GO:0007165=Reactome:REACT_12478, GO:0005929=GO_REF:0000039, GO:0004016=PMID:18403039, GO:0006112=Reactome:REACT_1505, GO:0016020=GO_REF:0000024, GO:0008543=Reactome:REACT_9470, GO:0071870=PMID:18403039, GO:0045087=Reactome:REACT_6802, GO:0016021=GO_REF:0000037, GO:0007189=Reactome:REACT_15312} O43306 Adenylate cyclase type 6 protein 20120329 {GO:0005515=IPI, GO:0005886=TAS, GO:0007268=TAS, GO:0007202=TAS, GO:0044281=TAS, GO:0071380=IDA, GO:0007193=TAS, GO:0046872=IEA, GO:0035556=IEA, GO:0007173=TAS, GO:0071377=TAS, GO:0006171=IDA, GO:0006833=TAS, GO:0034199=TAS, GO:0048011=TAS, GO:0019901=ISS, GO:0007212=IDA, GO:0005524=IEA, GO:0055085=TAS, GO:0007165=TAS, GO:0005929=IEA, GO:0004016=IDA, GO:0006112=TAS, GO:0016020=ISS, GO:0008543=TAS, GO:0071870=IDA, GO:0045087=TAS, GO:0016021=IEA, GO:0007189=TAS} activation of phospholipase C activity, activation of protein kinase A activity, adenylate cyclase-activating G-protein coupled receptor signaling pathway, adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway, cAMP biosynthetic process, cellular response to catecholamine stimulus, cellular response to glucagon stimulus, cellular response to prostaglandin E stimulus, dopamine receptor signaling pathway, energy reserve metabolic process, epidermal growth factor receptor signaling pathway, fibroblast growth factor receptor signaling pathway, innate immune response, intracellular signal transduction, neurotrophin TRK receptor signaling pathway, signal transduction, small molecule metabolic process, synaptic transmission, transmembrane transport, water transport cilium, integral to membrane, membrane, plasma membrane ATP binding, adenylate cyclase activity, metal ion binding, protein binding, protein kinase binding Human ADCY7 Reactome UniProtKB {GO:0005886=Reactome:REACT_19147, GO:0030819=PMID:11113152, GO:0007268=Reactome:REACT_13685, GO:0007202=Reactome:REACT_12079, GO:0044281=Reactome:REACT_111217, GO:0007193=Reactome:REACT_15333, GO:0046872=GO_REF:0000037, GO:0035556=GO_REF:0000002, GO:0007173=Reactome:REACT_9417, GO:0071377=Reactome:REACT_1665, GO:0006833=Reactome:REACT_24023, GO:0034199=Reactome:REACT_15530, GO:0048011=Reactome:REACT_11061, GO:0016849=GO_REF:0000002, GO:0005524=GO_REF:0000037, GO:0055085=Reactome:REACT_15518, GO:0007165=Reactome:REACT_12478, GO:0071361=PMID:17760784, GO:0006112=Reactome:REACT_1505, GO:0004016=PMID:11113152, GO:0008543=Reactome:REACT_9470, GO:0045087=Reactome:REACT_6802, GO:0007189=Reactome:REACT_15312, GO:0016021=PMID:11113152, GO:0009190=GO_REF:0000002} P51828 Adenylate cyclase type 7 protein 20130301 {GO:0005886=TAS, GO:0030819=IDA, GO:0007268=TAS, GO:0007202=TAS, GO:0044281=TAS, GO:0007193=TAS, GO:0046872=IEA, GO:0035556=IEA, GO:0007173=TAS, GO:0071377=TAS, GO:0006833=TAS, GO:0034199=TAS, GO:0048011=TAS, GO:0016849=IEA, GO:0005524=IEA, GO:0055085=TAS, GO:0007165=TAS, GO:0071361=IDA, GO:0006112=TAS, GO:0004016=IDA, GO:0008543=TAS, GO:0045087=TAS, GO:0007189=TAS, GO:0016021=IDA, GO:0009190=IEA} activation of phospholipase C activity, activation of protein kinase A activity, adenylate cyclase-activating G-protein coupled receptor signaling pathway, adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway, cellular response to ethanol, cellular response to glucagon stimulus, cyclic nucleotide biosynthetic process, energy reserve metabolic process, epidermal growth factor receptor signaling pathway, fibroblast growth factor receptor signaling pathway, innate immune response, intracellular signal transduction, neurotrophin TRK receptor signaling pathway, positive regulation of cAMP biosynthetic process, signal transduction, small molecule metabolic process, synaptic transmission, transmembrane transport, water transport integral to membrane, plasma membrane ATP binding, adenylate cyclase activity, metal ion binding, phosphorus-oxygen lyase activity Human ADCY8 Reactome UniProtKB {GO:0005886=Reactome:REACT_20564, GO:0007268=Reactome:REACT_13685, GO:0007202=Reactome:REACT_12079, GO:0044281=Reactome:REACT_111217, GO:0007193=Reactome:REACT_15333, GO:0046872=GO_REF:0000037, GO:0035556=GO_REF:0000002, GO:0007173=Reactome:REACT_9417, GO:0000166=GO_REF:0000038, GO:0071377=Reactome:REACT_1665, GO:0007611=PMID:8076676, GO:0006833=Reactome:REACT_24023, GO:0034199=Reactome:REACT_15530, GO:0048011=Reactome:REACT_11061, GO:0007616=GO_REF:0000019, GO:0008294=PMID:8163524, GO:0005524=GO_REF:0000037, GO:0055085=Reactome:REACT_15518, GO:0007165=Reactome:REACT_12478, GO:0006112=Reactome:REACT_1505, GO:0004016=PMID:8076676, GO:0016020=PMID:8163524, GO:0008543=Reactome:REACT_9470, GO:0045087=Reactome:REACT_6802, GO:0016021=GO_REF:0000037, GO:0007189=Reactome:REACT_15312} P40145 Adenylate cyclase type 8 protein 20130301 {GO:0005886=TAS, GO:0007268=TAS, GO:0007202=TAS, GO:0044281=TAS, GO:0007193=TAS, GO:0046872=IEA, GO:0035556=IEA, GO:0007173=TAS, GO:0000166=IEA, GO:0071377=TAS, GO:0007611=TAS, GO:0006833=TAS, GO:0034199=TAS, GO:0048011=TAS, GO:0007616=IEA, GO:0008294=TAS, GO:0005524=IEA, GO:0055085=TAS, GO:0007165=TAS, GO:0006112=TAS, GO:0004016=TAS, GO:0016020=TAS, GO:0008543=TAS, GO:0045087=TAS, GO:0016021=IEA, GO:0007189=TAS} activation of phospholipase C activity, activation of protein kinase A activity, adenylate cyclase-activating G-protein coupled receptor signaling pathway, adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway, cellular response to glucagon stimulus, energy reserve metabolic process, epidermal growth factor receptor signaling pathway, fibroblast growth factor receptor signaling pathway, innate immune response, intracellular signal transduction, learning or memory, long-term memory, neurotrophin TRK receptor signaling pathway, signal transduction, small molecule metabolic process, synaptic transmission, transmembrane transport, water transport integral to membrane, membrane, plasma membrane ATP binding, adenylate cyclase activity, calcium- and calmodulin-responsive adenylate cyclase activity, metal ion binding, nucleotide binding Human ADCY9 Reactome UniProtKB {GO:0048011=Reactome:REACT_11061, GO:0016849=GO_REF:0000002, GO:0005886=Reactome:REACT_19147, GO:0007268=Reactome:REACT_13685, GO:0044281=Reactome:REACT_111217, GO:0007202=Reactome:REACT_12079, GO:0055085=Reactome:REACT_15518, GO:0007193=Reactome:REACT_15333, GO:0005524=GO_REF:0000037, GO:0046872=GO_REF:0000037, GO:0035556=GO_REF:0000002, GO:0007165=Reactome:REACT_12478, GO:0004016=GO_REF:0000003, GO:0006112=Reactome:REACT_1505, GO:0007173=Reactome:REACT_9417, GO:0071377=Reactome:REACT_1665, GO:0008543=Reactome:REACT_9470, GO:0005887=PMID:9628827, GO:0045087=Reactome:REACT_6802, GO:0006833=Reactome:REACT_24023, GO:0007189=Reactome:REACT_15312, GO:0034199=Reactome:REACT_15530, GO:0009190=GO_REF:0000002} O60503 Adenylate cyclase type 9 protein 20130301 {GO:0048011=TAS, GO:0016849=IEA, GO:0005886=TAS, GO:0007268=TAS, GO:0044281=TAS, GO:0007202=TAS, GO:0055085=TAS, GO:0007193=TAS, GO:0005524=IEA, GO:0046872=IEA, GO:0035556=IEA, GO:0007165=TAS, GO:0004016=IEA, GO:0006112=TAS, GO:0007173=TAS, GO:0071377=TAS, GO:0008543=TAS, GO:0005887=TAS, GO:0045087=TAS, GO:0006833=TAS, GO:0007189=TAS, GO:0034199=TAS, GO:0009190=IEA} activation of phospholipase C activity, activation of protein kinase A activity, adenylate cyclase-activating G-protein coupled receptor signaling pathway, adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway, cellular response to glucagon stimulus, cyclic nucleotide biosynthetic process, energy reserve metabolic process, epidermal growth factor receptor signaling pathway, fibroblast growth factor receptor signaling pathway, innate immune response, intracellular signal transduction, neurotrophin TRK receptor signaling pathway, signal transduction, small molecule metabolic process, synaptic transmission, transmembrane transport, water transport integral to plasma membrane, plasma membrane ATP binding, adenylate cyclase activity, metal ion binding, phosphorus-oxygen lyase activity Human ADCYAP1 BHF-UCL UniProtKB {GO:0032755=GO_REF:0000019, GO:0060124=GO_REF:0000019, GO:0008284=GO_REF:0000019, GO:0070445=GO_REF:0000019, GO:0034259=GO_REF:0000019, GO:0045471=GO_REF:0000019, GO:0021983=GO_REF:0000019, GO:0002865=GO_REF:0000019, GO:0016521=PMID:9603988, GO:0007267=PMID:2302217, GO:0043267=GO_REF:0000019, GO:0031858=GO_REF:0000019, GO:0051428=PMID:17470806, GO:0007204=GO_REF:0000019, GO:0005615=GO_REF:0000019, GO:0032880=PMID:9603988, GO:0007190=Reactome:REACT_11046, GO:0001541=GO_REF:0000019, GO:0042594=GO_REF:0000019, GO:0043195=GO_REF:0000019, GO:0045909=GO_REF:0000019, GO:0001662=GO_REF:0000019, GO:0005184=PMID:2302217, GO:0048011=Reactome:REACT_11061, GO:0007565=PMID:10698193, GO:0046034=GO_REF:0000019, GO:0001821=GO_REF:0000019, GO:0002878=GO_REF:0000019, GO:0051968=GO_REF:0000019, GO:0005102=PMID:7680413, GO:0090274=GO_REF:0000019, GO:0010579=PMID:9603988, GO:0005576=Reactome:REACT_22268, GO:0060078=GO_REF:0000019, GO:0060253=GO_REF:0000019, GO:0045786=GO_REF:0000019, GO:0019233=GO_REF:0000019, GO:0071385=GO_REF:0000019, GO:0008277=PMID:11175907, GO:0010976=GO_REF:0000019, GO:0005057=GO_REF:0000019, GO:0007169=Reactome:REACT_11064} P18509 Pituitary adenylate cyclase-activating polypeptide protein 20120323 {GO:0032755=IEA, GO:0060124=IEA, GO:0008284=IEA, GO:0070445=IEA, GO:0034259=IEA, GO:0045471=IEA, GO:0021983=IEA, GO:0002865=IEA, GO:0016521=IDA, GO:0007267=TAS, GO:0043267=IEA, GO:0031858=IEA, GO:0051428=IPI, GO:0007204=IEA, GO:0005615=IEA, GO:0032880=IDA, GO:0007190=TAS, GO:0001541=IEA, GO:0042594=IEA, GO:0043195=IEA, GO:0045909=IEA, GO:0001662=IEA, GO:0005184=TAS, GO:0048011=TAS, GO:0007565=TAS, GO:0046034=IEA, GO:0001821=IEA, GO:0002878=IEA, GO:0051968=IEA, GO:0005102=IPI, GO:0090274=IEA, GO:0010579=IDA, GO:0005576=TAS, GO:0060078=IEA, GO:0060253=IEA, GO:0045786=IEA, GO:0019233=IEA, GO:0071385=IEA, GO:0008277=IDA, GO:0010976=IEA, GO:0005057=IEA, GO:0007169=TAS} ATP metabolic process, activation of adenylate cyclase activity, behavioral fear response, cell-cell signaling, cellular response to glucocorticoid stimulus, elevation of cytosolic calcium ion concentration, female pregnancy, histamine secretion, negative regulation of Rho GTPase activity, negative regulation of acute inflammatory response to antigenic stimulus, negative regulation of acute inflammatory response to non-antigenic stimulus, negative regulation of cell cycle, negative regulation of glial cell proliferation, negative regulation of potassium ion transport, neurotrophin TRK receptor signaling pathway, ovarian follicle development, pituitary gland development, positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway, positive regulation of cell proliferation, positive regulation of growth hormone secretion, positive regulation of interleukin-6 production, positive regulation of neuron projection development, positive regulation of somatostatin secretion, positive regulation of synaptic transmission, glutamatergic, positive regulation of vasodilation, regulation of G-protein coupled receptor protein signaling pathway, regulation of oligodendrocyte progenitor proliferation, regulation of postsynaptic membrane potential, regulation of protein localization, response to ethanol, response to starvation, sensory perception of pain, transmembrane receptor protein tyrosine kinase signaling pathway extracellular region, extracellular space, terminal bouton neuropeptide hormone activity, peptide hormone receptor binding, pituitary adenylate cyclase activating polypeptide activity, pituitary adenylate cyclase-activating polypeptide receptor binding, receptor binding, receptor signaling protein activity Human ADCYAP1R1 Reactome UniProtKB {GO:0005515=PMID:17470806, GO:0043005=GO_REF:0000019, GO:0030306=GO_REF:0000019, GO:0005886=Reactome:REACT_22268, GO:0010524=GO_REF:0000019, GO:0045471=GO_REF:0000019, GO:0030819=GO_REF:0000019, GO:0060732=GO_REF:0000019, GO:0007202=GO_REF:0000019, GO:0007283=GO_REF:0000037, GO:0030154=GO_REF:0000037, GO:0007190=Reactome:REACT_11046, GO:0004999=GO_REF:0000002, GO:0060548=GO_REF:0000019, GO:0004872=PMID:7902709, GO:0032355=GO_REF:0000019, GO:0005791=GO_REF:0000019, GO:0046545=GO_REF:0000019, GO:0048011=Reactome:REACT_11061, GO:0009986=GO_REF:0000019, GO:0008179=GO_REF:0000019, GO:0042493=GO_REF:0000019, GO:0033555=GO_REF:0000019, GO:0042923=GO_REF:0000019, GO:0005887=PMID:7902709, GO:0005901=GO_REF:0000019, GO:0019933=GO_REF:0000019, GO:0005923=GO_REF:0000019, GO:0016021=GO_REF:0000038, GO:0007169=Reactome:REACT_11064, GO:0007166=PMID:7902709, GO:0005768=GO_REF:0000019} P41586 Pituitary adenylate cyclase-activating polypeptide type I receptor protein 20060921 {GO:0005515=IPI, GO:0043005=IEA, GO:0030306=IEA, GO:0005886=TAS, GO:0010524=IEA, GO:0045471=IEA, GO:0030819=IEA, GO:0060732=IEA, GO:0007202=IEA, GO:0007283=IEA, GO:0030154=IEA, GO:0007190=TAS, GO:0004999=IEA, GO:0060548=IEA, GO:0004872=TAS, GO:0032355=IEA, GO:0005791=IEA, GO:0046545=IEA, GO:0048011=TAS, GO:0009986=IEA, GO:0008179=IEA, GO:0042493=IEA, GO:0033555=IEA, GO:0042923=IEA, GO:0005887=TAS, GO:0005901=IEA, GO:0019933=IEA, GO:0005923=IEA, GO:0016021=IEA, GO:0007169=TAS, GO:0007166=TAS, GO:0005768=IEA} activation of adenylate cyclase activity, activation of phospholipase C activity, cAMP-mediated signaling, cell differentiation, cell surface receptor signaling pathway, development of primary female sexual characteristics, multicellular organismal response to stress, negative regulation of cell death, neurotrophin TRK receptor signaling pathway, positive regulation of cAMP biosynthetic process, positive regulation of calcium ion transport into cytosol, positive regulation of inositol phosphate biosynthetic process, response to drug, response to estradiol stimulus, response to ethanol, spermatogenesis, transmembrane receptor protein tyrosine kinase signaling pathway caveola, cell surface, endosome, integral to membrane, integral to plasma membrane, neuron projection, plasma membrane, rough endoplasmic reticulum, tight junction ADP-ribosylation factor binding, adenylate cyclase binding, neuropeptide binding, protein binding, receptor activity, vasoactive intestinal polypeptide receptor activity Human ADD1 InterPro UniProtKB {GO:0005516=GO_REF:0000037, GO:0048471=GO_REF:0000019, GO:0030036=PMID:3693401, GO:0020027=GO_REF:0000019, GO:0005886=GO_REF:0000039, GO:0071300=GO_REF:0000019, GO:0005634=PMID:16289097, GO:0042803=PMID:7642559, GO:0046872=GO_REF:0000002, GO:0006921=Reactome:REACT_995, GO:0032092=PMID:7642559, GO:0006884=GO_REF:0000019, GO:0005829=Reactome:REACT_115808, GO:0030968=Reactome:REACT_18356, GO:0045807=GO_REF:0000019, GO:0051016=PMID:8626479, GO:0042608=GO_REF:0000019, GO:0051015=PMID:7642559, GO:0048873=GO_REF:0000019, GO:0035264=GO_REF:0000019, GO:0051017=PMID:3693401, GO:0046982=PMID:7642559, GO:0030507=PMID:7642559, GO:0014069=GO_REF:0000019, GO:0006915=Reactome:REACT_578, GO:0003779=PMID:1840603, GO:0001701=GO_REF:0000019, GO:0045766=GO_REF:0000019, GO:0000902=GO_REF:0000019, GO:0016020=GO_REF:0000019, GO:0005198=GO_REF:0000019, GO:0030218=GO_REF:0000019, GO:0008290=PMID:8626479, GO:0006987=Reactome:REACT_18368, GO:0044267=Reactome:REACT_17015, GO:0008134=PMID:16289097} Q86XM2 ADD1 protein protein 20130413 {GO:0005516=IEA, GO:0048471=IEA, GO:0030036=IC, GO:0020027=IEA, GO:0005886=IEA, GO:0071300=IEA, GO:0005634=IDA, GO:0042803=IPI, GO:0046872=IEA, GO:0006921=TAS, GO:0032092=IDA, GO:0006884=IEA, GO:0005829=TAS, GO:0030968=TAS, GO:0045807=IEA, GO:0051016=IDA, GO:0042608=IEA, GO:0051015=IDA, GO:0048873=IEA, GO:0035264=IEA, GO:0051017=IDA, GO:0046982=IPI, GO:0030507=IDA, GO:0014069=IEA, GO:0006915=TAS, GO:0003779=TAS, GO:0001701=IEA, GO:0045766=IEA, GO:0000902=IEA, GO:0016020=IEA, GO:0005198=IEA, GO:0030218=IEA, GO:0008290=IDA, GO:0006987=TAS, GO:0044267=TAS, GO:0008134=IPI} actin cytoskeleton organization, actin filament bundle assembly, activation of signaling protein activity involved in unfolded protein response, apoptotic process, barbed-end actin filament capping, cell morphogenesis, cell volume homeostasis, cellular component disassembly involved in execution phase of apoptosis, cellular protein metabolic process, cellular response to retinoic acid, endoplasmic reticulum unfolded protein response, erythrocyte differentiation, hemoglobin metabolic process, homeostasis of number of cells within a tissue, in utero embryonic development, multicellular organism growth, positive regulation of angiogenesis, positive regulation of endocytosis, positive regulation of protein binding F-actin capping protein complex, cytosol, membrane, nucleus, perinuclear region of cytoplasm, plasma membrane, postsynaptic density T cell receptor binding, actin binding, actin filament binding, calmodulin binding, metal ion binding, protein heterodimerization activity, protein homodimerization activity, spectrin binding, structural molecule activity, transcription factor binding Human InterPro:IPR001303 ADD2 BHF-UCL UniProtKB {GO:0030097=GO_REF:0000019, GO:0005516=GO_REF:0000037, GO:0030036=PMID:3693401, GO:0005886=GO_REF:0000039, GO:0046982=PMID:7642559, GO:0030507=PMID:7642559, GO:0003779=PMID:1840603, GO:0042803=PMID:7642559, GO:0046872=GO_REF:0000002, GO:0032092=PMID:7642559, GO:0005737=GO_REF:0000037, GO:0051016=PMID:8626479, GO:0051015=PMID:7642559, GO:0016020=GO_REF:0000019, GO:0005198=GO_REF:0000019, GO:0008290=PMID:8626479, GO:0051017=PMID:3693401} P35612 Beta-adducin protein 20090205 {GO:0030097=IEA, GO:0005516=IEA, GO:0030036=IC, GO:0005886=IEA, GO:0046982=IPI, GO:0030507=IDA, GO:0003779=TAS, GO:0042803=IPI, GO:0046872=IEA, GO:0032092=IDA, GO:0005737=IEA, GO:0051016=IDA, GO:0051015=IDA, GO:0016020=IEA, GO:0005198=IEA, GO:0008290=IDA, GO:0051017=IDA} actin cytoskeleton organization, actin filament bundle assembly, barbed-end actin filament capping, hemopoiesis, positive regulation of protein binding F-actin capping protein complex, cytoplasm, membrane, plasma membrane actin binding, actin filament binding, calmodulin binding, metal ion binding, protein heterodimerization activity, protein homodimerization activity, spectrin binding, structural molecule activity Human ADD3 PINC UniProtKB {GO:0005516=GO_REF:0000037, GO:0000794=GO_REF:0000019, GO:0016020=PMID:8893809, GO:0005886=GO_REF:0000039, GO:0005911=GO_REF:0000019, GO:0005200=PMID:8893809, GO:0003779=GO_REF:0000037, GO:0005856=GO_REF:0000039, GO:0005938=GO_REF:0000019, GO:0046872=GO_REF:0000002} Q9UEY8 Gamma-adducin protein 20030904 {GO:0005516=IEA, GO:0000794=IEA, GO:0016020=TAS, GO:0005886=IEA, GO:0005911=IEA, GO:0005200=TAS, GO:0003779=IEA, GO:0005856=IEA, GO:0005938=IEA, GO:0046872=IEA} cell cortex, cell-cell junction, condensed nuclear chromosome, cytoskeleton, membrane, plasma membrane actin binding, calmodulin binding, metal ion binding, structural constituent of cytoskeleton Human ADH1A Reactome UniProtKB {GO:0004022=Reactome:REACT_121302, GO:0005515=PMID:16153155, GO:0006805=Reactome:REACT_13705, GO:0017144=Reactome:REACT_121388, GO:0006066=PMID:2347582, GO:0006069=Reactome:REACT_34, GO:0004024=PMID:9982, GO:0008270=GO_REF:0000002, GO:0044281=Reactome:REACT_111217, GO:0005829=Reactome:REACT_121302} P07327 Alcohol dehydrogenase 1A protein 20130213 {GO:0004022=TAS, GO:0005515=IPI, GO:0006805=TAS, GO:0017144=TAS, GO:0006066=NAS, GO:0006069=TAS, GO:0004024=IDA, GO:0008270=IEA, GO:0044281=TAS, GO:0005829=TAS} alcohol metabolic process, drug metabolic process, ethanol oxidation, small molecule metabolic process, xenobiotic metabolic process cytosol alcohol dehydrogenase (NAD) activity, alcohol dehydrogenase activity, zinc-dependent, protein binding, zinc ion binding Human ADH1B Reactome UniProtKB {GO:0006805=Reactome:REACT_13705, GO:0004024=PMID:9982, GO:0006069=Reactome:REACT_34, GO:0016491=GO_REF:0000038, GO:0008270=PMID:9982, GO:0044281=Reactome:REACT_111217, GO:0005829=Reactome:REACT_1431} P00325 Alcohol dehydrogenase 1B protein 20130213 {GO:0006805=TAS, GO:0004024=IDA, GO:0006069=TAS, GO:0016491=IEA, GO:0008270=IDA, GO:0044281=TAS, GO:0005829=TAS} ethanol oxidation, small molecule metabolic process, xenobiotic metabolic process cytosol alcohol dehydrogenase activity, zinc-dependent, oxidoreductase activity, zinc ion binding Human ADH1C Reactome UniProtKB {GO:0004022=PMID:6391957, GO:0006805=Reactome:REACT_13705, GO:0006069=Reactome:REACT_34, GO:0008270=GO_REF:0000002, GO:0044281=Reactome:REACT_111217, GO:0005829=Reactome:REACT_1431} P00326 Alcohol dehydrogenase 1C protein 20130213 {GO:0004022=IDA, GO:0006805=TAS, GO:0006069=TAS, GO:0008270=IEA, GO:0044281=TAS, GO:0005829=TAS} ethanol oxidation, small molecule metabolic process, xenobiotic metabolic process cytosol alcohol dehydrogenase (NAD) activity, zinc ion binding Human ADH4 HPA UniProtKB {GO:0005503=PMID:15369820, GO:0006805=Reactome:REACT_13705, GO:0006066=PMID:3466164, GO:0006069=Reactome:REACT_34, GO:0006081=PMID:3466164, GO:0044281=Reactome:REACT_111217, GO:0046164=GO_REF:0000024, GO:0003960=GO_REF:0000024, GO:0001523=PMID:15369820, GO:0019841=PMID:10407146, GO:0042375=GO_REF:0000024, GO:0005829=Reactome:REACT_1431, GO:0004022=PMID:3466164, GO:0004032=GO_REF:0000019, GO:0051287=PMID:10407146, GO:0019115=PMID:3466164, GO:0004024=PMID:10407146, GO:0015630=GO_REF:0000052, GO:0042572=PMID:16787387, GO:0016620=PMID:3466164, GO:0016491=GO_REF:0000002, GO:0008270=PMID:10407146, GO:0004745=PMID:15369820} P08319 Alcohol dehydrogenase 4 protein 20100326 {GO:0005503=IDA, GO:0006805=TAS, GO:0006066=IDA, GO:0006069=TAS, GO:0006081=IDA, GO:0044281=TAS, GO:0046164=ISS, GO:0003960=ISS, GO:0001523=IDA, GO:0019841=IDA, GO:0042375=ISS, GO:0005829=TAS, GO:0004022=IDA, GO:0004032=IEA, GO:0051287=IDA, GO:0019115=IDA, GO:0004024=IDA, GO:0015630=IDA, GO:0042572=IDA, GO:0016620=IDA, GO:0016491=IEA, GO:0008270=IDA, GO:0004745=IDA} alcohol catabolic process, alcohol metabolic process, cellular aldehyde metabolic process, ethanol oxidation, quinone cofactor metabolic process, retinoid metabolic process, retinol metabolic process, small molecule metabolic process, xenobiotic metabolic process cytosol, microtubule cytoskeleton NAD binding, NADPH:quinone reductase activity, alcohol dehydrogenase (NAD) activity, alcohol dehydrogenase activity, zinc-dependent, alditol:NADP+ 1-oxidoreductase activity, all-trans retinal binding, benzaldehyde dehydrogenase activity, oxidoreductase activity, oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor, retinol binding, retinol dehydrogenase activity, zinc ion binding Human ADH5 UniProtKB UniProtKB {GO:0005504=PMID:8460164, GO:0006069=GO_REF:0000002, GO:0006068=GO_REF:0000019, GO:0007568=GO_REF:0000019, GO:0009055=PMID:8460164, GO:0005634=GO_REF:0000019, GO:0051409=GO_REF:0000019, GO:0018119=GO_REF:0000019, GO:0045777=GO_REF:0000019, GO:0001523=GO_REF:0000019, GO:0042803=GO_REF:0000019, GO:0004022=GO_REF:0000003, GO:0005739=GO_REF:0000019, GO:0003016=GO_REF:0000019, GO:0046294=GO_REF:0000019, GO:0051903=PMID:8460164, GO:0016491=GO_REF:0000038, GO:0032496=GO_REF:0000019, GO:0051775=PMID:8460164, GO:0018467=PMID:8460164, GO:0008270=PMID:6375718} P11766 Alcohol dehydrogenase class-3 protein 20080612 {GO:0005504=IDA, GO:0006069=IEA, GO:0006068=IEA, GO:0007568=IEA, GO:0009055=TAS, GO:0005634=IEA, GO:0051409=IEA, GO:0018119=IEA, GO:0045777=IEA, GO:0001523=IEA, GO:0042803=IEA, GO:0004022=IEA, GO:0005739=IEA, GO:0003016=IEA, GO:0046294=IEA, GO:0051903=TAS, GO:0016491=IEA, GO:0032496=IEA, GO:0051775=IDA, GO:0018467=IDA, GO:0008270=IDA} aging, ethanol catabolic process, ethanol oxidation, formaldehyde catabolic process, peptidyl-cysteine S-nitrosylation, positive regulation of blood pressure, respiratory system process, response to lipopolysaccharide, response to nitrosative stress, response to redox state, retinoid metabolic process mitochondrion, nucleus S-(hydroxymethyl)glutathione dehydrogenase activity, alcohol dehydrogenase (NAD) activity, electron carrier activity, fatty acid binding, formaldehyde dehydrogenase activity, oxidoreductase activity, protein homodimerization activity, zinc ion binding Human ADH6 Reactome UniProtKB {GO:0004022=PMID:1755855, GO:0006805=Reactome:REACT_13705, GO:0006069=Reactome:REACT_34, GO:0045471=PMID:1755855, GO:0016491=GO_REF:0000002, GO:0008270=PMID:1593644, GO:0044281=Reactome:REACT_111217, GO:0005575=GO_REF:0000015, GO:0005829=Reactome:REACT_1431} P28332 Alcohol dehydrogenase 6 protein 20130213 {GO:0004022=IDA, GO:0006805=TAS, GO:0006069=TAS, GO:0045471=IDA, GO:0016491=IEA, GO:0008270=NAS, GO:0044281=TAS, GO:0005575=ND, GO:0005829=TAS} ethanol oxidation, response to ethanol, small molecule metabolic process, xenobiotic metabolic process cellular_component, cytosol alcohol dehydrogenase (NAD) activity, oxidoreductase activity, zinc ion binding Human ADH7 GOC UniProtKB {GO:0006805=Reactome:REACT_13705, GO:0045471=PMID:9600267, GO:0044281=Reactome:REACT_111217, GO:0019841=PMID:9228021, GO:0005829=Reactome:REACT_1431, GO:0004022=PMID:8074657, GO:0005622=GO_REF:0000019, GO:0009617=PMID:11410738, GO:0005737=GO_REF:0000052, GO:0042573=GO_REF:0000019, GO:0004024=PMID:7876099, GO:0042572=GO_REF:0000019, GO:0004745=PMID:7876099, GO:0048019=PMID:9600267, GO:0010430=PMID:9600267, GO:0006069=Reactome:REACT_34, GO:0006068=GO_REF:0000019, GO:0005730=GO_REF:0000052, GO:0005576=PMID:9600267, GO:0001523=PMID:9600267, GO:0004031=PMID:9600267, GO:0035276=PMID:9228021, GO:1900116=PMID:9600267, GO:0008270=GO_REF:0000002, GO:0055114=PMID:7876099} P40394 Alcohol dehydrogenase class 4 mu/sigma chain protein 20130413 {GO:0006805=TAS, GO:0045471=IDA, GO:0044281=TAS, GO:0019841=IDA, GO:0005829=TAS, GO:0004022=TAS, GO:0005622=IEA, GO:0009617=IDA, GO:0005737=IDA, GO:0042573=IEA, GO:0004024=IDA, GO:0042572=IEA, GO:0004745=IDA, GO:0048019=IDA, GO:0010430=IDA, GO:0006069=TAS, GO:0006068=IEA, GO:0005730=IDA, GO:0005576=IDA, GO:0001523=IDA, GO:0004031=IDA, GO:0035276=IDA, GO:1900116=IDA, GO:0008270=IEA, GO:0055114=IDA} ethanol catabolic process, ethanol oxidation, extracellular negative regulation of signal transduction, fatty acid omega-oxidation, oxidation-reduction process, response to bacterium, response to ethanol, retinoic acid metabolic process, retinoid metabolic process, retinol metabolic process, small molecule metabolic process, xenobiotic metabolic process cytoplasm, cytosol, extracellular region, intracellular, nucleolus alcohol dehydrogenase (NAD) activity, alcohol dehydrogenase activity, zinc-dependent, aldehyde oxidase activity, ethanol binding, receptor antagonist activity, retinol binding, retinol dehydrogenase activity, zinc ion binding Human ADHFE1 Reactome UniProtKB {GO:0005739=GO_REF:0000024, GO:0047988=PMID:16435184, GO:0005759=Reactome:REACT_25102, GO:0006103=Reactome:REACT_25367, GO:0016491=GO_REF:0000002, GO:0044281=Reactome:REACT_111217, GO:0015993=PMID:16435184, GO:0046872=GO_REF:0000002} Q8IWW8 Hydroxyacid-oxoacid transhydrogenase, mitochondrial protein 20130301 {GO:0005739=ISS, GO:0047988=IDA, GO:0005759=TAS, GO:0006103=TAS, GO:0016491=IEA, GO:0044281=TAS, GO:0015993=IDA, GO:0046872=IEA} 2-oxoglutarate metabolic process, molecular hydrogen transport, small molecule metabolic process mitochondrial matrix, mitochondrion hydroxyacid-oxoacid transhydrogenase activity, metal ion binding, oxidoreductase activity Human ADI1 HPA UniProtKB {GO:0005515=PMID:14718544, GO:0005794=GO_REF:0000052, GO:0005886=PMID:14718544, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0044281=Reactome:REACT_111217, GO:0046872=GO_REF:0000037, GO:0005829=Reactome:REACT_75861, GO:0034641=Reactome:REACT_13, GO:0005737=PMID:11602742, GO:0000096=Reactome:REACT_115639, GO:0019509=Reactome:REACT_75881, GO:0006595=Reactome:REACT_14820, GO:0016491=PMID:15938715, GO:0010309=Reactome:REACT_75861} Q9BV57 1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase protein 20110516 {GO:0005515=IPI, GO:0005794=IDA, GO:0005886=IDA, GO:0005730=IDA, GO:0005634=IDA, GO:0044281=TAS, GO:0046872=IEA, GO:0005829=TAS, GO:0034641=TAS, GO:0005737=IDA, GO:0000096=TAS, GO:0019509=TAS, GO:0006595=TAS, GO:0016491=IDA, GO:0010309=TAS} L-methionine salvage from methylthioadenosine, cellular nitrogen compound metabolic process, polyamine metabolic process, small molecule metabolic process, sulfur amino acid metabolic process Golgi apparatus, cytoplasm, cytosol, nucleolus, nucleus, plasma membrane "acireductone dioxygenase iron(II)-requiring"" activity, metal ion binding, oxidoreductase activity, protein binding""" Human ADIPOQ BHF-UCL UniProtKB {GO:0005515=PMID:12070119, GO:0043499=PMID:10982546, GO:0045599=PMID:12021245, GO:0033211=GO_REF:0000019, GO:0050731=GO_REF:0000019, GO:0006091=PMID:10095105, GO:0010739=PMID:10982546, GO:0005615=PMID:10403784, GO:0042803=PMID:12021245, GO:0010906=PMID:17327472, GO:0032757=PMID:19524870, GO:0042802=PMID:10961870, GO:0070208=GO_REF:0000019, GO:0046888=GO_REF:0000019, GO:0045923=PMID:12368907, GO:0071639=PMID:19524870, GO:0009744=GO_REF:0000019, GO:0046326=PMID:12368907, GO:0034115=PMID:10604883, GO:2000461=PMID:12070119, GO:0051260=GO_REF:0000024, GO:0070373=PMID:12070119, GO:0033691=PMID:19855092, GO:0033034=PMID:10961870, GO:0043123=GO_REF:0000024, GO:0043124=PMID:10982546, GO:2000481=PMID:19524870, GO:2000467=GO_REF:0000024, GO:0030336=GO_REF:0000024, GO:0019395=GO_REF:0000024, GO:0032869=GO_REF:0000024, GO:0006635=PMID:12368907, GO:0010745=PMID:11222466, GO:0032720=PMID:10961870, GO:0051384=GO_REF:0000019, GO:0005125=PMID:12611609, GO:0010804=PMID:10604883, GO:0045650=PMID:10961870, GO:0032270=PMID:18703020, GO:0070543=GO_REF:0000019, GO:0060081=GO_REF:0000019, GO:0070994=GO_REF:0000024, GO:0005179=PMID:11222466, GO:0071872=GO_REF:0000019, GO:0050873=GO_REF:0000024, GO:0090317=PMID:18431508, GO:0050805=PMID:17327472, GO:2000279=PMID:12070119, GO:0007623=GO_REF:0000019, GO:2000478=GO_REF:0000024, GO:0045892=PMID:18431508, GO:0005581=GO_REF:0000037, GO:0051899=GO_REF:0000019, GO:0005783=GO_REF:0000024, GO:0045471=GO_REF:0000019, GO:2000534=PMID:18431508, GO:0045776=PMID:17327472, GO:0045777=GO_REF:0000019, GO:0010875=PMID:18703020, GO:0014912=PMID:12070119, GO:0031953=PMID:12070119, GO:0050765=PMID:10961870, GO:0034383=PMID:11222466, GO:0043407=GO_REF:0000024, GO:0030853=PMID:10961870, GO:0006006=PMID:12368907, GO:0010642=PMID:12070119, GO:0045721=PMID:12368907, GO:0001666=GO_REF:0000019, GO:0014823=GO_REF:0000019, GO:2000584=GO_REF:0000024, GO:0007584=GO_REF:0000019, GO:0005102=PMID:12368907, GO:0009967=PMID:12368907, GO:0045715=PMID:11222466, GO:0005576=Reactome:REACT_27292, GO:0048662=PMID:12070119, GO:0042593=PMID:12368907, GO:0035690=GO_REF:0000024, GO:0072659=PMID:18431508, GO:0009749=PMID:12368907, GO:0050728=PMID:12611609, GO:2000590=GO_REF:0000024, GO:0001934=PMID:18431508, GO:0034612=PMID:10604883, GO:0071320=GO_REF:0000019} Q15848 Adiponectin protein 20090424 {GO:0005515=IPI, GO:0043499=IDA, GO:0045599=IDA, GO:0033211=IEA, GO:0050731=IEA, GO:0006091=TAS, GO:0010739=IDA, GO:0005615=IDA, GO:0042803=IPI, GO:0010906=IDA, GO:0032757=IDA, GO:0042802=TAS, GO:0070208=IEA, GO:0046888=IEA, GO:0045923=ISS, GO:0071639=IDA, GO:0009744=IEA, GO:0046326=ISS, GO:0034115=IDA, GO:2000461=IDA, GO:0051260=ISS, GO:0070373=IDA, GO:0033691=IDA, GO:0033034=IDA, GO:0043123=ISS, GO:0043124=IDA, GO:2000481=IDA, GO:2000467=ISS, GO:0030336=ISS, GO:0019395=ISS, GO:0032869=ISS, GO:0006635=ISS, GO:0010745=IDA, GO:0032720=IDA, GO:0051384=IEA, GO:0005125=NAS, GO:0010804=IDA, GO:0045650=IDA, GO:0032270=IDA, GO:0070543=IEA, GO:0060081=IEA, GO:0070994=ISS, GO:0005179=IDA, GO:0071872=IEA, GO:0050873=ISS, GO:0090317=IDA, GO:0050805=IDA, GO:2000279=IDA, GO:0007623=IEA, GO:2000478=ISS, GO:0045892=IDA, GO:0005581=IEA, GO:0051899=IEA, GO:0005783=ISS, GO:0045471=IEA, GO:2000534=IDA, GO:0045776=IDA, GO:0045777=IEA, GO:0010875=IDA, GO:0014912=IDA, GO:0031953=IDA, GO:0050765=IDA, GO:0034383=IDA, GO:0043407=ISS, GO:0030853=IDA, GO:0006006=ISS, GO:0010642=IDA, GO:0045721=ISS, GO:0001666=IEA, GO:0014823=IEA, GO:2000584=ISS, GO:0007584=IEA, GO:0005102=ISS, GO:0009967=ISS, GO:0045715=IDA, GO:0005576=TAS, GO:0048662=IDA, GO:0042593=ISS, GO:0035690=ISS, GO:0072659=IDA, GO:0009749=ISS, GO:0050728=NAS, GO:2000590=ISS, GO:0001934=IDA, GO:0034612=IDA, GO:0071320=IEA} adiponectin-mediated signaling pathway, brown fat cell differentiation, cellular response to cAMP, cellular response to drug, cellular response to epinephrine stimulus, cellular response to insulin stimulus, circadian rhythm, detection of oxidative stress, fatty acid beta-oxidation, fatty acid oxidation, generation of precursor metabolites and energy, glucose homeostasis, glucose metabolic process, low-density lipoprotein particle clearance, membrane depolarization, membrane hyperpolarization, negative regulation of DNA biosynthetic process, negative regulation of ERK1 and ERK2 cascade, negative regulation of I-kappaB kinase/NF-kappaB cascade, negative regulation of MAP kinase activity, negative regulation of blood pressure, negative regulation of cell migration, negative regulation of eukaryotic cell surface binding, negative regulation of fat cell differentiation, negative regulation of gluconeogenesis, negative regulation of granulocyte differentiation, negative regulation of heterotypic cell-cell adhesion, negative regulation of hormone secretion, negative regulation of inflammatory response, negative regulation of intracellular protein transport, negative regulation of low-density lipoprotein particle receptor biosynthetic process, negative regulation of macrophage derived foam cell differentiation, negative regulation of macrophage differentiation, negative regulation of metanephric mesenchymal cell migration, negative regulation of phagocytosis, negative regulation of platelet-derived growth factor receptor signaling pathway, negative regulation of platelet-derived growth factor receptor-alpha signaling pathway, negative regulation of protein autophosphorylation, negative regulation of smooth muscle cell migration, negative regulation of smooth muscle cell proliferation, negative regulation of synaptic transmission, negative regulation of transcription, DNA-dependent, negative regulation of tumor necrosis factor production, negative regulation of tumor necrosis factor-mediated signaling pathway, positive regulation of I-kappaB kinase/NF-kappaB cascade, positive regulation of blood pressure, positive regulation of cAMP-dependent protein kinase activity, positive regulation of cellular protein metabolic process, positive regulation of cholesterol efflux, positive regulation of fatty acid metabolic process, positive regulation of glucose import, positive regulation of glycogen (starch) synthase activity, positive regulation of interleukin-8 production, positive regulation of metanephric glomerular visceral epithelial cell development, positive regulation of monocyte chemotactic protein-1 production, positive regulation of myeloid cell apoptotic process, positive regulation of peptidyl-tyrosine phosphorylation, positive regulation of protein kinase A signaling cascade, positive regulation of protein phosphorylation, positive regulation of renal albumin absorption, positive regulation of signal transduction, protein heterotrimerization, protein homooligomerization, protein localization to plasma membrane, regulation of glucose metabolic process, response to activity, response to ethanol, response to glucocorticoid stimulus, response to glucose stimulus, response to hypoxia, response to linoleic acid, response to nutrient, response to sucrose stimulus, response to tumor necrosis factor collagen, endoplasmic reticulum, extracellular region, extracellular space cytokine activity, eukaryotic cell surface binding, hormone activity, identical protein binding, protein binding, protein homodimerization activity, receptor binding, sialic acid binding Human ADIPOR1 BHF-UCL UniProtKB {GO:0019395=PMID:12802337, GO:0009755=PMID:12802337, GO:0019901=PMID:19233263, GO:0005886=PMID:19233263, GO:0046982=GO_REF:0000019, GO:0042562=PMID:12802337, GO:0004872=GO_REF:0000019, GO:0016021=PMID:12802337, GO:0042802=GO_REF:0000019} Q96A54 Adiponectin receptor protein 1 protein 20100202 {GO:0019395=IDA, GO:0009755=IDA, GO:0019901=IPI, GO:0005886=IDA, GO:0046982=IEA, GO:0042562=IDA, GO:0004872=IEA, GO:0016021=NAS, GO:0042802=IEA} fatty acid oxidation, hormone-mediated signaling pathway integral to membrane, plasma membrane hormone binding, identical protein binding, protein heterodimerization activity, protein kinase binding, receptor activity Human UniProtKB:P67870 ADIPOR2 UniProtKB UniProtKB {GO:0019395=PMID:12802337, GO:0009755=PMID:12802337, GO:0046982=GO_REF:0000019, GO:0042562=PMID:12802337, GO:0004872=GO_REF:0000019, GO:0016021=GO_REF:0000037, GO:0042802=GO_REF:0000019} Q86V24 Adiponectin receptor protein 2 protein 20041006 {GO:0019395=ISS, GO:0009755=ISS, GO:0046982=IEA, GO:0042562=ISS, GO:0004872=IEA, GO:0016021=IEA, GO:0042802=IEA} fatty acid oxidation, hormone-mediated signaling pathway integral to membrane hormone binding, identical protein binding, protein heterodimerization activity, receptor activity Human UniProtKB:Q96A54 ADK Reactome UniProtKB {GO:0046085=GO_REF:0000019, GO:0055086=Reactome:REACT_1698, GO:0005634=GO_REF:0000019, GO:0044209=GO_REF:0000041, GO:0044281=Reactome:REACT_111217, GO:0005524=GO_REF:0000037, GO:0009156=PMID:9070863, GO:0046872=GO_REF:0000037, GO:0032922=GO_REF:0000019, GO:0005829=Reactome:REACT_1728, GO:0006166=GO_REF:0000019, GO:0044342=GO_REF:0000019, GO:0006144=Reactome:REACT_522, GO:0004001=Reactome:REACT_1728, GO:0042102=GO_REF:0000019, GO:0043101=Reactome:REACT_1923, GO:0016773=GO_REF:0000002, GO:0006175=GO_REF:0000019, GO:0010613=GO_REF:0000019} P55263 Adenosine kinase protein 20130213 {GO:0046085=IEA, GO:0055086=TAS, GO:0005634=IEA, GO:0044209=IEA, GO:0044281=TAS, GO:0005524=IEA, GO:0009156=TAS, GO:0046872=IEA, GO:0032922=IEA, GO:0005829=TAS, GO:0006166=IEA, GO:0044342=IEA, GO:0006144=TAS, GO:0004001=EXP, GO:0042102=IEA, GO:0043101=TAS, GO:0016773=IEA, GO:0006175=IEA, GO:0010613=IEA} AMP salvage, adenosine metabolic process, circadian regulation of gene expression, dATP biosynthetic process, nucleobase-containing small molecule metabolic process, positive regulation of T cell proliferation, positive regulation of cardiac muscle hypertrophy, purine nucleobase metabolic process, purine ribonucleoside salvage, purine-containing compound salvage, ribonucleoside monophosphate biosynthetic process, small molecule metabolic process, type B pancreatic cell proliferation cytosol, nucleus ATP binding, adenosine kinase activity, metal ion binding, phosphotransferase activity, alcohol group as acceptor Human ADM BHF-UCL UniProtKB {GO:0005515=PMID:20074556, GO:0008284=GO_REF:0000019, GO:0008285=GO_REF:0000019, GO:0031700=GO_REF:0000019, GO:0006701=PMID:10822232, GO:2001214=GO_REF:0000019, GO:0060712=GO_REF:0000019, GO:0031102=GO_REF:0000019, GO:0008015=PMID:8074714, GO:0060670=GO_REF:0000019, GO:0009409=GO_REF:0000019, GO:0031100=GO_REF:0000019, GO:0007267=PMID:8074714, GO:0007204=GO_REF:0000019, GO:0005615=PMID:12379507, GO:0031623=PMID:15613468, GO:0007507=GO_REF:0000019, GO:0005737=PMID:12379507, GO:0048589=GO_REF:0000019, GO:0042594=GO_REF:0000019, GO:0045906=PMID:11410113, GO:0045909=GO_REF:0000019, GO:0032496=GO_REF:0000019, GO:0006171=PMID:20074556, GO:0042475=GO_REF:0000019, GO:0001666=GO_REF:0000019, GO:0032868=GO_REF:0000019, GO:0007565=GO_REF:0000019, GO:0008209=GO_REF:0000019, GO:0007568=GO_REF:0000019, GO:0005102=PMID:8524787, GO:0009611=GO_REF:0000019, GO:0001843=GO_REF:0000019, GO:0005576=Reactome:REACT_22268, GO:0051384=GO_REF:0000019, GO:0045766=GO_REF:0000019, GO:0046879=GO_REF:0000019, GO:0007165=PMID:10822232, GO:0005179=GO_REF:0000037, GO:0002026=GO_REF:0000019, GO:0019933=GO_REF:0000019, GO:0010460=GO_REF:0000019, GO:0097084=GO_REF:0000019, GO:0001570=PMID:16964401, GO:0043116=GO_REF:0000019} P35318 ADM protein 20080215 {GO:0005515=IPI, GO:0008284=IEA, GO:0008285=IEA, GO:0031700=IEA, GO:0006701=TAS, GO:2001214=IEA, GO:0060712=IEA, GO:0031102=IEA, GO:0008015=TAS, GO:0060670=IEA, GO:0009409=IEA, GO:0031100=IEA, GO:0007267=TAS, GO:0007204=IEA, GO:0005615=IDA, GO:0031623=IDA, GO:0007507=IEA, GO:0005737=IDA, GO:0048589=IEA, GO:0042594=IEA, GO:0045906=IDA, GO:0045909=IEA, GO:0032496=IEA, GO:0006171=IDA, GO:0042475=IEA, GO:0001666=IEA, GO:0032868=IEA, GO:0007565=IEA, GO:0008209=IEA, GO:0007568=IEA, GO:0005102=TAS, GO:0009611=IEA, GO:0001843=IEA, GO:0005576=TAS, GO:0051384=IEA, GO:0045766=IEA, GO:0046879=IEA, GO:0007165=TAS, GO:0005179=IEA, GO:0002026=IEA, GO:0019933=IEA, GO:0010460=IEA, GO:0097084=IEA, GO:0001570=IDA, GO:0043116=IEA} aging, androgen metabolic process, blood circulation, branching involved in labyrinthine layer morphogenesis, cAMP biosynthetic process, cAMP-mediated signaling, cell-cell signaling, developmental growth, elevation of cytosolic calcium ion concentration, female pregnancy, heart development, hormone secretion, negative regulation of cell proliferation, negative regulation of vascular permeability, negative regulation of vasoconstriction, neural tube closure, neuron projection regeneration, odontogenesis of dentin-containing tooth, organ regeneration, positive regulation of angiogenesis, positive regulation of cell proliferation, positive regulation of heart rate, positive regulation of vasculogenesis, positive regulation of vasodilation, progesterone biosynthetic process, receptor internalization, regulation of the force of heart contraction, response to cold, response to glucocorticoid stimulus, response to hypoxia, response to insulin stimulus, response to lipopolysaccharide, response to starvation, response to wounding, signal transduction, spongiotrophoblast layer development, vascular smooth muscle cell development, vasculogenesis cytoplasm, extracellular region, extracellular space adrenomedullin receptor binding, hormone activity, protein binding, receptor binding Human ADM2 Reactome UniProtKB {GO:0007631=GO_REF:0000019, GO:0005179=GO_REF:0000037, GO:0007586=GO_REF:0000019, GO:0005576=Reactome:REACT_22268, GO:0001525=PMID:20596610, GO:0045776=GO_REF:0000019, GO:0007189=GO_REF:0000019, GO:0032403=PMID:20596610, GO:0045766=PMID:19592612} Q7Z4H4 ADM2 protein 20130213 {GO:0007631=IEA, GO:0005179=IEA, GO:0007586=IEA, GO:0005576=TAS, GO:0001525=IDA, GO:0045776=IEA, GO:0007189=IEA, GO:0032403=IDA, GO:0045766=IDA} adenylate cyclase-activating G-protein coupled receptor signaling pathway, angiogenesis, digestion, feeding behavior, negative regulation of blood pressure, positive regulation of angiogenesis extracellular region hormone activity, protein complex binding Human ADNP HPA UniProtKB {GO:0005515=PMID:21888893, GO:0043565=GO_REF:0000002, GO:0043524=GO_REF:0000019, GO:0003700=GO_REF:0000002, GO:0003682=GO_REF:0000019, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0008270=GO_REF:0000002, GO:0005615=GO_REF:0000019, GO:0006351=GO_REF:0000037} Q9H2P0 Activity-dependent neuroprotector homeobox protein protein 20080818 {GO:0005515=IPI, GO:0043565=IEA, GO:0043524=IEA, GO:0003700=IEA, GO:0003682=IEA, GO:0005730=IDA, GO:0005634=IDA, GO:0008270=IEA, GO:0005615=IEA, GO:0006351=IEA} negative regulation of neuron apoptotic process, transcription, DNA-dependent extracellular space, nucleolus, nucleus chromatin binding, protein binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, zinc ion binding NOT Human ADNP2 IntAct UniProtKB {GO:0005515=PMID:21888893, GO:0003700=GO_REF:0000002, GO:0030307=GO_REF:0000024, GO:0071300=GO_REF:0000024, GO:0005634=GO_REF:0000039, GO:0005575=GO_REF:0000015, GO:0006351=GO_REF:0000037, GO:0043565=GO_REF:0000002, GO:0003674=GO_REF:0000015, GO:0030182=GO_REF:0000024, GO:0060548=GO_REF:0000024, GO:0008270=GO_REF:0000002, GO:0034599=GO_REF:0000024} Q6IQ32 ADNP homeobox protein 2 protein 20130415 {GO:0005515=IPI, GO:0003700=IEA, GO:0030307=ISS, GO:0071300=ISS, GO:0005634=IEA, GO:0005575=ND, GO:0006351=IEA, GO:0043565=IEA, GO:0003674=ND, GO:0030182=ISS, GO:0060548=ISS, GO:0008270=IEA, GO:0034599=ISS} cellular response to oxidative stress, cellular response to retinoic acid, negative regulation of cell death, neuron differentiation, positive regulation of cell growth, transcription, DNA-dependent cellular_component, nucleus molecular_function, protein binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, zinc ion binding Human UniProtKB:P83916 ADO ENSEMBL UniProtKB {GO:0005739=GO_REF:0000019, GO:0047800=GO_REF:0000003, GO:0046872=GO_REF:0000037} Q96SZ5 2-aminoethanethiol dioxygenase protein 20130413 {GO:0005739=IEA, GO:0047800=IEA, GO:0046872=IEA} mitochondrion cysteamine dioxygenase activity, metal ion binding Human Ensembl:ENSMUSP00000075107 ADORA1 IntAct UniProtKB {GO:0005515=PMID:16481441, GO:0006909=PMID:8360491, GO:0001659=GO_REF:0000019, GO:0043268=GO_REF:0000019, GO:0060087=GO_REF:0000019, GO:0046888=GO_REF:0000019, GO:0048167=GO_REF:0000019, GO:0006612=GO_REF:0000019, GO:0045211=GO_REF:0000019, GO:0043025=GO_REF:0000019, GO:0030673=GO_REF:0000019, GO:0045822=GO_REF:0000019, GO:0048786=GO_REF:0000019, GO:0046982=GO_REF:0000019, GO:0051967=GO_REF:0000019, GO:0045741=GO_REF:0000019, GO:0060079=GO_REF:0000019, GO:0014069=GO_REF:0000019, GO:0031683=GO_REF:0000019, GO:0002674=GO_REF:0000019, GO:0016042=GO_REF:0000019, GO:0001609=GO_REF:0000002, GO:0042734=GO_REF:0000019, GO:0005887=PMID:1530647, GO:0001883=GO_REF:0000019, GO:0035814=GO_REF:0000019, GO:0032229=GO_REF:0000019, GO:0055118=GO_REF:0000019, GO:0008285=GO_REF:0000019, GO:0050995=GO_REF:0000019, GO:0005886=Reactome:REACT_22289, GO:0005783=GO_REF:0000019, GO:0014050=GO_REF:0000019, GO:0007267=PMID:7818494, GO:0045776=GO_REF:0000019, GO:0045777=GO_REF:0000019, GO:0007193=GO_REF:0000019, GO:0070256=GO_REF:0000019, GO:0032279=GO_REF:0000019, GO:0016323=GO_REF:0000019, GO:0004629=GO_REF:0000019, GO:0000186=GO_REF:0000019, GO:0002087=GO_REF:0000019, GO:0006954=PMID:8360491, GO:0043195=GO_REF:0000019, GO:0045908=GO_REF:0000019, GO:0050965=GO_REF:0000019, GO:0001666=GO_REF:0000019, GO:0043066=GO_REF:0000019, GO:0001664=GO_REF:0000019, GO:0002793=GO_REF:0000019, GO:0035307=GO_REF:0000019, GO:0032900=GO_REF:0000019, GO:0097190=PMID:7818494, GO:0007399=PMID:8450977, GO:0012505=GO_REF:0000019, GO:0007165=PMID:1530647, GO:0032795=GO_REF:0000019, GO:0042323=GO_REF:0000019, GO:0032244=GO_REF:0000019, GO:0050890=GO_REF:0000019, GO:0003093=GO_REF:0000019, GO:0002686=GO_REF:0000019} P30542 Adenosine receptor A1 protein 20130415 {GO:0005515=IPI, GO:0006909=TAS, GO:0001659=IEA, GO:0043268=IEA, GO:0060087=IEA, GO:0046888=IEA, GO:0048167=IEA, GO:0006612=IEA, GO:0045211=IEA, GO:0043025=IEA, GO:0030673=IEA, GO:0045822=IEA, GO:0048786=IEA, GO:0046982=IEA, GO:0051967=IEA, GO:0045741=IEA, GO:0060079=IEA, GO:0014069=IEA, GO:0031683=IEA, GO:0002674=IEA, GO:0016042=IEA, GO:0001609=IEA, GO:0042734=IEA, GO:0005887=TAS, GO:0001883=IEA, GO:0035814=IEA, GO:0032229=IEA, GO:0055118=IEA, GO:0008285=IEA, GO:0050995=IEA, GO:0005886=TAS, GO:0005783=IEA, GO:0014050=IEA, GO:0007267=TAS, GO:0045776=IEA, GO:0045777=IEA, GO:0007193=IEA, GO:0070256=IEA, GO:0032279=IEA, GO:0016323=IEA, GO:0004629=IEA, GO:0000186=IEA, GO:0002087=IEA, GO:0006954=TAS, GO:0043195=IEA, GO:0045908=IEA, GO:0050965=IEA, GO:0001666=IEA, GO:0043066=IEA, GO:0001664=IEA, GO:0002793=IEA, GO:0035307=IEA, GO:0032900=IEA, GO:0097190=TAS, GO:0007399=TAS, GO:0012505=IEA, GO:0007165=TAS, GO:0032795=IEA, GO:0042323=IEA, GO:0032244=IEA, GO:0050890=IEA, GO:0003093=IEA, GO:0002686=IEA} activation of MAPKK activity, adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway, apoptotic signaling pathway, cell-cell signaling, cognition, detection of temperature stimulus involved in sensory perception of pain, inflammatory response, lipid catabolic process, negative regulation of acute inflammatory response, negative regulation of apoptotic process, negative regulation of blood pressure, negative regulation of cardiac muscle contraction, negative regulation of cell proliferation, negative regulation of circadian sleep/wake cycle, non-REM sleep, negative regulation of glutamate secretion, negative regulation of heart contraction, negative regulation of hormone secretion, negative regulation of leukocyte migration, negative regulation of lipid catabolic process, negative regulation of mucus secretion, negative regulation of neurotrophin production, negative regulation of renal sodium excretion, negative regulation of synaptic transmission, GABAergic, negative regulation of synaptic transmission, glutamatergic, negative regulation of vasodilation, nervous system development, phagocytosis, positive regulation of blood pressure, positive regulation of epidermal growth factor-activated receptor activity, positive regulation of nucleoside transport, positive regulation of peptide secretion, positive regulation of potassium ion transport, positive regulation of protein dephosphorylation, protein targeting to membrane, regulation of excitatory postsynaptic membrane potential, regulation of glomerular filtration, regulation of respiratory gaseous exchange by neurological system process, regulation of synaptic plasticity, relaxation of vascular smooth muscle, response to hypoxia, signal transduction, temperature homeostasis asymmetric synapse, axolemma, basolateral plasma membrane, endomembrane system, endoplasmic reticulum, integral to plasma membrane, neuronal cell body, plasma membrane, postsynaptic density, postsynaptic membrane, presynaptic active zone, presynaptic membrane, terminal bouton G-protein beta/gamma-subunit complex binding, G-protein coupled adenosine receptor activity, G-protein coupled receptor binding, heterotrimeric G-protein binding, phospholipase C activity, protein binding, protein heterodimerization activity, purine nucleoside binding Human UniProtKB:P29274 ADORA2A IntAct UniProtKB {GO:0006909=PMID:8360491, GO:0005515=PMID:19632986, GO:0046636=GO_REF:0000019, GO:0008015=PMID:9262401, GO:0043524=GO_REF:0000019, GO:0048167=GO_REF:0000019, GO:0045211=GO_REF:0000019, GO:0043025=GO_REF:0000019, GO:0051924=GO_REF:0000019, GO:0030673=GO_REF:0000019, GO:0014061=GO_REF:0000019, GO:0048786=GO_REF:0000019, GO:0046982=GO_REF:0000019, GO:0060134=GO_REF:0000019, GO:0051968=GO_REF:0000019, GO:0060079=GO_REF:0000019, GO:0014069=GO_REF:0000019, GO:0007417=PMID:10945659, GO:0032230=GO_REF:0000019, GO:0007271=GO_REF:0000019, GO:0001609=GO_REF:0000019, GO:0042734=GO_REF:0000019, GO:0060080=GO_REF:0000019, GO:0005887=PMID:8794889, GO:0051393=GO_REF:0000019, GO:0035815=GO_REF:0000019, GO:0007188=PMID:10899090, GO:0007189=GO_REF:0000019, GO:0019899=PMID:16339847, GO:0035810=GO_REF:0000019, GO:0008285=GO_REF:0000019, GO:0005886=Reactome:REACT_22268, GO:2001235=GO_REF:0000019, GO:0030819=GO_REF:0000019, GO:0007267=PMID:7818494, GO:0050714=GO_REF:0000019, GO:0014057=GO_REF:0000019, GO:0048143=GO_REF:0000019, GO:0007205=GO_REF:0000019, GO:0032279=GO_REF:0000019, GO:0014049=GO_REF:0000019, GO:0007190=Reactome:REACT_11046, GO:0006954=PMID:8360491, GO:0031000=GO_REF:0000019, GO:0040013=GO_REF:0000019, GO:0042311=GO_REF:0000019, GO:0001963=GO_REF:0000019, GO:0006171=PMID:10899090, GO:0007626=GO_REF:0000019, GO:0043154=GO_REF:0000019, GO:0048011=Reactome:REACT_11061, GO:0006355=GO_REF:0000019, GO:0042493=GO_REF:0000019, GO:0035249=GO_REF:0000019, GO:0051881=GO_REF:0000019, GO:0006915=PMID:7818494, GO:0012505=GO_REF:0000019, GO:0006968=PMID:10051547, GO:0001975=GO_REF:0000019, GO:0031802=GO_REF:0000019, GO:0016020=PMID:10051547, GO:0007596=PMID:10899090, GO:0048812=GO_REF:0000019, GO:0050728=GO_REF:0000019, GO:0044446=PMID:16339847, GO:0042755=GO_REF:0000019, GO:0016021=GO_REF:0000038, GO:0006469=GO_REF:0000019, GO:0007169=Reactome:REACT_11064, GO:0007600=PMID:9262401, GO:0043116=GO_REF:0000019} P29274 Adenosine receptor A2a protein 20130415 {GO:0006909=TAS, GO:0005515=IPI, GO:0046636=IEA, GO:0008015=TAS, GO:0043524=IEA, GO:0048167=IEA, GO:0045211=IEA, GO:0043025=IEA, GO:0051924=IEA, GO:0030673=IEA, GO:0014061=IEA, GO:0048786=IEA, GO:0046982=IEA, GO:0060134=IEA, GO:0051968=IEA, GO:0060079=IEA, GO:0014069=IEA, GO:0007417=TAS, GO:0032230=IEA, GO:0007271=IEA, GO:0001609=IEA, GO:0042734=IEA, GO:0060080=IEA, GO:0005887=TAS, GO:0051393=IEA, GO:0035815=IEA, GO:0007188=TAS, GO:0007189=IEA, GO:0019899=IPI, GO:0035810=IEA, GO:0008285=IEA, GO:0005886=TAS, GO:2001235=IEA, GO:0030819=IEA, GO:0007267=TAS, GO:0050714=IEA, GO:0014057=IEA, GO:0048143=IEA, GO:0007205=IEA, GO:0032279=IEA, GO:0014049=IEA, GO:0007190=TAS, GO:0006954=TAS, GO:0031000=IEA, GO:0040013=IEA, GO:0042311=IEA, GO:0001963=IEA, GO:0006171=TAS, GO:0007626=IEA, GO:0043154=IEA, GO:0048011=TAS, GO:0006355=IEA, GO:0042493=IEA, GO:0035249=IEA, GO:0051881=IEA, GO:0006915=TAS, GO:0012505=IEA, GO:0006968=TAS, GO:0001975=IEA, GO:0031802=IEA, GO:0016020=TAS, GO:0007596=TAS, GO:0048812=IEA, GO:0050728=IEA, GO:0044446=IDA, GO:0042755=IEA, GO:0016021=IEA, GO:0006469=IEA, GO:0007169=TAS, GO:0007600=TAS, GO:0043116=IEA} activation of adenylate cyclase activity, adenylate cyclase-activating G-protein coupled receptor signaling pathway, adenylate cyclase-modulating G-protein coupled receptor signaling pathway, apoptotic process, astrocyte activation, blood circulation, blood coagulation, cAMP biosynthetic process, cell-cell signaling, cellular defense response, central nervous system development, eating behavior, inflammatory response, locomotory behavior, negative regulation of alpha-beta T cell activation, negative regulation of cell proliferation, negative regulation of cysteine-type endopeptidase activity involved in apoptotic process, negative regulation of inflammatory response, negative regulation of locomotion, negative regulation of neuron apoptotic process, negative regulation of protein kinase activity, negative regulation of vascular permeability, neuron projection morphogenesis, neurotrophin TRK receptor signaling pathway, phagocytosis, positive regulation of acetylcholine secretion, positive regulation of apoptotic signaling pathway, positive regulation of cAMP biosynthetic process, positive regulation of glutamate secretion, positive regulation of protein secretion, positive regulation of renal sodium excretion, positive regulation of synaptic transmission, GABAergic, positive regulation of synaptic transmission, glutamatergic, positive regulation of urine volume, prepulse inhibition, protein kinase C-activating G-protein coupled receptor signaling pathway, regulation of calcium ion transport, regulation of excitatory postsynaptic membrane potential, regulation of inhibitory postsynaptic membrane potential, regulation of mitochondrial membrane potential, regulation of norepinephrine secretion, regulation of synaptic plasticity, regulation of transcription, DNA-dependent, response to amphetamine, response to caffeine, response to drug, sensory perception, synaptic transmission, cholinergic, synaptic transmission, dopaminergic, synaptic transmission, glutamatergic, transmembrane receptor protein tyrosine kinase signaling pathway, vasodilation asymmetric synapse, axolemma, endomembrane system, integral to membrane, integral to plasma membrane, intracellular organelle part, membrane, neuronal cell body, plasma membrane, postsynaptic density, postsynaptic membrane, presynaptic active zone, presynaptic membrane G-protein coupled adenosine receptor activity, alpha-actinin binding, enzyme binding, protein binding, protein heterodimerization activity, type 5 metabotropic glutamate receptor binding Human UniProtKB:P14416 ADORA2B Reactome UniProtKB {GO:0032755=GO_REF:0000019, GO:0007588=PMID:7836474, GO:0005886=Reactome:REACT_22268, GO:0007254=PMID:10101031, GO:0032722=GO_REF:0000019, GO:0010575=GO_REF:0000019, GO:0043306=GO_REF:0000019, GO:0060087=GO_REF:0000019, GO:0007190=PMID:8022409, GO:0001609=GO_REF:0000002, GO:0000187=PMID:10101031, GO:0006968=PMID:10101031, GO:0007186=PMID:7558011, GO:0005887=PMID:7558011, GO:0031668=GO_REF:0000019, GO:0030828=GO_REF:0000019, GO:0031284=GO_REF:0000019, GO:0007189=GO_REF:0000019, GO:0002882=GO_REF:0000019} P29275 Adenosine receptor A2b protein 20090427 {GO:0032755=IEA, GO:0007588=TAS, GO:0005886=TAS, GO:0007254=TAS, GO:0032722=IEA, GO:0010575=IEA, GO:0043306=IEA, GO:0060087=IEA, GO:0007190=TAS, GO:0001609=IEA, GO:0000187=TAS, GO:0006968=TAS, GO:0007186=TAS, GO:0005887=TAS, GO:0031668=IEA, GO:0030828=IEA, GO:0031284=IEA, GO:0007189=IEA, GO:0002882=IEA} G-protein coupled receptor signaling pathway, JNK cascade, activation of MAPK activity, activation of adenylate cyclase activity, adenylate cyclase-activating G-protein coupled receptor signaling pathway, cellular defense response, cellular response to extracellular stimulus, excretion, positive regulation of cGMP biosynthetic process, positive regulation of chemokine production, positive regulation of chronic inflammatory response to non-antigenic stimulus, positive regulation of guanylate cyclase activity, positive regulation of interleukin-6 production, positive regulation of mast cell degranulation, positive regulation vascular endothelial growth factor production, relaxation of vascular smooth muscle integral to plasma membrane, plasma membrane G-protein coupled adenosine receptor activity Human ADORA3 UniProtKB UniProtKB {GO:0005886=GO_REF:0000039, GO:0008016=PMID:9837869, GO:0009611=PMID:9837869, GO:0014068=GO_REF:0000019, GO:0043306=GO_REF:0000019, GO:0050850=GO_REF:0000019, GO:0070257=GO_REF:0000019, GO:0001609=GO_REF:0000019, GO:0007165=PMID:9380026, GO:0007190=PMID:9380026, GO:0006954=PMID:9164961, GO:0002553=GO_REF:0000019, GO:0005887=GO_REF:0000019, GO:0002687=GO_REF:0000019, GO:0050729=GO_REF:0000019, GO:0016021=GO_REF:0000037} Q6P2N6 Protein ADORA3, isoform 3 protein 20130413 {GO:0005886=IEA, GO:0008016=TAS, GO:0009611=TAS, GO:0014068=IEA, GO:0043306=IEA, GO:0050850=IEA, GO:0070257=IEA, GO:0001609=IEA, GO:0007165=TAS, GO:0007190=TAS, GO:0006954=TAS, GO:0002553=IEA, GO:0005887=IEA, GO:0002687=IEA, GO:0050729=IEA, GO:0016021=IEA} activation of adenylate cyclase activity, histamine secretion by mast cell, inflammatory response, positive regulation of calcium-mediated signaling, positive regulation of inflammatory response, positive regulation of leukocyte migration, positive regulation of mast cell degranulation, positive regulation of mucus secretion, positive regulation of phosphatidylinositol 3-kinase cascade, regulation of heart contraction, response to wounding, signal transduction integral to membrane, integral to plasma membrane, plasma membrane G-protein coupled adenosine receptor activity Human UniProtKB-SubCell:SL-0039 ADPGK UniPathway UniProtKB {GO:0043843=GO_REF:0000003, GO:0016301=GO_REF:0000038, GO:0005975=GO_REF:0000002, GO:0016773=GO_REF:0000002, GO:0005576=GO_REF:0000039, GO:0006096=GO_REF:0000041, GO:0046872=GO_REF:0000037} Q9BRR6 ADP-dependent glucokinase protein 20130413 {GO:0043843=IEA, GO:0016301=IEA, GO:0005975=IEA, GO:0016773=IEA, GO:0005576=IEA, GO:0006096=IEA, GO:0046872=IEA} carbohydrate metabolic process, glycolysis extracellular region ADP-specific glucokinase activity, kinase activity, metal ion binding, phosphotransferase activity, alcohol group as acceptor Human UniPathway:UPA00109 ADPRH UniProtKB UniProtKB {GO:0000287=GO_REF:0000002, GO:0003875=PMID:8349667, GO:0051725=GO_REF:0000002, GO:0006464=PMID:8349667} P54922 Protein ADP-ribosylarginine hydrolase protein 20080311 {GO:0000287=IEA, GO:0003875=IMP, GO:0051725=IEA, GO:0006464=IMP} cellular protein modification process, protein de-ADP-ribosylation ADP-ribosylarginine hydrolase activity, magnesium ion binding Human ADPRHL2 HPA UniProtKB {GO:0005759=GO_REF:0000039, GO:0005730=GO_REF:0000052, GO:0004649=GO_REF:0000003, GO:0005634=GO_REF:0000052, GO:0046872=GO_REF:0000037} Q9NX46 Poly(ADP-ribose) glycohydrolase ARH3 protein 20101115 {GO:0005759=IEA, GO:0005730=IDA, GO:0004649=IEA, GO:0005634=IDA, GO:0046872=IEA} mitochondrial matrix, nucleolus, nucleus metal ion binding, poly(ADP-ribose) glycohydrolase activity NOT Human ADRA1A BHF-UCL UniProtKB {GO:0030018=GO_REF:0000019, GO:0060402=GO_REF:0000024, GO:0008285=PMID:10860850, GO:0005886=Reactome:REACT_22436, GO:0035024=GO_REF:0000024, GO:0007267=PMID:8396931, GO:0007200=GO_REF:0000019, GO:0005634=PMID:22120526, GO:0007202=GO_REF:0000024, GO:0007204=GO_REF:0000024, GO:0007243=PMID:10671514, GO:0007512=GO_REF:0000019, GO:0006939=PMID:8183249, GO:0003084=GO_REF:0000019, GO:0001985=GO_REF:0000019, GO:0045907=GO_REF:0000024, GO:0090037=GO_REF:0000024, GO:0060452=GO_REF:0000024, GO:0035265=GO_REF:0000019, GO:0045987=GO_REF:0000019, GO:0045760=GO_REF:0000024, GO:0009725=GO_REF:0000024, GO:0070374=GO_REF:0000024, GO:0031965=PMID:22120526, GO:0004937=GO_REF:0000024, GO:0046982=PMID:22120526, GO:0042493=GO_REF:0000024, GO:0007568=GO_REF:0000024, GO:0006950=GO_REF:0000024, GO:0097195=GO_REF:0000019, GO:0030315=GO_REF:0000019, GO:0006915=PMID:10671514, GO:0060073=GO_REF:0000019, GO:0001996=GO_REF:0000019, GO:0007165=PMID:8396931, GO:0001994=GO_REF:0000019, GO:0007186=PMID:10860850, GO:0005887=PMID:8396931, GO:0001997=GO_REF:0000019, GO:0032229=GO_REF:0000024, GO:0016049=GO_REF:0000019, GO:0016021=GO_REF:0000038, GO:0043410=PMID:22120526} P35348 Alpha-1A adrenergic receptor protein 20100202 {GO:0030018=IEA, GO:0060402=ISS, GO:0008285=TAS, GO:0005886=TAS, GO:0035024=ISS, GO:0007267=TAS, GO:0007200=IEA, GO:0005634=IDA, GO:0007202=ISS, GO:0007204=ISS, GO:0007243=TAS, GO:0007512=IEA, GO:0006939=TAS, GO:0003084=IEA, GO:0001985=IEA, GO:0045907=ISS, GO:0090037=ISS, GO:0060452=ISS, GO:0035265=IEA, GO:0045987=IEA, GO:0045760=ISS, GO:0009725=ISS, GO:0070374=ISS, GO:0031965=IDA, GO:0004937=ISS, GO:0046982=IDA, GO:0042493=ISS, GO:0007568=ISS, GO:0006950=ISS, GO:0097195=IEA, GO:0030315=IEA, GO:0006915=TAS, GO:0060073=IEA, GO:0001996=IEA, GO:0007165=TAS, GO:0001994=IEA, GO:0007186=TAS, GO:0005887=TAS, GO:0001997=IEA, GO:0032229=ISS, GO:0016049=IEA, GO:0016021=IEA, GO:0043410=IDA} G-protein coupled receptor signaling pathway, activation of phospholipase C activity, adult heart development, aging, apoptotic process, calcium ion transport into cytosol, cell growth, cell-cell signaling, elevation of cytosolic calcium ion concentration, intracellular protein kinase cascade, micturition, negative regulation of Rho protein signal transduction, negative regulation of cell proliferation, negative regulation of heart rate involved in baroreceptor response to increased systemic arterial blood pressure, negative regulation of synaptic transmission, GABAergic, norepinephrine-epinephrine vasoconstriction involved in regulation of systemic arterial blood pressure, organ growth, phospholipase C-activating G-protein coupled receptor signaling pathway, pilomotor reflex, positive regulation of ERK1 and ERK2 cascade, positive regulation of MAPK cascade, positive regulation of action potential, positive regulation of cardiac muscle contraction, positive regulation of heart rate by epinephrine-norepinephrine, positive regulation of protein kinase C signaling cascade, positive regulation of smooth muscle contraction, positive regulation of systemic arterial blood pressure, positive regulation of the force of heart contraction by epinephrine-norepinephrine, positive regulation of vasoconstriction, response to drug, response to hormone stimulus, response to stress, signal transduction, smooth muscle contraction T-tubule, Z disc, integral to membrane, integral to plasma membrane, nuclear membrane, nucleus, plasma membrane alpha1-adrenergic receptor activity, protein heterodimerization activity Human UniProtKB:P43140 ADRA1B Reactome UniProtKB {GO:0005886=Reactome:REACT_22436, GO:0008283=PMID:10820200, GO:0007267=PMID:1328250, GO:0048148=GO_REF:0000019, GO:0005634=PMID:22120526, GO:0007243=PMID:10820200, GO:0007512=GO_REF:0000019, GO:0001987=GO_REF:0000019, GO:0035265=GO_REF:0000019, GO:0007626=GO_REF:0000019, GO:0004937=GO_REF:0000019, GO:0031965=PMID:22120526, GO:0046982=PMID:22120526, GO:0043278=GO_REF:0000019, GO:0007275=PMID:10820200, GO:0042593=GO_REF:0000019, GO:0001996=GO_REF:0000019, GO:0001975=GO_REF:0000019, GO:0045818=GO_REF:0000019, GO:0045819=GO_REF:0000019, GO:0007186=PMID:2154750, GO:0005887=PMID:1328250, GO:0001974=GO_REF:0000019, GO:0008542=GO_REF:0000019, GO:0001997=GO_REF:0000019, GO:0016049=GO_REF:0000019, GO:0007188=PMID:10820200, GO:0043410=PMID:22120526} P35368 Alpha-1B adrenergic receptor protein 20090210 {GO:0005886=TAS, GO:0008283=TAS, GO:0007267=TAS, GO:0048148=IEA, GO:0005634=IDA, GO:0007243=TAS, GO:0007512=IEA, GO:0001987=IEA, GO:0035265=IEA, GO:0007626=IEA, GO:0004937=IEA, GO:0031965=IDA, GO:0046982=IDA, GO:0043278=IEA, GO:0007275=TAS, GO:0042593=IEA, GO:0001996=IEA, GO:0001975=IEA, GO:0045818=IEA, GO:0045819=IEA, GO:0007186=TAS, GO:0005887=TAS, GO:0001974=IEA, GO:0008542=IEA, GO:0001997=IEA, GO:0016049=IEA, GO:0007188=TAS, GO:0043410=IDA} G-protein coupled receptor signaling pathway, adenylate cyclase-modulating G-protein coupled receptor signaling pathway, adult heart development, behavioral response to cocaine, blood vessel remodeling, cell growth, cell proliferation, cell-cell signaling, glucose homeostasis, intracellular protein kinase cascade, locomotory behavior, multicellular organismal development, negative regulation of glycogen catabolic process, organ growth, positive regulation of MAPK cascade, positive regulation of glycogen catabolic process, positive regulation of heart rate by epinephrine-norepinephrine, positive regulation of the force of heart contraction by epinephrine-norepinephrine, response to amphetamine, response to morphine, vasoconstriction of artery involved in baroreceptor response to lowering of systemic arterial blood pressure, visual learning integral to plasma membrane, nuclear membrane, nucleus, plasma membrane alpha1-adrenergic receptor activity, protein heterodimerization activity Human ADRA1D Reactome UniProtKB {GO:0008284=PMID:10860850, GO:0004937=GO_REF:0000019, GO:0001994=GO_REF:0000019, GO:0005886=Reactome:REACT_22436, GO:0007186=PMID:1656955, GO:0001986=GO_REF:0000019, GO:0008283=PMID:10820200, GO:0005887=PMID:7746284, GO:0007267=PMID:1656955, GO:0007275=PMID:10820200, GO:0007188=PMID:10820200, GO:0006259=PMID:10969806} P25100 Alpha-1D adrenergic receptor protein 20090210 {GO:0008284=TAS, GO:0004937=IEA, GO:0001994=IEA, GO:0005886=TAS, GO:0007186=TAS, GO:0001986=IEA, GO:0008283=TAS, GO:0005887=TAS, GO:0007267=TAS, GO:0007275=TAS, GO:0007188=TAS, GO:0006259=TAS} DNA metabolic process, G-protein coupled receptor signaling pathway, adenylate cyclase-modulating G-protein coupled receptor signaling pathway, cell proliferation, cell-cell signaling, multicellular organismal development, negative regulation of the force of heart contraction involved in baroreceptor response to increased systemic arterial blood pressure, norepinephrine-epinephrine vasoconstriction involved in regulation of systemic arterial blood pressure, positive regulation of cell proliferation integral to plasma membrane, plasma membrane alpha1-adrenergic receptor activity Human ADRA2A BHF-UCL UniProtKB {GO:0005515=PMID:16531006, GO:0032811=PMID:16531006, GO:0045202=GO_REF:0000019, GO:0043268=PMID:1354394, GO:0001819=PMID:17655843, GO:0031696=PMID:16605244, GO:0042803=PMID:16605244, GO:0042596=GO_REF:0000019, GO:0070473=GO_REF:0000019, GO:0051926=GO_REF:0000024, GO:0046676=PMID:10952463, GO:0002526=GO_REF:0000019, GO:0007565=GO_REF:0000019, GO:0030335=PMID:17655843, GO:0046982=GO_REF:0000024, GO:0019901=PMID:15653687, GO:0045741=PMID:17655843, GO:0035625=PMID:17215105, GO:0030168=Reactome:REACT_798, GO:0010700=PMID:19477270, GO:0004938=PMID:10948191, GO:0043235=PMID:10948191, GO:0031692=GO_REF:0000024, GO:0007186=PMID:19965390, GO:0005887=PMID:10948191, GO:0071878=GO_REF:0000024, GO:0008284=PMID:10896916, GO:0051044=PMID:17655843, GO:0050995=PMID:10948198, GO:0030036=PMID:9624180, GO:0005886=Reactome:REACT_22380, GO:1901020=PMID:1354394, GO:0090303=PMID:17655843, GO:0030818=PMID:16531006, GO:0006928=PMID:9624180, GO:0031996=PMID:19477270, GO:0051379=PMID:10948191, GO:0007265=PMID:8226727, GO:0044281=Reactome:REACT_111217, GO:0007266=PMID:9624180, GO:0007194=PMID:1354394, GO:0032870=PMID:10948198, GO:0032147=PMID:15653687, GO:0051380=PMID:2823383, GO:0016323=PMID:17655843, GO:0005737=PMID:19477270, GO:0043406=PMID:19477270, GO:0045909=GO_REF:0000019, GO:0032148=PMID:17215105, GO:0071881=PMID:10948191, GO:0071882=PMID:10948191, GO:0071883=PMID:10948191, GO:0042593=PMID:10952463, GO:0006260=GO_REF:0000019, GO:0007165=PMID:2823383, GO:0050892=PMID:17655843, GO:0032795=PMID:10948191, GO:0006112=Reactome:REACT_1505, GO:0045955=PMID:19965390, GO:0050796=Reactome:REACT_18325, GO:0007596=Reactome:REACT_604, GO:0050955=GO_REF:0000019, GO:0061179=PMID:19965390} P08913 Alpha-2A adrenergic receptor protein 20120917 {GO:0005515=IPI, GO:0032811=NAS, GO:0045202=IEA, GO:0043268=ISS, GO:0001819=IDA, GO:0031696=IPI, GO:0042803=IDA, GO:0042596=IEA, GO:0070473=IEA, GO:0051926=ISS, GO:0046676=IMP, GO:0002526=IEA, GO:0007565=IEA, GO:0030335=IMP, GO:0046982=ISS, GO:0019901=IPI, GO:0045741=IDA, GO:0035625=IDA, GO:0030168=TAS, GO:0010700=TAS, GO:0004938=IDA, GO:0043235=IDA, GO:0031692=ISS, GO:0007186=ISS, GO:0005887=IDA, GO:0071878=ISS, GO:0008284=TAS, GO:0051044=IDA, GO:0050995=IGI, GO:0030036=TAS, GO:0005886=TAS, GO:1901020=ISS, GO:0090303=IMP, GO:0030818=IDA, GO:0006928=TAS, GO:0031996=IPI, GO:0051379=IDA, GO:0007265=TAS, GO:0044281=TAS, GO:0007266=TAS, GO:0007194=ISS, GO:0032870=IGI, GO:0032147=IDA, GO:0051380=IDA, GO:0016323=TAS, GO:0005737=IDA, GO:0043406=IDA, GO:0045909=IEA, GO:0032148=IDA, GO:0071881=IDA, GO:0071882=IDA, GO:0071883=IDA, GO:0042593=IMP, GO:0006260=IEA, GO:0007165=TAS, GO:0050892=TAS, GO:0032795=IDA, GO:0006112=TAS, GO:0045955=IC, GO:0050796=TAS, GO:0007596=TAS, GO:0050955=IEA, GO:0061179=IMP} DNA replication, G-protein coupled receptor signaling pathway, Ras protein signal transduction, Rho protein signal transduction, actin cytoskeleton organization, activation of MAPK activity by adrenergic receptor signaling pathway, activation of protein kinase B activity, activation of protein kinase activity, acute inflammatory response, adenylate cyclase-inhibiting adrenergic receptor signaling pathway, blood coagulation, cellular component movement, cellular response to hormone stimulus, energy reserve metabolic process, epidermal growth factor-activated receptor transactivation by G-protein coupled receptor signaling pathway, fear response, female pregnancy, glucose homeostasis, intestinal absorption, negative regulation of adenylate cyclase activity, negative regulation of adrenergic receptor signaling pathway, negative regulation of cAMP biosynthetic process, negative regulation of calcium ion transmembrane transporter activity, negative regulation of calcium ion transport, negative regulation of calcium ion-dependent exocytosis, negative regulation of epinephrine secretion, negative regulation of insulin secretion, negative regulation of insulin secretion involved in cellular response to glucose stimulus, negative regulation of lipid catabolic process, negative regulation of norepinephrine secretion, negative regulation of uterine smooth muscle contraction, phospholipase C-activating adrenergic receptor signaling pathway, platelet activation, positive regulation of MAP kinase activity, positive regulation of cell migration, positive regulation of cell proliferation, positive regulation of cytokine production, positive regulation of epidermal growth factor-activated receptor activity, positive regulation of membrane protein ectodomain proteolysis, positive regulation of potassium ion transport, positive regulation of vasodilation, positive regulation of wound healing, regulation of insulin secretion, signal transduction, small molecule metabolic process, thermoception basolateral plasma membrane, cytoplasm, integral to plasma membrane, plasma membrane, receptor complex, synapse alpha-1B adrenergic receptor binding, alpha-2C adrenergic receptor binding, alpha2-adrenergic receptor activity, epinephrine binding, heterotrimeric G-protein binding, norepinephrine binding, protein binding, protein heterodimerization activity, protein homodimerization activity, protein kinase binding, thioesterase binding Human UniProtKB:P18871 ADRA2B BHF-UCL UniProtKB {GO:0005515=PMID:16531006, GO:0007565=GO_REF:0000019, GO:0032811=PMID:16531006, GO:0005886=Reactome:REACT_22380, GO:0035625=PMID:17215105, GO:0007267=PMID:2164221, GO:0030168=Reactome:REACT_798, GO:0051379=PMID:17215105, GO:0001525=GO_REF:0000019, GO:0010700=PMID:19477270, GO:0045777=GO_REF:0000019, GO:0004938=PMID:17215105, GO:0070474=GO_REF:0000019, GO:0007186=PMID:2164221, GO:0007596=Reactome:REACT_604, GO:0005887=PMID:2164221, GO:0000165=GO_REF:0000019, GO:0045666=PMID:17215105, GO:0003056=GO_REF:0000019, GO:0032148=PMID:17215105, GO:0071883=PMID:17215105} P18089 Alpha-2B adrenergic receptor protein 20100624 {GO:0005515=IPI, GO:0007565=IEA, GO:0032811=NAS, GO:0005886=TAS, GO:0035625=IDA, GO:0007267=TAS, GO:0030168=TAS, GO:0051379=IDA, GO:0001525=IEA, GO:0010700=TAS, GO:0045777=IEA, GO:0004938=IDA, GO:0070474=IEA, GO:0007186=TAS, GO:0007596=TAS, GO:0005887=TAS, GO:0000165=IEA, GO:0045666=IDA, GO:0003056=IEA, GO:0032148=IDA, GO:0071883=IDA} G-protein coupled receptor signaling pathway, MAPK cascade, activation of MAPK activity by adrenergic receptor signaling pathway, activation of protein kinase B activity, angiogenesis, blood coagulation, cell-cell signaling, epidermal growth factor-activated receptor transactivation by G-protein coupled receptor signaling pathway, female pregnancy, negative regulation of epinephrine secretion, negative regulation of norepinephrine secretion, platelet activation, positive regulation of blood pressure, positive regulation of neuron differentiation, positive regulation of uterine smooth muscle contraction, regulation of vascular smooth muscle contraction integral to plasma membrane, plasma membrane alpha2-adrenergic receptor activity, epinephrine binding, protein binding Human ADRA2C BHF-UCL UniProtKB {GO:0005515=PMID:16531006, GO:0032811=PMID:16531006, GO:0005886=Reactome:REACT_22380, GO:0007267=PMID:9371698, GO:0051379=PMID:17215105, GO:0044281=Reactome:REACT_111217, GO:0031694=PMID:16605244, GO:0042803=PMID:16605244, GO:0005737=PMID:16605244, GO:0045907=GO_REF:0000019, GO:0070473=GO_REF:0000019, GO:0032148=PMID:17215105, GO:0043679=GO_REF:0000019, GO:0071883=PMID:17215105, GO:0007565=GO_REF:0000019, GO:0046982=PMID:16605244, GO:0035625=PMID:17215105, GO:0030168=Reactome:REACT_798, GO:0010700=PMID:19477270, GO:0004938=PMID:17215105, GO:0006112=Reactome:REACT_1505, GO:0050796=Reactome:REACT_18325, GO:0007186=PMID:9371698, GO:0045666=PMID:17215105, GO:0007596=Reactome:REACT_604, GO:0005887=PMID:16605244, GO:0016021=GO_REF:0000038, GO:0005768=PMID:10196213, GO:0051930=GO_REF:0000019} P18825 Alpha-2C adrenergic receptor protein 20100624 {GO:0005515=IPI, GO:0032811=NAS, GO:0005886=TAS, GO:0007267=TAS, GO:0051379=IDA, GO:0044281=TAS, GO:0031694=IPI, GO:0042803=IDA, GO:0005737=IDA, GO:0045907=IEA, GO:0070473=IEA, GO:0032148=IDA, GO:0043679=IEA, GO:0071883=IDA, GO:0007565=IEA, GO:0046982=IPI, GO:0035625=IDA, GO:0030168=TAS, GO:0010700=TAS, GO:0004938=IDA, GO:0006112=TAS, GO:0050796=TAS, GO:0007186=TAS, GO:0045666=IDA, GO:0007596=TAS, GO:0005887=IDA, GO:0016021=IEA, GO:0005768=TAS, GO:0051930=IEA} G-protein coupled receptor signaling pathway, activation of MAPK activity by adrenergic receptor signaling pathway, activation of protein kinase B activity, blood coagulation, cell-cell signaling, energy reserve metabolic process, epidermal growth factor-activated receptor transactivation by G-protein coupled receptor signaling pathway, female pregnancy, negative regulation of epinephrine secretion, negative regulation of norepinephrine secretion, negative regulation of uterine smooth muscle contraction, platelet activation, positive regulation of neuron differentiation, positive regulation of vasoconstriction, regulation of insulin secretion, regulation of sensory perception of pain, small molecule metabolic process axon terminus, cytoplasm, endosome, integral to membrane, integral to plasma membrane, plasma membrane alpha-2A adrenergic receptor binding, alpha2-adrenergic receptor activity, epinephrine binding, protein binding, protein heterodimerization activity, protein homodimerization activity Human ADRB1 BHF-UCL UniProtKB {GO:0005515=PMID:16316992, GO:0005886=Reactome:REACT_22268, GO:0030819=PMID:12529373, GO:0009409=GO_REF:0000019, GO:0002024=GO_REF:0000019, GO:0002025=GO_REF:0000019, GO:0051379=GO_REF:0000019, GO:0005634=GO_REF:0000019, GO:0007266=GO_REF:0000019, GO:2001259=GO_REF:0000019, GO:0031694=PMID:12529373, GO:0061051=GO_REF:0000019, GO:0007190=PMID:10212248, GO:0031649=GO_REF:0000019, GO:0051380=GO_REF:0000019, GO:0042596=GO_REF:0000019, GO:0003084=GO_REF:0000019, GO:0005737=GO_REF:0000019, GO:0040015=GO_REF:0000019, GO:0045986=GO_REF:0000019, GO:0008144=GO_REF:0000019, GO:0051924=GO_REF:0000019, GO:0007613=GO_REF:0000019, GO:0086004=GO_REF:0000019, GO:0003061=GO_REF:0000019, GO:0046982=PMID:12529373, GO:0033365=GO_REF:0000019, GO:0007568=GO_REF:0000019, GO:0055088=GO_REF:0000019, GO:0035240=GO_REF:0000019, GO:0006915=GO_REF:0000019, GO:0004939=PMID:8892658, GO:0030165=PMID:11526121, GO:0019233=GO_REF:0000019, GO:0001996=GO_REF:0000019, GO:0060080=GO_REF:0000019, GO:0046878=GO_REF:0000019, GO:0005887=PMID:10212248, GO:0050873=GO_REF:0000019, GO:0042060=GO_REF:0000019, GO:0035811=GO_REF:0000019, GO:0004940=GO_REF:0000019, GO:0007189=GO_REF:0000019, GO:0005980=GO_REF:0000019} P08588 Beta-1 adrenergic receptor protein 20100628 {GO:0005515=IPI, GO:0005886=TAS, GO:0030819=IDA, GO:0009409=IEA, GO:0002024=IEA, GO:0002025=IEA, GO:0051379=IEA, GO:0005634=IEA, GO:0007266=IEA, GO:2001259=IEA, GO:0031694=IPI, GO:0061051=IEA, GO:0007190=TAS, GO:0031649=IEA, GO:0051380=IEA, GO:0042596=IEA, GO:0003084=IEA, GO:0005737=IEA, GO:0040015=IEA, GO:0045986=IEA, GO:0008144=IEA, GO:0051924=IEA, GO:0007613=IEA, GO:0086004=IEA, GO:0003061=IEA, GO:0046982=IPI, GO:0033365=IEA, GO:0007568=IEA, GO:0055088=IEA, GO:0035240=IEA, GO:0006915=IEA, GO:0004939=TAS, GO:0030165=IPI, GO:0019233=IEA, GO:0001996=IEA, GO:0060080=IEA, GO:0046878=IEA, GO:0005887=TAS, GO:0050873=IEA, GO:0042060=IEA, GO:0035811=IEA, GO:0004940=IEA, GO:0007189=IEA, GO:0005980=IEA} Rho protein signal transduction, activation of adenylate cyclase activity, adenylate cyclase-activating G-protein coupled receptor signaling pathway, aging, apoptotic process, brown fat cell differentiation, diet induced thermogenesis, fear response, glycogen catabolic process, heat generation, lipid homeostasis, memory, negative regulation of multicellular organism growth, negative regulation of smooth muscle contraction, negative regulation of urine volume, positive regulation of cAMP biosynthetic process, positive regulation of cation channel activity, positive regulation of cell growth involved in cardiac muscle cell development, positive regulation of heart rate by epinephrine-norepinephrine, positive regulation of saliva secretion, positive regulation of systemic arterial blood pressure, positive regulation of the force of heart contraction by norepinephrine, protein localization to organelle, regulation of calcium ion transport, regulation of cardiac muscle cell contraction, regulation of inhibitory postsynaptic membrane potential, response to cold, sensory perception of pain, vasodilation by norepinephrine-epinephrine involved in regulation of systemic arterial blood pressure, wound healing cytoplasm, integral to plasma membrane, nucleus, plasma membrane PDZ domain binding, alpha-2A adrenergic receptor binding, beta-adrenergic receptor activity, beta1-adrenergic receptor activity, dopamine binding, drug binding, epinephrine binding, norepinephrine binding, protein binding, protein heterodimerization activity Human UniProtKB:P18871 ADRB2 BHF-UCL UniProtKB {GO:0005515=PMID:15123695, GO:0005886=Reactome:REACT_22268, GO:0045453=GO_REF:0000019, GO:0004941=PMID:15123695, GO:0009409=GO_REF:0000019, GO:0002024=GO_REF:0000019, GO:0015459=PMID:12297500, GO:0002025=GO_REF:0000019, GO:0005634=GO_REF:0000019, GO:0005764=PMID:9507004, GO:0042803=PMID:15123695, GO:0051380=PMID:15123695, GO:0031649=GO_REF:0000019, GO:0007190=PMID:15123695, GO:0016324=GO_REF:0000019, GO:0007171=PMID:10734107, GO:0040015=GO_REF:0000019, GO:0045986=GO_REF:0000019, GO:0045944=GO_REF:0000019, GO:0031398=PMID:19372219, GO:0030501=GO_REF:0000019, GO:0008179=GO_REF:0000019, GO:0008333=PMID:9507004, GO:0006898=PMID:15123695, GO:0002032=PMID:15123695, GO:0043235=PMID:15123695, GO:0005887=PMID:12297500, GO:0050873=GO_REF:0000019, GO:0002028=GO_REF:0000019, GO:0007188=PMID:2823249, GO:0007189=GO_REF:0000019, GO:0043410=PMID:15123695, GO:0007166=PMID:1371121, GO:0005768=PMID:10734107} P07550 Beta-2 adrenergic receptor protein 20120316 {GO:0005515=IPI, GO:0005886=TAS, GO:0045453=IEA, GO:0004941=IDA, GO:0009409=IEA, GO:0002024=IEA, GO:0015459=IDA, GO:0002025=IEA, GO:0005634=IEA, GO:0005764=TAS, GO:0042803=IDA, GO:0051380=IDA, GO:0031649=IEA, GO:0007190=IDA, GO:0016324=IEA, GO:0007171=TAS, GO:0040015=IEA, GO:0045986=IEA, GO:0045944=IEA, GO:0031398=IMP, GO:0030501=IEA, GO:0008179=IEA, GO:0008333=TAS, GO:0006898=IDA, GO:0002032=IDA, GO:0043235=IDA, GO:0005887=IDA, GO:0050873=IEA, GO:0002028=IEA, GO:0007188=TAS, GO:0007189=IEA, GO:0043410=IDA, GO:0007166=TAS, GO:0005768=TAS} activation of adenylate cyclase activity, activation of transmembrane receptor protein tyrosine kinase activity, adenylate cyclase-activating G-protein coupled receptor signaling pathway, adenylate cyclase-modulating G-protein coupled receptor signaling pathway, bone resorption, brown fat cell differentiation, cell surface receptor signaling pathway, desensitization of G-protein coupled receptor protein signaling pathway by arrestin, diet induced thermogenesis, endosome to lysosome transport, heat generation, negative regulation of multicellular organism growth, negative regulation of smooth muscle contraction, positive regulation of MAPK cascade, positive regulation of bone mineralization, positive regulation of protein ubiquitination, positive regulation of transcription from RNA polymerase II promoter, receptor-mediated endocytosis, regulation of sodium ion transport, response to cold, vasodilation by norepinephrine-epinephrine involved in regulation of systemic arterial blood pressure apical plasma membrane, endosome, integral to plasma membrane, lysosome, nucleus, plasma membrane, receptor complex adenylate cyclase binding, beta2-adrenergic receptor activity, norepinephrine binding, potassium channel regulator activity, protein binding, protein homodimerization activity Human ADRB3 Reactome UniProtKB {GO:0005515=PMID:15123695, GO:0005886=Reactome:REACT_22268, GO:0009409=GO_REF:0000019, GO:0002024=GO_REF:0000019, GO:0031699=GO_REF:0000019, GO:0002025=GO_REF:0000019, GO:0051379=GO_REF:0000019, GO:0005634=GO_REF:0000019, GO:0006091=PMID:2570461, GO:0015052=PMID:9892244, GO:0042803=PMID:15123695, GO:0051380=PMID:15123695, GO:0031649=GO_REF:0000019, GO:0007190=PMID:15123695, GO:0040015=GO_REF:0000019, GO:0046677=GO_REF:0000019, GO:0005975=PMID:2570461, GO:0007568=GO_REF:0000019, GO:0004939=PMID:15123695, GO:0006898=PMID:15123695, GO:0002032=PMID:15123695, GO:0043235=PMID:15123695, GO:0006112=PMID:1718744, GO:0005887=PMID:1718744, GO:0007187=PMID:2570461, GO:0050873=GO_REF:0000019, GO:0042755=GO_REF:0000019, GO:0007188=PMID:1718744, GO:0007189=GO_REF:0000019, GO:0043410=PMID:15123695} P13945 Beta-3 adrenergic receptor protein 20090210 {GO:0005515=IPI, GO:0005886=TAS, GO:0009409=IEA, GO:0002024=IEA, GO:0031699=IEA, GO:0002025=IEA, GO:0051379=IEA, GO:0005634=IEA, GO:0006091=TAS, GO:0015052=IMP, GO:0042803=IDA, GO:0051380=IDA, GO:0031649=IEA, GO:0007190=IDA, GO:0040015=IEA, GO:0046677=IEA, GO:0005975=TAS, GO:0007568=IEA, GO:0004939=IDA, GO:0006898=IDA, GO:0002032=IDA, GO:0043235=IDA, GO:0006112=TAS, GO:0005887=TAS, GO:0007187=TAS, GO:0050873=IEA, GO:0042755=IEA, GO:0007188=TAS, GO:0007189=IEA, GO:0043410=IDA} G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger, activation of adenylate cyclase activity, adenylate cyclase-activating G-protein coupled receptor signaling pathway, adenylate cyclase-modulating G-protein coupled receptor signaling pathway, aging, brown fat cell differentiation, carbohydrate metabolic process, desensitization of G-protein coupled receptor protein signaling pathway by arrestin, diet induced thermogenesis, eating behavior, energy reserve metabolic process, generation of precursor metabolites and energy, heat generation, negative regulation of multicellular organism growth, positive regulation of MAPK cascade, receptor-mediated endocytosis, response to antibiotic, response to cold, vasodilation by norepinephrine-epinephrine involved in regulation of systemic arterial blood pressure integral to plasma membrane, nucleus, plasma membrane, receptor complex beta-3 adrenergic receptor binding, beta-adrenergic receptor activity, beta3-adrenergic receptor activity, epinephrine binding, norepinephrine binding, protein binding, protein homodimerization activity Human ADRBK1 BHF-UCL UniProtKB {GO:0005515=PMID:17986524, GO:0005886=Reactome:REACT_19213, GO:0038032=GO_REF:0000002, GO:0007202=Reactome:REACT_12079, GO:0060048=PMID:15051637, GO:0031694=GO_REF:0000024, GO:0005829=Reactome:REACT_15534, GO:0031623=PMID:20074556, GO:0007507=GO_REF:0000019, GO:0005737=PMID:17986524, GO:0005543=GO_REF:0000002, GO:0004703=GO_REF:0000024, GO:0007173=Reactome:REACT_9417, GO:0018105=GO_REF:0000024, GO:0018107=GO_REF:0000019, GO:0045988=PMID:15051637, GO:0048011=Reactome:REACT_11061, GO:0003108=PMID:15051637, GO:0007217=PMID:17986524, GO:0007213=GO_REF:0000024, GO:0005524=GO_REF:0000037, GO:0033605=GO_REF:0000024, GO:0007165=Reactome:REACT_12478, GO:0004672=GO_REF:0000024, GO:0016020=GO_REF:0000024, GO:0008543=Reactome:REACT_9470, GO:0045087=Reactome:REACT_6802, GO:0002029=GO_REF:0000024, GO:0047696=GO_REF:0000003, GO:0031755=PMID:19306925} P25098 Beta-adrenergic receptor kinase 1 protein 20080208 {GO:0005515=IPI, GO:0005886=TAS, GO:0038032=IEA, GO:0007202=TAS, GO:0060048=IMP, GO:0031694=ISS, GO:0005829=TAS, GO:0031623=IDA, GO:0007507=IEA, GO:0005737=IDA, GO:0005543=IEA, GO:0004703=ISS, GO:0007173=TAS, GO:0018105=ISS, GO:0018107=IEA, GO:0045988=IMP, GO:0048011=TAS, GO:0003108=IMP, GO:0007217=IDA, GO:0007213=ISS, GO:0005524=IEA, GO:0033605=ISS, GO:0007165=TAS, GO:0004672=ISS, GO:0016020=ISS, GO:0008543=TAS, GO:0045087=TAS, GO:0002029=ISS, GO:0047696=IEA, GO:0031755=IDA} G-protein coupled acetylcholine receptor signaling pathway, activation of phospholipase C activity, cardiac muscle contraction, desensitization of G-protein coupled receptor protein signaling pathway, epidermal growth factor receptor signaling pathway, fibroblast growth factor receptor signaling pathway, heart development, innate immune response, negative regulation of striated muscle contraction, negative regulation of the force of heart contraction by chemical signal, neurotrophin TRK receptor signaling pathway, peptidyl-serine phosphorylation, peptidyl-threonine phosphorylation, positive regulation of catecholamine secretion, receptor internalization, signal transduction, tachykinin receptor signaling pathway, termination of G-protein coupled receptor signaling pathway cytoplasm, cytosol, membrane, plasma membrane ATP binding, Edg-2 lysophosphatidic acid receptor binding, G-protein coupled receptor kinase activity, alpha-2A adrenergic receptor binding, beta-adrenergic receptor kinase activity, phospholipid binding, protein binding, protein kinase activity Human UniProtKB:P26817 ADRBK2 PINC UniProtKB {GO:0031623=PMID:20074556, GO:0007165=GO_REF:0000002, GO:0004672=PMID:8427589, GO:0004703=GO_REF:0000019, GO:0005543=GO_REF:0000002, GO:0047696=GO_REF:0000003, GO:0038032=GO_REF:0000002, GO:0005524=GO_REF:0000037} P35626 Beta-adrenergic receptor kinase 2 protein 20030904 {GO:0031623=IDA, GO:0007165=IEA, GO:0004672=TAS, GO:0004703=IEA, GO:0005543=IEA, GO:0047696=IEA, GO:0038032=IEA, GO:0005524=IEA} receptor internalization, signal transduction, termination of G-protein coupled receptor signaling pathway ATP binding, G-protein coupled receptor kinase activity, beta-adrenergic receptor kinase activity, phospholipid binding, protein kinase activity Human ADRM1 GOC UniProtKB {GO:0000502=PMID:16990800, GO:0006368=PMID:11818576, GO:0005886=GO_REF:0000052, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0002020=PMID:18922472, GO:0043248=PMID:16990800, GO:0005737=GO_REF:0000052, GO:0016020=PMID:8033103, GO:0005887=PMID:8033103, GO:0061133=PMID:16990800, GO:0010950=PMID:16990800, GO:0070628=PMID:18162577} Q16186 Proteasomal ubiquitin receptor ADRM1 protein 20130413 {GO:0000502=IDA, GO:0006368=IMP, GO:0005886=IDA, GO:0005730=IDA, GO:0005634=IDA, GO:0002020=IPI, GO:0043248=IDA, GO:0005737=IDA, GO:0016020=TAS, GO:0005887=TAS, GO:0061133=IDA, GO:0010950=IDA, GO:0070628=IDA} positive regulation of endopeptidase activity, proteasome assembly, transcription elongation from RNA polymerase II promoter cytoplasm, integral to plasma membrane, membrane, nucleolus, nucleus, plasma membrane, proteasome complex endopeptidase activator activity, protease binding, proteasome binding Human ADSL HPA UniProtKB {GO:0001666=GO_REF:0000019, GO:0009168=Reactome:REACT_1776, GO:0051262=PMID:16973378, GO:0007584=GO_REF:0000019, GO:0014850=GO_REF:0000019, GO:0070626=GO_REF:0000003, GO:0055086=Reactome:REACT_1698, GO:0004018=Reactome:REACT_1463, GO:0009152=GO_REF:0000002, GO:0044281=Reactome:REACT_111217, GO:0044208=GO_REF:0000041, GO:0005829=Reactome:REACT_1463, GO:0005739=GO_REF:0000019, GO:0009060=GO_REF:0000019, GO:0005737=GO_REF:0000052, GO:0006167=PMID:11428554, GO:0042594=GO_REF:0000019, GO:0006144=Reactome:REACT_522, GO:0006164=PMID:10888601, GO:0006189=GO_REF:0000041} P30566 Adenylosuccinate lyase protein 20080205 {GO:0001666=IEA, GO:0009168=TAS, GO:0051262=IDA, GO:0007584=IEA, GO:0014850=IEA, GO:0070626=IEA, GO:0055086=TAS, GO:0004018=TAS, GO:0009152=IEA, GO:0044281=TAS, GO:0044208=IEA, GO:0005829=TAS, GO:0005739=IEA, GO:0009060=IEA, GO:0005737=IDA, GO:0006167=IDA, GO:0042594=IEA, GO:0006144=TAS, GO:0006164=IC, GO:0006189=IEA} 'de novo' AMP biosynthetic process, 'de novo' IMP biosynthetic process, AMP biosynthetic process, aerobic respiration, nucleobase-containing small molecule metabolic process, protein tetramerization, purine nucleobase metabolic process, purine nucleotide biosynthetic process, purine ribonucleoside monophosphate biosynthetic process, purine ribonucleotide biosynthetic process, response to hypoxia, response to muscle activity, response to nutrient, response to starvation, small molecule metabolic process cytoplasm, cytosol, mitochondrion (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido)succinate AMP-lyase (fumarate-forming) activity, N6-(1,2-dicarboxyethyl)AMP AMP-lyase (fumarate-forming) activity Human ADSS HPA UniProtKB {GO:0046040=GO_REF:0000019, GO:0009168=Reactome:REACT_1776, GO:0000287=GO_REF:0000020, GO:0006531=GO_REF:0000019, GO:0005886=GO_REF:0000052, GO:0004019=PMID:1592113, GO:0055086=Reactome:REACT_1698, GO:0044281=Reactome:REACT_111217, GO:0044208=GO_REF:0000041, GO:0005525=PMID:1592113, GO:0014074=GO_REF:0000019, GO:0005829=Reactome:REACT_1719, GO:0006184=GO_REF:0000019, GO:0005737=GO_REF:0000052, GO:0071257=GO_REF:0000019, GO:0006167=PMID:1592113, GO:0006144=Reactome:REACT_522, GO:0042301=PMID:1592113, GO:0060359=GO_REF:0000019, GO:0002376=PMID:15786719} P30520 Adenylosuccinate synthetase isozyme 2 protein 20101115 {GO:0046040=IEA, GO:0009168=TAS, GO:0000287=IEA, GO:0006531=IEA, GO:0005886=IDA, GO:0004019=NAS, GO:0055086=TAS, GO:0044281=TAS, GO:0044208=IEA, GO:0005525=NAS, GO:0014074=IEA, GO:0005829=TAS, GO:0006184=IEA, GO:0005737=IDA, GO:0071257=IEA, GO:0006167=NAS, GO:0006144=TAS, GO:0042301=NAS, GO:0060359=IEA, GO:0002376=NAS} 'de novo' AMP biosynthetic process, AMP biosynthetic process, GTP catabolic process, IMP metabolic process, aspartate metabolic process, cellular response to electrical stimulus, immune system process, nucleobase-containing small molecule metabolic process, purine nucleobase metabolic process, purine ribonucleoside monophosphate biosynthetic process, response to ammonium ion, response to purine-containing compound, small molecule metabolic process cytoplasm, cytosol, plasma membrane GTP binding, adenylosuccinate synthase activity, magnesium ion binding, phosphate ion binding Human ADSSL1 Reactome UniProtKB {GO:0000287=GO_REF:0000020, GO:0009168=Reactome:REACT_1776, GO:0004019=PMID:15786719, GO:0055086=Reactome:REACT_1698, GO:0044208=GO_REF:0000041, GO:0044281=Reactome:REACT_111217, GO:0005525=PMID:15786719, GO:0005829=Reactome:REACT_1719, GO:0005737=PMID:15786719, GO:0006167=PMID:15786719, GO:0006144=Reactome:REACT_522, GO:0042301=PMID:15786719, GO:0006164=GO_REF:0000002, GO:0002376=PMID:15786719} Q8N142 Adenylosuccinate synthetase isozyme 1 protein 20130213 {GO:0000287=IEA, GO:0009168=TAS, GO:0004019=IDA, GO:0055086=TAS, GO:0044208=IEA, GO:0044281=TAS, GO:0005525=NAS, GO:0005829=TAS, GO:0005737=IDA, GO:0006167=IDA, GO:0006144=TAS, GO:0042301=NAS, GO:0006164=IEA, GO:0002376=NAS} 'de novo' AMP biosynthetic process, AMP biosynthetic process, immune system process, nucleobase-containing small molecule metabolic process, purine nucleobase metabolic process, purine nucleotide biosynthetic process, purine ribonucleoside monophosphate biosynthetic process, small molecule metabolic process cytoplasm, cytosol GTP binding, adenylosuccinate synthase activity, magnesium ion binding, phosphate ion binding Human AEBP1 PINC UniProtKB {GO:0005516=GO_REF:0000037, GO:0003700=PMID:8920928, GO:0003714=GO_REF:0000019, GO:0005634=GO_REF:0000039, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037, GO:0005737=GO_REF:0000039, GO:0001501=PMID:8920928, GO:0007517=PMID:9624159, GO:0006508=GO_REF:0000002, GO:0004180=PMID:8920928, GO:0008270=GO_REF:0000002, GO:0007155=GO_REF:0000002, GO:0004181=GO_REF:0000002} Q8IUX7 Adipocyte enhancer-binding protein 1 protein 20090721 {GO:0005516=IEA, GO:0003700=TAS, GO:0003714=IEA, GO:0005634=IEA, GO:0003677=IEA, GO:0006351=IEA, GO:0005737=IEA, GO:0001501=TAS, GO:0007517=TAS, GO:0006508=IEA, GO:0004180=TAS, GO:0008270=IEA, GO:0007155=IEA, GO:0004181=IEA} cell adhesion, muscle organ development, proteolysis, skeletal system development, transcription, DNA-dependent cytoplasm, nucleus DNA binding, calmodulin binding, carboxypeptidase activity, metallocarboxypeptidase activity, sequence-specific DNA binding transcription factor activity, transcription corepressor activity, zinc ion binding Human AEBP2 UniProtKB UniProtKB {GO:0006355=GO_REF:0000019, GO:0035098=PMID:20075857, GO:0003714=GO_REF:0000019, GO:0008270=GO_REF:0000002, GO:0003677=GO_REF:0000019, GO:0006351=GO_REF:0000037, GO:0016568=GO_REF:0000037} Q6ZN18 Zinc finger protein AEBP2 protein 20100127 {GO:0006355=IEA, GO:0035098=IDA, GO:0003714=IEA, GO:0008270=IEA, GO:0003677=IEA, GO:0006351=IEA, GO:0016568=IEA} chromatin modification, regulation of transcription, DNA-dependent, transcription, DNA-dependent ESC/E(Z) complex DNA binding, transcription corepressor activity, zinc ion binding Human AEN HPA UniProtKB {GO:0042771=PMID:18264133, GO:0004527=PMID:18264133, GO:0010212=PMID:16171785, GO:0005730=GO_REF:0000052, GO:0005654=PMID:16171785, GO:0005634=GO_REF:0000052, GO:0003676=GO_REF:0000002} Q8WTP8 Apoptosis-enhancing nuclease protein 20120912 {GO:0042771=IDA, GO:0004527=IDA, GO:0010212=IDA, GO:0005730=IDA, GO:0005654=IDA, GO:0005634=IDA, GO:0003676=IEA} intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator, response to ionizing radiation nucleolus, nucleoplasm, nucleus exonuclease activity, nucleic acid binding Human AES BHF-UCL UniProtKB {GO:0005515=PMID:22952044, GO:0032091=PMID:15489227, GO:0060761=PMID:15489227, GO:0003714=PMID:10660609, GO:0007275=PMID:8365415, GO:0000122=PMID:10660609, GO:0006351=GO_REF:0000037, GO:0001501=GO_REF:0000019, GO:0031668=GO_REF:0000019, GO:0009887=PMID:9809752, GO:0016055=GO_REF:0000037, GO:0045892=PMID:19460168, GO:0090090=PMID:19460168, GO:0070555=PMID:15489227, GO:0040008=GO_REF:0000019} Q08117 Amino-terminal enhancer of split protein 20090629 {GO:0005515=IPI, GO:0032091=IDA, GO:0060761=IMP, GO:0003714=IPI, GO:0007275=TAS, GO:0000122=IMP, GO:0006351=IEA, GO:0001501=IEA, GO:0031668=IEA, GO:0009887=TAS, GO:0016055=IEA, GO:0045892=IDA, GO:0090090=IDA, GO:0070555=IDA, GO:0040008=IEA} Wnt receptor signaling pathway, cellular response to extracellular stimulus, multicellular organismal development, negative regulation of canonical Wnt receptor signaling pathway, negative regulation of protein binding, negative regulation of response to cytokine stimulus, negative regulation of transcription from RNA polymerase II promoter, negative regulation of transcription, DNA-dependent, organ morphogenesis, regulation of growth, response to interleukin-1, skeletal system development, transcription, DNA-dependent protein binding, transcription corepressor activity Human AFAP1 HPA UniProtKB {GO:0005737=GO_REF:0000052, GO:0005543=GO_REF:0000002, GO:0003779=GO_REF:0000037, GO:0015629=GO_REF:0000052, GO:0005925=GO_REF:0000052} Q8N556 Actin filament-associated protein 1 protein 20101115 {GO:0005737=IDA, GO:0005543=IEA, GO:0003779=IEA, GO:0015629=IDA, GO:0005925=IDA} actin cytoskeleton, cytoplasm, focal adhesion actin binding, phospholipid binding Human AFAP1L1 UniProtKB UniProtKB {GO:0005737=GO_REF:0000039, GO:0030054=GO_REF:0000037, GO:0005543=GO_REF:0000002, GO:0071437=GO_REF:0000039, GO:0002102=GO_REF:0000039} Q8TED9 Actin filament-associated protein 1-like 1 protein 20130413 {GO:0005737=IEA, GO:0030054=IEA, GO:0005543=IEA, GO:0071437=IEA, GO:0002102=IEA} cell junction, cytoplasm, invadopodium, podosome phospholipid binding Human UniProtKB-SubCell:SL-0148 AFAP1L2 HPA UniProtKB {GO:0017124=PMID:17412687, GO:0005886=GO_REF:0000052, GO:0016235=GO_REF:0000052, GO:0045742=PMID:17412687, GO:0061098=PMID:17412687, GO:0005634=GO_REF:0000052, GO:0032757=PMID:17412687, GO:0007346=PMID:17412687, GO:0005737=GO_REF:0000052, GO:0005543=GO_REF:0000002, GO:0006954=PMID:17412687, GO:0030296=PMID:17412687, GO:0032675=PMID:17412687, GO:0045893=PMID:17412687, GO:0042169=PMID:17412687} Q8N4X5 Actin filament-associated protein 1-like 2 protein 20110516 {GO:0017124=IPI, GO:0005886=IDA, GO:0016235=IDA, GO:0045742=IDA, GO:0061098=IDA, GO:0005634=IDA, GO:0032757=IDA, GO:0007346=IDA, GO:0005737=IDA, GO:0005543=IEA, GO:0006954=IDA, GO:0030296=IDA, GO:0032675=IDA, GO:0045893=IDA, GO:0042169=IPI} inflammatory response, positive regulation of epidermal growth factor receptor signaling pathway, positive regulation of interleukin-8 production, positive regulation of protein tyrosine kinase activity, positive regulation of transcription, DNA-dependent, regulation of interleukin-6 production, regulation of mitotic cell cycle aggresome, cytoplasm, nucleus, plasma membrane SH2 domain binding, SH3 domain binding, phospholipid binding, protein tyrosine kinase activator activity Human AFF1 GOC UniProtKB {GO:0005515=PMID:22190034, GO:0006355=PMID:7689231, GO:0003700=PMID:7689231, GO:0005634=GO_REF:0000039, GO:0045893=GO_REF:0000019} P51825 AF4/FMR2 family member 1 protein 20130413 {GO:0005515=IPI, GO:0006355=TAS, GO:0003700=TAS, GO:0005634=IEA, GO:0045893=IEA} positive regulation of transcription, DNA-dependent, regulation of transcription, DNA-dependent nucleus protein binding, sequence-specific DNA binding transcription factor activity Human AFF2 PINC UniProtKB {GO:0008380=GO_REF:0000037, GO:0006397=GO_REF:0000037, GO:0016607=PMID:19136466, GO:0007420=PMID:8673086, GO:0002151=GO_REF:0000024, GO:0007611=GO_REF:0000019, GO:0043484=PMID:19136466} P51816 AF4/FMR2 family member 2 protein 20031120 {GO:0008380=IEA, GO:0006397=IEA, GO:0016607=IDA, GO:0007420=TAS, GO:0002151=ISS, GO:0007611=IEA, GO:0043484=IMP} RNA splicing, brain development, learning or memory, mRNA processing, regulation of RNA splicing nuclear speck G-quadruplex RNA binding Human AFF3 HPA UniProtKB {GO:0006355=GO_REF:0000037, GO:0003690=PMID:8555498, GO:0005730=GO_REF:0000052, GO:0035116=PMID:18616733, GO:0034612=PMID:20444755, GO:0005634=GO_REF:0000052, GO:0006351=GO_REF:0000037} P51826 AF4/FMR2 family member 3 protein 20111111 {GO:0006355=IEA, GO:0003690=IDA, GO:0005730=IDA, GO:0035116=IMP, GO:0034612=IMP, GO:0005634=IDA, GO:0006351=IEA} embryonic hindlimb morphogenesis, regulation of transcription, DNA-dependent, response to tumor necrosis factor, transcription, DNA-dependent nucleolus, nucleus double-stranded DNA binding Human AFF4 HPA UniProtKB {GO:0005739=GO_REF:0000052, GO:0005515=PMID:22190034, GO:0003700=PMID:10588740, GO:0006366=PMID:10588740, GO:0005730=GO_REF:0000052, GO:0007286=GO_REF:0000019, GO:0005634=GO_REF:0000052} Q9UHB7 AF4/FMR2 family member 4 protein 20101115 {GO:0005739=IDA, GO:0005515=IPI, GO:0003700=TAS, GO:0006366=TAS, GO:0005730=IDA, GO:0007286=IEA, GO:0005634=IDA} spermatid development, transcription from RNA polymerase II promoter mitochondrion, nucleolus, nucleus protein binding, sequence-specific DNA binding transcription factor activity Human AFG3L2 HPA UniProtKB {GO:0005515=PMID:14623864, GO:0008219=GO_REF:0000037, GO:0017111=GO_REF:0000002, GO:0034982=GO_REF:0000019, GO:0042552=GO_REF:0000019, GO:0005743=GO_REF:0000019, GO:0021675=GO_REF:0000019, GO:0007409=GO_REF:0000019, GO:0005524=GO_REF:0000037, GO:0005739=GO_REF:0000052, GO:0030163=GO_REF:0000002, GO:0008053=GO_REF:0000019, GO:0007528=GO_REF:0000019, GO:0040014=GO_REF:0000019, GO:0006508=GO_REF:0000037, GO:0008270=GO_REF:0000002, GO:0051082=PMID:10395799, GO:0016021=GO_REF:0000037, GO:0004222=GO_REF:0000002, GO:0042407=GO_REF:0000019, GO:0060013=GO_REF:0000019} Q9Y4W6 AFG3-like protein 2 protein 20101115 {GO:0005515=IPI, GO:0008219=IEA, GO:0017111=IEA, GO:0034982=IEA, GO:0042552=IEA, GO:0005743=IEA, GO:0021675=IEA, GO:0007409=IEA, GO:0005524=IEA, GO:0005739=IDA, GO:0030163=IEA, GO:0008053=IEA, GO:0007528=IEA, GO:0040014=IEA, GO:0006508=IEA, GO:0008270=IEA, GO:0051082=TAS, GO:0016021=IEA, GO:0004222=IEA, GO:0042407=IEA, GO:0060013=IEA} axonogenesis, cell death, cristae formation, mitochondrial fusion, mitochondrial protein processing, myelination, nerve development, neuromuscular junction development, protein catabolic process, proteolysis, regulation of multicellular organism growth, righting reflex integral to membrane, mitochondrial inner membrane, mitochondrion ATP binding, metalloendopeptidase activity, nucleoside-triphosphatase activity, protein binding, unfolded protein binding, zinc ion binding Human AFMID Reactome UniProtKB {GO:0034641=Reactome:REACT_13, GO:0006569=Reactome:REACT_916, GO:0019441=GO_REF:0000041, GO:0016787=GO_REF:0000002, GO:0004061=GO_REF:0000003, GO:0005634=GO_REF:0000039, GO:0044281=Reactome:REACT_111217, GO:0005829=GO_REF:0000039} Q63HM1 Kynurenine formamidase protein 20130301 {GO:0034641=TAS, GO:0006569=TAS, GO:0019441=IEA, GO:0016787=IEA, GO:0004061=IEA, GO:0005634=IEA, GO:0044281=TAS, GO:0005829=IEA} cellular nitrogen compound metabolic process, small molecule metabolic process, tryptophan catabolic process, tryptophan catabolic process to kynurenine cytosol, nucleus arylformamidase activity, hydrolase activity Human AFP ENSEMBL UniProtKB {GO:0005737=GO_REF:0000019, GO:0042448=GO_REF:0000019, GO:0006810=GO_REF:0000002, GO:0001542=GO_REF:0000019, GO:0060395=GO_REF:0000019, GO:0005615=GO_REF:0000019, GO:0046872=GO_REF:0000037} P02771 Alpha-fetoprotein protein 20130413 {GO:0005737=IEA, GO:0042448=IEA, GO:0006810=IEA, GO:0001542=IEA, GO:0060395=IEA, GO:0005615=IEA, GO:0046872=IEA} SMAD protein signal transduction, ovulation from ovarian follicle, progesterone metabolic process, transport cytoplasm, extracellular space metal ion binding Human Ensembl:ENSMUSP00000041006 AFTPH HPA UniProtKB {GO:0005737=GO_REF:0000052, GO:0005794=GO_REF:0000052, GO:0030121=PMID:15758025, GO:0030276=PMID:15758025, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0015031=GO_REF:0000037, GO:0043231=GO_REF:0000052, GO:0005829=PMID:15758025} Q6ULP2 Aftiphilin protein 20101115 {GO:0005737=IDA, GO:0005794=IDA, GO:0030121=IDA, GO:0030276=IDA, GO:0005730=IDA, GO:0005634=IDA, GO:0015031=IEA, GO:0043231=IDA, GO:0005829=IDA} protein transport AP-1 adaptor complex, Golgi apparatus, cytoplasm, cytosol, intracellular membrane-bounded organelle, nucleolus, nucleus clathrin binding Human AGA UniProtKB UniProtKB {GO:0051604=GO_REF:0000019, GO:0016787=GO_REF:0000002, GO:0005783=PMID:8776587, GO:0006517=PMID:1281977, GO:0006508=GO_REF:0000037, GO:0003948=PMID:1281977, GO:0008233=GO_REF:0000037, GO:0043621=GO_REF:0000019, GO:0005764=PMID:8776587} P20933 N(4)-(beta-N-acetylglucosaminyl)-L-asparaginase protein 20100514 {GO:0051604=IEA, GO:0016787=IEA, GO:0005783=IDA, GO:0006517=IDA, GO:0006508=IEA, GO:0003948=IDA, GO:0008233=IEA, GO:0043621=IEA, GO:0005764=IDA} protein deglycosylation, protein maturation, proteolysis endoplasmic reticulum, lysosome N4-(beta-N-acetylglucosaminyl)-L-asparaginase activity, hydrolase activity, peptidase activity, protein self-association Human AGAP1 UniProtKB UniProtKB {GO:0005622=GO_REF:0000002, GO:0008060=GO_REF:0000002, GO:0005737=GO_REF:0000039, GO:0005543=GO_REF:0000002, GO:0032312=GO_REF:0000002, GO:0007264=GO_REF:0000002, GO:0008270=GO_REF:0000002, GO:0015031=GO_REF:0000037, GO:0005525=GO_REF:0000037} Q9UPQ3 Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 1 protein 20130413 {GO:0005622=IEA, GO:0008060=IEA, GO:0005737=IEA, GO:0005543=IEA, GO:0032312=IEA, GO:0007264=IEA, GO:0008270=IEA, GO:0015031=IEA, GO:0005525=IEA} protein transport, regulation of ARF GTPase activity, small GTPase mediated signal transduction cytoplasm, intracellular ARF GTPase activator activity, GTP binding, phospholipid binding, zinc ion binding Human UniProtKB-SubCell:SL-0086 AGAP2 HPA UniProtKB {GO:0043066=GO_REF:0000019, GO:0019901=GO_REF:0000019, GO:0042177=PMID:18374643, GO:0007264=GO_REF:0000002, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0030295=GO_REF:0000019, GO:0015031=GO_REF:0000037, GO:0005525=GO_REF:0000037, GO:0046427=GO_REF:0000019, GO:0005622=GO_REF:0000002, GO:0005739=GO_REF:0000052, GO:0008060=GO_REF:0000002, GO:0043524=PMID:18374643, GO:0005543=GO_REF:0000002, GO:0007411=Reactome:REACT_18266, GO:0032312=GO_REF:0000002, GO:0045944=GO_REF:0000019, GO:2001240=GO_REF:0000019, GO:0008270=GO_REF:0000002, GO:0033601=GO_REF:0000019, GO:0060749=GO_REF:0000019} Q99490 Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 2 protein 20101115 {GO:0043066=IEA, GO:0019901=IEA, GO:0042177=IDA, GO:0007264=IEA, GO:0005730=IDA, GO:0005634=IDA, GO:0030295=IEA, GO:0015031=IEA, GO:0005525=IEA, GO:0046427=IEA, GO:0005622=IEA, GO:0005739=IDA, GO:0008060=IEA, GO:0043524=IGI, GO:0005543=IEA, GO:0007411=TAS, GO:0032312=IEA, GO:0045944=IEA, GO:2001240=IEA, GO:0008270=IEA, GO:0033601=IEA, GO:0060749=IEA} axon guidance, mammary gland alveolus development, negative regulation of apoptotic process, negative regulation of extrinsic apoptotic signaling pathway in absence of ligand, negative regulation of neuron apoptotic process, negative regulation of protein catabolic process, positive regulation of JAK-STAT cascade, positive regulation of mammary gland epithelial cell proliferation, positive regulation of transcription from RNA polymerase II promoter, protein transport, regulation of ARF GTPase activity, small GTPase mediated signal transduction intracellular, mitochondrion, nucleolus, nucleus ARF GTPase activator activity, GTP binding, phospholipid binding, protein kinase activator activity, protein kinase binding, zinc ion binding Human AGAP3 UniProtKB UniProtKB {GO:0007264=GO_REF:0000002, GO:0003924=GO_REF:0000019, GO:0005634=GO_REF:0000019, GO:0005525=GO_REF:0000037, GO:0071944=GO_REF:0000019, GO:0005622=GO_REF:0000002, GO:0008060=GO_REF:0000002, GO:0007165=GO_REF:0000002, GO:0005737=GO_REF:0000039, GO:0005543=GO_REF:0000002, GO:0016020=GO_REF:0000002, GO:0032312=GO_REF:0000002, GO:0034614=GO_REF:0000019, GO:0043161=GO_REF:0000019, GO:0008270=GO_REF:0000002, GO:0000060=GO_REF:0000019, GO:0031593=GO_REF:0000019} Q96P47 Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 3 protein 20130413 {GO:0007264=IEA, GO:0003924=IEA, GO:0005634=IEA, GO:0005525=IEA, GO:0071944=IEA, GO:0005622=IEA, GO:0008060=IEA, GO:0007165=IEA, GO:0005737=IEA, GO:0005543=IEA, GO:0016020=IEA, GO:0032312=IEA, GO:0034614=IEA, GO:0043161=IEA, GO:0008270=IEA, GO:0000060=IEA, GO:0031593=IEA} cellular response to reactive oxygen species, proteasomal ubiquitin-dependent protein catabolic process, protein import into nucleus, translocation, regulation of ARF GTPase activity, signal transduction, small GTPase mediated signal transduction cell periphery, cytoplasm, intracellular, membrane, nucleus ARF GTPase activator activity, GTP binding, GTPase activity, phospholipid binding, polyubiquitin binding, zinc ion binding Human UniProtKB-SubCell:SL-0086 AGAP4 InterPro UniProtKB {GO:0008060=GO_REF:0000002, GO:0005543=GO_REF:0000002, GO:0032312=GO_REF:0000002, GO:0008270=GO_REF:0000002} Q96P64 Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 4 protein 20130413 {GO:0008060=IEA, GO:0005543=IEA, GO:0032312=IEA, GO:0008270=IEA} regulation of ARF GTPase activity ARF GTPase activator activity, phospholipid binding, zinc ion binding Human InterPro:IPR001164 AGBL2 UniProtKB UniProtKB {GO:0006508=GO_REF:0000037, GO:0008270=GO_REF:0000002, GO:0004181=GO_REF:0000002, GO:0005829=GO_REF:0000024} Q5U5Z8 Cytosolic carboxypeptidase 2 protein 20101123 {GO:0006508=IEA, GO:0008270=IEA, GO:0004181=IEA, GO:0005829=ISS} proteolysis cytosol metallocarboxypeptidase activity, zinc ion binding Human UniProtKB:Q8CDK2 AGBL5 LIFEdb UniProtKB {GO:0005737=GO_REF:0000054, GO:0015631=GO_REF:0000024, GO:0035611=GO_REF:0000024, GO:0006508=GO_REF:0000037, GO:0008270=GO_REF:0000002, GO:0005634=GO_REF:0000024, GO:0035608=GO_REF:0000024, GO:0005829=GO_REF:0000024, GO:0004181=GO_REF:0000024} Q8NDL9 Cytosolic carboxypeptidase-like protein 5 protein 20100607 {GO:0005737=IDA, GO:0015631=ISS, GO:0035611=ISS, GO:0006508=IEA, GO:0008270=IEA, GO:0005634=ISS, GO:0035608=ISS, GO:0005829=ISS, GO:0004181=ISS} protein branching point deglutamylation, protein deglutamylation, proteolysis cytoplasm, cytosol, nucleus metallocarboxypeptidase activity, tubulin binding, zinc ion binding Human AGER UniProtKB UniProtKB {GO:0005515=PMID:21706016, GO:0005886=Reactome:REACT_25382, GO:0009611=PMID:10399917, GO:0005576=GO_REF:0000039, GO:0031175=PMID:10391939, GO:0050930=GO_REF:0000019, GO:0044548=PMID:15033494, GO:0006954=GO_REF:0000037, GO:0051092=PMID:10391939, GO:0016020=GO_REF:0000038, GO:0005887=PMID:1378843, GO:0045087=Reactome:REACT_6802, GO:0004872=PMID:8751438, GO:0007166=PMID:10835680, GO:0004888=PMID:1378843} Q5SSZ2 Advanced glycosylation end product-specific receptor protein 20130413 {GO:0005515=IPI, GO:0005886=TAS, GO:0009611=TAS, GO:0005576=IEA, GO:0031175=IGI, GO:0050930=IEA, GO:0044548=IPI, GO:0006954=IEA, GO:0051092=IDA, GO:0016020=IEA, GO:0005887=TAS, GO:0045087=TAS, GO:0004872=TAS, GO:0007166=TAS, GO:0004888=TAS} cell surface receptor signaling pathway, induction of positive chemotaxis, inflammatory response, innate immune response, neuron projection development, positive regulation of NF-kappaB transcription factor activity, response to wounding extracellular region, integral to plasma membrane, membrane, plasma membrane S100 protein binding, protein binding, receptor activity, transmembrane signaling receptor activity Human UniProtKB-KW:KW-0472 AGFG1 HPA UniProtKB {GO:0005515=PMID:18775314, GO:0005794=GO_REF:0000052, GO:0003723=PMID:7634337, GO:0007275=GO_REF:0000037, GO:0007283=GO_REF:0000037, GO:0003677=GO_REF:0000037, GO:0030154=GO_REF:0000037, GO:0043231=GO_REF:0000052, GO:0008060=GO_REF:0000002, GO:0006406=PMID:7634337, GO:0032312=GO_REF:0000002, GO:0005643=PMID:7637788, GO:0016023=GO_REF:0000039, GO:0008270=GO_REF:0000002} P52594 Arf-GAP domain and FG repeat-containing protein 1 protein 20081203 {GO:0005515=IPI, GO:0005794=IDA, GO:0003723=TAS, GO:0007275=IEA, GO:0007283=IEA, GO:0003677=IEA, GO:0030154=IEA, GO:0043231=IDA, GO:0008060=IEA, GO:0006406=TAS, GO:0032312=IEA, GO:0005643=TAS, GO:0016023=IEA, GO:0008270=IEA} cell differentiation, mRNA export from nucleus, multicellular organismal development, regulation of ARF GTPase activity, spermatogenesis Golgi apparatus, cytoplasmic membrane-bounded vesicle, intracellular membrane-bounded organelle, nuclear pore ARF GTPase activator activity, DNA binding, RNA binding, protein binding, zinc ion binding Human AGFG2 UniProtKB UniProtKB {GO:0008150=GO_REF:0000015, GO:0003674=GO_REF:0000015, GO:0008060=GO_REF:0000002, GO:0032312=GO_REF:0000002, GO:0008270=GO_REF:0000002, GO:0005575=GO_REF:0000015} O95081 Arf-GAP domain and FG repeat-containing protein 2 protein 20061026 {GO:0008150=ND, GO:0003674=ND, GO:0008060=IEA, GO:0032312=IEA, GO:0008270=IEA, GO:0005575=ND} biological_process, regulation of ARF GTPase activity cellular_component ARF GTPase activator activity, molecular_function, zinc ion binding Human AGGF1 UniProtKB UniProtKB {GO:0005515=PMID:14961121, GO:0006396=PMID:15486042, GO:0005737=PMID:14961121, GO:0048471=PMID:14961121, GO:0043499=PMID:14961121, GO:0001938=PMID:14961121, GO:0005576=PMID:14961121, GO:0001525=GO_REF:0000037, GO:0007155=PMID:14961121, GO:0003676=GO_REF:0000002, GO:0001570=PMID:15905966, GO:0045766=PMID:14961121} Q8N302 Angiogenic factor with G patch and FHA domains 1 protein 20051122 {GO:0005515=IPI, GO:0006396=TAS, GO:0005737=IDA, GO:0048471=IDA, GO:0043499=IDA, GO:0001938=IDA, GO:0005576=IDA, GO:0001525=IEA, GO:0007155=IDA, GO:0003676=IEA, GO:0001570=TAS, GO:0045766=IDA} RNA processing, angiogenesis, cell adhesion, positive regulation of angiogenesis, positive regulation of endothelial cell proliferation, vasculogenesis cytoplasm, extracellular region, perinuclear region of cytoplasm eukaryotic cell surface binding, nucleic acid binding, protein binding Human AGK UniPathway UniProtKB {GO:0031966=GO_REF:0000039, GO:0004143=GO_REF:0000003, GO:0047620=GO_REF:0000003, GO:0046486=GO_REF:0000041, GO:0046513=GO_REF:0000019, GO:0005524=GO_REF:0000037, GO:0001729=GO_REF:0000019, GO:0007205=GO_REF:0000002} Q53H12 Acylglycerol kinase, mitochondrial protein 20130413 {GO:0031966=IEA, GO:0004143=IEA, GO:0047620=IEA, GO:0046486=IEA, GO:0046513=IEA, GO:0005524=IEA, GO:0001729=IEA, GO:0007205=IEA} ceramide biosynthetic process, glycerolipid metabolic process, protein kinase C-activating G-protein coupled receptor signaling pathway mitochondrial membrane ATP binding, acylglycerol kinase activity, ceramide kinase activity, diacylglycerol kinase activity Human UniPathway:UPA00230 AGL HPA UniProtKB {GO:0005515=PMID:17908927, GO:0043033=PMID:1374391, GO:0005975=Reactome:REACT_474, GO:0007584=GO_REF:0000019, GO:0016234=GO_REF:0000019, GO:0005978=GO_REF:0000037, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0051384=GO_REF:0000019, GO:0044281=Reactome:REACT_111217, GO:0005829=Reactome:REACT_1507, GO:0005737=GO_REF:0000052, GO:0016529=GO_REF:0000019, GO:0004134=GO_REF:0000033, GO:0006006=Reactome:REACT_723, GO:0004135=GO_REF:0000033, GO:0030247=GO_REF:0000019, GO:0005980=Reactome:REACT_1008, GO:0031593=GO_REF:0000019, GO:0004133=PMID:1374391} P35573 Glycogen debranching enzyme protein 20100326 {GO:0005515=IPI, GO:0043033=TAS, GO:0005975=TAS, GO:0007584=IEA, GO:0016234=IEA, GO:0005978=IEA, GO:0005730=IDA, GO:0005634=IDA, GO:0051384=IEA, GO:0044281=TAS, GO:0005829=TAS, GO:0005737=IDA, GO:0016529=IEA, GO:0004134=IBA, GO:0006006=TAS, GO:0004135=IBA, GO:0030247=IEA, GO:0005980=TAS, GO:0031593=IEA, GO:0004133=TAS} carbohydrate metabolic process, glucose metabolic process, glycogen biosynthetic process, glycogen catabolic process, response to glucocorticoid stimulus, response to nutrient, small molecule metabolic process cytoplasm, cytosol, inclusion body, isoamylase complex, nucleolus, nucleus, sarcoplasmic reticulum 4-alpha-glucanotransferase activity, amylo-alpha-1,6-glucosidase activity, glycogen debranching enzyme activity, polysaccharide binding, polyubiquitin binding, protein binding Human AGMAT Reactome UniProtKB {GO:0005739=Reactome:REACT_14815, GO:0008295=GO_REF:0000037, GO:0034641=Reactome:REACT_13, GO:0008783=GO_REF:0000003, GO:0006595=Reactome:REACT_14820, GO:0033388=GO_REF:0000041, GO:0044281=Reactome:REACT_111217, GO:0097055=Reactome:REACT_14800, GO:0046872=GO_REF:0000037} Q9BSE5 Agmatinase, mitochondrial protein 20130301 {GO:0005739=TAS, GO:0008295=IEA, GO:0034641=TAS, GO:0008783=IEA, GO:0006595=TAS, GO:0033388=IEA, GO:0044281=TAS, GO:0097055=TAS, GO:0046872=IEA} agmatine biosynthetic process, cellular nitrogen compound metabolic process, polyamine metabolic process, putrescine biosynthetic process from arginine, small molecule metabolic process, spermidine biosynthetic process mitochondrion agmatinase activity, metal ion binding Human AGPAT1 ENSEMBL UniProtKB {GO:0005783=PMID:9461603, GO:0001819=PMID:9212163, GO:0044281=Reactome:REACT_111217, GO:0003841=GO_REF:0000019, GO:0006112=Reactome:REACT_1505, GO:0031325=Reactome:REACT_2122, GO:0001961=PMID:9212163, GO:0016024=GO_REF:0000041, GO:0005789=Reactome:REACT_2042, GO:0019432=Reactome:REACT_1190, GO:0016021=GO_REF:0000037, GO:0006644=Reactome:REACT_120870, GO:0006654=GO_REF:0000019, GO:0044255=Reactome:REACT_22279, GO:0046474=Reactome:REACT_121401} Q9HBM8 cDNA, FLJ78849, highly similar to 1-acyl-sn-glycerol-3-phosphate acyltransferase alpha (EC 2.3.1.51) protein 20130413 {GO:0005783=TAS, GO:0001819=IMP, GO:0044281=TAS, GO:0003841=IEA, GO:0006112=TAS, GO:0031325=TAS, GO:0001961=IC, GO:0016024=IEA, GO:0005789=TAS, GO:0019432=TAS, GO:0016021=IEA, GO:0006644=TAS, GO:0006654=IEA, GO:0044255=TAS, GO:0046474=TAS} CDP-diacylglycerol biosynthetic process, cellular lipid metabolic process, energy reserve metabolic process, glycerophospholipid biosynthetic process, phosphatidic acid biosynthetic process, phospholipid metabolic process, positive regulation of cellular metabolic process, positive regulation of cytokine production, positive regulation of cytokine-mediated signaling pathway, small molecule metabolic process, triglyceride biosynthetic process endoplasmic reticulum, endoplasmic reticulum membrane, integral to membrane 1-acylglycerol-3-phosphate O-acyltransferase activity Human Ensembl:ENSMUSP00000048573 AGPAT2 BHF-UCL UniProtKB {GO:0005783=GO_REF:0000024, GO:0044281=Reactome:REACT_111217, GO:0001819=PMID:9212163, GO:0003841=PMID:9212163, GO:0001961=PMID:9212163, GO:0016024=GO_REF:0000041, GO:0005789=Reactome:REACT_2042, GO:0019432=Reactome:REACT_1190, GO:0016021=GO_REF:0000037, GO:0006644=Reactome:REACT_120870, GO:0006654=PMID:9212163, GO:0044255=Reactome:REACT_22279, GO:0046474=Reactome:REACT_121401} O15120 1-acyl-sn-glycerol-3-phosphate acyltransferase beta protein 20090403 {GO:0005783=ISS, GO:0044281=TAS, GO:0001819=IMP, GO:0003841=IGI, GO:0001961=IC, GO:0016024=IEA, GO:0005789=TAS, GO:0019432=TAS, GO:0016021=IEA, GO:0006644=TAS, GO:0006654=IGI, GO:0044255=TAS, GO:0046474=TAS} CDP-diacylglycerol biosynthetic process, cellular lipid metabolic process, glycerophospholipid biosynthetic process, phosphatidic acid biosynthetic process, phospholipid metabolic process, positive regulation of cytokine production, positive regulation of cytokine-mediated signaling pathway, small molecule metabolic process, triglyceride biosynthetic process endoplasmic reticulum, endoplasmic reticulum membrane, integral to membrane 1-acylglycerol-3-phosphate O-acyltransferase activity Human AGPAT3 Reactome UniProtKB {GO:0016746=GO_REF:0000002, GO:0005886=PMID:16780588, GO:0005783=PMID:16780588, GO:0044281=Reactome:REACT_111217, GO:0005635=GO_REF:0000039, GO:0008654=PMID:15367102, GO:0003841=PMID:15367102, GO:0016024=GO_REF:0000041, GO:0005789=Reactome:REACT_2042, GO:0019432=Reactome:REACT_1190, GO:0016021=GO_REF:0000037, GO:0006644=Reactome:REACT_120870, GO:0006654=Reactome:REACT_120906, GO:0044255=Reactome:REACT_22279, GO:0046474=Reactome:REACT_121401} Q9NRZ7 1-acyl-sn-glycerol-3-phosphate acyltransferase gamma protein 20130301 {GO:0016746=IEA, GO:0005886=IDA, GO:0005783=IDA, GO:0044281=TAS, GO:0005635=IEA, GO:0008654=NAS, GO:0003841=NAS, GO:0016024=IEA, GO:0005789=TAS, GO:0019432=TAS, GO:0016021=IEA, GO:0006644=TAS, GO:0006654=TAS, GO:0044255=TAS, GO:0046474=TAS} CDP-diacylglycerol biosynthetic process, cellular lipid metabolic process, glycerophospholipid biosynthetic process, phosphatidic acid biosynthetic process, phospholipid biosynthetic process, phospholipid metabolic process, small molecule metabolic process, triglyceride biosynthetic process endoplasmic reticulum, endoplasmic reticulum membrane, integral to membrane, nuclear envelope, plasma membrane 1-acylglycerol-3-phosphate O-acyltransferase activity, transferase activity, transferring acyl groups Human AGPAT4 Reactome UniProtKB {GO:0016746=GO_REF:0000038, GO:0019432=Reactome:REACT_1190, GO:0005789=Reactome:REACT_2042, GO:0016024=GO_REF:0000041, GO:0044281=Reactome:REACT_111217, GO:0008654=PMID:15367102, GO:0016021=GO_REF:0000037, GO:0006644=Reactome:REACT_120870, GO:0006654=Reactome:REACT_120906, GO:0003841=PMID:15367102, GO:0044255=Reactome:REACT_22279, GO:0046474=Reactome:REACT_121401} Q9NRZ5 1-acyl-sn-glycerol-3-phosphate acyltransferase delta protein 20130301 {GO:0016746=IEA, GO:0019432=TAS, GO:0005789=TAS, GO:0016024=IEA, GO:0044281=TAS, GO:0008654=NAS, GO:0016021=IEA, GO:0006644=TAS, GO:0006654=TAS, GO:0003841=NAS, GO:0044255=TAS, GO:0046474=TAS} CDP-diacylglycerol biosynthetic process, cellular lipid metabolic process, glycerophospholipid biosynthetic process, phosphatidic acid biosynthetic process, phospholipid biosynthetic process, phospholipid metabolic process, small molecule metabolic process, triglyceride biosynthetic process endoplasmic reticulum membrane, integral to membrane 1-acylglycerol-3-phosphate O-acyltransferase activity, transferase activity, transferring acyl groups Human AGPAT5 Reactome UniProtKB {GO:0005741=Reactome:REACT_121245, GO:0005635=GO_REF:0000039, GO:0008654=PMID:15367102, GO:0044281=Reactome:REACT_111217, GO:0003841=PMID:15367102, GO:0005739=GO_REF:0000054, GO:0016024=GO_REF:0000041, GO:0005789=Reactome:REACT_2042, GO:0019432=Reactome:REACT_1190, GO:0016021=GO_REF:0000037, GO:0006644=Reactome:REACT_120870, GO:0006654=Reactome:REACT_120906, GO:0044255=Reactome:REACT_22279, GO:0046474=Reactome:REACT_121401} Q9NUQ2 1-acyl-sn-glycerol-3-phosphate acyltransferase epsilon protein 20130301 {GO:0005741=TAS, GO:0005635=IEA, GO:0008654=NAS, GO:0044281=TAS, GO:0003841=NAS, GO:0005739=IDA, GO:0016024=IEA, GO:0005789=TAS, GO:0019432=TAS, GO:0016021=IEA, GO:0006644=TAS, GO:0006654=TAS, GO:0044255=TAS, GO:0046474=TAS} CDP-diacylglycerol biosynthetic process, cellular lipid metabolic process, glycerophospholipid biosynthetic process, phosphatidic acid biosynthetic process, phospholipid biosynthetic process, phospholipid metabolic process, small molecule metabolic process, triglyceride biosynthetic process endoplasmic reticulum membrane, integral to membrane, mitochondrial outer membrane, mitochondrion, nuclear envelope 1-acylglycerol-3-phosphate O-acyltransferase activity Human AGPAT6 Reactome UniProtKB {GO:0006637=PMID:18238778, GO:0008610=GO_REF:0000024, GO:0005783=PMID:18238778, GO:0004366=PMID:18238778, GO:0044281=Reactome:REACT_111217, GO:0003841=PMID:18238778, GO:0007595=GO_REF:0000024, GO:0016020=PMID:18238778, GO:0040014=GO_REF:0000019, GO:0005789=Reactome:REACT_22419, GO:0006631=GO_REF:0000019, GO:0019432=Reactome:REACT_1190, GO:0016024=GO_REF:0000041, GO:0002071=GO_REF:0000019, GO:0016021=PMID:18238778, GO:0006644=Reactome:REACT_120870, GO:0006654=Reactome:REACT_120906, GO:0044255=Reactome:REACT_22279, GO:0046474=Reactome:REACT_121401, GO:0006656=PMID:18238778, GO:0046339=GO_REF:0000019} Q86UL3 Glycerol-3-phosphate acyltransferase 4 protein 20130301 {GO:0006637=IDA, GO:0008610=ISS, GO:0005783=IDA, GO:0004366=IDA, GO:0044281=TAS, GO:0003841=IDA, GO:0007595=ISS, GO:0016020=IDA, GO:0040014=IEA, GO:0005789=TAS, GO:0006631=IEA, GO:0019432=TAS, GO:0016024=IEA, GO:0002071=IEA, GO:0016021=NAS, GO:0006644=TAS, GO:0006654=TAS, GO:0044255=TAS, GO:0046474=TAS, GO:0006656=IDA, GO:0046339=IEA} CDP-diacylglycerol biosynthetic process, acyl-CoA metabolic process, cellular lipid metabolic process, diacylglycerol metabolic process, fatty acid metabolic process, glandular epithelial cell maturation, glycerophospholipid biosynthetic process, lactation, lipid biosynthetic process, phosphatidic acid biosynthetic process, phosphatidylcholine biosynthetic process, phospholipid metabolic process, regulation of multicellular organism growth, small molecule metabolic process, triglyceride biosynthetic process endoplasmic reticulum, endoplasmic reticulum membrane, integral to membrane, membrane 1-acylglycerol-3-phosphate O-acyltransferase activity, glycerol-3-phosphate O-acyltransferase activity Human AGPAT9 Reactome UniProtKB {GO:0032006=PMID:17002884, GO:0005783=PMID:17170135, GO:0016024=GO_REF:0000041, GO:0019432=Reactome:REACT_1190, GO:0005789=Reactome:REACT_2042, GO:0004366=PMID:17170135, GO:0044281=Reactome:REACT_111217, GO:0016021=GO_REF:0000037, GO:0006644=Reactome:REACT_120870, GO:0006654=Reactome:REACT_120906, GO:0044255=Reactome:REACT_22279, GO:0046474=Reactome:REACT_121401} Q53EU6 Glycerol-3-phosphate acyltransferase 3 protein 20130301 {GO:0032006=IDA, GO:0005783=IDA, GO:0016024=IEA, GO:0019432=TAS, GO:0005789=TAS, GO:0004366=IDA, GO:0044281=TAS, GO:0016021=IEA, GO:0006644=TAS, GO:0006654=TAS, GO:0044255=TAS, GO:0046474=TAS} CDP-diacylglycerol biosynthetic process, cellular lipid metabolic process, glycerophospholipid biosynthetic process, phosphatidic acid biosynthetic process, phospholipid metabolic process, regulation of TOR signaling cascade, small molecule metabolic process, triglyceride biosynthetic process endoplasmic reticulum, endoplasmic reticulum membrane, integral to membrane glycerol-3-phosphate O-acyltransferase activity Human AGPHD1 UniProtKB UniProtKB {GO:0005737=GO_REF:0000039, GO:0047992=GO_REF:0000003} A2RU49 Hydroxylysine kinase protein 20130413 {GO:0005737=IEA, GO:0047992=IEA} cytoplasm hydroxylysine kinase activity Human UniProtKB-SubCell:SL-0086 AGPS HPA UniProtKB {GO:0008610=PMID:9553082, GO:0008762=GO_REF:0000002, GO:0005782=Reactome:REACT_16930, GO:0008611=Reactome:REACT_1407, GO:0050660=GO_REF:0000002, GO:0044281=Reactome:REACT_111217, GO:0043231=GO_REF:0000052, GO:0005739=GO_REF:0000019, GO:0071949=GO_REF:0000024, GO:0008609=PMID:9553082, GO:0005778=PMID:21525035, GO:0044255=Reactome:REACT_16957, GO:0005777=PMID:9553082} O00116 Alkyldihydroxyacetonephosphate synthase, peroxisomal protein 20111111 {GO:0008610=IDA, GO:0008762=IEA, GO:0005782=TAS, GO:0008611=TAS, GO:0050660=IEA, GO:0044281=TAS, GO:0043231=IDA, GO:0005739=IEA, GO:0071949=ISS, GO:0008609=IDA, GO:0005778=IDA, GO:0044255=TAS, GO:0005777=IDA} cellular lipid metabolic process, ether lipid biosynthetic process, lipid biosynthetic process, small molecule metabolic process intracellular membrane-bounded organelle, mitochondrion, peroxisomal matrix, peroxisomal membrane, peroxisome FAD binding, UDP-N-acetylmuramate dehydrogenase activity, alkylglycerone-phosphate synthase activity, flavin adenine dinucleotide binding Human AGR2 UniProtKB UniProtKB {GO:0005515=PMID:12592373, GO:0070254=GO_REF:0000024, GO:0005739=GO_REF:0000019, GO:0002162=PMID:12592373, GO:0005783=GO_REF:0000024, GO:0005576=GO_REF:0000039} O95994 Anterior gradient protein 2 homolog protein 20120708 {GO:0005515=IPI, GO:0070254=ISS, GO:0005739=IEA, GO:0002162=IDA, GO:0005783=ISS, GO:0005576=IEA} mucus secretion endoplasmic reticulum, extracellular region, mitochondrion dystroglycan binding, protein binding Human UniProtKB:Q14118 AGR3 UniProtKB UniProtKB {GO:0005515=PMID:12592373, GO:0002162=PMID:12592373, GO:0005576=GO_REF:0000039} Q8TD06 Anterior gradient protein 3 homolog protein 20120708 {GO:0005515=IPI, GO:0002162=IDA, GO:0005576=IEA} extracellular region dystroglycan binding, protein binding Human UniProtKB:Q14118 AGRN IntAct UniProtKB {GO:0005515=PMID:21078624, GO:0002162=GO_REF:0000024, GO:0030054=GO_REF:0000037, GO:0007603=Reactome:REACT_160125, GO:0005886=Reactome:REACT_160272, GO:0045202=GO_REF:0000024, GO:0051491=GO_REF:0000024, GO:0044281=Reactome:REACT_111217, GO:0035374=GO_REF:0000024, GO:0007411=Reactome:REACT_18266, GO:0045944=GO_REF:0000024, GO:0033691=GO_REF:0000024, GO:0030204=Reactome:REACT_121206, GO:0030203=Reactome:REACT_121408, GO:0043202=Reactome:REACT_121392, GO:0005975=Reactome:REACT_474, GO:0005796=Reactome:REACT_121320, GO:0045887=GO_REF:0000024, GO:0005509=GO_REF:0000024, GO:0005605=PMID:9405491, GO:0006027=Reactome:REACT_120752, GO:0043395=GO_REF:0000024, GO:0007213=PMID:9405491, GO:0001523=Reactome:REACT_24968, GO:0006024=Reactome:REACT_121248, GO:0031012=PMID:17628813, GO:0007165=PMID:9652404, GO:0045162=PMID:9405491, GO:0050808=PMID:9652404, GO:0032321=GO_REF:0000024, GO:0043236=PMID:9652404, GO:0005200=PMID:9652404, GO:0043113=PMID:15340048, GO:0016021=GO_REF:0000037} O00468 Agrin protein 20130415 {GO:0005515=IPI, GO:0002162=ISS, GO:0030054=IEA, GO:0007603=TAS, GO:0005886=TAS, GO:0045202=ISS, GO:0051491=ISS, GO:0044281=TAS, GO:0035374=ISS, GO:0007411=TAS, GO:0045944=ISS, GO:0033691=ISS, GO:0030204=TAS, GO:0030203=TAS, GO:0043202=TAS, GO:0005975=TAS, GO:0005796=TAS, GO:0045887=ISS, GO:0005509=ISS, GO:0005605=IDA, GO:0006027=TAS, GO:0043395=ISS, GO:0007213=TAS, GO:0001523=TAS, GO:0006024=TAS, GO:0031012=IDA, GO:0007165=TAS, GO:0045162=TAS, GO:0050808=TAS, GO:0032321=ISS, GO:0043236=TAS, GO:0005200=TAS, GO:0043113=IDA, GO:0016021=IEA} G-protein coupled acetylcholine receptor signaling pathway, axon guidance, carbohydrate metabolic process, chondroitin sulfate metabolic process, clustering of voltage-gated sodium channels, glycosaminoglycan biosynthetic process, glycosaminoglycan catabolic process, glycosaminoglycan metabolic process, phototransduction, visible light, positive regulation of Rho GTPase activity, positive regulation of filopodium assembly, positive regulation of synaptic growth at neuromuscular junction, positive regulation of transcription from RNA polymerase II promoter, receptor clustering, retinoid metabolic process, signal transduction, small molecule metabolic process, synapse organization Golgi lumen, basal lamina, cell junction, extracellular matrix, integral to membrane, lysosomal lumen, plasma membrane, synapse calcium ion binding, chondroitin sulfate binding, dystroglycan binding, heparan sulfate proteoglycan binding, laminin binding, protein binding, sialic acid binding, structural constituent of cytoskeleton Human UniProtKB:O15265 AGRP PINC UniProtKB {GO:0008343=GO_REF:0000019, GO:0007631=PMID:9751529, GO:0060259=PMID:15927146, GO:0009755=GO_REF:0000002, GO:0005796=PMID:15927146, GO:0007218=PMID:15927146, GO:0005102=PMID:10318826, GO:0005184=PMID:15927146, GO:0005615=PMID:15927146} O00253 Agouti-related protein protein 20030904 {GO:0008343=IEA, GO:0007631=TAS, GO:0060259=IDA, GO:0009755=IEA, GO:0005796=IDA, GO:0007218=IDA, GO:0005102=TAS, GO:0005184=IDA, GO:0005615=IDA} adult feeding behavior, feeding behavior, hormone-mediated signaling pathway, neuropeptide signaling pathway, regulation of feeding behavior Golgi lumen, extracellular space neuropeptide hormone activity, receptor binding Human AGT BHF-UCL UniProtKB {GO:0030308=GO_REF:0000019, GO:0001658=GO_REF:0000019, GO:0009651=GO_REF:0000019, GO:0009409=GO_REF:0000019, GO:0006883=GO_REF:0000019, GO:0050731=PMID:15652490, GO:0001819=PMID:17906677, GO:0005615=GO_REF:0000024, GO:0001558=PMID:17159080, GO:0051403=GO_REF:0000019, GO:0019229=PMID:17159080, GO:0030162=GO_REF:0000033, GO:0043524=GO_REF:0000019, GO:0002019=PMID:17159080, GO:0002018=PMID:17159080, GO:0030198=GO_REF:0000019, GO:0042127=PMID:17159080, GO:0002016=PMID:17159080, GO:0048169=GO_REF:0000019, GO:0051924=GO_REF:0000019, GO:0061049=GO_REF:0000019, GO:0070371=GO_REF:0000019, GO:0044255=Reactome:REACT_22279, GO:0014061=GO_REF:0000019, GO:0045742=PMID:15652490, GO:0010744=PMID:18971559, GO:0007568=GO_REF:0000019, GO:0002034=PMID:10406457, GO:0014068=PMID:15652490, GO:0001543=GO_REF:0000019, GO:0030432=GO_REF:0000019, GO:0051387=PMID:10406457, GO:0010595=PMID:15652490, GO:0032270=PMID:18971559, GO:0010698=PMID:18971559, GO:0034374=PMID:17069818, GO:0005179=GO_REF:0000024, GO:0007186=PMID:10406457, GO:0001999=GO_REF:0000019, GO:0035815=GO_REF:0000019, GO:0001998=GO_REF:0000019, GO:0035813=PMID:17159080, GO:0045893=PMID:15153556, GO:0008083=PMID:10406457, GO:2000379=PMID:17906677, GO:0044267=Reactome:REACT_17015, GO:0051145=GO_REF:0000019, GO:0050663=GO_REF:0000019, GO:0008285=GO_REF:0000019, GO:0007263=PMID:17159080, GO:0002003=Reactome:REACT_147707, GO:0004867=GO_REF:0000033, GO:0061098=PMID:15153556, GO:0007199=PMID:17159080, GO:0010873=PMID:18971559, GO:0007267=PMID:8513325, GO:0007200=PMID:17159080, GO:0048146=GO_REF:0000024, GO:0044281=Reactome:REACT_111217, GO:0007202=GO_REF:0000019, GO:0048143=GO_REF:0000019, GO:0031702=PMID:1378723, GO:0048144=GO_REF:0000019, GO:0031703=PMID:10406457, GO:0035411=GO_REF:0000019, GO:0003331=GO_REF:0000019, GO:0051092=PMID:17906677, GO:0042311=GO_REF:0000019, GO:0040018=GO_REF:0000019, GO:0010613=GO_REF:0000024, GO:0090190=PMID:18607644, GO:0032930=GO_REF:0000019, GO:0033864=PMID:17159080, GO:0014873=GO_REF:0000024, GO:0010535=PMID:15153556, GO:0014824=GO_REF:0000019, GO:0007588=GO_REF:0000019, GO:0043065=PMID:10406457, GO:0001568=GO_REF:0000019, GO:0046622=GO_REF:0000019, GO:0007250=GO_REF:0000019, GO:0001822=PMID:16116425, GO:0045723=GO_REF:0000019, GO:0005576=Reactome:REACT_147891, GO:0006917=GO_REF:0000019, GO:0010951=GO_REF:0000033, GO:0044444=GO_REF:0000019, GO:0048659=GO_REF:0000019, GO:0008065=GO_REF:0000019, GO:0007160=GO_REF:0000019, GO:0001974=PMID:10406457, GO:0050729=PMID:17159080, GO:0034104=GO_REF:0000019, GO:0043410=GO_REF:0000019, GO:0071260=GO_REF:0000019, GO:0003051=GO_REF:0000019} P01019 Angiotensinogen protein 20090115 {GO:0030308=IEA, GO:0001658=IEA, GO:0009651=IEA, GO:0009409=IEA, GO:0006883=IEA, GO:0050731=IDA, GO:0001819=TAS, GO:0005615=ISS, GO:0001558=NAS, GO:0051403=IEA, GO:0019229=NAS, GO:0030162=IBA, GO:0043524=IEA, GO:0002019=NAS, GO:0002018=NAS, GO:0030198=IEA, GO:0042127=NAS, GO:0002016=NAS, GO:0048169=IEA, GO:0051924=IEA, GO:0061049=IEA, GO:0070371=IEA, GO:0044255=TAS, GO:0014061=IEA, GO:0045742=IDA, GO:0010744=IC, GO:0007568=IEA, GO:0002034=TAS, GO:0014068=IDA, GO:0001543=IEA, GO:0030432=IEA, GO:0051387=IDA, GO:0010595=IDA, GO:0032270=IDA, GO:0010698=IDA, GO:0034374=NAS, GO:0005179=ISS, GO:0007186=IDA, GO:0001999=IEA, GO:0035815=IEA, GO:0001998=IEA, GO:0035813=NAS, GO:0045893=IDA, GO:0008083=TAS, GO:2000379=TAS, GO:0044267=TAS, GO:0051145=IEA, GO:0050663=IEA, GO:0008285=IEA, GO:0007263=TAS, GO:0002003=TAS, GO:0004867=IBA, GO:0061098=IMP, GO:0007199=TAS, GO:0010873=IDA, GO:0007267=TAS, GO:0007200=NAS, GO:0048146=ISS, GO:0044281=TAS, GO:0007202=IEA, GO:0048143=IEA, GO:0031702=IPI, GO:0048144=IEA, GO:0031703=IPI, GO:0035411=IEA, GO:0003331=IEA, GO:0051092=TAS, GO:0042311=IEA, GO:0040018=IEA, GO:0010613=ISS, GO:0090190=IDA, GO:0032930=IEA, GO:0033864=TAS, GO:0014873=ISS, GO:0010535=IMP, GO:0014824=IEA, GO:0007588=IEA, GO:0043065=IDA, GO:0001568=IEA, GO:0046622=IEA, GO:0007250=IEA, GO:0001822=IMP, GO:0045723=IEA, GO:0005576=TAS, GO:0006917=IEA, GO:0010951=IBA, GO:0044444=IEA, GO:0048659=IEA, GO:0008065=IEA, GO:0007160=IEA, GO:0001974=TAS, GO:0050729=TAS, GO:0034104=IEA, GO:0043410=IEA, GO:0071260=IEA, GO:0003051=IEA} ERK1 and ERK2 cascade, G-protein coupled receptor signaling pathway, G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger, activation of NF-kappaB-inducing kinase activity, activation of phospholipase C activity, aging, angiotensin maturation, angiotensin mediated vasoconstriction involved in regulation of systemic arterial blood pressure, angiotensin-mediated drinking behavior, artery smooth muscle contraction, astrocyte activation, blood vessel development, blood vessel remodeling, branching involved in ureteric bud morphogenesis, catenin import into nucleus, cell growth involved in cardiac muscle cell development, cell-cell signaling, cell-matrix adhesion, cellular lipid metabolic process, cellular protein metabolic process, cellular response to mechanical stimulus, cellular sodium ion homeostasis, cytokine secretion, establishment of blood-nerve barrier, excretion, extracellular matrix organization, fibroblast proliferation, induction of apoptosis, kidney development, low-density lipoprotein particle remodeling, negative regulation of cell growth, negative regulation of cell proliferation, negative regulation of endopeptidase activity, negative regulation of neuron apoptotic process, negative regulation of neurotrophin TRK receptor signaling pathway, negative regulation of tissue remodeling, nitric oxide mediated signal transduction, ovarian follicle rupture, peristalsis, phospholipase C-activating G-protein coupled receptor signaling pathway, positive regulation of MAPK cascade, positive regulation of NAD(P)H oxidase activity, positive regulation of NF-kappaB transcription factor activity, positive regulation of activation of JAK2 kinase activity, positive regulation of apoptotic process, positive regulation of branching involved in ureteric bud morphogenesis, positive regulation of cardiac muscle hypertrophy, positive regulation of cellular protein metabolic process, positive regulation of cholesterol esterification, positive regulation of cytokine production, positive regulation of endothelial cell migration, positive regulation of epidermal growth factor receptor signaling pathway, positive regulation of extracellular matrix constituent secretion, positive regulation of fatty acid biosynthetic process, positive regulation of fibroblast proliferation, positive regulation of inflammatory response, positive regulation of macrophage derived foam cell differentiation, positive regulation of multicellular organism growth, positive regulation of organ growth, positive regulation of peptidyl-tyrosine phosphorylation, positive regulation of phosphatidylinositol 3-kinase cascade, positive regulation of protein tyrosine kinase activity, positive regulation of reactive oxygen species metabolic process, positive regulation of renal sodium excretion, positive regulation of superoxide anion generation, positive regulation of transcription, DNA-dependent, regulation of blood vessel size by renin-angiotensin, regulation of blood volume by renin-angiotensin, regulation of calcium ion transport, regulation of cell growth, regulation of cell proliferation, regulation of long-term neuronal synaptic plasticity, regulation of norepinephrine secretion, regulation of proteolysis, regulation of renal output by angiotensin, regulation of renal sodium excretion, regulation of vasoconstriction, renal response to blood flow involved in circulatory renin-angiotensin regulation of systemic arterial blood pressure, renin-angiotensin regulation of aldosterone production, response to cold, response to muscle activity involved in regulation of muscle adaptation, response to salt stress, small molecule metabolic process, smooth muscle cell differentiation, smooth muscle cell proliferation, stress-activated MAPK cascade, vasodilation cytoplasmic part, extracellular region, extracellular space acetyltransferase activator activity, growth factor activity, hormone activity, serine-type endopeptidase inhibitor activity, type 1 angiotensin receptor binding, type 2 angiotensin receptor binding Human AGTPBP1 UniProtKB UniProtKB {GO:0001754=GO_REF:0000024, GO:0035610=GO_REF:0000024, GO:0060041=GO_REF:0000019, GO:0005634=GO_REF:0000039, GO:0035609=GO_REF:0000024, GO:0005829=GO_REF:0000024, GO:0005739=GO_REF:0000024, GO:0050905=GO_REF:0000024, GO:0015631=GO_REF:0000024, GO:0021772=GO_REF:0000024, GO:0021702=GO_REF:0000024, GO:0006508=GO_REF:0000037, GO:0007628=GO_REF:0000019, GO:0008270=GO_REF:0000002, GO:0007005=GO_REF:0000024, GO:0042133=GO_REF:0000019, GO:0004181=GO_REF:0000024} Q9UPW5 Cytosolic carboxypeptidase 1 protein 20101123 {GO:0001754=ISS, GO:0035610=ISS, GO:0060041=IEA, GO:0005634=IEA, GO:0035609=ISS, GO:0005829=ISS, GO:0005739=ISS, GO:0050905=ISS, GO:0015631=ISS, GO:0021772=ISS, GO:0021702=ISS, GO:0006508=IEA, GO:0007628=IEA, GO:0008270=IEA, GO:0007005=ISS, GO:0042133=IEA, GO:0004181=ISS} C-terminal protein deglutamylation, adult walking behavior, cerebellar Purkinje cell differentiation, eye photoreceptor cell differentiation, mitochondrion organization, neuromuscular process, neurotransmitter metabolic process, olfactory bulb development, protein side chain deglutamylation, proteolysis, retina development in camera-type eye cytosol, mitochondrion, nucleus metallocarboxypeptidase activity, tubulin binding, zinc ion binding Human UniProtKB:Q641K1 AGTR1 GOC UniProtKB {GO:0005515=PMID:19023134, GO:0004945=PMID:1567413, GO:0019722=PMID:1567413, GO:0005886=Reactome:REACT_22436, GO:0010873=PMID:18971559, GO:0007200=PMID:17159080, GO:0086097=PMID:1378723, GO:0007266=PMID:15611106, GO:0001558=PMID:17159080, GO:0007204=PMID:1567413, GO:0032430=PMID:17069818, GO:0019229=PMID:1378723, GO:0042312=PMID:1378723, GO:0003081=PMID:1378723, GO:0002018=PMID:17159080, GO:0042127=PMID:17159080, GO:0051482=PMID:1567413, GO:0033864=PMID:17159080, GO:0031711=PMID:10993080, GO:0046982=PMID:10993080, GO:0010744=PMID:18971559, GO:0001822=PMID:16116425, GO:0050727=PMID:1378723, GO:0002034=PMID:10993080, GO:0032270=PMID:18971559, GO:0010698=PMID:18971559, GO:0034374=PMID:17069818, GO:0007186=PMID:1378723, GO:0005887=PMID:1378723, GO:0060326=PMID:15635042, GO:0050729=PMID:17159080, GO:0035813=PMID:17159080, GO:0016021=PMID:8135787, GO:2000379=PMID:17159080, GO:0001596=PMID:10993080} P30556 Type-1 angiotensin II receptor protein 20130413 {GO:0005515=IPI, GO:0004945=IDA, GO:0019722=IDA, GO:0005886=TAS, GO:0010873=IMP, GO:0007200=NAS, GO:0086097=IPI, GO:0007266=IDA, GO:0001558=NAS, GO:0007204=IDA, GO:0032430=IMP, GO:0019229=IC, GO:0042312=IC, GO:0003081=IC, GO:0002018=NAS, GO:0042127=NAS, GO:0051482=IDA, GO:0033864=TAS, GO:0031711=IPI, GO:0046982=IPI, GO:0010744=IC, GO:0001822=IMP, GO:0050727=IC, GO:0002034=IC, GO:0032270=IMP, GO:0010698=IMP, GO:0034374=NAS, GO:0007186=IDA, GO:0005887=IC, GO:0060326=IDA, GO:0050729=TAS, GO:0035813=NAS, GO:0016021=NAS, GO:2000379=TAS, GO:0001596=IDA} G-protein coupled receptor signaling pathway, Rho protein signal transduction, calcium-mediated signaling, cell chemotaxis, elevation of cytosolic calcium ion concentration, elevation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway, kidney development, low-density lipoprotein particle remodeling, phospholipase C-activating G-protein coupled receptor signaling pathway, phospholipase C-activating angiotensin-mediated signaling pathway, positive regulation of NAD(P)H oxidase activity, positive regulation of cellular protein metabolic process, positive regulation of cholesterol esterification, positive regulation of inflammatory response, positive regulation of macrophage derived foam cell differentiation, positive regulation of phospholipase A2 activity, positive regulation of reactive oxygen species metabolic process, regulation of blood vessel size by renin-angiotensin, regulation of cell growth, regulation of cell proliferation, regulation of inflammatory response, regulation of renal sodium excretion, regulation of systemic arterial blood pressure by renin-angiotensin, regulation of vasoconstriction, regulation of vasodilation, renin-angiotensin regulation of aldosterone production integral to membrane, integral to plasma membrane, plasma membrane acetyltransferase activator activity, angiotensin type I receptor activity, angiotensin type II receptor activity, bradykinin receptor binding, protein binding, protein heterodimerization activity Human UniProtKB:P01019 AGTR2 GOC UniProtKB {GO:0005515=PMID:18344519, GO:0030308=PMID:17159080, GO:0004945=PMID:10406457, GO:0021695=GO_REF:0000019, GO:0006883=GO_REF:0000019, GO:0042990=GO_REF:0000019, GO:0007243=PMID:17000928, GO:0001991=GO_REF:0000024, GO:0002018=GO_REF:0000019, GO:0061049=GO_REF:0000019, GO:0007610=PMID:12089445, GO:0072300=GO_REF:0000019, GO:0048019=PMID:17159079, GO:0010459=GO_REF:0000024, GO:0002033=GO_REF:0000019, GO:0010243=GO_REF:0000019, GO:0002035=GO_REF:0000019, GO:0010700=GO_REF:0000019, GO:0051387=PMID:10406457, GO:0007186=PMID:10406457, GO:1900116=PMID:17159079, GO:0007420=PMID:12089445, GO:0005887=PMID:10406457, GO:0051000=PMID:17000928, GO:0035815=GO_REF:0000019, GO:0035566=GO_REF:0000019, GO:0045893=GO_REF:0000019, GO:0043537=PMID:15710780, GO:0008134=GO_REF:0000019, GO:0048471=GO_REF:0000019, GO:0008284=GO_REF:0000019, GO:0005886=Reactome:REACT_22289, GO:0007263=PMID:17159080, GO:0007199=PMID:17000928, GO:0048147=GO_REF:0000019, GO:0050715=GO_REF:0000019, GO:0045429=PMID:17000928, GO:0042416=GO_REF:0000019, GO:0006954=GO_REF:0000019, GO:0045909=PMID:17159079, GO:0090190=GO_REF:0000019, GO:0035932=GO_REF:0000019, GO:0043065=PMID:10406457, GO:0005576=PMID:17159079, GO:0001974=PMID:17159080, GO:0008217=PMID:7477266, GO:0032516=PMID:10406457, GO:0017046=GO_REF:0000019, GO:0007166=PMID:10406457, GO:0071549=GO_REF:0000019} P50052 Type-2 angiotensin II receptor protein 20130413 {GO:0005515=IPI, GO:0030308=TAS, GO:0004945=IPI, GO:0021695=IEA, GO:0006883=IEA, GO:0042990=IEA, GO:0007243=ISS, GO:0001991=ISS, GO:0002018=IEA, GO:0061049=IEA, GO:0007610=IMP, GO:0072300=IEA, GO:0048019=TAS, GO:0010459=ISS, GO:0002033=IEA, GO:0010243=IEA, GO:0002035=IEA, GO:0010700=IEA, GO:0051387=IMP, GO:0007186=IC, GO:1900116=TAS, GO:0007420=NAS, GO:0005887=IC, GO:0051000=ISS, GO:0035815=IEA, GO:0035566=IEA, GO:0045893=IEA, GO:0043537=NAS, GO:0008134=IEA, GO:0048471=IEA, GO:0008284=IEA, GO:0005886=TAS, GO:0007263=TAS, GO:0007199=ISS, GO:0048147=IEA, GO:0050715=IEA, GO:0045429=IC, GO:0042416=IEA, GO:0006954=IEA, GO:0045909=IDA, GO:0090190=IEA, GO:0035932=IEA, GO:0043065=IMP, GO:0005576=TAS, GO:0001974=TAS, GO:0008217=TAS, GO:0032516=IDA, GO:0017046=IEA, GO:0007166=IDA, GO:0071549=IEA} G-protein coupled receptor signaling pathway, G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger, aldosterone secretion, behavior, blood vessel remodeling, brain development, brain renin-angiotensin system, cell growth involved in cardiac muscle cell development, cell surface receptor signaling pathway, cellular response to dexamethasone stimulus, cellular sodium ion homeostasis, cerebellar cortex development, dopamine biosynthetic process, extracellular negative regulation of signal transduction, inflammatory response, intracellular protein kinase cascade, negative regulation of blood vessel endothelial cell migration, negative regulation of cell growth, negative regulation of fibroblast proliferation, negative regulation of heart rate, negative regulation of neurotrophin TRK receptor signaling pathway, negative regulation of norepinephrine secretion, nitric oxide mediated signal transduction, positive regulation of apoptotic process, positive regulation of branching involved in ureteric bud morphogenesis, positive regulation of cell proliferation, positive regulation of cytokine secretion, positive regulation of metanephric glomerulus development, positive regulation of nitric oxide biosynthetic process, positive regulation of nitric-oxide synthase activity, positive regulation of phosphoprotein phosphatase activity, positive regulation of renal sodium excretion, positive regulation of transcription, DNA-dependent, positive regulation of vasodilation, regulation of blood pressure, regulation of metanephros size, regulation of systemic arterial blood pressure by circulatory renin-angiotensin, regulation of transcription factor import into nucleus, renin-angiotensin regulation of aldosterone production, response to organic nitrogen, vasodilation by angiotensin involved in regulation of systemic arterial blood pressure extracellular region, integral to plasma membrane, perinuclear region of cytoplasm, plasma membrane angiotensin type II receptor activity, peptide hormone binding, protein binding, receptor antagonist activity, transcription factor binding Human AGTRAP HPA UniProtKB {GO:0005515=PMID:19060904, GO:0001666=GO_REF:0000019, GO:0004945=GO_REF:0000019, GO:0000139=GO_REF:0000039, GO:0005886=GO_REF:0000019, GO:0005789=GO_REF:0000039, GO:0008217=GO_REF:0000019, GO:0016021=GO_REF:0000037, GO:0005938=GO_REF:0000019, GO:0030659=GO_REF:0000039, GO:0043231=GO_REF:0000052} Q6RW13 Type-1 angiotensin II receptor-associated protein protein 20111111 {GO:0005515=IPI, GO:0001666=IEA, GO:0004945=IEA, GO:0000139=IEA, GO:0005886=IEA, GO:0005789=IEA, GO:0008217=IEA, GO:0016021=IEA, GO:0005938=IEA, GO:0030659=IEA, GO:0043231=IDA} regulation of blood pressure, response to hypoxia Golgi membrane, cell cortex, cytoplasmic vesicle membrane, endoplasmic reticulum membrane, integral to membrane, intracellular membrane-bounded organelle, plasma membrane angiotensin type II receptor activity, protein binding Human AGXT HGNC UniProtKB {GO:0005515=PMID:15911627, GO:0046724=GO_REF:0000019, GO:0006625=PMID:1703535, GO:0005782=Reactome:REACT_16972, GO:0005102=PMID:20178365, GO:0008483=PMID:20133649, GO:0051384=GO_REF:0000019, GO:0044281=Reactome:REACT_111217, GO:0051591=GO_REF:0000019, GO:0042803=PMID:12899834, GO:0019265=PMID:22198249, GO:0008453=Reactome:REACT_16972, GO:0034641=Reactome:REACT_13, GO:0005759=GO_REF:0000039, GO:0030170=PMID:15802217, GO:0042853=PMID:17696873, GO:0046487=PMID:3709805, GO:0042866=GO_REF:0000019, GO:0009436=PMID:22198249, GO:0019448=PMID:18492492, GO:0004760=GO_REF:0000003, GO:0005777=PMID:7813517} P21549 Serine--pyruvate aminotransferase protein 20061208 {GO:0005515=IPI, GO:0046724=IEA, GO:0006625=IMP, GO:0005782=TAS, GO:0005102=IPI, GO:0008483=IDA, GO:0051384=IEA, GO:0044281=TAS, GO:0051591=IEA, GO:0042803=IDA, GO:0019265=IDA, GO:0008453=TAS, GO:0034641=TAS, GO:0005759=IEA, GO:0030170=IMP, GO:0042853=IDA, GO:0046487=IMP, GO:0042866=IEA, GO:0009436=IDA, GO:0019448=IDA, GO:0004760=IEA, GO:0005777=IDA} L-alanine catabolic process, L-cysteine catabolic process, cellular nitrogen compound metabolic process, glycine biosynthetic process, by transamination of glyoxylate, glyoxylate catabolic process, glyoxylate metabolic process, oxalic acid secretion, protein targeting to peroxisome, pyruvate biosynthetic process, response to cAMP, response to glucocorticoid stimulus, small molecule metabolic process mitochondrial matrix, peroxisomal matrix, peroxisome alanine-glyoxylate transaminase activity, protein binding, protein homodimerization activity, pyridoxal phosphate binding, receptor binding, serine-pyruvate transaminase activity, transaminase activity Human AGXT2 BHF-UCL UniProtKB {GO:0016223=GO_REF:0000019, GO:0008483=GO_REF:0000002, GO:0055086=Reactome:REACT_1698, GO:0044281=Reactome:REACT_111217, GO:0019265=PMID:20018850, GO:0008453=Reactome:REACT_25087, GO:0045429=PMID:20018850, GO:0005739=PMID:20018850, GO:0034641=Reactome:REACT_13, GO:0046135=Reactome:REACT_1023, GO:0005759=Reactome:REACT_25087, GO:0019481=PMID:20018850, GO:0030170=GO_REF:0000002, GO:0047305=GO_REF:0000003, GO:0046487=Reactome:REACT_16925, GO:0009436=PMID:20018850, GO:0006206=Reactome:REACT_957} Q9BYV1 Alanine--glyoxylate aminotransferase 2, mitochondrial protein 20120523 {GO:0016223=IEA, GO:0008483=IEA, GO:0055086=TAS, GO:0044281=TAS, GO:0019265=IDA, GO:0008453=TAS, GO:0045429=IDA, GO:0005739=IDA, GO:0034641=TAS, GO:0046135=TAS, GO:0005759=TAS, GO:0019481=IDA, GO:0030170=IEA, GO:0047305=IEA, GO:0046487=TAS, GO:0009436=IDA, GO:0006206=TAS} L-alanine catabolic process, by transamination, cellular nitrogen compound metabolic process, glycine biosynthetic process, by transamination of glyoxylate, glyoxylate catabolic process, glyoxylate metabolic process, nucleobase-containing small molecule metabolic process, positive regulation of nitric oxide biosynthetic process, pyrimidine nucleobase metabolic process, pyrimidine nucleoside catabolic process, small molecule metabolic process mitochondrial matrix, mitochondrion (R)-3-amino-2-methylpropionate-pyruvate transaminase activity, alanine-glyoxylate transaminase activity, beta-alanine-pyruvate transaminase activity, pyridoxal phosphate binding, transaminase activity Human AGXT2L1 UniProtKB UniProtKB {GO:0005739=GO_REF:0000039, GO:0006520=GO_REF:0000029, GO:0030170=GO_REF:0000002, GO:0050459=GO_REF:0000003, GO:0008483=GO_REF:0000002, GO:0005575=GO_REF:0000015, GO:0008453=GO_REF:0000029} Q8TBG4 Ethanolamine-phosphate phospho-lyase protein 20070906 {GO:0005739=IEA, GO:0006520=NAS, GO:0030170=IEA, GO:0050459=IEA, GO:0008483=IEA, GO:0005575=ND, GO:0008453=NAS} cellular amino acid metabolic process cellular_component, mitochondrion alanine-glyoxylate transaminase activity, ethanolamine-phosphate phospho-lyase activity, pyridoxal phosphate binding, transaminase activity Human AGXT2L2 UniProtKB UniProtKB {GO:0005739=GO_REF:0000039, GO:0030170=GO_REF:0000002, GO:0008483=GO_REF:0000037, GO:0016829=GO_REF:0000037} Q8IUZ5 5-phosphohydroxy-L-lysine phospho-lyase protein 20130413 {GO:0005739=IEA, GO:0030170=IEA, GO:0008483=IEA, GO:0016829=IEA} mitochondrion lyase activity, pyridoxal phosphate binding, transaminase activity Human UniProtKB-SubCell:SL-0173 AHCTF1 HPA UniProtKB {GO:0000236=Reactome:REACT_682, GO:0031965=GO_REF:0000052, GO:0003700=GO_REF:0000019, GO:0005634=GO_REF:0000052, GO:0015031=GO_REF:0000037, GO:0051292=PMID:17098863, GO:0003677=GO_REF:0000037, GO:0016363=GO_REF:0000039, GO:0005829=Reactome:REACT_150414, GO:0000910=PMID:17098863, GO:0005737=GO_REF:0000019, GO:0005643=PMID:17098863, GO:0000087=Reactome:REACT_910, GO:0031080=PMID:17098863, GO:0000777=PMID:17098863, GO:0005654=GO_REF:0000039, GO:0051028=GO_REF:0000037, GO:0000278=Reactome:REACT_152, GO:0000090=Reactome:REACT_1275, GO:0000785=PMID:17098863} Q8WYP5 Protein ELYS protein 20101115 {GO:0000236=TAS, GO:0031965=IDA, GO:0003700=IEA, GO:0005634=IDA, GO:0015031=IEA, GO:0051292=IMP, GO:0003677=IEA, GO:0016363=IEA, GO:0005829=TAS, GO:0000910=IMP, GO:0005737=IEA, GO:0005643=IDA, GO:0000087=TAS, GO:0031080=IDA, GO:0000777=IDA, GO:0005654=IEA, GO:0051028=IEA, GO:0000278=TAS, GO:0000090=TAS, GO:0000785=IDA} M phase of mitotic cell cycle, cytokinesis, mRNA transport, mitotic anaphase, mitotic cell cycle, mitotic prometaphase, nuclear pore complex assembly, protein transport chromatin, condensed chromosome kinetochore, cytoplasm, cytosol, nuclear matrix, nuclear membrane, nuclear pore, nuclear pore outer ring, nucleoplasm, nucleus DNA binding, sequence-specific DNA binding transcription factor activity Human AHCY Reactome UniProtKB {GO:0004013=Reactome:REACT_6756, GO:0034641=Reactome:REACT_13, GO:0042470=GO_REF:0000039, GO:0005737=GO_REF:0000029, GO:0006805=Reactome:REACT_13433, GO:0000096=Reactome:REACT_115639, GO:0044281=Reactome:REACT_111217, GO:0032259=Reactome:REACT_6946, GO:0006730=GO_REF:0000029, GO:0005829=Reactome:REACT_6756} P23526 Adenosylhomocysteinase protein 20130213 {GO:0004013=TAS, GO:0034641=TAS, GO:0042470=IEA, GO:0005737=NAS, GO:0006805=TAS, GO:0000096=TAS, GO:0044281=TAS, GO:0032259=TAS, GO:0006730=NAS, GO:0005829=TAS} cellular nitrogen compound metabolic process, methylation, one-carbon metabolic process, small molecule metabolic process, sulfur amino acid metabolic process, xenobiotic metabolic process cytoplasm, cytosol, melanosome adenosylhomocysteinase activity Human AHCYL1 IntAct UniProtKB {GO:0005515=PMID:22190034, GO:0004013=GO_REF:0000003, GO:0006378=GO_REF:0000019, GO:0044070=GO_REF:0000019, GO:0005783=GO_REF:0000039, GO:0010765=GO_REF:0000019, GO:0006611=GO_REF:0000019, GO:0031440=GO_REF:0000019, GO:0006730=GO_REF:0000037, GO:0032412=GO_REF:0000019} O43865 Putative adenosylhomocysteinase 2 protein 20130415 {GO:0005515=IPI, GO:0004013=IEA, GO:0006378=IEA, GO:0044070=IEA, GO:0005783=IEA, GO:0010765=IEA, GO:0006611=IEA, GO:0031440=IEA, GO:0006730=IEA, GO:0032412=IEA} mRNA polyadenylation, one-carbon metabolic process, positive regulation of sodium ion transport, protein export from nucleus, regulation of anion transport, regulation of ion transmembrane transporter activity, regulation of mRNA 3'-end processing endoplasmic reticulum adenosylhomocysteinase activity, protein binding Human UniProtKB:P04608 AHCYL2 UniProtKB UniProtKB {GO:0004013=GO_REF:0000003, GO:0006730=GO_REF:0000037} Q96HN2 Putative adenosylhomocysteinase 3 protein 20130413 {GO:0004013=IEA, GO:0006730=IEA} one-carbon metabolic process adenosylhomocysteinase activity Human EC:3.3.1.1 AHDC1 UniProtKB UniProtKB {GO:0003677=GO_REF:0000037} Q5TGY3 AT-hook DNA-binding motif-containing protein 1 protein 20130413 {GO:0003677=IEA} DNA binding Human UniProtKB-KW:KW-0238 AHI1 IntAct UniProtKB {GO:0005515=PMID:22623184, GO:0036038=GO_REF:0000024, GO:0070986=GO_REF:0000024, GO:0001738=GO_REF:0000024, GO:0035844=GO_REF:0000024, GO:0001947=GO_REF:0000024, GO:0035845=GO_REF:0000024, GO:0045944=GO_REF:0000024, GO:0039008=GO_REF:0000024, GO:0016192=GO_REF:0000024, GO:0043066=GO_REF:0000024, GO:0033365=GO_REF:0000019, GO:0005814=GO_REF:0000024, GO:0071599=GO_REF:0000024, GO:0039023=GO_REF:0000024, GO:0031513=GO_REF:0000024, GO:0010842=GO_REF:0000024, GO:0007417=GO_REF:0000024, GO:0070121=GO_REF:0000024, GO:0065001=GO_REF:0000024, GO:0005929=GO_REF:0000024, GO:0042384=GO_REF:0000024, GO:0050795=GO_REF:0000024, GO:0060271=GO_REF:0000024, GO:0030862=GO_REF:0000024, GO:0034613=GO_REF:0000024, GO:0030902=GO_REF:0000024, GO:0007169=GO_REF:0000024, GO:0002092=GO_REF:0000024} Q8N157 Jouberin protein 20130415 {GO:0005515=IPI, GO:0036038=ISS, GO:0070986=ISS, GO:0001738=ISS, GO:0035844=ISS, GO:0001947=ISS, GO:0035845=ISS, GO:0045944=ISS, GO:0039008=ISS, GO:0016192=ISS, GO:0043066=ISS, GO:0033365=IEA, GO:0005814=ISS, GO:0071599=ISS, GO:0039023=ISS, GO:0031513=ISS, GO:0010842=ISS, GO:0007417=ISS, GO:0070121=ISS, GO:0065001=ISS, GO:0005929=ISS, GO:0042384=ISS, GO:0050795=ISS, GO:0060271=ISS, GO:0030862=ISS, GO:0034613=ISS, GO:0030902=ISS, GO:0007169=ISS, GO:0002092=ISS} Kupffer's vesicle development, cellular protein localization, central nervous system development, cilium assembly, cilium morphogenesis, cloaca development, heart looping, hindbrain development, left/right axis specification, morphogenesis of a polarized epithelium, negative regulation of apoptotic process, otic vesicle development, photoreceptor cell outer segment organization, positive regulation of polarized epithelial cell differentiation, positive regulation of receptor internalization, positive regulation of transcription from RNA polymerase II promoter, pronephric duct morphogenesis, pronephric nephron tubule morphogenesis, protein localization to organelle, regulation of behavior, retina layer formation, specification of axis polarity, transmembrane receptor protein tyrosine kinase signaling pathway, vesicle-mediated transport TCTN-B9D complex, centriole, cilium, nonmotile primary cilium protein binding Human UniProtKB:P50570 AHNAK UniProtKB UniProtKB {GO:0005515=PMID:16417406, GO:0005634=PMID:1608957, GO:0007399=GO_REF:0000029} Q09666 Neuroblast differentiation-associated protein AHNAK protein 20101006 {GO:0005515=IPI, GO:0005634=NAS, GO:0007399=NAS} nervous system development nucleus protein binding Human UniProtKB:P55160 AHNAK2 UniProtKB UniProtKB {GO:0005634=GO_REF:0000039} Q8IVF2 Protein AHNAK2 protein 20130413 {GO:0005634=IEA} nucleus Human UniProtKB-SubCell:SL-0191 AHR GOC UniProtKB {GO:0005515=PMID:9079689, GO:0010468=PMID:15681594, GO:0003700=PMID:11782478, GO:0006805=PMID:19538249, GO:0044212=PMID:15681594, GO:0006366=PMID:10395741, GO:0045899=GO_REF:0000019, GO:0003705=GO_REF:0000019, GO:0051879=PMID:9079689, GO:0005634=GO_REF:0000052, GO:0005737=GO_REF:0000052, GO:0046983=PMID:19538249, GO:0030850=GO_REF:0000019, GO:0004879=PMID:10395741, GO:0009410=PMID:7961644, GO:0005667=PMID:19538249, GO:0006355=PMID:10395741, GO:0001568=PMID:19538249, GO:0006357=PMID:15681594, GO:0046982=PMID:19538249, GO:0005730=GO_REF:0000052, GO:0006950=PMID:7961644, GO:0006915=PMID:12213388, GO:0030888=PMID:15681594, GO:0000122=GO_REF:0000019, GO:0003677=PMID:19538249, GO:0043565=GO_REF:0000019, GO:0007049=PMID:12213388, GO:0034752=PMID:19538249, GO:0030522=PMID:10395741, GO:0008134=PMID:9079689} P35869 Aryl hydrocarbon receptor protein 20130413 {GO:0005515=IPI, GO:0010468=IDA, GO:0003700=IDA, GO:0006805=TAS, GO:0044212=IDA, GO:0006366=IDA, GO:0045899=IEA, GO:0003705=IEA, GO:0051879=IDA, GO:0005634=IDA, GO:0005737=IDA, GO:0046983=TAS, GO:0030850=IEA, GO:0004879=IDA, GO:0009410=IDA, GO:0005667=TAS, GO:0006355=IDA, GO:0001568=NAS, GO:0006357=IDA, GO:0046982=TAS, GO:0005730=IDA, GO:0006950=IDA, GO:0006915=TAS, GO:0030888=IDA, GO:0000122=IEA, GO:0003677=TAS, GO:0043565=IEA, GO:0007049=TAS, GO:0034752=TAS, GO:0030522=IDA, GO:0008134=IPI} apoptotic process, blood vessel development, cell cycle, intracellular receptor signaling pathway, negative regulation of transcription from RNA polymerase II promoter, positive regulation of RNA polymerase II transcriptional preinitiation complex assembly, prostate gland development, regulation of B cell proliferation, regulation of gene expression, regulation of transcription from RNA polymerase II promoter, regulation of transcription, DNA-dependent, response to stress, response to xenobiotic stimulus, transcription from RNA polymerase II promoter, xenobiotic metabolic process cytoplasm, cytosolic aryl hydrocarbon receptor complex, nucleolus, nucleus, transcription factor complex DNA binding, Hsp90 protein binding, RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity, ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity, protein binding, protein dimerization activity, protein heterodimerization activity, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, transcription factor binding, transcription regulatory region DNA binding Human AHRR InterPro UniProtKB {GO:0005737=GO_REF:0000039, GO:0033235=GO_REF:0000019, GO:0046983=GO_REF:0000002, GO:0005634=GO_REF:0000019, GO:0000122=GO_REF:0000019, GO:0004871=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} G3V143 Aryl hydrocarbon receptor repressor protein 20130413 {GO:0005737=IEA, GO:0033235=IEA, GO:0046983=IEA, GO:0005634=IEA, GO:0000122=IEA, GO:0004871=IEA, GO:0003677=IEA, GO:0006351=IEA} negative regulation of transcription from RNA polymerase II promoter, positive regulation of protein sumoylation, transcription, DNA-dependent cytoplasm, nucleus DNA binding, protein dimerization activity, signal transducer activity Human InterPro:IPR011598 AHSA1 GOC UniProtKB {GO:0005515=PMID:19875381, GO:0005737=GO_REF:0000052, GO:0006457=GO_REF:0000024, GO:0005783=GO_REF:0000039, GO:0006950=GO_REF:0000024, GO:0051087=PMID:12504007, GO:0032781=PMID:12504007, GO:0001671=PMID:12504007, GO:0005829=GO_REF:0000039} O95433 Activator of 90 kDa heat shock protein ATPase homolog 1 protein 20130413 {GO:0005515=IPI, GO:0005737=IDA, GO:0006457=ISS, GO:0005783=IEA, GO:0006950=ISS, GO:0051087=IDA, GO:0032781=IDA, GO:0001671=IDA, GO:0005829=IEA} positive regulation of ATPase activity, protein folding, response to stress cytoplasm, cytosol, endoplasmic reticulum ATPase activator activity, chaperone binding, protein binding Human AHSA2 UniProtKB UniProtKB {GO:0006950=GO_REF:0000037, GO:0051087=GO_REF:0000002, GO:0001671=GO_REF:0000002} Q719I0 Activator of 90 kDa heat shock protein ATPase homolog 2 protein 20130413 {GO:0006950=IEA, GO:0051087=IEA, GO:0001671=IEA} response to stress ATPase activator activity, chaperone binding Human UniProtKB-KW:KW-0346 AHSG GOC UniProtKB {GO:0030500=PMID:3474608, GO:0006907=PMID:12773197, GO:0004869=GO_REF:0000002, GO:0019210=PMID:12203945, GO:0046627=PMID:12153747, GO:0050727=PMID:12642050, GO:0005576=PMID:14718574, GO:0006953=PMID:12153747, GO:0030502=GO_REF:0000024, GO:0005615=PMID:11922920, GO:0042326=PMID:12203945, GO:0050766=PMID:12725640, GO:0001501=PMID:12153747, GO:0001503=GO_REF:0000019} P02765 Alpha-2-HS-glycoprotein protein 20130413 {GO:0030500=NAS, GO:0006907=NAS, GO:0004869=IEA, GO:0019210=NAS, GO:0046627=NAS, GO:0050727=IMP, GO:0005576=NAS, GO:0006953=IDA, GO:0030502=ISS, GO:0005615=NAS, GO:0042326=NAS, GO:0050766=IDA, GO:0001501=NAS, GO:0001503=IEA} acute-phase response, negative regulation of bone mineralization, negative regulation of insulin receptor signaling pathway, negative regulation of phosphorylation, ossification, pinocytosis, positive regulation of phagocytosis, regulation of bone mineralization, regulation of inflammatory response, skeletal system development extracellular region, extracellular space cysteine-type endopeptidase inhibitor activity, kinase inhibitor activity Human AHSP UniProtKB UniProtKB {GO:0030097=PMID:12066189, GO:0030492=PMID:12066189, GO:0020027=PMID:12066189, GO:0005833=PMID:12066189, GO:0006457=GO_REF:0000002, GO:0050821=GO_REF:0000002, GO:0051082=PMID:12066189} Q9NZD4 Alpha-hemoglobin-stabilizing protein protein 20040806 {GO:0030097=NAS, GO:0030492=NAS, GO:0020027=NAS, GO:0005833=NAS, GO:0006457=IEA, GO:0050821=IEA, GO:0051082=NAS} hemoglobin metabolic process, hemopoiesis, protein folding, protein stabilization hemoglobin complex hemoglobin binding, unfolded protein binding Human AICDA IntAct UniProtKB {GO:0016814=GO_REF:0000002, GO:0006397=GO_REF:0000037, GO:0005515=PMID:21722948, GO:0045190=GO_REF:0000019, GO:0005634=PMID:14769937, GO:0016445=PMID:18722174, GO:0090310=PMID:21496894, GO:0000178=PMID:21255825, GO:0005737=GO_REF:0000054, GO:0071222=GO_REF:0000019, GO:0030183=PMID:11007475, GO:0080111=PMID:21496894, GO:0004126=PMID:18722174, GO:0008270=GO_REF:0000002} Q9GZX7 Activation-induced cytidine deaminase protein 20130415 {GO:0016814=IEA, GO:0006397=IEA, GO:0005515=IPI, GO:0045190=IEA, GO:0005634=IDA, GO:0016445=IDA, GO:0090310=IDA, GO:0000178=IDA, GO:0005737=IDA, GO:0071222=IEA, GO:0030183=NAS, GO:0080111=IDA, GO:0004126=IDA, GO:0008270=IEA} B cell differentiation, DNA demethylation, cellular response to lipopolysaccharide, isotype switching, mRNA processing, negative regulation of methylation-dependent chromatin silencing, somatic diversification of immunoglobulins cytoplasm, exosome (RNase complex), nucleus cytidine deaminase activity, hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines, protein binding, zinc ion binding Human UniProtKB:Q13569 AIDA MGI UniProtKB {GO:0043496=GO_REF:0000024, GO:0044444=GO_REF:0000019, GO:0046329=GO_REF:0000024, GO:0019904=GO_REF:0000019, GO:0005575=GO_REF:0000015, GO:0009953=GO_REF:0000024, GO:0043508=PMID:17681137} Q96BJ3 Axin interactor, dorsalization-associated protein protein 20110406 {GO:0043496=ISS, GO:0044444=IEA, GO:0046329=ISS, GO:0019904=IEA, GO:0005575=ND, GO:0009953=ISS, GO:0043508=IDA} dorsal/ventral pattern formation, negative regulation of JNK cascade, negative regulation of JUN kinase activity, regulation of protein homodimerization activity cellular_component, cytoplasmic part protein domain specific binding Human AIF1 InterPro UniProtKB {GO:2000406=PMID:16049345, GO:1900087=PMID:15117732, GO:0005884=PMID:18699778, GO:0005509=GO_REF:0000002, GO:0032587=PMID:18699778, GO:0001891=GO_REF:0000024, GO:0005634=PMID:22116621, GO:0006911=GO_REF:0000024, GO:0030027=GO_REF:0000024, GO:0005829=PMID:22116621, GO:0003674=GO_REF:0000015, GO:0016601=GO_REF:0000024, GO:0005737=GO_REF:0000024, GO:0051015=PMID:16049345, GO:0006954=GO_REF:0000024, GO:0071346=GO_REF:0000024, GO:0042102=PMID:16049345, GO:0030041=PMID:16049345, GO:0097178=PMID:17011575, GO:0090026=PMID:15117732, GO:0001774=PMID:17011575, GO:0051017=PMID:18699778} Q5STX8 Allograft inflammatory factor 1 protein 20130413 {GO:2000406=IDA, GO:1900087=IDA, GO:0005884=IDA, GO:0005509=IEA, GO:0032587=IDA, GO:0001891=ISS, GO:0005634=IDA, GO:0006911=ISS, GO:0030027=ISS, GO:0005829=IDA, GO:0003674=ND, GO:0016601=ISS, GO:0005737=ISS, GO:0051015=IDA, GO:0006954=ISS, GO:0071346=ISS, GO:0042102=IDA, GO:0030041=IDA, GO:0097178=NAS, GO:0090026=IDA, GO:0001774=NAS, GO:0051017=IDA} Rac protein signal transduction, actin filament bundle assembly, actin filament polymerization, cellular response to interferon-gamma, inflammatory response, microglial cell activation, phagocytosis, engulfment, positive regulation of G1/S transition of mitotic cell cycle, positive regulation of T cell migration, positive regulation of T cell proliferation, positive regulation of monocyte chemotaxis, ruffle assembly actin filament, cytoplasm, cytosol, lamellipodium, nucleus, phagocytic cup, ruffle membrane actin filament binding, calcium ion binding, molecular_function Human InterPro:IPR002048|InterPro:IPR011992 AIF1L LIFEdb UniProtKB {GO:0043234=GO_REF:0000019, GO:0005737=GO_REF:0000037, GO:0051015=PMID:18699778, GO:0005884=PMID:18699778, GO:0005509=GO_REF:0000002, GO:0032587=GO_REF:0000039, GO:0015629=GO_REF:0000054, GO:0005925=GO_REF:0000054} Q9BQI0 Allograft inflammatory factor 1-like protein 20100607 {GO:0043234=IEA, GO:0005737=IEA, GO:0051015=IDA, GO:0005884=IDA, GO:0005509=IEA, GO:0032587=IEA, GO:0015629=IDA, GO:0005925=IDA} actin cytoskeleton, actin filament, cytoplasm, focal adhesion, protein complex, ruffle membrane actin filament binding, calcium ion binding Human AIFM1 IntAct UniProtKB {GO:0005515=PMID:22371500, GO:0048471=GO_REF:0000039, GO:0006919=PMID:17094969, GO:0050660=GO_REF:0000002, GO:0005743=GO_REF:0000039, GO:0009055=PMID:9989411, GO:0005634=GO_REF:0000024, GO:0051402=GO_REF:0000019, GO:0003677=GO_REF:0000037, GO:0005829=GO_REF:0000024, GO:0005739=PMID:9989411, GO:0005758=PMID:15775970, GO:0006309=GO_REF:0000019, GO:0070059=GO_REF:0000024, GO:0016491=GO_REF:0000037, GO:0045454=GO_REF:0000002} O95831 Apoptosis-inducing factor 1, mitochondrial protein 20130415 {GO:0005515=IPI, GO:0048471=IEA, GO:0006919=IDA, GO:0050660=IEA, GO:0005743=IEA, GO:0009055=TAS, GO:0005634=ISS, GO:0051402=IEA, GO:0003677=IEA, GO:0005829=ISS, GO:0005739=TAS, GO:0005758=IDA, GO:0006309=IEA, GO:0070059=ISS, GO:0016491=IEA, GO:0045454=IEA} activation of cysteine-type endopeptidase activity involved in apoptotic process, apoptotic DNA fragmentation, cell redox homeostasis, intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress, neuron apoptotic process cytosol, mitochondrial inner membrane, mitochondrial intermembrane space, mitochondrion, nucleus, perinuclear region of cytoplasm DNA binding, electron carrier activity, flavin adenine dinucleotide binding, oxidoreductase activity, protein binding Human UniProtKB:Q63ZY3-2 AIFM2 MGI UniProtKB {GO:0005739=PMID:11980907, GO:0005737=PMID:12135761, GO:0008637=PMID:11980907, GO:0030261=PMID:11980907, GO:0004174=PMID:15958387, GO:0050660=PMID:15958387, GO:0005741=PMID:11980907, GO:0006917=PMID:11980907, GO:0016021=GO_REF:0000037, GO:0003677=PMID:15958387, GO:0005829=PMID:11980907} Q9BRQ8 Apoptosis-inducing factor 2 protein 20060110 {GO:0005739=IDA, GO:0005737=IDA, GO:0008637=NAS, GO:0030261=IDA, GO:0004174=IDA, GO:0050660=IDA, GO:0005741=IDA, GO:0006917=IDA, GO:0016021=IEA, GO:0003677=IDA, GO:0005829=IDA} apoptotic mitochondrial changes, chromosome condensation, induction of apoptosis cytoplasm, cytosol, integral to membrane, mitochondrial outer membrane, mitochondrion DNA binding, electron-transferring-flavoprotein dehydrogenase activity, flavin adenine dinucleotide binding Human AIFM3 HPA UniProtKB {GO:0008635=PMID:15764604, GO:0005886=PMID:15764604, GO:0051537=GO_REF:0000037, GO:0005783=PMID:15764604, GO:0050660=GO_REF:0000002, GO:0005743=PMID:15764604, GO:0005634=PMID:15764604, GO:0006917=PMID:15764604, GO:0008656=PMID:15764604, GO:0046872=GO_REF:0000037, GO:0051882=PMID:15764604, GO:0005829=PMID:15764604, GO:0005739=GO_REF:0000052, GO:0005737=GO_REF:0000052, GO:0016491=GO_REF:0000037, GO:0045454=GO_REF:0000002, GO:0022900=GO_REF:0000037} Q96NN9 Apoptosis-inducing factor 3 protein 20101115 {GO:0008635=IDA, GO:0005886=IDA, GO:0051537=IEA, GO:0005783=IDA, GO:0050660=IEA, GO:0005743=IDA, GO:0005634=IDA, GO:0006917=IDA, GO:0008656=IDA, GO:0046872=IEA, GO:0051882=IDA, GO:0005829=IDA, GO:0005739=IDA, GO:0005737=IDA, GO:0016491=IEA, GO:0045454=IEA, GO:0022900=IEA} activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c, cell redox homeostasis, electron transport chain, induction of apoptosis, mitochondrial depolarization cytoplasm, cytosol, endoplasmic reticulum, mitochondrial inner membrane, mitochondrion, nucleus, plasma membrane 2 iron, 2 sulfur cluster binding, cysteine-type endopeptidase activator activity involved in apoptotic process, flavin adenine dinucleotide binding, metal ion binding, oxidoreductase activity Human AIG1 IntAct UniProtKB {GO:0005515=PMID:21988832, GO:0016021=GO_REF:0000037} Q9NVV5 Androgen-induced gene 1 protein protein 20130415 {GO:0005515=IPI, GO:0016021=IEA} integral to membrane protein binding Human UniProtKB:Q96PM5 AIM1 UniProtKB UniProtKB {GO:0008150=GO_REF:0000015, GO:0003674=GO_REF:0000015, GO:0005575=GO_REF:0000015} Q9Y4K1 Absent in melanoma 1 protein protein 20061026 {GO:0008150=ND, GO:0003674=ND, GO:0005575=ND} biological_process cellular_component molecular_function Human AIM1L null null {} null null null null {} null null null AIM2 HPA UniProtKB {GO:0005515=PMID:22286270, GO:2001056=GO_REF:0000019, GO:0035458=GO_REF:0000019, GO:0032731=GO_REF:0000019, GO:0005634=GO_REF:0000052, GO:0002218=GO_REF:0000019, GO:0035872=Reactome:REACT_75913, GO:0005829=Reactome:REACT_75821, GO:0042802=GO_REF:0000019, GO:0005739=GO_REF:0000052, GO:0005737=PMID:19158679, GO:0006955=PMID:9242382, GO:0003690=GO_REF:0000019, GO:0051092=PMID:19158675, GO:0006954=GO_REF:0000037, GO:0050718=PMID:19158679, GO:0032461=PMID:19158676, GO:0050702=PMID:19158679, GO:0005730=GO_REF:0000052, GO:0006915=GO_REF:0000037, GO:0032088=PMID:16432157, GO:0035690=PMID:19158679, GO:0070269=GO_REF:0000019, GO:0033209=PMID:16432157, GO:0044444=PMID:19158679, GO:0002230=GO_REF:0000019, GO:0045087=Reactome:REACT_6802, GO:0097169=PMID:19158676} Q5T3W0 Interferon-inducible protein AIM2 protein 20101115 {GO:0005515=IPI, GO:2001056=IEA, GO:0035458=IEA, GO:0032731=IEA, GO:0005634=IDA, GO:0002218=IEA, GO:0035872=TAS, GO:0005829=TAS, GO:0042802=IEA, GO:0005739=IDA, GO:0005737=IDA, GO:0006955=TAS, GO:0003690=IEA, GO:0051092=IDA, GO:0006954=IEA, GO:0050718=IDA, GO:0032461=IDA, GO:0050702=IMP, GO:0005730=IDA, GO:0006915=IEA, GO:0032088=IDA, GO:0035690=IDA, GO:0070269=IEA, GO:0033209=IDA, GO:0044444=IDA, GO:0002230=IEA, GO:0045087=TAS, GO:0097169=IDA} activation of innate immune response, apoptotic process, cellular response to drug, cellular response to interferon-beta, immune response, inflammatory response, innate immune response, interleukin-1 beta secretion, negative regulation of NF-kappaB transcription factor activity, nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway, positive regulation of NF-kappaB transcription factor activity, positive regulation of cysteine-type endopeptidase activity, positive regulation of defense response to virus by host, positive regulation of interleukin-1 beta production, positive regulation of interleukin-1 beta secretion, positive regulation of protein oligomerization, pyroptosis, tumor necrosis factor-mediated signaling pathway AIM2 inflammasome complex, cytoplasm, cytoplasmic part, cytosol, mitochondrion, nucleolus, nucleus double-stranded DNA binding, identical protein binding, protein binding Human AIMP1 IntAct UniProtKB {GO:0030133=GO_REF:0000039, GO:0005515=PMID:22190034, GO:0010467=Reactome:REACT_71, GO:0043498=PMID:11741979, GO:0005783=GO_REF:0000039, GO:0007267=PMID:11741979, GO:0005634=GO_REF:0000039, GO:0050900=PMID:11306575, GO:0005615=GO_REF:0000037, GO:0017101=PMID:14500886, GO:0042803=PMID:11306575, GO:0005829=Reactome:REACT_15516, GO:0006954=GO_REF:0000037, GO:0006935=PMID:7545917, GO:0006006=GO_REF:0000037, GO:0007155=GO_REF:0000037, GO:0005794=GO_REF:0000039, GO:0000049=PMID:11306575, GO:0009611=PMID:7545917, GO:0006915=GO_REF:0000037, GO:0001525=GO_REF:0000037, GO:0005125=PMID:11306575, GO:0006418=Reactome:REACT_15482, GO:0007165=PMID:9405472, GO:0001937=PMID:11741979} Q12904 Aminoacyl tRNA synthase complex-interacting multifunctional protein 1 protein 20130415 {GO:0030133=IEA, GO:0005515=IPI, GO:0010467=TAS, GO:0043498=IDA, GO:0005783=IEA, GO:0007267=IDA, GO:0005634=IEA, GO:0050900=IDA, GO:0005615=IEA, GO:0017101=IDA, GO:0042803=IDA, GO:0005829=TAS, GO:0006954=IEA, GO:0006935=TAS, GO:0006006=IEA, GO:0007155=IEA, GO:0005794=IEA, GO:0000049=IDA, GO:0009611=TAS, GO:0006915=IEA, GO:0001525=IEA, GO:0005125=ISS, GO:0006418=TAS, GO:0007165=NAS, GO:0001937=IDA} angiogenesis, apoptotic process, cell adhesion, cell-cell signaling, chemotaxis, gene expression, glucose metabolic process, inflammatory response, leukocyte migration, negative regulation of endothelial cell proliferation, response to wounding, signal transduction, tRNA aminoacylation for protein translation Golgi apparatus, aminoacyl-tRNA synthetase multienzyme complex, cytosol, endoplasmic reticulum, extracellular space, nucleus, transport vesicle cell surface binding, cytokine activity, protein binding, protein homodimerization activity, tRNA binding Human UniProtKB:P04591:PRO_0000038593 AIMP2 IntAct UniProtKB {GO:0005515=PMID:22190034, GO:0010467=Reactome:REACT_71, GO:0008285=GO_REF:0000019, GO:0031398=GO_REF:0000019, GO:0006915=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0060510=GO_REF:0000019, GO:0006418=Reactome:REACT_15482, GO:0005829=Reactome:REACT_15516} Q13155 Aminoacyl tRNA synthase complex-interacting multifunctional protein 2 protein 20130415 {GO:0005515=IPI, GO:0010467=TAS, GO:0008285=IEA, GO:0031398=IEA, GO:0006915=IEA, GO:0005634=IEA, GO:0060510=IEA, GO:0006418=TAS, GO:0005829=TAS} Type II pneumocyte differentiation, apoptotic process, gene expression, negative regulation of cell proliferation, positive regulation of protein ubiquitination, tRNA aminoacylation for protein translation cytosol, nucleus protein binding Human UniProtKB:P04591:PRO_0000038593 AIP GOC UniProtKB {GO:0005515=PMID:21903422, GO:0006805=GO_REF:0000019, GO:0005886=PMID:17329248, GO:0006626=PMID:14557246, GO:0051344=GO_REF:0000019, GO:0003713=PMID:9447995, GO:0003755=GO_REF:0000038, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0010738=GO_REF:0000019, GO:0022417=PMID:14557246, GO:0005829=PMID:14557246, GO:0044445=GO_REF:0000019, GO:0007165=PMID:9111057, GO:0005737=GO_REF:0000052, GO:0006457=GO_REF:0000038, GO:0051082=PMID:14557246, GO:0004871=PMID:9111057, GO:0036004=PMID:17329248, GO:0008134=PMID:9447995} O00170 AH receptor-interacting protein protein 20130413 {GO:0005515=IPI, GO:0006805=IEA, GO:0005886=IDA, GO:0006626=IDA, GO:0051344=IEA, GO:0003713=TAS, GO:0003755=IEA, GO:0005730=IDA, GO:0005634=IDA, GO:0010738=IEA, GO:0022417=IDA, GO:0005829=TAS, GO:0044445=IEA, GO:0007165=TAS, GO:0005737=IDA, GO:0006457=IEA, GO:0051082=IDA, GO:0004871=TAS, GO:0036004=IDA, GO:0008134=TAS} negative regulation of cyclic-nucleotide phosphodiesterase activity, protein folding, protein maturation by protein folding, protein targeting to mitochondrion, regulation of protein kinase A signaling cascade, signal transduction, xenobiotic metabolic process cytoplasm, cytosol, cytosolic part, nucleolus, nucleus, plasma membrane GAF domain binding, peptidyl-prolyl cis-trans isomerase activity, protein binding, signal transducer activity, transcription coactivator activity, transcription factor binding, unfolded protein binding Human AIPL1 MGI UniProtKB {GO:0018343=PMID:14555765, GO:0001918=PMID:14555765, GO:0001917=GO_REF:0000019, GO:0005737=PMID:12374762, GO:0043066=GO_REF:0000019, GO:0007603=GO_REF:0000019, GO:0001895=GO_REF:0000019, GO:0006457=GO_REF:0000002, GO:0005634=PMID:12374762, GO:0051082=PMID:10615133, GO:0007601=GO_REF:0000037, GO:0030823=GO_REF:0000019} Q9NZN9 Aryl-hydrocarbon-interacting protein-like 1 protein 20101102 {GO:0018343=IDA, GO:0001918=IDA, GO:0001917=IEA, GO:0005737=IDA, GO:0043066=IEA, GO:0007603=IEA, GO:0001895=IEA, GO:0006457=IEA, GO:0005634=IDA, GO:0051082=TAS, GO:0007601=IEA, GO:0030823=IEA} negative regulation of apoptotic process, phototransduction, visible light, protein farnesylation, protein folding, regulation of cGMP metabolic process, retina homeostasis, visual perception cytoplasm, nucleus, photoreceptor inner segment farnesylated protein binding, unfolded protein binding Human AIRE HPA UniProtKB {GO:0005515=PMID:20085707, GO:0006355=PMID:18292755, GO:0005886=GO_REF:0000052, GO:0044212=PMID:18292755, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0015629=GO_REF:0000052, GO:0045182=GO_REF:0000002, GO:0006351=GO_REF:0000037, GO:0042802=GO_REF:0000019, GO:0042393=PMID:18292755, GO:0005737=GO_REF:0000052, GO:0006955=PMID:9398840, GO:0045944=GO_REF:0000019, GO:0003682=PMID:18292755, GO:0006959=GO_REF:0000019, GO:0008270=PMID:19446523, GO:0045893=PMID:18292755} O43918 Autoimmune regulator protein 20110516 {GO:0005515=IPI, GO:0006355=IDA, GO:0005886=IDA, GO:0044212=IDA, GO:0005730=IDA, GO:0005634=IDA, GO:0015629=IDA, GO:0045182=IEA, GO:0006351=IEA, GO:0042802=IEA, GO:0042393=IDA, GO:0005737=IDA, GO:0006955=TAS, GO:0045944=IEA, GO:0003682=IDA, GO:0006959=IEA, GO:0008270=IDA, GO:0045893=IDA} humoral immune response, immune response, positive regulation of transcription from RNA polymerase II promoter, positive regulation of transcription, DNA-dependent, regulation of transcription, DNA-dependent, transcription, DNA-dependent actin cytoskeleton, cytoplasm, nucleolus, nucleus, plasma membrane chromatin binding, histone binding, identical protein binding, protein binding, transcription regulatory region DNA binding, translation regulator activity, zinc ion binding Human AJAP1 UniProtKB UniProtKB {GO:0016323=GO_REF:0000039, GO:0016324=GO_REF:0000039, GO:0005912=GO_REF:0000039, GO:0016021=GO_REF:0000037, GO:0007155=GO_REF:0000037} Q9UKB5 Adherens junction-associated protein 1 protein 20130413 {GO:0016323=IEA, GO:0016324=IEA, GO:0005912=IEA, GO:0016021=IEA, GO:0007155=IEA} cell adhesion adherens junction, apical plasma membrane, basolateral plasma membrane, integral to membrane Human UniProtKB-SubCell:SL-0015 AJUBA MGI UniProtKB {GO:0005515=PMID:18805794, GO:0035313=GO_REF:0000019, GO:0005886=GO_REF:0000039, GO:0030032=GO_REF:0000019, GO:2000637=PMID:20616046, GO:0005634=PMID:18805794, GO:0005829=GO_REF:0000019, GO:0016339=GO_REF:0000019, GO:0031334=PMID:15870274, GO:0051015=GO_REF:0000019, GO:0000932=PMID:20616046, GO:0005911=PMID:12417594, GO:0043406=GO_REF:0000019, GO:0048041=GO_REF:0000019, GO:0043123=GO_REF:0000019, GO:0030334=GO_REF:0000019, GO:0033673=GO_REF:0000019, GO:0001666=PMID:22286099, GO:0005667=GO_REF:0000019, GO:0005815=GO_REF:0000039, GO:0045294=PMID:12417594, GO:0003714=PMID:18805794, GO:0000122=GO_REF:0000019, GO:0030027=GO_REF:0000019, GO:0043087=GO_REF:0000019, GO:0006351=GO_REF:0000037, GO:0035331=PMID:20303269, GO:1900037=PMID:22286099, GO:0007049=GO_REF:0000037, GO:0035195=PMID:20616046, GO:0003682=GO_REF:0000019, GO:0008270=GO_REF:0000002, GO:0034613=GO_REF:0000019, GO:0031328=GO_REF:0000019, GO:0005925=GO_REF:0000019, GO:0046474=GO_REF:0000019} Q96IF1 LIM domain-containing protein ajuba protein 20110107 {GO:0005515=IPI, GO:0035313=IEA, GO:0005886=IEA, GO:0030032=IEA, GO:2000637=IMP, GO:0005634=IDA, GO:0005829=IEA, GO:0016339=IEA, GO:0031334=IDA, GO:0051015=IEA, GO:0000932=IDA, GO:0005911=IDA, GO:0043406=IEA, GO:0048041=IEA, GO:0043123=IEA, GO:0030334=IEA, GO:0033673=IEA, GO:0001666=IDA, GO:0005667=IEA, GO:0005815=IEA, GO:0045294=IDA, GO:0003714=IDA, GO:0000122=IEA, GO:0030027=IEA, GO:0043087=IEA, GO:0006351=IEA, GO:0035331=IDA, GO:1900037=IDA, GO:0007049=IEA, GO:0035195=IMP, GO:0003682=IEA, GO:0008270=IEA, GO:0034613=IEA, GO:0031328=IEA, GO:0005925=IEA, GO:0046474=IEA} calcium-dependent cell-cell adhesion, cell cycle, cellular protein localization, focal adhesion assembly, gene silencing by miRNA, glycerophospholipid biosynthetic process, lamellipodium assembly, negative regulation of hippo signaling cascade, negative regulation of kinase activity, negative regulation of transcription from RNA polymerase II promoter, positive regulation of I-kappaB kinase/NF-kappaB cascade, positive regulation of MAP kinase activity, positive regulation of cellular biosynthetic process, positive regulation of gene silencing by miRNA, positive regulation of protein complex assembly, regulation of GTPase activity, regulation of cell migration, regulation of cellular response to hypoxia, response to hypoxia, transcription, DNA-dependent, wound healing, spreading of epidermal cells cell-cell junction, cytoplasmic mRNA processing body, cytosol, focal adhesion, lamellipodium, microtubule organizing center, nucleus, plasma membrane, transcription factor complex actin filament binding, alpha-catenin binding, chromatin binding, protein binding, transcription corepressor activity, zinc ion binding Human AK1 HPA UniProtKB {GO:0046034=GO_REF:0000002, GO:0015949=Reactome:REACT_21330, GO:0005886=GO_REF:0000019, GO:0055086=Reactome:REACT_1698, GO:0036126=GO_REF:0000019, GO:0004017=GO_REF:0000002, GO:0044281=Reactome:REACT_111217, GO:0005524=GO_REF:0000002, GO:0001520=GO_REF:0000019, GO:0019205=GO_REF:0000002, GO:0005829=Reactome:REACT_763, GO:0006139=GO_REF:0000002, GO:0005737=GO_REF:0000052, GO:0007050=GO_REF:0000019} Q5T9B7 Adenylate kinase isoenzyme 1 protein 20101115 {GO:0046034=IEA, GO:0015949=TAS, GO:0005886=IEA, GO:0055086=TAS, GO:0036126=IEA, GO:0004017=IEA, GO:0044281=TAS, GO:0005524=IEA, GO:0001520=IEA, GO:0019205=IEA, GO:0005829=TAS, GO:0006139=IEA, GO:0005737=IDA, GO:0007050=IEA} ATP metabolic process, cell cycle arrest, nucleobase-containing compound metabolic process, nucleobase-containing small molecule interconversion, nucleobase-containing small molecule metabolic process, small molecule metabolic process cytoplasm, cytosol, outer dense fiber, plasma membrane, sperm flagellum ATP binding, adenylate kinase activity, nucleobase-containing compound kinase activity Human AK2 Reactome UniProtKB {GO:0046033=GO_REF:0000019, GO:0015949=Reactome:REACT_21330, GO:0097066=GO_REF:0000019, GO:0046060=GO_REF:0000019, GO:0046034=GO_REF:0000019, GO:0097226=GO_REF:0000019, GO:0005743=GO_REF:0000019, GO:0055086=Reactome:REACT_1698, GO:0044281=Reactome:REACT_111217, GO:0004017=GO_REF:0000003, GO:0005524=GO_REF:0000037, GO:0005829=GO_REF:0000019, GO:0006119=GO_REF:0000019, GO:0019205=GO_REF:0000002, GO:0001889=GO_REF:0000019, GO:0005758=Reactome:REACT_2031, GO:0006139=GO_REF:0000002, GO:0007420=GO_REF:0000019, GO:0006172=GO_REF:0000019} P54819 Adenylate kinase 2, mitochondrial protein 20130301 {GO:0046033=IEA, GO:0015949=TAS, GO:0097066=IEA, GO:0046060=IEA, GO:0046034=IEA, GO:0097226=IEA, GO:0005743=IEA, GO:0055086=TAS, GO:0044281=TAS, GO:0004017=IEA, GO:0005524=IEA, GO:0005829=IEA, GO:0006119=IEA, GO:0019205=IEA, GO:0001889=IEA, GO:0005758=TAS, GO:0006139=IEA, GO:0007420=IEA, GO:0006172=IEA} ADP biosynthetic process, AMP metabolic process, ATP metabolic process, brain development, dATP metabolic process, liver development, nucleobase-containing compound metabolic process, nucleobase-containing small molecule interconversion, nucleobase-containing small molecule metabolic process, oxidative phosphorylation, response to thyroid hormone stimulus, small molecule metabolic process cytosol, mitochondrial inner membrane, mitochondrial intermembrane space, sperm mitochondrial sheath ATP binding, adenylate kinase activity, nucleobase-containing compound kinase activity Human AK3 BHF-UCL UniProtKB {GO:0005739=GO_REF:0000024, GO:0046041=PMID:11485571, GO:0046033=PMID:11485571, GO:0046051=PMID:11485571, GO:0007596=Reactome:REACT_604, GO:0005759=PMID:11485571, GO:0046039=PMID:11485571, GO:0004017=PMID:11485571, GO:0005525=GO_REF:0000037, GO:0046899=PMID:11485571, GO:0005524=GO_REF:0000002} Q9UIJ7 GTP:AMP phosphotransferase AK3, mitochondrial protein 20120528 {GO:0005739=ISS, GO:0046041=IDA, GO:0046033=IDA, GO:0046051=IDA, GO:0007596=TAS, GO:0005759=ISS, GO:0046039=IDA, GO:0004017=IDA, GO:0005525=IEA, GO:0046899=IDA, GO:0005524=IEA} AMP metabolic process, GTP metabolic process, ITP metabolic process, UTP metabolic process, blood coagulation mitochondrial matrix, mitochondrion ATP binding, GTP binding, adenylate kinase activity, nucleoside triphosphate adenylate kinase activity Human AK4 BHF-UCL UniProtKB {GO:0046033=PMID:19766732, GO:0046034=PMID:19766732, GO:0042493=GO_REF:0000019, GO:0043643=GO_REF:0000019, GO:0004017=PMID:19766732, GO:0005525=GO_REF:0000037, GO:0005524=GO_REF:0000037, GO:0046899=PMID:19766732, GO:0005739=PMID:19766732, GO:0001889=GO_REF:0000019, GO:0007420=GO_REF:0000019, GO:0005759=PMID:11485571, GO:0018885=GO_REF:0000019, GO:0046039=PMID:19766732} P27144 GTP:AMP phosphotransferase AK4, mitochondrial protein 20120528 {GO:0046033=IDA, GO:0046034=IDA, GO:0042493=IEA, GO:0043643=IEA, GO:0004017=IDA, GO:0005525=IEA, GO:0005524=IEA, GO:0046899=IDA, GO:0005739=IDA, GO:0001889=IEA, GO:0007420=IEA, GO:0005759=ISS, GO:0018885=IEA, GO:0046039=IDA} AMP metabolic process, ATP metabolic process, GTP metabolic process, brain development, carbon tetrachloride metabolic process, liver development, response to drug, tetracycline metabolic process mitochondrial matrix, mitochondrion ATP binding, GTP binding, adenylate kinase activity, nucleoside triphosphate adenylate kinase activity Human AK5 HPA UniProtKB {GO:0005813=GO_REF:0000052, GO:0046034=GO_REF:0000002, GO:0015949=Reactome:REACT_21330, GO:0008603=GO_REF:0000002, GO:0009220=PMID:10215863, GO:0055086=Reactome:REACT_1698, GO:0044281=Reactome:REACT_111217, GO:0004017=GO_REF:0000003, GO:0019206=Reactome:REACT_1716, GO:0005524=GO_REF:0000037, GO:0019205=GO_REF:0000002, GO:0005829=Reactome:REACT_1716, GO:0007165=GO_REF:0000002, GO:0005737=GO_REF:0000052, GO:0006139=GO_REF:0000002, GO:0006172=PMID:10215863, GO:0006173=PMID:10215863} Q9Y6K8 Adenylate kinase isoenzyme 5 protein 20100326 {GO:0005813=IDA, GO:0046034=IEA, GO:0015949=TAS, GO:0008603=IEA, GO:0009220=TAS, GO:0055086=TAS, GO:0044281=TAS, GO:0004017=IEA, GO:0019206=EXP, GO:0005524=IEA, GO:0019205=IEA, GO:0005829=TAS, GO:0007165=IEA, GO:0005737=IDA, GO:0006139=IEA, GO:0006172=TAS, GO:0006173=TAS} ADP biosynthetic process, ATP metabolic process, dADP biosynthetic process, nucleobase-containing compound metabolic process, nucleobase-containing small molecule interconversion, nucleobase-containing small molecule metabolic process, pyrimidine ribonucleotide biosynthetic process, signal transduction, small molecule metabolic process centrosome, cytoplasm, cytosol ATP binding, adenylate kinase activity, cAMP-dependent protein kinase regulator activity, nucleobase-containing compound kinase activity, nucleoside kinase activity Human AK7 UniProtKB UniProtKB {GO:0002437=GO_REF:0000019, GO:0035083=GO_REF:0000019, GO:0003351=GO_REF:0000019, GO:0007420=GO_REF:0000019, GO:0004127=PMID:21080915, GO:0007283=GO_REF:0000019, GO:0004017=PMID:21080915, GO:0005524=GO_REF:0000037, GO:0005829=GO_REF:0000039} Q96M32 Adenylate kinase 7 protein 20110120 {GO:0002437=IEA, GO:0035083=IEA, GO:0003351=IEA, GO:0007420=IEA, GO:0004127=IDA, GO:0007283=IEA, GO:0004017=IDA, GO:0005524=IEA, GO:0005829=IEA} brain development, cilium axoneme assembly, epithelial cilium movement, inflammatory response to antigenic stimulus, spermatogenesis cytosol ATP binding, adenylate kinase activity, cytidylate kinase activity Human AKAP1 HPA UniProtKB {GO:0005739=GO_REF:0000052, GO:0007596=Reactome:REACT_604, GO:0003723=GO_REF:0000037, GO:0005741=GO_REF:0000039, GO:0016021=GO_REF:0000037, GO:0005829=Reactome:REACT_24992} Q92667 A-kinase anchor protein 1, mitochondrial protein 20101115 {GO:0005739=IDA, GO:0007596=TAS, GO:0003723=IEA, GO:0005741=IEA, GO:0016021=IEA, GO:0005829=TAS} blood coagulation cytosol, integral to membrane, mitochondrial outer membrane, mitochondrion RNA binding Human AKAP10 HPA UniProtKB {GO:0005739=GO_REF:0000039, GO:0007165=PMID:9326583, GO:0005737=GO_REF:0000052, GO:0008104=GO_REF:0000019, GO:0005886=GO_REF:0000052, GO:0007596=Reactome:REACT_604, GO:0038032=GO_REF:0000002, GO:0005829=Reactome:REACT_24992} O43572 A-kinase anchor protein 10, mitochondrial protein 20101115 {GO:0005739=IEA, GO:0007165=TAS, GO:0005737=IDA, GO:0008104=IEA, GO:0005886=IDA, GO:0007596=TAS, GO:0038032=IEA, GO:0005829=TAS} blood coagulation, protein localization, signal transduction, termination of G-protein coupled receptor signaling pathway cytoplasm, cytosol, mitochondrion, plasma membrane Human AKAP11 HPA UniProtKB {GO:0005737=GO_REF:0000052, GO:0005886=GO_REF:0000052, GO:0005815=GO_REF:0000039, GO:0005730=GO_REF:0000052, GO:0008157=PMID:10209101, GO:0051018=PMID:10209101, GO:0007243=PMID:10209101} Q9UKA4 A-kinase anchor protein 11 protein 20111111 {GO:0005737=IDA, GO:0005886=IDA, GO:0005815=IEA, GO:0005730=IDA, GO:0008157=TAS, GO:0051018=TAS, GO:0007243=TAS} intracellular protein kinase cascade cytoplasm, microtubule organizing center, nucleolus, plasma membrane protein kinase A binding, protein phosphatase 1 binding Human AKAP12 HPA UniProtKB {GO:0005515=PMID:20029029, GO:0005737=GO_REF:0000052, GO:0005886=GO_REF:0000052, GO:0007186=PMID:10858453, GO:0008179=PMID:17081159, GO:0030819=PMID:17081159, GO:0006605=GO_REF:0000002, GO:0051018=PMID:10858453, GO:0005856=GO_REF:0000039, GO:0010739=PMID:17081159, GO:0005938=GO_REF:0000039} Q02952 A-kinase anchor protein 12 protein 20080205 {GO:0005515=IPI, GO:0005737=IDA, GO:0005886=IDA, GO:0007186=TAS, GO:0008179=IPI, GO:0030819=IMP, GO:0006605=IEA, GO:0051018=TAS, GO:0005856=IEA, GO:0010739=IMP, GO:0005938=IEA} G-protein coupled receptor signaling pathway, positive regulation of cAMP biosynthetic process, positive regulation of protein kinase A signaling cascade, protein targeting cell cortex, cytoplasm, cytoskeleton, plasma membrane adenylate cyclase binding, protein binding, protein kinase A binding Human AKAP13 HPA UniProtKB {GO:0005515=PMID:9627117, GO:0051056=Reactome:REACT_11051, GO:0048011=Reactome:REACT_13776, GO:0007264=Reactome:REACT_11044, GO:0035023=GO_REF:0000002, GO:0006915=Reactome:REACT_13638, GO:0005634=GO_REF:0000039, GO:0097190=Reactome:REACT_13720, GO:0046872=GO_REF:0000037, GO:0005829=Reactome:REACT_19216, GO:0035556=GO_REF:0000002, GO:0005737=GO_REF:0000052, GO:0005543=GO_REF:0000002, GO:0016020=GO_REF:0000039, GO:0016301=GO_REF:0000038, GO:1900169=GO_REF:0000019, GO:0004871=PMID:8290273, GO:0005089=GO_REF:0000002, GO:0004691=PMID:1618839} Q12802 A-kinase anchor protein 13 protein 20100326 {GO:0005515=IPI, GO:0051056=TAS, GO:0048011=TAS, GO:0007264=TAS, GO:0035023=IEA, GO:0006915=TAS, GO:0005634=IEA, GO:0097190=TAS, GO:0046872=IEA, GO:0005829=TAS, GO:0035556=IEA, GO:0005737=IDA, GO:0005543=IEA, GO:0016020=IEA, GO:0016301=IEA, GO:1900169=IEA, GO:0004871=TAS, GO:0005089=IEA, GO:0004691=NAS} apoptotic process, apoptotic signaling pathway, intracellular signal transduction, neurotrophin TRK receptor signaling pathway, regulation of Rho protein signal transduction, regulation of glucocorticoid mediated signaling pathway, regulation of small GTPase mediated signal transduction, small GTPase mediated signal transduction cytoplasm, cytosol, membrane, nucleus Rho guanyl-nucleotide exchange factor activity, cAMP-dependent protein kinase activity, kinase activity, metal ion binding, phospholipid binding, protein binding, signal transducer activity Human AKAP14 UniProtKB UniProtKB {GO:0005737=GO_REF:0000039, GO:0007283=GO_REF:0000019, GO:0051018=GO_REF:0000019} Q86UN6 A-kinase anchor protein 14 protein 20130413 {GO:0005737=IEA, GO:0007283=IEA, GO:0051018=IEA} spermatogenesis cytoplasm protein kinase A binding Human UniProtKB-SubCell:SL-0086 AKAP17A UniProtKB UniProtKB {GO:0008380=GO_REF:0000037, GO:0006397=GO_REF:0000037, GO:0007165=PMID:1438229, GO:0042113=PMID:1438229, GO:0006355=PMID:1438229, GO:0016607=PMID:16982639, GO:0000166=GO_REF:0000002, GO:0003723=GO_REF:0000037, GO:0005634=PMID:19840947, GO:0043484=PMID:19840947, GO:0005681=GO_REF:0000037, GO:0051018=PMID:19840947} Q02040 A-kinase anchor protein 17A protein 20111206 {GO:0008380=IEA, GO:0006397=IEA, GO:0007165=NAS, GO:0042113=NAS, GO:0006355=NAS, GO:0016607=IDA, GO:0000166=IEA, GO:0003723=IEA, GO:0005634=IDA, GO:0043484=IMP, GO:0005681=IEA, GO:0051018=IDA} B cell activation, RNA splicing, mRNA processing, regulation of RNA splicing, regulation of transcription, DNA-dependent, signal transduction nuclear speck, nucleus, spliceosomal complex RNA binding, nucleotide binding, protein kinase A binding Human AKAP2 UniProtKB UniProtKB {GO:0019899=GO_REF:0000029} Q9Y2D5 A-kinase anchor protein 2 protein 20040301 {GO:0019899=NAS} enzyme binding Human AKAP3 BHF-UCL UniProtKB {GO:0005515=PMID:18421703, GO:0007338=PMID:10334916, GO:0008104=GO_REF:0000019, GO:0001669=GO_REF:0000039, GO:0007178=GO_REF:0000019, GO:0006928=GO_REF:0000019, GO:0007340=PMID:10319321, GO:0051018=GO_REF:0000019} O75969 A-kinase anchor protein 3 protein 20110221 {GO:0005515=IPI, GO:0007338=TAS, GO:0008104=IEA, GO:0001669=IEA, GO:0007178=IEA, GO:0006928=IEA, GO:0007340=TAS, GO:0051018=IEA} acrosome reaction, cellular component movement, protein localization, single fertilization, transmembrane receptor protein serine/threonine kinase signaling pathway acrosomal vesicle protein binding, protein kinase A binding Human UniProtKB:Q96C74 AKAP4 PINC UniProtKB {GO:0030018=GO_REF:0000019, GO:0048471=GO_REF:0000019, GO:0005952=PMID:9822690, GO:0031514=PMID:9822690, GO:0006928=PMID:9822690, GO:0097228=GO_REF:0000019, GO:0030317=PMID:9822690, GO:0007338=PMID:9822690, GO:0007165=PMID:9822690, GO:0008104=GO_REF:0000019, GO:0030030=GO_REF:0000037, GO:0007178=GO_REF:0000019, GO:0051018=GO_REF:0000024, GO:0005856=PMID:9822690} Q5JQC9 A-kinase anchor protein 4 protein 20061106 {GO:0030018=IEA, GO:0048471=IEA, GO:0005952=NAS, GO:0031514=IDA, GO:0006928=TAS, GO:0097228=IEA, GO:0030317=IMP, GO:0007338=TAS, GO:0007165=TAS, GO:0008104=IEA, GO:0030030=IEA, GO:0007178=IEA, GO:0051018=ISS, GO:0005856=TAS} cell projection organization, cellular component movement, protein localization, signal transduction, single fertilization, sperm motility, transmembrane receptor protein serine/threonine kinase signaling pathway Z disc, cAMP-dependent protein kinase complex, cytoskeleton, motile cilium, perinuclear region of cytoplasm, sperm principal piece protein kinase A binding Human AKAP5 IntAct UniProtKB {GO:0005515=PMID:11287423, GO:0005516=GO_REF:0000037, GO:0005886=Reactome:REACT_18393, GO:0008179=PMID:17081159, GO:0030819=PMID:17081159, GO:0007268=Reactome:REACT_13685, GO:0006605=GO_REF:0000002, GO:0044281=Reactome:REACT_111217, GO:0010739=PMID:17081159, GO:0005829=Reactome:REACT_18393, GO:0007165=GO_REF:0000002, GO:0006112=Reactome:REACT_1505, GO:0050796=Reactome:REACT_18325, GO:0051018=PMID:1512224} P24588 A-kinase anchor protein 5 protein 20130415 {GO:0005515=IPI, GO:0005516=IEA, GO:0005886=TAS, GO:0008179=IPI, GO:0030819=IMP, GO:0007268=TAS, GO:0006605=IEA, GO:0044281=TAS, GO:0010739=IMP, GO:0005829=TAS, GO:0007165=IEA, GO:0006112=TAS, GO:0050796=TAS, GO:0051018=TAS} energy reserve metabolic process, positive regulation of cAMP biosynthetic process, positive regulation of protein kinase A signaling cascade, protein targeting, regulation of insulin secretion, signal transduction, small molecule metabolic process, synaptic transmission cytosol, plasma membrane adenylate cyclase binding, calmodulin binding, protein binding, protein kinase A binding Human UniProtKB:P35561 AKAP6 BHF-UCL UniProtKB {GO:0005515=PMID:17923693, GO:0031965=GO_REF:0000039, GO:0016529=PMID:10830164, GO:0005102=PMID:10830164, GO:0034704=PMID:10830164, GO:0006605=PMID:10413680, GO:0005635=PMID:10413680, GO:0051018=PMID:10830164} Q13023 A-kinase anchor protein 6 protein 20090226 {GO:0005515=IPI, GO:0031965=IEA, GO:0016529=IDA, GO:0005102=IPI, GO:0034704=IDA, GO:0006605=NAS, GO:0005635=IDA, GO:0051018=TAS} protein targeting calcium channel complex, nuclear envelope, nuclear membrane, sarcoplasmic reticulum protein binding, protein kinase A binding, receptor binding Human UniProtKB:Q92736 AKAP7 UniProtKB UniProtKB {GO:0005515=PMID:17244820, GO:0034237=GO_REF:0000019, GO:0005886=PMID:10613906, GO:0010738=GO_REF:0000019, GO:0005634=GO_REF:0000039, GO:0003824=GO_REF:0000002, GO:0005829=PMID:10613906, GO:0005622=GO_REF:0000002, GO:0035556=PMID:10613906, GO:0016324=GO_REF:0000019, GO:0008104=PMID:9545239, GO:0051018=PMID:10613906, GO:0006811=PMID:9545239, GO:0019901=GO_REF:0000019, GO:0016208=GO_REF:0000019, GO:0016070=GO_REF:0000002, GO:0019904=GO_REF:0000019, GO:0030315=GO_REF:0000019, GO:0008022=GO_REF:0000019, GO:0016328=PMID:10613906, GO:0043234=GO_REF:0000019, GO:0008150=GO_REF:0000015, GO:0032947=GO_REF:0000019, GO:0016529=GO_REF:0000019, GO:0070382=GO_REF:0000019} Q9P0M2 A-kinase anchor protein 7 isoform gamma protein 20120817 {GO:0005515=IPI, GO:0034237=IEA, GO:0005886=TAS, GO:0010738=IEA, GO:0005634=IEA, GO:0003824=IEA, GO:0005829=IDA, GO:0005622=IEA, GO:0035556=TAS, GO:0016324=IEA, GO:0008104=IC, GO:0051018=IDA, GO:0006811=TAS, GO:0019901=IEA, GO:0016208=IEA, GO:0016070=IEA, GO:0019904=IEA, GO:0030315=IEA, GO:0008022=IEA, GO:0016328=IDA, GO:0043234=IEA, GO:0008150=ND, GO:0032947=IEA, GO:0016529=IEA, GO:0070382=IEA} RNA metabolic process, biological_process, intracellular signal transduction, ion transport, protein localization, regulation of protein kinase A signaling cascade T-tubule, apical plasma membrane, cytosol, exocytic vesicle, intracellular, lateral plasma membrane, nucleus, plasma membrane, protein complex, sarcoplasmic reticulum AMP binding, catalytic activity, protein C-terminus binding, protein binding, protein complex scaffold, protein domain specific binding, protein kinase A binding, protein kinase A regulatory subunit binding, protein kinase binding Human UniProtKB:P17252 AKAP8 HPA UniProtKB {GO:0000793=GO_REF:0000019, GO:0007076=GO_REF:0000019, GO:0034237=GO_REF:0000019, GO:0005794=GO_REF:0000019, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0003677=GO_REF:0000002, GO:0016363=GO_REF:0000024, GO:0005739=GO_REF:0000019, GO:0007165=PMID:9473338, GO:0007067=PMID:9473338, GO:0001939=GO_REF:0000019, GO:0003690=GO_REF:0000019, GO:0016020=GO_REF:0000002, GO:0006810=GO_REF:0000002, GO:0008270=GO_REF:0000019} O43823 A-kinase anchor protein 8 protein 20080818 {GO:0000793=IEA, GO:0007076=IEA, GO:0034237=IEA, GO:0005794=IEA, GO:0005730=IDA, GO:0005634=IDA, GO:0003677=IEA, GO:0016363=ISS, GO:0005739=IEA, GO:0007165=TAS, GO:0007067=TAS, GO:0001939=IEA, GO:0003690=IEA, GO:0016020=IEA, GO:0006810=IEA, GO:0008270=IEA} mitosis, mitotic chromosome condensation, signal transduction, transport Golgi apparatus, condensed chromosome, female pronucleus, membrane, mitochondrion, nuclear matrix, nucleolus, nucleus DNA binding, double-stranded DNA binding, protein kinase A regulatory subunit binding, zinc ion binding NOT Human AKAP8L IntAct UniProtKB {GO:0005515=PMID:18313049, GO:0008150=GO_REF:0000015, GO:0005737=GO_REF:0000039, GO:0017151=PMID:10748171, GO:0005634=PMID:10761695, GO:0003677=GO_REF:0000002, GO:0016363=PMID:16391387, GO:0046872=GO_REF:0000037} Q9ULX6 A-kinase anchor protein 8-like protein 20130415 {GO:0005515=IPI, GO:0008150=ND, GO:0005737=IEA, GO:0017151=TAS, GO:0005634=TAS, GO:0003677=IEA, GO:0016363=IDA, GO:0046872=IEA} biological_process cytoplasm, nuclear matrix, nucleus DEAD/H-box RNA helicase binding, DNA binding, metal ion binding, protein binding Human UniProtKB:Q68DV7 AKAP9 HPA UniProtKB {GO:0005515=PMID:12163479, GO:0005813=GO_REF:0000052, GO:0005794=GO_REF:0000052, GO:0005102=PMID:9482789, GO:0007268=PMID:9482789, GO:0043231=GO_REF:0000052, GO:0005829=Reactome:REACT_15470, GO:0007165=PMID:10390370, GO:0016301=GO_REF:0000038, GO:0000086=Reactome:REACT_2203, GO:0006810=PMID:10390370, GO:0005856=PMID:9482789, GO:0000278=Reactome:REACT_152, GO:0000242=GO_REF:0000019} Q99996 A-kinase anchor protein 9 protein 20120912 {GO:0005515=IPI, GO:0005813=IDA, GO:0005794=IDA, GO:0005102=TAS, GO:0007268=TAS, GO:0043231=IDA, GO:0005829=TAS, GO:0007165=TAS, GO:0016301=IEA, GO:0000086=TAS, GO:0006810=TAS, GO:0005856=TAS, GO:0000278=TAS, GO:0000242=IEA} G2/M transition of mitotic cell cycle, mitotic cell cycle, signal transduction, synaptic transmission, transport Golgi apparatus, centrosome, cytoskeleton, cytosol, intracellular membrane-bounded organelle, pericentriolar material kinase activity, protein binding, receptor binding Human AKD1 InterPro UniProtKB {GO:0017111=GO_REF:0000002, GO:0006139=GO_REF:0000002, GO:0005524=GO_REF:0000002, GO:0019205=GO_REF:0000002} Q5TCS8 Adenylate kinase domain-containing protein 1 protein 20130413 {GO:0017111=IEA, GO:0006139=IEA, GO:0005524=IEA, GO:0019205=IEA} nucleobase-containing compound metabolic process ATP binding, nucleobase-containing compound kinase activity, nucleoside-triphosphatase activity Human InterPro:IPR000850 AKIP1 IntAct UniProtKB {GO:0005515=PMID:15630084, GO:0034446=GO_REF:0000019, GO:0005634=GO_REF:0000039} Q9NQ31 A-kinase-interacting protein 1 protein 20130415 {GO:0005515=IPI, GO:0034446=IEA, GO:0005634=IEA} substrate adhesion-dependent cell spreading nucleus protein binding Human UniProtKB:P17612 AKIRIN1 HPA UniProtKB {GO:0031965=GO_REF:0000052, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0043231=GO_REF:0000052} Q9H9L7 Akirin-1 protein 20120912 {GO:0031965=IDA, GO:0005730=IDA, GO:0005634=IDA, GO:0043231=IDA} intracellular membrane-bounded organelle, nuclear membrane, nucleolus, nucleus Human AKIRIN2 UniProtKB UniProtKB {GO:0032755=GO_REF:0000019, GO:0008284=GO_REF:0000019, GO:0017053=GO_REF:0000024, GO:0045944=GO_REF:0000019, GO:0045087=GO_REF:0000037, GO:0010950=GO_REF:0000019, GO:0032496=GO_REF:0000019, GO:0005634=PMID:18066067, GO:0009790=GO_REF:0000019, GO:0000122=GO_REF:0000019, GO:0006351=GO_REF:0000037} Q53H80 Akirin-2 protein 20080923 {GO:0032755=IEA, GO:0008284=IEA, GO:0017053=ISS, GO:0045944=IEA, GO:0045087=IEA, GO:0010950=IEA, GO:0032496=IEA, GO:0005634=IDA, GO:0009790=IEA, GO:0000122=IEA, GO:0006351=IEA} embryo development, innate immune response, negative regulation of transcription from RNA polymerase II promoter, positive regulation of cell proliferation, positive regulation of endopeptidase activity, positive regulation of interleukin-6 production, positive regulation of transcription from RNA polymerase II promoter, response to lipopolysaccharide, transcription, DNA-dependent nucleus, transcriptional repressor complex Human AKNA UniProtKB UniProtKB {GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q7Z591 AT-hook-containing transcription factor protein 20130413 {GO:0006355=IEA, GO:0005634=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus DNA binding Human UniProtKB-SubCell:SL-0191 AKNAD1 HPA UniProtKB {GO:0005737=GO_REF:0000052} Q5T1N2 Protein AKNAD1 protein 20101115 {GO:0005737=IDA} cytoplasm Human AKR1A1 ENSEMBL UniProtKB {GO:0004032=PMID:2498333, GO:0016324=GO_REF:0000019, GO:0046185=GO_REF:0000019, GO:0019853=GO_REF:0000019, GO:0006081=PMID:2498333, GO:0042840=GO_REF:0000019, GO:0006006=PMID:2498333, GO:0009055=PMID:2498333, GO:0047939=GO_REF:0000019, GO:0005829=GO_REF:0000019} Q5T621 "Alcohol dehydrogenase ""NADP(+)""" protein 20130413 {GO:0004032=TAS, GO:0016324=IEA, GO:0046185=IEA, GO:0019853=IEA, GO:0006081=TAS, GO:0042840=IEA, GO:0006006=TAS, GO:0009055=TAS, GO:0047939=IEA, GO:0005829=IEA} D-glucuronate catabolic process, L-ascorbic acid biosynthetic process, aldehyde catabolic process, cellular aldehyde metabolic process, glucose metabolic process apical plasma membrane, cytosol L-glucuronate reductase activity, alditol:NADP+ 1-oxidoreductase activity, electron carrier activity Human Ensembl:ENSMUSP00000030455 AKR1B1 HPA UniProtKB {GO:0044598=PMID:20837989, GO:0044597=PMID:20837989, GO:0005975=PMID:2112546, GO:0043795=PMID:20837989, GO:0005730=GO_REF:0000052, GO:0006950=PMID:8435445, GO:0009055=PMID:2112546, GO:0005634=GO_REF:0000052, GO:0044281=Reactome:REACT_111217, GO:0005615=PMID:2112546, GO:0005829=Reactome:REACT_9986, GO:0004032=GO_REF:0000003, GO:0005737=GO_REF:0000052, GO:0004033=PMID:8435445, GO:0006700=Reactome:REACT_11038, GO:0016491=GO_REF:0000002, GO:0008202=Reactome:REACT_11057} P15121 Aldose reductase protein 20100326 {GO:0044598=IMP, GO:0044597=IMP, GO:0005975=TAS, GO:0043795=IDA, GO:0005730=IDA, GO:0006950=TAS, GO:0009055=TAS, GO:0005634=IDA, GO:0044281=TAS, GO:0005615=TAS, GO:0005829=TAS, GO:0004032=IEA, GO:0005737=IDA, GO:0004033=TAS, GO:0006700=TAS, GO:0016491=IEA, GO:0008202=TAS} C21-steroid hormone biosynthetic process, carbohydrate metabolic process, daunorubicin metabolic process, doxorubicin metabolic process, response to stress, small molecule metabolic process, steroid metabolic process cytoplasm, cytosol, extracellular space, nucleolus, nucleus alditol:NADP+ 1-oxidoreductase activity, aldo-keto reductase (NADP) activity, electron carrier activity, glyceraldehyde oxidoreductase activity, oxidoreductase activity Human AKR1B10 Reactome UniProtKB {GO:0044598=PMID:20837989, GO:0047718=PMID:20837989, GO:0045550=PMID:21187079, GO:0044597=PMID:20837989, GO:0007603=Reactome:REACT_160125, GO:0001758=PMID:21851338, GO:0007586=PMID:9565553, GO:0006081=PMID:9565553, GO:0005576=GO_REF:0000039, GO:0005575=GO_REF:0000015, GO:0001523=Reactome:REACT_24968, GO:0005764=GO_REF:0000039, GO:0005829=Reactome:REACT_160311, GO:0004033=PMID:9565553, GO:0016488=PMID:21187079, GO:0008202=PMID:9565553} O60218 Aldo-keto reductase family 1 member B10 protein 20130301 {GO:0044598=IMP, GO:0047718=IDA, GO:0045550=IDA, GO:0044597=IMP, GO:0007603=TAS, GO:0001758=IDA, GO:0007586=TAS, GO:0006081=TAS, GO:0005576=IEA, GO:0005575=ND, GO:0001523=TAS, GO:0005764=IEA, GO:0005829=TAS, GO:0004033=TAS, GO:0016488=IDA, GO:0008202=TAS} cellular aldehyde metabolic process, daunorubicin metabolic process, digestion, doxorubicin metabolic process, farnesol catabolic process, phototransduction, visible light, retinoid metabolic process, steroid metabolic process cellular_component, cytosol, extracellular region, lysosome aldo-keto reductase (NADP) activity, geranylgeranyl reductase activity, indanol dehydrogenase activity, retinal dehydrogenase activity Human AKR1C1 Reactome UniProtKB {GO:0044598=PMID:20837989, GO:0031406=PMID:8486699, GO:0046683=PMID:16079077, GO:0032052=PMID:8486699, GO:0006805=PMID:8486699, GO:0044597=PMID:20837989, GO:0007603=Reactome:REACT_160125, GO:0047086=PMID:21232532, GO:0005829=Reactome:REACT_160311, GO:0030299=PMID:8486699, GO:0016655=PMID:20837989, GO:0042574=PMID:21851338, GO:0071395=PMID:19487289, GO:0047115=PMID:8486699, GO:0008206=PMID:8486699, GO:0051260=PMID:8486699, GO:0047042=PMID:8486699, GO:0042632=PMID:8486699, GO:0047718=GO_REF:0000003, GO:0007586=PMID:8486699, GO:0047006=GO_REF:0000003, GO:0001523=Reactome:REACT_24968, GO:0004032=PMID:21232532, GO:0004033=PMID:7789999, GO:0015721=PMID:8486699, GO:0042448=PMID:21232532, GO:0016491=GO_REF:0000002, GO:0018636=PMID:21851338, GO:0055114=PMID:21232532} Q04828 Aldo-keto reductase family 1 member C1 protein 20130301 {GO:0044598=IMP, GO:0031406=IDA, GO:0046683=IEP, GO:0032052=IDA, GO:0006805=NAS, GO:0044597=IMP, GO:0007603=TAS, GO:0047086=IDA, GO:0005829=TAS, GO:0030299=TAS, GO:0016655=IDA, GO:0042574=IDA, GO:0071395=IDA, GO:0047115=IDA, GO:0008206=IDA, GO:0051260=IDA, GO:0047042=IDA, GO:0042632=TAS, GO:0047718=IEA, GO:0007586=IDA, GO:0047006=IEA, GO:0001523=TAS, GO:0004032=IDA, GO:0004033=TAS, GO:0015721=TAS, GO:0042448=IDA, GO:0016491=IEA, GO:0018636=IDA, GO:0055114=IDA} bile acid and bile salt transport, bile acid metabolic process, cellular response to jasmonic acid stimulus, cholesterol homeostasis, daunorubicin metabolic process, digestion, doxorubicin metabolic process, intestinal cholesterol absorption, oxidation-reduction process, phototransduction, visible light, progesterone metabolic process, protein homooligomerization, response to organophosphorus, retinal metabolic process, retinoid metabolic process, xenobiotic metabolic process cytosol 17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity, alditol:NADP+ 1-oxidoreductase activity, aldo-keto reductase (NADP) activity, androsterone dehydrogenase (B-specific) activity, bile acid binding, carboxylic acid binding, indanol dehydrogenase activity, ketosteroid monooxygenase activity, oxidoreductase activity, oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor, phenanthrene 9,10-monooxygenase activity, trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity Human AKR1C2 UniProtKB UniProtKB {GO:0044598=PMID:20837989, GO:0031406=PMID:8573067, GO:0032052=PMID:8573067, GO:0006693=PMID:8573067, GO:0044597=PMID:20837989, GO:0047086=PMID:21232532, GO:0007586=PMID:8573067, GO:0004032=PMID:21232532, GO:0005737=GO_REF:0000039, GO:0016655=PMID:20837989, GO:0007186=PMID:18508192, GO:0071395=PMID:19487289, GO:0047026=GO_REF:0000003, GO:0047115=PMID:8573067, GO:0042448=PMID:21232532, GO:0016491=GO_REF:0000002, GO:0018636=PMID:21851338, GO:0008202=PMID:8573067, GO:0055114=PMID:21232532} P52895 Aldo-keto reductase family 1 member C2 protein 20120508 {GO:0044598=IMP, GO:0031406=IDA, GO:0032052=IDA, GO:0006693=IDA, GO:0044597=IMP, GO:0047086=IDA, GO:0007586=IDA, GO:0004032=IDA, GO:0005737=IEA, GO:0016655=IDA, GO:0007186=IDA, GO:0071395=IDA, GO:0047026=IEA, GO:0047115=IDA, GO:0042448=IDA, GO:0016491=IEA, GO:0018636=IDA, GO:0008202=IDA, GO:0055114=IDA} G-protein coupled receptor signaling pathway, cellular response to jasmonic acid stimulus, daunorubicin metabolic process, digestion, doxorubicin metabolic process, oxidation-reduction process, progesterone metabolic process, prostaglandin metabolic process, steroid metabolic process cytoplasm alditol:NADP+ 1-oxidoreductase activity, androsterone dehydrogenase (A-specific) activity, bile acid binding, carboxylic acid binding, ketosteroid monooxygenase activity, oxidoreductase activity, oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor, phenanthrene 9,10-monooxygenase activity, trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity Human AKR1C3 LIFEdb UniProtKB {GO:0044598=PMID:20837989, GO:0019369=Reactome:REACT_147851, GO:0044597=PMID:20837989, GO:0006693=PMID:20036328, GO:0001758=PMID:21851338, GO:0007603=Reactome:REACT_160125, GO:0047017=GO_REF:0000003, GO:0005622=GO_REF:0000054, GO:0016488=PMID:21187079, GO:0047020=PMID:22170488, GO:0047026=GO_REF:0000003, GO:0071395=PMID:19487289, GO:0047023=PMID:16983398, GO:0047115=GO_REF:0000003, GO:0044259=PMID:18641923, GO:0004745=PMID:21851338, GO:0010942=PMID:21787718, GO:0045550=PMID:21187079, GO:1900053=PMID:21851338, GO:0061370=PMID:16983398, GO:0004032=PMID:21232532, GO:0004033=PMID:9792917, GO:0048385=PMID:21851338, GO:0007186=PMID:18508192, GO:0042448=PMID:21232532, GO:0016491=GO_REF:0000002, GO:2000379=PMID:19442656, GO:0055114=PMID:19442656, GO:0008284=PMID:21851338, GO:0047086=PMID:21232532, GO:0044281=Reactome:REACT_111217, GO:0070293=PMID:16157291, GO:0005829=Reactome:REACT_160311, GO:0016655=PMID:20837989, GO:0042574=PMID:21851338, GO:0071277=PMID:22170488, GO:0047787=PMID:16983398, GO:0047045=GO_REF:0000003, GO:0071276=PMID:21787718, GO:0071379=PMID:22170488, GO:0008202=PMID:20036328, GO:0019371=Reactome:REACT_150149, GO:0047718=GO_REF:0000003, GO:0001523=Reactome:REACT_24968, GO:0036131=GO_REF:0000003, GO:0035410=PMID:16983398, GO:0047035=GO_REF:0000003, GO:0034614=PMID:21787718, GO:0018636=PMID:21851338, GO:2000353=PMID:19442656, GO:0008584=PMID:19942269} P42330 Aldo-keto reductase family 1 member C3 protein 20100607 {GO:0044598=IMP, GO:0019369=TAS, GO:0044597=IMP, GO:0006693=IEP, GO:0001758=IDA, GO:0007603=TAS, GO:0047017=IEA, GO:0005622=IDA, GO:0016488=IDA, GO:0047020=IDA, GO:0047026=IEA, GO:0071395=IDA, GO:0047023=IDA, GO:0047115=IEA, GO:0044259=IEP, GO:0004745=IDA, GO:0010942=IDA, GO:0045550=IDA, GO:1900053=IDA, GO:0061370=IMP, GO:0004032=IDA, GO:0004033=TAS, GO:0048385=IDA, GO:0007186=IDA, GO:0042448=IDA, GO:0016491=IEA, GO:2000379=IDA, GO:0055114=IDA, GO:0008284=IMP, GO:0047086=IDA, GO:0044281=TAS, GO:0070293=NAS, GO:0005829=TAS, GO:0016655=IDA, GO:0042574=IDA, GO:0071277=IDA, GO:0047787=IDA, GO:0047045=IEA, GO:0071276=IDA, GO:0071379=IDA, GO:0008202=IEP, GO:0019371=TAS, GO:0047718=IEA, GO:0001523=TAS, GO:0036131=IEA, GO:0035410=IDA, GO:0047035=IEA, GO:0034614=IDA, GO:0018636=IDA, GO:2000353=IDA, GO:0008584=IEP} G-protein coupled receptor signaling pathway, arachidonic acid metabolic process, cellular response to cadmium ion, cellular response to calcium ion, cellular response to jasmonic acid stimulus, cellular response to prostaglandin stimulus, cellular response to reactive oxygen species, cyclooxygenase pathway, daunorubicin metabolic process, doxorubicin metabolic process, farnesol catabolic process, male gonad development, multicellular organismal macromolecule metabolic process, negative regulation of retinoic acid biosynthetic process, oxidation-reduction process, phototransduction, visible light, positive regulation of cell death, positive regulation of cell proliferation, positive regulation of endothelial cell apoptotic process, positive regulation of reactive oxygen species metabolic process, progesterone metabolic process, prostaglandin metabolic process, regulation of retinoic acid receptor signaling pathway, renal absorption, retinal metabolic process, retinoid metabolic process, small molecule metabolic process, steroid metabolic process, testosterone biosynthetic process cytosol, intracellular 15-hydroxyprostaglandin-D dehydrogenase (NADP+) activity, alditol:NADP+ 1-oxidoreductase activity, aldo-keto reductase (NADP) activity, androsterone dehydrogenase (A-specific) activity, androsterone dehydrogenase activity, delta4-3-oxosteroid 5beta-reductase activity, dihydrotestosterone 17-beta-dehydrogenase activity, geranylgeranyl reductase activity, indanol dehydrogenase activity, ketosteroid monooxygenase activity, oxidoreductase activity, oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor, phenanthrene 9,10-monooxygenase activity, prostaglandin D2 11-ketoreductase activity, prostaglandin-F synthase activity, retinal dehydrogenase activity, retinol dehydrogenase activity, testosterone 17-beta-dehydrogenase (NADP+) activity, testosterone dehydrogenase (NAD+) activity, trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity Human AKR1C4 Reactome UniProtKB {GO:0044598=PMID:20837989, GO:0044597=PMID:20837989, GO:0007603=Reactome:REACT_160125, GO:0001758=PMID:21851338, GO:0006699=Reactome:REACT_11054, GO:0008209=PMID:7650035, GO:0009055=PMID:8172617, GO:0044281=Reactome:REACT_111217, GO:0015125=PMID:8172617, GO:0001523=Reactome:REACT_24968, GO:0005829=Reactome:REACT_160311, GO:0047743=GO_REF:0000003, GO:0005737=PMID:2187532, GO:0004033=PMID:7650035, GO:0016655=PMID:20837989, GO:0071395=PMID:19487289, GO:0015721=PMID:8172617, GO:0047023=PMID:21851338, GO:0008206=Reactome:REACT_11040, GO:0047042=GO_REF:0000003, GO:0008202=PMID:8274401} P17516 Aldo-keto reductase family 1 member C4 protein 20130301 {GO:0044598=IMP, GO:0044597=IMP, GO:0007603=TAS, GO:0001758=IDA, GO:0006699=TAS, GO:0008209=TAS, GO:0009055=TAS, GO:0044281=TAS, GO:0015125=TAS, GO:0001523=TAS, GO:0005829=TAS, GO:0047743=IEA, GO:0005737=TAS, GO:0004033=TAS, GO:0016655=IDA, GO:0071395=IDA, GO:0015721=TAS, GO:0047023=IDA, GO:0008206=TAS, GO:0047042=IEA, GO:0008202=TAS} androgen metabolic process, bile acid and bile salt transport, bile acid biosynthetic process, bile acid metabolic process, cellular response to jasmonic acid stimulus, daunorubicin metabolic process, doxorubicin metabolic process, phototransduction, visible light, retinoid metabolic process, small molecule metabolic process, steroid metabolic process cytoplasm, cytosol aldo-keto reductase (NADP) activity, androsterone dehydrogenase (B-specific) activity, androsterone dehydrogenase activity, bile acid transmembrane transporter activity, chlordecone reductase activity, electron carrier activity, oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor, retinal dehydrogenase activity Human AKR1D1 Reactome UniProtKB {GO:0006707=PMID:7508385, GO:0006699=Reactome:REACT_11054, GO:0008209=PMID:7508385, GO:0030573=GO_REF:0000037, GO:0007586=PMID:7508385, GO:0047787=GO_REF:0000003, GO:0008206=Reactome:REACT_11040, GO:0044281=Reactome:REACT_111217, GO:0008207=PMID:7508385, GO:0005496=PMID:7508385, GO:0005829=Reactome:REACT_10131, GO:0055114=PMID:7508385} P51857 3-oxo-5-beta-steroid 4-dehydrogenase protein 20130301 {GO:0006707=IDA, GO:0006699=TAS, GO:0008209=IDA, GO:0030573=IEA, GO:0007586=IDA, GO:0047787=IEA, GO:0008206=TAS, GO:0044281=TAS, GO:0008207=IDA, GO:0005496=TAS, GO:0005829=TAS, GO:0055114=IDA} C21-steroid hormone metabolic process, androgen metabolic process, bile acid biosynthetic process, bile acid catabolic process, bile acid metabolic process, cholesterol catabolic process, digestion, oxidation-reduction process, small molecule metabolic process cytosol delta4-3-oxosteroid 5beta-reductase activity, steroid binding Human AKR7A2 PINC UniProtKB {GO:0044598=PMID:20837989, GO:0019119=PMID:20837989, GO:0005739=GO_REF:0000019, GO:0004032=GO_REF:0000019, GO:0044597=PMID:20837989, GO:0005794=GO_REF:0000039, GO:0005975=PMID:9576847, GO:0006081=PMID:9576847, GO:0009055=PMID:9576847} O43488 Aflatoxin B1 aldehyde reductase member 2 protein 20030904 {GO:0044598=IMP, GO:0019119=IDA, GO:0005739=IEA, GO:0004032=IEA, GO:0044597=IMP, GO:0005794=IEA, GO:0005975=TAS, GO:0006081=TAS, GO:0009055=TAS} carbohydrate metabolic process, cellular aldehyde metabolic process, daunorubicin metabolic process, doxorubicin metabolic process Golgi apparatus, mitochondrion alditol:NADP+ 1-oxidoreductase activity, electron carrier activity, phenanthrene-9,10-epoxide hydrolase activity Human AKR7A3 PINC UniProtKB {GO:0004032=GO_REF:0000019, GO:0004033=PMID:10383892, GO:0006081=PMID:10383892, GO:0009055=PMID:10383892, GO:0046223=GO_REF:0000019, GO:0005829=PMID:10383892} O95154 Aflatoxin B1 aldehyde reductase member 3 protein 20030904 {GO:0004032=IEA, GO:0004033=TAS, GO:0006081=TAS, GO:0009055=TAS, GO:0046223=IEA, GO:0005829=TAS} aflatoxin catabolic process, cellular aldehyde metabolic process cytosol alditol:NADP+ 1-oxidoreductase activity, aldo-keto reductase (NADP) activity, electron carrier activity Human AKR7L UniProtKB UniProtKB {GO:0016491=GO_REF:0000037} Q8NHP1 Aflatoxin B1 aldehyde reductase member 4 protein 20130413 {GO:0016491=IEA} oxidoreductase activity Human UniProtKB-KW:KW-0560 AKT1 BHF-UCL UniProtKB {GO:0005515=PMID:19162005, GO:0042640=GO_REF:0000019, GO:0030307=PMID:19203586, GO:0007281=GO_REF:0000019, GO:0030154=PMID:21432781, GO:0046889=PMID:8940145, GO:0030163=GO_REF:0000019, GO:0046329=GO_REF:0000019, GO:0046777=PMID:16280327, GO:1901976=PMID:21432781, GO:1900740=Reactome:REACT_697, GO:0008637=GO_REF:0000019, GO:0060644=PMID:21432781, GO:0015758=GO_REF:0000019, GO:0018105=PMID:16139227, GO:0046326=PMID:8940145, GO:0005080=GO_REF:0000019, GO:0060716=GO_REF:0000019, GO:0000060=PMID:16280327, GO:0005979=PMID:8940145, GO:0032869=GO_REF:0000024, GO:0005978=GO_REF:0000019, GO:0005819=GO_REF:0000019, GO:0001893=GO_REF:0000019, GO:0010748=PMID:16814735, GO:0030168=Reactome:REACT_798, GO:0070141=PMID:18483258, GO:0032270=GO_REF:0000024, GO:0051000=PMID:10376603, GO:0045087=Reactome:REACT_6802, GO:0051146=GO_REF:0000019, GO:0016044=Reactome:REACT_11123, GO:0016567=GO_REF:0000019, GO:0050999=Reactome:REACT_12477, GO:0005634=GO_REF:0000052, GO:0044281=Reactome:REACT_111217, GO:0032094=GO_REF:0000019, GO:0005829=Reactome:REACT_160114, GO:0032880=GO_REF:0000019, GO:0051091=PMID:19057511, GO:0033138=PMID:19667065, GO:0006954=GO_REF:0000019, GO:0045907=GO_REF:0000019, GO:0006006=GO_REF:0000019, GO:0046209=Reactome:REACT_12508, GO:0030235=PMID:10376603, GO:0043154=GO_REF:0000024, GO:0048011=Reactome:REACT_11061, GO:0045725=PMID:17925406, GO:0043325=PMID:19203586, GO:0048015=Reactome:REACT_12464, GO:0071456=GO_REF:0000019, GO:0042593=GO_REF:0000019, GO:0032287=GO_REF:0000019, GO:0006417=GO_REF:0000037, GO:0045861=PMID:18387192, GO:0004672=PMID:10570282, GO:0071364=GO_REF:0000019, GO:0004674=PMID:19667065, GO:0007596=Reactome:REACT_604, GO:0048009=PMID:8978681, GO:0010467=Reactome:REACT_71, GO:0009408=PMID:10958679, GO:0034405=PMID:10376603, GO:0006412=GO_REF:0000019, GO:0010907=PMID:16814735, GO:0006809=PMID:10376602, GO:0042802=PMID:16280327, GO:0007173=Reactome:REACT_9417, GO:0010765=GO_REF:0000019, GO:0016301=PMID:14749367, GO:0030334=PMID:21432781, GO:0016070=Reactome:REACT_21257, GO:0016071=Reactome:REACT_20605, GO:0007568=GO_REF:0000019, GO:0005547=PMID:19203586, GO:0030027=GO_REF:0000019, GO:0001649=GO_REF:0000019, GO:0043536=PMID:20011604, GO:0016310=PMID:20333297, GO:0045792=GO_REF:0000019, GO:0007186=PMID:10570282, GO:0008543=Reactome:REACT_9470, GO:0010975=GO_REF:0000024, GO:0030030=GO_REF:0000019, GO:0010507=PMID:18387192, GO:0045600=PMID:8940145, GO:0043491=GO_REF:0000019, GO:0005654=Reactome:REACT_147870, GO:0019899=GO_REF:0000024, GO:0008286=PMID:8978681, GO:0005886=Reactome:REACT_147896, GO:0031999=PMID:16814735, GO:0008283=PMID:21432781, GO:0031295=Reactome:REACT_19344, GO:0032436=GO_REF:0000019, GO:0006924=PMID:14749367, GO:0045429=PMID:10376603, GO:0035556=PMID:14749367, GO:0005737=GO_REF:0000024, GO:0005543=GO_REF:0000002, GO:0090201=GO_REF:0000024, GO:0045944=GO_REF:0000019, GO:0015630=GO_REF:0000052, GO:0060709=GO_REF:0000019, GO:0043066=PMID:16604263, GO:0043065=GO_REF:0000019, GO:0006915=Reactome:REACT_578, GO:0005524=PMID:16540465, GO:0097193=Reactome:REACT_964, GO:0010951=PMID:18387192, GO:0007165=PMID:21432781, GO:0031659=PMID:18483258, GO:0031018=Reactome:REACT_13819, GO:0001934=PMID:19057511, GO:0006468=PMID:14749367, GO:0006469=GO_REF:0000024, GO:0006464=PMID:10570282, GO:0090004=PMID:8940145} P31749 RAC-alpha serine/threonine-protein kinase protein 20110127 {GO:0005515=IPI, GO:0042640=IEA, GO:0030307=IDA, GO:0007281=IEA, GO:0030154=TAS, GO:0046889=IMP, GO:0030163=IEA, GO:0046329=IEA, GO:0046777=TAS, GO:1901976=TAS, GO:1900740=TAS, GO:0008637=IEA, GO:0060644=TAS, GO:0015758=IEA, GO:0018105=IDA, GO:0046326=IMP, GO:0005080=IEA, GO:0060716=IEA, GO:0000060=IMP, GO:0005979=IMP, GO:0032869=ISS, GO:0005978=IEA, GO:0005819=IEA, GO:0001893=IEA, GO:0010748=IMP, GO:0030168=TAS, GO:0070141=IDA, GO:0032270=ISS, GO:0051000=IMP, GO:0045087=TAS, GO:0051146=IEA, GO:0016044=TAS, GO:0016567=IEA, GO:0050999=TAS, GO:0005634=IDA, GO:0044281=TAS, GO:0032094=IEA, GO:0005829=TAS, GO:0032880=IEA, GO:0051091=IDA, GO:0033138=IDA, GO:0006954=IEA, GO:0045907=IEA, GO:0006006=IEA, GO:0046209=TAS, GO:0030235=IMP, GO:0043154=ISS, GO:0048011=TAS, GO:0045725=NAS, GO:0043325=IDA, GO:0048015=TAS, GO:0071456=IEA, GO:0042593=IEA, GO:0032287=IEA, GO:0006417=IEA, GO:0045861=IMP, GO:0004672=TAS, GO:0071364=IEA, GO:0004674=IDA, GO:0007596=TAS, GO:0048009=IMP, GO:0010467=TAS, GO:0009408=TAS, GO:0034405=IMP, GO:0006412=IEA, GO:0010907=IMP, GO:0006809=TAS, GO:0042802=IPI, GO:0007173=TAS, GO:0010765=IEA, GO:0016301=IDA, GO:0030334=TAS, GO:0016070=TAS, GO:0016071=TAS, GO:0007568=IEA, GO:0005547=IDA, GO:0030027=IEA, GO:0001649=IEA, GO:0043536=IDA, GO:0016310=IDA, GO:0045792=IEA, GO:0007186=TAS, GO:0008543=TAS, GO:0010975=ISS, GO:0030030=IEA, GO:0010507=IMP, GO:0045600=IMP, GO:0043491=IEA, GO:0005654=TAS, GO:0019899=ISS, GO:0008286=IMP, GO:0005886=TAS, GO:0031999=IMP, GO:0008283=TAS, GO:0031295=TAS, GO:0032436=IEA, GO:0006924=IMP, GO:0045429=IMP, GO:0035556=IDA, GO:0005737=ISS, GO:0005543=IEA, GO:0090201=ISS, GO:0045944=IEA, GO:0015630=IDA, GO:0060709=IEA, GO:0043066=NAS, GO:0043065=IEA, GO:0006915=TAS, GO:0005524=IDA, GO:0097193=TAS, GO:0010951=IMP, GO:0007165=TAS, GO:0031659=IDA, GO:0031018=TAS, GO:0001934=IDA, GO:0006468=IDA, GO:0006469=ISS, GO:0006464=TAS, GO:0090004=IMP} G-protein coupled receptor signaling pathway, RNA metabolic process, T cell costimulation, activation-induced cell death of T cells, aging, anagen, apoptotic mitochondrial changes, apoptotic process, blood coagulation, cell differentiation, cell projection organization, cell proliferation, cellular membrane organization, cellular protein modification process, cellular response to epidermal growth factor stimulus, cellular response to hypoxia, cellular response to insulin stimulus, endocrine pancreas development, epidermal growth factor receptor signaling pathway, fibroblast growth factor receptor signaling pathway, gene expression, germ cell development, glucose homeostasis, glucose metabolic process, glucose transport, glycogen biosynthetic process, glycogen cell differentiation involved in embryonic placenta development, inflammatory response, innate immune response, insulin receptor signaling pathway, insulin-like growth factor receptor signaling pathway, intracellular signal transduction, intrinsic apoptotic signaling pathway, labyrinthine layer blood vessel development, mRNA metabolic process, mammary gland epithelial cell differentiation, maternal placenta development, negative regulation of JNK cascade, negative regulation of apoptotic process, negative regulation of autophagy, negative regulation of cell size, negative regulation of cysteine-type endopeptidase activity involved in apoptotic process, negative regulation of endopeptidase activity, negative regulation of fatty acid beta-oxidation, negative regulation of plasma membrane long-chain fatty acid transport, negative regulation of protein kinase activity, negative regulation of proteolysis, negative regulation of release of cytochrome c from mitochondria, neurotrophin TRK receptor signaling pathway, nitric oxide biosynthetic process, nitric oxide metabolic process, osteoblast differentiation, peptidyl-serine phosphorylation, peripheral nervous system myelin maintenance, phosphatidylinositol-mediated signaling, phosphorylation, platelet activation, positive regulation of apoptotic process, positive regulation of blood vessel endothelial cell migration, positive regulation of cell growth, positive regulation of cellular protein metabolic process, positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S, positive regulation of establishment of protein localization to plasma membrane, positive regulation of fat cell differentiation, positive regulation of glucose import, positive regulation of glucose metabolic process, positive regulation of glycogen biosynthetic process, positive regulation of lipid biosynthetic process, positive regulation of nitric oxide biosynthetic process, positive regulation of nitric-oxide synthase activity, positive regulation of peptidyl-serine phosphorylation, positive regulation of proteasomal ubiquitin-dependent protein catabolic process, positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway, positive regulation of protein phosphorylation, positive regulation of sequence-specific DNA binding transcription factor activity, positive regulation of sodium ion transport, positive regulation of transcription from RNA polymerase II promoter, positive regulation of vasoconstriction, protein autophosphorylation, protein catabolic process, protein import into nucleus, translocation, protein kinase B signaling cascade, protein phosphorylation, protein ubiquitination, regulation of cell cycle checkpoint, regulation of cell migration, regulation of glycogen biosynthetic process, regulation of neuron projection development, regulation of nitric-oxide synthase activity, regulation of protein localization, regulation of translation, response to UV-A, response to fluid shear stress, response to food, response to heat, signal transduction, small molecule metabolic process, striated muscle cell differentiation, translation cytoplasm, cytosol, lamellipodium, microtubule cytoskeleton, nucleoplasm, nucleus, plasma membrane, spindle ATP binding, enzyme binding, identical protein binding, kinase activity, nitric-oxide synthase regulator activity, phosphatidylinositol-3,4,5-trisphosphate binding, phosphatidylinositol-3,4-bisphosphate binding, phospholipid binding, protein binding, protein kinase C binding, protein kinase activity, protein serine/threonine kinase activity Human AKT1S1 Reactome UniProtKB {GO:0005515=PMID:17386266, GO:0032007=PMID:17386266, GO:0048011=Reactome:REACT_11061, GO:0048015=Reactome:REACT_12464, GO:0005634=GO_REF:0000019, GO:0005829=Reactome:REACT_147737, GO:0044445=GO_REF:0000024, GO:0043234=GO_REF:0000019, GO:0043523=GO_REF:0000024, GO:0045792=PMID:17386266, GO:0031931=PMID:17386266, GO:0007173=Reactome:REACT_9417, GO:0008543=Reactome:REACT_9470, GO:0045087=Reactome:REACT_6802, GO:0006469=PMID:17386266} Q96B36 Proline-rich AKT1 substrate 1 protein 20130301 {GO:0005515=IPI, GO:0032007=IDA, GO:0048011=TAS, GO:0048015=TAS, GO:0005634=IEA, GO:0005829=TAS, GO:0044445=ISS, GO:0043234=IEA, GO:0043523=ISS, GO:0045792=IDA, GO:0031931=IDA, GO:0007173=TAS, GO:0008543=TAS, GO:0045087=TAS, GO:0006469=IDA} epidermal growth factor receptor signaling pathway, fibroblast growth factor receptor signaling pathway, innate immune response, negative regulation of TOR signaling cascade, negative regulation of cell size, negative regulation of protein kinase activity, neurotrophin TRK receptor signaling pathway, phosphatidylinositol-mediated signaling, regulation of neuron apoptotic process TORC1 complex, cytosol, cytosolic part, nucleus, protein complex protein binding Human AKT2 UniProtKB UniProtKB {GO:0008286=PMID:16814735, GO:0005515=PMID:22939624, GO:0071156=PMID:21432781, GO:0032859=GO_REF:0000019, GO:0005886=GO_REF:0000024, GO:0031340=GO_REF:0000024, GO:0008643=GO_REF:0000037, GO:0005634=PMID:21432781, GO:2000147=PMID:17332325, GO:0010907=PMID:16814735, GO:0005829=Reactome:REACT_6952, GO:0046328=GO_REF:0000019, GO:0005543=GO_REF:0000002, GO:0060644=PMID:21432781, GO:0016301=Reactome:REACT_6952, GO:0046326=PMID:16814735, GO:0006006=GO_REF:0000037, GO:0045444=PMID:21432781, GO:0005938=GO_REF:0000024, GO:0030334=PMID:21432781, GO:0032869=PMID:16814735, GO:0045725=PMID:16814735, GO:0005978=GO_REF:0000037, GO:0090314=GO_REF:0000024, GO:0006915=GO_REF:0000037, GO:0010748=PMID:16814735, GO:0032587=GO_REF:0000024, GO:0005524=GO_REF:0000038, GO:0072659=GO_REF:0000019, GO:0006417=GO_REF:0000037, GO:0032287=GO_REF:0000019, GO:0030027=GO_REF:0000019, GO:0065002=GO_REF:0000024, GO:2001275=GO_REF:0000019, GO:0007165=PMID:21432781, GO:0004672=GO_REF:0000002, GO:0004674=GO_REF:0000038, GO:0032000=PMID:16814735, GO:0001934=GO_REF:0000024, GO:0016044=Reactome:REACT_11123, GO:0006464=PMID:1409633} Q0VAN0 RAC-beta serine/threonine-protein kinase protein 20130413 {GO:0008286=IMP, GO:0005515=IPI, GO:0071156=TAS, GO:0032859=IEA, GO:0005886=ISS, GO:0031340=ISS, GO:0008643=IEA, GO:0005634=TAS, GO:2000147=IMP, GO:0010907=IMP, GO:0005829=TAS, GO:0046328=IEA, GO:0005543=IEA, GO:0060644=TAS, GO:0016301=TAS, GO:0046326=IMP, GO:0006006=IEA, GO:0045444=TAS, GO:0005938=ISS, GO:0030334=TAS, GO:0032869=IMP, GO:0045725=IMP, GO:0005978=IEA, GO:0090314=ISS, GO:0006915=IEA, GO:0010748=IMP, GO:0032587=ISS, GO:0005524=IEA, GO:0072659=IEA, GO:0006417=IEA, GO:0032287=IEA, GO:0030027=IEA, GO:0065002=ISS, GO:2001275=IEA, GO:0007165=TAS, GO:0004672=IEA, GO:0004674=IEA, GO:0032000=IMP, GO:0001934=ISS, GO:0016044=TAS, GO:0006464=TAS} activation of Ral GTPase activity, apoptotic process, carbohydrate transport, cellular membrane organization, cellular protein modification process, cellular response to insulin stimulus, fat cell differentiation, glucose metabolic process, glycogen biosynthetic process, insulin receptor signaling pathway, intracellular protein transmembrane transport, mammary gland epithelial cell differentiation, negative regulation of plasma membrane long-chain fatty acid transport, peripheral nervous system myelin maintenance, positive regulation of cell motility, positive regulation of fatty acid beta-oxidation, positive regulation of glucose import, positive regulation of glucose import in response to insulin stimulus, positive regulation of glucose metabolic process, positive regulation of glycogen biosynthetic process, positive regulation of protein phosphorylation, positive regulation of protein targeting to membrane, positive regulation of vesicle fusion, protein localization to plasma membrane, regulation of JNK cascade, regulation of cell cycle arrest, regulation of cell migration, regulation of translation, signal transduction cell cortex, cytosol, lamellipodium, nucleus, plasma membrane, ruffle membrane ATP binding, kinase activity, phospholipid binding, protein binding, protein kinase activity, protein serine/threonine kinase activity Human UniProtKB-KW:KW-0067 AKT3 HPA UniProtKB {GO:0005515=PMID:19713527, GO:0005794=GO_REF:0000052, GO:0005886=GO_REF:0000052, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0005524=PMID:16540465, GO:0007165=PMID:18524868, GO:0005737=GO_REF:0000052, GO:0005543=GO_REF:0000002, GO:0004672=PMID:10092583, GO:0004674=PMID:16540465, GO:0006468=PMID:10092583, GO:0000002=PMID:18524868} Q9Y243 RAC-gamma serine/threonine-protein kinase protein 20101115 {GO:0005515=IPI, GO:0005794=IDA, GO:0005886=IDA, GO:0005730=IDA, GO:0005634=IDA, GO:0005524=IDA, GO:0007165=IMP, GO:0005737=IDA, GO:0005543=IEA, GO:0004672=TAS, GO:0004674=IDA, GO:0006468=TAS, GO:0000002=IMP} mitochondrial genome maintenance, protein phosphorylation, signal transduction Golgi apparatus, cytoplasm, nucleolus, nucleus, plasma membrane ATP binding, phospholipid binding, protein binding, protein kinase activity, protein serine/threonine kinase activity Human AKTIP HPA UniProtKB {GO:0005515=PMID:18799622, GO:0030897=PMID:18799622, GO:0005794=GO_REF:0000052, GO:0016881=GO_REF:0000002, GO:0005886=GO_REF:0000052, GO:0008333=PMID:18799622, GO:0005730=GO_REF:0000052, GO:0006915=GO_REF:0000037, GO:0015031=GO_REF:0000037, GO:0045022=PMID:18799622, GO:0032092=PMID:14749367, GO:0005737=GO_REF:0000052, GO:0019787=PMID:18799622, GO:0001934=PMID:14749367, GO:0007032=PMID:18799622, GO:0007040=PMID:18799622, GO:0070695=PMID:18799622} Q9H8T0 AKT-interacting protein protein 20120912 {GO:0005515=IPI, GO:0030897=IDA, GO:0005794=IDA, GO:0016881=IEA, GO:0005886=IDA, GO:0008333=IMP, GO:0005730=IDA, GO:0006915=IEA, GO:0015031=IEA, GO:0045022=IMP, GO:0032092=IDA, GO:0005737=IDA, GO:0019787=NAS, GO:0001934=IDA, GO:0007032=IMP, GO:0007040=IMP, GO:0070695=IDA} apoptotic process, early endosome to late endosome transport, endosome organization, endosome to lysosome transport, lysosome organization, positive regulation of protein binding, positive regulation of protein phosphorylation, protein transport FHF complex, Golgi apparatus, HOPS complex, cytoplasm, nucleolus, plasma membrane acid-amino acid ligase activity, protein binding, small conjugating protein ligase activity Human ALAD Reactome UniProtKB {GO:0032791=PMID:11032836, GO:0044281=Reactome:REACT_111217, GO:0004655=Reactome:REACT_9430, GO:0033014=GO_REF:0000002, GO:0006782=GO_REF:0000041, GO:0003824=PMID:2063868, GO:0046872=GO_REF:0000002, GO:0042802=PMID:11032836, GO:0006783=Reactome:REACT_9465, GO:0005829=Reactome:REACT_9437, GO:0006778=Reactome:REACT_9431, GO:0006779=GO_REF:0000038, GO:0008270=PMID:11032836, GO:0051260=PMID:11032836} P13716 Delta-aminolevulinic acid dehydratase protein 20080604 {GO:0032791=IDA, GO:0044281=TAS, GO:0004655=TAS, GO:0033014=IEA, GO:0006782=IEA, GO:0003824=TAS, GO:0046872=IEA, GO:0042802=IPI, GO:0006783=TAS, GO:0005829=TAS, GO:0006778=TAS, GO:0006779=IEA, GO:0008270=IDA, GO:0051260=IPI} heme biosynthetic process, porphyrin-containing compound biosynthetic process, porphyrin-containing compound metabolic process, protein homooligomerization, protoporphyrinogen IX biosynthetic process, small molecule metabolic process, tetrapyrrole biosynthetic process cytosol catalytic activity, identical protein binding, lead ion binding, metal ion binding, porphobilinogen synthase activity, zinc ion binding Human ALAS1 HPA UniProtKB {GO:0009058=GO_REF:0000002, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0044281=Reactome:REACT_111217, GO:0003824=GO_REF:0000002, GO:0006782=GO_REF:0000041, GO:0006783=Reactome:REACT_9465, GO:0005739=GO_REF:0000052, GO:0005737=GO_REF:0000052, GO:0006778=Reactome:REACT_9431, GO:0005759=Reactome:REACT_115949, GO:0030170=GO_REF:0000002, GO:0003870=GO_REF:0000003, GO:0044255=Reactome:REACT_22279} P13196 5-aminolevulinate synthase, nonspecific, mitochondrial protein 20110516 {GO:0009058=IEA, GO:0005730=IDA, GO:0005634=IDA, GO:0044281=TAS, GO:0003824=IEA, GO:0006782=IEA, GO:0006783=TAS, GO:0005739=IDA, GO:0005737=IDA, GO:0006778=TAS, GO:0005759=TAS, GO:0030170=IEA, GO:0003870=IEA, GO:0044255=TAS} biosynthetic process, cellular lipid metabolic process, heme biosynthetic process, porphyrin-containing compound metabolic process, protoporphyrinogen IX biosynthetic process, small molecule metabolic process cytoplasm, mitochondrial matrix, mitochondrion, nucleolus, nucleus 5-aminolevulinate synthase activity, catalytic activity, pyridoxal phosphate binding Human ALAS2 InterPro UniProtKB {GO:0042541=GO_REF:0000024, GO:0005515=PMID:14643893, GO:0050662=GO_REF:0000024, GO:0001666=PMID:16234850, GO:0009058=GO_REF:0000002, GO:0005743=PMID:14643893, GO:0044281=Reactome:REACT_111217, GO:0033014=GO_REF:0000002, GO:0006782=GO_REF:0000041, GO:0006783=Reactome:REACT_9465, GO:0006879=GO_REF:0000024, GO:0005739=PMID:10727444, GO:0006778=GO_REF:0000002, GO:0005759=GO_REF:0000002, GO:0030170=GO_REF:0000002, GO:0030218=PMID:2050125, GO:0016594=GO_REF:0000024, GO:0003870=GO_REF:0000002, GO:0032364=PMID:16234850} Q5JZF5 Aminolevulinate, delta-, synthase 2 (Sideroblastic/hypochromic anemia), isoform CRA_a protein 20130413 {GO:0042541=ISS, GO:0005515=IPI, GO:0050662=ISS, GO:0001666=IDA, GO:0009058=IEA, GO:0005743=IDA, GO:0044281=TAS, GO:0033014=IEA, GO:0006782=IEA, GO:0006783=TAS, GO:0006879=ISS, GO:0005739=IDA, GO:0006778=IEA, GO:0005759=IEA, GO:0030170=IEA, GO:0030218=NAS, GO:0016594=ISS, GO:0003870=IEA, GO:0032364=NAS} biosynthetic process, cellular iron ion homeostasis, erythrocyte differentiation, heme biosynthetic process, hemoglobin biosynthetic process, oxygen homeostasis, porphyrin-containing compound metabolic process, protoporphyrinogen IX biosynthetic process, response to hypoxia, small molecule metabolic process, tetrapyrrole biosynthetic process mitochondrial inner membrane, mitochondrial matrix, mitochondrion 5-aminolevulinate synthase activity, coenzyme binding, glycine binding, protein binding, pyridoxal phosphate binding Human InterPro:IPR010961 ALB BHF-UCL UniProtKB {GO:0006629=Reactome:REACT_602, GO:0005515=PMID:16099937, GO:0043498=GO_REF:0000019, GO:0051087=PMID:19996109, GO:0043252=Reactome:REACT_23988, GO:0044281=Reactome:REACT_111217, GO:0005615=PMID:19996109, GO:0043069=PMID:14726550, GO:0019836=PMID:16394536, GO:0008144=PMID:10940303, GO:0006810=PMID:12617161, GO:0031093=Reactome:REACT_21351, GO:0008206=Reactome:REACT_11040, GO:0046010=GO_REF:0000019, GO:0009267=PMID:16245148, GO:0005504=PMID:9731778, GO:0043066=PMID:16153637, GO:0010033=GO_REF:0000019, GO:0016209=PMID:14726550, GO:0005507=PMID:14726550, GO:0007584=GO_REF:0000019, GO:0030168=Reactome:REACT_798, GO:0005576=Reactome:REACT_160182, GO:0055085=Reactome:REACT_19118, GO:0003677=PMID:16405401, GO:0005604=GO_REF:0000019, GO:0043234=PMID:16283771, GO:0019825=PMID:16283771, GO:0007596=Reactome:REACT_604, GO:0015721=Reactome:REACT_11042, GO:0030170=PMID:16201370, GO:0015643=PMID:16169013, GO:0002576=Reactome:REACT_318, GO:0042157=Reactome:REACT_13621, GO:0008270=GO_REF:0000019, GO:0051659=PMID:16153637, GO:0070541=GO_REF:0000019, GO:0019899=GO_REF:0000019, GO:0046689=GO_REF:0000019} P02768 Serum albumin protein 20100113 {GO:0006629=TAS, GO:0005515=IPI, GO:0043498=IEA, GO:0051087=IPI, GO:0043252=TAS, GO:0044281=TAS, GO:0005615=IDA, GO:0043069=NAS, GO:0019836=IDA, GO:0008144=NAS, GO:0006810=TAS, GO:0031093=TAS, GO:0008206=TAS, GO:0046010=IEA, GO:0009267=IDA, GO:0005504=NAS, GO:0043066=IDA, GO:0010033=IEA, GO:0016209=NAS, GO:0005507=NAS, GO:0007584=IEA, GO:0030168=TAS, GO:0005576=TAS, GO:0055085=TAS, GO:0003677=IDA, GO:0005604=IEA, GO:0043234=IDA, GO:0019825=IDA, GO:0007596=TAS, GO:0015721=TAS, GO:0030170=IDA, GO:0015643=IDA, GO:0002576=TAS, GO:0042157=TAS, GO:0008270=IEA, GO:0051659=IDA, GO:0070541=IEA, GO:0019899=IEA, GO:0046689=IEA} bile acid and bile salt transport, bile acid metabolic process, blood coagulation, cellular response to starvation, hemolysis by symbiont of host erythrocytes, lipid metabolic process, lipoprotein metabolic process, maintenance of mitochondrion location, negative regulation of apoptotic process, negative regulation of programmed cell death, platelet activation, platelet degranulation, positive regulation of circadian sleep/wake cycle, non-REM sleep, response to mercury ion, response to nutrient, response to organic substance, response to platinum ion, small molecule metabolic process, sodium-independent organic anion transport, transmembrane transport, transport basement membrane, extracellular region, extracellular space, platelet alpha granule lumen, protein complex DNA binding, antioxidant activity, cell surface binding, chaperone binding, copper ion binding, drug binding, enzyme binding, fatty acid binding, oxygen binding, protein binding, pyridoxal phosphate binding, toxic substance binding, zinc ion binding Human ALCAM UniProtKB UniProtKB {GO:0007165=PMID:7760007, GO:0030424=GO_REF:0000019, GO:0008045=GO_REF:0000019, GO:0016020=GO_REF:0000038, GO:0007411=Reactome:REACT_18266, GO:0005102=PMID:7760007, GO:0043025=GO_REF:0000019, GO:0016021=GO_REF:0000037, GO:0007155=GO_REF:0000037, GO:0009897=GO_REF:0000019} Q6ZS95 cDNA FLJ45715 fis, clone FELNG2000720, highly similar to CD166 antigen protein 20130413 {GO:0007165=TAS, GO:0030424=IEA, GO:0008045=IEA, GO:0016020=IEA, GO:0007411=TAS, GO:0005102=TAS, GO:0043025=IEA, GO:0016021=IEA, GO:0007155=IEA, GO:0009897=IEA} axon guidance, cell adhesion, motor neuron axon guidance, signal transduction axon, external side of plasma membrane, integral to membrane, membrane, neuronal cell body receptor binding Human UniProtKB-KW:KW-0472 ALDH16A1 InterPro UniProtKB {GO:0016620=GO_REF:0000002} Q8IZ83 Aldehyde dehydrogenase family 16 member A1 protein 20130413 {GO:0016620=IEA} oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor Human InterPro:IPR016163 ALDH18A1 HPA UniProtKB {GO:0019240=PMID:11092761, GO:0006536=PMID:11092761, GO:0055129=GO_REF:0000041, GO:0005743=Reactome:REACT_21319, GO:0004349=PMID:11092761, GO:0008652=Reactome:REACT_238, GO:0044281=Reactome:REACT_111217, GO:0005524=GO_REF:0000037, GO:0005739=GO_REF:0000052, GO:0034641=Reactome:REACT_13, GO:0004350=PMID:11092761, GO:0005737=GO_REF:0000052, GO:0006592=PMID:11092761, GO:0006561=PMID:11092761} P54886 Delta-1-pyrroline-5-carboxylate synthase protein 20090616 {GO:0019240=IMP, GO:0006536=IMP, GO:0055129=IEA, GO:0005743=TAS, GO:0004349=IDA, GO:0008652=TAS, GO:0044281=TAS, GO:0005524=IEA, GO:0005739=IDA, GO:0034641=TAS, GO:0004350=IDA, GO:0005737=IDA, GO:0006592=IMP, GO:0006561=IMP} L-proline biosynthetic process, cellular amino acid biosynthetic process, cellular nitrogen compound metabolic process, citrulline biosynthetic process, glutamate metabolic process, ornithine biosynthetic process, proline biosynthetic process, small molecule metabolic process cytoplasm, mitochondrial inner membrane, mitochondrion ATP binding, glutamate 5-kinase activity, glutamate-5-semialdehyde dehydrogenase activity Human ALDH1A1 InterPro UniProtKB {GO:0006805=Reactome:REACT_13705, GO:0001758=GO_REF:0000003, GO:0006069=Reactome:REACT_34, GO:0006081=PMID:1709013, GO:0004029=Reactome:REACT_2127, GO:0044281=Reactome:REACT_111217, GO:0005829=Reactome:REACT_2127, GO:0005099=PMID:1709013, GO:0005737=PMID:2987944, GO:0032320=PMID:1709013, GO:0042572=GO_REF:0000041, GO:0016491=GO_REF:0000002, GO:0005497=PMID:1709013} Q5SYQ9 Retinal dehydrogenase 1 protein 20130413 {GO:0006805=TAS, GO:0001758=IEA, GO:0006069=TAS, GO:0006081=TAS, GO:0004029=EXP, GO:0044281=TAS, GO:0005829=TAS, GO:0005099=TAS, GO:0005737=TAS, GO:0032320=TAS, GO:0042572=IEA, GO:0016491=IEA, GO:0005497=TAS} cellular aldehyde metabolic process, ethanol oxidation, positive regulation of Ras GTPase activity, retinol metabolic process, small molecule metabolic process, xenobiotic metabolic process cytoplasm, cytosol Ras GTPase activator activity, aldehyde dehydrogenase (NAD) activity, androgen binding, oxidoreductase activity, retinal dehydrogenase activity Human InterPro:IPR015590|InterPro:IPR016161|InterPro:IPR016162 ALDH1A2 HPA UniProtKB {GO:0048471=GO_REF:0000019, GO:0008284=GO_REF:0000019, GO:0008285=PMID:16166285, GO:0001758=GO_REF:0000024, GO:0071300=GO_REF:0000019, GO:0030324=GO_REF:0000019, GO:0033189=GO_REF:0000019, GO:0021983=GO_REF:0000019, GO:0016918=GO_REF:0000024, GO:0005634=GO_REF:0000052, GO:0009954=GO_REF:0000019, GO:0009952=GO_REF:0000019, GO:0005829=GO_REF:0000019, GO:0005737=GO_REF:0000052, GO:0031076=GO_REF:0000019, GO:0014032=GO_REF:0000019, GO:0042574=GO_REF:0000019, GO:0006776=PMID:8663198, GO:0042573=GO_REF:0000024, GO:0030182=GO_REF:0000019, GO:0042572=GO_REF:0000041, GO:0034097=PMID:18495959, GO:0032355=GO_REF:0000019, GO:0035799=GO_REF:0000019, GO:0043065=GO_REF:0000019, GO:0001568=GO_REF:0000019, GO:0001822=GO_REF:0000019, GO:0004028=GO_REF:0000024, GO:0048566=GO_REF:0000019, GO:0048384=GO_REF:0000019, GO:0048738=GO_REF:0000019, GO:0010628=GO_REF:0000019, GO:0001889=GO_REF:0000019, GO:0003007=GO_REF:0000019, GO:0016331=GO_REF:0000019, GO:0031016=GO_REF:0000019, GO:0007494=GO_REF:0000019, GO:0001936=GO_REF:0000019, GO:0016620=GO_REF:0000002, GO:0060324=GO_REF:0000019, GO:0042904=GO_REF:0000019, GO:0021915=PMID:16237707, GO:0035115=GO_REF:0000019, GO:0030902=GO_REF:0000019, GO:0009855=GO_REF:0000019} O94788 Retinal dehydrogenase 2 protein 20101115 {GO:0048471=IEA, GO:0008284=IEA, GO:0008285=IDA, GO:0001758=ISS, GO:0071300=IEA, GO:0030324=IEA, GO:0033189=IEA, GO:0021983=IEA, GO:0016918=ISS, GO:0005634=IDA, GO:0009954=IEA, GO:0009952=IEA, GO:0005829=IEA, GO:0005737=IDA, GO:0031076=IEA, GO:0014032=IEA, GO:0042574=IEA, GO:0006776=NAS, GO:0042573=ISS, GO:0030182=IEA, GO:0042572=IEA, GO:0034097=IDA, GO:0032355=IEA, GO:0035799=IEA, GO:0043065=IEA, GO:0001568=IEA, GO:0001822=IEA, GO:0004028=ISS, GO:0048566=IEA, GO:0048384=IEA, GO:0048738=IEA, GO:0010628=IEA, GO:0001889=IEA, GO:0003007=IEA, GO:0016331=IEA, GO:0031016=IEA, GO:0007494=IEA, GO:0001936=IEA, GO:0016620=IEA, GO:0060324=IEA, GO:0042904=IEA, GO:0021915=IMP, GO:0035115=IEA, GO:0030902=IEA, GO:0009855=IEA} 9-cis-retinoic acid biosynthetic process, anterior/posterior pattern specification, blood vessel development, cardiac muscle tissue development, cellular response to retinoic acid, determination of bilateral symmetry, embryonic camera-type eye development, embryonic digestive tract development, embryonic forelimb morphogenesis, face development, heart morphogenesis, hindbrain development, kidney development, liver development, lung development, midgut development, morphogenesis of embryonic epithelium, negative regulation of cell proliferation, neural crest cell development, neural tube development, neuron differentiation, pancreas development, pituitary gland development, positive regulation of apoptotic process, positive regulation of cell proliferation, positive regulation of gene expression, proximal/distal pattern formation, regulation of endothelial cell proliferation, response to cytokine stimulus, response to estradiol stimulus, response to vitamin A, retinal metabolic process, retinoic acid metabolic process, retinoic acid receptor signaling pathway, retinol metabolic process, ureter maturation, vitamin A metabolic process cytoplasm, cytosol, nucleus, perinuclear region of cytoplasm 3-chloroallyl aldehyde dehydrogenase activity, oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor, retinal binding, retinal dehydrogenase activity Human ALDH1A3 UniProtKB UniProtKB {GO:0043065=GO_REF:0000019, GO:0004029=GO_REF:0000019, GO:0070403=GO_REF:0000019, GO:0070324=GO_REF:0000019, GO:0042803=PMID:11585737, GO:0005737=PMID:11585737, GO:0042574=PMID:11585737, GO:0042573=PMID:11585737, GO:0016620=GO_REF:0000002, GO:0060324=GO_REF:0000019, GO:0042572=GO_REF:0000041, GO:0060166=GO_REF:0000019, GO:0016491=GO_REF:0000002, GO:0002072=GO_REF:0000019, GO:0002138=GO_REF:0000019, GO:0048048=GO_REF:0000024, GO:0004030=PMID:11585737, GO:0021768=GO_REF:0000019} P47895 Aldehyde dehydrogenase family 1 member A3 protein 20090316 {GO:0043065=IEA, GO:0004029=IEA, GO:0070403=IEA, GO:0070324=IEA, GO:0042803=IDA, GO:0005737=IDA, GO:0042574=IDA, GO:0042573=IDA, GO:0016620=IEA, GO:0060324=IEA, GO:0042572=IEA, GO:0060166=IEA, GO:0016491=IEA, GO:0002072=IEA, GO:0002138=IEA, GO:0048048=ISS, GO:0004030=IDA, GO:0021768=IEA} embryonic eye morphogenesis, face development, nucleus accumbens development, olfactory pit development, optic cup morphogenesis involved in camera-type eye development, positive regulation of apoptotic process, retinal metabolic process, retinoic acid biosynthetic process, retinoic acid metabolic process, retinol metabolic process cytoplasm "NAD+ binding, aldehyde dehydrogenase (NAD) activity, aldehyde dehydrogenase NAD(P)+"" activity, oxidoreductase activity, oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor, protein homodimerization activity, thyroid hormone binding""" Human UniProtKB:Q9JHW9 ALDH1B1 HPA UniProtKB {GO:0005739=GO_REF:0000052, GO:0005975=PMID:1306115, GO:0005759=GO_REF:0000039, GO:0006068=GO_REF:0000041, GO:0005730=GO_REF:0000052, GO:0004029=GO_REF:0000003, GO:0005634=GO_REF:0000052, GO:0043231=GO_REF:0000052} P30837 Aldehyde dehydrogenase X, mitochondrial protein 20101115 {GO:0005739=IDA, GO:0005975=NAS, GO:0005759=IEA, GO:0006068=IEA, GO:0005730=IDA, GO:0004029=IEA, GO:0005634=IDA, GO:0043231=IDA} carbohydrate metabolic process, ethanol catabolic process intracellular membrane-bounded organelle, mitochondrial matrix, mitochondrion, nucleolus, nucleus aldehyde dehydrogenase (NAD) activity Human ALDH1L1 InterPro UniProtKB {GO:0005739=GO_REF:0000019, GO:0016155=GO_REF:0000003, GO:0009058=GO_REF:0000002, GO:0016620=GO_REF:0000002, GO:0008168=GO_REF:0000002, GO:0016491=GO_REF:0000002, GO:0003824=PMID:10204077, GO:0016742=GO_REF:0000002, GO:0006730=GO_REF:0000037, GO:0009258=GO_REF:0000002} Q8TBP8 Cytosolic 10-formyltetrahydrofolate dehydrogenase protein 20130413 {GO:0005739=IEA, GO:0016155=IEA, GO:0009058=IEA, GO:0016620=IEA, GO:0008168=IEA, GO:0016491=IEA, GO:0003824=TAS, GO:0016742=IEA, GO:0006730=IEA, GO:0009258=IEA} 10-formyltetrahydrofolate catabolic process, biosynthetic process, one-carbon metabolic process mitochondrion catalytic activity, formyltetrahydrofolate dehydrogenase activity, hydroxymethyl-, formyl- and related transferase activity, methyltransferase activity, oxidoreductase activity, oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor Human InterPro:IPR002376|InterPro:IPR005793 ALDH1L2 HPA UniProtKB {GO:0005739=GO_REF:0000052, GO:0016155=GO_REF:0000003, GO:0009058=GO_REF:0000002, GO:0008168=GO_REF:0000002, GO:0016620=GO_REF:0000002, GO:0016742=GO_REF:0000002, GO:0006730=GO_REF:0000037, GO:0009258=GO_REF:0000002} Q3SY69 Mitochondrial 10-formyltetrahydrofolate dehydrogenase protein 20111111 {GO:0005739=IDA, GO:0016155=IEA, GO:0009058=IEA, GO:0008168=IEA, GO:0016620=IEA, GO:0016742=IEA, GO:0006730=IEA, GO:0009258=IEA} 10-formyltetrahydrofolate catabolic process, biosynthetic process, one-carbon metabolic process mitochondrion formyltetrahydrofolate dehydrogenase activity, hydroxymethyl-, formyl- and related transferase activity, methyltransferase activity, oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor Human ALDH2 Reactome UniProtKB {GO:0006805=Reactome:REACT_13705, GO:0005975=PMID:8903321, GO:0006066=PMID:1306115, GO:0006069=Reactome:REACT_34, GO:0006068=GO_REF:0000041, GO:0004029=Reactome:REACT_15407, GO:0009055=PMID:8903321, GO:0007268=Reactome:REACT_13685, GO:0044281=Reactome:REACT_111217, GO:0005759=Reactome:REACT_15407, GO:0016620=GO_REF:0000002, GO:0042136=Reactome:REACT_13583, GO:0004030=PMID:8903321} P05091 Aldehyde dehydrogenase, mitochondrial protein 20130213 {GO:0006805=TAS, GO:0005975=TAS, GO:0006066=TAS, GO:0006069=TAS, GO:0006068=IEA, GO:0004029=EXP, GO:0009055=TAS, GO:0007268=TAS, GO:0044281=TAS, GO:0005759=TAS, GO:0016620=IEA, GO:0042136=TAS, GO:0004030=TAS} alcohol metabolic process, carbohydrate metabolic process, ethanol catabolic process, ethanol oxidation, neurotransmitter biosynthetic process, small molecule metabolic process, synaptic transmission, xenobiotic metabolic process mitochondrial matrix "aldehyde dehydrogenase (NAD) activity, aldehyde dehydrogenase NAD(P)+"" activity, electron carrier activity, oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor""" Human ALDH3A1 LIFEdb UniProtKB {GO:0001666=GO_REF:0000019, GO:0008284=GO_REF:0000019, GO:0005783=GO_REF:0000054, GO:0007584=GO_REF:0000019, GO:0042493=GO_REF:0000019, GO:0007568=GO_REF:0000019, GO:0006081=PMID:1737758, GO:0004029=PMID:1737758, GO:0004028=GO_REF:0000019, GO:0051384=GO_REF:0000019, GO:0051591=GO_REF:0000019, GO:0005829=GO_REF:0000024, GO:0008106=PMID:1737758, GO:0055114=PMID:1737758, GO:0004030=GO_REF:0000003} P30838 Aldehyde dehydrogenase, dimeric NADP-preferring protein 20100607 {GO:0001666=IEA, GO:0008284=IEA, GO:0005783=IDA, GO:0007584=IEA, GO:0042493=IEA, GO:0007568=IEA, GO:0006081=IDA, GO:0004029=IDA, GO:0004028=IEA, GO:0051384=IEA, GO:0051591=IEA, GO:0005829=ISS, GO:0008106=IDA, GO:0055114=IDA, GO:0004030=IEA} aging, cellular aldehyde metabolic process, oxidation-reduction process, positive regulation of cell proliferation, response to cAMP, response to drug, response to glucocorticoid stimulus, response to hypoxia, response to nutrient cytosol, endoplasmic reticulum "3-chloroallyl aldehyde dehydrogenase activity, alcohol dehydrogenase (NADP+) activity, aldehyde dehydrogenase (NAD) activity, aldehyde dehydrogenase NAD(P)+"" activity""" Human ALDH3A2 UniProtKB UniProtKB {GO:0005783=GO_REF:0000019, GO:0006081=PMID:8528251, GO:0005743=GO_REF:0000019, GO:0004029=PMID:9133646, GO:0046577=PMID:18035827, GO:0007417=PMID:8528251, GO:0043231=PMID:9133646, GO:0008544=PMID:8528251, GO:0007422=PMID:8528251, GO:0005789=GO_REF:0000039, GO:0016021=GO_REF:0000037, GO:0033306=PMID:15110319, GO:0004030=GO_REF:0000002, GO:0055114=PMID:9133646} P51648 Fatty aldehyde dehydrogenase protein 20120416 {GO:0005783=IEA, GO:0006081=NAS, GO:0005743=IEA, GO:0004029=IDA, GO:0046577=IDA, GO:0007417=IMP, GO:0043231=IDA, GO:0008544=IMP, GO:0007422=IMP, GO:0005789=IEA, GO:0016021=IEA, GO:0033306=IMP, GO:0004030=IEA, GO:0055114=IDA} cellular aldehyde metabolic process, central nervous system development, epidermis development, oxidation-reduction process, peripheral nervous system development, phytol metabolic process endoplasmic reticulum, endoplasmic reticulum membrane, integral to membrane, intracellular membrane-bounded organelle, mitochondrial inner membrane "aldehyde dehydrogenase (NAD) activity, aldehyde dehydrogenase NAD(P)+"" activity, long-chain-alcohol oxidase activity""" Human ALDH3B1 MGI UniProtKB {GO:0006629=PMID:7828891, GO:0005737=PMID:20699116, GO:0006066=PMID:7828891, GO:0046185=PMID:20699116, GO:0006068=GO_REF:0000041, GO:0004028=PMID:7828891, GO:0034599=PMID:20699116, GO:0055114=PMID:20699116, GO:0004030=PMID:20699116} P43353 Aldehyde dehydrogenase family 3 member B1 protein 20120109 {GO:0006629=TAS, GO:0005737=IDA, GO:0006066=TAS, GO:0046185=IDA, GO:0006068=IEA, GO:0004028=TAS, GO:0034599=IDA, GO:0055114=IDA, GO:0004030=IDA} alcohol metabolic process, aldehyde catabolic process, cellular response to oxidative stress, ethanol catabolic process, lipid metabolic process, oxidation-reduction process cytoplasm "3-chloroallyl aldehyde dehydrogenase activity, aldehyde dehydrogenase NAD(P)+"" activity""" Human ALDH3B2 PINC UniProtKB {GO:0006629=PMID:8890755, GO:0006066=PMID:8890755, GO:0006068=GO_REF:0000041, GO:0006081=GO_REF:0000002, GO:0004028=PMID:8890755, GO:0004030=GO_REF:0000003} P48448 Aldehyde dehydrogenase family 3 member B2 protein 20030904 {GO:0006629=TAS, GO:0006066=TAS, GO:0006068=IEA, GO:0006081=IEA, GO:0004028=TAS, GO:0004030=IEA} alcohol metabolic process, cellular aldehyde metabolic process, ethanol catabolic process, lipid metabolic process "3-chloroallyl aldehyde dehydrogenase activity, aldehyde dehydrogenase NAD(P)+"" activity""" Human ALDH4A1 InterPro UniProtKB {GO:0004029=PMID:8621661, GO:0009055=PMID:8621661, GO:0044281=Reactome:REACT_111217, GO:0003842=Reactome:REACT_2180, GO:0042802=PMID:22516612, GO:0034641=Reactome:REACT_13, GO:0019470=PMID:21998747, GO:0006560=PMID:8621661, GO:0005759=Reactome:REACT_2180, GO:0016620=GO_REF:0000002, GO:0010133=GO_REF:0000041, GO:0016491=GO_REF:0000002, GO:0006562=Reactome:REACT_1002, GO:0006561=GO_REF:0000002} Q5TF55 Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial protein 20130413 {GO:0004029=TAS, GO:0009055=TAS, GO:0044281=TAS, GO:0003842=EXP, GO:0042802=IPI, GO:0034641=TAS, GO:0019470=TAS, GO:0006560=TAS, GO:0005759=TAS, GO:0016620=IEA, GO:0010133=IEA, GO:0016491=IEA, GO:0006562=TAS, GO:0006561=IEA} 4-hydroxyproline catabolic process, cellular nitrogen compound metabolic process, proline biosynthetic process, proline catabolic process, proline catabolic process to glutamate, proline metabolic process, small molecule metabolic process mitochondrial matrix 1-pyrroline-5-carboxylate dehydrogenase activity, aldehyde dehydrogenase (NAD) activity, electron carrier activity, identical protein binding, oxidoreductase activity, oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor Human InterPro:IPR015590|InterPro:IPR016161|InterPro:IPR016162 ALDH5A1 HPA UniProtKB {GO:0009013=GO_REF:0000002, GO:0004777=PMID:7814412, GO:0006536=GO_REF:0000024, GO:0046459=GO_REF:0000024, GO:0007268=Reactome:REACT_13685, GO:0006749=GO_REF:0000024, GO:0006083=GO_REF:0000024, GO:0007417=PMID:9683595, GO:0007269=Reactome:REACT_13723, GO:0006681=GO_REF:0000024, GO:0042803=PMID:16199352, GO:0022904=GO_REF:0000024, GO:0005739=GO_REF:0000052, GO:0051289=PMID:16199352, GO:0006105=GO_REF:0000024, GO:0005759=Reactome:REACT_24017, GO:0006006=GO_REF:0000024, GO:0006650=GO_REF:0000024, GO:0009450=PMID:15037717, GO:0042135=GO_REF:0000024, GO:0006541=GO_REF:0000024} P51649 Succinate-semialdehyde dehydrogenase, mitochondrial protein 20111111 {GO:0009013=IEA, GO:0004777=ISS, GO:0006536=ISS, GO:0046459=ISS, GO:0007268=TAS, GO:0006749=ISS, GO:0006083=ISS, GO:0007417=IMP, GO:0007269=TAS, GO:0006681=ISS, GO:0042803=IC, GO:0022904=ISS, GO:0005739=IDA, GO:0051289=IDA, GO:0006105=ISS, GO:0005759=TAS, GO:0006006=ISS, GO:0006650=ISS, GO:0009450=IMP, GO:0042135=ISS, GO:0006541=ISS} acetate metabolic process, central nervous system development, galactosylceramide metabolic process, gamma-aminobutyric acid catabolic process, glucose metabolic process, glutamate metabolic process, glutamine metabolic process, glutathione metabolic process, glycerophospholipid metabolic process, neurotransmitter catabolic process, neurotransmitter secretion, protein homotetramerization, respiratory electron transport chain, short-chain fatty acid metabolic process, succinate metabolic process, synaptic transmission mitochondrial matrix, mitochondrion "protein homodimerization activity, succinate-semialdehyde dehydrogenase (NAD+) activity, succinate-semialdehyde dehydrogenase NAD(P)+"" activity""" Human ALDH6A1 HPA UniProtKB {GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0019859=GO_REF:0000024, GO:0009083=Reactome:REACT_197, GO:0044281=Reactome:REACT_111217, GO:0005739=GO_REF:0000052, GO:0034641=Reactome:REACT_13, GO:0050873=GO_REF:0000019, GO:0005759=Reactome:REACT_1077, GO:0018478=GO_REF:0000024, GO:0006573=GO_REF:0000024, GO:0004491=GO_REF:0000024, GO:0000062=GO_REF:0000024} Q02252 "Methylmalonate-semialdehyde dehydrogenase ""acylating"", mitochondrial" protein 20101115 {GO:0005730=IDA, GO:0005634=IDA, GO:0019859=ISS, GO:0009083=TAS, GO:0044281=TAS, GO:0005739=IDA, GO:0034641=TAS, GO:0050873=IEA, GO:0005759=TAS, GO:0018478=ISS, GO:0006573=ISS, GO:0004491=ISS, GO:0000062=ISS} branched-chain amino acid catabolic process, brown fat cell differentiation, cellular nitrogen compound metabolic process, small molecule metabolic process, thymine metabolic process, valine metabolic process mitochondrial matrix, mitochondrion, nucleolus, nucleus fatty-acyl-CoA binding, malonate-semialdehyde dehydrogenase (acetylating) activity, methylmalonate-semialdehyde dehydrogenase (acylating) activity Human ALDH7A1 HPA UniProtKB {GO:0005515=PMID:21988832, GO:0007605=PMID:9417906, GO:0019285=GO_REF:0000041, GO:0004029=GO_REF:0000024, GO:0006081=GO_REF:0000024, GO:0005634=GO_REF:0000039, GO:0044281=Reactome:REACT_111217, GO:0005829=GO_REF:0000039, GO:0005739=GO_REF:0000052, GO:0034641=Reactome:REACT_13, GO:0005737=GO_REF:0000052, GO:0008802=GO_REF:0000003, GO:0005759=Reactome:REACT_1540, GO:0016620=GO_REF:0000002, GO:0016491=GO_REF:0000002, GO:0006554=Reactome:REACT_1298, GO:0004043=Reactome:REACT_1540} P49419 Alpha-aminoadipic semialdehyde dehydrogenase protein 20100326 {GO:0005515=IPI, GO:0007605=TAS, GO:0019285=IEA, GO:0004029=ISS, GO:0006081=ISS, GO:0005634=IEA, GO:0044281=TAS, GO:0005829=IEA, GO:0005739=IDA, GO:0034641=TAS, GO:0005737=IDA, GO:0008802=IEA, GO:0005759=TAS, GO:0016620=IEA, GO:0016491=IEA, GO:0006554=TAS, GO:0004043=EXP} cellular aldehyde metabolic process, cellular nitrogen compound metabolic process, glycine betaine biosynthetic process from choline, lysine catabolic process, sensory perception of sound, small molecule metabolic process cytoplasm, cytosol, mitochondrial matrix, mitochondrion, nucleus L-aminoadipate-semialdehyde dehydrogenase activity, aldehyde dehydrogenase (NAD) activity, betaine-aldehyde dehydrogenase activity, oxidoreductase activity, oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor, protein binding Human ALDH8A1 UniProtKB UniProtKB {GO:0005622=PMID:11007799, GO:0005737=GO_REF:0000039, GO:0001758=PMID:11007799, GO:0042574=PMID:11007799, GO:0042573=PMID:11007799, GO:0042904=GO_REF:0000019, GO:0016620=GO_REF:0000002} Q9H2A2 Aldehyde dehydrogenase family 8 member A1 protein 20031216 {GO:0005622=IDA, GO:0005737=IEA, GO:0001758=IDA, GO:0042574=IDA, GO:0042573=IDA, GO:0042904=IEA, GO:0016620=IEA} 9-cis-retinoic acid biosynthetic process, retinal metabolic process, retinoic acid metabolic process cytoplasm, intracellular oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor, retinal dehydrogenase activity Human ALDH9A1 HPA UniProtKB {GO:0005886=GO_REF:0000052, GO:0006081=PMID:8645224, GO:0004029=PMID:2925663, GO:0004028=Reactome:REACT_220, GO:0044281=Reactome:REACT_111217, GO:0005829=Reactome:REACT_220, GO:0005739=GO_REF:0000019, GO:0034641=Reactome:REACT_13, GO:0005737=GO_REF:0000052, GO:0047105=GO_REF:0000003, GO:0016620=GO_REF:0000019, GO:0045329=Reactome:REACT_2125, GO:0019145=PMID:8645224, GO:0042445=PMID:2925663, GO:0033737=GO_REF:0000003, GO:0042136=PMID:2925663, GO:0009437=GO_REF:0000019, GO:0055114=PMID:2925663} P49189 4-trimethylaminobutyraldehyde dehydrogenase protein 20101115 {GO:0005886=IDA, GO:0006081=IDA, GO:0004029=IDA, GO:0004028=TAS, GO:0044281=TAS, GO:0005829=TAS, GO:0005739=IEA, GO:0034641=TAS, GO:0005737=IDA, GO:0047105=IEA, GO:0016620=IEA, GO:0045329=TAS, GO:0019145=IDA, GO:0042445=TAS, GO:0033737=IEA, GO:0042136=IDA, GO:0009437=IEA, GO:0055114=IDA} carnitine biosynthetic process, carnitine metabolic process, cellular aldehyde metabolic process, cellular nitrogen compound metabolic process, hormone metabolic process, neurotransmitter biosynthetic process, oxidation-reduction process, small molecule metabolic process cytoplasm, cytosol, mitochondrion, plasma membrane 1-pyrroline dehydrogenase activity, 3-chloroallyl aldehyde dehydrogenase activity, 4-trimethylammoniobutyraldehyde dehydrogenase activity, aldehyde dehydrogenase (NAD) activity, aminobutyraldehyde dehydrogenase activity, oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor Human ALDOA BHF-UCL UniProtKB {GO:0008092=PMID:9244396, GO:0008360=PMID:9244396, GO:0006094=Reactome:REACT_1520, GO:0006941=PMID:14615364, GO:0044281=Reactome:REACT_111217, GO:0015629=PMID:9244396, GO:0006096=PMID:14615364, GO:0046716=PMID:14615364, GO:0005829=Reactome:REACT_1602, GO:0042802=PMID:14766013, GO:0004332=PMID:9244396, GO:0006754=PMID:14615364, GO:0015631=PMID:17329259, GO:0051289=GO_REF:0000024, GO:0006006=Reactome:REACT_723, GO:0007015=PMID:1008835, GO:0031093=Reactome:REACT_21351, GO:0070061=PMID:14766013, GO:0006000=PMID:14615364, GO:0070062=PMID:17641064, GO:0005975=Reactome:REACT_474, GO:0030168=Reactome:REACT_798, GO:0005576=Reactome:REACT_21351, GO:0003779=PMID:1008835, GO:0030388=PMID:9244396, GO:0007596=Reactome:REACT_604, GO:0002576=Reactome:REACT_318, GO:0031674=PMID:1008835} P04075 Fructose-bisphosphate aldolase A protein 20081006 {GO:0008092=IDA, GO:0008360=IDA, GO:0006094=TAS, GO:0006941=IMP, GO:0044281=TAS, GO:0015629=IDA, GO:0006096=IMP, GO:0046716=IMP, GO:0005829=TAS, GO:0042802=TAS, GO:0004332=IDA, GO:0006754=IMP, GO:0015631=TAS, GO:0051289=ISS, GO:0006006=TAS, GO:0007015=TAS, GO:0031093=TAS, GO:0070061=IDA, GO:0006000=IMP, GO:0070062=IDA, GO:0005975=TAS, GO:0030168=TAS, GO:0005576=TAS, GO:0003779=TAS, GO:0030388=IDA, GO:0007596=TAS, GO:0002576=TAS, GO:0031674=TAS} ATP biosynthetic process, actin filament organization, blood coagulation, carbohydrate metabolic process, fructose 1,6-bisphosphate metabolic process, fructose metabolic process, gluconeogenesis, glucose metabolic process, glycolysis, muscle cell homeostasis, platelet activation, platelet degranulation, protein homotetramerization, regulation of cell shape, small molecule metabolic process, striated muscle contraction I band, actin cytoskeleton, cytosol, extracellular region, extracellular vesicular exosome, platelet alpha granule lumen actin binding, cytoskeletal protein binding, fructose binding, fructose-bisphosphate aldolase activity, identical protein binding, tubulin binding Human ALDOB InterPro UniProtKB {GO:0008092=PMID:9244396, GO:0005515=PMID:18000879, GO:0070072=PMID:17576770, GO:0005815=PMID:18000879, GO:0005975=Reactome:REACT_474, GO:0034451=PMID:18000879, GO:0006094=Reactome:REACT_1520, GO:0044281=Reactome:REACT_111217, GO:0032781=PMID:17576770, GO:0006096=GO_REF:0000002, GO:0042802=PMID:10625657, GO:0005829=Reactome:REACT_2013, GO:0004332=GO_REF:0000002, GO:0030388=PMID:10625657, GO:0006116=PMID:17576770, GO:0051117=PMID:17576770, GO:0006006=Reactome:REACT_723, GO:0070061=PMID:10625657, GO:0006001=Reactome:REACT_1571, GO:0006000=PMID:3383242} Q5T7D5 Fructose-bisphosphate aldolase B protein 20130413 {GO:0008092=IDA, GO:0005515=IPI, GO:0070072=IGI, GO:0005815=IDA, GO:0005975=TAS, GO:0034451=IDA, GO:0006094=TAS, GO:0044281=TAS, GO:0032781=IGI, GO:0006096=IEA, GO:0042802=IPI, GO:0005829=TAS, GO:0004332=IEA, GO:0030388=IDA, GO:0006116=IDA, GO:0051117=IDA, GO:0006006=TAS, GO:0070061=IMP, GO:0006001=TAS, GO:0006000=IMP} NADH oxidation, carbohydrate metabolic process, fructose 1,6-bisphosphate metabolic process, fructose catabolic process, fructose metabolic process, gluconeogenesis, glucose metabolic process, glycolysis, positive regulation of ATPase activity, small molecule metabolic process, vacuolar proton-transporting V-type ATPase complex assembly centriolar satellite, cytosol, microtubule organizing center ATPase binding, cytoskeletal protein binding, fructose binding, fructose-bisphosphate aldolase activity, identical protein binding, protein binding Human InterPro:IPR000741 ALDOC BHF-UCL UniProtKB {GO:0008092=PMID:9244396, GO:0005515=PMID:11399750, GO:0001666=GO_REF:0000019, GO:0014070=GO_REF:0000019, GO:0030424=GO_REF:0000019, GO:0005975=Reactome:REACT_474, GO:0007568=GO_REF:0000019, GO:0031100=GO_REF:0000019, GO:0006094=Reactome:REACT_1520, GO:0006915=GO_REF:0000019, GO:0010243=GO_REF:0000019, GO:0051290=GO_REF:0000019, GO:0044281=Reactome:REACT_111217, GO:0006096=Reactome:REACT_1383, GO:0005829=Reactome:REACT_1602, GO:0005739=GO_REF:0000019, GO:0004332=PMID:9244396, GO:0030388=PMID:9244396, GO:0051289=GO_REF:0000019, GO:0006006=Reactome:REACT_723, GO:0005856=PMID:9244396, GO:0006000=PMID:3105602} P09972 Fructose-bisphosphate aldolase C protein 20081007 {GO:0008092=IDA, GO:0005515=IPI, GO:0001666=IEA, GO:0014070=IEA, GO:0030424=IEA, GO:0005975=TAS, GO:0007568=IEA, GO:0031100=IEA, GO:0006094=TAS, GO:0006915=IEA, GO:0010243=IEA, GO:0051290=IEA, GO:0044281=TAS, GO:0006096=TAS, GO:0005829=TAS, GO:0005739=IEA, GO:0004332=IDA, GO:0030388=IDA, GO:0051289=IEA, GO:0006006=TAS, GO:0005856=IC, GO:0006000=TAS} aging, apoptotic process, carbohydrate metabolic process, fructose 1,6-bisphosphate metabolic process, fructose metabolic process, gluconeogenesis, glucose metabolic process, glycolysis, organ regeneration, protein heterotetramerization, protein homotetramerization, response to hypoxia, response to organic cyclic compound, response to organic nitrogen, small molecule metabolic process axon, cytoskeleton, cytosol, mitochondrion cytoskeletal protein binding, fructose-bisphosphate aldolase activity, protein binding Human ALG1 Reactome UniProtKB {GO:0000030=PMID:10704531, GO:0005783=PMID:10704531, GO:0016757=GO_REF:0000002, GO:0005789=Reactome:REACT_22214, GO:0004578=GO_REF:0000003, GO:0006486=PMID:10704531, GO:0016021=GO_REF:0000037, GO:0006488=Reactome:REACT_22433, GO:0044267=Reactome:REACT_17015, GO:0009103=PMID:10704531, GO:0043687=Reactome:REACT_22161, GO:0018279=Reactome:REACT_22426} Q9BT22 Chitobiosyldiphosphodolichol beta-mannosyltransferase protein 20130301 {GO:0000030=TAS, GO:0005783=TAS, GO:0016757=IEA, GO:0005789=TAS, GO:0004578=IEA, GO:0006486=TAS, GO:0016021=IEA, GO:0006488=TAS, GO:0044267=TAS, GO:0009103=TAS, GO:0043687=TAS, GO:0018279=TAS} cellular protein metabolic process, dolichol-linked oligosaccharide biosynthetic process, lipopolysaccharide biosynthetic process, post-translational protein modification, protein N-linked glycosylation via asparagine, protein glycosylation endoplasmic reticulum, endoplasmic reticulum membrane, integral to membrane chitobiosyldiphosphodolichol beta-mannosyltransferase activity, mannosyltransferase activity, transferase activity, transferring glycosyl groups Human ALG10 Reactome UniProtKB {GO:0016758=GO_REF:0000002, GO:0005789=GO_REF:0000039, GO:0016021=GO_REF:0000037, GO:0006488=Reactome:REACT_22433, GO:0044267=Reactome:REACT_17015, GO:0043687=Reactome:REACT_22161, GO:0018279=Reactome:REACT_22426} Q5BKT4 Dol-P-Glc:Glc(2)Man(9)GlcNAc(2)-PP-Dol alpha-1,2-glucosyltransferase protein 20130301 {GO:0016758=IEA, GO:0005789=IEA, GO:0016021=IEA, GO:0006488=TAS, GO:0044267=TAS, GO:0043687=TAS, GO:0018279=TAS} cellular protein metabolic process, dolichol-linked oligosaccharide biosynthetic process, post-translational protein modification, protein N-linked glycosylation via asparagine endoplasmic reticulum membrane, integral to membrane transferase activity, transferring hexosyl groups Human ALG10B Reactome UniProtKB {GO:0005886=GO_REF:0000039, GO:0016758=GO_REF:0000002, GO:0016021=GO_REF:0000037, GO:0006488=Reactome:REACT_22433, GO:0044267=Reactome:REACT_17015, GO:0043687=Reactome:REACT_22161, GO:0018279=Reactome:REACT_22426} Q5I7T1 Putative Dol-P-Glc:Glc(2)Man(9)GlcNAc(2)-PP-Dol alpha-1,2-glucosyltransferase protein 20130301 {GO:0005886=IEA, GO:0016758=IEA, GO:0016021=IEA, GO:0006488=TAS, GO:0044267=TAS, GO:0043687=TAS, GO:0018279=TAS} cellular protein metabolic process, dolichol-linked oligosaccharide biosynthetic process, post-translational protein modification, protein N-linked glycosylation via asparagine integral to membrane, plasma membrane transferase activity, transferring hexosyl groups Human ALG11 Reactome UniProtKB {GO:0005789=GO_REF:0000039, GO:0004377=GO_REF:0000003, GO:0016021=GO_REF:0000037, GO:0006488=Reactome:REACT_22433, GO:0044267=Reactome:REACT_17015, GO:0043687=Reactome:REACT_22161, GO:0018279=Reactome:REACT_22426} Q2TAA5 GDP-Man:Man(3)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase protein 20130301 {GO:0005789=IEA, GO:0004377=IEA, GO:0016021=IEA, GO:0006488=TAS, GO:0044267=TAS, GO:0043687=TAS, GO:0018279=TAS} cellular protein metabolic process, dolichol-linked oligosaccharide biosynthetic process, post-translational protein modification, protein N-linked glycosylation via asparagine endoplasmic reticulum membrane, integral to membrane GDP-Man:Man3GlcNAc2-PP-Dol alpha-1,2-mannosyltransferase activity Human ALG12 Reactome UniProtKB {GO:0016757=GO_REF:0000002, GO:0005783=PMID:12217961, GO:0031227=GO_REF:0000002, GO:0006457=PMID:12217961, GO:0000009=PMID:12217961, GO:0005789=Reactome:REACT_22117, GO:0016021=GO_REF:0000037, GO:0006487=PMID:12217961, GO:0006488=Reactome:REACT_22433, GO:0044267=Reactome:REACT_17015, GO:0006506=GO_REF:0000002, GO:0018279=Reactome:REACT_22426, GO:0043687=Reactome:REACT_22161, GO:0052917=GO_REF:0000003} Q9BV10 Dol-P-Man:Man(7)GlcNAc(2)-PP-Dol alpha-1,6-mannosyltransferase protein 20130301 {GO:0016757=IEA, GO:0005783=NAS, GO:0031227=IEA, GO:0006457=NAS, GO:0000009=IC, GO:0005789=TAS, GO:0016021=IEA, GO:0006487=IGI, GO:0006488=TAS, GO:0044267=TAS, GO:0006506=IEA, GO:0018279=TAS, GO:0043687=TAS, GO:0052917=IEA} GPI anchor biosynthetic process, cellular protein metabolic process, dolichol-linked oligosaccharide biosynthetic process, post-translational protein modification, protein N-linked glycosylation, protein N-linked glycosylation via asparagine, protein folding endoplasmic reticulum, endoplasmic reticulum membrane, integral to membrane, intrinsic to endoplasmic reticulum membrane alpha-1,6-mannosyltransferase activity, dol-P-Man:Man(7)GlcNAc(2)-PP-Dol alpha-1,6-mannosyltransferase activity, transferase activity, transferring glycosyl groups Human ALG13 Reactome UniProtKB {GO:0004577=GO_REF:0000003, GO:0016758=GO_REF:0000002, GO:0005789=Reactome:REACT_22332, GO:0030246=GO_REF:0000002, GO:0006488=Reactome:REACT_22433, GO:0044267=Reactome:REACT_17015, GO:0030259=GO_REF:0000002, GO:0043687=Reactome:REACT_22161, GO:0018279=Reactome:REACT_22426} Q9NP73 UDP-N-acetylglucosamine transferase subunit ALG13 homolog protein 20130301 {GO:0004577=IEA, GO:0016758=IEA, GO:0005789=TAS, GO:0030246=IEA, GO:0006488=TAS, GO:0044267=TAS, GO:0030259=IEA, GO:0043687=TAS, GO:0018279=TAS} cellular protein metabolic process, dolichol-linked oligosaccharide biosynthetic process, lipid glycosylation, post-translational protein modification, protein N-linked glycosylation via asparagine endoplasmic reticulum membrane N-acetylglucosaminyldiphosphodolichol N-acetylglucosaminyltransferase activity, carbohydrate binding, transferase activity, transferring hexosyl groups Human ALG14 Reactome UniProtKB {GO:0005789=Reactome:REACT_22332, GO:0016021=GO_REF:0000037, GO:0006488=Reactome:REACT_22433, GO:0044267=Reactome:REACT_17015, GO:0043687=Reactome:REACT_22161, GO:0018279=Reactome:REACT_22426} Q96F25 UDP-N-acetylglucosamine transferase subunit ALG14 homolog protein 20130301 {GO:0005789=TAS, GO:0016021=IEA, GO:0006488=TAS, GO:0044267=TAS, GO:0043687=TAS, GO:0018279=TAS} cellular protein metabolic process, dolichol-linked oligosaccharide biosynthetic process, post-translational protein modification, protein N-linked glycosylation via asparagine endoplasmic reticulum membrane, integral to membrane Human ALG1L UniProtKB UniProtKB {GO:0016757=GO_REF:0000037} Q6GMV1 Putative glycosyltransferase ALG1-like protein 20130413 {GO:0016757=IEA} transferase activity, transferring glycosyl groups Human UniProtKB-KW:KW-0328 ALG2 Reactome UniProtKB {GO:0005515=PMID:11883939, GO:0048471=PMID:17196169, GO:0000033=PMID:12684507, GO:0046982=PMID:11278427, GO:0033164=GO_REF:0000002, GO:0005634=PMID:17196169, GO:0004378=GO_REF:0000003, GO:0033577=PMID:12684507, GO:0051592=PMID:17196169, GO:0005737=PMID:17196169, GO:0047485=PMID:12445460, GO:0016020=PMID:16996505, GO:0005789=Reactome:REACT_22347, GO:0016021=GO_REF:0000037, GO:0006488=Reactome:REACT_22433, GO:0043495=PMID:16957052, GO:0044267=Reactome:REACT_17015, GO:0043687=Reactome:REACT_22161, GO:0018279=Reactome:REACT_22426, GO:0048306=PMID:14999017} Q9H553 Alpha-1,3/1,6-mannosyltransferase ALG2 protein 20130301 {GO:0005515=IPI, GO:0048471=IDA, GO:0000033=IDA, GO:0046982=IPI, GO:0033164=IEA, GO:0005634=IDA, GO:0004378=IEA, GO:0033577=IGI, GO:0051592=IDA, GO:0005737=IDA, GO:0047485=IPI, GO:0016020=IDA, GO:0005789=TAS, GO:0016021=IEA, GO:0006488=TAS, GO:0043495=IMP, GO:0044267=TAS, GO:0043687=TAS, GO:0018279=TAS, GO:0048306=IMP} cellular protein metabolic process, dolichol-linked oligosaccharide biosynthetic process, post-translational protein modification, protein N-linked glycosylation via asparagine, protein glycosylation in endoplasmic reticulum, response to calcium ion cytoplasm, endoplasmic reticulum membrane, integral to membrane, membrane, nucleus, perinuclear region of cytoplasm GDP-Man:Man1GlcNAc2-PP-Dol alpha-1,3-mannosyltransferase activity, alpha-1,3-mannosyltransferase activity, calcium-dependent protein binding, glycolipid 6-alpha-mannosyltransferase activity, protein N-terminus binding, protein anchor, protein binding, protein heterodimerization activity Human ALG3 Reactome UniProtKB {GO:0052925=GO_REF:0000003, GO:0000033=PMID:10581255, GO:0016758=GO_REF:0000002, GO:0005783=GO_REF:0000002, GO:0005789=Reactome:REACT_22415, GO:0006486=PMID:10581255, GO:0016021=GO_REF:0000037, GO:0006488=Reactome:REACT_22433, GO:0044267=Reactome:REACT_17015, GO:0043687=Reactome:REACT_22161, GO:0018279=Reactome:REACT_22426} Q92685 Dol-P-Man:Man(5)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase protein 20130301 {GO:0052925=IEA, GO:0000033=IDA, GO:0016758=IEA, GO:0005783=IEA, GO:0005789=TAS, GO:0006486=NAS, GO:0016021=IEA, GO:0006488=TAS, GO:0044267=TAS, GO:0043687=TAS, GO:0018279=TAS} cellular protein metabolic process, dolichol-linked oligosaccharide biosynthetic process, post-translational protein modification, protein N-linked glycosylation via asparagine, protein glycosylation endoplasmic reticulum, endoplasmic reticulum membrane, integral to membrane alpha-1,3-mannosyltransferase activity, dol-P-Man:Man(5)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase activity, transferase activity, transferring hexosyl groups Human ALG5 Reactome UniProtKB {GO:0004576=PMID:10359825, GO:0004581=GO_REF:0000003, GO:0007368=GO_REF:0000019, GO:0016757=GO_REF:0000038, GO:0005789=Reactome:REACT_22143, GO:0006486=PMID:10359825, GO:0016021=GO_REF:0000037, GO:0006488=Reactome:REACT_22433, GO:0044267=Reactome:REACT_17015, GO:0043687=Reactome:REACT_22161, GO:0018279=Reactome:REACT_22426} Q9Y673 Dolichyl-phosphate beta-glucosyltransferase protein 20130301 {GO:0004576=TAS, GO:0004581=IEA, GO:0007368=IEA, GO:0016757=IEA, GO:0005789=TAS, GO:0006486=TAS, GO:0016021=IEA, GO:0006488=TAS, GO:0044267=TAS, GO:0043687=TAS, GO:0018279=TAS} cellular protein metabolic process, determination of left/right symmetry, dolichol-linked oligosaccharide biosynthetic process, post-translational protein modification, protein N-linked glycosylation via asparagine, protein glycosylation endoplasmic reticulum membrane, integral to membrane dolichyl-phosphate beta-glucosyltransferase activity, oligosaccharyl transferase activity, transferase activity, transferring glycosyl groups Human ALG8 Reactome UniProtKB {GO:0000033=PMID:12480927, GO:0016758=GO_REF:0000002, GO:0005789=Reactome:REACT_22158, GO:0006487=PMID:12480927, GO:0016021=GO_REF:0000037, GO:0006488=Reactome:REACT_22433, GO:0044267=Reactome:REACT_17015, GO:0043687=Reactome:REACT_22161, GO:0018279=Reactome:REACT_22426} Q9BVK2 Probable dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glucosyltransferase protein 20130301 {GO:0000033=IMP, GO:0016758=IEA, GO:0005789=TAS, GO:0006487=IMP, GO:0016021=IEA, GO:0006488=TAS, GO:0044267=TAS, GO:0043687=TAS, GO:0018279=TAS} cellular protein metabolic process, dolichol-linked oligosaccharide biosynthetic process, post-translational protein modification, protein N-linked glycosylation, protein N-linked glycosylation via asparagine endoplasmic reticulum membrane, integral to membrane alpha-1,3-mannosyltransferase activity, transferase activity, transferring hexosyl groups Human ALG9 Reactome UniProtKB {GO:0052926=GO_REF:0000003, GO:0016757=GO_REF:0000002, GO:0005789=Reactome:REACT_22307, GO:0031227=GO_REF:0000002, GO:0016021=GO_REF:0000037, GO:0006488=Reactome:REACT_22433, GO:0044267=Reactome:REACT_17015, GO:0052918=GO_REF:0000003, GO:0006506=GO_REF:0000002, GO:0043687=Reactome:REACT_22161, GO:0018279=Reactome:REACT_22426} Q9H6U8 Alpha-1,2-mannosyltransferase ALG9 protein 20130301 {GO:0052926=IEA, GO:0016757=IEA, GO:0005789=TAS, GO:0031227=IEA, GO:0016021=IEA, GO:0006488=TAS, GO:0044267=TAS, GO:0052918=IEA, GO:0006506=IEA, GO:0043687=TAS, GO:0018279=TAS} GPI anchor biosynthetic process, cellular protein metabolic process, dolichol-linked oligosaccharide biosynthetic process, post-translational protein modification, protein N-linked glycosylation via asparagine endoplasmic reticulum membrane, integral to membrane, intrinsic to endoplasmic reticulum membrane dol-P-Man:Man(6)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase activity, dol-P-Man:Man(8)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase activity, transferase activity, transferring glycosyl groups Human ALK GOC UniProtKB {GO:0005515=PMID:22939624, GO:0008283=PMID:19459784, GO:0042981=PMID:19459784, GO:0005524=GO_REF:0000037, GO:0038061=PMID:19459784, GO:0000187=PMID:19459784, GO:0016310=PMID:19459784, GO:0007165=PMID:19459784, GO:0004704=PMID:19459784, GO:0046777=PMID:19459784, GO:0051092=PMID:19459784, GO:0048666=PMID:19459784, GO:0005887=PMID:19459784, GO:0004714=PMID:19459784, GO:0007169=GO_REF:0000002} Q9UM73 ALK tyrosine kinase receptor protein 20130413 {GO:0005515=IPI, GO:0008283=TAS, GO:0042981=TAS, GO:0005524=IEA, GO:0038061=TAS, GO:0000187=TAS, GO:0016310=TAS, GO:0007165=TAS, GO:0004704=TAS, GO:0046777=TAS, GO:0051092=TAS, GO:0048666=TAS, GO:0005887=TAS, GO:0004714=TAS, GO:0007169=IEA} NIK/NF-kappaB cascade, activation of MAPK activity, cell proliferation, neuron development, phosphorylation, positive regulation of NF-kappaB transcription factor activity, protein autophosphorylation, regulation of apoptotic process, signal transduction, transmembrane receptor protein tyrosine kinase signaling pathway integral to plasma membrane ATP binding, NF-kappaB-inducing kinase activity, protein binding, transmembrane receptor protein tyrosine kinase activity Human ALKBH1 UniProtKB UniProtKB {GO:0003906=PMID:19959401, GO:0005719=GO_REF:0000019, GO:0070989=PMID:18603530, GO:0042245=PMID:18603530, GO:0001890=GO_REF:0000019, GO:0001701=GO_REF:0000019, GO:0042056=GO_REF:0000019, GO:0031175=GO_REF:0000019, GO:0008198=PMID:18603530, GO:0005739=PMID:18603530, GO:0043524=GO_REF:0000019, GO:0006307=PMID:18603530, GO:0006281=PMID:19959401, GO:0048589=GO_REF:0000019, GO:0080111=PMID:18603530, GO:0070579=PMID:18603530, GO:0016702=GO_REF:0000037, GO:0001764=GO_REF:0000019} Q13686 Alkylated DNA repair protein alkB homolog 1 protein 20100429 {GO:0003906=IDA, GO:0005719=IEA, GO:0070989=IDA, GO:0042245=IDA, GO:0001890=IEA, GO:0001701=IEA, GO:0042056=IEA, GO:0031175=IEA, GO:0008198=IDA, GO:0005739=IDA, GO:0043524=IEA, GO:0006307=IDA, GO:0006281=IDA, GO:0048589=IEA, GO:0080111=IDA, GO:0070579=IDA, GO:0016702=IEA, GO:0001764=IEA} DNA dealkylation involved in DNA repair, DNA demethylation, DNA repair, RNA repair, developmental growth, in utero embryonic development, negative regulation of neuron apoptotic process, neuron migration, neuron projection development, oxidative demethylation, placenta development mitochondrion, nuclear euchromatin DNA-(apurinic or apyrimidinic site) lyase activity, chemoattractant activity, ferrous iron binding, methylcytosine dioxygenase activity, oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen Human ALKBH2 BHF-UCL UniProtKB {GO:0006281=Reactome:REACT_216, GO:0006307=PMID:18775698, GO:0070989=PMID:18775698, GO:0080111=PMID:18775698, GO:0035511=PMID:18432238, GO:0043734=PMID:18432238, GO:0016706=GO_REF:0000019, GO:0005654=Reactome:REACT_2185, GO:0016702=GO_REF:0000037, GO:0051747=PMID:18775698, GO:0008198=PMID:18432238} Q6NS38 Alpha-ketoglutarate-dependent dioxygenase alkB homolog 2 protein 20100115 {GO:0006281=TAS, GO:0006307=TAS, GO:0070989=TAS, GO:0080111=TAS, GO:0035511=IDA, GO:0043734=IDA, GO:0016706=IEA, GO:0005654=TAS, GO:0016702=IEA, GO:0051747=TAS, GO:0008198=IDA} DNA dealkylation involved in DNA repair, DNA demethylation, DNA repair, oxidative DNA demethylation, oxidative demethylation nucleoplasm DNA-N1-methyladenine dioxygenase activity, cytosine C-5 DNA demethylase activity, ferrous iron binding, oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors, oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen Human ALKBH3 HPA UniProtKB {GO:0005515=PMID:22055184, GO:0031418=GO_REF:0000037, GO:0008283=PMID:22055184, GO:0043734=PMID:22055184, GO:0005634=GO_REF:0000052, GO:0008198=PMID:16858410, GO:0035552=PMID:22055184, GO:0005739=GO_REF:0000052, GO:0005737=GO_REF:0000052, GO:0006307=Reactome:REACT_2020, GO:0006281=Reactome:REACT_216, GO:0016706=GO_REF:0000002, GO:0005654=Reactome:REACT_1934, GO:0016702=GO_REF:0000037, GO:0051747=GO_REF:0000019} Q96Q83 Alpha-ketoglutarate-dependent dioxygenase alkB homolog 3 protein 20101115 {GO:0005515=IPI, GO:0031418=IEA, GO:0008283=IMP, GO:0043734=IMP, GO:0005634=IDA, GO:0008198=IDA, GO:0035552=IMP, GO:0005739=IDA, GO:0005737=IDA, GO:0006307=TAS, GO:0006281=TAS, GO:0016706=IEA, GO:0005654=TAS, GO:0016702=IEA, GO:0051747=IEA} DNA dealkylation involved in DNA repair, DNA repair, cell proliferation, oxidative single-stranded DNA demethylation cytoplasm, mitochondrion, nucleoplasm, nucleus DNA-N1-methyladenine dioxygenase activity, L-ascorbic acid binding, cytosine C-5 DNA demethylase activity, ferrous iron binding, oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors, oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen, protein binding Human ALKBH5 UniProtKB UniProtKB {GO:0006397=PMID:23177736, GO:0001666=PMID:21264265, GO:0006406=PMID:23177736, GO:0016607=PMID:23177736, GO:0016706=PMID:21264265, GO:0005634=PMID:21264265, GO:0007283=GO_REF:0000024, GO:0035515=PMID:23177736, GO:0016702=GO_REF:0000037, GO:0035553=PMID:23177736, GO:0046872=GO_REF:0000037, GO:0030154=GO_REF:0000037} Q6P6C2 RNA demethylase ALKBH5 protein 20130118 {GO:0006397=IMP, GO:0001666=IDA, GO:0006406=IMP, GO:0016607=IDA, GO:0016706=IDA, GO:0005634=IDA, GO:0007283=ISS, GO:0035515=IDA, GO:0016702=IEA, GO:0035553=IDA, GO:0046872=IEA, GO:0030154=IEA} cell differentiation, mRNA export from nucleus, mRNA processing, oxidative single-stranded RNA demethylation, response to hypoxia, spermatogenesis nuclear speck, nucleus metal ion binding, oxidative RNA demethylase activity, oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors, oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen Human UniProtKB:Q3TSG4 ALKBH7 UniProtKB UniProtKB {GO:0005739=GO_REF:0000019, GO:0005634=GO_REF:0000039, GO:0005576=GO_REF:0000039, GO:0016702=GO_REF:0000037, GO:0046872=GO_REF:0000037} Q9BT30 Alpha-ketoglutarate-dependent dioxygenase alkB homolog 7 protein 20130413 {GO:0005739=IEA, GO:0005634=IEA, GO:0005576=IEA, GO:0016702=IEA, GO:0046872=IEA} extracellular region, mitochondrion, nucleus metal ion binding, oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen Human UniProtKB-SubCell:SL-0191 ALMS1 HPA UniProtKB {GO:0001736=GO_REF:0000019, GO:0019722=GO_REF:0000019, GO:0060122=GO_REF:0000019, GO:0045598=GO_REF:0000019, GO:0007605=GO_REF:0000019, GO:0051492=PMID:22693585, GO:0007286=GO_REF:0000019, GO:0005829=Reactome:REACT_15470, GO:0003674=GO_REF:0000015, GO:0005737=GO_REF:0000052, GO:0048589=GO_REF:0000019, GO:0040015=GO_REF:0000019, GO:0000086=Reactome:REACT_2203, GO:0016197=PMID:22693585, GO:0045444=GO_REF:0000019, GO:0005932=GO_REF:0000039, GO:0042632=GO_REF:0000019, GO:0005813=PMID:15855349, GO:0005814=PMID:20844083, GO:0046548=GO_REF:0000019, GO:0006915=GO_REF:0000019, GO:0042593=GO_REF:0000019, GO:0050673=GO_REF:0000019, GO:0008150=GO_REF:0000015, GO:0005929=GO_REF:0000037, GO:0042384=GO_REF:0000019, GO:0000922=GO_REF:0000039, GO:0006641=GO_REF:0000019, GO:0000278=Reactome:REACT_152, GO:0030728=GO_REF:0000019} Q8TCU4 Alstrom syndrome protein 1 protein 20111111 {GO:0001736=IEA, GO:0019722=IEA, GO:0060122=IEA, GO:0045598=IEA, GO:0007605=IEA, GO:0051492=IMP, GO:0007286=IEA, GO:0005829=TAS, GO:0003674=ND, GO:0005737=IDA, GO:0048589=IEA, GO:0040015=IEA, GO:0000086=TAS, GO:0016197=IMP, GO:0045444=IEA, GO:0005932=IEA, GO:0042632=IEA, GO:0005813=IDA, GO:0005814=IDA, GO:0046548=IEA, GO:0006915=IEA, GO:0042593=IEA, GO:0050673=IEA, GO:0008150=ND, GO:0005929=IEA, GO:0042384=IEA, GO:0000922=IEA, GO:0006641=IEA, GO:0000278=TAS, GO:0030728=IEA} G2/M transition of mitotic cell cycle, apoptotic process, biological_process, calcium-mediated signaling, cholesterol homeostasis, cilium assembly, developmental growth, endosomal transport, epithelial cell proliferation, establishment of planar polarity, fat cell differentiation, glucose homeostasis, inner ear receptor stereocilium organization, mitotic cell cycle, negative regulation of multicellular organism growth, ovulation, regulation of fat cell differentiation, regulation of stress fiber assembly, retinal rod cell development, sensory perception of sound, spermatid development, triglyceride metabolic process centriole, centrosome, cilium, cytoplasm, cytosol, microtubule basal body, spindle pole molecular_function Human ALOX12 Reactome UniProtKB {GO:0019369=Reactome:REACT_147851, GO:0008284=GO_REF:0000024, GO:0030307=PMID:14767568, GO:0006928=PMID:14669797, GO:0044281=Reactome:REACT_111217, GO:0006691=GO_REF:0000002, GO:0005829=Reactome:REACT_150433, GO:0071396=GO_REF:0000019, GO:0051901=GO_REF:0000019, GO:0045909=GO_REF:0000019, GO:2001300=Reactome:REACT_150320, GO:0042554=PMID:15107407, GO:0019370=GO_REF:0000037, GO:0043066=GO_REF:0000024, GO:0019395=PMID:15111312, GO:0043065=GO_REF:0000019, GO:0005506=GO_REF:0000002, GO:0019372=Reactome:REACT_150201, GO:0007568=GO_REF:0000019, GO:0072593=PMID:12858336, GO:0048661=GO_REF:0000019, GO:0045785=PMID:14669797, GO:0043280=GO_REF:0000019, GO:0010628=GO_REF:0000019, GO:0010595=GO_REF:0000019, GO:0042383=PMID:15107407, GO:0004052=Reactome:REACT_150327, GO:0016165=GO_REF:0000002, GO:0047977=GO_REF:0000024, GO:0016702=Reactome:REACT_150303, GO:0051121=Reactome:REACT_150292, GO:0045603=GO_REF:0000019, GO:0051120=Reactome:REACT_150129} P18054 Arachidonate 12-lipoxygenase, 12S-type protein 20120224 {GO:0019369=TAS, GO:0008284=ISS, GO:0030307=IMP, GO:0006928=IMP, GO:0044281=TAS, GO:0006691=IEA, GO:0005829=TAS, GO:0071396=IEA, GO:0051901=IEA, GO:0045909=IEA, GO:2001300=TAS, GO:0042554=NAS, GO:0019370=IEA, GO:0043066=ISS, GO:0019395=IMP, GO:0043065=IEA, GO:0005506=IEA, GO:0019372=TAS, GO:0007568=IEA, GO:0072593=NAS, GO:0048661=IEA, GO:0045785=IMP, GO:0043280=IEA, GO:0010628=IEA, GO:0010595=IEA, GO:0042383=IDA, GO:0004052=TAS, GO:0016165=IEA, GO:0047977=ISS, GO:0016702=TAS, GO:0051121=TAS, GO:0045603=IEA, GO:0051120=TAS} aging, arachidonic acid metabolic process, cellular component movement, cellular response to lipid, fatty acid oxidation, hepoxilin metabolic process, leukotriene biosynthetic process, leukotriene metabolic process, lipoxin metabolic process, lipoxygenase pathway, negative regulation of apoptotic process, positive regulation of apoptotic process, positive regulation of cell adhesion, positive regulation of cell growth, positive regulation of cell proliferation, positive regulation of cysteine-type endopeptidase activity involved in apoptotic process, positive regulation of endothelial cell differentiation, positive regulation of endothelial cell migration, positive regulation of gene expression, positive regulation of mitochondrial depolarization, positive regulation of smooth muscle cell proliferation, positive regulation of vasodilation, reactive oxygen species metabolic process, small molecule metabolic process, superoxide anion generation cytosol, sarcolemma arachidonate 12-lipoxygenase activity, hepoxilin A3 synthase activity, hepoxilin-epoxide hydrolase activity, iron ion binding, lipoxygenase activity, oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen Human ALOX12B Reactome UniProtKB {GO:0019369=Reactome:REACT_147851, GO:0006629=PMID:9618483, GO:0019370=GO_REF:0000037, GO:0004052=Reactome:REACT_150226, GO:0008544=PMID:9618483, GO:0005506=GO_REF:0000002, GO:0016165=GO_REF:0000002, GO:0019372=Reactome:REACT_150201, GO:0044281=Reactome:REACT_111217, GO:0005829=Reactome:REACT_150226} O75342 Arachidonate 12-lipoxygenase, 12R-type protein 20120224 {GO:0019369=TAS, GO:0006629=TAS, GO:0019370=IEA, GO:0004052=TAS, GO:0008544=TAS, GO:0005506=IEA, GO:0016165=IEA, GO:0019372=TAS, GO:0044281=TAS, GO:0005829=TAS} arachidonic acid metabolic process, epidermis development, leukotriene biosynthetic process, lipid metabolic process, lipoxygenase pathway, small molecule metabolic process cytosol arachidonate 12-lipoxygenase activity, iron ion binding, lipoxygenase activity Human ALOX15B Reactome UniProtKB {GO:0019369=Reactome:REACT_147851, GO:0006629=PMID:11839751, GO:0019370=GO_REF:0000037, GO:0030336=PMID:11839751, GO:0008285=PMID:11839751, GO:0005506=GO_REF:0000002, GO:0019372=Reactome:REACT_150422, GO:0044281=Reactome:REACT_111217, GO:0006917=PMID:11839751, GO:0045786=PMID:11839751, GO:0006691=GO_REF:0000002, GO:0005829=Reactome:REACT_150130, GO:0005622=PMID:11839751, GO:0030856=PMID:11839751, GO:0016165=GO_REF:0000002, GO:0006631=PMID:9177185, GO:0030850=PMID:11839751, GO:0045926=PMID:11839751, GO:0050473=PMID:11839751} O15296 Arachidonate 15-lipoxygenase B protein 20120224 {GO:0019369=TAS, GO:0006629=TAS, GO:0019370=IEA, GO:0030336=TAS, GO:0008285=IDA, GO:0005506=IEA, GO:0019372=TAS, GO:0044281=TAS, GO:0006917=TAS, GO:0045786=IDA, GO:0006691=IEA, GO:0005829=TAS, GO:0005622=IDA, GO:0030856=NAS, GO:0016165=IEA, GO:0006631=TAS, GO:0030850=NAS, GO:0045926=IDA, GO:0050473=IDA} arachidonic acid metabolic process, fatty acid metabolic process, induction of apoptosis, leukotriene biosynthetic process, leukotriene metabolic process, lipid metabolic process, lipoxygenase pathway, negative regulation of cell cycle, negative regulation of cell migration, negative regulation of cell proliferation, negative regulation of growth, prostate gland development, regulation of epithelial cell differentiation, small molecule metabolic process cytosol, intracellular arachidonate 15-lipoxygenase activity, iron ion binding, lipoxygenase activity Human ALOX5 IntAct UniProtKB {GO:0005515=PMID:11297527, GO:0019369=Reactome:REACT_147851, GO:0019370=PMID:21233389, GO:0031965=PMID:8245774, GO:0005506=PMID:21233389, GO:0019372=Reactome:REACT_150209, GO:0044281=Reactome:REACT_111217, GO:0005635=Reactome:REACT_150273, GO:0006691=Reactome:REACT_150420, GO:0016363=PMID:19233132, GO:0005829=Reactome:REACT_22105, GO:0004051=PMID:21233389, GO:0002540=GO_REF:0000019, GO:0016165=GO_REF:0000002, GO:0005641=PMID:8245774, GO:2001300=Reactome:REACT_150320} P09917 Arachidonate 5-lipoxygenase protein 20130415 {GO:0005515=IPI, GO:0019369=TAS, GO:0019370=IDA, GO:0031965=IDA, GO:0005506=IDA, GO:0019372=TAS, GO:0044281=TAS, GO:0005635=TAS, GO:0006691=TAS, GO:0016363=IDA, GO:0005829=TAS, GO:0004051=IDA, GO:0002540=IEA, GO:0016165=IEA, GO:0005641=IDA, GO:2001300=TAS} arachidonic acid metabolic process, leukotriene biosynthetic process, leukotriene metabolic process, leukotriene production involved in inflammatory response, lipoxin metabolic process, lipoxygenase pathway, small molecule metabolic process cytosol, nuclear envelope, nuclear envelope lumen, nuclear matrix, nuclear membrane arachidonate 5-lipoxygenase activity, iron ion binding, lipoxygenase activity, protein binding Human UniProtKB:Q14019 ALOX5AP Reactome UniProtKB {GO:0005515=PMID:19233132, GO:0019369=Reactome:REACT_147851, GO:0050544=PMID:8440384, GO:0005783=PMID:19233132, GO:0044281=Reactome:REACT_111217, GO:0005635=Reactome:REACT_150273, GO:0006691=Reactome:REACT_150420, GO:0042803=GO_REF:0000019, GO:0005829=GO_REF:0000019, GO:0004602=GO_REF:0000033, GO:0070207=PMID:17600184, GO:0002675=GO_REF:0000019, GO:0002540=GO_REF:0000019, GO:0006750=GO_REF:0000033, GO:0071277=PMID:2300173, GO:2001300=Reactome:REACT_150320, GO:0019370=PMID:2300173, GO:0031965=PMID:8245774, GO:0046982=GO_REF:0000019, GO:0019372=Reactome:REACT_150209, GO:0004464=GO_REF:0000033, GO:0004364=GO_REF:0000033, GO:0004051=GO_REF:0000033, GO:0047485=PMID:19233132, GO:0005789=GO_REF:0000039, GO:0016021=GO_REF:0000037, GO:0019899=GO_REF:0000019, GO:0008047=GO_REF:0000002} P20292 Arachidonate 5-lipoxygenase-activating protein protein 20130213 {GO:0005515=IPI, GO:0019369=TAS, GO:0050544=IDA, GO:0005783=IDA, GO:0044281=TAS, GO:0005635=TAS, GO:0006691=TAS, GO:0042803=IEA, GO:0005829=IEA, GO:0004602=IBA, GO:0070207=IPI, GO:0002675=IEA, GO:0002540=IEA, GO:0006750=IBA, GO:0071277=IDA, GO:2001300=TAS, GO:0019370=IDA, GO:0031965=IDA, GO:0046982=IEA, GO:0019372=TAS, GO:0004464=IBA, GO:0004364=IBA, GO:0004051=IBA, GO:0047485=IPI, GO:0005789=IEA, GO:0016021=IEA, GO:0019899=IEA, GO:0008047=IEA} arachidonic acid metabolic process, cellular response to calcium ion, glutathione biosynthetic process, leukotriene biosynthetic process, leukotriene metabolic process, leukotriene production involved in inflammatory response, lipoxin metabolic process, lipoxygenase pathway, positive regulation of acute inflammatory response, protein homotrimerization, small molecule metabolic process cytosol, endoplasmic reticulum, endoplasmic reticulum membrane, integral to membrane, nuclear envelope, nuclear membrane arachidonate 5-lipoxygenase activity, arachidonic acid binding, enzyme activator activity, enzyme binding, glutathione peroxidase activity, glutathione transferase activity, leukotriene-C4 synthase activity, protein N-terminus binding, protein binding, protein heterodimerization activity, protein homodimerization activity Human ALOXE3 UniProtKB UniProtKB {GO:0019370=GO_REF:0000037, GO:0005506=GO_REF:0000002, GO:0016165=GO_REF:0000002, GO:0016702=GO_REF:0000038, GO:0046872=GO_REF:0000038} Q9BYJ1 Epidermis-type lipoxygenase 3 protein 20130413 {GO:0019370=IEA, GO:0005506=IEA, GO:0016165=IEA, GO:0016702=IEA, GO:0046872=IEA} leukotriene biosynthetic process iron ion binding, lipoxygenase activity, metal ion binding, oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen Human UniProtKB-KW:KW-0434 ALPI UniProtKB UniProtKB {GO:0016310=GO_REF:0000029, GO:0016020=GO_REF:0000029, GO:0004035=PMID:2841341, GO:0005886=GO_REF:0000039, GO:0031225=GO_REF:0000037, GO:0016021=GO_REF:0000037, GO:0046872=GO_REF:0000037} P09923 Intestinal-type alkaline phosphatase protein 20021104 {GO:0016310=NAS, GO:0016020=NAS, GO:0004035=NAS, GO:0005886=IEA, GO:0031225=IEA, GO:0016021=IEA, GO:0046872=IEA} phosphorylation anchored to membrane, integral to membrane, membrane, plasma membrane alkaline phosphatase activity, metal ion binding Human ALPK1 UniProtKB UniProtKB {GO:0004674=GO_REF:0000037, GO:0016301=GO_REF:0000038, GO:0005524=GO_REF:0000002} Q96QP1 Alpha-protein kinase 1 protein 20130413 {GO:0004674=IEA, GO:0016301=IEA, GO:0005524=IEA} ATP binding, kinase activity, protein serine/threonine kinase activity Human UniProtKB-KW:KW-0723 ALPK2 UniProtKB UniProtKB {GO:0004674=GO_REF:0000037, GO:0005524=GO_REF:0000002} Q86TB3 Alpha-protein kinase 2 protein 20130413 {GO:0004674=IEA, GO:0005524=IEA} ATP binding, protein serine/threonine kinase activity Human UniProtKB-KW:KW-0723 ALPL BHF-UCL UniProtKB {GO:0005886=GO_REF:0000039, GO:0071529=GO_REF:0000019, GO:0033280=PMID:17023519, GO:0051384=GO_REF:0000019, GO:0031225=GO_REF:0000037, GO:0005615=GO_REF:0000019, GO:0046872=GO_REF:0000037, GO:0003006=GO_REF:0000019, GO:0001501=PMID:9781036, GO:0001958=GO_REF:0000019, GO:0016462=PMID:19874193, GO:0071407=GO_REF:0000019, GO:0004035=GO_REF:0000003, GO:0032496=GO_REF:0000019, GO:0016021=GO_REF:0000037, GO:0044420=GO_REF:0000019, GO:0046677=GO_REF:0000019} P05186 Alkaline phosphatase, tissue-nonspecific isozyme protein 20090507 {GO:0005886=IEA, GO:0071529=IEA, GO:0033280=IEP, GO:0051384=IEA, GO:0031225=IEA, GO:0005615=IEA, GO:0046872=IEA, GO:0003006=IEA, GO:0001501=TAS, GO:0001958=IEA, GO:0016462=IDA, GO:0071407=IEA, GO:0004035=IEA, GO:0032496=IEA, GO:0016021=IEA, GO:0044420=IEA, GO:0046677=IEA} cellular response to organic cyclic compound, cementum mineralization, developmental process involved in reproduction, endochondral ossification, response to antibiotic, response to glucocorticoid stimulus, response to lipopolysaccharide, response to vitamin D, skeletal system development anchored to membrane, extracellular matrix part, extracellular space, integral to membrane, plasma membrane alkaline phosphatase activity, metal ion binding, pyrophosphatase activity Human ALPP MGI UniProtKB {GO:0004035=PMID:2133555, GO:0009986=PMID:12493773, GO:0005886=GO_REF:0000039, GO:0031225=GO_REF:0000037, GO:0016021=GO_REF:0000037, GO:0046872=GO_REF:0000037} P05187 Alkaline phosphatase, placental type protein 20100113 {GO:0004035=IDA, GO:0009986=IDA, GO:0005886=IEA, GO:0031225=IEA, GO:0016021=IEA, GO:0046872=IEA} anchored to membrane, cell surface, integral to membrane, plasma membrane alkaline phosphatase activity, metal ion binding Human ALPPL2 UniProtKB UniProtKB {GO:0016310=GO_REF:0000029, GO:0016020=GO_REF:0000029, GO:0004035=PMID:2162249, GO:0005886=GO_REF:0000039, GO:0031225=GO_REF:0000037, GO:0046872=GO_REF:0000037} P10696 Alkaline phosphatase, placental-like protein 20021104 {GO:0016310=NAS, GO:0016020=NAS, GO:0004035=NAS, GO:0005886=IEA, GO:0031225=IEA, GO:0046872=IEA} phosphorylation anchored to membrane, membrane, plasma membrane alkaline phosphatase activity, metal ion binding Human ALS2 GOC UniProtKB {GO:0008219=GO_REF:0000019, GO:0030424=GO_REF:0000019, GO:0071902=PMID:16049005, GO:0035022=PMID:16049005, GO:0035023=GO_REF:0000002, GO:0007409=GO_REF:0000019, GO:0032855=PMID:16049005, GO:0042803=PMID:15247254, GO:0030425=PMID:15371724, GO:0005829=PMID:12837691, GO:0043231=GO_REF:0000019, GO:0030426=GO_REF:0000024, GO:0005085=PMID:15247254, GO:0005622=GO_REF:0000002, GO:0016050=GO_REF:0000019, GO:0005737=GO_REF:0000019, GO:0032313=GO_REF:0000019, GO:0005543=GO_REF:0000002, GO:0008104=GO_REF:0000019, GO:0051036=PMID:15247254, GO:0001881=GO_REF:0000019, GO:0007528=GO_REF:0000019, GO:0045860=PMID:16049005, GO:0016197=GO_REF:0000019, GO:0043025=GO_REF:0000019, GO:0001662=GO_REF:0000019, GO:0007626=GO_REF:0000019, GO:0007032=PMID:17239822, GO:0005089=GO_REF:0000002, GO:0006979=GO_REF:0000019, GO:0030676=PMID:16049005, GO:0005087=PMID:11586298, GO:0017112=PMID:12837691, GO:0017137=PMID:16670179, GO:0005813=PMID:16085057, GO:0035249=GO_REF:0000019, GO:0014069=GO_REF:0000019, GO:0031982=PMID:12837691, GO:0001726=GO_REF:0000024, GO:0001701=GO_REF:0000019, GO:0030027=GO_REF:0000024, GO:0043234=PMID:15247254, GO:0016601=GO_REF:0000019, GO:0016020=GO_REF:0000019, GO:0048812=PMID:16049005, GO:0043539=PMID:16049005, GO:0005769=PMID:12837691} Q96Q42 Alsin protein 20130413 {GO:0008219=IEA, GO:0030424=IEA, GO:0071902=IDA, GO:0035022=IC, GO:0035023=IEA, GO:0007409=IEA, GO:0032855=IDA, GO:0042803=IPI, GO:0030425=IDA, GO:0005829=IDA, GO:0043231=IEA, GO:0030426=ISS, GO:0005085=IDA, GO:0005622=IEA, GO:0016050=IEA, GO:0005737=IEA, GO:0032313=IEA, GO:0005543=IEA, GO:0008104=IEA, GO:0051036=IEP, GO:0001881=IEA, GO:0007528=IEA, GO:0045860=IDA, GO:0016197=IEA, GO:0043025=IEA, GO:0001662=IEA, GO:0007626=IEA, GO:0007032=IGI, GO:0005089=IEA, GO:0006979=IEA, GO:0030676=IDA, GO:0005087=NAS, GO:0017112=IDA, GO:0017137=NAS, GO:0005813=IDA, GO:0035249=IEA, GO:0014069=IEA, GO:0031982=IDA, GO:0001726=ISS, GO:0001701=IEA, GO:0030027=ISS, GO:0043234=IDA, GO:0016601=IEA, GO:0016020=IEA, GO:0048812=IDA, GO:0043539=IDA, GO:0005769=IDA} Rac protein signal transduction, axonogenesis, behavioral fear response, cell death, endosomal transport, endosome organization, in utero embryonic development, locomotory behavior, neuromuscular junction development, neuron projection morphogenesis, positive regulation of Rac GTPase activity, positive regulation of Rac protein signal transduction, positive regulation of protein kinase activity, positive regulation of protein serine/threonine kinase activity, protein localization, receptor recycling, regulation of Rab GTPase activity, regulation of Rho protein signal transduction, regulation of endosome size, response to oxidative stress, synaptic transmission, glutamatergic, vesicle organization axon, centrosome, cytoplasm, cytosol, dendrite, early endosome, growth cone, intracellular, intracellular membrane-bounded organelle, lamellipodium, membrane, neuronal cell body, postsynaptic density, protein complex, ruffle, vesicle Rab GTPase binding, Rab guanyl-nucleotide exchange factor activity, Rac guanyl-nucleotide exchange factor activity, Ran guanyl-nucleotide exchange factor activity, Rho guanyl-nucleotide exchange factor activity, guanyl-nucleotide exchange factor activity, phospholipid binding, protein homodimerization activity, protein serine/threonine kinase activator activity Human ALS2CL MGI UniProtKB {GO:0005622=GO_REF:0000002, GO:0017137=GO_REF:0000019, GO:0008104=GO_REF:0000019, GO:0035023=GO_REF:0000002, GO:0016023=GO_REF:0000019, GO:0007032=PMID:17239822, GO:0005089=GO_REF:0000002, GO:0042802=PMID:17239822, GO:0005096=GO_REF:0000037} Q60I27 ALS2 C-terminal-like protein protein 20070418 {GO:0005622=IEA, GO:0017137=IEA, GO:0008104=IEA, GO:0035023=IEA, GO:0016023=IEA, GO:0007032=IGI, GO:0005089=IEA, GO:0042802=IPI, GO:0005096=IEA} endosome organization, protein localization, regulation of Rho protein signal transduction cytoplasmic membrane-bounded vesicle, intracellular GTPase activator activity, Rab GTPase binding, Rho guanyl-nucleotide exchange factor activity, identical protein binding Human UniProtKB:Q60I27 ALS2CR11 null null {} null null null null {} null null null ALS2CR12 IntAct UniProtKB {GO:0005515=PMID:19060904, GO:0003674=GO_REF:0000015, GO:0005737=GO_REF:0000019, GO:0005575=GO_REF:0000015, GO:0043087=PMID:11586298} Q96Q35 Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 12 protein protein 20130415 {GO:0005515=IPI, GO:0003674=ND, GO:0005737=IEA, GO:0005575=ND, GO:0043087=NAS} regulation of GTPase activity cellular_component, cytoplasm molecular_function, protein binding Human UniProtKB:O00204 ALS2CR8 ENSEMBL UniProtKB {GO:0003700=GO_REF:0000019, GO:0005730=GO_REF:0000019, GO:0005654=GO_REF:0000019} Q8N187 Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 8 protein protein 20130413 {GO:0003700=IEA, GO:0005730=IEA, GO:0005654=IEA} nucleolus, nucleoplasm sequence-specific DNA binding transcription factor activity Human Ensembl:ENSMUSP00000027171 ALX1 IntAct UniProtKB {GO:0005515=PMID:16189514, GO:0005667=GO_REF:0000019, GO:0003700=GO_REF:0000019, GO:0006366=PMID:8756334, GO:0046982=GO_REF:0000019, GO:0003714=PMID:8756334, GO:0001843=GO_REF:0000019, GO:0007275=PMID:8756334, GO:0048704=GO_REF:0000019, GO:0005634=PMID:9753625, GO:0000122=PMID:8756334, GO:0030326=GO_REF:0000019, GO:0009952=GO_REF:0000019, GO:0043565=GO_REF:0000019, GO:0007420=PMID:8673125, GO:0001502=PMID:8756334, GO:0045944=GO_REF:0000019, GO:0014031=GO_REF:0000019, GO:0060021=GO_REF:0000019, GO:0045893=PMID:9753625} Q15699 ALX homeobox protein 1 protein 20130415 {GO:0005515=IPI, GO:0005667=IEA, GO:0003700=IEA, GO:0006366=TAS, GO:0046982=IEA, GO:0003714=TAS, GO:0001843=IEA, GO:0007275=TAS, GO:0048704=IEA, GO:0005634=IDA, GO:0000122=IDA, GO:0030326=IEA, GO:0009952=IEA, GO:0043565=IEA, GO:0007420=TAS, GO:0001502=TAS, GO:0045944=IEA, GO:0014031=IEA, GO:0060021=IEA, GO:0045893=IDA} anterior/posterior pattern specification, brain development, cartilage condensation, embryonic limb morphogenesis, embryonic skeletal system morphogenesis, mesenchymal cell development, multicellular organismal development, negative regulation of transcription from RNA polymerase II promoter, neural tube closure, palate development, positive regulation of transcription from RNA polymerase II promoter, positive regulation of transcription, DNA-dependent, transcription from RNA polymerase II promoter nucleus, transcription factor complex protein binding, protein heterodimerization activity, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, transcription corepressor activity Human UniProtKB:O94829 ALX4 UniProtKB UniProtKB {GO:0005667=GO_REF:0000019, GO:0003700=GO_REF:0000019, GO:0046982=GO_REF:0000019, GO:0005634=PMID:19692347, GO:0048704=GO_REF:0000019, GO:0048565=GO_REF:0000019, GO:0042981=GO_REF:0000019, GO:0009791=GO_REF:0000019, GO:0009952=GO_REF:0000019, GO:0003677=PMID:11137991, GO:0006351=GO_REF:0000037, GO:0043565=GO_REF:0000019, GO:0001501=PMID:11106354, GO:0007517=GO_REF:0000019, GO:0045944=GO_REF:0000019, GO:0035116=GO_REF:0000019, GO:0071837=GO_REF:0000019, GO:0060021=GO_REF:0000019, GO:0035115=GO_REF:0000019, GO:0001942=PMID:19692347, GO:0042733=GO_REF:0000019} Q9H161 Homeobox protein aristaless-like 4 protein 20100901 {GO:0005667=IEA, GO:0003700=IEA, GO:0046982=IEA, GO:0005634=IDA, GO:0048704=IEA, GO:0048565=IEA, GO:0042981=IEA, GO:0009791=IEA, GO:0009952=IEA, GO:0003677=NAS, GO:0006351=IEA, GO:0043565=IEA, GO:0001501=NAS, GO:0007517=IEA, GO:0045944=IEA, GO:0035116=IEA, GO:0071837=IEA, GO:0060021=IEA, GO:0035115=IEA, GO:0001942=IMP, GO:0042733=IEA} anterior/posterior pattern specification, digestive tract development, embryonic digit morphogenesis, embryonic forelimb morphogenesis, embryonic hindlimb morphogenesis, embryonic skeletal system morphogenesis, hair follicle development, muscle organ development, palate development, positive regulation of transcription from RNA polymerase II promoter, post-embryonic development, regulation of apoptotic process, skeletal system development, transcription, DNA-dependent nucleus, transcription factor complex DNA binding, HMG box domain binding, protein heterodimerization activity, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity Human AMACR Reactome UniProtKB {GO:0005739=PMID:7649182, GO:0005782=Reactome:REACT_17018, GO:0006699=Reactome:REACT_11054, GO:0005102=PMID:20178365, GO:0008206=Reactome:REACT_11040, GO:0044281=Reactome:REACT_111217, GO:0033540=Reactome:REACT_17017, GO:0003824=GO_REF:0000002, GO:0044255=Reactome:REACT_16957, GO:0005777=PMID:7649182} Q9UHK6 Alpha-methylacyl-CoA racemase protein 20130301 {GO:0005739=IDA, GO:0005782=TAS, GO:0006699=TAS, GO:0005102=IPI, GO:0008206=TAS, GO:0044281=TAS, GO:0033540=TAS, GO:0003824=IEA, GO:0044255=TAS, GO:0005777=IDA} bile acid biosynthetic process, bile acid metabolic process, cellular lipid metabolic process, fatty acid beta-oxidation using acyl-CoA oxidase, small molecule metabolic process mitochondrion, peroxisomal matrix, peroxisome catalytic activity, receptor binding Human AMBN BHF-UCL UniProtKB {GO:0030345=GO_REF:0000029, GO:0008283=GO_REF:0000024, GO:0005578=GO_REF:0000029, GO:0042475=GO_REF:0000002, GO:0030282=GO_REF:0000029, GO:0007155=GO_REF:0000024, GO:0008083=GO_REF:0000024} Q9NP70 Ameloblastin protein 20081126 {GO:0030345=NAS, GO:0008283=ISS, GO:0005578=NAS, GO:0042475=IEA, GO:0030282=NAS, GO:0007155=ISS, GO:0008083=ISS} bone mineralization, cell adhesion, cell proliferation, odontogenesis of dentin-containing tooth proteinaceous extracellular matrix growth factor activity, structural constituent of tooth enamel Human UniProtKB:O55189 AMBP Reactome UniProtKB {GO:0007565=PMID:10097787, GO:0009986=GO_REF:0000019, GO:0005886=PMID:12817471, GO:0004867=PMID:12817471, GO:0036094=GO_REF:0000002, GO:0005576=Reactome:REACT_160303, GO:0005615=GO_REF:0000019, GO:0042803=PMID:11883904, GO:0046904=PMID:14516400, GO:0043231=GO_REF:0000019, GO:0018298=GO_REF:0000037, GO:0030163=GO_REF:0000019, GO:0046329=PMID:12817471, GO:0019862=PMID:11877257, GO:0050777=PMID:10097787, GO:0019855=PMID:12817471, GO:0019048=GO_REF:0000037, GO:0042167=PMID:11877257, GO:0007155=PMID:9570066, GO:0020037=PMID:11877257} P02760 Protein AMBP protein 20120423 {GO:0007565=NAS, GO:0009986=IEA, GO:0005886=IDA, GO:0004867=TAS, GO:0036094=IEA, GO:0005576=TAS, GO:0005615=IEA, GO:0042803=IPI, GO:0046904=NAS, GO:0043231=IEA, GO:0018298=IEA, GO:0030163=IEA, GO:0046329=TAS, GO:0019862=IDA, GO:0050777=NAS, GO:0019855=NAS, GO:0019048=IEA, GO:0042167=NAS, GO:0007155=NAS, GO:0020037=IDA} cell adhesion, female pregnancy, heme catabolic process, negative regulation of JNK cascade, negative regulation of immune response, protein catabolic process, protein-chromophore linkage, virus-host interaction cell surface, extracellular region, extracellular space, intracellular membrane-bounded organelle, plasma membrane IgA binding, calcium channel inhibitor activity, calcium oxalate binding, heme binding, protein homodimerization activity, serine-type endopeptidase inhibitor activity, small molecule binding Human AMBRA1 IntAct UniProtKB {GO:0005515=PMID:22190034, GO:0005737=PMID:17589504, GO:0005776=GO_REF:0000039, GO:0043065=GO_REF:0000019, GO:0008285=GO_REF:0000019, GO:0021915=GO_REF:0000019, GO:0006914=GO_REF:0000019, GO:0031410=GO_REF:0000037, GO:0030154=GO_REF:0000037} Q9C0C7 Activating molecule in BECN1-regulated autophagy protein 1 protein 20130415 {GO:0005515=IPI, GO:0005737=IDA, GO:0005776=IEA, GO:0043065=IEA, GO:0008285=IEA, GO:0021915=IEA, GO:0006914=IEA, GO:0031410=IEA, GO:0030154=IEA} autophagy, cell differentiation, negative regulation of cell proliferation, neural tube development, positive regulation of apoptotic process autophagic vacuole, cytoplasm, cytoplasmic vesicle protein binding Human UniProtKB:P12504 AMD1 InterPro UniProtKB {GO:0008295=GO_REF:0000002, GO:0034641=Reactome:REACT_13, GO:0004014=GO_REF:0000002, GO:0006597=GO_REF:0000002, GO:0006595=Reactome:REACT_14820, GO:0006557=GO_REF:0000041, GO:0044281=Reactome:REACT_111217, GO:0005829=Reactome:REACT_14840} Q5VXN5 cDNA, FLJ79370, highly similar to S-adenosylmethionine decarboxylase proenzyme (EC 4.1.1.50) protein 20130413 {GO:0008295=IEA, GO:0034641=TAS, GO:0004014=IEA, GO:0006597=IEA, GO:0006595=TAS, GO:0006557=IEA, GO:0044281=TAS, GO:0005829=TAS} S-adenosylmethioninamine biosynthetic process, cellular nitrogen compound metabolic process, polyamine metabolic process, small molecule metabolic process, spermidine biosynthetic process, spermine biosynthetic process cytosol adenosylmethionine decarboxylase activity Human InterPro:IPR001985|InterPro:IPR016067 AMDHD1 BHF-UCL UniProtKB {GO:0003674=GO_REF:0000015, GO:0034641=Reactome:REACT_13, GO:0050480=GO_REF:0000003, GO:0019557=GO_REF:0000041, GO:0019556=GO_REF:0000041, GO:0006548=Reactome:REACT_1249, GO:0044281=Reactome:REACT_111217, GO:0046872=GO_REF:0000037, GO:0005829=Reactome:REACT_573} Q96NU7 Probable imidazolonepropionase protein 20120523 {GO:0003674=ND, GO:0034641=TAS, GO:0050480=IEA, GO:0019557=IEA, GO:0019556=IEA, GO:0006548=TAS, GO:0044281=TAS, GO:0046872=IEA, GO:0005829=TAS} cellular nitrogen compound metabolic process, histidine catabolic process, histidine catabolic process to glutamate and formamide, histidine catabolic process to glutamate and formate, small molecule metabolic process cytosol imidazolonepropionase activity, metal ion binding, molecular_function Human AMDHD2 UniProtKB UniProtKB {GO:0016787=GO_REF:0000002, GO:0016810=GO_REF:0000002, GO:0005975=GO_REF:0000037, GO:0006044=GO_REF:0000002, GO:0008448=PMID:22692205, GO:0019262=PMID:22692205, GO:0046872=GO_REF:0000037} Q9Y303 Putative N-acetylglucosamine-6-phosphate deacetylase protein 20121102 {GO:0016787=IEA, GO:0016810=IEA, GO:0005975=IEA, GO:0006044=IEA, GO:0008448=IDA, GO:0019262=TAS, GO:0046872=IEA} N-acetylglucosamine metabolic process, N-acetylneuraminate catabolic process, carbohydrate metabolic process N-acetylglucosamine-6-phosphate deacetylase activity, hydrolase activity, hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, metal ion binding Human AMELX BHF-UCL UniProtKB {GO:0005515=PMID:18434575, GO:0030345=PMID:2509010, GO:0043498=PMID:1734713, GO:0034505=PMID:1483698, GO:0008283=PMID:1734713, GO:0070172=PMID:2509010, GO:0070166=PMID:1916828, GO:0005578=PMID:2509010, GO:0050801=PMID:2509010, GO:0001837=PMID:1734713, GO:0031214=PMID:2509010, GO:0001649=PMID:1734713, GO:0042802=PMID:1734713, GO:0007165=PMID:16674683, GO:0032967=PMID:1734713, GO:0046848=PMID:1734713, GO:0002062=PMID:1734713, GO:0042475=PMID:1734713, GO:0007155=PMID:1734713, GO:0008083=PMID:1734713} Q99217 Amelogenin, X isoform protein 20081126 {GO:0005515=IPI, GO:0030345=IDA, GO:0043498=ISS, GO:0034505=IMP, GO:0008283=ISS, GO:0070172=TAS, GO:0070166=IMP, GO:0005578=IDA, GO:0050801=TAS, GO:0001837=ISS, GO:0031214=TAS, GO:0001649=ISS, GO:0042802=ISS, GO:0007165=TAS, GO:0032967=ISS, GO:0046848=ISS, GO:0002062=ISS, GO:0042475=ISS, GO:0007155=ISS, GO:0008083=ISS} biomineral tissue development, cell adhesion, cell proliferation, chondrocyte differentiation, enamel mineralization, epithelial to mesenchymal transition, ion homeostasis, odontogenesis of dentin-containing tooth, osteoblast differentiation, positive regulation of collagen biosynthetic process, positive regulation of tooth mineralization, signal transduction, tooth mineralization proteinaceous extracellular matrix cell surface binding, growth factor activity, hydroxyapatite binding, identical protein binding, protein binding, structural constituent of tooth enamel Human AMFR PINC UniProtKB {GO:0005515=PMID:17681147, GO:0000209=PMID:19103148, GO:0006511=PMID:17043353, GO:0004842=PMID:19103148, GO:0006928=PMID:1649192, GO:0030176=PMID:11724934, GO:0030433=PMID:16168377, GO:0051259=PMID:17310145, GO:0030968=PMID:17157811, GO:0007165=PMID:1649192, GO:0008270=GO_REF:0000002, GO:0004872=PMID:1649192, GO:0016021=PMID:1649192} Q9UKV5 E3 ubiquitin-protein ligase AMFR protein 20030904 {GO:0005515=IPI, GO:0000209=IDA, GO:0006511=IMP, GO:0004842=IDA, GO:0006928=TAS, GO:0030176=IDA, GO:0030433=IMP, GO:0051259=IDA, GO:0030968=IMP, GO:0007165=TAS, GO:0008270=IEA, GO:0004872=IPI, GO:0016021=NAS} ER-associated protein catabolic process, cellular component movement, endoplasmic reticulum unfolded protein response, protein oligomerization, protein polyubiquitination, signal transduction, ubiquitin-dependent protein catabolic process integral to endoplasmic reticulum membrane, integral to membrane protein binding, receptor activity, ubiquitin-protein ligase activity, zinc ion binding Human AMH PINC UniProtKB {GO:0008406=GO_REF:0000002, GO:0014070=GO_REF:0000019, GO:0042493=GO_REF:0000019, GO:0001655=GO_REF:0000019, GO:0007568=GO_REF:0000019, GO:0007267=PMID:3754790, GO:0005102=PMID:14750901, GO:0005576=PMID:14750901, GO:0005160=GO_REF:0000019, GO:0005615=GO_REF:0000019, GO:0030154=GO_REF:0000037, GO:0001546=GO_REF:0000019, GO:0007530=PMID:3754790, GO:0010628=PMID:14695376, GO:0007506=GO_REF:0000037, GO:0005737=GO_REF:0000019, GO:0051092=GO_REF:0000019, GO:0005179=PMID:3754790, GO:0001880=PMID:14695376, GO:0007548=PMID:12834017, GO:0008083=GO_REF:0000037} P03971 Muellerian-inhibiting factor protein 20030904 {GO:0008406=IEA, GO:0014070=IEA, GO:0042493=IEA, GO:0001655=IEA, GO:0007568=IEA, GO:0007267=TAS, GO:0005102=IPI, GO:0005576=NAS, GO:0005160=IEA, GO:0005615=IEA, GO:0030154=IEA, GO:0001546=IEA, GO:0007530=TAS, GO:0010628=IMP, GO:0007506=IEA, GO:0005737=IEA, GO:0051092=IEA, GO:0005179=TAS, GO:0001880=IDA, GO:0007548=TAS, GO:0008083=IEA} Mullerian duct regression, aging, cell differentiation, cell-cell signaling, gonad development, gonadal mesoderm development, positive regulation of NF-kappaB transcription factor activity, positive regulation of gene expression, preantral ovarian follicle growth, response to drug, response to organic cyclic compound, sex determination, sex differentiation, urogenital system development cytoplasm, extracellular region, extracellular space growth factor activity, hormone activity, receptor binding, transforming growth factor beta receptor binding Human AMHR2 IntAct UniProtKB {GO:0005515=PMID:22939624, GO:0007165=PMID:7493017, GO:0005887=GO_REF:0000019, GO:0042562=PMID:14750901, GO:0001880=PMID:14750901, GO:0004872=PMID:7493017, GO:0007548=PMID:12834017, GO:0007179=GO_REF:0000019, GO:0005524=GO_REF:0000037, GO:0046872=GO_REF:0000037, GO:0005026=GO_REF:0000019} Q16671 Anti-Muellerian hormone type-2 receptor protein 20130415 {GO:0005515=IPI, GO:0007165=IMP, GO:0005887=IEA, GO:0042562=IPI, GO:0001880=NAS, GO:0004872=IMP, GO:0007548=TAS, GO:0007179=IEA, GO:0005524=IEA, GO:0046872=IEA, GO:0005026=IEA} Mullerian duct regression, sex differentiation, signal transduction, transforming growth factor beta receptor signaling pathway integral to plasma membrane ATP binding, hormone binding, metal ion binding, protein binding, receptor activity, transforming growth factor beta receptor activity, type II Human UniProtKB:P08238 AMICA1 Reactome UniProtKB {GO:0005886=Reactome:REACT_12064, GO:0007596=Reactome:REACT_604, GO:0050776=Reactome:REACT_11152, GO:0030593=PMID:15800062, GO:0005923=PMID:15800062, GO:0016021=GO_REF:0000037, GO:0050900=Reactome:REACT_12051, GO:0050839=PMID:15800062, GO:0070633=PMID:15800062, GO:0007157=PMID:15800062} Q86YT9 Junctional adhesion molecule-like protein 20110826 {GO:0005886=TAS, GO:0007596=TAS, GO:0050776=TAS, GO:0030593=IMP, GO:0005923=IDA, GO:0016021=IEA, GO:0050900=TAS, GO:0050839=IPI, GO:0070633=IMP, GO:0007157=IDA} blood coagulation, heterophilic cell-cell adhesion, leukocyte migration, neutrophil chemotaxis, regulation of immune response, transepithelial transport integral to membrane, plasma membrane, tight junction cell adhesion molecule binding Human AMIGO1 UniProtKB UniProtKB {GO:0030424=GO_REF:0000039, GO:0007413=PMID:12629050, GO:0005886=GO_REF:0000039, GO:0042552=PMID:12629050, GO:0050772=PMID:12629050, GO:0016021=GO_REF:0000019, GO:0007156=PMID:12629050, GO:0007157=PMID:12629050} Q86WK6 Amphoterin-induced protein 1 protein 20050517 {GO:0030424=IEA, GO:0007413=ISS, GO:0005886=IEA, GO:0042552=ISS, GO:0050772=ISS, GO:0016021=IEA, GO:0007156=ISS, GO:0007157=ISS} axonal fasciculation, heterophilic cell-cell adhesion, homophilic cell adhesion, myelination, positive regulation of axonogenesis axon, integral to membrane, plasma membrane Human UniProtKB:Q80ZD7 AMIGO2 IntAct UniProtKB {GO:0005515=PMID:21078624, GO:0043069=PMID:12843293, GO:0043066=GO_REF:0000019, GO:0005886=GO_REF:0000039, GO:0005634=GO_REF:0000039, GO:0016021=GO_REF:0000037, GO:0007156=PMID:12629050, GO:0007157=PMID:12629050} Q86SJ2 Amphoterin-induced protein 2 protein 20130415 {GO:0005515=IPI, GO:0043069=ISS, GO:0043066=IEA, GO:0005886=IEA, GO:0005634=IEA, GO:0016021=IEA, GO:0007156=ISS, GO:0007157=ISS} heterophilic cell-cell adhesion, homophilic cell adhesion, negative regulation of apoptotic process, negative regulation of programmed cell death integral to membrane, nucleus, plasma membrane protein binding Human UniProtKB:O00555 AMIGO3 UniProtKB UniProtKB {GO:0016021=GO_REF:0000037, GO:0007157=PMID:12629050} Q86WK7 Amphoterin-induced protein 3 protein 20050517 {GO:0016021=IEA, GO:0007157=ISS} heterophilic cell-cell adhesion integral to membrane Human UniProtKB:Q80ZD5 AMMECR1 UniProtKB UniProtKB {GO:0003674=GO_REF:0000015, GO:0008150=GO_REF:0000015, GO:0005575=GO_REF:0000015} Q9Y4X0 AMME syndrome candidate gene 1 protein protein 20061026 {GO:0003674=ND, GO:0008150=ND, GO:0005575=ND} biological_process cellular_component molecular_function Human AMMECR1L null null {} null null null null {} null null null AMN Reactome UniProtKB {GO:0006629=Reactome:REACT_602, GO:0007588=GO_REF:0000019, GO:0008104=GO_REF:0000019, GO:0005886=Reactome:REACT_13688, GO:0042157=Reactome:REACT_13621, GO:0045177=GO_REF:0000019, GO:0007275=GO_REF:0000037, GO:0044281=Reactome:REACT_111217, GO:0016021=GO_REF:0000037} Q9BXJ7 Protein amnionless protein 20080410 {GO:0006629=TAS, GO:0007588=IEA, GO:0008104=IEA, GO:0005886=TAS, GO:0042157=TAS, GO:0045177=IEA, GO:0007275=IEA, GO:0044281=TAS, GO:0016021=IEA} excretion, lipid metabolic process, lipoprotein metabolic process, multicellular organismal development, protein localization, small molecule metabolic process apical part of cell, integral to membrane, plasma membrane Human AMOT IntAct UniProtKB {GO:0005515=PMID:21481793, GO:0030036=PMID:16043488, GO:0005884=PMID:11257124, GO:0030139=PMID:11257124, GO:0005829=Reactome:REACT_118821, GO:0042074=GO_REF:0000019, GO:0006935=GO_REF:0000019, GO:0008180=PMID:18850735, GO:0040019=GO_REF:0000019, GO:0004872=PMID:11257124, GO:0034260=GO_REF:0000019, GO:0030334=PMID:11257124, GO:0003365=GO_REF:0000019, GO:0051056=GO_REF:0000019, GO:0031410=GO_REF:0000019, GO:0035329=Reactome:REACT_118607, GO:0001701=GO_REF:0000019, GO:0001726=PMID:11257124, GO:0030027=PMID:11257124, GO:0001702=GO_REF:0000019, GO:0043534=GO_REF:0000019, GO:0043532=PMID:11257124, GO:0016525=PMID:11257124, GO:0005923=GO_REF:0000039, GO:0034613=PMID:21205866, GO:0001570=GO_REF:0000019, GO:0009897=PMID:11257124} Q4VCS5 Angiomotin protein 20130415 {GO:0005515=IPI, GO:0030036=TAS, GO:0005884=IDA, GO:0030139=IDA, GO:0005829=TAS, GO:0042074=IEA, GO:0006935=IEA, GO:0008180=IDA, GO:0040019=IEA, GO:0004872=IDA, GO:0034260=IEA, GO:0030334=IDA, GO:0003365=IEA, GO:0051056=IEA, GO:0031410=IEA, GO:0035329=TAS, GO:0001701=IEA, GO:0001726=IDA, GO:0030027=IDA, GO:0001702=IEA, GO:0043534=IEA, GO:0043532=IDA, GO:0016525=IDA, GO:0005923=IEA, GO:0034613=IDA, GO:0001570=IEA, GO:0009897=IDA} actin cytoskeleton organization, blood vessel endothelial cell migration, cell migration involved in gastrulation, cellular protein localization, chemotaxis, establishment of cell polarity involved in ameboidal cell migration, gastrulation with mouth forming second, hippo signaling cascade, in utero embryonic development, negative regulation of GTPase activity, negative regulation of angiogenesis, positive regulation of embryonic development, regulation of cell migration, regulation of small GTPase mediated signal transduction, vasculogenesis actin filament, cytoplasmic vesicle, cytosol, endocytic vesicle, external side of plasma membrane, lamellipodium, ruffle, signalosome, tight junction angiostatin binding, protein binding, receptor activity Human UniProtKB:Q68EM7 AMOTL1 HPA UniProtKB {GO:0005515=PMID:21187284, GO:0003365=GO_REF:0000019, GO:0030054=GO_REF:0000052, GO:0035329=Reactome:REACT_118607, GO:0031410=GO_REF:0000019, GO:0030027=GO_REF:0000019, GO:0042802=PMID:16019084, GO:0005829=Reactome:REACT_118821, GO:0043536=GO_REF:0000019, GO:0005737=GO_REF:0000052, GO:0016324=GO_REF:0000019, GO:0008180=PMID:18850735, GO:0005923=PMID:16019084, GO:0016055=GO_REF:0000037} Q8IY63 Angiomotin-like protein 1 protein 20080818 {GO:0005515=IPI, GO:0003365=IEA, GO:0030054=IDA, GO:0035329=TAS, GO:0031410=IEA, GO:0030027=IEA, GO:0042802=IDA, GO:0005829=TAS, GO:0043536=IEA, GO:0005737=IDA, GO:0016324=IEA, GO:0008180=IDA, GO:0005923=IDA, GO:0016055=IEA} Wnt receptor signaling pathway, establishment of cell polarity involved in ameboidal cell migration, hippo signaling cascade, positive regulation of blood vessel endothelial cell migration apical plasma membrane, cell junction, cytoplasm, cytoplasmic vesicle, cytosol, lamellipodium, signalosome, tight junction identical protein binding, protein binding Human AMOTL2 Reactome UniProtKB {GO:0005515=PMID:21187284, GO:0016324=GO_REF:0000019, GO:0035329=Reactome:REACT_118607, GO:0031410=GO_REF:0000019, GO:0005923=GO_REF:0000019, GO:0055037=GO_REF:0000039, GO:0016055=GO_REF:0000037, GO:0005829=Reactome:REACT_118821, GO:0042802=GO_REF:0000019} Q9Y2J4 Angiomotin-like protein 2 protein 20130301 {GO:0005515=IPI, GO:0016324=IEA, GO:0035329=TAS, GO:0031410=IEA, GO:0005923=IEA, GO:0055037=IEA, GO:0016055=IEA, GO:0005829=TAS, GO:0042802=IEA} Wnt receptor signaling pathway, hippo signaling cascade apical plasma membrane, cytoplasmic vesicle, cytosol, recycling endosome, tight junction identical protein binding, protein binding Human AMPD1 Reactome UniProtKB {GO:0003876=GO_REF:0000003, GO:0010033=GO_REF:0000019, GO:0006144=Reactome:REACT_522, GO:0032264=GO_REF:0000041, GO:0043101=Reactome:REACT_1923, GO:0055086=Reactome:REACT_1698, GO:0044281=Reactome:REACT_111217, GO:0046872=GO_REF:0000037, GO:0005829=Reactome:REACT_700, GO:0032036=GO_REF:0000019} P23109 AMP deaminase 1 protein 20130213 {GO:0003876=IEA, GO:0010033=IEA, GO:0006144=TAS, GO:0032264=IEA, GO:0043101=TAS, GO:0055086=TAS, GO:0044281=TAS, GO:0046872=IEA, GO:0005829=TAS, GO:0032036=IEA} IMP salvage, nucleobase-containing small molecule metabolic process, purine nucleobase metabolic process, purine-containing compound salvage, response to organic substance, small molecule metabolic process cytosol AMP deaminase activity, metal ion binding, myosin heavy chain binding Human AMPD2 Reactome UniProtKB {GO:0003876=PMID:8764830, GO:0006144=Reactome:REACT_522, GO:0032264=GO_REF:0000041, GO:0043101=Reactome:REACT_1923, GO:0055086=Reactome:REACT_1698, GO:0044281=Reactome:REACT_111217, GO:0005575=GO_REF:0000015, GO:0006188=GO_REF:0000002, GO:0006163=GO_REF:0000029, GO:0046872=GO_REF:0000037, GO:0005829=Reactome:REACT_700} Q01433 AMP deaminase 2 protein 20130213 {GO:0003876=NAS, GO:0006144=TAS, GO:0032264=IEA, GO:0043101=TAS, GO:0055086=TAS, GO:0044281=TAS, GO:0005575=ND, GO:0006188=IEA, GO:0006163=NAS, GO:0046872=IEA, GO:0005829=TAS} IMP biosynthetic process, IMP salvage, nucleobase-containing small molecule metabolic process, purine nucleobase metabolic process, purine nucleotide metabolic process, purine-containing compound salvage, small molecule metabolic process cellular_component, cytosol AMP deaminase activity, metal ion binding Human AMPD3 Reactome UniProtKB {GO:0003876=GO_REF:0000003, GO:0006196=PMID:9291127, GO:0006144=Reactome:REACT_522, GO:0032264=GO_REF:0000041, GO:0043101=Reactome:REACT_1923, GO:0055086=Reactome:REACT_1698, GO:0044281=Reactome:REACT_111217, GO:0006188=GO_REF:0000002, GO:0046872=GO_REF:0000037, GO:0005829=Reactome:REACT_700} Q01432 AMP deaminase 3 protein 20130213 {GO:0003876=IEA, GO:0006196=TAS, GO:0006144=TAS, GO:0032264=IEA, GO:0043101=TAS, GO:0055086=TAS, GO:0044281=TAS, GO:0006188=IEA, GO:0046872=IEA, GO:0005829=TAS} AMP catabolic process, IMP biosynthetic process, IMP salvage, nucleobase-containing small molecule metabolic process, purine nucleobase metabolic process, purine-containing compound salvage, small molecule metabolic process cytosol AMP deaminase activity, metal ion binding Human AMPH PINC UniProtKB {GO:0005515=PMID:20946875, GO:0005737=GO_REF:0000002, GO:0030054=GO_REF:0000037, GO:0007268=PMID:9182667, GO:0030672=GO_REF:0000039, GO:0048488=GO_REF:0000019, GO:0007612=GO_REF:0000019, GO:0015629=PMID:9182667, GO:0008021=PMID:1628617, GO:0006897=PMID:9182667} P49418 Amphiphysin protein 20030904 {GO:0005515=IPI, GO:0005737=IEA, GO:0030054=IEA, GO:0007268=TAS, GO:0030672=IEA, GO:0048488=IEA, GO:0007612=IEA, GO:0015629=TAS, GO:0008021=TAS, GO:0006897=TAS} endocytosis, learning, synaptic transmission, synaptic vesicle endocytosis actin cytoskeleton, cell junction, cytoplasm, synaptic vesicle, synaptic vesicle membrane protein binding Human AMY1A InterPro UniProtKB {GO:0005515=PMID:16203048, GO:0005975=GO_REF:0000002, GO:0007586=PMID:2423416, GO:0005576=GO_REF:0000039, GO:0003824=GO_REF:0000002, GO:0004556=GO_REF:0000003, GO:0046872=GO_REF:0000037} Q5T084 Alpha-amylase 1 protein 20130413 {GO:0005515=IPI, GO:0005975=IEA, GO:0007586=TAS, GO:0005576=IEA, GO:0003824=IEA, GO:0004556=IEA, GO:0046872=IEA} carbohydrate metabolic process, digestion extracellular region alpha-amylase activity, catalytic activity, metal ion binding, protein binding Human InterPro:IPR013781 AMY1B InterPro UniProtKB {GO:0043169=GO_REF:0000002, GO:0005975=GO_REF:0000002, GO:0003824=GO_REF:0000002} Q5T085 Alpha-amylase 1 protein 20130413 {GO:0043169=IEA, GO:0005975=IEA, GO:0003824=IEA} carbohydrate metabolic process catalytic activity, cation binding Human InterPro:IPR006046|InterPro:IPR006047 AMY1C null null {} null null null null {} null null null AMY2A Reactome UniProtKB {GO:0031404=PMID:10769135, GO:0016052=PMID:10769135, GO:0043169=GO_REF:0000002, GO:0005975=Reactome:REACT_474, GO:0005509=PMID:10769135, GO:0044245=Reactome:REACT_9472, GO:0005576=Reactome:REACT_9475, GO:0044281=Reactome:REACT_111217, GO:0003824=GO_REF:0000002, GO:0004556=PMID:10769135, GO:0005615=PMID:10769135} P04746 Pancreatic alpha-amylase protein 20130301 {GO:0031404=IDA, GO:0016052=IDA, GO:0043169=IEA, GO:0005975=TAS, GO:0005509=IDA, GO:0044245=TAS, GO:0005576=TAS, GO:0044281=TAS, GO:0003824=IEA, GO:0004556=IDA, GO:0005615=IDA} carbohydrate catabolic process, carbohydrate metabolic process, polysaccharide digestion, small molecule metabolic process extracellular region, extracellular space alpha-amylase activity, calcium ion binding, catalytic activity, cation binding, chloride ion binding Human AMZ2 UniProtKB UniProtKB {GO:0006508=GO_REF:0000037, GO:0008270=GO_REF:0000002, GO:0008237=GO_REF:0000037} Q86W34 Archaemetzincin-2 protein 20130413 {GO:0006508=IEA, GO:0008270=IEA, GO:0008237=IEA} proteolysis metallopeptidase activity, zinc ion binding Human UniProtKB-KW:KW-0482 ANAPC1 Reactome UniProtKB {GO:0007094=Reactome:REACT_2137, GO:0051437=Reactome:REACT_6904, GO:0051436=Reactome:REACT_6785, GO:0031145=Reactome:REACT_6871, GO:0051439=Reactome:REACT_6867, GO:0005829=Reactome:REACT_9035, GO:0070979=PMID:18485873, GO:0005680=PMID:16364912, GO:0000087=Reactome:REACT_910, GO:0000075=Reactome:REACT_1538, GO:0005654=Reactome:REACT_9051, GO:0000278=Reactome:REACT_152, GO:0000090=Reactome:REACT_1275, GO:0051301=GO_REF:0000037} Q9H1A4 Anaphase-promoting complex subunit 1 protein 20130301 {GO:0007094=TAS, GO:0051437=TAS, GO:0051436=TAS, GO:0031145=TAS, GO:0051439=TAS, GO:0005829=TAS, GO:0070979=IDA, GO:0005680=IDA, GO:0000087=TAS, GO:0000075=TAS, GO:0005654=TAS, GO:0000278=TAS, GO:0000090=TAS, GO:0051301=IEA} M phase of mitotic cell cycle, anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process, cell cycle checkpoint, cell division, mitotic anaphase, mitotic cell cycle, mitotic spindle assembly checkpoint, negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle, positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle, protein K11-linked ubiquitination, regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle anaphase-promoting complex, cytosol, nucleoplasm Human ANAPC10 Reactome UniProtKB {GO:0007094=Reactome:REACT_2137, GO:0006511=PMID:10318877, GO:0004842=PMID:10318877, GO:0051437=Reactome:REACT_6904, GO:0051436=Reactome:REACT_6785, GO:0031145=Reactome:REACT_6871, GO:0051439=Reactome:REACT_6867, GO:0005829=Reactome:REACT_9035, GO:0005737=GO_REF:0000019, GO:0007067=PMID:10318877, GO:0070979=PMID:18485873, GO:0005680=PMID:21926987, GO:0000086=PMID:10318877, GO:0000087=Reactome:REACT_910, GO:0000075=Reactome:REACT_1538, GO:0005654=Reactome:REACT_9051, GO:0000278=Reactome:REACT_152, GO:0000090=Reactome:REACT_1275, GO:0051301=GO_REF:0000037} Q9UM13 Anaphase-promoting complex subunit 10 protein 20130301 {GO:0007094=TAS, GO:0006511=TAS, GO:0004842=TAS, GO:0051437=TAS, GO:0051436=TAS, GO:0031145=TAS, GO:0051439=TAS, GO:0005829=TAS, GO:0005737=IEA, GO:0007067=NAS, GO:0070979=IDA, GO:0005680=IDA, GO:0000086=TAS, GO:0000087=TAS, GO:0000075=TAS, GO:0005654=TAS, GO:0000278=TAS, GO:0000090=TAS, GO:0051301=IEA} G2/M transition of mitotic cell cycle, M phase of mitotic cell cycle, anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process, cell cycle checkpoint, cell division, mitosis, mitotic anaphase, mitotic cell cycle, mitotic spindle assembly checkpoint, negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle, positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle, protein K11-linked ubiquitination, regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle, ubiquitin-dependent protein catabolic process anaphase-promoting complex, cytoplasm, cytosol, nucleoplasm ubiquitin-protein ligase activity Human ANAPC11 Reactome UniProtKB {GO:0007094=Reactome:REACT_2137, GO:0004842=PMID:11739784, GO:0016567=PMID:11739784, GO:0051437=Reactome:REACT_6904, GO:0051436=Reactome:REACT_6785, GO:0031145=Reactome:REACT_6871, GO:0051439=Reactome:REACT_6867, GO:0005829=Reactome:REACT_9035, GO:0007067=PMID:11739784, GO:0070979=PMID:18485873, GO:0005680=PMID:21926987, GO:0000087=Reactome:REACT_910, GO:0000075=Reactome:REACT_1538, GO:0008270=GO_REF:0000002, GO:0005654=Reactome:REACT_9051, GO:0000278=Reactome:REACT_152, GO:0000090=Reactome:REACT_1275, GO:0051301=GO_REF:0000037} Q9NYG5 Anaphase-promoting complex subunit 11 protein 20130301 {GO:0007094=TAS, GO:0004842=IDA, GO:0016567=IDA, GO:0051437=TAS, GO:0051436=TAS, GO:0031145=TAS, GO:0051439=TAS, GO:0005829=TAS, GO:0007067=TAS, GO:0070979=IDA, GO:0005680=IDA, GO:0000087=TAS, GO:0000075=TAS, GO:0008270=IEA, GO:0005654=TAS, GO:0000278=TAS, GO:0000090=TAS, GO:0051301=IEA} M phase of mitotic cell cycle, anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process, cell cycle checkpoint, cell division, mitosis, mitotic anaphase, mitotic cell cycle, mitotic spindle assembly checkpoint, negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle, positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle, protein K11-linked ubiquitination, protein ubiquitination, regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle anaphase-promoting complex, cytosol, nucleoplasm ubiquitin-protein ligase activity, zinc ion binding Human ANAPC13 UniProtKB UniProtKB {GO:0007067=GO_REF:0000037, GO:0070979=PMID:18485873, GO:0005680=PMID:16364912, GO:0051301=GO_REF:0000037} Q9BS18 Anaphase-promoting complex subunit 13 protein 20091027 {GO:0007067=IEA, GO:0070979=IDA, GO:0005680=IDA, GO:0051301=IEA} cell division, mitosis, protein K11-linked ubiquitination anaphase-promoting complex Human ANAPC16 HPA UniProtKB {GO:0005737=GO_REF:0000052, GO:0007067=GO_REF:0000037, GO:0016567=PMID:20360068, GO:0005680=PMID:20360068, GO:0051301=GO_REF:0000037} Q96DE5 Anaphase-promoting complex subunit 16 protein 20110516 {GO:0005737=IDA, GO:0007067=IEA, GO:0016567=IDA, GO:0005680=IDA, GO:0051301=IEA} cell division, mitosis, protein ubiquitination anaphase-promoting complex, cytoplasm Human ANAPC2 Reactome UniProtKB {GO:0007094=Reactome:REACT_2137, GO:0006511=PMID:9469815, GO:0090129=GO_REF:0000024, GO:0004842=PMID:9469815, GO:0051437=Reactome:REACT_6904, GO:0051436=Reactome:REACT_6785, GO:0000079=PMID:9469815, GO:0031145=Reactome:REACT_6871, GO:0051439=Reactome:REACT_6867, GO:0030154=GO_REF:0000037, GO:0005829=Reactome:REACT_9035, GO:0007399=GO_REF:0000037, GO:0008054=PMID:9469815, GO:0031915=GO_REF:0000024, GO:0070979=PMID:18485873, GO:0005680=PMID:16364912, GO:0000087=Reactome:REACT_910, GO:0000075=Reactome:REACT_1538, GO:0005654=Reactome:REACT_9051, GO:0000278=Reactome:REACT_152, GO:0000090=Reactome:REACT_1275, GO:0031625=GO_REF:0000002, GO:0051301=GO_REF:0000037} Q9UJX6 Anaphase-promoting complex subunit 2 protein 20130301 {GO:0007094=TAS, GO:0006511=TAS, GO:0090129=ISS, GO:0004842=TAS, GO:0051437=TAS, GO:0051436=TAS, GO:0000079=TAS, GO:0031145=TAS, GO:0051439=TAS, GO:0030154=IEA, GO:0005829=TAS, GO:0007399=IEA, GO:0008054=TAS, GO:0031915=ISS, GO:0070979=IDA, GO:0005680=IDA, GO:0000087=TAS, GO:0000075=TAS, GO:0005654=TAS, GO:0000278=TAS, GO:0000090=TAS, GO:0031625=IEA, GO:0051301=IEA} M phase of mitotic cell cycle, anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process, cell cycle checkpoint, cell differentiation, cell division, cyclin catabolic process, mitotic anaphase, mitotic cell cycle, mitotic spindle assembly checkpoint, negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle, nervous system development, positive regulation of synapse maturation, positive regulation of synaptic plasticity, positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle, protein K11-linked ubiquitination, regulation of cyclin-dependent protein serine/threonine kinase activity, regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle, ubiquitin-dependent protein catabolic process anaphase-promoting complex, cytosol, nucleoplasm ubiquitin protein ligase binding, ubiquitin-protein ligase activity Human ANAPC4 BHF-UCL UniProtKB {GO:0007094=Reactome:REACT_2137, GO:0006511=PMID:9469815, GO:0004842=PMID:6180011, GO:0019903=PMID:21241890, GO:0051437=Reactome:REACT_6904, GO:0005634=PMID:21241890, GO:0051436=Reactome:REACT_6785, GO:0031145=Reactome:REACT_6871, GO:0051439=Reactome:REACT_6867, GO:0005829=Reactome:REACT_9035, GO:0007067=PMID:9469815, GO:0070979=PMID:18485873, GO:0005680=PMID:21926987, GO:0000086=PMID:9469815, GO:0000087=Reactome:REACT_910, GO:0000075=Reactome:REACT_1538, GO:0005654=Reactome:REACT_9051, GO:0030071=GO_REF:0000002, GO:0000278=Reactome:REACT_152, GO:0000090=Reactome:REACT_1275, GO:0051301=GO_REF:0000037} Q9UJX5 Anaphase-promoting complex subunit 4 protein 20110421 {GO:0007094=TAS, GO:0006511=TAS, GO:0004842=TAS, GO:0019903=IPI, GO:0051437=TAS, GO:0005634=IDA, GO:0051436=TAS, GO:0031145=TAS, GO:0051439=TAS, GO:0005829=TAS, GO:0007067=TAS, GO:0070979=IDA, GO:0005680=IDA, GO:0000086=TAS, GO:0000087=TAS, GO:0000075=TAS, GO:0005654=TAS, GO:0030071=IEA, GO:0000278=TAS, GO:0000090=TAS, GO:0051301=IEA} G2/M transition of mitotic cell cycle, M phase of mitotic cell cycle, anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process, cell cycle checkpoint, cell division, mitosis, mitotic anaphase, mitotic cell cycle, mitotic spindle assembly checkpoint, negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle, positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle, protein K11-linked ubiquitination, regulation of mitotic metaphase/anaphase transition, regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle, ubiquitin-dependent protein catabolic process anaphase-promoting complex, cytosol, nucleoplasm, nucleus protein phosphatase binding, ubiquitin-protein ligase activity Human ANAPC5 BHF-UCL UniProtKB {GO:0006511=PMID:9469815, GO:0007094=Reactome:REACT_2137, GO:0004842=PMID:9469815, GO:0019903=PMID:21241890, GO:0051437=Reactome:REACT_6904, GO:0005634=PMID:21241890, GO:0051436=Reactome:REACT_6785, GO:0031145=Reactome:REACT_6871, GO:0051439=Reactome:REACT_6867, GO:0005829=Reactome:REACT_9035, GO:0070979=PMID:18485873, GO:0005680=PMID:16364912, GO:0000086=PMID:9469815, GO:0000087=Reactome:REACT_910, GO:0000075=Reactome:REACT_1538, GO:0005654=Reactome:REACT_9051, GO:0000278=Reactome:REACT_152, GO:0000090=Reactome:REACT_1275, GO:0051301=GO_REF:0000037} Q9UJX4 Anaphase-promoting complex subunit 5 protein 20110421 {GO:0006511=TAS, GO:0007094=TAS, GO:0004842=TAS, GO:0019903=IPI, GO:0051437=TAS, GO:0005634=IDA, GO:0051436=TAS, GO:0031145=TAS, GO:0051439=TAS, GO:0005829=TAS, GO:0070979=IDA, GO:0005680=IDA, GO:0000086=TAS, GO:0000087=TAS, GO:0000075=TAS, GO:0005654=TAS, GO:0000278=TAS, GO:0000090=TAS, GO:0051301=IEA} G2/M transition of mitotic cell cycle, M phase of mitotic cell cycle, anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process, cell cycle checkpoint, cell division, mitotic anaphase, mitotic cell cycle, mitotic spindle assembly checkpoint, negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle, positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle, protein K11-linked ubiquitination, regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle, ubiquitin-dependent protein catabolic process anaphase-promoting complex, cytosol, nucleoplasm, nucleus protein phosphatase binding, ubiquitin-protein ligase activity Human ANAPC7 BHF-UCL UniProtKB {GO:0007094=Reactome:REACT_2137, GO:0019903=PMID:21241890, GO:0051437=Reactome:REACT_6904, GO:0005634=PMID:21241890, GO:0051436=Reactome:REACT_6785, GO:0031145=Reactome:REACT_6871, GO:0051439=Reactome:REACT_6867, GO:0005829=Reactome:REACT_9035, GO:0070979=PMID:18485873, GO:0005680=PMID:21926987, GO:0000087=Reactome:REACT_910, GO:0000075=Reactome:REACT_1538, GO:0005654=Reactome:REACT_9051, GO:0000278=Reactome:REACT_152, GO:0000090=Reactome:REACT_1275, GO:0051301=GO_REF:0000037} Q9UJX3 Anaphase-promoting complex subunit 7 protein 20110421 {GO:0007094=TAS, GO:0019903=IPI, GO:0051437=TAS, GO:0005634=IDA, GO:0051436=TAS, GO:0031145=TAS, GO:0051439=TAS, GO:0005829=TAS, GO:0070979=IDA, GO:0005680=IDA, GO:0000087=TAS, GO:0000075=TAS, GO:0005654=TAS, GO:0000278=TAS, GO:0000090=TAS, GO:0051301=IEA} M phase of mitotic cell cycle, anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process, cell cycle checkpoint, cell division, mitotic anaphase, mitotic cell cycle, mitotic spindle assembly checkpoint, negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle, positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle, protein K11-linked ubiquitination, regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle anaphase-promoting complex, cytosol, nucleoplasm, nucleus protein phosphatase binding Human ANG IntAct UniProtKB {GO:0005515=PMID:15737636, GO:0017148=GO_REF:0000037, GO:0008219=GO_REF:0000037, GO:0009303=PMID:15735021, GO:0050714=PMID:2646638, GO:0005634=PMID:10649442, GO:0019843=PMID:2457905, GO:0007202=PMID:2457905, GO:0001556=PMID:11438326, GO:0005615=PMID:16490744, GO:0032431=PMID:2646638, GO:0030426=GO_REF:0000024, GO:0001541=PMID:12770725, GO:0007154=PMID:10103013, GO:0032311=PMID:3470787, GO:0032148=PMID:17125737, GO:0030041=GO_REF:0000024, GO:0043025=GO_REF:0000024, GO:0006651=PMID:2457905, GO:0009725=PMID:10999833, GO:0008201=PMID:10103013, GO:0001666=PMID:15776477, GO:0042277=PMID:11782452, GO:0005507=PMID:9245697, GO:0005102=PMID:9122172, GO:0005605=PMID:15166501, GO:0005730=GO_REF:0000024, GO:0042592=PMID:15166501, GO:0048662=PMID:10103013, GO:0004522=GO_REF:0000002, GO:0003779=PMID:7679494, GO:0004540=PMID:2730651, GO:0001890=PMID:11984825, GO:0001525=PMID:8448182, GO:0003677=PMID:10649442, GO:0004519=PMID:10103013, GO:0016477=PMID:17125737, GO:0001938=PMID:9707554, GO:0042327=PMID:17125737} P03950 Angiogenin protein 20130415 {GO:0005515=IPI, GO:0017148=IEA, GO:0008219=IEA, GO:0009303=IMP, GO:0050714=IDA, GO:0005634=IDA, GO:0019843=TAS, GO:0007202=IMP, GO:0001556=NAS, GO:0005615=IDA, GO:0032431=IMP, GO:0030426=ISS, GO:0001541=NAS, GO:0007154=NAS, GO:0032311=IPI, GO:0032148=IMP, GO:0030041=ISS, GO:0043025=ISS, GO:0006651=IDA, GO:0009725=IDA, GO:0008201=IDA, GO:0001666=NAS, GO:0042277=IDA, GO:0005507=IDA, GO:0005102=IDA, GO:0005605=IDA, GO:0005730=ISS, GO:0042592=NAS, GO:0048662=IDA, GO:0004522=IEA, GO:0003779=IDA, GO:0004540=IDA, GO:0001890=NAS, GO:0001525=IDA, GO:0003677=IC, GO:0004519=TAS, GO:0016477=IMP, GO:0001938=IDA, GO:0042327=IDA} actin filament polymerization, activation of phospholipase A2 activity, activation of phospholipase C activity, activation of protein kinase B activity, angiogenesis, cell communication, cell death, cell migration, diacylglycerol biosynthetic process, homeostatic process, negative regulation of smooth muscle cell proliferation, negative regulation of translation, oocyte maturation, ovarian follicle development, placenta development, positive regulation of endothelial cell proliferation, positive regulation of phosphorylation, positive regulation of protein secretion, rRNA transcription, response to hormone stimulus, response to hypoxia angiogenin-PRI complex, basal lamina, extracellular space, growth cone, neuronal cell body, nucleolus, nucleus DNA binding, actin binding, copper ion binding, endonuclease activity, heparin binding, pancreatic ribonuclease activity, peptide binding, protein binding, rRNA binding, receptor binding, ribonuclease activity Human UniProtKB:P35609 ANGEL1 null null {} null null null null {} null null null ANGEL2 null null {} null null null null {} null null null ANGPT1 Reactome UniProtKB {GO:0051897=PMID:18425120, GO:0072012=GO_REF:0000024, GO:0050731=PMID:19689429, GO:0002040=PMID:10218485, GO:0050900=Reactome:REACT_12051, GO:0005615=PMID:8980223, GO:0030154=GO_REF:0000037, GO:0033138=GO_REF:0000019, GO:0007171=PMID:19424712, GO:0031398=PMID:19689429, GO:0070374=PMID:18425120, GO:0030097=GO_REF:0000019, GO:0030971=PMID:19922791, GO:0043066=PMID:10218485, GO:0048014=PMID:19922791, GO:0031589=GO_REF:0000019, GO:0005102=GO_REF:0000019, GO:0005576=Reactome:REACT_16914, GO:0014068=GO_REF:0000019, GO:0001525=GO_REF:0000019, GO:0001701=GO_REF:0000019, GO:0045785=GO_REF:0000019, GO:0010595=PMID:12958144, GO:0007162=PMID:19674970, GO:0007596=Reactome:REACT_604, GO:0001936=PMID:8980223, GO:0034394=PMID:19615361, GO:0045121=PMID:19615361, GO:0014842=PMID:19733541, GO:2000352=PMID:19674970, GO:0007169=GO_REF:0000019, GO:0043116=PMID:14978158, GO:0002092=PMID:19424712, GO:0030210=PMID:19297368} Q15389 Angiopoietin-1 protein 20071203 {GO:0051897=IDA, GO:0072012=ISS, GO:0050731=IDA, GO:0002040=IDA, GO:0050900=TAS, GO:0005615=IDA, GO:0030154=IEA, GO:0033138=IEA, GO:0007171=IDA, GO:0031398=IDA, GO:0070374=IDA, GO:0030097=IEA, GO:0030971=IPI, GO:0043066=IDA, GO:0048014=IDA, GO:0031589=IEA, GO:0005102=IEA, GO:0005576=TAS, GO:0014068=IEA, GO:0001525=IEA, GO:0001701=IEA, GO:0045785=IEA, GO:0010595=IDA, GO:0007162=IDA, GO:0007596=TAS, GO:0001936=IDA, GO:0034394=IDA, GO:0045121=IDA, GO:0014842=IDA, GO:2000352=IDA, GO:0007169=IEA, GO:0043116=IDA, GO:0002092=IDA, GO:0030210=IDA} Tie signaling pathway, activation of transmembrane receptor protein tyrosine kinase activity, angiogenesis, blood coagulation, cell differentiation, cell-substrate adhesion, glomerulus vasculature development, hemopoiesis, heparin biosynthetic process, in utero embryonic development, leukocyte migration, negative regulation of apoptotic process, negative regulation of cell adhesion, negative regulation of endothelial cell apoptotic process, negative regulation of vascular permeability, positive regulation of ERK1 and ERK2 cascade, positive regulation of cell adhesion, positive regulation of endothelial cell migration, positive regulation of peptidyl-serine phosphorylation, positive regulation of peptidyl-tyrosine phosphorylation, positive regulation of phosphatidylinositol 3-kinase cascade, positive regulation of protein kinase B signaling cascade, positive regulation of protein ubiquitination, positive regulation of receptor internalization, protein localization to cell surface, regulation of endothelial cell proliferation, regulation of satellite cell proliferation, sprouting angiogenesis, transmembrane receptor protein tyrosine kinase signaling pathway extracellular region, extracellular space, membrane raft receptor binding, receptor tyrosine kinase binding Human ANGPT2 IntAct UniProtKB {GO:0005515=PMID:20708158, GO:0014070=GO_REF:0000019, GO:0005886=GO_REF:0000019, GO:0031100=GO_REF:0000019, GO:0072012=GO_REF:0000024, GO:0010812=GO_REF:0000019, GO:0005634=GO_REF:0000019, GO:0042995=GO_REF:0000019, GO:0050900=Reactome:REACT_12051, GO:0007281=GO_REF:0000019, GO:0005615=PMID:9660821, GO:0046872=GO_REF:0000037, GO:0009314=GO_REF:0000019, GO:0014823=GO_REF:0000019, GO:0001666=GO_REF:0000019, GO:0030971=PMID:19922791, GO:0048014=PMID:19922791, GO:0060135=GO_REF:0000019, GO:0005102=PMID:10766762, GO:0005576=Reactome:REACT_12547, GO:0001525=GO_REF:0000019, GO:0045766=GO_REF:0000019, GO:0009749=GO_REF:0000019, GO:0009612=GO_REF:0000019, GO:0007165=PMID:10766762, GO:0071363=GO_REF:0000019, GO:0007596=Reactome:REACT_604, GO:0016525=GO_REF:0000019, GO:0043537=PMID:9660821} O15123 Angiopoietin-2 protein 20130415 {GO:0005515=IPI, GO:0014070=IEA, GO:0005886=IEA, GO:0031100=IEA, GO:0072012=ISS, GO:0010812=IEA, GO:0005634=IEA, GO:0042995=IEA, GO:0050900=TAS, GO:0007281=IEA, GO:0005615=IDA, GO:0046872=IEA, GO:0009314=IEA, GO:0014823=IEA, GO:0001666=IEA, GO:0030971=IPI, GO:0048014=IDA, GO:0060135=IEA, GO:0005102=TAS, GO:0005576=TAS, GO:0001525=IEA, GO:0045766=IEA, GO:0009749=IEA, GO:0009612=IEA, GO:0007165=TAS, GO:0071363=IEA, GO:0007596=TAS, GO:0016525=IEA, GO:0043537=IDA} Tie signaling pathway, angiogenesis, blood coagulation, cellular response to growth factor stimulus, germ cell development, glomerulus vasculature development, leukocyte migration, maternal process involved in female pregnancy, negative regulation of angiogenesis, negative regulation of blood vessel endothelial cell migration, negative regulation of cell-substrate adhesion, organ regeneration, positive regulation of angiogenesis, response to activity, response to glucose stimulus, response to hypoxia, response to mechanical stimulus, response to organic cyclic compound, response to radiation, signal transduction cell projection, extracellular region, extracellular space, nucleus, plasma membrane metal ion binding, protein binding, receptor binding, receptor tyrosine kinase binding Human UniProtKB:Q02763 ANGPT4 GOC UniProtKB {GO:0030971=PMID:10051567, GO:0043066=PMID:12958144, GO:0050731=PMID:15851516, GO:0071456=PMID:12958144, GO:0005576=Reactome:REACT_12598, GO:0001525=GO_REF:0000037, GO:0050900=Reactome:REACT_12051, GO:0005615=PMID:10025962, GO:0045766=PMID:15284220, GO:0010595=PMID:12958144, GO:0043536=PMID:15284220, GO:0007171=PMID:15851516, GO:0030297=PMID:10051567, GO:0007596=Reactome:REACT_604, GO:0001935=PMID:10025962, GO:0016525=PMID:16790085, GO:0043537=PMID:16790085} Q9Y264 Angiopoietin-4 protein 20130413 {GO:0030971=IDA, GO:0043066=IDA, GO:0050731=IDA, GO:0071456=IEP, GO:0005576=TAS, GO:0001525=IEA, GO:0050900=TAS, GO:0005615=IDA, GO:0045766=IDA, GO:0010595=IDA, GO:0043536=IDA, GO:0007171=IDA, GO:0030297=IDA, GO:0007596=TAS, GO:0001935=IDA, GO:0016525=IDA, GO:0043537=IDA} activation of transmembrane receptor protein tyrosine kinase activity, angiogenesis, blood coagulation, cellular response to hypoxia, endothelial cell proliferation, leukocyte migration, negative regulation of angiogenesis, negative regulation of apoptotic process, negative regulation of blood vessel endothelial cell migration, positive regulation of angiogenesis, positive regulation of blood vessel endothelial cell migration, positive regulation of endothelial cell migration, positive regulation of peptidyl-tyrosine phosphorylation extracellular region, extracellular space receptor tyrosine kinase binding, transmembrane receptor protein tyrosine kinase activator activity Human ANGPTL1 MGI UniProtKB {GO:0005102=GO_REF:0000019, GO:0005615=PMID:10025962, GO:0007169=GO_REF:0000019} O95841 Angiopoietin-related protein 1 protein 20060110 {GO:0005102=IEA, GO:0005615=IDA, GO:0007169=IEA} transmembrane receptor protein tyrosine kinase signaling pathway extracellular space receptor binding Human ANGPTL3 BHF-UCL UniProtKB {GO:0043498=PMID:12565906, GO:0050996=PMID:12565906, GO:0019915=PMID:12565906, GO:0070328=GO_REF:0000024, GO:0048844=GO_REF:0000024, GO:0006071=PMID:12565906, GO:0005615=PMID:17110602, GO:0006631=PMID:12565906, GO:0009725=GO_REF:0000019, GO:0008203=PMID:17110602, GO:0004857=GO_REF:0000024, GO:0042632=PMID:17110602, GO:0004859=PMID:17110602, GO:0030335=PMID:11877390, GO:0055088=PMID:17110602, GO:0045766=PMID:11877390, GO:0010519=PMID:17110602, GO:0051005=PMID:17110602, GO:0007165=PMID:11877390, GO:0005178=PMID:11877390, GO:0007160=PMID:11877390, GO:0007229=PMID:11877390, GO:0055091=PMID:17110602, GO:0055090=PMID:17110602, GO:0006644=PMID:17110602, GO:0008083=PMID:11877390, GO:0009395=PMID:17110602} Q9Y5C1 Angiopoietin-related protein 3 protein 20080121 {GO:0043498=IDA, GO:0050996=IDA, GO:0019915=IDA, GO:0070328=ISS, GO:0048844=ISS, GO:0006071=IDA, GO:0005615=IDA, GO:0006631=IDA, GO:0009725=IEA, GO:0008203=IDA, GO:0004857=ISS, GO:0042632=IDA, GO:0004859=IDA, GO:0030335=IDA, GO:0055088=IDA, GO:0045766=IDA, GO:0010519=IDA, GO:0051005=IDA, GO:0007165=IDA, GO:0005178=IPI, GO:0007160=IPI, GO:0007229=NAS, GO:0055091=IDA, GO:0055090=IDA, GO:0006644=IDA, GO:0008083=IDA, GO:0009395=IDA} acylglycerol homeostasis, artery morphogenesis, cell-matrix adhesion, cholesterol homeostasis, cholesterol metabolic process, fatty acid metabolic process, glycerol metabolic process, integrin-mediated signaling pathway, lipid homeostasis, lipid storage, negative regulation of lipoprotein lipase activity, negative regulation of phospholipase activity, phospholipid catabolic process, phospholipid homeostasis, phospholipid metabolic process, positive regulation of angiogenesis, positive regulation of cell migration, positive regulation of lipid catabolic process, response to hormone stimulus, signal transduction, triglyceride homeostasis extracellular space cell surface binding, enzyme inhibitor activity, growth factor activity, integrin binding, phospholipase inhibitor activity Human ANGPTL4 BHF-UCL UniProtKB {GO:0005515=PMID:21397862, GO:0004857=GO_REF:0000024, GO:0001666=PMID:12707035, GO:0043066=PMID:10698685, GO:0005578=GO_REF:0000039, GO:0070328=GO_REF:0000024, GO:0005576=Reactome:REACT_27173, GO:0044281=Reactome:REACT_111217, GO:0001525=GO_REF:0000037, GO:0005615=PMID:10698685, GO:0030154=GO_REF:0000037, GO:0045766=PMID:11953136, GO:0051005=PMID:19542565, GO:0051260=GO_REF:0000019, GO:0044255=Reactome:REACT_22279} Q9BY76 Angiopoietin-related protein 4 protein 20100506 {GO:0005515=IPI, GO:0004857=ISS, GO:0001666=NAS, GO:0043066=IDA, GO:0005578=IEA, GO:0070328=ISS, GO:0005576=TAS, GO:0044281=TAS, GO:0001525=IEA, GO:0005615=IDA, GO:0030154=IEA, GO:0045766=TAS, GO:0051005=IDA, GO:0051260=IEA, GO:0044255=TAS} angiogenesis, cell differentiation, cellular lipid metabolic process, negative regulation of apoptotic process, negative regulation of lipoprotein lipase activity, positive regulation of angiogenesis, protein homooligomerization, response to hypoxia, small molecule metabolic process, triglyceride homeostasis extracellular region, extracellular space, proteinaceous extracellular matrix enzyme inhibitor activity, protein binding Human UniProtKB:Q9Z1P8 ANGPTL7 PINC UniProtKB {GO:0005576=GO_REF:0000039, GO:0006979=PMID:8026862} O43827 Angiopoietin-related protein 7 protein 20030904 {GO:0005576=IEA, GO:0006979=TAS} response to oxidative stress extracellular region Human ANK1 BHF-UCL UniProtKB {GO:0005515=PMID:379653, GO:0005886=PMID:379653, GO:0072661=PMID:18768923, GO:0006887=PMID:1833445, GO:0005829=Reactome:REACT_22248, GO:0016323=PMID:12409278, GO:0007411=Reactome:REACT_18266, GO:0048821=GO_REF:0000019, GO:0007010=PMID:9430667, GO:0051117=PMID:8159688, GO:0005856=PMID:1833445, GO:0008093=PMID:379653, GO:0030507=PMID:8159688, GO:0014731=PMID:379653, GO:0031430=GO_REF:0000039, GO:0045199=PMID:11427698, GO:0015672=GO_REF:0000019, GO:0006888=PMID:18768923, GO:0007165=GO_REF:0000002, GO:0016529=GO_REF:0000039, GO:0006779=GO_REF:0000019, GO:0005198=PMID:9430667, GO:0005200=PMID:8640229, GO:0030863=GO_REF:0000019, GO:0019899=PMID:21177872} P16157 Ankyrin-1 protein 20120607 {GO:0005515=IPI, GO:0005886=IDA, GO:0072661=IMP, GO:0006887=NAS, GO:0005829=TAS, GO:0016323=NAS, GO:0007411=TAS, GO:0048821=IEA, GO:0007010=NAS, GO:0051117=IPI, GO:0005856=NAS, GO:0008093=IDA, GO:0030507=IPI, GO:0014731=IDA, GO:0031430=IEA, GO:0045199=TAS, GO:0015672=IEA, GO:0006888=IDA, GO:0007165=IEA, GO:0016529=IEA, GO:0006779=IEA, GO:0005198=NAS, GO:0005200=TAS, GO:0030863=IEA, GO:0019899=IPI} ER to Golgi vesicle-mediated transport, axon guidance, cytoskeleton organization, erythrocyte development, exocytosis, maintenance of epithelial cell apical/basal polarity, monovalent inorganic cation transport, porphyrin-containing compound biosynthetic process, protein targeting to plasma membrane, signal transduction M band, basolateral plasma membrane, cortical cytoskeleton, cytoskeleton, cytosol, plasma membrane, sarcoplasmic reticulum, spectrin-associated cytoskeleton ATPase binding, cytoskeletal adaptor activity, enzyme binding, protein binding, spectrin binding, structural constituent of cytoskeleton, structural molecule activity Human ANK2 BHF-UCL UniProtKB {GO:0005515=PMID:21859974, GO:0030018=GO_REF:0000024, GO:0003283=PMID:18832177, GO:0051928=GO_REF:0000024, GO:0043268=GO_REF:0000019, GO:0015459=GO_REF:0000019, GO:0086070=PMID:21859974, GO:0060307=PMID:18832177, GO:2001259=GO_REF:0000019, GO:0060048=GO_REF:0000019, GO:0086066=GO_REF:0000024, GO:0007411=Reactome:REACT_18266, GO:0045211=GO_REF:0000039, GO:0051924=PMID:12571597, GO:0051117=GO_REF:0000019, GO:0030674=GO_REF:0000019, GO:0005856=GO_REF:0000039, GO:0086004=PMID:17242276, GO:0086005=PMID:17242276, GO:0019901=PMID:18782775, GO:0030507=PMID:15262991, GO:0031430=GO_REF:0000019, GO:0033292=GO_REF:0000019, GO:0044325=PMID:21859974, GO:0002027=PMID:18832177, GO:0005887=GO_REF:0000019, GO:1901018=GO_REF:0000019, GO:0055117=PMID:15178757, GO:0043034=GO_REF:0000019, GO:0086014=PMID:21859974, GO:0019899=PMID:21177872, GO:0031672=GO_REF:0000024, GO:0086015=GO_REF:0000024, GO:0048471=GO_REF:0000019, GO:1901021=GO_REF:0000019, GO:0005886=GO_REF:0000024, GO:0072661=GO_REF:0000019, GO:0070296=PMID:19098452, GO:0086091=PMID:21859974, GO:0005829=Reactome:REACT_22229, GO:0016323=PMID:15611082, GO:0016324=GO_REF:0000039, GO:0031647=PMID:18832177, GO:0014704=GO_REF:0000019, GO:0086046=PMID:19098452, GO:0033365=PMID:15178757, GO:0006874=GO_REF:0000024, GO:0010882=PMID:12571597, GO:0050821=GO_REF:0000019, GO:0010881=PMID:21859974, GO:0030315=GO_REF:0000019, GO:0070972=PMID:15178757, GO:0072659=GO_REF:0000024, GO:0010628=GO_REF:0000019, GO:0007165=GO_REF:0000002, GO:0034394=GO_REF:0000024} Q01484 Ankyrin-2 protein 20120608 {GO:0005515=IPI, GO:0030018=ISS, GO:0003283=IMP, GO:0051928=ISS, GO:0043268=IEA, GO:0015459=IEA, GO:0086070=IMP, GO:0060307=IMP, GO:2001259=IEA, GO:0060048=IEA, GO:0086066=ISS, GO:0007411=TAS, GO:0045211=IEA, GO:0051924=IGI, GO:0051117=IEA, GO:0030674=IEA, GO:0005856=IEA, GO:0086004=IGI, GO:0086005=IMP, GO:0019901=IPI, GO:0030507=IPI, GO:0031430=IEA, GO:0033292=IEA, GO:0044325=IPI, GO:0002027=IMP, GO:0005887=IEA, GO:1901018=IEA, GO:0055117=IMP, GO:0043034=IEA, GO:0086014=IMP, GO:0019899=IPI, GO:0031672=ISS, GO:0086015=ISS, GO:0048471=IEA, GO:1901021=IEA, GO:0005886=ISS, GO:0072661=IEA, GO:0070296=TAS, GO:0086091=IMP, GO:0005829=TAS, GO:0016323=IDA, GO:0016324=IEA, GO:0031647=IC, GO:0014704=IEA, GO:0086046=TAS, GO:0033365=IGI, GO:0006874=ISS, GO:0010882=IMP, GO:0050821=IEA, GO:0010881=ISS, GO:0030315=IEA, GO:0070972=IGI, GO:0072659=ISS, GO:0010628=IEA, GO:0007165=IEA, GO:0034394=ISS} SA node cell to atrial cardiac muscle cell communication, T-tubule organization, atrial cardiac muscle cell to AV node cell communication, atrial septum development, axon guidance, cardiac muscle contraction, cellular calcium ion homeostasis, membrane depolarization involved in regulation of SA node cell action potential, positive regulation of calcium ion transmembrane transporter activity, positive regulation of calcium ion transport, positive regulation of cation channel activity, positive regulation of gene expression, positive regulation of potassium ion transmembrane transporter activity, positive regulation of potassium ion transport, protein localization to cell surface, protein localization to endoplasmic reticulum, protein localization to organelle, protein localization to plasma membrane, protein stabilization, protein targeting to plasma membrane, regulation of SA node cell action potential, regulation of atrial cardiac muscle cell action potential, regulation of calcium ion transport, regulation of cardiac muscle cell contraction, regulation of cardiac muscle contraction, regulation of cardiac muscle contraction by calcium ion signaling, regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion, regulation of heart rate, regulation of heart rate by cardiac conduction, regulation of protein stability, regulation of ventricular cardiac muscle cell action potential, regulation of ventricular cardiac muscle cell membrane repolarization, sarcoplasmic reticulum calcium ion transport, signal transduction A band, M band, T-tubule, Z disc, apical plasma membrane, basolateral plasma membrane, costamere, cytoskeleton, cytosol, integral to plasma membrane, intercalated disc, perinuclear region of cytoplasm, plasma membrane, postsynaptic membrane ATPase binding, enzyme binding, ion channel binding, potassium channel regulator activity, protein binding, protein binding, bridging, protein kinase binding, spectrin binding Human UniProtKB:Q8C8R3 ANK3 BHF-UCL UniProtKB {GO:0005515=PMID:15611082, GO:0008092=PMID:21223964, GO:0007009=PMID:17620337, GO:0072660=PMID:17620337, GO:0005886=GO_REF:0000024, GO:2000651=PMID:18180363, GO:0043001=PMID:17620337, GO:0072661=GO_REF:0000019, GO:0045202=GO_REF:0000019, GO:0007409=GO_REF:0000024, GO:0043266=GO_REF:0000024, GO:0005764=GO_REF:0000039, GO:0019228=GO_REF:0000024, GO:0045184=PMID:15611082, GO:0043194=GO_REF:0000024, GO:0016323=PMID:15611082, GO:0009925=PMID:21223964, GO:0014704=GO_REF:0000019, GO:0007411=GO_REF:0000019, GO:0045211=GO_REF:0000039, GO:0030674=GO_REF:0000024, GO:0045296=GO_REF:0000024, GO:0009986=PMID:21223964, GO:0000281=PMID:17620337, GO:0030507=GO_REF:0000024, GO:0014731=GO_REF:0000024, GO:0044325=GO_REF:0000024, GO:0042383=PMID:21223964, GO:0010628=PMID:18180363, GO:0007165=GO_REF:0000002, GO:0033268=GO_REF:0000024, GO:0050808=GO_REF:0000019, GO:0016020=GO_REF:0000019, GO:0043034=PMID:21223964, GO:0005200=PMID:17620337} Q12955 Ankyrin-3 protein 20120607 {GO:0005515=IPI, GO:0008092=ISS, GO:0007009=IMP, GO:0072660=IGI, GO:0005886=ISS, GO:2000651=ISS, GO:0043001=IMP, GO:0072661=IEA, GO:0045202=IEA, GO:0007409=ISS, GO:0043266=ISS, GO:0005764=IEA, GO:0019228=ISS, GO:0045184=IMP, GO:0043194=ISS, GO:0016323=IDA, GO:0009925=IDA, GO:0014704=IEA, GO:0007411=IEA, GO:0045211=IEA, GO:0030674=ISS, GO:0045296=ISS, GO:0009986=ISS, GO:0000281=IMP, GO:0030507=ISS, GO:0014731=ISS, GO:0044325=ISS, GO:0042383=IDA, GO:0010628=ISS, GO:0007165=IEA, GO:0033268=ISS, GO:0050808=IEA, GO:0016020=IEA, GO:0043034=TAS, GO:0005200=IMP} Golgi to plasma membrane protein transport, axon guidance, axonogenesis, cytokinesis after mitosis, establishment of protein localization, maintenance of protein location in plasma membrane, plasma membrane organization, positive regulation of gene expression, positive regulation of sodium ion transmembrane transporter activity, protein targeting to plasma membrane, regulation of action potential in neuron, regulation of potassium ion transport, signal transduction, synapse organization axon initial segment, basal plasma membrane, basolateral plasma membrane, cell surface, costamere, intercalated disc, lysosome, membrane, node of Ranvier, plasma membrane, postsynaptic membrane, sarcolemma, spectrin-associated cytoskeleton, synapse cadherin binding, cytoskeletal protein binding, ion channel binding, protein binding, protein binding, bridging, spectrin binding, structural constituent of cytoskeleton Human UniProtKB:G5E8K5 ANKAR UniProtKB UniProtKB {GO:0016021=GO_REF:0000037} Q7Z5J8 Ankyrin and armadillo repeat-containing protein protein 20130413 {GO:0016021=IEA} integral to membrane Human UniProtKB-KW:KW-0812 ANKFY1 HPA UniProtKB {GO:0005515=PMID:20562859, GO:0046872=GO_REF:0000037, GO:0010008=GO_REF:0000024, GO:0043231=GO_REF:0000052} Q9P2R3 Ankyrin repeat and FYVE domain-containing protein 1 protein 20101115 {GO:0005515=IPI, GO:0046872=IEA, GO:0010008=ISS, GO:0043231=IDA} endosome membrane, intracellular membrane-bounded organelle metal ion binding, protein binding Human ANKH GOC UniProtKB {GO:0001501=PMID:10894769, GO:0030500=GO_REF:0000024, GO:0005886=GO_REF:0000024, GO:0005887=GO_REF:0000024, GO:0019867=PMID:11326272, GO:0015114=GO_REF:0000002, GO:0007626=PMID:10894769, GO:0005315=PMID:11326272, GO:0016021=PMID:11326272, GO:0030504=PMID:11326272, GO:0030505=PMID:11326272} Q9HCJ1 Progressive ankylosis protein homolog protein 20130413 {GO:0001501=NAS, GO:0030500=ISS, GO:0005886=ISS, GO:0005887=ISS, GO:0019867=TAS, GO:0015114=IEA, GO:0007626=NAS, GO:0005315=IDA, GO:0016021=IDA, GO:0030504=IDA, GO:0030505=IDA} inorganic diphosphate transport, locomotory behavior, regulation of bone mineralization, skeletal system development integral to membrane, integral to plasma membrane, outer membrane, plasma membrane inorganic diphosphate transmembrane transporter activity, inorganic phosphate transmembrane transporter activity, phosphate ion transmembrane transporter activity Human ANKHD1 HPA UniProtKB {GO:0005737=GO_REF:0000052, GO:0003723=GO_REF:0000037, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052} Q8IWZ3 Ankyrin repeat and KH domain-containing protein 1 protein 20100326 {GO:0005737=IDA, GO:0003723=IEA, GO:0005730=IDA, GO:0005634=IDA} cytoplasm, nucleolus, nucleus RNA binding Human ANKIB1 IntAct UniProtKB {GO:0005515=PMID:20195357, GO:0008270=GO_REF:0000002} Q9P2G1 Ankyrin repeat and IBR domain-containing protein 1 protein 20130415 {GO:0005515=IPI, GO:0008270=IEA} protein binding, zinc ion binding Human UniProtKB:P22736 ANKLE1 null null {} null null null null {} null null null ANKLE2 HPA UniProtKB {GO:0005515=PMID:22770216, GO:0007084=Reactome:REACT_160113, GO:0035307=PMID:22770216, GO:0008601=PMID:22770216, GO:0030176=PMID:22770216, GO:0042326=PMID:22770216, GO:0005737=GO_REF:0000052, GO:0050790=PMID:22770216, GO:0000087=Reactome:REACT_910, GO:0005789=Reactome:REACT_160159, GO:0000278=Reactome:REACT_152, GO:0051721=PMID:22770216, GO:0000090=Reactome:REACT_1275, GO:0051301=GO_REF:0000037} Q86XL3 Ankyrin repeat and LEM domain-containing protein 2 protein 20080818 {GO:0005515=IPI, GO:0007084=TAS, GO:0035307=IDA, GO:0008601=TAS, GO:0030176=IDA, GO:0042326=IDA, GO:0005737=IDA, GO:0050790=TAS, GO:0000087=TAS, GO:0005789=TAS, GO:0000278=TAS, GO:0051721=IDA, GO:0000090=TAS, GO:0051301=IEA} M phase of mitotic cell cycle, cell division, mitotic anaphase, mitotic cell cycle, mitotic nuclear envelope reassembly, negative regulation of phosphorylation, positive regulation of protein dephosphorylation, regulation of catalytic activity cytoplasm, endoplasmic reticulum membrane, integral to endoplasmic reticulum membrane protein binding, protein phosphatase 2A binding, protein phosphatase type 2A regulator activity Human ANKMY2 UniProtKB UniProtKB {GO:0005929=GO_REF:0000039, GO:0008270=GO_REF:0000002} Q8IV38 Ankyrin repeat and MYND domain-containing protein 2 protein 20130413 {GO:0005929=IEA, GO:0008270=IEA} cilium zinc ion binding Human UniProtKB-SubCell:SL-0066 ANKRA2 UniProtKB UniProtKB {GO:0008150=GO_REF:0000015, GO:0016020=PMID:11095640, GO:0042826=GO_REF:0000019, GO:0030169=PMID:11095640, GO:0005634=GO_REF:0000019, GO:0005856=GO_REF:0000039, GO:0005829=PMID:11095640} Q9H9E1 Ankyrin repeat family A protein 2 protein 20061026 {GO:0008150=ND, GO:0016020=IDA, GO:0042826=IEA, GO:0030169=IDA, GO:0005634=IEA, GO:0005856=IEA, GO:0005829=IDA} biological_process cytoskeleton, cytosol, membrane, nucleus histone deacetylase binding, low-density lipoprotein particle binding Human ANKRD1 GOC UniProtKB {GO:0005515=PMID:19608030, GO:0042826=PMID:20599664, GO:0071560=PMID:11139470, GO:0005634=PMID:19608030, GO:0044281=Reactome:REACT_111217, GO:0005829=PMID:19608030, GO:0002039=PMID:20599664, GO:0005737=PMID:12054667, GO:0045944=PMID:20599664, GO:0071356=PMID:7730328, GO:0001085=PMID:20599664, GO:0055008=PMID:19608030, GO:0044255=Reactome:REACT_22279, GO:0005667=GO_REF:0000019, GO:0001105=PMID:20599664, GO:0043065=PMID:15805281, GO:0003714=PMID:20599664, GO:0045214=PMID:11309420, GO:0071456=GO_REF:0000019, GO:0035994=PMID:19608030, GO:0070412=PMID:20599664, GO:0000122=GO_REF:0000019, GO:0035690=GO_REF:0000019, GO:0003677=PMID:7730328, GO:0031432=PMID:14583192, GO:0071407=GO_REF:0000019, GO:0071222=PMID:7730328, GO:0010976=GO_REF:0000019, GO:0071347=PMID:7730328, GO:0043517=PMID:20599664, GO:2000279=PMID:11139470, GO:0005654=Reactome:REACT_115878, GO:0031674=PMID:19525294} Q15327 Ankyrin repeat domain-containing protein 1 protein 20130413 {GO:0005515=IPI, GO:0042826=IPI, GO:0071560=IDA, GO:0005634=IDA, GO:0044281=TAS, GO:0005829=IDA, GO:0002039=IPI, GO:0005737=IDA, GO:0045944=IDA, GO:0071356=IDA, GO:0001085=IPI, GO:0055008=IMP, GO:0044255=TAS, GO:0005667=IEA, GO:0001105=IDA, GO:0043065=IMP, GO:0003714=TAS, GO:0045214=NAS, GO:0071456=IEA, GO:0035994=IMP, GO:0070412=IPI, GO:0000122=IEA, GO:0035690=IEA, GO:0003677=IDA, GO:0031432=IPI, GO:0071407=IEA, GO:0071222=IDA, GO:0010976=IEA, GO:0071347=IDA, GO:0043517=IDA, GO:2000279=IMP, GO:0005654=TAS, GO:0031674=ISS} cardiac muscle tissue morphogenesis, cellular lipid metabolic process, cellular response to drug, cellular response to hypoxia, cellular response to interleukin-1, cellular response to lipopolysaccharide, cellular response to organic cyclic compound, cellular response to transforming growth factor beta stimulus, cellular response to tumor necrosis factor, negative regulation of DNA biosynthetic process, negative regulation of transcription from RNA polymerase II promoter, positive regulation of DNA damage response, signal transduction by p53 class mediator, positive regulation of apoptotic process, positive regulation of neuron projection development, positive regulation of transcription from RNA polymerase II promoter, response to muscle stretch, sarcomere organization, small molecule metabolic process I band, cytoplasm, cytosol, nucleoplasm, nucleus, transcription factor complex DNA binding, R-SMAD binding, RNA polymerase II transcription coactivator activity, RNA polymerase II transcription factor binding, histone deacetylase binding, p53 binding, protein binding, titin binding, transcription corepressor activity Human ANKRD10 null null {} null null null null {} null null null ANKRD11 MGI UniProtKB {GO:0060348=GO_REF:0000019, GO:0060325=PMID:21782149, GO:0035264=GO_REF:0000019, GO:0001894=GO_REF:0000019, GO:0048705=PMID:21782149, GO:0042475=PMID:21782149, GO:0005634=PMID:21782149, GO:0001701=GO_REF:0000019} Q6UB99 Ankyrin repeat domain-containing protein 11 protein 20121106 {GO:0060348=IEA, GO:0060325=IMP, GO:0035264=IEA, GO:0001894=IEA, GO:0048705=IMP, GO:0042475=IMP, GO:0005634=IDA, GO:0001701=IEA} bone development, face morphogenesis, in utero embryonic development, multicellular organism growth, odontogenesis of dentin-containing tooth, skeletal system morphogenesis, tissue homeostasis nucleus Human ANKRD12 HPA UniProtKB {GO:0005737=GO_REF:0000052, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052} Q6UB98 Ankyrin repeat domain-containing protein 12 protein 20110516 {GO:0005737=IDA, GO:0005730=IDA, GO:0005634=IDA} cytoplasm, nucleolus, nucleus Human ANKRD13A null null {} null null null null {} null null null ANKRD13B null null {} null null null null {} null null null ANKRD13C BHF-UCL UniProtKB {GO:0010869=PMID:20959461, GO:0048471=PMID:20959461, GO:0005783=PMID:20959461, GO:0005102=PMID:20959461, GO:0005789=GO_REF:0000039, GO:2000209=PMID:20959461, GO:0006621=PMID:20959461} Q8N6S4 Ankyrin repeat domain-containing protein 13C protein 20101028 {GO:0010869=IDA, GO:0048471=IDA, GO:0005783=IDA, GO:0005102=IPI, GO:0005789=IEA, GO:2000209=IDA, GO:0006621=IMP} protein retention in ER lumen, regulation of anoikis, regulation of receptor biosynthetic process endoplasmic reticulum, endoplasmic reticulum membrane, perinuclear region of cytoplasm receptor binding Human ANKRD13D null null {} null null null null {} null null null ANKRD17 HPA UniProtKB {GO:0005737=GO_REF:0000052, GO:0051151=GO_REF:0000019, GO:0019048=GO_REF:0000037, GO:0003723=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0001955=GO_REF:0000019} O75179 Ankyrin repeat domain-containing protein 17 protein 20111111 {GO:0005737=IDA, GO:0051151=IEA, GO:0019048=IEA, GO:0003723=IEA, GO:0005634=IEA, GO:0001955=IEA} blood vessel maturation, negative regulation of smooth muscle cell differentiation, virus-host interaction cytoplasm, nucleus RNA binding Human ANKRD18A null null {} null null null null {} null null null ANKRD18B null null {} null null null null {} null null null ANKRD2 HPA UniProtKB {GO:0007517=PMID:11444853, GO:0006936=PMID:10873377, GO:0008307=PMID:11444853, GO:0031674=GO_REF:0000019, GO:0031432=GO_REF:0000019, GO:0043231=GO_REF:0000052} Q9GZV1 Ankyrin repeat domain-containing protein 2 protein 20111111 {GO:0007517=NAS, GO:0006936=NAS, GO:0008307=NAS, GO:0031674=IEA, GO:0031432=IEA, GO:0043231=IDA} muscle contraction, muscle organ development I band, intracellular membrane-bounded organelle structural constituent of muscle, titin binding Human ANKRD22 null null {} null null null null {} null null null ANKRD23 HPA UniProtKB {GO:0005737=GO_REF:0000052, GO:0005730=GO_REF:0000052, GO:0006631=GO_REF:0000019, GO:0005634=GO_REF:0000052, GO:0015629=GO_REF:0000052, GO:0031432=PMID:14583192, GO:0031674=GO_REF:0000019} Q86SG2 Ankyrin repeat domain-containing protein 23 protein 20110516 {GO:0005737=IDA, GO:0005730=IDA, GO:0006631=IEA, GO:0005634=IDA, GO:0015629=IDA, GO:0031432=IPI, GO:0031674=IEA} fatty acid metabolic process I band, actin cytoskeleton, cytoplasm, nucleolus, nucleus titin binding Human ANKRD24 null null {} null null null null {} null null null ANKRD26 UniProtKB UniProtKB {GO:0005813=PMID:21399614} Q9UPS8 Ankyrin repeat domain-containing protein 26 protein 20110517 {GO:0005813=IDA} centrosome Human ANKRD27 IntAct UniProtKB {GO:0005515=PMID:22705394, GO:0005085=PMID:16525121, GO:0045022=PMID:16525121, GO:0005764=GO_REF:0000054, GO:0005769=PMID:16525121, GO:0005096=GO_REF:0000037} Q96NW4 Ankyrin repeat domain-containing protein 27 protein 20130415 {GO:0005515=IPI, GO:0005085=IDA, GO:0045022=IDA, GO:0005764=IDA, GO:0005769=IDA, GO:0005096=IEA} early endosome to late endosome transport early endosome, lysosome GTPase activator activity, guanyl-nucleotide exchange factor activity, protein binding Human UniProtKB:Q13439 ANKRD28 IntAct UniProtKB {GO:0005515=PMID:18186651, GO:0005654=GO_REF:0000039} O15084 Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A protein 20130415 {GO:0005515=IPI, GO:0005654=IEA} nucleoplasm protein binding Human UniProtKB:Q9UPN7 ANKRD30A UniProtKB UniProtKB {GO:0006355=PMID:11280766, GO:0003700=PMID:11280766, GO:0005634=PMID:11280766, GO:0003677=PMID:11280766} Q9BXX3 Ankyrin repeat domain-containing protein 30A protein 20010919 {GO:0006355=NAS, GO:0003700=NAS, GO:0005634=NAS, GO:0003677=NAS} regulation of transcription, DNA-dependent nucleus DNA binding, sequence-specific DNA binding transcription factor activity Human ANKRD32 ENSEMBL UniProtKB {GO:0005813=GO_REF:0000019, GO:0005634=GO_REF:0000019} Q9BQI6 Ankyrin repeat domain-containing protein 32 protein 20130413 {GO:0005813=IEA, GO:0005634=IEA} centrosome, nucleus Human Ensembl:ENSMUSP00000118312 ANKRD34A HPA UniProtKB {GO:0005737=GO_REF:0000052} Q69YU3 Ankyrin repeat domain-containing protein 34A protein 20101115 {GO:0005737=IDA} cytoplasm Human ANKRD35 null null {} null null null null {} null null null ANKRD36C UniProtKB UniProtKB {GO:0008200=PMID:8608414} Q5JPF3 Ankyrin repeat domain-containing protein 36C protein 20090723 {GO:0008200=NAS} ion channel inhibitor activity Human ANKRD37 UniProtKB UniProtKB {GO:0005737=GO_REF:0000039, GO:0005634=GO_REF:0000039} Q7Z713 Ankyrin repeat domain-containing protein 37 protein 20130413 {GO:0005737=IEA, GO:0005634=IEA} cytoplasm, nucleus Human UniProtKB-SubCell:SL-0086 ANKRD39 BHF-UCL UniProtKB {GO:0003674=GO_REF:0000015, GO:0008150=GO_REF:0000015, GO:0005575=GO_REF:0000015} Q53RE8 Ankyrin repeat domain-containing protein 39 protein 20120523 {GO:0003674=ND, GO:0008150=ND, GO:0005575=ND} biological_process cellular_component molecular_function Human ANKRD40 BHF-UCL UniProtKB {GO:0008150=GO_REF:0000015, GO:0003674=GO_REF:0000015, GO:0005575=GO_REF:0000015} Q6AI12 Ankyrin repeat domain-containing protein 40 protein 20120523 {GO:0008150=ND, GO:0003674=ND, GO:0005575=ND} biological_process cellular_component molecular_function Human ANKRD42 ENSEMBL UniProtKB {GO:1900017=GO_REF:0000019, GO:0051092=GO_REF:0000019, GO:0051059=GO_REF:0000019, GO:0005634=GO_REF:0000019} Q8N9B4 Ankyrin repeat domain-containing protein 42 protein 20130413 {GO:1900017=IEA, GO:0051092=IEA, GO:0051059=IEA, GO:0005634=IEA} positive regulation of NF-kappaB transcription factor activity, positive regulation of cytokine production involved in inflammatory response nucleus NF-kappaB binding Human Ensembl:ENSMUSP00000113767 ANKRD44 null null {} null null null null {} null null null ANKRD45 BHF-UCL UniProtKB {GO:0008150=GO_REF:0000015, GO:0003674=GO_REF:0000015, GO:0005575=GO_REF:0000015} Q5TZF3 Ankyrin repeat domain-containing protein 45 protein 20120523 {GO:0008150=ND, GO:0003674=ND, GO:0005575=ND} biological_process cellular_component molecular_function Human ANKRD46 UniProtKB UniProtKB {GO:0016021=GO_REF:0000037} Q86W74 Ankyrin repeat domain-containing protein 46 protein 20130413 {GO:0016021=IEA} integral to membrane Human UniProtKB-KW:KW-0812 ANKRD50 null null {} null null null null {} null null null ANKRD52 null null {} null null null null {} null null null ANKRD53 null null {} null null null null {} null null null ANKRD55 null null {} null null null null {} null null null ANKRD6 ENSEMBL UniProtKB {GO:0005737=GO_REF:0000019, GO:2000096=GO_REF:0000019, GO:0005634=GO_REF:0000019, GO:0090090=GO_REF:0000019} Q9Y2G4 Ankyrin repeat domain-containing protein 6 protein 20130413 {GO:0005737=IEA, GO:2000096=IEA, GO:0005634=IEA, GO:0090090=IEA} negative regulation of canonical Wnt receptor signaling pathway, positive regulation of Wnt receptor signaling pathway, planar cell polarity pathway cytoplasm, nucleus Human Ensembl:ENSMUSP00000041300 ANKRD7 PINC UniProtKB {GO:0005634=GO_REF:0000019, GO:0008584=PMID:8812458} Q92527 Ankyrin repeat domain-containing protein 7 protein 20030904 {GO:0005634=IEA, GO:0008584=TAS} male gonad development nucleus Human ANKS1A HPA UniProtKB {GO:0016322=GO_REF:0000024, GO:0043005=GO_REF:0000024, GO:0005737=GO_REF:0000052, GO:0048013=GO_REF:0000024, GO:0046875=GO_REF:0000019, GO:0006929=GO_REF:0000024, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052} Q92625 Ankyrin repeat and SAM domain-containing protein 1A protein 20110516 {GO:0016322=ISS, GO:0043005=ISS, GO:0005737=IDA, GO:0048013=ISS, GO:0046875=IEA, GO:0006929=ISS, GO:0005730=IDA, GO:0005634=IDA} ephrin receptor signaling pathway, neuron remodeling, substrate-dependent cell migration cytoplasm, neuron projection, nucleolus, nucleus ephrin receptor binding Human ANKS1B UniProtKB UniProtKB {GO:0005737=GO_REF:0000039, GO:0015030=GO_REF:0000039, GO:0030054=GO_REF:0000037, GO:0046875=PMID:17875921, GO:0005886=GO_REF:0000037, GO:0045211=GO_REF:0000037, GO:0014069=GO_REF:0000039} Q7Z6G8 Ankyrin repeat and sterile alpha motif domain-containing protein 1B protein 20110826 {GO:0005737=IEA, GO:0015030=IEA, GO:0030054=IEA, GO:0046875=IPI, GO:0005886=IEA, GO:0045211=IEA, GO:0014069=IEA} Cajal body, cell junction, cytoplasm, plasma membrane, postsynaptic density, postsynaptic membrane ephrin receptor binding Human UniProtKB:O09127 ANKS3 null null {} null null null null {} null null null ANKS4B ENSEMBL UniProtKB {GO:0005886=GO_REF:0000019} Q8N8V4 Ankyrin repeat and SAM domain-containing protein 4B protein 20130413 {GO:0005886=IEA} plasma membrane Human Ensembl:ENSMUSP00000033201 ANKS6 ENSEMBL UniProtKB {GO:0005737=GO_REF:0000019, GO:0042803=GO_REF:0000019} Q68DC2 Ankyrin repeat and SAM domain-containing protein 6 protein 20130413 {GO:0005737=IEA, GO:0042803=IEA} cytoplasm protein homodimerization activity Human Ensembl:ENSRNOP00000056754 ANKZF1 IntAct UniProtKB {GO:0005515=PMID:22190034, GO:0008270=GO_REF:0000002} Q9H8Y5 Ankyrin repeat and zinc finger domain-containing protein 1 protein 20130415 {GO:0005515=IPI, GO:0008270=IEA} protein binding, zinc ion binding Human UniProtKB:Q9Q2G4 ANLN PINC UniProtKB {GO:0000910=PMID:10931866, GO:0005826=PMID:10931866, GO:0007067=GO_REF:0000037, GO:0000921=PMID:10931866, GO:0005543=GO_REF:0000002, GO:0007096=PMID:10931866, GO:0003779=PMID:10931866, GO:0005634=GO_REF:0000039, GO:0015629=PMID:10931866} Q9NQW6 Actin-binding protein anillin protein 20061106 {GO:0000910=IDA, GO:0005826=IDA, GO:0007067=IEA, GO:0000921=TAS, GO:0005543=IEA, GO:0007096=TAS, GO:0003779=IDA, GO:0005634=IEA, GO:0015629=IDA} cytokinesis, mitosis, regulation of exit from mitosis, septin ring assembly actin cytoskeleton, actomyosin contractile ring, nucleus actin binding, phospholipid binding Human ANO1 Reactome UniProtKB {GO:0005515=PMID:22178883, GO:0006821=GO_REF:0000024, GO:0005737=GO_REF:0000039, GO:0034220=Reactome:REACT_25300, GO:0005886=Reactome:REACT_160277, GO:0034707=GO_REF:0000037, GO:0005229=PMID:21984732, GO:0007275=GO_REF:0000037, GO:0016021=GO_REF:0000038, GO:0055085=Reactome:REACT_15518, GO:0005254=GO_REF:0000038} Q5XXA6 Anoctamin-1 protein 20130301 {GO:0005515=IPI, GO:0006821=ISS, GO:0005737=IEA, GO:0034220=TAS, GO:0005886=TAS, GO:0034707=IEA, GO:0005229=IDA, GO:0007275=IEA, GO:0016021=IEA, GO:0055085=TAS, GO:0005254=IEA} chloride transport, ion transmembrane transport, multicellular organismal development, transmembrane transport chloride channel complex, cytoplasm, integral to membrane, plasma membrane chloride channel activity, intracellular calcium activated chloride channel activity, protein binding Human ANO10 Reactome UniProtKB {GO:0005622=PMID:22075693, GO:0008219=GO_REF:0000037, GO:0034220=Reactome:REACT_25300, GO:0005886=Reactome:REACT_160277, GO:0034707=GO_REF:0000038, GO:0005229=PMID:21984732, GO:0016021=GO_REF:0000037, GO:0055085=Reactome:REACT_15518, GO:0005254=GO_REF:0000038} Q9NW15 Anoctamin-10 protein 20130301 {GO:0005622=IDA, GO:0008219=IEA, GO:0034220=TAS, GO:0005886=TAS, GO:0034707=IEA, GO:0005229=IDA, GO:0016021=IEA, GO:0055085=TAS, GO:0005254=IEA} cell death, ion transmembrane transport, transmembrane transport chloride channel complex, integral to membrane, intracellular, plasma membrane chloride channel activity, intracellular calcium activated chloride channel activity Human ANO2 HPA UniProtKB {GO:0034220=Reactome:REACT_25300, GO:0005886=GO_REF:0000052, GO:0034707=GO_REF:0000037, GO:0005730=GO_REF:0000052, GO:0005229=PMID:21984732, GO:0005634=GO_REF:0000052, GO:0016021=GO_REF:0000038, GO:0055085=Reactome:REACT_15518} Q9NQ90 Anoctamin-2 protein 20110516 {GO:0034220=TAS, GO:0005886=IDA, GO:0034707=IEA, GO:0005730=IDA, GO:0005229=IDA, GO:0005634=IDA, GO:0016021=IEA, GO:0055085=TAS} ion transmembrane transport, transmembrane transport chloride channel complex, integral to membrane, nucleolus, nucleus, plasma membrane intracellular calcium activated chloride channel activity Human ANO5 Reactome UniProtKB {GO:0005622=PMID:22075693, GO:0034220=Reactome:REACT_25300, GO:0005886=Reactome:REACT_160277, GO:0005789=GO_REF:0000039, GO:0005229=PMID:22075693, GO:0016021=GO_REF:0000037, GO:0055085=Reactome:REACT_15518} Q75V66 Anoctamin-5 protein 20130301 {GO:0005622=IDA, GO:0034220=TAS, GO:0005886=TAS, GO:0005789=IEA, GO:0005229=IDA, GO:0016021=IEA, GO:0055085=TAS} ion transmembrane transport, transmembrane transport endoplasmic reticulum membrane, integral to membrane, intracellular, plasma membrane intracellular calcium activated chloride channel activity Human ANO6 Reactome UniProtKB {GO:0017121=GO_REF:0000024, GO:0005244=GO_REF:0000024, GO:0005886=Reactome:REACT_160277, GO:0034707=GO_REF:0000037, GO:0002543=PMID:21107324, GO:0055085=Reactome:REACT_15518, GO:0005254=GO_REF:0000038, GO:0097045=PMID:21107324, GO:0005622=PMID:22075693, GO:0034220=Reactome:REACT_25300, GO:0007596=GO_REF:0000024, GO:0005229=PMID:21984732, GO:0016021=GO_REF:0000038, GO:0005227=GO_REF:0000024} Q4KMQ2 Anoctamin-6 protein 20130301 {GO:0017121=ISS, GO:0005244=ISS, GO:0005886=TAS, GO:0034707=IEA, GO:0002543=IMP, GO:0055085=TAS, GO:0005254=IEA, GO:0097045=IMP, GO:0005622=IDA, GO:0034220=TAS, GO:0007596=ISS, GO:0005229=IDA, GO:0016021=IEA, GO:0005227=ISS} activation of blood coagulation via clotting cascade, blood coagulation, ion transmembrane transport, phosphatidylserine exposure on blood platelet, phospholipid scrambling, transmembrane transport chloride channel complex, integral to membrane, intracellular, plasma membrane calcium activated cation channel activity, chloride channel activity, intracellular calcium activated chloride channel activity, voltage-gated ion channel activity Human ANO8 Reactome UniProtKB {GO:0005622=GO_REF:0000019, GO:0034220=Reactome:REACT_25300, GO:0005886=Reactome:REACT_160277, GO:0005229=PMID:21984732, GO:0016021=GO_REF:0000037, GO:0055085=Reactome:REACT_15518} Q9HCE9 Anoctamin-8 protein 20130301 {GO:0005622=IEA, GO:0034220=TAS, GO:0005886=TAS, GO:0005229=IDA, GO:0016021=IEA, GO:0055085=TAS} ion transmembrane transport, transmembrane transport integral to membrane, intracellular, plasma membrane intracellular calcium activated chloride channel activity Human ANP32A IntAct UniProtKB {GO:0005515=PMID:16169070, GO:0010467=Reactome:REACT_71, GO:0006355=GO_REF:0000037, GO:0048471=PMID:12524539, GO:0016070=Reactome:REACT_21257, GO:0005783=PMID:12524539, GO:0016071=Reactome:REACT_20605, GO:0005634=PMID:11729309, GO:0006351=GO_REF:0000037, GO:0006913=PMID:11729309, GO:0035556=PMID:8192856, GO:0005737=PMID:12524539, GO:0005654=Reactome:REACT_25286} P39687 Acidic leucine-rich nuclear phosphoprotein 32 family member A protein 20130415 {GO:0005515=IPI, GO:0010467=TAS, GO:0006355=IEA, GO:0048471=IDA, GO:0016070=TAS, GO:0005783=IDA, GO:0016071=TAS, GO:0005634=IDA, GO:0006351=IEA, GO:0006913=IDA, GO:0035556=TAS, GO:0005737=IDA, GO:0005654=TAS} RNA metabolic process, gene expression, intracellular signal transduction, mRNA metabolic process, nucleocytoplasmic transport, regulation of transcription, DNA-dependent, transcription, DNA-dependent cytoplasm, endoplasmic reticulum, nucleoplasm, nucleus, perinuclear region of cytoplasm protein binding Human UniProtKB:O15169 ANP32B UniProtKB UniProtKB {GO:0005737=GO_REF:0000039, GO:0005634=GO_REF:0000039} Q92688 Acidic leucine-rich nuclear phosphoprotein 32 family member B protein 20130413 {GO:0005737=IEA, GO:0005634=IEA} cytoplasm, nucleus Human UniProtKB-SubCell:SL-0086 ANP32D null null {} null null null null {} null null null ANP32E LIFEdb UniProtKB {GO:0016023=GO_REF:0000024, GO:0005634=GO_REF:0000054, GO:0019212=GO_REF:0000024} Q9BTT0 Acidic leucine-rich nuclear phosphoprotein 32 family member E protein 20100607 {GO:0016023=ISS, GO:0005634=IDA, GO:0019212=ISS} cytoplasmic membrane-bounded vesicle, nucleus phosphatase inhibitor activity Human ANPEP Reactome UniProtKB {GO:0005793=PMID:15308636, GO:0002003=Reactome:REACT_147707, GO:0001525=GO_REF:0000037, GO:0030154=GO_REF:0000037, GO:0005829=GO_REF:0000039, GO:0005887=PMID:2564851, GO:0004177=GO_REF:0000037, GO:0019048=GO_REF:0000037, GO:0006508=GO_REF:0000037, GO:0008270=GO_REF:0000002, GO:0004872=PMID:1350662, GO:0044267=Reactome:REACT_17015, GO:0009897=GO_REF:0000019, GO:0008237=GO_REF:0000037} P15144 Aminopeptidase N protein 20111129 {GO:0005793=IDA, GO:0002003=TAS, GO:0001525=IEA, GO:0030154=IEA, GO:0005829=IEA, GO:0005887=TAS, GO:0004177=IEA, GO:0019048=IEA, GO:0006508=IEA, GO:0008270=IEA, GO:0004872=TAS, GO:0044267=TAS, GO:0009897=IEA, GO:0008237=IEA} angiogenesis, angiotensin maturation, cell differentiation, cellular protein metabolic process, proteolysis, virus-host interaction cytosol, endoplasmic reticulum-Golgi intermediate compartment, external side of plasma membrane, integral to plasma membrane aminopeptidase activity, metallopeptidase activity, receptor activity, zinc ion binding Human ANTXR1 IntAct UniProtKB {GO:0005515=PMID:16564009, GO:0022414=GO_REF:0000019, GO:0051015=PMID:16762926, GO:0031532=PMID:16762926, GO:0031258=PMID:16762926, GO:0005518=PMID:16762926, GO:0031527=PMID:16762926, GO:0034446=PMID:16762926, GO:0004872=GO_REF:0000002, GO:0016021=GO_REF:0000037, GO:0046872=GO_REF:0000037, GO:0004888=PMID:16762926} Q9H6X2 Anthrax toxin receptor 1 protein 20130415 {GO:0005515=IPI, GO:0022414=IEA, GO:0051015=IDA, GO:0031532=IDA, GO:0031258=IDA, GO:0005518=IDA, GO:0031527=IDA, GO:0034446=IDA, GO:0004872=IEA, GO:0016021=IEA, GO:0046872=IEA, GO:0004888=IDA} actin cytoskeleton reorganization, reproductive process, substrate adhesion-dependent cell spreading filopodium membrane, integral to membrane, lamellipodium membrane actin filament binding, collagen binding, metal ion binding, protein binding, receptor activity, transmembrane signaling receptor activity Human UniProtKB:O75581 ANTXR2 IntAct UniProtKB {GO:0005515=PMID:15326297, GO:0022414=GO_REF:0000019, GO:0005886=GO_REF:0000039, GO:0005789=GO_REF:0000039, GO:0005576=GO_REF:0000039, GO:0004872=GO_REF:0000002, GO:0016021=GO_REF:0000019, GO:0046872=GO_REF:0000037} P58335 Anthrax toxin receptor 2 protein 20130415 {GO:0005515=IPI, GO:0022414=IEA, GO:0005886=IEA, GO:0005789=IEA, GO:0005576=IEA, GO:0004872=IEA, GO:0016021=IEA, GO:0046872=IEA} reproductive process endoplasmic reticulum membrane, extracellular region, integral to membrane, plasma membrane metal ion binding, protein binding, receptor activity Human UniProtKB:P13423 ANXA1 HPA UniProtKB {GO:0070301=GO_REF:0000019, GO:0046632=GO_REF:0000019, GO:0060206=GO_REF:0000019, GO:0005615=GO_REF:0000019, GO:0042803=GO_REF:0000019, GO:0042127=GO_REF:0000019, GO:0030674=PMID:10908733, GO:0032355=GO_REF:0000019, GO:0033031=GO_REF:0000019, GO:0031966=GO_REF:0000019, GO:0005509=GO_REF:0000002, GO:0031394=GO_REF:0000019, GO:0002674=GO_REF:0000019, GO:0042063=GO_REF:0000019, GO:0071385=GO_REF:0000019, GO:0043234=GO_REF:0000019, GO:0005929=GO_REF:0000039, GO:0007049=GO_REF:0000019, GO:0050709=GO_REF:0000019, GO:0030073=GO_REF:0000019, GO:0001780=GO_REF:0000019, GO:0010165=GO_REF:0000019, GO:0005886=GO_REF:0000052, GO:0043434=GO_REF:0000019, GO:0031340=PMID:2138016, GO:0006928=PMID:10882119, GO:0005634=GO_REF:0000019, GO:0001533=PMID:10908733, GO:0005544=GO_REF:0000002, GO:0016323=GO_REF:0000039, GO:0005737=GO_REF:0000052, GO:0005543=PMID:2967291, GO:0006954=PMID:10882119, GO:0070555=GO_REF:0000019, GO:0050482=GO_REF:0000019, GO:0043066=GO_REF:0000019, GO:0004859=GO_REF:0000002, GO:0042493=GO_REF:0000019, GO:0005102=PMID:10882119, GO:0005576=Reactome:REACT_22436, GO:0019834=GO_REF:0000019, GO:0042383=GO_REF:0000019, GO:0007165=PMID:16130169, GO:0018149=PMID:10908733, GO:0005198=PMID:10908733, GO:0030216=PMID:10908733, GO:0031018=GO_REF:0000019, GO:0007166=GO_REF:0000019, GO:0070365=GO_REF:0000019} Q5T3N1 Annexin A1 protein 20081203 {GO:0070301=IEA, GO:0046632=IEA, GO:0060206=IEA, GO:0005615=IEA, GO:0042803=IEA, GO:0042127=IEA, GO:0030674=IDA, GO:0032355=IEA, GO:0033031=IEA, GO:0031966=IEA, GO:0005509=IEA, GO:0031394=IEA, GO:0002674=IEA, GO:0042063=IEA, GO:0071385=IEA, GO:0043234=IEA, GO:0005929=IEA, GO:0007049=IEA, GO:0050709=IEA, GO:0030073=IEA, GO:0001780=IEA, GO:0010165=IEA, GO:0005886=IDA, GO:0043434=IEA, GO:0031340=IDA, GO:0006928=TAS, GO:0005634=IEA, GO:0001533=IDA, GO:0005544=IEA, GO:0016323=IEA, GO:0005737=IDA, GO:0005543=TAS, GO:0006954=TAS, GO:0070555=IEA, GO:0050482=IEA, GO:0043066=IEA, GO:0004859=IEA, GO:0042493=IEA, GO:0005102=TAS, GO:0005576=TAS, GO:0019834=IEA, GO:0042383=IEA, GO:0007165=TAS, GO:0018149=IDA, GO:0005198=IDA, GO:0030216=IDA, GO:0031018=IEA, GO:0007166=IEA, GO:0070365=IEA} alpha-beta T cell differentiation, arachidonic acid secretion, cell cycle, cell surface receptor signaling pathway, cellular component movement, cellular response to glucocorticoid stimulus, cellular response to hydrogen peroxide, endocrine pancreas development, estrous cycle phase, gliogenesis, hepatocyte differentiation, inflammatory response, insulin secretion, keratinocyte differentiation, negative regulation of acute inflammatory response, negative regulation of apoptotic process, negative regulation of protein secretion, neutrophil homeostasis, peptide cross-linking, positive regulation of neutrophil apoptotic process, positive regulation of prostaglandin biosynthetic process, positive regulation of vesicle fusion, regulation of cell proliferation, response to X-ray, response to drug, response to estradiol stimulus, response to interleukin-1, response to peptide hormone stimulus, signal transduction basolateral plasma membrane, cilium, cornified envelope, cytoplasm, extracellular region, extracellular space, mitochondrial membrane, nucleus, plasma membrane, protein complex, sarcolemma calcium ion binding, calcium-dependent phospholipid binding, phospholipase A2 inhibitor activity, phospholipase inhibitor activity, phospholipid binding, protein binding, bridging, protein homodimerization activity, receptor binding, structural molecule activity Human ANXA10 ENSEMBL UniProtKB {GO:0005739=GO_REF:0000019, GO:0005544=GO_REF:0000002, GO:0005509=GO_REF:0000002} Q9UJ72 Annexin A10 protein 20130413 {GO:0005739=IEA, GO:0005544=IEA, GO:0005509=IEA} mitochondrion calcium ion binding, calcium-dependent phospholipid binding Human Ensembl:ENSMUSP00000034052 ANXA11 ENSEMBL UniProtKB {GO:0006909=PMID:9188810, GO:0005515=PMID:9268363, GO:0042470=GO_REF:0000039, GO:0008429=GO_REF:0000019, GO:0005509=GO_REF:0000019, GO:0005819=PMID:12805373, GO:0030496=PMID:15197175, GO:0005635=PMID:12601007, GO:0007109=PMID:15197175, GO:0005544=GO_REF:0000019, GO:0051592=PMID:9188810, GO:0044548=PMID:19724273, GO:0005737=GO_REF:0000019, GO:0007049=GO_REF:0000037, GO:0005654=PMID:7508441, GO:0048306=PMID:11883939} Q5T0G9 Annexin A11 protein 20130413 {GO:0006909=IEP, GO:0005515=IPI, GO:0042470=IEA, GO:0008429=IEA, GO:0005509=IEA, GO:0005819=IDA, GO:0030496=IDA, GO:0005635=IDA, GO:0007109=IMP, GO:0005544=IEA, GO:0051592=IDA, GO:0044548=IPI, GO:0005737=IEA, GO:0007049=IEA, GO:0005654=IDA, GO:0048306=IPI} cell cycle, cytokinesis, completion of separation, phagocytosis, response to calcium ion cytoplasm, melanosome, midbody, nuclear envelope, nucleoplasm, spindle S100 protein binding, calcium ion binding, calcium-dependent phospholipid binding, calcium-dependent protein binding, phosphatidylethanolamine binding, protein binding Human Ensembl:ENSMUSP00000022416 ANXA13 HPA UniProtKB {GO:0005544=GO_REF:0000029, GO:0005886=GO_REF:0000052, GO:0005509=GO_REF:0000002, GO:0030154=PMID:1530946} P27216 Annexin A13 protein 20101115 {GO:0005544=NAS, GO:0005886=IDA, GO:0005509=IEA, GO:0030154=NAS} cell differentiation plasma membrane calcium ion binding, calcium-dependent phospholipid binding Human ANXA2 BHF-UCL UniProtKB {GO:0008092=GO_REF:0000002, GO:0005515=PMID:20706999, GO:0048471=GO_REF:0000019, GO:0005886=PMID:10809787, GO:0031340=PMID:2138016, GO:0005544=PMID:2138016, GO:0035749=GO_REF:0000019, GO:0030199=GO_REF:0000019, GO:0007589=GO_REF:0000019, GO:0043220=GO_REF:0000019, GO:0042470=GO_REF:0000039, GO:0017137=GO_REF:0000019, GO:0004859=GO_REF:0000002, GO:0005509=GO_REF:0000002, GO:0005546=GO_REF:0000019, GO:0051099=GO_REF:0000019, GO:0030496=PMID:15166316, GO:0001525=PMID:11866539, GO:0005604=GO_REF:0000039, GO:0031012=PMID:22261194, GO:0042383=GO_REF:0000019, GO:0043234=GO_REF:0000019, GO:0001501=PMID:7961821, GO:0071229=GO_REF:0000019, GO:0042730=GO_REF:0000019, GO:0019897=GO_REF:0000019, GO:0005769=GO_REF:0000019} P07355 Annexin A2 protein 20120228 {GO:0008092=IEA, GO:0005515=IPI, GO:0048471=IEA, GO:0005886=TAS, GO:0031340=IDA, GO:0005544=IDA, GO:0035749=IEA, GO:0030199=IEA, GO:0007589=IEA, GO:0043220=IEA, GO:0042470=IEA, GO:0017137=IEA, GO:0004859=IEA, GO:0005509=IEA, GO:0005546=IEA, GO:0051099=IEA, GO:0030496=IDA, GO:0001525=IEP, GO:0005604=IEA, GO:0031012=ISS, GO:0042383=IEA, GO:0043234=IEA, GO:0001501=TAS, GO:0071229=IEA, GO:0042730=IEA, GO:0019897=IEA, GO:0005769=IEA} angiogenesis, body fluid secretion, cellular response to acid, collagen fibril organization, fibrinolysis, positive regulation of binding, positive regulation of vesicle fusion, skeletal system development Schmidt-Lanterman incisure, basement membrane, early endosome, extracellular matrix, extrinsic to plasma membrane, melanosome, midbody, myelin sheath adaxonal region, perinuclear region of cytoplasm, plasma membrane, protein complex, sarcolemma Rab GTPase binding, calcium ion binding, calcium-dependent phospholipid binding, cytoskeletal protein binding, phosphatidylinositol-4,5-bisphosphate binding, phospholipase inhibitor activity, protein binding colocalizes_with Human UniProtKB:P19620 ANXA3 HPA UniProtKB {GO:0006909=PMID:9497492, GO:0004859=GO_REF:0000002, GO:0005886=PMID:7526843, GO:0043312=PMID:9550422, GO:0005509=GO_REF:0000002, GO:0042581=PMID:7526843, GO:0019834=GO_REF:0000037, GO:0045766=PMID:16236264, GO:0005544=PMID:2138632, GO:0010595=PMID:16236264, GO:0005737=GO_REF:0000052, GO:0051091=PMID:16236264, GO:0016020=PMID:17205602, GO:0030670=PMID:7526843, GO:0042742=PMID:9497492} P12429 Annexin A3 protein 20101115 {GO:0006909=IDA, GO:0004859=IEA, GO:0005886=IDA, GO:0043312=IDA, GO:0005509=IEA, GO:0042581=IDA, GO:0019834=IEA, GO:0045766=IDA, GO:0005544=IDA, GO:0010595=IDA, GO:0005737=IDA, GO:0051091=IDA, GO:0016020=IDA, GO:0030670=IDA, GO:0042742=IDA} defense response to bacterium, neutrophil degranulation, phagocytosis, positive regulation of angiogenesis, positive regulation of endothelial cell migration, positive regulation of sequence-specific DNA binding transcription factor activity cytoplasm, membrane, phagocytic vesicle membrane, plasma membrane, specific granule calcium ion binding, calcium-dependent phospholipid binding, phospholipase A2 inhibitor activity, phospholipase inhibitor activity Human ANXA4 UniProtKB UniProtKB {GO:0005544=GO_REF:0000038, GO:0007165=PMID:16130169, GO:0005737=PMID:16130169, GO:0043066=PMID:16130169, GO:0004859=PMID:2970257, GO:0050819=GO_REF:0000002, GO:0005509=GO_REF:0000002} Q6P452 Annexin protein 20130413 {GO:0005544=IEA, GO:0007165=TAS, GO:0005737=TAS, GO:0043066=TAS, GO:0004859=NAS, GO:0050819=IEA, GO:0005509=IEA} negative regulation of apoptotic process, negative regulation of coagulation, signal transduction cytoplasm calcium ion binding, calcium-dependent phospholipid binding, phospholipase inhibitor activity Human UniProtKB-KW:KW-0111 ANXA5 LIFEdb UniProtKB {GO:0043066=PMID:16130169, GO:0004859=PMID:2967495, GO:0010033=GO_REF:0000019, GO:0043499=GO_REF:0000019, GO:0005509=GO_REF:0000002, GO:0072563=GO_REF:0000019, GO:0005622=GO_REF:0000054, GO:0005544=PMID:2138016, GO:0007165=PMID:16130169, GO:0050819=GO_REF:0000002, GO:0005737=PMID:16130169, GO:0005543=PMID:2967291, GO:0007596=GO_REF:0000037, GO:0009897=GO_REF:0000019} P08758 Annexin A5 protein 20100607 {GO:0043066=TAS, GO:0004859=TAS, GO:0010033=IEA, GO:0043499=IEA, GO:0005509=IEA, GO:0072563=IEA, GO:0005622=IDA, GO:0005544=IDA, GO:0007165=TAS, GO:0050819=IEA, GO:0005737=TAS, GO:0005543=TAS, GO:0007596=IEA, GO:0009897=IEA} blood coagulation, negative regulation of apoptotic process, negative regulation of coagulation, response to organic substance, signal transduction cytoplasm, endothelial microparticle, external side of plasma membrane, intracellular calcium ion binding, calcium-dependent phospholipid binding, eukaryotic cell surface binding, phospholipase inhibitor activity, phospholipid binding Human ANXA6 UniProtKB UniProtKB {GO:0005515=PMID:15576473, GO:0005544=PMID:2138016, GO:0042470=GO_REF:0000039, GO:0048471=GO_REF:0000019, GO:0006937=GO_REF:0000019, GO:0005509=GO_REF:0000002, GO:0006816=GO_REF:0000019} P08133 Annexin A6 protein 20100208 {GO:0005515=IPI, GO:0005544=IDA, GO:0042470=IEA, GO:0048471=IEA, GO:0006937=IEA, GO:0005509=IEA, GO:0006816=IEA} calcium ion transport, regulation of muscle contraction melanosome, perinuclear region of cytoplasm calcium ion binding, calcium-dependent phospholipid binding, protein binding Human ANXA7 BHF-UCL UniProtKB {GO:0005515=PMID:9268363, GO:0009651=GO_REF:0000019, GO:0005886=GO_REF:0000019, GO:0008283=GO_REF:0000019, GO:0008360=GO_REF:0000019, GO:0005509=GO_REF:0000002, GO:0006874=GO_REF:0000019, GO:0009992=GO_REF:0000019, GO:0005634=PMID:10672515, GO:0005635=GO_REF:0000019, GO:0031982=GO_REF:0000019, GO:0005829=GO_REF:0000019, GO:0005544=GO_REF:0000037, GO:0007599=GO_REF:0000019, GO:0042584=PMID:9268363, GO:0035176=PMID:21531385, GO:0005789=PMID:10672515, GO:0048306=PMID:12445460} P20073 Annexin A7 protein 20130128 {GO:0005515=IPI, GO:0009651=IEA, GO:0005886=IEA, GO:0008283=IEA, GO:0008360=IEA, GO:0005509=IEA, GO:0006874=IEA, GO:0009992=IEA, GO:0005634=IDA, GO:0005635=IEA, GO:0031982=IEA, GO:0005829=IEA, GO:0005544=IEA, GO:0007599=IEA, GO:0042584=IDA, GO:0035176=IEP, GO:0005789=IDA, GO:0048306=IPI} cell proliferation, cellular calcium ion homeostasis, cellular water homeostasis, hemostasis, regulation of cell shape, response to salt stress, social behavior chromaffin granule membrane, cytosol, endoplasmic reticulum membrane, nuclear envelope, nucleus, plasma membrane, vesicle calcium ion binding, calcium-dependent phospholipid binding, calcium-dependent protein binding, protein binding colocalizes_with Human ANXA8 InterPro UniProtKB {GO:0005544=GO_REF:0000002, GO:0007596=GO_REF:0000037, GO:0005509=GO_REF:0000002} Q5VTM3 Annexin A8 protein 20130413 {GO:0005544=IEA, GO:0007596=IEA, GO:0005509=IEA} blood coagulation calcium ion binding, calcium-dependent phospholipid binding Human InterPro:IPR001464|InterPro:IPR009115|InterPro:IPR018252|InterPro:IPR018502 ANXA8L1 UniProtKB UniProtKB {GO:0005544=GO_REF:0000037, GO:0005509=GO_REF:0000002} Q5T2P8 Annexin A8-like protein 1 protein 20130413 {GO:0005544=IEA, GO:0005509=IEA} calcium ion binding, calcium-dependent phospholipid binding Human UniProtKB-KW:KW-0111 ANXA8L2 UniProtKB UniProtKB {GO:0005544=GO_REF:0000037, GO:0005509=GO_REF:0000002} Q5VT79 Annexin A8-like protein 2 protein 20130413 {GO:0005544=IEA, GO:0005509=IEA} calcium ion binding, calcium-dependent phospholipid binding Human UniProtKB-KW:KW-0111 ANXA9 UniProtKB UniProtKB {GO:0005544=GO_REF:0000002, GO:0016337=PMID:10899159, GO:0005543=PMID:10899159, GO:0009986=PMID:10899159, GO:0015464=PMID:10899159, GO:0005509=GO_REF:0000002, GO:0001786=PMID:12832069, GO:0042803=PMID:10899159, GO:0005829=PMID:12832069} O76027 Annexin A9 protein 20050704 {GO:0005544=IEA, GO:0016337=IDA, GO:0005543=IDA, GO:0009986=IDA, GO:0015464=IDA, GO:0005509=IEA, GO:0001786=IDA, GO:0042803=TAS, GO:0005829=IDA} cell-cell adhesion cell surface, cytosol acetylcholine receptor activity, calcium ion binding, calcium-dependent phospholipid binding, phosphatidylserine binding, phospholipid binding, protein homodimerization activity Human AOC3 UniProtKB UniProtKB {GO:0005261=PMID:19764817, GO:0048038=PMID:9653080, GO:0009986=PMID:9653080, GO:0005886=PMID:9653080, GO:0005507=PMID:19764817, GO:0005509=PMID:19764817, GO:0052596=GO_REF:0000003, GO:0052595=GO_REF:0000003, GO:0052594=GO_REF:0000003, GO:0052593=GO_REF:0000003, GO:0042803=PMID:9653080, GO:0008131=PMID:19764817, GO:0006954=PMID:9653080, GO:0009308=PMID:9653080, GO:0016021=PMID:9653080, GO:0007155=PMID:9653080, GO:0046677=PMID:19764817} Q16853 Membrane primary amine oxidase protein 20111111 {GO:0005261=IDA, GO:0048038=IDA, GO:0009986=IDA, GO:0005886=IDA, GO:0005507=IDA, GO:0005509=IDA, GO:0052596=IEA, GO:0052595=IEA, GO:0052594=IEA, GO:0052593=IEA, GO:0042803=TAS, GO:0008131=IDA, GO:0006954=TAS, GO:0009308=IDA, GO:0016021=IDA, GO:0007155=IDA, GO:0046677=IDA} amine metabolic process, cell adhesion, inflammatory response, response to antibiotic cell surface, integral to membrane, plasma membrane aliphatic-amine oxidase activity, aminoacetone:oxygen oxidoreductase(deaminating) activity, calcium ion binding, cation channel activity, copper ion binding, phenethylamine:oxygen oxidoreductase (deaminating) activity, primary amine oxidase activity, protein homodimerization activity, quinone binding, tryptamine:oxygen oxidoreductase (deaminating) activity Human AOX1 HPA UniProtKB {GO:0008762=GO_REF:0000002, GO:0005506=GO_REF:0000002, GO:0051537=GO_REF:0000037, GO:0004854=PMID:8248161, GO:0050660=GO_REF:0000002, GO:0072593=PMID:7570184, GO:0009055=GO_REF:0000002, GO:0046872=GO_REF:0000002, GO:0004031=GO_REF:0000003, GO:0043546=GO_REF:0000002, GO:0005737=GO_REF:0000052, GO:0051287=GO_REF:0000002, GO:0006954=PMID:8248161, GO:0016491=GO_REF:0000002} Q06278 Aldehyde oxidase protein 20111111 {GO:0008762=IEA, GO:0005506=IEA, GO:0051537=IEA, GO:0004854=TAS, GO:0050660=IEA, GO:0072593=TAS, GO:0009055=IEA, GO:0046872=IEA, GO:0004031=IEA, GO:0043546=IEA, GO:0005737=IDA, GO:0051287=IEA, GO:0006954=TAS, GO:0016491=IEA} inflammatory response, reactive oxygen species metabolic process cytoplasm 2 iron, 2 sulfur cluster binding, NAD binding, UDP-N-acetylmuramate dehydrogenase activity, aldehyde oxidase activity, electron carrier activity, flavin adenine dinucleotide binding, iron ion binding, metal ion binding, molybdopterin cofactor binding, oxidoreductase activity, xanthine dehydrogenase activity Human AP1AR HPA UniProtKB {GO:0030133=GO_REF:0000054, GO:0005737=GO_REF:0000052, GO:0005794=GO_REF:0000052, GO:0005770=GO_REF:0000039, GO:1900025=PMID:22689987, GO:0034315=GO_REF:0000019, GO:0005730=GO_REF:0000052, GO:2000146=GO_REF:0000019, GO:0034613=GO_REF:0000019, GO:0015031=GO_REF:0000037, GO:0005769=GO_REF:0000039} Q63HQ0 AP-1 complex-associated regulatory protein protein 20110516 {GO:0030133=IDA, GO:0005737=IDA, GO:0005794=IDA, GO:0005770=IEA, GO:1900025=IMP, GO:0034315=IEA, GO:0005730=IDA, GO:2000146=IEA, GO:0034613=IEA, GO:0015031=IEA, GO:0005769=IEA} cellular protein localization, negative regulation of cell motility, negative regulation of substrate adhesion-dependent cell spreading, protein transport, regulation of Arp2/3 complex-mediated actin nucleation Golgi apparatus, cytoplasm, early endosome, late endosome, nucleolus, transport vesicle Human AP1B1 Reactome UniProtKB {GO:0005515=PMID:9733768, GO:0005215=PMID:7987321, GO:0030131=GO_REF:0000002, GO:0006892=Reactome:REACT_11235, GO:0005765=Reactome:REACT_19206, GO:0032588=Reactome:REACT_121003, GO:0006886=GO_REF:0000002, GO:0030117=GO_REF:0000002, GO:0050690=Reactome:REACT_11149, GO:0006897=GO_REF:0000037, GO:0005829=Reactome:REACT_121003, GO:0019886=Reactome:REACT_121399, GO:0030665=GO_REF:0000039, GO:0000139=Reactome:REACT_19391, GO:0008565=GO_REF:0000002, GO:0016032=Reactome:REACT_6185, GO:0016192=GO_REF:0000002, GO:0030659=Reactome:REACT_19255, GO:0016044=Reactome:REACT_11123} Q10567 AP-1 complex subunit beta-1 protein 20130213 {GO:0005515=IPI, GO:0005215=TAS, GO:0030131=IEA, GO:0006892=TAS, GO:0005765=TAS, GO:0032588=TAS, GO:0006886=IEA, GO:0030117=IEA, GO:0050690=TAS, GO:0006897=IEA, GO:0005829=TAS, GO:0019886=TAS, GO:0030665=IEA, GO:0000139=TAS, GO:0008565=IEA, GO:0016032=TAS, GO:0016192=IEA, GO:0030659=TAS, GO:0016044=TAS} antigen processing and presentation of exogenous peptide antigen via MHC class II, cellular membrane organization, endocytosis, intracellular protein transport, post-Golgi vesicle-mediated transport, regulation of defense response to virus by virus, vesicle-mediated transport, viral reproduction Golgi membrane, clathrin adaptor complex, clathrin-coated vesicle membrane, cytoplasmic vesicle membrane, cytosol, lysosomal membrane, membrane coat, trans-Golgi network membrane protein binding, protein transporter activity, transporter activity Human AP1G1 BHF-UCL UniProtKB {GO:0005515=PMID:12505986, GO:0005802=GO_REF:0000019, GO:0005215=PMID:9733768, GO:0048471=GO_REF:0000019, GO:0030131=GO_REF:0000002, GO:0030136=PMID:12536145, GO:0030119=PMID:9653655, GO:0005765=Reactome:REACT_19206, GO:0006886=GO_REF:0000002, GO:0030117=GO_REF:0000002, GO:0005829=Reactome:REACT_121003, GO:0019886=Reactome:REACT_121399, GO:0005737=PMID:9733768, GO:0016032=Reactome:REACT_6185, GO:0016192=GO_REF:0000002, GO:0030659=Reactome:REACT_19255, GO:0005794=PMID:9733768, GO:0006892=Reactome:REACT_11235, GO:0032588=Reactome:REACT_121003, GO:0050690=Reactome:REACT_11149, GO:0006897=GO_REF:0000037, GO:0030665=GO_REF:0000024, GO:0000139=Reactome:REACT_19391, GO:0008565=GO_REF:0000002, GO:0019894=PMID:19841138, GO:0055037=PMID:19841138, GO:0016044=Reactome:REACT_11123} O43747 AP-1 complex subunit gamma-1 protein 20110308 {GO:0005515=IPI, GO:0005802=IEA, GO:0005215=TAS, GO:0048471=IEA, GO:0030131=IEA, GO:0030136=IDA, GO:0030119=TAS, GO:0005765=TAS, GO:0006886=IEA, GO:0030117=IEA, GO:0005829=TAS, GO:0019886=TAS, GO:0005737=TAS, GO:0016032=TAS, GO:0016192=IEA, GO:0030659=TAS, GO:0005794=IDA, GO:0006892=TAS, GO:0032588=TAS, GO:0050690=TAS, GO:0006897=IEA, GO:0030665=ISS, GO:0000139=TAS, GO:0008565=IEA, GO:0019894=IPI, GO:0055037=IDA, GO:0016044=TAS} antigen processing and presentation of exogenous peptide antigen via MHC class II, cellular membrane organization, endocytosis, intracellular protein transport, post-Golgi vesicle-mediated transport, regulation of defense response to virus by virus, vesicle-mediated transport, viral reproduction AP-type membrane coat adaptor complex, Golgi apparatus, Golgi membrane, clathrin adaptor complex, clathrin-coated vesicle, clathrin-coated vesicle membrane, cytoplasm, cytoplasmic vesicle membrane, cytosol, lysosomal membrane, membrane coat, perinuclear region of cytoplasm, recycling endosome, trans-Golgi network, trans-Golgi network membrane kinesin binding, protein binding, protein transporter activity, transporter activity Human UniProtKB:Q8R525 AP1G2 UniProtKB UniProtKB {GO:0030133=GO_REF:0000024, GO:0005515=PMID:12505986, GO:0030131=GO_REF:0000002, GO:0005794=PMID:9762922, GO:0030121=PMID:9733768, GO:0005798=GO_REF:0000024, GO:0006886=GO_REF:0000002, GO:0030117=GO_REF:0000002, GO:0016020=GO_REF:0000024, GO:0019048=GO_REF:0000037, GO:0008565=GO_REF:0000002, GO:0016192=GO_REF:0000002, GO:0010008=GO_REF:0000039} Q86V28 AP1G2 protein protein 20041006 {GO:0030133=ISS, GO:0005515=IPI, GO:0030131=IEA, GO:0005794=TAS, GO:0030121=TAS, GO:0005798=ISS, GO:0006886=IEA, GO:0030117=IEA, GO:0016020=ISS, GO:0019048=IEA, GO:0008565=IEA, GO:0016192=IEA, GO:0010008=IEA} intracellular protein transport, vesicle-mediated transport, virus-host interaction AP-1 adaptor complex, Golgi apparatus, Golgi-associated vesicle, clathrin adaptor complex, endosome membrane, membrane, membrane coat, transport vesicle protein binding, protein transporter activity Human UniProtKB:O75843 AP1M1 IntAct UniProtKB {GO:0005515=PMID:19060904, GO:0030131=GO_REF:0000002, GO:0032438=PMID:19841138, GO:0006892=Reactome:REACT_11235, GO:0005765=Reactome:REACT_19206, GO:0032588=Reactome:REACT_121003, GO:0006886=GO_REF:0000002, GO:0050690=Reactome:REACT_11149, GO:0005829=Reactome:REACT_121003, GO:0019886=Reactome:REACT_121399, GO:0030665=GO_REF:0000039, GO:0000139=Reactome:REACT_19391, GO:0019048=GO_REF:0000037, GO:0006810=GO_REF:0000002, GO:0035646=PMID:19841138, GO:0016032=Reactome:REACT_6185, GO:0016192=GO_REF:0000002, GO:0030659=Reactome:REACT_19255, GO:0016044=Reactome:REACT_11123} Q9BXS5 AP-1 complex subunit mu-1 protein 20130415 {GO:0005515=IPI, GO:0030131=IEA, GO:0032438=IMP, GO:0006892=TAS, GO:0005765=TAS, GO:0032588=TAS, GO:0006886=IEA, GO:0050690=TAS, GO:0005829=TAS, GO:0019886=TAS, GO:0030665=IEA, GO:0000139=TAS, GO:0019048=IEA, GO:0006810=IEA, GO:0035646=IMP, GO:0016032=TAS, GO:0016192=IEA, GO:0030659=TAS, GO:0016044=TAS} antigen processing and presentation of exogenous peptide antigen via MHC class II, cellular membrane organization, endosome to melanosome transport, intracellular protein transport, melanosome organization, post-Golgi vesicle-mediated transport, regulation of defense response to virus by virus, transport, vesicle-mediated transport, viral reproduction, virus-host interaction Golgi membrane, clathrin adaptor complex, clathrin-coated vesicle membrane, cytoplasmic vesicle membrane, cytosol, lysosomal membrane, trans-Golgi network membrane protein binding Human UniProtKB:Q14872 AP1M2 Reactome UniProtKB {GO:0030131=GO_REF:0000002, GO:0006892=Reactome:REACT_11235, GO:0006605=PMID:10338135, GO:0005765=Reactome:REACT_19206, GO:0032588=Reactome:REACT_121003, GO:0006886=GO_REF:0000002, GO:0006903=PMID:10338135, GO:0050690=Reactome:REACT_11149, GO:0005829=Reactome:REACT_121003, GO:0030665=GO_REF:0000039, GO:0019886=Reactome:REACT_121399, GO:0000139=Reactome:REACT_19391, GO:0016032=Reactome:REACT_6185, GO:0016192=GO_REF:0000002, GO:0030659=Reactome:REACT_19255, GO:0016044=Reactome:REACT_11123} Q9Y6Q5 AP-1 complex subunit mu-2 protein 20070808 {GO:0030131=IEA, GO:0006892=TAS, GO:0006605=TAS, GO:0005765=TAS, GO:0032588=TAS, GO:0006886=IEA, GO:0006903=TAS, GO:0050690=TAS, GO:0005829=TAS, GO:0030665=IEA, GO:0019886=TAS, GO:0000139=TAS, GO:0016032=TAS, GO:0016192=IEA, GO:0030659=TAS, GO:0016044=TAS} antigen processing and presentation of exogenous peptide antigen via MHC class II, cellular membrane organization, intracellular protein transport, post-Golgi vesicle-mediated transport, protein targeting, regulation of defense response to virus by virus, vesicle targeting, vesicle-mediated transport, viral reproduction Golgi membrane, clathrin adaptor complex, clathrin-coated vesicle membrane, cytoplasmic vesicle membrane, cytosol, lysosomal membrane, trans-Golgi network membrane Human AP1S1 Reactome UniProtKB {GO:0030121=PMID:9733768, GO:0006892=Reactome:REACT_11235, GO:0009615=PMID:16548883, GO:0005765=Reactome:REACT_19206, GO:0032588=Reactome:REACT_121003, GO:0006886=GO_REF:0000002, GO:0030117=GO_REF:0000002, GO:0006898=PMID:9733768, GO:0050690=Reactome:REACT_11149, GO:0005829=Reactome:REACT_121003, GO:0019886=Reactome:REACT_121399, GO:0005905=GO_REF:0000039, GO:0000139=Reactome:REACT_19391, GO:0008565=GO_REF:0000002, GO:0016032=Reactome:REACT_6185, GO:0030130=GO_REF:0000029, GO:0016192=GO_REF:0000002, GO:0030659=Reactome:REACT_19255, GO:0016044=Reactome:REACT_11123} P61966 AP-1 complex subunit sigma-1A protein 20070808 {GO:0030121=TAS, GO:0006892=TAS, GO:0009615=IEP, GO:0005765=TAS, GO:0032588=TAS, GO:0006886=IEA, GO:0030117=IEA, GO:0006898=TAS, GO:0050690=TAS, GO:0005829=TAS, GO:0019886=TAS, GO:0005905=IEA, GO:0000139=TAS, GO:0008565=IEA, GO:0016032=TAS, GO:0030130=NAS, GO:0016192=IEA, GO:0030659=TAS, GO:0016044=TAS} antigen processing and presentation of exogenous peptide antigen via MHC class II, cellular membrane organization, intracellular protein transport, post-Golgi vesicle-mediated transport, receptor-mediated endocytosis, regulation of defense response to virus by virus, response to virus, vesicle-mediated transport, viral reproduction AP-1 adaptor complex, Golgi membrane, clathrin coat of trans-Golgi network vesicle, coated pit, cytoplasmic vesicle membrane, cytosol, lysosomal membrane, membrane coat, trans-Golgi network membrane protein transporter activity Human AP1S2 Reactome UniProtKB {GO:0006892=Reactome:REACT_11235, GO:0030119=PMID:9733768, GO:0005765=Reactome:REACT_19206, GO:0032588=Reactome:REACT_121003, GO:0006886=GO_REF:0000002, GO:0030117=GO_REF:0000002, GO:0050690=Reactome:REACT_11149, GO:0006897=GO_REF:0000037, GO:0005829=Reactome:REACT_121003, GO:0019886=Reactome:REACT_121399, GO:0005905=GO_REF:0000039, GO:0000139=Reactome:REACT_19391, GO:0008565=GO_REF:0000002, GO:0016032=Reactome:REACT_6185, GO:0016192=GO_REF:0000002, GO:0030659=Reactome:REACT_19255, GO:0016044=Reactome:REACT_11123} P56377 AP-1 complex subunit sigma-2 protein 20070808 {GO:0006892=TAS, GO:0030119=TAS, GO:0005765=TAS, GO:0032588=TAS, GO:0006886=IEA, GO:0030117=IEA, GO:0050690=TAS, GO:0006897=IEA, GO:0005829=TAS, GO:0019886=TAS, GO:0005905=IEA, GO:0000139=TAS, GO:0008565=IEA, GO:0016032=TAS, GO:0016192=IEA, GO:0030659=TAS, GO:0016044=TAS} antigen processing and presentation of exogenous peptide antigen via MHC class II, cellular membrane organization, endocytosis, intracellular protein transport, post-Golgi vesicle-mediated transport, regulation of defense response to virus by virus, vesicle-mediated transport, viral reproduction AP-type membrane coat adaptor complex, Golgi membrane, coated pit, cytoplasmic vesicle membrane, cytosol, lysosomal membrane, membrane coat, trans-Golgi network membrane protein transporter activity Human AP1S3 Reactome UniProtKB {GO:0006892=Reactome:REACT_11235, GO:0005765=Reactome:REACT_19206, GO:0006886=GO_REF:0000002, GO:0032588=Reactome:REACT_120943, GO:0030117=GO_REF:0000002, GO:0006897=GO_REF:0000037, GO:0050690=Reactome:REACT_11149, GO:0005829=Reactome:REACT_121003, GO:0019886=Reactome:REACT_121399, GO:0005905=GO_REF:0000039, GO:0000139=Reactome:REACT_19391, GO:0008565=GO_REF:0000002, GO:0016032=Reactome:REACT_6185, GO:0016192=GO_REF:0000002, GO:0030659=Reactome:REACT_19255, GO:0016044=Reactome:REACT_11123} Q96PC3 AP-1 complex subunit sigma-3 protein 20130213 {GO:0006892=TAS, GO:0005765=TAS, GO:0006886=IEA, GO:0032588=TAS, GO:0030117=IEA, GO:0006897=IEA, GO:0050690=TAS, GO:0005829=TAS, GO:0019886=TAS, GO:0005905=IEA, GO:0000139=TAS, GO:0008565=IEA, GO:0016032=TAS, GO:0016192=IEA, GO:0030659=TAS, GO:0016044=TAS} antigen processing and presentation of exogenous peptide antigen via MHC class II, cellular membrane organization, endocytosis, intracellular protein transport, post-Golgi vesicle-mediated transport, regulation of defense response to virus by virus, vesicle-mediated transport, viral reproduction Golgi membrane, coated pit, cytoplasmic vesicle membrane, cytosol, lysosomal membrane, membrane coat, trans-Golgi network membrane protein transporter activity Human AP2A1 Reactome UniProtKB {GO:0005515=PMID:19116314, GO:0048011=Reactome:REACT_11061, GO:0005886=Reactome:REACT_121177, GO:0030122=PMID:12036598, GO:0042059=Reactome:REACT_12484, GO:0007268=Reactome:REACT_13685, GO:0008022=GO_REF:0000019, GO:0006895=PMID:12036598, GO:0006886=PMID:12036598, GO:0050690=Reactome:REACT_11200, GO:0006897=PMID:12036598, GO:0005829=Reactome:REACT_11177, GO:0030666=Reactome:REACT_18330, GO:0019886=Reactome:REACT_121399, GO:0016323=GO_REF:0000019, GO:0016324=GO_REF:0000019, GO:0007173=Reactome:REACT_9417, GO:0007411=Reactome:REACT_18266, GO:0008565=GO_REF:0000002, GO:0016032=Reactome:REACT_6185, GO:0030130=PMID:12036598} O95782 AP-2 complex subunit alpha-1 protein 20070808 {GO:0005515=IPI, GO:0048011=TAS, GO:0005886=TAS, GO:0030122=NAS, GO:0042059=TAS, GO:0007268=TAS, GO:0008022=IEA, GO:0006895=NAS, GO:0006886=NAS, GO:0050690=TAS, GO:0006897=NAS, GO:0005829=TAS, GO:0030666=TAS, GO:0019886=TAS, GO:0016323=IEA, GO:0016324=IEA, GO:0007173=TAS, GO:0007411=TAS, GO:0008565=IEA, GO:0016032=TAS, GO:0030130=NAS} Golgi to endosome transport, antigen processing and presentation of exogenous peptide antigen via MHC class II, axon guidance, endocytosis, epidermal growth factor receptor signaling pathway, intracellular protein transport, negative regulation of epidermal growth factor receptor signaling pathway, neurotrophin TRK receptor signaling pathway, regulation of defense response to virus by virus, synaptic transmission, viral reproduction AP-2 adaptor complex, apical plasma membrane, basolateral plasma membrane, clathrin coat of trans-Golgi network vesicle, cytosol, endocytic vesicle membrane, plasma membrane protein C-terminus binding, protein binding, protein transporter activity Human AP2A2 IntAct UniProtKB {GO:0005515=PMID:22323290, GO:0048011=Reactome:REACT_11061, GO:0030131=GO_REF:0000002, GO:0005886=Reactome:REACT_121177, GO:0030122=GO_REF:0000029, GO:0042059=Reactome:REACT_12484, GO:0007268=Reactome:REACT_13685, GO:0006886=GO_REF:0000029, GO:0030117=GO_REF:0000002, GO:0050690=Reactome:REACT_11200, GO:0006897=GO_REF:0000037, GO:0008289=GO_REF:0000037, GO:0005829=Reactome:REACT_11177, GO:0030666=Reactome:REACT_18330, GO:0019886=Reactome:REACT_121399, GO:0003674=GO_REF:0000015, GO:0007173=Reactome:REACT_9417, GO:0007411=Reactome:REACT_18266, GO:0008565=GO_REF:0000002, GO:0016032=Reactome:REACT_6185, GO:0016192=GO_REF:0000002} O94973 AP-2 complex subunit alpha-2 protein 20130415 {GO:0005515=IPI, GO:0048011=TAS, GO:0030131=IEA, GO:0005886=TAS, GO:0030122=NAS, GO:0042059=TAS, GO:0007268=TAS, GO:0006886=NAS, GO:0030117=IEA, GO:0050690=TAS, GO:0006897=IEA, GO:0008289=IEA, GO:0005829=TAS, GO:0030666=TAS, GO:0019886=TAS, GO:0003674=ND, GO:0007173=TAS, GO:0007411=TAS, GO:0008565=IEA, GO:0016032=TAS, GO:0016192=IEA} antigen processing and presentation of exogenous peptide antigen via MHC class II, axon guidance, endocytosis, epidermal growth factor receptor signaling pathway, intracellular protein transport, negative regulation of epidermal growth factor receptor signaling pathway, neurotrophin TRK receptor signaling pathway, regulation of defense response to virus by virus, synaptic transmission, vesicle-mediated transport, viral reproduction AP-2 adaptor complex, clathrin adaptor complex, cytosol, endocytic vesicle membrane, membrane coat, plasma membrane lipid binding, molecular_function, protein binding, protein transporter activity Human UniProtKB:P98078 AP2B1 InterPro UniProtKB {GO:0005515=PMID:12221107, GO:0005802=GO_REF:0000019, GO:0048011=Reactome:REACT_11061, GO:0030131=GO_REF:0000002, GO:0005886=Reactome:REACT_120835, GO:0042059=Reactome:REACT_12484, GO:0007268=Reactome:REACT_13685, GO:0006886=GO_REF:0000002, GO:0032403=GO_REF:0000019, GO:0030117=GO_REF:0000002, GO:0050690=Reactome:REACT_11200, GO:0005829=Reactome:REACT_11177, GO:0030666=Reactome:REACT_18330, GO:0019886=Reactome:REACT_121399, GO:0005905=GO_REF:0000039, GO:0007173=Reactome:REACT_9417, GO:0007411=Reactome:REACT_18266, GO:0030276=PMID:19509056, GO:0008565=GO_REF:0000002, GO:0016032=Reactome:REACT_6185, GO:0016192=GO_REF:0000002, GO:0030669=Reactome:REACT_121177, GO:0048268=GO_REF:0000019} Q7Z451 AP-2 complex subunit beta protein 20130413 {GO:0005515=IPI, GO:0005802=IEA, GO:0048011=TAS, GO:0030131=IEA, GO:0005886=TAS, GO:0042059=TAS, GO:0007268=TAS, GO:0006886=IEA, GO:0032403=IEA, GO:0030117=IEA, GO:0050690=TAS, GO:0005829=TAS, GO:0030666=TAS, GO:0019886=TAS, GO:0005905=IEA, GO:0007173=TAS, GO:0007411=TAS, GO:0030276=IPI, GO:0008565=IEA, GO:0016032=TAS, GO:0016192=IEA, GO:0030669=TAS, GO:0048268=IEA} antigen processing and presentation of exogenous peptide antigen via MHC class II, axon guidance, clathrin coat assembly, epidermal growth factor receptor signaling pathway, intracellular protein transport, negative regulation of epidermal growth factor receptor signaling pathway, neurotrophin TRK receptor signaling pathway, regulation of defense response to virus by virus, synaptic transmission, vesicle-mediated transport, viral reproduction clathrin adaptor complex, clathrin-coated endocytic vesicle membrane, coated pit, cytosol, endocytic vesicle membrane, membrane coat, plasma membrane, trans-Golgi network clathrin binding, protein binding, protein complex binding, protein transporter activity Human InterPro:IPR008152|InterPro:IPR013037|InterPro:IPR015151 AP2M1 Reactome UniProtKB {GO:0005515=PMID:19419997, GO:0005215=PMID:8595912, GO:0048011=Reactome:REACT_11061, GO:0030131=GO_REF:0000002, GO:0030132=GO_REF:0000002, GO:0005886=Reactome:REACT_120835, GO:0042059=Reactome:REACT_12484, GO:0007268=Reactome:REACT_13685, GO:0005765=Reactome:REACT_10083, GO:0006886=GO_REF:0000002, GO:0050690=Reactome:REACT_11200, GO:0008289=GO_REF:0000037, GO:0005829=Reactome:REACT_11177, GO:0030666=Reactome:REACT_18330, GO:0005739=GO_REF:0000019, GO:0019886=Reactome:REACT_121399, GO:0007173=Reactome:REACT_9417, GO:0007411=Reactome:REACT_18266, GO:0016032=Reactome:REACT_6185, GO:0016192=GO_REF:0000002, GO:0030669=Reactome:REACT_121177, GO:0016044=Reactome:REACT_11123} Q96CW1 AP-2 complex subunit mu protein 20130213 {GO:0005515=IPI, GO:0005215=TAS, GO:0048011=TAS, GO:0030131=IEA, GO:0030132=IEA, GO:0005886=TAS, GO:0042059=TAS, GO:0007268=TAS, GO:0005765=TAS, GO:0006886=IEA, GO:0050690=TAS, GO:0008289=IEA, GO:0005829=TAS, GO:0030666=TAS, GO:0005739=IEA, GO:0019886=TAS, GO:0007173=TAS, GO:0007411=TAS, GO:0016032=TAS, GO:0016192=IEA, GO:0030669=TAS, GO:0016044=TAS} antigen processing and presentation of exogenous peptide antigen via MHC class II, axon guidance, cellular membrane organization, epidermal growth factor receptor signaling pathway, intracellular protein transport, negative regulation of epidermal growth factor receptor signaling pathway, neurotrophin TRK receptor signaling pathway, regulation of defense response to virus by virus, synaptic transmission, vesicle-mediated transport, viral reproduction clathrin adaptor complex, clathrin coat of coated pit, clathrin-coated endocytic vesicle membrane, cytosol, endocytic vesicle membrane, lysosomal membrane, mitochondrion, plasma membrane lipid binding, protein binding, transporter activity Human AP2S1 Reactome UniProtKB {GO:0005215=PMID:9040778, GO:0048011=Reactome:REACT_11061, GO:0005886=Reactome:REACT_120835, GO:0030122=PMID:10753805, GO:0042059=Reactome:REACT_12484, GO:0007268=Reactome:REACT_13685, GO:0006886=GO_REF:0000002, GO:0050690=Reactome:REACT_11200, GO:0005829=Reactome:REACT_11177, GO:0030666=Reactome:REACT_18330, GO:0019886=Reactome:REACT_121399, GO:0007173=Reactome:REACT_9417, GO:0030100=PMID:10753805, GO:0007411=Reactome:REACT_18266, GO:0008565=PMID:10753805, GO:0016032=Reactome:REACT_6185, GO:0016192=GO_REF:0000002, GO:0030669=Reactome:REACT_121177, GO:0048268=PMID:10753805} P53680 AP-2 complex subunit sigma protein 20130213 {GO:0005215=NAS, GO:0048011=TAS, GO:0005886=TAS, GO:0030122=TAS, GO:0042059=TAS, GO:0007268=TAS, GO:0006886=IEA, GO:0050690=TAS, GO:0005829=TAS, GO:0030666=TAS, GO:0019886=TAS, GO:0007173=TAS, GO:0030100=TAS, GO:0007411=TAS, GO:0008565=NAS, GO:0016032=TAS, GO:0016192=IEA, GO:0030669=TAS, GO:0048268=TAS} antigen processing and presentation of exogenous peptide antigen via MHC class II, axon guidance, clathrin coat assembly, epidermal growth factor receptor signaling pathway, intracellular protein transport, negative regulation of epidermal growth factor receptor signaling pathway, neurotrophin TRK receptor signaling pathway, regulation of defense response to virus by virus, regulation of endocytosis, synaptic transmission, vesicle-mediated transport, viral reproduction AP-2 adaptor complex, clathrin-coated endocytic vesicle membrane, cytosol, endocytic vesicle membrane, plasma membrane protein transporter activity, transporter activity Human AP3B1 PINC UniProtKB {GO:0048490=GO_REF:0000024, GO:0005794=GO_REF:0000039, GO:0019903=PMID:17622474, GO:0032438=PMID:19841138, GO:0030123=GO_REF:0000002, GO:0006886=PMID:9931340, GO:0006897=GO_REF:0000037, GO:0030665=GO_REF:0000039, GO:0007596=GO_REF:0000019, GO:0051138=GO_REF:0000019, GO:0006622=GO_REF:0000019, GO:0048007=GO_REF:0000019, GO:0008089=GO_REF:0000024, GO:0016192=GO_REF:0000002} O00203 AP-3 complex subunit beta-1 protein 20030904 {GO:0048490=ISS, GO:0005794=IEA, GO:0019903=IPI, GO:0032438=IMP, GO:0030123=IEA, GO:0006886=TAS, GO:0006897=IEA, GO:0030665=IEA, GO:0007596=IEA, GO:0051138=IEA, GO:0006622=IEA, GO:0048007=IEA, GO:0008089=ISS, GO:0016192=IEA} anterograde axon cargo transport, anterograde synaptic vesicle transport, antigen processing and presentation, exogenous lipid antigen via MHC class Ib, blood coagulation, endocytosis, intracellular protein transport, melanosome organization, positive regulation of NK T cell differentiation, protein targeting to lysosome, vesicle-mediated transport AP-3 adaptor complex, Golgi apparatus, clathrin-coated vesicle membrane protein phosphatase binding Human AP3B2 HPA UniProtKB {GO:0005215=PMID:7671305, GO:0048490=GO_REF:0000024, GO:0005794=GO_REF:0000052, GO:0030137=PMID:7671305, GO:0030123=GO_REF:0000002, GO:0006892=PMID:7671305, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0006886=GO_REF:0000002, GO:0030117=GO_REF:0000002, GO:0006897=GO_REF:0000037, GO:0030665=GO_REF:0000039, GO:0005737=GO_REF:0000052, GO:0008089=GO_REF:0000024, GO:0016192=GO_REF:0000002} Q13367 AP-3 complex subunit beta-2 protein 20111111 {GO:0005215=TAS, GO:0048490=ISS, GO:0005794=IDA, GO:0030137=TAS, GO:0030123=IEA, GO:0006892=TAS, GO:0005730=IDA, GO:0005634=IDA, GO:0006886=IEA, GO:0030117=IEA, GO:0006897=IEA, GO:0030665=IEA, GO:0005737=IDA, GO:0008089=ISS, GO:0016192=IEA} anterograde axon cargo transport, anterograde synaptic vesicle transport, endocytosis, intracellular protein transport, post-Golgi vesicle-mediated transport, vesicle-mediated transport AP-3 adaptor complex, COPI-coated vesicle, Golgi apparatus, clathrin-coated vesicle membrane, cytoplasm, membrane coat, nucleolus, nucleus transporter activity Human AP3D1 BHF-UCL UniProtKB {GO:0005215=PMID:9303295, GO:0048490=GO_REF:0000024, GO:0006726=PMID:9303295, GO:0005794=PMID:9151686, GO:0033365=GO_REF:0000019, GO:0061088=PMID:17349999, GO:0048499=GO_REF:0000019, GO:0006886=GO_REF:0000019, GO:0030117=GO_REF:0000002, GO:0000139=GO_REF:0000039, GO:0051138=GO_REF:0000019, GO:0043195=GO_REF:0000019, GO:0008565=GO_REF:0000002, GO:0048007=GO_REF:0000019, GO:0008089=GO_REF:0000024, GO:0016192=GO_REF:0000002, GO:0010008=PMID:16162817} O14617 AP-3 complex subunit delta-1 protein 20100505 {GO:0005215=TAS, GO:0048490=ISS, GO:0006726=TAS, GO:0005794=TAS, GO:0033365=IEA, GO:0061088=IMP, GO:0048499=IEA, GO:0006886=IEA, GO:0030117=IEA, GO:0000139=IEA, GO:0051138=IEA, GO:0043195=IEA, GO:0008565=IEA, GO:0048007=IEA, GO:0008089=ISS, GO:0016192=IEA, GO:0010008=IDA} anterograde axon cargo transport, anterograde synaptic vesicle transport, antigen processing and presentation, exogenous lipid antigen via MHC class Ib, eye pigment biosynthetic process, intracellular protein transport, positive regulation of NK T cell differentiation, protein localization to organelle, regulation of sequestering of zinc ion, synaptic vesicle membrane organization, vesicle-mediated transport Golgi apparatus, Golgi membrane, endosome membrane, membrane coat, terminal bouton protein transporter activity, transporter activity Human AP3M1 PINC UniProtKB {GO:0005515=PMID:19116314, GO:0048490=GO_REF:0000024, GO:0030131=GO_REF:0000002, GO:0005794=GO_REF:0000039, GO:0006622=PMID:10024875, GO:0008089=GO_REF:0000024, GO:0005764=PMID:10024875} Q9Y2T2 AP-3 complex subunit mu-1 protein 20030904 {GO:0005515=IPI, GO:0048490=ISS, GO:0030131=IEA, GO:0005794=IEA, GO:0006622=TAS, GO:0008089=ISS, GO:0005764=TAS} anterograde axon cargo transport, anterograde synaptic vesicle transport, protein targeting to lysosome Golgi apparatus, clathrin adaptor complex, lysosome protein binding Human AP3M2 InterPro UniProtKB {GO:0048490=GO_REF:0000024, GO:0030131=GO_REF:0000002, GO:0005794=GO_REF:0000039, GO:0006810=GO_REF:0000002, GO:0008089=GO_REF:0000024, GO:0030119=PMID:8076832, GO:0016192=GO_REF:0000002, GO:0006886=GO_REF:0000002} Q7Z472 AP3M2 protein protein 20130413 {GO:0048490=ISS, GO:0030131=IEA, GO:0005794=IEA, GO:0006810=IEA, GO:0008089=ISS, GO:0030119=TAS, GO:0016192=IEA, GO:0006886=IEA} anterograde axon cargo transport, anterograde synaptic vesicle transport, intracellular protein transport, transport, vesicle-mediated transport AP-type membrane coat adaptor complex, Golgi apparatus, clathrin adaptor complex Human InterPro:IPR001392|InterPro:IPR008968|InterPro:IPR018240 AP3S1 PINC UniProtKB {GO:0005515=PMID:16162817, GO:0030133=PMID:9118953, GO:0008286=PMID:9792713, GO:0005215=PMID:9118953, GO:0048490=GO_REF:0000024, GO:0005794=GO_REF:0000039, GO:0030123=PMID:9118953, GO:0030119=PMID:8697810, GO:0006886=GO_REF:0000002, GO:0008565=GO_REF:0000002, GO:0008089=GO_REF:0000024, GO:0016192=GO_REF:0000002, GO:0030659=GO_REF:0000039} Q92572 AP-3 complex subunit sigma-1 protein 20030904 {GO:0005515=IPI, GO:0030133=TAS, GO:0008286=TAS, GO:0005215=NAS, GO:0048490=ISS, GO:0005794=IEA, GO:0030123=IDA, GO:0030119=TAS, GO:0006886=IEA, GO:0008565=IEA, GO:0008089=ISS, GO:0016192=IEA, GO:0030659=IEA} anterograde axon cargo transport, anterograde synaptic vesicle transport, insulin receptor signaling pathway, intracellular protein transport, vesicle-mediated transport AP-3 adaptor complex, AP-type membrane coat adaptor complex, Golgi apparatus, cytoplasmic vesicle membrane, transport vesicle protein binding, protein transporter activity, transporter activity Human AP3S2 UniProtKB UniProtKB {GO:0048490=GO_REF:0000024, GO:0005794=GO_REF:0000039, GO:0030123=PMID:9118953, GO:0008565=GO_REF:0000002, GO:0006810=GO_REF:0000002, GO:0008089=GO_REF:0000024, GO:0016192=GO_REF:0000002, GO:0006886=GO_REF:0000002, GO:0030659=GO_REF:0000039} P59780 AP-3 complex subunit sigma-2 protein 20120810 {GO:0048490=ISS, GO:0005794=IEA, GO:0030123=IDA, GO:0008565=IEA, GO:0006810=IEA, GO:0008089=ISS, GO:0016192=IEA, GO:0006886=IEA, GO:0030659=IEA} anterograde axon cargo transport, anterograde synaptic vesicle transport, intracellular protein transport, transport, vesicle-mediated transport AP-3 adaptor complex, Golgi apparatus, cytoplasmic vesicle membrane protein transporter activity Human UniProtKB:Q8BSZ2 AP4B1 PINC UniProtKB {GO:0005802=GO_REF:0000019, GO:0005215=PMID:10066790, GO:0030131=GO_REF:0000002, GO:0005794=GO_REF:0000039, GO:0008565=GO_REF:0000002, GO:0016192=GO_REF:0000002, GO:0006886=GO_REF:0000002, GO:0030117=GO_REF:0000002} Q9Y6B7 AP-4 complex subunit beta-1 protein 20030904 {GO:0005802=IEA, GO:0005215=TAS, GO:0030131=IEA, GO:0005794=IEA, GO:0008565=IEA, GO:0016192=IEA, GO:0006886=IEA, GO:0030117=IEA} intracellular protein transport, vesicle-mediated transport Golgi apparatus, clathrin adaptor complex, membrane coat, trans-Golgi network protein transporter activity, transporter activity Human AP4E1 InterPro UniProtKB {GO:0030126=GO_REF:0000002, GO:0005198=GO_REF:0000002, GO:0016192=GO_REF:0000002, GO:0006886=GO_REF:0000002, GO:0030117=GO_REF:0000002} Q9UPM8 AP-4 complex subunit epsilon-1 protein 20130413 {GO:0030126=IEA, GO:0005198=IEA, GO:0016192=IEA, GO:0006886=IEA, GO:0030117=IEA} intracellular protein transport, vesicle-mediated transport COPI vesicle coat, membrane coat structural molecule activity Human InterPro:IPR011710 AP4M1 PINC UniProtKB {GO:0005802=PMID:20230749, GO:0005215=PMID:10066790, GO:0005905=GO_REF:0000039, GO:0030131=GO_REF:0000002, GO:0000138=PMID:10066790, GO:0006810=GO_REF:0000002, GO:0030119=PMID:10066790, GO:0016192=PMID:10066790, GO:0006895=PMID:20230749, GO:0006886=PMID:20230749} O00189 AP-4 complex subunit mu-1 protein 20030904 {GO:0005802=IDA, GO:0005215=TAS, GO:0005905=IEA, GO:0030131=IEA, GO:0000138=TAS, GO:0006810=IEA, GO:0030119=TAS, GO:0016192=TAS, GO:0006895=IMP, GO:0006886=IMP} Golgi to endosome transport, intracellular protein transport, transport, vesicle-mediated transport AP-type membrane coat adaptor complex, Golgi trans cisterna, clathrin adaptor complex, coated pit, trans-Golgi network transporter activity Human AP4S1 PINC UniProtKB {GO:0005215=PMID:10436028, GO:0005905=GO_REF:0000039, GO:0005794=GO_REF:0000039, GO:0008565=GO_REF:0000002} Q9Y587 AP-4 complex subunit sigma-1 protein 20030904 {GO:0005215=TAS, GO:0005905=IEA, GO:0005794=IEA, GO:0008565=IEA} Golgi apparatus, coated pit protein transporter activity, transporter activity Human APAF1 HPA UniProtKB {GO:0005515=PMID:17274640, GO:0008635=Reactome:REACT_607, GO:0005794=GO_REF:0000052, GO:0006919=PMID:21827945, GO:0005730=GO_REF:0000052, GO:0006915=Reactome:REACT_578, GO:0001843=GO_REF:0000019, GO:0006952=GO_REF:0000002, GO:0042981=PMID:10441496, GO:0005634=GO_REF:0000052, GO:0051402=GO_REF:0000019, GO:0008656=PMID:15009102, GO:0005524=GO_REF:0000037, GO:0097193=Reactome:REACT_964, GO:0005829=Reactome:REACT_2165, GO:0007399=PMID:9753320, GO:0042802=GO_REF:0000019, GO:0005622=GO_REF:0000002, GO:0005737=GO_REF:0000052, GO:0043293=PMID:21827945, GO:0000166=PMID:10383829, GO:0043531=GO_REF:0000002, GO:0006309=GO_REF:0000019, GO:0030900=GO_REF:0000019} O14727 Apoptotic protease-activating factor 1 protein 20101115 {GO:0005515=IPI, GO:0008635=TAS, GO:0005794=IDA, GO:0006919=IDA, GO:0005730=IDA, GO:0006915=TAS, GO:0001843=IEA, GO:0006952=IEA, GO:0042981=TAS, GO:0005634=IDA, GO:0051402=IEA, GO:0008656=NAS, GO:0005524=IEA, GO:0097193=TAS, GO:0005829=TAS, GO:0007399=TAS, GO:0042802=IEA, GO:0005622=IEA, GO:0005737=IDA, GO:0043293=IDA, GO:0000166=TAS, GO:0043531=IEA, GO:0006309=IEA, GO:0030900=IEA} activation of cysteine-type endopeptidase activity involved in apoptotic process, activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c, apoptotic DNA fragmentation, apoptotic process, defense response, forebrain development, intrinsic apoptotic signaling pathway, nervous system development, neural tube closure, neuron apoptotic process, regulation of apoptotic process Golgi apparatus, apoptosome, cytoplasm, cytosol, intracellular, nucleolus, nucleus ADP binding, ATP binding, cysteine-type endopeptidase activator activity involved in apoptotic process, identical protein binding, nucleotide binding, protein binding Human APBA1 IntAct UniProtKB {GO:0005515=PMID:8887653, GO:0010468=GO_REF:0000019, GO:0005886=GO_REF:0000019, GO:0014051=GO_REF:0000019, GO:0005546=GO_REF:0000019, GO:0007268=GO_REF:0000019, GO:0005634=GO_REF:0000039, GO:0030165=GO_REF:0000019, GO:0006886=GO_REF:0000019, GO:0014047=GO_REF:0000019, GO:0032403=GO_REF:0000019, GO:0001701=GO_REF:0000019, GO:0008021=PMID:9753324, GO:0007399=PMID:9753324, GO:0043234=GO_REF:0000019, GO:0006461=PMID:9753324, GO:0001540=GO_REF:0000019, GO:0035264=GO_REF:0000019, GO:0008088=PMID:9822620, GO:0007626=GO_REF:0000019, GO:0007155=PMID:9753324} Q02410 Amyloid beta A4 precursor protein-binding family A member 1 protein 20130415 {GO:0005515=IPI, GO:0010468=IEA, GO:0005886=IEA, GO:0014051=IEA, GO:0005546=IEA, GO:0007268=IEA, GO:0005634=IEA, GO:0030165=IEA, GO:0006886=IEA, GO:0014047=IEA, GO:0032403=IEA, GO:0001701=IEA, GO:0008021=TAS, GO:0007399=TAS, GO:0043234=IEA, GO:0006461=TAS, GO:0001540=IEA, GO:0035264=IEA, GO:0008088=TAS, GO:0007626=IEA, GO:0007155=TAS} axon cargo transport, cell adhesion, gamma-aminobutyric acid secretion, glutamate secretion, in utero embryonic development, intracellular protein transport, locomotory behavior, multicellular organism growth, nervous system development, protein complex assembly, regulation of gene expression, synaptic transmission nucleus, plasma membrane, protein complex, synaptic vesicle PDZ domain binding, beta-amyloid binding, phosphatidylinositol-4,5-bisphosphate binding, protein binding, protein complex binding Human UniProtKB:P05067 APBA2 PINC UniProtKB {GO:0005515=PMID:10833507, GO:0010468=GO_REF:0000019, GO:0001540=GO_REF:0000019, GO:0035264=GO_REF:0000019, GO:0005886=GO_REF:0000019, GO:0007268=GO_REF:0000019, GO:0007626=GO_REF:0000019, GO:0015031=GO_REF:0000037, GO:0001701=GO_REF:0000019, GO:0007399=PMID:9890987} Q99767 Amyloid beta A4 precursor protein-binding family A member 2 protein 20030904 {GO:0005515=IPI, GO:0010468=IEA, GO:0001540=IEA, GO:0035264=IEA, GO:0005886=IEA, GO:0007268=IEA, GO:0007626=IEA, GO:0015031=IEA, GO:0001701=IEA, GO:0007399=TAS} in utero embryonic development, locomotory behavior, multicellular organism growth, nervous system development, protein transport, regulation of gene expression, synaptic transmission plasma membrane beta-amyloid binding, protein binding Human APBA3 IntAct UniProtKB {GO:0004857=PMID:19726677, GO:0035556=GO_REF:0000029, GO:0005515=PMID:21903422, GO:0010468=GO_REF:0000019, GO:0048471=PMID:19726677, GO:0001540=GO_REF:0000019, GO:0016020=GO_REF:0000029, GO:0007268=GO_REF:0000019, GO:0019899=PMID:19726677, GO:0015031=GO_REF:0000037, GO:0043086=PMID:19726677, GO:0001701=GO_REF:0000019} O96018 Amyloid beta A4 precursor protein-binding family A member 3 protein 20130415 {GO:0004857=IDA, GO:0035556=NAS, GO:0005515=IPI, GO:0010468=IEA, GO:0048471=IDA, GO:0001540=IEA, GO:0016020=NAS, GO:0007268=IEA, GO:0019899=IPI, GO:0015031=IEA, GO:0043086=IDA, GO:0001701=IEA} in utero embryonic development, intracellular signal transduction, negative regulation of catalytic activity, protein transport, regulation of gene expression, synaptic transmission membrane, perinuclear region of cytoplasm beta-amyloid binding, enzyme binding, enzyme inhibitor activity, protein binding Human UniProtKB:Q9QYP6 APBB1 IntAct UniProtKB {GO:0005515=PMID:16049941, GO:0030308=GO_REF:0000024, GO:0005886=PMID:18468999, GO:0045202=PMID:12843239, GO:0005634=PMID:19343227, GO:0045739=GO_REF:0000019, GO:0007409=PMID:12843239, GO:0006302=GO_REF:0000019, GO:0030426=PMID:12843239, GO:0042393=PMID:19234442, GO:0005737=PMID:18468999, GO:0001540=PMID:18468999, GO:0030198=GO_REF:0000019, GO:0007411=GO_REF:0000019, GO:0007050=GO_REF:0000024, GO:0050760=GO_REF:0000024, GO:0070064=PMID:17686488, GO:0006355=GO_REF:0000024, GO:0043065=PMID:18468999, GO:0006915=GO_REF:0000037, GO:0045749=GO_REF:0000024, GO:0006351=GO_REF:0000037, GO:0030027=PMID:12843239, GO:0006974=PMID:18468999, GO:0007165=PMID:8894693, GO:0016607=GO_REF:0000039, GO:0045665=GO_REF:0000019, GO:0043967=GO_REF:0000024, GO:0003682=PMID:19343227, GO:0008542=GO_REF:0000019, GO:0045893=PMID:19343227, GO:0001764=GO_REF:0000019, GO:0008134=GO_REF:0000024} O00213 Amyloid beta A4 precursor protein-binding family B member 1 protein 20130415 {GO:0005515=IPI, GO:0030308=ISS, GO:0005886=IDA, GO:0045202=IDA, GO:0005634=IDA, GO:0045739=IEA, GO:0007409=NAS, GO:0006302=IEA, GO:0030426=IDA, GO:0042393=IPI, GO:0005737=IDA, GO:0001540=IPI, GO:0030198=IEA, GO:0007411=IEA, GO:0007050=ISS, GO:0050760=ISS, GO:0070064=IPI, GO:0006355=ISS, GO:0043065=IDA, GO:0006915=IEA, GO:0045749=ISS, GO:0006351=IEA, GO:0030027=IDA, GO:0006974=IDA, GO:0007165=NAS, GO:0016607=IEA, GO:0045665=IEA, GO:0043967=ISS, GO:0003682=IDA, GO:0008542=IEA, GO:0045893=IDA, GO:0001764=IEA, GO:0008134=ISS} apoptotic process, axon guidance, axonogenesis, cell cycle arrest, double-strand break repair, extracellular matrix organization, histone H4 acetylation, negative regulation of S phase of mitotic cell cycle, negative regulation of cell growth, negative regulation of neuron differentiation, negative regulation of thymidylate synthase biosynthetic process, neuron migration, positive regulation of DNA repair, positive regulation of apoptotic process, positive regulation of transcription, DNA-dependent, regulation of transcription, DNA-dependent, response to DNA damage stimulus, signal transduction, transcription, DNA-dependent, visual learning cytoplasm, growth cone, lamellipodium, nuclear speck, nucleus, plasma membrane, synapse beta-amyloid binding, chromatin binding, histone binding, proline-rich region binding, protein binding, transcription factor binding Human UniProtKB:P05067 APBB1IP InterPro UniProtKB {GO:0007165=GO_REF:0000002, GO:0005543=GO_REF:0000002, GO:0005886=GO_REF:0000039, GO:0007596=Reactome:REACT_604, GO:0030168=Reactome:REACT_798, GO:0005856=GO_REF:0000039, GO:0005925=GO_REF:0000039, GO:0030027=GO_REF:0000039, GO:0005829=Reactome:REACT_23931} Q9NWJ6 cDNA FLJ20805 fis, clone ADSE02009 protein 20130413 {GO:0007165=IEA, GO:0005543=IEA, GO:0005886=IEA, GO:0007596=TAS, GO:0030168=TAS, GO:0005856=IEA, GO:0005925=IEA, GO:0030027=IEA, GO:0005829=TAS} blood coagulation, platelet activation, signal transduction cytoskeleton, cytosol, focal adhesion, lamellipodium, plasma membrane phospholipid binding Human InterPro:IPR000159 APBB2 IntAct UniProtKB {GO:0005515=PMID:8855266, GO:0006355=GO_REF:0000024, GO:0030308=GO_REF:0000024, GO:0043066=GO_REF:0000019, GO:0043065=GO_REF:0000019, GO:0045202=GO_REF:0000024, GO:0005634=GO_REF:0000024, GO:0030027=GO_REF:0000024, GO:0045749=GO_REF:0000024, GO:0030426=GO_REF:0000024, GO:0035556=PMID:8855266, GO:0005737=GO_REF:0000019, GO:0001540=GO_REF:0000024, GO:0016020=PMID:8855266, GO:0007411=GO_REF:0000019, GO:0030198=GO_REF:0000019, GO:0007050=GO_REF:0000024, GO:0001764=GO_REF:0000019, GO:0008134=GO_REF:0000024} Q92870 Amyloid beta A4 precursor protein-binding family B member 2 protein 20130415 {GO:0005515=IPI, GO:0006355=ISS, GO:0030308=ISS, GO:0043066=IEA, GO:0043065=IEA, GO:0045202=ISS, GO:0005634=ISS, GO:0030027=ISS, GO:0045749=ISS, GO:0030426=ISS, GO:0035556=NAS, GO:0005737=IEA, GO:0001540=ISS, GO:0016020=NAS, GO:0007411=IEA, GO:0030198=IEA, GO:0007050=ISS, GO:0001764=IEA, GO:0008134=ISS} axon guidance, cell cycle arrest, extracellular matrix organization, intracellular signal transduction, negative regulation of S phase of mitotic cell cycle, negative regulation of apoptotic process, negative regulation of cell growth, neuron migration, positive regulation of apoptotic process, regulation of transcription, DNA-dependent cytoplasm, growth cone, lamellipodium, membrane, nucleus, synapse beta-amyloid binding, protein binding, transcription factor binding Human UniProtKB:P05067 APBB3 HPA UniProtKB {GO:0005737=GO_REF:0000052, GO:0015629=GO_REF:0000052} O95704 Amyloid beta A4 precursor protein-binding family B member 3 protein 20080818 {GO:0005737=IDA, GO:0015629=IDA} actin cytoskeleton, cytoplasm Human APC BHF-UCL UniProtKB {GO:0008017=PMID:16188939, GO:0005515=PMID:22682247, GO:0009798=GO_REF:0000019, GO:0008013=PMID:7890674, GO:0051171=GO_REF:0000019, GO:0060041=GO_REF:0000019, GO:0030877=PMID:16188939, GO:0031122=GO_REF:0000019, GO:0035371=GO_REF:0000019, GO:0048538=GO_REF:0000019, GO:0007409=GO_REF:0000019, GO:0070830=PMID:18502210, GO:0051010=PMID:19632184, GO:0031274=PMID:17192415, GO:0051781=GO_REF:0000019, GO:0016055=GO_REF:0000002, GO:0001942=GO_REF:0000019, GO:0005813=PMID:11283619, GO:0033077=GO_REF:0000019, GO:0045296=PMID:7890674, GO:0030335=PMID:17192415, GO:0045295=PMID:7890674, GO:0019901=PMID:8638126, GO:0000281=PMID:17570218, GO:0030027=PMID:19151759, GO:0045785=GO_REF:0000019, GO:0000776=PMID:11283619, GO:0043588=GO_REF:0000019, GO:0005923=PMID:18502210, GO:0060770=GO_REF:0000019, GO:0007094=PMID:17227893, GO:0005881=GO_REF:0000019, GO:0045732=PMID:16188939, GO:0051276=GO_REF:0000019, GO:0008285=PMID:8521819, GO:0005886=PMID:16611247, GO:0042483=GO_REF:0000019, GO:0045736=PMID:8521819, GO:0030178=GO_REF:0000002, GO:0009954=GO_REF:0000019, GO:0005634=PMID:12072559, GO:0009953=GO_REF:0000019, GO:0009952=GO_REF:0000019, GO:0006921=Reactome:REACT_995, GO:0046716=GO_REF:0000019, GO:0005829=Reactome:REACT_12012, GO:0019887=PMID:11972058, GO:0043409=GO_REF:0000019, GO:0030858=GO_REF:0000019, GO:0005737=PMID:20937854, GO:0005913=PMID:16611247, GO:0007050=PMID:8521819, GO:0007155=PMID:8259518, GO:0090090=PMID:12952940, GO:0060070=PMID:9601641, GO:0007091=GO_REF:0000019, GO:0035019=GO_REF:0000019, GO:0031253=GO_REF:0000019, GO:0043066=GO_REF:0000019, GO:0031116=GO_REF:0000019, GO:0043065=PMID:17227893, GO:0001822=GO_REF:0000019, GO:0051988=PMID:17227893, GO:0006915=Reactome:REACT_578, GO:0032886=PMID:20937854, GO:0032587=PMID:19151759, GO:0045670=GO_REF:0000019, GO:0044295=GO_REF:0000019, GO:0016328=PMID:12072559, GO:0006974=PMID:14728717, GO:0045667=GO_REF:0000019, GO:0006461=PMID:16188939, GO:0016477=PMID:19151759, GO:0007026=PMID:17192415} P25054 Adenomatous polyposis coli protein protein 20100825 {GO:0008017=IDA, GO:0005515=IPI, GO:0009798=IEA, GO:0008013=IPI, GO:0051171=IEA, GO:0060041=IEA, GO:0030877=IDA, GO:0031122=IEA, GO:0035371=IEA, GO:0048538=IEA, GO:0007409=IEA, GO:0070830=NAS, GO:0051010=IDA, GO:0031274=IMP, GO:0051781=IEA, GO:0016055=IEA, GO:0001942=IEA, GO:0005813=IDA, GO:0033077=IEA, GO:0045296=IDA, GO:0030335=IMP, GO:0045295=IPI, GO:0019901=IPI, GO:0000281=IMP, GO:0030027=IDA, GO:0045785=IEA, GO:0000776=IDA, GO:0043588=IEA, GO:0005923=IDA, GO:0060770=IEA, GO:0007094=IMP, GO:0005881=IEA, GO:0045732=IC, GO:0051276=IEA, GO:0008285=IDA, GO:0005886=IDA, GO:0042483=IEA, GO:0045736=IDA, GO:0030178=IEA, GO:0009954=IEA, GO:0005634=IDA, GO:0009953=IEA, GO:0009952=IEA, GO:0006921=TAS, GO:0046716=IEA, GO:0005829=TAS, GO:0019887=IDA, GO:0043409=IEA, GO:0030858=IEA, GO:0005737=IDA, GO:0005913=IDA, GO:0007050=IDA, GO:0007155=NAS, GO:0090090=IGI, GO:0060070=IC, GO:0007091=IEA, GO:0035019=IEA, GO:0031253=IEA, GO:0043066=IEA, GO:0031116=IEA, GO:0043065=IMP, GO:0001822=IEA, GO:0051988=IMP, GO:0006915=TAS, GO:0032886=IMP, GO:0032587=IDA, GO:0045670=IEA, GO:0044295=IEA, GO:0016328=IDA, GO:0006974=IDA, GO:0045667=IEA, GO:0006461=IDA, GO:0016477=IMP, GO:0007026=IMP} T cell differentiation in thymus, Wnt receptor signaling pathway, anterior/posterior pattern specification, apoptotic process, axis specification, axonogenesis, canonical Wnt receptor signaling pathway, cell adhesion, cell cycle arrest, cell migration, cellular component disassembly involved in execution phase of apoptosis, chromosome organization, cytokinesis after mitosis, cytoplasmic microtubule organization, dorsal/ventral pattern formation, hair follicle development, kidney development, metaphase/anaphase transition of mitotic cell cycle, mitotic spindle assembly checkpoint, muscle cell homeostasis, negative regulation of MAPK cascade, negative regulation of Wnt receptor signaling pathway, negative regulation of apoptotic process, negative regulation of canonical Wnt receptor signaling pathway, negative regulation of cell proliferation, negative regulation of cyclin-dependent protein serine/threonine kinase activity, negative regulation of epithelial cell proliferation involved in prostate gland development, negative regulation of microtubule depolymerization, negative regulation of odontogenesis, positive regulation of apoptotic process, positive regulation of cell adhesion, positive regulation of cell division, positive regulation of cell migration, positive regulation of epithelial cell differentiation, positive regulation of microtubule polymerization, positive regulation of protein catabolic process, positive regulation of pseudopodium assembly, protein complex assembly, proximal/distal pattern formation, regulation of attachment of spindle microtubules to kinetochore, regulation of microtubule-based process, regulation of nitrogen compound metabolic process, regulation of osteoblast differentiation, regulation of osteoclast differentiation, response to DNA damage stimulus, retina development in camera-type eye, skin development, somatic stem cell maintenance, thymus development, tight junction assembly axonal growth cone, beta-catenin destruction complex, cell projection membrane, cell-cell adherens junction, centrosome, cytoplasm, cytoplasmic microtubule, cytosol, kinetochore, lamellipodium, lateral plasma membrane, microtubule plus end, nucleus, plasma membrane, ruffle membrane, tight junction beta-catenin binding, cadherin binding, gamma-catenin binding, microtubule binding, microtubule plus-end binding, protein binding, protein kinase binding, protein kinase regulator activity colocalizes_with Human APC2 BHF-UCL UniProtKB {GO:0008017=GO_REF:0000002, GO:0005515=PMID:10646860, GO:0005881=PMID:11691822, GO:0048471=PMID:10646860, GO:0005794=PMID:11691822, GO:0031258=PMID:11691822, GO:0008013=PMID:9823329, GO:0005884=PMID:11691822, GO:0016342=PMID:9823329, GO:0035414=PMID:10021369, GO:0005737=PMID:11691822, GO:0000139=GO_REF:0000039, GO:0016055=GO_REF:0000037, GO:0090090=PMID:10021369} O95996 Adenomatous polyposis coli protein 2 protein 20101014 {GO:0008017=IEA, GO:0005515=IPI, GO:0005881=IMP, GO:0048471=IDA, GO:0005794=IDA, GO:0031258=IDA, GO:0008013=IDA, GO:0005884=IDA, GO:0016342=IDA, GO:0035414=IDA, GO:0005737=IDA, GO:0000139=IEA, GO:0016055=IEA, GO:0090090=IDA} Wnt receptor signaling pathway, negative regulation of canonical Wnt receptor signaling pathway, negative regulation of catenin import into nucleus Golgi apparatus, Golgi membrane, actin filament, catenin complex, cytoplasm, cytoplasmic microtubule, lamellipodium membrane, perinuclear region of cytoplasm beta-catenin binding, microtubule binding, protein binding Human APCDD1 UniProtKB UniProtKB {GO:0017147=PMID:20393562, GO:0005887=PMID:20393562, GO:0030178=PMID:20393562, GO:0016055=GO_REF:0000037, GO:0001942=PMID:20393562} Q8J025 Protein APCDD1 protein 20100423 {GO:0017147=IDA, GO:0005887=IDA, GO:0030178=IDA, GO:0016055=IEA, GO:0001942=IMP} Wnt receptor signaling pathway, hair follicle development, negative regulation of Wnt receptor signaling pathway integral to plasma membrane Wnt-protein binding Human APCS Reactome UniProtKB {GO:0043234=GO_REF:0000019, GO:0006457=PMID:10812074, GO:0005576=Reactome:REACT_75905, GO:0051082=PMID:10812074, GO:0006953=PMID:2987268, GO:0051131=PMID:10972085, GO:0046872=GO_REF:0000037} P02743 Serum amyloid P-component protein 20101013 {GO:0043234=IEA, GO:0006457=TAS, GO:0005576=TAS, GO:0051082=TAS, GO:0006953=TAS, GO:0051131=TAS, GO:0046872=IEA} acute-phase response, chaperone-mediated protein complex assembly, protein folding extracellular region, protein complex metal ion binding, unfolded protein binding Human APEH HPA UniProtKB {GO:0031965=GO_REF:0000052, GO:0005737=GO_REF:0000052, GO:0004252=GO_REF:0000002, GO:0006508=GO_REF:0000002} P13798 Acylamino-acid-releasing enzyme protein 20101115 {GO:0031965=IDA, GO:0005737=IDA, GO:0004252=IEA, GO:0006508=IEA} proteolysis cytoplasm, nuclear membrane serine-type endopeptidase activity Human APEX1 GOC UniProtKB {GO:0005515=PMID:20856196, GO:0003906=PMID:19188445, GO:0004844=PMID:10805771, GO:0008408=PMID:11832948, GO:0070301=GO_REF:0000019, GO:0032403=GO_REF:0000019, GO:0005622=GO_REF:0000002, GO:0004528=PMID:9119221, GO:0004523=PMID:11286553, GO:0080111=PMID:21496894, GO:0043488=PMID:19401441, GO:0005813=GO_REF:0000052, GO:0008081=PMID:11478795, GO:0003714=PMID:7961715, GO:0007568=GO_REF:0000019, GO:0003713=PMID:9119221, GO:0004520=PMID:1722334, GO:0004521=GO_REF:0000019, GO:0031490=PMID:11809897, GO:0004519=PMID:11478795, GO:0006281=Reactome:REACT_216, GO:0006284=Reactome:REACT_1104, GO:0016491=PMID:12524539, GO:0045750=GO_REF:0000019, GO:0045454=GO_REF:0000019, GO:0005654=Reactome:REACT_2224, GO:0055114=PMID:9119221, GO:0048471=PMID:12524539, GO:0016890=PMID:19188445, GO:0005783=PMID:12524539, GO:0003723=GO_REF:0000037, GO:0005634=GO_REF:0000052, GO:0045739=PMID:9207062, GO:0014912=GO_REF:0000019, GO:0046872=PMID:11286553, GO:0005739=PMID:20231292, GO:0005737=PMID:9560228, GO:0071375=GO_REF:0000019, GO:0005667=GO_REF:0000019, GO:0006355=GO_REF:0000037, GO:0051059=GO_REF:0000019, GO:0042493=GO_REF:0000019, GO:0005730=PMID:17148573, GO:0006310=GO_REF:0000037, GO:0003677=PMID:11286553, GO:0006351=GO_REF:0000037, GO:0003684=PMID:12524539, GO:0016607=PMID:17148573, GO:0005840=PMID:12524539, GO:0071320=GO_REF:0000019} P27695 DNA-(apurinic or apyrimidinic site) lyase protein 20130413 {GO:0005515=IPI, GO:0003906=IDA, GO:0004844=TAS, GO:0008408=IDA, GO:0070301=IEA, GO:0032403=IEA, GO:0005622=IEA, GO:0004528=TAS, GO:0004523=TAS, GO:0080111=IDA, GO:0043488=IMP, GO:0005813=IDA, GO:0008081=IDA, GO:0003714=TAS, GO:0007568=IEA, GO:0003713=IDA, GO:0004520=TAS, GO:0004521=IEA, GO:0031490=IDA, GO:0004519=IDA, GO:0006281=TAS, GO:0006284=TAS, GO:0016491=IDA, GO:0045750=IEA, GO:0045454=IEA, GO:0005654=TAS, GO:0055114=IDA, GO:0048471=IDA, GO:0016890=IDA, GO:0005783=TAS, GO:0003723=IEA, GO:0005634=IDA, GO:0045739=IDA, GO:0014912=IEA, GO:0046872=IDA, GO:0005739=IDA, GO:0005737=IDA, GO:0071375=IEA, GO:0005667=IEA, GO:0006355=IEA, GO:0051059=IEA, GO:0042493=IEA, GO:0005730=IDA, GO:0006310=IEA, GO:0003677=IDA, GO:0006351=IEA, GO:0003684=IDA, GO:0016607=IDA, GO:0005840=TAS, GO:0071320=IEA} DNA demethylation, DNA recombination, DNA repair, aging, base-excision repair, cell redox homeostasis, cellular response to cAMP, cellular response to hydrogen peroxide, cellular response to peptide hormone stimulus, negative regulation of smooth muscle cell migration, oxidation-reduction process, positive regulation of DNA repair, positive regulation of S phase of mitotic cell cycle, regulation of mRNA stability, regulation of transcription, DNA-dependent, response to drug, transcription, DNA-dependent centrosome, cytoplasm, endoplasmic reticulum, intracellular, mitochondrion, nuclear speck, nucleolus, nucleoplasm, nucleus, perinuclear region of cytoplasm, ribosome, transcription factor complex 3'-5' exonuclease activity, DNA binding, DNA-(apurinic or apyrimidinic site) lyase activity, NF-kappaB binding, RNA binding, chromatin DNA binding, damaged DNA binding, endodeoxyribonuclease activity, endonuclease activity, endoribonuclease activity, metal ion binding, oxidoreductase activity, phosphodiesterase I activity, phosphoric diester hydrolase activity, protein binding, protein complex binding, ribonuclease H activity, site-specific endodeoxyribonuclease activity, specific for altered base, transcription coactivator activity, transcription corepressor activity, uracil DNA N-glycosylase activity Human APEX2 UniProtKB UniProtKB {GO:0003906=GO_REF:0000003, GO:0007049=GO_REF:0000037, GO:0004527=GO_REF:0000037, GO:0006281=GO_REF:0000037, GO:0004519=GO_REF:0000037, GO:0005743=GO_REF:0000019, GO:0005634=GO_REF:0000039, GO:0006310=GO_REF:0000037, GO:0008270=GO_REF:0000002, GO:0003677=GO_REF:0000037} Q9UBZ4 DNA-(apurinic or apyrimidinic site) lyase 2 protein 20130413 {GO:0003906=IEA, GO:0007049=IEA, GO:0004527=IEA, GO:0006281=IEA, GO:0004519=IEA, GO:0005743=IEA, GO:0005634=IEA, GO:0006310=IEA, GO:0008270=IEA, GO:0003677=IEA} DNA recombination, DNA repair, cell cycle mitochondrial inner membrane, nucleus DNA binding, DNA-(apurinic or apyrimidinic site) lyase activity, endonuclease activity, exonuclease activity, zinc ion binding Human UniProtKB-SubCell:SL-0191 APH1A Reactome UniProtKB {GO:0001656=GO_REF:0000019, GO:0005515=PMID:12297508, GO:0042987=PMID:15274632, GO:0048011=Reactome:REACT_13776, GO:0007220=Reactome:REACT_691, GO:0005794=PMID:15274632, GO:0005886=Reactome:REACT_160171, GO:0031293=Reactome:REACT_13443, GO:0005783=PMID:15274632, GO:0006915=Reactome:REACT_13643, GO:0043085=PMID:15274632, GO:0097190=Reactome:REACT_13720, GO:0007219=Reactome:REACT_118862, GO:0004175=GO_REF:0000019, GO:0005887=PMID:15274632, GO:0016485=PMID:15274632, GO:0032580=GO_REF:0000039, GO:0005789=GO_REF:0000039, GO:0006509=PMID:15274632, GO:0016021=GO_REF:0000002} Q96BI3 Gamma-secretase subunit APH-1A protein 20130301 {GO:0001656=IEA, GO:0005515=IPI, GO:0042987=TAS, GO:0048011=TAS, GO:0007220=TAS, GO:0005794=IDA, GO:0005886=TAS, GO:0031293=TAS, GO:0005783=IDA, GO:0006915=TAS, GO:0043085=IDA, GO:0097190=TAS, GO:0007219=TAS, GO:0004175=IEA, GO:0005887=IDA, GO:0016485=IDA, GO:0032580=IEA, GO:0005789=IEA, GO:0006509=IDA, GO:0016021=IEA} Notch receptor processing, Notch signaling pathway, amyloid precursor protein catabolic process, apoptotic process, apoptotic signaling pathway, membrane protein ectodomain proteolysis, membrane protein intracellular domain proteolysis, metanephros development, neurotrophin TRK receptor signaling pathway, positive regulation of catalytic activity, protein processing Golgi apparatus, Golgi cisterna membrane, endoplasmic reticulum, endoplasmic reticulum membrane, integral to membrane, integral to plasma membrane, plasma membrane endopeptidase activity, protein binding Human APH1B Reactome UniProtKB {GO:0005515=PMID:12297508, GO:0030133=GO_REF:0000054, GO:0048011=Reactome:REACT_13776, GO:0007220=Reactome:REACT_691, GO:0005886=Reactome:REACT_160171, GO:0031293=Reactome:REACT_13443, GO:0006915=Reactome:REACT_13643, GO:0043085=GO_REF:0000002, GO:0097190=Reactome:REACT_13720, GO:0007219=Reactome:REACT_118862, GO:0016485=PMID:12297508, GO:0008233=PMID:12297508, GO:0016021=PMID:12297508} Q8WW43 Gamma-secretase subunit APH-1B protein 20130301 {GO:0005515=IPI, GO:0030133=IDA, GO:0048011=TAS, GO:0007220=TAS, GO:0005886=TAS, GO:0031293=TAS, GO:0006915=TAS, GO:0043085=IEA, GO:0097190=TAS, GO:0007219=TAS, GO:0016485=IDA, GO:0008233=IDA, GO:0016021=IDA} Notch receptor processing, Notch signaling pathway, apoptotic process, apoptotic signaling pathway, membrane protein intracellular domain proteolysis, neurotrophin TRK receptor signaling pathway, positive regulation of catalytic activity, protein processing integral to membrane, plasma membrane, transport vesicle peptidase activity, protein binding Human API5 HPA UniProtKB {GO:0005737=PMID:11075807, GO:0043066=PMID:10780674, GO:0017134=PMID:11075807, GO:0005730=GO_REF:0000052, GO:0006915=GO_REF:0000037, GO:0005681=PMID:11555636, GO:0005634=GO_REF:0000052} Q9BZZ5 Apoptosis inhibitor 5 protein 20100326 {GO:0005737=NAS, GO:0043066=NAS, GO:0017134=IPI, GO:0005730=IDA, GO:0006915=IEA, GO:0005681=ISS, GO:0005634=IDA} apoptotic process, negative regulation of apoptotic process cytoplasm, nucleolus, nucleus, spliceosomal complex fibroblast growth factor binding NOT Human APIP IntAct UniProtKB {GO:0005515=PMID:19060904, GO:0043066=PMID:22837397, GO:0006915=GO_REF:0000037, GO:0044281=Reactome:REACT_111217, GO:0046872=GO_REF:0000037, GO:0042802=PMID:19060904, GO:0005829=Reactome:REACT_75828, GO:0034641=Reactome:REACT_13, GO:0005737=GO_REF:0000002, GO:0000096=Reactome:REACT_115639, GO:0019509=Reactome:REACT_75881, GO:0006595=Reactome:REACT_14820, GO:0070372=GO_REF:0000024, GO:0046570=Reactome:REACT_75828} Q96GX9 Methylthioribulose-1-phosphate dehydratase protein 20130415 {GO:0005515=IPI, GO:0043066=IMP, GO:0006915=IEA, GO:0044281=TAS, GO:0046872=IEA, GO:0042802=IPI, GO:0005829=TAS, GO:0034641=TAS, GO:0005737=IEA, GO:0000096=TAS, GO:0019509=TAS, GO:0006595=TAS, GO:0070372=ISS, GO:0046570=TAS} L-methionine salvage from methylthioadenosine, apoptotic process, cellular nitrogen compound metabolic process, negative regulation of apoptotic process, polyamine metabolic process, regulation of ERK1 and ERK2 cascade, small molecule metabolic process, sulfur amino acid metabolic process cytoplasm, cytosol identical protein binding, metal ion binding, methylthioribulose 1-phosphate dehydratase activity, protein binding Human UniProtKB:Q96GX9 APITD1 IntAct UniProtKB {GO:0005515=PMID:22304917, GO:0000236=Reactome:REACT_682, GO:0006352=GO_REF:0000002, GO:0071821=PMID:20347428, GO:0046982=GO_REF:0000002, GO:0003677=PMID:20347429, GO:0006974=PMID:20347428, GO:0005829=Reactome:REACT_150414, GO:0043240=PMID:20347428, GO:0003690=PMID:20347428, GO:0006281=PMID:20347429, GO:0003682=PMID:20347429, GO:0000712=PMID:20347428, GO:0000087=Reactome:REACT_910, GO:0031398=PMID:20347428, GO:0000777=GO_REF:0000039, GO:0031297=PMID:20347428, GO:0000278=Reactome:REACT_152, GO:0000090=Reactome:REACT_1275, GO:0051301=GO_REF:0000037} Q8N2Z9 Centromere protein S protein 20130415 {GO:0005515=IPI, GO:0000236=TAS, GO:0006352=IEA, GO:0071821=IDA, GO:0046982=IEA, GO:0003677=IDA, GO:0006974=IMP, GO:0005829=TAS, GO:0043240=IDA, GO:0003690=IDA, GO:0006281=IDA, GO:0003682=IDA, GO:0000712=IMP, GO:0000087=TAS, GO:0031398=TAS, GO:0000777=IEA, GO:0031297=IMP, GO:0000278=TAS, GO:0000090=TAS, GO:0051301=IEA} DNA repair, DNA-dependent transcription, initiation, M phase of mitotic cell cycle, cell division, mitotic anaphase, mitotic cell cycle, mitotic prometaphase, positive regulation of protein ubiquitination, replication fork processing, resolution of meiotic recombination intermediates, response to DNA damage stimulus FANCM-MHF complex, Fanconi anaemia nuclear complex, condensed chromosome kinetochore, cytosol DNA binding, chromatin binding, double-stranded DNA binding, protein binding, protein heterodimerization activity Human UniProtKB:A8MT69 APLF UniProtKB UniProtKB {GO:0003906=PMID:17396150, GO:0005515=PMID:17396150, GO:0000012=PMID:17396150, GO:0008408=PMID:17396150, GO:0000166=PMID:18172500, GO:0004520=PMID:17396150, GO:0005634=PMID:17396150, GO:0006974=PMID:17396150, GO:0046872=GO_REF:0000037, GO:0006302=PMID:17396150, GO:0005829=GO_REF:0000039} Q8IW19 Aprataxin and PNK-like factor protein 20090814 {GO:0003906=IDA, GO:0005515=IPI, GO:0000012=IMP, GO:0008408=IDA, GO:0000166=IDA, GO:0004520=IDA, GO:0005634=IDA, GO:0006974=IDA, GO:0046872=IEA, GO:0006302=IMP, GO:0005829=IEA} double-strand break repair, response to DNA damage stimulus, single strand break repair cytosol, nucleus 3'-5' exonuclease activity, DNA-(apurinic or apyrimidinic site) lyase activity, endodeoxyribonuclease activity, metal ion binding, nucleotide binding, protein binding Human UniProtKB:P09874 APLN Reactome UniProtKB {GO:0048471=GO_REF:0000019, GO:0008284=GO_REF:0000019, GO:0005102=PMID:9792798, GO:0005576=Reactome:REACT_22289, GO:0045776=GO_REF:0000019, GO:0005615=GO_REF:0000019, GO:0031704=GO_REF:0000019, GO:0007165=GO_REF:0000002, GO:0006955=PMID:10525157, GO:0043576=GO_REF:0000019, GO:0007595=PMID:10525157, GO:0005179=GO_REF:0000037, GO:0042756=GO_REF:0000019, GO:0045906=GO_REF:0000019, GO:0002026=GO_REF:0000019, GO:0045909=GO_REF:0000019, GO:0051461=GO_REF:0000019, GO:0031652=GO_REF:0000019, GO:0051466=GO_REF:0000019, GO:0042327=GO_REF:0000019} Q9ULZ1 Apelin protein 20080729 {GO:0048471=IEA, GO:0008284=IEA, GO:0005102=TAS, GO:0005576=TAS, GO:0045776=IEA, GO:0005615=IEA, GO:0031704=IEA, GO:0007165=IEA, GO:0006955=TAS, GO:0043576=IEA, GO:0007595=TAS, GO:0005179=IEA, GO:0042756=IEA, GO:0045906=IEA, GO:0002026=IEA, GO:0045909=IEA, GO:0051461=IEA, GO:0031652=IEA, GO:0051466=IEA, GO:0042327=IEA} drinking behavior, immune response, lactation, negative regulation of blood pressure, negative regulation of vasoconstriction, positive regulation of cell proliferation, positive regulation of corticotropin secretion, positive regulation of corticotropin-releasing hormone secretion, positive regulation of heat generation, positive regulation of phosphorylation, positive regulation of vasodilation, regulation of respiratory gaseous exchange, regulation of the force of heart contraction, signal transduction extracellular region, extracellular space, perinuclear region of cytoplasm apelin receptor binding, hormone activity, receptor binding Human APLNR Reactome UniProtKB {GO:0005886=Reactome:REACT_22289, GO:0007186=PMID:9792798, GO:0005887=PMID:8294032, GO:0004930=GO_REF:0000037, GO:0004872=PMID:9792798, GO:0050878=GO_REF:0000019} P35414 Apelin receptor protein 20080728 {GO:0005886=TAS, GO:0007186=TAS, GO:0005887=TAS, GO:0004930=IEA, GO:0004872=TAS, GO:0050878=IEA} G-protein coupled receptor signaling pathway, regulation of body fluid levels integral to plasma membrane, plasma membrane G-protein coupled receptor activity, receptor activity Human APLP1 BHF-UCL UniProtKB {GO:0005515=PMID:16193067, GO:0006378=GO_REF:0000019, GO:0048471=PMID:16531006, GO:0005794=GO_REF:0000019, GO:0005886=PMID:16531006, GO:0030818=PMID:16531006, GO:0046914=GO_REF:0000002, GO:0006915=GO_REF:0000037, GO:0031696=PMID:16531006, GO:0007193=PMID:16531006, GO:0031695=PMID:16531006, GO:0031694=PMID:16531006, GO:0006417=GO_REF:0000019, GO:0005604=PMID:9521588, GO:0006897=GO_REF:0000037, GO:0007399=PMID:9521588, GO:0042802=PMID:16193067, GO:0030198=GO_REF:0000019, GO:0009887=PMID:9521588, GO:0071874=PMID:16531006, GO:0016021=GO_REF:0000037, GO:0030900=GO_REF:0000019, GO:0007155=GO_REF:0000037, GO:0008201=GO_REF:0000037} P51693 Amyloid-like protein 1 protein 20110110 {GO:0005515=IPI, GO:0006378=IEA, GO:0048471=IDA, GO:0005794=IEA, GO:0005886=IDA, GO:0030818=IDA, GO:0046914=IEA, GO:0006915=IEA, GO:0031696=IPI, GO:0007193=IC, GO:0031695=IPI, GO:0031694=IPI, GO:0006417=IEA, GO:0005604=TAS, GO:0006897=IEA, GO:0007399=TAS, GO:0042802=IPI, GO:0030198=IEA, GO:0009887=TAS, GO:0071874=IDA, GO:0016021=IEA, GO:0030900=IEA, GO:0007155=IEA, GO:0008201=IEA} adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway, apoptotic process, cell adhesion, cellular response to norepinephrine stimulus, endocytosis, extracellular matrix organization, forebrain development, mRNA polyadenylation, negative regulation of cAMP biosynthetic process, nervous system development, organ morphogenesis, regulation of translation Golgi apparatus, basement membrane, integral to membrane, perinuclear region of cytoplasm, plasma membrane alpha-2A adrenergic receptor binding, alpha-2B adrenergic receptor binding, alpha-2C adrenergic receptor binding, heparin binding, identical protein binding, protein binding, transition metal ion binding Human APLP2 ENSEMBL UniProtKB {GO:0005515=PMID:20936779, GO:0005886=GO_REF:0000039, GO:0004867=GO_REF:0000037, GO:0007617=GO_REF:0000019, GO:0046914=GO_REF:0000002, GO:0043393=GO_REF:0000019, GO:0005634=PMID:7702756, GO:0009790=GO_REF:0000019, GO:0003677=PMID:7702756, GO:0042802=PMID:16193067, GO:0001967=GO_REF:0000019, GO:0006878=GO_REF:0000019, GO:0007186=PMID:8220435, GO:0030198=GO_REF:0000019, GO:0007176=GO_REF:0000019, GO:0050885=GO_REF:0000019, GO:0007626=GO_REF:0000019, GO:0030901=GO_REF:0000019, GO:0016021=PMID:8485127, GO:0030900=GO_REF:0000019, GO:0008201=GO_REF:0000002, GO:0008203=GO_REF:0000019} Q9UED0 Amyloid-like protein 2 protein 20130413 {GO:0005515=IPI, GO:0005886=IEA, GO:0004867=IEA, GO:0007617=IEA, GO:0046914=IEA, GO:0043393=IEA, GO:0005634=IDA, GO:0009790=IEA, GO:0003677=NAS, GO:0042802=IPI, GO:0001967=IEA, GO:0006878=IEA, GO:0007186=NAS, GO:0030198=IEA, GO:0007176=IEA, GO:0050885=IEA, GO:0007626=IEA, GO:0030901=IEA, GO:0016021=NAS, GO:0030900=IEA, GO:0008201=IEA, GO:0008203=IEA} G-protein coupled receptor signaling pathway, cellular copper ion homeostasis, cholesterol metabolic process, embryo development, extracellular matrix organization, forebrain development, locomotory behavior, mating behavior, midbrain development, neuromuscular process controlling balance, regulation of epidermal growth factor-activated receptor activity, regulation of protein binding, suckling behavior integral to membrane, nucleus, plasma membrane DNA binding, heparin binding, identical protein binding, protein binding, serine-type endopeptidase inhibitor activity, transition metal ion binding Human Ensembl:ENSMUSP00000072428 APOA1 BHF-UCL UniProtKB {GO:0005515=PMID:12084722, GO:0006695=GO_REF:0000019, GO:0043627=GO_REF:0000019, GO:0007603=Reactome:REACT_160125, GO:0019915=GO_REF:0000019, GO:0060192=GO_REF:0000019, GO:0030300=GO_REF:0000019, GO:0018206=PMID:12576517, GO:0010903=PMID:14967812, GO:0030301=PMID:10559507, GO:0005615=PMID:22261194, GO:0042802=PMID:8049247, GO:0034361=PMID:17154273, GO:0034364=PMID:21571275, GO:0034115=PMID:21571275, GO:0055102=GO_REF:0000019, GO:0044255=Reactome:REACT_22279, GO:0006656=PMID:4335615, GO:0042632=PMID:21571275, GO:0033344=PMID:11162594, GO:0060761=PMID:21571275, GO:0051345=PMID:7638166, GO:0043691=PMID:15464323, GO:0034366=PMID:16682745, GO:0030168=Reactome:REACT_798, GO:0051347=GO_REF:0000019, GO:0005548=GO_REF:0000019, GO:0010804=PMID:21571275, GO:0070508=PMID:14718538, GO:0043534=GO_REF:0000019, GO:0007186=PMID:16443932, GO:0034375=PMID:4335615, GO:0042157=Reactome:REACT_13621, GO:0055091=PMID:21571275, GO:0005788=Reactome:REACT_6915, GO:0019899=PMID:1587806, GO:0034774=Reactome:REACT_21324, GO:0042158=GO_REF:0000019, GO:0008035=GO_REF:0000019, GO:0006629=Reactome:REACT_602, GO:0030325=GO_REF:0000019, GO:0005886=Reactome:REACT_15367, GO:0031100=GO_REF:0000019, GO:0017127=PMID:9651324, GO:0010873=PMID:4335615, GO:0070328=PMID:21571275, GO:0050713=PMID:12458630, GO:0030139=PMID:14747463, GO:0005634=GO_REF:0000019, GO:0044281=Reactome:REACT_111217, GO:0060228=PMID:4335615, GO:0005829=Reactome:REACT_160215, GO:0008289=GO_REF:0000002, GO:0002740=PMID:12458630, GO:0034384=PMID:12651854, GO:0005543=PMID:12810715, GO:0001540=PMID:11297421, GO:0034191=PMID:16443932, GO:0015485=PMID:15464323, GO:0014012=GO_REF:0000019, GO:0034190=PMID:11162594, GO:0034380=PMID:190223, GO:0018158=PMID:12576517, GO:0070653=PMID:10764676, GO:0008203=PMID:15464323, GO:0032489=PMID:16443932, GO:0007584=GO_REF:0000019, GO:0042493=GO_REF:0000019, GO:0050821=PMID:17655203, GO:0005576=Reactome:REACT_160272, GO:0031410=PMID:14703508, GO:0001523=Reactome:REACT_24968, GO:0055085=Reactome:REACT_15518, GO:0033700=PMID:11162594, GO:0007596=Reactome:REACT_604, GO:0050728=PMID:21571275, GO:0001935=GO_REF:0000019, GO:0002576=Reactome:REACT_318, GO:0006869=GO_REF:0000038, GO:0001932=GO_REF:0000019, GO:0008211=GO_REF:0000019, GO:0005769=Reactome:REACT_160272} P02647 Apolipoprotein A-I protein 20120601 {GO:0005515=IPI, GO:0006695=IEA, GO:0043627=IEA, GO:0007603=TAS, GO:0019915=IEA, GO:0060192=IEA, GO:0030300=IEA, GO:0018206=IDA, GO:0010903=IDA, GO:0030301=IDA, GO:0005615=ISS, GO:0042802=IPI, GO:0034361=IDA, GO:0034364=IDA, GO:0034115=IDA, GO:0055102=IEA, GO:0044255=TAS, GO:0006656=IDA, GO:0042632=IDA, GO:0033344=IDA, GO:0060761=IDA, GO:0051345=IDA, GO:0043691=IMP, GO:0034366=IDA, GO:0030168=TAS, GO:0051347=IEA, GO:0005548=IEA, GO:0010804=IDA, GO:0070508=IMP, GO:0043534=IEA, GO:0007186=IDA, GO:0034375=IC, GO:0042157=TAS, GO:0055091=IDA, GO:0005788=TAS, GO:0019899=IPI, GO:0034774=TAS, GO:0042158=IEA, GO:0008035=IEA, GO:0006629=TAS, GO:0030325=IEA, GO:0005886=TAS, GO:0031100=IEA, GO:0017127=IDA, GO:0010873=IDA, GO:0070328=IDA, GO:0050713=IDA, GO:0030139=IDA, GO:0005634=IEA, GO:0044281=TAS, GO:0060228=IDA, GO:0005829=TAS, GO:0008289=IEA, GO:0002740=IDA, GO:0034384=IC, GO:0005543=IDA, GO:0001540=IDA, GO:0034191=IPI, GO:0015485=IDA, GO:0014012=IEA, GO:0034190=IPI, GO:0034380=IDA, GO:0018158=IDA, GO:0070653=IPI, GO:0008203=IMP, GO:0032489=IDA, GO:0007584=IEA, GO:0042493=IEA, GO:0050821=IDA, GO:0005576=TAS, GO:0031410=IDA, GO:0001523=TAS, GO:0055085=TAS, GO:0033700=IDA, GO:0007596=TAS, GO:0050728=IDA, GO:0001935=IEA, GO:0002576=TAS, GO:0006869=IEA, GO:0001932=IEA, GO:0008211=IEA, GO:0005769=TAS} G-protein coupled receptor signaling pathway, adrenal gland development, blood coagulation, blood vessel endothelial cell migration, cellular lipid metabolic process, cholesterol biosynthetic process, cholesterol efflux, cholesterol homeostasis, cholesterol import, cholesterol metabolic process, cholesterol transport, endothelial cell proliferation, glucocorticoid metabolic process, high-density lipoprotein particle assembly, high-density lipoprotein particle clearance, high-density lipoprotein particle remodeling, lipid metabolic process, lipid storage, lipid transport, lipoprotein biosynthetic process, lipoprotein metabolic process, negative regulation of cytokine secretion involved in immune response, negative regulation of heterotypic cell-cell adhesion, negative regulation of inflammatory response, negative regulation of interleukin-1 beta secretion, negative regulation of lipase activity, negative regulation of response to cytokine stimulus, negative regulation of tumor necrosis factor-mediated signaling pathway, negative regulation of very-low-density lipoprotein particle remodeling, organ regeneration, peptidyl-methionine modification, peripheral nervous system axon regeneration, phosphatidylcholine biosynthetic process, phospholipid efflux, phospholipid homeostasis, phototransduction, visible light, platelet activation, platelet degranulation, positive regulation of cholesterol esterification, positive regulation of hydrolase activity, positive regulation of transferase activity, protein oxidation, protein stabilization, regulation of Cdc42 protein signal transduction, regulation of intestinal cholesterol absorption, regulation of protein phosphorylation, response to drug, response to estrogen stimulus, response to nutrient, retinoid metabolic process, reverse cholesterol transport, small molecule metabolic process, transmembrane transport, triglyceride homeostasis cytoplasmic vesicle, cytosol, early endosome, endocytic vesicle, endoplasmic reticulum lumen, extracellular region, extracellular space, high-density lipoprotein particle, nucleus, plasma membrane, secretory granule lumen, spherical high-density lipoprotein particle, very-low-density lipoprotein particle apolipoprotein A-I receptor binding, apolipoprotein receptor binding, beta-amyloid binding, cholesterol binding, cholesterol transporter activity, enzyme binding, high-density lipoprotein particle binding, high-density lipoprotein particle receptor binding, identical protein binding, lipase inhibitor activity, lipid binding, phosphatidylcholine-sterol O-acyltransferase activator activity, phospholipid binding, phospholipid transporter activity, protein binding Human APOA1BP BHF-UCL UniProtKB {GO:0005515=PMID:11991719, GO:0005739=GO_REF:0000039, GO:0008150=GO_REF:0000015, GO:0000166=GO_REF:0000037, GO:0051289=GO_REF:0000019, GO:0005576=PMID:11991719, GO:0005615=PMID:22261194, GO:0044297=GO_REF:0000019, GO:0042803=GO_REF:0000019, GO:0052856=GO_REF:0000020, GO:0046872=GO_REF:0000037} Q8NCW5 NAD(P)H-hydrate epimerase protein 20120228 {GO:0005515=IPI, GO:0005739=IEA, GO:0008150=ND, GO:0000166=IEA, GO:0051289=IEA, GO:0005576=IDA, GO:0005615=ISS, GO:0044297=IEA, GO:0042803=IEA, GO:0052856=IEA, GO:0046872=IEA} biological_process, protein homotetramerization cell body, extracellular region, extracellular space, mitochondrion NADHX epimerase activity, metal ion binding, nucleotide binding, protein binding, protein homodimerization activity Human UniProtKB:Q0PIT9 APOA2 BHF-UCL UniProtKB {GO:0005515=PMID:17786215, GO:0043627=GO_REF:0000019, GO:0007603=Reactome:REACT_160125, GO:0060192=PMID:14967812, GO:0018206=PMID:12576517, GO:0030300=GO_REF:0000019, GO:0010903=PMID:14967812, GO:0042803=PMID:17264082, GO:0034361=PMID:8245722, GO:0034364=PMID:17264082, GO:0006457=PMID:14967812, GO:0055102=PMID:14967812, GO:0044255=Reactome:REACT_22279, GO:0006656=PMID:14967812, GO:0042632=PMID:14967812, GO:0033344=PMID:11162594, GO:0002526=GO_REF:0000019, GO:0046982=PMID:8245722, GO:0043691=PMID:14967812, GO:0045416=PMID:11591715, GO:0034366=PMID:16682745, GO:0051384=GO_REF:0000019, GO:0034370=PMID:14967812, GO:0034374=PMID:8106353, GO:0034375=PMID:14967812, GO:0042157=Reactome:REACT_6841, GO:0005788=Reactome:REACT_6915, GO:0006641=PMID:11551871, GO:0005319=PMID:1606170, GO:0006629=Reactome:REACT_602, GO:0008035=GO_REF:0000019, GO:0032375=PMID:8636092, GO:0050996=PMID:8640403, GO:0050995=PMID:14967812, GO:0060695=PMID:8106353, GO:0031100=GO_REF:0000019, GO:0017127=PMID:9651324, GO:0042627=PMID:8245722, GO:0010873=PMID:14967812, GO:0044281=Reactome:REACT_111217, GO:0005829=Reactome:REACT_160215, GO:0002740=PMID:12458630, GO:0060228=PMID:14967812, GO:0008289=PMID:14967812, GO:0031647=PMID:14967812, GO:0005543=PMID:218942, GO:0034384=PMID:10764676, GO:0015485=PMID:218942, GO:0018158=PMID:12576517, GO:0034380=PMID:218942, GO:0034190=PMID:11162594, GO:0070653=PMID:10764676, GO:0060621=PMID:10764676, GO:0008203=GO_REF:0000019, GO:0046340=PMID:14967812, GO:0042493=GO_REF:0000019, GO:0031210=PMID:17264082, GO:0005576=Reactome:REACT_160272, GO:0001523=Reactome:REACT_24968, GO:0009749=PMID:14988251, GO:0033700=PMID:11162594, GO:0019048=GO_REF:0000037, GO:0009395=PMID:14967812, GO:0005769=Reactome:REACT_160272} P02652 Apolipoprotein A-II protein 20080402 {GO:0005515=IPI, GO:0043627=IEA, GO:0007603=TAS, GO:0060192=IDA, GO:0018206=IDA, GO:0030300=IEA, GO:0010903=IDA, GO:0042803=IDA, GO:0034361=IDA, GO:0034364=IDA, GO:0006457=IDA, GO:0055102=IDA, GO:0044255=TAS, GO:0006656=IDA, GO:0042632=IDA, GO:0033344=IDA, GO:0002526=IEA, GO:0046982=IPI, GO:0043691=IDA, GO:0045416=IDA, GO:0034366=IDA, GO:0051384=IEA, GO:0034370=IDA, GO:0034374=IDA, GO:0034375=IDA, GO:0042157=TAS, GO:0005788=TAS, GO:0006641=TAS, GO:0005319=IDA, GO:0006629=TAS, GO:0008035=IEA, GO:0032375=IMP, GO:0050996=IDA, GO:0050995=IDA, GO:0060695=IDA, GO:0031100=IEA, GO:0017127=IDA, GO:0042627=IDA, GO:0010873=IDA, GO:0044281=TAS, GO:0005829=TAS, GO:0002740=IDA, GO:0060228=IDA, GO:0008289=IDA, GO:0031647=IDA, GO:0005543=IDA, GO:0034384=IDA, GO:0015485=IDA, GO:0018158=IDA, GO:0034380=IDA, GO:0034190=IPI, GO:0070653=IPI, GO:0060621=IDA, GO:0008203=IEA, GO:0046340=IDA, GO:0042493=IEA, GO:0031210=IDA, GO:0005576=TAS, GO:0001523=TAS, GO:0009749=IDA, GO:0033700=IDA, GO:0019048=IEA, GO:0009395=IDA, GO:0005769=TAS} acute inflammatory response, cellular lipid metabolic process, cholesterol efflux, cholesterol homeostasis, cholesterol metabolic process, diacylglycerol catabolic process, high-density lipoprotein particle assembly, high-density lipoprotein particle clearance, high-density lipoprotein particle remodeling, lipid metabolic process, lipoprotein metabolic process, low-density lipoprotein particle remodeling, negative regulation of cholesterol import, negative regulation of cholesterol transport, negative regulation of cholesterol transporter activity, negative regulation of cytokine secretion involved in immune response, negative regulation of lipase activity, negative regulation of lipid catabolic process, negative regulation of very-low-density lipoprotein particle remodeling, organ regeneration, peptidyl-methionine modification, phosphatidylcholine biosynthetic process, phospholipid catabolic process, phospholipid efflux, phototransduction, visible light, positive regulation of cholesterol esterification, positive regulation of interleukin-8 biosynthetic process, positive regulation of lipid catabolic process, protein folding, protein oxidation, regulation of intestinal cholesterol absorption, regulation of protein stability, response to drug, response to estrogen stimulus, response to glucocorticoid stimulus, response to glucose stimulus, retinoid metabolic process, reverse cholesterol transport, small molecule metabolic process, triglyceride metabolic process, triglyceride-rich lipoprotein particle remodeling, virus-host interaction chylomicron, cytosol, early endosome, endoplasmic reticulum lumen, extracellular region, high-density lipoprotein particle, spherical high-density lipoprotein particle, very-low-density lipoprotein particle apolipoprotein receptor binding, cholesterol binding, cholesterol transporter activity, high-density lipoprotein particle binding, high-density lipoprotein particle receptor binding, lipase inhibitor activity, lipid binding, lipid transporter activity, phosphatidylcholine binding, phosphatidylcholine-sterol O-acyltransferase activator activity, phospholipid binding, protein binding, protein heterodimerization activity, protein homodimerization activity Human APOA4 BHF-UCL UniProtKB {GO:0035634=GO_REF:0000019, GO:0043499=PMID:1935934, GO:0007603=Reactome:REACT_160125, GO:0006982=PMID:16945374, GO:0010898=PMID:2307668, GO:0030300=GO_REF:0000019, GO:0005615=PMID:1935934, GO:0042803=PMID:1935934, GO:0034361=PMID:3095477, GO:0034364=PMID:3095477, GO:0019430=PMID:16945374, GO:0034445=PMID:16945374, GO:0042744=PMID:16945374, GO:0042632=PMID:1935934, GO:0033344=PMID:11162594, GO:0016209=PMID:16945374, GO:0032374=PMID:11940599, GO:0009986=PMID:1935934, GO:0005507=PMID:16945374, GO:0043691=PMID:3095477, GO:0065005=PMID:16159879, GO:0002227=PMID:15254593, GO:0034372=PMID:2307668, GO:0034371=PMID:2307668, GO:0034375=PMID:1935934, GO:0042157=Reactome:REACT_6841, GO:0005788=Reactome:REACT_6915, GO:0005319=PMID:3080432, GO:0051006=PMID:2307668, GO:0006629=Reactome:REACT_602, GO:0017127=PMID:1935934, GO:0044240=PMID:3095477, GO:0010873=PMID:1935934, GO:0042627=PMID:3095477, GO:0044281=Reactome:REACT_111217, GO:0034378=PMID:16159879, GO:0005829=Reactome:REACT_160215, GO:0008289=PMID:16159879, GO:0060228=PMID:1935934, GO:0007159=PMID:15254593, GO:0008203=PMID:1935934, GO:0045723=PMID:2307668, GO:0055088=PMID:3095477, GO:0031210=PMID:1935934, GO:0005576=Reactome:REACT_160272, GO:0001523=Reactome:REACT_24968, GO:0033700=PMID:11162594, GO:0006869=PMID:1935934, GO:0046470=PMID:1935934, GO:0005769=Reactome:REACT_160272} P06727 Apolipoprotein A-IV protein 20100511 {GO:0035634=IEA, GO:0043499=IDA, GO:0007603=TAS, GO:0006982=IDA, GO:0010898=IDA, GO:0030300=IEA, GO:0005615=IDA, GO:0042803=IDA, GO:0034361=IDA, GO:0034364=IDA, GO:0019430=IDA, GO:0034445=IDA, GO:0042744=IDA, GO:0042632=IDA, GO:0033344=IDA, GO:0016209=IDA, GO:0032374=IDA, GO:0009986=IDA, GO:0005507=IDA, GO:0043691=IDA, GO:0065005=IMP, GO:0002227=IDA, GO:0034372=IDA, GO:0034371=IC, GO:0034375=IC, GO:0042157=TAS, GO:0005788=TAS, GO:0005319=TAS, GO:0051006=IDA, GO:0006629=TAS, GO:0017127=IDA, GO:0044240=IDA, GO:0010873=IDA, GO:0042627=IDA, GO:0044281=TAS, GO:0034378=TAS, GO:0005829=TAS, GO:0008289=IMP, GO:0060228=IDA, GO:0007159=IDA, GO:0008203=IDA, GO:0045723=IDA, GO:0055088=IDA, GO:0031210=IDA, GO:0005576=TAS, GO:0001523=TAS, GO:0033700=IDA, GO:0006869=IDA, GO:0046470=IDA, GO:0005769=TAS} cholesterol efflux, cholesterol homeostasis, cholesterol metabolic process, chylomicron assembly, chylomicron remodeling, high-density lipoprotein particle remodeling, hydrogen peroxide catabolic process, innate immune response in mucosa, leukocyte cell-cell adhesion, lipid homeostasis, lipid metabolic process, lipid transport, lipoprotein metabolic process, multicellular organismal lipid catabolic process, negative regulation of plasma lipoprotein particle oxidation, phosphatidylcholine metabolic process, phospholipid efflux, phototransduction, visible light, positive regulation of cholesterol esterification, positive regulation of fatty acid biosynthetic process, positive regulation of lipoprotein lipase activity, positive regulation of triglyceride catabolic process, protein-lipid complex assembly, regulation of cholesterol transport, regulation of intestinal cholesterol absorption, removal of superoxide radicals, response to lipid hydroperoxide, response to stilbenoid, retinoid metabolic process, reverse cholesterol transport, small molecule metabolic process, very-low-density lipoprotein particle remodeling cell surface, chylomicron, cytosol, early endosome, endoplasmic reticulum lumen, extracellular region, extracellular space, high-density lipoprotein particle, very-low-density lipoprotein particle antioxidant activity, cholesterol transporter activity, copper ion binding, eukaryotic cell surface binding, lipid binding, lipid transporter activity, phosphatidylcholine binding, phosphatidylcholine-sterol O-acyltransferase activator activity, protein homodimerization activity colocalizes_with Human APOA5 BHF-UCL UniProtKB {GO:0005515=PMID:17997385, GO:0050996=PMID:16806135, GO:0031100=GO_REF:0000019, GO:0042627=PMID:15528295, GO:0070328=PMID:19121291, GO:0010898=PMID:18635818, GO:0010902=PMID:18635818, GO:0044281=Reactome:REACT_111217, GO:0042246=PMID:11577099, GO:0070325=PMID:18635818, GO:0005615=PMID:19121291, GO:0060229=PMID:15178420, GO:0008289=PMID:12810715, GO:0034361=PMID:15528295, GO:0005543=PMID:12810715, GO:0034364=PMID:15528295, GO:0034362=PMID:15528295, GO:0019433=PMID:15178420, GO:0009725=GO_REF:0000019, GO:0008201=PMID:17326667, GO:0044255=Reactome:REACT_22279, GO:0042632=PMID:19121291, GO:0045723=PMID:18635818, GO:0031210=PMID:16806135, GO:0005576=Reactome:REACT_115631, GO:0060230=PMID:18635818, GO:0034370=GO_REF:0000019, GO:0006869=PMID:15178420, GO:0048260=PMID:18635818, GO:0042157=GO_REF:0000002, GO:0006641=PMID:11588264, GO:0055090=PMID:11588264, GO:0035473=PMID:15178420, GO:0008047=PMID:16806135, GO:0019899=PMID:15178420, GO:0050750=PMID:17326667, GO:0051006=PMID:16806135} Q6Q788 Apolipoprotein A-V protein 20121031 {GO:0005515=IPI, GO:0050996=IDA, GO:0031100=IEA, GO:0042627=IDA, GO:0070328=IDA, GO:0010898=IDA, GO:0010902=IDA, GO:0044281=TAS, GO:0042246=IEP, GO:0070325=IPI, GO:0005615=IDA, GO:0060229=IMP, GO:0008289=IDA, GO:0034361=IDA, GO:0005543=IDA, GO:0034364=IDA, GO:0034362=IDA, GO:0019433=IMP, GO:0009725=IEA, GO:0008201=IDA, GO:0044255=TAS, GO:0042632=IDA, GO:0045723=IDA, GO:0031210=IDA, GO:0005576=TAS, GO:0060230=IDA, GO:0034370=IEA, GO:0006869=IDA, GO:0048260=TAS, GO:0042157=IEA, GO:0006641=IDA, GO:0055090=IDA, GO:0035473=IPI, GO:0008047=IDA, GO:0019899=IDA, GO:0050750=IPI, GO:0051006=IDA} acylglycerol homeostasis, cellular lipid metabolic process, cholesterol homeostasis, lipid transport, lipoprotein metabolic process, organ regeneration, positive regulation of fatty acid biosynthetic process, positive regulation of lipid catabolic process, positive regulation of lipoprotein lipase activity, positive regulation of receptor-mediated endocytosis, positive regulation of triglyceride catabolic process, positive regulation of very-low-density lipoprotein particle remodeling, response to hormone stimulus, small molecule metabolic process, tissue regeneration, triglyceride catabolic process, triglyceride homeostasis, triglyceride metabolic process, triglyceride-rich lipoprotein particle remodeling chylomicron, extracellular region, extracellular space, high-density lipoprotein particle, low-density lipoprotein particle, very-low-density lipoprotein particle enzyme activator activity, enzyme binding, heparin binding, lipase activator activity, lipase binding, lipid binding, lipoprotein lipase activator activity, lipoprotein particle receptor binding, low-density lipoprotein particle receptor binding, phosphatidylcholine binding, phospholipid binding, protein binding Human UniProtKB:P06858 APOB BHF-UCL UniProtKB {GO:0005515=PMID:22580899, GO:0007603=Reactome:REACT_160125, GO:0048844=GO_REF:0000019, GO:0030301=PMID:2563166, GO:0007283=GO_REF:0000019, GO:0009791=GO_REF:0000019, GO:0050900=Reactome:REACT_12051, GO:0005615=PMID:22261194, GO:0034359=PMID:4363408, GO:0043231=PMID:7853698, GO:0034361=PMID:15308631, GO:0034360=PMID:6099394, GO:0042953=GO_REF:0000019, GO:0009743=GO_REF:0000019, GO:0034363=PMID:1917954, GO:0034362=PMID:4363408, GO:0071356=GO_REF:0000019, GO:0032496=GO_REF:0000019, GO:0019433=GO_REF:0000019, GO:0042632=PMID:2563166, GO:0033344=GO_REF:0000019, GO:0046982=PMID:8245722, GO:0010744=PMID:17244792, GO:0001701=GO_REF:0000019, GO:0006898=Reactome:REACT_6934, GO:0009566=GO_REF:0000019, GO:0034374=PMID:15797858, GO:0005789=Reactome:REACT_6908, GO:0042157=Reactome:REACT_6841, GO:0005788=Reactome:REACT_6915, GO:0019899=PMID:9685400, GO:0006642=GO_REF:0000019, GO:0005319=GO_REF:0000002, GO:0042159=GO_REF:0000019, GO:0010008=Reactome:REACT_6901, GO:0042158=GO_REF:0000019, GO:0006629=Reactome:REACT_602, GO:0005886=Reactome:REACT_6940, GO:0017127=PMID:15797858, GO:0045540=GO_REF:0000019, GO:0042627=PMID:8245722, GO:0044281=Reactome:REACT_111217, GO:0034379=PMID:15308631, GO:0005829=Reactome:REACT_160215, GO:0005737=PMID:22580899, GO:0005543=PMID:7126555, GO:0034383=PMID:2563166, GO:0071379=GO_REF:0000019, GO:0008201=PMID:16233946, GO:0008203=PMID:2563166, GO:0010269=GO_REF:0000019, GO:0005576=Reactome:REACT_160272, GO:0010884=PMID:18322245, GO:0031983=GO_REF:0000019, GO:0030317=GO_REF:0000019, GO:0009615=PMID:16548883, GO:0010886=PMID:19114110, GO:0001523=Reactome:REACT_24968, GO:0007399=GO_REF:0000019, GO:0031904=Reactome:REACT_6775, GO:0007596=Reactome:REACT_604, GO:0030669=Reactome:REACT_6924, GO:0005769=Reactome:REACT_160272, GO:0050750=PMID:15797858} P04114 Apolipoprotein B-100 protein 20080423 {GO:0005515=IPI, GO:0007603=TAS, GO:0048844=IEA, GO:0030301=IMP, GO:0007283=IEA, GO:0009791=IEA, GO:0050900=TAS, GO:0005615=ISS, GO:0034359=IDA, GO:0043231=TAS, GO:0034361=IDA, GO:0034360=TAS, GO:0042953=IEA, GO:0009743=IEA, GO:0034363=IDA, GO:0034362=IDA, GO:0071356=IEA, GO:0032496=IEA, GO:0019433=IEA, GO:0042632=IMP, GO:0033344=IEA, GO:0046982=IPI, GO:0010744=IDA, GO:0001701=IEA, GO:0006898=TAS, GO:0009566=IEA, GO:0034374=IMP, GO:0005789=TAS, GO:0042157=TAS, GO:0005788=TAS, GO:0019899=IPI, GO:0006642=IEA, GO:0005319=IEA, GO:0042159=IEA, GO:0010008=TAS, GO:0042158=IEA, GO:0006629=TAS, GO:0005886=TAS, GO:0017127=IMP, GO:0045540=IEA, GO:0042627=IDA, GO:0044281=TAS, GO:0034379=IC, GO:0005829=TAS, GO:0005737=IDA, GO:0005543=IDA, GO:0034383=IMP, GO:0071379=IEA, GO:0008201=IDA, GO:0008203=IMP, GO:0010269=IEA, GO:0005576=TAS, GO:0010884=IDA, GO:0031983=IEA, GO:0030317=IEA, GO:0009615=IEP, GO:0010886=IDA, GO:0001523=TAS, GO:0007399=IEA, GO:0031904=TAS, GO:0007596=TAS, GO:0030669=TAS, GO:0005769=TAS, GO:0050750=IMP} artery morphogenesis, blood coagulation, cellular response to prostaglandin stimulus, cellular response to tumor necrosis factor, cholesterol efflux, cholesterol homeostasis, cholesterol metabolic process, cholesterol transport, fertilization, in utero embryonic development, leukocyte migration, lipid metabolic process, lipoprotein biosynthetic process, lipoprotein catabolic process, lipoprotein metabolic process, lipoprotein transport, low-density lipoprotein particle clearance, low-density lipoprotein particle remodeling, nervous system development, phototransduction, visible light, positive regulation of cholesterol storage, positive regulation of lipid storage, positive regulation of macrophage derived foam cell differentiation, post-embryonic development, receptor-mediated endocytosis, regulation of cholesterol biosynthetic process, response to carbohydrate stimulus, response to lipopolysaccharide, response to selenium ion, response to virus, retinoid metabolic process, small molecule metabolic process, sperm motility, spermatogenesis, triglyceride catabolic process, triglyceride mobilization, very-low-density lipoprotein particle assembly chylomicron, chylomicron remnant, clathrin-coated endocytic vesicle membrane, cytoplasm, cytosol, early endosome, endoplasmic reticulum lumen, endoplasmic reticulum membrane, endosome lumen, endosome membrane, extracellular region, extracellular space, intermediate-density lipoprotein particle, intracellular membrane-bounded organelle, low-density lipoprotein particle, mature chylomicron, plasma membrane, very-low-density lipoprotein particle, vesicle lumen cholesterol transporter activity, enzyme binding, heparin binding, lipid transporter activity, low-density lipoprotein particle receptor binding, phospholipid binding, protein binding, protein heterodimerization activity Human APOBEC1 GOC UniProtKB {GO:0005515=PMID:10669759, GO:0006629=PMID:8078915, GO:0010467=Reactome:REACT_71, GO:0009972=PMID:7736571, GO:0045471=GO_REF:0000019, GO:0003723=PMID:7736571, GO:0010043=GO_REF:0000019, GO:0005737=PMID:22580899, GO:0042953=GO_REF:0000019, GO:0051607=GO_REF:0000019, GO:0042127=GO_REF:0000019, GO:0080111=GO_REF:0000024, GO:0017091=GO_REF:0000019, GO:0004126=PMID:7736571, GO:0048255=GO_REF:0000019, GO:0010332=GO_REF:0000019, GO:0006397=GO_REF:0000037, GO:0006396=PMID:7736571, GO:0032869=GO_REF:0000019, GO:0016556=Reactome:REACT_1757, GO:0042493=GO_REF:0000019, GO:0016554=Reactome:REACT_167, GO:0006970=GO_REF:0000019, GO:0090310=GO_REF:0000024, GO:0051592=GO_REF:0000019, GO:0008270=GO_REF:0000002, GO:0005654=Reactome:REACT_869, GO:0042158=GO_REF:0000019} P41238 C->U-editing enzyme APOBEC-1 protein 20130413 {GO:0005515=IPI, GO:0006629=TAS, GO:0010467=TAS, GO:0009972=TAS, GO:0045471=IEA, GO:0003723=TAS, GO:0010043=IEA, GO:0005737=IDA, GO:0042953=IEA, GO:0051607=IEA, GO:0042127=IEA, GO:0080111=ISS, GO:0017091=IEA, GO:0004126=TAS, GO:0048255=IEA, GO:0010332=IEA, GO:0006397=IEA, GO:0006396=TAS, GO:0032869=IEA, GO:0016556=TAS, GO:0042493=IEA, GO:0016554=TAS, GO:0006970=IEA, GO:0090310=ISS, GO:0051592=IEA, GO:0008270=IEA, GO:0005654=TAS, GO:0042158=IEA} DNA demethylation, RNA processing, cellular response to insulin stimulus, cytidine deamination, cytidine to uridine editing, defense response to virus, gene expression, lipid metabolic process, lipoprotein biosynthetic process, lipoprotein transport, mRNA modification, mRNA processing, mRNA stabilization, negative regulation of methylation-dependent chromatin silencing, regulation of cell proliferation, response to calcium ion, response to drug, response to ethanol, response to gamma radiation, response to osmotic stress, response to zinc ion cytoplasm, nucleoplasm AU-rich element binding, RNA binding, cytidine deaminase activity, protein binding, zinc ion binding Human APOBEC2 GOC UniProtKB {GO:0006397=GO_REF:0000037, GO:0009972=PMID:10403781, GO:0016556=GO_REF:0000019, GO:0003723=PMID:10403781, GO:0080111=PMID:21496894, GO:0004126=PMID:10403781, GO:0008270=GO_REF:0000002} Q9Y235 Probable C->U-editing enzyme APOBEC-2 protein 20130413 {GO:0006397=IEA, GO:0009972=TAS, GO:0016556=IEA, GO:0003723=TAS, GO:0080111=IDA, GO:0004126=TAS, GO:0008270=IEA} DNA demethylation, cytidine deamination, mRNA modification, mRNA processing RNA binding, cytidine deaminase activity, zinc ion binding Human APOBEC3A GOC UniProtKB {GO:0005515=PMID:22915799, GO:0009972=PMID:21123384, GO:0047844=PMID:22457529, GO:0005634=PMID:21835787, GO:0010529=PMID:20062055, GO:0071466=PMID:20062055, GO:0044356=PMID:20062055, GO:0051607=PMID:22457529, GO:0005737=PMID:21835787, GO:0045087=PMID:21123384, GO:0080111=PMID:21496894, GO:0004126=PMID:20062055, GO:0008270=GO_REF:0000002, GO:0045071=PMID:16527742, GO:0070383=PMID:21123384} P31941 DNA dC->dU-editing enzyme APOBEC-3A protein 20130413 {GO:0005515=IPI, GO:0009972=IDA, GO:0047844=IMP, GO:0005634=IDA, GO:0010529=IDA, GO:0071466=IDA, GO:0044356=IDA, GO:0051607=IDA, GO:0005737=IDA, GO:0045087=IDA, GO:0080111=IDA, GO:0004126=IMP, GO:0008270=IEA, GO:0045071=IDA, GO:0070383=IDA} DNA cytosine deamination, DNA demethylation, cellular response to xenobiotic stimulus, clearance of foreign intracellular DNA by conversion of DNA cytidine to uridine, cytidine deamination, defense response to virus, innate immune response, negative regulation of transposition, negative regulation of viral genome replication cytoplasm, nucleus cytidine deaminase activity, deoxycytidine deaminase activity, protein binding, zinc ion binding Human APOBEC3B UniProtKB UniProtKB {GO:0016814=GO_REF:0000002, GO:0051607=PMID:22915799, GO:0047844=PMID:22457529, GO:0003723=GO_REF:0000037, GO:0045087=GO_REF:0000037, GO:0005634=PMID:21835787, GO:0008270=GO_REF:0000002, GO:0010529=PMID:20062055} Q9UH17 DNA dC->dU-editing enzyme APOBEC-3B protein 20130130 {GO:0016814=IEA, GO:0051607=IDA, GO:0047844=IMP, GO:0003723=IEA, GO:0045087=IEA, GO:0005634=IDA, GO:0008270=IEA, GO:0010529=IDA} defense response to virus, innate immune response, negative regulation of transposition nucleus RNA binding, deoxycytidine deaminase activity, hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines, zinc ion binding Human APOBEC3C UniProtKB UniProtKB {GO:0005515=PMID:22915799, GO:0016814=GO_REF:0000002, GO:0005737=PMID:21835787, GO:0051607=GO_REF:0000037, GO:0009972=PMID:21632763, GO:0045087=GO_REF:0000037, GO:0019048=GO_REF:0000037, GO:0080111=PMID:21496894, GO:0005634=PMID:21835787, GO:0008270=GO_REF:0000002, GO:0010529=PMID:20062055, GO:0045071=PMID:21632763} Q9NRW3 DNA dC->dU-editing enzyme APOBEC-3C protein 20130130 {GO:0005515=IPI, GO:0016814=IEA, GO:0005737=IDA, GO:0051607=IEA, GO:0009972=IDA, GO:0045087=IEA, GO:0019048=IEA, GO:0080111=IDA, GO:0005634=IDA, GO:0008270=IEA, GO:0010529=IDA, GO:0045071=IDA} DNA demethylation, cytidine deamination, defense response to virus, innate immune response, negative regulation of transposition, negative regulation of viral genome replication, virus-host interaction cytoplasm, nucleus hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines, protein binding, zinc ion binding Human APOBEC3D UniProtKB UniProtKB {GO:0016814=GO_REF:0000002, GO:0005737=PMID:21835787, GO:0051607=PMID:21835787, GO:0000932=PMID:22915799, GO:0045087=GO_REF:0000037, GO:0045869=PMID:21835787, GO:0008270=GO_REF:0000002, GO:0010529=PMID:20062055, GO:0070383=PMID:21835787} Q96AK3 DNA dC->dU-editing enzyme APOBEC-3D protein 20130130 {GO:0016814=IEA, GO:0005737=IDA, GO:0051607=IDA, GO:0000932=IDA, GO:0045087=IEA, GO:0045869=IDA, GO:0008270=IEA, GO:0010529=IDA, GO:0070383=IDA} DNA cytosine deamination, defense response to virus, innate immune response, negative regulation of retroviral genome replication, negative regulation of transposition cytoplasm, cytoplasmic mRNA processing body hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines, zinc ion binding Human APOBEC3F GOC UniProtKB {GO:0030895=PMID:17121840, GO:0005515=PMID:22915799, GO:0009972=PMID:17121840, GO:0016553=PMID:17121840, GO:0003723=PMID:11863358, GO:0045869=PMID:17121840, GO:0048525=PMID:17121840, GO:0010529=PMID:20062055, GO:0005737=PMID:21835787, GO:0051607=PMID:22915799, GO:0000932=PMID:22915799, GO:0030529=PMID:16699599, GO:0002230=PMID:17121840, GO:0045087=PMID:17121840, GO:0080111=PMID:21496894, GO:0004126=PMID:17121840, GO:0008270=PMID:11863358, GO:0045071=PMID:17121840, GO:0070383=PMID:21835787} Q8IUX4 DNA dC->dU-editing enzyme APOBEC-3F protein 20130413 {GO:0030895=TAS, GO:0005515=IPI, GO:0009972=IDA, GO:0016553=IDA, GO:0003723=IDA, GO:0045869=IDA, GO:0048525=IDA, GO:0010529=IDA, GO:0005737=IDA, GO:0051607=IDA, GO:0000932=IDA, GO:0030529=IDA, GO:0002230=IDA, GO:0045087=IDA, GO:0080111=IDA, GO:0004126=IDA, GO:0008270=IDA, GO:0045071=IDA, GO:0070383=IDA} DNA cytosine deamination, DNA demethylation, base conversion or substitution editing, cytidine deamination, defense response to virus, innate immune response, negative regulation of retroviral genome replication, negative regulation of transposition, negative regulation of viral genome replication, negative regulation of viral reproduction, positive regulation of defense response to virus by host apolipoprotein B mRNA editing enzyme complex, cytoplasm, cytoplasmic mRNA processing body, ribonucleoprotein complex RNA binding, cytidine deaminase activity, protein binding, zinc ion binding Human APOBEC3G HPA UniProtKB {GO:0030895=PMID:17121840, GO:0005515=PMID:22915799, GO:0009972=PMID:16378963, GO:0047844=PMID:12808465, GO:0016553=PMID:17121840, GO:0003723=PMID:11863358, GO:0045869=PMID:17121840, GO:0048525=PMID:17121840, GO:0010529=PMID:16527742, GO:0042803=PMID:11863358, GO:0005829=Reactome:REACT_9471, GO:0005739=GO_REF:0000052, GO:0005737=GO_REF:0000052, GO:0051607=PMID:22915799, GO:0000932=PMID:22915799, GO:0045087=PMID:17121840, GO:0019048=GO_REF:0000037, GO:0030529=PMID:16699599, GO:0002230=PMID:17121840, GO:0016032=Reactome:REACT_6185, GO:0004126=PMID:17121840, GO:0008270=PMID:11863358, GO:0045071=PMID:17121840, GO:0070383=PMID:21835787} Q9HC16 DNA dC->dU-editing enzyme APOBEC-3G protein 20101115 {GO:0030895=TAS, GO:0005515=IPI, GO:0009972=IDA, GO:0047844=IDA, GO:0016553=TAS, GO:0003723=IDA, GO:0045869=IDA, GO:0048525=IDA, GO:0010529=IDA, GO:0042803=NAS, GO:0005829=TAS, GO:0005739=IDA, GO:0005737=IDA, GO:0051607=IDA, GO:0000932=IDA, GO:0045087=IDA, GO:0019048=IEA, GO:0030529=IDA, GO:0002230=IDA, GO:0016032=TAS, GO:0004126=TAS, GO:0008270=IDA, GO:0045071=IDA, GO:0070383=IDA} DNA cytosine deamination, base conversion or substitution editing, cytidine deamination, defense response to virus, innate immune response, negative regulation of retroviral genome replication, negative regulation of transposition, negative regulation of viral genome replication, negative regulation of viral reproduction, positive regulation of defense response to virus by host, viral reproduction, virus-host interaction apolipoprotein B mRNA editing enzyme complex, cytoplasm, cytoplasmic mRNA processing body, cytosol, mitochondrion, ribonucleoprotein complex RNA binding, cytidine deaminase activity, deoxycytidine deaminase activity, protein binding, protein homodimerization activity, zinc ion binding Human APOBEC4 UniProtKB UniProtKB {GO:0006397=GO_REF:0000037, GO:0016814=GO_REF:0000002, GO:0008270=GO_REF:0000002} Q8WW27 Putative C->U-editing enzyme APOBEC-4 protein 20130413 {GO:0006397=IEA, GO:0016814=IEA, GO:0008270=IEA} mRNA processing hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines, zinc ion binding Human UniProtKB-KW:KW-0507 APOC1 BHF-UCL UniProtKB {GO:0006629=PMID:2897845, GO:0032375=PMID:10978346, GO:0050995=PMID:15576844, GO:0005783=GO_REF:0000054, GO:0010900=PMID:2302419, GO:0010873=PMID:18992221, GO:0042627=PMID:18992221, GO:0034379=PMID:18992221, GO:0060228=PMID:18992221, GO:0034361=PMID:15576844, GO:0034364=PMID:15576844, GO:0034382=PMID:4020294, GO:0055102=PMID:15576844, GO:0034447=PMID:15576844, GO:0033344=PMID:11162594, GO:0004859=PMID:2302419, GO:0005504=PMID:17339654, GO:0032374=PMID:15576844, GO:0045717=PMID:15576844, GO:0031210=PMID:2302419, GO:0005576=GO_REF:0000002, GO:0034369=PMID:10978346, GO:0051005=PMID:15576844, GO:0010916=PMID:1917954, GO:0033700=PMID:11162594, GO:0048261=PMID:1917954, GO:0034375=PMID:18992221, GO:0042157=GO_REF:0000002, GO:0045833=PMID:182536} P02654 Apolipoprotein C-I protein 20080402 {GO:0006629=TAS, GO:0032375=IDA, GO:0050995=IDA, GO:0005783=IDA, GO:0010900=IDA, GO:0010873=TAS, GO:0042627=TAS, GO:0034379=TAS, GO:0060228=TAS, GO:0034361=IDA, GO:0034364=IDA, GO:0034382=IDA, GO:0055102=IDA, GO:0034447=IGI, GO:0033344=IDA, GO:0004859=IDA, GO:0005504=IDA, GO:0032374=IC, GO:0045717=IDA, GO:0031210=TAS, GO:0005576=IEA, GO:0034369=IDA, GO:0051005=IDA, GO:0010916=IDA, GO:0033700=IDA, GO:0048261=IDA, GO:0034375=TAS, GO:0042157=IEA, GO:0045833=IDA} cholesterol efflux, chylomicron remnant clearance, high-density lipoprotein particle remodeling, lipid metabolic process, lipoprotein metabolic process, negative regulation of cholesterol transport, negative regulation of fatty acid biosynthetic process, negative regulation of lipid catabolic process, negative regulation of lipid metabolic process, negative regulation of lipoprotein lipase activity, negative regulation of phosphatidylcholine catabolic process, negative regulation of receptor-mediated endocytosis, negative regulation of very-low-density lipoprotein particle clearance, phospholipid efflux, plasma lipoprotein particle remodeling, positive regulation of cholesterol esterification, regulation of cholesterol transport, very-low-density lipoprotein particle assembly, very-low-density lipoprotein particle clearance chylomicron, endoplasmic reticulum, extracellular region, high-density lipoprotein particle, very-low-density lipoprotein particle fatty acid binding, lipase inhibitor activity, phosphatidylcholine binding, phosphatidylcholine-sterol O-acyltransferase activator activity, phospholipase inhibitor activity Human APOC2 ENSEMBL UniProtKB {GO:0032375=PMID:15778093, GO:0006629=GO_REF:0000002, GO:0007603=Reactome:REACT_160125, GO:0042627=GO_REF:0000002, GO:0060697=PMID:10727238, GO:0070328=PMID:17018885, GO:0010898=PMID:10727238, GO:0010902=PMID:10727238, GO:0044281=Reactome:REACT_111217, GO:0005615=PMID:10727238, GO:0042803=PMID:8245722, GO:0008289=PMID:10727238, GO:0034361=PMID:8245722, GO:0042953=GO_REF:0000019, GO:0034384=PMID:15778093, GO:0034382=PMID:4020294, GO:0043274=PMID:10727238, GO:0034363=PMID:17336988, GO:0034362=PMID:8245722, GO:0055102=PMID:182536, GO:0042632=PMID:15778093, GO:0033344=PMID:11162594, GO:0042493=GO_REF:0000019, GO:0045723=PMID:10727238, GO:0043691=PMID:15778093, GO:0034366=PMID:16682745, GO:0010518=PMID:10727238, GO:0005576=Reactome:REACT_160272, GO:0001523=Reactome:REACT_24968, GO:0060230=PMID:10727238, GO:0034370=PMID:17018885, GO:0016042=GO_REF:0000037, GO:0010916=PMID:1917954, GO:0033700=PMID:11162594, GO:0034372=PMID:15778093, GO:0034371=PMID:10727238, GO:0016004=PMID:10727238, GO:0048261=PMID:1917954, GO:0006869=GO_REF:0000002, GO:0042157=Reactome:REACT_13621, GO:0008047=GO_REF:0000002, GO:0005769=Reactome:REACT_160272, GO:0051006=PMID:15878877, GO:0045833=PMID:182536} Q6P163 APOC2 protein protein 20130413 {GO:0032375=IMP, GO:0006629=IEA, GO:0007603=TAS, GO:0042627=IEA, GO:0060697=IDA, GO:0070328=IMP, GO:0010898=IDA, GO:0010902=IC, GO:0044281=TAS, GO:0005615=IDA, GO:0042803=IMP, GO:0008289=IDA, GO:0034361=IDA, GO:0042953=IEA, GO:0034384=IMP, GO:0034382=IDA, GO:0043274=IPI, GO:0034363=IDA, GO:0034362=IDA, GO:0055102=IDA, GO:0042632=IC, GO:0033344=IDA, GO:0042493=IEA, GO:0045723=IDA, GO:0043691=IC, GO:0034366=IDA, GO:0010518=IDA, GO:0005576=TAS, GO:0001523=TAS, GO:0060230=IDA, GO:0034370=TAS, GO:0016042=IEA, GO:0010916=IDA, GO:0033700=IDA, GO:0034372=TAS, GO:0034371=IC, GO:0016004=IDA, GO:0048261=IDA, GO:0006869=IEA, GO:0042157=TAS, GO:0008047=IEA, GO:0005769=TAS, GO:0051006=IDA, GO:0045833=IDA} cholesterol efflux, cholesterol homeostasis, chylomicron remnant clearance, chylomicron remodeling, high-density lipoprotein particle clearance, lipid catabolic process, lipid metabolic process, lipid transport, lipoprotein metabolic process, lipoprotein transport, negative regulation of cholesterol transport, negative regulation of lipid metabolic process, negative regulation of receptor-mediated endocytosis, negative regulation of very-low-density lipoprotein particle clearance, phospholipid efflux, phototransduction, visible light, positive regulation of fatty acid biosynthetic process, positive regulation of lipoprotein lipase activity, positive regulation of phospholipase activity, positive regulation of phospholipid catabolic process, positive regulation of triglyceride catabolic process, positive regulation of very-low-density lipoprotein particle remodeling, response to drug, retinoid metabolic process, reverse cholesterol transport, small molecule metabolic process, triglyceride homeostasis, triglyceride-rich lipoprotein particle remodeling, very-low-density lipoprotein particle remodeling chylomicron, early endosome, extracellular region, extracellular space, intermediate-density lipoprotein particle, low-density lipoprotein particle, spherical high-density lipoprotein particle, very-low-density lipoprotein particle enzyme activator activity, lipase inhibitor activity, lipid binding, lipoprotein lipase activator activity, phospholipase activator activity, phospholipase binding, protein homodimerization activity Human Ensembl:ENSRNOP00000024800 APOC3 BHF-UCL UniProtKB {GO:0007603=Reactome:REACT_160125, GO:0010897=PMID:3973011, GO:0010903=PMID:18635818, GO:0005615=PMID:11060345, GO:0034361=PMID:17154273, GO:0042953=GO_REF:0000019, GO:0010987=PMID:15778093, GO:0034363=PMID:17336988, GO:0019433=PMID:11060345, GO:0010989=PMID:15778093, GO:0055102=PMID:3973011, GO:0042632=PMID:18767813, GO:0033344=PMID:11162594, GO:0043691=PMID:15778093, GO:0034366=PMID:17438339, GO:0051005=PMID:11060345, GO:0007186=PMID:16443932, GO:0034375=PMID:17438339, GO:0042157=Reactome:REACT_13621, GO:0006641=PMID:17142127, GO:0006642=GO_REF:0000019, GO:0045833=PMID:182536, GO:0006629=Reactome:REACT_602, GO:0050995=PMID:15576844, GO:0042627=PMID:8245722, GO:0043434=GO_REF:0000019, GO:0070328=PMID:18767813, GO:0044281=Reactome:REACT_111217, GO:0034379=PMID:18399797, GO:0008289=GO_REF:0000002, GO:0006954=GO_REF:0000019, GO:0005543=PMID:11060345, GO:0034382=PMID:4020294, GO:0015485=PMID:11162594, GO:0070653=PMID:9254056, GO:0030234=PMID:11060345, GO:0060621=PMID:15778093, GO:0008203=GO_REF:0000019, GO:0032489=PMID:16443932, GO:0007584=GO_REF:0000019, GO:0042493=GO_REF:0000019, GO:0045717=PMID:11060345, GO:0005576=Reactome:REACT_160272, GO:0001523=Reactome:REACT_24968, GO:0010916=PMID:1917954, GO:0033700=PMID:11162594, GO:0048261=PMID:1917954, GO:0006869=GO_REF:0000002, GO:0005769=Reactome:REACT_160272} P02656 Apolipoprotein C-III protein 20080402 {GO:0007603=TAS, GO:0010897=IDA, GO:0010903=IC, GO:0005615=IDA, GO:0034361=IDA, GO:0042953=IEA, GO:0010987=IMP, GO:0034363=IDA, GO:0019433=IDA, GO:0010989=IMP, GO:0055102=IDA, GO:0042632=IMP, GO:0033344=IDA, GO:0043691=IC, GO:0034366=IDA, GO:0051005=IDA, GO:0007186=IDA, GO:0034375=IMP, GO:0042157=TAS, GO:0006641=IMP, GO:0006642=IEA, GO:0045833=IDA, GO:0006629=TAS, GO:0050995=IDA, GO:0042627=IDA, GO:0043434=IEA, GO:0070328=IMP, GO:0044281=TAS, GO:0034379=TAS, GO:0008289=IEA, GO:0006954=IEA, GO:0005543=IDA, GO:0034382=IDA, GO:0015485=IC, GO:0070653=IPI, GO:0030234=IDA, GO:0060621=IMP, GO:0008203=IEA, GO:0032489=IDA, GO:0007584=IEA, GO:0042493=IEA, GO:0045717=IDA, GO:0005576=TAS, GO:0001523=TAS, GO:0010916=IDA, GO:0033700=IDA, GO:0048261=IDA, GO:0006869=IEA, GO:0005769=TAS} G-protein coupled receptor signaling pathway, cholesterol efflux, cholesterol homeostasis, cholesterol metabolic process, chylomicron remnant clearance, high-density lipoprotein particle remodeling, inflammatory response, lipid metabolic process, lipid transport, lipoprotein metabolic process, lipoprotein transport, negative regulation of cholesterol import, negative regulation of fatty acid biosynthetic process, negative regulation of high-density lipoprotein particle clearance, negative regulation of lipid catabolic process, negative regulation of lipid metabolic process, negative regulation of lipoprotein lipase activity, negative regulation of low-density lipoprotein particle clearance, negative regulation of receptor-mediated endocytosis, negative regulation of triglyceride catabolic process, negative regulation of very-low-density lipoprotein particle clearance, negative regulation of very-low-density lipoprotein particle remodeling, phospholipid efflux, phototransduction, visible light, regulation of Cdc42 protein signal transduction, response to drug, response to nutrient, response to peptide hormone stimulus, retinoid metabolic process, reverse cholesterol transport, small molecule metabolic process, triglyceride catabolic process, triglyceride homeostasis, triglyceride metabolic process, triglyceride mobilization, very-low-density lipoprotein particle assembly chylomicron, early endosome, extracellular region, extracellular space, intermediate-density lipoprotein particle, spherical high-density lipoprotein particle, very-low-density lipoprotein particle cholesterol binding, enzyme regulator activity, high-density lipoprotein particle receptor binding, lipase inhibitor activity, lipid binding, phospholipid binding Human APOC4 BHF-UCL UniProtKB {GO:0034361=PMID:12700345, GO:0006629=PMID:8530039, GO:0034364=PMID:12700345, GO:0010890=PMID:18809223, GO:0070328=PMID:8827523, GO:0005319=PMID:8530039} P55056 Apolipoprotein C-IV protein 20090528 {GO:0034361=IDA, GO:0006629=TAS, GO:0034364=IDA, GO:0010890=IMP, GO:0070328=IMP, GO:0005319=TAS} lipid metabolic process, positive regulation of sequestering of triglyceride, triglyceride homeostasis high-density lipoprotein particle, very-low-density lipoprotein particle lipid transporter activity Human APOD GOC UniProtKB {GO:0006629=PMID:19176353, GO:0005515=PMID:7918467, GO:0005215=GO_REF:0000002, GO:0048471=PMID:14551159, GO:0005783=GO_REF:0000024, GO:0042246=GO_REF:0000024, GO:0048678=GO_REF:0000024, GO:0071638=PMID:18842892, GO:0005615=PMID:21705670, GO:0030425=GO_REF:0000024, GO:0008289=GO_REF:0000002, GO:0051895=PMID:21705670, GO:0005622=GO_REF:0000019, GO:0015485=PMID:9278274, GO:0014012=GO_REF:0000024, GO:0043025=GO_REF:0000024, GO:0006006=PMID:19176353, GO:0010642=PMID:14551159, GO:2000405=PMID:18842892, GO:0060588=GO_REF:0000019, GO:0042493=GO_REF:0000024, GO:0007568=PMID:20023409, GO:0036094=GO_REF:0000002, GO:0005576=PMID:14718574, GO:0001525=PMID:21705670, GO:0022626=GO_REF:0000024, GO:0007420=GO_REF:0000024, GO:0006869=PMID:3453108, GO:1900016=PMID:18842892, GO:0000302=PMID:18419796, GO:0005319=PMID:3453108} P05090 Apolipoprotein D protein 20130413 {GO:0006629=IDA, GO:0005515=IPI, GO:0005215=IEA, GO:0048471=IDA, GO:0005783=ISS, GO:0042246=ISS, GO:0048678=ISS, GO:0071638=IDA, GO:0005615=IDA, GO:0030425=ISS, GO:0008289=IEA, GO:0051895=IMP, GO:0005622=IEA, GO:0015485=IDA, GO:0014012=ISS, GO:0043025=ISS, GO:0006006=IDA, GO:0010642=IDA, GO:2000405=IDA, GO:0060588=IEA, GO:0042493=ISS, GO:0007568=NAS, GO:0036094=IEA, GO:0005576=NAS, GO:0001525=NAS, GO:0022626=ISS, GO:0007420=ISS, GO:0006869=NAS, GO:1900016=IDA, GO:0000302=IDA, GO:0005319=NAS} aging, angiogenesis, brain development, glucose metabolic process, lipid metabolic process, lipid transport, negative regulation of T cell migration, negative regulation of cytokine production involved in inflammatory response, negative regulation of focal adhesion assembly, negative regulation of lipoprotein lipid oxidation, negative regulation of monocyte chemotactic protein-1 production, negative regulation of platelet-derived growth factor receptor signaling pathway, peripheral nervous system axon regeneration, response to axon injury, response to drug, response to reactive oxygen species, tissue regeneration cytosolic ribosome, dendrite, endoplasmic reticulum, extracellular region, extracellular space, intracellular, neuronal cell body, perinuclear region of cytoplasm cholesterol binding, lipid binding, lipid transporter activity, protein binding, small molecule binding, transporter activity Human APOE BHF-UCL UniProtKB {GO:0005515=PMID:21593558, GO:0048709=GO_REF:0000019, GO:0046911=PMID:9685360, GO:0048844=GO_REF:0000019, GO:0034361=PMID:17154273, GO:0071397=GO_REF:0000019, GO:0034364=PMID:210174, GO:0034363=PMID:17336988, GO:0034362=PMID:8245722, GO:0034447=PMID:9649566, GO:0042632=PMID:9649566, GO:0032868=GO_REF:0000019, GO:0005794=GO_REF:0000019, GO:0046982=PMID:8245722, GO:0007271=PMID:9622609, GO:0034372=PMID:12401887, GO:0034374=GO_REF:0000019, GO:0051000=PMID:8995232, GO:0034375=PMID:12401887, GO:0006641=PMID:9649566, GO:0005319=PMID:17305370, GO:0010544=PMID:8995232, GO:0006629=Reactome:REACT_602, GO:0045471=GO_REF:0000019, GO:0045541=PMID:1917954, GO:0010873=PMID:15654758, GO:0042627=PMID:16935699, GO:0044281=Reactome:REACT_111217, GO:0070326=PMID:1384047, GO:0019934=PMID:8995232, GO:0030425=PMID:8083695, GO:0010875=PMID:12401887, GO:0034384=PMID:210175, GO:0034382=PMID:7175379, GO:0014012=GO_REF:0000019, GO:0042311=GO_REF:0000019, GO:0007010=PMID:9622609, GO:0034380=PMID:17305370, GO:0032526=GO_REF:0000019, GO:0032489=PMID:16443932, GO:0005770=GO_REF:0000019, GO:0048156=PMID:7566652, GO:0046907=PMID:9622609, GO:0005576=Reactome:REACT_160272, GO:0032805=PMID:15950758, GO:0071363=GO_REF:0000019, GO:0050728=PMID:8995232, GO:0030195=PMID:8995232, GO:0030828=PMID:8995232, GO:0005769=Reactome:REACT_160272, GO:0010468=GO_REF:0000019, GO:0008219=GO_REF:0000037, GO:0006707=GO_REF:0000019, GO:0007603=Reactome:REACT_160125, GO:0002021=GO_REF:0000019, GO:0042803=PMID:8245722, GO:0042802=PMID:4066713, GO:0043524=GO_REF:0000019, GO:0048168=PMID:9622609, GO:0046848=GO_REF:0000019, GO:0043025=PMID:8083695, GO:0006979=GO_REF:0000019, GO:0033344=PMID:11162594, GO:0016209=PMID:9685360, GO:0007568=GO_REF:0000019, GO:0043691=PMID:8127890, GO:0031232=GO_REF:0000019, GO:0006898=PMID:1917954, GO:0051651=GO_REF:0000019, GO:0007186=PMID:16443932, GO:0071347=GO_REF:0000019, GO:0042157=Reactome:REACT_13621, GO:0000302=PMID:11743999, GO:0042159=GO_REF:0000019, GO:0043537=PMID:9685360, GO:0042158=GO_REF:0000019, GO:0051044=PMID:15950758, GO:0005886=Reactome:REACT_6849, GO:0007263=PMID:8995232, GO:0017127=GO_REF:0000019, GO:0045773=GO_REF:0000019, GO:0008289=PMID:4066713, GO:0060228=PMID:15654758, GO:0005737=PMID:8083695, GO:0030516=PMID:9622609, GO:0001540=PMID:11305869, GO:0005543=PMID:4066713, GO:0043407=PMID:9685360, GO:0008201=PMID:2745454, GO:0008203=PMID:9649566, GO:0071813=GO_REF:0000019, GO:0043066=PMID:9685360, GO:0006874=GO_REF:0000019, GO:0006917=PMID:12753088, GO:0001523=Reactome:REACT_24968, GO:0033700=PMID:11162594, GO:0001937=PMID:9685360, GO:0006869=GO_REF:0000038, GO:0050750=PMID:17326667} P02649 Apolipoprotein E protein 20080402 {GO:0005515=IPI, GO:0048709=IEA, GO:0046911=IDA, GO:0048844=IEA, GO:0034361=IDA, GO:0071397=IEA, GO:0034364=IDA, GO:0034363=IDA, GO:0034362=IDA, GO:0034447=IMP, GO:0042632=IDA, GO:0032868=IEA, GO:0005794=IEA, GO:0046982=IPI, GO:0007271=TAS, GO:0034372=IGI, GO:0034374=IEA, GO:0051000=IDA, GO:0034375=IGI, GO:0006641=IDA, GO:0005319=IDA, GO:0010544=IDA, GO:0006629=TAS, GO:0045471=IEA, GO:0045541=IDA, GO:0010873=IDA, GO:0042627=IDA, GO:0044281=TAS, GO:0070326=IDA, GO:0019934=IDA, GO:0030425=NAS, GO:0010875=IGI, GO:0034384=IDA, GO:0034382=IMP, GO:0014012=IEA, GO:0042311=IEA, GO:0007010=TAS, GO:0034380=IDA, GO:0032526=IEA, GO:0032489=IDA, GO:0005770=IEA, GO:0048156=IPI, GO:0046907=TAS, GO:0005576=TAS, GO:0032805=IDA, GO:0071363=IEA, GO:0050728=IC, GO:0030195=IDA, GO:0030828=IDA, GO:0005769=TAS, GO:0010468=IEA, GO:0008219=IEA, GO:0006707=IEA, GO:0007603=TAS, GO:0002021=IEA, GO:0042803=IDA, GO:0042802=IDA, GO:0043524=IEA, GO:0048168=TAS, GO:0046848=IEA, GO:0043025=NAS, GO:0006979=IEA, GO:0033344=IDA, GO:0016209=IDA, GO:0007568=IEA, GO:0043691=IDA, GO:0031232=IEA, GO:0006898=IDA, GO:0051651=IEA, GO:0007186=IDA, GO:0071347=IEA, GO:0042157=TAS, GO:0000302=NAS, GO:0042159=IEA, GO:0043537=IDA, GO:0042158=IEA, GO:0051044=IDA, GO:0005886=TAS, GO:0007263=IDA, GO:0017127=IEA, GO:0045773=IEA, GO:0008289=IDA, GO:0060228=IDA, GO:0005737=NAS, GO:0030516=TAS, GO:0001540=IDA, GO:0005543=IDA, GO:0043407=IDA, GO:0008201=IDA, GO:0008203=IDA, GO:0071813=IEA, GO:0043066=IDA, GO:0006874=IEA, GO:0006917=IDA, GO:0001523=TAS, GO:0033700=IDA, GO:0001937=IDA, GO:0006869=IEA, GO:0050750=IPI} G-protein coupled receptor signaling pathway, aging, artery morphogenesis, cGMP-mediated signaling, cell death, cellular calcium ion homeostasis, cellular response to cholesterol, cellular response to growth factor stimulus, cellular response to interleukin-1, cholesterol catabolic process, cholesterol efflux, cholesterol homeostasis, cholesterol metabolic process, chylomicron remnant clearance, cytoskeleton organization, high-density lipoprotein particle assembly, high-density lipoprotein particle clearance, high-density lipoprotein particle remodeling, induction of apoptosis, intracellular transport, lipid metabolic process, lipid transport, lipoprotein biosynthetic process, lipoprotein catabolic process, lipoprotein metabolic process, low-density lipoprotein particle remodeling, maintenance of location in cell, negative regulation of MAP kinase activity, negative regulation of apoptotic process, negative regulation of blood coagulation, negative regulation of blood vessel endothelial cell migration, negative regulation of cholesterol biosynthetic process, negative regulation of endothelial cell proliferation, negative regulation of inflammatory response, negative regulation of neuron apoptotic process, negative regulation of platelet activation, nitric oxide mediated signal transduction, oligodendrocyte differentiation, peripheral nervous system axon regeneration, phospholipid efflux, phototransduction, visible light, positive regulation of axon extension, positive regulation of cGMP biosynthetic process, positive regulation of cholesterol efflux, positive regulation of cholesterol esterification, positive regulation of low-density lipoprotein particle receptor catabolic process, positive regulation of membrane protein ectodomain proteolysis, positive regulation of nitric-oxide synthase activity, receptor-mediated endocytosis, regulation of Cdc42 protein signal transduction, regulation of axon extension, regulation of gene expression, regulation of neuronal synaptic plasticity, response to dietary excess, response to ethanol, response to insulin stimulus, response to oxidative stress, response to reactive oxygen species, response to retinoic acid, retinoid metabolic process, reverse cholesterol transport, small molecule metabolic process, synaptic transmission, cholinergic, triglyceride metabolic process, vasodilation, very-low-density lipoprotein particle clearance, very-low-density lipoprotein particle remodeling Golgi apparatus, chylomicron, cytoplasm, dendrite, early endosome, extracellular region, extrinsic to external side of plasma membrane, high-density lipoprotein particle, intermediate-density lipoprotein particle, late endosome, low-density lipoprotein particle, neuronal cell body, plasma membrane, very-low-density lipoprotein particle antioxidant activity, beta-amyloid binding, cholesterol transporter activity, heparin binding, hydroxyapatite binding, identical protein binding, lipid binding, lipid transporter activity, lipoprotein particle binding, low-density lipoprotein particle receptor binding, metal chelating activity, phosphatidylcholine-sterol O-acyltransferase activator activity, phospholipid binding, protein binding, protein heterodimerization activity, protein homodimerization activity, tau protein binding, very-low-density lipoprotein particle receptor binding Human APOF PINC UniProtKB {GO:0006629=PMID:8093033, GO:0033344=GO_REF:0000019, GO:0015485=PMID:6816269, GO:0034364=GO_REF:0000037, GO:0006869=PMID:6816269, GO:0034362=GO_REF:0000037, GO:0005102=PMID:8093033, GO:0006641=GO_REF:0000019, GO:0005576=PMID:14718574, GO:0005319=PMID:6816269, GO:0008203=GO_REF:0000019} Q13790 Apolipoprotein F protein 20030904 {GO:0006629=TAS, GO:0033344=IEA, GO:0015485=TAS, GO:0034364=IEA, GO:0006869=TAS, GO:0034362=IEA, GO:0005102=TAS, GO:0006641=IEA, GO:0005576=NAS, GO:0005319=TAS, GO:0008203=IEA} cholesterol efflux, cholesterol metabolic process, lipid metabolic process, lipid transport, triglyceride metabolic process extracellular region, high-density lipoprotein particle, low-density lipoprotein particle cholesterol binding, lipid transporter activity, receptor binding Human APOH BHF-UCL UniProtKB {GO:0005515=PMID:16480936, GO:0043499=PMID:16480936, GO:0042627=PMID:222615, GO:0005615=PMID:15486070, GO:0008289=PMID:222615, GO:0034361=PMID:222615, GO:0005543=PMID:15486070, GO:0001948=PMID:9269765, GO:0034364=PMID:222615, GO:0008201=GO_REF:0000037, GO:0033033=PMID:15534879, GO:0034197=PMID:7078428, GO:0009986=PMID:16480936, GO:0051918=PMID:14726399, GO:0051917=PMID:16480936, GO:0060230=PMID:7417307, GO:0010596=PMID:17872974, GO:0034392=PMID:15534879, GO:0030193=GO_REF:0000019, GO:0030194=PMID:16480936, GO:0001937=PMID:17872974, GO:0007597=PMID:4052628, GO:0030195=PMID:4052628, GO:0016525=PMID:17872974, GO:0006641=PMID:7417307, GO:0031639=PMID:16480936, GO:0051006=PMID:7417307} P02749 Beta-2-glycoprotein 1 protein 20080402 {GO:0005515=IPI, GO:0043499=IDA, GO:0042627=IDA, GO:0005615=IDA, GO:0008289=IDA, GO:0034361=IDA, GO:0005543=IDA, GO:0001948=IPI, GO:0034364=IDA, GO:0008201=IEA, GO:0033033=IDA, GO:0034197=ISS, GO:0009986=IDA, GO:0051918=IDA, GO:0051917=IDA, GO:0060230=IDA, GO:0010596=IDA, GO:0034392=IDA, GO:0030193=IEA, GO:0030194=TAS, GO:0001937=IDA, GO:0007597=IDA, GO:0030195=IDA, GO:0016525=IDA, GO:0006641=IDA, GO:0031639=IDA, GO:0051006=IDA} blood coagulation, intrinsic pathway, negative regulation of angiogenesis, negative regulation of blood coagulation, negative regulation of endothelial cell migration, negative regulation of endothelial cell proliferation, negative regulation of fibrinolysis, negative regulation of myeloid cell apoptotic process, negative regulation of smooth muscle cell apoptotic process, plasminogen activation, positive regulation of blood coagulation, positive regulation of lipoprotein lipase activity, regulation of blood coagulation, regulation of fibrinolysis, triglyceride metabolic process, triglyceride transport cell surface, chylomicron, extracellular space, high-density lipoprotein particle, very-low-density lipoprotein particle eukaryotic cell surface binding, glycoprotein binding, heparin binding, lipid binding, lipoprotein lipase activator activity, phospholipid binding, protein binding Human APOL1 BHF-UCL UniProtKB {GO:0005515=PMID:12621437, GO:0006821=PMID:16020735, GO:0031224=PMID:16020735, GO:0005576=Reactome:REACT_160200, GO:0005615=PMID:17192540, GO:0005254=PMID:16020735, GO:0008289=PMID:16020735, GO:0034361=PMID:17154273, GO:0034364=PMID:9325276, GO:0045087=PMID:17192540, GO:0006869=GO_REF:0000037, GO:0019835=PMID:12621437, GO:0042157=GO_REF:0000002, GO:0031640=PMID:12621437, GO:0008203=GO_REF:0000037} O14791 Apolipoprotein L1 protein 20080403 {GO:0005515=IPI, GO:0006821=IDA, GO:0031224=IC, GO:0005576=TAS, GO:0005615=IDA, GO:0005254=IDA, GO:0008289=IDA, GO:0034361=IDA, GO:0034364=IDA, GO:0045087=IDA, GO:0006869=IEA, GO:0019835=IDA, GO:0042157=IEA, GO:0031640=IDA, GO:0008203=IEA} chloride transport, cholesterol metabolic process, cytolysis, innate immune response, killing of cells of other organism, lipid transport, lipoprotein metabolic process extracellular region, extracellular space, high-density lipoprotein particle, intrinsic to membrane, very-low-density lipoprotein particle chloride channel activity, lipid binding, protein binding Human GO:0005254 APOL2 UniProtKB UniProtKB {GO:0006629=PMID:11944986, GO:0008035=PMID:11374903, GO:0060135=PMID:11374903, GO:0006869=PMID:11374903, GO:0005789=PMID:11374903, GO:0005102=PMID:11374903, GO:0042157=GO_REF:0000002, GO:0007275=PMID:11374903, GO:0005576=GO_REF:0000002, GO:0006953=PMID:11374903, GO:0008203=PMID:11374903, GO:0008289=PMID:11374903} Q9BQE5 Apolipoprotein L2 protein 20080408 {GO:0006629=NAS, GO:0008035=NAS, GO:0060135=NAS, GO:0006869=NAS, GO:0005789=NAS, GO:0005102=NAS, GO:0042157=IEA, GO:0007275=NAS, GO:0005576=IEA, GO:0006953=NAS, GO:0008203=NAS, GO:0008289=NAS} acute-phase response, cholesterol metabolic process, lipid metabolic process, lipid transport, lipoprotein metabolic process, maternal process involved in female pregnancy, multicellular organismal development endoplasmic reticulum membrane, extracellular region high-density lipoprotein particle binding, lipid binding, receptor binding Human APOL5 UniProtKB UniProtKB {GO:0008035=PMID:11374903, GO:0006629=PMID:11374903, GO:0005737=GO_REF:0000039, GO:0006869=GO_REF:0000037, GO:0042157=GO_REF:0000002, GO:0005576=GO_REF:0000002, GO:0005575=GO_REF:0000015, GO:0008289=GO_REF:0000002} Q9BWW9 Apolipoprotein L5 protein 20061026 {GO:0008035=NAS, GO:0006629=NAS, GO:0005737=IEA, GO:0006869=IEA, GO:0042157=IEA, GO:0005576=IEA, GO:0005575=ND, GO:0008289=IEA} lipid metabolic process, lipid transport, lipoprotein metabolic process cellular_component, cytoplasm, extracellular region high-density lipoprotein particle binding, lipid binding Human APOL6 UniProtKB UniProtKB {GO:0005737=GO_REF:0000029, GO:0006869=GO_REF:0000029, GO:0042157=GO_REF:0000002, GO:0005576=GO_REF:0000002, GO:0005319=GO_REF:0000029, GO:0008289=GO_REF:0000002} Q9BWW8 Apolipoprotein L6 protein 20021105 {GO:0005737=NAS, GO:0006869=NAS, GO:0042157=IEA, GO:0005576=IEA, GO:0005319=NAS, GO:0008289=IEA} lipid transport, lipoprotein metabolic process cytoplasm, extracellular region lipid binding, lipid transporter activity Human APOLD1 UniProtKB UniProtKB {GO:0001666=GO_REF:0000019, GO:0005886=GO_REF:0000039, GO:0006869=GO_REF:0000002, GO:0042157=GO_REF:0000002, GO:0042118=GO_REF:0000019, GO:0005576=GO_REF:0000002, GO:0001525=GO_REF:0000019, GO:0016021=GO_REF:0000037, GO:0030154=GO_REF:0000037, GO:0045601=GO_REF:0000019, GO:0008289=GO_REF:0000002} Q96LR9 Apolipoprotein L domain-containing protein 1 protein 20130413 {GO:0001666=IEA, GO:0005886=IEA, GO:0006869=IEA, GO:0042157=IEA, GO:0042118=IEA, GO:0005576=IEA, GO:0001525=IEA, GO:0016021=IEA, GO:0030154=IEA, GO:0045601=IEA, GO:0008289=IEA} angiogenesis, cell differentiation, endothelial cell activation, lipid transport, lipoprotein metabolic process, regulation of endothelial cell differentiation, response to hypoxia extracellular region, integral to membrane, plasma membrane lipid binding Human UniProtKB-SubCell:SL-0039 APOM BHF-UCL UniProtKB {GO:0042632=PMID:15793583, GO:0033344=PMID:15793583, GO:0016209=PMID:22204862, GO:0043691=PMID:15793583, GO:0034366=PMID:16682745, GO:0009749=GO_REF:0000019, GO:0034361=PMID:17154273, GO:0005543=PMID:22204862, GO:0034384=PMID:15793583, GO:0034365=PMID:15793583, GO:0034364=PMID:22204862, GO:0005887=PMID:10531326, GO:0034375=PMID:18006500, GO:0034362=PMID:16682745, GO:0034380=PMID:15793583, GO:0034445=PMID:22204862, GO:0042157=GO_REF:0000019, GO:0005319=PMID:16682745} O95445 Apolipoprotein M protein 20120531 {GO:0042632=IC, GO:0033344=IMP, GO:0016209=IDA, GO:0043691=ISS, GO:0034366=IDA, GO:0009749=IEA, GO:0034361=IDA, GO:0005543=IDA, GO:0034384=ISS, GO:0034365=IDA, GO:0034364=IDA, GO:0005887=TAS, GO:0034375=IMP, GO:0034362=IDA, GO:0034380=ISS, GO:0034445=IDA, GO:0042157=IEA, GO:0005319=IDA} cholesterol efflux, cholesterol homeostasis, high-density lipoprotein particle assembly, high-density lipoprotein particle clearance, high-density lipoprotein particle remodeling, lipoprotein metabolic process, negative regulation of plasma lipoprotein particle oxidation, response to glucose stimulus, reverse cholesterol transport discoidal high-density lipoprotein particle, high-density lipoprotein particle, integral to plasma membrane, low-density lipoprotein particle, spherical high-density lipoprotein particle, very-low-density lipoprotein particle antioxidant activity, lipid transporter activity, phospholipid binding Human APOO BHF-UCL UniProtKB {GO:0034361=GO_REF:0000037, GO:0034364=GO_REF:0000037, GO:0034362=GO_REF:0000037, GO:0006869=GO_REF:0000037, GO:0016021=GO_REF:0000037, GO:0005615=PMID:22261194} Q9BUR5 Apolipoprotein O protein 20120228 {GO:0034361=IEA, GO:0034364=IEA, GO:0034362=IEA, GO:0006869=IEA, GO:0016021=IEA, GO:0005615=ISS} lipid transport extracellular space, high-density lipoprotein particle, integral to membrane, low-density lipoprotein particle, very-low-density lipoprotein particle Human UniProtKB:F1SPZ9 APOOL UniProtKB UniProtKB {GO:0005743=GO_REF:0000019, GO:0005576=GO_REF:0000039} Q6UXV4 Apolipoprotein O-like protein 20130413 {GO:0005743=IEA, GO:0005576=IEA} extracellular region, mitochondrial inner membrane Human UniProtKB-SubCell:SL-0243 APOPT1 UniProtKB UniProtKB {GO:0005739=GO_REF:0000039, GO:0043280=GO_REF:0000019, GO:0090200=GO_REF:0000019, GO:0034393=GO_REF:0000019, GO:0097193=GO_REF:0000019} Q96IL0 Apoptogenic protein 1, mitochondrial protein 20130413 {GO:0005739=IEA, GO:0043280=IEA, GO:0090200=IEA, GO:0034393=IEA, GO:0097193=IEA} intrinsic apoptotic signaling pathway, positive regulation of cysteine-type endopeptidase activity involved in apoptotic process, positive regulation of release of cytochrome c from mitochondria, positive regulation of smooth muscle cell apoptotic process mitochondrion Human UniProtKB-SubCell:SL-0173 APP BHF-UCL UniProtKB {GO:0005515=PMID:19849849, GO:0031594=GO_REF:0000019, GO:0046914=GO_REF:0000002, GO:0045202=PMID:11988176, GO:0007409=GO_REF:0000024, GO:0051402=PMID:19225519, GO:0031175=GO_REF:0000024, GO:0043231=GO_REF:0000052, GO:0006878=GO_REF:0000024, GO:0007219=GO_REF:0000037, GO:0030198=GO_REF:0000024, GO:0007176=GO_REF:0000024, GO:0050885=GO_REF:0000019, GO:0006979=GO_REF:0000019, GO:0006378=GO_REF:0000024, GO:0005794=GO_REF:0000052, GO:0009986=PMID:7593229, GO:0007617=GO_REF:0000024, GO:0043393=GO_REF:0000019, GO:0050803=GO_REF:0000024, GO:0030168=Reactome:REACT_798, GO:0016358=GO_REF:0000024, GO:0006897=GO_REF:0000024, GO:0016504=GO_REF:0000019, GO:0035235=GO_REF:0000024, GO:0045931=GO_REF:0000024, GO:0005887=PMID:10806211, GO:0045087=Reactome:REACT_6802, GO:0008542=GO_REF:0000024, GO:0008088=GO_REF:0000024, GO:0008344=GO_REF:0000024, GO:0030424=GO_REF:0000024, GO:0048471=GO_REF:0000019, GO:0005886=PMID:12805363, GO:0004867=PMID:10652580, GO:0051425=PMID:12805363, GO:0051233=GO_REF:0000019, GO:0035872=Reactome:REACT_75913, GO:0005829=Reactome:REACT_75877, GO:0016322=GO_REF:0000024, GO:0000085=GO_REF:0000024, GO:0005737=PMID:18509662, GO:0051563=GO_REF:0000019, GO:0001967=GO_REF:0000019, GO:0070851=GO_REF:0000019, GO:0043197=PMID:11988176, GO:0043198=PMID:11988176, GO:0016199=GO_REF:0000024, GO:0048669=GO_REF:0000024, GO:0045944=GO_REF:0000019, GO:0040014=GO_REF:0000024, GO:0031093=Reactome:REACT_21351, GO:0007626=GO_REF:0000024, GO:0007155=GO_REF:0000037, GO:0008201=GO_REF:0000037, GO:0008203=GO_REF:0000019, GO:0005102=PMID:19849849, GO:0045177=GO_REF:0000019, GO:0005576=Reactome:REACT_75905, GO:0006917=GO_REF:0000019, GO:0003677=GO_REF:0000024, GO:0006417=GO_REF:0000024, GO:0005905=GO_REF:0000039, GO:0045665=GO_REF:0000019, GO:0007596=Reactome:REACT_604, GO:0035253=GO_REF:0000019, GO:0002576=Reactome:REACT_318, GO:0051124=GO_REF:0000019, GO:0006468=GO_REF:0000024, GO:0030900=GO_REF:0000019, GO:0016021=GO_REF:0000024} P05067 Amyloid beta A4 protein protein 20101122 {GO:0005515=IPI, GO:0031594=IEA, GO:0046914=IEA, GO:0045202=IDA, GO:0007409=ISS, GO:0051402=IMP, GO:0031175=ISS, GO:0043231=IDA, GO:0006878=ISS, GO:0007219=IEA, GO:0030198=ISS, GO:0007176=ISS, GO:0050885=IEA, GO:0006979=IEA, GO:0006378=ISS, GO:0005794=IDA, GO:0009986=IDA, GO:0007617=ISS, GO:0043393=IEA, GO:0050803=ISS, GO:0030168=TAS, GO:0016358=ISS, GO:0006897=ISS, GO:0016504=IEA, GO:0035235=ISS, GO:0045931=ISS, GO:0005887=TAS, GO:0045087=TAS, GO:0008542=ISS, GO:0008088=ISS, GO:0008344=ISS, GO:0030424=ISS, GO:0048471=IEA, GO:0005886=IDA, GO:0004867=IDA, GO:0051425=IPI, GO:0051233=IEA, GO:0035872=TAS, GO:0005829=TAS, GO:0016322=ISS, GO:0000085=ISS, GO:0005737=IDA, GO:0051563=IEA, GO:0001967=IEA, GO:0070851=IEA, GO:0043197=IDA, GO:0043198=IDA, GO:0016199=ISS, GO:0048669=ISS, GO:0045944=IEA, GO:0040014=ISS, GO:0031093=TAS, GO:0007626=ISS, GO:0007155=IEA, GO:0008201=IEA, GO:0008203=IEA, GO:0005102=IPI, GO:0045177=IEA, GO:0005576=TAS, GO:0006917=IEA, GO:0003677=ISS, GO:0006417=ISS, GO:0005905=IEA, GO:0045665=IEA, GO:0007596=TAS, GO:0035253=IEA, GO:0002576=TAS, GO:0051124=IEA, GO:0006468=ISS, GO:0030900=IEA, GO:0016021=ISS} G2 phase of mitotic cell cycle, Notch signaling pathway, adult locomotory behavior, axon cargo transport, axon midline choice point recognition, axonogenesis, blood coagulation, cell adhesion, cellular copper ion homeostasis, cholesterol metabolic process, collateral sprouting in absence of injury, dendrite development, endocytosis, extracellular matrix organization, forebrain development, induction of apoptosis, innate immune response, ionotropic glutamate receptor signaling pathway, locomotory behavior, mRNA polyadenylation, mating behavior, negative regulation of neuron differentiation, neuromuscular process controlling balance, neuron apoptotic process, neuron projection development, neuron remodeling, nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway, platelet activation, platelet degranulation, positive regulation of mitotic cell cycle, positive regulation of transcription from RNA polymerase II promoter, protein phosphorylation, regulation of epidermal growth factor-activated receptor activity, regulation of multicellular organism growth, regulation of protein binding, regulation of synapse structure and activity, regulation of translation, response to oxidative stress, smooth endoplasmic reticulum calcium ion homeostasis, suckling behavior, synaptic growth at neuromuscular junction, visual learning Golgi apparatus, apical part of cell, axon, cell surface, ciliary rootlet, coated pit, cytoplasm, cytosol, dendritic shaft, dendritic spine, extracellular region, integral to membrane, integral to plasma membrane, intracellular membrane-bounded organelle, neuromuscular junction, perinuclear region of cytoplasm, plasma membrane, platelet alpha granule lumen, spindle midzone, synapse DNA binding, PTB domain binding, growth factor receptor binding, heparin binding, peptidase activator activity, protein binding, receptor binding, serine-type endopeptidase inhibitor activity, transition metal ion binding Human APPBP2 IntAct UniProtKB {GO:0005515=PMID:19060904, GO:0005737=PMID:11742091, GO:0005875=PMID:9843960, GO:0005874=GO_REF:0000037, GO:0046907=PMID:9843960, GO:0005634=PMID:11742091, GO:0003777=PMID:9843960, GO:0006886=PMID:9843960, GO:0030659=PMID:9843960} Q92624 Amyloid protein-binding protein 2 protein 20130415 {GO:0005515=IPI, GO:0005737=NAS, GO:0005875=TAS, GO:0005874=IEA, GO:0046907=IDA, GO:0005634=NAS, GO:0003777=TAS, GO:0006886=TAS, GO:0030659=IDA} intracellular protein transport, intracellular transport cytoplasm, cytoplasmic vesicle membrane, microtubule, microtubule associated complex, nucleus microtubule motor activity, protein binding Human UniProtKB:Q9BT88 APPL1 BHF-UCL UniProtKB {GO:0008286=PMID:17848569, GO:0005515=PMID:16622416, GO:0012506=PMID:17848569, GO:0008283=PMID:15016378, GO:0006915=Reactome:REACT_578, GO:0005634=PMID:15016378, GO:0042981=Reactome:REACT_13648, GO:0043422=PMID:17848569, GO:0005829=PMID:17848569, GO:0007165=PMID:10490823, GO:0007049=GO_REF:0000037, GO:0005737=PMID:10490823, GO:0005543=GO_REF:0000002, GO:0046324=PMID:17848569, GO:0016581=PMID:15016378, GO:0031901=GO_REF:0000039, GO:0090003=PMID:17848569, GO:0010008=Reactome:REACT_22412} Q9UKG1 DCC-interacting protein 13-alpha protein 20090227 {GO:0008286=TAS, GO:0005515=IPI, GO:0012506=IDA, GO:0008283=IDA, GO:0006915=TAS, GO:0005634=IDA, GO:0042981=TAS, GO:0043422=IPI, GO:0005829=IDA, GO:0007165=TAS, GO:0007049=IEA, GO:0005737=IC, GO:0005543=IEA, GO:0046324=IMP, GO:0016581=IDA, GO:0031901=IEA, GO:0090003=IMP, GO:0010008=TAS} apoptotic process, cell cycle, cell proliferation, insulin receptor signaling pathway, regulation of apoptotic process, regulation of establishment of protein localization to plasma membrane, regulation of glucose import, signal transduction NuRD complex, cytoplasm, cytosol, early endosome membrane, endosome membrane, nucleus, vesicle membrane phospholipid binding, protein binding, protein kinase B binding Human UniProtKB:P47197 APPL2 HGNC UniProtKB {GO:0005515=PMID:17030088, GO:0007165=PMID:15016378, GO:0005737=PMID:15016378, GO:0007049=GO_REF:0000037, GO:0005543=GO_REF:0000002, GO:0016581=PMID:15016378, GO:0008283=PMID:15016378, GO:0031901=GO_REF:0000039, GO:0005634=PMID:15016378, GO:0010008=PMID:15016378} Q8NEU8 DCC-interacting protein 13-beta protein 20070503 {GO:0005515=IPI, GO:0007165=TAS, GO:0005737=IC, GO:0007049=IEA, GO:0005543=IEA, GO:0016581=IDA, GO:0008283=IDA, GO:0031901=IEA, GO:0005634=IDA, GO:0010008=IDA} cell cycle, cell proliferation, signal transduction NuRD complex, cytoplasm, early endosome membrane, endosome membrane, nucleus phospholipid binding, protein binding Human UniProtKB:Q9UKG1 APRT HPA UniProtKB {GO:0032869=GO_REF:0000019, GO:0016208=PMID:15196008, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0055086=Reactome:REACT_1698, GO:0044209=GO_REF:0000041, GO:0044281=Reactome:REACT_111217, GO:0002055=GO_REF:0000019, GO:0005829=Reactome:REACT_165, GO:0006166=GO_REF:0000019, GO:0005737=GO_REF:0000052, GO:0006168=GO_REF:0000019, GO:0007595=GO_REF:0000019, GO:0006144=Reactome:REACT_522, GO:0043101=Reactome:REACT_1923, GO:0009116=GO_REF:0000002, GO:0007625=GO_REF:0000019, GO:0016740=GO_REF:0000038, GO:0003999=Reactome:REACT_165} P07741 Adenine phosphoribosyltransferase protein 20100326 {GO:0032869=IEA, GO:0016208=IDA, GO:0005730=IDA, GO:0005634=IDA, GO:0055086=TAS, GO:0044209=IEA, GO:0044281=TAS, GO:0002055=IEA, GO:0005829=TAS, GO:0006166=IEA, GO:0005737=IDA, GO:0006168=IEA, GO:0007595=IEA, GO:0006144=TAS, GO:0043101=TAS, GO:0009116=IEA, GO:0007625=IEA, GO:0016740=IEA, GO:0003999=TAS} AMP salvage, adenine salvage, cellular response to insulin stimulus, grooming behavior, lactation, nucleobase-containing small molecule metabolic process, nucleoside metabolic process, purine nucleobase metabolic process, purine ribonucleoside salvage, purine-containing compound salvage, small molecule metabolic process cytoplasm, cytosol, nucleolus, nucleus AMP binding, adenine binding, adenine phosphoribosyltransferase activity, transferase activity Human APTX IntAct UniProtKB {GO:0051219=PMID:20008512, GO:0003725=PMID:16547001, GO:0005515=PMID:15044383, GO:0008967=PMID:17519253, GO:0033699=PMID:16547001, GO:0042542=PMID:15044383, GO:0008219=GO_REF:0000037, GO:0000012=PMID:17519253, GO:0000790=PMID:20008512, GO:0005730=PMID:15044383, GO:0003824=GO_REF:0000002, GO:0006974=PMID:15044383, GO:0003684=PMID:14755728, GO:0005737=GO_REF:0000039, GO:0003690=PMID:16547001, GO:0047485=PMID:16777843, GO:0031647=PMID:16777843, GO:0003682=PMID:15044383, GO:0008270=GO_REF:0000002, GO:0005654=PMID:16777843, GO:0000785=PMID:15044383, GO:0006266=GO_REF:0000019} Q7Z2E3 Aprataxin protein 20130415 {GO:0051219=IPI, GO:0003725=IDA, GO:0005515=IPI, GO:0008967=IDA, GO:0033699=IDA, GO:0042542=IDA, GO:0008219=IEA, GO:0000012=IDA, GO:0000790=IDA, GO:0005730=IDA, GO:0003824=IEA, GO:0006974=IMP, GO:0003684=IDA, GO:0005737=IEA, GO:0003690=IDA, GO:0047485=IPI, GO:0031647=IMP, GO:0003682=IDA, GO:0008270=IEA, GO:0005654=IDA, GO:0000785=IDA, GO:0006266=IEA} DNA ligation, cell death, regulation of protein stability, response to DNA damage stimulus, response to hydrogen peroxide, single strand break repair chromatin, cytoplasm, nuclear chromatin, nucleolus, nucleoplasm DNA 5'-adenosine monophosphate hydrolase activity, catalytic activity, chromatin binding, damaged DNA binding, double-stranded DNA binding, double-stranded RNA binding, phosphoglycolate phosphatase activity, phosphoprotein binding, protein N-terminus binding, protein binding, zinc ion binding Human UniProtKB:P09874 AQP1 GOC UniProtKB {GO:0005515=PMID:19447967, GO:0015079=GO_REF:0000024, GO:0005215=GO_REF:0000002, GO:0020003=GO_REF:0000024, GO:0070301=PMID:19424603, GO:0071732=PMID:14561230, GO:0071300=PMID:19424603, GO:0020005=PMID:18665841, GO:0031526=PMID:9013443, GO:0030157=PMID:12801959, GO:0035377=PMID:12766090, GO:0006884=PMID:11922632, GO:0034644=PMID:19424603, GO:0009925=PMID:17409744, GO:0015793=PMID:8584435, GO:0006833=Reactome:REACT_24023, GO:0005223=PMID:14561230, GO:0071474=PMID:11922632, GO:0031965=PMID:17645239, GO:0030950=PMID:19584911, GO:0071288=PMID:9321919, GO:0015696=PMID:19273840, GO:0071472=PMID:18509662, GO:0005267=PMID:11914159, GO:0033554=PMID:19268465, GO:0035378=PMID:17012249, GO:0035379=Reactome:REACT_121218, GO:0046878=PMID:15727941, GO:0005887=PMID:1722319, GO:0006182=PMID:14561230, GO:0085018=PMID:18665841, GO:0015701=Reactome:REACT_121380, GO:0071241=PMID:14561230, GO:0071280=PMID:8584435, GO:0005886=GO_REF:0000052, GO:0005634=PMID:17645239, GO:0044281=Reactome:REACT_111217, GO:0048146=PMID:16565507, GO:0016323=PMID:12801959, GO:0005737=PMID:18509662, GO:0016324=PMID:12801959, GO:0030184=PMID:16682607, GO:0030185=PMID:16682607, GO:0015250=Reactome:REACT_23841, GO:0042476=PMID:12522663, GO:0005372=PMID:9321919, GO:0006813=GO_REF:0000024, GO:0071805=PMID:11914159, GO:0043066=PMID:16565507, GO:0019725=PMID:19268465, GO:0042493=PMID:12172703, GO:0022857=PMID:17012249, GO:0071456=PMID:18275976, GO:0045177=PMID:14675051, GO:0015670=PMID:12745312, GO:0055085=Reactome:REACT_15518, GO:0045766=PMID:18275976, GO:0005903=PMID:16133142, GO:0042383=PMID:17409744, GO:0015168=PMID:8584435, GO:0021670=PMID:16133142, GO:0050891=PMID:17645239, GO:0051739=PMID:19273840, GO:0003097=PMID:9096382, GO:0033326=PMID:16814974, GO:0016021=GO_REF:0000038, GO:0071260=PMID:19268465, GO:0071320=PMID:18538351, GO:0071549=PMID:16711029} P29972 Aquaporin-1 protein 20130413 {GO:0005515=IPI, GO:0015079=ISS, GO:0005215=IEA, GO:0020003=ISS, GO:0070301=IDA, GO:0071732=IDA, GO:0071300=IDA, GO:0020005=IDA, GO:0031526=IDA, GO:0030157=IEP, GO:0035377=IDA, GO:0006884=IMP, GO:0034644=IDA, GO:0009925=IDA, GO:0015793=IDA, GO:0006833=TAS, GO:0005223=IDA, GO:0071474=IMP, GO:0031965=IDA, GO:0030950=IMP, GO:0071288=IDA, GO:0015696=IDA, GO:0071472=IDA, GO:0005267=IMP, GO:0033554=IDA, GO:0035378=IDA, GO:0035379=TAS, GO:0046878=IMP, GO:0005887=TAS, GO:0006182=IDA, GO:0085018=IMP, GO:0015701=TAS, GO:0071241=IDA, GO:0071280=IDA, GO:0005886=IDA, GO:0005634=IDA, GO:0044281=TAS, GO:0048146=IDA, GO:0016323=IDA, GO:0005737=IDA, GO:0016324=IDA, GO:0030184=IDA, GO:0030185=IDA, GO:0015250=EXP, GO:0042476=IEP, GO:0005372=IDA, GO:0006813=ISS, GO:0071805=IMP, GO:0043066=IDA, GO:0019725=IDA, GO:0042493=IDA, GO:0022857=IDA, GO:0071456=IDA, GO:0045177=IDA, GO:0015670=IDA, GO:0055085=TAS, GO:0045766=IMP, GO:0005903=IDA, GO:0042383=IDA, GO:0015168=IDA, GO:0021670=IEP, GO:0050891=IEP, GO:0051739=IDA, GO:0003097=IDA, GO:0033326=IEP, GO:0016021=IEA, GO:0071260=IDA, GO:0071320=IDA, GO:0071549=IDA} ammonium transport, bicarbonate transport, cGMP biosynthetic process, carbon dioxide transmembrane transport, carbon dioxide transport, cell volume homeostasis, cellular homeostasis, cellular hyperosmotic response, cellular response to UV, cellular response to cAMP, cellular response to copper ion, cellular response to dexamethasone stimulus, cellular response to hydrogen peroxide, cellular response to hypoxia, cellular response to inorganic substance, cellular response to mechanical stimulus, cellular response to mercury ion, cellular response to nitric oxide, cellular response to retinoic acid, cellular response to salt stress, cellular response to stress, cerebrospinal fluid secretion, establishment or maintenance of actin cytoskeleton polarity, glycerol transport, lateral ventricle development, maintenance of symbiont-containing vacuole by host, multicellular organismal water homeostasis, negative regulation of apoptotic process, nitric oxide transport, odontogenesis, pancreatic juice secretion, positive regulation of angiogenesis, positive regulation of fibroblast proliferation, positive regulation of saliva secretion, potassium ion transmembrane transport, potassium ion transport, renal water transport, response to drug, small molecule metabolic process, transepithelial water transport, transmembrane transport, water transport apical part of cell, apical plasma membrane, basal plasma membrane, basolateral plasma membrane, brush border, brush border membrane, cytoplasm, integral to membrane, integral to plasma membrane, nuclear membrane, nucleus, plasma membrane, sarcolemma, symbiont-containing vacuole, symbiont-containing vacuole membrane ammonia transmembrane transporter activity, carbon dioxide transmembrane transporter activity, glycerol transmembrane transporter activity, intracellular cGMP activated cation channel activity, nitric oxide transmembrane transporter activity, potassium channel activity, potassium ion transmembrane transporter activity, protein binding, transmembrane transporter activity, transporter activity, water channel activity, water transmembrane transporter activity Human AQP11 Reactome UniProtKB {GO:0005215=GO_REF:0000002, GO:0005886=Reactome:REACT_23858, GO:0009986=PMID:16650285, GO:0001822=GO_REF:0000019, GO:0005783=GO_REF:0000019, GO:0055085=Reactome:REACT_15518, GO:0030425=GO_REF:0000019, GO:0015840=PMID:16650285, GO:0005829=GO_REF:0000019, GO:0003674=GO_REF:0000015, GO:0048388=GO_REF:0000019, GO:0015793=PMID:16650285, GO:0051260=GO_REF:0000019, GO:0016021=GO_REF:0000037, GO:0006833=Reactome:REACT_23887, GO:0006811=PMID:16650285} Q8NBQ7 Aquaporin-11 protein 20090808 {GO:0005215=IEA, GO:0005886=TAS, GO:0009986=IDA, GO:0001822=IEA, GO:0005783=IEA, GO:0055085=TAS, GO:0030425=IEA, GO:0015840=IDA, GO:0005829=IEA, GO:0003674=ND, GO:0048388=IEA, GO:0015793=IDA, GO:0051260=IEA, GO:0016021=IEA, GO:0006833=TAS, GO:0006811=IDA} endosomal lumen acidification, glycerol transport, ion transport, kidney development, protein homooligomerization, transmembrane transport, urea transport, water transport cell surface, cytosol, dendrite, endoplasmic reticulum, integral to membrane, plasma membrane molecular_function, transporter activity Human AQP2 Reactome UniProtKB {GO:0005802=GO_REF:0000019, GO:0071280=PMID:8584435, GO:0005215=GO_REF:0000002, GO:0009651=GO_REF:0000019, GO:0005886=Reactome:REACT_23863, GO:0051928=GO_REF:0000019, GO:0030136=GO_REF:0000019, GO:0005764=GO_REF:0000019, GO:0006884=GO_REF:0000019, GO:0016323=GO_REF:0000039, GO:0016324=GO_REF:0000024, GO:0042594=GO_REF:0000019, GO:0033762=GO_REF:0000019, GO:0015250=Reactome:REACT_23788, GO:0015793=PMID:8584435, GO:0005372=PMID:9321919, GO:0032496=GO_REF:0000019, GO:0030042=GO_REF:0000019, GO:0006833=Reactome:REACT_24023, GO:0030658=Reactome:REACT_23863, GO:0005791=GO_REF:0000019, GO:0007588=PMID:7532304, GO:0042631=GO_REF:0000019, GO:0007565=GO_REF:0000019, GO:0005794=GO_REF:0000039, GO:0071288=PMID:8584435, GO:0007568=GO_REF:0000019, GO:0006915=GO_REF:0000019, GO:0003779=GO_REF:0000019, GO:0006972=GO_REF:0000019, GO:0030165=GO_REF:0000019, GO:0055085=Reactome:REACT_15518, GO:0072205=GO_REF:0000019, GO:0043234=GO_REF:0000019, GO:0051592=GO_REF:0000019, GO:0015168=PMID:8584435, GO:0010226=GO_REF:0000019, GO:0003097=GO_REF:0000019, GO:0016021=GO_REF:0000037, GO:0055037=GO_REF:0000019, GO:0070382=GO_REF:0000019, GO:0005769=GO_REF:0000019} P41181 Aquaporin-2 protein 20090812 {GO:0005802=IEA, GO:0071280=IDA, GO:0005215=IEA, GO:0009651=IEA, GO:0005886=TAS, GO:0051928=IEA, GO:0030136=IEA, GO:0005764=IEA, GO:0006884=IEA, GO:0016323=IEA, GO:0016324=ISS, GO:0042594=IEA, GO:0033762=IEA, GO:0015250=EXP, GO:0015793=IDA, GO:0005372=IDA, GO:0032496=IEA, GO:0030042=IEA, GO:0006833=TAS, GO:0030658=TAS, GO:0005791=IEA, GO:0007588=TAS, GO:0042631=IEA, GO:0007565=IEA, GO:0005794=IEA, GO:0071288=IDA, GO:0007568=IEA, GO:0006915=IEA, GO:0003779=IEA, GO:0006972=IEA, GO:0030165=IEA, GO:0055085=TAS, GO:0072205=IEA, GO:0043234=IEA, GO:0051592=IEA, GO:0015168=IDA, GO:0010226=IEA, GO:0003097=IEA, GO:0016021=IEA, GO:0055037=IEA, GO:0070382=IEA, GO:0005769=IEA} actin filament depolymerization, aging, apoptotic process, cell volume homeostasis, cellular response to copper ion, cellular response to mercury ion, cellular response to water deprivation, excretion, female pregnancy, glycerol transport, hyperosmotic response, metanephric collecting duct development, positive regulation of calcium ion transport, renal water transport, response to calcium ion, response to glucagon stimulus, response to lipopolysaccharide, response to lithium ion, response to salt stress, response to starvation, transmembrane transport, water transport Golgi apparatus, apical plasma membrane, basolateral plasma membrane, clathrin-coated vesicle, early endosome, exocytic vesicle, integral to membrane, lysosome, plasma membrane, protein complex, recycling endosome, rough endoplasmic reticulum, trans-Golgi network, transport vesicle membrane PDZ domain binding, actin binding, glycerol transmembrane transporter activity, transporter activity, water channel activity, water transmembrane transporter activity Human AQP3 BHF-UCL UniProtKB {GO:0005215=PMID:7543093, GO:0007588=PMID:7543093, GO:0005886=Reactome:REACT_23921, GO:0033280=PMID:17943189, GO:0002684=PMID:17943189, GO:0070295=GO_REF:0000019, GO:0055085=Reactome:REACT_15518, GO:0015840=GO_REF:0000019, GO:0051592=PMID:17943189, GO:0045616=PMID:17943189, GO:0016323=GO_REF:0000039, GO:0005737=PMID:18718702, GO:0005911=PMID:18718702, GO:0015250=PMID:17943189, GO:0042476=PMID:12522663, GO:0006810=PMID:7543093, GO:0016021=PMID:17943189, GO:0015254=PMID:17943189, GO:0032526=PMID:17943189, GO:0006833=PMID:17943189} Q92482 Aquaporin-3 protein 20080625 {GO:0005215=NAS, GO:0007588=TAS, GO:0005886=TAS, GO:0033280=TAS, GO:0002684=IDA, GO:0070295=IEA, GO:0055085=TAS, GO:0015840=IEA, GO:0051592=TAS, GO:0045616=TAS, GO:0016323=IEA, GO:0005737=IDA, GO:0005911=IDA, GO:0015250=TAS, GO:0042476=IEP, GO:0006810=NAS, GO:0016021=IC, GO:0015254=IDA, GO:0032526=IDA, GO:0006833=TAS} excretion, odontogenesis, positive regulation of immune system process, regulation of keratinocyte differentiation, renal water absorption, response to calcium ion, response to retinoic acid, response to vitamin D, transmembrane transport, transport, urea transport, water transport basolateral plasma membrane, cell-cell junction, cytoplasm, integral to membrane, plasma membrane glycerol channel activity, transporter activity, water channel activity Human AQP4 Reactome UniProtKB {GO:0005215=GO_REF:0000002, GO:0005886=Reactome:REACT_24005, GO:0007605=GO_REF:0000019, GO:0070295=GO_REF:0000019, GO:0016323=GO_REF:0000019, GO:0005737=PMID:18392839, GO:0005911=GO_REF:0000019, GO:0071392=GO_REF:0000019, GO:0015250=Reactome:REACT_24005, GO:0006810=PMID:7559426, GO:0005372=PMID:7559426, GO:0051260=GO_REF:0000019, GO:0006833=Reactome:REACT_24023, GO:0009314=GO_REF:0000019, GO:0007588=PMID:7528931, GO:0007565=GO_REF:0000019, GO:0030315=GO_REF:0000019, GO:0042538=GO_REF:0000019, GO:0051384=GO_REF:0000019, GO:0015670=GO_REF:0000019, GO:0055085=Reactome:REACT_15518, GO:0007399=PMID:7528931, GO:0043234=GO_REF:0000019, GO:0071346=PMID:17645239, GO:0005887=GO_REF:0000019, GO:0050891=PMID:16814974, GO:0015288=GO_REF:0000019, GO:0016021=GO_REF:0000038, GO:0009897=PMID:17645239} P55087 Aquaporin-4 protein 20090808 {GO:0005215=IEA, GO:0005886=TAS, GO:0007605=IEA, GO:0070295=IEA, GO:0016323=IEA, GO:0005737=IDA, GO:0005911=IEA, GO:0071392=IEA, GO:0015250=EXP, GO:0006810=TAS, GO:0005372=TAS, GO:0051260=IEA, GO:0006833=TAS, GO:0009314=IEA, GO:0007588=TAS, GO:0007565=IEA, GO:0030315=IEA, GO:0042538=IEA, GO:0051384=IEA, GO:0015670=IEA, GO:0055085=TAS, GO:0007399=TAS, GO:0043234=IEA, GO:0071346=IDA, GO:0005887=IEA, GO:0050891=IEP, GO:0015288=IEA, GO:0016021=IEA, GO:0009897=IDA} carbon dioxide transport, cellular response to estradiol stimulus, cellular response to interferon-gamma, excretion, female pregnancy, hyperosmotic salinity response, multicellular organismal water homeostasis, nervous system development, protein homooligomerization, renal water absorption, response to glucocorticoid stimulus, response to radiation, sensory perception of sound, transmembrane transport, transport, water transport T-tubule, basolateral plasma membrane, cell-cell junction, cytoplasm, external side of plasma membrane, integral to membrane, integral to plasma membrane, plasma membrane, protein complex porin activity, transporter activity, water channel activity, water transmembrane transporter activity Human AQP5 IntAct UniProtKB {GO:0005515=PMID:19060904, GO:0007588=PMID:8621489, GO:0005886=Reactome:REACT_23858, GO:0005783=GO_REF:0000019, GO:0048593=GO_REF:0000019, GO:0030157=PMID:12801959, GO:0015670=PMID:19273840, GO:0055085=Reactome:REACT_15518, GO:0005902=GO_REF:0000019, GO:0016324=PMID:12801959, GO:0009925=GO_REF:0000019, GO:0005887=PMID:8621489, GO:0015250=PMID:12801959, GO:0042476=PMID:12522663, GO:0006833=Reactome:REACT_23887, GO:0046541=GO_REF:0000019} P55064 Aquaporin-5 protein 20130415 {GO:0005515=IPI, GO:0007588=TAS, GO:0005886=TAS, GO:0005783=IEA, GO:0048593=IEA, GO:0030157=IEP, GO:0015670=IDA, GO:0055085=TAS, GO:0005902=IEA, GO:0016324=IDA, GO:0009925=IEA, GO:0005887=TAS, GO:0015250=IDA, GO:0042476=IEP, GO:0006833=TAS, GO:0046541=IEA} camera-type eye morphogenesis, carbon dioxide transport, excretion, odontogenesis, pancreatic juice secretion, saliva secretion, transmembrane transport, water transport apical plasma membrane, basal plasma membrane, endoplasmic reticulum, integral to plasma membrane, microvillus, plasma membrane protein binding, water channel activity Human UniProtKB:Q99750 AQP9 GOC UniProtKB {GO:0005886=Reactome:REACT_23966, GO:0006863=PMID:9733774, GO:0005275=PMID:9733774, GO:0043231=PMID:18718702, GO:0016323=GO_REF:0000019, GO:0030104=PMID:9733774, GO:0006955=PMID:9514918, GO:0046942=PMID:9733774, GO:0046943=PMID:9733774, GO:0005350=PMID:9733774, GO:0015791=PMID:9733774, GO:0015793=Reactome:REACT_23809, GO:0015250=PMID:9733774, GO:0015837=PMID:9733774, GO:0006810=PMID:9733774, GO:0005372=PMID:9733774, GO:0015254=Reactome:REACT_23966, GO:0006833=Reactome:REACT_23887, GO:0015855=PMID:9733774, GO:0007588=PMID:9733774, GO:0010033=PMID:9733774, GO:0006970=PMID:9733774, GO:0055085=Reactome:REACT_15518, GO:0072531=PMID:9733774, GO:0005887=PMID:9514918, GO:0015166=PMID:9733774, GO:0015722=GO_REF:0000019, GO:0008152=PMID:9733774, GO:0005345=PMID:9733774, GO:0015288=PMID:9733774, GO:0016021=PMID:9733774, GO:0071320=PMID:17636236, GO:0046689=PMID:9733774} O43315 Aquaporin-9 protein 20130413 {GO:0005886=TAS, GO:0006863=IDA, GO:0005275=TAS, GO:0043231=IDA, GO:0016323=IEA, GO:0030104=NAS, GO:0006955=TAS, GO:0046942=TAS, GO:0046943=TAS, GO:0005350=IDA, GO:0015791=IDA, GO:0015793=TAS, GO:0015250=IDA, GO:0015837=IDA, GO:0006810=TAS, GO:0005372=TAS, GO:0015254=EXP, GO:0006833=TAS, GO:0015855=IDA, GO:0007588=TAS, GO:0010033=IDA, GO:0006970=TAS, GO:0055085=TAS, GO:0072531=IDA, GO:0005887=TAS, GO:0015166=TAS, GO:0015722=IEA, GO:0008152=TAS, GO:0005345=IDA, GO:0015288=NAS, GO:0016021=NAS, GO:0071320=IEP, GO:0046689=IDA} amine transport, canalicular bile acid transport, carboxylic acid transport, cellular response to cAMP, excretion, glycerol transport, immune response, metabolic process, polyol transport, purine nucleobase transport, pyrimidine nucleobase transport, pyrimidine-containing compound transmembrane transport, response to mercury ion, response to organic substance, response to osmotic stress, transmembrane transport, transport, water homeostasis, water transport basolateral plasma membrane, integral to membrane, integral to plasma membrane, intracellular membrane-bounded organelle, plasma membrane amine transmembrane transporter activity, carboxylic acid transmembrane transporter activity, glycerol channel activity, polyol transmembrane transporter activity, porin activity, purine nucleobase transmembrane transporter activity, pyrimidine nucleobase transmembrane transporter activity, water channel activity, water transmembrane transporter activity Human AQR UniProtKB UniProtKB {GO:0000398=PMID:11991638, GO:0005681=GO_REF:0000002, GO:0071013=PMID:11991638, GO:0097157=GO_REF:0000002} O60306 Intron-binding protein aquarius protein 20110302 {GO:0000398=IC, GO:0005681=IEA, GO:0071013=IDA, GO:0097157=IEA} mRNA splicing, via spliceosome catalytic step 2 spliceosome, spliceosomal complex pre-mRNA intronic binding Human GO:0071013 AR BHF-UCL UniProtKB {GO:0005515=PMID:18487222, GO:0010467=Reactome:REACT_71, GO:0008219=GO_REF:0000037, GO:0000790=PMID:17505061, GO:0004882=PMID:12799378, GO:0006367=Reactome:REACT_15525, GO:0003700=PMID:11477070, GO:0008013=PMID:12799378, GO:0044212=PMID:18487222, GO:0050680=GO_REF:0000019, GO:0060571=GO_REF:0000019, GO:0050681=GO_REF:0000019, GO:0051259=PMID:18468998, GO:0048645=GO_REF:0000019, GO:0006810=PMID:10835690, GO:0046983=PMID:10075738, GO:0048808=GO_REF:0000019, GO:0007548=PMID:10075738, GO:0004879=PMID:17277772, GO:0005497=PMID:10075738, GO:0005496=GO_REF:0000002, GO:0032868=GO_REF:0000019, GO:0060685=GO_REF:0000019, GO:0001701=GO_REF:0000019, GO:0003073=GO_REF:0000019, GO:0043234=PMID:18468998, GO:0048638=GO_REF:0000019, GO:0016049=PMID:15572661, GO:0005654=Reactome:REACT_19207, GO:0033148=GO_REF:0000019, GO:0008270=GO_REF:0000002, GO:0019899=PMID:17277772, GO:0045893=PMID:12799378, GO:0008134=PMID:12799378, GO:0030424=GO_REF:0000019, GO:0008284=PMID:17277772, GO:0060736=GO_REF:0000019, GO:0005886=GO_REF:0000019, GO:0008283=PMID:10075738, GO:0007267=PMID:10835690, GO:0005634=PMID:19345326, GO:0060599=GO_REF:0000019, GO:0030425=GO_REF:0000019, GO:0005737=PMID:15572661, GO:0051092=PMID:21310825, GO:0060520=GO_REF:0000019, GO:0045944=PMID:17505061, GO:0001085=PMID:16120611, GO:0045945=PMID:18487222, GO:0030850=PMID:10075738, GO:0060748=GO_REF:0000019, GO:0045720=PMID:21310825, GO:0043066=PMID:21310825, GO:0060742=GO_REF:0000019, GO:0060740=GO_REF:0000019, GO:0005102=PMID:11875111, GO:0045726=PMID:21310825, GO:0003677=PMID:10075738, GO:0070974=GO_REF:0000019, GO:0006351=PMID:15572661, GO:0043565=GO_REF:0000019, GO:0019102=GO_REF:0000019, GO:0007165=PMID:10835690, GO:0050790=GO_REF:0000019, GO:0043568=GO_REF:0000019, GO:0003682=PMID:21730289, GO:0043410=GO_REF:0000019, GO:0030522=PMID:17277772, GO:0090003=PMID:21310825, GO:0030521=PMID:19886863, GO:0008584=GO_REF:0000019, GO:0060749=GO_REF:0000019, GO:0042327=PMID:21310825} P10275 Androgen receptor protein 20120516 {GO:0005515=IPI, GO:0010467=TAS, GO:0008219=IEA, GO:0000790=IDA, GO:0004882=IDA, GO:0006367=TAS, GO:0003700=IDA, GO:0008013=IDA, GO:0044212=IDA, GO:0050680=IEA, GO:0060571=IEA, GO:0050681=IEA, GO:0051259=IDA, GO:0048645=IEA, GO:0006810=TAS, GO:0046983=NAS, GO:0048808=IEA, GO:0007548=NAS, GO:0004879=IDA, GO:0005497=NAS, GO:0005496=IEA, GO:0032868=IEA, GO:0060685=IEA, GO:0001701=IEA, GO:0003073=IEA, GO:0043234=IDA, GO:0048638=IEA, GO:0016049=NAS, GO:0005654=TAS, GO:0033148=IEA, GO:0008270=IEA, GO:0019899=IPI, GO:0045893=IDA, GO:0008134=IPI, GO:0030424=IEA, GO:0008284=IDA, GO:0060736=IEA, GO:0005886=IEA, GO:0008283=NAS, GO:0007267=TAS, GO:0005634=IDA, GO:0060599=IEA, GO:0030425=IEA, GO:0005737=IDA, GO:0051092=IMP, GO:0060520=IEA, GO:0045944=IDA, GO:0001085=IPI, GO:0045945=IDA, GO:0030850=NAS, GO:0060748=IEA, GO:0045720=IDA, GO:0043066=IDA, GO:0060742=IEA, GO:0060740=IEA, GO:0005102=IPI, GO:0045726=IDA, GO:0003677=NAS, GO:0070974=IEA, GO:0006351=IDA, GO:0043565=IEA, GO:0019102=IEA, GO:0007165=TAS, GO:0050790=IEA, GO:0043568=IEA, GO:0003682=IDA, GO:0043410=IEA, GO:0030522=IDA, GO:0090003=IDA, GO:0030521=IDA, GO:0008584=IEA, GO:0060749=IEA, GO:0042327=IMP} activation of prostate induction by androgen receptor signaling pathway, androgen receptor signaling pathway, cell death, cell growth, cell proliferation, cell-cell signaling, epithelial cell differentiation involved in prostate gland development, gene expression, in utero embryonic development, intracellular receptor signaling pathway, lateral sprouting involved in mammary gland duct morphogenesis, male genitalia morphogenesis, male gonad development, male somatic sex determination, mammary gland alveolus development, morphogenesis of an epithelial fold, negative regulation of apoptotic process, negative regulation of epithelial cell proliferation, negative regulation of integrin biosynthetic process, organ formation, positive regulation of MAPK cascade, positive regulation of NF-kappaB transcription factor activity, positive regulation of cell proliferation, positive regulation of insulin-like growth factor receptor signaling pathway, positive regulation of integrin biosynthetic process, positive regulation of intracellular estrogen receptor signaling pathway, positive regulation of phosphorylation, positive regulation of transcription from RNA polymerase II promoter, positive regulation of transcription from RNA polymerase III promoter, positive regulation of transcription, DNA-dependent, prostate gland development, prostate gland epithelium morphogenesis, prostate gland growth, protein oligomerization, regulation of catalytic activity, regulation of developmental growth, regulation of establishment of protein localization to plasma membrane, regulation of prostatic bud formation, regulation of systemic arterial blood pressure, response to insulin stimulus, sex differentiation, signal transduction, tertiary branching involved in mammary gland duct morphogenesis, transcription initiation from RNA polymerase II promoter, transcription, DNA-dependent, transport axon, cytoplasm, dendrite, nuclear chromatin, nucleoplasm, nucleus, plasma membrane, protein complex DNA binding, POU domain binding, RNA polymerase II transcription factor binding, androgen binding, androgen receptor activity, androgen receptor binding, beta-catenin binding, chromatin binding, enzyme binding, ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity, protein binding, protein dimerization activity, receptor binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, steroid binding, transcription factor binding, transcription regulatory region DNA binding, zinc ion binding Human UniProtKB:O75593 ARAF IntAct UniProtKB {GO:0005515=PMID:22939624, GO:0043066=PMID:19667065, GO:0005575=GO_REF:0000015, GO:0005524=GO_REF:0000029, GO:0046872=GO_REF:0000037, GO:0035556=GO_REF:0000002, GO:0005739=GO_REF:0000019, GO:0033138=PMID:19667065, GO:0004672=PMID:3029685, GO:0016301=GO_REF:0000038, GO:0004674=PMID:19667065, GO:0006468=GO_REF:0000029, GO:0005057=GO_REF:0000002, GO:0006464=PMID:3029685} P10398 Serine/threonine-protein kinase A-Raf protein 20130415 {GO:0005515=IPI, GO:0043066=IDA, GO:0005575=ND, GO:0005524=NAS, GO:0046872=IEA, GO:0035556=IEA, GO:0005739=IEA, GO:0033138=IDA, GO:0004672=TAS, GO:0016301=IEA, GO:0004674=IDA, GO:0006468=NAS, GO:0005057=IEA, GO:0006464=TAS} cellular protein modification process, intracellular signal transduction, negative regulation of apoptotic process, positive regulation of peptidyl-serine phosphorylation, protein phosphorylation cellular_component, mitochondrion ATP binding, kinase activity, metal ion binding, protein binding, protein kinase activity, protein serine/threonine kinase activity, receptor signaling protein activity Human UniProtKB:P08238 ARAP1 IntAct UniProtKB {GO:0005515=PMID:16169070, GO:0051056=Reactome:REACT_11051, GO:0030037=PMID:11804590, GO:0005794=PMID:11804590, GO:0005886=GO_REF:0000039, GO:0007264=Reactome:REACT_11044, GO:0008360=PMID:11804590, GO:0005547=PMID:11804589, GO:0051491=PMID:11804590, GO:0005100=PMID:11804590, GO:0005829=Reactome:REACT_9982, GO:0051497=PMID:11804590, GO:0005622=GO_REF:0000002, GO:0007165=GO_REF:0000002, GO:0008060=PMID:11804590, GO:0005543=GO_REF:0000002, GO:0032312=GO_REF:0000002, GO:0032580=GO_REF:0000039, GO:0043089=PMID:11804590, GO:0008270=GO_REF:0000002, GO:0005096=GO_REF:0000038, GO:0051270=PMID:11804590} Q96P48 Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1 protein 20130415 {GO:0005515=IPI, GO:0051056=TAS, GO:0030037=TAS, GO:0005794=IDA, GO:0005886=IEA, GO:0007264=TAS, GO:0008360=IMP, GO:0005547=IDA, GO:0051491=IMP, GO:0005100=IDA, GO:0005829=TAS, GO:0051497=IMP, GO:0005622=IEA, GO:0007165=IEA, GO:0008060=IDA, GO:0005543=IEA, GO:0032312=IEA, GO:0032580=IEA, GO:0043089=IDA, GO:0008270=IEA, GO:0005096=IEA, GO:0051270=IMP} actin filament reorganization involved in cell cycle, negative regulation of stress fiber assembly, positive regulation of Cdc42 GTPase activity, positive regulation of filopodium assembly, regulation of ARF GTPase activity, regulation of cell shape, regulation of cellular component movement, regulation of small GTPase mediated signal transduction, signal transduction, small GTPase mediated signal transduction Golgi apparatus, Golgi cisterna membrane, cytosol, intracellular, plasma membrane ARF GTPase activator activity, GTPase activator activity, Rho GTPase activator activity, phosphatidylinositol-3,4,5-trisphosphate binding, phospholipid binding, protein binding, zinc ion binding Human UniProtKB:P12956 ARAP2 Reactome UniProtKB {GO:0051056=Reactome:REACT_11051, GO:0008060=GO_REF:0000002, GO:0007264=Reactome:REACT_11044, GO:0032312=GO_REF:0000002, GO:0005547=PMID:11804589, GO:0008270=GO_REF:0000002, GO:0005829=Reactome:REACT_9982} Q8WZ64 Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 2 protein 20130301 {GO:0051056=TAS, GO:0008060=IEA, GO:0007264=TAS, GO:0032312=IEA, GO:0005547=IDA, GO:0008270=IEA, GO:0005829=TAS} regulation of ARF GTPase activity, regulation of small GTPase mediated signal transduction, small GTPase mediated signal transduction cytosol ARF GTPase activator activity, phosphatidylinositol-3,4,5-trisphosphate binding, zinc ion binding Human ARAP3 Reactome UniProtKB {GO:0051056=Reactome:REACT_11051, GO:0030336=GO_REF:0000024, GO:0035021=GO_REF:0000019, GO:0005886=GO_REF:0000039, GO:0007264=Reactome:REACT_11044, GO:0043325=PMID:11804589, GO:0008360=GO_REF:0000024, GO:0035024=GO_REF:0000024, GO:0005547=PMID:11804589, GO:0001726=GO_REF:0000024, GO:0005100=GO_REF:0000024, GO:0030027=GO_REF:0000024, GO:0005829=Reactome:REACT_9982, GO:0005622=GO_REF:0000002, GO:0007165=GO_REF:0000002, GO:0008060=GO_REF:0000024, GO:0005737=PMID:11804589, GO:0005543=GO_REF:0000002, GO:0032312=GO_REF:0000002, GO:0007010=PMID:15569923, GO:0008270=GO_REF:0000002, GO:0016192=PMID:15569923, GO:0005856=GO_REF:0000039, GO:0030675=GO_REF:0000024} Q8WWN8 Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3 protein 20130301 {GO:0051056=TAS, GO:0030336=ISS, GO:0035021=IEA, GO:0005886=IEA, GO:0007264=TAS, GO:0043325=IDA, GO:0008360=ISS, GO:0035024=ISS, GO:0005547=IDA, GO:0001726=ISS, GO:0005100=ISS, GO:0030027=ISS, GO:0005829=TAS, GO:0005622=IEA, GO:0007165=IEA, GO:0008060=ISS, GO:0005737=IC, GO:0005543=IEA, GO:0032312=IEA, GO:0007010=TAS, GO:0008270=IEA, GO:0016192=TAS, GO:0005856=IEA, GO:0030675=ISS} cytoskeleton organization, negative regulation of Rac protein signal transduction, negative regulation of Rho protein signal transduction, negative regulation of cell migration, regulation of ARF GTPase activity, regulation of cell shape, regulation of small GTPase mediated signal transduction, signal transduction, small GTPase mediated signal transduction, vesicle-mediated transport cytoplasm, cytoskeleton, cytosol, intracellular, lamellipodium, plasma membrane, ruffle ARF GTPase activator activity, Rac GTPase activator activity, Rho GTPase activator activity, phosphatidylinositol-3,4,5-trisphosphate binding, phosphatidylinositol-3,4-bisphosphate binding, phospholipid binding, zinc ion binding Human ARC UniProtKB UniProtKB {GO:0030054=GO_REF:0000037, GO:0005886=PMID:21834987, GO:0001669=GO_REF:0000039, GO:0014069=GO_REF:0000039, GO:0009952=GO_REF:0000019, GO:0015629=GO_REF:0000019, GO:0006897=GO_REF:0000037, GO:0005737=PMID:21834987, GO:0007492=GO_REF:0000019, GO:0048168=GO_REF:0000019, GO:0016477=PMID:21834987, GO:0045211=GO_REF:0000037, GO:0022604=PMID:21834987, GO:0007010=PMID:21834987, GO:0007612=GO_REF:0000019, GO:0005768=GO_REF:0000039} Q7LC44 Activity-regulated cytoskeleton-associated protein protein 20110926 {GO:0030054=IEA, GO:0005886=IDA, GO:0001669=IEA, GO:0014069=IEA, GO:0009952=IEA, GO:0015629=IEA, GO:0006897=IEA, GO:0005737=IDA, GO:0007492=IEA, GO:0048168=IEA, GO:0016477=IMP, GO:0045211=IEA, GO:0022604=IMP, GO:0007010=IMP, GO:0007612=IEA, GO:0005768=IEA} anterior/posterior pattern specification, cell migration, cytoskeleton organization, endocytosis, endoderm development, learning, regulation of cell morphogenesis, regulation of neuronal synaptic plasticity acrosomal vesicle, actin cytoskeleton, cell junction, cytoplasm, endosome, plasma membrane, postsynaptic density, postsynaptic membrane Human ARCN1 Reactome UniProtKB {GO:0030131=GO_REF:0000002, GO:0030126=GO_REF:0000024, GO:0006890=Reactome:REACT_11208, GO:0006886=GO_REF:0000002, GO:0048205=Reactome:REACT_11096, GO:0016044=Reactome:REACT_11123, GO:0005829=Reactome:REACT_11243} P48444 Coatomer subunit delta protein 20130213 {GO:0030131=IEA, GO:0030126=ISS, GO:0006890=TAS, GO:0006886=IEA, GO:0048205=TAS, GO:0016044=TAS, GO:0005829=TAS} COPI coating of Golgi vesicle, cellular membrane organization, intracellular protein transport, retrograde vesicle-mediated transport, Golgi to ER COPI vesicle coat, clathrin adaptor complex, cytosol Human AREG BHF-UCL UniProtKB {GO:0009986=PMID:12743035, GO:0007186=PMID:12743035, GO:0007173=PMID:12743035, GO:0008283=PMID:2466334, GO:0045740=PMID:12743035, GO:0007267=PMID:2466334, GO:0016021=GO_REF:0000037, GO:0005615=PMID:12743035, GO:0008083=GO_REF:0000037, GO:0005125=GO_REF:0000037} P15514 Amphiregulin protein 20081121 {GO:0009986=IDA, GO:0007186=IDA, GO:0007173=IDA, GO:0008283=TAS, GO:0045740=IMP, GO:0007267=TAS, GO:0016021=IEA, GO:0005615=IDA, GO:0008083=IEA, GO:0005125=IEA} G-protein coupled receptor signaling pathway, cell proliferation, cell-cell signaling, epidermal growth factor receptor signaling pathway, positive regulation of DNA replication cell surface, extracellular space, integral to membrane cytokine activity, growth factor activity Human ARF1 GOC UniProtKB {GO:0005515=PMID:14654833, GO:0048471=GO_REF:0000039, GO:0005886=PMID:8529647, GO:0006661=Reactome:REACT_120836, GO:0007264=GO_REF:0000002, GO:0006890=Reactome:REACT_11208, GO:0006892=Reactome:REACT_11235, GO:0003924=PMID:1577740, GO:0044281=Reactome:REACT_111217, GO:0005525=GO_REF:0000037, GO:0015031=GO_REF:0000037, GO:0030017=GO_REF:0000019, GO:0048205=Reactome:REACT_11096, GO:0050690=Reactome:REACT_11166, GO:0005829=Reactome:REACT_121003, GO:0006184=PMID:1577740, GO:0019886=Reactome:REACT_121399, GO:0006878=PMID:21034850, GO:0000139=Reactome:REACT_121296, GO:0016032=Reactome:REACT_6185, GO:0005057=PMID:8529647, GO:0006644=Reactome:REACT_121175, GO:0016044=Reactome:REACT_11123} P84077 ADP-ribosylation factor 1 protein 20130413 {GO:0005515=IPI, GO:0048471=IEA, GO:0005886=TAS, GO:0006661=TAS, GO:0007264=IEA, GO:0006890=TAS, GO:0006892=TAS, GO:0003924=TAS, GO:0044281=TAS, GO:0005525=IEA, GO:0015031=IEA, GO:0030017=IEA, GO:0048205=TAS, GO:0050690=TAS, GO:0005829=TAS, GO:0006184=TAS, GO:0019886=TAS, GO:0006878=IMP, GO:0000139=TAS, GO:0016032=TAS, GO:0005057=TAS, GO:0006644=TAS, GO:0016044=TAS} COPI coating of Golgi vesicle, GTP catabolic process, antigen processing and presentation of exogenous peptide antigen via MHC class II, cellular copper ion homeostasis, cellular membrane organization, phosphatidylinositol biosynthetic process, phospholipid metabolic process, post-Golgi vesicle-mediated transport, protein transport, regulation of defense response to virus by virus, retrograde vesicle-mediated transport, Golgi to ER, small GTPase mediated signal transduction, small molecule metabolic process, viral reproduction Golgi membrane, cytosol, perinuclear region of cytoplasm, plasma membrane, sarcomere GTP binding, GTPase activity, protein binding, receptor signaling protein activity Human ARF3 GOC UniProtKB {GO:0048471=GO_REF:0000039, GO:0005794=GO_REF:0000019, GO:0006661=Reactome:REACT_120836, GO:0007264=GO_REF:0000002, GO:0003924=PMID:1744102, GO:0044281=Reactome:REACT_111217, GO:0005525=GO_REF:0000037, GO:0015031=GO_REF:0000037, GO:0005622=GO_REF:0000002, GO:0006184=PMID:1744102, GO:0000139=Reactome:REACT_121296, GO:0016192=GO_REF:0000037, GO:0006644=Reactome:REACT_121175} P61204 ADP-ribosylation factor 3 protein 20130413 {GO:0048471=IEA, GO:0005794=IEA, GO:0006661=TAS, GO:0007264=IEA, GO:0003924=TAS, GO:0044281=TAS, GO:0005525=IEA, GO:0015031=IEA, GO:0005622=IEA, GO:0006184=TAS, GO:0000139=TAS, GO:0016192=IEA, GO:0006644=TAS} GTP catabolic process, phosphatidylinositol biosynthetic process, phospholipid metabolic process, protein transport, small GTPase mediated signal transduction, small molecule metabolic process, vesicle-mediated transport Golgi apparatus, Golgi membrane, intracellular, perinuclear region of cytoplasm GTP binding, GTPase activity Human ARF4 GOC UniProtKB {GO:0005515=PMID:21988832, GO:0005794=GO_REF:0000039, GO:0005886=GO_REF:0000019, GO:0007264=GO_REF:0000002, GO:0003924=PMID:2107548, GO:0005525=GO_REF:0000037, GO:0015031=GO_REF:0000037, GO:0048678=GO_REF:0000019, GO:0006184=PMID:2107548, GO:0005622=GO_REF:0000002, GO:0005737=GO_REF:0000019, GO:0007173=GO_REF:0000019, GO:0007420=GO_REF:0000019, GO:0016192=GO_REF:0000037} P18085 ADP-ribosylation factor 4 protein 20130413 {GO:0005515=IPI, GO:0005794=IEA, GO:0005886=IEA, GO:0007264=IEA, GO:0003924=TAS, GO:0005525=IEA, GO:0015031=IEA, GO:0048678=IEA, GO:0006184=TAS, GO:0005622=IEA, GO:0005737=IEA, GO:0007173=IEA, GO:0007420=IEA, GO:0016192=IEA} GTP catabolic process, brain development, epidermal growth factor receptor signaling pathway, protein transport, response to axon injury, small GTPase mediated signal transduction, vesicle-mediated transport Golgi apparatus, cytoplasm, intracellular, plasma membrane GTP binding, GTPase activity, protein binding Human ARF5 GOC UniProtKB {GO:0006184=PMID:1993656, GO:0005515=PMID:17030804, GO:0005622=GO_REF:0000002, GO:0048471=GO_REF:0000039, GO:0005794=GO_REF:0000039, GO:0005886=GO_REF:0000019, GO:0007264=GO_REF:0000002, GO:0003924=PMID:1993656, GO:0016192=GO_REF:0000037, GO:0015031=GO_REF:0000037, GO:0005525=GO_REF:0000037} P84085 ADP-ribosylation factor 5 protein 20130413 {GO:0006184=TAS, GO:0005515=IPI, GO:0005622=IEA, GO:0048471=IEA, GO:0005794=IEA, GO:0005886=IEA, GO:0007264=IEA, GO:0003924=TAS, GO:0016192=IEA, GO:0015031=IEA, GO:0005525=IEA} GTP catabolic process, protein transport, small GTPase mediated signal transduction, vesicle-mediated transport Golgi apparatus, intracellular, perinuclear region of cytoplasm, plasma membrane GTP binding, GTPase activity, protein binding Human ARF6 GOC UniProtKB {GO:0090162=GO_REF:0000019, GO:0005515=PMID:16415858, GO:0035020=PMID:10036235, GO:0005886=PMID:19948740, GO:0007264=GO_REF:0000002, GO:0003924=PMID:1993656, GO:0031527=PMID:14978216, GO:0006928=PMID:10036235, GO:0030139=PMID:19948740, GO:0031996=PMID:15509780, GO:0015031=GO_REF:0000037, GO:0031529=PMID:10036235, GO:0051489=PMID:14978216, GO:0030838=PMID:10036235, GO:0016192=PMID:10913182, GO:0007155=PMID:10036235, GO:0060998=GO_REF:0000024, GO:0005938=PMID:10913182, GO:0005794=GO_REF:0000039, GO:0006915=GO_REF:0000019, GO:0005525=PMID:10913182, GO:0001726=PMID:9312003, GO:0006184=PMID:1993656, GO:0001889=GO_REF:0000019, GO:0016020=PMID:8702973, GO:0030866=PMID:10913182, GO:0034394=GO_REF:0000024, GO:0048261=PMID:9312003, GO:0055037=GO_REF:0000019, GO:0010008=GO_REF:0000039, GO:0005769=GO_REF:0000019, GO:0090004=GO_REF:0000024, GO:0005768=PMID:20682791} P62330 ADP-ribosylation factor 6 protein 20130413 {GO:0090162=IEA, GO:0005515=IPI, GO:0035020=IDA, GO:0005886=IDA, GO:0007264=IEA, GO:0003924=TAS, GO:0031527=IDA, GO:0006928=TAS, GO:0030139=IDA, GO:0031996=IPI, GO:0015031=IEA, GO:0031529=IDA, GO:0051489=IDA, GO:0030838=IMP, GO:0016192=TAS, GO:0007155=TAS, GO:0060998=ISS, GO:0005938=IDA, GO:0005794=IEA, GO:0006915=IEA, GO:0005525=TAS, GO:0001726=IDA, GO:0006184=TAS, GO:0001889=IEA, GO:0016020=TAS, GO:0030866=IMP, GO:0034394=ISS, GO:0048261=TAS, GO:0055037=IEA, GO:0010008=IEA, GO:0005769=IEA, GO:0090004=ISS, GO:0005768=IDA} GTP catabolic process, apoptotic process, cell adhesion, cellular component movement, cortical actin cytoskeleton organization, establishment of epithelial cell polarity, liver development, negative regulation of receptor-mediated endocytosis, positive regulation of actin filament polymerization, positive regulation of establishment of protein localization to plasma membrane, protein localization to cell surface, protein transport, regulation of Rac protein signal transduction, regulation of dendritic spine development, regulation of filopodium assembly, ruffle organization, small GTPase mediated signal transduction, vesicle-mediated transport Golgi apparatus, cell cortex, early endosome, endocytic vesicle, endosome, endosome membrane, filopodium membrane, membrane, plasma membrane, recycling endosome, ruffle GTP binding, GTPase activity, protein binding, thioesterase binding Human ARFGAP1 HPA UniProtKB {GO:0031965=GO_REF:0000052, GO:0005886=GO_REF:0000052, GO:0005783=GO_REF:0000052, GO:0006890=Reactome:REACT_11208, GO:0045202=GO_REF:0000019, GO:0015031=GO_REF:0000037, GO:0048205=Reactome:REACT_11096, GO:0030968=Reactome:REACT_18356, GO:0043231=GO_REF:0000052, GO:0005829=Reactome:REACT_115613, GO:0043547=PMID:22423108, GO:0008060=GO_REF:0000002, GO:0000139=GO_REF:0000019, GO:0032312=GO_REF:0000002, GO:0030660=Reactome:REACT_11138, GO:0008270=GO_REF:0000002, GO:0006987=Reactome:REACT_18368, GO:0044267=Reactome:REACT_17015, GO:0016044=Reactome:REACT_11123, GO:0005096=PMID:22423108} Q8N6T3 ADP-ribosylation factor GTPase-activating protein 1 protein 20120912 {GO:0031965=IDA, GO:0005886=IDA, GO:0005783=IDA, GO:0006890=TAS, GO:0045202=IEA, GO:0015031=IEA, GO:0048205=TAS, GO:0030968=TAS, GO:0043231=IDA, GO:0005829=TAS, GO:0043547=IDA, GO:0008060=IEA, GO:0000139=IEA, GO:0032312=IEA, GO:0030660=TAS, GO:0008270=IEA, GO:0006987=TAS, GO:0044267=TAS, GO:0016044=TAS, GO:0005096=IDA} COPI coating of Golgi vesicle, activation of signaling protein activity involved in unfolded protein response, cellular membrane organization, cellular protein metabolic process, endoplasmic reticulum unfolded protein response, positive regulation of GTPase activity, protein transport, regulation of ARF GTPase activity, retrograde vesicle-mediated transport, Golgi to ER Golgi membrane, Golgi-associated vesicle membrane, cytosol, endoplasmic reticulum, intracellular membrane-bounded organelle, nuclear membrane, plasma membrane, synapse ARF GTPase activator activity, GTPase activator activity, zinc ion binding Human ARFGAP2 HPA UniProtKB {GO:0008060=GO_REF:0000002, GO:0005737=GO_REF:0000052, GO:0005794=GO_REF:0000052, GO:0000139=GO_REF:0000039, GO:0005886=GO_REF:0000052, GO:0032312=GO_REF:0000002, GO:0005730=GO_REF:0000052, GO:0008270=GO_REF:0000002, GO:0016192=GO_REF:0000037, GO:0015031=GO_REF:0000037} Q8N6H7 ADP-ribosylation factor GTPase-activating protein 2 protein 20101115 {GO:0008060=IEA, GO:0005737=IDA, GO:0005794=IDA, GO:0000139=IEA, GO:0005886=IDA, GO:0032312=IEA, GO:0005730=IDA, GO:0008270=IEA, GO:0016192=IEA, GO:0015031=IEA} protein transport, regulation of ARF GTPase activity, vesicle-mediated transport Golgi apparatus, Golgi membrane, cytoplasm, nucleolus, plasma membrane ARF GTPase activator activity, zinc ion binding Human ARFGAP3 HPA UniProtKB {GO:0008060=PMID:11172815, GO:0005737=GO_REF:0000052, GO:0005794=GO_REF:0000052, GO:0009306=PMID:11172815, GO:0000139=GO_REF:0000039, GO:0032312=GO_REF:0000002, GO:0008565=PMID:11172815, GO:0008270=GO_REF:0000002, GO:0016192=PMID:11172815, GO:0006886=PMID:11172815, GO:0005829=PMID:11172815} Q9NP61 ADP-ribosylation factor GTPase-activating protein 3 protein 20101115 {GO:0008060=IDA, GO:0005737=IDA, GO:0005794=IDA, GO:0009306=IEP, GO:0000139=IEA, GO:0032312=IEA, GO:0008565=NAS, GO:0008270=IEA, GO:0016192=NAS, GO:0006886=NAS, GO:0005829=IDA} intracellular protein transport, protein secretion, regulation of ARF GTPase activity, vesicle-mediated transport Golgi apparatus, Golgi membrane, cytoplasm, cytosol ARF GTPase activator activity, protein transporter activity, zinc ion binding Human ARFGEF1 HPA UniProtKB {GO:0005515=PMID:19020088, GO:0005802=GO_REF:0000024, GO:0034237=PMID:12571360, GO:0048471=PMID:22084092, GO:0034259=PMID:15644318, GO:0090303=PMID:22084092, GO:0090284=PMID:17227842, GO:0005634=GO_REF:0000052, GO:0015031=GO_REF:0000037, GO:0006887=PMID:10212200, GO:0010256=PMID:20360857, GO:0016363=GO_REF:0000039, GO:0005829=PMID:10716990, GO:0005085=PMID:15644318, GO:0005086=GO_REF:0000033, GO:0005737=GO_REF:0000052, GO:0030837=PMID:22084092, GO:0007030=PMID:20360857, GO:0030532=PMID:18292223, GO:0016192=GO_REF:0000033, GO:0005794=GO_REF:0000052, GO:0005730=GO_REF:0000052, GO:2000114=PMID:22084092, GO:0008060=PMID:15644318, GO:0000139=PMID:10716990, GO:0032012=GO_REF:0000002, GO:0017022=PMID:15644318} Q9Y6D6 Brefeldin A-inhibited guanine nucleotide-exchange protein 1 protein 20100326 {GO:0005515=IPI, GO:0005802=ISS, GO:0034237=IDA, GO:0048471=IDA, GO:0034259=IDA, GO:0090303=IMP, GO:0090284=IMP, GO:0005634=IDA, GO:0015031=IEA, GO:0006887=TAS, GO:0010256=IMP, GO:0016363=IEA, GO:0005829=IDA, GO:0005085=IDA, GO:0005086=IBA, GO:0005737=IDA, GO:0030837=IMP, GO:0007030=IMP, GO:0030532=IDA, GO:0016192=IBA, GO:0005794=IDA, GO:0005730=IDA, GO:2000114=IMP, GO:0008060=IDA, GO:0000139=IDA, GO:0032012=IEA, GO:0017022=IPI} Golgi organization, endomembrane system organization, exocytosis, negative regulation of Rho GTPase activity, negative regulation of actin filament polymerization, positive regulation of protein glycosylation in Golgi, positive regulation of wound healing, protein transport, regulation of ARF protein signal transduction, regulation of establishment of cell polarity, vesicle-mediated transport Golgi apparatus, Golgi membrane, cytoplasm, cytosol, nuclear matrix, nucleolus, nucleus, perinuclear region of cytoplasm, small nuclear ribonucleoprotein complex, trans-Golgi network ARF GTPase activator activity, ARF guanyl-nucleotide exchange factor activity, guanyl-nucleotide exchange factor activity, myosin binding, protein binding, protein kinase A regulatory subunit binding Human ARFGEF2 IntAct UniProtKB {GO:0005515=PMID:15705715, GO:0005802=GO_REF:0000024, GO:0034237=PMID:12571360, GO:0048471=GO_REF:0000039, GO:0030054=GO_REF:0000037, GO:0050811=GO_REF:0000024, GO:0006887=GO_REF:0000019, GO:0015031=GO_REF:0000037, GO:0010256=PMID:20360857, GO:0005829=PMID:12571360, GO:0032279=GO_REF:0000024, GO:0035556=PMID:12571360, GO:0005085=PMID:10212200, GO:0005086=PMID:15385626, GO:0001881=PMID:16477018, GO:0032280=GO_REF:0000024, GO:0043197=GO_REF:0000024, GO:0005879=GO_REF:0000024, GO:0007032=PMID:20360857, GO:0016192=GO_REF:0000033, GO:0005815=PMID:15705715, GO:0032760=PMID:17276987, GO:0006893=PMID:17276987, GO:0031410=GO_REF:0000024, GO:0016020=PMID:12571360, GO:0000139=PMID:12571360, GO:0016023=GO_REF:0000039, GO:0032012=GO_REF:0000002, GO:0017022=GO_REF:0000019, GO:0055037=PMID:15385626} Q9Y6D5 Brefeldin A-inhibited guanine nucleotide-exchange protein 2 protein 20130415 {GO:0005515=IPI, GO:0005802=ISS, GO:0034237=IDA, GO:0048471=IEA, GO:0030054=IEA, GO:0050811=ISS, GO:0006887=IEA, GO:0015031=IEA, GO:0010256=IMP, GO:0005829=IDA, GO:0032279=ISS, GO:0035556=IDA, GO:0005085=IDA, GO:0005086=IDA, GO:0001881=IDA, GO:0032280=ISS, GO:0043197=ISS, GO:0005879=ISS, GO:0007032=IMP, GO:0016192=IBA, GO:0005815=IDA, GO:0032760=IMP, GO:0006893=IMP, GO:0031410=ISS, GO:0016020=IDA, GO:0000139=IDA, GO:0016023=IEA, GO:0032012=IEA, GO:0017022=IEA, GO:0055037=IDA} Golgi to plasma membrane transport, endomembrane system organization, endosome organization, exocytosis, intracellular signal transduction, positive regulation of tumor necrosis factor production, protein transport, receptor recycling, regulation of ARF protein signal transduction, vesicle-mediated transport Golgi membrane, asymmetric synapse, axonemal microtubule, cell junction, cytoplasmic membrane-bounded vesicle, cytoplasmic vesicle, cytosol, dendritic spine, membrane, microtubule organizing center, perinuclear region of cytoplasm, recycling endosome, symmetric synapse, trans-Golgi network ARF guanyl-nucleotide exchange factor activity, GABA receptor binding, guanyl-nucleotide exchange factor activity, myosin binding, protein binding, protein kinase A regulatory subunit binding Human UniProtKB:Q9UPT5-1 ARFIP1 MGI UniProtKB {GO:0003674=GO_REF:0000015, GO:0000139=PMID:9038142, GO:0019904=GO_REF:0000002, GO:0050708=PMID:12606037, GO:0006886=PMID:12606037, GO:0005829=PMID:9038142, GO:0042802=GO_REF:0000019} P53367 Arfaptin-1 protein 20060110 {GO:0003674=ND, GO:0000139=IDA, GO:0019904=IEA, GO:0050708=IDA, GO:0006886=IDA, GO:0005829=IDA, GO:0042802=IEA} intracellular protein transport, regulation of protein secretion Golgi membrane, cytosol identical protein binding, molecular_function, protein domain specific binding Human ARFIP2 IntAct UniProtKB {GO:0005515=PMID:21988832, GO:0030036=PMID:9312003, GO:0005886=PMID:9312003, GO:0007264=PMID:8670882, GO:0019904=GO_REF:0000002, GO:0030032=PMID:9312003, GO:0006928=PMID:8670882, GO:0005525=PMID:8670882, GO:0001726=PMID:8670882, GO:0031529=PMID:9312003, GO:0048365=PMID:9312003, GO:0030742=PMID:9312003, GO:0005737=PMID:9312003, GO:0005938=PMID:9312003} P53365 Arfaptin-2 protein 20130415 {GO:0005515=IPI, GO:0030036=IMP, GO:0005886=TAS, GO:0007264=TAS, GO:0019904=IEA, GO:0030032=TAS, GO:0006928=TAS, GO:0005525=TAS, GO:0001726=IMP, GO:0031529=TAS, GO:0048365=TAS, GO:0030742=IPI, GO:0005737=TAS, GO:0005938=IDA} actin cytoskeleton organization, cellular component movement, lamellipodium assembly, ruffle organization, small GTPase mediated signal transduction cell cortex, cytoplasm, plasma membrane, ruffle GTP binding, GTP-dependent protein binding, Rac GTPase binding, protein binding, protein domain specific binding Human UniProtKB:P63000 ARFRP1 GOC UniProtKB {GO:0005802=PMID:16129887, GO:0005515=PMID:11438518, GO:0007369=GO_REF:0000019, GO:0005794=PMID:19224922, GO:0007264=GO_REF:0000002, GO:0043001=PMID:16129887, GO:0003924=PMID:8530503, GO:0005525=GO_REF:0000037, GO:0006184=PMID:8530503, GO:0007165=PMID:8530503, GO:0016020=GO_REF:0000019, GO:0034067=PMID:19224922, GO:0042147=PMID:16129887} Q13795 ADP-ribosylation factor-related protein 1 protein 20130413 {GO:0005802=IDA, GO:0005515=IPI, GO:0007369=IEA, GO:0005794=IDA, GO:0007264=IEA, GO:0043001=IMP, GO:0003924=TAS, GO:0005525=IEA, GO:0006184=TAS, GO:0007165=TAS, GO:0016020=IEA, GO:0034067=IMP, GO:0042147=IMP} GTP catabolic process, Golgi to plasma membrane protein transport, gastrulation, protein localization to Golgi apparatus, retrograde transport, endosome to Golgi, signal transduction, small GTPase mediated signal transduction Golgi apparatus, membrane, trans-Golgi network GTP binding, GTPase activity, protein binding Human ARG1 Reactome UniProtKB {GO:0043005=GO_REF:0000019, GO:0070301=GO_REF:0000019, GO:0030324=GO_REF:0000019, GO:0033189=GO_REF:0000019, GO:0071560=GO_REF:0000019, GO:0044281=Reactome:REACT_111217, GO:0014075=GO_REF:0000019, GO:0005615=GO_REF:0000019, GO:0048678=GO_REF:0000019, GO:0010043=GO_REF:0000019, GO:0010042=GO_REF:0000019, GO:0005829=Reactome:REACT_394, GO:0034641=Reactome:REACT_13, GO:0070207=GO_REF:0000019, GO:0005737=PMID:3540966, GO:0010963=GO_REF:0000019, GO:0071377=GO_REF:0000019, GO:0043025=GO_REF:0000019, GO:0033197=GO_REF:0000019, GO:0006527=PMID:3540966, GO:0043200=GO_REF:0000019, GO:0030145=GO_REF:0000019, GO:0042493=GO_REF:0000019, GO:0060056=GO_REF:0000019, GO:0060135=GO_REF:0000019, GO:0010269=GO_REF:0000019, GO:0009635=GO_REF:0000019, GO:0001889=GO_REF:0000019, GO:0071222=GO_REF:0000019, GO:0001938=GO_REF:0000019, GO:0051597=GO_REF:0000019, GO:0000050=Reactome:REACT_847, GO:0032964=GO_REF:0000019, GO:0004053=Reactome:REACT_394, GO:0046686=GO_REF:0000019, GO:0071549=GO_REF:0000019} P05089 Arginase-1 protein 20130213 {GO:0043005=IEA, GO:0070301=IEA, GO:0030324=IEA, GO:0033189=IEA, GO:0071560=IEA, GO:0044281=TAS, GO:0014075=IEA, GO:0005615=IEA, GO:0048678=IEA, GO:0010043=IEA, GO:0010042=IEA, GO:0005829=TAS, GO:0034641=TAS, GO:0070207=IEA, GO:0005737=TAS, GO:0010963=IEA, GO:0071377=IEA, GO:0043025=IEA, GO:0033197=IEA, GO:0006527=TAS, GO:0043200=IEA, GO:0030145=IEA, GO:0042493=IEA, GO:0060056=IEA, GO:0060135=IEA, GO:0010269=IEA, GO:0009635=IEA, GO:0001889=IEA, GO:0071222=IEA, GO:0001938=IEA, GO:0051597=IEA, GO:0000050=TAS, GO:0032964=IEA, GO:0004053=EXP, GO:0046686=IEA, GO:0071549=IEA} arginine catabolic process, cellular nitrogen compound metabolic process, cellular response to dexamethasone stimulus, cellular response to glucagon stimulus, cellular response to hydrogen peroxide, cellular response to lipopolysaccharide, cellular response to transforming growth factor beta stimulus, collagen biosynthetic process, liver development, lung development, mammary gland involution, maternal process involved in female pregnancy, positive regulation of endothelial cell proliferation, protein homotrimerization, regulation of L-arginine import, response to amine stimulus, response to amino acid stimulus, response to axon injury, response to cadmium ion, response to drug, response to herbicide, response to manganese ion, response to methylmercury, response to selenium ion, response to vitamin A, response to vitamin E, response to zinc ion, small molecule metabolic process, urea cycle cytoplasm, cytosol, extracellular space, neuron projection, neuronal cell body arginase activity, manganese ion binding Human ARG2 Reactome UniProtKB {GO:0005739=PMID:8898077, GO:0034641=Reactome:REACT_13, GO:0001657=GO_REF:0000019, GO:0005759=Reactome:REACT_21325, GO:0000050=Reactome:REACT_847, GO:0006941=GO_REF:0000019, GO:0006525=GO_REF:0000037, GO:0044281=Reactome:REACT_111217, GO:0004053=Reactome:REACT_21325, GO:0046872=GO_REF:0000037, GO:0006809=PMID:8898077} P78540 Arginase-2, mitochondrial protein 20130213 {GO:0005739=TAS, GO:0034641=TAS, GO:0001657=IEA, GO:0005759=TAS, GO:0000050=TAS, GO:0006941=IEA, GO:0006525=IEA, GO:0044281=TAS, GO:0004053=EXP, GO:0046872=IEA, GO:0006809=TAS} arginine metabolic process, cellular nitrogen compound metabolic process, nitric oxide biosynthetic process, small molecule metabolic process, striated muscle contraction, urea cycle, ureteric bud development mitochondrial matrix, mitochondrion arginase activity, metal ion binding Human ARGLU1 UniProtKB UniProtKB {GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0006351=GO_REF:0000037} Q9NWB6 Arginine and glutamate-rich protein 1 protein 20130413 {GO:0006355=IEA, GO:0005634=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus Human UniProtKB-SubCell:SL-0191 ARHGAP1 HPA UniProtKB {GO:0005515=PMID:16189514, GO:0051056=Reactome:REACT_11051, GO:0017124=GO_REF:0000037, GO:0005886=GO_REF:0000019, GO:0007264=Reactome:REACT_11044, GO:0007266=PMID:8253717, GO:0001726=GO_REF:0000019, GO:0005100=PMID:8288572, GO:0043231=GO_REF:0000052, GO:0005829=Reactome:REACT_9982, GO:0005622=GO_REF:0000002, GO:0007165=GO_REF:0000002, GO:0005070=PMID:8253717, GO:0030675=GO_REF:0000019} Q07960 Rho GTPase-activating protein 1 protein 20101115 {GO:0005515=IPI, GO:0051056=TAS, GO:0017124=IEA, GO:0005886=IEA, GO:0007264=TAS, GO:0007266=TAS, GO:0001726=IEA, GO:0005100=IDA, GO:0043231=IDA, GO:0005829=TAS, GO:0005622=IEA, GO:0007165=IEA, GO:0005070=TAS, GO:0030675=IEA} Rho protein signal transduction, regulation of small GTPase mediated signal transduction, signal transduction, small GTPase mediated signal transduction cytosol, intracellular, intracellular membrane-bounded organelle, plasma membrane, ruffle Rac GTPase activator activity, Rho GTPase activator activity, SH3 domain binding, SH3/SH2 adaptor activity, protein binding Human ARHGAP10 UniProtKB UniProtKB {GO:0005515=PMID:11432776, GO:0051056=Reactome:REACT_11051, GO:0043066=GO_REF:0000019, GO:0048471=GO_REF:0000039, GO:0005886=GO_REF:0000039, GO:0007264=Reactome:REACT_11044, GO:0006915=Reactome:REACT_578, GO:0042981=Reactome:REACT_13648, GO:0005100=GO_REF:0000019, GO:0005829=Reactome:REACT_9982, GO:0005622=GO_REF:0000002, GO:0007165=GO_REF:0000002, GO:0005543=GO_REF:0000002, GO:0007010=GO_REF:0000019, GO:0005096=GO_REF:0000038} H0Y8W5 Rho GTPase-activating protein 10 protein 20130413 {GO:0005515=IPI, GO:0051056=TAS, GO:0043066=IEA, GO:0048471=IEA, GO:0005886=IEA, GO:0007264=TAS, GO:0006915=TAS, GO:0042981=TAS, GO:0005100=IEA, GO:0005829=TAS, GO:0005622=IEA, GO:0007165=IEA, GO:0005543=IEA, GO:0007010=IEA, GO:0005096=IEA} apoptotic process, cytoskeleton organization, negative regulation of apoptotic process, regulation of apoptotic process, regulation of small GTPase mediated signal transduction, signal transduction, small GTPase mediated signal transduction cytosol, intracellular, perinuclear region of cytoplasm, plasma membrane GTPase activator activity, Rho GTPase activator activity, phospholipid binding, protein binding Human UniProtKB-KW:KW-0343 ARHGAP11A Reactome UniProtKB {GO:0005622=GO_REF:0000002, GO:0051056=Reactome:REACT_11051, GO:0007165=GO_REF:0000002, GO:0007264=Reactome:REACT_11044, GO:0005829=Reactome:REACT_9982, GO:0005096=GO_REF:0000037} Q6P4F7 Rho GTPase-activating protein 11A protein 20130301 {GO:0005622=IEA, GO:0051056=TAS, GO:0007165=IEA, GO:0007264=TAS, GO:0005829=TAS, GO:0005096=IEA} regulation of small GTPase mediated signal transduction, signal transduction, small GTPase mediated signal transduction cytosol, intracellular GTPase activator activity Human ARHGAP11B Reactome UniProtKB {GO:0051056=Reactome:REACT_11051, GO:0007264=Reactome:REACT_11044, GO:0005829=Reactome:REACT_9982, GO:0005096=GO_REF:0000037} Q3KRB8 Rho GTPase-activating protein 11B protein 20130301 {GO:0051056=TAS, GO:0007264=TAS, GO:0005829=TAS, GO:0005096=IEA} regulation of small GTPase mediated signal transduction, small GTPase mediated signal transduction cytosol GTPase activator activity Human ARHGAP12 Reactome UniProtKB {GO:0005622=GO_REF:0000002, GO:0051056=Reactome:REACT_11051, GO:0007165=GO_REF:0000002, GO:0005543=GO_REF:0000002, GO:0007264=Reactome:REACT_11044, GO:0005829=Reactome:REACT_9982, GO:0005096=GO_REF:0000037} Q8IWW6 Rho GTPase-activating protein 12 protein 20130301 {GO:0005622=IEA, GO:0051056=TAS, GO:0007165=IEA, GO:0005543=IEA, GO:0007264=TAS, GO:0005829=TAS, GO:0005096=IEA} regulation of small GTPase mediated signal transduction, signal transduction, small GTPase mediated signal transduction cytosol, intracellular GTPase activator activity, phospholipid binding Human ARHGAP15 GOC UniProtKB {GO:0005622=GO_REF:0000002, GO:0051056=Reactome:REACT_11051, GO:0007165=GO_REF:0000002, GO:0005543=GO_REF:0000002, GO:0016020=GO_REF:0000039, GO:0007264=Reactome:REACT_11044, GO:0008360=PMID:12650940, GO:0032855=PMID:12650940, GO:0030675=PMID:12650940, GO:0005829=Reactome:REACT_9982} Q53QZ3 Rho GTPase-activating protein 15 protein 20130413 {GO:0005622=IEA, GO:0051056=TAS, GO:0007165=IEA, GO:0005543=IEA, GO:0016020=IEA, GO:0007264=TAS, GO:0008360=IDA, GO:0032855=IDA, GO:0030675=IDA, GO:0005829=TAS} positive regulation of Rac GTPase activity, regulation of cell shape, regulation of small GTPase mediated signal transduction, signal transduction, small GTPase mediated signal transduction cytosol, intracellular, membrane Rac GTPase activator activity, phospholipid binding Human ARHGAP17 IntAct UniProtKB {GO:0005515=PMID:21481793, GO:0051056=Reactome:REACT_11051, GO:0017124=GO_REF:0000037, GO:0005737=GO_REF:0000002, GO:0016020=GO_REF:0000039, GO:0007264=Reactome:REACT_11044, GO:0005923=GO_REF:0000039, GO:0005829=Reactome:REACT_9982, GO:0005096=GO_REF:0000037} Q68EM7 Rho GTPase-activating protein 17 protein 20130415 {GO:0005515=IPI, GO:0051056=TAS, GO:0017124=IEA, GO:0005737=IEA, GO:0016020=IEA, GO:0007264=TAS, GO:0005923=IEA, GO:0005829=TAS, GO:0005096=IEA} regulation of small GTPase mediated signal transduction, small GTPase mediated signal transduction cytoplasm, cytosol, membrane, tight junction GTPase activator activity, SH3 domain binding, protein binding Human UniProtKB:Q4VCS5-2 ARHGAP18 Reactome UniProtKB {GO:0051056=Reactome:REACT_11051, GO:0007264=Reactome:REACT_11044, GO:0005829=Reactome:REACT_9982, GO:0005096=GO_REF:0000037} Q8N392 Rho GTPase-activating protein 18 protein 20130301 {GO:0051056=TAS, GO:0007264=TAS, GO:0005829=TAS, GO:0005096=IEA} regulation of small GTPase mediated signal transduction, small GTPase mediated signal transduction cytosol GTPase activator activity Human ARHGAP19 Reactome UniProtKB {GO:0005622=GO_REF:0000002, GO:0051056=Reactome:REACT_11051, GO:0007165=GO_REF:0000002, GO:0007264=Reactome:REACT_11044, GO:0005634=GO_REF:0000039, GO:0005829=Reactome:REACT_9982, GO:0005096=GO_REF:0000037} Q14CB8 Rho GTPase-activating protein 19 protein 20130301 {GO:0005622=IEA, GO:0051056=TAS, GO:0007165=IEA, GO:0007264=TAS, GO:0005634=IEA, GO:0005829=TAS, GO:0005096=IEA} regulation of small GTPase mediated signal transduction, signal transduction, small GTPase mediated signal transduction cytosol, intracellular, nucleus GTPase activator activity Human ARHGAP20 Reactome UniProtKB {GO:0051056=Reactome:REACT_11051, GO:0005543=GO_REF:0000002, GO:0007264=Reactome:REACT_11044, GO:0005829=Reactome:REACT_9982, GO:0005096=GO_REF:0000037} Q9P2F6 Rho GTPase-activating protein 20 protein 20130301 {GO:0051056=TAS, GO:0005543=IEA, GO:0007264=TAS, GO:0005829=TAS, GO:0005096=IEA} regulation of small GTPase mediated signal transduction, small GTPase mediated signal transduction cytosol GTPase activator activity, phospholipid binding Human ARHGAP21 BHF-UCL UniProtKB {GO:0005515=PMID:20195357, GO:0030054=GO_REF:0000039, GO:0005794=PMID:20525016, GO:0072384=PMID:20525016, GO:0051684=PMID:20525016, GO:0051683=PMID:20525016, GO:0005622=GO_REF:0000002, GO:0007165=GO_REF:0000002, GO:0005543=GO_REF:0000002, GO:0000139=GO_REF:0000039, GO:0007030=PMID:20525016, GO:0005856=GO_REF:0000039, GO:0030659=GO_REF:0000039, GO:0005096=GO_REF:0000037} Q5T5U3 Rho GTPase-activating protein 21 protein 20120322 {GO:0005515=IPI, GO:0030054=IEA, GO:0005794=IDA, GO:0072384=IMP, GO:0051684=IMP, GO:0051683=IDA, GO:0005622=IEA, GO:0007165=IEA, GO:0005543=IEA, GO:0000139=IEA, GO:0007030=IMP, GO:0005856=IEA, GO:0030659=IEA, GO:0005096=IEA} Golgi organization, establishment of Golgi localization, maintenance of Golgi location, organelle transport along microtubule, signal transduction Golgi apparatus, Golgi membrane, cell junction, cytoplasmic vesicle membrane, cytoskeleton, intracellular GTPase activator activity, phospholipid binding, protein binding Human ARHGAP22 IntAct UniProtKB {GO:0005515=PMID:21078624, GO:0051056=Reactome:REACT_11051, GO:0006355=GO_REF:0000037, GO:0007264=Reactome:REACT_11044, GO:0005634=GO_REF:0000039, GO:0001525=GO_REF:0000037, GO:0006351=GO_REF:0000037, GO:0030154=GO_REF:0000037, GO:0005829=Reactome:REACT_9982, GO:0005622=GO_REF:0000002, GO:0007165=GO_REF:0000002, GO:0005543=GO_REF:0000002, GO:0005096=GO_REF:0000037} Q7Z5H3 Rho GTPase-activating protein 22 protein 20130415 {GO:0005515=IPI, GO:0051056=TAS, GO:0006355=IEA, GO:0007264=TAS, GO:0005634=IEA, GO:0001525=IEA, GO:0006351=IEA, GO:0030154=IEA, GO:0005829=TAS, GO:0005622=IEA, GO:0007165=IEA, GO:0005543=IEA, GO:0005096=IEA} angiogenesis, cell differentiation, regulation of small GTPase mediated signal transduction, regulation of transcription, DNA-dependent, signal transduction, small GTPase mediated signal transduction, transcription, DNA-dependent cytosol, intracellular, nucleus GTPase activator activity, phospholipid binding, protein binding Human UniProtKB:O00555 ARHGAP23 Reactome UniProtKB {GO:0005622=GO_REF:0000002, GO:0051056=Reactome:REACT_11051, GO:0007165=GO_REF:0000002, GO:0005543=GO_REF:0000002, GO:0007264=Reactome:REACT_11044, GO:0005829=Reactome:REACT_9982, GO:0005096=GO_REF:0000037} Q9P227 Rho GTPase-activating protein 23 protein 20130301 {GO:0005622=IEA, GO:0051056=TAS, GO:0007165=IEA, GO:0005543=IEA, GO:0007264=TAS, GO:0005829=TAS, GO:0005096=IEA} regulation of small GTPase mediated signal transduction, signal transduction, small GTPase mediated signal transduction cytosol, intracellular GTPase activator activity, phospholipid binding Human ARHGAP24 HPA UniProtKB {GO:0051056=Reactome:REACT_11051, GO:0005886=GO_REF:0000052, GO:0007264=Reactome:REACT_11044, GO:0001525=GO_REF:0000037, GO:0042995=GO_REF:0000039, GO:0030154=GO_REF:0000037, GO:0005829=Reactome:REACT_9982, GO:0005622=GO_REF:0000002, GO:0007165=GO_REF:0000002, GO:0005737=GO_REF:0000052, GO:0005543=GO_REF:0000002, GO:0005856=GO_REF:0000039, GO:0005925=GO_REF:0000039, GO:0005096=GO_REF:0000037} Q8N264 Rho GTPase-activating protein 24 protein 20100326 {GO:0051056=TAS, GO:0005886=IDA, GO:0007264=TAS, GO:0001525=IEA, GO:0042995=IEA, GO:0030154=IEA, GO:0005829=TAS, GO:0005622=IEA, GO:0007165=IEA, GO:0005737=IDA, GO:0005543=IEA, GO:0005856=IEA, GO:0005925=IEA, GO:0005096=IEA} angiogenesis, cell differentiation, regulation of small GTPase mediated signal transduction, signal transduction, small GTPase mediated signal transduction cell projection, cytoplasm, cytoskeleton, cytosol, focal adhesion, intracellular, plasma membrane GTPase activator activity, phospholipid binding Human ARHGAP25 Reactome UniProtKB {GO:0005622=GO_REF:0000002, GO:0051056=Reactome:REACT_11051, GO:0007165=GO_REF:0000002, GO:0005543=GO_REF:0000002, GO:0007264=Reactome:REACT_11044, GO:0005829=Reactome:REACT_9982, GO:0005096=GO_REF:0000037} P42331 Rho GTPase-activating protein 25 protein 20130301 {GO:0005622=IEA, GO:0051056=TAS, GO:0007165=IEA, GO:0005543=IEA, GO:0007264=TAS, GO:0005829=TAS, GO:0005096=IEA} regulation of small GTPase mediated signal transduction, signal transduction, small GTPase mediated signal transduction cytosol, intracellular GTPase activator activity, phospholipid binding Human ARHGAP26 GOC UniProtKB {GO:0005515=PMID:11432776, GO:0051056=Reactome:REACT_11051, GO:0017124=GO_REF:0000002, GO:0030036=PMID:11998687, GO:0007264=Reactome:REACT_11044, GO:0005575=GO_REF:0000015, GO:0005100=PMID:10908648, GO:0007399=PMID:9582072, GO:0005829=Reactome:REACT_9982, GO:0005622=GO_REF:0000002, GO:0007165=GO_REF:0000002, GO:0005543=GO_REF:0000002, GO:0032321=PMID:10908648, GO:0046847=GO_REF:0000002, GO:0005856=GO_REF:0000039, GO:0005925=GO_REF:0000039, GO:0008093=GO_REF:0000002} Q9UNA1 Rho GTPase-activating protein 26 protein 20130413 {GO:0005515=IPI, GO:0051056=TAS, GO:0017124=IEA, GO:0030036=NAS, GO:0007264=TAS, GO:0005575=ND, GO:0005100=NAS, GO:0007399=NAS, GO:0005829=TAS, GO:0005622=IEA, GO:0007165=IEA, GO:0005543=IEA, GO:0032321=NAS, GO:0046847=IEA, GO:0005856=IEA, GO:0005925=IEA, GO:0008093=IEA} actin cytoskeleton organization, filopodium assembly, nervous system development, positive regulation of Rho GTPase activity, regulation of small GTPase mediated signal transduction, signal transduction, small GTPase mediated signal transduction cellular_component, cytoskeleton, cytosol, focal adhesion, intracellular Rho GTPase activator activity, SH3 domain binding, cytoskeletal adaptor activity, phospholipid binding, protein binding Human ARHGAP27 GOC UniProtKB {GO:0005622=GO_REF:0000024, GO:0007165=GO_REF:0000002, GO:0017124=GO_REF:0000024, GO:0005737=GO_REF:0000039, GO:0005543=GO_REF:0000002, GO:0016020=GO_REF:0000039, GO:0043089=GO_REF:0000024, GO:0032855=GO_REF:0000024, GO:0030675=GO_REF:0000024, GO:0006898=GO_REF:0000024, GO:0005096=GO_REF:0000038} Q6ZUM4 Rho GTPase-activating protein 27 protein 20130413 {GO:0005622=ISS, GO:0007165=IEA, GO:0017124=ISS, GO:0005737=IEA, GO:0005543=IEA, GO:0016020=IEA, GO:0043089=ISS, GO:0032855=ISS, GO:0030675=ISS, GO:0006898=ISS, GO:0005096=IEA} positive regulation of Cdc42 GTPase activity, positive regulation of Rac GTPase activity, receptor-mediated endocytosis, signal transduction cytoplasm, intracellular, membrane GTPase activator activity, Rac GTPase activator activity, SH3 domain binding, phospholipid binding Human UniProtKB:Q6TLK4 ARHGAP28 HPA UniProtKB {GO:0005622=GO_REF:0000002, GO:0051056=Reactome:REACT_11051, GO:0007165=GO_REF:0000002, GO:0007264=Reactome:REACT_11044, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0005829=Reactome:REACT_9982, GO:0005096=GO_REF:0000037} Q9P2N2 Rho GTPase-activating protein 28 protein 20101115 {GO:0005622=IEA, GO:0051056=TAS, GO:0007165=IEA, GO:0007264=TAS, GO:0005730=IDA, GO:0005634=IDA, GO:0005829=TAS, GO:0005096=IEA} regulation of small GTPase mediated signal transduction, signal transduction, small GTPase mediated signal transduction cytosol, intracellular, nucleolus, nucleus GTPase activator activity NOT Human ARHGAP29 GOC UniProtKB {GO:0035556=GO_REF:0000002, GO:0005622=GO_REF:0000002, GO:0051056=Reactome:REACT_11051, GO:0032321=PMID:9305890, GO:0007264=Reactome:REACT_11044, GO:0007266=PMID:9305890, GO:0005100=PMID:9305890, GO:0046872=GO_REF:0000037, GO:0005829=Reactome:REACT_9982} Q52LW3 Rho GTPase-activating protein 29 protein 20130413 {GO:0035556=IEA, GO:0005622=IEA, GO:0051056=TAS, GO:0032321=TAS, GO:0007264=TAS, GO:0007266=TAS, GO:0005100=TAS, GO:0046872=IEA, GO:0005829=TAS} Rho protein signal transduction, intracellular signal transduction, positive regulation of Rho GTPase activity, regulation of small GTPase mediated signal transduction, small GTPase mediated signal transduction cytosol, intracellular Rho GTPase activator activity, metal ion binding Human ARHGAP30 Reactome UniProtKB {GO:0005622=GO_REF:0000002, GO:0051056=Reactome:REACT_11051, GO:0007165=GO_REF:0000002, GO:0007264=Reactome:REACT_11044, GO:0016023=GO_REF:0000039, GO:0005829=Reactome:REACT_9982, GO:0005096=GO_REF:0000037} Q7Z6I6 Rho GTPase-activating protein 30 protein 20130301 {GO:0005622=IEA, GO:0051056=TAS, GO:0007165=IEA, GO:0007264=TAS, GO:0016023=IEA, GO:0005829=TAS, GO:0005096=IEA} regulation of small GTPase mediated signal transduction, signal transduction, small GTPase mediated signal transduction cytoplasmic membrane-bounded vesicle, cytosol, intracellular GTPase activator activity Human ARHGAP31 Reactome UniProtKB {GO:0005622=GO_REF:0000002, GO:0051056=Reactome:REACT_11051, GO:0007165=GO_REF:0000002, GO:0017124=GO_REF:0000019, GO:0007264=Reactome:REACT_11044, GO:0005925=GO_REF:0000039, GO:0030027=GO_REF:0000039, GO:0005829=Reactome:REACT_9982, GO:0005096=GO_REF:0000019} Q2M1Z3 Rho GTPase-activating protein 31 protein 20130301 {GO:0005622=IEA, GO:0051056=TAS, GO:0007165=IEA, GO:0017124=IEA, GO:0007264=TAS, GO:0005925=IEA, GO:0030027=IEA, GO:0005829=TAS, GO:0005096=IEA} regulation of small GTPase mediated signal transduction, signal transduction, small GTPase mediated signal transduction cytosol, focal adhesion, intracellular, lamellipodium GTPase activator activity, SH3 domain binding Human ARHGAP32 InterPro UniProtKB {GO:0005515=PMID:12788081, GO:0051056=Reactome:REACT_11051, GO:0030054=GO_REF:0000037, GO:0005886=GO_REF:0000037, GO:0007264=Reactome:REACT_11044, GO:0014069=GO_REF:0000039, GO:0015629=GO_REF:0000019, GO:0005829=Reactome:REACT_9982, GO:0005622=GO_REF:0000002, GO:0007165=GO_REF:0000002, GO:0007154=GO_REF:0000002, GO:0000139=GO_REF:0000039, GO:0045211=GO_REF:0000037, GO:0005789=GO_REF:0000039, GO:0035091=GO_REF:0000002, GO:0005938=GO_REF:0000039, GO:0010008=GO_REF:0000039, GO:0005096=GO_REF:0000037} G3V174 Rho GTPase-activating protein, isoform CRA_b protein 20130413 {GO:0005515=IPI, GO:0051056=TAS, GO:0030054=IEA, GO:0005886=IEA, GO:0007264=TAS, GO:0014069=IEA, GO:0015629=IEA, GO:0005829=TAS, GO:0005622=IEA, GO:0007165=IEA, GO:0007154=IEA, GO:0000139=IEA, GO:0045211=IEA, GO:0005789=IEA, GO:0035091=IEA, GO:0005938=IEA, GO:0010008=IEA, GO:0005096=IEA} cell communication, regulation of small GTPase mediated signal transduction, signal transduction, small GTPase mediated signal transduction Golgi membrane, actin cytoskeleton, cell cortex, cell junction, cytosol, endoplasmic reticulum membrane, endosome membrane, intracellular, plasma membrane, postsynaptic density, postsynaptic membrane GTPase activator activity, phosphatidylinositol binding, protein binding Human InterPro:IPR001683 ARHGAP33 IntAct UniProtKB {GO:0005515=PMID:16777849, GO:0005622=GO_REF:0000002, GO:0007165=GO_REF:0000002, GO:0005737=GO_REF:0000019, GO:0005886=GO_REF:0000019, GO:0015031=GO_REF:0000037, GO:0035091=GO_REF:0000002, GO:0030675=GO_REF:0000019} O14559 Rho GTPase-activating protein 33 protein 20130415 {GO:0005515=IPI, GO:0005622=IEA, GO:0007165=IEA, GO:0005737=IEA, GO:0005886=IEA, GO:0015031=IEA, GO:0035091=IEA, GO:0030675=IEA} protein transport, signal transduction cytoplasm, intracellular, plasma membrane Rac GTPase activator activity, phosphatidylinositol binding, protein binding Human UniProtKB:P06241 ARHGAP35 GOC UniProtKB {GO:0051056=Reactome:REACT_11051, GO:0007264=Reactome:REACT_11044, GO:0008360=GO_REF:0000019, GO:0003714=PMID:1894621, GO:0001843=GO_REF:0000019, GO:0005634=PMID:1894621, GO:0005525=GO_REF:0000002, GO:0015629=GO_REF:0000019, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037, GO:0005100=Reactome:REACT_19242, GO:0005829=Reactome:REACT_19356, GO:0032321=Reactome:REACT_19242, GO:0007411=Reactome:REACT_18266, GO:0043010=GO_REF:0000019, GO:0030900=GO_REF:0000019, GO:0045892=PMID:1894621, GO:0043116=GO_REF:0000019} Q9NRY4 Rho GTPase-activating protein 35 protein 20130413 {GO:0051056=TAS, GO:0007264=TAS, GO:0008360=IEA, GO:0003714=TAS, GO:0001843=IEA, GO:0005634=IC, GO:0005525=IEA, GO:0015629=IEA, GO:0003677=IEA, GO:0006351=IEA, GO:0005100=TAS, GO:0005829=TAS, GO:0032321=TAS, GO:0007411=TAS, GO:0043010=IEA, GO:0030900=IEA, GO:0045892=IDA, GO:0043116=IEA} axon guidance, camera-type eye development, forebrain development, negative regulation of transcription, DNA-dependent, negative regulation of vascular permeability, neural tube closure, positive regulation of Rho GTPase activity, regulation of cell shape, regulation of small GTPase mediated signal transduction, small GTPase mediated signal transduction, transcription, DNA-dependent actin cytoskeleton, cytosol, nucleus DNA binding, GTP binding, Rho GTPase activator activity, transcription corepressor activity Human ARHGAP39 Reactome UniProtKB {GO:0051056=Reactome:REACT_11051, GO:0007411=Reactome:REACT_18266, GO:0007264=Reactome:REACT_11044, GO:0005634=GO_REF:0000039, GO:0005856=GO_REF:0000002, GO:0005829=Reactome:REACT_9982} Q9C0H5 Rho GTPase-activating protein 39 protein 20130301 {GO:0051056=TAS, GO:0007411=TAS, GO:0007264=TAS, GO:0005634=IEA, GO:0005856=IEA, GO:0005829=TAS} axon guidance, regulation of small GTPase mediated signal transduction, small GTPase mediated signal transduction cytoskeleton, cytosol, nucleus Human ARHGAP4 GOC UniProtKB {GO:0005515=PMID:16417406, GO:0051056=Reactome:REACT_11051, GO:0048011=Reactome:REACT_13776, GO:0007264=Reactome:REACT_11044, GO:0005730=GO_REF:0000052, GO:0006915=Reactome:REACT_13638, GO:0005634=GO_REF:0000052, GO:0007266=PMID:8570618, GO:0097190=Reactome:REACT_13720, GO:0005100=PMID:8570618, GO:0005829=Reactome:REACT_19216, GO:0005622=GO_REF:0000002, GO:0007165=GO_REF:0000002, GO:0005737=GO_REF:0000052, GO:0032321=PMID:8570618, GO:0005070=PMID:8570618, GO:0007010=PMID:8570618, GO:0005925=GO_REF:0000052} P98171 Rho GTPase-activating protein 4 protein 20130413 {GO:0005515=IPI, GO:0051056=TAS, GO:0048011=TAS, GO:0007264=TAS, GO:0005730=IDA, GO:0006915=TAS, GO:0005634=IDA, GO:0007266=TAS, GO:0097190=TAS, GO:0005100=TAS, GO:0005829=TAS, GO:0005622=IEA, GO:0007165=IEA, GO:0005737=IDA, GO:0032321=TAS, GO:0005070=TAS, GO:0007010=TAS, GO:0005925=IDA} Rho protein signal transduction, apoptotic process, apoptotic signaling pathway, cytoskeleton organization, neurotrophin TRK receptor signaling pathway, positive regulation of Rho GTPase activity, regulation of small GTPase mediated signal transduction, signal transduction, small GTPase mediated signal transduction cytoplasm, cytosol, focal adhesion, intracellular, nucleolus, nucleus Rho GTPase activator activity, SH3/SH2 adaptor activity, protein binding Human ARHGAP44 Reactome UniProtKB {GO:0005515=PMID:19273615, GO:0005622=GO_REF:0000002, GO:0051056=Reactome:REACT_11051, GO:0007165=GO_REF:0000002, GO:0005737=GO_REF:0000002, GO:0007264=Reactome:REACT_11044, GO:0005829=Reactome:REACT_9982, GO:0005096=GO_REF:0000037} Q17R89 Rho GTPase-activating protein 44 protein 20130301 {GO:0005515=IPI, GO:0005622=IEA, GO:0051056=TAS, GO:0007165=IEA, GO:0005737=IEA, GO:0007264=TAS, GO:0005829=TAS, GO:0005096=IEA} regulation of small GTPase mediated signal transduction, signal transduction, small GTPase mediated signal transduction cytoplasm, cytosol, intracellular GTPase activator activity, protein binding Human ARHGAP5 GOC UniProtKB {GO:0051056=Reactome:REACT_11051, GO:0008361=GO_REF:0000019, GO:0030335=GO_REF:0000019, GO:0007264=Reactome:REACT_11044, GO:0003924=PMID:8537347, GO:0002053=GO_REF:0000019, GO:0007266=PMID:8537347, GO:0005525=GO_REF:0000002, GO:0005100=PMID:8537347, GO:0005829=Reactome:REACT_9982, GO:0006184=PMID:8537347, GO:0005622=GO_REF:0000002, GO:0007165=GO_REF:0000002, GO:0005737=PMID:8537347, GO:0016020=GO_REF:0000039, GO:0032321=PMID:8537347, GO:0007155=PMID:8537347, GO:0042169=PMID:1689011} Q13017 Rho GTPase-activating protein 5 protein 20130413 {GO:0051056=TAS, GO:0008361=IEA, GO:0030335=IEA, GO:0007264=TAS, GO:0003924=TAS, GO:0002053=IEA, GO:0007266=TAS, GO:0005525=IEA, GO:0005100=TAS, GO:0005829=TAS, GO:0006184=TAS, GO:0005622=IEA, GO:0007165=IEA, GO:0005737=TAS, GO:0016020=IEA, GO:0032321=TAS, GO:0007155=TAS, GO:0042169=IPI} GTP catabolic process, Rho protein signal transduction, cell adhesion, positive regulation of Rho GTPase activity, positive regulation of cell migration, positive regulation of mesenchymal cell proliferation, regulation of cell size, regulation of small GTPase mediated signal transduction, signal transduction, small GTPase mediated signal transduction cytoplasm, cytosol, intracellular, membrane GTP binding, GTPase activity, Rho GTPase activator activity, SH2 domain binding Human ARHGAP6 BHF-UCL UniProtKB {GO:0051056=Reactome:REACT_11051, GO:0017124=GO_REF:0000037, GO:0007264=Reactome:REACT_11044, GO:0005884=PMID:10699171, GO:0007266=PMID:10699171, GO:0015629=PMID:10699171, GO:0043087=PMID:10699171, GO:0005100=PMID:10699171, GO:0051895=PMID:10699171, GO:0005829=Reactome:REACT_9982, GO:0051497=PMID:10699171, GO:0005622=GO_REF:0000002, GO:0007165=GO_REF:0000002, GO:0005737=PMID:10699171, GO:0048041=GO_REF:0000019, GO:0005070=PMID:8570618, GO:0030041=PMID:10699171} O43182 Rho GTPase-activating protein 6 protein 20081126 {GO:0051056=TAS, GO:0017124=IEA, GO:0007264=TAS, GO:0005884=NAS, GO:0007266=NAS, GO:0015629=ISS, GO:0043087=ISS, GO:0005100=ISS, GO:0051895=IMP, GO:0005829=TAS, GO:0051497=IMP, GO:0005622=IEA, GO:0007165=IEA, GO:0005737=IMP, GO:0048041=IEA, GO:0005070=TAS, GO:0030041=NAS} Rho protein signal transduction, actin filament polymerization, focal adhesion assembly, negative regulation of focal adhesion assembly, negative regulation of stress fiber assembly, regulation of GTPase activity, regulation of small GTPase mediated signal transduction, signal transduction, small GTPase mediated signal transduction actin cytoskeleton, actin filament, cytoplasm, cytosol, intracellular Rho GTPase activator activity, SH3 domain binding, SH3/SH2 adaptor activity Human ARHGAP8 GOC UniProtKB {GO:0005515=PMID:20179103, GO:0005622=GO_REF:0000002, GO:0051056=Reactome:REACT_11051, GO:0007165=GO_REF:0000002, GO:0032321=PMID:20179103, GO:0007264=Reactome:REACT_11044, GO:0070374=PMID:20179103, GO:0005100=PMID:20179103, GO:0005829=Reactome:REACT_9982} P85298 Rho GTPase-activating protein 8 protein 20130413 {GO:0005515=IPI, GO:0005622=IEA, GO:0051056=TAS, GO:0007165=IEA, GO:0032321=IDA, GO:0007264=TAS, GO:0070374=IDA, GO:0005100=IDA, GO:0005829=TAS} positive regulation of ERK1 and ERK2 cascade, positive regulation of Rho GTPase activity, regulation of small GTPase mediated signal transduction, signal transduction, small GTPase mediated signal transduction cytosol, intracellular Rho GTPase activator activity, protein binding Human ARHGAP9 GOC UniProtKB {GO:0043547=PMID:11396949, GO:0005622=GO_REF:0000002, GO:0051056=Reactome:REACT_11051, GO:0007165=GO_REF:0000002, GO:0005543=GO_REF:0000002, GO:0007264=Reactome:REACT_11044, GO:0005829=Reactome:REACT_9982, GO:0005096=PMID:11396949} Q9BRR9 Rho GTPase-activating protein 9 protein 20130413 {GO:0043547=IDA, GO:0005622=IEA, GO:0051056=TAS, GO:0007165=IEA, GO:0005543=IEA, GO:0007264=TAS, GO:0005829=TAS, GO:0005096=IDA} positive regulation of GTPase activity, regulation of small GTPase mediated signal transduction, signal transduction, small GTPase mediated signal transduction cytosol, intracellular GTPase activator activity, phospholipid binding Human ARHGDIA IntAct UniProtKB {GO:0005515=PMID:20711218, GO:0001772=GO_REF:0000019, GO:0051056=Reactome:REACT_11051, GO:0043066=PMID:16130169, GO:0048011=Reactome:REACT_13776, GO:0007264=Reactome:REACT_11044, GO:0006928=PMID:16130169, GO:0007266=GO_REF:0000019, GO:0005829=Reactome:REACT_13771, GO:0032880=GO_REF:0000019, GO:0005737=GO_REF:0000002, GO:0007162=PMID:8262133, GO:0050771=Reactome:REACT_13815, GO:0050772=Reactome:REACT_13779, GO:0005856=PMID:16130169, GO:0050770=Reactome:REACT_13620, GO:0005094=GO_REF:0000019, GO:0005096=GO_REF:0000037} P52565 Rho GDP-dissociation inhibitor 1 protein 20130415 {GO:0005515=IPI, GO:0001772=IEA, GO:0051056=TAS, GO:0043066=TAS, GO:0048011=TAS, GO:0007264=TAS, GO:0006928=TAS, GO:0007266=IEA, GO:0005829=TAS, GO:0032880=IEA, GO:0005737=IEA, GO:0007162=TAS, GO:0050771=TAS, GO:0050772=TAS, GO:0005856=TAS, GO:0050770=TAS, GO:0005094=IEA, GO:0005096=IEA} Rho protein signal transduction, cellular component movement, negative regulation of apoptotic process, negative regulation of axonogenesis, negative regulation of cell adhesion, neurotrophin TRK receptor signaling pathway, positive regulation of axonogenesis, regulation of axonogenesis, regulation of protein localization, regulation of small GTPase mediated signal transduction, small GTPase mediated signal transduction cytoplasm, cytoskeleton, cytosol, immunological synapse GTPase activator activity, Rho GDP-dissociation inhibitor activity, protein binding Human UniProtKB:P61586 ARHGDIB Reactome UniProtKB {GO:0051056=Reactome:REACT_11051, GO:0030036=PMID:8262133, GO:0007264=Reactome:REACT_11044, GO:0006928=PMID:16130169, GO:0007275=PMID:8434008, GO:0007266=PMID:8356058, GO:0005829=Reactome:REACT_10055, GO:0005737=PMID:16130169, GO:0006955=PMID:8356058, GO:0007162=PMID:9113980, GO:0016023=PMID:9113980, GO:0005856=PMID:16130169, GO:0005094=GO_REF:0000002, GO:0005096=GO_REF:0000037} P52566 Rho GDP-dissociation inhibitor 2 protein 20130301 {GO:0051056=TAS, GO:0030036=TAS, GO:0007264=TAS, GO:0006928=TAS, GO:0007275=TAS, GO:0007266=TAS, GO:0005829=TAS, GO:0005737=TAS, GO:0006955=TAS, GO:0007162=TAS, GO:0016023=TAS, GO:0005856=TAS, GO:0005094=IEA, GO:0005096=IEA} Rho protein signal transduction, actin cytoskeleton organization, cellular component movement, immune response, multicellular organismal development, negative regulation of cell adhesion, regulation of small GTPase mediated signal transduction, small GTPase mediated signal transduction cytoplasm, cytoplasmic membrane-bounded vesicle, cytoskeleton, cytosol GTPase activator activity, Rho GDP-dissociation inhibitor activity Human ARHGDIG Reactome UniProtKB {GO:0032880=GO_REF:0000019, GO:0051056=Reactome:REACT_11051, GO:0007162=PMID:9113980, GO:0005737=GO_REF:0000002, GO:0016020=GO_REF:0000019, GO:0007264=Reactome:REACT_11044, GO:0016023=PMID:9113980, GO:0007266=PMID:9113980, GO:0005094=GO_REF:0000002, GO:0005829=Reactome:REACT_10055, GO:0005096=GO_REF:0000037} Q99819 Rho GDP-dissociation inhibitor 3 protein 20130301 {GO:0032880=IEA, GO:0051056=TAS, GO:0007162=TAS, GO:0005737=IEA, GO:0016020=IEA, GO:0007264=TAS, GO:0016023=TAS, GO:0007266=TAS, GO:0005094=IEA, GO:0005829=TAS, GO:0005096=IEA} Rho protein signal transduction, negative regulation of cell adhesion, regulation of protein localization, regulation of small GTPase mediated signal transduction, small GTPase mediated signal transduction cytoplasm, cytoplasmic membrane-bounded vesicle, cytosol, membrane GTPase activator activity, Rho GDP-dissociation inhibitor activity Human ARHGEF1 HPA UniProtKB {GO:0005515=PMID:12681510, GO:0048011=Reactome:REACT_13776, GO:0005886=Reactome:REACT_56, GO:0035023=GO_REF:0000002, GO:0008283=PMID:8810315, GO:0038032=GO_REF:0000002, GO:0007266=PMID:10747909, GO:0005829=Reactome:REACT_56, GO:0005622=GO_REF:0000002, GO:0005737=GO_REF:0000052, GO:0005543=GO_REF:0000002, GO:0050771=Reactome:REACT_13815, GO:0005089=GO_REF:0000002, GO:0050770=Reactome:REACT_13620, GO:0005096=GO_REF:0000037} Q92888 Rho guanine nucleotide exchange factor 1 protein 20081203 {GO:0005515=IPI, GO:0048011=TAS, GO:0005886=TAS, GO:0035023=IEA, GO:0008283=TAS, GO:0038032=IEA, GO:0007266=TAS, GO:0005829=TAS, GO:0005622=IEA, GO:0005737=IDA, GO:0005543=IEA, GO:0050771=TAS, GO:0005089=IEA, GO:0050770=TAS, GO:0005096=IEA} Rho protein signal transduction, cell proliferation, negative regulation of axonogenesis, neurotrophin TRK receptor signaling pathway, regulation of Rho protein signal transduction, regulation of axonogenesis, termination of G-protein coupled receptor signaling pathway cytoplasm, cytosol, intracellular, plasma membrane GTPase activator activity, Rho guanyl-nucleotide exchange factor activity, phospholipid binding, protein binding Human ARHGEF10 BHF-UCL UniProtKB {GO:0005622=GO_REF:0000002, GO:0051298=PMID:19635168, GO:0005813=PMID:19635168, GO:0035023=GO_REF:0000002, GO:0022011=PMID:14508709, GO:0051496=PMID:16896804, GO:0033126=PMID:19635168, GO:0019894=PMID:19635168, GO:0090307=PMID:19635168, GO:0005089=PMID:20042462, GO:0005829=PMID:16896804} O15013 Rho guanine nucleotide exchange factor 10 protein 20110614 {GO:0005622=IEA, GO:0051298=IMP, GO:0005813=IDA, GO:0035023=IEA, GO:0022011=IMP, GO:0051496=IMP, GO:0033126=IDA, GO:0019894=IPI, GO:0090307=IMP, GO:0005089=IDA, GO:0005829=NAS} centrosome duplication, myelination in peripheral nervous system, positive regulation of GTP catabolic process, positive regulation of stress fiber assembly, regulation of Rho protein signal transduction, spindle assembly involved in mitosis centrosome, cytosol, intracellular Rho guanyl-nucleotide exchange factor activity, kinesin binding Human ARHGEF10L UniProtKB UniProtKB {GO:0005622=GO_REF:0000002, GO:0005737=GO_REF:0000039, GO:0032933=PMID:16112081, GO:0032321=PMID:16112081, GO:0035023=GO_REF:0000002, GO:0051496=PMID:16112081, GO:0005089=GO_REF:0000002, GO:0005100=PMID:16112081, GO:0005829=PMID:16112081} Q9HCE6 Rho guanine nucleotide exchange factor 10-like protein protein 20130413 {GO:0005622=IEA, GO:0005737=IEA, GO:0032933=IDA, GO:0032321=IDA, GO:0035023=IEA, GO:0051496=IDA, GO:0005089=IEA, GO:0005100=IDA, GO:0005829=IDA} SREBP signaling pathway, positive regulation of Rho GTPase activity, positive regulation of stress fiber assembly, regulation of Rho protein signal transduction cytoplasm, cytosol, intracellular Rho GTPase activator activity, Rho guanyl-nucleotide exchange factor activity Human UniProtKB-SubCell:SL-0086 ARHGEF11 IntAct UniProtKB {GO:0005515=PMID:21988832, GO:0030036=PMID:10026210, GO:0035023=GO_REF:0000002, GO:0007264=Reactome:REACT_11044, GO:0006941=PMID:10026210, GO:0038032=GO_REF:0000002, GO:0006928=PMID:10026210, GO:0030010=PMID:10026210, GO:0007266=PMID:10026210, GO:0001558=PMID:10026210, GO:0005829=Reactome:REACT_19216, GO:0005622=PMID:10026210, GO:0000910=PMID:10026210, GO:0005737=PMID:15755723, GO:0005543=GO_REF:0000002, GO:0007411=Reactome:REACT_18266, GO:0005089=PMID:10026210, GO:0051056=Reactome:REACT_11051, GO:0048011=Reactome:REACT_13776, GO:0001664=PMID:15755723, GO:0006915=Reactome:REACT_13638, GO:0097190=Reactome:REACT_13720, GO:0016020=GO_REF:0000039, GO:0007186=PMID:15755723, GO:0045893=PMID:10026210, GO:0005096=GO_REF:0000037} O15085 Rho guanine nucleotide exchange factor 11 protein 20130415 {GO:0005515=IPI, GO:0030036=NAS, GO:0035023=IEA, GO:0007264=TAS, GO:0006941=NAS, GO:0038032=IEA, GO:0006928=NAS, GO:0030010=NAS, GO:0007266=IDA, GO:0001558=NAS, GO:0005829=TAS, GO:0005622=IC, GO:0000910=NAS, GO:0005737=IDA, GO:0005543=IEA, GO:0007411=TAS, GO:0005089=TAS, GO:0051056=TAS, GO:0048011=TAS, GO:0001664=IDA, GO:0006915=TAS, GO:0097190=TAS, GO:0016020=IEA, GO:0007186=IDA, GO:0045893=IDA, GO:0005096=IEA} G-protein coupled receptor signaling pathway, Rho protein signal transduction, actin cytoskeleton organization, apoptotic process, apoptotic signaling pathway, axon guidance, cellular component movement, cytokinesis, establishment of cell polarity, neurotrophin TRK receptor signaling pathway, positive regulation of transcription, DNA-dependent, regulation of Rho protein signal transduction, regulation of cell growth, regulation of small GTPase mediated signal transduction, small GTPase mediated signal transduction, striated muscle contraction, termination of G-protein coupled receptor signaling pathway cytoplasm, cytosol, intracellular, membrane G-protein coupled receptor binding, GTPase activator activity, Rho guanyl-nucleotide exchange factor activity, phospholipid binding, protein binding Human UniProtKB:P61586 ARHGEF12 Reactome UniProtKB {GO:0005515=PMID:20844236, GO:0051056=Reactome:REACT_11051, GO:0048011=Reactome:REACT_13776, GO:0001664=PMID:15755723, GO:0007264=Reactome:REACT_11044, GO:0035023=GO_REF:0000002, GO:0038032=GO_REF:0000002, GO:0006915=Reactome:REACT_13638, GO:0097190=Reactome:REACT_13720, GO:0005829=Reactome:REACT_19360, GO:0035556=GO_REF:0000002, GO:0005737=PMID:15755723, GO:0005543=GO_REF:0000002, GO:0016020=GO_REF:0000039, GO:0007186=PMID:15755723, GO:0007411=Reactome:REACT_18266, GO:0005089=GO_REF:0000002, GO:0005096=GO_REF:0000037} Q9NZN5 Rho guanine nucleotide exchange factor 12 protein 20130301 {GO:0005515=IPI, GO:0051056=TAS, GO:0048011=TAS, GO:0001664=IDA, GO:0007264=TAS, GO:0035023=IEA, GO:0038032=IEA, GO:0006915=TAS, GO:0097190=TAS, GO:0005829=TAS, GO:0035556=IEA, GO:0005737=IDA, GO:0005543=IEA, GO:0016020=IEA, GO:0007186=IDA, GO:0007411=TAS, GO:0005089=IEA, GO:0005096=IEA} G-protein coupled receptor signaling pathway, apoptotic process, apoptotic signaling pathway, axon guidance, intracellular signal transduction, neurotrophin TRK receptor signaling pathway, regulation of Rho protein signal transduction, regulation of small GTPase mediated signal transduction, small GTPase mediated signal transduction, termination of G-protein coupled receptor signaling pathway cytoplasm, cytosol, membrane G-protein coupled receptor binding, GTPase activator activity, Rho guanyl-nucleotide exchange factor activity, phospholipid binding, protein binding Human ARHGEF15 UniProtKB UniProtKB {GO:0005515=PMID:12775584, GO:0005622=GO_REF:0000002, GO:0050790=PMID:12775584, GO:0035023=GO_REF:0000002, GO:2000297=GO_REF:0000024, GO:0005089=PMID:12775584, GO:0030425=GO_REF:0000024, GO:0005096=GO_REF:0000037} O94989 Rho guanine nucleotide exchange factor 15 protein 20110923 {GO:0005515=IPI, GO:0005622=IEA, GO:0050790=IDA, GO:0035023=IEA, GO:2000297=ISS, GO:0005089=IDA, GO:0030425=ISS, GO:0005096=IEA} negative regulation of synapse maturation, regulation of Rho protein signal transduction, regulation of catalytic activity dendrite, intracellular GTPase activator activity, Rho guanyl-nucleotide exchange factor activity, protein binding Human ARHGEF16 BHF-UCL UniProtKB {GO:0005515=PMID:20679435, GO:0051056=Reactome:REACT_11051, GO:0030971=PMID:20679435, GO:0048011=Reactome:REACT_13776, GO:0035023=GO_REF:0000002, GO:0007264=Reactome:REACT_11044, GO:0006915=Reactome:REACT_13638, GO:0030165=PMID:21139582, GO:0032863=PMID:20679435, GO:0032864=PMID:21139582, GO:0097190=Reactome:REACT_13720, GO:0005829=Reactome:REACT_19216, GO:0005622=GO_REF:0000002, GO:0005543=GO_REF:0000002, GO:0060326=PMID:20679435, GO:0017048=PMID:20679435, GO:0005089=PMID:20679435, GO:0090004=PMID:20679435} Q5VV41 Rho guanine nucleotide exchange factor 16 protein 20101230 {GO:0005515=IPI, GO:0051056=TAS, GO:0030971=IPI, GO:0048011=TAS, GO:0035023=IEA, GO:0007264=TAS, GO:0006915=TAS, GO:0030165=IPI, GO:0032863=IMP, GO:0032864=IDA, GO:0097190=TAS, GO:0005829=TAS, GO:0005622=IEA, GO:0005543=IEA, GO:0060326=IMP, GO:0017048=IPI, GO:0005089=IDA, GO:0090004=IMP} activation of Cdc42 GTPase activity, activation of Rac GTPase activity, apoptotic process, apoptotic signaling pathway, cell chemotaxis, neurotrophin TRK receptor signaling pathway, positive regulation of establishment of protein localization to plasma membrane, regulation of Rho protein signal transduction, regulation of small GTPase mediated signal transduction, small GTPase mediated signal transduction cytosol, intracellular PDZ domain binding, Rho GTPase binding, Rho guanyl-nucleotide exchange factor activity, phospholipid binding, protein binding, receptor tyrosine kinase binding Human UniProtKB:O14907 ARHGEF17 Reactome UniProtKB {GO:0005085=PMID:12071859, GO:0005622=GO_REF:0000002, GO:0051056=Reactome:REACT_11051, GO:0048011=Reactome:REACT_13776, GO:0030036=PMID:12071859, GO:0007264=Reactome:REACT_11044, GO:0035023=GO_REF:0000002, GO:0006915=Reactome:REACT_13638, GO:0005089=GO_REF:0000002, GO:0097190=Reactome:REACT_13720, GO:0005829=Reactome:REACT_19216} Q96PE2 Rho guanine nucleotide exchange factor 17 protein 20130301 {GO:0005085=IDA, GO:0005622=IEA, GO:0051056=TAS, GO:0048011=TAS, GO:0030036=IDA, GO:0007264=TAS, GO:0035023=IEA, GO:0006915=TAS, GO:0005089=IEA, GO:0097190=TAS, GO:0005829=TAS} actin cytoskeleton organization, apoptotic process, apoptotic signaling pathway, neurotrophin TRK receptor signaling pathway, regulation of Rho protein signal transduction, regulation of small GTPase mediated signal transduction, small GTPase mediated signal transduction cytosol, intracellular Rho guanyl-nucleotide exchange factor activity, guanyl-nucleotide exchange factor activity Human ARHGEF18 HPA UniProtKB {GO:0051056=Reactome:REACT_11051, GO:0048011=Reactome:REACT_13776, GO:0030036=PMID:14512443, GO:0030054=Reactome:REACT_121319, GO:0005886=GO_REF:0000052, GO:0035023=GO_REF:0000002, GO:0007264=Reactome:REACT_11044, GO:0008360=PMID:14512443, GO:0045177=PMID:22006950, GO:0006915=Reactome:REACT_13638, GO:0097190=Reactome:REACT_13720, GO:0005829=Reactome:REACT_19216, GO:0005622=GO_REF:0000002, GO:0005085=PMID:14512443, GO:0005737=GO_REF:0000052, GO:0005543=GO_REF:0000002, GO:0007179=Reactome:REACT_120726, GO:0005089=GO_REF:0000002} Q6ZSZ5 Rho guanine nucleotide exchange factor 18 protein 20111111 {GO:0051056=TAS, GO:0048011=TAS, GO:0030036=IDA, GO:0030054=TAS, GO:0005886=IDA, GO:0035023=IEA, GO:0007264=TAS, GO:0008360=IDA, GO:0045177=IDA, GO:0006915=TAS, GO:0097190=TAS, GO:0005829=TAS, GO:0005622=IEA, GO:0005085=IDA, GO:0005737=IDA, GO:0005543=IEA, GO:0007179=TAS, GO:0005089=IEA} actin cytoskeleton organization, apoptotic process, apoptotic signaling pathway, neurotrophin TRK receptor signaling pathway, regulation of Rho protein signal transduction, regulation of cell shape, regulation of small GTPase mediated signal transduction, small GTPase mediated signal transduction, transforming growth factor beta receptor signaling pathway apical part of cell, cell junction, cytoplasm, cytosol, intracellular, plasma membrane Rho guanyl-nucleotide exchange factor activity, guanyl-nucleotide exchange factor activity, phospholipid binding Human ARHGEF19 MGI UniProtKB {GO:0005622=GO_REF:0000002, GO:0005543=GO_REF:0000002, GO:0032321=GO_REF:0000019, GO:0035023=GO_REF:0000002, GO:0032956=PMID:20643356, GO:0042060=GO_REF:0000019, GO:0005089=GO_REF:0000002, GO:0005096=GO_REF:0000037} Q8IW93 Rho guanine nucleotide exchange factor 19 protein 20101206 {GO:0005622=IEA, GO:0005543=IEA, GO:0032321=IEA, GO:0035023=IEA, GO:0032956=IGI, GO:0042060=IEA, GO:0005089=IEA, GO:0005096=IEA} positive regulation of Rho GTPase activity, regulation of Rho protein signal transduction, regulation of actin cytoskeleton organization, wound healing intracellular GTPase activator activity, Rho guanyl-nucleotide exchange factor activity, phospholipid binding Human UniProtKB:Q8TE85 ARHGEF2 BHF-UCL UniProtKB {GO:0005515=PMID:19043560, GO:0008017=PMID:9857026, GO:0007264=Reactome:REACT_11044, GO:0035023=PMID:11912491, GO:0000132=GO_REF:0000019, GO:0006886=PMID:9857026, GO:0046872=GO_REF:0000038, GO:0005829=Reactome:REACT_19216, GO:0035556=GO_REF:0000002, GO:0005622=GO_REF:0000002, GO:0051092=PMID:19043560, GO:0005543=GO_REF:0000002, GO:0050768=GO_REF:0000019, GO:0043198=GO_REF:0000019, GO:0042127=PMID:9857026, GO:0071356=GO_REF:0000024, GO:0043025=GO_REF:0000019, GO:0060547=GO_REF:0000024, GO:0007015=PMID:9857026, GO:0005089=PMID:9857026, GO:0030676=PMID:9857026, GO:0071474=GO_REF:0000024, GO:0051056=Reactome:REACT_11051, GO:0043066=GO_REF:0000024, GO:0048011=Reactome:REACT_13776, GO:0005794=GO_REF:0000039, GO:0005874=PMID:9857026, GO:0005819=GO_REF:0000039, GO:0006915=Reactome:REACT_13638, GO:0032587=PMID:19043560, GO:0097190=Reactome:REACT_13720, GO:0048365=PMID:9857026, GO:0000902=PMID:11912491, GO:0007067=GO_REF:0000037, GO:0007026=PMID:11912491, GO:0008270=PMID:11912491, GO:0017048=PMID:9857026, GO:0005923=GO_REF:0000039, GO:0008134=GO_REF:0000024, GO:0051301=GO_REF:0000037} Q92974 Rho guanine nucleotide exchange factor 2 protein 20130114 {GO:0005515=IPI, GO:0008017=IDA, GO:0007264=TAS, GO:0035023=NAS, GO:0000132=IEA, GO:0006886=NAS, GO:0046872=IEA, GO:0005829=TAS, GO:0035556=IEA, GO:0005622=IEA, GO:0051092=IDA, GO:0005543=IEA, GO:0050768=IEA, GO:0043198=IEA, GO:0042127=TAS, GO:0071356=ISS, GO:0043025=IEA, GO:0060547=ISS, GO:0007015=IMP, GO:0005089=IDA, GO:0030676=IDA, GO:0071474=ISS, GO:0051056=TAS, GO:0043066=ISS, GO:0048011=TAS, GO:0005794=IEA, GO:0005874=IDA, GO:0005819=IEA, GO:0006915=TAS, GO:0032587=IDA, GO:0097190=TAS, GO:0048365=IDA, GO:0000902=IMP, GO:0007067=IEA, GO:0007026=IMP, GO:0008270=NAS, GO:0017048=IDA, GO:0005923=IEA, GO:0008134=ISS, GO:0051301=IEA} actin filament organization, apoptotic process, apoptotic signaling pathway, cell division, cell morphogenesis, cellular hyperosmotic response, cellular response to tumor necrosis factor, establishment of mitotic spindle orientation, intracellular protein transport, intracellular signal transduction, mitosis, negative regulation of apoptotic process, negative regulation of microtubule depolymerization, negative regulation of necrotic cell death, negative regulation of neurogenesis, neurotrophin TRK receptor signaling pathway, positive regulation of NF-kappaB transcription factor activity, regulation of Rho protein signal transduction, regulation of cell proliferation, regulation of small GTPase mediated signal transduction, small GTPase mediated signal transduction Golgi apparatus, cytosol, dendritic shaft, intracellular, microtubule, neuronal cell body, ruffle membrane, spindle, tight junction Rac GTPase binding, Rac guanyl-nucleotide exchange factor activity, Rho GTPase binding, Rho guanyl-nucleotide exchange factor activity, metal ion binding, microtubule binding, phospholipid binding, protein binding, transcription factor binding, zinc ion binding Human UniProtKB:Q865S3 ARHGEF25 Reactome UniProtKB {GO:0005622=GO_REF:0000002, GO:0005543=GO_REF:0000002, GO:0005886=GO_REF:0000024, GO:0035023=GO_REF:0000002, GO:0030016=GO_REF:0000024, GO:0005089=GO_REF:0000002, GO:0030017=GO_REF:0000039, GO:0005829=Reactome:REACT_19301} Q86VW2 Rho guanine nucleotide exchange factor 25 protein 20090911 {GO:0005622=IEA, GO:0005543=IEA, GO:0005886=ISS, GO:0035023=IEA, GO:0030016=ISS, GO:0005089=IEA, GO:0030017=IEA, GO:0005829=TAS} regulation of Rho protein signal transduction cytosol, intracellular, myofibril, plasma membrane, sarcomere Rho guanyl-nucleotide exchange factor activity, phospholipid binding Human ARHGEF3 LIFEdb UniProtKB {GO:0035556=GO_REF:0000002, GO:0005622=GO_REF:0000054, GO:0051056=Reactome:REACT_11051, GO:0048011=Reactome:REACT_13776, GO:0005543=GO_REF:0000002, GO:0007264=Reactome:REACT_11044, GO:0035023=GO_REF:0000002, GO:0006915=Reactome:REACT_13638, GO:0007266=PMID:10873612, GO:0005089=GO_REF:0000002, GO:0097190=Reactome:REACT_13720, GO:0005829=Reactome:REACT_19216} Q9NR81 Rho guanine nucleotide exchange factor 3 protein 20100607 {GO:0035556=IEA, GO:0005622=IDA, GO:0051056=TAS, GO:0048011=TAS, GO:0005543=IEA, GO:0007264=TAS, GO:0035023=IEA, GO:0006915=TAS, GO:0007266=TAS, GO:0005089=IEA, GO:0097190=TAS, GO:0005829=TAS} Rho protein signal transduction, apoptotic process, apoptotic signaling pathway, intracellular signal transduction, neurotrophin TRK receptor signaling pathway, regulation of Rho protein signal transduction, regulation of small GTPase mediated signal transduction, small GTPase mediated signal transduction cytosol, intracellular Rho guanyl-nucleotide exchange factor activity, phospholipid binding Human ARHGEF35 null null {} null null null null {} null null null ARHGEF4 Reactome UniProtKB {GO:0005515=PMID:17588722, GO:0051056=Reactome:REACT_11051, GO:0048011=Reactome:REACT_13776, GO:0007264=Reactome:REACT_11044, GO:0035023=GO_REF:0000002, GO:0019904=PMID:10947987, GO:0030032=PMID:17599059, GO:0006915=Reactome:REACT_13638, GO:0032587=GO_REF:0000039, GO:0097190=Reactome:REACT_13720, GO:0005829=Reactome:REACT_19216, GO:0035556=GO_REF:0000029, GO:0005085=PMID:17599059, GO:0005622=GO_REF:0000002, GO:0005543=GO_REF:0000002, GO:0046847=PMID:17599059, GO:0005089=GO_REF:0000029, GO:0030676=PMID:17599059} Q9NR80 Rho guanine nucleotide exchange factor 4 protein 20130301 {GO:0005515=IPI, GO:0051056=TAS, GO:0048011=TAS, GO:0007264=TAS, GO:0035023=IEA, GO:0019904=IPI, GO:0030032=IMP, GO:0006915=TAS, GO:0032587=IEA, GO:0097190=TAS, GO:0005829=TAS, GO:0035556=NAS, GO:0005085=IMP, GO:0005622=IEA, GO:0005543=IEA, GO:0046847=IMP, GO:0005089=NAS, GO:0030676=IMP} apoptotic process, apoptotic signaling pathway, filopodium assembly, intracellular signal transduction, lamellipodium assembly, neurotrophin TRK receptor signaling pathway, regulation of Rho protein signal transduction, regulation of small GTPase mediated signal transduction, small GTPase mediated signal transduction cytosol, intracellular, ruffle membrane Rac guanyl-nucleotide exchange factor activity, Rho guanyl-nucleotide exchange factor activity, guanyl-nucleotide exchange factor activity, phospholipid binding, protein binding, protein domain specific binding Human ARHGEF40 UniProtKB UniProtKB {GO:0005737=GO_REF:0000039, GO:0005543=GO_REF:0000002, GO:0035023=GO_REF:0000002, GO:0005089=GO_REF:0000002} Q8TER5 Rho guanine nucleotide exchange factor 40 protein 20130413 {GO:0005737=IEA, GO:0005543=IEA, GO:0035023=IEA, GO:0005089=IEA} regulation of Rho protein signal transduction cytoplasm Rho guanyl-nucleotide exchange factor activity, phospholipid binding Human UniProtKB-SubCell:SL-0086 ARHGEF5 HPA UniProtKB {GO:0035556=GO_REF:0000002, GO:0071803=GO_REF:0000019, GO:0005737=GO_REF:0000052, GO:0030036=GO_REF:0000019, GO:0005543=GO_REF:0000002, GO:0005886=GO_REF:0000052, GO:0032321=GO_REF:0000019, GO:0035023=GO_REF:0000002, GO:0002408=GO_REF:0000019, GO:0005525=PMID:8134109, GO:0032319=PMID:21525037, GO:0005089=GO_REF:0000002} Q12774 Rho guanine nucleotide exchange factor 5 protein 20101115 {GO:0035556=IEA, GO:0071803=IEA, GO:0005737=IDA, GO:0030036=IEA, GO:0005543=IEA, GO:0005886=IDA, GO:0032321=IEA, GO:0035023=IEA, GO:0002408=IEA, GO:0005525=TAS, GO:0032319=IDA, GO:0005089=IEA} actin cytoskeleton organization, intracellular signal transduction, myeloid dendritic cell chemotaxis, positive regulation of Rho GTPase activity, positive regulation of podosome assembly, regulation of Rho GTPase activity, regulation of Rho protein signal transduction cytoplasm, plasma membrane GTP binding, Rho guanyl-nucleotide exchange factor activity, phospholipid binding Human ARHGEF6 GOC UniProtKB {GO:0005515=PMID:21295525, GO:0051056=Reactome:REACT_11051, GO:0048011=Reactome:REACT_13776, GO:0035023=GO_REF:0000002, GO:0007264=Reactome:REACT_11044, GO:0034329=Reactome:REACT_20676, GO:0030032=GO_REF:0000024, GO:0007254=PMID:11564864, GO:0006915=Reactome:REACT_13638, GO:0097190=Reactome:REACT_13720, GO:0030027=GO_REF:0000024, GO:0005829=Reactome:REACT_20672, GO:0043547=PMID:9582122, GO:0005622=PMID:11017088, GO:0005737=GO_REF:0000052, GO:0005543=GO_REF:0000002, GO:0005089=PMID:11017088, GO:0005096=PMID:9582122} Q15052 Rho guanine nucleotide exchange factor 6 protein 20130413 {GO:0005515=IPI, GO:0051056=TAS, GO:0048011=TAS, GO:0035023=IEA, GO:0007264=TAS, GO:0034329=TAS, GO:0030032=ISS, GO:0007254=NAS, GO:0006915=TAS, GO:0097190=TAS, GO:0030027=ISS, GO:0005829=TAS, GO:0043547=NAS, GO:0005622=IC, GO:0005737=IDA, GO:0005543=IEA, GO:0005089=NAS, GO:0005096=NAS} JNK cascade, apoptotic process, apoptotic signaling pathway, cell junction assembly, lamellipodium assembly, neurotrophin TRK receptor signaling pathway, positive regulation of GTPase activity, regulation of Rho protein signal transduction, regulation of small GTPase mediated signal transduction, small GTPase mediated signal transduction cytoplasm, cytosol, intracellular, lamellipodium GTPase activator activity, Rho guanyl-nucleotide exchange factor activity, phospholipid binding, protein binding Human ARHGEF7 BHF-UCL UniProtKB {GO:0005515=PMID:21295525, GO:0043005=PMID:21048939, GO:0035023=GO_REF:0000002, GO:0007264=Reactome:REACT_11044, GO:0030032=GO_REF:0000024, GO:0005829=Reactome:REACT_19216, GO:0005085=PMID:21048939, GO:0035556=GO_REF:0000002, GO:0005622=GO_REF:0000002, GO:0005543=GO_REF:0000002, GO:0007173=Reactome:REACT_9417, GO:0043025=PMID:21048939, GO:0005089=GO_REF:0000002, GO:0005938=GO_REF:0000039, GO:0051056=Reactome:REACT_11051, GO:0048011=Reactome:REACT_13776, GO:0043065=PMID:19041750, GO:0019901=PMID:21048939, GO:0042059=Reactome:REACT_12484, GO:0006915=Reactome:REACT_13638, GO:0001726=GO_REF:0000039, GO:0097190=Reactome:REACT_13720, GO:0030027=GO_REF:0000024, GO:0007399=GO_REF:0000037, GO:0043547=PMID:21048939, GO:0043234=PMID:11864573, GO:0007165=PMID:9659915, GO:0005925=GO_REF:0000039} Q14155 Rho guanine nucleotide exchange factor 7 protein 20120315 {GO:0005515=IPI, GO:0043005=IDA, GO:0035023=IEA, GO:0007264=TAS, GO:0030032=ISS, GO:0005829=TAS, GO:0005085=IDA, GO:0035556=IEA, GO:0005622=IEA, GO:0005543=IEA, GO:0007173=TAS, GO:0043025=IDA, GO:0005089=IEA, GO:0005938=IEA, GO:0051056=TAS, GO:0048011=TAS, GO:0043065=IMP, GO:0019901=IPI, GO:0042059=TAS, GO:0006915=TAS, GO:0001726=IEA, GO:0097190=TAS, GO:0030027=ISS, GO:0007399=IEA, GO:0043547=IDA, GO:0043234=IDA, GO:0007165=TAS, GO:0005925=IEA} apoptotic process, apoptotic signaling pathway, epidermal growth factor receptor signaling pathway, intracellular signal transduction, lamellipodium assembly, negative regulation of epidermal growth factor receptor signaling pathway, nervous system development, neurotrophin TRK receptor signaling pathway, positive regulation of GTPase activity, positive regulation of apoptotic process, regulation of Rho protein signal transduction, regulation of small GTPase mediated signal transduction, signal transduction, small GTPase mediated signal transduction cell cortex, cytosol, focal adhesion, intracellular, lamellipodium, neuron projection, neuronal cell body, protein complex, ruffle Rho guanyl-nucleotide exchange factor activity, guanyl-nucleotide exchange factor activity, phospholipid binding, protein binding, protein kinase binding Human ARHGEF9 Reactome UniProtKB {GO:0051056=Reactome:REACT_11051, GO:0048011=Reactome:REACT_13776, GO:0035023=GO_REF:0000002, GO:0007264=Reactome:REACT_11044, GO:0006915=Reactome:REACT_13638, GO:0007268=Reactome:REACT_13685, GO:0055085=Reactome:REACT_15518, GO:0097190=Reactome:REACT_13720, GO:0005829=Reactome:REACT_25130, GO:0005622=GO_REF:0000002, GO:0005543=GO_REF:0000002, GO:0034220=Reactome:REACT_25387, GO:0005089=GO_REF:0000002} O43307 Rho guanine nucleotide exchange factor 9 protein 20130301 {GO:0051056=TAS, GO:0048011=TAS, GO:0035023=IEA, GO:0007264=TAS, GO:0006915=TAS, GO:0007268=TAS, GO:0055085=TAS, GO:0097190=TAS, GO:0005829=TAS, GO:0005622=IEA, GO:0005543=IEA, GO:0034220=TAS, GO:0005089=IEA} apoptotic process, apoptotic signaling pathway, ion transmembrane transport, neurotrophin TRK receptor signaling pathway, regulation of Rho protein signal transduction, regulation of small GTPase mediated signal transduction, small GTPase mediated signal transduction, synaptic transmission, transmembrane transport cytosol, intracellular Rho guanyl-nucleotide exchange factor activity, phospholipid binding Human ARID1A ENSEMBL UniProtKB {GO:0005515=PMID:17363140, GO:0016922=PMID:17363140, GO:0000790=PMID:17363140, GO:0071565=GO_REF:0000019, GO:0006357=PMID:8804307, GO:0003713=PMID:8804307, GO:0006325=GO_REF:0000019, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0006337=PMID:8895581, GO:0071564=GO_REF:0000019, GO:0003677=PMID:10757798, GO:0006351=GO_REF:0000037, GO:0007399=GO_REF:0000037, GO:0016514=GO_REF:0000019, GO:0042921=PMID:12200431, GO:0042766=PMID:12200431, GO:0006338=PMID:11726552, GO:0045893=PMID:12200431, GO:0048096=PMID:12200431, GO:0030521=PMID:12200431, GO:0030520=PMID:12200431} Q96SM7 AT-rich interactive domain-containing protein 1A protein 20130413 {GO:0005515=IPI, GO:0016922=IPI, GO:0000790=IDA, GO:0071565=IEA, GO:0006357=NAS, GO:0003713=NAS, GO:0006325=IEA, GO:0005730=IDA, GO:0005634=IDA, GO:0006337=IDA, GO:0071564=IEA, GO:0003677=NAS, GO:0006351=IEA, GO:0007399=IEA, GO:0016514=IEA, GO:0042921=IDA, GO:0042766=TAS, GO:0006338=IDA, GO:0045893=IDA, GO:0048096=TAS, GO:0030521=IDA, GO:0030520=IDA} androgen receptor signaling pathway, chromatin organization, chromatin remodeling, chromatin-mediated maintenance of transcription, glucocorticoid receptor signaling pathway, intracellular estrogen receptor signaling pathway, nervous system development, nucleosome disassembly, nucleosome mobilization, positive regulation of transcription, DNA-dependent, regulation of transcription from RNA polymerase II promoter, transcription, DNA-dependent SWI/SNF complex, nBAF complex, npBAF complex, nuclear chromatin, nucleolus, nucleus DNA binding, ligand-dependent nuclear receptor binding, protein binding, transcription coactivator activity Human Ensembl:ENSMUSP00000101517 ARID1B HPA UniProtKB {GO:0016514=PMID:11734557, GO:0003713=PMID:11734557, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0048096=PMID:11734557, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037, GO:0007399=GO_REF:0000037, GO:0043231=GO_REF:0000052} Q8NFD5 AT-rich interactive domain-containing protein 1B protein 20101115 {GO:0016514=IDA, GO:0003713=NAS, GO:0005730=IDA, GO:0005634=IDA, GO:0048096=NAS, GO:0003677=IEA, GO:0006351=IEA, GO:0007399=IEA, GO:0043231=IDA} chromatin-mediated maintenance of transcription, nervous system development, transcription, DNA-dependent SWI/SNF complex, intracellular membrane-bounded organelle, nucleolus, nucleus DNA binding, transcription coactivator activity Human ARID2 BHF-UCL UniProtKB {GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0006337=PMID:8895581, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037, GO:0016568=GO_REF:0000037} Q68CP9 AT-rich interactive domain-containing protein 2 protein 20110811 {GO:0006355=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0006337=IDA, GO:0003677=IEA, GO:0006351=IEA, GO:0016568=IEA} chromatin modification, nucleosome disassembly, regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus DNA binding, zinc ion binding Human ARID3A MGI UniProtKB {GO:0006355=GO_REF:0000029, GO:0005737=GO_REF:0000039, GO:0003700=GO_REF:0000029, GO:0045944=GO_REF:0000019, GO:0003682=GO_REF:0000019, GO:0045121=PMID:21955986, GO:0005634=GO_REF:0000029, GO:0003677=GO_REF:0000019, GO:0042803=GO_REF:0000019, GO:0006351=GO_REF:0000037} Q99856 AT-rich interactive domain-containing protein 3A protein 20120319 {GO:0006355=NAS, GO:0005737=IEA, GO:0003700=NAS, GO:0045944=IEA, GO:0003682=IEA, GO:0045121=IDA, GO:0005634=NAS, GO:0003677=IEA, GO:0042803=IEA, GO:0006351=IEA} positive regulation of transcription from RNA polymerase II promoter, regulation of transcription, DNA-dependent, transcription, DNA-dependent cytoplasm, membrane raft, nucleus DNA binding, chromatin binding, protein homodimerization activity, sequence-specific DNA binding transcription factor activity Human ARID3B UniProtKB UniProtKB {GO:0008150=GO_REF:0000015, GO:0006355=GO_REF:0000037, GO:0005634=PMID:10446990, GO:0003677=PMID:10446990, GO:0006351=GO_REF:0000037} Q8IVW6 AT-rich interactive domain-containing protein 3B protein 20070906 {GO:0008150=ND, GO:0006355=IEA, GO:0005634=NAS, GO:0003677=NAS, GO:0006351=IEA} biological_process, regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus DNA binding Human ARID4A GDB UniProtKB {GO:0003700=PMID:8414517, GO:0006366=PMID:8414517, GO:0017053=PMID:11283269, GO:0005634=PMID:11283269, GO:0045892=PMID:12724404, GO:0003677=GO_REF:0000002} P29374 AT-rich interactive domain-containing protein 4A protein 20050428 {GO:0003700=TAS, GO:0006366=TAS, GO:0017053=IDA, GO:0005634=IDA, GO:0045892=IDA, GO:0003677=IEA} negative regulation of transcription, DNA-dependent, transcription from RNA polymerase II promoter nucleus, transcriptional repressor complex DNA binding, sequence-specific DNA binding transcription factor activity Human ARID4B IntAct UniProtKB {GO:0005515=PMID:20195357, GO:0003674=GO_REF:0000015, GO:0008150=GO_REF:0000015, GO:0005737=GO_REF:0000039, GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0005575=GO_REF:0000015, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q4LE39 AT-rich interactive domain-containing protein 4B protein 20130415 {GO:0005515=IPI, GO:0003674=ND, GO:0008150=ND, GO:0005737=IEA, GO:0006355=IEA, GO:0005634=IEA, GO:0005575=ND, GO:0003677=IEA, GO:0006351=IEA} biological_process, regulation of transcription, DNA-dependent, transcription, DNA-dependent cellular_component, cytoplasm, nucleus DNA binding, molecular_function, protein binding Human UniProtKB:P14921 ARID5A HPA UniProtKB {GO:0005515=PMID:23275563, GO:0005667=GO_REF:0000019, GO:0002062=GO_REF:0000019, GO:0045944=GO_REF:0000019, GO:0003682=GO_REF:0000019, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0045892=PMID:15640446, GO:0035066=GO_REF:0000019, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037, GO:0008134=GO_REF:0000019} Q03989 AT-rich interactive domain-containing protein 5A protein 20100326 {GO:0005515=IPI, GO:0005667=IEA, GO:0002062=IEA, GO:0045944=IEA, GO:0003682=IEA, GO:0005730=IDA, GO:0005634=IDA, GO:0045892=TAS, GO:0035066=IEA, GO:0003677=IEA, GO:0006351=IEA, GO:0008134=IEA} chondrocyte differentiation, negative regulation of transcription, DNA-dependent, positive regulation of histone acetylation, positive regulation of transcription from RNA polymerase II promoter, transcription, DNA-dependent nucleolus, nucleus, transcription factor complex DNA binding, chromatin binding, protein binding, transcription factor binding Human ARID5B GDB UniProtKB {GO:0005515=PMID:21532585, GO:0030325=GO_REF:0000019, GO:0044212=PMID:21532585, GO:0048705=GO_REF:0000019, GO:0005634=GO_REF:0000039, GO:0009791=GO_REF:0000019, GO:0048644=GO_REF:0000019, GO:0010761=GO_REF:0000019, GO:0051091=PMID:21532585, GO:0035264=GO_REF:0000019, GO:0045444=GO_REF:0000019, GO:0060021=GO_REF:0000019, GO:0048468=GO_REF:0000019, GO:0001822=GO_REF:0000019, GO:0003713=PMID:21532585, GO:0003677=PMID:10329386, GO:0006351=GO_REF:0000037, GO:0001889=PMID:21532585, GO:0008585=GO_REF:0000019, GO:0060325=GO_REF:0000019, GO:0060613=GO_REF:0000019, GO:0048008=GO_REF:0000019, GO:0060612=GO_REF:0000024, GO:0045892=PMID:15640446, GO:0008584=GO_REF:0000019} Q14865 AT-rich interactive domain-containing protein 5B protein 20050428 {GO:0005515=IPI, GO:0030325=IEA, GO:0044212=IDA, GO:0048705=IEA, GO:0005634=IEA, GO:0009791=IEA, GO:0048644=IEA, GO:0010761=IEA, GO:0051091=IDA, GO:0035264=IEA, GO:0045444=IEA, GO:0060021=IEA, GO:0048468=IEA, GO:0001822=IEA, GO:0003713=IDA, GO:0003677=IDA, GO:0006351=IEA, GO:0001889=TAS, GO:0008585=IEA, GO:0060325=IEA, GO:0060613=IEA, GO:0048008=IEA, GO:0060612=ISS, GO:0045892=TAS, GO:0008584=IEA} adipose tissue development, adrenal gland development, cell development, face morphogenesis, fat cell differentiation, fat pad development, female gonad development, fibroblast migration, kidney development, liver development, male gonad development, multicellular organism growth, muscle organ morphogenesis, negative regulation of transcription, DNA-dependent, palate development, platelet-derived growth factor receptor signaling pathway, positive regulation of sequence-specific DNA binding transcription factor activity, post-embryonic development, skeletal system morphogenesis, transcription, DNA-dependent nucleus DNA binding, protein binding, transcription coactivator activity, transcription regulatory region DNA binding Human ARIH1 Reactome UniProtKB {GO:0005515=PMID:14623119, GO:0006511=PMID:10521492, GO:0005737=PMID:11278816, GO:0004842=PMID:21532592, GO:0016567=PMID:21532592, GO:0019787=PMID:10521492, GO:0019221=Reactome:REACT_25229, GO:0000151=PMID:10521492, GO:0008270=PMID:15236971, GO:0031625=PMID:21532592, GO:0005829=Reactome:REACT_116157} Q9Y4X5 E3 ubiquitin-protein ligase ARIH1 protein 20130301 {GO:0005515=IPI, GO:0006511=TAS, GO:0005737=IDA, GO:0004842=IDA, GO:0016567=IDA, GO:0019787=TAS, GO:0019221=TAS, GO:0000151=TAS, GO:0008270=IDA, GO:0031625=IPI, GO:0005829=TAS} cytokine-mediated signaling pathway, protein ubiquitination, ubiquitin-dependent protein catabolic process cytoplasm, cytosol, ubiquitin ligase complex protein binding, small conjugating protein ligase activity, ubiquitin protein ligase binding, ubiquitin-protein ligase activity, zinc ion binding Human ARIH2 IntAct UniProtKB {GO:0000209=PMID:19340006, GO:0005515=PMID:19549727, GO:0006511=GO_REF:0000019, GO:0004842=PMID:16118314, GO:0007275=PMID:10422847, GO:0005634=PMID:16118314, GO:0003676=GO_REF:0000002, GO:0048588=PMID:19340006, GO:0005737=PMID:19340006, GO:0070534=PMID:19340006, GO:0071425=PMID:16118314, GO:0042787=PMID:16118314, GO:0008270=GO_REF:0000002, GO:0070936=PMID:19340006} O95376 E3 ubiquitin-protein ligase ARIH2 protein 20130415 {GO:0000209=IDA, GO:0005515=IPI, GO:0006511=IEA, GO:0004842=IDA, GO:0007275=TAS, GO:0005634=IDA, GO:0003676=IEA, GO:0048588=IDA, GO:0005737=IDA, GO:0070534=IDA, GO:0071425=IDA, GO:0042787=IDA, GO:0008270=IEA, GO:0070936=IDA} developmental cell growth, hematopoietic stem cell proliferation, multicellular organismal development, protein K48-linked ubiquitination, protein K63-linked ubiquitination, protein polyubiquitination, protein ubiquitination involved in ubiquitin-dependent protein catabolic process, ubiquitin-dependent protein catabolic process cytoplasm, nucleus nucleic acid binding, protein binding, ubiquitin-protein ligase activity, zinc ion binding Human UniProtKB:P68036 ARL1 LIFEdb UniProtKB {GO:0005802=GO_REF:0000024, GO:0031584=PMID:9624189, GO:0005794=GO_REF:0000054, GO:0007264=GO_REF:0000002, GO:0019904=PMID:14580338, GO:0003924=PMID:8798635, GO:0005525=PMID:9624189, GO:0046872=GO_REF:0000037, GO:0006184=PMID:8798635, GO:0005622=GO_REF:0000002, GO:0005737=GO_REF:0000024, GO:0000139=GO_REF:0000039, GO:0034067=PMID:19224922, GO:0007030=GO_REF:0000024, GO:0042147=PMID:19224922, GO:0048193=GO_REF:0000019, GO:0009404=PMID:9624189, GO:0008047=PMID:9624189} P40616 ADP-ribosylation factor-like protein 1 protein 20100607 {GO:0005802=ISS, GO:0031584=IDA, GO:0005794=IDA, GO:0007264=IEA, GO:0019904=IPI, GO:0003924=IDA, GO:0005525=IDA, GO:0046872=IEA, GO:0006184=IDA, GO:0005622=IEA, GO:0005737=ISS, GO:0000139=IEA, GO:0034067=IMP, GO:0007030=ISS, GO:0042147=IMP, GO:0048193=IEA, GO:0009404=IDA, GO:0008047=IDA} GTP catabolic process, Golgi organization, Golgi vesicle transport, activation of phospholipase D activity, protein localization to Golgi apparatus, retrograde transport, endosome to Golgi, small GTPase mediated signal transduction, toxin metabolic process Golgi apparatus, Golgi membrane, cytoplasm, intracellular, trans-Golgi network GTP binding, GTPase activity, enzyme activator activity, metal ion binding, protein domain specific binding Human ARL10 UniProtKB UniProtKB {GO:0005622=GO_REF:0000002, GO:0007264=GO_REF:0000002, GO:0005525=GO_REF:0000037} Q8N8L6 ADP-ribosylation factor-like protein 10 protein 20130413 {GO:0005622=IEA, GO:0007264=IEA, GO:0005525=IEA} small GTPase mediated signal transduction intracellular GTP binding Human UniProtKB-KW:KW-0342 ARL11 IntAct UniProtKB {GO:0005515=PMID:19060904, GO:0005622=GO_REF:0000002, GO:0007264=GO_REF:0000002, GO:0005525=GO_REF:0000037} Q969Q4 ADP-ribosylation factor-like protein 11 protein 20130415 {GO:0005515=IPI, GO:0005622=IEA, GO:0007264=IEA, GO:0005525=IEA} small GTPase mediated signal transduction intracellular GTP binding, protein binding Human UniProtKB:Q15645 ARL13A UniProtKB UniProtKB {GO:0005622=GO_REF:0000002, GO:0007264=GO_REF:0000002, GO:0005525=GO_REF:0000037} Q5H913 ADP-ribosylation factor-like protein 13A protein 20130413 {GO:0005622=IEA, GO:0007264=IEA, GO:0005525=IEA} small GTPase mediated signal transduction intracellular GTP binding Human UniProtKB-KW:KW-0342 ARL13B UniProtKB UniProtKB {GO:0005515=PMID:20643351, GO:0005929=GO_REF:0000019, GO:0007368=GO_REF:0000019, GO:0007264=GO_REF:0000002, GO:0009953=GO_REF:0000019, GO:0005525=GO_REF:0000037} Q3SXY8 ADP-ribosylation factor-like protein 13B protein 20120708 {GO:0005515=IPI, GO:0005929=IEA, GO:0007368=IEA, GO:0007264=IEA, GO:0009953=IEA, GO:0005525=IEA} determination of left/right symmetry, dorsal/ventral pattern formation, small GTPase mediated signal transduction cilium GTP binding, protein binding Human UniProtKB:Q9D9W1 ARL14 IntAct UniProtKB {GO:0005515=PMID:21458045, GO:0007264=GO_REF:0000002, GO:0016023=GO_REF:0000039, GO:0005525=GO_REF:0000037} Q8N4G2 ADP-ribosylation factor-like protein 14 protein 20130415 {GO:0005515=IPI, GO:0007264=IEA, GO:0016023=IEA, GO:0005525=IEA} small GTPase mediated signal transduction cytoplasmic membrane-bounded vesicle GTP binding, protein binding Human UniProtKB:Q8N8R7 ARL15 UniProtKB UniProtKB {GO:0005622=GO_REF:0000002, GO:0007264=GO_REF:0000002, GO:0005525=GO_REF:0000037} Q9NXU5 ADP-ribosylation factor-like protein 15 protein 20130413 {GO:0005622=IEA, GO:0007264=IEA, GO:0005525=IEA} small GTPase mediated signal transduction intracellular GTP binding Human UniProtKB-KW:KW-0342 ARL16 UniProtKB UniProtKB {GO:0005622=GO_REF:0000002, GO:0007264=GO_REF:0000002, GO:0005525=GO_REF:0000037} Q0P5N6 ADP-ribosylation factor-like protein 16 protein 20130413 {GO:0005622=IEA, GO:0007264=IEA, GO:0005525=IEA} small GTPase mediated signal transduction intracellular GTP binding Human UniProtKB-KW:KW-0342 ARL17A UniProtKB UniProtKB {GO:0005622=GO_REF:0000002, GO:0005794=GO_REF:0000039, GO:0007264=GO_REF:0000002, GO:0016192=GO_REF:0000037, GO:0015031=GO_REF:0000037, GO:0005525=GO_REF:0000037} Q8IVW1 ADP-ribosylation factor-like protein 17 protein 20130413 {GO:0005622=IEA, GO:0005794=IEA, GO:0007264=IEA, GO:0016192=IEA, GO:0015031=IEA, GO:0005525=IEA} protein transport, small GTPase mediated signal transduction, vesicle-mediated transport Golgi apparatus, intracellular GTP binding Human UniProtKB-SubCell:SL-0132 ARL17B UniProtKB UniProtKB {GO:0005622=GO_REF:0000002, GO:0007264=GO_REF:0000002, GO:0005525=GO_REF:0000038} I3L3L1 ADP-ribosylation factor-like protein 17 protein 20130413 {GO:0005622=IEA, GO:0007264=IEA, GO:0005525=IEA} small GTPase mediated signal transduction intracellular GTP binding Human UniProtKB-KW:KW-0342 ARL2 GOC UniProtKB {GO:0005515=PMID:19368893, GO:0031116=PMID:20740604, GO:0005813=PMID:16525022, GO:0007264=GO_REF:0000002, GO:0010811=GO_REF:0000024, GO:0031113=PMID:16525022, GO:0003924=PMID:10831612, GO:0005634=PMID:18234692, GO:0005525=PMID:10831612, GO:0016328=GO_REF:0000024, GO:0006184=PMID:10831612, GO:0051297=PMID:16525022, GO:0005622=GO_REF:0000002, GO:0005758=PMID:11809823, GO:0007049=GO_REF:0000037, GO:0070830=GO_REF:0000024, GO:0007021=PMID:10831612, GO:0051457=PMID:18234692, GO:0005095=PMID:10831612, GO:0019003=GO_REF:0000019, GO:0034260=PMID:10831612} P36404 ADP-ribosylation factor-like protein 2 protein 20130413 {GO:0005515=IPI, GO:0031116=IDA, GO:0005813=IDA, GO:0007264=IEA, GO:0010811=ISS, GO:0031113=IMP, GO:0003924=IMP, GO:0005634=IDA, GO:0005525=IMP, GO:0016328=ISS, GO:0006184=IMP, GO:0051297=IMP, GO:0005622=IEA, GO:0005758=IDA, GO:0007049=IEA, GO:0070830=ISS, GO:0007021=TAS, GO:0051457=IDA, GO:0005095=TAS, GO:0019003=IEA, GO:0034260=IDA} GTP catabolic process, cell cycle, centrosome organization, maintenance of protein location in nucleus, negative regulation of GTPase activity, positive regulation of cell-substrate adhesion, positive regulation of microtubule polymerization, regulation of microtubule polymerization, small GTPase mediated signal transduction, tight junction assembly, tubulin complex assembly centrosome, intracellular, lateral plasma membrane, mitochondrial intermembrane space, nucleus GDP binding, GTP binding, GTPase activity, GTPase inhibitor activity, protein binding Human ARL2BP PINC UniProtKB {GO:0005515=PMID:19368893, GO:0007165=PMID:10488091, GO:0005758=PMID:11809823, GO:0005083=PMID:10488091, GO:0005813=PMID:16525022, GO:0051457=PMID:18234692, GO:0042517=PMID:18234692, GO:0003713=PMID:18234692, GO:0005819=GO_REF:0000039, GO:0030496=PMID:16525022, GO:0005634=GO_REF:0000039} Q9Y2Y0 ADP-ribosylation factor-like protein 2-binding protein protein 20030904 {GO:0005515=IPI, GO:0007165=TAS, GO:0005758=IDA, GO:0005083=TAS, GO:0005813=IDA, GO:0051457=IMP, GO:0042517=IMP, GO:0003713=IMP, GO:0005819=IEA, GO:0030496=IDA, GO:0005634=IEA} maintenance of protein location in nucleus, positive regulation of tyrosine phosphorylation of Stat3 protein, signal transduction centrosome, midbody, mitochondrial intermembrane space, nucleus, spindle protein binding, small GTPase regulator activity, transcription coactivator activity Human ARL3 HPA UniProtKB {GO:0005515=PMID:22085962, GO:0008017=PMID:12417528, GO:0005881=PMID:12417528, GO:0042461=GO_REF:0000024, GO:0005886=GO_REF:0000052, GO:0007264=PMID:22085962, GO:0003924=GO_REF:0000019, GO:0005634=GO_REF:0000052, GO:0015031=GO_REF:0000037, GO:0046872=GO_REF:0000037, GO:0000910=PMID:16525022, GO:0005737=GO_REF:0000052, GO:0042073=GO_REF:0000019, GO:0005876=PMID:16525022, GO:0005813=PMID:16525022, GO:0005794=GO_REF:0000052, GO:0001822=GO_REF:0000024, GO:0005730=GO_REF:0000052, GO:0030496=PMID:16525022, GO:0072372=PMID:16525022, GO:0005525=PMID:22085962, GO:0007049=GO_REF:0000037, GO:0000139=GO_REF:0000039, GO:0060271=PMID:22085962, GO:0032391=PMID:12417528, GO:0019003=PMID:18588884} P36405 ADP-ribosylation factor-like protein 3 protein 20110516 {GO:0005515=IPI, GO:0008017=IDA, GO:0005881=IDA, GO:0042461=ISS, GO:0005886=IDA, GO:0007264=IDA, GO:0003924=IEA, GO:0005634=IDA, GO:0015031=IEA, GO:0046872=IEA, GO:0000910=IMP, GO:0005737=IDA, GO:0042073=IEA, GO:0005876=IDA, GO:0005813=IDA, GO:0005794=IDA, GO:0001822=ISS, GO:0005730=IDA, GO:0030496=IDA, GO:0072372=IDA, GO:0005525=IDA, GO:0007049=IEA, GO:0000139=IEA, GO:0060271=IMP, GO:0032391=IDA, GO:0019003=IDA} cell cycle, cilium morphogenesis, cytokinesis, intraflagellar transport, kidney development, photoreceptor cell development, protein transport, small GTPase mediated signal transduction Golgi apparatus, Golgi membrane, centrosome, cytoplasm, cytoplasmic microtubule, midbody, nucleolus, nucleus, photoreceptor connecting cilium, plasma membrane, primary cilium, spindle microtubule GDP binding, GTP binding, GTPase activity, metal ion binding, microtubule binding, protein binding Human ARL4A UniProtKB UniProtKB {GO:0005515=PMID:17398095, GO:0005737=GO_REF:0000039, GO:0005886=PMID:17398095, GO:0007264=GO_REF:0000002, GO:0050873=GO_REF:0000019, GO:0005730=PMID:10980193, GO:0005634=PMID:10980193, GO:0005525=PMID:10980193} P40617 ADP-ribosylation factor-like protein 4A protein 20101220 {GO:0005515=IPI, GO:0005737=IEA, GO:0005886=IDA, GO:0007264=IEA, GO:0050873=IEA, GO:0005730=IDA, GO:0005634=IDA, GO:0005525=IDA} brown fat cell differentiation, small GTPase mediated signal transduction cytoplasm, nucleolus, nucleus, plasma membrane GTP binding, protein binding Human UniProtKB:Q99418 ARL4C GOC UniProtKB {GO:0006184=PMID:10462049, GO:0005515=PMID:17398095, GO:0005737=GO_REF:0000052, GO:0005886=GO_REF:0000052, GO:0043014=PMID:19409876, GO:0007264=GO_REF:0000002, GO:0032456=PMID:19409876, GO:0003924=PMID:10462049, GO:0005634=PMID:10462049, GO:0030175=GO_REF:0000039, GO:0005525=GO_REF:0000037} P56559 ADP-ribosylation factor-like protein 4C protein 20130413 {GO:0006184=TAS, GO:0005515=IPI, GO:0005737=IDA, GO:0005886=IDA, GO:0043014=IDA, GO:0007264=IEA, GO:0032456=IDA, GO:0003924=TAS, GO:0005634=TAS, GO:0030175=IEA, GO:0005525=IEA} GTP catabolic process, endocytic recycling, small GTPase mediated signal transduction cytoplasm, filopodium, nucleus, plasma membrane GTP binding, GTPase activity, alpha-tubulin binding, protein binding Human ARL4D GOC UniProtKB {GO:0006184=PMID:7590735, GO:0005515=PMID:17398095, GO:0005737=PMID:17398095, GO:0009306=PMID:7590735, GO:0005886=PMID:17398095, GO:0007264=GO_REF:0000002, GO:0003924=PMID:7590735, GO:0005730=GO_REF:0000039, GO:0005525=GO_REF:0000037} P49703 ADP-ribosylation factor-like protein 4D protein 20130413 {GO:0006184=TAS, GO:0005515=IPI, GO:0005737=IDA, GO:0009306=TAS, GO:0005886=IDA, GO:0007264=IEA, GO:0003924=TAS, GO:0005730=IEA, GO:0005525=IEA} GTP catabolic process, protein secretion, small GTPase mediated signal transduction cytoplasm, nucleolus, plasma membrane GTP binding, GTPase activity, protein binding Human ARL5A UniProtKB UniProtKB {GO:0005622=GO_REF:0000002, GO:0007264=GO_REF:0000002, GO:0005525=GO_REF:0000037} Q9Y689 ADP-ribosylation factor-like protein 5A protein 20130413 {GO:0005622=IEA, GO:0007264=IEA, GO:0005525=IEA} small GTPase mediated signal transduction intracellular GTP binding Human UniProtKB-KW:KW-0342 ARL5B UniProtKB UniProtKB {GO:0005622=GO_REF:0000002, GO:0007264=GO_REF:0000002, GO:0005525=GO_REF:0000037} Q96KC2 ADP-ribosylation factor-like protein 5B protein 20130413 {GO:0005622=IEA, GO:0007264=IEA, GO:0005525=IEA} small GTPase mediated signal transduction intracellular GTP binding Human UniProtKB-KW:KW-0342 ARL6 BHF-UCL UniProtKB {GO:0007368=GO_REF:0000024, GO:0051258=GO_REF:0000024, GO:0060170=GO_REF:0000039, GO:0034464=GO_REF:0000024, GO:0007264=GO_REF:0000002, GO:0005525=GO_REF:0000037, GO:0035085=GO_REF:0000024, GO:0032402=GO_REF:0000024, GO:0030117=GO_REF:0000024, GO:0046872=GO_REF:0000037, GO:0042384=GO_REF:0000024, GO:0005737=GO_REF:0000024, GO:0005543=GO_REF:0000024, GO:0016020=GO_REF:0000024, GO:0006612=GO_REF:0000024, GO:0005879=GO_REF:0000024, GO:0045444=GO_REF:0000019, GO:0005932=GO_REF:0000039, GO:0016055=PMID:20207729, GO:0007601=GO_REF:0000037} Q9H0F7 ADP-ribosylation factor-like protein 6 protein 20080517 {GO:0007368=ISS, GO:0051258=ISS, GO:0060170=IEA, GO:0034464=ISS, GO:0007264=IEA, GO:0005525=IEA, GO:0035085=ISS, GO:0032402=ISS, GO:0030117=ISS, GO:0046872=IEA, GO:0042384=ISS, GO:0005737=ISS, GO:0005543=ISS, GO:0016020=ISS, GO:0006612=ISS, GO:0005879=ISS, GO:0045444=IEA, GO:0005932=IEA, GO:0016055=IMP, GO:0007601=IEA} Wnt receptor signaling pathway, cilium assembly, determination of left/right symmetry, fat cell differentiation, melanosome transport, protein polymerization, protein targeting to membrane, small GTPase mediated signal transduction, visual perception BBSome, axonemal microtubule, cilium axoneme, cilium membrane, cytoplasm, membrane, membrane coat, microtubule basal body GTP binding, metal ion binding, phospholipid binding Human UniProtKB:Q5M9P8 ARL6IP1 HPA UniProtKB {GO:0005515=PMID:19060904, GO:0005784=GO_REF:0000019, GO:0005783=GO_REF:0000052, GO:0006613=GO_REF:0000019, GO:0016021=GO_REF:0000019, GO:0005829=GO_REF:0000019} Q15041 ADP-ribosylation factor-like protein 6-interacting protein 1 protein 20111111 {GO:0005515=IPI, GO:0005784=IEA, GO:0005783=IDA, GO:0006613=IEA, GO:0016021=IEA, GO:0005829=IEA} cotranslational protein targeting to membrane Sec61 translocon complex, cytosol, endoplasmic reticulum, integral to membrane protein binding Human ARL6IP4 IntAct UniProtKB {GO:0005515=PMID:20098747, GO:0008380=PMID:10708573, GO:0005634=PMID:10708573} Q66PJ3 ADP-ribosylation factor-like protein 6-interacting protein 4 protein 20130415 {GO:0005515=IPI, GO:0008380=TAS, GO:0005634=TAS} RNA splicing nucleus protein binding Human UniProtKB:Q9Y6K9 ARL6IP5 HPA UniProtKB {GO:0015813=GO_REF:0000024, GO:0005737=GO_REF:0000019, GO:0016020=GO_REF:0000019, GO:0005783=GO_REF:0000052, GO:0005789=GO_REF:0000039, GO:0016021=GO_REF:0000037, GO:0008022=GO_REF:0000019, GO:0051051=GO_REF:0000019} O75915 PRA1 family protein 3 protein 20101115 {GO:0015813=ISS, GO:0005737=IEA, GO:0016020=IEA, GO:0005783=IDA, GO:0005789=IEA, GO:0016021=IEA, GO:0008022=IEA, GO:0051051=IEA} L-glutamate transport, negative regulation of transport cytoplasm, endoplasmic reticulum, endoplasmic reticulum membrane, integral to membrane, membrane protein C-terminus binding Human ARL6IP6 UniProtKB UniProtKB {GO:0016021=GO_REF:0000037} Q8N6S5 ADP-ribosylation factor-like protein 6-interacting protein 6 protein 20130413 {GO:0016021=IEA} integral to membrane Human UniProtKB-KW:KW-0812 ARL8A GOC UniProtKB {GO:0007264=GO_REF:0000002, GO:0043014=PMID:15331635, GO:0003924=PMID:15331635, GO:0048487=PMID:15331635, GO:0030496=PMID:15331635, GO:0005765=GO_REF:0000039, GO:0005525=PMID:15331635, GO:0051233=PMID:15331635, GO:0006184=PMID:15331635, GO:0007067=GO_REF:0000037, GO:0005737=PMID:15331635, GO:0007059=PMID:14871887, GO:0031902=GO_REF:0000039, GO:0051301=GO_REF:0000037} Q96BM9 ADP-ribosylation factor-like protein 8A protein 20130413 {GO:0007264=IEA, GO:0043014=ISS, GO:0003924=NAS, GO:0048487=ISS, GO:0030496=IDA, GO:0005765=IEA, GO:0005525=IDA, GO:0051233=IDA, GO:0006184=NAS, GO:0007067=IEA, GO:0005737=IDA, GO:0007059=ISS, GO:0031902=IEA, GO:0051301=IEA} GTP catabolic process, cell division, chromosome segregation, mitosis, small GTPase mediated signal transduction cytoplasm, late endosome membrane, lysosomal membrane, midbody, spindle midzone GTP binding, GTPase activity, alpha-tubulin binding, beta-tubulin binding Human ARL8B GOC UniProtKB {GO:0007264=GO_REF:0000002, GO:0043014=PMID:15331635, GO:0048487=PMID:15331635, GO:0003924=PMID:15331635, GO:0030496=PMID:15331635, GO:0005525=PMID:15331635, GO:0005765=GO_REF:0000039, GO:0051233=PMID:15331635, GO:0006184=PMID:15331635, GO:0005622=GO_REF:0000002, GO:0007049=GO_REF:0000037, GO:0005737=PMID:15331635, GO:0007059=PMID:14871887, GO:0031902=GO_REF:0000039, GO:0019003=PMID:15331635, GO:0051301=GO_REF:0000037} Q9NVJ2 ADP-ribosylation factor-like protein 8B protein 20130413 {GO:0007264=IEA, GO:0043014=IDA, GO:0048487=IDA, GO:0003924=NAS, GO:0030496=IDA, GO:0005525=IDA, GO:0005765=IEA, GO:0051233=IDA, GO:0006184=NAS, GO:0005622=IEA, GO:0007049=IEA, GO:0005737=IDA, GO:0007059=IMP, GO:0031902=IEA, GO:0019003=IDA, GO:0051301=IEA} GTP catabolic process, cell cycle, cell division, chromosome segregation, small GTPase mediated signal transduction cytoplasm, intracellular, late endosome membrane, lysosomal membrane, midbody, spindle midzone GDP binding, GTP binding, GTPase activity, alpha-tubulin binding, beta-tubulin binding Human ARMC1 ENSEMBL UniProtKB {GO:0005739=GO_REF:0000019, GO:0046872=GO_REF:0000002, GO:0030001=GO_REF:0000002} Q9NVT9 Armadillo repeat-containing protein 1 protein 20130413 {GO:0005739=IEA, GO:0046872=IEA, GO:0030001=IEA} metal ion transport mitochondrion metal ion binding Human Ensembl:ENSMUSP00000029125 ARMC10 UniProtKB UniProtKB {GO:0005739=GO_REF:0000019, GO:0005789=GO_REF:0000039, GO:0016021=GO_REF:0000037, GO:0040008=GO_REF:0000037} Q8N2F6 Armadillo repeat-containing protein 10 protein 20130413 {GO:0005739=IEA, GO:0005789=IEA, GO:0016021=IEA, GO:0040008=IEA} regulation of growth endoplasmic reticulum membrane, integral to membrane, mitochondrion Human UniProtKB-SubCell:SL-0097 ARMC4 null null {} null null null null {} null null null ARMC5 null null {} null null null null {} null null null ARMC6 null null {} null null null null {} null null null ARMC7 null null {} null null null null {} null null null ARMC8 null null {} null null null null {} null null null ARMC9 null null {} null null null null {} null null null ARMCX1 UniProtKB UniProtKB {GO:0016021=GO_REF:0000037} Q9P291 Armadillo repeat-containing X-linked protein 1 protein 20130413 {GO:0016021=IEA} integral to membrane Human UniProtKB-KW:KW-0812 ARMCX2 UniProtKB UniProtKB {GO:0016021=GO_REF:0000037} Q7L311 Armadillo repeat-containing X-linked protein 2 protein 20130413 {GO:0016021=IEA} integral to membrane Human UniProtKB-KW:KW-0812 ARMCX3 ENSEMBL UniProtKB {GO:0045944=GO_REF:0000019, GO:0034613=GO_REF:0000019, GO:0031307=GO_REF:0000019} Q9UH62 Armadillo repeat-containing X-linked protein 3 protein 20130413 {GO:0045944=IEA, GO:0034613=IEA, GO:0031307=IEA} cellular protein localization, positive regulation of transcription from RNA polymerase II promoter integral to mitochondrial outer membrane Human Ensembl:ENSMUSP00000084097 ARMCX5 null null {} null null null null {} null null null ARNT BHF-UCL UniProtKB {GO:0005515=PMID:21620138, GO:0030949=PMID:8756616, GO:0003700=PMID:1317062, GO:0003705=PMID:7539918, GO:0061418=Reactome:REACT_120815, GO:0005634=GO_REF:0000052, GO:0030154=GO_REF:0000019, GO:0005737=GO_REF:0000019, GO:0046886=PMID:1448077, GO:0045944=GO_REF:0000019, GO:0046983=GO_REF:0000002, GO:0033235=GO_REF:0000019, GO:0004874=GO_REF:0000019, GO:0042789=PMID:7539918, GO:0004871=GO_REF:0000002, GO:0045821=PMID:8089148, GO:0005667=GO_REF:0000002, GO:0001666=PMID:8756616, GO:0046982=PMID:9079689, GO:0003713=GO_REF:0000019, GO:0001892=GO_REF:0000019, GO:0071456=Reactome:REACT_121311, GO:0043619=PMID:8089148, GO:0033554=Reactome:REACT_120956, GO:0010575=PMID:8756616, GO:0003677=GO_REF:0000038, GO:0006351=PMID:1317062, GO:0043565=PMID:7539918, GO:0001938=PMID:8756616, GO:0045648=PMID:1448077, GO:0005654=Reactome:REACT_121202, GO:0017162=PMID:9079689, GO:0045893=PMID:8089148, GO:0008134=PMID:10692439} P27540 Aryl hydrocarbon receptor nuclear translocator protein 20110609 {GO:0005515=IPI, GO:0030949=IC, GO:0003700=TAS, GO:0003705=IDA, GO:0061418=TAS, GO:0005634=IDA, GO:0030154=IEA, GO:0005737=IEA, GO:0046886=IDA, GO:0045944=IEA, GO:0046983=IEA, GO:0033235=IEA, GO:0004874=IEA, GO:0042789=IC, GO:0004871=IEA, GO:0045821=IC, GO:0005667=IEA, GO:0001666=IDA, GO:0046982=IPI, GO:0003713=IEA, GO:0001892=IEA, GO:0071456=TAS, GO:0043619=IDA, GO:0033554=TAS, GO:0010575=IDA, GO:0003677=IEA, GO:0006351=TAS, GO:0043565=IDA, GO:0001938=IC, GO:0045648=IC, GO:0005654=TAS, GO:0017162=IPI, GO:0045893=IDA, GO:0008134=IPI} cell differentiation, cellular response to hypoxia, cellular response to stress, embryonic placenta development, mRNA transcription from RNA polymerase II promoter, positive regulation of endothelial cell proliferation, positive regulation of erythrocyte differentiation, positive regulation of glycolysis, positive regulation of hormone biosynthetic process, positive regulation of protein sumoylation, positive regulation of transcription from RNA polymerase II promoter, positive regulation of transcription, DNA-dependent, positive regulation of vascular endothelial growth factor receptor signaling pathway, positive regulation vascular endothelial growth factor production, regulation of transcription from RNA polymerase II promoter in response to hypoxia, regulation of transcription from RNA polymerase II promoter in response to oxidative stress, response to hypoxia, transcription, DNA-dependent cytoplasm, nucleoplasm, nucleus, transcription factor complex DNA binding, RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity, aryl hydrocarbon receptor activity, aryl hydrocarbon receptor binding, protein binding, protein dimerization activity, protein heterodimerization activity, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, signal transducer activity, transcription coactivator activity, transcription factor binding Human UniProtKB:Q9Y5J3 ARNT2 MGI UniProtKB {GO:0001666=PMID:12239177, GO:0005667=GO_REF:0000019, GO:0006355=PMID:11782478, GO:0008284=GO_REF:0000019, GO:0043066=GO_REF:0000019, GO:0003700=GO_REF:0000024, GO:0046982=PMID:12239177, GO:0005634=PMID:12239177, GO:0007417=GO_REF:0000024, GO:0001701=GO_REF:0000024, GO:0003677=GO_REF:0000019, GO:0006351=GO_REF:0000037, GO:0005737=GO_REF:0000002, GO:0045944=GO_REF:0000019, GO:0004871=GO_REF:0000002, GO:0017162=GO_REF:0000024, GO:0045893=GO_REF:0000024, GO:0032355=GO_REF:0000019} Q9HBZ2 Aryl hydrocarbon receptor nuclear translocator 2 protein 20031023 {GO:0001666=IDA, GO:0005667=IEA, GO:0006355=IDA, GO:0008284=IEA, GO:0043066=IEA, GO:0003700=ISS, GO:0046982=IPI, GO:0005634=IDA, GO:0007417=ISS, GO:0001701=ISS, GO:0003677=IEA, GO:0006351=IEA, GO:0005737=IEA, GO:0045944=IEA, GO:0004871=IEA, GO:0017162=ISS, GO:0045893=ISS, GO:0032355=IEA} central nervous system development, in utero embryonic development, negative regulation of apoptotic process, positive regulation of cell proliferation, positive regulation of transcription from RNA polymerase II promoter, positive regulation of transcription, DNA-dependent, regulation of transcription, DNA-dependent, response to estradiol stimulus, response to hypoxia, transcription, DNA-dependent cytoplasm, nucleus, transcription factor complex DNA binding, aryl hydrocarbon receptor binding, protein heterodimerization activity, sequence-specific DNA binding transcription factor activity, signal transducer activity Human ARNTL BHF-UCL UniProtKB {GO:0005667=PMID:9576906, GO:0006355=GO_REF:0000024, GO:0003700=GO_REF:0000002, GO:0001190=GO_REF:0000019, GO:0042176=GO_REF:0000019, GO:0046982=GO_REF:0000019, GO:0000982=GO_REF:0000024, GO:0051879=PMID:9079689, GO:0043425=GO_REF:0000019, GO:0003677=PMID:9576906, GO:0006351=GO_REF:0000038, GO:0032922=GO_REF:0000024, GO:0016604=GO_REF:0000019, GO:0005737=GO_REF:0000002, GO:0045944=PMID:20093779, GO:0046983=GO_REF:0000002, GO:0007623=PMID:9616112, GO:0017162=PMID:9079689, GO:0004871=GO_REF:0000002, GO:0000060=GO_REF:0000019} O00327 Aryl hydrocarbon receptor nuclear translocator-like protein 1 protein 20111105 {GO:0005667=IPI, GO:0006355=ISS, GO:0003700=IEA, GO:0001190=IEA, GO:0042176=IEA, GO:0046982=IEA, GO:0000982=ISS, GO:0051879=IDA, GO:0043425=IEA, GO:0003677=IGI, GO:0006351=IEA, GO:0032922=ISS, GO:0016604=IEA, GO:0005737=IEA, GO:0045944=IDA, GO:0046983=IEA, GO:0007623=TAS, GO:0017162=IPI, GO:0004871=IEA, GO:0000060=IEA} circadian regulation of gene expression, circadian rhythm, positive regulation of transcription from RNA polymerase II promoter, protein import into nucleus, translocation, regulation of protein catabolic process, regulation of transcription, DNA-dependent, transcription, DNA-dependent cytoplasm, nuclear body, transcription factor complex DNA binding, Hsp90 protein binding, RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity, RNA polymerase II transcription factor binding transcription factor activity involved in positive regulation of transcription, aryl hydrocarbon receptor binding, bHLH transcription factor binding, protein dimerization activity, protein heterodimerization activity, sequence-specific DNA binding transcription factor activity, signal transducer activity Human UniProtKB:Q9WTL8 ARNTL2 BHF-UCL UniProtKB {GO:0005667=GO_REF:0000002, GO:0006355=PMID:11018023, GO:0003700=PMID:12055078, GO:0006357=PMID:12055078, GO:0000982=PMID:15147242, GO:0005634=PMID:12055078, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000038, GO:0005737=GO_REF:0000002, GO:0009649=PMID:11018023, GO:0045944=PMID:15147242, GO:0046983=GO_REF:0000002, GO:0007623=PMID:10864977, GO:0004871=GO_REF:0000002} Q8WYA1 Aryl hydrocarbon receptor nuclear translocator-like protein 2 protein 20111104 {GO:0005667=IEA, GO:0006355=NAS, GO:0003700=IDA, GO:0006357=IDA, GO:0000982=IDA, GO:0005634=IDA, GO:0003677=IEA, GO:0006351=IEA, GO:0005737=IEA, GO:0009649=NAS, GO:0045944=IDA, GO:0046983=IEA, GO:0007623=IDA, GO:0004871=IEA} circadian rhythm, entrainment of circadian clock, positive regulation of transcription from RNA polymerase II promoter, regulation of transcription from RNA polymerase II promoter, regulation of transcription, DNA-dependent, transcription, DNA-dependent cytoplasm, nucleus, transcription factor complex DNA binding, RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity, protein dimerization activity, sequence-specific DNA binding transcription factor activity, signal transducer activity Human ARPC1A Reactome UniProtKB {GO:0030036=PMID:8978670, GO:0030833=GO_REF:0000002, GO:0045087=Reactome:REACT_6802, GO:0003779=GO_REF:0000037, GO:0015629=PMID:8978670, GO:0005856=GO_REF:0000002, GO:0038096=Reactome:REACT_160123, GO:0005829=Reactome:REACT_160291} Q92747 Actin-related protein 2/3 complex subunit 1A protein 20130213 {GO:0030036=TAS, GO:0030833=IEA, GO:0045087=TAS, GO:0003779=IEA, GO:0015629=TAS, GO:0005856=IEA, GO:0038096=TAS, GO:0005829=TAS} Fc-gamma receptor signaling pathway involved in phagocytosis, actin cytoskeleton organization, innate immune response, regulation of actin filament polymerization actin cytoskeleton, cytoskeleton, cytosol actin binding Human ARPC1B PINC UniProtKB {GO:0005737=GO_REF:0000037, GO:0030833=GO_REF:0000002, GO:0005885=PMID:9230079, GO:0005200=PMID:9230079, GO:0006928=PMID:9230079, GO:0003779=GO_REF:0000037, GO:0015629=PMID:9230079, GO:0005856=GO_REF:0000002} O15143 Actin-related protein 2/3 complex subunit 1B protein 20030904 {GO:0005737=IEA, GO:0030833=IEA, GO:0005885=TAS, GO:0005200=TAS, GO:0006928=TAS, GO:0003779=IEA, GO:0015629=TAS, GO:0005856=IEA} cellular component movement, regulation of actin filament polymerization Arp2/3 protein complex, actin cytoskeleton, cytoplasm, cytoskeleton actin binding, structural constituent of cytoskeleton Human ARPC2 HPA UniProtKB {GO:0005515=PMID:17350576, GO:0035650=GO_REF:0000019, GO:0005794=GO_REF:0000052, GO:0005886=GO_REF:0000019, GO:0005885=PMID:9230079, GO:0006928=PMID:9230079, GO:0071933=GO_REF:0000019, GO:0003779=GO_REF:0000037, GO:0042995=GO_REF:0000039, GO:0015629=PMID:9230079, GO:0005829=Reactome:REACT_160291, GO:0005737=GO_REF:0000052, GO:0030833=GO_REF:0000002, GO:0030838=GO_REF:0000019, GO:1900026=GO_REF:0000019, GO:0045087=Reactome:REACT_6802, GO:0005200=PMID:9230079, GO:0019894=GO_REF:0000019, GO:0005856=GO_REF:0000002, GO:0038096=Reactome:REACT_160123, GO:0005925=GO_REF:0000019, GO:0031252=GO_REF:0000019, GO:0005768=GO_REF:0000019} O15144 Actin-related protein 2/3 complex subunit 2 protein 20080818 {GO:0005515=IPI, GO:0035650=IEA, GO:0005794=IDA, GO:0005886=IEA, GO:0005885=TAS, GO:0006928=TAS, GO:0071933=IEA, GO:0003779=IEA, GO:0042995=IEA, GO:0015629=TAS, GO:0005829=TAS, GO:0005737=IDA, GO:0030833=IEA, GO:0030838=IEA, GO:1900026=IEA, GO:0045087=TAS, GO:0005200=TAS, GO:0019894=IEA, GO:0005856=IEA, GO:0038096=TAS, GO:0005925=IEA, GO:0031252=IEA, GO:0005768=IEA} Fc-gamma receptor signaling pathway involved in phagocytosis, cellular component movement, innate immune response, positive regulation of actin filament polymerization, positive regulation of substrate adhesion-dependent cell spreading, regulation of actin filament polymerization Arp2/3 protein complex, Golgi apparatus, actin cytoskeleton, cell leading edge, cell projection, cytoplasm, cytoskeleton, cytosol, endosome, focal adhesion, plasma membrane AP-1 adaptor complex binding, Arp2/3 complex binding, actin binding, kinesin binding, protein binding, structural constituent of cytoskeleton Human ARPC3 Reactome UniProtKB {GO:0005515=PMID:11162547, GO:0034314=GO_REF:0000002, GO:0005885=GO_REF:0000002, GO:0045087=Reactome:REACT_6802, GO:0005200=PMID:9230079, GO:0006928=PMID:9230079, GO:0003779=GO_REF:0000037, GO:0015629=PMID:9230079, GO:0038096=Reactome:REACT_160123, GO:0030027=GO_REF:0000019, GO:0005829=Reactome:REACT_160291} O15145 Actin-related protein 2/3 complex subunit 3 protein 20130213 {GO:0005515=IPI, GO:0034314=IEA, GO:0005885=IEA, GO:0045087=TAS, GO:0005200=TAS, GO:0006928=TAS, GO:0003779=IEA, GO:0015629=TAS, GO:0038096=TAS, GO:0030027=IEA, GO:0005829=TAS} Arp2/3 complex-mediated actin nucleation, Fc-gamma receptor signaling pathway involved in phagocytosis, cellular component movement, innate immune response Arp2/3 protein complex, actin cytoskeleton, cytosol, lamellipodium actin binding, protein binding, structural constituent of cytoskeleton Human ARPC4 Reactome UniProtKB {GO:0005515=PMID:11162547, GO:0034314=GO_REF:0000002, GO:0051015=PMID:11162547, GO:0005885=PMID:11162547, GO:0045087=Reactome:REACT_6802, GO:0030041=GO_REF:0000002, GO:0042995=GO_REF:0000039, GO:0030674=PMID:11162547, GO:0038096=Reactome:REACT_160123, GO:0005829=Reactome:REACT_160291, GO:0045010=PMID:11162547} P59998 Actin-related protein 2/3 complex subunit 4 protein 20130213 {GO:0005515=IPI, GO:0034314=IEA, GO:0051015=NAS, GO:0005885=IDA, GO:0045087=TAS, GO:0030041=IEA, GO:0042995=IEA, GO:0030674=IPI, GO:0038096=TAS, GO:0005829=TAS, GO:0045010=NAS} Arp2/3 complex-mediated actin nucleation, Fc-gamma receptor signaling pathway involved in phagocytosis, actin filament polymerization, actin nucleation, innate immune response Arp2/3 protein complex, cell projection, cytosol actin filament binding, protein binding, protein binding, bridging Human ARPC5 Reactome UniProtKB {GO:0005515=PMID:11162547, GO:0030036=PMID:9359840, GO:0005885=PMID:9230079, GO:0006928=PMID:9230079, GO:0003779=GO_REF:0000037, GO:0015629=PMID:9230079, GO:0030027=GO_REF:0000019, GO:0005829=Reactome:REACT_160291, GO:0005737=PMID:9359840, GO:0030833=GO_REF:0000002, GO:0045087=Reactome:REACT_6802, GO:0005200=PMID:9230079, GO:0005856=GO_REF:0000002, GO:0038096=Reactome:REACT_160123} O15511 Actin-related protein 2/3 complex subunit 5 protein 20130213 {GO:0005515=IPI, GO:0030036=TAS, GO:0005885=TAS, GO:0006928=TAS, GO:0003779=IEA, GO:0015629=TAS, GO:0030027=IEA, GO:0005829=TAS, GO:0005737=TAS, GO:0030833=IEA, GO:0045087=TAS, GO:0005200=TAS, GO:0005856=IEA, GO:0038096=TAS} Fc-gamma receptor signaling pathway involved in phagocytosis, actin cytoskeleton organization, cellular component movement, innate immune response, regulation of actin filament polymerization Arp2/3 protein complex, actin cytoskeleton, cytoplasm, cytoskeleton, cytosol, lamellipodium actin binding, protein binding, structural constituent of cytoskeleton Human ARPC5L UniProtKB UniProtKB {GO:0005737=GO_REF:0000037, GO:0030833=GO_REF:0000002, GO:0003779=GO_REF:0000037, GO:0005856=GO_REF:0000039} Q9BPX5 Actin-related protein 2/3 complex subunit 5-like protein protein 20130413 {GO:0005737=IEA, GO:0030833=IEA, GO:0003779=IEA, GO:0005856=IEA} regulation of actin filament polymerization cytoplasm, cytoskeleton actin binding Human UniProtKB-SubCell:SL-0090 ARPP19 Reactome UniProtKB {GO:0004864=GO_REF:0000037, GO:0008601=GO_REF:0000024, GO:0045722=PMID:9653196, GO:0005102=PMID:9653196, GO:0015459=PMID:9653196, GO:0019212=GO_REF:0000024, GO:0005737=GO_REF:0000039, GO:0007067=PMID:21164014, GO:0000088=Reactome:REACT_765, GO:0046326=PMID:9653196, GO:0000086=PMID:21164014, GO:0000087=Reactome:REACT_910, GO:0005654=Reactome:REACT_150326, GO:0000278=Reactome:REACT_152, GO:0051721=GO_REF:0000024, GO:0051301=GO_REF:0000037} P56211 cAMP-regulated phosphoprotein 19 protein 20130301 {GO:0004864=IEA, GO:0008601=ISS, GO:0045722=IDA, GO:0005102=IDA, GO:0015459=IDA, GO:0019212=ISS, GO:0005737=IEA, GO:0007067=IMP, GO:0000088=TAS, GO:0046326=NAS, GO:0000086=IMP, GO:0000087=TAS, GO:0005654=TAS, GO:0000278=TAS, GO:0051721=ISS, GO:0051301=IEA} G2/M transition of mitotic cell cycle, M phase of mitotic cell cycle, cell division, mitosis, mitotic cell cycle, mitotic prophase, positive regulation of gluconeogenesis, positive regulation of glucose import cytoplasm, nucleoplasm phosphatase inhibitor activity, potassium channel regulator activity, protein phosphatase 2A binding, protein phosphatase inhibitor activity, protein phosphatase type 2A regulator activity, receptor binding Human ARPP21 UniProtKB UniProtKB {GO:0034605=GO_REF:0000019, GO:0003674=GO_REF:0000015, GO:0008150=GO_REF:0000015, GO:0005516=GO_REF:0000037, GO:0005737=GO_REF:0000039, GO:0005575=GO_REF:0000015, GO:0003676=GO_REF:0000002} Q9UBL0 cAMP-regulated phosphoprotein 21 protein 20061026 {GO:0034605=IEA, GO:0003674=ND, GO:0008150=ND, GO:0005516=IEA, GO:0005737=IEA, GO:0005575=ND, GO:0003676=IEA} biological_process, cellular response to heat cellular_component, cytoplasm calmodulin binding, molecular_function, nucleic acid binding Human ARR3 IntAct UniProtKB {GO:0005515=PMID:16189514, GO:0051219=GO_REF:0000019, GO:0007165=GO_REF:0000002, GO:0005737=PMID:8224247, GO:0045202=GO_REF:0000019, GO:0001932=GO_REF:0000019, GO:0002046=GO_REF:0000019, GO:0007601=GO_REF:0000037, GO:0006897=GO_REF:0000019, GO:0001750=GO_REF:0000019} P36575 Arrestin-C protein 20130415 {GO:0005515=IPI, GO:0051219=IEA, GO:0007165=IEA, GO:0005737=TAS, GO:0045202=IEA, GO:0001932=IEA, GO:0002046=IEA, GO:0007601=IEA, GO:0006897=IEA, GO:0001750=IEA} endocytosis, regulation of protein phosphorylation, signal transduction, visual perception cytoplasm, photoreceptor outer segment, synapse opsin binding, phosphoprotein binding, protein binding Human UniProtKB:Q96IT1 ARRB1 GOC UniProtKB {GO:0005515=PMID:21988832, GO:0032717=PMID:16378096, GO:0006366=PMID:16325578, GO:0044212=PMID:16325578, GO:0032715=PMID:16378096, GO:0005159=PMID:15878855, GO:0015031=GO_REF:0000037, GO:0005765=Reactome:REACT_19206, GO:0007219=Reactome:REACT_118859, GO:0031397=PMID:16378096, GO:0070374=PMID:10644702, GO:0000785=PMID:16325578, GO:0043027=GO_REF:0000019, GO:0031625=PMID:15878855, GO:0006892=Reactome:REACT_11235, GO:0031434=GO_REF:0000019, GO:0030168=Reactome:REACT_798, GO:0002031=PMID:10521508, GO:0043547=PMID:15611106, GO:0016044=Reactome:REACT_11123, GO:0008134=PMID:16325578, GO:0090240=PMID:16325578, GO:0016567=PMID:15878855, GO:0005886=PMID:9924018, GO:0035025=PMID:15611106, GO:0043149=PMID:15611106, GO:0005634=PMID:16325578, GO:0031701=PMID:15611106, GO:0035066=PMID:16325578, GO:0032092=GO_REF:0000019, GO:0031143=GO_REF:0000039, GO:0005829=Reactome:REACT_23958, GO:0005737=PMID:15611106, GO:0033138=GO_REF:0000019, GO:0045944=PMID:16325578, GO:0030659=Reactome:REACT_19255, GO:0004402=PMID:16325578, GO:0004857=PMID:2163110, GO:0035774=GO_REF:0000019, GO:0005834=PMID:10823817, GO:0032088=PMID:16378096, GO:0031410=PMID:15611106, GO:0007165=GO_REF:0000002, GO:0005905=GO_REF:0000039, GO:0000139=Reactome:REACT_19391, GO:0007596=Reactome:REACT_604, GO:0043161=PMID:15878855, GO:0007602=GO_REF:0000019, GO:0005096=PMID:15611106} P49407 Beta-arrestin-1 protein 20130413 {GO:0005515=IPI, GO:0032717=IDA, GO:0006366=IMP, GO:0044212=IMP, GO:0032715=IDA, GO:0005159=IPI, GO:0015031=IEA, GO:0005765=TAS, GO:0007219=TAS, GO:0031397=IDA, GO:0070374=IDA, GO:0000785=IDA, GO:0043027=IEA, GO:0031625=IPI, GO:0006892=TAS, GO:0031434=IEA, GO:0030168=TAS, GO:0002031=IMP, GO:0043547=IMP, GO:0016044=TAS, GO:0008134=IPI, GO:0090240=IMP, GO:0016567=IMP, GO:0005886=TAS, GO:0035025=IMP, GO:0043149=IMP, GO:0005634=IDA, GO:0031701=IPI, GO:0035066=IMP, GO:0032092=IEA, GO:0031143=IEA, GO:0005829=TAS, GO:0005737=IDA, GO:0033138=IEA, GO:0045944=IMP, GO:0030659=TAS, GO:0004402=IDA, GO:0004857=TAS, GO:0035774=IEA, GO:0005834=TAS, GO:0032088=IDA, GO:0031410=IDA, GO:0007165=IEA, GO:0005905=IEA, GO:0000139=TAS, GO:0007596=TAS, GO:0043161=IMP, GO:0007602=IEA, GO:0005096=IMP} G-protein coupled receptor internalization, Notch signaling pathway, blood coagulation, cellular membrane organization, negative regulation of NF-kappaB transcription factor activity, negative regulation of interleukin-6 production, negative regulation of interleukin-8 production, negative regulation of protein ubiquitination, phototransduction, platelet activation, positive regulation of ERK1 and ERK2 cascade, positive regulation of GTPase activity, positive regulation of Rho protein signal transduction, positive regulation of histone H4 acetylation, positive regulation of histone acetylation, positive regulation of insulin secretion involved in cellular response to glucose stimulus, positive regulation of peptidyl-serine phosphorylation, positive regulation of protein binding, positive regulation of transcription from RNA polymerase II promoter, post-Golgi vesicle-mediated transport, proteasomal ubiquitin-dependent protein catabolic process, protein transport, protein ubiquitination, signal transduction, stress fiber assembly, transcription from RNA polymerase II promoter Golgi membrane, chromatin, coated pit, cytoplasm, cytoplasmic vesicle, cytoplasmic vesicle membrane, cytosol, heterotrimeric G-protein complex, lysosomal membrane, nucleus, plasma membrane, pseudopodium GTPase activator activity, angiotensin receptor binding, cysteine-type endopeptidase inhibitor activity involved in apoptotic process, enzyme inhibitor activity, histone acetyltransferase activity, insulin-like growth factor receptor binding, mitogen-activated protein kinase kinase binding, protein binding, transcription factor binding, transcription regulatory region DNA binding, ubiquitin protein ligase binding Human ARRB2 BHF-UCL UniProtKB {GO:0005515=PMID:19372219, GO:0006366=PMID:16820410, GO:0034122=GO_REF:0000019, GO:0032715=GO_REF:0000019, GO:0051928=GO_REF:0000019, GO:0032691=GO_REF:0000019, GO:0042699=GO_REF:0000019, GO:0050731=GO_REF:0000019, GO:0015031=GO_REF:0000037, GO:0032403=GO_REF:0000019, GO:0031623=PMID:12958365, GO:0031762=GO_REF:0000019, GO:0007219=Reactome:REACT_118859, GO:0045211=GO_REF:0000019, GO:0031398=PMID:19372219, GO:0007179=PMID:12958365, GO:0031397=PMID:16378096, GO:0070374=PMID:12582207, GO:0034260=GO_REF:0000019, GO:0031625=PMID:19372219, GO:0051019=GO_REF:0000019, GO:0019904=GO_REF:0000019, GO:0060765=PMID:19372219, GO:0030168=Reactome:REACT_798, GO:0032720=GO_REF:0000019, GO:0014069=GO_REF:0000019, GO:0002031=PMID:10644702, GO:0002032=PMID:12582207, GO:0031826=GO_REF:0000019, GO:0031691=GO_REF:0000019, GO:0031692=GO_REF:0000019, GO:0032226=GO_REF:0000019, GO:0007420=GO_REF:0000019, GO:0051897=GO_REF:0000019, GO:0016567=PMID:15878855, GO:0005886=PMID:18604210, GO:0005634=PMID:16820410, GO:0031701=PMID:15611106, GO:0031702=GO_REF:0000019, GO:0005829=Reactome:REACT_23960, GO:0016323=GO_REF:0000019, GO:0071889=GO_REF:0000019, GO:0005737=PMID:12958365, GO:0031748=GO_REF:0000019, GO:0007628=GO_REF:0000019, GO:0050965=GO_REF:0000019, GO:0001664=PMID:10644702, GO:0005102=PMID:18604210, GO:0032088=PMID:16378096, GO:0031410=PMID:12958365, GO:0043422=GO_REF:0000019, GO:0007165=GO_REF:0000002, GO:0032947=PMID:19372219, GO:0005905=GO_REF:0000039, GO:0034392=GO_REF:0000019, GO:0007596=Reactome:REACT_604, GO:0060326=PMID:15635042, GO:0032695=GO_REF:0000019, GO:0045953=PMID:18604210, GO:0016023=GO_REF:0000039, GO:0043161=PMID:15878855, GO:0002092=GO_REF:0000019} P32121 Beta-arrestin-2 protein 20120316 {GO:0005515=IPI, GO:0006366=IDA, GO:0034122=IEA, GO:0032715=IEA, GO:0051928=IEA, GO:0032691=IEA, GO:0042699=IEA, GO:0050731=IEA, GO:0015031=IEA, GO:0032403=IEA, GO:0031623=IDA, GO:0031762=IEA, GO:0007219=TAS, GO:0045211=IEA, GO:0031398=IGI, GO:0007179=IDA, GO:0031397=IDA, GO:0070374=IMP, GO:0034260=IEA, GO:0031625=IPI, GO:0051019=IEA, GO:0019904=IEA, GO:0060765=IDA, GO:0030168=TAS, GO:0032720=IEA, GO:0014069=IEA, GO:0002031=IDA, GO:0002032=IMP, GO:0031826=IEA, GO:0031691=IEA, GO:0031692=IEA, GO:0032226=IEA, GO:0007420=IEA, GO:0051897=IEA, GO:0016567=IMP, GO:0005886=IDA, GO:0005634=IDA, GO:0031701=IPI, GO:0031702=IEA, GO:0005829=TAS, GO:0016323=IEA, GO:0071889=IEA, GO:0005737=IDA, GO:0031748=IEA, GO:0007628=IEA, GO:0050965=IEA, GO:0001664=IPI, GO:0005102=IPI, GO:0032088=IDA, GO:0031410=IDA, GO:0043422=IEA, GO:0007165=IEA, GO:0032947=IDA, GO:0005905=IEA, GO:0034392=IEA, GO:0007596=TAS, GO:0060326=IMP, GO:0032695=IEA, GO:0045953=IMP, GO:0016023=IEA, GO:0043161=IMP, GO:0002092=IEA} G-protein coupled receptor internalization, Notch signaling pathway, adult walking behavior, blood coagulation, brain development, cell chemotaxis, desensitization of G-protein coupled receptor protein signaling pathway by arrestin, detection of temperature stimulus involved in sensory perception of pain, follicle-stimulating hormone signaling pathway, negative regulation of GTPase activity, negative regulation of NF-kappaB transcription factor activity, negative regulation of interleukin-1 beta production, negative regulation of interleukin-12 production, negative regulation of interleukin-6 production, negative regulation of natural killer cell mediated cytotoxicity, negative regulation of protein ubiquitination, negative regulation of smooth muscle cell apoptotic process, negative regulation of toll-like receptor signaling pathway, negative regulation of tumor necrosis factor production, platelet activation, positive regulation of ERK1 and ERK2 cascade, positive regulation of calcium ion transport, positive regulation of peptidyl-tyrosine phosphorylation, positive regulation of protein kinase B signaling cascade, positive regulation of protein ubiquitination, positive regulation of receptor internalization, positive regulation of synaptic transmission, dopaminergic, proteasomal ubiquitin-dependent protein catabolic process, protein transport, protein ubiquitination, receptor internalization, regulation of androgen receptor signaling pathway, signal transduction, transcription from RNA polymerase II promoter, transforming growth factor beta receptor signaling pathway basolateral plasma membrane, coated pit, cytoplasm, cytoplasmic membrane-bounded vesicle, cytoplasmic vesicle, cytosol, nucleus, plasma membrane, postsynaptic density, postsynaptic membrane 14-3-3 protein binding, D1 dopamine receptor binding, G-protein coupled receptor binding, alpha-1A adrenergic receptor binding, alpha-1B adrenergic receptor binding, angiotensin receptor binding, follicle-stimulating hormone receptor binding, mitogen-activated protein kinase binding, protein binding, protein complex binding, protein complex scaffold, protein domain specific binding, protein kinase B binding, receptor binding, type 1 angiotensin receptor binding, type 2A serotonin receptor binding, ubiquitin protein ligase binding Human UniProtKB:Q08499-6 ARRDC1 null null {} null null null null {} null null null ARRDC2 InterPro UniProtKB {GO:0007165=GO_REF:0000002} Q8TBH0 Arrestin domain-containing protein 2 protein 20130413 {GO:0007165=IEA} signal transduction Human InterPro:IPR014752 ARRDC3 MGI UniProtKB {GO:0005737=GO_REF:0000039, GO:0001659=GO_REF:0000019, GO:0044252=GO_REF:0000019, GO:0031699=PMID:21982743, GO:0090327=GO_REF:0000019, GO:0060613=GO_REF:0000019, GO:0031651=GO_REF:0000019, GO:0071879=GO_REF:0000019} Q96B67 Arrestin domain-containing protein 3 protein 20121004 {GO:0005737=IEA, GO:0001659=IEA, GO:0044252=IEA, GO:0031699=IDA, GO:0090327=IEA, GO:0060613=IEA, GO:0031651=IEA, GO:0071879=IEA} fat pad development, negative regulation of heat generation, negative regulation of locomotion involved in locomotory behavior, negative regulation of multicellular organismal metabolic process, positive regulation of adrenergic receptor signaling pathway, temperature homeostasis cytoplasm beta-3 adrenergic receptor binding Human ARRDC4 null null {} null null null null {} null null null ARSA Reactome UniProtKB {GO:0006665=Reactome:REACT_19323, GO:0006687=Reactome:REACT_116105, GO:0005509=PMID:12888274, GO:0005788=Reactome:REACT_121176, GO:0004065=PMID:2562955, GO:0044281=Reactome:REACT_111217, GO:0004098=Reactome:REACT_115556, GO:0008484=PMID:15962010, GO:0044267=Reactome:REACT_17015, GO:0005764=PMID:2562955, GO:0043687=Reactome:REACT_22161, GO:0043202=Reactome:REACT_121176} P15289 Arylsulfatase A protein 20110928 {GO:0006665=TAS, GO:0006687=TAS, GO:0005509=IDA, GO:0005788=TAS, GO:0004065=TAS, GO:0044281=TAS, GO:0004098=TAS, GO:0008484=IDA, GO:0044267=TAS, GO:0005764=TAS, GO:0043687=TAS, GO:0043202=TAS} cellular protein metabolic process, glycosphingolipid metabolic process, post-translational protein modification, small molecule metabolic process, sphingolipid metabolic process endoplasmic reticulum lumen, lysosomal lumen, lysosome arylsulfatase activity, calcium ion binding, cerebroside-sulfatase activity, sulfuric ester hydrolase activity Human ARSB Reactome UniProtKB {GO:0043627=GO_REF:0000019, GO:0044281=Reactome:REACT_111217, GO:0005764=PMID:2303452, GO:0046872=GO_REF:0000037, GO:0005739=GO_REF:0000019, GO:0030207=Reactome:REACT_120888, GO:0003943=Reactome:REACT_121276, GO:0004065=GO_REF:0000019, GO:0030204=Reactome:REACT_121206, GO:0030203=Reactome:REACT_121315, GO:0009268=GO_REF:0000019, GO:0043202=Reactome:REACT_121276, GO:0005791=GO_REF:0000019, GO:0006665=Reactome:REACT_19323, GO:0005794=GO_REF:0000019, GO:0006687=Reactome:REACT_116105, GO:0007584=GO_REF:0000019, GO:0005975=Reactome:REACT_474, GO:0006914=GO_REF:0000019, GO:0007417=GO_REF:0000019, GO:0051597=GO_REF:0000019, GO:0005788=Reactome:REACT_121125, GO:0007041=PMID:2303452, GO:0007040=PMID:1718978, GO:0044267=Reactome:REACT_17015, GO:0043687=Reactome:REACT_22161} P15848 Arylsulfatase B protein 20110928 {GO:0043627=IEA, GO:0044281=TAS, GO:0005764=TAS, GO:0046872=IEA, GO:0005739=IEA, GO:0030207=TAS, GO:0003943=TAS, GO:0004065=IEA, GO:0030204=TAS, GO:0030203=TAS, GO:0009268=IEA, GO:0043202=TAS, GO:0005791=IEA, GO:0006665=TAS, GO:0005794=IEA, GO:0006687=TAS, GO:0007584=IEA, GO:0005975=TAS, GO:0006914=IEA, GO:0007417=IEA, GO:0051597=IEA, GO:0005788=TAS, GO:0007041=TAS, GO:0007040=TAS, GO:0044267=TAS, GO:0043687=TAS} autophagy, carbohydrate metabolic process, cellular protein metabolic process, central nervous system development, chondroitin sulfate catabolic process, chondroitin sulfate metabolic process, glycosaminoglycan metabolic process, glycosphingolipid metabolic process, lysosomal transport, lysosome organization, post-translational protein modification, response to estrogen stimulus, response to methylmercury, response to nutrient, response to pH, small molecule metabolic process, sphingolipid metabolic process Golgi apparatus, endoplasmic reticulum lumen, lysosomal lumen, lysosome, mitochondrion, rough endoplasmic reticulum N-acetylgalactosamine-4-sulfatase activity, arylsulfatase activity, metal ion binding Human ARSE Reactome UniProtKB {GO:0006665=Reactome:REACT_19323, GO:0001501=PMID:7720070, GO:0006687=Reactome:REACT_116105, GO:0005795=GO_REF:0000039, GO:0005788=Reactome:REACT_121125, GO:0004065=PMID:9192838, GO:0044281=Reactome:REACT_111217, GO:0008484=GO_REF:0000002, GO:0044267=Reactome:REACT_17015, GO:0046872=GO_REF:0000037, GO:0043687=Reactome:REACT_22161} P51690 Arylsulfatase E protein 20130301 {GO:0006665=TAS, GO:0001501=TAS, GO:0006687=TAS, GO:0005795=IEA, GO:0005788=TAS, GO:0004065=TAS, GO:0044281=TAS, GO:0008484=IEA, GO:0044267=TAS, GO:0046872=IEA, GO:0043687=TAS} cellular protein metabolic process, glycosphingolipid metabolic process, post-translational protein modification, skeletal system development, small molecule metabolic process, sphingolipid metabolic process Golgi stack, endoplasmic reticulum lumen arylsulfatase activity, metal ion binding, sulfuric ester hydrolase activity Human ARSF Reactome UniProtKB {GO:0006665=Reactome:REACT_19323, GO:0006687=Reactome:REACT_116105, GO:0005788=Reactome:REACT_121125, GO:0004065=PMID:9192838, GO:0005576=GO_REF:0000039, GO:0044281=Reactome:REACT_111217, GO:0044267=Reactome:REACT_17015, GO:0046872=GO_REF:0000037, GO:0043687=Reactome:REACT_22161} P54793 Arylsulfatase F protein 20130301 {GO:0006665=TAS, GO:0006687=TAS, GO:0005788=TAS, GO:0004065=TAS, GO:0005576=IEA, GO:0044281=TAS, GO:0044267=TAS, GO:0046872=IEA, GO:0043687=TAS} cellular protein metabolic process, glycosphingolipid metabolic process, post-translational protein modification, small molecule metabolic process, sphingolipid metabolic process endoplasmic reticulum lumen, extracellular region arylsulfatase activity, metal ion binding Human ART1 Reactome UniProtKB {GO:0006471=GO_REF:0000002, GO:0005886=Reactome:REACT_115620, GO:0009986=GO_REF:0000019, GO:0005887=PMID:7947688, GO:0045087=Reactome:REACT_6802, GO:0003956=GO_REF:0000003, GO:0033017=GO_REF:0000039, GO:0031225=GO_REF:0000037, GO:0003950=GO_REF:0000019} P52961 GPI-linked NAD(P)(+)--arginine ADP-ribosyltransferase 1 protein 20130301 {GO:0006471=IEA, GO:0005886=TAS, GO:0009986=IEA, GO:0005887=TAS, GO:0045087=TAS, GO:0003956=IEA, GO:0033017=IEA, GO:0031225=IEA, GO:0003950=IEA} innate immune response, protein ADP-ribosylation anchored to membrane, cell surface, integral to plasma membrane, plasma membrane, sarcoplasmic reticulum membrane NAD(P)+-protein-arginine ADP-ribosyltransferase activity, NAD+ ADP-ribosyltransferase activity Human ART3 InterPro UniProtKB {GO:0006471=GO_REF:0000002, GO:0005887=PMID:9119374, GO:0003956=GO_REF:0000002, GO:0031225=GO_REF:0000037, GO:0003950=PMID:9119374} Q5J1K9 Mono-ADP-ribosyltransferase 3 variant Ia protein 20130413 {GO:0006471=IEA, GO:0005887=TAS, GO:0003956=IEA, GO:0031225=IEA, GO:0003950=TAS} protein ADP-ribosylation anchored to membrane, integral to plasma membrane NAD(P)+-protein-arginine ADP-ribosyltransferase activity, NAD+ ADP-ribosyltransferase activity Human InterPro:IPR000768 ART4 UniProtKB UniProtKB {GO:0006471=PMID:9119374, GO:0016020=PMID:9119374, GO:0005886=GO_REF:0000039, GO:0003956=PMID:9119374, GO:0006525=PMID:11001920, GO:0031225=GO_REF:0000037} Q93070 Ecto-ADP-ribosyltransferase 4 protein 20010921 {GO:0006471=NAS, GO:0016020=NAS, GO:0005886=IEA, GO:0003956=NAS, GO:0006525=NAS, GO:0031225=IEA} arginine metabolic process, protein ADP-ribosylation anchored to membrane, membrane, plasma membrane NAD(P)+-protein-arginine ADP-ribosyltransferase activity Human ARTN Reactome UniProtKB {GO:0050930=GO_REF:0000019, GO:0007165=PMID:9883723, GO:0061146=GO_REF:0000019, GO:0097021=GO_REF:0000019, GO:0007411=Reactome:REACT_18266, GO:0007422=GO_REF:0000019, GO:0005102=PMID:9883723, GO:0008083=GO_REF:0000037, GO:0005615=GO_REF:0000019, GO:0007405=PMID:9883723} Q5T4W7 Artemin protein 20130301 {GO:0050930=IEA, GO:0007165=TAS, GO:0061146=IEA, GO:0097021=IEA, GO:0007411=TAS, GO:0007422=IEA, GO:0005102=TAS, GO:0008083=IEA, GO:0005615=IEA, GO:0007405=TAS} Peyer's patch morphogenesis, axon guidance, induction of positive chemotaxis, lymphocyte migration into lymphoid organs, neuroblast proliferation, peripheral nervous system development, signal transduction extracellular space growth factor activity, receptor binding Human ARV1 ENSEMBL UniProtKB {GO:0006665=GO_REF:0000037, GO:0090181=GO_REF:0000019, GO:0008206=GO_REF:0000019, GO:0030301=GO_REF:0000019, GO:0016021=GO_REF:0000037} Q9H2C2 Protein ARV1 protein 20130413 {GO:0006665=IEA, GO:0090181=IEA, GO:0008206=IEA, GO:0030301=IEA, GO:0016021=IEA} bile acid metabolic process, cholesterol transport, regulation of cholesterol metabolic process, sphingolipid metabolic process integral to membrane Human Ensembl:ENSMUSP00000034463 ARVCF PINC UniProtKB {GO:0005622=PMID:9126485, GO:0005515=PMID:19706687, GO:0005737=GO_REF:0000019, GO:0005886=GO_REF:0000019, GO:0007275=PMID:9126485, GO:0005634=GO_REF:0000019, GO:0007155=GO_REF:0000037} O00192 Armadillo repeat protein deleted in velo-cardio-facial syndrome protein 20030904 {GO:0005622=TAS, GO:0005515=IPI, GO:0005737=IEA, GO:0005886=IEA, GO:0007275=TAS, GO:0005634=IEA, GO:0007155=IEA} cell adhesion, multicellular organismal development cytoplasm, intracellular, nucleus, plasma membrane protein binding Human AS3MT UniProtKB UniProtKB {GO:0030791=GO_REF:0000024, GO:0005739=GO_REF:0000019, GO:0030792=GO_REF:0000024, GO:0009404=GO_REF:0000024, GO:0018872=GO_REF:0000024, GO:0005829=GO_REF:0000024} Q9HBK9 Arsenite methyltransferase protein 20041006 {GO:0030791=ISS, GO:0005739=IEA, GO:0030792=ISS, GO:0009404=ISS, GO:0018872=ISS, GO:0005829=ISS} arsonoacetate metabolic process, toxin metabolic process cytosol, mitochondrion arsenite methyltransferase activity, methylarsonite methyltransferase activity Human UniProtKB:Q8VHT6 ASAH1 Reactome UniProtKB {GO:0006629=GO_REF:0000002, GO:0006665=Reactome:REACT_19323, GO:0008219=GO_REF:0000037, GO:0010033=GO_REF:0000019, GO:0006687=Reactome:REACT_116105, GO:0030324=GO_REF:0000019, GO:0006672=PMID:8955159, GO:0044281=Reactome:REACT_111217, GO:0003824=PMID:8955159, GO:0005764=GO_REF:0000002, GO:0017040=Reactome:REACT_115911, GO:0016787=GO_REF:0000002, GO:0043202=Reactome:REACT_115911} Q13510 Acid ceramidase protein 20110923 {GO:0006629=IEA, GO:0006665=TAS, GO:0008219=IEA, GO:0010033=IEA, GO:0006687=TAS, GO:0030324=IEA, GO:0006672=TAS, GO:0044281=TAS, GO:0003824=TAS, GO:0005764=IEA, GO:0017040=TAS, GO:0016787=IEA, GO:0043202=TAS} cell death, ceramide metabolic process, glycosphingolipid metabolic process, lipid metabolic process, lung development, response to organic substance, small molecule metabolic process, sphingolipid metabolic process lysosomal lumen, lysosome catalytic activity, ceramidase activity, hydrolase activity Human ASAH2 Reactome UniProtKB {GO:0006665=Reactome:REACT_19323, GO:0005739=PMID:10781606, GO:0007165=PMID:10781606, GO:0017040=GO_REF:0000003, GO:0006687=Reactome:REACT_116105, GO:0005886=Reactome:REACT_115894, GO:0006672=PMID:10781606, GO:0006915=GO_REF:0000037, GO:0044281=Reactome:REACT_111217, GO:0016021=GO_REF:0000037} Q9NR71 Neutral ceramidase protein 20130301 {GO:0006665=TAS, GO:0005739=TAS, GO:0007165=TAS, GO:0017040=IEA, GO:0006687=TAS, GO:0005886=TAS, GO:0006672=TAS, GO:0006915=IEA, GO:0044281=TAS, GO:0016021=IEA} apoptotic process, ceramide metabolic process, glycosphingolipid metabolic process, signal transduction, small molecule metabolic process, sphingolipid metabolic process integral to membrane, mitochondrion, plasma membrane ceramidase activity Human ASAH2B null null {} null null null null {} null null null ASAP1 IntAct UniProtKB {GO:0005515=PMID:21988832, GO:0008060=GO_REF:0000002, GO:0005737=GO_REF:0000039, GO:0005543=GO_REF:0000002, GO:0016020=GO_REF:0000039, GO:0032312=GO_REF:0000002, GO:0060271=PMID:20393563, GO:0008270=GO_REF:0000002} Q9ULH1 Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1 protein 20130415 {GO:0005515=IPI, GO:0008060=IEA, GO:0005737=IEA, GO:0005543=IEA, GO:0016020=IEA, GO:0032312=IEA, GO:0060271=IMP, GO:0008270=IEA} cilium morphogenesis, regulation of ARF GTPase activity cytoplasm, membrane ARF GTPase activator activity, phospholipid binding, protein binding, zinc ion binding Human UniProtKB:P62993 ASAP2 GOC UniProtKB {GO:0005515=PMID:21706016, GO:0008060=GO_REF:0000002, GO:0005543=GO_REF:0000002, GO:0005886=GO_REF:0000039, GO:0032312=GO_REF:0000002, GO:0032580=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0043085=PMID:9819391, GO:0008047=PMID:9819391} O43150 Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 2 protein 20130413 {GO:0005515=IPI, GO:0008060=IEA, GO:0005543=IEA, GO:0005886=IEA, GO:0032312=IEA, GO:0032580=IEA, GO:0008270=IEA, GO:0043085=TAS, GO:0008047=TAS} positive regulation of catalytic activity, regulation of ARF GTPase activity Golgi cisterna membrane, plasma membrane ARF GTPase activator activity, enzyme activator activity, phospholipid binding, protein binding, zinc ion binding Human ASAP3 UniProtKB UniProtKB {GO:0008060=GO_REF:0000002, GO:0005737=GO_REF:0000039, GO:0005543=GO_REF:0000002, GO:0032312=GO_REF:0000002, GO:0008270=GO_REF:0000002} Q8TDY4 Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 3 protein 20130413 {GO:0008060=IEA, GO:0005737=IEA, GO:0005543=IEA, GO:0032312=IEA, GO:0008270=IEA} regulation of ARF GTPase activity cytoplasm ARF GTPase activator activity, phospholipid binding, zinc ion binding Human UniProtKB-SubCell:SL-0086 ASB1 UniProtKB UniProtKB {GO:0005622=PMID:11111040, GO:0042036=PMID:11111040, GO:0035556=GO_REF:0000002, GO:0003674=GO_REF:0000015, GO:0030539=GO_REF:0000019, GO:0016567=GO_REF:0000041} Q9Y576 Ankyrin repeat and SOCS box protein 1 protein 20040225 {GO:0005622=IC, GO:0042036=NAS, GO:0035556=IEA, GO:0003674=ND, GO:0030539=IEA, GO:0016567=IEA} intracellular signal transduction, male genitalia development, negative regulation of cytokine biosynthetic process, protein ubiquitination intracellular molecular_function Human GO:0042036 ASB10 UniPathway UniProtKB {GO:0035556=GO_REF:0000002, GO:0016567=GO_REF:0000041} Q8WXI3 Ankyrin repeat and SOCS box protein 10 protein 20130413 {GO:0035556=IEA, GO:0016567=IEA} intracellular signal transduction, protein ubiquitination Human UniPathway:UPA00143 ASB12 UniPathway UniProtKB {GO:0035556=GO_REF:0000002, GO:0016567=GO_REF:0000041} Q8WXK4 Ankyrin repeat and SOCS box protein 12 protein 20130413 {GO:0035556=IEA, GO:0016567=IEA} intracellular signal transduction, protein ubiquitination Human UniPathway:UPA00143 ASB13 IntAct UniProtKB {GO:0005515=PMID:16169070, GO:0035556=GO_REF:0000002, GO:0016567=GO_REF:0000041} Q8WXK3 Ankyrin repeat and SOCS box protein 13 protein 20130415 {GO:0005515=IPI, GO:0035556=IEA, GO:0016567=IEA} intracellular signal transduction, protein ubiquitination protein binding Human UniProtKB:P27448 ASB16 IntAct UniProtKB {GO:0005515=PMID:17474147, GO:0035556=GO_REF:0000002, GO:0016567=GO_REF:0000041} Q96NS5 Ankyrin repeat and SOCS box protein 16 protein 20130415 {GO:0005515=IPI, GO:0035556=IEA, GO:0016567=IEA} intracellular signal transduction, protein ubiquitination protein binding Human UniProtKB:P16333 ASB17 UniPathway UniProtKB {GO:0035556=GO_REF:0000002, GO:0016567=GO_REF:0000041} Q8WXJ9 Ankyrin repeat and SOCS box protein 17 protein 20130413 {GO:0035556=IEA, GO:0016567=IEA} intracellular signal transduction, protein ubiquitination Human UniPathway:UPA00143 ASB2 PINC UniProtKB {GO:0035556=GO_REF:0000002, GO:0007165=PMID:9419338, GO:0016567=GO_REF:0000041} Q96Q27 Ankyrin repeat and SOCS box protein 2 protein 20050308 {GO:0035556=IEA, GO:0007165=TAS, GO:0016567=IEA} intracellular signal transduction, protein ubiquitination, signal transduction Human ASB3 UniPathway UniProtKB {GO:0035556=GO_REF:0000002, GO:0016567=GO_REF:0000041} Q9Y575 Ankyrin repeat and SOCS box protein 3 protein 20130413 {GO:0035556=IEA, GO:0016567=IEA} intracellular signal transduction, protein ubiquitination Human UniPathway:UPA00143 ASB4 UniProtKB UniProtKB {GO:0035556=GO_REF:0000002, GO:0004842=GO_REF:0000019, GO:2001214=GO_REF:0000024, GO:0031462=PMID:17636018, GO:0031466=PMID:17636018, GO:0031625=GO_REF:0000019, GO:0051865=GO_REF:0000019} Q9Y574 Ankyrin repeat and SOCS box protein 4 protein 20120313 {GO:0035556=IEA, GO:0004842=IEA, GO:2001214=ISS, GO:0031462=IDA, GO:0031466=IDA, GO:0031625=IEA, GO:0051865=IEA} intracellular signal transduction, positive regulation of vasculogenesis, protein autoubiquitination Cul2-RING ubiquitin ligase complex, Cul5-RING ubiquitin ligase complex ubiquitin protein ligase binding, ubiquitin-protein ligase activity Human UniProtKB:Q9WV71 ASB6 UniPathway UniProtKB {GO:0035556=GO_REF:0000002, GO:0005737=GO_REF:0000039, GO:0016567=GO_REF:0000041} Q9NWX5 Ankyrin repeat and SOCS box protein 6 protein 20130413 {GO:0035556=IEA, GO:0005737=IEA, GO:0016567=IEA} intracellular signal transduction, protein ubiquitination cytoplasm Human UniPathway:UPA00143 ASB7 UniPathway UniProtKB {GO:0035556=GO_REF:0000002, GO:0016567=GO_REF:0000041} Q9H672 Ankyrin repeat and SOCS box protein 7 protein 20130413 {GO:0035556=IEA, GO:0016567=IEA} intracellular signal transduction, protein ubiquitination Human UniPathway:UPA00143 ASB8 HPA UniProtKB {GO:0035556=GO_REF:0000002, GO:0005737=GO_REF:0000052, GO:0016567=GO_REF:0000041, GO:0005634=GO_REF:0000052} Q9H765 Ankyrin repeat and SOCS box protein 8 protein 20080205 {GO:0035556=IEA, GO:0005737=IDA, GO:0016567=IEA, GO:0005634=IDA} intracellular signal transduction, protein ubiquitination cytoplasm, nucleus Human ASB9 HPA UniProtKB {GO:0005515=PMID:19060904, GO:0005739=GO_REF:0000039, GO:0035556=GO_REF:0000002, GO:0005737=GO_REF:0000052, GO:0045732=PMID:17148442, GO:0016567=PMID:17148442, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052} Q96DX5 Ankyrin repeat and SOCS box protein 9 protein 20101115 {GO:0005515=IPI, GO:0005739=IEA, GO:0035556=IEA, GO:0005737=IDA, GO:0045732=IDA, GO:0016567=IDA, GO:0005730=IDA, GO:0005634=IDA} intracellular signal transduction, positive regulation of protein catabolic process, protein ubiquitination cytoplasm, mitochondrion, nucleolus, nucleus protein binding Human ASCC1 MGI UniProtKB {GO:0005667=PMID:12077347, GO:0006355=PMID:12077347, GO:0005737=GO_REF:0000039, GO:0016070=GO_REF:0000002, GO:0003723=GO_REF:0000002, GO:0003824=GO_REF:0000002, GO:0006351=GO_REF:0000037} Q8N9N2 Activating signal cointegrator 1 complex subunit 1 protein 20091020 {GO:0005667=IDA, GO:0006355=IDA, GO:0005737=IEA, GO:0016070=IEA, GO:0003723=IEA, GO:0003824=IEA, GO:0006351=IEA} RNA metabolic process, regulation of transcription, DNA-dependent, transcription, DNA-dependent cytoplasm, transcription factor complex RNA binding, catalytic activity Human ASCC2 UniProtKB UniProtKB {GO:0006355=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q9H1I8 Activating signal cointegrator 1 complex subunit 2 protein 20130413 {GO:0006355=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent Human UniProtKB-KW:KW-0805 ASCC3 LIFEdb UniProtKB {GO:0005515=PMID:22055184, GO:0006355=GO_REF:0000037, GO:0043140=PMID:22055184, GO:0005794=GO_REF:0000052, GO:0008283=PMID:22055184, GO:0005634=PMID:22055184, GO:0003676=GO_REF:0000002, GO:0005524=GO_REF:0000037, GO:0006351=GO_REF:0000037, GO:0005622=GO_REF:0000054, GO:0005737=GO_REF:0000039, GO:0006307=PMID:22055184, GO:0032508=PMID:22055184} Q8N3C0 Activating signal cointegrator 1 complex subunit 3 protein 20100607 {GO:0005515=IPI, GO:0006355=IEA, GO:0043140=IDA, GO:0005794=IDA, GO:0008283=IMP, GO:0005634=TAS, GO:0003676=IEA, GO:0005524=IEA, GO:0006351=IEA, GO:0005622=IDA, GO:0005737=IEA, GO:0006307=IDA, GO:0032508=IDA} DNA dealkylation involved in DNA repair, DNA duplex unwinding, cell proliferation, regulation of transcription, DNA-dependent, transcription, DNA-dependent Golgi apparatus, cytoplasm, intracellular, nucleus ATP binding, ATP-dependent 3'-5' DNA helicase activity, nucleic acid binding, protein binding Human ASCL1 IntAct UniProtKB {GO:0005515=PMID:10903890, GO:0007389=GO_REF:0000019, GO:0003700=PMID:10903890, GO:0061104=GO_REF:0000019, GO:0061103=GO_REF:0000019, GO:0061102=GO_REF:0000019, GO:0061100=GO_REF:0000019, GO:0042803=GO_REF:0000019, GO:0000989=GO_REF:0000024, GO:0007405=GO_REF:0000019, GO:0071259=GO_REF:0000019, GO:0003690=GO_REF:0000019, GO:0043525=GO_REF:0000019, GO:0007219=PMID:16160079, GO:0043025=GO_REF:0000019, GO:0021892=PMID:12050665, GO:0045747=GO_REF:0000019, GO:2000179=GO_REF:0000019, GO:0021879=GO_REF:0000019, GO:0070888=PMID:11736660, GO:0045787=GO_REF:0000019, GO:0048485=PMID:10903890, GO:0070849=GO_REF:0000019, GO:0051593=GO_REF:0000019, GO:0060487=PMID:12858003, GO:0003359=PMID:14532329, GO:0021987=GO_REF:0000019, GO:0021530=GO_REF:0000019, GO:0005634=PMID:18311112, GO:0050769=GO_REF:0000019, GO:0045944=PMID:10903890, GO:0060166=GO_REF:0000019, GO:0060165=GO_REF:0000019, GO:0032526=PMID:12000752, GO:0060163=GO_REF:0000019, GO:0022008=PMID:19008346, GO:0043066=PMID:17507989, GO:0021954=GO_REF:0000019, GO:0048665=GO_REF:0000019, GO:0043425=PMID:10903890, GO:0003677=GO_REF:0000024, GO:0006351=GO_REF:0000037, GO:0021527=GO_REF:0000019, GO:0043565=GO_REF:0000019, GO:0010226=GO_REF:0000019, GO:0007400=GO_REF:0000019, GO:0045665=PMID:12000752, GO:0045666=GO_REF:0000024, GO:0014003=GO_REF:0000019, GO:0021750=GO_REF:0000019, GO:0001764=GO_REF:0000019} P50553 Achaete-scute homolog 1 protein 20130415 {GO:0005515=IPI, GO:0007389=IEA, GO:0003700=IDA, GO:0061104=IEA, GO:0061103=IEA, GO:0061102=IEA, GO:0061100=IEA, GO:0042803=IEA, GO:0000989=ISS, GO:0007405=IEA, GO:0071259=IEA, GO:0003690=IEA, GO:0043525=IEA, GO:0007219=IDA, GO:0043025=IEA, GO:0021892=IEP, GO:0045747=IEA, GO:2000179=IEA, GO:0021879=IEA, GO:0070888=IDA, GO:0045787=IEA, GO:0048485=NAS, GO:0070849=IEA, GO:0051593=IEA, GO:0060487=NAS, GO:0003359=IMP, GO:0021987=IEA, GO:0021530=IEA, GO:0005634=IDA, GO:0050769=IEA, GO:0045944=IDA, GO:0060166=IEA, GO:0060165=IEA, GO:0032526=IEP, GO:0060163=IEA, GO:0022008=IDA, GO:0043066=IMP, GO:0021954=IEA, GO:0048665=IEA, GO:0043425=IPI, GO:0003677=ISS, GO:0006351=IEA, GO:0021527=IEA, GO:0043565=IEA, GO:0010226=IEA, GO:0007400=IEA, GO:0045665=IDA, GO:0045666=ISS, GO:0014003=IEA, GO:0021750=IEA, GO:0001764=IEA} Notch signaling pathway, adrenal chromaffin cell differentiation, carotid body glomus cell differentiation, cellular response to magnetism, central nervous system neuron development, cerebral cortex GABAergic interneuron differentiation, cerebral cortex development, forebrain neuron differentiation, lung epithelial cell differentiation, lung neuroendocrine cell differentiation, negative regulation of apoptotic process, negative regulation of neuron differentiation, neuroblast fate determination, neuroblast proliferation, neurogenesis, neuron fate specification, neuron migration, noradrenergic neuron fate commitment, olfactory pit development, oligodendrocyte development, pattern specification process, positive regulation of Notch signaling pathway, positive regulation of cell cycle, positive regulation of neural precursor cell proliferation, positive regulation of neurogenesis, positive regulation of neuron apoptotic process, positive regulation of neuron differentiation, positive regulation of transcription from RNA polymerase II promoter, regulation of timing of subpallium neuron differentiation, response to epidermal growth factor stimulus, response to folic acid, response to lithium ion, response to retinoic acid, spinal cord association neuron differentiation, spinal cord oligodendrocyte cell fate specification, stomach neuroendocrine cell differentiation, subpallium neuron fate commitment, sympathetic nervous system development, transcription, DNA-dependent, vestibular nucleus development neuronal cell body, nucleus DNA binding, E-box binding, bHLH transcription factor binding, double-stranded DNA binding, protein binding, protein homodimerization activity, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, transcription factor binding transcription factor activity Human UniProtKB:P15923 ASCL2 UniProtKB UniProtKB {GO:0001666=PMID:14561729, GO:0006355=PMID:8751384, GO:0003700=PMID:8751384, GO:0060712=PMID:12917334, GO:0060708=GO_REF:0000019, GO:0070888=PMID:14561729, GO:0005634=PMID:11440538, GO:0000122=PMID:14561729, GO:0001890=PMID:14561729, GO:0007417=GO_REF:0000029, GO:0006351=PMID:14561729, GO:0043565=GO_REF:0000019, GO:0010626=GO_REF:0000019, GO:0007422=GO_REF:0000029, GO:0046983=GO_REF:0000002, GO:0035019=GO_REF:0000019} Q99929 Achaete-scute homolog 2 protein 20011002 {GO:0001666=IEP, GO:0006355=NAS, GO:0003700=NAS, GO:0060712=IEP, GO:0060708=IEA, GO:0070888=IDA, GO:0005634=IDA, GO:0000122=IDA, GO:0001890=NAS, GO:0007417=NAS, GO:0006351=IDA, GO:0043565=IEA, GO:0010626=IEA, GO:0007422=NAS, GO:0046983=IEA, GO:0035019=IEA} central nervous system development, negative regulation of Schwann cell proliferation, negative regulation of transcription from RNA polymerase II promoter, peripheral nervous system development, placenta development, regulation of transcription, DNA-dependent, response to hypoxia, somatic stem cell maintenance, spongiotrophoblast differentiation, spongiotrophoblast layer development, transcription, DNA-dependent nucleus E-box binding, protein dimerization activity, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity Human ASCL3 HPA UniProtKB {GO:0005667=GO_REF:0000019, GO:0006357=GO_REF:0000024, GO:0005730=GO_REF:0000052, GO:0046983=GO_REF:0000002, GO:0005634=GO_REF:0000052, GO:0003677=GO_REF:0000024, GO:0006351=GO_REF:0000024, GO:0043231=GO_REF:0000052} Q9NQ33 Achaete-scute homolog 3 protein 20101115 {GO:0005667=IEA, GO:0006357=ISS, GO:0005730=IDA, GO:0046983=IEA, GO:0005634=IDA, GO:0003677=ISS, GO:0006351=ISS, GO:0043231=IDA} regulation of transcription from RNA polymerase II promoter, transcription, DNA-dependent intracellular membrane-bounded organelle, nucleolus, nucleus, transcription factor complex DNA binding, protein dimerization activity Human ASCL4 UniProtKB UniProtKB {GO:0006357=PMID:15475265, GO:0046983=GO_REF:0000002, GO:0043588=PMID:15475265, GO:0005634=GO_REF:0000039, GO:0005575=GO_REF:0000015, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q6XD76 Achaete-scute homolog 4 protein 20110107 {GO:0006357=NAS, GO:0046983=IEA, GO:0043588=NAS, GO:0005634=IEA, GO:0005575=ND, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription from RNA polymerase II promoter, skin development, transcription, DNA-dependent cellular_component, nucleus DNA binding, protein dimerization activity Human ASF1A IntAct UniProtKB {GO:0005515=PMID:21217774, GO:0042692=GO_REF:0000019, GO:0042393=PMID:10759893, GO:0006281=PMID:11897662, GO:0003682=PMID:10759893, GO:0006334=PMID:11897662, GO:0005634=GO_REF:0000054, GO:0001649=GO_REF:0000019, GO:0006351=GO_REF:0000037, GO:0031936=PMID:10759893, GO:0016568=GO_REF:0000037} Q9Y294 Histone chaperone ASF1A protein 20130415 {GO:0005515=IPI, GO:0042692=IEA, GO:0042393=IDA, GO:0006281=IDA, GO:0003682=NAS, GO:0006334=IDA, GO:0005634=IDA, GO:0001649=IEA, GO:0006351=IEA, GO:0031936=NAS, GO:0016568=IEA} DNA repair, chromatin modification, muscle cell differentiation, negative regulation of chromatin silencing, nucleosome assembly, osteoblast differentiation, transcription, DNA-dependent nucleus chromatin binding, histone binding, protein binding Human UniProtKB:P03372 ASF1B UniProtKB UniProtKB {GO:0005515=PMID:22407294, GO:0042393=GO_REF:0000019, GO:0006355=GO_REF:0000037, GO:0006334=GO_REF:0000019, GO:0007275=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0007283=GO_REF:0000037, GO:0000785=GO_REF:0000019, GO:0030154=GO_REF:0000037, GO:0006351=GO_REF:0000037, GO:0016568=GO_REF:0000037, GO:0006333=GO_REF:0000002} Q9NVP2 Histone chaperone ASF1B protein 20121123 {GO:0005515=IPI, GO:0042393=IEA, GO:0006355=IEA, GO:0006334=IEA, GO:0007275=IEA, GO:0005634=IEA, GO:0007283=IEA, GO:0000785=IEA, GO:0030154=IEA, GO:0006351=IEA, GO:0016568=IEA, GO:0006333=IEA} cell differentiation, chromatin assembly or disassembly, chromatin modification, multicellular organismal development, nucleosome assembly, regulation of transcription, DNA-dependent, spermatogenesis, transcription, DNA-dependent chromatin, nucleus histone binding, protein binding Human UniProtKB:Q8IWY9 ASGR1 IntAct UniProtKB {GO:0005515=PMID:21988832, GO:0005887=PMID:10734069, GO:0031668=GO_REF:0000019, GO:0004873=GO_REF:0000019, GO:0030246=GO_REF:0000002, GO:0005576=GO_REF:0000039, GO:0006898=PMID:8439566, GO:0046872=GO_REF:0000037, GO:0042803=GO_REF:0000019} P07306 Asialoglycoprotein receptor 1 protein 20130415 {GO:0005515=IPI, GO:0005887=TAS, GO:0031668=IEA, GO:0004873=IEA, GO:0030246=IEA, GO:0005576=IEA, GO:0006898=TAS, GO:0046872=IEA, GO:0042803=IEA} cellular response to extracellular stimulus, receptor-mediated endocytosis extracellular region, integral to plasma membrane asialoglycoprotein receptor activity, carbohydrate binding, metal ion binding, protein binding, protein homodimerization activity Human UniProtKB:Q96G23 ASGR2 IntAct UniProtKB {GO:0005515=PMID:21988832, GO:0009100=GO_REF:0000019, GO:0031647=GO_REF:0000019, GO:0055088=GO_REF:0000019, GO:0004873=PMID:3863106, GO:0030246=GO_REF:0000002, GO:0030282=GO_REF:0000019, GO:0016021=GO_REF:0000037, GO:0007166=PMID:3863106} P07307 Asialoglycoprotein receptor 2 protein 20130415 {GO:0005515=IPI, GO:0009100=IEA, GO:0031647=IEA, GO:0055088=IEA, GO:0004873=TAS, GO:0030246=IEA, GO:0030282=IEA, GO:0016021=IEA, GO:0007166=TAS} bone mineralization, cell surface receptor signaling pathway, glycoprotein metabolic process, lipid homeostasis, regulation of protein stability integral to membrane asialoglycoprotein receptor activity, carbohydrate binding, protein binding Human UniProtKB:Q96G23 ASH1L HPA UniProtKB {GO:0006355=GO_REF:0000037, GO:0005794=GO_REF:0000052, GO:0006366=PMID:10860993, GO:0005694=GO_REF:0000039, GO:0007267=PMID:10860993, GO:0005730=GO_REF:0000052, GO:0006323=PMID:10860993, GO:0005634=GO_REF:0000052, GO:0003677=GO_REF:0000002, GO:0018024=GO_REF:0000003, GO:0005737=GO_REF:0000052, GO:0008270=GO_REF:0000002, GO:0005923=GO_REF:0000039} Q9NR48 Histone-lysine N-methyltransferase ASH1L protein 20101115 {GO:0006355=IEA, GO:0005794=IDA, GO:0006366=TAS, GO:0005694=IEA, GO:0007267=TAS, GO:0005730=IDA, GO:0006323=TAS, GO:0005634=IDA, GO:0003677=IEA, GO:0018024=IEA, GO:0005737=IDA, GO:0008270=IEA, GO:0005923=IEA} DNA packaging, cell-cell signaling, regulation of transcription, DNA-dependent, transcription from RNA polymerase II promoter Golgi apparatus, chromosome, cytoplasm, nucleolus, nucleus, tight junction DNA binding, histone-lysine N-methyltransferase activity, zinc ion binding Human ASH2L IntAct UniProtKB {GO:0005515=PMID:19556245, GO:0030097=PMID:11466562, GO:0008284=PMID:18245475, GO:0006355=PMID:10393421, GO:0043627=PMID:16603732, GO:0006366=PMID:10393421, GO:0044212=PMID:16603732, GO:0005634=PMID:17500065, GO:0042800=PMID:17355966, GO:0003677=PMID:10393421, GO:0006974=PMID:17500065, GO:0046872=GO_REF:0000037, GO:0006351=PMID:10393421, GO:0035097=PMID:14992727, GO:0045944=GO_REF:0000019, GO:0048188=PMID:18838538, GO:0051568=PMID:17355966} Q9UBL3 Set1/Ash2 histone methyltransferase complex subunit ASH2 protein 20130415 {GO:0005515=IPI, GO:0030097=NAS, GO:0008284=IMP, GO:0006355=NAS, GO:0043627=IDA, GO:0006366=TAS, GO:0044212=IDA, GO:0005634=IDA, GO:0042800=IDA, GO:0003677=IC, GO:0006974=IDA, GO:0046872=IEA, GO:0006351=NAS, GO:0035097=IPI, GO:0045944=IEA, GO:0048188=IDA, GO:0051568=IDA} hemopoiesis, histone H3-K4 methylation, positive regulation of cell proliferation, positive regulation of transcription from RNA polymerase II promoter, regulation of transcription, DNA-dependent, response to DNA damage stimulus, response to estrogen stimulus, transcription from RNA polymerase II promoter, transcription, DNA-dependent Set1C/COMPASS complex, histone methyltransferase complex, nucleus DNA binding, histone methyltransferase activity (H3-K4 specific), metal ion binding, protein binding, transcription regulatory region DNA binding Human UniProtKB:Q9C005 ASIP PINC UniProtKB {GO:0008343=GO_REF:0000019, GO:0032438=GO_REF:0000019, GO:0007267=PMID:7757071, GO:0005102=PMID:7757071, GO:0006091=GO_REF:0000019, GO:0005615=PMID:7937887, GO:0032402=GO_REF:0000019, GO:0040030=GO_REF:0000019, GO:0007165=PMID:7757071, GO:0009755=GO_REF:0000002, GO:0042438=GO_REF:0000019, GO:0031781=GO_REF:0000019, GO:0071514=GO_REF:0000019, GO:0031782=GO_REF:0000019} P42127 Agouti-signaling protein protein 20030904 {GO:0008343=IEA, GO:0032438=IEA, GO:0007267=TAS, GO:0005102=TAS, GO:0006091=IEA, GO:0005615=TAS, GO:0032402=IEA, GO:0040030=IEA, GO:0007165=TAS, GO:0009755=IEA, GO:0042438=IEA, GO:0031781=IEA, GO:0071514=IEA, GO:0031782=IEA} adult feeding behavior, cell-cell signaling, generation of precursor metabolites and energy, genetic imprinting, hormone-mediated signaling pathway, melanin biosynthetic process, melanosome organization, melanosome transport, regulation of molecular function, epigenetic, signal transduction extracellular space receptor binding, type 3 melanocortin receptor binding, type 4 melanocortin receptor binding Human ASL Reactome UniProtKB {GO:0034641=Reactome:REACT_13, GO:0042450=GO_REF:0000002, GO:0005737=PMID:282632, GO:0000050=Reactome:REACT_847, GO:0044281=Reactome:REACT_111217, GO:0006527=PMID:282632, GO:0006475=PMID:20167786, GO:0004056=Reactome:REACT_1378, GO:0005829=Reactome:REACT_1378} P04424 Argininosuccinate lyase protein 20130213 {GO:0034641=TAS, GO:0042450=IEA, GO:0005737=TAS, GO:0000050=TAS, GO:0044281=TAS, GO:0006527=TAS, GO:0006475=IDA, GO:0004056=EXP, GO:0005829=TAS} arginine biosynthetic process via ornithine, arginine catabolic process, cellular nitrogen compound metabolic process, internal protein amino acid acetylation, small molecule metabolic process, urea cycle cytoplasm, cytosol argininosuccinate lyase activity Human ASMTL HPA UniProtKB {GO:0003674=GO_REF:0000015, GO:0008150=GO_REF:0000015, GO:0005737=GO_REF:0000052, GO:0008171=GO_REF:0000002} O95671 N-acetylserotonin O-methyltransferase-like protein protein 20080205 {GO:0003674=ND, GO:0008150=ND, GO:0005737=IDA, GO:0008171=IEA} biological_process cytoplasm O-methyltransferase activity, molecular_function Human ASNA1 PINC UniProtKB {GO:0005215=PMID:9736449, GO:0005737=PMID:9736449, GO:0005783=GO_REF:0000039, GO:0015105=PMID:8884272, GO:0006810=PMID:9736449, GO:0005730=GO_REF:0000039, GO:0005524=GO_REF:0000037, GO:0016887=GO_REF:0000002, GO:0046872=GO_REF:0000037} O43681 ATPase ASNA1 protein 20030904 {GO:0005215=TAS, GO:0005737=TAS, GO:0005783=IEA, GO:0015105=TAS, GO:0006810=TAS, GO:0005730=IEA, GO:0005524=IEA, GO:0016887=IEA, GO:0046872=IEA} transport cytoplasm, endoplasmic reticulum, nucleolus ATP binding, ATPase activity, arsenite transmembrane transporter activity, metal ion binding, transporter activity Human ASNS Reactome UniProtKB {GO:0070981=GO_REF:0000041, GO:0031427=GO_REF:0000019, GO:0044281=Reactome:REACT_111217, GO:0042803=GO_REF:0000019, GO:0032870=GO_REF:0000019, GO:0005829=Reactome:REACT_115759, GO:0030968=Reactome:REACT_18356, GO:0034641=Reactome:REACT_13, GO:0004066=Reactome:REACT_277, GO:0009416=GO_REF:0000019, GO:0042149=PMID:10085239, GO:0043200=GO_REF:0000019, GO:0006529=PMID:2573597, GO:0032354=GO_REF:0000019, GO:0048037=GO_REF:0000019, GO:0043066=PMID:17409444, GO:0009636=GO_REF:0000019, GO:0008652=Reactome:REACT_238, GO:0005524=GO_REF:0000037, GO:0009612=GO_REF:0000019, GO:0001889=GO_REF:0000019, GO:0045931=PMID:2569668, GO:0006987=Reactome:REACT_18277, GO:0044267=Reactome:REACT_17015, GO:0006541=GO_REF:0000037} P08243 "Asparagine synthetase ""glutamine-hydrolyzing""" protein 20130213 {GO:0070981=IEA, GO:0031427=IEA, GO:0044281=TAS, GO:0042803=IEA, GO:0032870=IEA, GO:0005829=TAS, GO:0030968=TAS, GO:0034641=TAS, GO:0004066=EXP, GO:0009416=IEA, GO:0042149=IDA, GO:0043200=IEA, GO:0006529=IDA, GO:0032354=IEA, GO:0048037=IEA, GO:0043066=IMP, GO:0009636=IEA, GO:0008652=TAS, GO:0005524=IEA, GO:0009612=IEA, GO:0001889=IEA, GO:0045931=IDA, GO:0006987=TAS, GO:0044267=TAS, GO:0006541=IEA} L-asparagine biosynthetic process, activation of signaling protein activity involved in unfolded protein response, asparagine biosynthetic process, cellular amino acid biosynthetic process, cellular nitrogen compound metabolic process, cellular protein metabolic process, cellular response to glucose starvation, cellular response to hormone stimulus, endoplasmic reticulum unfolded protein response, glutamine metabolic process, liver development, negative regulation of apoptotic process, positive regulation of mitotic cell cycle, response to amino acid stimulus, response to follicle-stimulating hormone stimulus, response to light stimulus, response to mechanical stimulus, response to methotrexate, response to toxic substance, small molecule metabolic process cytosol ATP binding, asparagine synthase (glutamine-hydrolyzing) activity, cofactor binding, protein homodimerization activity Human ASNSD1 BHF-UCL UniProtKB {GO:0008150=GO_REF:0000015, GO:0003674=GO_REF:0000015, GO:0004066=GO_REF:0000002, GO:0005575=GO_REF:0000015, GO:0006529=GO_REF:0000037, GO:0006541=GO_REF:0000037} Q9NWL6 Asparagine synthetase domain-containing protein 1 protein 20120601 {GO:0008150=ND, GO:0003674=ND, GO:0004066=IEA, GO:0005575=ND, GO:0006529=IEA, GO:0006541=IEA} asparagine biosynthetic process, biological_process, glutamine metabolic process cellular_component asparagine synthase (glutamine-hydrolyzing) activity, molecular_function Human ASPA HPA UniProtKB {GO:0005737=GO_REF:0000052, GO:0019807=GO_REF:0000003, GO:0006533=PMID:8252036, GO:0022010=GO_REF:0000019, GO:0048714=GO_REF:0000019, GO:0016788=GO_REF:0000002, GO:0005634=GO_REF:0000039, GO:0004046=PMID:8252036, GO:0046872=GO_REF:0000037} P45381 Aspartoacylase protein 20100326 {GO:0005737=IDA, GO:0019807=IEA, GO:0006533=TAS, GO:0022010=IEA, GO:0048714=IEA, GO:0016788=IEA, GO:0005634=IEA, GO:0004046=TAS, GO:0046872=IEA} aspartate catabolic process, central nervous system myelination, positive regulation of oligodendrocyte differentiation cytoplasm, nucleus aminoacylase activity, aspartoacylase activity, hydrolase activity, acting on ester bonds, metal ion binding Human ASPH BHF-UCL UniProtKB {GO:0005515=PMID:22586105, GO:0032541=PMID:21062895, GO:0007389=GO_REF:0000019, GO:0008285=GO_REF:0000019, GO:0005886=PMID:21062895, GO:0005783=PMID:11007777, GO:0042264=GO_REF:0000019, GO:0005509=PMID:11007777, GO:0004597=GO_REF:0000003, GO:0009055=PMID:7821814, GO:0097202=PMID:18387192, GO:0045862=PMID:18387192, GO:0008150=GO_REF:0000015, GO:0006936=PMID:10974562, GO:0016020=GO_REF:0000002, GO:0060325=GO_REF:0000019, GO:0005198=PMID:11007777, GO:0018193=GO_REF:0000002, GO:0005789=PMID:11007777, GO:0060021=GO_REF:0000019, GO:0016021=GO_REF:0000037, GO:0008307=PMID:11007777, GO:0016702=GO_REF:0000037, GO:0035108=GO_REF:0000019} Q12797 Aspartyl/asparaginyl beta-hydroxylase protein 20130219 {GO:0005515=IPI, GO:0032541=IDA, GO:0007389=IEA, GO:0008285=IEA, GO:0005886=IDA, GO:0005783=TAS, GO:0042264=IEA, GO:0005509=NAS, GO:0004597=IEA, GO:0009055=TAS, GO:0097202=IDA, GO:0045862=IDA, GO:0008150=ND, GO:0006936=TAS, GO:0016020=IEA, GO:0060325=IEA, GO:0005198=TAS, GO:0018193=IEA, GO:0005789=NAS, GO:0060021=IEA, GO:0016021=IEA, GO:0008307=TAS, GO:0016702=IEA, GO:0035108=IEA} activation of cysteine-type endopeptidase activity, biological_process, face morphogenesis, limb morphogenesis, muscle contraction, negative regulation of cell proliferation, palate development, pattern specification process, peptidyl-amino acid modification, peptidyl-aspartic acid hydroxylation, positive regulation of proteolysis cortical endoplasmic reticulum, endoplasmic reticulum, endoplasmic reticulum membrane, integral to membrane, membrane, plasma membrane calcium ion binding, electron carrier activity, oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen, peptide-aspartate beta-dioxygenase activity, protein binding, structural constituent of muscle, structural molecule activity Human ASPM UniProtKB UniProtKB {GO:0005516=GO_REF:0000037, GO:0048477=GO_REF:0000019, GO:0090263=GO_REF:0000019, GO:0002052=GO_REF:0000019, GO:0030496=GO_REF:0000019, GO:0005634=GO_REF:0000039, GO:0007283=GO_REF:0000019, GO:0021873=GO_REF:0000019, GO:0045769=GO_REF:0000019, GO:0005737=GO_REF:0000039, GO:0007067=GO_REF:0000037, GO:0000922=GO_REF:0000019, GO:0048589=GO_REF:0000019, GO:0051661=GO_REF:0000019, GO:0045665=GO_REF:0000019, GO:0001764=GO_REF:0000019} Q8IZT6 Abnormal spindle-like microcephaly-associated protein protein 20130413 {GO:0005516=IEA, GO:0048477=IEA, GO:0090263=IEA, GO:0002052=IEA, GO:0030496=IEA, GO:0005634=IEA, GO:0007283=IEA, GO:0021873=IEA, GO:0045769=IEA, GO:0005737=IEA, GO:0007067=IEA, GO:0000922=IEA, GO:0048589=IEA, GO:0051661=IEA, GO:0045665=IEA, GO:0001764=IEA} developmental growth, forebrain neuroblast division, maintenance of centrosome location, mitosis, negative regulation of asymmetric cell division, negative regulation of neuron differentiation, neuron migration, oogenesis, positive regulation of canonical Wnt receptor signaling pathway, positive regulation of neuroblast proliferation, spermatogenesis cytoplasm, midbody, nucleus, spindle pole calmodulin binding Human UniProtKB-SubCell:SL-0086 ASPRV1 UniProtKB UniProtKB {GO:0016485=PMID:16098038, GO:0006508=GO_REF:0000037, GO:0043588=GO_REF:0000024, GO:0016021=PMID:16098038, GO:0004190=PMID:16098038} Q53RT3 Retroviral-like aspartic protease 1 protein 20061121 {GO:0016485=IDA, GO:0006508=IEA, GO:0043588=ISS, GO:0016021=RCA, GO:0004190=IDA} protein processing, proteolysis, skin development integral to membrane aspartic-type endopeptidase activity Human UniProtKB:Q09PK2 ASPSCR1 IntAct UniProtKB {GO:0012506=GO_REF:0000019, GO:0005515=PMID:18775313, GO:0048471=GO_REF:0000019, GO:0042593=GO_REF:0000019, GO:0005575=GO_REF:0000015, GO:0006886=GO_REF:0000019, GO:0005829=GO_REF:0000019, GO:0008150=GO_REF:0000015, GO:0003674=GO_REF:0000015, GO:0046324=GO_REF:0000019, GO:0009898=GO_REF:0000019, GO:0016044=Reactome:REACT_11123, GO:0019898=GO_REF:0000019} Q9BZE9 Tether containing UBX domain for GLUT4 protein 20130415 {GO:0012506=IEA, GO:0005515=IPI, GO:0048471=IEA, GO:0042593=IEA, GO:0005575=ND, GO:0006886=IEA, GO:0005829=IEA, GO:0008150=ND, GO:0003674=ND, GO:0046324=IEA, GO:0009898=IEA, GO:0016044=TAS, GO:0019898=IEA} biological_process, cellular membrane organization, glucose homeostasis, intracellular protein transport, regulation of glucose import cellular_component, cytosol, extrinsic to membrane, internal side of plasma membrane, perinuclear region of cytoplasm, vesicle membrane molecular_function, protein binding Human UniProtKB:P55072 ASRGL1 HPA UniProtKB {GO:0008798=PMID:19839645, GO:0005737=GO_REF:0000024, GO:0033345=PMID:19839645, GO:0016787=GO_REF:0000002, GO:0015630=GO_REF:0000052, GO:0005730=GO_REF:0000052, GO:0004067=PMID:19839645, GO:0006508=GO_REF:0000037, GO:0003948=PMID:19839645, GO:0005634=GO_REF:0000052} Q7L266 Isoaspartyl peptidase/L-asparaginase protein 20101115 {GO:0008798=IDA, GO:0005737=ISS, GO:0033345=IDA, GO:0016787=IEA, GO:0015630=IDA, GO:0005730=IDA, GO:0004067=IDA, GO:0006508=IEA, GO:0003948=IDA, GO:0005634=IDA} asparagine catabolic process via L-aspartate, proteolysis cytoplasm, microtubule cytoskeleton, nucleolus, nucleus N4-(beta-N-acetylglucosaminyl)-L-asparaginase activity, asparaginase activity, beta-aspartyl-peptidase activity, hydrolase activity Human ASS1 InterPro UniProtKB {GO:0005515=PMID:12620389, GO:0034641=Reactome:REACT_13, GO:0005737=PMID:6194510, GO:0006526=GO_REF:0000002, GO:0000050=Reactome:REACT_847, GO:0044281=Reactome:REACT_111217, GO:0005524=GO_REF:0000002, GO:0005829=Reactome:REACT_482, GO:0004055=GO_REF:0000002} Q5T6L7 Argininosuccinate synthase protein 20130413 {GO:0005515=IPI, GO:0034641=TAS, GO:0005737=TAS, GO:0006526=IEA, GO:0000050=TAS, GO:0044281=TAS, GO:0005524=IEA, GO:0005829=TAS, GO:0004055=IEA} arginine biosynthetic process, cellular nitrogen compound metabolic process, small molecule metabolic process, urea cycle cytoplasm, cytosol ATP binding, argininosuccinate synthase activity, protein binding Human InterPro:IPR001518 ASTL MGI UniProtKB {GO:0030133=GO_REF:0000039, GO:2000360=PMID:22472438, GO:0005886=PMID:22206759, GO:0009566=PMID:22206759, GO:0005737=PMID:22206759, GO:0010954=PMID:22472438, GO:0070002=PMID:22472438, GO:0070001=PMID:22472438, GO:0006508=PMID:15087446, GO:0060468=PMID:22472438, GO:0060473=PMID:22472438, GO:0008233=PMID:15087446, GO:0008270=GO_REF:0000002, GO:0004222=PMID:15087446, GO:0007155=PMID:22206759} Q6HA08 Astacin-like metalloendopeptidase protein 20041210 {GO:0030133=IEA, GO:2000360=ISS, GO:0005886=ISS, GO:0009566=ISS, GO:0005737=ISS, GO:0010954=ISS, GO:0070002=ISS, GO:0070001=ISS, GO:0006508=IDA, GO:0060468=ISS, GO:0060473=ISS, GO:0008233=IDA, GO:0008270=IEA, GO:0004222=IDA, GO:0007155=ISS} cell adhesion, fertilization, negative regulation of binding of sperm to zona pellucida, positive regulation of protein processing, prevention of polyspermy, proteolysis cortical granule, cytoplasm, plasma membrane, transport vesicle aspartic-type peptidase activity, glutamic-type peptidase activity, metalloendopeptidase activity, peptidase activity, zinc ion binding Human ASTN1 UniProtKB UniProtKB {GO:0016477=GO_REF:0000029, GO:0007626=GO_REF:0000019, GO:0005575=GO_REF:0000015, GO:0016021=GO_REF:0000037, GO:0007158=GO_REF:0000029} O14525 Astrotactin-1 protein 20021104 {GO:0016477=NAS, GO:0007626=IEA, GO:0005575=ND, GO:0016021=IEA, GO:0007158=NAS} cell migration, locomotory behavior, neuron cell-cell adhesion cellular_component, integral to membrane Human ASUN IntAct UniProtKB {GO:0005515=PMID:20195357, GO:0007346=PMID:15737938, GO:0005737=GO_REF:0000024, GO:0007067=GO_REF:0000037, GO:0080154=GO_REF:0000024, GO:0005634=GO_REF:0000024, GO:0030317=GO_REF:0000024, GO:0051301=GO_REF:0000037} Q9NVM9 Protein asunder homolog protein 20130415 {GO:0005515=IPI, GO:0007346=IMP, GO:0005737=ISS, GO:0007067=IEA, GO:0080154=ISS, GO:0005634=ISS, GO:0030317=ISS, GO:0051301=IEA} cell division, mitosis, regulation of fertilization, regulation of mitotic cell cycle, sperm motility cytoplasm, nucleus protein binding Human UniProtKB:Q13951 ASXL1 IntAct UniProtKB {GO:0005515=PMID:22897849, GO:0000790=GO_REF:0000024, GO:0045599=GO_REF:0000024, GO:0003714=GO_REF:0000024, GO:0003713=GO_REF:0000024, GO:0035359=GO_REF:0000024, GO:0000122=GO_REF:0000024, GO:0042974=GO_REF:0000024, GO:0042975=GO_REF:0000024, GO:0003677=GO_REF:0000002, GO:0006351=GO_REF:0000037, GO:0046872=GO_REF:0000037, GO:0035517=PMID:20436459, GO:0048386=GO_REF:0000024, GO:0035522=PMID:20436459, GO:0048387=GO_REF:0000024, GO:0045944=GO_REF:0000024, GO:0032526=GO_REF:0000024} Q8IXJ9 Putative Polycomb group protein ASXL1 protein 20130415 {GO:0005515=IPI, GO:0000790=ISS, GO:0045599=ISS, GO:0003714=ISS, GO:0003713=ISS, GO:0035359=ISS, GO:0000122=ISS, GO:0042974=ISS, GO:0042975=ISS, GO:0003677=IEA, GO:0006351=IEA, GO:0046872=IEA, GO:0035517=IDA, GO:0048386=ISS, GO:0035522=IDA, GO:0048387=ISS, GO:0045944=ISS, GO:0032526=ISS} monoubiquitinated histone H2A deubiquitination, negative regulation of fat cell differentiation, negative regulation of peroxisome proliferator activated receptor signaling pathway, negative regulation of retinoic acid receptor signaling pathway, negative regulation of transcription from RNA polymerase II promoter, positive regulation of retinoic acid receptor signaling pathway, positive regulation of transcription from RNA polymerase II promoter, response to retinoic acid, transcription, DNA-dependent PR-DUB complex, nuclear chromatin DNA binding, metal ion binding, peroxisome proliferator activated receptor binding, protein binding, retinoic acid receptor binding, transcription coactivator activity, transcription corepressor activity Human UniProtKB:Q92560 ASXL2 UniProtKB UniProtKB {GO:0035360=PMID:21047783, GO:0045944=PMID:21047783, GO:0045600=PMID:21047783, GO:0005634=GO_REF:0000039, GO:0042975=PMID:21047783, GO:0003677=GO_REF:0000002, GO:0046872=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q76L83 Putative Polycomb group protein ASXL2 protein 20120308 {GO:0035360=IDA, GO:0045944=IDA, GO:0045600=IDA, GO:0005634=IEA, GO:0042975=IDA, GO:0003677=IEA, GO:0046872=IEA, GO:0006351=IEA} positive regulation of fat cell differentiation, positive regulation of peroxisome proliferator activated receptor signaling pathway, positive regulation of transcription from RNA polymerase II promoter, transcription, DNA-dependent nucleus DNA binding, metal ion binding, peroxisome proliferator activated receptor binding Human ASZ1 GOC UniProtKB {GO:0007165=PMID:12040005, GO:0005737=GO_REF:0000024, GO:0034587=GO_REF:0000024, GO:0007275=GO_REF:0000037, GO:0071546=GO_REF:0000024, GO:0004871=PMID:12040005, GO:0031047=GO_REF:0000037, GO:0007283=GO_REF:0000024, GO:0030154=GO_REF:0000037, GO:0043046=GO_REF:0000024, GO:0007140=GO_REF:0000024} Q8WWH4 Ankyrin repeat, SAM and basic leucine zipper domain-containing protein 1 protein 20130413 {GO:0007165=NAS, GO:0005737=ISS, GO:0034587=ISS, GO:0007275=IEA, GO:0071546=ISS, GO:0004871=NAS, GO:0031047=IEA, GO:0007283=ISS, GO:0030154=IEA, GO:0043046=ISS, GO:0007140=ISS} DNA methylation involved in gamete generation, cell differentiation, gene silencing by RNA, male meiosis, multicellular organismal development, piRNA metabolic process, signal transduction, spermatogenesis cytoplasm, pi-body signal transducer activity Human ATAD1 UniProtKB UniProtKB {GO:0005739=GO_REF:0000019, GO:0017111=GO_REF:0000002, GO:0030054=GO_REF:0000037, GO:0005886=GO_REF:0000037, GO:0051967=GO_REF:0000024, GO:0045211=GO_REF:0000024, GO:0007613=GO_REF:0000024, GO:0007612=GO_REF:0000024, GO:0016887=GO_REF:0000024, GO:0005524=GO_REF:0000037, GO:0005778=PMID:21525035, GO:0002092=GO_REF:0000024} Q8NBU5 ATPase family AAA domain-containing protein 1 protein 20120217 {GO:0005739=IEA, GO:0017111=IEA, GO:0030054=IEA, GO:0005886=IEA, GO:0051967=ISS, GO:0045211=ISS, GO:0007613=ISS, GO:0007612=ISS, GO:0016887=ISS, GO:0005524=IEA, GO:0005778=IDA, GO:0002092=ISS} learning, memory, negative regulation of synaptic transmission, glutamatergic, positive regulation of receptor internalization cell junction, mitochondrion, peroxisomal membrane, plasma membrane, postsynaptic membrane ATP binding, ATPase activity, nucleoside-triphosphatase activity Human UniProtKB:Q9D5T0 ATAD2 HPA UniProtKB {GO:0006355=GO_REF:0000037, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0016887=GO_REF:0000003, GO:0005524=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q6PL18 ATPase family AAA domain-containing protein 2 protein 20111111 {GO:0006355=IEA, GO:0005730=IDA, GO:0005634=IDA, GO:0016887=IEA, GO:0005524=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleolus, nucleus ATP binding, ATPase activity NOT Human ATAD2B UniProtKB UniProtKB {GO:0017111=GO_REF:0000002, GO:0070577=PMID:22464331, GO:0005524=GO_REF:0000037} Q9ULI0 ATPase family AAA domain-containing protein 2B protein 20120706 {GO:0017111=IEA, GO:0070577=IDA, GO:0005524=IEA} ATP binding, histone acetyl-lysine binding, nucleoside-triphosphatase activity Human ATAD3A UniProtKB UniProtKB {GO:0005739=PMID:20332122, GO:0042645=GO_REF:0000039, GO:0043066=PMID:20332122, GO:0017111=GO_REF:0000002, GO:0005743=GO_REF:0000039, GO:0016049=PMID:20332122, GO:0016021=GO_REF:0000037, GO:0005524=GO_REF:0000037} Q9NVI7 ATPase family AAA domain-containing protein 3A protein 20111221 {GO:0005739=IDA, GO:0042645=IEA, GO:0043066=IMP, GO:0017111=IEA, GO:0005743=IEA, GO:0016049=IMP, GO:0016021=IEA, GO:0005524=IEA} cell growth, negative regulation of apoptotic process integral to membrane, mitochondrial inner membrane, mitochondrial nucleoid, mitochondrion ATP binding, nucleoside-triphosphatase activity Human ATAD3B UniProtKB UniProtKB {GO:0017111=GO_REF:0000002, GO:0005743=GO_REF:0000039, GO:0005524=GO_REF:0000037} Q5T9A4 ATPase family AAA domain-containing protein 3B protein 20130413 {GO:0017111=IEA, GO:0005743=IEA, GO:0005524=IEA} mitochondrial inner membrane ATP binding, nucleoside-triphosphatase activity Human UniProtKB-SubCell:SL-0168 ATAD3C UniProtKB UniProtKB {GO:0017111=GO_REF:0000002, GO:0005524=GO_REF:0000037} Q5T2N8 ATPase family AAA domain-containing protein 3C protein 20130413 {GO:0017111=IEA, GO:0005524=IEA} ATP binding, nucleoside-triphosphatase activity Human UniProtKB-KW:KW-0067 ATAD5 UniProtKB UniProtKB {GO:0017111=GO_REF:0000002, GO:0005634=GO_REF:0000039, GO:0005524=GO_REF:0000037, GO:0006974=GO_REF:0000037} Q96QE3 ATPase family AAA domain-containing protein 5 protein 20130413 {GO:0017111=IEA, GO:0005634=IEA, GO:0005524=IEA, GO:0006974=IEA} response to DNA damage stimulus nucleus ATP binding, nucleoside-triphosphatase activity Human UniProtKB-SubCell:SL-0191 ATAT1 UniProtKB UniProtKB {GO:0019799=PMID:20829795, GO:0071929=GO_REF:0000002} Q5SQI0 Alpha-tubulin N-acetyltransferase protein 20100915 {GO:0019799=IMP, GO:0071929=IEA} alpha-tubulin acetylation tubulin N-acetyltransferase activity Human ATCAY IntAct UniProtKB {GO:0005515=PMID:16275660, GO:0048311=GO_REF:0000024, GO:0043005=PMID:16899818, GO:0030424=GO_REF:0000024, GO:0031966=GO_REF:0000024, GO:0030054=GO_REF:0000037, GO:0045202=GO_REF:0000024, GO:0031175=GO_REF:0000024, GO:0030425=GO_REF:0000024, GO:0005739=PMID:16899818, GO:0032880=PMID:16899818, GO:0005737=PMID:16899818, GO:2000212=PMID:16899818, GO:0006810=GO_REF:0000037, GO:0019894=PMID:19861499} Q86WG3 Caytaxin protein 20130415 {GO:0005515=IPI, GO:0048311=ISS, GO:0043005=IDA, GO:0030424=ISS, GO:0031966=ISS, GO:0030054=IEA, GO:0045202=ISS, GO:0031175=ISS, GO:0030425=ISS, GO:0005739=IDA, GO:0032880=IDA, GO:0005737=IDA, GO:2000212=IDA, GO:0006810=IEA, GO:0019894=IPI} mitochondrion distribution, negative regulation of glutamate metabolic process, neuron projection development, regulation of protein localization, transport axon, cell junction, cytoplasm, dendrite, mitochondrial membrane, mitochondrion, neuron projection, synapse kinesin binding, protein binding Human UniProtKB:Q9UNE7 ATE1 InterPro UniProtKB {GO:0005737=PMID:9858543, GO:0004057=GO_REF:0000002, GO:0005634=PMID:9858543, GO:0016598=GO_REF:0000002} Q5SQQ1 Arginyl-tRNA--protein transferase 1 protein 20130413 {GO:0005737=IDA, GO:0004057=IEA, GO:0005634=IDA, GO:0016598=IEA} protein arginylation cytoplasm, nucleus arginyltransferase activity Human InterPro:IPR007471 ATF1 Reactome UniProtKB {GO:0005667=GO_REF:0000019, GO:0048011=Reactome:REACT_11061, GO:0038124=Reactome:REACT_8006, GO:0003700=GO_REF:0000002, GO:0034142=Reactome:REACT_6894, GO:0038123=Reactome:REACT_8005, GO:0034134=Reactome:REACT_7980, GO:0005634=PMID:8798441, GO:0002224=Reactome:REACT_9020, GO:0051403=Reactome:REACT_21308, GO:0003677=GO_REF:0000019, GO:0006351=GO_REF:0000037, GO:0043565=GO_REF:0000002, GO:0002756=Reactome:REACT_6809, GO:0045087=Reactome:REACT_6802, GO:0002755=Reactome:REACT_27215, GO:0034166=Reactome:REACT_9027, GO:0005654=Reactome:REACT_12437, GO:0035666=Reactome:REACT_25281, GO:0034146=Reactome:REACT_9061, GO:0034138=Reactome:REACT_6783, GO:0034162=Reactome:REACT_9047} P18846 Cyclic AMP-dependent transcription factor ATF-1 protein 20130301 {GO:0005667=IEA, GO:0048011=TAS, GO:0038124=TAS, GO:0003700=IEA, GO:0034142=TAS, GO:0038123=TAS, GO:0034134=TAS, GO:0005634=IDA, GO:0002224=TAS, GO:0051403=TAS, GO:0003677=IEA, GO:0006351=IEA, GO:0043565=IEA, GO:0002756=TAS, GO:0045087=TAS, GO:0002755=TAS, GO:0034166=TAS, GO:0005654=TAS, GO:0035666=TAS, GO:0034146=TAS, GO:0034138=TAS, GO:0034162=TAS} MyD88-dependent toll-like receptor signaling pathway, MyD88-independent toll-like receptor signaling pathway, TRIF-dependent toll-like receptor signaling pathway, innate immune response, neurotrophin TRK receptor signaling pathway, stress-activated MAPK cascade, toll-like receptor 10 signaling pathway, toll-like receptor 2 signaling pathway, toll-like receptor 3 signaling pathway, toll-like receptor 4 signaling pathway, toll-like receptor 5 signaling pathway, toll-like receptor 9 signaling pathway, toll-like receptor TLR1:TLR2 signaling pathway, toll-like receptor TLR6:TLR2 signaling pathway, toll-like receptor signaling pathway, transcription, DNA-dependent nucleoplasm, nucleus, transcription factor complex DNA binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity Human ATF2 HPA UniProtKB {GO:0005515=PMID:22439931, GO:0034142=Reactome:REACT_6894, GO:0003700=GO_REF:0000002, GO:0006366=PMID:19861239, GO:0035497=PMID:19861239, GO:0003705=PMID:19861239, GO:0032915=GO_REF:0000019, GO:0005634=GO_REF:0000052, GO:0051403=Reactome:REACT_21308, GO:0051090=Reactome:REACT_21326, GO:0002756=Reactome:REACT_6809, GO:0008140=PMID:19861239, GO:0002755=Reactome:REACT_27215, GO:0045444=GO_REF:0000019, GO:0034138=Reactome:REACT_6783, GO:0001102=PMID:19861239, GO:0038124=Reactome:REACT_8006, GO:0006357=PMID:19861239, GO:0038123=Reactome:REACT_8005, GO:0046982=GO_REF:0000019, GO:0019901=PMID:21098032, GO:0034134=Reactome:REACT_7980, GO:0003713=PMID:2529117, GO:0005730=GO_REF:0000052, GO:0006970=PMID:21098032, GO:0003676=GO_REF:0000002, GO:0002224=Reactome:REACT_9020, GO:0003151=GO_REF:0000019, GO:0043565=GO_REF:0000002, GO:0001077=GO_REF:0000019, GO:0001076=PMID:19861239, GO:0016020=GO_REF:0000019, GO:0045087=Reactome:REACT_6802, GO:0003682=GO_REF:0000019, GO:0000980=PMID:19861239, GO:0008270=GO_REF:0000002, GO:0035666=Reactome:REACT_25281, GO:0034166=Reactome:REACT_9027, GO:0005654=Reactome:REACT_6839, GO:0034146=Reactome:REACT_9061, GO:0060612=GO_REF:0000019, GO:0034162=Reactome:REACT_9047} Q3B7B7 Cyclic AMP-dependent transcription factor ATF-2 protein 20100326 {GO:0005515=IPI, GO:0034142=TAS, GO:0003700=IEA, GO:0006366=IC, GO:0035497=IDA, GO:0003705=IC, GO:0032915=IEA, GO:0005634=IDA, GO:0051403=TAS, GO:0051090=TAS, GO:0002756=TAS, GO:0008140=IDA, GO:0002755=TAS, GO:0045444=IEA, GO:0034138=TAS, GO:0001102=IPI, GO:0038124=TAS, GO:0006357=IC, GO:0038123=TAS, GO:0046982=IEA, GO:0019901=IPI, GO:0034134=TAS, GO:0003713=TAS, GO:0005730=IDA, GO:0006970=IDA, GO:0003676=IEA, GO:0002224=TAS, GO:0003151=IEA, GO:0043565=IEA, GO:0001077=IEA, GO:0001076=IC, GO:0016020=IEA, GO:0045087=TAS, GO:0003682=IEA, GO:0000980=IDA, GO:0008270=IEA, GO:0035666=TAS, GO:0034166=TAS, GO:0005654=TAS, GO:0034146=TAS, GO:0060612=IEA, GO:0034162=TAS} MyD88-dependent toll-like receptor signaling pathway, MyD88-independent toll-like receptor signaling pathway, TRIF-dependent toll-like receptor signaling pathway, adipose tissue development, fat cell differentiation, innate immune response, outflow tract morphogenesis, positive regulation of transforming growth factor beta2 production, regulation of sequence-specific DNA binding transcription factor activity, regulation of transcription from RNA polymerase II promoter, response to osmotic stress, stress-activated MAPK cascade, toll-like receptor 10 signaling pathway, toll-like receptor 2 signaling pathway, toll-like receptor 3 signaling pathway, toll-like receptor 4 signaling pathway, toll-like receptor 5 signaling pathway, toll-like receptor 9 signaling pathway, toll-like receptor TLR1:TLR2 signaling pathway, toll-like receptor TLR6:TLR2 signaling pathway, toll-like receptor signaling pathway, transcription from RNA polymerase II promoter membrane, nucleolus, nucleoplasm, nucleus RNA polymerase II activating transcription factor binding, RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription, RNA polymerase II distal enhancer sequence-specific DNA binding, RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity, RNA polymerase II transcription factor binding transcription factor activity, cAMP response element binding, cAMP response element binding protein binding, chromatin binding, nucleic acid binding, protein binding, protein heterodimerization activity, protein kinase binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, transcription coactivator activity, zinc ion binding NOT Human ATF3 HPA UniProtKB {GO:0005515=PMID:18255255, GO:0008284=GO_REF:0000019, GO:0003700=GO_REF:0000002, GO:0003714=PMID:7515060, GO:0006950=GO_REF:0000019, GO:0005730=GO_REF:0000052, GO:0006094=GO_REF:0000019, GO:0005634=GO_REF:0000052, GO:0006351=GO_REF:0000037, GO:0030968=Reactome:REACT_18356, GO:0042802=PMID:18255255, GO:0043565=GO_REF:0000002, GO:0005654=Reactome:REACT_115743, GO:0006987=Reactome:REACT_18277, GO:0045892=GO_REF:0000019, GO:0044267=Reactome:REACT_17015} Q5VTZ4 Cyclic AMP-dependent transcription factor ATF-3 protein 20080818 {GO:0005515=IPI, GO:0008284=IEA, GO:0003700=IEA, GO:0003714=TAS, GO:0006950=IEA, GO:0005730=IDA, GO:0006094=IEA, GO:0005634=IDA, GO:0006351=IEA, GO:0030968=TAS, GO:0042802=IPI, GO:0043565=IEA, GO:0005654=TAS, GO:0006987=TAS, GO:0045892=IEA, GO:0044267=TAS} activation of signaling protein activity involved in unfolded protein response, cellular protein metabolic process, endoplasmic reticulum unfolded protein response, gluconeogenesis, negative regulation of transcription, DNA-dependent, positive regulation of cell proliferation, response to stress, transcription, DNA-dependent nucleolus, nucleoplasm, nucleus identical protein binding, protein binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, transcription corepressor activity Human ATF4 BHF-UCL UniProtKB {GO:0005515=PMID:12812986, GO:0034976=PMID:19061639, GO:0003700=PMID:12689582, GO:0006366=GO_REF:0000024, GO:0006094=GO_REF:0000024, GO:0043267=GO_REF:0000019, GO:0005634=PMID:16682973, GO:0030968=Reactome:REACT_18356, GO:0005737=GO_REF:0000024, GO:0043525=GO_REF:0000024, GO:0045944=PMID:15788408, GO:0005667=GO_REF:0000019, GO:0006520=PMID:12689582, GO:0006355=GO_REF:0000024, GO:0005815=GO_REF:0000039, GO:0007214=GO_REF:0000019, GO:0008022=GO_REF:0000019, GO:0003677=PMID:18940792, GO:0043565=GO_REF:0000002, GO:0032590=GO_REF:0000019, GO:0070059=GO_REF:0000024, GO:0005654=Reactome:REACT_18270, GO:0045893=PMID:15775988, GO:0006987=Reactome:REACT_18277, GO:0044267=Reactome:REACT_17015} P18848 Cyclic AMP-dependent transcription factor ATF-4 protein 20090601 {GO:0005515=IPI, GO:0034976=IDA, GO:0003700=TAS, GO:0006366=ISS, GO:0006094=ISS, GO:0043267=IEA, GO:0005634=IDA, GO:0030968=TAS, GO:0005737=ISS, GO:0043525=ISS, GO:0045944=IMP, GO:0005667=IEA, GO:0006520=TAS, GO:0006355=ISS, GO:0005815=IEA, GO:0007214=IEA, GO:0008022=IEA, GO:0003677=IDA, GO:0043565=IEA, GO:0032590=IEA, GO:0070059=ISS, GO:0005654=TAS, GO:0045893=IDA, GO:0006987=TAS, GO:0044267=TAS} activation of signaling protein activity involved in unfolded protein response, cellular amino acid metabolic process, cellular protein metabolic process, endoplasmic reticulum unfolded protein response, gamma-aminobutyric acid signaling pathway, gluconeogenesis, intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress, negative regulation of potassium ion transport, positive regulation of neuron apoptotic process, positive regulation of transcription from RNA polymerase II promoter, positive regulation of transcription, DNA-dependent, regulation of transcription, DNA-dependent, response to endoplasmic reticulum stress, transcription from RNA polymerase II promoter cytoplasm, dendrite membrane, microtubule organizing center, nucleoplasm, nucleus, transcription factor complex DNA binding, protein C-terminus binding, protein binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity Human ATF5 HPA UniProtKB {GO:0005515=PMID:10373550, GO:0005667=GO_REF:0000019, GO:0043066=GO_REF:0000019, GO:0003700=GO_REF:0000002, GO:0006357=GO_REF:0000019, GO:0003714=PMID:10373550, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0006351=GO_REF:0000037, GO:0043565=GO_REF:0000002, GO:0048712=GO_REF:0000019, GO:0005737=GO_REF:0000052, GO:0031072=GO_REF:0000019} Q9Y2D1 Cyclic AMP-dependent transcription factor ATF-5 protein 20101115 {GO:0005515=IPI, GO:0005667=IEA, GO:0043066=IEA, GO:0003700=IEA, GO:0006357=IEA, GO:0003714=TAS, GO:0005730=IDA, GO:0005634=IDA, GO:0006351=IEA, GO:0043565=IEA, GO:0048712=IEA, GO:0005737=IDA, GO:0031072=IEA} negative regulation of apoptotic process, negative regulation of astrocyte differentiation, regulation of transcription from RNA polymerase II promoter, transcription, DNA-dependent cytoplasm, nucleolus, nucleus, transcription factor complex heat shock protein binding, protein binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, transcription corepressor activity Human ATF6 BHF-UCL UniProtKB {GO:0005515=PMID:16469704, GO:0003700=GO_REF:0000002, GO:0006357=PMID:10564271, GO:0006990=PMID:9837962, GO:0003713=PMID:10866666, GO:0006950=PMID:10866666, GO:0005634=PMID:10564271, GO:0005635=PMID:10866666, GO:0006351=GO_REF:0000037, GO:0030968=PMID:19816510, GO:0043565=GO_REF:0000002, GO:0007165=PMID:9271374, GO:0000139=Reactome:REACT_18431, GO:0006457=PMID:10564271, GO:0005789=Reactome:REACT_18431, GO:0005654=Reactome:REACT_18286, GO:0016021=GO_REF:0000037, GO:0006987=Reactome:REACT_18348, GO:0044267=Reactome:REACT_17015} P18850 Cyclic AMP-dependent transcription factor ATF-6 alpha protein 20100107 {GO:0005515=IPI, GO:0003700=IEA, GO:0006357=TAS, GO:0006990=TAS, GO:0003713=TAS, GO:0006950=TAS, GO:0005634=TAS, GO:0005635=TAS, GO:0006351=IEA, GO:0030968=TAS, GO:0043565=IEA, GO:0007165=TAS, GO:0000139=TAS, GO:0006457=TAS, GO:0005789=TAS, GO:0005654=TAS, GO:0016021=IEA, GO:0006987=TAS, GO:0044267=TAS} activation of signaling protein activity involved in unfolded protein response, cellular protein metabolic process, endoplasmic reticulum unfolded protein response, positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response, protein folding, regulation of transcription from RNA polymerase II promoter, response to stress, signal transduction, transcription, DNA-dependent Golgi membrane, endoplasmic reticulum membrane, integral to membrane, nuclear envelope, nucleoplasm, nucleus protein binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, transcription coactivator activity Human ATF6B HPA UniProtKB {GO:0005622=PMID:8870652, GO:0006986=GO_REF:0000037, GO:0043565=GO_REF:0000002, GO:0007165=PMID:8586413, GO:0003700=GO_REF:0000002, GO:0005730=GO_REF:0000052, GO:0005789=GO_REF:0000039, GO:0005634=GO_REF:0000052, GO:0016021=GO_REF:0000037, GO:0005925=GO_REF:0000052, GO:0006351=GO_REF:0000037} Q99941 Cyclic AMP-dependent transcription factor ATF-6 beta protein 20120912 {GO:0005622=IDA, GO:0006986=IEA, GO:0043565=IEA, GO:0007165=TAS, GO:0003700=IEA, GO:0005730=IDA, GO:0005789=IEA, GO:0005634=IDA, GO:0016021=IEA, GO:0005925=IDA, GO:0006351=IEA} response to unfolded protein, signal transduction, transcription, DNA-dependent endoplasmic reticulum membrane, focal adhesion, integral to membrane, intracellular, nucleolus, nucleus sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity Human ATF7 HPA UniProtKB {GO:0005515=PMID:20195357, GO:0006355=PMID:8288576, GO:0003700=GO_REF:0000002, GO:0005634=GO_REF:0000052, GO:0003676=GO_REF:0000002, GO:0006351=GO_REF:0000037, GO:0043565=GO_REF:0000002, GO:0005737=GO_REF:0000052, GO:0034399=PMID:17264123, GO:0019048=GO_REF:0000037, GO:0008270=GO_REF:0000002, GO:0005654=GO_REF:0000039, GO:0051019=PMID:10376527, GO:0008134=PMID:10376527} P17544 Cyclic AMP-dependent transcription factor ATF-7 protein 20101115 {GO:0005515=IPI, GO:0006355=IDA, GO:0003700=IEA, GO:0005634=IDA, GO:0003676=IEA, GO:0006351=IEA, GO:0043565=IEA, GO:0005737=IDA, GO:0034399=IDA, GO:0019048=IEA, GO:0008270=IEA, GO:0005654=IEA, GO:0051019=IDA, GO:0008134=IDA} regulation of transcription, DNA-dependent, transcription, DNA-dependent, virus-host interaction cytoplasm, nuclear periphery, nucleoplasm, nucleus mitogen-activated protein kinase binding, nucleic acid binding, protein binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, transcription factor binding, zinc ion binding Human ATF7IP IntAct UniProtKB {GO:0006306=PMID:12665582, GO:0005515=PMID:12812986, GO:0005667=GO_REF:0000019, GO:0045898=PMID:12665582, GO:0019048=GO_REF:0000037, GO:0003714=GO_REF:0000019, GO:0005634=PMID:12665582, GO:0000122=GO_REF:0000019, GO:0045893=PMID:12665582, GO:0045892=PMID:12665582, GO:0016887=GO_REF:0000019, GO:0006351=GO_REF:0000037} Q6VMQ6 Activating transcription factor 7-interacting protein 1 protein 20130415 {GO:0006306=IDA, GO:0005515=IPI, GO:0005667=IEA, GO:0045898=IDA, GO:0019048=IEA, GO:0003714=IEA, GO:0005634=IDA, GO:0000122=IEA, GO:0045893=IDA, GO:0045892=IDA, GO:0016887=IEA, GO:0006351=IEA} DNA methylation, negative regulation of transcription from RNA polymerase II promoter, negative regulation of transcription, DNA-dependent, positive regulation of transcription, DNA-dependent, regulation of RNA polymerase II transcriptional preinitiation complex assembly, transcription, DNA-dependent, virus-host interaction nucleus, transcription factor complex ATPase activity, protein binding, transcription corepressor activity Human UniProtKB:Q9NRI5 ATF7IP2 HPA UniProtKB {GO:0005737=GO_REF:0000052, GO:0006355=GO_REF:0000037, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0006351=GO_REF:0000037} Q5U623 Activating transcription factor 7-interacting protein 2 protein 20111111 {GO:0005737=IDA, GO:0006355=IEA, GO:0005730=IDA, GO:0005634=IDA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent cytoplasm, nucleolus, nucleus Human ATG10 LIFEdb UniProtKB {GO:0005622=GO_REF:0000054, GO:0005737=GO_REF:0000039, GO:0019777=PMID:20723759, GO:0006914=PMID:15657430, GO:0006497=GO_REF:0000024, GO:0032446=PMID:16963840, GO:0034263=PMID:17256008, GO:0015031=GO_REF:0000037, GO:0031401=GO_REF:0000024} Q9H0Y0 Ubiquitin-like-conjugating enzyme ATG10 protein 20100607 {GO:0005622=IDA, GO:0005737=IEA, GO:0019777=ISS, GO:0006914=IMP, GO:0006497=ISS, GO:0032446=IDA, GO:0034263=IMP, GO:0015031=IEA, GO:0031401=ISS} autophagy, autophagy in response to ER overload, positive regulation of protein modification process, protein lipidation, protein modification by small protein conjugation, protein transport cytoplasm, intracellular Atg12 ligase activity Human ATG12 Reactome UniProtKB {GO:0005515=PMID:11096062, GO:0043234=GO_REF:0000019, GO:0034045=GO_REF:0000024, GO:0005737=GO_REF:0000002, GO:0045087=Reactome:REACT_6802, GO:0000045=GO_REF:0000024, GO:0032480=Reactome:REACT_25271} O94817 Ubiquitin-like protein ATG12 protein 20100819 {GO:0005515=IPI, GO:0043234=IEA, GO:0034045=ISS, GO:0005737=IEA, GO:0045087=TAS, GO:0000045=ISS, GO:0032480=TAS} autophagic vacuole assembly, innate immune response, negative regulation of type I interferon production cytoplasm, pre-autophagosomal structure membrane, protein complex protein binding Human ATG13 IntAct UniProtKB {GO:0005515=PMID:20562859, GO:0070969=PMID:19211835, GO:0019901=PMID:18936157, GO:0000407=GO_REF:0000024, GO:0000045=PMID:19211835, GO:0005829=GO_REF:0000039} O75143 Autophagy-related protein 13 protein 20130415 {GO:0005515=IPI, GO:0070969=IPI, GO:0019901=IPI, GO:0000407=ISS, GO:0000045=IMP, GO:0005829=IEA} autophagic vacuole assembly ULK1-ATG13-FIP200 complex, cytosol, pre-autophagosomal structure protein binding, protein kinase binding Human UniProtKB:Q9H0R8 ATG14 UniProtKB UniProtKB {GO:0005515=PMID:19270696, GO:0034045=PMID:19270696, GO:0005776=PMID:19270696, GO:0005783=GO_REF:0000039, GO:0000045=PMID:19270696, GO:0010508=GO_REF:0000002} Q6ZNE5 Beclin 1-associated autophagy-related key regulator protein 20100625 {GO:0005515=IPI, GO:0034045=IDA, GO:0005776=IDA, GO:0005783=IEA, GO:0000045=IMP, GO:0010508=IEA} autophagic vacuole assembly, positive regulation of autophagy autophagic vacuole, endoplasmic reticulum, pre-autophagosomal structure membrane protein binding Human UniProtKB:Q99570 ATG16L1 IntAct UniProtKB {GO:0005515=PMID:20562859, GO:0034045=GO_REF:0000039, GO:0005776=PMID:15620219, GO:0000421=GO_REF:0000019, GO:0051260=PMID:15620219, GO:0000045=PMID:15620219, GO:0015031=GO_REF:0000037} Q676U5 Autophagy-related protein 16-1 protein 20130415 {GO:0005515=IPI, GO:0034045=IEA, GO:0005776=ISS, GO:0000421=IEA, GO:0051260=NAS, GO:0000045=NAS, GO:0015031=IEA} autophagic vacuole assembly, protein homooligomerization, protein transport autophagic vacuole, autophagic vacuole membrane, pre-autophagosomal structure membrane protein binding Human UniProtKB:Q9GZQ8 ATG16L2 UniProtKB UniProtKB {GO:0005737=GO_REF:0000039, GO:0006914=GO_REF:0000037, GO:0015031=GO_REF:0000037} Q8NAA4 Autophagy-related protein 16-2 protein 20130413 {GO:0005737=IEA, GO:0006914=IEA, GO:0015031=IEA} autophagy, protein transport cytoplasm Human UniProtKB-SubCell:SL-0086 ATG2A IntAct UniProtKB {GO:0005515=PMID:20562859, GO:0006914=GO_REF:0000002} Q2TAZ0 Autophagy-related protein 2 homolog A protein 20130415 {GO:0005515=IPI, GO:0006914=IEA} autophagy protein binding Human UniProtKB:Q9H0R8 ATG2B InterPro UniProtKB {GO:0006914=GO_REF:0000002} Q96BY7 Autophagy-related protein 2 homolog B protein 20130413 {GO:0006914=IEA} autophagy Human InterPro:IPR026849 ATG3 IntAct UniProtKB {GO:0005515=PMID:20562859, GO:0016567=PMID:11825910, GO:0019787=PMID:11825910, GO:0006612=GO_REF:0000024, GO:0019776=GO_REF:0000024, GO:0019777=GO_REF:0000024, GO:0019899=PMID:11825910, GO:0000045=GO_REF:0000024, GO:0043653=GO_REF:0000024, GO:0006464=PMID:11825910, GO:0000153=PMID:11825910, GO:0005829=PMID:11825910} Q9NT62 Ubiquitin-like-conjugating enzyme ATG3 protein 20130415 {GO:0005515=IPI, GO:0016567=IDA, GO:0019787=IDA, GO:0006612=ISS, GO:0019776=ISS, GO:0019777=ISS, GO:0019899=IPI, GO:0000045=ISS, GO:0043653=ISS, GO:0006464=IDA, GO:0000153=IPI, GO:0005829=IDA} autophagic vacuole assembly, cellular protein modification process, mitochondrial fragmentation involved in apoptotic process, protein targeting to membrane, protein ubiquitination cytoplasmic ubiquitin ligase complex, cytosol Atg12 ligase activity, Atg8 ligase activity, enzyme binding, protein binding, small conjugating protein ligase activity Human UniProtKB:Q9H0R8 ATG4A MGI UniProtKB {GO:0005737=PMID:12446702, GO:0006914=GO_REF:0000037, GO:0006508=PMID:12473658, GO:0008234=PMID:12473658, GO:0015031=GO_REF:0000037} Q8WYN0 Cysteine protease ATG4A protein 20060110 {GO:0005737=ISS, GO:0006914=IEA, GO:0006508=IDA, GO:0008234=IDA, GO:0015031=IEA} autophagy, protein transport, proteolysis cytoplasm cysteine-type peptidase activity Human ATG4B BHF-UCL UniProtKB {GO:0005515=PMID:20562859, GO:0005737=PMID:12446702, GO:0004175=PMID:18387192, GO:0006914=PMID:12446702, GO:0006508=PMID:18387192, GO:0008234=PMID:15169837, GO:0000045=PMID:12446702, GO:0015031=GO_REF:0000037, GO:0010508=PMID:18387192} Q9Y4P1 Cysteine protease ATG4B protein 20130219 {GO:0005515=IPI, GO:0005737=ISS, GO:0004175=IDA, GO:0006914=IGI, GO:0006508=IDA, GO:0008234=IDA, GO:0000045=IGI, GO:0015031=IEA, GO:0010508=IDA} autophagic vacuole assembly, autophagy, positive regulation of autophagy, protein transport, proteolysis cytoplasm cysteine-type peptidase activity, endopeptidase activity, protein binding Human ATG4C UniProtKB UniProtKB {GO:0004197=PMID:12446702, GO:0005737=PMID:12446702, GO:0006612=PMID:12446702, GO:0006914=PMID:12446702, GO:0006508=PMID:12446702, GO:0005576=PMID:12446702, GO:0008233=PMID:12446702, GO:0008234=GO_REF:0000038, GO:0000045=PMID:12446702, GO:0015031=GO_REF:0000038, GO:0005829=PMID:12446702} Q96DT6 Cysteine protease ATG4C protein 20090421 {GO:0004197=IMP, GO:0005737=ISS, GO:0006612=ISS, GO:0006914=IGI, GO:0006508=IDA, GO:0005576=IDA, GO:0008233=IDA, GO:0008234=IEA, GO:0000045=IGI, GO:0015031=IEA, GO:0005829=ISS} autophagic vacuole assembly, autophagy, protein targeting to membrane, protein transport, proteolysis cytoplasm, cytosol, extracellular region cysteine-type endopeptidase activity, cysteine-type peptidase activity, peptidase activity Human UniProtKB:P53867 ATG4D UniProtKB UniProtKB {GO:0004197=PMID:12446702, GO:0005737=GO_REF:0000038, GO:0006914=GO_REF:0000038, GO:0006508=GO_REF:0000038, GO:0008234=GO_REF:0000038, GO:0015031=GO_REF:0000038} Q969K0 Cysteine protease ATG4D protein 20130413 {GO:0004197=ISS, GO:0005737=IEA, GO:0006914=IEA, GO:0006508=IEA, GO:0008234=IEA, GO:0015031=IEA} autophagy, protein transport, proteolysis cytoplasm cysteine-type endopeptidase activity, cysteine-type peptidase activity Human UniProtKB-KW:KW-0653 ATG5 IntAct UniProtKB {GO:0005515=PMID:20562859, GO:0043066=GO_REF:0000019, GO:0060047=GO_REF:0000019, GO:0005776=PMID:15292400, GO:0042493=GO_REF:0000019, GO:0006914=GO_REF:0000024, GO:0006915=GO_REF:0000037, GO:0005737=GO_REF:0000024, GO:0034045=GO_REF:0000024, GO:0001974=GO_REF:0000019, GO:0048840=GO_REF:0000019, GO:0045087=Reactome:REACT_6802, GO:0042311=GO_REF:0000019, GO:0055015=GO_REF:0000019, GO:0031397=GO_REF:0000019, GO:0000045=GO_REF:0000024, GO:0032480=Reactome:REACT_25271, GO:0043687=GO_REF:0000024} Q9H1Y0 Autophagy protein 5 protein 20130415 {GO:0005515=IPI, GO:0043066=IEA, GO:0060047=IEA, GO:0005776=IDA, GO:0042493=IEA, GO:0006914=ISS, GO:0006915=IEA, GO:0005737=ISS, GO:0034045=ISS, GO:0001974=IEA, GO:0048840=IEA, GO:0045087=TAS, GO:0042311=IEA, GO:0055015=IEA, GO:0031397=IEA, GO:0000045=ISS, GO:0032480=TAS, GO:0043687=ISS} apoptotic process, autophagic vacuole assembly, autophagy, blood vessel remodeling, heart contraction, innate immune response, negative regulation of apoptotic process, negative regulation of protein ubiquitination, negative regulation of type I interferon production, otolith development, post-translational protein modification, response to drug, vasodilation, ventricular cardiac muscle cell development autophagic vacuole, cytoplasm, pre-autophagosomal structure membrane protein binding Human UniProtKB:Q9GZQ8 ATG7 BHF-UCL UniProtKB {GO:0005515=PMID:21903422, GO:0021987=GO_REF:0000019, GO:0009791=GO_REF:0000019, GO:0015031=GO_REF:0000037, GO:0021860=GO_REF:0000019, GO:0042803=PMID:11096062, GO:0031401=PMID:12890687, GO:0030163=GO_REF:0000019, GO:0005737=GO_REF:0000052, GO:0042594=GO_REF:0000019, GO:0021680=GO_REF:0000019, GO:0006497=PMID:12890687, GO:0007628=GO_REF:0000019, GO:0031396=GO_REF:0000019, GO:0016239=PMID:22354037, GO:0006520=GO_REF:0000019, GO:0043066=GO_REF:0000019, GO:0006996=GO_REF:0000019, GO:0021955=GO_REF:0000019, GO:0006914=GO_REF:0000019, GO:0004839=GO_REF:0000019, GO:0032446=GO_REF:0000019, GO:0001889=GO_REF:0000019, GO:0006944=PMID:10233149, GO:0019778=PMID:20723759, GO:0050877=GO_REF:0000019, GO:0055013=GO_REF:0000019, GO:0006464=PMID:10233149, GO:0016044=GO_REF:0000019} O95352 Ubiquitin-like modifier-activating enzyme ATG7 protein 20120531 {GO:0005515=IPI, GO:0021987=IEA, GO:0009791=IEA, GO:0015031=IEA, GO:0021860=IEA, GO:0042803=IDA, GO:0031401=IDA, GO:0030163=IEA, GO:0005737=IDA, GO:0042594=IEA, GO:0021680=IEA, GO:0006497=IDA, GO:0007628=IEA, GO:0031396=IEA, GO:0016239=IMP, GO:0006520=IEA, GO:0043066=IEA, GO:0006996=IEA, GO:0021955=IEA, GO:0006914=IEA, GO:0004839=IEA, GO:0032446=IEA, GO:0001889=IEA, GO:0006944=TAS, GO:0019778=ISS, GO:0050877=IEA, GO:0055013=IEA, GO:0006464=TAS, GO:0016044=IEA} adult walking behavior, autophagy, cardiac muscle cell development, cellular amino acid metabolic process, cellular membrane fusion, cellular membrane organization, cellular protein modification process, central nervous system neuron axonogenesis, cerebellar Purkinje cell layer development, cerebral cortex development, liver development, negative regulation of apoptotic process, neurological system process, organelle organization, positive regulation of macroautophagy, positive regulation of protein modification process, post-embryonic development, protein catabolic process, protein lipidation, protein modification by small protein conjugation, protein transport, pyramidal neuron development, regulation of protein ubiquitination, response to starvation cytoplasm APG12 activating enzyme activity, protein binding, protein homodimerization activity, ubiquitin activating enzyme activity Human ATG9A IntAct UniProtKB {GO:0005515=PMID:21903422, GO:0005776=GO_REF:0000019, GO:0005794=GO_REF:0000039, GO:0005770=GO_REF:0000019, GO:0000421=GO_REF:0000039, GO:0006914=GO_REF:0000019, GO:0031410=GO_REF:0000037, GO:0015031=GO_REF:0000037, GO:0034067=GO_REF:0000019, GO:0045087=GO_REF:0000019, GO:0031902=GO_REF:0000039, GO:0016021=GO_REF:0000037, GO:0000045=PMID:15755735} Q7Z3C6 Autophagy-related protein 9A protein 20130415 {GO:0005515=IPI, GO:0005776=IEA, GO:0005794=IEA, GO:0005770=IEA, GO:0000421=IEA, GO:0006914=IEA, GO:0031410=IEA, GO:0015031=IEA, GO:0034067=IEA, GO:0045087=IEA, GO:0031902=IEA, GO:0016021=IEA, GO:0000045=IMP} autophagic vacuole assembly, autophagy, innate immune response, protein localization to Golgi apparatus, protein transport Golgi apparatus, autophagic vacuole, autophagic vacuole membrane, cytoplasmic vesicle, integral to membrane, late endosome, late endosome membrane protein binding Human UniProtKB:Q9UHD2 ATG9B MGI UniProtKB {GO:0000421=GO_REF:0000039, GO:0031410=GO_REF:0000037, GO:0016021=GO_REF:0000037, GO:0000045=PMID:15755735} Q674R7 Autophagy-related protein 9B protein 20060210 {GO:0000421=IEA, GO:0031410=IEA, GO:0016021=IEA, GO:0000045=IDA} autophagic vacuole assembly autophagic vacuole membrane, cytoplasmic vesicle, integral to membrane Human ATHL1 UniProtKB UniProtKB {GO:0005975=GO_REF:0000002, GO:0016798=GO_REF:0000037, GO:0003824=GO_REF:0000002} Q32M88 Acid trehalase-like protein 1 protein 20130413 {GO:0005975=IEA, GO:0016798=IEA, GO:0003824=IEA} carbohydrate metabolic process catalytic activity, hydrolase activity, acting on glycosyl bonds Human UniProtKB-KW:KW-0326 ATIC Reactome UniProtKB {GO:0009168=Reactome:REACT_1776, GO:0021987=GO_REF:0000019, GO:0003360=GO_REF:0000019, GO:0003937=Reactome:REACT_263, GO:0031100=GO_REF:0000019, GO:0055086=Reactome:REACT_1698, GO:0021549=GO_REF:0000019, GO:0044281=Reactome:REACT_111217, GO:0042803=PMID:14966129, GO:0005829=Reactome:REACT_812, GO:0005739=GO_REF:0000019, GO:0004643=Reactome:REACT_812, GO:0006139=PMID:8567683, GO:0046452=GO_REF:0000019, GO:0010035=GO_REF:0000019, GO:0006144=Reactome:REACT_522, GO:0009116=GO_REF:0000019, GO:0046654=GO_REF:0000019, GO:0009259=GO_REF:0000019, GO:0006189=GO_REF:0000041, GO:0006164=GO_REF:0000002} P31939 Bifunctional purine biosynthesis protein PURH protein 20130213 {GO:0009168=TAS, GO:0021987=IEA, GO:0003360=IEA, GO:0003937=TAS, GO:0031100=IEA, GO:0055086=TAS, GO:0021549=IEA, GO:0044281=TAS, GO:0042803=IPI, GO:0005829=TAS, GO:0005739=IEA, GO:0004643=TAS, GO:0006139=TAS, GO:0046452=IEA, GO:0010035=IEA, GO:0006144=TAS, GO:0009116=IEA, GO:0046654=IEA, GO:0009259=IEA, GO:0006189=IEA, GO:0006164=IEA} 'de novo' IMP biosynthetic process, brainstem development, cerebellum development, cerebral cortex development, dihydrofolate metabolic process, nucleobase-containing compound metabolic process, nucleobase-containing small molecule metabolic process, nucleoside metabolic process, organ regeneration, purine nucleobase metabolic process, purine nucleotide biosynthetic process, purine ribonucleoside monophosphate biosynthetic process, response to inorganic substance, ribonucleotide metabolic process, small molecule metabolic process, tetrahydrofolate biosynthetic process cytosol, mitochondrion IMP cyclohydrolase activity, phosphoribosylaminoimidazolecarboxamide formyltransferase activity, protein homodimerization activity Human ATL1 GOC UniProtKB {GO:0005515=PMID:19665976, GO:0008219=GO_REF:0000037, GO:0030424=GO_REF:0000039, GO:0005794=GO_REF:0000024, GO:0005783=PMID:19665976, GO:0003924=PMID:14506257, GO:0007409=GO_REF:0000024, GO:0005525=GO_REF:0000024, GO:0042802=PMID:14506257, GO:0006184=PMID:14506257, GO:0000137=GO_REF:0000024, GO:0000139=GO_REF:0000039, GO:0005789=GO_REF:0000024, GO:0051260=PMID:14506257, GO:0016021=PMID:14506257, GO:0007029=PMID:19665976} Q8WXF7 Atlastin-1 protein 20130413 {GO:0005515=IPI, GO:0008219=IEA, GO:0030424=IEA, GO:0005794=ISS, GO:0005783=IDA, GO:0003924=IDA, GO:0007409=ISS, GO:0005525=ISS, GO:0042802=IDA, GO:0006184=IDA, GO:0000137=ISS, GO:0000139=IEA, GO:0005789=ISS, GO:0051260=IDA, GO:0016021=IDA, GO:0007029=IDA} GTP catabolic process, axonogenesis, cell death, endoplasmic reticulum organization, protein homooligomerization Golgi apparatus, Golgi cis cisterna, Golgi membrane, axon, endoplasmic reticulum, endoplasmic reticulum membrane, integral to membrane GTP binding, GTPase activity, identical protein binding, protein binding Human ATL2 GOC UniProtKB {GO:0006184=PMID:18270207, GO:0006888=PMID:18270207, GO:0005515=PMID:19665976, GO:0005783=PMID:18270207, GO:0007030=PMID:18270207, GO:0005789=GO_REF:0000039, GO:0003924=PMID:18270207, GO:0051260=PMID:18270207, GO:0016021=PMID:18270207, GO:0005525=GO_REF:0000037, GO:0007029=PMID:19665976, GO:0042802=PMID:18270207} Q8NHH9 Atlastin-2 protein 20130413 {GO:0006184=NAS, GO:0006888=IMP, GO:0005515=IPI, GO:0005783=IDA, GO:0007030=IMP, GO:0005789=IEA, GO:0003924=NAS, GO:0051260=IDA, GO:0016021=IDA, GO:0005525=IEA, GO:0007029=IMP, GO:0042802=IDA} ER to Golgi vesicle-mediated transport, GTP catabolic process, Golgi organization, endoplasmic reticulum organization, protein homooligomerization endoplasmic reticulum, endoplasmic reticulum membrane, integral to membrane GTP binding, GTPase activity, identical protein binding, protein binding Human ATL3 GOC UniProtKB {GO:0006184=PMID:18270207, GO:0006888=PMID:18270207, GO:0005783=PMID:18270207, GO:0007030=PMID:18270207, GO:0005789=GO_REF:0000039, GO:0003924=PMID:18270207, GO:0051260=PMID:18270207, GO:0016021=PMID:18270207, GO:0005525=GO_REF:0000037, GO:0007029=PMID:19665976, GO:0042802=PMID:18270207} Q6DD88 Atlastin-3 protein 20130413 {GO:0006184=NAS, GO:0006888=IMP, GO:0005783=IDA, GO:0007030=IMP, GO:0005789=IEA, GO:0003924=NAS, GO:0051260=IDA, GO:0016021=IDA, GO:0005525=IEA, GO:0007029=IMP, GO:0042802=IDA} ER to Golgi vesicle-mediated transport, GTP catabolic process, Golgi organization, endoplasmic reticulum organization, protein homooligomerization endoplasmic reticulum, endoplasmic reticulum membrane, integral to membrane GTP binding, GTPase activity, identical protein binding Human ATM GOC UniProtKB {GO:0005515=PMID:20810650, GO:0002331=GO_REF:0000024, GO:0001756=GO_REF:0000019, GO:0004677=PMID:15790808, GO:0051402=GO_REF:0000019, GO:0032403=PMID:15790808, GO:0007507=GO_REF:0000019, GO:0043525=GO_REF:0000019, GO:0046777=PMID:9733515, GO:0018105=PMID:9733515, GO:0016303=PMID:11375976, GO:0046983=PMID:15790808, GO:0007131=PMID:7792600, GO:0006977=Reactome:REACT_1625, GO:0000781=PMID:15149599, GO:0036092=PMID:11375976, GO:0005819=GO_REF:0000019, GO:0030889=PMID:17875758, GO:0035174=GO_REF:0000019, GO:0006281=Reactome:REACT_216, GO:0007420=GO_REF:0000019, GO:0071044=PMID:16086026, GO:0000075=Reactome:REACT_1538, GO:0005654=Reactome:REACT_20543, GO:0000077=GO_REF:0000002, GO:0090399=PMID:15149599, GO:0042159=GO_REF:0000019, GO:0007094=PMID:11943150, GO:0031572=PMID:15149599, GO:0005634=GO_REF:0000019, GO:0071480=PMID:9925639, GO:0006302=Reactome:REACT_2054, GO:0005737=GO_REF:0000019, GO:0000723=GO_REF:0000002, GO:0000724=Reactome:REACT_1874, GO:0010212=PMID:9733515, GO:0051726=GO_REF:0000019, GO:0007050=PMID:15149599, GO:0001666=GO_REF:0000019, GO:0043066=GO_REF:0000019, GO:0043065=PMID:17875758, GO:0008630=GO_REF:0000019, GO:0016572=GO_REF:0000002, GO:0007292=GO_REF:0000019, GO:0003677=GO_REF:0000037, GO:0005524=GO_REF:0000037, GO:0006974=PMID:15790808, GO:0006975=PMID:9733515, GO:0007165=PMID:7792600, GO:0047485=PMID:11375976, GO:0004674=PMID:9733515, GO:0043517=PMID:9733515, GO:0016023=GO_REF:0000039} Q13315 Serine-protein kinase ATM protein 20130413 {GO:0005515=IPI, GO:0002331=ISS, GO:0001756=IEA, GO:0004677=IDA, GO:0051402=IEA, GO:0032403=IDA, GO:0007507=IEA, GO:0043525=IEA, GO:0046777=IDA, GO:0018105=IDA, GO:0016303=IMP, GO:0046983=IDA, GO:0007131=TAS, GO:0006977=TAS, GO:0000781=IDA, GO:0036092=IMP, GO:0005819=IEA, GO:0030889=IMP, GO:0035174=IEA, GO:0006281=TAS, GO:0007420=IEA, GO:0071044=IDA, GO:0000075=TAS, GO:0005654=TAS, GO:0000077=IEA, GO:0090399=IMP, GO:0042159=IEA, GO:0007094=IMP, GO:0031572=IMP, GO:0005634=IEA, GO:0071480=IDA, GO:0006302=TAS, GO:0005737=IEA, GO:0000723=IEA, GO:0000724=TAS, GO:0010212=IDA, GO:0051726=IEA, GO:0007050=IMP, GO:0001666=IEA, GO:0043066=IEA, GO:0043065=IMP, GO:0008630=IEA, GO:0016572=IEA, GO:0007292=IEA, GO:0003677=IEA, GO:0005524=IEA, GO:0006974=IMP, GO:0006975=IDA, GO:0007165=TAS, GO:0047485=IDA, GO:0004674=IDA, GO:0043517=IMP, GO:0016023=IEA} DNA damage checkpoint, DNA damage induced protein phosphorylation, DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest, DNA repair, G2 DNA damage checkpoint, brain development, cell cycle arrest, cell cycle checkpoint, cellular response to gamma radiation, double-strand break repair, double-strand break repair via homologous recombination, female gamete generation, heart development, histone mRNA catabolic process, histone phosphorylation, intrinsic apoptotic signaling pathway in response to DNA damage, lipoprotein catabolic process, mitotic spindle assembly checkpoint, negative regulation of B cell proliferation, negative regulation of apoptotic process, neuron apoptotic process, peptidyl-serine phosphorylation, phosphatidylinositol-3-phosphate biosynthetic process, positive regulation of DNA damage response, signal transduction by p53 class mediator, positive regulation of apoptotic process, positive regulation of neuron apoptotic process, pre-B cell allelic exclusion, protein autophosphorylation, reciprocal meiotic recombination, regulation of cell cycle, replicative senescence, response to DNA damage stimulus, response to hypoxia, response to ionizing radiation, signal transduction, somitogenesis, telomere maintenance chromosome, telomeric region, cytoplasm, cytoplasmic membrane-bounded vesicle, nucleoplasm, nucleus, spindle 1-phosphatidylinositol-3-kinase activity, ATP binding, DNA binding, DNA-dependent protein kinase activity, histone serine kinase activity, protein N-terminus binding, protein binding, protein complex binding, protein dimerization activity, protein serine/threonine kinase activity Human ATMIN UniProtKB UniProtKB {GO:0045502=PMID:22167198, GO:0044212=GO_REF:0000019, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0045893=PMID:22167198, GO:0006974=GO_REF:0000037, GO:0006351=GO_REF:0000037} O43313 ATM interactor protein 20120706 {GO:0045502=IPI, GO:0044212=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0045893=IDA, GO:0006974=IEA, GO:0006351=IEA} positive regulation of transcription, DNA-dependent, response to DNA damage stimulus, transcription, DNA-dependent nucleus dynein binding, transcription regulatory region DNA binding, zinc ion binding Human UniProtKB:P63167 ATN1 IntAct UniProtKB {GO:0005515=PMID:16713569, GO:0048471=GO_REF:0000039, GO:0030054=GO_REF:0000039, GO:0003714=PMID:10973986, GO:0019904=PMID:11984006, GO:0005634=PMID:10085113, GO:0030011=GO_REF:0000019, GO:0000122=PMID:10973986, GO:0007417=PMID:7647802, GO:0051402=PMID:10085113, GO:0016363=PMID:10973986, GO:0006351=GO_REF:0000037, GO:0005737=PMID:7647802, GO:0050827=GO_REF:0000019, GO:0016477=GO_REF:0000019, GO:0009404=GO_REF:0000019} P54259 Atrophin-1 protein 20130415 {GO:0005515=IPI, GO:0048471=IEA, GO:0030054=IEA, GO:0003714=IDA, GO:0019904=IPI, GO:0005634=IDA, GO:0030011=IEA, GO:0000122=IDA, GO:0007417=TAS, GO:0051402=IDA, GO:0016363=IDA, GO:0006351=IEA, GO:0005737=TAS, GO:0050827=IEA, GO:0016477=IEA, GO:0009404=IEA} cell migration, central nervous system development, maintenance of cell polarity, negative regulation of transcription from RNA polymerase II promoter, neuron apoptotic process, toxin metabolic process, transcription, DNA-dependent cell junction, cytoplasm, nuclear matrix, nucleus, perinuclear region of cytoplasm protein binding, protein domain specific binding, toxin receptor binding, transcription corepressor activity Human UniProtKB:Q9P2R6 ATOH1 PINC UniProtKB {GO:0042668=GO_REF:0000019, GO:0003700=PMID:8872459, GO:0021987=GO_REF:0000019, GO:0042472=GO_REF:0000019, GO:0006366=PMID:8872459, GO:0006915=GO_REF:0000019, GO:0005634=GO_REF:0000024, GO:0007417=PMID:8872459, GO:0042667=GO_REF:0000019, GO:0031490=GO_REF:0000019, GO:0043565=GO_REF:0000019, GO:0007411=GO_REF:0000019, GO:0045666=GO_REF:0000024, GO:0045944=GO_REF:0000019, GO:0045609=GO_REF:0000019, GO:0046983=GO_REF:0000002, GO:0001764=GO_REF:0000019} Q92858 Protein atonal homolog 1 protein 20030904 {GO:0042668=IEA, GO:0003700=TAS, GO:0021987=IEA, GO:0042472=IEA, GO:0006366=TAS, GO:0006915=IEA, GO:0005634=ISS, GO:0007417=TAS, GO:0042667=IEA, GO:0031490=IEA, GO:0043565=IEA, GO:0007411=IEA, GO:0045666=ISS, GO:0045944=IEA, GO:0045609=IEA, GO:0046983=IEA, GO:0001764=IEA} apoptotic process, auditory receptor cell fate determination, auditory receptor cell fate specification, axon guidance, central nervous system development, cerebral cortex development, inner ear morphogenesis, neuron migration, positive regulation of auditory receptor cell differentiation, positive regulation of neuron differentiation, positive regulation of transcription from RNA polymerase II promoter, transcription from RNA polymerase II promoter nucleus chromatin DNA binding, protein dimerization activity, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity Human ATOH8 UniProtKB UniProtKB {GO:0006355=GO_REF:0000037, GO:0046983=GO_REF:0000002, GO:0005634=GO_REF:0000039, GO:0003677=GO_REF:0000037, GO:0030154=GO_REF:0000037, GO:0006351=GO_REF:0000037, GO:0007399=GO_REF:0000037} Q96SQ7 Protein atonal homolog 8 protein 20130413 {GO:0006355=IEA, GO:0046983=IEA, GO:0005634=IEA, GO:0003677=IEA, GO:0030154=IEA, GO:0006351=IEA, GO:0007399=IEA} cell differentiation, nervous system development, regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus DNA binding, protein dimerization activity Human UniProtKB-SubCell:SL-0191 ATOX1 UniProtKB UniProtKB {GO:0032767=PMID:10497213, GO:0006878=GO_REF:0000019, GO:0005507=PMID:12029094, GO:0016531=PMID:12029094, GO:0016530=PMID:15670166, GO:0006979=GO_REF:0000019, GO:0046872=GO_REF:0000002, GO:0030001=GO_REF:0000002, GO:0006825=PMID:15670166, GO:0005829=PMID:12029094} O00244 Copper transport protein ATOX1 protein 20061212 {GO:0032767=IPI, GO:0006878=IEA, GO:0005507=IDA, GO:0016531=IDA, GO:0016530=TAS, GO:0006979=IEA, GO:0046872=IEA, GO:0030001=IEA, GO:0006825=TAS, GO:0005829=TAS} cellular copper ion homeostasis, copper ion transport, metal ion transport, response to oxidative stress cytosol copper chaperone activity, copper ion binding, copper-dependent protein binding, metal ion binding, metallochaperone activity Human UniProtKB:Q04656 ATP10D Reactome UniProtKB {GO:0005515=PMID:21914794, GO:0000287=PMID:12532265, GO:0005886=Reactome:REACT_115892, GO:0005783=PMID:21914794, GO:0005524=PMID:12532265, GO:0055085=Reactome:REACT_15518, GO:0045332=PMID:21914794, GO:0019829=GO_REF:0000002, GO:0034220=Reactome:REACT_25300, GO:0004012=PMID:12532265, GO:0005789=GO_REF:0000039, GO:0016021=PMID:12532265, GO:0006812=PMID:12532265} Q9P241 Probable phospholipid-transporting ATPase VD protein 20130301 {GO:0005515=IPI, GO:0000287=NAS, GO:0005886=TAS, GO:0005783=IDA, GO:0005524=NAS, GO:0055085=TAS, GO:0045332=NAS, GO:0019829=IEA, GO:0034220=TAS, GO:0004012=NAS, GO:0005789=IEA, GO:0016021=NAS, GO:0006812=NAS} cation transport, ion transmembrane transport, phospholipid translocation, transmembrane transport endoplasmic reticulum, endoplasmic reticulum membrane, integral to membrane, plasma membrane ATP binding, cation-transporting ATPase activity, magnesium ion binding, phospholipid-translocating ATPase activity, protein binding Human ATP11A UniProtKB UniProtKB {GO:0005515=PMID:21914794, GO:0019829=GO_REF:0000002, GO:0000287=GO_REF:0000002, GO:0005886=GO_REF:0000039, GO:0005783=PMID:21914794, GO:0004012=GO_REF:0000003, GO:0016021=GO_REF:0000037, GO:0055037=PMID:21914794, GO:0005524=GO_REF:0000037, GO:0045332=PMID:21914794, GO:0005769=GO_REF:0000039} P98196 Probable phospholipid-transporting ATPase IH protein 20110922 {GO:0005515=IPI, GO:0019829=IEA, GO:0000287=IEA, GO:0005886=IEA, GO:0005783=IDA, GO:0004012=IEA, GO:0016021=IEA, GO:0055037=IDA, GO:0005524=IEA, GO:0045332=NAS, GO:0005769=IEA} phospholipid translocation early endosome, endoplasmic reticulum, integral to membrane, plasma membrane, recycling endosome ATP binding, cation-transporting ATPase activity, magnesium ion binding, phospholipid-translocating ATPase activity, protein binding Human ATP11B Reactome UniProtKB {GO:0005515=PMID:21914794, GO:0000287=GO_REF:0000002, GO:0005886=Reactome:REACT_115892, GO:0005783=PMID:21914794, GO:0015075=PMID:11790799, GO:0005637=PMID:11790799, GO:0055085=Reactome:REACT_15518, GO:0005524=GO_REF:0000037, GO:0045332=PMID:21914794, GO:0019829=GO_REF:0000002, GO:0034220=Reactome:REACT_25300, GO:0004012=PMID:11015572, GO:0016021=GO_REF:0000037, GO:0015917=PMID:11015572, GO:0055037=PMID:21914794, GO:0055038=GO_REF:0000039, GO:0005769=GO_REF:0000039, GO:0006811=PMID:11790799} Q9Y2G3 Probable phospholipid-transporting ATPase IF protein 20130301 {GO:0005515=IPI, GO:0000287=IEA, GO:0005886=TAS, GO:0005783=IDA, GO:0015075=NAS, GO:0005637=NAS, GO:0055085=TAS, GO:0005524=IEA, GO:0045332=NAS, GO:0019829=IEA, GO:0034220=TAS, GO:0004012=TAS, GO:0016021=IEA, GO:0015917=TAS, GO:0055037=IDA, GO:0055038=IEA, GO:0005769=IEA, GO:0006811=NAS} aminophospholipid transport, ion transmembrane transport, ion transport, phospholipid translocation, transmembrane transport early endosome, endoplasmic reticulum, integral to membrane, nuclear inner membrane, plasma membrane, recycling endosome, recycling endosome membrane ATP binding, cation-transporting ATPase activity, ion transmembrane transporter activity, magnesium ion binding, phospholipid-translocating ATPase activity, protein binding Human ATP11C Reactome UniProtKB {GO:0005515=PMID:21914794, GO:0019829=GO_REF:0000002, GO:0034220=Reactome:REACT_25300, GO:0000287=GO_REF:0000002, GO:0005886=Reactome:REACT_115892, GO:0005783=PMID:21914794, GO:0004012=GO_REF:0000003, GO:0005789=GO_REF:0000039, GO:0016021=GO_REF:0000037, GO:0055085=Reactome:REACT_15518, GO:0005524=GO_REF:0000037, GO:0045332=PMID:21914794} Q8NB49 Probable phospholipid-transporting ATPase IG protein 20130301 {GO:0005515=IPI, GO:0019829=IEA, GO:0034220=TAS, GO:0000287=IEA, GO:0005886=TAS, GO:0005783=IDA, GO:0004012=IEA, GO:0005789=IEA, GO:0016021=IEA, GO:0055085=TAS, GO:0005524=IEA, GO:0045332=NAS} ion transmembrane transport, phospholipid translocation, transmembrane transport endoplasmic reticulum, endoplasmic reticulum membrane, integral to membrane, plasma membrane ATP binding, cation-transporting ATPase activity, magnesium ion binding, phospholipid-translocating ATPase activity, protein binding Human ATP12A Reactome UniProtKB {GO:0016323=GO_REF:0000019, GO:0006754=GO_REF:0000002, GO:0034220=Reactome:REACT_25300, GO:0005886=Reactome:REACT_25173, GO:0005889=PMID:8838794, GO:0055075=GO_REF:0000019, GO:0008900=GO_REF:0000003, GO:0055085=Reactome:REACT_15518, GO:0005524=GO_REF:0000037, GO:0006885=GO_REF:0000019, GO:0046872=GO_REF:0000037} P54707 Potassium-transporting ATPase alpha chain 2 protein 20130301 {GO:0016323=IEA, GO:0006754=IEA, GO:0034220=TAS, GO:0005886=TAS, GO:0005889=TAS, GO:0055075=IEA, GO:0008900=IEA, GO:0055085=TAS, GO:0005524=IEA, GO:0006885=IEA, GO:0046872=IEA} ATP biosynthetic process, ion transmembrane transport, potassium ion homeostasis, regulation of pH, transmembrane transport basolateral plasma membrane, hydrogen:potassium-exchanging ATPase complex, plasma membrane ATP binding, hydrogen:potassium-exchanging ATPase activity, metal ion binding Human ATP13A1 BHF-UCL UniProtKB {GO:0019829=GO_REF:0000002, GO:0003674=GO_REF:0000015, GO:0008150=GO_REF:0000015, GO:0005575=GO_REF:0000015, GO:0016021=GO_REF:0000037, GO:0005524=GO_REF:0000037, GO:0046872=GO_REF:0000037} Q9HD20 Probable cation-transporting ATPase 13A1 protein 20090331 {GO:0019829=IEA, GO:0003674=ND, GO:0008150=ND, GO:0005575=ND, GO:0016021=IEA, GO:0005524=IEA, GO:0046872=IEA} biological_process cellular_component, integral to membrane ATP binding, cation-transporting ATPase activity, metal ion binding, molecular_function Human ATP13A2 IntAct UniProtKB {GO:0005515=PMID:22645275, GO:0019829=GO_REF:0000002, GO:0000166=GO_REF:0000002, GO:0016021=GO_REF:0000037, GO:0005764=PMID:21542062, GO:0005524=GO_REF:0000037, GO:0046872=GO_REF:0000037} Q9NQ11 Probable cation-transporting ATPase 13A2 protein 20130415 {GO:0005515=IPI, GO:0019829=IEA, GO:0000166=IEA, GO:0016021=IEA, GO:0005764=IDA, GO:0005524=IEA, GO:0046872=IEA} integral to membrane, lysosome ATP binding, cation-transporting ATPase activity, metal ion binding, nucleotide binding, protein binding Human UniProtKB:Q9UBN7 ATP13A3 UniProtKB UniProtKB {GO:0019829=GO_REF:0000002, GO:0016021=GO_REF:0000037, GO:0005524=GO_REF:0000037, GO:0046872=GO_REF:0000037} Q9H7F0 Probable cation-transporting ATPase 13A3 protein 20130413 {GO:0019829=IEA, GO:0016021=IEA, GO:0005524=IEA, GO:0046872=IEA} integral to membrane ATP binding, cation-transporting ATPase activity, metal ion binding Human UniProtKB-KW:KW-0479 ATP13A4 UniProtKB UniProtKB {GO:0019829=GO_REF:0000002, GO:0016021=GO_REF:0000037, GO:0005524=GO_REF:0000037, GO:0046872=GO_REF:0000037} Q4VNC1 Probable cation-transporting ATPase 13A4 protein 20130413 {GO:0019829=IEA, GO:0016021=IEA, GO:0005524=IEA, GO:0046872=IEA} integral to membrane ATP binding, cation-transporting ATPase activity, metal ion binding Human UniProtKB-KW:KW-0479 ATP1A1 InterPro UniProtKB {GO:0005515=PMID:11027149, GO:0005886=Reactome:REACT_25287, GO:0005783=GO_REF:0000019, GO:0003869=GO_REF:0000019, GO:0051087=GO_REF:0000019, GO:0031402=GO_REF:0000019, GO:0046872=GO_REF:0000037, GO:0016323=GO_REF:0000019, GO:0006754=GO_REF:0000002, GO:0034220=Reactome:REACT_25300, GO:0045989=GO_REF:0000019, GO:0045822=GO_REF:0000019, GO:0086004=GO_REF:0000019, GO:0045823=GO_REF:0000019, GO:0005391=GO_REF:0000019, GO:0042470=GO_REF:0000039, GO:0005794=GO_REF:0000019, GO:0019901=GO_REF:0000019, GO:0042493=GO_REF:0000019, GO:0019904=GO_REF:0000019, GO:0030506=GO_REF:0000019, GO:0010107=GO_REF:0000019, GO:0030315=GO_REF:0000019, GO:0030955=GO_REF:0000019, GO:0005890=GO_REF:0000019, GO:0055085=Reactome:REACT_15518, GO:0005524=GO_REF:0000019, GO:0019829=GO_REF:0000002, GO:0060081=GO_REF:0000019, GO:0016020=PMID:1975705, GO:0043531=GO_REF:0000019, GO:0002026=GO_REF:0000019, GO:0005901=GO_REF:0000019, GO:0002028=GO_REF:0000019, GO:0008217=GO_REF:0000019, GO:0031947=GO_REF:0000019, GO:0016021=GO_REF:0000002, GO:0071260=GO_REF:0000019, GO:0005768=GO_REF:0000019, GO:0043548=GO_REF:0000019} Q5TC05 Sodium/potassium-transporting ATPase subunit alpha-1 protein 20130413 {GO:0005515=IPI, GO:0005886=TAS, GO:0005783=IEA, GO:0003869=IEA, GO:0051087=IEA, GO:0031402=IEA, GO:0046872=IEA, GO:0016323=IEA, GO:0006754=IEA, GO:0034220=TAS, GO:0045989=IEA, GO:0045822=IEA, GO:0086004=IEA, GO:0045823=IEA, GO:0005391=IEA, GO:0042470=IEA, GO:0005794=IEA, GO:0019901=IEA, GO:0042493=IEA, GO:0019904=IEA, GO:0030506=IEA, GO:0010107=IEA, GO:0030315=IEA, GO:0030955=IEA, GO:0005890=IEA, GO:0055085=TAS, GO:0005524=IEA, GO:0019829=IEA, GO:0060081=IEA, GO:0016020=TAS, GO:0043531=IEA, GO:0002026=IEA, GO:0005901=IEA, GO:0002028=IEA, GO:0008217=IEA, GO:0031947=IEA, GO:0016021=IEA, GO:0071260=IEA, GO:0005768=IEA, GO:0043548=IEA} ATP biosynthetic process, cellular response to mechanical stimulus, ion transmembrane transport, membrane hyperpolarization, negative regulation of glucocorticoid biosynthetic process, negative regulation of heart contraction, positive regulation of heart contraction, positive regulation of striated muscle contraction, potassium ion import, regulation of blood pressure, regulation of cardiac muscle cell contraction, regulation of sodium ion transport, regulation of the force of heart contraction, response to drug, transmembrane transport Golgi apparatus, T-tubule, basolateral plasma membrane, caveola, endoplasmic reticulum, endosome, integral to membrane, melanosome, membrane, plasma membrane, sodium:potassium-exchanging ATPase complex 4-nitrophenylphosphatase activity, ADP binding, ATP binding, ankyrin binding, cation-transporting ATPase activity, chaperone binding, metal ion binding, phosphatidylinositol 3-kinase binding, potassium ion binding, protein binding, protein domain specific binding, protein kinase binding, sodium ion binding, sodium:potassium-exchanging ATPase activity Human InterPro:IPR001757 ATP1A2 Reactome UniProtKB {GO:0008344=GO_REF:0000019, GO:0005886=Reactome:REACT_25287, GO:0015077=GO_REF:0000002, GO:0006942=PMID:10642400, GO:0045202=GO_REF:0000019, GO:0006940=GO_REF:0000019, GO:0046872=GO_REF:0000037, GO:0019229=GO_REF:0000019, GO:0040011=GO_REF:0000019, GO:0005737=PMID:12539047, GO:0002087=GO_REF:0000019, GO:0006754=GO_REF:0000002, GO:0034220=Reactome:REACT_25300, GO:0043197=GO_REF:0000019, GO:0045988=GO_REF:0000019, GO:0006814=PMID:10642400, GO:0006813=PMID:10642400, GO:0045822=GO_REF:0000019, GO:0086004=GO_REF:0000019, GO:0005391=PMID:12539047, GO:0051481=GO_REF:0000019, GO:0030315=GO_REF:0000019, GO:0005890=PMID:12539047, GO:0055085=Reactome:REACT_15518, GO:0005524=GO_REF:0000019, GO:0019829=GO_REF:0000002, GO:0002026=GO_REF:0000019, GO:0005901=GO_REF:0000019, GO:0008542=GO_REF:0000019, GO:0001504=GO_REF:0000019, GO:0008217=GO_REF:0000019, GO:0015991=GO_REF:0000019, GO:0016021=GO_REF:0000038, GO:0071260=GO_REF:0000019, GO:0005768=GO_REF:0000019, GO:0035094=GO_REF:0000019} P50993 Sodium/potassium-transporting ATPase subunit alpha-2 protein 20130301 {GO:0008344=IEA, GO:0005886=TAS, GO:0015077=IEA, GO:0006942=NAS, GO:0045202=IEA, GO:0006940=IEA, GO:0046872=IEA, GO:0019229=IEA, GO:0040011=IEA, GO:0005737=IDA, GO:0002087=IEA, GO:0006754=IEA, GO:0034220=TAS, GO:0043197=IEA, GO:0045988=IEA, GO:0006814=NAS, GO:0006813=NAS, GO:0045822=IEA, GO:0086004=IEA, GO:0005391=IMP, GO:0051481=IEA, GO:0030315=IEA, GO:0005890=IC, GO:0055085=TAS, GO:0005524=IEA, GO:0019829=IEA, GO:0002026=IEA, GO:0005901=IEA, GO:0008542=IEA, GO:0001504=IEA, GO:0008217=IEA, GO:0015991=IEA, GO:0016021=IEA, GO:0071260=IEA, GO:0005768=IEA, GO:0035094=IEA} ATP biosynthetic process, ATP hydrolysis coupled proton transport, adult locomotory behavior, cellular response to mechanical stimulus, ion transmembrane transport, locomotion, negative regulation of heart contraction, negative regulation of striated muscle contraction, neurotransmitter uptake, potassium ion transport, reduction of cytosolic calcium ion concentration, regulation of blood pressure, regulation of cardiac muscle cell contraction, regulation of respiratory gaseous exchange by neurological system process, regulation of smooth muscle contraction, regulation of striated muscle contraction, regulation of the force of heart contraction, regulation of vasoconstriction, response to nicotine, sodium ion transport, transmembrane transport, visual learning T-tubule, caveola, cytoplasm, dendritic spine, endosome, integral to membrane, plasma membrane, sodium:potassium-exchanging ATPase complex, synapse ATP binding, cation-transporting ATPase activity, metal ion binding, monovalent inorganic cation transmembrane transporter activity, sodium:potassium-exchanging ATPase activity Human ATP1A3 Reactome UniProtKB {GO:0008344=GO_REF:0000019, GO:0030424=GO_REF:0000019, GO:0005794=PMID:15260953, GO:0005886=Reactome:REACT_25287, GO:0005783=PMID:15260953, GO:0042493=GO_REF:0000019, GO:0015077=GO_REF:0000002, GO:0045202=GO_REF:0000024, GO:0005634=GO_REF:0000019, GO:0005890=PMID:15260953, GO:0055085=Reactome:REACT_15518, GO:0005524=PMID:15260953, GO:0046872=GO_REF:0000037, GO:0019829=GO_REF:0000002, GO:0006754=GO_REF:0000002, GO:0035235=GO_REF:0000019, GO:0034220=Reactome:REACT_25300, GO:0000166=GO_REF:0000002, GO:0043209=GO_REF:0000019, GO:0008542=GO_REF:0000019, GO:0007613=GO_REF:0000019, GO:0016021=PMID:15260953, GO:0005391=PMID:15260953} P13637 Sodium/potassium-transporting ATPase subunit alpha-3 protein 20130301 {GO:0008344=IEA, GO:0030424=IEA, GO:0005794=IDA, GO:0005886=TAS, GO:0005783=IDA, GO:0042493=IEA, GO:0015077=IEA, GO:0045202=ISS, GO:0005634=IEA, GO:0005890=IC, GO:0055085=TAS, GO:0005524=NAS, GO:0046872=IEA, GO:0019829=IEA, GO:0006754=IEA, GO:0035235=IEA, GO:0034220=TAS, GO:0000166=IEA, GO:0043209=IEA, GO:0008542=IEA, GO:0007613=IEA, GO:0016021=NAS, GO:0005391=IMP} ATP biosynthetic process, adult locomotory behavior, ion transmembrane transport, ionotropic glutamate receptor signaling pathway, memory, response to drug, transmembrane transport, visual learning Golgi apparatus, axon, endoplasmic reticulum, integral to membrane, myelin sheath, nucleus, plasma membrane, sodium:potassium-exchanging ATPase complex, synapse ATP binding, cation-transporting ATPase activity, metal ion binding, monovalent inorganic cation transmembrane transporter activity, nucleotide binding, sodium:potassium-exchanging ATPase activity Human ATP1A4 Reactome UniProtKB {GO:0005886=Reactome:REACT_25287, GO:0007283=GO_REF:0000019, GO:0030317=PMID:12112599, GO:0005890=PMID:7809153, GO:0055085=Reactome:REACT_15518, GO:0005524=GO_REF:0000037, GO:0046872=GO_REF:0000037, GO:0019829=GO_REF:0000002, GO:0009566=GO_REF:0000019, GO:0006754=GO_REF:0000002, GO:0034220=Reactome:REACT_25300, GO:0005887=PMID:7809153, GO:0030641=PMID:12112599, GO:0042391=GO_REF:0000019, GO:0015991=PMID:7809153, GO:0016021=GO_REF:0000038, GO:0006814=PMID:7809153, GO:0006813=PMID:7809153, GO:0005391=PMID:7809153} Q13733 Sodium/potassium-transporting ATPase subunit alpha-4 protein 20130301 {GO:0005886=TAS, GO:0007283=IEA, GO:0030317=IDA, GO:0005890=TAS, GO:0055085=TAS, GO:0005524=IEA, GO:0046872=IEA, GO:0019829=IEA, GO:0009566=IEA, GO:0006754=IEA, GO:0034220=TAS, GO:0005887=NAS, GO:0030641=IDA, GO:0042391=IEA, GO:0015991=TAS, GO:0016021=IEA, GO:0006814=TAS, GO:0006813=TAS, GO:0005391=TAS} ATP biosynthetic process, ATP hydrolysis coupled proton transport, fertilization, ion transmembrane transport, potassium ion transport, regulation of cellular pH, regulation of membrane potential, sodium ion transport, sperm motility, spermatogenesis, transmembrane transport integral to membrane, integral to plasma membrane, plasma membrane, sodium:potassium-exchanging ATPase complex ATP binding, cation-transporting ATPase activity, metal ion binding, sodium:potassium-exchanging ATPase activity Human ATP1B1 BHF-UCL UniProtKB {GO:0005515=PMID:17947299, GO:0001666=GO_REF:0000019, GO:0005886=Reactome:REACT_25287, GO:0050900=Reactome:REACT_12051, GO:0005890=GO_REF:0000019, GO:0055085=Reactome:REACT_15518, GO:0016323=GO_REF:0000019, GO:0016324=GO_REF:0000019, GO:0034220=Reactome:REACT_25300, GO:0007596=Reactome:REACT_604, GO:0005901=GO_REF:0000019, GO:0006810=PMID:2559024, GO:0006814=GO_REF:0000002, GO:0007155=GO_REF:0000037, GO:0006813=GO_REF:0000002, GO:0005391=GO_REF:0000019} P05026 Sodium/potassium-transporting ATPase subunit beta-1 protein 20080507 {GO:0005515=IPI, GO:0001666=IEA, GO:0005886=TAS, GO:0050900=TAS, GO:0005890=IEA, GO:0055085=TAS, GO:0016323=IEA, GO:0016324=IEA, GO:0034220=TAS, GO:0007596=TAS, GO:0005901=IEA, GO:0006810=TAS, GO:0006814=IEA, GO:0007155=IEA, GO:0006813=IEA, GO:0005391=IEA} blood coagulation, cell adhesion, ion transmembrane transport, leukocyte migration, potassium ion transport, response to hypoxia, sodium ion transport, transmembrane transport, transport apical plasma membrane, basolateral plasma membrane, caveola, plasma membrane, sodium:potassium-exchanging ATPase complex protein binding, sodium:potassium-exchanging ATPase activity Human UniProtKB:O76024 ATP1B2 Reactome UniProtKB {GO:0005515=PMID:11027149, GO:0005886=Reactome:REACT_25287, GO:0005890=GO_REF:0000002, GO:0050900=Reactome:REACT_12051, GO:0055085=Reactome:REACT_15518, GO:0005737=GO_REF:0000019, GO:0034220=Reactome:REACT_25300, GO:0007596=Reactome:REACT_604, GO:0006810=PMID:2538450, GO:0006814=GO_REF:0000002, GO:0007155=GO_REF:0000037, GO:0006813=GO_REF:0000002, GO:0005391=PMID:2538450} P14415 Sodium/potassium-transporting ATPase subunit beta-2 protein 20130301 {GO:0005515=IPI, GO:0005886=TAS, GO:0005890=IEA, GO:0050900=TAS, GO:0055085=TAS, GO:0005737=IEA, GO:0034220=TAS, GO:0007596=TAS, GO:0006810=TAS, GO:0006814=IEA, GO:0007155=IEA, GO:0006813=IEA, GO:0005391=TAS} blood coagulation, cell adhesion, ion transmembrane transport, leukocyte migration, potassium ion transport, sodium ion transport, transmembrane transport, transport cytoplasm, plasma membrane, sodium:potassium-exchanging ATPase complex protein binding, sodium:potassium-exchanging ATPase activity Human ATP1B3 Reactome UniProtKB {GO:0042470=GO_REF:0000039, GO:0005886=Reactome:REACT_25287, GO:0005890=GO_REF:0000019, GO:0050900=Reactome:REACT_12051, GO:0055085=Reactome:REACT_15518, GO:0005737=GO_REF:0000019, GO:0034220=Reactome:REACT_25300, GO:0007596=Reactome:REACT_604, GO:0005901=GO_REF:0000019, GO:0006810=PMID:8798450, GO:0006814=GO_REF:0000002, GO:0006813=GO_REF:0000002, GO:0005391=GO_REF:0000019} P54709 Sodium/potassium-transporting ATPase subunit beta-3 protein 20130301 {GO:0042470=IEA, GO:0005886=TAS, GO:0005890=IEA, GO:0050900=TAS, GO:0055085=TAS, GO:0005737=IEA, GO:0034220=TAS, GO:0007596=TAS, GO:0005901=IEA, GO:0006810=TAS, GO:0006814=IEA, GO:0006813=IEA, GO:0005391=IEA} blood coagulation, ion transmembrane transport, leukocyte migration, potassium ion transport, sodium ion transport, transmembrane transport, transport caveola, cytoplasm, melanosome, plasma membrane, sodium:potassium-exchanging ATPase complex sodium:potassium-exchanging ATPase activity Human ATP2A1 BHF-UCL UniProtKB {GO:0005515=PMID:9295312, GO:0034976=PMID:19061639, GO:0046872=GO_REF:0000002, GO:0042803=PMID:11402072, GO:0034220=Reactome:REACT_25300, GO:0008637=PMID:19061639, GO:0000166=GO_REF:0000002, GO:0051561=PMID:19061639, GO:0006816=PMID:9405806, GO:0031095=Reactome:REACT_23784, GO:0090076=PMID:8841193, GO:0005509=PMID:9405806, GO:0033017=PMID:8040329, GO:0034704=PMID:11402072, GO:0005524=GO_REF:0000037, GO:0055085=Reactome:REACT_15518, GO:0019829=GO_REF:0000002, GO:0005388=PMID:8729696, GO:0070509=PMID:8040329, GO:0016529=PMID:8841193, GO:0007596=Reactome:REACT_604, GO:0031448=PMID:12479237, GO:0070059=PMID:19061639, GO:0005789=Reactome:REACT_25316, GO:0051659=PMID:19061639, GO:0016021=PMID:9405806, GO:0032470=PMID:11402072, GO:0032471=PMID:11402072} O14983 Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 protein 20100524 {GO:0005515=IPI, GO:0034976=IMP, GO:0046872=IEA, GO:0042803=IPI, GO:0034220=TAS, GO:0008637=IMP, GO:0000166=IEA, GO:0051561=IMP, GO:0006816=IMP, GO:0031095=TAS, GO:0090076=IDA, GO:0005509=IMP, GO:0033017=IC, GO:0034704=IC, GO:0005524=IEA, GO:0055085=TAS, GO:0019829=IEA, GO:0005388=IDA, GO:0070509=IMP, GO:0016529=NAS, GO:0007596=TAS, GO:0031448=IDA, GO:0070059=IMP, GO:0005789=TAS, GO:0051659=IMP, GO:0016021=NAS, GO:0032470=IMP, GO:0032471=IMP} apoptotic mitochondrial changes, blood coagulation, calcium ion import, calcium ion transport, elevation of endoplasmic reticulum calcium ion concentration, elevation of mitochondrial calcium ion concentration, intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress, ion transmembrane transport, maintenance of mitochondrion location, positive regulation of fast-twitch skeletal muscle fiber contraction, reduction of endoplasmic reticulum calcium ion concentration, relaxation of skeletal muscle, response to endoplasmic reticulum stress, transmembrane transport calcium channel complex, endoplasmic reticulum membrane, integral to membrane, platelet dense tubular network membrane, sarcoplasmic reticulum, sarcoplasmic reticulum membrane ATP binding, calcium ion binding, calcium-transporting ATPase activity, cation-transporting ATPase activity, metal ion binding, nucleotide binding, protein binding, protein homodimerization activity Human ATP2A2 BHF-UCL UniProtKB {GO:0006984=GO_REF:0000019, GO:0070296=PMID:19095005, GO:0046872=GO_REF:0000037, GO:0043231=PMID:2844796, GO:0034220=Reactome:REACT_25300, GO:0000166=GO_REF:0000002, GO:0006810=PMID:2844796, GO:0007155=PMID:10080178, GO:0031095=Reactome:REACT_23784, GO:0045822=GO_REF:0000019, GO:0006874=GO_REF:0000019, GO:0033017=PMID:19095005, GO:0005524=GO_REF:0000037, GO:0055085=Reactome:REACT_15518, GO:0019829=GO_REF:0000002, GO:0044548=PMID:12804600, GO:0005388=PMID:2844796, GO:0016529=PMID:12804600, GO:0008544=PMID:10080178, GO:0016020=PMID:2844796, GO:0002026=GO_REF:0000019, GO:0005887=PMID:2844796, GO:0007596=Reactome:REACT_604, GO:0086039=PMID:22679139, GO:0005789=Reactome:REACT_25316, GO:0055119=PMID:22679139, GO:0010460=PMID:22679139, GO:0016021=GO_REF:0000002, GO:0086036=PMID:22679139} P16615 Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 protein 20130206 {GO:0006984=IEA, GO:0070296=TAS, GO:0046872=IEA, GO:0043231=TAS, GO:0034220=TAS, GO:0000166=IEA, GO:0006810=TAS, GO:0007155=TAS, GO:0031095=TAS, GO:0045822=IEA, GO:0006874=IEA, GO:0033017=TAS, GO:0005524=IEA, GO:0055085=TAS, GO:0019829=IEA, GO:0044548=IPI, GO:0005388=TAS, GO:0016529=IDA, GO:0008544=TAS, GO:0016020=TAS, GO:0002026=IEA, GO:0005887=TAS, GO:0007596=TAS, GO:0086039=TAS, GO:0005789=TAS, GO:0055119=TAS, GO:0010460=TAS, GO:0016021=IEA, GO:0086036=TAS} ER-nucleus signaling pathway, blood coagulation, cell adhesion, cellular calcium ion homeostasis, epidermis development, ion transmembrane transport, negative regulation of heart contraction, positive regulation of heart rate, regulation of cardiac muscle cell membrane potential, regulation of the force of heart contraction, relaxation of cardiac muscle, sarcoplasmic reticulum calcium ion transport, transmembrane transport, transport endoplasmic reticulum membrane, integral to membrane, integral to plasma membrane, intracellular membrane-bounded organelle, membrane, platelet dense tubular network membrane, sarcoplasmic reticulum, sarcoplasmic reticulum membrane ATP binding, S100 protein binding, calcium-transporting ATPase activity, calcium-transporting ATPase activity involved in regulation of cardiac muscle cell membrane potential, cation-transporting ATPase activity, metal ion binding, nucleotide binding Human ATP2A3 Reactome UniProtKB {GO:0031965=GO_REF:0000039, GO:0005783=PMID:8809064, GO:0033017=GO_REF:0000039, GO:0055085=Reactome:REACT_15518, GO:0005524=GO_REF:0000037, GO:0046872=GO_REF:0000037, GO:0019829=GO_REF:0000002, GO:0005388=GO_REF:0000003, GO:0034220=Reactome:REACT_25300, GO:0016529=PMID:8809064, GO:0007596=Reactome:REACT_604, GO:0006810=PMID:8809064, GO:0005789=Reactome:REACT_25316, GO:0006816=PMID:8809064, GO:0016021=GO_REF:0000037, GO:0031095=Reactome:REACT_23784} Q93084 Sarcoplasmic/endoplasmic reticulum calcium ATPase 3 protein 20130301 {GO:0031965=IEA, GO:0005783=IDA, GO:0033017=IEA, GO:0055085=TAS, GO:0005524=IEA, GO:0046872=IEA, GO:0019829=IEA, GO:0005388=IEA, GO:0034220=TAS, GO:0016529=IDA, GO:0007596=TAS, GO:0006810=TAS, GO:0005789=TAS, GO:0006816=TAS, GO:0016021=IEA, GO:0031095=TAS} blood coagulation, calcium ion transport, ion transmembrane transport, transmembrane transport, transport endoplasmic reticulum, endoplasmic reticulum membrane, integral to membrane, nuclear membrane, platelet dense tubular network membrane, sarcoplasmic reticulum, sarcoplasmic reticulum membrane ATP binding, calcium-transporting ATPase activity, cation-transporting ATPase activity, metal ion binding Human ATP2B1 Reactome UniProtKB {GO:0019829=GO_REF:0000002, GO:0005516=GO_REF:0000037, GO:0005388=GO_REF:0000003, GO:0034220=Reactome:REACT_25300, GO:0005886=Reactome:REACT_23956, GO:0007596=Reactome:REACT_604, GO:0005887=PMID:8396145, GO:0006810=PMID:8396145, GO:0016021=GO_REF:0000002, GO:0055085=Reactome:REACT_15518, GO:0005524=GO_REF:0000037, GO:0046872=GO_REF:0000037} P20020 Plasma membrane calcium-transporting ATPase 1 protein 20130301 {GO:0019829=IEA, GO:0005516=IEA, GO:0005388=IEA, GO:0034220=TAS, GO:0005886=TAS, GO:0007596=TAS, GO:0005887=TAS, GO:0006810=TAS, GO:0016021=IEA, GO:0055085=TAS, GO:0005524=IEA, GO:0046872=IEA} blood coagulation, ion transmembrane transport, transmembrane transport, transport integral to membrane, integral to plasma membrane, plasma membrane ATP binding, calcium-transporting ATPase activity, calmodulin binding, cation-transporting ATPase activity, metal ion binding Human ATP2B2 Reactome UniProtKB {GO:0008361=GO_REF:0000019, GO:0005516=GO_REF:0000037, GO:0005886=Reactome:REACT_23956, GO:0005783=GO_REF:0000019, GO:0051928=GO_REF:0000019, GO:0007605=PMID:15829536, GO:0060088=GO_REF:0000019, GO:0046068=GO_REF:0000019, GO:0030899=GO_REF:0000019, GO:0046872=GO_REF:0000037, GO:0021707=GO_REF:0000019, GO:0040011=GO_REF:0000019, GO:0005737=PMID:15765049, GO:0016324=GO_REF:0000019, GO:0034220=Reactome:REACT_25300, GO:0021702=GO_REF:0000019, GO:0048167=GO_REF:0000019, GO:0030182=PMID:11259493, GO:0006810=PMID:1313367, GO:0090102=GO_REF:0000019, GO:0043025=GO_REF:0000019, GO:0050885=GO_REF:0000019, GO:0006816=PMID:17234811, GO:0007626=GO_REF:0000019, GO:0045299=GO_REF:0000019, GO:0006996=GO_REF:0000019, GO:0051480=PMID:17234811, GO:0055085=Reactome:REACT_15518, GO:0005524=GO_REF:0000037, GO:0042428=GO_REF:0000019, GO:0005929=GO_REF:0000019, GO:0005388=PMID:1313367, GO:0007595=GO_REF:0000019, GO:0050808=GO_REF:0000019, GO:0007596=Reactome:REACT_604, GO:0050910=GO_REF:0000019, GO:0016021=GO_REF:0000037} Q01814 Plasma membrane calcium-transporting ATPase 2 protein 20130301 {GO:0008361=IEA, GO:0005516=IEA, GO:0005886=TAS, GO:0005783=IEA, GO:0051928=IEA, GO:0007605=IMP, GO:0060088=IEA, GO:0046068=IEA, GO:0030899=IEA, GO:0046872=IEA, GO:0021707=IEA, GO:0040011=IEA, GO:0005737=IDA, GO:0016324=IEA, GO:0034220=TAS, GO:0021702=IEA, GO:0048167=IEA, GO:0030182=IDA, GO:0006810=NAS, GO:0090102=IEA, GO:0043025=IEA, GO:0050885=IEA, GO:0006816=IMP, GO:0007626=IEA, GO:0045299=IEA, GO:0006996=IEA, GO:0051480=IMP, GO:0055085=TAS, GO:0005524=IEA, GO:0042428=IEA, GO:0005929=IEA, GO:0005388=NAS, GO:0007595=IEA, GO:0050808=IEA, GO:0007596=TAS, GO:0050910=IEA, GO:0016021=IEA} auditory receptor cell stereocilium organization, blood coagulation, cGMP metabolic process, calcium ion transport, cerebellar Purkinje cell differentiation, cerebellar granule cell differentiation, cochlea development, cytosolic calcium ion homeostasis, detection of mechanical stimulus involved in sensory perception of sound, ion transmembrane transport, lactation, locomotion, locomotory behavior, neuromuscular process controlling balance, neuron differentiation, organelle organization, otolith mineralization, positive regulation of calcium ion transport, regulation of cell size, regulation of synaptic plasticity, sensory perception of sound, serotonin metabolic process, synapse organization, transmembrane transport, transport apical plasma membrane, cilium, cytoplasm, endoplasmic reticulum, integral to membrane, neuronal cell body, plasma membrane ATP binding, calcium-dependent ATPase activity, calcium-transporting ATPase activity, calmodulin binding, metal ion binding Human ATP2B3 Reactome UniProtKB {GO:0005388=GO_REF:0000003, GO:0005516=GO_REF:0000037, GO:0034220=Reactome:REACT_25300, GO:0005886=Reactome:REACT_23956, GO:0007596=Reactome:REACT_604, GO:0006810=PMID:8765088, GO:0016021=GO_REF:0000037, GO:0055085=Reactome:REACT_15518, GO:0005524=GO_REF:0000037, GO:0046872=GO_REF:0000037} Q16720 Plasma membrane calcium-transporting ATPase 3 protein 20130301 {GO:0005388=IEA, GO:0005516=IEA, GO:0034220=TAS, GO:0005886=TAS, GO:0007596=TAS, GO:0006810=TAS, GO:0016021=IEA, GO:0055085=TAS, GO:0005524=IEA, GO:0046872=IEA} blood coagulation, ion transmembrane transport, transmembrane transport, transport integral to membrane, plasma membrane ATP binding, calcium-transporting ATPase activity, calmodulin binding, metal ion binding Human ATP2B4 Reactome UniProtKB {GO:0005516=GO_REF:0000037, GO:0005388=GO_REF:0000003, GO:0034220=Reactome:REACT_25300, GO:0005886=Reactome:REACT_23956, GO:0007596=Reactome:REACT_604, GO:0005887=PMID:2137451, GO:0006810=PMID:2137451, GO:0055085=Reactome:REACT_15518, GO:0005524=GO_REF:0000037, GO:0046872=GO_REF:0000037} P23634 Plasma membrane calcium-transporting ATPase 4 protein 20130301 {GO:0005516=IEA, GO:0005388=IEA, GO:0034220=TAS, GO:0005886=TAS, GO:0007596=TAS, GO:0005887=TAS, GO:0006810=TAS, GO:0055085=TAS, GO:0005524=IEA, GO:0046872=IEA} blood coagulation, ion transmembrane transport, transmembrane transport, transport integral to plasma membrane, plasma membrane ATP binding, calcium-transporting ATPase activity, calmodulin binding, metal ion binding Human ATP2C1 GOC UniProtKB {GO:0005802=PMID:14632183, GO:0005794=PMID:11741891, GO:0031532=PMID:14632182, GO:0032468=PMID:14632183, GO:0006874=PMID:12810057, GO:0055085=Reactome:REACT_15518, GO:0005524=GO_REF:0000037, GO:0046872=GO_REF:0000037, GO:0019829=GO_REF:0000002, GO:0016339=PMID:14632182, GO:0007165=PMID:12761501, GO:0005388=PMID:12810057, GO:0034220=Reactome:REACT_25300, GO:0000139=Reactome:REACT_25301, GO:0008544=PMID:10615129, GO:0006816=PMID:12810057, GO:0016021=PMID:10615129, GO:0004871=PMID:12761501, GO:0043123=PMID:12761501, GO:0032472=PMID:14632183} P98194 Calcium-transporting ATPase type 2C member 1 protein 20130413 {GO:0005802=IDA, GO:0005794=IDA, GO:0031532=IMP, GO:0032468=IMP, GO:0006874=IDA, GO:0055085=TAS, GO:0005524=IEA, GO:0046872=IEA, GO:0019829=IEA, GO:0016339=IMP, GO:0007165=IMP, GO:0005388=IDA, GO:0034220=TAS, GO:0000139=TAS, GO:0008544=IMP, GO:0006816=IDA, GO:0016021=NAS, GO:0004871=IMP, GO:0043123=IMP, GO:0032472=IMP} Golgi calcium ion homeostasis, Golgi calcium ion transport, actin cytoskeleton reorganization, calcium ion transport, calcium-dependent cell-cell adhesion, cellular calcium ion homeostasis, epidermis development, ion transmembrane transport, positive regulation of I-kappaB kinase/NF-kappaB cascade, signal transduction, transmembrane transport Golgi apparatus, Golgi membrane, integral to membrane, trans-Golgi network ATP binding, calcium-transporting ATPase activity, cation-transporting ATPase activity, metal ion binding, signal transducer activity Human ATP2C2 Reactome UniProtKB {GO:0019829=GO_REF:0000002, GO:0005388=GO_REF:0000003, GO:0034220=Reactome:REACT_25300, GO:0000139=Reactome:REACT_25301, GO:0016021=GO_REF:0000037, GO:0055085=Reactome:REACT_15518, GO:0005524=GO_REF:0000037, GO:0046872=GO_REF:0000037} O75185 Calcium-transporting ATPase type 2C member 2 protein 20130301 {GO:0019829=IEA, GO:0005388=IEA, GO:0034220=TAS, GO:0000139=TAS, GO:0016021=IEA, GO:0055085=TAS, GO:0005524=IEA, GO:0046872=IEA} ion transmembrane transport, transmembrane transport Golgi membrane, integral to membrane ATP binding, calcium-transporting ATPase activity, cation-transporting ATPase activity, metal ion binding Human ATP4A Reactome UniProtKB {GO:0000287=GO_REF:0000002, GO:0005886=Reactome:REACT_25173, GO:0046982=GO_REF:0000019, GO:0042493=GO_REF:0000019, GO:0045851=GO_REF:0000019, GO:0008900=GO_REF:0000003, GO:0055085=Reactome:REACT_15518, GO:0005524=GO_REF:0000037, GO:0019829=GO_REF:0000002, GO:0006754=GO_REF:0000002, GO:0034220=Reactome:REACT_25300, GO:0005887=PMID:2160952, GO:0015991=GO_REF:0000002, GO:0006810=PMID:2160952, GO:0010155=GO_REF:0000019, GO:0016021=GO_REF:0000002} P20648 Potassium-transporting ATPase alpha chain 1 protein 20130301 {GO:0000287=IEA, GO:0005886=TAS, GO:0046982=IEA, GO:0042493=IEA, GO:0045851=IEA, GO:0008900=IEA, GO:0055085=TAS, GO:0005524=IEA, GO:0019829=IEA, GO:0006754=IEA, GO:0034220=TAS, GO:0005887=TAS, GO:0015991=IEA, GO:0006810=TAS, GO:0010155=IEA, GO:0016021=IEA} ATP biosynthetic process, ATP hydrolysis coupled proton transport, ion transmembrane transport, pH reduction, regulation of proton transport, response to drug, transmembrane transport, transport integral to membrane, integral to plasma membrane, plasma membrane ATP binding, cation-transporting ATPase activity, hydrogen:potassium-exchanging ATPase activity, magnesium ion binding, protein heterodimerization activity Human ATP4B Reactome UniProtKB {GO:0034220=Reactome:REACT_25300, GO:0005886=Reactome:REACT_25173, GO:0032496=GO_REF:0000019, GO:0010243=GO_REF:0000019, GO:0008900=PMID:1656976, GO:0007155=GO_REF:0000037, GO:0006814=GO_REF:0000002, GO:0005890=GO_REF:0000002, GO:0055085=Reactome:REACT_15518} P51164 Potassium-transporting ATPase subunit beta protein 20121219 {GO:0034220=TAS, GO:0005886=TAS, GO:0032496=IEA, GO:0010243=IEA, GO:0008900=TAS, GO:0007155=IEA, GO:0006814=IEA, GO:0005890=IEA, GO:0055085=TAS} cell adhesion, ion transmembrane transport, response to lipopolysaccharide, response to organic nitrogen, sodium ion transport, transmembrane transport plasma membrane, sodium:potassium-exchanging ATPase complex hydrogen:potassium-exchanging ATPase activity Human ATP5A1 GOC UniProtKB {GO:0006629=GO_REF:0000024, GO:0005515=PMID:22309213, GO:0043499=PMID:10077593, GO:0042288=PMID:17643490, GO:0006200=PMID:12110673, GO:0005886=PMID:10077593, GO:0005743=PMID:19016746, GO:0044281=Reactome:REACT_111217, GO:0009790=GO_REF:0000024, GO:0005739=PMID:1830491, GO:0006754=PMID:1830491, GO:0008180=PMID:18850735, GO:0046961=GO_REF:0000002, GO:0005759=Reactome:REACT_1985, GO:0016887=PMID:12110673, GO:0015986=GO_REF:0000002, GO:0046034=GO_REF:0000002, GO:0022857=PMID:12110673, GO:0005524=GO_REF:0000024, GO:0005753=PMID:12110673, GO:0022904=Reactome:REACT_6305, GO:0001937=PMID:10077593, GO:0046933=GO_REF:0000024, GO:0042776=Reactome:REACT_6759, GO:0045261=GO_REF:0000037, GO:0015991=GO_REF:0000002, GO:0015992=GO_REF:0000002} P25705 ATP synthase subunit alpha, mitochondrial protein 20130413 {GO:0006629=ISS, GO:0005515=IPI, GO:0043499=IDA, GO:0042288=IDA, GO:0006200=IDA, GO:0005886=IDA, GO:0005743=IDA, GO:0044281=TAS, GO:0009790=ISS, GO:0005739=NAS, GO:0006754=NAS, GO:0008180=IDA, GO:0046961=IEA, GO:0005759=TAS, GO:0016887=IDA, GO:0015986=IEA, GO:0046034=IEA, GO:0022857=IC, GO:0005524=ISS, GO:0005753=IDA, GO:0022904=TAS, GO:0001937=IMP, GO:0046933=ISS, GO:0042776=TAS, GO:0045261=IEA, GO:0015991=IEA, GO:0015992=IEA} ATP biosynthetic process, ATP catabolic process, ATP hydrolysis coupled proton transport, ATP metabolic process, ATP synthesis coupled proton transport, embryo development, lipid metabolic process, mitochondrial ATP synthesis coupled proton transport, negative regulation of endothelial cell proliferation, proton transport, respiratory electron transport chain, small molecule metabolic process mitochondrial inner membrane, mitochondrial matrix, mitochondrial proton-transporting ATP synthase complex, mitochondrion, plasma membrane, proton-transporting ATP synthase complex, catalytic core F(1), signalosome ATP binding, ATPase activity, MHC class I protein binding, eukaryotic cell surface binding, protein binding, proton-transporting ATP synthase activity, rotational mechanism, proton-transporting ATPase activity, rotational mechanism, transmembrane transporter activity Human ATP5B GOC UniProtKB {GO:0042645=PMID:18063578, GO:0005515=PMID:10077593, GO:0006629=GO_REF:0000019, GO:0005215=PMID:2870059, GO:0043499=PMID:10077593, GO:0042288=PMID:17643490, GO:0006200=PMID:12110673, GO:0005886=PMID:10077593, GO:0044281=Reactome:REACT_111217, GO:0006091=PMID:2870059, GO:0005739=GO_REF:0000052, GO:0006754=PMID:17510399, GO:0046961=PMID:17510399, GO:0005759=Reactome:REACT_1985, GO:0006933=GO_REF:0000019, GO:0016887=PMID:12110673, GO:0031966=PMID:8006588, GO:0015986=GO_REF:0000002, GO:0009986=PMID:17510399, GO:0022857=PMID:12110673, GO:0001525=PMID:17510399, GO:0005524=GO_REF:0000037, GO:0005754=PMID:2870059, GO:0005753=PMID:12110673, GO:0022904=Reactome:REACT_6305, GO:0046933=GO_REF:0000002, GO:0042776=Reactome:REACT_6759, GO:0045261=GO_REF:0000002, GO:0015991=GO_REF:0000002, GO:0051453=PMID:17510399, GO:0015992=PMID:17510399} P06576 ATP synthase subunit beta, mitochondrial protein 20130413 {GO:0042645=IDA, GO:0005515=IPI, GO:0006629=IEA, GO:0005215=NAS, GO:0043499=IDA, GO:0042288=IDA, GO:0006200=IDA, GO:0005886=IDA, GO:0044281=TAS, GO:0006091=NAS, GO:0005739=IDA, GO:0006754=IMP, GO:0046961=IMP, GO:0005759=TAS, GO:0006933=IEA, GO:0016887=IDA, GO:0031966=IDA, GO:0015986=IEA, GO:0009986=IDA, GO:0022857=IC, GO:0001525=IMP, GO:0005524=IEA, GO:0005754=NAS, GO:0005753=IDA, GO:0022904=TAS, GO:0046933=IEA, GO:0042776=TAS, GO:0045261=IEA, GO:0015991=IEA, GO:0051453=IMP, GO:0015992=IMP} ATP biosynthetic process, ATP catabolic process, ATP hydrolysis coupled proton transport, ATP synthesis coupled proton transport, angiogenesis, generation of precursor metabolites and energy, lipid metabolic process, mitochondrial ATP synthesis coupled proton transport, negative regulation of cell adhesion involved in substrate-bound cell migration, proton transport, regulation of intracellular pH, respiratory electron transport chain, small molecule metabolic process cell surface, mitochondrial matrix, mitochondrial membrane, mitochondrial nucleoid, mitochondrial proton-transporting ATP synthase complex, mitochondrial proton-transporting ATP synthase, catalytic core, mitochondrion, plasma membrane, proton-transporting ATP synthase complex, catalytic core F(1) ATP binding, ATPase activity, MHC class I protein binding, eukaryotic cell surface binding, protein binding, proton-transporting ATP synthase activity, rotational mechanism, proton-transporting ATPase activity, rotational mechanism, transmembrane transporter activity, transporter activity Human ATP5C1 GOC UniProtKB {GO:0015986=GO_REF:0000002, GO:0006200=PMID:8227057, GO:0022857=PMID:12110673, GO:0005743=GO_REF:0000024, GO:0044281=Reactome:REACT_111217, GO:0006119=PMID:8227057, GO:0005753=PMID:12110673, GO:0022904=Reactome:REACT_6305, GO:0005739=PMID:12887009, GO:0006754=PMID:8227057, GO:0046961=GO_REF:0000002, GO:0042776=Reactome:REACT_6759, GO:0005759=Reactome:REACT_1985, GO:0046933=GO_REF:0000002, GO:0045261=GO_REF:0000038, GO:0000275=PMID:8227057, GO:0016887=PMID:12110673} P36542 ATP synthase subunit gamma, mitochondrial protein 20130413 {GO:0015986=IEA, GO:0006200=NAS, GO:0022857=IC, GO:0005743=ISS, GO:0044281=TAS, GO:0006119=NAS, GO:0005753=IDA, GO:0022904=TAS, GO:0005739=NAS, GO:0006754=NAS, GO:0046961=IEA, GO:0042776=TAS, GO:0005759=TAS, GO:0046933=IEA, GO:0045261=IEA, GO:0000275=NAS, GO:0016887=IDA} ATP biosynthetic process, ATP catabolic process, ATP synthesis coupled proton transport, mitochondrial ATP synthesis coupled proton transport, oxidative phosphorylation, respiratory electron transport chain, small molecule metabolic process mitochondrial inner membrane, mitochondrial matrix, mitochondrial proton-transporting ATP synthase complex, mitochondrial proton-transporting ATP synthase complex, catalytic core F(1), mitochondrion, proton-transporting ATP synthase complex, catalytic core F(1) ATPase activity, proton-transporting ATP synthase activity, rotational mechanism, proton-transporting ATPase activity, rotational mechanism, transmembrane transporter activity Human ATP5D Reactome UniProtKB {GO:0005215=PMID:1531933, GO:0006200=PMID:12539966, GO:0022857=PMID:12110673, GO:0005743=GO_REF:0000024, GO:0044281=Reactome:REACT_111217, GO:0005524=PMID:12539966, GO:0005753=PMID:12110673, GO:0006119=PMID:12539966, GO:0022904=Reactome:REACT_6305, GO:0005739=PMID:12887009, GO:0006754=PMID:12539966, GO:0043531=PMID:12539966, GO:0046961=GO_REF:0000002, GO:0005759=Reactome:REACT_1985, GO:0046933=GO_REF:0000002, GO:0042776=Reactome:REACT_6759, GO:0000275=PMID:12539966, GO:0046688=PMID:12539966, GO:0016887=PMID:12110673} P30049 ATP synthase subunit delta, mitochondrial protein 20050630 {GO:0005215=NAS, GO:0006200=NAS, GO:0022857=IC, GO:0005743=ISS, GO:0044281=TAS, GO:0005524=NAS, GO:0005753=IDA, GO:0006119=NAS, GO:0022904=TAS, GO:0005739=NAS, GO:0006754=NAS, GO:0043531=NAS, GO:0046961=IEA, GO:0005759=TAS, GO:0046933=IEA, GO:0042776=TAS, GO:0000275=NAS, GO:0046688=NAS, GO:0016887=IDA} ATP biosynthetic process, ATP catabolic process, mitochondrial ATP synthesis coupled proton transport, oxidative phosphorylation, respiratory electron transport chain, response to copper ion, small molecule metabolic process mitochondrial inner membrane, mitochondrial matrix, mitochondrial proton-transporting ATP synthase complex, mitochondrial proton-transporting ATP synthase complex, catalytic core F(1), mitochondrion ADP binding, ATP binding, ATPase activity, proton-transporting ATP synthase activity, rotational mechanism, proton-transporting ATPase activity, rotational mechanism, transmembrane transporter activity, transporter activity Human ATP5E GOC UniProtKB {GO:0022904=Reactome:REACT_6305, GO:0006200=PMID:12110673, GO:0046961=GO_REF:0000002, GO:0005759=Reactome:REACT_1985, GO:0042776=Reactome:REACT_6759, GO:0046933=GO_REF:0000002, GO:0022857=PMID:12110673, GO:0044281=Reactome:REACT_111217, GO:0000275=GO_REF:0000002, GO:0016887=PMID:12110673, GO:0005753=PMID:12110673} P56381 ATP synthase subunit epsilon, mitochondrial protein 20130413 {GO:0022904=TAS, GO:0006200=IDA, GO:0046961=IEA, GO:0005759=TAS, GO:0042776=TAS, GO:0046933=IEA, GO:0022857=IC, GO:0044281=TAS, GO:0000275=IEA, GO:0016887=IDA, GO:0005753=IDA} ATP catabolic process, mitochondrial ATP synthesis coupled proton transport, respiratory electron transport chain, small molecule metabolic process mitochondrial matrix, mitochondrial proton-transporting ATP synthase complex, mitochondrial proton-transporting ATP synthase complex, catalytic core F(1) ATPase activity, proton-transporting ATP synthase activity, rotational mechanism, proton-transporting ATPase activity, rotational mechanism, transmembrane transporter activity Human ATP5F1 InterPro UniProtKB {GO:0005515=PMID:19016746, GO:0015986=GO_REF:0000002, GO:0006200=PMID:12110673, GO:0015078=GO_REF:0000002, GO:0022857=PMID:12110673, GO:0005743=Reactome:REACT_1985, GO:0044281=Reactome:REACT_111217, GO:0005753=PMID:12110673, GO:0022904=Reactome:REACT_6305, GO:0046933=GO_REF:0000033, GO:0005759=PMID:1831354, GO:0042776=Reactome:REACT_6759, GO:0000276=GO_REF:0000002, GO:0016887=PMID:12110673} Q5QNZ2 ATP synthase subunit b, mitochondrial protein 20130413 {GO:0005515=IPI, GO:0015986=IEA, GO:0006200=IDA, GO:0015078=IEA, GO:0022857=IC, GO:0005743=TAS, GO:0044281=TAS, GO:0005753=IDA, GO:0022904=TAS, GO:0046933=IBA, GO:0005759=NAS, GO:0042776=TAS, GO:0000276=IEA, GO:0016887=IDA} ATP catabolic process, ATP synthesis coupled proton transport, mitochondrial ATP synthesis coupled proton transport, respiratory electron transport chain, small molecule metabolic process mitochondrial inner membrane, mitochondrial matrix, mitochondrial proton-transporting ATP synthase complex, mitochondrial proton-transporting ATP synthase complex, coupling factor F(o) ATPase activity, hydrogen ion transmembrane transporter activity, protein binding, proton-transporting ATP synthase activity, rotational mechanism, transmembrane transporter activity Human InterPro:IPR008688|InterPro:IPR013837 ATP5G1 LIFEdb UniProtKB {GO:0005215=PMID:8328972, GO:0015986=GO_REF:0000002, GO:0015078=GO_REF:0000002, GO:0005743=Reactome:REACT_1985, GO:0044281=Reactome:REACT_111217, GO:0008289=GO_REF:0000037, GO:0005753=GO_REF:0000024, GO:0022904=Reactome:REACT_6305, GO:0005739=GO_REF:0000054, GO:0042776=Reactome:REACT_6759, GO:0015991=GO_REF:0000002, GO:0016021=GO_REF:0000037, GO:0045263=GO_REF:0000037} P05496 ATP synthase lipid-binding protein, mitochondrial protein 20100607 {GO:0005215=NAS, GO:0015986=IEA, GO:0015078=IEA, GO:0005743=TAS, GO:0044281=TAS, GO:0008289=IEA, GO:0005753=ISS, GO:0022904=TAS, GO:0005739=IDA, GO:0042776=TAS, GO:0015991=IEA, GO:0016021=IEA, GO:0045263=IEA} ATP hydrolysis coupled proton transport, ATP synthesis coupled proton transport, mitochondrial ATP synthesis coupled proton transport, respiratory electron transport chain, small molecule metabolic process integral to membrane, mitochondrial inner membrane, mitochondrial proton-transporting ATP synthase complex, mitochondrion, proton-transporting ATP synthase complex, coupling factor F(o) hydrogen ion transmembrane transporter activity, lipid binding, transporter activity Human ATP5G2 PINC UniProtKB {GO:0005215=PMID:8328972, GO:0015986=GO_REF:0000002, GO:0045471=GO_REF:0000019, GO:0015078=GO_REF:0000002, GO:0015991=GO_REF:0000002, GO:0016021=GO_REF:0000037, GO:0045263=GO_REF:0000037, GO:0005753=PMID:8328972, GO:0008289=GO_REF:0000037} Q06055 ATP synthase lipid-binding protein, mitochondrial protein 20040811 {GO:0005215=NAS, GO:0015986=IEA, GO:0045471=IEA, GO:0015078=IEA, GO:0015991=IEA, GO:0016021=IEA, GO:0045263=IEA, GO:0005753=TAS, GO:0008289=IEA} ATP hydrolysis coupled proton transport, ATP synthesis coupled proton transport, response to ethanol integral to membrane, mitochondrial proton-transporting ATP synthase complex, proton-transporting ATP synthase complex, coupling factor F(o) hydrogen ion transmembrane transporter activity, lipid binding, transporter activity Human ATP5G3 PINC UniProtKB {GO:0005215=PMID:7698763, GO:0015986=GO_REF:0000002, GO:0015078=GO_REF:0000002, GO:0015991=GO_REF:0000002, GO:0016021=GO_REF:0000037, GO:0045263=GO_REF:0000037, GO:0005753=PMID:7698763, GO:0008289=GO_REF:0000037} P48201 ATP synthase lipid-binding protein, mitochondrial protein 20030904 {GO:0005215=NAS, GO:0015986=IEA, GO:0015078=IEA, GO:0015991=IEA, GO:0016021=IEA, GO:0045263=IEA, GO:0005753=TAS, GO:0008289=IEA} ATP hydrolysis coupled proton transport, ATP synthesis coupled proton transport integral to membrane, mitochondrial proton-transporting ATP synthase complex, proton-transporting ATP synthase complex, coupling factor F(o) hydrogen ion transmembrane transporter activity, lipid binding, transporter activity Human ATP5H GOC UniProtKB {GO:0022904=Reactome:REACT_6305, GO:0015986=GO_REF:0000002, GO:0006200=PMID:12110673, GO:0042776=Reactome:REACT_6759, GO:0015078=GO_REF:0000002, GO:0022857=PMID:12110673, GO:0005743=Reactome:REACT_1985, GO:0000276=GO_REF:0000002, GO:0044281=Reactome:REACT_111217, GO:0016887=PMID:12110673, GO:0005753=PMID:12110673} O75947 ATP synthase subunit d, mitochondrial protein 20130413 {GO:0022904=TAS, GO:0015986=IEA, GO:0006200=IDA, GO:0042776=TAS, GO:0015078=IEA, GO:0022857=IC, GO:0005743=TAS, GO:0000276=IEA, GO:0044281=TAS, GO:0016887=IDA, GO:0005753=IDA} ATP catabolic process, ATP synthesis coupled proton transport, mitochondrial ATP synthesis coupled proton transport, respiratory electron transport chain, small molecule metabolic process mitochondrial inner membrane, mitochondrial proton-transporting ATP synthase complex, mitochondrial proton-transporting ATP synthase complex, coupling factor F(o) ATPase activity, hydrogen ion transmembrane transporter activity, transmembrane transporter activity Human ATP5I GOC UniProtKB {GO:0005739=GO_REF:0000052, GO:0022904=Reactome:REACT_6305, GO:0006200=PMID:12110673, GO:0042776=Reactome:REACT_6759, GO:0015078=GO_REF:0000002, GO:0022857=PMID:12110673, GO:0005743=Reactome:REACT_1985, GO:0000276=GO_REF:0000019, GO:0044281=Reactome:REACT_111217, GO:0016887=PMID:12110673, GO:0005753=PMID:12110673} P56385 ATP synthase subunit e, mitochondrial protein 20130413 {GO:0005739=IDA, GO:0022904=TAS, GO:0006200=IDA, GO:0042776=TAS, GO:0015078=IEA, GO:0022857=IC, GO:0005743=TAS, GO:0000276=IEA, GO:0044281=TAS, GO:0016887=IDA, GO:0005753=IDA} ATP catabolic process, mitochondrial ATP synthesis coupled proton transport, respiratory electron transport chain, small molecule metabolic process mitochondrial inner membrane, mitochondrial proton-transporting ATP synthase complex, mitochondrial proton-transporting ATP synthase complex, coupling factor F(o), mitochondrion ATPase activity, hydrogen ion transmembrane transporter activity, transmembrane transporter activity Human ATP5J GOC UniProtKB {GO:0005215=PMID:1830479, GO:0015986=GO_REF:0000002, GO:0006200=PMID:12110673, GO:0015078=GO_REF:0000002, GO:0022857=PMID:12110673, GO:0005743=Reactome:REACT_1985, GO:0044281=Reactome:REACT_111217, GO:0005753=PMID:12110673, GO:0005739=GO_REF:0000052, GO:0022904=Reactome:REACT_6305, GO:0042776=Reactome:REACT_6759, GO:0000276=GO_REF:0000002, GO:0016887=PMID:12110673} P18859 ATP synthase-coupling factor 6, mitochondrial protein 20130413 {GO:0005215=NAS, GO:0015986=IEA, GO:0006200=IDA, GO:0015078=IEA, GO:0022857=IC, GO:0005743=TAS, GO:0044281=TAS, GO:0005753=IDA, GO:0005739=IDA, GO:0022904=TAS, GO:0042776=TAS, GO:0000276=IEA, GO:0016887=IDA} ATP catabolic process, ATP synthesis coupled proton transport, mitochondrial ATP synthesis coupled proton transport, respiratory electron transport chain, small molecule metabolic process mitochondrial inner membrane, mitochondrial proton-transporting ATP synthase complex, mitochondrial proton-transporting ATP synthase complex, coupling factor F(o), mitochondrion ATPase activity, hydrogen ion transmembrane transporter activity, transmembrane transporter activity, transporter activity Human ATP5J2 GOC UniProtKB {GO:0022904=Reactome:REACT_6305, GO:0006200=PMID:12110673, GO:0042776=Reactome:REACT_6759, GO:0022857=PMID:12110673, GO:0005743=Reactome:REACT_1985, GO:0044281=Reactome:REACT_111217, GO:0016021=GO_REF:0000037, GO:0016887=PMID:12110673, GO:0045263=GO_REF:0000037, GO:0015992=PMID:11959398, GO:0005753=PMID:12110673} P56134 ATP synthase subunit f, mitochondrial protein 20130413 {GO:0022904=TAS, GO:0006200=IDA, GO:0042776=TAS, GO:0022857=IC, GO:0005743=TAS, GO:0044281=TAS, GO:0016021=IEA, GO:0016887=IDA, GO:0045263=IEA, GO:0015992=NAS, GO:0005753=IDA} ATP catabolic process, mitochondrial ATP synthesis coupled proton transport, proton transport, respiratory electron transport chain, small molecule metabolic process integral to membrane, mitochondrial inner membrane, mitochondrial proton-transporting ATP synthase complex, proton-transporting ATP synthase complex, coupling factor F(o) ATPase activity, transmembrane transporter activity Human ATP5L GOC UniProtKB {GO:0005739=GO_REF:0000054, GO:0022904=Reactome:REACT_6305, GO:0015986=GO_REF:0000002, GO:0006200=PMID:12110673, GO:0042776=Reactome:REACT_6759, GO:0015078=GO_REF:0000002, GO:0022857=PMID:12110673, GO:0005743=Reactome:REACT_1985, GO:0000276=GO_REF:0000002, GO:0044281=Reactome:REACT_111217, GO:0016887=PMID:12110673, GO:0005753=PMID:12110673} O75964 ATP synthase subunit g, mitochondrial protein 20130413 {GO:0005739=IDA, GO:0022904=TAS, GO:0015986=IEA, GO:0006200=IDA, GO:0042776=TAS, GO:0015078=IEA, GO:0022857=IC, GO:0005743=TAS, GO:0000276=IEA, GO:0044281=TAS, GO:0016887=IDA, GO:0005753=IDA} ATP catabolic process, ATP synthesis coupled proton transport, mitochondrial ATP synthesis coupled proton transport, respiratory electron transport chain, small molecule metabolic process mitochondrial inner membrane, mitochondrial proton-transporting ATP synthase complex, mitochondrial proton-transporting ATP synthase complex, coupling factor F(o), mitochondrion ATPase activity, hydrogen ion transmembrane transporter activity, transmembrane transporter activity Human ATP5O Reactome UniProtKB {GO:0005215=PMID:7490082, GO:0015986=GO_REF:0000002, GO:0005886=PMID:17851741, GO:0006200=PMID:12110673, GO:0022857=PMID:12110673, GO:0005743=Reactome:REACT_1985, GO:0044281=Reactome:REACT_111217, GO:0032403=GO_REF:0000019, GO:0005753=PMID:7490082, GO:0022904=Reactome:REACT_6305, GO:0005739=PMID:17851741, GO:0006754=PMID:17851741, GO:0008144=PMID:15850986, GO:0046933=GO_REF:0000002, GO:0042776=Reactome:REACT_6759, GO:0000276=GO_REF:0000019, GO:0005496=GO_REF:0000019, GO:0016887=PMID:12110673, GO:0015992=PMID:17851741} P48047 ATP synthase subunit O, mitochondrial protein 20050526 {GO:0005215=NAS, GO:0015986=IEA, GO:0005886=IDA, GO:0006200=IDA, GO:0022857=IC, GO:0005743=TAS, GO:0044281=TAS, GO:0032403=IEA, GO:0005753=NAS, GO:0022904=TAS, GO:0005739=IDA, GO:0006754=NAS, GO:0008144=IDA, GO:0046933=IEA, GO:0042776=TAS, GO:0000276=IEA, GO:0005496=IEA, GO:0016887=IDA, GO:0015992=NAS} ATP biosynthetic process, ATP catabolic process, ATP synthesis coupled proton transport, mitochondrial ATP synthesis coupled proton transport, proton transport, respiratory electron transport chain, small molecule metabolic process mitochondrial inner membrane, mitochondrial proton-transporting ATP synthase complex, mitochondrial proton-transporting ATP synthase complex, coupling factor F(o), mitochondrion, plasma membrane ATPase activity, drug binding, protein complex binding, proton-transporting ATP synthase activity, rotational mechanism, steroid binding, transmembrane transporter activity, transporter activity Human ATP5S UniProtKB UniProtKB {GO:0006754=GO_REF:0000037, GO:0015078=PMID:6143319, GO:0005743=GO_REF:0000039, GO:0046872=GO_REF:0000037, GO:0045263=GO_REF:0000037, GO:0015992=PMID:6143319} Q99766 ATP synthase subunit s, mitochondrial protein 20021112 {GO:0006754=IEA, GO:0015078=NAS, GO:0005743=IEA, GO:0046872=IEA, GO:0045263=IEA, GO:0015992=NAS} ATP biosynthetic process, proton transport mitochondrial inner membrane, proton-transporting ATP synthase complex, coupling factor F(o) hydrogen ion transmembrane transporter activity, metal ion binding Human ATP6AP1 PINC UniProtKB {GO:0005215=PMID:8733135, GO:0005774=GO_REF:0000039, GO:0046961=GO_REF:0000002, GO:0046933=GO_REF:0000002, GO:0016469=PMID:8733135, GO:0015991=GO_REF:0000002, GO:0033180=GO_REF:0000002, GO:0016021=GO_REF:0000037, GO:0005524=GO_REF:0000037, GO:0015992=PMID:8733135} Q15904 V-type proton ATPase subunit S1 protein 20030904 {GO:0005215=TAS, GO:0005774=IEA, GO:0046961=IEA, GO:0046933=IEA, GO:0016469=TAS, GO:0015991=IEA, GO:0033180=IEA, GO:0016021=IEA, GO:0005524=IEA, GO:0015992=TAS} ATP hydrolysis coupled proton transport, proton transport integral to membrane, proton-transporting V-type ATPase, V1 domain, proton-transporting two-sector ATPase complex, vacuolar membrane ATP binding, proton-transporting ATP synthase activity, rotational mechanism, proton-transporting ATPase activity, rotational mechanism, transporter activity Human ATP6AP2 HGNC UniProtKB {GO:0005515=PMID:12045255, GO:0043005=GO_REF:0000019, GO:0002003=PMID:15746149, GO:0005886=Reactome:REACT_147891, GO:0044297=GO_REF:0000019, GO:0032914=PMID:16374430, GO:0043408=PMID:15746149, GO:0004872=GO_REF:0000002, GO:0016021=GO_REF:0000037, GO:0004190=Reactome:REACT_147891, GO:0019899=GO_REF:0000019, GO:0044267=Reactome:REACT_17015, GO:0009897=PMID:15746149} O75787 Renin receptor protein 20070129 {GO:0005515=IPI, GO:0043005=IEA, GO:0002003=IDA, GO:0005886=TAS, GO:0044297=IEA, GO:0032914=IDA, GO:0043408=IDA, GO:0004872=IEA, GO:0016021=IEA, GO:0004190=EXP, GO:0019899=IEA, GO:0044267=TAS, GO:0009897=IDA} angiotensin maturation, cellular protein metabolic process, positive regulation of transforming growth factor beta1 production, regulation of MAPK cascade cell body, external side of plasma membrane, integral to membrane, neuron projection, plasma membrane aspartic-type endopeptidase activity, enzyme binding, protein binding, receptor activity Human ATP6V0A1 HPA UniProtKB {GO:0008286=Reactome:REACT_498, GO:0005515=PMID:12649290, GO:0042470=GO_REF:0000039, GO:0005794=GO_REF:0000052, GO:0051701=Reactome:REACT_121237, GO:0005886=PMID:17360703, GO:0015078=GO_REF:0000002, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0055085=Reactome:REACT_15518, GO:0043231=GO_REF:0000052, GO:0006879=Reactome:REACT_25060, GO:0000220=GO_REF:0000002, GO:0033572=Reactome:REACT_25283, GO:0005737=GO_REF:0000052, GO:0030670=Reactome:REACT_121163, GO:0015991=GO_REF:0000002, GO:0051117=PMID:17360703, GO:0016021=GO_REF:0000037, GO:0090382=Reactome:REACT_121256, GO:0010008=Reactome:REACT_25268, GO:0033179=GO_REF:0000002} Q93050 V-type proton ATPase 116 kDa subunit a isoform 1 protein 20101115 {GO:0008286=TAS, GO:0005515=IPI, GO:0042470=IEA, GO:0005794=IDA, GO:0051701=TAS, GO:0005886=IDA, GO:0015078=IEA, GO:0005730=IDA, GO:0005634=IDA, GO:0055085=TAS, GO:0043231=IDA, GO:0006879=TAS, GO:0000220=IEA, GO:0033572=TAS, GO:0005737=IDA, GO:0030670=TAS, GO:0015991=IEA, GO:0051117=IPI, GO:0016021=IEA, GO:0090382=TAS, GO:0010008=TAS, GO:0033179=IEA} ATP hydrolysis coupled proton transport, cellular iron ion homeostasis, insulin receptor signaling pathway, interaction with host, phagosome maturation, transferrin transport, transmembrane transport Golgi apparatus, cytoplasm, endosome membrane, integral to membrane, intracellular membrane-bounded organelle, melanosome, nucleolus, nucleus, phagocytic vesicle membrane, plasma membrane, proton-transporting V-type ATPase, V0 domain, vacuolar proton-transporting V-type ATPase, V0 domain ATPase binding, hydrogen ion transmembrane transporter activity, protein binding Human ATP6V0A2 HPA UniProtKB {GO:0005515=PMID:16415858, GO:0008286=Reactome:REACT_498, GO:0005886=GO_REF:0000052, GO:0001669=GO_REF:0000019, GO:0051701=Reactome:REACT_121237, GO:0015078=GO_REF:0000002, GO:0055085=Reactome:REACT_15518, GO:0000220=GO_REF:0000002, GO:0006879=Reactome:REACT_25060, GO:0033572=Reactome:REACT_25283, GO:0005737=GO_REF:0000052, GO:0006955=PMID:2247090, GO:0015991=GO_REF:0000002, GO:0030670=Reactome:REACT_121163, GO:0016021=GO_REF:0000037, GO:0090382=Reactome:REACT_121256, GO:0033179=GO_REF:0000002, GO:0010008=Reactome:REACT_25268} Q9Y487 V-type proton ATPase 116 kDa subunit a isoform 2 protein 20111111 {GO:0005515=IPI, GO:0008286=TAS, GO:0005886=IDA, GO:0001669=IEA, GO:0051701=TAS, GO:0015078=IEA, GO:0055085=TAS, GO:0000220=IEA, GO:0006879=TAS, GO:0033572=TAS, GO:0005737=IDA, GO:0006955=TAS, GO:0015991=IEA, GO:0030670=TAS, GO:0016021=IEA, GO:0090382=TAS, GO:0033179=IEA, GO:0010008=TAS} ATP hydrolysis coupled proton transport, cellular iron ion homeostasis, immune response, insulin receptor signaling pathway, interaction with host, phagosome maturation, transferrin transport, transmembrane transport acrosomal vesicle, cytoplasm, endosome membrane, integral to membrane, phagocytic vesicle membrane, plasma membrane, proton-transporting V-type ATPase, V0 domain, vacuolar proton-transporting V-type ATPase, V0 domain hydrogen ion transmembrane transporter activity, protein binding Human ATP6V0A4 Reactome UniProtKB {GO:0005515=PMID:12649290, GO:0008286=Reactome:REACT_498, GO:0005886=PMID:17360703, GO:0015078=GO_REF:0000002, GO:0007605=PMID:12414817, GO:0031526=PMID:14638902, GO:0006885=PMID:10973252, GO:0000220=GO_REF:0000002, GO:0006879=Reactome:REACT_25060, GO:0033572=Reactome:REACT_25283, GO:0016324=PMID:10973252, GO:0030670=Reactome:REACT_121163, GO:0051117=PMID:17360703, GO:0090382=Reactome:REACT_121256, GO:0007588=PMID:12414817, GO:0051701=Reactome:REACT_121237, GO:0045177=PMID:14638902, GO:0055085=Reactome:REACT_15518, GO:0001503=PMID:10973252, GO:0015991=GO_REF:0000019, GO:0016021=GO_REF:0000037, GO:0016471=PMID:10973252, GO:0010008=Reactome:REACT_25268, GO:0005768=GO_REF:0000024, GO:0015992=PMID:10973252} Q9HBG4 V-type proton ATPase 116 kDa subunit a isoform 4 protein 20110228 {GO:0005515=IPI, GO:0008286=TAS, GO:0005886=IDA, GO:0015078=IEA, GO:0007605=IMP, GO:0031526=IDA, GO:0006885=IMP, GO:0000220=IEA, GO:0006879=TAS, GO:0033572=TAS, GO:0016324=IDA, GO:0030670=TAS, GO:0051117=IPI, GO:0090382=TAS, GO:0007588=IMP, GO:0051701=TAS, GO:0045177=IDA, GO:0055085=TAS, GO:0001503=IMP, GO:0015991=IEA, GO:0016021=IEA, GO:0016471=IDA, GO:0010008=TAS, GO:0005768=ISS, GO:0015992=IMP} ATP hydrolysis coupled proton transport, cellular iron ion homeostasis, excretion, insulin receptor signaling pathway, interaction with host, ossification, phagosome maturation, proton transport, regulation of pH, sensory perception of sound, transferrin transport, transmembrane transport apical part of cell, apical plasma membrane, brush border membrane, endosome, endosome membrane, integral to membrane, phagocytic vesicle membrane, plasma membrane, vacuolar proton-transporting V-type ATPase complex, vacuolar proton-transporting V-type ATPase, V0 domain ATPase binding, hydrogen ion transmembrane transporter activity, protein binding Human ATP6V0B Reactome UniProtKB {GO:0008286=Reactome:REACT_498, GO:0005774=GO_REF:0000039, GO:0005215=PMID:9653649, GO:0051701=Reactome:REACT_121237, GO:0015078=GO_REF:0000002, GO:0055085=Reactome:REACT_15518, GO:0006879=Reactome:REACT_25060, GO:0033572=Reactome:REACT_25283, GO:0015991=GO_REF:0000002, GO:0030670=Reactome:REACT_121163, GO:0016021=GO_REF:0000019, GO:0090382=Reactome:REACT_121256, GO:0033179=GO_REF:0000002, GO:0010008=Reactome:REACT_25268, GO:0005768=GO_REF:0000019, GO:0015992=PMID:9653649} Q99437 V-type proton ATPase 21 kDa proteolipid subunit protein 20110228 {GO:0008286=TAS, GO:0005774=IEA, GO:0005215=TAS, GO:0051701=TAS, GO:0015078=IEA, GO:0055085=TAS, GO:0006879=TAS, GO:0033572=TAS, GO:0015991=IEA, GO:0030670=TAS, GO:0016021=IEA, GO:0090382=TAS, GO:0033179=IEA, GO:0010008=TAS, GO:0005768=IEA, GO:0015992=TAS} ATP hydrolysis coupled proton transport, cellular iron ion homeostasis, insulin receptor signaling pathway, interaction with host, phagosome maturation, proton transport, transferrin transport, transmembrane transport endosome, endosome membrane, integral to membrane, phagocytic vesicle membrane, proton-transporting V-type ATPase, V0 domain, vacuolar membrane hydrogen ion transmembrane transporter activity, transporter activity Human ATP6V0C IntAct UniProtKB {GO:0005515=PMID:21988832, GO:0008286=Reactome:REACT_498, GO:0005774=GO_REF:0000039, GO:0051701=Reactome:REACT_121237, GO:0015078=GO_REF:0000002, GO:0055085=Reactome:REACT_15518, GO:0006879=Reactome:REACT_25060, GO:0033572=Reactome:REACT_25283, GO:0046961=PMID:1709739, GO:0019048=GO_REF:0000037, GO:0046933=PMID:1709739, GO:0030670=Reactome:REACT_121163, GO:0015991=GO_REF:0000002, GO:0016021=GO_REF:0000037, GO:0090382=Reactome:REACT_121256, GO:0031625=PMID:18298843, GO:0010008=Reactome:REACT_25268, GO:0033179=GO_REF:0000002, GO:0015992=PMID:1709739} P27449 V-type proton ATPase 16 kDa proteolipid subunit protein 20130415 {GO:0005515=IPI, GO:0008286=TAS, GO:0005774=IEA, GO:0051701=TAS, GO:0015078=IEA, GO:0055085=TAS, GO:0006879=TAS, GO:0033572=TAS, GO:0046961=TAS, GO:0019048=IEA, GO:0046933=TAS, GO:0030670=TAS, GO:0015991=IEA, GO:0016021=IEA, GO:0090382=TAS, GO:0031625=IPI, GO:0010008=TAS, GO:0033179=IEA, GO:0015992=TAS} ATP hydrolysis coupled proton transport, cellular iron ion homeostasis, insulin receptor signaling pathway, interaction with host, phagosome maturation, proton transport, transferrin transport, transmembrane transport, virus-host interaction endosome membrane, integral to membrane, phagocytic vesicle membrane, proton-transporting V-type ATPase, V0 domain, vacuolar membrane hydrogen ion transmembrane transporter activity, protein binding, proton-transporting ATP synthase activity, rotational mechanism, proton-transporting ATPase activity, rotational mechanism, ubiquitin protein ligase binding Human UniProtKB:Q96G23 ATP6V0D1 Reactome UniProtKB {GO:0005515=PMID:18752060, GO:0008286=Reactome:REACT_498, GO:0015078=GO_REF:0000002, GO:0032403=GO_REF:0000019, GO:0030968=Reactome:REACT_18356, GO:0006879=Reactome:REACT_25060, GO:0033572=Reactome:REACT_25283, GO:0016324=GO_REF:0000019, GO:0008553=GO_REF:0000019, GO:0030670=Reactome:REACT_121163, GO:0043679=GO_REF:0000019, GO:0090382=Reactome:REACT_121256, GO:0033179=GO_REF:0000002, GO:0051701=Reactome:REACT_121237, GO:0055085=Reactome:REACT_15518, GO:0008021=GO_REF:0000019, GO:0016020=PMID:18752060, GO:0007420=GO_REF:0000019, GO:0015991=GO_REF:0000002, GO:0006987=Reactome:REACT_18368, GO:0044267=Reactome:REACT_17015, GO:0016471=PMID:18752060, GO:0005769=GO_REF:0000019, GO:0010008=Reactome:REACT_115786, GO:0015992=PMID:11118322} P61421 V-type proton ATPase subunit d 1 protein 20110228 {GO:0005515=IPI, GO:0008286=TAS, GO:0015078=IEA, GO:0032403=IEA, GO:0030968=TAS, GO:0006879=TAS, GO:0033572=TAS, GO:0016324=IEA, GO:0008553=IEA, GO:0030670=TAS, GO:0043679=IEA, GO:0090382=TAS, GO:0033179=IEA, GO:0051701=TAS, GO:0055085=TAS, GO:0008021=IEA, GO:0016020=IDA, GO:0007420=IEA, GO:0015991=IEA, GO:0006987=TAS, GO:0044267=TAS, GO:0016471=IDA, GO:0005769=IEA, GO:0010008=TAS, GO:0015992=NAS} ATP hydrolysis coupled proton transport, activation of signaling protein activity involved in unfolded protein response, brain development, cellular iron ion homeostasis, cellular protein metabolic process, endoplasmic reticulum unfolded protein response, insulin receptor signaling pathway, interaction with host, phagosome maturation, proton transport, transferrin transport, transmembrane transport apical plasma membrane, axon terminus, early endosome, endosome membrane, membrane, phagocytic vesicle membrane, proton-transporting V-type ATPase, V0 domain, synaptic vesicle, vacuolar proton-transporting V-type ATPase complex hydrogen ion transmembrane transporter activity, hydrogen-exporting ATPase activity, phosphorylative mechanism, protein binding, protein complex binding Human ATP6V0D2 Reactome UniProtKB {GO:0005515=PMID:18752060, GO:0008286=Reactome:REACT_498, GO:0051701=Reactome:REACT_121237, GO:0015078=GO_REF:0000002, GO:0055085=Reactome:REACT_15518, GO:0006879=Reactome:REACT_25060, GO:0033572=Reactome:REACT_25283, GO:0016324=PMID:15800125, GO:0016020=PMID:18752060, GO:0015991=GO_REF:0000002, GO:0030670=Reactome:REACT_121163, GO:0090382=Reactome:REACT_121256, GO:0010008=Reactome:REACT_25268, GO:0016471=PMID:18752060, GO:0005769=GO_REF:0000019, GO:0033179=GO_REF:0000002} Q8N8Y2 V-type proton ATPase subunit d 2 protein 20110228 {GO:0005515=IPI, GO:0008286=TAS, GO:0051701=TAS, GO:0015078=IEA, GO:0055085=TAS, GO:0006879=TAS, GO:0033572=TAS, GO:0016324=IDA, GO:0016020=IDA, GO:0015991=IEA, GO:0030670=TAS, GO:0090382=TAS, GO:0010008=TAS, GO:0016471=IDA, GO:0005769=IEA, GO:0033179=IEA} ATP hydrolysis coupled proton transport, cellular iron ion homeostasis, insulin receptor signaling pathway, interaction with host, phagosome maturation, transferrin transport, transmembrane transport apical plasma membrane, early endosome, endosome membrane, membrane, phagocytic vesicle membrane, proton-transporting V-type ATPase, V0 domain, vacuolar proton-transporting V-type ATPase complex hydrogen ion transmembrane transporter activity, protein binding Human ATP6V0E1 Reactome UniProtKB {GO:0008286=Reactome:REACT_498, GO:0005215=PMID:9556572, GO:0051701=Reactome:REACT_121237, GO:0015078=GO_REF:0000002, GO:0042625=GO_REF:0000024, GO:0055085=Reactome:REACT_15518, GO:0006879=Reactome:REACT_25060, GO:0033572=Reactome:REACT_25283, GO:0016020=PMID:9556572, GO:0007035=GO_REF:0000024, GO:0046961=PMID:9556572, GO:0030670=Reactome:REACT_121163, GO:0015991=GO_REF:0000002, GO:0016049=PMID:17350184, GO:0016021=GO_REF:0000037, GO:0090382=Reactome:REACT_121256, GO:0043200=GO_REF:0000019, GO:0010008=Reactome:REACT_25268, GO:0033179=GO_REF:0000002, GO:0015992=PMID:9556572} O15342 V-type proton ATPase subunit e 1 protein 20110228 {GO:0008286=TAS, GO:0005215=NAS, GO:0051701=TAS, GO:0015078=IEA, GO:0042625=ISS, GO:0055085=TAS, GO:0006879=TAS, GO:0033572=TAS, GO:0016020=TAS, GO:0007035=ISS, GO:0046961=TAS, GO:0030670=TAS, GO:0015991=IEA, GO:0016049=IGI, GO:0016021=IEA, GO:0090382=TAS, GO:0043200=IEA, GO:0010008=TAS, GO:0033179=IEA, GO:0015992=TAS} ATP hydrolysis coupled proton transport, cell growth, cellular iron ion homeostasis, insulin receptor signaling pathway, interaction with host, phagosome maturation, proton transport, response to amino acid stimulus, transferrin transport, transmembrane transport, vacuolar acidification endosome membrane, integral to membrane, membrane, phagocytic vesicle membrane, proton-transporting V-type ATPase, V0 domain ATPase activity, coupled to transmembrane movement of ions, hydrogen ion transmembrane transporter activity, proton-transporting ATPase activity, rotational mechanism, transporter activity Human ATP6V1A Reactome UniProtKB {GO:0008286=Reactome:REACT_498, GO:0046034=GO_REF:0000002, GO:0051701=Reactome:REACT_121237, GO:0005886=GO_REF:0000024, GO:0016469=PMID:8463241, GO:0033180=GO_REF:0000002, GO:0055085=Reactome:REACT_15518, GO:0005524=GO_REF:0000037, GO:0005829=Reactome:REACT_121163, GO:0006879=Reactome:REACT_25060, GO:0005739=GO_REF:0000019, GO:0033572=Reactome:REACT_25283, GO:0005902=GO_REF:0000019, GO:0016324=GO_REF:0000019, GO:0046961=GO_REF:0000002, GO:0005887=PMID:8463241, GO:0006810=PMID:8463241, GO:0015991=GO_REF:0000002, GO:0090382=Reactome:REACT_121256, GO:0015992=GO_REF:0000002} P38606 V-type proton ATPase catalytic subunit A protein 20100712 {GO:0008286=TAS, GO:0046034=IEA, GO:0051701=TAS, GO:0005886=ISS, GO:0016469=TAS, GO:0033180=IEA, GO:0055085=TAS, GO:0005524=IEA, GO:0005829=TAS, GO:0006879=TAS, GO:0005739=IEA, GO:0033572=TAS, GO:0005902=IEA, GO:0016324=IEA, GO:0046961=IEA, GO:0005887=TAS, GO:0006810=TAS, GO:0015991=IEA, GO:0090382=TAS, GO:0015992=IEA} ATP hydrolysis coupled proton transport, ATP metabolic process, cellular iron ion homeostasis, insulin receptor signaling pathway, interaction with host, phagosome maturation, proton transport, transferrin transport, transmembrane transport, transport apical plasma membrane, cytosol, integral to plasma membrane, microvillus, mitochondrion, plasma membrane, proton-transporting V-type ATPase, V1 domain, proton-transporting two-sector ATPase complex ATP binding, proton-transporting ATPase activity, rotational mechanism Human ATP6V1B1 Reactome UniProtKB {GO:0008286=Reactome:REACT_498, GO:0015078=PMID:14585495, GO:0007605=PMID:9916796, GO:0045851=PMID:19478356, GO:0033180=GO_REF:0000002, GO:0032403=GO_REF:0000019, GO:0006885=PMID:12414817, GO:0055074=PMID:19478356, GO:0005829=Reactome:REACT_121163, GO:0006879=Reactome:REACT_25060, GO:0033572=Reactome:REACT_25283, GO:0016323=PMID:14585495, GO:0016324=PMID:16928804, GO:0005737=PMID:14585495, GO:0016820=GO_REF:0000002, GO:0090382=Reactome:REACT_121256, GO:0033178=GO_REF:0000002, GO:0007588=PMID:12414817, GO:0046034=GO_REF:0000002, GO:0042472=PMID:19639346, GO:0051701=Reactome:REACT_121237, GO:0055085=Reactome:REACT_15518, GO:0016328=PMID:14585495, GO:0005524=GO_REF:0000002, GO:0012505=GO_REF:0000039, GO:0005902=PMID:14585495, GO:0001503=PMID:16433694, GO:0015991=GO_REF:0000002, GO:0016471=PMID:12414817, GO:0015992=PMID:12414817} P15313 V-type proton ATPase subunit B, kidney isoform protein 20130301 {GO:0008286=TAS, GO:0015078=ISS, GO:0007605=IMP, GO:0045851=IMP, GO:0033180=IEA, GO:0032403=IEA, GO:0006885=IMP, GO:0055074=IMP, GO:0005829=TAS, GO:0006879=TAS, GO:0033572=TAS, GO:0016323=ISS, GO:0016324=IDA, GO:0005737=ISS, GO:0016820=IEA, GO:0090382=TAS, GO:0033178=IEA, GO:0007588=IMP, GO:0046034=IEA, GO:0042472=IMP, GO:0051701=TAS, GO:0055085=TAS, GO:0016328=ISS, GO:0005524=IEA, GO:0012505=IEA, GO:0005902=ISS, GO:0001503=IMP, GO:0015991=IEA, GO:0016471=IMP, GO:0015992=IMP} ATP hydrolysis coupled proton transport, ATP metabolic process, calcium ion homeostasis, cellular iron ion homeostasis, excretion, inner ear morphogenesis, insulin receptor signaling pathway, interaction with host, ossification, pH reduction, phagosome maturation, proton transport, regulation of pH, sensory perception of sound, transferrin transport, transmembrane transport apical plasma membrane, basolateral plasma membrane, cytoplasm, cytosol, endomembrane system, lateral plasma membrane, microvillus, proton-transporting V-type ATPase, V1 domain, proton-transporting two-sector ATPase complex, catalytic domain, vacuolar proton-transporting V-type ATPase complex ATP binding, hydrogen ion transmembrane transporter activity, hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances, protein complex binding Human ATP6V1B2 HPA UniProtKB {GO:0008286=Reactome:REACT_498, GO:0042470=GO_REF:0000039, GO:0046034=GO_REF:0000002, GO:0005794=GO_REF:0000052, GO:0051701=Reactome:REACT_121237, GO:0005886=GO_REF:0000024, GO:0015078=PMID:2145275, GO:0033180=GO_REF:0000002, GO:0055085=Reactome:REACT_15518, GO:0005524=GO_REF:0000002, GO:0005829=Reactome:REACT_121163, GO:0043231=GO_REF:0000052, GO:0012505=GO_REF:0000039, GO:0006879=Reactome:REACT_25060, GO:0033572=Reactome:REACT_25283, GO:0005902=GO_REF:0000019, GO:0046961=PMID:2145275, GO:0015991=GO_REF:0000002, GO:0016820=GO_REF:0000002, GO:0016021=GO_REF:0000019, GO:0090382=Reactome:REACT_121256, GO:0015992=PMID:2145275, GO:0033178=GO_REF:0000002} P21281 V-type proton ATPase subunit B, brain isoform protein 20090616 {GO:0008286=TAS, GO:0042470=IEA, GO:0046034=IEA, GO:0005794=IDA, GO:0051701=TAS, GO:0005886=ISS, GO:0015078=TAS, GO:0033180=IEA, GO:0055085=TAS, GO:0005524=IEA, GO:0005829=TAS, GO:0043231=IDA, GO:0012505=IEA, GO:0006879=TAS, GO:0033572=TAS, GO:0005902=IEA, GO:0046961=TAS, GO:0015991=IEA, GO:0016820=IEA, GO:0016021=IEA, GO:0090382=TAS, GO:0015992=TAS, GO:0033178=IEA} ATP hydrolysis coupled proton transport, ATP metabolic process, cellular iron ion homeostasis, insulin receptor signaling pathway, interaction with host, phagosome maturation, proton transport, transferrin transport, transmembrane transport Golgi apparatus, cytosol, endomembrane system, integral to membrane, intracellular membrane-bounded organelle, melanosome, microvillus, plasma membrane, proton-transporting V-type ATPase, V1 domain, proton-transporting two-sector ATPase complex, catalytic domain ATP binding, hydrogen ion transmembrane transporter activity, hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances, proton-transporting ATPase activity, rotational mechanism Human ATP6V1C1 IntAct UniProtKB {GO:0005515=PMID:16415858, GO:0008286=Reactome:REACT_498, GO:0005215=PMID:8250920, GO:0051701=Reactome:REACT_121237, GO:0005886=GO_REF:0000024, GO:0016469=PMID:8250920, GO:0033180=GO_REF:0000002, GO:0045177=GO_REF:0000019, GO:0031410=GO_REF:0000019, GO:0055085=Reactome:REACT_15518, GO:0005829=Reactome:REACT_121163, GO:0006879=Reactome:REACT_25060, GO:0033572=Reactome:REACT_25283, GO:0008553=GO_REF:0000019, GO:0046961=PMID:8250920, GO:0015991=GO_REF:0000002, GO:0090382=Reactome:REACT_121256, GO:0015992=PMID:8250920} P21283 V-type proton ATPase subunit C 1 protein 20130415 {GO:0005515=IPI, GO:0008286=TAS, GO:0005215=NAS, GO:0051701=TAS, GO:0005886=ISS, GO:0016469=TAS, GO:0033180=IEA, GO:0045177=IEA, GO:0031410=IEA, GO:0055085=TAS, GO:0005829=TAS, GO:0006879=TAS, GO:0033572=TAS, GO:0008553=IEA, GO:0046961=TAS, GO:0015991=IEA, GO:0090382=TAS, GO:0015992=TAS} ATP hydrolysis coupled proton transport, cellular iron ion homeostasis, insulin receptor signaling pathway, interaction with host, phagosome maturation, proton transport, transferrin transport, transmembrane transport apical part of cell, cytoplasmic vesicle, cytosol, plasma membrane, proton-transporting V-type ATPase, V1 domain, proton-transporting two-sector ATPase complex hydrogen-exporting ATPase activity, phosphorylative mechanism, protein binding, proton-transporting ATPase activity, rotational mechanism, transporter activity Human UniProtKB:P62330 ATP6V1D Reactome UniProtKB {GO:0008286=Reactome:REACT_498, GO:0006879=Reactome:REACT_25060, GO:0005515=PMID:18752060, GO:0033572=Reactome:REACT_25283, GO:0051701=Reactome:REACT_121237, GO:0016020=PMID:18752060, GO:0042626=GO_REF:0000002, GO:0090382=Reactome:REACT_121256, GO:0055085=Reactome:REACT_15518, GO:0016471=PMID:18752060, GO:0005829=Reactome:REACT_121163, GO:0015992=GO_REF:0000037} Q9Y5K8 V-type proton ATPase subunit D protein 20100712 {GO:0008286=TAS, GO:0006879=TAS, GO:0005515=IPI, GO:0033572=TAS, GO:0051701=TAS, GO:0016020=IDA, GO:0042626=IEA, GO:0090382=TAS, GO:0055085=TAS, GO:0016471=IDA, GO:0005829=TAS, GO:0015992=IEA} cellular iron ion homeostasis, insulin receptor signaling pathway, interaction with host, phagosome maturation, proton transport, transferrin transport, transmembrane transport cytosol, membrane, vacuolar proton-transporting V-type ATPase complex ATPase activity, coupled to transmembrane movement of substances, protein binding Human ATP6V1E1 Reactome UniProtKB {GO:0008286=Reactome:REACT_498, GO:0005515=PMID:21784977, GO:0051701=Reactome:REACT_121237, GO:0016469=PMID:8250920, GO:0055085=Reactome:REACT_15518, GO:0005829=Reactome:REACT_121163, GO:0005739=GO_REF:0000019, GO:0006879=Reactome:REACT_25060, GO:0033572=Reactome:REACT_25283, GO:0005902=GO_REF:0000019, GO:0016324=GO_REF:0000024, GO:0008553=GO_REF:0000019, GO:0046961=GO_REF:0000002, GO:0015991=GO_REF:0000019, GO:0090382=Reactome:REACT_121256, GO:0005768=GO_REF:0000024, GO:0015992=PMID:8250920, GO:0033178=GO_REF:0000002} P36543 V-type proton ATPase subunit E 1 protein 20130301 {GO:0008286=TAS, GO:0005515=IPI, GO:0051701=TAS, GO:0016469=TAS, GO:0055085=TAS, GO:0005829=TAS, GO:0005739=IEA, GO:0006879=TAS, GO:0033572=TAS, GO:0005902=IEA, GO:0016324=ISS, GO:0008553=IEA, GO:0046961=IEA, GO:0015991=IEA, GO:0090382=TAS, GO:0005768=ISS, GO:0015992=TAS, GO:0033178=IEA} ATP hydrolysis coupled proton transport, cellular iron ion homeostasis, insulin receptor signaling pathway, interaction with host, phagosome maturation, proton transport, transferrin transport, transmembrane transport apical plasma membrane, cytosol, endosome, microvillus, mitochondrion, proton-transporting two-sector ATPase complex, proton-transporting two-sector ATPase complex, catalytic domain hydrogen-exporting ATPase activity, phosphorylative mechanism, protein binding, proton-transporting ATPase activity, rotational mechanism Human ATP6V1E2 Reactome UniProtKB {GO:0008286=Reactome:REACT_498, GO:0006879=Reactome:REACT_25060, GO:0033572=Reactome:REACT_25283, GO:0051701=Reactome:REACT_121237, GO:0008553=GO_REF:0000019, GO:0001669=GO_REF:0000019, GO:0046961=GO_REF:0000002, GO:0015991=GO_REF:0000019, GO:0090382=Reactome:REACT_121256, GO:0055085=Reactome:REACT_15518, GO:0005829=Reactome:REACT_121163, GO:0033178=GO_REF:0000002} Q96A05 V-type proton ATPase subunit E 2 protein 20130301 {GO:0008286=TAS, GO:0006879=TAS, GO:0033572=TAS, GO:0051701=TAS, GO:0008553=IEA, GO:0001669=IEA, GO:0046961=IEA, GO:0015991=IEA, GO:0090382=TAS, GO:0055085=TAS, GO:0005829=TAS, GO:0033178=IEA} ATP hydrolysis coupled proton transport, cellular iron ion homeostasis, insulin receptor signaling pathway, interaction with host, phagosome maturation, transferrin transport, transmembrane transport acrosomal vesicle, cytosol, proton-transporting two-sector ATPase complex, catalytic domain hydrogen-exporting ATPase activity, phosphorylative mechanism, proton-transporting ATPase activity, rotational mechanism Human ATP6V1F Reactome UniProtKB {GO:0005515=PMID:18752060, GO:0008286=Reactome:REACT_498, GO:0051701=Reactome:REACT_121237, GO:0015078=PMID:8581736, GO:0016469=PMID:8581736, GO:0033180=GO_REF:0000002, GO:0042624=PMID:8581736, GO:0055085=Reactome:REACT_15518, GO:0005829=Reactome:REACT_121163, GO:0006879=Reactome:REACT_25060, GO:0033572=Reactome:REACT_25283, GO:0016020=PMID:18752060, GO:0046961=GO_REF:0000002, GO:0015991=GO_REF:0000002, GO:0090382=Reactome:REACT_121256, GO:0016471=PMID:18752060, GO:0015992=PMID:8581736} Q16864 V-type proton ATPase subunit F protein 20130213 {GO:0005515=IPI, GO:0008286=TAS, GO:0051701=TAS, GO:0015078=NAS, GO:0016469=NAS, GO:0033180=IEA, GO:0042624=NAS, GO:0055085=TAS, GO:0005829=TAS, GO:0006879=TAS, GO:0033572=TAS, GO:0016020=IDA, GO:0046961=IEA, GO:0015991=IEA, GO:0090382=TAS, GO:0016471=IDA, GO:0015992=NAS} ATP hydrolysis coupled proton transport, cellular iron ion homeostasis, insulin receptor signaling pathway, interaction with host, phagosome maturation, proton transport, transferrin transport, transmembrane transport cytosol, membrane, proton-transporting V-type ATPase, V1 domain, proton-transporting two-sector ATPase complex, vacuolar proton-transporting V-type ATPase complex ATPase activity, uncoupled, hydrogen ion transmembrane transporter activity, protein binding, proton-transporting ATPase activity, rotational mechanism Human ATP6V1G1 Reactome UniProtKB {GO:0008286=Reactome:REACT_498, GO:0006879=Reactome:REACT_25060, GO:0033572=Reactome:REACT_25283, GO:0051701=Reactome:REACT_121237, GO:0005886=GO_REF:0000024, GO:0051117=PMID:17360703, GO:0016820=GO_REF:0000002, GO:0090382=Reactome:REACT_121256, GO:0055085=Reactome:REACT_15518, GO:0016471=GO_REF:0000002, GO:0005829=Reactome:REACT_121163, GO:0015992=GO_REF:0000037} O75348 V-type proton ATPase subunit G 1 protein 20130301 {GO:0008286=TAS, GO:0006879=TAS, GO:0033572=TAS, GO:0051701=TAS, GO:0005886=ISS, GO:0051117=IPI, GO:0016820=IEA, GO:0090382=TAS, GO:0055085=TAS, GO:0016471=IEA, GO:0005829=TAS, GO:0015992=IEA} cellular iron ion homeostasis, insulin receptor signaling pathway, interaction with host, phagosome maturation, proton transport, transferrin transport, transmembrane transport cytosol, plasma membrane, vacuolar proton-transporting V-type ATPase complex ATPase binding, hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances Human ATP6V1G2 Reactome UniProtKB {GO:0008286=Reactome:REACT_498, GO:0006879=Reactome:REACT_25060, GO:0033572=Reactome:REACT_25283, GO:0042470=GO_REF:0000039, GO:0051701=Reactome:REACT_121237, GO:0016820=GO_REF:0000002, GO:0090382=Reactome:REACT_121256, GO:0055085=Reactome:REACT_15518, GO:0016471=GO_REF:0000002, GO:0005829=Reactome:REACT_121163, GO:0015992=GO_REF:0000037} O95670 V-type proton ATPase subunit G 2 protein 20130301 {GO:0008286=TAS, GO:0006879=TAS, GO:0033572=TAS, GO:0042470=IEA, GO:0051701=TAS, GO:0016820=IEA, GO:0090382=TAS, GO:0055085=TAS, GO:0016471=IEA, GO:0005829=TAS, GO:0015992=IEA} cellular iron ion homeostasis, insulin receptor signaling pathway, interaction with host, phagosome maturation, proton transport, transferrin transport, transmembrane transport cytosol, melanosome, vacuolar proton-transporting V-type ATPase complex hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances Human ATP6V1H GOC UniProtKB {GO:0005515=PMID:9620685, GO:0008286=Reactome:REACT_498, GO:0006200=PMID:9442887, GO:0051701=Reactome:REACT_121237, GO:0005886=Reactome:REACT_11160, GO:0055085=Reactome:REACT_15518, GO:0050690=Reactome:REACT_11200, GO:0006897=PMID:12032142, GO:0005829=Reactome:REACT_121163, GO:0006879=Reactome:REACT_25060, GO:0033572=Reactome:REACT_25283, GO:0000221=PMID:9442887, GO:0050790=PMID:9442887, GO:0046961=GO_REF:0000002, GO:0007035=PMID:9442887, GO:0019048=GO_REF:0000037, GO:0015991=PMID:9442887, GO:0016032=Reactome:REACT_6185, GO:0030234=PMID:9442887, GO:0090382=Reactome:REACT_121256, GO:0016887=PMID:9442887} Q9UI12 V-type proton ATPase subunit H protein 20130413 {GO:0005515=IPI, GO:0008286=TAS, GO:0006200=NAS, GO:0051701=TAS, GO:0005886=TAS, GO:0055085=TAS, GO:0050690=TAS, GO:0006897=IDA, GO:0005829=TAS, GO:0006879=TAS, GO:0033572=TAS, GO:0000221=NAS, GO:0050790=NAS, GO:0046961=IEA, GO:0007035=NAS, GO:0019048=IEA, GO:0015991=NAS, GO:0016032=TAS, GO:0030234=NAS, GO:0090382=TAS, GO:0016887=NAS} ATP catabolic process, ATP hydrolysis coupled proton transport, cellular iron ion homeostasis, endocytosis, insulin receptor signaling pathway, interaction with host, phagosome maturation, regulation of catalytic activity, regulation of defense response to virus by virus, transferrin transport, transmembrane transport, vacuolar acidification, viral reproduction, virus-host interaction cytosol, plasma membrane, vacuolar proton-transporting V-type ATPase, V1 domain ATPase activity, enzyme regulator activity, protein binding, proton-transporting ATPase activity, rotational mechanism Human ATP7A Reactome UniProtKB {GO:0005515=PMID:16884690, GO:0005802=PMID:12812980, GO:0010468=GO_REF:0000019, GO:0051353=PMID:11092760, GO:0051216=GO_REF:0000024, GO:0031526=GO_REF:0000019, GO:0018205=GO_REF:0000024, GO:0051542=GO_REF:0000024, GO:0010043=GO_REF:0000019, GO:0021860=GO_REF:0000024, GO:0010041=GO_REF:0000019, GO:0031069=GO_REF:0000024, GO:0043524=GO_REF:0000019, GO:0034220=Reactome:REACT_25300, GO:0006878=PMID:16397091, GO:0030198=GO_REF:0000024, GO:0019430=GO_REF:0000024, GO:0030199=GO_REF:0000024, GO:0043025=GO_REF:0000024, GO:0060003=GO_REF:0000024, GO:0048251=GO_REF:0000024, GO:0032767=PMID:10497213, GO:0005794=PMID:9467005, GO:0048286=GO_REF:0000024, GO:0005507=PMID:15670166, GO:0043085=GO_REF:0000024, GO:0001701=GO_REF:0000019, GO:0048553=GO_REF:0000024, GO:0048554=GO_REF:0000024, GO:0006584=GO_REF:0000024, GO:0043588=GO_REF:0000024, GO:0007005=GO_REF:0000024, GO:0043005=GO_REF:0000024, GO:0048471=PMID:16397091, GO:0005886=Reactome:REACT_25071, GO:0005783=GO_REF:0000039, GO:0001836=GO_REF:0000019, GO:0005829=GO_REF:0000039, GO:0016323=PMID:16397091, GO:0042093=GO_REF:0000024, GO:0042415=GO_REF:0000024, GO:0042417=GO_REF:0000024, GO:0006570=GO_REF:0000019, GO:0005375=GO_REF:0000024, GO:0021702=GO_REF:0000024, GO:0015677=GO_REF:0000024, GO:0007626=GO_REF:0000024, GO:0030141=GO_REF:0000019, GO:0030140=PMID:9817923, GO:0042414=GO_REF:0000024, GO:0002082=GO_REF:0000024, GO:0001568=GO_REF:0000024, GO:0005770=PMID:8943055, GO:0021954=GO_REF:0000024, GO:0016532=GO_REF:0000024, GO:0055085=Reactome:REACT_15518, GO:0005524=PMID:9817923, GO:0004008=GO_REF:0000024, GO:0010273=GO_REF:0000024, GO:0042428=GO_REF:0000024, GO:0048813=GO_REF:0000019, GO:0001974=GO_REF:0000024, GO:0048812=GO_REF:0000024, GO:0043473=GO_REF:0000024, GO:0042421=GO_REF:0000019, GO:0016021=GO_REF:0000019, GO:0006825=PMID:11092760, GO:0006568=GO_REF:0000024} Q04656 Copper-transporting ATPase 1 protein 20130301 {GO:0005515=IPI, GO:0005802=IDA, GO:0010468=IEA, GO:0051353=IDA, GO:0051216=ISS, GO:0031526=IEA, GO:0018205=ISS, GO:0051542=ISS, GO:0010043=IEA, GO:0021860=ISS, GO:0010041=IEA, GO:0031069=ISS, GO:0043524=IEA, GO:0034220=TAS, GO:0006878=IMP, GO:0030198=ISS, GO:0019430=ISS, GO:0030199=ISS, GO:0043025=ISS, GO:0060003=ISS, GO:0048251=ISS, GO:0032767=IPI, GO:0005794=IDA, GO:0048286=ISS, GO:0005507=IDA, GO:0043085=ISS, GO:0001701=IEA, GO:0048553=ISS, GO:0048554=ISS, GO:0006584=ISS, GO:0043588=ISS, GO:0007005=ISS, GO:0043005=ISS, GO:0048471=IDA, GO:0005886=TAS, GO:0005783=IEA, GO:0001836=IEA, GO:0005829=IEA, GO:0016323=IDA, GO:0042093=ISS, GO:0042415=ISS, GO:0042417=ISS, GO:0006570=IEA, GO:0005375=ISS, GO:0021702=ISS, GO:0015677=ISS, GO:0007626=ISS, GO:0030141=IEA, GO:0030140=IMP, GO:0042414=ISS, GO:0002082=ISS, GO:0001568=ISS, GO:0005770=IDA, GO:0021954=ISS, GO:0016532=ISS, GO:0055085=TAS, GO:0005524=TAS, GO:0004008=ISS, GO:0010273=ISS, GO:0042428=ISS, GO:0048813=IEA, GO:0001974=ISS, GO:0048812=ISS, GO:0043473=ISS, GO:0042421=IEA, GO:0016021=IEA, GO:0006825=IMP, GO:0006568=ISS} T-helper cell differentiation, blood vessel development, blood vessel remodeling, cartilage development, catecholamine metabolic process, cellular copper ion homeostasis, central nervous system neuron development, cerebellar Purkinje cell differentiation, collagen fibril organization, copper ion export, copper ion import, copper ion transport, dendrite morphogenesis, detoxification of copper ion, dopamine metabolic process, elastic fiber assembly, elastin biosynthetic process, epinephrine metabolic process, extracellular matrix organization, hair follicle morphogenesis, in utero embryonic development, ion transmembrane transport, locomotory behavior, lung alveolus development, mitochondrion organization, negative regulation of metalloenzyme activity, negative regulation of neuron apoptotic process, neuron projection morphogenesis, norepinephrine biosynthetic process, norepinephrine metabolic process, peptidyl-lysine modification, pigmentation, positive regulation of catalytic activity, positive regulation of metalloenzyme activity, positive regulation of oxidoreductase activity, pyramidal neuron development, regulation of gene expression, regulation of oxidative phosphorylation, release of cytochrome c from mitochondria, removal of superoxide radicals, response to iron(III) ion, response to zinc ion, serotonin metabolic process, skin development, transmembrane transport, tryptophan metabolic process, tyrosine metabolic process Golgi apparatus, basolateral plasma membrane, brush border membrane, cytosol, endoplasmic reticulum, integral to membrane, late endosome, neuron projection, neuronal cell body, perinuclear region of cytoplasm, plasma membrane, secretory granule, trans-Golgi network, trans-Golgi network transport vesicle ATP binding, copper ion binding, copper ion transmembrane transporter activity, copper-dependent protein binding, copper-exporting ATPase activity, protein binding, superoxide dismutase copper chaperone activity Human ATP7B Reactome UniProtKB {GO:0005802=PMID:15269005, GO:0005515=PMID:16554302, GO:0048471=PMID:16939419, GO:0006882=GO_REF:0000019, GO:0046872=GO_REF:0000002, GO:0015680=GO_REF:0000019, GO:0005739=GO_REF:0000039, GO:0016323=PMID:15269005, GO:0006878=PMID:16554302, GO:0034220=Reactome:REACT_25300, GO:0000166=GO_REF:0000002, GO:0015677=PMID:16472602, GO:0051208=PMID:16472602, GO:0005507=PMID:14709553, GO:0005770=PMID:15681833, GO:0055085=Reactome:REACT_15518, GO:0005524=PMID:15205462, GO:0004008=PMID:12763797, GO:0019829=GO_REF:0000002, GO:0007595=GO_REF:0000019, GO:0000139=Reactome:REACT_24963, GO:0005887=PMID:8298641, GO:0016023=PMID:16472602, GO:0016021=GO_REF:0000038, GO:0046688=PMID:15269005, GO:0006825=PMID:12572677} P35670 Copper-transporting ATPase 2 protein 20130301 {GO:0005802=IDA, GO:0005515=IPI, GO:0048471=IDA, GO:0006882=IEA, GO:0046872=IEA, GO:0015680=IEA, GO:0005739=IEA, GO:0016323=IDA, GO:0006878=TAS, GO:0034220=TAS, GO:0000166=IEA, GO:0015677=IDA, GO:0051208=IDA, GO:0005507=IDA, GO:0005770=IDA, GO:0055085=TAS, GO:0005524=IDA, GO:0004008=NAS, GO:0019829=IEA, GO:0007595=IEA, GO:0000139=TAS, GO:0005887=TAS, GO:0016023=IDA, GO:0016021=IEA, GO:0046688=IDA, GO:0006825=IGI} cellular copper ion homeostasis, cellular zinc ion homeostasis, copper ion import, copper ion transport, intracellular copper ion transport, ion transmembrane transport, lactation, response to copper ion, sequestering of calcium ion, transmembrane transport Golgi membrane, basolateral plasma membrane, cytoplasmic membrane-bounded vesicle, integral to membrane, integral to plasma membrane, late endosome, mitochondrion, perinuclear region of cytoplasm, trans-Golgi network ATP binding, cation-transporting ATPase activity, copper ion binding, copper-exporting ATPase activity, metal ion binding, nucleotide binding, protein binding Human ATP8A1 Reactome UniProtKB {GO:0005515=PMID:21914794, GO:0015247=GO_REF:0000029, GO:0000287=GO_REF:0000002, GO:0005886=Reactome:REACT_115892, GO:0005783=PMID:21914794, GO:0055085=Reactome:REACT_15518, GO:0005524=GO_REF:0000029, GO:0045332=PMID:21914794, GO:0019829=PMID:10198212, GO:0034220=Reactome:REACT_25300, GO:0042584=GO_REF:0000039, GO:0004012=GO_REF:0000003, GO:0016021=GO_REF:0000029, GO:0015917=GO_REF:0000029} Q9Y2Q0 Probable phospholipid-transporting ATPase IA protein 20130301 {GO:0005515=IPI, GO:0015247=NAS, GO:0000287=IEA, GO:0005886=TAS, GO:0005783=IDA, GO:0055085=TAS, GO:0005524=NAS, GO:0045332=NAS, GO:0019829=NAS, GO:0034220=TAS, GO:0042584=IEA, GO:0004012=IEA, GO:0016021=NAS, GO:0015917=NAS} aminophospholipid transport, ion transmembrane transport, phospholipid translocation, transmembrane transport chromaffin granule membrane, endoplasmic reticulum, integral to membrane, plasma membrane ATP binding, aminophospholipid transporter activity, cation-transporting ATPase activity, magnesium ion binding, phospholipid-translocating ATPase activity, protein binding Human ATP8A2 PINC UniProtKB {GO:0019829=GO_REF:0000002, GO:0008285=PMID:10551800, GO:0000287=GO_REF:0000002, GO:0004012=GO_REF:0000003, GO:0016021=GO_REF:0000037, GO:0005524=GO_REF:0000037, GO:0031175=GO_REF:0000019} Q9NTI2 Probable phospholipid-transporting ATPase IB protein 20050308 {GO:0019829=IEA, GO:0008285=TAS, GO:0000287=IEA, GO:0004012=IEA, GO:0016021=IEA, GO:0005524=IEA, GO:0031175=IEA} negative regulation of cell proliferation, neuron projection development integral to membrane ATP binding, cation-transporting ATPase activity, magnesium ion binding, phospholipid-translocating ATPase activity Human ATP8B2 GOC UniProtKB {GO:0019829=GO_REF:0000002, GO:0034220=Reactome:REACT_25300, GO:0000287=GO_REF:0000002, GO:0006200=PMID:12880872, GO:0005886=Reactome:REACT_115892, GO:0004012=GO_REF:0000003, GO:0016021=PMID:12880872, GO:0055085=Reactome:REACT_15518, GO:0016887=PMID:12880872, GO:0005524=GO_REF:0000037} P98198 Probable phospholipid-transporting ATPase ID protein 20130413 {GO:0019829=IEA, GO:0034220=TAS, GO:0000287=IEA, GO:0006200=RCA, GO:0005886=TAS, GO:0004012=IEA, GO:0016021=RCA, GO:0055085=TAS, GO:0016887=RCA, GO:0005524=IEA} ATP catabolic process, ion transmembrane transport, transmembrane transport integral to membrane, plasma membrane ATP binding, ATPase activity, cation-transporting ATPase activity, magnesium ion binding, phospholipid-translocating ATPase activity Human ATP8B3 GOC UniProtKB {GO:0019829=GO_REF:0000002, GO:0000287=GO_REF:0000002, GO:0006200=PMID:12880872, GO:0001669=GO_REF:0000019, GO:0004012=GO_REF:0000003, GO:0016021=PMID:12880872, GO:0007339=GO_REF:0000019, GO:0016887=PMID:12880872, GO:0005524=GO_REF:0000037, GO:0045332=GO_REF:0000019} O60423 Probable phospholipid-transporting ATPase IK protein 20130413 {GO:0019829=IEA, GO:0000287=IEA, GO:0006200=RCA, GO:0001669=IEA, GO:0004012=IEA, GO:0016021=RCA, GO:0007339=IEA, GO:0016887=RCA, GO:0005524=IEA, GO:0045332=IEA} ATP catabolic process, binding of sperm to zona pellucida, phospholipid translocation acrosomal vesicle, integral to membrane ATP binding, ATPase activity, cation-transporting ATPase activity, magnesium ion binding, phospholipid-translocating ATPase activity Human ATP9A UniProtKB UniProtKB {GO:0005802=PMID:21914794, GO:0019829=GO_REF:0000002, GO:0048471=PMID:21914794, GO:0005794=GO_REF:0000039, GO:0000287=GO_REF:0000002, GO:0031901=GO_REF:0000039, GO:0004012=GO_REF:0000003, GO:0016021=GO_REF:0000037, GO:0055037=PMID:21914794, GO:0005524=GO_REF:0000037, GO:0045332=PMID:21914794, GO:0005769=PMID:21914794} O75110 Probable phospholipid-transporting ATPase IIA protein 20110922 {GO:0005802=IDA, GO:0019829=IEA, GO:0048471=IDA, GO:0005794=IEA, GO:0000287=IEA, GO:0031901=IEA, GO:0004012=IEA, GO:0016021=IEA, GO:0055037=IDA, GO:0005524=IEA, GO:0045332=NAS, GO:0005769=IDA} phospholipid translocation Golgi apparatus, early endosome, early endosome membrane, integral to membrane, perinuclear region of cytoplasm, recycling endosome, trans-Golgi network ATP binding, cation-transporting ATPase activity, magnesium ion binding, phospholipid-translocating ATPase activity Human ATP9B UniProtKB UniProtKB {GO:0005802=PMID:21914794, GO:0019829=GO_REF:0000029, GO:0048471=PMID:21914794, GO:0015247=GO_REF:0000029, GO:0005794=GO_REF:0000039, GO:0000287=GO_REF:0000002, GO:0004012=GO_REF:0000003, GO:0072600=PMID:21914794, GO:0015917=GO_REF:0000029, GO:0016021=GO_REF:0000029, GO:0005524=GO_REF:0000029, GO:0045332=PMID:21914794} O43861 Probable phospholipid-transporting ATPase IIB protein 20110922 {GO:0005802=IDA, GO:0019829=NAS, GO:0048471=IDA, GO:0015247=NAS, GO:0005794=IEA, GO:0000287=IEA, GO:0004012=IEA, GO:0072600=IMP, GO:0015917=NAS, GO:0016021=NAS, GO:0005524=NAS, GO:0045332=NAS} aminophospholipid transport, establishment of protein localization to Golgi, phospholipid translocation Golgi apparatus, integral to membrane, perinuclear region of cytoplasm, trans-Golgi network ATP binding, aminophospholipid transporter activity, cation-transporting ATPase activity, magnesium ion binding, phospholipid-translocating ATPase activity Human ATPAF1 UniProtKB UniProtKB {GO:0005515=PMID:11410595, GO:0005739=GO_REF:0000039, GO:0006461=GO_REF:0000002} Q5TC12 ATP synthase mitochondrial F1 complex assembly factor 1 protein 20091116 {GO:0005515=IPI, GO:0005739=IEA, GO:0006461=IEA} protein complex assembly mitochondrion protein binding Human UniProtKB:P06576 ATPAF2 LIFEdb UniProtKB {GO:0005515=PMID:11410595, GO:0005739=GO_REF:0000039, GO:0016607=GO_REF:0000054, GO:0043461=PMID:14757859} Q8N5M1 ATP synthase mitochondrial F1 complex assembly factor 2 protein 20100607 {GO:0005515=IPI, GO:0005739=IEA, GO:0016607=IDA, GO:0043461=NAS} proton-transporting ATP synthase complex assembly mitochondrion, nuclear speck protein binding Human ATPBD4 UniProtKB UniProtKB {GO:0017178=PMID:23169644, GO:0005524=GO_REF:0000037, GO:0017183=PMID:23169644} Q7L8W6 Diphthine--ammonia ligase protein 20130118 {GO:0017178=TAS, GO:0005524=IEA, GO:0017183=TAS} peptidyl-diphthamide biosynthetic process from peptidyl-histidine ATP binding, diphthine-ammonia ligase activity Human ATPIF1 HPA UniProtKB {GO:0004857=PMID:10664857, GO:0005516=GO_REF:0000024, GO:0009986=PMID:15528193, GO:0051346=GO_REF:0000024, GO:0072593=GO_REF:0000019, GO:0045980=GO_REF:0000002, GO:0042030=PMID:12110673, GO:0042981=GO_REF:0000019, GO:0006091=PMID:10664857, GO:0001525=PMID:15528193, GO:0042803=GO_REF:0000024, GO:0006783=PMID:23135403, GO:0005753=PMID:12110673, GO:0005739=GO_REF:0000052, GO:0001937=PMID:15528193, GO:0043532=PMID:15528193, GO:0051289=GO_REF:0000024, GO:0030218=PMID:23135403, GO:0051117=PMID:15528193, GO:0051260=GO_REF:0000024} Q9UII2 ATPase inhibitor, mitochondrial protein 20101115 {GO:0004857=TAS, GO:0005516=ISS, GO:0009986=IDA, GO:0051346=ISS, GO:0072593=IEA, GO:0045980=IEA, GO:0042030=IDA, GO:0042981=IEA, GO:0006091=TAS, GO:0001525=TAS, GO:0042803=ISS, GO:0006783=IMP, GO:0005753=IDA, GO:0005739=IDA, GO:0001937=IDA, GO:0043532=IDA, GO:0051289=ISS, GO:0030218=IMP, GO:0051117=IDA, GO:0051260=ISS} angiogenesis, erythrocyte differentiation, generation of precursor metabolites and energy, heme biosynthetic process, negative regulation of endothelial cell proliferation, negative regulation of hydrolase activity, negative regulation of nucleotide metabolic process, protein homooligomerization, protein homotetramerization, reactive oxygen species metabolic process, regulation of apoptotic process cell surface, mitochondrial proton-transporting ATP synthase complex, mitochondrion ATPase binding, ATPase inhibitor activity, angiostatin binding, calmodulin binding, enzyme inhibitor activity, protein homodimerization activity Human ATR BHF-UCL UniProtKB {GO:0005515=PMID:20810650, GO:0032407=PMID:16713580, GO:0032405=PMID:16713580, GO:0071480=PMID:9925639, GO:0034644=PMID:9925639, GO:0046777=PMID:9733515, GO:0018105=PMID:9733515, GO:0016301=GO_REF:0000038, GO:0016773=GO_REF:0000002, GO:0001741=GO_REF:0000019, GO:0005694=GO_REF:0000024, GO:0043393=GO_REF:0000019, GO:0007275=PMID:9590286, GO:0003677=GO_REF:0000037, GO:0005524=GO_REF:0000037, GO:0006974=PMID:15538388, GO:0006260=Reactome:REACT_6769, GO:0007049=PMID:9590286, GO:0004672=PMID:14657349, GO:0006281=Reactome:REACT_216, GO:0004674=PMID:9733515, GO:0016605=GO_REF:0000039, GO:0043517=PMID:9925639, GO:0000075=Reactome:REACT_1538, GO:0005654=Reactome:REACT_18335, GO:0008156=PMID:14657349, GO:0000077=PMID:14657349, GO:0090399=PMID:15149599} Q13535 Serine/threonine-protein kinase ATR protein 20110209 {GO:0005515=IPI, GO:0032407=IDA, GO:0032405=IDA, GO:0071480=IDA, GO:0034644=IMP, GO:0046777=IDA, GO:0018105=IDA, GO:0016301=IEA, GO:0016773=IEA, GO:0001741=IEA, GO:0005694=ISS, GO:0043393=IEA, GO:0007275=TAS, GO:0003677=IEA, GO:0005524=IEA, GO:0006974=TAS, GO:0006260=TAS, GO:0007049=TAS, GO:0004672=IDA, GO:0006281=TAS, GO:0004674=IDA, GO:0016605=IEA, GO:0043517=IMP, GO:0000075=TAS, GO:0005654=TAS, GO:0008156=IMP, GO:0000077=IDA, GO:0090399=IMP} DNA damage checkpoint, DNA repair, DNA replication, cell cycle, cell cycle checkpoint, cellular response to UV, cellular response to gamma radiation, multicellular organismal development, negative regulation of DNA replication, peptidyl-serine phosphorylation, positive regulation of DNA damage response, signal transduction by p53 class mediator, protein autophosphorylation, regulation of protein binding, replicative senescence, response to DNA damage stimulus PML body, XY body, chromosome, nucleoplasm ATP binding, DNA binding, MutLalpha complex binding, MutSalpha complex binding, kinase activity, phosphotransferase activity, alcohol group as acceptor, protein binding, protein kinase activity, protein serine/threonine kinase activity Human ATRIP Reactome UniProtKB {GO:0006260=Reactome:REACT_6769, GO:0005515=PMID:14657349, GO:0006281=GO_REF:0000037, GO:0000075=Reactome:REACT_1538, GO:0005654=Reactome:REACT_6939, GO:0000077=PMID:14657349} Q8WXE1 ATR-interacting protein protein 20130213 {GO:0006260=TAS, GO:0005515=IPI, GO:0006281=IEA, GO:0000075=TAS, GO:0005654=TAS, GO:0000077=TAS} DNA damage checkpoint, DNA repair, DNA replication, cell cycle checkpoint nucleoplasm protein binding Human ATRN PINC UniProtKB {GO:0005737=GO_REF:0000019, GO:0006954=GO_REF:0000037, GO:0005886=PMID:9736737, GO:0005887=PMID:10086356, GO:0040014=GO_REF:0000019, GO:0030246=GO_REF:0000002, GO:0004872=GO_REF:0000019, GO:0005615=PMID:17261078, GO:0006979=GO_REF:0000019} O75882 Attractin protein 20030904 {GO:0005737=IEA, GO:0006954=IEA, GO:0005886=NAS, GO:0005887=TAS, GO:0040014=IEA, GO:0030246=IEA, GO:0004872=IEA, GO:0005615=IDA, GO:0006979=IEA} inflammatory response, regulation of multicellular organism growth, response to oxidative stress cytoplasm, extracellular space, integral to plasma membrane, plasma membrane carbohydrate binding, receptor activity Human ATRNL1 ENSEMBL UniProtKB {GO:0007186=GO_REF:0000019, GO:0030246=GO_REF:0000002, GO:0016021=GO_REF:0000037} Q5VV63 Attractin-like protein 1 protein 20130413 {GO:0007186=IEA, GO:0030246=IEA, GO:0016021=IEA} G-protein coupled receptor signaling pathway integral to membrane carbohydrate binding Human Ensembl:ENSMUSP00000076514 ATRX GOC UniProtKB {GO:0005515=PMID:12953102, GO:0006355=PMID:7697714, GO:0070087=PMID:15882967, GO:0004386=PMID:7874112, GO:0005634=PMID:7874112, GO:0006310=PMID:7697714, GO:0003677=GO_REF:0000037, GO:0005524=GO_REF:0000037, GO:0003678=PMID:7697714, GO:0006306=PMID:10742099, GO:0005720=PMID:10570185, GO:0006281=GO_REF:0000037, GO:0003682=GO_REF:0000019, GO:0008270=GO_REF:0000002, GO:0032508=PMID:7697714, GO:0030900=GO_REF:0000019} P46100 Transcriptional regulator ATRX protein 20130413 {GO:0005515=IPI, GO:0006355=TAS, GO:0070087=IPI, GO:0004386=TAS, GO:0005634=TAS, GO:0006310=TAS, GO:0003677=IEA, GO:0005524=IEA, GO:0003678=TAS, GO:0006306=TAS, GO:0005720=TAS, GO:0006281=IEA, GO:0003682=IEA, GO:0008270=IEA, GO:0032508=TAS, GO:0030900=IEA} DNA duplex unwinding, DNA methylation, DNA recombination, DNA repair, forebrain development, regulation of transcription, DNA-dependent nuclear heterochromatin, nucleus ATP binding, DNA binding, DNA helicase activity, chromatin binding, chromo shadow domain binding, helicase activity, protein binding, zinc ion binding Human ATXN1 HPA UniProtKB {GO:0005515=PMID:23275563, GO:0008344=GO_REF:0000019, GO:0008219=GO_REF:0000037, GO:0005634=GO_REF:0000052, GO:0043621=PMID:9097953, GO:0016363=PMID:9353120, GO:0043231=GO_REF:0000052, GO:0042802=PMID:16713569, GO:0008266=PMID:11136710, GO:0005737=GO_REF:0000052, GO:0045944=GO_REF:0000019, GO:0042272=PMID:15615787, GO:0051168=PMID:15615787, GO:0006396=PMID:15615787, GO:0060079=GO_REF:0000019, GO:0005730=GO_REF:0000052, GO:0008022=PMID:15016912, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037, GO:0042326=GO_REF:0000019, GO:0034046=PMID:11136710, GO:0043569=GO_REF:0000019, GO:0008542=GO_REF:0000019, GO:0005654=PMID:12757932, GO:0045892=PMID:15016912, GO:0042405=PMID:15615787} P54253 Ataxin-1 protein 20080818 {GO:0005515=IPI, GO:0008344=IEA, GO:0008219=IEA, GO:0005634=IDA, GO:0043621=IDA, GO:0016363=IDA, GO:0043231=IDA, GO:0042802=IPI, GO:0008266=IDA, GO:0005737=IDA, GO:0045944=IEA, GO:0042272=IDA, GO:0051168=IDA, GO:0006396=NAS, GO:0060079=IEA, GO:0005730=IDA, GO:0008022=IPI, GO:0003677=IEA, GO:0006351=IEA, GO:0042326=IEA, GO:0034046=IDA, GO:0043569=IEA, GO:0008542=IEA, GO:0005654=IDA, GO:0045892=IDA, GO:0042405=IDA} RNA processing, adult locomotory behavior, cell death, negative regulation of insulin-like growth factor receptor signaling pathway, negative regulation of phosphorylation, negative regulation of transcription, DNA-dependent, nuclear export, positive regulation of transcription from RNA polymerase II promoter, regulation of excitatory postsynaptic membrane potential, transcription, DNA-dependent, visual learning cytoplasm, intracellular membrane-bounded organelle, nuclear RNA export factor complex, nuclear inclusion body, nuclear matrix, nucleolus, nucleoplasm, nucleus DNA binding, identical protein binding, poly(G) RNA binding, poly(U) RNA binding, protein C-terminus binding, protein binding, protein self-association Human ATXN10 LIFEdb UniProtKB {GO:0005515=PMID:21565611, GO:0008219=GO_REF:0000037, GO:0048471=PMID:16498633, GO:0005737=GO_REF:0000054, GO:0043025=PMID:15201271, GO:0031175=PMID:16498633, GO:0030425=PMID:15201271, GO:0007399=PMID:16385455, GO:0042802=GO_REF:0000019, GO:0005829=GO_REF:0000019} Q9UBB4 Ataxin-10 protein 20100607 {GO:0005515=IPI, GO:0008219=IEA, GO:0048471=IDA, GO:0005737=IDA, GO:0043025=IDA, GO:0031175=IDA, GO:0030425=IDA, GO:0007399=IMP, GO:0042802=IEA, GO:0005829=IEA} cell death, nervous system development, neuron projection development cytoplasm, cytosol, dendrite, neuronal cell body, perinuclear region of cytoplasm identical protein binding, protein binding Human ATXN1L UniProtKB UniProtKB {GO:0006355=GO_REF:0000037, GO:0003723=GO_REF:0000002, GO:0005634=GO_REF:0000039, GO:0003677=GO_REF:0000037, GO:0030425=GO_REF:0000039, GO:0006351=GO_REF:0000037} P0C7T5 Ataxin-1-like protein 20130413 {GO:0006355=IEA, GO:0003723=IEA, GO:0005634=IEA, GO:0003677=IEA, GO:0030425=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent dendrite, nucleus DNA binding, RNA binding Human UniProtKB-SubCell:SL-0283 ATXN2 HPA UniProtKB {GO:0005515=PMID:23209657, GO:0008219=GO_REF:0000037, GO:0005154=PMID:18602463, GO:0048471=PMID:17097639, GO:0005794=PMID:12812977, GO:0033962=PMID:17392519, GO:0016070=PMID:15663938, GO:0010494=PMID:17392519, GO:0003723=PMID:10814712, GO:0005730=GO_REF:0000052, GO:0050658=PMID:10814712, GO:0005634=GO_REF:0000052, GO:0008022=PMID:15663938, GO:0006417=PMID:16835262, GO:0048872=GO_REF:0000019, GO:0050905=GO_REF:0000019, GO:0034063=PMID:17392519, GO:0005737=GO_REF:0000052, GO:0040015=GO_REF:0000019, GO:0021702=GO_REF:0000019, GO:0030529=PMID:16835262, GO:0048812=GO_REF:0000019, GO:0005844=PMID:16835262, GO:0002091=PMID:18602463} Q99700 Ataxin-2 protein 20100326 {GO:0005515=IPI, GO:0008219=IEA, GO:0005154=IPI, GO:0048471=IDA, GO:0005794=IDA, GO:0033962=IMP, GO:0016070=NAS, GO:0010494=IDA, GO:0003723=NAS, GO:0005730=IDA, GO:0050658=NAS, GO:0005634=IDA, GO:0008022=IPI, GO:0006417=NAS, GO:0048872=IEA, GO:0050905=IEA, GO:0034063=IMP, GO:0005737=IDA, GO:0040015=IEA, GO:0021702=IEA, GO:0030529=IDA, GO:0048812=IEA, GO:0005844=IDA, GO:0002091=IMP} RNA metabolic process, RNA transport, cell death, cerebellar Purkinje cell differentiation, cytoplasmic mRNA processing body assembly, homeostasis of number of cells, negative regulation of multicellular organism growth, negative regulation of receptor internalization, neuromuscular process, neuron projection morphogenesis, regulation of translation, stress granule assembly Golgi apparatus, cytoplasm, cytoplasmic stress granule, nucleolus, nucleus, perinuclear region of cytoplasm, polysome, ribonucleoprotein complex RNA binding, epidermal growth factor receptor binding, protein C-terminus binding, protein binding Human ATXN2L IntAct UniProtKB {GO:0005515=PMID:23209657, GO:0008150=GO_REF:0000015, GO:0003674=GO_REF:0000015, GO:0034063=PMID:23209657, GO:0016020=PMID:11784712, GO:0016607=PMID:23209657, GO:0010494=PMID:23209657, GO:0010603=PMID:23209657} Q8WWM7 Ataxin-2-like protein protein 20130415 {GO:0005515=IPI, GO:0008150=ND, GO:0003674=ND, GO:0034063=IMP, GO:0016020=IDA, GO:0016607=IDA, GO:0010494=IDA, GO:0010603=IDA} biological_process, regulation of cytoplasmic mRNA processing body assembly, stress granule assembly cytoplasmic stress granule, membrane, nuclear speck molecular_function, protein binding Human UniProtKB:Q13283 ATXN3 IntAct UniProtKB {GO:0005515=PMID:16713569, GO:0008219=GO_REF:0000037, GO:0030036=PMID:20637808, GO:0004843=GO_REF:0000024, GO:0045104=PMID:20637808, GO:0010810=PMID:20637808, GO:0007268=PMID:7655453, GO:0016363=GO_REF:0000039, GO:0034605=GO_REF:0000019, GO:0005737=PMID:9124802, GO:0005759=GO_REF:0000019, GO:0035520=GO_REF:0000024, GO:0008242=GO_REF:0000002, GO:0035640=GO_REF:0000019, GO:0031625=GO_REF:0000024, GO:0071218=GO_REF:0000024, GO:0070932=GO_REF:0000019, GO:0006355=GO_REF:0000037, GO:0031966=GO_REF:0000019, GO:0000226=PMID:20637808, GO:0006351=GO_REF:0000037, GO:0007399=PMID:9124802, GO:0005654=PMID:9580663, GO:0006515=GO_REF:0000024, GO:0043161=GO_REF:0000024, GO:0004221=GO_REF:0000024, GO:0006289=PMID:10915768, GO:0001012=GO_REF:0000019, GO:0042405=GO_REF:0000019} P54252 Ataxin-3 protein 20130415 {GO:0005515=IPI, GO:0008219=IEA, GO:0030036=IMP, GO:0004843=ISS, GO:0045104=IMP, GO:0010810=IMP, GO:0007268=TAS, GO:0016363=IEA, GO:0034605=IEA, GO:0005737=TAS, GO:0005759=IEA, GO:0035520=ISS, GO:0008242=IEA, GO:0035640=IEA, GO:0031625=ISS, GO:0071218=ISS, GO:0070932=IEA, GO:0006355=IEA, GO:0031966=IEA, GO:0000226=IMP, GO:0006351=IEA, GO:0007399=TAS, GO:0005654=TAS, GO:0006515=ISS, GO:0043161=ISS, GO:0004221=ISS, GO:0006289=TAS, GO:0001012=IEA, GO:0042405=IEA} actin cytoskeleton organization, cell death, cellular response to heat, cellular response to misfolded protein, exploration behavior, histone H3 deacetylation, intermediate filament cytoskeleton organization, microtubule cytoskeleton organization, misfolded or incompletely synthesized protein catabolic process, monoubiquitinated protein deubiquitination, nervous system development, nucleotide-excision repair, proteasomal ubiquitin-dependent protein catabolic process, regulation of cell-substrate adhesion, regulation of transcription, DNA-dependent, synaptic transmission, transcription, DNA-dependent cytoplasm, mitochondrial matrix, mitochondrial membrane, nuclear inclusion body, nuclear matrix, nucleoplasm RNA polymerase II regulatory region DNA binding, omega peptidase activity, protein binding, ubiquitin protein ligase binding, ubiquitin thiolesterase activity, ubiquitin-specific protease activity Human UniProtKB:Q9BSU1 ATXN3L UniProtKB UniProtKB {GO:0016579=PMID:21118805, GO:0006355=GO_REF:0000037, GO:0004843=PMID:21118805, GO:0006508=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0008242=GO_REF:0000002, GO:0006351=GO_REF:0000037} Q9H3M9 Putative ataxin-3-like protein protein 20110218 {GO:0016579=IDA, GO:0006355=IEA, GO:0004843=IDA, GO:0006508=IEA, GO:0005634=IEA, GO:0008242=IEA, GO:0006351=IEA} protein deubiquitination, proteolysis, regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus omega peptidase activity, ubiquitin-specific protease activity Human ATXN7 HPA UniProtKB {GO:0005515=PMID:21078624, GO:0008219=GO_REF:0000037, GO:0016578=PMID:18206972, GO:0006997=PMID:10441328, GO:0005730=GO_REF:0000052, GO:0000226=PMID:22100762, GO:0005634=GO_REF:0000052, GO:0006351=GO_REF:0000037, GO:0016363=GO_REF:0000039, GO:0042326=GO_REF:0000019, GO:0005737=GO_REF:0000052, GO:0043569=GO_REF:0000019, GO:0003682=GO_REF:0000019, GO:0045944=GO_REF:0000019, GO:0015630=PMID:22100762, GO:0007601=PMID:9288099} O15265 Ataxin-7 protein 20101115 {GO:0005515=IPI, GO:0008219=IEA, GO:0016578=IDA, GO:0006997=TAS, GO:0005730=IDA, GO:0000226=IMP, GO:0005634=IDA, GO:0006351=IEA, GO:0016363=IEA, GO:0042326=IEA, GO:0005737=IDA, GO:0043569=IEA, GO:0003682=IEA, GO:0045944=IEA, GO:0015630=IDA, GO:0007601=TAS} cell death, histone deubiquitination, microtubule cytoskeleton organization, negative regulation of insulin-like growth factor receptor signaling pathway, negative regulation of phosphorylation, nucleus organization, positive regulation of transcription from RNA polymerase II promoter, transcription, DNA-dependent, visual perception cytoplasm, microtubule cytoskeleton, nuclear matrix, nucleolus, nucleus chromatin binding, protein binding Human ATXN7L1 null null {} null null null null {} null null null ATXN7L2 null null {} null null null null {} null null null ATXN7L3 UniProtKB UniProtKB {GO:0005515=PMID:18206972, GO:0016578=PMID:18206972, GO:0030374=PMID:18206972, GO:0000124=PMID:18206972, GO:0003713=PMID:18206972, GO:0045893=PMID:18206972, GO:0046872=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q14CW9 Ataxin-7-like protein 3 protein 20090427 {GO:0005515=IPI, GO:0016578=IDA, GO:0030374=IDA, GO:0000124=IDA, GO:0003713=IDA, GO:0045893=IDA, GO:0046872=IEA, GO:0006351=IEA} histone deubiquitination, positive regulation of transcription, DNA-dependent, transcription, DNA-dependent SAGA complex ligand-dependent nuclear receptor transcription coactivator activity, metal ion binding, protein binding, transcription coactivator activity Human ATXN7L3B null null {} null null null null {} null null null AUH Reactome UniProtKB {GO:0005739=GO_REF:0000024, GO:0034641=Reactome:REACT_13, GO:0005759=Reactome:REACT_1157, GO:0004490=Reactome:REACT_1157, GO:0009083=Reactome:REACT_197, GO:0044281=Reactome:REACT_111217, GO:0003730=PMID:7892223, GO:0004300=PMID:7892223, GO:0006402=PMID:7892223, GO:0003824=GO_REF:0000002, GO:0006552=GO_REF:0000041} Q13825 Methylglutaconyl-CoA hydratase, mitochondrial protein 20100211 {GO:0005739=ISS, GO:0034641=TAS, GO:0005759=TAS, GO:0004490=EXP, GO:0009083=TAS, GO:0044281=TAS, GO:0003730=IDA, GO:0004300=IDA, GO:0006402=IDA, GO:0003824=IEA, GO:0006552=IEA} branched-chain amino acid catabolic process, cellular nitrogen compound metabolic process, leucine catabolic process, mRNA catabolic process, small molecule metabolic process mitochondrial matrix, mitochondrion catalytic activity, enoyl-CoA hydratase activity, mRNA 3'-UTR binding, methylglutaconyl-CoA hydratase activity Human AUP1 HPA UniProtKB {GO:0005783=GO_REF:0000052, GO:0005730=GO_REF:0000052, GO:0005789=GO_REF:0000039, GO:0005634=GO_REF:0000052, GO:0016021=GO_REF:0000037, GO:0043231=GO_REF:0000052} Q9Y679 Ancient ubiquitous protein 1 protein 20110516 {GO:0005783=IDA, GO:0005730=IDA, GO:0005789=IEA, GO:0005634=IDA, GO:0016021=IEA, GO:0043231=IDA} endoplasmic reticulum, endoplasmic reticulum membrane, integral to membrane, intracellular membrane-bounded organelle, nucleolus, nucleus Human AURKA ENSEMBL UniProtKB {GO:0005515=PMID:19801554, GO:0048471=PMID:20531406, GO:0005634=PMID:20531406, GO:0031145=Reactome:REACT_6828, GO:0005829=Reactome:REACT_6974, GO:0046777=PMID:19774610, GO:0031647=PMID:15987997, GO:0005876=PMID:19801554, GO:0007051=PMID:15504738, GO:0031625=GO_REF:0000019, GO:0005813=PMID:21399614, GO:0019901=PMID:18615013, GO:0048015=PMID:15504738, GO:0005819=PMID:19774610, GO:0030496=PMID:19774610, GO:0045840=PMID:19774610, GO:0046605=PMID:19774610, GO:0005524=GO_REF:0000002, GO:0007049=PMID:15504738, GO:0007067=GO_REF:0000037, GO:0004672=PMID:19801554, GO:0004674=GO_REF:0000002, GO:0030030=GO_REF:0000037, GO:0004712=PMID:19774610, GO:0006468=PMID:9153231, GO:0031616=PMID:19801554, GO:0000278=GO_REF:0000019, GO:0051301=GO_REF:0000037} Q5QPD4 Aurora kinase A protein 20130413 {GO:0005515=IPI, GO:0048471=IDA, GO:0005634=IDA, GO:0031145=TAS, GO:0005829=TAS, GO:0046777=TAS, GO:0031647=IMP, GO:0005876=IDA, GO:0007051=NAS, GO:0031625=IEA, GO:0005813=IDA, GO:0019901=IPI, GO:0048015=NAS, GO:0005819=TAS, GO:0030496=TAS, GO:0045840=TAS, GO:0046605=TAS, GO:0005524=IEA, GO:0007049=NAS, GO:0007067=IEA, GO:0004672=IDA, GO:0004674=IEA, GO:0030030=IEA, GO:0004712=TAS, GO:0006468=TAS, GO:0031616=IDA, GO:0000278=IEA, GO:0051301=IEA} anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process, cell cycle, cell division, cell projection organization, mitosis, mitotic cell cycle, phosphatidylinositol-mediated signaling, positive regulation of mitosis, protein autophosphorylation, protein phosphorylation, regulation of centrosome cycle, regulation of protein stability, spindle organization centrosome, cytosol, midbody, nucleus, perinuclear region of cytoplasm, spindle, spindle microtubule, spindle pole centrosome ATP binding, protein binding, protein kinase activity, protein kinase binding, protein serine/threonine kinase activity, protein serine/threonine/tyrosine kinase activity, ubiquitin protein ligase binding Human Ensembl:ENSMUSP00000028997 AURKAIP1 HPA UniProtKB {GO:0005739=GO_REF:0000052, GO:0005515=PMID:12244051, GO:0045839=PMID:12244051, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0045862=PMID:12244051, GO:0043231=GO_REF:0000052} Q9NWT8 Aurora kinase A-interacting protein protein 20101115 {GO:0005739=IDA, GO:0005515=IPI, GO:0045839=NAS, GO:0005730=IDA, GO:0005634=IDA, GO:0045862=IDA, GO:0043231=IDA} negative regulation of mitosis, positive regulation of proteolysis intracellular membrane-bounded organelle, mitochondrion, nucleolus, nucleus protein binding Human AURKB BHF-UCL UniProtKB {GO:0005515=PMID:22939624, GO:0051256=PMID:16103226, GO:0000236=Reactome:REACT_682, GO:0008283=GO_REF:0000019, GO:0034501=PMID:19468067, GO:0005634=PMID:20959462, GO:0031145=Reactome:REACT_6828, GO:0046872=GO_REF:0000037, GO:0005829=Reactome:REACT_150414, GO:0036089=PMID:16103226, GO:0000910=GO_REF:0000019, GO:0034644=PMID:20959462, GO:0046777=PMID:19774610, GO:0002903=PMID:20959462, GO:0000087=Reactome:REACT_910, GO:0000780=PMID:18195732, GO:0010369=GO_REF:0000019, GO:0007568=GO_REF:0000019, GO:0005819=PMID:19774610, GO:0051983=PMID:19774610, GO:0030496=PMID:19774610, GO:0016570=PMID:19774610, GO:0000122=PMID:20959462, GO:0005524=GO_REF:0000037, GO:0032133=PMID:19774610, GO:0007049=GO_REF:0000019, GO:0004672=GO_REF:0000019, GO:0004674=GO_REF:0000037, GO:0000779=PMID:19465021, GO:0004712=PMID:19774610, GO:0000278=Reactome:REACT_152, GO:0008608=PMID:19774610, GO:0000090=Reactome:REACT_1275} Q96GD4 Aurora kinase B protein 20100107 {GO:0005515=IPI, GO:0051256=IMP, GO:0000236=TAS, GO:0008283=IEA, GO:0034501=IMP, GO:0005634=IDA, GO:0031145=TAS, GO:0046872=IEA, GO:0005829=TAS, GO:0036089=IDA, GO:0000910=IEA, GO:0034644=IDA, GO:0046777=TAS, GO:0002903=IDA, GO:0000087=TAS, GO:0000780=IDA, GO:0010369=IEA, GO:0007568=IEA, GO:0005819=TAS, GO:0051983=TAS, GO:0030496=TAS, GO:0016570=TAS, GO:0000122=IDA, GO:0005524=IEA, GO:0032133=TAS, GO:0007049=IEA, GO:0004672=IEA, GO:0004674=IEA, GO:0000779=IDA, GO:0004712=TAS, GO:0000278=TAS, GO:0008608=TAS, GO:0000090=TAS} M phase of mitotic cell cycle, aging, anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process, attachment of spindle microtubules to kinetochore, cell cycle, cell proliferation, cellular response to UV, cleavage furrow formation, cytokinesis, histone modification, mitotic anaphase, mitotic cell cycle, mitotic prometaphase, negative regulation of B cell apoptotic process, negative regulation of transcription from RNA polymerase II promoter, protein autophosphorylation, protein localization to kinetochore, regulation of chromosome segregation, spindle midzone assembly involved in mitosis chromocenter, chromosome passenger complex, condensed chromosome, centromeric region, condensed nuclear chromosome, centromeric region, cytosol, midbody, nucleus, spindle ATP binding, metal ion binding, protein binding, protein kinase activity, protein serine/threonine kinase activity, protein serine/threonine/tyrosine kinase activity Human AURKC PINC UniProtKB {GO:0051256=PMID:19774610, GO:0000793=PMID:15670791, GO:0005819=PMID:19774610, GO:0016570=PMID:19774610, GO:0030496=PMID:19774610, GO:0005634=GO_REF:0000039, GO:0051233=PMID:15670791, GO:0005524=GO_REF:0000037, GO:0000910=PMID:10066797, GO:0032133=PMID:19774610, GO:0005737=GO_REF:0000037, GO:0004672=PMID:15670791, GO:0007126=GO_REF:0000037, GO:0004674=GO_REF:0000037, GO:0004712=PMID:19774610, GO:0006468=PMID:15670791, GO:0008608=PMID:19774610, GO:0000775=GO_REF:0000039} Q9UQB9 Aurora kinase C protein 20050308 {GO:0051256=TAS, GO:0000793=IDA, GO:0005819=TAS, GO:0016570=TAS, GO:0030496=TAS, GO:0005634=IEA, GO:0051233=IDA, GO:0005524=IEA, GO:0000910=TAS, GO:0032133=TAS, GO:0005737=IEA, GO:0004672=IDA, GO:0007126=IEA, GO:0004674=IEA, GO:0004712=TAS, GO:0006468=IDA, GO:0008608=TAS, GO:0000775=IEA} attachment of spindle microtubules to kinetochore, cytokinesis, histone modification, meiosis, protein phosphorylation, spindle midzone assembly involved in mitosis chromosome passenger complex, chromosome, centromeric region, condensed chromosome, cytoplasm, midbody, nucleus, spindle, spindle midzone ATP binding, protein kinase activity, protein serine/threonine kinase activity, protein serine/threonine/tyrosine kinase activity Human AUTS2 UniProtKB UniProtKB {GO:0008150=GO_REF:0000015, GO:0003674=GO_REF:0000015, GO:0005575=GO_REF:0000015} Q8WXX7 Autism susceptibility gene 2 protein protein 20061026 {GO:0008150=ND, GO:0003674=ND, GO:0005575=ND} biological_process cellular_component molecular_function Human AVEN UniProtKB UniProtKB {GO:0005622=PMID:10949025, GO:0005515=PMID:10949025, GO:0043066=PMID:10949025, GO:0016020=PMID:10949025, GO:0006915=GO_REF:0000037, GO:0012505=GO_REF:0000039} Q9NQS1 Cell death regulator Aven protein 20040128 {GO:0005622=IDA, GO:0005515=IPI, GO:0043066=IDA, GO:0016020=IDA, GO:0006915=IEA, GO:0012505=IEA} apoptotic process, negative regulation of apoptotic process endomembrane system, intracellular, membrane protein binding Human AVIL PINC UniProtKB {GO:0043005=GO_REF:0000024, GO:0030424=GO_REF:0000039, GO:0005737=GO_REF:0000037, GO:0060271=PMID:20393563, GO:0007010=GO_REF:0000002, GO:0010976=GO_REF:0000024, GO:0006950=GO_REF:0000019, GO:0003779=GO_REF:0000024, GO:0042995=GO_REF:0000024, GO:0015629=PMID:9664034, GO:0007399=PMID:9664034, GO:0051693=GO_REF:0000037} O75366 Advillin protein 20030904 {GO:0043005=ISS, GO:0030424=IEA, GO:0005737=IEA, GO:0060271=IMP, GO:0007010=IEA, GO:0010976=ISS, GO:0006950=IEA, GO:0003779=ISS, GO:0042995=ISS, GO:0015629=TAS, GO:0007399=TAS, GO:0051693=IEA} actin filament capping, cilium morphogenesis, cytoskeleton organization, nervous system development, positive regulation of neuron projection development, response to stress actin cytoskeleton, axon, cell projection, cytoplasm, neuron projection actin binding Human AVL9 UniProtKB UniProtKB {GO:0016477=PMID:22595670, GO:0016021=GO_REF:0000037, GO:0055037=PMID:22595670} Q8NBF6 Late secretory pathway protein AVL9 homolog protein 20121001 {GO:0016477=IDA, GO:0016021=IEA, GO:0055037=IDA} cell migration integral to membrane, recycling endosome Human AVP GOC UniProtKB {GO:0030307=GO_REF:0000019, GO:0006091=PMID:1740104, GO:0051970=GO_REF:0000019, GO:0005615=GO_REF:0000019, GO:0003084=GO_REF:0000019, GO:0006833=Reactome:REACT_24023, GO:0070371=PMID:18402937, GO:0005184=PMID:1740104, GO:0005185=GO_REF:0000002, GO:0043027=PMID:18402937, GO:0031394=GO_REF:0000019, GO:0042538=GO_REF:0000019, GO:0043084=GO_REF:0000019, GO:0002125=GO_REF:0000019, GO:0035176=GO_REF:0000019, GO:0035813=GO_REF:0000019, GO:0007621=GO_REF:0000019, GO:0008284=GO_REF:0000019, GO:0045471=GO_REF:0000019, GO:0030819=GO_REF:0000019, GO:0007267=PMID:1740104, GO:0031894=PMID:18402937, GO:0043252=Reactome:REACT_23988, GO:0031895=GO_REF:0000019, GO:0007204=GO_REF:0000019, GO:0030425=GO_REF:0000019, GO:0005829=Reactome:REACT_23822, GO:0014049=GO_REF:0000019, GO:0033138=PMID:18402937, GO:0045907=GO_REF:0000019, GO:0090201=PMID:18402937, GO:0042310=GO_REF:0000037, GO:0007626=GO_REF:0000019, GO:0007625=GO_REF:0000019, GO:0004871=PMID:18402937, GO:0030141=GO_REF:0000019, GO:0043154=PMID:18402937, GO:0042711=GO_REF:0000019, GO:0043066=PMID:18402937, GO:0005102=PMID:1740104, GO:0032849=GO_REF:0000019, GO:0005576=Reactome:REACT_23926, GO:0055085=Reactome:REACT_19118, GO:0070528=PMID:18402937, GO:0010628=PMID:18538351, GO:0007165=PMID:18402937, GO:0004672=PMID:18402937, GO:0050891=GO_REF:0000019, GO:0006468=PMID:18402937, GO:0035094=GO_REF:0000019} P01185 Vasopressin-neurophysin 2-copeptin protein 20130413 {GO:0030307=IEA, GO:0006091=TAS, GO:0051970=IEA, GO:0005615=IEA, GO:0003084=IEA, GO:0006833=TAS, GO:0070371=IDA, GO:0005184=TAS, GO:0005185=IEA, GO:0043027=IDA, GO:0031394=IEA, GO:0042538=IEA, GO:0043084=IEA, GO:0002125=IEA, GO:0035176=IEA, GO:0035813=IEA, GO:0007621=IEA, GO:0008284=IEA, GO:0045471=IEA, GO:0030819=IEA, GO:0007267=TAS, GO:0031894=IPI, GO:0043252=TAS, GO:0031895=IEA, GO:0007204=IEA, GO:0030425=IEA, GO:0005829=TAS, GO:0014049=IEA, GO:0033138=IDA, GO:0045907=IEA, GO:0090201=IDA, GO:0042310=IEA, GO:0007626=IEA, GO:0007625=IEA, GO:0004871=IDA, GO:0030141=IEA, GO:0043154=IDA, GO:0042711=IEA, GO:0043066=IDA, GO:0005102=TAS, GO:0032849=IEA, GO:0005576=TAS, GO:0055085=TAS, GO:0070528=IDA, GO:0010628=IDA, GO:0007165=IDA, GO:0004672=IDA, GO:0050891=IEA, GO:0006468=IDA, GO:0035094=IEA} ERK1 and ERK2 cascade, cell-cell signaling, elevation of cytosolic calcium ion concentration, generation of precursor metabolites and energy, grooming behavior, hyperosmotic salinity response, locomotory behavior, maternal aggressive behavior, maternal behavior, multicellular organismal water homeostasis, negative regulation of apoptotic process, negative regulation of cysteine-type endopeptidase activity involved in apoptotic process, negative regulation of female receptivity, negative regulation of release of cytochrome c from mitochondria, negative regulation of transmission of nerve impulse, penile erection, positive regulation of cAMP biosynthetic process, positive regulation of cell growth, positive regulation of cell proliferation, positive regulation of cellular pH reduction, positive regulation of gene expression, positive regulation of glutamate secretion, positive regulation of peptidyl-serine phosphorylation, positive regulation of prostaglandin biosynthetic process, positive regulation of systemic arterial blood pressure, positive regulation of vasoconstriction, protein kinase C signaling cascade, protein phosphorylation, regulation of renal sodium excretion, response to ethanol, response to nicotine, signal transduction, social behavior, sodium-independent organic anion transport, transmembrane transport, vasoconstriction, water transport cytosol, dendrite, extracellular region, extracellular space, secretory granule V1A vasopressin receptor binding, V1B vasopressin receptor binding, cysteine-type endopeptidase inhibitor activity involved in apoptotic process, neurohypophyseal hormone activity, neuropeptide hormone activity, protein kinase activity, receptor binding, signal transducer activity Human AVPI1 ENSEMBL UniProtKB {GO:0000187=GO_REF:0000019, GO:0007049=GO_REF:0000037} Q5T686 Arginine vasopressin-induced protein 1 protein 20130413 {GO:0000187=IEA, GO:0007049=IEA} activation of MAPK activity, cell cycle Human Ensembl:ENSMUSP00000018965 AVPR1A Reactome UniProtKB {GO:0005515=PMID:18402937, GO:0008284=GO_REF:0000019, GO:0019722=GO_REF:0000019, GO:0005886=Reactome:REACT_22436, GO:0030307=GO_REF:0000019, GO:0008015=PMID:8106369, GO:0031894=GO_REF:0000019, GO:0006091=PMID:8106369, GO:0007202=PMID:8106369, GO:0051970=GO_REF:0000019, GO:0007204=GO_REF:0000019, GO:0021537=GO_REF:0000019, GO:0001992=GO_REF:0000019, GO:0014049=GO_REF:0000019, GO:0003084=GO_REF:0000019, GO:0045907=GO_REF:0000019, GO:0005000=GO_REF:0000002, GO:0005080=PMID:10858434, GO:0007625=GO_REF:0000019, GO:0051412=GO_REF:0000019, GO:0042631=GO_REF:0000019, GO:0042711=GO_REF:0000019, GO:0014902=GO_REF:0000019, GO:0031394=GO_REF:0000019, GO:0032849=GO_REF:0000019, GO:0043084=GO_REF:0000019, GO:0031410=GO_REF:0000019, GO:0042713=GO_REF:0000019, GO:0002125=GO_REF:0000019, GO:0007186=PMID:10858434, GO:0005887=PMID:8838314, GO:0035176=GO_REF:0000019, GO:0035815=GO_REF:0000019, GO:0007621=GO_REF:0000019, GO:0010460=GO_REF:0000019, GO:0016021=GO_REF:0000002, GO:0017046=GO_REF:0000019, GO:0005768=PMID:10858434} P37288 Vasopressin V1a receptor protein 20081212 {GO:0005515=IPI, GO:0008284=IEA, GO:0019722=IEA, GO:0005886=TAS, GO:0030307=IEA, GO:0008015=TAS, GO:0031894=IEA, GO:0006091=TAS, GO:0007202=TAS, GO:0051970=IEA, GO:0007204=IEA, GO:0021537=IEA, GO:0001992=IEA, GO:0014049=IEA, GO:0003084=IEA, GO:0045907=IEA, GO:0005000=IEA, GO:0005080=TAS, GO:0007625=IEA, GO:0051412=IEA, GO:0042631=IEA, GO:0042711=IEA, GO:0014902=IEA, GO:0031394=IEA, GO:0032849=IEA, GO:0043084=IEA, GO:0031410=IEA, GO:0042713=IEA, GO:0002125=IEA, GO:0007186=TAS, GO:0005887=TAS, GO:0035176=IEA, GO:0035815=IEA, GO:0007621=IEA, GO:0010460=IEA, GO:0016021=IEA, GO:0017046=IEA, GO:0005768=TAS} G-protein coupled receptor signaling pathway, activation of phospholipase C activity, blood circulation, calcium-mediated signaling, cellular response to water deprivation, elevation of cytosolic calcium ion concentration, generation of precursor metabolites and energy, grooming behavior, maternal aggressive behavior, maternal behavior, myotube differentiation, negative regulation of female receptivity, negative regulation of transmission of nerve impulse, penile erection, positive regulation of cell growth, positive regulation of cell proliferation, positive regulation of cellular pH reduction, positive regulation of glutamate secretion, positive regulation of heart rate, positive regulation of prostaglandin biosynthetic process, positive regulation of renal sodium excretion, positive regulation of systemic arterial blood pressure, positive regulation of vasoconstriction, regulation of systemic arterial blood pressure by vasopressin, response to corticosterone stimulus, social behavior, sperm ejaculation, telencephalon development cytoplasmic vesicle, endosome, integral to membrane, integral to plasma membrane, plasma membrane V1A vasopressin receptor binding, peptide hormone binding, protein binding, protein kinase C binding, vasopressin receptor activity Human AVPR1B Reactome UniProtKB {GO:0005886=Reactome:REACT_22436, GO:0007186=PMID:10858434, GO:0005887=PMID:7805841, GO:0005000=GO_REF:0000002, GO:0005080=PMID:10858434, GO:0007202=PMID:7805841, GO:0007204=PMID:7929452, GO:0001992=GO_REF:0000019, GO:0005768=PMID:10858434} P47901 Vasopressin V1b receptor protein 20081212 {GO:0005886=TAS, GO:0007186=TAS, GO:0005887=TAS, GO:0005000=IEA, GO:0005080=TAS, GO:0007202=TAS, GO:0007204=TAS, GO:0001992=IEA, GO:0005768=TAS} G-protein coupled receptor signaling pathway, activation of phospholipase C activity, elevation of cytosolic calcium ion concentration, regulation of systemic arterial blood pressure by vasopressin endosome, integral to plasma membrane, plasma membrane protein kinase C binding, vasopressin receptor activity Human AVPR2 BHF-UCL UniProtKB {GO:0007588=PMID:1303257, GO:0008284=GO_REF:0000019, GO:0005794=PMID:10880054, GO:0005886=Reactome:REACT_23926, GO:0005783=PMID:10880054, GO:0007249=GO_REF:0000019, GO:0055085=Reactome:REACT_15518, GO:0021537=GO_REF:0000019, GO:0007599=PMID:10880054, GO:0010628=GO_REF:0000024, GO:0007190=PMID:9224808, GO:0003084=GO_REF:0000019, GO:0005887=PMID:1303257, GO:0005000=PMID:8882880, GO:0031398=PMID:19372219, GO:0035814=GO_REF:0000019, GO:0007188=PMID:10880054, GO:0006833=Reactome:REACT_24023, GO:0016021=PMID:8882880, GO:0035811=GO_REF:0000019, GO:0032609=GO_REF:0000019, GO:0034097=GO_REF:0000019, GO:0005768=PMID:10858434} P30518 Vasopressin V2 receptor protein 20120316 {GO:0007588=TAS, GO:0008284=IEA, GO:0005794=TAS, GO:0005886=TAS, GO:0005783=TAS, GO:0007249=IEA, GO:0055085=TAS, GO:0021537=IEA, GO:0007599=TAS, GO:0010628=ISS, GO:0007190=TAS, GO:0003084=IEA, GO:0005887=TAS, GO:0005000=TAS, GO:0031398=NAS, GO:0035814=IEA, GO:0007188=TAS, GO:0006833=TAS, GO:0016021=NAS, GO:0035811=IEA, GO:0032609=IEA, GO:0034097=IEA, GO:0005768=TAS} I-kappaB kinase/NF-kappaB cascade, activation of adenylate cyclase activity, adenylate cyclase-modulating G-protein coupled receptor signaling pathway, excretion, hemostasis, interferon-gamma production, negative regulation of renal sodium excretion, negative regulation of urine volume, positive regulation of cell proliferation, positive regulation of gene expression, positive regulation of protein ubiquitination, positive regulation of systemic arterial blood pressure, response to cytokine stimulus, telencephalon development, transmembrane transport, water transport Golgi apparatus, endoplasmic reticulum, endosome, integral to membrane, integral to plasma membrane, plasma membrane vasopressin receptor activity Human AXIN1 GOC UniProtKB {GO:0005515=PMID:10644691, GO:0008219=GO_REF:0000033, GO:0008013=PMID:16890161, GO:0045599=GO_REF:0000033, GO:0007605=GO_REF:0000019, GO:0030877=PMID:16188939, GO:0046330=GO_REF:0000024, GO:0038032=GO_REF:0000002, GO:0046332=PMID:18593713, GO:0031122=GO_REF:0000033, GO:0043621=GO_REF:0000019, GO:0043623=PMID:16601693, GO:0042803=GO_REF:0000024, GO:0042802=GO_REF:0000024, GO:0005622=GO_REF:0000002, GO:0030163=GO_REF:0000019, GO:0021797=GO_REF:0000033, GO:0031398=PMID:18593713, GO:0051443=PMID:16601693, GO:0051260=GO_REF:0000019, GO:0005938=GO_REF:0000033, GO:0031625=PMID:16601693, GO:0000209=GO_REF:0000019, GO:0010800=PMID:18593713, GO:0030910=GO_REF:0000033, GO:0001743=GO_REF:0000033, GO:0019901=GO_REF:0000024, GO:0014069=GO_REF:0000033, GO:0007275=GO_REF:0000002, GO:0001701=GO_REF:0000019, GO:0051248=GO_REF:0000019, GO:0043547=GO_REF:0000033, GO:0060823=GO_REF:0000033, GO:0060272=GO_REF:0000033, GO:0045893=PMID:16601693, GO:0019899=PMID:21478859, GO:0021881=GO_REF:0000033, GO:0070016=GO_REF:0000024, GO:0005881=GO_REF:0000033, GO:0048471=PMID:19038973, GO:0045732=PMID:9601641, GO:0007368=GO_REF:0000033, GO:0005886=PMID:16890161, GO:0030178=PMID:10644691, GO:0032436=GO_REF:0000019, GO:0005634=PMID:12072559, GO:0090244=GO_REF:0000033, GO:0009950=GO_REF:0000033, GO:0035412=GO_REF:0000033, GO:0071944=PMID:19038973, GO:0005829=Reactome:REACT_10134, GO:0032147=PMID:9601641, GO:0002039=PMID:15526030, GO:0033138=PMID:18593713, GO:0005737=PMID:17569865, GO:0071514=GO_REF:0000019, GO:0004871=PMID:9601641, GO:0034244=GO_REF:0000019, GO:0060070=PMID:9601641, GO:0090090=GO_REF:0000033, GO:0030511=GO_REF:0000019, GO:0048048=GO_REF:0000033, GO:0070411=PMID:16601693, GO:0006915=GO_REF:0000037, GO:0070412=GO_REF:0000019, GO:0031410=GO_REF:0000024, GO:0007257=GO_REF:0000033, GO:0008022=GO_REF:0000019, GO:0016328=PMID:12072559, GO:0036342=GO_REF:0000019, GO:0006913=GO_REF:0000019, GO:2000060=GO_REF:0000024, GO:0032947=PMID:9601641, GO:0071407=GO_REF:0000033, GO:0001934=PMID:9601641, GO:0016023=GO_REF:0000033, GO:0055001=GO_REF:0000033, GO:0005096=GO_REF:0000033, GO:0048320=GO_REF:0000033} O15169 Axin-1 protein 20130413 {GO:0005515=IPI, GO:0008219=IBA, GO:0008013=IPI, GO:0045599=IBA, GO:0007605=IEA, GO:0030877=IDA, GO:0046330=ISS, GO:0038032=IEA, GO:0046332=IPI, GO:0031122=IBA, GO:0043621=IEA, GO:0043623=IDA, GO:0042803=ISS, GO:0042802=ISS, GO:0005622=IEA, GO:0030163=IEA, GO:0021797=IBA, GO:0031398=IDA, GO:0051443=IMP, GO:0051260=IEA, GO:0005938=IBA, GO:0031625=IPI, GO:0000209=IEA, GO:0010800=IDA, GO:0030910=IBA, GO:0001743=IBA, GO:0019901=ISS, GO:0014069=IBA, GO:0007275=IEA, GO:0001701=IEA, GO:0051248=IEA, GO:0043547=IBA, GO:0060823=IBA, GO:0060272=IBA, GO:0045893=IMP, GO:0019899=IPI, GO:0021881=IBA, GO:0070016=ISS, GO:0005881=IBA, GO:0048471=IDA, GO:0045732=IDA, GO:0007368=IBA, GO:0005886=IDA, GO:0030178=IDA, GO:0032436=IEA, GO:0005634=IDA, GO:0090244=IBA, GO:0009950=IBA, GO:0035412=IBA, GO:0071944=IDA, GO:0005829=TAS, GO:0032147=IDA, GO:0002039=IDA, GO:0033138=IDA, GO:0005737=IDA, GO:0071514=IEA, GO:0004871=IDA, GO:0034244=IEA, GO:0060070=IC, GO:0090090=IBA, GO:0030511=IEA, GO:0048048=IBA, GO:0070411=IPI, GO:0006915=IEA, GO:0070412=IEA, GO:0031410=ISS, GO:0007257=IBA, GO:0008022=IEA, GO:0016328=IDA, GO:0036342=IEA, GO:0006913=IEA, GO:2000060=ISS, GO:0032947=IDA, GO:0071407=IBA, GO:0001934=IDA, GO:0016023=IBA, GO:0055001=IBA, GO:0005096=IBA, GO:0048320=IBA} Wnt receptor signaling pathway involved in forebrain neuron fate commitment, Wnt receptor signaling pathway involved in somitogenesis, activation of JUN kinase activity, activation of protein kinase activity, apoptotic process, axial mesoderm formation, canonical Wnt receptor signaling pathway, canonical Wnt receptor signaling pathway involved in neural plate anterior/posterior pattern formation, cell death, cellular protein complex assembly, cellular response to organic cyclic compound, cytoplasmic microtubule organization, determination of left/right symmetry, dorsal/ventral axis specification, embryonic eye morphogenesis, embryonic skeletal joint morphogenesis, forebrain anterior/posterior pattern specification, genetic imprinting, in utero embryonic development, multicellular organismal development, muscle cell development, negative regulation of Wnt receptor signaling pathway, negative regulation of canonical Wnt receptor signaling pathway, negative regulation of fat cell differentiation, negative regulation of protein metabolic process, negative regulation of transcription elongation from RNA polymerase II promoter, nucleocytoplasmic transport, olfactory placode formation, optic placode formation, positive regulation of GTPase activity, positive regulation of JNK cascade, positive regulation of peptidyl-serine phosphorylation, positive regulation of peptidyl-threonine phosphorylation, positive regulation of proteasomal ubiquitin-dependent protein catabolic process, positive regulation of protein catabolic process, positive regulation of protein phosphorylation, positive regulation of protein ubiquitination, positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process, positive regulation of transcription, DNA-dependent, positive regulation of transforming growth factor beta receptor signaling pathway, positive regulation of ubiquitin-protein ligase activity, post-anal tail morphogenesis, protein catabolic process, protein homooligomerization, protein polyubiquitination, regulation of catenin import into nucleus, sensory perception of sound, termination of G-protein coupled receptor signaling pathway beta-catenin destruction complex, cell cortex, cell periphery, cytoplasm, cytoplasmic membrane-bounded vesicle, cytoplasmic microtubule, cytoplasmic vesicle, cytosol, intracellular, lateral plasma membrane, nucleus, perinuclear region of cytoplasm, plasma membrane, postsynaptic density GTPase activator activity, I-SMAD binding, R-SMAD binding, SMAD binding, armadillo repeat domain binding, beta-catenin binding, enzyme binding, identical protein binding, p53 binding, protein C-terminus binding, protein binding, protein complex scaffold, protein homodimerization activity, protein kinase binding, protein self-association, signal transducer activity, ubiquitin protein ligase binding Human PANTHER:PTN000090250 AXIN2 GOC UniProtKB {GO:0008219=GO_REF:0000019, GO:0005881=GO_REF:0000033, GO:0008285=PMID:16247484, GO:0008013=PMID:11017067, GO:0005886=GO_REF:0000033, GO:0008283=GO_REF:0000019, GO:0003413=GO_REF:0000019, GO:0001756=GO_REF:0000019, GO:0030877=PMID:11017067, GO:0010718=PMID:17072303, GO:0038032=GO_REF:0000002, GO:0005634=PMID:12072559, GO:0030282=GO_REF:0000019, GO:0090244=GO_REF:0000033, GO:0035414=PMID:11017067, GO:0009950=GO_REF:0000033, GO:0005622=GO_REF:0000002, GO:2000054=GO_REF:0000019, GO:0005737=PMID:21383061, GO:0045860=GO_REF:0000019, GO:0042476=PMID:15042511, GO:0048255=PMID:17072303, GO:0004871=GO_REF:0000002, GO:0090090=PMID:11017067, GO:0010942=PMID:16247484, GO:0005938=GO_REF:0000033, GO:0031625=PMID:21478859, GO:0070602=PMID:20300119, GO:0005813=PMID:20300119, GO:0019901=GO_REF:0000033, GO:0061181=GO_REF:0000019, GO:0014069=GO_REF:0000033, GO:0070411=GO_REF:0000019, GO:0007275=GO_REF:0000002, GO:0032423=PMID:11017067, GO:0043570=PMID:18755497, GO:0043547=GO_REF:0000033, GO:0043234=GO_REF:0000019, GO:0071407=GO_REF:0000033, GO:0001957=GO_REF:0000033, GO:0045668=GO_REF:0000033, GO:0001934=PMID:20300119, GO:0016023=GO_REF:0000033, GO:0034613=PMID:17072303, GO:0019899=PMID:19759537, GO:0070016=GO_REF:0000033, GO:0005096=GO_REF:0000033} Q9Y2T1 Axin-2 protein 20130413 {GO:0008219=IEA, GO:0005881=IBA, GO:0008285=IMP, GO:0008013=NAS, GO:0005886=IBA, GO:0008283=IEA, GO:0003413=IEA, GO:0001756=IEA, GO:0030877=NAS, GO:0010718=IMP, GO:0038032=IEA, GO:0005634=IDA, GO:0030282=IEA, GO:0090244=IBA, GO:0035414=IMP, GO:0009950=IBA, GO:0005622=IEA, GO:2000054=IEA, GO:0005737=IDA, GO:0045860=IEA, GO:0042476=IMP, GO:0048255=IMP, GO:0004871=IEA, GO:0090090=IMP, GO:0010942=IMP, GO:0005938=IBA, GO:0031625=IPI, GO:0070602=IMP, GO:0005813=IDA, GO:0019901=IBA, GO:0061181=IEA, GO:0014069=IBA, GO:0070411=IEA, GO:0007275=IEA, GO:0032423=IMP, GO:0043570=IMP, GO:0043547=IBA, GO:0043234=IEA, GO:0071407=IBA, GO:0001957=IBA, GO:0045668=IBA, GO:0001934=IMP, GO:0016023=IBA, GO:0034613=IDA, GO:0019899=IPI, GO:0070016=IBA, GO:0005096=IBA} Wnt receptor signaling pathway involved in somitogenesis, bone mineralization, cell death, cell proliferation, cellular protein localization, cellular response to organic cyclic compound, chondrocyte differentiation involved in endochondral bone morphogenesis, dorsal/ventral axis specification, intramembranous ossification, mRNA stabilization, maintenance of DNA repeat elements, multicellular organismal development, negative regulation of Wnt receptor signaling pathway involved in dorsal/ventral axis specification, negative regulation of canonical Wnt receptor signaling pathway, negative regulation of catenin import into nucleus, negative regulation of cell proliferation, negative regulation of osteoblast differentiation, odontogenesis, positive regulation of GTPase activity, positive regulation of cell death, positive regulation of epithelial to mesenchymal transition, positive regulation of protein kinase activity, positive regulation of protein phosphorylation, regulation of centromeric sister chromatid cohesion, regulation of chondrocyte development, regulation of mismatch repair, somitogenesis, termination of G-protein coupled receptor signaling pathway beta-catenin destruction complex, cell cortex, centrosome, cytoplasm, cytoplasmic membrane-bounded vesicle, cytoplasmic microtubule, intracellular, nucleus, plasma membrane, postsynaptic density, protein complex GTPase activator activity, I-SMAD binding, armadillo repeat domain binding, beta-catenin binding, enzyme binding, protein kinase binding, signal transducer activity, ubiquitin protein ligase binding Human PANTHER:PTN000090250 AXL PINC UniProtKB {GO:0006909=PMID:21501828, GO:0005515=PMID:20088931, GO:0051897=GO_REF:0000019, GO:0060068=GO_REF:0000019, GO:0034101=GO_REF:0000019, GO:0042698=GO_REF:0000019, GO:0007283=GO_REF:0000019, GO:0005615=PMID:20088931, GO:0043524=GO_REF:0000019, GO:0006954=GO_REF:0000019, GO:0031668=GO_REF:0000019, GO:0034446=GO_REF:0000019, GO:0001779=GO_REF:0000019, GO:0009986=PMID:19657094, GO:0046982=GO_REF:0000019, GO:0030168=GO_REF:0000019, GO:0032720=GO_REF:0000019, GO:0043277=GO_REF:0000019, GO:2000669=PMID:19657094, GO:0005524=GO_REF:0000037, GO:0007165=PMID:1656220, GO:0071222=PMID:19657094, GO:0005887=PMID:1656220, GO:0001974=GO_REF:0000019, GO:0045087=GO_REF:0000037, GO:0001786=PMID:21501828, GO:0043491=GO_REF:0000019, GO:0051250=GO_REF:0000019, GO:0021885=GO_REF:0000019, GO:0004713=GO_REF:0000002, GO:0001764=GO_REF:0000019, GO:0004714=GO_REF:0000003, GO:0032940=GO_REF:0000019, GO:0007167=GO_REF:0000019} P30530 Tyrosine-protein kinase receptor UFO protein 20030904 {GO:0006909=IDA, GO:0005515=IPI, GO:0051897=IEA, GO:0060068=IEA, GO:0034101=IEA, GO:0042698=IEA, GO:0007283=IEA, GO:0005615=IDA, GO:0043524=IEA, GO:0006954=IEA, GO:0031668=IEA, GO:0034446=IEA, GO:0001779=IEA, GO:0009986=IDA, GO:0046982=IEA, GO:0030168=IEA, GO:0032720=IEA, GO:0043277=IEA, GO:2000669=IDA, GO:0005524=IEA, GO:0007165=TAS, GO:0071222=IDA, GO:0005887=TAS, GO:0001974=IEA, GO:0045087=IEA, GO:0001786=IDA, GO:0043491=IEA, GO:0051250=IEA, GO:0021885=IEA, GO:0004713=IEA, GO:0001764=IEA, GO:0004714=IEA, GO:0032940=IEA, GO:0007167=IEA} apoptotic cell clearance, blood vessel remodeling, cellular response to extracellular stimulus, cellular response to lipopolysaccharide, enzyme linked receptor protein signaling pathway, erythrocyte homeostasis, forebrain cell migration, inflammatory response, innate immune response, natural killer cell differentiation, negative regulation of dendritic cell apoptotic process, negative regulation of lymphocyte activation, negative regulation of neuron apoptotic process, negative regulation of tumor necrosis factor production, neuron migration, ovulation cycle, phagocytosis, platelet activation, positive regulation of protein kinase B signaling cascade, protein kinase B signaling cascade, secretion by cell, signal transduction, spermatogenesis, substrate adhesion-dependent cell spreading, vagina development cell surface, extracellular space, integral to plasma membrane ATP binding, phosphatidylserine binding, protein binding, protein heterodimerization activity, protein tyrosine kinase activity, transmembrane receptor protein tyrosine kinase activity Human AZGP1 UniProtKB UniProtKB {GO:0006955=GO_REF:0000002, GO:0008285=PMID:10462714, GO:0019882=GO_REF:0000002, GO:0042612=GO_REF:0000002, GO:0004540=PMID:10462714, GO:0005576=PMID:14718574, GO:0008320=PMID:6896906, GO:0007155=GO_REF:0000024} P25311 Zinc-alpha-2-glycoprotein protein 20040512 {GO:0006955=IEA, GO:0008285=NAS, GO:0019882=IEA, GO:0042612=IEA, GO:0004540=NAS, GO:0005576=NAS, GO:0008320=NAS, GO:0007155=ISS} antigen processing and presentation, cell adhesion, immune response, negative regulation of cell proliferation MHC class I protein complex, extracellular region protein transmembrane transporter activity, ribonuclease activity Human AZI1 HPA UniProtKB {GO:0003674=GO_REF:0000015, GO:0008150=GO_REF:0000015, GO:0005813=GO_REF:0000052, GO:0000086=Reactome:REACT_2203, GO:0015630=GO_REF:0000052, GO:0007275=GO_REF:0000037, GO:0007283=GO_REF:0000037, GO:0000278=Reactome:REACT_152, GO:0030154=GO_REF:0000037, GO:0043231=GO_REF:0000052, GO:0005829=Reactome:REACT_15470} Q9UPN4 5-azacytidine-induced protein 1 protein 20101115 {GO:0003674=ND, GO:0008150=ND, GO:0005813=IDA, GO:0000086=TAS, GO:0015630=IDA, GO:0007275=IEA, GO:0007283=IEA, GO:0000278=TAS, GO:0030154=IEA, GO:0043231=IDA, GO:0005829=TAS} G2/M transition of mitotic cell cycle, biological_process, cell differentiation, mitotic cell cycle, multicellular organismal development, spermatogenesis centrosome, cytosol, intracellular membrane-bounded organelle, microtubule cytoskeleton molecular_function Human AZI2 HPA UniProtKB {GO:0005739=GO_REF:0000052, GO:0005737=GO_REF:0000052, GO:0005886=GO_REF:0000052, GO:0007249=GO_REF:0000019} Q9H6S1 5-azacytidine-induced protein 2 protein 20101115 {GO:0005739=IDA, GO:0005737=IDA, GO:0005886=IDA, GO:0007249=IEA} I-kappaB kinase/NF-kappaB cascade cytoplasm, mitochondrion, plasma membrane Human AZIN1 GOC UniProtKB {GO:0004857=PMID:9349715, GO:0042978=GO_REF:0000019, GO:0034641=Reactome:REACT_13, GO:0006596=GO_REF:0000037, GO:0006521=Reactome:REACT_13565, GO:0044281=Reactome:REACT_111217, GO:0003824=GO_REF:0000002, GO:0043086=PMID:9349715, GO:0005829=Reactome:REACT_13578} O14977 Antizyme inhibitor 1 protein 20130413 {GO:0004857=TAS, GO:0042978=IEA, GO:0034641=TAS, GO:0006596=IEA, GO:0006521=TAS, GO:0044281=TAS, GO:0003824=IEA, GO:0043086=TAS, GO:0005829=TAS} cellular nitrogen compound metabolic process, negative regulation of catalytic activity, polyamine biosynthetic process, regulation of cellular amino acid metabolic process, small molecule metabolic process cytosol catalytic activity, enzyme inhibitor activity, ornithine decarboxylase activator activity Human AZU1 UniProtKB UniProtKB {GO:0043066=PMID:10510329, GO:0004252=GO_REF:0000002, GO:0008347=PMID:12465046, GO:0042535=PMID:12465046, GO:0042582=PMID:11861296, GO:0050725=PMID:12465046, GO:0005576=PMID:11861296, GO:0007205=PMID:12465046, GO:0045785=PMID:12826073, GO:0050930=PMID:12465046, GO:0045348=PMID:12465046, GO:0050829=PMID:12465046, GO:0050766=PMID:12465046, GO:0050754=PMID:12465046, GO:0006954=PMID:12678126, GO:0042117=PMID:12465046, GO:0015643=PMID:10534120, GO:0045123=PMID:11861296, GO:0006508=GO_REF:0000002, GO:0043114=PMID:11861296, GO:0048246=PMID:1919011, GO:0001774=PMID:12465046, GO:0008201=PMID:11994286} P20160 Azurocidin protein 20031111 {GO:0043066=NAS, GO:0004252=IEA, GO:0008347=IDA, GO:0042535=IDA, GO:0042582=IDA, GO:0050725=IDA, GO:0005576=NAS, GO:0007205=TAS, GO:0045785=IDA, GO:0050930=NAS, GO:0045348=IEP, GO:0050829=TAS, GO:0050766=IDA, GO:0050754=IDA, GO:0006954=NAS, GO:0042117=TAS, GO:0015643=NAS, GO:0045123=NAS, GO:0006508=IEA, GO:0043114=NAS, GO:0048246=NAS, GO:0001774=IEP, GO:0008201=NAS} cellular extravasation, defense response to Gram-negative bacterium, glial cell migration, induction of positive chemotaxis, inflammatory response, macrophage chemotaxis, microglial cell activation, monocyte activation, negative regulation of apoptotic process, positive regulation of MHC class II biosynthetic process, positive regulation of cell adhesion, positive regulation of fractalkine biosynthetic process, positive regulation of interleukin-1 beta biosynthetic process, positive regulation of phagocytosis, positive regulation of tumor necrosis factor biosynthetic process, protein kinase C-activating G-protein coupled receptor signaling pathway, proteolysis, regulation of vascular permeability azurophil granule, extracellular region heparin binding, serine-type endopeptidase activity, toxic substance binding Human B2M IntAct UniProtKB {GO:0005515=PMID:15723809, GO:0002474=Reactome:REACT_75820, GO:0005886=Reactome:REACT_147879, GO:0019221=Reactome:REACT_25229, GO:0002237=GO_REF:0000019, GO:0005615=GO_REF:0000019, GO:0042026=GO_REF:0000019, GO:0005737=GO_REF:0000052, GO:0006955=GO_REF:0000002, GO:0030670=Reactome:REACT_111215, GO:0016032=Reactome:REACT_6185, GO:0060333=Reactome:REACT_25078, GO:0012507=Reactome:REACT_75894, GO:0033077=GO_REF:0000019, GO:0002480=Reactome:REACT_111168, GO:0002481=GO_REF:0000019, GO:0005794=GO_REF:0000052, GO:0042612=GO_REF:0000037, GO:0042493=GO_REF:0000019, GO:0042590=Reactome:REACT_111119, GO:0005576=Reactome:REACT_75876, GO:0050690=Reactome:REACT_11149, GO:0031905=Reactome:REACT_111222, GO:0000139=Reactome:REACT_75894, GO:0001916=GO_REF:0000019, GO:0031901=Reactome:REACT_11229, GO:0045087=Reactome:REACT_6802, GO:0050776=Reactome:REACT_11152, GO:0002479=Reactome:REACT_111178, GO:0005788=Reactome:REACT_75922, GO:0009897=GO_REF:0000019, GO:0046686=GO_REF:0000019} P61769 Beta-2-microglobulin protein 20130415 {GO:0005515=IPI, GO:0002474=TAS, GO:0005886=TAS, GO:0019221=TAS, GO:0002237=IEA, GO:0005615=IEA, GO:0042026=IEA, GO:0005737=IDA, GO:0006955=IEA, GO:0030670=TAS, GO:0016032=TAS, GO:0060333=TAS, GO:0012507=TAS, GO:0033077=IEA, GO:0002480=TAS, GO:0002481=IEA, GO:0005794=IDA, GO:0042612=IEA, GO:0042493=IEA, GO:0042590=TAS, GO:0005576=TAS, GO:0050690=TAS, GO:0031905=TAS, GO:0000139=TAS, GO:0001916=IEA, GO:0031901=TAS, GO:0045087=TAS, GO:0050776=TAS, GO:0002479=TAS, GO:0005788=TAS, GO:0009897=IEA, GO:0046686=IEA} T cell differentiation in thymus, antigen processing and presentation of exogenous peptide antigen via MHC class I, antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent, antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent, antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent, antigen processing and presentation of peptide antigen via MHC class I, cytokine-mediated signaling pathway, immune response, innate immune response, interferon-gamma-mediated signaling pathway, positive regulation of T cell mediated cytotoxicity, protein refolding, regulation of defense response to virus by virus, regulation of immune response, response to cadmium ion, response to drug, response to molecule of bacterial origin, viral reproduction ER to Golgi transport vesicle membrane, Golgi apparatus, Golgi membrane, MHC class I protein complex, cytoplasm, early endosome lumen, early endosome membrane, endoplasmic reticulum lumen, external side of plasma membrane, extracellular region, extracellular space, phagocytic vesicle membrane, plasma membrane protein binding Human UniProtKB:P06126 B3GALNT1 UniPathway UniProtKB {GO:0009312=GO_REF:0000019, GO:0000139=GO_REF:0000039, GO:0016020=GO_REF:0000002, GO:0008499=GO_REF:0000019, GO:0006486=GO_REF:0000041, GO:0016021=GO_REF:0000037, GO:0047273=GO_REF:0000003, GO:0008378=GO_REF:0000002} O75752 UDP-GalNAc:beta-1,3-N-acetylgalactosaminyltransferase 1 protein 20130413 {GO:0009312=IEA, GO:0000139=IEA, GO:0016020=IEA, GO:0008499=IEA, GO:0006486=IEA, GO:0016021=IEA, GO:0047273=IEA, GO:0008378=IEA} oligosaccharide biosynthetic process, protein glycosylation Golgi membrane, integral to membrane, membrane UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity, galactosylgalactosylglucosylceramide beta-D-acetylgalactosaminyltransferase activity, galactosyltransferase activity Human UniPathway:UPA00378 B3GALNT2 UniPathway UniProtKB {GO:0000139=GO_REF:0000039, GO:0006486=GO_REF:0000041, GO:0016021=GO_REF:0000037, GO:0008378=GO_REF:0000002} Q8NCR0 UDP-GalNAc:beta-1,3-N-acetylgalactosaminyltransferase 2 protein 20130413 {GO:0000139=IEA, GO:0006486=IEA, GO:0016021=IEA, GO:0008378=IEA} protein glycosylation Golgi membrane, integral to membrane galactosyltransferase activity Human UniPathway:UPA00378 B3GALT1 UniProtKB UniProtKB {GO:0009312=GO_REF:0000019, GO:0000139=GO_REF:0000039, GO:0008499=PMID:9582303, GO:0006486=GO_REF:0000041, GO:0016021=PMID:9582303, GO:0030259=GO_REF:0000029} Q9Y5Z6 Beta-1,3-galactosyltransferase 1 protein 20021106 {GO:0009312=IEA, GO:0000139=IEA, GO:0008499=IDA, GO:0006486=IEA, GO:0016021=NAS, GO:0030259=NAS} lipid glycosylation, oligosaccharide biosynthetic process, protein glycosylation Golgi membrane, integral to membrane UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity Human B3GALT2 UniPathway UniProtKB {GO:0009312=GO_REF:0000019, GO:0000139=GO_REF:0000039, GO:0008499=GO_REF:0000019, GO:0006486=GO_REF:0000041, GO:0016021=GO_REF:0000037} O43825 Beta-1,3-galactosyltransferase 2 protein 20130413 {GO:0009312=IEA, GO:0000139=IEA, GO:0008499=IEA, GO:0006486=IEA, GO:0016021=IEA} oligosaccharide biosynthetic process, protein glycosylation Golgi membrane, integral to membrane UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity Human UniPathway:UPA00378 B3GALT4 PINC UniProtKB {GO:0000139=GO_REF:0000039, GO:0008499=PMID:9582303, GO:0047915=GO_REF:0000003, GO:0006486=GO_REF:0000041, GO:0016021=GO_REF:0000037} O96024 Beta-1,3-galactosyltransferase 4 protein 20030904 {GO:0000139=IEA, GO:0008499=TAS, GO:0047915=IEA, GO:0006486=IEA, GO:0016021=IEA} protein glycosylation Golgi membrane, integral to membrane UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity, ganglioside galactosyltransferase activity Human B3GALT6 Reactome UniProtKB {GO:0008499=GO_REF:0000019, GO:0005975=Reactome:REACT_474, GO:0005797=PMID:11551958, GO:0044281=Reactome:REACT_111217, GO:0015012=GO_REF:0000041, GO:0006024=PMID:11551958, GO:0030206=GO_REF:0000041, GO:0035250=PMID:11551958, GO:0000139=Reactome:REACT_121213, GO:0032580=GO_REF:0000039, GO:0006486=GO_REF:0000002, GO:0016021=GO_REF:0000037, GO:0030204=Reactome:REACT_121206, GO:0030203=Reactome:REACT_121408, GO:0047220=GO_REF:0000003} Q96L58 Beta-1,3-galactosyltransferase 6 protein 20130301 {GO:0008499=IEA, GO:0005975=TAS, GO:0005797=IDA, GO:0044281=TAS, GO:0015012=IEA, GO:0006024=IMP, GO:0030206=IEA, GO:0035250=IDA, GO:0000139=TAS, GO:0032580=IEA, GO:0006486=IEA, GO:0016021=IEA, GO:0030204=TAS, GO:0030203=TAS, GO:0047220=IEA} carbohydrate metabolic process, chondroitin sulfate biosynthetic process, chondroitin sulfate metabolic process, glycosaminoglycan biosynthetic process, glycosaminoglycan metabolic process, heparan sulfate proteoglycan biosynthetic process, protein glycosylation, small molecule metabolic process Golgi cisterna membrane, Golgi medial cisterna, Golgi membrane, integral to membrane UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity, UDP-galactosyltransferase activity, galactosylxylosylprotein 3-beta-galactosyltransferase activity Human B3GALTL UniPathway UniProtKB {GO:0016757=GO_REF:0000037, GO:0005789=GO_REF:0000039, GO:0006486=GO_REF:0000041, GO:0016021=GO_REF:0000037, GO:0006004=GO_REF:0000037} Q6Y288 Beta-1,3-glucosyltransferase protein 20130413 {GO:0016757=IEA, GO:0005789=IEA, GO:0006486=IEA, GO:0016021=IEA, GO:0006004=IEA} fucose metabolic process, protein glycosylation endoplasmic reticulum membrane, integral to membrane transferase activity, transferring glycosyl groups Human UniPathway:UPA00378 B3GAT1 Reactome UniProtKB {GO:0015018=GO_REF:0000003, GO:0000139=Reactome:REACT_120897, GO:0016020=GO_REF:0000002, GO:0005975=Reactome:REACT_474, GO:0008499=GO_REF:0000019, GO:0006486=GO_REF:0000041, GO:0044281=Reactome:REACT_111217, GO:0016021=GO_REF:0000037, GO:0030204=Reactome:REACT_121206, GO:0030203=Reactome:REACT_121408, GO:0046872=GO_REF:0000037} Q9P2W7 Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 1 protein 20111101 {GO:0015018=IEA, GO:0000139=TAS, GO:0016020=IEA, GO:0005975=TAS, GO:0008499=IEA, GO:0006486=IEA, GO:0044281=TAS, GO:0016021=IEA, GO:0030204=TAS, GO:0030203=TAS, GO:0046872=IEA} carbohydrate metabolic process, chondroitin sulfate metabolic process, glycosaminoglycan metabolic process, protein glycosylation, small molecule metabolic process Golgi membrane, integral to membrane, membrane UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity, galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity, metal ion binding Human B3GAT3 Reactome UniProtKB {GO:0005801=PMID:21763480, GO:0050650=PMID:21763480, GO:0030145=GO_REF:0000029, GO:0005794=PMID:21763480, GO:0050651=PMID:21763480, GO:0005975=Reactome:REACT_474, GO:0015020=PMID:21763480, GO:0044281=Reactome:REACT_111217, GO:0015012=PMID:21763480, GO:0006024=PMID:10842173, GO:0015018=PMID:10842173, GO:0016020=GO_REF:0000002, GO:0000139=Reactome:REACT_120897, GO:0006486=GO_REF:0000041, GO:0016021=PMID:10842173, GO:0030204=Reactome:REACT_121206, GO:0030203=Reactome:REACT_121408} O94766 Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 3 protein 20111101 {GO:0005801=IDA, GO:0050650=IDA, GO:0030145=NAS, GO:0005794=IDA, GO:0050651=IDA, GO:0005975=TAS, GO:0015020=IMP, GO:0044281=TAS, GO:0015012=IDA, GO:0006024=NAS, GO:0015018=NAS, GO:0016020=IEA, GO:0000139=TAS, GO:0006486=IEA, GO:0016021=NAS, GO:0030204=TAS, GO:0030203=TAS} carbohydrate metabolic process, chondroitin sulfate metabolic process, chondroitin sulfate proteoglycan biosynthetic process, dermatan sulfate proteoglycan biosynthetic process, glycosaminoglycan biosynthetic process, glycosaminoglycan metabolic process, heparan sulfate proteoglycan biosynthetic process, protein glycosylation, small molecule metabolic process Golgi apparatus, Golgi membrane, cis-Golgi network, integral to membrane, membrane galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity, glucuronosyltransferase activity, manganese ion binding Human B3GNT1 Reactome UniProtKB {GO:0030173=PMID:9405606, GO:0008532=PMID:9405606, GO:0018146=Reactome:REACT_121120, GO:0000139=Reactome:REACT_121143, GO:0005975=Reactome:REACT_474, GO:0030311=PMID:9405606, GO:0006486=GO_REF:0000041, GO:0044281=Reactome:REACT_111217, GO:0030203=Reactome:REACT_121315, GO:0042339=Reactome:REACT_121288} O43505 N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase protein 20130301 {GO:0030173=NAS, GO:0008532=IDA, GO:0018146=TAS, GO:0000139=TAS, GO:0005975=TAS, GO:0030311=IDA, GO:0006486=IEA, GO:0044281=TAS, GO:0030203=TAS, GO:0042339=TAS} carbohydrate metabolic process, glycosaminoglycan metabolic process, keratan sulfate biosynthetic process, keratan sulfate metabolic process, poly-N-acetyllactosamine biosynthetic process, protein glycosylation, small molecule metabolic process Golgi membrane, integral to Golgi membrane N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity Human B3GNT2 Reactome UniProtKB {GO:0007608=GO_REF:0000019, GO:0008499=GO_REF:0000029, GO:0005975=Reactome:REACT_474, GO:0016266=Reactome:REACT_115606, GO:0044281=Reactome:REACT_111217, GO:0042339=Reactome:REACT_121288, GO:0008150=GO_REF:0000015, GO:0000139=Reactome:REACT_121143, GO:0018146=Reactome:REACT_121120, GO:0007411=GO_REF:0000019, GO:0016021=GO_REF:0000029, GO:0030203=Reactome:REACT_121315, GO:0044267=Reactome:REACT_17015, GO:0043687=Reactome:REACT_22161} Q9NY97 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2 protein 20130301 {GO:0007608=IEA, GO:0008499=NAS, GO:0005975=TAS, GO:0016266=TAS, GO:0044281=TAS, GO:0042339=TAS, GO:0008150=ND, GO:0000139=TAS, GO:0018146=TAS, GO:0007411=IEA, GO:0016021=NAS, GO:0030203=TAS, GO:0044267=TAS, GO:0043687=TAS} O-glycan processing, axon guidance, biological_process, carbohydrate metabolic process, cellular protein metabolic process, glycosaminoglycan metabolic process, keratan sulfate biosynthetic process, keratan sulfate metabolic process, post-translational protein modification, sensory perception of smell, small molecule metabolic process Golgi membrane, integral to membrane UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity Human B3GNT4 Reactome UniProtKB {GO:0018146=Reactome:REACT_121120, GO:0000139=Reactome:REACT_121143, GO:0005975=Reactome:REACT_474, GO:0016266=Reactome:REACT_115606, GO:0044281=Reactome:REACT_111217, GO:0016021=GO_REF:0000037, GO:0044267=Reactome:REACT_17015, GO:0030203=Reactome:REACT_121315, GO:0008378=GO_REF:0000002, GO:0043687=Reactome:REACT_22161, GO:0042339=Reactome:REACT_121288} Q9C0J1 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4 protein 20130301 {GO:0018146=TAS, GO:0000139=TAS, GO:0005975=TAS, GO:0016266=TAS, GO:0044281=TAS, GO:0016021=IEA, GO:0044267=TAS, GO:0030203=TAS, GO:0008378=IEA, GO:0043687=TAS, GO:0042339=TAS} O-glycan processing, carbohydrate metabolic process, cellular protein metabolic process, glycosaminoglycan metabolic process, keratan sulfate biosynthetic process, keratan sulfate metabolic process, post-translational protein modification, small molecule metabolic process Golgi membrane, integral to membrane galactosyltransferase activity Human B3GNT5 Reactome UniProtKB {GO:0009247=PMID:11384981, GO:0047256=GO_REF:0000003, GO:0016266=Reactome:REACT_115606, GO:0008457=PMID:11384981, GO:0007417=PMID:11384981, GO:0008378=GO_REF:0000002, GO:0005622=PMID:11384981, GO:0016020=GO_REF:0000002, GO:0000139=Reactome:REACT_116000, GO:0006486=PMID:11384981, GO:0016021=GO_REF:0000037, GO:0008917=GO_REF:0000019, GO:0044267=Reactome:REACT_17015, GO:0043687=Reactome:REACT_22161} Q9BYG0 Lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase protein 20130301 {GO:0009247=TAS, GO:0047256=IEA, GO:0016266=TAS, GO:0008457=IDA, GO:0007417=IDA, GO:0008378=IEA, GO:0005622=IDA, GO:0016020=IEA, GO:0000139=TAS, GO:0006486=TAS, GO:0016021=IEA, GO:0008917=IEA, GO:0044267=TAS, GO:0043687=TAS} O-glycan processing, cellular protein metabolic process, central nervous system development, glycolipid biosynthetic process, post-translational protein modification, protein glycosylation Golgi membrane, integral to membrane, intracellular, membrane beta-galactosyl-N-acetylglucosaminylgalactosylglucosyl-ceramide beta-1,3-acetylglucosaminyltransferase activity, galactosyltransferase activity, lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase activity, lipopolysaccharide N-acetylglucosaminyltransferase activity Human B3GNT9 UniProtKB UniProtKB {GO:0000139=GO_REF:0000039, GO:0006486=GO_REF:0000002, GO:0016021=GO_REF:0000037, GO:0008378=GO_REF:0000002} Q6UX72 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 9 protein 20130413 {GO:0000139=IEA, GO:0006486=IEA, GO:0016021=IEA, GO:0008378=IEA} protein glycosylation Golgi membrane, integral to membrane galactosyltransferase activity Human UniProtKB-SubCell:SL-0134 B3GNTL1 UniProtKB UniProtKB {GO:0016757=GO_REF:0000037} Q67FW5 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase-like protein 1 protein 20130413 {GO:0016757=IEA} transferase activity, transferring glycosyl groups Human UniProtKB-KW:KW-0328 B4GALNT1 PINC UniProtKB {GO:0005886=GO_REF:0000019, GO:0006687=PMID:1601877, GO:0016757=GO_REF:0000038, GO:0019915=GO_REF:0000019, GO:0005975=PMID:1601877, GO:0007283=GO_REF:0000019, GO:0008376=GO_REF:0000019, GO:0030173=GO_REF:0000002, GO:0016020=PMID:1601877, GO:0003947=GO_REF:0000003, GO:0001574=GO_REF:0000019, GO:0006486=GO_REF:0000041, GO:0030259=GO_REF:0000002} Q00973 Beta-1,4 N-acetylgalactosaminyltransferase 1 protein 20030904 {GO:0005886=IEA, GO:0006687=TAS, GO:0016757=IEA, GO:0019915=IEA, GO:0005975=TAS, GO:0007283=IEA, GO:0008376=IEA, GO:0030173=IEA, GO:0016020=TAS, GO:0003947=IEA, GO:0001574=IEA, GO:0006486=IEA, GO:0030259=IEA} carbohydrate metabolic process, ganglioside biosynthetic process, glycosphingolipid metabolic process, lipid glycosylation, lipid storage, protein glycosylation, spermatogenesis integral to Golgi membrane, membrane, plasma membrane (N-acetylneuraminyl)-galactosylglucosylceramide N-acetylgalactosaminyltransferase activity, acetylgalactosaminyltransferase activity, transferase activity, transferring glycosyl groups Human B4GALT1 HPA UniProtKB {GO:0008092=GO_REF:0000019, GO:0030057=PMID:3917437, GO:0060046=GO_REF:0000019, GO:0030112=PMID:3917437, GO:0030879=GO_REF:0000019, GO:0031526=PMID:3917437, GO:0050900=GO_REF:0000019, GO:0009101=GO_REF:0000019, GO:0003945=PMID:2120039, GO:0007219=Reactome:REACT_299, GO:0030198=GO_REF:0000019, GO:0002064=GO_REF:0000019, GO:0030203=Reactome:REACT_121315, GO:0018279=Reactome:REACT_22426, GO:0002526=GO_REF:0000019, GO:0005794=GO_REF:0000052, GO:0009986=GO_REF:0000019, GO:0016757=GO_REF:0000002, GO:0005975=GO_REF:0000002, GO:0004461=PMID:33805, GO:0008378=PMID:7540104, GO:0044267=Reactome:REACT_17015, GO:0009897=PMID:3917437, GO:0043687=Reactome:REACT_22161, GO:0005989=GO_REF:0000019, GO:0008285=GO_REF:0000019, GO:0005886=GO_REF:0000019, GO:0044281=Reactome:REACT_111217, GO:0046872=GO_REF:0000037, GO:0016323=PMID:3917437, GO:0032580=GO_REF:0000039, GO:0007155=GO_REF:0000019, GO:0060054=GO_REF:0000019, GO:0009312=PMID:2120039, GO:0060058=GO_REF:0000019, GO:0060055=GO_REF:0000019, GO:0005576=GO_REF:0000039, GO:0003831=PMID:33805, GO:0045136=GO_REF:0000019, GO:0007339=GO_REF:0000019, GO:0042339=Reactome:REACT_121288, GO:0035250=PMID:3917437, GO:0000139=Reactome:REACT_120962, GO:0018146=Reactome:REACT_121120, GO:0000138=PMID:6121819, GO:0007341=GO_REF:0000019, GO:0016021=GO_REF:0000037, GO:0048754=GO_REF:0000019, GO:0006012=GO_REF:0000019, GO:0051270=GO_REF:0000019} Q86XA6 Lactose synthase A protein protein 20080205 {GO:0008092=IEA, GO:0030057=IDA, GO:0060046=IEA, GO:0030112=IDA, GO:0030879=IEA, GO:0031526=IDA, GO:0050900=IEA, GO:0009101=IEA, GO:0003945=IDA, GO:0007219=TAS, GO:0030198=IEA, GO:0002064=IEA, GO:0030203=TAS, GO:0018279=TAS, GO:0002526=IEA, GO:0005794=IDA, GO:0009986=IEA, GO:0016757=IEA, GO:0005975=IEA, GO:0004461=IDA, GO:0008378=NAS, GO:0044267=TAS, GO:0009897=IDA, GO:0043687=TAS, GO:0005989=IEA, GO:0008285=IEA, GO:0005886=IEA, GO:0044281=TAS, GO:0046872=IEA, GO:0016323=IDA, GO:0032580=IEA, GO:0007155=IEA, GO:0060054=IEA, GO:0009312=IDA, GO:0060058=IEA, GO:0060055=IEA, GO:0005576=IEA, GO:0003831=IDA, GO:0045136=IEA, GO:0007339=IEA, GO:0042339=TAS, GO:0035250=IDA, GO:0000139=TAS, GO:0018146=TAS, GO:0000138=IDA, GO:0007341=IEA, GO:0016021=IEA, GO:0048754=IEA, GO:0006012=IEA, GO:0051270=IEA} Notch signaling pathway, acute inflammatory response, angiogenesis involved in wound healing, binding of sperm to zona pellucida, branching morphogenesis of an epithelial tube, carbohydrate metabolic process, cell adhesion, cellular protein metabolic process, development of secondary sexual characteristics, epithelial cell development, extracellular matrix organization, galactose metabolic process, glycoprotein biosynthetic process, glycosaminoglycan metabolic process, keratan sulfate biosynthetic process, keratan sulfate metabolic process, lactose biosynthetic process, leukocyte migration, mammary gland development, negative regulation of cell proliferation, oligosaccharide biosynthetic process, penetration of zona pellucida, positive regulation of apoptotic process involved in mammary gland involution, positive regulation of epithelial cell proliferation involved in wound healing, post-translational protein modification, protein N-linked glycosylation via asparagine, regulation of acrosome reaction, regulation of cellular component movement, small molecule metabolic process Golgi apparatus, Golgi cisterna membrane, Golgi membrane, Golgi trans cisterna, basolateral plasma membrane, brush border membrane, cell surface, desmosome, external side of plasma membrane, extracellular region, glycocalyx, integral to membrane, plasma membrane N-acetyllactosamine synthase activity, UDP-galactosyltransferase activity, beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity, cytoskeletal protein binding, galactosyltransferase activity, lactose synthase activity, metal ion binding, transferase activity, transferring glycosyl groups Human B4GALT2 Reactome UniProtKB {GO:0005975=Reactome:REACT_474, GO:0004461=GO_REF:0000003, GO:0003831=GO_REF:0000003, GO:0044281=Reactome:REACT_111217, GO:0008378=PMID:9405390, GO:0046872=GO_REF:0000037, GO:0042339=Reactome:REACT_121288, GO:0003945=GO_REF:0000003, GO:0000139=Reactome:REACT_120962, GO:0018146=Reactome:REACT_121120, GO:0032580=GO_REF:0000039, GO:0016021=GO_REF:0000037, GO:0044267=Reactome:REACT_17015, GO:0030203=Reactome:REACT_121315, GO:0043687=Reactome:REACT_22161, GO:0018279=Reactome:REACT_22426} O60909 Beta-1,4-galactosyltransferase 2 protein 20101008 {GO:0005975=TAS, GO:0004461=IEA, GO:0003831=IEA, GO:0044281=TAS, GO:0008378=TAS, GO:0046872=IEA, GO:0042339=TAS, GO:0003945=IEA, GO:0000139=TAS, GO:0018146=TAS, GO:0032580=IEA, GO:0016021=IEA, GO:0044267=TAS, GO:0030203=TAS, GO:0043687=TAS, GO:0018279=TAS} carbohydrate metabolic process, cellular protein metabolic process, glycosaminoglycan metabolic process, keratan sulfate biosynthetic process, keratan sulfate metabolic process, post-translational protein modification, protein N-linked glycosylation via asparagine, small molecule metabolic process Golgi cisterna membrane, Golgi membrane, integral to membrane N-acetyllactosamine synthase activity, beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity, galactosyltransferase activity, lactose synthase activity, metal ion binding Human B4GALT3 HPA UniProtKB {GO:0005794=GO_REF:0000052, GO:0005975=Reactome:REACT_474, GO:0003831=GO_REF:0000003, GO:0044281=Reactome:REACT_111217, GO:0008378=PMID:9405390, GO:0046872=GO_REF:0000037, GO:0042339=Reactome:REACT_121288, GO:0005737=GO_REF:0000052, GO:0003945=GO_REF:0000003, GO:0000139=Reactome:REACT_120962, GO:0018146=Reactome:REACT_121120, GO:0032580=GO_REF:0000039, GO:0016021=GO_REF:0000037, GO:0044267=Reactome:REACT_17015, GO:0030203=Reactome:REACT_121315, GO:0018279=Reactome:REACT_22426, GO:0043687=Reactome:REACT_22161} O60512 Beta-1,4-galactosyltransferase 3 protein 20080205 {GO:0005794=IDA, GO:0005975=TAS, GO:0003831=IEA, GO:0044281=TAS, GO:0008378=TAS, GO:0046872=IEA, GO:0042339=TAS, GO:0005737=IDA, GO:0003945=IEA, GO:0000139=TAS, GO:0018146=TAS, GO:0032580=IEA, GO:0016021=IEA, GO:0044267=TAS, GO:0030203=TAS, GO:0018279=TAS, GO:0043687=TAS} carbohydrate metabolic process, cellular protein metabolic process, glycosaminoglycan metabolic process, keratan sulfate biosynthetic process, keratan sulfate metabolic process, post-translational protein modification, protein N-linked glycosylation via asparagine, small molecule metabolic process Golgi apparatus, Golgi cisterna membrane, Golgi membrane, cytoplasm, integral to membrane N-acetyllactosamine synthase activity, beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity, galactosyltransferase activity, metal ion binding Human B4GALT5 Reactome UniProtKB {GO:0005975=Reactome:REACT_474, GO:0016266=Reactome:REACT_115606, GO:0044281=Reactome:REACT_111217, GO:0008378=PMID:9597550, GO:0046872=GO_REF:0000037, GO:0042339=Reactome:REACT_121288, GO:0000139=Reactome:REACT_120962, GO:0018146=Reactome:REACT_121120, GO:0032580=GO_REF:0000039, GO:0016021=GO_REF:0000037, GO:0030203=Reactome:REACT_121315, GO:0044267=Reactome:REACT_17015, GO:0018279=Reactome:REACT_22426, GO:0043687=Reactome:REACT_22161} O43286 Beta-1,4-galactosyltransferase 5 protein 20101115 {GO:0005975=TAS, GO:0016266=TAS, GO:0044281=TAS, GO:0008378=TAS, GO:0046872=IEA, GO:0042339=TAS, GO:0000139=TAS, GO:0018146=TAS, GO:0032580=IEA, GO:0016021=IEA, GO:0030203=TAS, GO:0044267=TAS, GO:0018279=TAS, GO:0043687=TAS} O-glycan processing, carbohydrate metabolic process, cellular protein metabolic process, glycosaminoglycan metabolic process, keratan sulfate biosynthetic process, keratan sulfate metabolic process, post-translational protein modification, protein N-linked glycosylation via asparagine, small molecule metabolic process Golgi cisterna membrane, Golgi membrane, integral to membrane galactosyltransferase activity, metal ion binding Human B9D1 UniProtKB UniProtKB {GO:0042384=GO_REF:0000024, GO:0005813=PMID:19208769, GO:0035869=GO_REF:0000024, GO:0060271=GO_REF:0000024, GO:0036038=GO_REF:0000024, GO:0008158=GO_REF:0000024, GO:0005932=PMID:19208769, GO:0035085=GO_REF:0000039, GO:0007224=GO_REF:0000024} Q9UPM9 B9 domain-containing protein 1 protein 20110125 {GO:0042384=ISS, GO:0005813=IDA, GO:0035869=ISS, GO:0060271=ISS, GO:0036038=ISS, GO:0008158=ISS, GO:0005932=IDA, GO:0035085=IEA, GO:0007224=ISS} cilium assembly, cilium morphogenesis, smoothened signaling pathway TCTN-B9D complex, centrosome, ciliary transition zone, cilium axoneme, microtubule basal body hedgehog receptor activity Human UniProtKB:Q9NXB0 B9D2 Reactome UniProtKB {GO:0000236=Reactome:REACT_682, GO:0042384=GO_REF:0000024, GO:0005813=PMID:19208769, GO:0043015=GO_REF:0000024, GO:0000087=Reactome:REACT_910, GO:0036038=GO_REF:0000024, GO:0005634=GO_REF:0000039, GO:0005932=PMID:19208769, GO:0000278=Reactome:REACT_152, GO:0035085=GO_REF:0000039, GO:0000090=Reactome:REACT_1275, GO:0005829=Reactome:REACT_150414} Q9BPU9 B9 domain-containing protein 2 protein 20130213 {GO:0000236=TAS, GO:0042384=ISS, GO:0005813=IDA, GO:0043015=ISS, GO:0000087=TAS, GO:0036038=ISS, GO:0005634=IEA, GO:0005932=IDA, GO:0000278=TAS, GO:0035085=IEA, GO:0000090=TAS, GO:0005829=TAS} M phase of mitotic cell cycle, cilium assembly, mitotic anaphase, mitotic cell cycle, mitotic prometaphase TCTN-B9D complex, centrosome, cilium axoneme, cytosol, microtubule basal body, nucleus gamma-tubulin binding Human BAALC HPA UniProtKB {GO:0005813=GO_REF:0000052, GO:0005737=GO_REF:0000052, GO:0016020=GO_REF:0000039, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052} Q8WXS3 Brain and acute leukemia cytoplasmic protein protein 20101115 {GO:0005813=IDA, GO:0005737=IDA, GO:0016020=IEA, GO:0005730=IDA, GO:0005634=IDA} centrosome, cytoplasm, membrane, nucleolus, nucleus Human BAAT Reactome UniProtKB {GO:0004091=GO_REF:0000037, GO:0052815=PMID:12810727, GO:0006637=PMID:12810727, GO:0052817=PMID:12810727, GO:0016410=PMID:12239217, GO:0052816=PMID:12810727, GO:0005782=Reactome:REACT_9974, GO:0006699=Reactome:REACT_11054, GO:0019530=PMID:8034703, GO:0016290=GO_REF:0000003, GO:0002152=PMID:8034703, GO:0031100=GO_REF:0000019, GO:0005102=PMID:20178365, GO:0044281=Reactome:REACT_111217, GO:0005829=Reactome:REACT_9991, GO:0001889=GO_REF:0000019, GO:0015721=Reactome:REACT_11042, GO:0006631=GO_REF:0000037, GO:0006544=PMID:8034703, GO:0008206=Reactome:REACT_11040, GO:0047963=PMID:8034703} Q14032 Bile acid-CoA:amino acid N-acyltransferase protein 20130301 {GO:0004091=IEA, GO:0052815=IDA, GO:0006637=IDA, GO:0052817=IDA, GO:0016410=IDA, GO:0052816=IDA, GO:0005782=TAS, GO:0006699=TAS, GO:0019530=IDA, GO:0016290=IEA, GO:0002152=IDA, GO:0031100=IEA, GO:0005102=IPI, GO:0044281=TAS, GO:0005829=TAS, GO:0001889=IEA, GO:0015721=TAS, GO:0006631=IEA, GO:0006544=IDA, GO:0008206=TAS, GO:0047963=IDA} acyl-CoA metabolic process, bile acid and bile salt transport, bile acid biosynthetic process, bile acid conjugation, bile acid metabolic process, fatty acid metabolic process, glycine metabolic process, liver development, organ regeneration, small molecule metabolic process, taurine metabolic process cytosol, peroxisomal matrix N-acyltransferase activity, carboxylesterase activity, glycine N-choloyltransferase activity, long-chain acyl-CoA hydrolase activity, medium-chain acyl-CoA hydrolase activity, palmitoyl-CoA hydrolase activity, receptor binding, very long chain acyl-CoA hydrolase activity Human BABAM1 IntAct UniProtKB {GO:0005515=PMID:22153077, GO:0070531=PMID:19261748, GO:0005737=PMID:19261749, GO:0070552=PMID:19214193, GO:0070536=PMID:19261746, GO:0010212=PMID:19261748, GO:0031572=PMID:19261748, GO:0005634=PMID:19261748, GO:0045739=PMID:19261748, GO:0006302=PMID:19261748, GO:0016568=GO_REF:0000037} Q9NWV8 BRISC and BRCA1-A complex member 1 protein 20130415 {GO:0005515=IPI, GO:0070531=IDA, GO:0005737=IDA, GO:0070552=IDA, GO:0070536=IMP, GO:0010212=IMP, GO:0031572=IMP, GO:0005634=IDA, GO:0045739=IMP, GO:0006302=IMP, GO:0016568=IEA} G2 DNA damage checkpoint, chromatin modification, double-strand break repair, positive regulation of DNA repair, protein K63-linked deubiquitination, response to ionizing radiation BRCA1-A complex, BRISC complex, cytoplasm, nucleus protein binding Human UniProtKB:Q9H2K2 BACE1 PINC UniProtKB {GO:0008798=PMID:10591214, GO:0005802=PMID:11466313, GO:0030424=GO_REF:0000019, GO:0005794=PMID:12586838, GO:0009986=GO_REF:0000039, GO:0005783=GO_REF:0000039, GO:0050435=PMID:15080893, GO:0005887=PMID:12586838, GO:0006508=PMID:10531052, GO:0004190=PMID:10531052, GO:0006509=PMID:12354787, GO:0016021=PMID:10531052, GO:0019899=PMID:12586838, GO:0030659=GO_REF:0000039, GO:0005768=PMID:10531052} P56817 Beta-secretase 1 protein 20030904 {GO:0008798=TAS, GO:0005802=IDA, GO:0030424=IEA, GO:0005794=IDA, GO:0009986=IEA, GO:0005783=IEA, GO:0050435=IDA, GO:0005887=IDA, GO:0006508=IDA, GO:0004190=IDA, GO:0006509=TAS, GO:0016021=NAS, GO:0019899=IPI, GO:0030659=IEA, GO:0005768=IDA} beta-amyloid metabolic process, membrane protein ectodomain proteolysis, proteolysis Golgi apparatus, axon, cell surface, cytoplasmic vesicle membrane, endoplasmic reticulum, endosome, integral to membrane, integral to plasma membrane, trans-Golgi network aspartic-type endopeptidase activity, beta-aspartyl-peptidase activity, enzyme binding Human BACE2 UniProtKB UniProtKB {GO:0005794=PMID:11423558, GO:0016486=PMID:10749877, GO:0009986=GO_REF:0000039, GO:0005783=GO_REF:0000039, GO:0006508=PMID:10749877, GO:0006509=PMID:10591213, GO:0004190=PMID:10591213, GO:0016021=PMID:10749877, GO:0042985=PMID:12801932, GO:0005768=GO_REF:0000039} Q9Y5Z0 Beta-secretase 2 protein 20040526 {GO:0005794=IDA, GO:0016486=NAS, GO:0009986=IEA, GO:0005783=IEA, GO:0006508=NAS, GO:0006509=IDA, GO:0004190=IDA, GO:0016021=NAS, GO:0042985=IMP, GO:0005768=IEA} membrane protein ectodomain proteolysis, negative regulation of amyloid precursor protein biosynthetic process, peptide hormone processing, proteolysis Golgi apparatus, cell surface, endoplasmic reticulum, endosome, integral to membrane aspartic-type endopeptidase activity Human BACH1 UniProtKB UniProtKB {GO:0000117=PMID:21555518, GO:0043565=GO_REF:0000002, GO:0001078=PMID:12511571, GO:0006355=GO_REF:0000024, GO:0000083=PMID:21555518, GO:0003700=GO_REF:0000024, GO:0061418=PMID:12511571, GO:0005634=PMID:12511571, GO:0000122=PMID:21555518, GO:0003677=GO_REF:0000019, GO:0020037=PMID:21555518, GO:0005829=PMID:16780588} O14867 Transcription regulator protein BACH1 protein 20110831 {GO:0000117=IMP, GO:0043565=IEA, GO:0001078=IDA, GO:0006355=ISS, GO:0000083=IMP, GO:0003700=ISS, GO:0061418=IDA, GO:0005634=IDA, GO:0000122=IMP, GO:0003677=IEA, GO:0020037=NAS, GO:0005829=IDA} negative regulation of transcription from RNA polymerase II promoter, regulation of transcription from RNA polymerase II promoter in response to hypoxia, regulation of transcription involved in G1/S phase of mitotic cell cycle, regulation of transcription involved in G2/M-phase of mitotic cell cycle, regulation of transcription, DNA-dependent cytosol, nucleus DNA binding, RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription, heme binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity Human BACH2 UniProtKB UniProtKB {GO:0043565=GO_REF:0000002, GO:0003700=GO_REF:0000019, GO:0005634=GO_REF:0000039, GO:0003677=GO_REF:0000019, GO:0006351=GO_REF:0000037} Q9BYV9 Transcription regulator protein BACH2 protein 20130413 {GO:0043565=IEA, GO:0003700=IEA, GO:0005634=IEA, GO:0003677=IEA, GO:0006351=IEA} transcription, DNA-dependent nucleus DNA binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity Human UniProtKB-SubCell:SL-0191 BAD HPA UniProtKB {GO:0005515=PMID:20603619, GO:0042542=GO_REF:0000019, GO:0030346=GO_REF:0000019, GO:0019221=GO_REF:0000019, GO:0097202=PMID:18387192, GO:0071396=GO_REF:0000019, GO:1900740=Reactome:REACT_697, GO:0007173=Reactome:REACT_9417, GO:0032024=GO_REF:0000024, GO:0032355=GO_REF:0000019, GO:0050679=PMID:19593445, GO:0046034=GO_REF:0000024, GO:0046982=GO_REF:0000019, GO:0019901=PMID:17270021, GO:0046031=GO_REF:0000024, GO:2001244=Reactome:REACT_330, GO:0051384=GO_REF:0000019, GO:0071316=PMID:18676776, GO:0008656=PMID:18402937, GO:0043280=PMID:18402937, GO:0046931=PMID:21081150, GO:0051592=GO_REF:0000019, GO:0071247=GO_REF:0000019, GO:0008543=Reactome:REACT_9470, GO:0045087=Reactome:REACT_6802, GO:2000078=GO_REF:0000024, GO:0032570=GO_REF:0000019, GO:0045471=GO_REF:0000019, GO:0045579=GO_REF:0000019, GO:0005741=Reactome:REACT_21278, GO:0005829=Reactome:REACT_147775, GO:0008289=PMID:19667065, GO:0005739=GO_REF:0000052, GO:0005543=PMID:21081150, GO:0044342=GO_REF:0000024, GO:0006007=GO_REF:0000019, GO:0043200=GO_REF:0000019, GO:0045582=GO_REF:0000019, GO:0001666=GO_REF:0000019, GO:0046902=PMID:20700721, GO:0048011=Reactome:REACT_13776, GO:0043065=PMID:9388232, GO:0035774=GO_REF:0000019, GO:0006919=GO_REF:0000024, GO:0048015=Reactome:REACT_12464, GO:0042493=GO_REF:0000019, GO:0034201=GO_REF:0000019, GO:0006915=Reactome:REACT_13638, GO:0071456=PMID:20810912, GO:0033133=GO_REF:0000024, GO:0042593=GO_REF:0000024, GO:0006917=PMID:19667065, GO:0033574=GO_REF:0000019, GO:0097191=PMID:18852119, GO:0043422=GO_REF:0000019, GO:0097190=Reactome:REACT_13720, GO:0045862=PMID:18387192, GO:0097193=Reactome:REACT_964, GO:0009749=GO_REF:0000019, GO:0010918=GO_REF:0000024, GO:0060154=GO_REF:0000019, GO:0071260=PMID:19593445} Q92934 Bcl2 antagonist of cell death protein 20101115 {GO:0005515=IPI, GO:0042542=IEA, GO:0030346=IEA, GO:0019221=IEA, GO:0097202=IDA, GO:0071396=IEA, GO:1900740=TAS, GO:0007173=TAS, GO:0032024=ISS, GO:0032355=IEA, GO:0050679=IMP, GO:0046034=ISS, GO:0046982=IEA, GO:0019901=IPI, GO:0046031=ISS, GO:2001244=TAS, GO:0051384=IEA, GO:0071316=IDA, GO:0008656=IDA, GO:0043280=IDA, GO:0046931=IDA, GO:0051592=IEA, GO:0071247=IEA, GO:0008543=TAS, GO:0045087=TAS, GO:2000078=ISS, GO:0032570=IEA, GO:0045471=IEA, GO:0045579=IEA, GO:0005741=TAS, GO:0005829=TAS, GO:0008289=IDA, GO:0005739=IDA, GO:0005543=IMP, GO:0044342=ISS, GO:0006007=IEA, GO:0043200=IEA, GO:0045582=IEA, GO:0001666=IEA, GO:0046902=IMP, GO:0048011=TAS, GO:0043065=IDA, GO:0035774=IEA, GO:0006919=ISS, GO:0048015=TAS, GO:0042493=IEA, GO:0034201=IEA, GO:0006915=TAS, GO:0071456=IEP, GO:0033133=ISS, GO:0042593=ISS, GO:0006917=IDA, GO:0033574=IEA, GO:0097191=IMP, GO:0043422=IEA, GO:0097190=TAS, GO:0045862=IDA, GO:0097193=TAS, GO:0009749=IEA, GO:0010918=ISS, GO:0060154=IEA, GO:0071260=IEP} ADP metabolic process, ATP metabolic process, activation of cysteine-type endopeptidase activity, activation of cysteine-type endopeptidase activity involved in apoptotic process, apoptotic process, apoptotic signaling pathway, cellular process regulating host cell cycle in response to virus, cellular response to chromate, cellular response to hypoxia, cellular response to lipid, cellular response to mechanical stimulus, cellular response to nicotine, cytokine-mediated signaling pathway, epidermal growth factor receptor signaling pathway, extrinsic apoptotic signaling pathway, fibroblast growth factor receptor signaling pathway, glucose catabolic process, glucose homeostasis, induction of apoptosis, innate immune response, intrinsic apoptotic signaling pathway, neurotrophin TRK receptor signaling pathway, phosphatidylinositol-mediated signaling, pore complex assembly, positive regulation of B cell differentiation, positive regulation of T cell differentiation, positive regulation of apoptotic process, positive regulation of cysteine-type endopeptidase activity involved in apoptotic process, positive regulation of epithelial cell proliferation, positive regulation of glucokinase activity, positive regulation of insulin secretion, positive regulation of insulin secretion involved in cellular response to glucose stimulus, positive regulation of intrinsic apoptotic signaling pathway, positive regulation of mitochondrial membrane potential, positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway, positive regulation of proteolysis, positive regulation of type B pancreatic cell development, regulation of mitochondrial membrane permeability, response to amino acid stimulus, response to calcium ion, response to drug, response to estradiol stimulus, response to ethanol, response to glucocorticoid stimulus, response to glucose stimulus, response to hydrogen peroxide, response to hypoxia, response to oleic acid, response to progesterone stimulus, response to testosterone stimulus, type B pancreatic cell proliferation cytosol, mitochondrial outer membrane, mitochondrion cysteine-type endopeptidase activator activity involved in apoptotic process, lipid binding, phospholipid binding, protein binding, protein heterodimerization activity, protein kinase B binding, protein kinase binding, protein phosphatase 2B binding Human BAG1 LIFEdb UniProtKB {GO:0051219=GO_REF:0000019, GO:0005515=PMID:9305631, GO:0043066=PMID:8947043, GO:0051087=GO_REF:0000002, GO:0006915=GO_REF:0000037, GO:0005634=GO_REF:0000054, GO:0005829=GO_REF:0000019, GO:0005737=GO_REF:0000039, GO:0043525=GO_REF:0000019, GO:0070389=PMID:12853476, GO:0030182=GO_REF:0000019, GO:0045944=GO_REF:0000019, GO:0005057=PMID:8947043, GO:0007166=PMID:8947043} Q99933 BAG family molecular chaperone regulator 1 protein 20100607 {GO:0051219=IEA, GO:0005515=IPI, GO:0043066=TAS, GO:0051087=IEA, GO:0006915=IEA, GO:0005634=IDA, GO:0005829=IEA, GO:0005737=IEA, GO:0043525=IEA, GO:0070389=IDA, GO:0030182=IEA, GO:0045944=IEA, GO:0005057=TAS, GO:0007166=TAS} apoptotic process, cell surface receptor signaling pathway, chaperone cofactor-dependent protein refolding, negative regulation of apoptotic process, neuron differentiation, positive regulation of neuron apoptotic process, positive regulation of transcription from RNA polymerase II promoter cytoplasm, cytosol, nucleus chaperone binding, phosphoprotein binding, protein binding, receptor signaling protein activity Human BAG2 MGI UniProtKB {GO:0006457=PMID:9873016, GO:0051087=GO_REF:0000002, GO:0019538=PMID:9873015} O95816 BAG family molecular chaperone regulator 2 protein 20060110 {GO:0006457=TAS, GO:0051087=IEA, GO:0019538=IDA} protein folding, protein metabolic process chaperone binding Human BAG3 HPA UniProtKB {GO:0005515=PMID:22366786, GO:0043005=GO_REF:0000019, GO:0043066=PMID:10597216, GO:0005737=GO_REF:0000052, GO:0021510=GO_REF:0000019, GO:0005886=GO_REF:0000052, GO:0006457=PMID:9873016, GO:0007420=GO_REF:0000019, GO:0051087=GO_REF:0000002, GO:0006915=GO_REF:0000037, GO:0032403=GO_REF:0000019, GO:0005829=PMID:10597216} O95817 BAG family molecular chaperone regulator 3 protein 20100326 {GO:0005515=IPI, GO:0043005=IEA, GO:0043066=NAS, GO:0005737=IDA, GO:0021510=IEA, GO:0005886=IDA, GO:0006457=NAS, GO:0007420=IEA, GO:0051087=IEA, GO:0006915=IEA, GO:0032403=IEA, GO:0005829=IDA} apoptotic process, brain development, negative regulation of apoptotic process, protein folding, spinal cord development cytoplasm, cytosol, neuron projection, plasma membrane chaperone binding, protein binding, protein complex binding Human BAG4 HPA UniProtKB {GO:0051897=GO_REF:0000019, GO:0043066=PMID:9915703, GO:2001145=GO_REF:0000019, GO:0005730=GO_REF:0000052, GO:0051087=GO_REF:0000002, GO:0005634=GO_REF:0000052, GO:0072659=GO_REF:0000019, GO:0045785=GO_REF:0000019, GO:0005737=GO_REF:0000052, GO:0033138=GO_REF:0000019, GO:0010763=GO_REF:0000019, GO:0030838=GO_REF:0000019, GO:0006457=PMID:9873016, GO:0071364=GO_REF:0000019, GO:0051496=GO_REF:0000019, GO:0071356=PMID:21712384, GO:0097178=GO_REF:0000019, GO:0005057=PMID:9915703} O95429 BAG family molecular chaperone regulator 4 protein 20100326 {GO:0051897=IEA, GO:0043066=TAS, GO:2001145=IEA, GO:0005730=IDA, GO:0051087=IEA, GO:0005634=IDA, GO:0072659=IEA, GO:0045785=IEA, GO:0005737=IDA, GO:0033138=IEA, GO:0010763=IEA, GO:0030838=IEA, GO:0006457=TAS, GO:0071364=IEA, GO:0051496=IEA, GO:0071356=IDA, GO:0097178=IEA, GO:0005057=TAS} cellular response to epidermal growth factor stimulus, cellular response to tumor necrosis factor, negative regulation of apoptotic process, negative regulation of phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity, positive regulation of actin filament polymerization, positive regulation of cell adhesion, positive regulation of fibroblast migration, positive regulation of peptidyl-serine phosphorylation, positive regulation of protein kinase B signaling cascade, positive regulation of stress fiber assembly, protein folding, protein localization to plasma membrane, ruffle assembly cytoplasm, nucleolus, nucleus chaperone binding, receptor signaling protein activity Human BAG5 BHF-UCL UniProtKB {GO:0090083=PMID:15603737, GO:0048471=PMID:15603737, GO:0016234=PMID:15603737, GO:0006457=PMID:9873016, GO:0070997=PMID:15603737, GO:0051087=PMID:15603737, GO:0061084=PMID:15603737, GO:0051444=PMID:15603737, GO:0031397=PMID:15603737, GO:0031625=PMID:15603737} Q9UL15 BAG family molecular chaperone regulator 5 protein 20100429 {GO:0090083=IMP, GO:0048471=IDA, GO:0016234=IDA, GO:0006457=TAS, GO:0070997=ISS, GO:0051087=IPI, GO:0061084=ISS, GO:0051444=ISS, GO:0031397=ISS, GO:0031625=ISS} negative regulation of protein refolding, negative regulation of protein ubiquitination, negative regulation of ubiquitin-protein ligase activity, neuron death, protein folding, regulation of inclusion body assembly inclusion body, perinuclear region of cytoplasm chaperone binding, ubiquitin protein ligase binding Human UniProtKB:Q5QJC9 BAG6 IntAct UniProtKB {GO:0005515=PMID:21903422, GO:0006511=GO_REF:0000024, GO:0030324=GO_REF:0000024, GO:0005634=PMID:17403783, GO:0032435=GO_REF:0000024, GO:0009790=GO_REF:0000024, GO:0007283=GO_REF:0000024, GO:0030154=GO_REF:0000037, GO:0005829=PMID:17403783, GO:0005737=GO_REF:0000019, GO:0042127=GO_REF:0000019, GO:0006810=GO_REF:0000037, GO:0007130=GO_REF:0000024, GO:0001822=GO_REF:0000024, GO:0050821=GO_REF:0000024, GO:0045861=GO_REF:0000024, GO:0018393=PMID:17403783, GO:0042771=PMID:17403783, GO:0007420=GO_REF:0000024, GO:0070059=GO_REF:0000024, GO:0070628=GO_REF:0000024, GO:0030544=GO_REF:0000019, GO:0043022=PMID:20676083, GO:0071816=PMID:20676083, GO:0071818=PMID:20676083, GO:0031593=GO_REF:0000024, GO:0016568=GO_REF:0000037} P46379 Large proline-rich protein BAG6 protein 20130415 {GO:0005515=IPI, GO:0006511=ISS, GO:0030324=ISS, GO:0005634=IDA, GO:0032435=ISS, GO:0009790=ISS, GO:0007283=ISS, GO:0030154=IEA, GO:0005829=IDA, GO:0005737=IEA, GO:0042127=IEA, GO:0006810=IEA, GO:0007130=ISS, GO:0001822=ISS, GO:0050821=ISS, GO:0045861=ISS, GO:0018393=IDA, GO:0042771=IMP, GO:0007420=ISS, GO:0070059=ISS, GO:0070628=ISS, GO:0030544=IEA, GO:0043022=IDA, GO:0071816=IDA, GO:0071818=IDA, GO:0031593=ISS, GO:0016568=IEA} brain development, cell differentiation, chromatin modification, embryo development, internal peptidyl-lysine acetylation, intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator, intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress, kidney development, lung development, negative regulation of proteasomal ubiquitin-dependent protein catabolic process, negative regulation of proteolysis, protein stabilization, regulation of cell proliferation, spermatogenesis, synaptonemal complex assembly, tail-anchored membrane protein insertion into ER membrane, transport, ubiquitin-dependent protein catabolic process BAT3 complex, cytoplasm, cytosol, nucleus Hsp70 protein binding, polyubiquitin binding, proteasome binding, protein binding, ribosome binding Human UniProtKB:Q7Z434 BAGE3 UniProtKB UniProtKB {GO:0005576=GO_REF:0000039} Q86Y29 B melanoma antigen 3 protein 20130413 {GO:0005576=IEA} extracellular region Human UniProtKB-SubCell:SL-0243 BAHCC1 InterPro UniProtKB {GO:0003677=GO_REF:0000002} Q9P281 BAH and coiled-coil domain-containing protein 1 protein 20130413 {GO:0003677=IEA} DNA binding Human InterPro:IPR001025 BAHD1 UniProtKB UniProtKB {GO:0005515=PMID:19666599, GO:0031507=PMID:19666599, GO:0005694=GO_REF:0000039, GO:0003682=PMID:19666599, GO:0045892=PMID:19666599, GO:0003677=GO_REF:0000002, GO:0006351=GO_REF:0000037, GO:0005677=PMID:19666599} Q8TBE0 Bromo adjacent homology domain-containing 1 protein protein 20091029 {GO:0005515=IPI, GO:0031507=IMP, GO:0005694=IEA, GO:0003682=IDA, GO:0045892=IMP, GO:0003677=IEA, GO:0006351=IEA, GO:0005677=IDA} heterochromatin assembly, negative regulation of transcription, DNA-dependent, transcription, DNA-dependent chromatin silencing complex, chromosome DNA binding, chromatin binding, protein binding Human BAI1 GDB UniProtKB {GO:0008285=PMID:7531056, GO:0005886=PMID:9647739, GO:0004930=GO_REF:0000037, GO:0007409=PMID:10343108, GO:0007165=PMID:9647739, GO:0007186=PMID:15203201, GO:0007218=GO_REF:0000002, GO:0005887=PMID:9647739, GO:0005911=PMID:9647739, GO:0016525=GO_REF:0000002, GO:0007422=PMID:10343108, GO:0016021=PMID:15203201, GO:0007155=GO_REF:0000037} O14514 Brain-specific angiogenesis inhibitor 1 protein 20050509 {GO:0008285=TAS, GO:0005886=TAS, GO:0004930=IEA, GO:0007409=TAS, GO:0007165=TAS, GO:0007186=TAS, GO:0007218=IEA, GO:0005887=TAS, GO:0005911=TAS, GO:0016525=IEA, GO:0007422=TAS, GO:0016021=TAS, GO:0007155=IEA} G-protein coupled receptor signaling pathway, axonogenesis, cell adhesion, negative regulation of angiogenesis, negative regulation of cell proliferation, neuropeptide signaling pathway, peripheral nervous system development, signal transduction cell-cell junction, integral to membrane, integral to plasma membrane, plasma membrane G-protein coupled receptor activity Human BAI2 GDB UniProtKB {GO:0007186=PMID:15203201, GO:0016020=GO_REF:0000002, GO:0005886=GO_REF:0000039, GO:0007218=GO_REF:0000002, GO:0004930=GO_REF:0000037, GO:0007422=GO_REF:0000019, GO:0016525=GO_REF:0000002, GO:0016021=GO_REF:0000037} O60241 Brain-specific angiogenesis inhibitor 2 protein 20050509 {GO:0007186=TAS, GO:0016020=IEA, GO:0005886=IEA, GO:0007218=IEA, GO:0004930=IEA, GO:0007422=IEA, GO:0016525=IEA, GO:0016021=IEA} G-protein coupled receptor signaling pathway, negative regulation of angiogenesis, neuropeptide signaling pathway, peripheral nervous system development integral to membrane, membrane, plasma membrane G-protein coupled receptor activity Human BAI3 GDB UniProtKB {GO:0007186=PMID:15203201, GO:0005886=GO_REF:0000039, GO:0007218=GO_REF:0000002, GO:0004930=GO_REF:0000037, GO:0016525=GO_REF:0000002, GO:0016021=GO_REF:0000037} O60242 Brain-specific angiogenesis inhibitor 3 protein 20050509 {GO:0007186=TAS, GO:0005886=IEA, GO:0007218=IEA, GO:0004930=IEA, GO:0016525=IEA, GO:0016021=IEA} G-protein coupled receptor signaling pathway, negative regulation of angiogenesis, neuropeptide signaling pathway integral to membrane, plasma membrane G-protein coupled receptor activity Human BAIAP2 HPA UniProtKB {GO:0008286=PMID:10343108, GO:0005515=PMID:19171758, GO:0043005=GO_REF:0000019, GO:0017124=GO_REF:0000002, GO:0030054=GO_REF:0000052, GO:0005886=GO_REF:0000052, GO:0008360=GO_REF:0000024, GO:0005634=GO_REF:0000052, GO:0030175=GO_REF:0000039, GO:0007409=PMID:10343108, GO:0015629=PMID:19366662, GO:0042802=PMID:14752106, GO:0005829=Reactome:REACT_160291, GO:0009617=PMID:19366662, GO:0005737=GO_REF:0000052, GO:0048167=GO_REF:0000019, GO:0032956=PMID:19366662, GO:0046847=GO_REF:0000002, GO:0051764=GO_REF:0000024, GO:0051017=GO_REF:0000024, GO:0070064=PMID:19366662, GO:0008093=GO_REF:0000002, GO:0005730=GO_REF:0000052, GO:0008022=PMID:10343108, GO:0001726=GO_REF:0000039, GO:0016358=GO_REF:0000019, GO:0007165=GO_REF:0000002, GO:0045087=Reactome:REACT_6802, GO:0038096=Reactome:REACT_160123} Q9UQB8 Brain-specific angiogenesis inhibitor 1-associated protein 2 protein 20101115 {GO:0008286=TAS, GO:0005515=IPI, GO:0043005=IEA, GO:0017124=IEA, GO:0030054=IDA, GO:0005886=IDA, GO:0008360=ISS, GO:0005634=IDA, GO:0030175=IEA, GO:0007409=TAS, GO:0015629=IDA, GO:0042802=IPI, GO:0005829=TAS, GO:0009617=IMP, GO:0005737=IDA, GO:0048167=IEA, GO:0032956=IMP, GO:0046847=IEA, GO:0051764=ISS, GO:0051017=ISS, GO:0070064=IDA, GO:0008093=IEA, GO:0005730=IDA, GO:0008022=TAS, GO:0001726=IEA, GO:0016358=IEA, GO:0007165=IEA, GO:0045087=TAS, GO:0038096=TAS} Fc-gamma receptor signaling pathway involved in phagocytosis, actin crosslink formation, actin filament bundle assembly, axonogenesis, dendrite development, filopodium assembly, innate immune response, insulin receptor signaling pathway, regulation of actin cytoskeleton organization, regulation of cell shape, regulation of synaptic plasticity, response to bacterium, signal transduction actin cytoskeleton, cell junction, cytoplasm, cytosol, filopodium, neuron projection, nucleolus, nucleus, plasma membrane, ruffle SH3 domain binding, cytoskeletal adaptor activity, identical protein binding, proline-rich region binding, protein C-terminus binding, protein binding Human BAIAP2L1 HPA UniProtKB {GO:0017124=GO_REF:0000002, GO:0030054=GO_REF:0000052, GO:0005886=GO_REF:0000052, GO:0005730=GO_REF:0000052, GO:2000251=PMID:19366662, GO:0003779=GO_REF:0000037, GO:0005634=GO_REF:0000052, GO:0015629=PMID:19366662, GO:0005829=PMID:19366662, GO:0007165=GO_REF:0000002, GO:0009617=PMID:19366662, GO:0005737=GO_REF:0000052, GO:0030838=PMID:21098279, GO:0046847=GO_REF:0000002, GO:0070064=PMID:21098279, GO:0008093=GO_REF:0000002} Q9UHR4 Brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 1 protein 20090616 {GO:0017124=IEA, GO:0030054=IDA, GO:0005886=IDA, GO:0005730=IDA, GO:2000251=IMP, GO:0003779=IEA, GO:0005634=IDA, GO:0015629=IDA, GO:0005829=IDA, GO:0007165=IEA, GO:0009617=IDA, GO:0005737=IDA, GO:0030838=IDA, GO:0046847=IEA, GO:0070064=IDA, GO:0008093=IEA} filopodium assembly, positive regulation of actin cytoskeleton reorganization, positive regulation of actin filament polymerization, response to bacterium, signal transduction actin cytoskeleton, cell junction, cytoplasm, cytosol, nucleolus, nucleus, plasma membrane SH3 domain binding, actin binding, cytoskeletal adaptor activity, proline-rich region binding Human BAIAP2L2 InterPro UniProtKB {GO:0012506=PMID:21743456, GO:0007165=GO_REF:0000002, GO:0017124=GO_REF:0000002, GO:0005543=GO_REF:0000024, GO:0005886=GO_REF:0000039, GO:0071439=PMID:21401524, GO:0044291=PMID:21743456, GO:0046847=GO_REF:0000002, GO:0016044=GO_REF:0000024, GO:0030659=GO_REF:0000039, GO:0008093=GO_REF:0000002} Q9H661 BAI1-associated protein 2-like 2, isoform CRA_b protein 20130413 {GO:0012506=IDA, GO:0007165=IEA, GO:0017124=IEA, GO:0005543=ISS, GO:0005886=IEA, GO:0071439=IDA, GO:0044291=IDA, GO:0046847=IEA, GO:0016044=ISS, GO:0030659=IEA, GO:0008093=IEA} cellular membrane organization, filopodium assembly, signal transduction cell-cell contact zone, clathrin complex, cytoplasmic vesicle membrane, plasma membrane, vesicle membrane SH3 domain binding, cytoskeletal adaptor activity, phospholipid binding Human InterPro:IPR013606 BAIAP3 MGI UniProtKB {GO:0007186=PMID:9790924, GO:0008022=PMID:9790924, GO:0007269=PMID:9790924} O94812 BAI1-associated protein 3 protein 20091111 {GO:0007186=IPI, GO:0008022=TAS, GO:0007269=TAS} G-protein coupled receptor signaling pathway, neurotransmitter secretion protein C-terminus binding Human UniProtKB:O14514 BAK1 BHF-UCL UniProtKB {GO:0005515=PMID:10950869, GO:0043496=PMID:9111042, GO:0014070=GO_REF:0000019, GO:0042542=GO_REF:0000019, GO:0043497=PMID:9111042, GO:0051400=GO_REF:0000019, GO:0010524=GO_REF:0000019, GO:0097202=PMID:18387192, GO:0042803=GO_REF:0000019, GO:0042802=PMID:21041309, GO:0048597=GO_REF:0000019, GO:0034644=GO_REF:0000024, GO:0008053=GO_REF:0000019, GO:0031072=GO_REF:0000019, GO:0002262=GO_REF:0000019, GO:0010332=GO_REF:0000019, GO:0046982=PMID:10837489, GO:0007568=GO_REF:0000019, GO:0010248=PMID:9843949, GO:0046930=PMID:9843949, GO:0010046=GO_REF:0000019, GO:0007420=GO_REF:0000019, GO:0070059=GO_REF:0000019, GO:0031307=GO_REF:0000024, GO:0032471=GO_REF:0000019, GO:0001783=GO_REF:0000019, GO:0008285=GO_REF:0000019, GO:0001782=GO_REF:0000019, GO:0005783=GO_REF:0000019, GO:0008283=GO_REF:0000019, GO:0045471=GO_REF:0000019, GO:0031100=GO_REF:0000019, GO:0060068=GO_REF:0000019, GO:0009620=GO_REF:0000019, GO:0051087=GO_REF:0000019, GO:0005741=Reactome:REACT_6153, GO:0001836=PMID:21041309, GO:0046872=GO_REF:0000037, GO:0005829=GO_REF:0000019, GO:0005739=PMID:9843949, GO:0033137=GO_REF:0000019, GO:0090200=GO_REF:0000019, GO:0051726=GO_REF:0000019, GO:0035108=GO_REF:0000019, GO:0046902=PMID:21041309, GO:0008635=GO_REF:0000019, GO:0043065=PMID:17289999, GO:1901030=Reactome:REACT_707, GO:0042493=GO_REF:0000019, GO:0051881=PMID:9843949, GO:0006915=Reactome:REACT_578, GO:0097190=PMID:15901672, GO:0045862=PMID:18387192, GO:0097193=Reactome:REACT_964, GO:0010225=GO_REF:0000019, GO:0001974=GO_REF:0000019, GO:0031018=GO_REF:0000019, GO:0010629=GO_REF:0000019, GO:0002352=GO_REF:0000019, GO:0071260=PMID:19593445} Q16611 Bcl-2 homologous antagonist/killer protein 20120404 {GO:0005515=IPI, GO:0043496=IDA, GO:0014070=IEA, GO:0042542=IEA, GO:0043497=IDA, GO:0051400=IEA, GO:0010524=IEA, GO:0097202=IDA, GO:0042803=IEA, GO:0042802=IPI, GO:0048597=IEA, GO:0034644=ISS, GO:0008053=IEA, GO:0031072=IEA, GO:0002262=IEA, GO:0010332=IEA, GO:0046982=IPI, GO:0007568=IEA, GO:0010248=IDA, GO:0046930=IDA, GO:0010046=IEA, GO:0007420=IEA, GO:0070059=IEA, GO:0031307=ISS, GO:0032471=IEA, GO:0001783=IEA, GO:0008285=IEA, GO:0001782=IEA, GO:0005783=IEA, GO:0008283=IEA, GO:0045471=IEA, GO:0031100=IEA, GO:0060068=IEA, GO:0009620=IEA, GO:0051087=IEA, GO:0005741=TAS, GO:0001836=IGI, GO:0046872=IEA, GO:0005829=IEA, GO:0005739=IDA, GO:0033137=IEA, GO:0090200=IEA, GO:0051726=IEA, GO:0035108=IEA, GO:0046902=IDA, GO:0008635=IEA, GO:0043065=IMP, GO:1901030=TAS, GO:0042493=IEA, GO:0051881=IDA, GO:0006915=TAS, GO:0097190=IMP, GO:0045862=IDA, GO:0097193=TAS, GO:0010225=IEA, GO:0001974=IEA, GO:0031018=IEA, GO:0010629=IEA, GO:0002352=IEA, GO:0071260=IEP} B cell apoptotic process, B cell homeostasis, B cell negative selection, activation of cysteine-type endopeptidase activity, activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c, aging, apoptotic process, apoptotic signaling pathway, blood vessel remodeling, brain development, cell proliferation, cellular response to UV, cellular response to mechanical stimulus, endocrine pancreas development, establishment or maintenance of transmembrane electrochemical gradient, intrinsic apoptotic signaling pathway, intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress, limb morphogenesis, mitochondrial fusion, myeloid cell homeostasis, negative regulation of cell proliferation, negative regulation of gene expression, negative regulation of peptidyl-serine phosphorylation, organ regeneration, positive regulation of apoptotic process, positive regulation of calcium ion transport into cytosol, positive regulation of mitochondrial outer membrane permeabilization, positive regulation of proteolysis, positive regulation of release of cytochrome c from mitochondria, post-embryonic camera-type eye morphogenesis, reduction of endoplasmic reticulum calcium ion concentration, regulation of cell cycle, regulation of mitochondrial membrane permeability, regulation of mitochondrial membrane potential, regulation of protein heterodimerization activity, regulation of protein homodimerization activity, release of cytochrome c from mitochondria, response to UV-C, response to drug, response to ethanol, response to fungus, response to gamma radiation, response to hydrogen peroxide, response to mycotoxin, response to organic cyclic compound, vagina development cytosol, endoplasmic reticulum, integral to mitochondrial outer membrane, mitochondrial outer membrane, mitochondrion, pore complex BH domain binding, chaperone binding, heat shock protein binding, identical protein binding, metal ion binding, protein binding, protein heterodimerization activity, protein homodimerization activity Human BAMBI BHF-UCL UniProtKB {GO:0008284=PMID:18838381, GO:0005886=PMID:18756595, GO:0008360=PMID:19328798, GO:0090263=PMID:18838381, GO:0010718=PMID:19328798, GO:0035413=PMID:18838381, GO:0032092=PMID:18838381, GO:0005114=PMID:18756595, GO:0005109=PMID:18838381, GO:0005737=PMID:18756595, GO:0016477=PMID:19328798, GO:0007179=Reactome:REACT_120850, GO:0016021=GO_REF:0000037, GO:0045893=PMID:18838381, GO:0030512=PMID:19328798} Q13145 BMP and activin membrane-bound inhibitor homolog protein 20100903 {GO:0008284=IMP, GO:0005886=IDA, GO:0008360=IMP, GO:0090263=IDA, GO:0010718=IMP, GO:0035413=IMP, GO:0032092=IMP, GO:0005114=TAS, GO:0005109=IPI, GO:0005737=IDA, GO:0016477=IDA, GO:0007179=TAS, GO:0016021=IEA, GO:0045893=IDA, GO:0030512=IMP} cell migration, negative regulation of transforming growth factor beta receptor signaling pathway, positive regulation of canonical Wnt receptor signaling pathway, positive regulation of catenin import into nucleus, positive regulation of cell proliferation, positive regulation of epithelial to mesenchymal transition, positive regulation of protein binding, positive regulation of transcription, DNA-dependent, regulation of cell shape, transforming growth factor beta receptor signaling pathway cytoplasm, integral to membrane, plasma membrane frizzled binding, type II transforming growth factor beta receptor binding Human BANF1 Reactome UniProtKB {GO:0005515=PMID:22770216, GO:0007077=Reactome:REACT_160255, GO:0022415=Reactome:REACT_6266, GO:0005694=GO_REF:0000039, GO:0007084=Reactome:REACT_160113, GO:0015074=GO_REF:0000019, GO:0009615=PMID:9465049, GO:0003677=GO_REF:0000037, GO:0005829=Reactome:REACT_160246, GO:0000088=Reactome:REACT_765, GO:0000087=Reactome:REACT_910, GO:0016032=Reactome:REACT_6256, GO:0005654=Reactome:REACT_160221, GO:0000278=Reactome:REACT_152, GO:0000090=Reactome:REACT_1275, GO:0075713=Reactome:REACT_8990} O75531 Barrier-to-autointegration factor protein 20130121 {GO:0005515=IPI, GO:0007077=TAS, GO:0022415=TAS, GO:0005694=IEA, GO:0007084=TAS, GO:0015074=IEA, GO:0009615=TAS, GO:0003677=IEA, GO:0005829=TAS, GO:0000088=TAS, GO:0000087=TAS, GO:0016032=TAS, GO:0005654=TAS, GO:0000278=TAS, GO:0000090=TAS, GO:0075713=TAS} DNA integration, M phase of mitotic cell cycle, establishment of integrated proviral latency, mitotic anaphase, mitotic cell cycle, mitotic nuclear envelope disassembly, mitotic nuclear envelope reassembly, mitotic prophase, response to virus, viral reproduction, viral reproductive process chromosome, cytosol, nucleoplasm DNA binding, protein binding Human BANK1 UniProtKB UniProtKB {GO:0042113=GO_REF:0000037} Q8NDB2 B-cell scaffold protein with ankyrin repeats protein 20130413 {GO:0042113=IEA} B cell activation Human UniProtKB-KW:KW-0075 BANP UniProtKB UniProtKB {GO:0002039=GO_REF:0000019, GO:0007049=GO_REF:0000037, GO:0006355=GO_REF:0000037, GO:0034504=GO_REF:0000019, GO:0042177=GO_REF:0000019, GO:0007275=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037, GO:0016568=GO_REF:0000037} Q8N9N5 Protein BANP protein 20130413 {GO:0002039=IEA, GO:0007049=IEA, GO:0006355=IEA, GO:0034504=IEA, GO:0042177=IEA, GO:0007275=IEA, GO:0005634=IEA, GO:0003677=IEA, GO:0006351=IEA, GO:0016568=IEA} cell cycle, chromatin modification, multicellular organismal development, negative regulation of protein catabolic process, protein localization to nucleus, regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus DNA binding, p53 binding Human UniProtKB-SubCell:SL-0191 BAP1 HPA UniProtKB {GO:0005515=PMID:22897849, GO:0071108=PMID:19188440, GO:0006511=GO_REF:0000002, GO:0016579=PMID:18757409, GO:0008285=PMID:9528852, GO:0004843=PMID:18757409, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0001558=PMID:19815555, GO:0035517=PMID:20436459, GO:0043231=GO_REF:0000052, GO:0005622=GO_REF:0000002, GO:0005737=PMID:19188440, GO:0035522=PMID:20436459, GO:0003682=PMID:19815555, GO:0051726=PMID:19188440, GO:0008233=PMID:9528852, GO:0004221=PMID:19815555, GO:0006464=PMID:9528852} Q92560 Ubiquitin carboxyl-terminal hydrolase BAP1 protein 20120912 {GO:0005515=IPI, GO:0071108=IMP, GO:0006511=IEA, GO:0016579=IDA, GO:0008285=TAS, GO:0004843=IDA, GO:0005730=IDA, GO:0005634=IDA, GO:0001558=IMP, GO:0035517=IDA, GO:0043231=IDA, GO:0005622=IEA, GO:0005737=IDA, GO:0035522=IDA, GO:0003682=IDA, GO:0051726=IMP, GO:0008233=NAS, GO:0004221=IMP, GO:0006464=NAS} cellular protein modification process, monoubiquitinated histone H2A deubiquitination, negative regulation of cell proliferation, protein K48-linked deubiquitination, protein deubiquitination, regulation of cell cycle, regulation of cell growth, ubiquitin-dependent protein catabolic process PR-DUB complex, cytoplasm, intracellular, intracellular membrane-bounded organelle, nucleolus, nucleus chromatin binding, peptidase activity, protein binding, ubiquitin thiolesterase activity, ubiquitin-specific protease activity Human BARD1 IntAct UniProtKB {GO:0005515=PMID:15383276, GO:0085020=PMID:12890688, GO:0043066=PMID:15265711, GO:0045732=PMID:15905410, GO:0004842=PMID:20351172, GO:0043065=PMID:15782130, GO:0016567=PMID:15905410, GO:0046982=PMID:15265711, GO:0003723=PMID:12419249, GO:0000151=PMID:14976165, GO:0005634=PMID:15632137, GO:0031436=PMID:19117993, GO:0042803=PMID:15265711, GO:0006974=PMID:15905410, GO:0070531=PMID:19261749, GO:0042325=PMID:15782130, GO:0046826=PMID:15265711, GO:0005737=PMID:15265711, GO:0006281=GO_REF:0000037, GO:0001894=PMID:15782130, GO:0007050=PMID:15632137, GO:0008270=GO_REF:0000002, GO:0019900=PMID:15782130, GO:0031441=PMID:15905410} Q99728 BRCA1-associated RING domain protein 1 protein 20130415 {GO:0005515=IPI, GO:0085020=IDA, GO:0043066=IMP, GO:0045732=NAS, GO:0004842=IDA, GO:0043065=IMP, GO:0016567=NAS, GO:0046982=IPI, GO:0003723=IDA, GO:0000151=NAS, GO:0005634=IMP, GO:0031436=IDA, GO:0042803=IPI, GO:0006974=NAS, GO:0070531=IDA, GO:0042325=IMP, GO:0046826=IDA, GO:0005737=IDA, GO:0006281=IEA, GO:0001894=TAS, GO:0007050=NAS, GO:0008270=IEA, GO:0019900=NAS, GO:0031441=NAS} DNA repair, cell cycle arrest, negative regulation of apoptotic process, negative regulation of mRNA 3'-end processing, negative regulation of protein export from nucleus, positive regulation of apoptotic process, positive regulation of protein catabolic process, protein K6-linked ubiquitination, protein ubiquitination, regulation of phosphorylation, response to DNA damage stimulus, tissue homeostasis BRCA1-A complex, BRCA1-BARD1 complex, cytoplasm, nucleus, ubiquitin ligase complex RNA binding, kinase binding, protein binding, protein heterodimerization activity, protein homodimerization activity, ubiquitin-protein ligase activity, zinc ion binding Human UniProtKB:Q9Y2X7 BARHL1 UniProtKB UniProtKB {GO:0043565=GO_REF:0000002, GO:0043524=GO_REF:0000019, GO:0001077=GO_REF:0000019, GO:0007605=GO_REF:0000019, GO:0005634=GO_REF:0000039, GO:0030901=GO_REF:0000019, GO:0001764=GO_REF:0000019} Q9BZE3 BarH-like 1 homeobox protein protein 20130413 {GO:0043565=IEA, GO:0043524=IEA, GO:0001077=IEA, GO:0007605=IEA, GO:0005634=IEA, GO:0030901=IEA, GO:0001764=IEA} midbrain development, negative regulation of neuron apoptotic process, neuron migration, sensory perception of sound nucleus RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription, sequence-specific DNA binding Human UniProtKB-SubCell:SL-0191 BARX1 UniProtKB UniProtKB {GO:0055123=GO_REF:0000019, GO:0006355=GO_REF:0000029, GO:0000976=GO_REF:0000002, GO:0003700=PMID:10995576, GO:0030855=GO_REF:0000019, GO:0030178=GO_REF:0000019, GO:0007267=GO_REF:0000019, GO:0007275=GO_REF:0000029, GO:0000228=GO_REF:0000029, GO:0048536=GO_REF:0000019, GO:0009952=GO_REF:0000019, GO:0006351=GO_REF:0000037} Q9HBU1 Homeobox protein BarH-like 1 protein 20021104 {GO:0055123=IEA, GO:0006355=NAS, GO:0000976=IEA, GO:0003700=NAS, GO:0030855=IEA, GO:0030178=IEA, GO:0007267=IEA, GO:0007275=NAS, GO:0000228=NAS, GO:0048536=IEA, GO:0009952=IEA, GO:0006351=IEA} anterior/posterior pattern specification, cell-cell signaling, digestive system development, epithelial cell differentiation, multicellular organismal development, negative regulation of Wnt receptor signaling pathway, regulation of transcription, DNA-dependent, spleen development, transcription, DNA-dependent nuclear chromosome sequence-specific DNA binding transcription factor activity, transcription regulatory region sequence-specific DNA binding Human BARX2 MGI UniProtKB {GO:0005667=GO_REF:0000019, GO:0014902=GO_REF:0000019, GO:0000976=GO_REF:0000002, GO:0003700=GO_REF:0000019, GO:0001502=GO_REF:0000019, GO:0045944=GO_REF:0000019, GO:0003682=GO_REF:0000019, GO:0005634=GO_REF:0000040, GO:0000122=GO_REF:0000019, GO:0003677=PMID:10854790, GO:0006351=GO_REF:0000037, GO:0042637=GO_REF:0000019} Q9UMQ3 Homeobox protein BarH-like 2 protein 20080305 {GO:0005667=IEA, GO:0014902=IEA, GO:0000976=IEA, GO:0003700=IEA, GO:0001502=IEA, GO:0045944=IEA, GO:0003682=IEA, GO:0005634=IEA, GO:0000122=IEA, GO:0003677=IDA, GO:0006351=IEA, GO:0042637=IEA} cartilage condensation, catagen, myotube differentiation, negative regulation of transcription from RNA polymerase II promoter, positive regulation of transcription from RNA polymerase II promoter, transcription, DNA-dependent nucleus, transcription factor complex DNA binding, chromatin binding, sequence-specific DNA binding transcription factor activity, transcription regulatory region sequence-specific DNA binding Human BASP1 PINC UniProtKB {GO:0008406=GO_REF:0000024, GO:0005515=PMID:19050011, GO:0072112=GO_REF:0000024, GO:0005886=GO_REF:0000039, GO:0044212=GO_REF:0000024, GO:0003714=PMID:14701728, GO:0019904=PMID:14701728, GO:0007356=GO_REF:0000024, GO:0060231=GO_REF:0000024, GO:0060421=GO_REF:0000024, GO:0005634=PMID:14701728, GO:0072075=GO_REF:0000024, GO:0030426=GO_REF:0000039, GO:0005737=PMID:14701728, GO:0008180=PMID:18850735, GO:0016607=GO_REF:0000024, GO:0060539=GO_REF:0000024, GO:2001076=GO_REF:0000024, GO:0005856=PMID:9749536, GO:0045892=PMID:19050011} P80723 Brain acid soluble protein 1 protein 20030904 {GO:0008406=ISS, GO:0005515=IPI, GO:0072112=ISS, GO:0005886=IEA, GO:0044212=ISS, GO:0003714=IMP, GO:0019904=IPI, GO:0007356=ISS, GO:0060231=ISS, GO:0060421=ISS, GO:0005634=IDA, GO:0072075=ISS, GO:0030426=IEA, GO:0005737=IDA, GO:0008180=IDA, GO:0016607=ISS, GO:0060539=ISS, GO:2001076=ISS, GO:0005856=TAS, GO:0045892=IDA} diaphragm development, glomerular visceral epithelial cell differentiation, gonad development, mesenchymal to epithelial transition, metanephric mesenchyme development, negative regulation of transcription, DNA-dependent, positive regulation of heart growth, positive regulation of metanephric ureteric bud development, thorax and anterior abdomen determination cytoplasm, cytoskeleton, growth cone, nuclear speck, nucleus, plasma membrane, signalosome protein binding, protein domain specific binding, transcription corepressor activity, transcription regulatory region DNA binding Human BATF UniProtKB UniProtKB {GO:0005515=PMID:8954125, GO:0002320=GO_REF:0000024, GO:0003700=GO_REF:0000024, GO:0030330=GO_REF:0000024, GO:0072539=GO_REF:0000024, GO:0045190=GO_REF:0000024, GO:0042832=GO_REF:0000024, GO:0005634=GO_REF:0000024, GO:0001816=GO_REF:0000024, GO:0060218=GO_REF:0000024, GO:0072540=GO_REF:0000024, GO:0006351=GO_REF:0000037, GO:0006974=GO_REF:0000024, GO:0043565=GO_REF:0000024, GO:0005737=GO_REF:0000024, GO:0045064=GO_REF:0000024, GO:0043011=GO_REF:0000024} Q16520 Basic leucine zipper transcriptional factor ATF-like protein 20121102 {GO:0005515=IPI, GO:0002320=ISS, GO:0003700=ISS, GO:0030330=ISS, GO:0072539=ISS, GO:0045190=ISS, GO:0042832=ISS, GO:0005634=ISS, GO:0001816=ISS, GO:0060218=ISS, GO:0072540=ISS, GO:0006351=IEA, GO:0006974=ISS, GO:0043565=ISS, GO:0005737=ISS, GO:0045064=ISS, GO:0043011=ISS} DNA damage response, signal transduction by p53 class mediator, T-helper 17 cell differentiation, T-helper 17 cell lineage commitment, T-helper 2 cell differentiation, cytokine production, defense response to protozoan, hematopoietic stem cell differentiation, isotype switching, lymphoid progenitor cell differentiation, myeloid dendritic cell differentiation, response to DNA damage stimulus, transcription, DNA-dependent cytoplasm, nucleus protein binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity Human UniProtKB:O35284 BATF2 IntAct UniProtKB {GO:0005515=PMID:21988832, GO:0043565=GO_REF:0000002, GO:0003700=GO_REF:0000002, GO:0042832=GO_REF:0000024, GO:0005634=GO_REF:0000039, GO:0043011=GO_REF:0000024, GO:0006351=GO_REF:0000037} Q8N1L9 Basic leucine zipper transcriptional factor ATF-like 2 protein 20130415 {GO:0005515=IPI, GO:0043565=IEA, GO:0003700=IEA, GO:0042832=ISS, GO:0005634=IEA, GO:0043011=ISS, GO:0006351=IEA} defense response to protozoan, myeloid dendritic cell differentiation, transcription, DNA-dependent nucleus protein binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity Human UniProtKB:P17275 BATF3 PINC UniProtKB {GO:0043565=GO_REF:0000002, GO:0003700=GO_REF:0000002, GO:0006366=PMID:10878360, GO:0003714=PMID:10878360, GO:0005634=GO_REF:0000039, GO:0043011=GO_REF:0000024, GO:0097028=GO_REF:0000024, GO:0009615=GO_REF:0000024} Q9NR55 Basic leucine zipper transcriptional factor ATF-like 3 protein 20030904 {GO:0043565=IEA, GO:0003700=IEA, GO:0006366=TAS, GO:0003714=TAS, GO:0005634=IEA, GO:0043011=ISS, GO:0097028=ISS, GO:0009615=ISS} dendritic cell differentiation, myeloid dendritic cell differentiation, response to virus, transcription from RNA polymerase II promoter nucleus sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, transcription corepressor activity Human BAX BHF-UCL UniProtKB {GO:0043496=PMID:9111042, GO:0005515=PMID:16113678, GO:0002358=GO_REF:0000019, GO:0043497=PMID:9111042, GO:0009651=GO_REF:0000019, GO:0060041=GO_REF:0000019, GO:0051402=GO_REF:0000019, GO:0007281=GO_REF:0000019, GO:0048678=GO_REF:0000019, GO:0042803=PMID:9111042, GO:0006808=GO_REF:0000019, GO:0035234=GO_REF:0000019, GO:0042802=PMID:16113678, GO:0048597=GO_REF:0000019, GO:0005757=PMID:9843949, GO:0034644=GO_REF:0000019, GO:0043524=GO_REF:0000019, GO:0008053=PMID:14769861, GO:0008637=PMID:9843949, GO:0043525=PMID:15637643, GO:0097136=PMID:21199865, GO:0002904=GO_REF:0000019, GO:0051260=PMID:14522999, GO:0002262=GO_REF:0000019, GO:0010332=GO_REF:0000019, GO:0046982=PMID:9111042, GO:0006687=GO_REF:0000019, GO:0071310=GO_REF:0000019, GO:0001844=GO_REF:0000019, GO:0009636=PMID:16307838, GO:2001244=PMID:14963330, GO:0010248=PMID:9843949, GO:0009566=GO_REF:0000019, GO:0033599=GO_REF:0000019, GO:0046930=PMID:9219694, GO:0070059=PMID:16645094, GO:0005789=PMID:16424160, GO:0030264=PMID:11350920, GO:1990009=PMID:10702418, GO:0032471=GO_REF:0000019, GO:0032091=PMID:9388232, GO:0001783=PMID:16424160, GO:0021987=GO_REF:0000019, GO:0001782=GO_REF:0000019, GO:0005783=PMID:16424160, GO:0060068=GO_REF:0000019, GO:0006927=PMID:10739008, GO:0048147=GO_REF:0000019, GO:0048515=GO_REF:0000019, GO:0005634=PMID:15102863, GO:0005741=Reactome:REACT_1286, GO:0001836=PMID:9843949, GO:0006922=PMID:11350920, GO:0008289=PMID:14522999, GO:0005829=PMID:17823127, GO:0005739=PMID:17823127, GO:0048087=GO_REF:0000019, GO:0001541=GO_REF:0000019, GO:0048873=GO_REF:0000019, GO:0032976=PMID:9843949, GO:0033137=GO_REF:0000019, GO:0001777=GO_REF:0000019, GO:0051726=GO_REF:0000019, GO:0001101=GO_REF:0000019, GO:0042475=GO_REF:0000019, GO:0051281=GO_REF:0000019, GO:0035108=GO_REF:0000019, GO:0008635=PMID:15214043, GO:0043065=PMID:17289999, GO:0060058=GO_REF:0000019, GO:0006919=PMID:11912183, GO:0051434=PMID:17052454, GO:0001822=GO_REF:0000019, GO:1901030=Reactome:REACT_584, GO:0051881=PMID:9843949, GO:0006915=PMID:9219694, GO:0045136=GO_REF:0000019, GO:0006917=PMID:11912183, GO:0021854=GO_REF:0000019, GO:0043653=PMID:12499352, GO:0097190=PMID:16424160, GO:0097193=Reactome:REACT_964, GO:0006974=GO_REF:0000019, GO:0044445=GO_REF:0000019, GO:0006309=PMID:11350920, GO:0001974=GO_REF:0000019, GO:0019048=GO_REF:0000037, GO:0046666=GO_REF:0000019, GO:0002352=GO_REF:0000019, GO:0001764=GO_REF:0000019, GO:0060011=GO_REF:0000019, GO:0015267=PMID:9219694} Q07812 Apoptosis regulator BAX protein 20080718 {GO:0043496=IDA, GO:0005515=IPI, GO:0002358=IEA, GO:0043497=IPI, GO:0009651=IEA, GO:0060041=IEA, GO:0051402=IEA, GO:0007281=IEA, GO:0048678=IEA, GO:0042803=IPI, GO:0006808=IEA, GO:0035234=IEA, GO:0042802=IPI, GO:0048597=IEA, GO:0005757=IDA, GO:0034644=IEA, GO:0043524=IEA, GO:0008053=IDA, GO:0008637=IDA, GO:0043525=IDA, GO:0097136=IDA, GO:0002904=IEA, GO:0051260=IDA, GO:0002262=IEA, GO:0010332=IEA, GO:0046982=IPI, GO:0006687=IEA, GO:0071310=IEA, GO:0001844=IEA, GO:0009636=IDA, GO:2001244=IMP, GO:0010248=IDA, GO:0009566=IEA, GO:0033599=IEA, GO:0046930=IDA, GO:0070059=IMP, GO:0005789=IDA, GO:0030264=IMP, GO:1990009=IMP, GO:0032471=IEA, GO:0032091=IDA, GO:0001783=IDA, GO:0021987=IEA, GO:0001782=IEA, GO:0005783=IDA, GO:0060068=IEA, GO:0006927=IMP, GO:0048147=IEA, GO:0048515=IEA, GO:0005634=IMP, GO:0005741=TAS, GO:0001836=IDA, GO:0006922=IMP, GO:0008289=IDA, GO:0005829=IDA, GO:0005739=IDA, GO:0048087=IEA, GO:0001541=IEA, GO:0048873=IEA, GO:0032976=IDA, GO:0033137=IEA, GO:0001777=IEA, GO:0051726=IEA, GO:0001101=IEA, GO:0042475=IEA, GO:0051281=IEA, GO:0035108=IEA, GO:0008635=IDA, GO:0043065=IMP, GO:0060058=IEA, GO:0006919=IDA, GO:0051434=IPI, GO:0001822=IEA, GO:1901030=TAS, GO:0051881=IDA, GO:0006915=IDA, GO:0045136=IEA, GO:0006917=IDA, GO:0021854=IEA, GO:0043653=IDA, GO:0097190=IDA, GO:0097193=TAS, GO:0006974=IEA, GO:0044445=IEA, GO:0006309=IMP, GO:0001974=IEA, GO:0019048=IEA, GO:0046666=IEA, GO:0002352=IEA, GO:0001764=IEA, GO:0060011=IEA, GO:0015267=IDA} B cell apoptotic process, B cell homeostasis, B cell homeostatic proliferation, B cell negative selection, Sertoli cell proliferation, T cell homeostatic proliferation, activation of cysteine-type endopeptidase activity involved in apoptotic process, activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c, apoptotic DNA fragmentation, apoptotic mitochondrial changes, apoptotic process, apoptotic signaling pathway, blood vessel remodeling, cellular response to UV, cellular response to organic substance, cerebral cortex development, cleavage of lamin involved in execution phase of apoptosis, development of secondary sexual characteristics, establishment or maintenance of transmembrane electrochemical gradient, fertilization, germ cell development, germ cell programmed cell death, glycosphingolipid metabolic process, homeostasis of number of cells within a tissue, hypothalamus development, induction of apoptosis, intrinsic apoptotic signaling pathway, intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress, kidney development, limb morphogenesis, mitochondrial fragmentation involved in apoptotic process, mitochondrial fusion, myeloid cell homeostasis, negative regulation of fibroblast proliferation, negative regulation of neuron apoptotic process, negative regulation of peptidyl-serine phosphorylation, negative regulation of protein binding, neuron apoptotic process, neuron migration, nuclear fragmentation involved in apoptotic nuclear change, odontogenesis of dentin-containing tooth, ovarian follicle development, positive regulation of B cell apoptotic process, positive regulation of apoptotic process, positive regulation of apoptotic process involved in mammary gland involution, positive regulation of developmental pigmentation, positive regulation of intrinsic apoptotic signaling pathway, positive regulation of mitochondrial outer membrane permeabilization, positive regulation of neuron apoptotic process, positive regulation of release of sequestered calcium ion into cytosol, post-embryonic camera-type eye morphogenesis, protein homooligomerization, protein insertion into mitochondrial membrane involved in apoptotic signaling pathway, reduction of endoplasmic reticulum calcium ion concentration, regulation of cell cycle, regulation of mammary gland epithelial cell proliferation, regulation of mitochondrial membrane potential, regulation of nitrogen utilization, regulation of protein heterodimerization activity, regulation of protein homodimerization activity, release of cytochrome c from mitochondria, release of matrix enzymes from mitochondria, response to DNA damage stimulus, response to acid, response to axon injury, response to gamma radiation, response to salt stress, response to toxic substance, retina development in camera-type eye, retinal cell apoptotic process, retinal cell programmed cell death, spermatid differentiation, transformed cell apoptotic process, vagina development, virus-host interaction Bcl-2 family protein complex, cytosol, cytosolic part, endoplasmic reticulum, endoplasmic reticulum membrane, mitochondrial outer membrane, mitochondrial permeability transition pore complex, mitochondrion, nucleus, pore complex BH3 domain binding, channel activity, identical protein binding, lipid binding, protein binding, protein heterodimerization activity, protein homodimerization activity Human BAZ1A BHF-UCL UniProtKB {GO:0005515=PMID:17519354, GO:0006261=PMID:12434153, GO:0006355=PMID:10662543, GO:0008623=PMID:10880450, GO:0016590=PMID:10662543, GO:0006338=PMID:10662543, GO:0008270=GO_REF:0000002, GO:0000228=GO_REF:0000019, GO:0006351=PMID:10662543, GO:0004402=PMID:10662543} Q9NRL2 Bromodomain adjacent to zinc finger domain protein 1A protein 20100527 {GO:0005515=IPI, GO:0006261=IDA, GO:0006355=NAS, GO:0008623=IDA, GO:0016590=TAS, GO:0006338=TAS, GO:0008270=IEA, GO:0000228=IEA, GO:0006351=NAS, GO:0004402=TAS} DNA-dependent DNA replication, chromatin remodeling, regulation of transcription, DNA-dependent, transcription, DNA-dependent ACF complex, CHRAC, nuclear chromosome histone acetyltransferase activity, protein binding, zinc ion binding Human BAZ1B BHF-UCL UniProtKB {GO:0005515=PMID:19776015, GO:0000793=GO_REF:0000019, GO:0071778=PMID:12837248, GO:0006302=GO_REF:0000024, GO:0071884=PMID:12837248, GO:0042809=PMID:12837248, GO:0034725=PMID:12837248, GO:0070577=PMID:16252006, GO:0043596=PMID:15543136, GO:0006355=GO_REF:0000024, GO:0043044=PMID:12837248, GO:0016572=PMID:19092802, GO:0006337=PMID:12837248, GO:0005524=GO_REF:0000037, GO:0006974=PMID:19092802, GO:0006351=PMID:10662543, GO:0003007=GO_REF:0000024, GO:0032947=PMID:12837248, GO:0035173=PMID:19092802, GO:0005721=GO_REF:0000019, GO:0003682=PMID:16252006, GO:0008270=PMID:11124022, GO:0004713=PMID:19092802, GO:0004715=GO_REF:0000003, GO:0048096=GO_REF:0000024} Q9UIG0 Tyrosine-protein kinase BAZ1B protein 20100624 {GO:0005515=IPI, GO:0000793=IEA, GO:0071778=IDA, GO:0006302=ISS, GO:0071884=IMP, GO:0042809=IPI, GO:0034725=IMP, GO:0070577=IDA, GO:0043596=IDA, GO:0006355=ISS, GO:0043044=IDA, GO:0016572=IDA, GO:0006337=IDA, GO:0005524=IEA, GO:0006974=IDA, GO:0006351=NAS, GO:0003007=ISS, GO:0032947=IDA, GO:0035173=IDA, GO:0005721=IEA, GO:0003682=IDA, GO:0008270=NAS, GO:0004713=IDA, GO:0004715=IEA, GO:0048096=ISS} ATP-dependent chromatin remodeling, DNA replication-dependent nucleosome disassembly, chromatin-mediated maintenance of transcription, double-strand break repair, heart morphogenesis, histone phosphorylation, nucleosome disassembly, regulation of transcription, DNA-dependent, response to DNA damage stimulus, transcription, DNA-dependent WINAC complex, centromeric heterochromatin, condensed chromosome, nuclear replication fork ATP binding, chromatin binding, histone acetyl-lysine binding, histone kinase activity, non-membrane spanning protein tyrosine kinase activity, protein binding, protein complex scaffold, protein tyrosine kinase activity, vitamin D receptor activator activity, vitamin D receptor binding, zinc ion binding Human UniProtKB:Q9Z277 BAZ2A BHF-UCL UniProtKB {GO:0005515=PMID:17474147, GO:0016922=PMID:10662543, GO:0016575=GO_REF:0000024, GO:0070933=GO_REF:0000019, GO:0006355=PMID:10662543, GO:0034770=GO_REF:0000019, GO:0003723=GO_REF:0000024, GO:0005730=GO_REF:0000024, GO:0033553=GO_REF:0000024, GO:0070869=GO_REF:0000019, GO:0005634=GO_REF:0000002, GO:0003677=GO_REF:0000019, GO:0006351=PMID:10662543, GO:0006306=GO_REF:0000024, GO:0000183=GO_REF:0000024, GO:0006338=PMID:11532953, GO:0070577=GO_REF:0000024, GO:0008270=GO_REF:0000002, GO:0005677=GO_REF:0000024, GO:0051567=GO_REF:0000019} Q9UIF9 Bromodomain adjacent to zinc finger domain protein 2A protein 20100527 {GO:0005515=IPI, GO:0016922=NAS, GO:0016575=ISS, GO:0070933=IEA, GO:0006355=NAS, GO:0034770=IEA, GO:0003723=ISS, GO:0005730=ISS, GO:0033553=ISS, GO:0070869=IEA, GO:0005634=IEA, GO:0003677=IEA, GO:0006351=NAS, GO:0006306=ISS, GO:0000183=ISS, GO:0006338=NAS, GO:0070577=ISS, GO:0008270=IEA, GO:0005677=ISS, GO:0051567=IEA} DNA methylation, chromatin remodeling, chromatin silencing at rDNA, heterochromatin assembly involved in chromatin silencing, histone H3-K9 methylation, histone H4 deacetylation, histone H4-K20 methylation, histone deacetylation, regulation of transcription, DNA-dependent, transcription, DNA-dependent chromatin silencing complex, nucleolus, nucleus, rDNA heterochromatin DNA binding, RNA binding, histone acetyl-lysine binding, ligand-dependent nuclear receptor binding, protein binding, zinc ion binding Human BAZ2B BHF-UCL UniProtKB {GO:0005515=PMID:10662543, GO:0006355=PMID:10662543, GO:0008270=GO_REF:0000002, GO:0005634=GO_REF:0000039, GO:0003677=GO_REF:0000037, GO:0006351=PMID:10662543} Q9UIF8 Bromodomain adjacent to zinc finger domain protein 2B protein 20100527 {GO:0005515=IPI, GO:0006355=NAS, GO:0008270=IEA, GO:0005634=IEA, GO:0003677=IEA, GO:0006351=NAS} regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus DNA binding, protein binding, zinc ion binding Human BBC3 BHF-UCL UniProtKB {GO:0005515=PMID:22516262, GO:0032464=PMID:21041309, GO:0034976=PMID:22761832, GO:2001056=GO_REF:0000024, GO:0051209=PMID:17024184, GO:0006919=PMID:17024184, GO:0070245=GO_REF:0000024, GO:0006915=Reactome:REACT_578, GO:0071456=PMID:20810912, GO:0005741=Reactome:REACT_21389, GO:0001836=PMID:11463392, GO:2001244=Reactome:REACT_330, GO:0006917=PMID:16608847, GO:0008340=GO_REF:0000024, GO:0097193=Reactome:REACT_964, GO:0005829=Reactome:REACT_1555, GO:0005739=PMID:11463392, GO:0042771=GO_REF:0000024, GO:0043525=GO_REF:0000024, GO:1900740=Reactome:REACT_697, GO:0070059=GO_REF:0000024, GO:0090200=PMID:21041309, GO:0032471=PMID:17024184, GO:0045926=PMID:11463392} Q9BXH1 Bcl-2-binding component 3 protein 20110317 {GO:0005515=IPI, GO:0032464=IDA, GO:0034976=IDA, GO:2001056=ISS, GO:0051209=IDA, GO:0006919=IDA, GO:0070245=ISS, GO:0006915=TAS, GO:0071456=IEP, GO:0005741=TAS, GO:0001836=IDA, GO:2001244=TAS, GO:0006917=IDA, GO:0008340=ISS, GO:0097193=TAS, GO:0005829=TAS, GO:0005739=IDA, GO:0042771=ISS, GO:0043525=ISS, GO:1900740=TAS, GO:0070059=ISS, GO:0090200=IGI, GO:0032471=IDA, GO:0045926=IMP} activation of cysteine-type endopeptidase activity involved in apoptotic process, apoptotic process, cellular response to hypoxia, determination of adult lifespan, induction of apoptosis, intrinsic apoptotic signaling pathway, intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator, intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress, negative regulation of growth, positive regulation of cysteine-type endopeptidase activity, positive regulation of intrinsic apoptotic signaling pathway, positive regulation of neuron apoptotic process, positive regulation of protein homooligomerization, positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway, positive regulation of release of cytochrome c from mitochondria, positive regulation of thymocyte apoptotic process, reduction of endoplasmic reticulum calcium ion concentration, release of cytochrome c from mitochondria, release of sequestered calcium ion into cytosol, response to endoplasmic reticulum stress cytosol, mitochondrial outer membrane, mitochondrion protein binding Human BBOX1 HPA UniProtKB {GO:0005739=GO_REF:0000019, GO:0034641=Reactome:REACT_13, GO:0008336=Reactome:REACT_417, GO:0005506=GO_REF:0000002, GO:0045329=Reactome:REACT_2125, GO:0008270=PMID:20599753, GO:0044281=Reactome:REACT_111217, GO:0015629=GO_REF:0000052, GO:0016702=GO_REF:0000037, GO:0043231=GO_REF:0000052, GO:0005829=Reactome:REACT_417} O75936 Gamma-butyrobetaine dioxygenase protein 20101115 {GO:0005739=IEA, GO:0034641=TAS, GO:0008336=TAS, GO:0005506=IEA, GO:0045329=TAS, GO:0008270=IDA, GO:0044281=TAS, GO:0015629=IDA, GO:0016702=IEA, GO:0043231=IDA, GO:0005829=TAS} carnitine biosynthetic process, cellular nitrogen compound metabolic process, small molecule metabolic process actin cytoskeleton, cytosol, intracellular membrane-bounded organelle, mitochondrion gamma-butyrobetaine dioxygenase activity, iron ion binding, oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen, zinc ion binding Human BBS1 BHF-UCL UniProtKB {GO:0005515=PMID:17574030, GO:0042384=PMID:17574030, GO:0034464=PMID:17574030, GO:0060170=GO_REF:0000039, GO:0005737=GO_REF:0000039, GO:0001895=PMID:17980398, GO:0043001=PMID:19150989, GO:0045494=PMID:17980398, GO:0035058=PMID:17980398, GO:0050896=GO_REF:0000037} Q8NFJ9 Bardet-Biedl syndrome 1 protein protein 20080521 {GO:0005515=IPI, GO:0042384=IMP, GO:0034464=IDA, GO:0060170=IEA, GO:0005737=IEA, GO:0001895=IMP, GO:0043001=IMP, GO:0045494=IMP, GO:0035058=IMP, GO:0050896=IEA} Golgi to plasma membrane protein transport, cilium assembly, nonmotile primary cilium assembly, photoreceptor cell maintenance, response to stimulus, retina homeostasis BBSome, cilium membrane, cytoplasm protein binding Human BBS10 BHF-UCL UniProtKB {GO:0005515=PMID:20080638, GO:0005929=GO_REF:0000039, GO:0001895=PMID:17980398, GO:0043254=PMID:22500027, GO:0045494=PMID:17980398, GO:0035058=PMID:17980398, GO:0051131=PMID:20080638, GO:0005524=GO_REF:0000037, GO:0044267=GO_REF:0000002, GO:0050896=GO_REF:0000037} Q8TAM1 Bardet-Biedl syndrome 10 protein protein 20080514 {GO:0005515=IPI, GO:0005929=IEA, GO:0001895=IMP, GO:0043254=IMP, GO:0045494=IMP, GO:0035058=IMP, GO:0051131=IMP, GO:0005524=IEA, GO:0044267=IEA, GO:0050896=IEA} cellular protein metabolic process, chaperone-mediated protein complex assembly, nonmotile primary cilium assembly, photoreceptor cell maintenance, regulation of protein complex assembly, response to stimulus, retina homeostasis cilium ATP binding, protein binding Human BBS2 BHF-UCL UniProtKB {GO:0005515=PMID:18000879, GO:0038108=GO_REF:0000024, GO:0060170=GO_REF:0000039, GO:0034464=PMID:17574030, GO:0021987=GO_REF:0000024, GO:0033365=GO_REF:0000024, GO:0043001=PMID:19150989, GO:0031514=PMID:18299575, GO:0007288=GO_REF:0000024, GO:0045494=GO_REF:0000024, GO:0032402=GO_REF:0000024, GO:0048854=GO_REF:0000024, GO:0060296=GO_REF:0000024, GO:0021756=GO_REF:0000024, GO:0021766=GO_REF:0000024, GO:0005737=GO_REF:0000039, GO:0008104=GO_REF:0000024, GO:0040015=GO_REF:0000024, GO:0060271=GO_REF:0000024, GO:0010629=GO_REF:0000019, GO:0045444=GO_REF:0000024, GO:0030534=GO_REF:0000024, GO:0005932=PMID:18299575, GO:0040018=GO_REF:0000019} Q9BXC9 Bardet-Biedl syndrome 2 protein protein 20080903 {GO:0005515=IPI, GO:0038108=ISS, GO:0060170=IEA, GO:0034464=IDA, GO:0021987=ISS, GO:0033365=ISS, GO:0043001=IMP, GO:0031514=IDA, GO:0007288=ISS, GO:0045494=ISS, GO:0032402=ISS, GO:0048854=ISS, GO:0060296=ISS, GO:0021756=ISS, GO:0021766=ISS, GO:0005737=IEA, GO:0008104=ISS, GO:0040015=ISS, GO:0060271=ISS, GO:0010629=IEA, GO:0045444=ISS, GO:0030534=ISS, GO:0005932=IDA, GO:0040018=IEA} Golgi to plasma membrane protein transport, adult behavior, brain morphogenesis, cerebral cortex development, cilium morphogenesis, fat cell differentiation, hippocampus development, melanosome transport, negative regulation of appetite by leptin-mediated signaling pathway, negative regulation of gene expression, negative regulation of multicellular organism growth, photoreceptor cell maintenance, positive regulation of multicellular organism growth, protein localization, protein localization to organelle, regulation of cilium beat frequency involved in ciliary motility, sperm axoneme assembly, striatum development BBSome, cilium membrane, cytoplasm, microtubule basal body, motile cilium protein binding Human UniProtKB:Q98SP7 BBS4 HPA UniProtKB {GO:0005515=PMID:17574030, GO:0007608=GO_REF:0000024, GO:0034452=PMID:15107855, GO:0034451=PMID:15107855, GO:0007286=GO_REF:0000024, GO:0045494=GO_REF:0000024, GO:0032402=GO_REF:0000024, GO:0051877=GO_REF:0000024, GO:0001947=GO_REF:0000024, GO:0001895=GO_REF:0000024, GO:0045444=GO_REF:0000024, GO:0030534=GO_REF:0000024, GO:0005932=PMID:15107855, GO:0003085=GO_REF:0000019, GO:0000242=PMID:15107855, GO:0005813=PMID:14520415, GO:0032465=PMID:15107855, GO:0005814=PMID:15107855, GO:0046548=GO_REF:0000024, GO:0048487=PMID:17574030, GO:0001843=GO_REF:0000024, GO:0016358=GO_REF:0000024, GO:0019216=GO_REF:0000024, GO:0051457=PMID:15107855, GO:0060271=GO_REF:0000024, GO:0038108=GO_REF:0000024, GO:0060170=PMID:17574030, GO:0021987=GO_REF:0000024, GO:0005737=GO_REF:0000052, GO:0060027=GO_REF:0000024, GO:0040018=GO_REF:0000019, GO:0034464=PMID:17574030, GO:0033365=GO_REF:0000024, GO:0043014=PMID:17574030, GO:0031514=PMID:18299575, GO:0045724=GO_REF:0000024, GO:0000226=GO_REF:0000024, GO:0031513=PMID:17574030, GO:0046907=GO_REF:0000024, GO:0035058=GO_REF:0000024, GO:0003777=PMID:15107855, GO:0048854=GO_REF:0000024, GO:0060296=GO_REF:0000024, GO:0051297=PMID:15107855, GO:0021756=GO_REF:0000024, GO:0021766=GO_REF:0000024, GO:0042384=GO_REF:0000024, GO:0050893=PMID:14520415, GO:0010629=GO_REF:0000019, GO:0034454=PMID:15107855} Q96RK4 Bardet-Biedl syndrome 4 protein protein 20111111 {GO:0005515=IPI, GO:0007608=ISS, GO:0034452=IDA, GO:0034451=IDA, GO:0007286=ISS, GO:0045494=ISS, GO:0032402=ISS, GO:0051877=ISS, GO:0001947=ISS, GO:0001895=ISS, GO:0045444=ISS, GO:0030534=ISS, GO:0005932=IDA, GO:0003085=IEA, GO:0000242=IDA, GO:0005813=IDA, GO:0032465=IMP, GO:0005814=IDA, GO:0046548=ISS, GO:0048487=IDA, GO:0001843=ISS, GO:0016358=ISS, GO:0019216=ISS, GO:0051457=IGI, GO:0060271=ISS, GO:0038108=ISS, GO:0060170=IDA, GO:0021987=ISS, GO:0005737=IDA, GO:0060027=ISS, GO:0040018=IEA, GO:0034464=IDA, GO:0033365=ISS, GO:0043014=IDA, GO:0031514=IDA, GO:0045724=ISS, GO:0000226=ISS, GO:0031513=IDA, GO:0046907=ISS, GO:0035058=ISS, GO:0003777=IMP, GO:0048854=ISS, GO:0060296=ISS, GO:0051297=IMP, GO:0021756=ISS, GO:0021766=ISS, GO:0042384=ISS, GO:0050893=TAS, GO:0010629=IEA, GO:0034454=IMP} adult behavior, brain morphogenesis, centrosome organization, cerebral cortex development, cilium assembly, cilium morphogenesis, convergent extension involved in gastrulation, dendrite development, fat cell differentiation, heart looping, hippocampus development, intracellular transport, maintenance of protein location in nucleus, melanosome transport, microtubule anchoring at centrosome, microtubule cytoskeleton organization, negative regulation of appetite by leptin-mediated signaling pathway, negative regulation of gene expression, negative regulation of systemic arterial blood pressure, neural tube closure, nonmotile primary cilium assembly, photoreceptor cell maintenance, pigment granule aggregation in cell center, positive regulation of cilium assembly, positive regulation of multicellular organism growth, protein localization to organelle, regulation of cilium beat frequency involved in ciliary motility, regulation of cytokinesis, regulation of lipid metabolic process, retina homeostasis, retinal rod cell development, sensory perception of smell, sensory processing, spermatid development, striatum development BBSome, centriolar satellite, centriole, centrosome, cilium membrane, cytoplasm, microtubule basal body, motile cilium, nonmotile primary cilium, pericentriolar material alpha-tubulin binding, beta-tubulin binding, dynactin binding, microtubule motor activity, protein binding Human BBS5 BHF-UCL UniProtKB {GO:0005515=PMID:20080638, GO:0060170=GO_REF:0000039, GO:0034464=PMID:17574030, GO:0032266=PMID:17574030, GO:0032402=GO_REF:0000024, GO:0005622=GO_REF:0000054, GO:0001947=GO_REF:0000024, GO:0042384=PMID:17574030, GO:0005737=GO_REF:0000039, GO:0009296=GO_REF:0000024, GO:0005932=GO_REF:0000024, GO:0007601=GO_REF:0000037, GO:0050896=GO_REF:0000037} Q8N3I7 Bardet-Biedl syndrome 5 protein protein 20080812 {GO:0005515=IPI, GO:0060170=IEA, GO:0034464=IDA, GO:0032266=IDA, GO:0032402=ISS, GO:0005622=IDA, GO:0001947=ISS, GO:0042384=IMP, GO:0005737=IEA, GO:0009296=ISS, GO:0005932=ISS, GO:0007601=IEA, GO:0050896=IEA} cilium assembly, flagellum assembly, heart looping, melanosome transport, response to stimulus, visual perception BBSome, cilium membrane, cytoplasm, intracellular, microtubule basal body phosphatidylinositol-3-phosphate binding, protein binding Human UniProtKB:Q7ZWB7 BBS7 BHF-UCL UniProtKB {GO:0005515=PMID:18000879, GO:0034464=PMID:17574030, GO:0060170=GO_REF:0000039, GO:0005813=PMID:21399614, GO:0007368=GO_REF:0000024, GO:0048546=GO_REF:0000024, GO:0051877=GO_REF:0000024, GO:0032402=GO_REF:0000024, GO:0001947=GO_REF:0000024, GO:0005737=GO_REF:0000039, GO:0060271=GO_REF:0000024, GO:0045444=GO_REF:0000024, GO:0007601=GO_REF:0000037, GO:0050896=GO_REF:0000037} Q8IWZ6 Bardet-Biedl syndrome 7 protein protein 20080812 {GO:0005515=IPI, GO:0034464=IDA, GO:0060170=IEA, GO:0005813=IDA, GO:0007368=ISS, GO:0048546=ISS, GO:0051877=ISS, GO:0032402=ISS, GO:0001947=ISS, GO:0005737=IEA, GO:0060271=ISS, GO:0045444=ISS, GO:0007601=IEA, GO:0050896=IEA} cilium morphogenesis, determination of left/right symmetry, digestive tract morphogenesis, fat cell differentiation, heart looping, melanosome transport, pigment granule aggregation in cell center, response to stimulus, visual perception BBSome, centrosome, cilium membrane, cytoplasm protein binding Human UniProtKB:Q08C18 BBS9 HPA UniProtKB {GO:0005515=PMID:22500027, GO:0003674=GO_REF:0000015, GO:0060170=GO_REF:0000039, GO:0005737=GO_REF:0000052, GO:0034464=PMID:17574030, GO:0005815=GO_REF:0000039, GO:0005886=GO_REF:0000052, GO:0005730=GO_REF:0000052, GO:0045444=GO_REF:0000024, GO:0005634=GO_REF:0000052, GO:0007601=GO_REF:0000037, GO:0050896=GO_REF:0000037} Q3SYG4 Protein PTHB1 protein 20101115 {GO:0005515=IPI, GO:0003674=ND, GO:0060170=IEA, GO:0005737=IDA, GO:0034464=IDA, GO:0005815=IEA, GO:0005886=IDA, GO:0005730=IDA, GO:0045444=ISS, GO:0005634=IDA, GO:0007601=IEA, GO:0050896=IEA} fat cell differentiation, response to stimulus, visual perception BBSome, cilium membrane, cytoplasm, microtubule organizing center, nucleolus, nucleus, plasma membrane molecular_function, protein binding Human BBX UniProtKB UniProtKB {GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q8WY36 HMG box transcription factor BBX protein 20130413 {GO:0006355=IEA, GO:0005634=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus DNA binding Human UniProtKB-SubCell:SL-0191 BCAM BHF-UCL UniProtKB {GO:0007165=PMID:7777537, GO:0007160=PMID:16236823, GO:0005886=PMID:9166867, GO:0009986=PMID:12493773, GO:0016020=GO_REF:0000038, GO:0005887=PMID:7777537, GO:0043236=PMID:16236823, GO:0005055=PMID:16236823, GO:0007155=PMID:7954395, GO:0009897=PMID:16236823, GO:0004888=PMID:7777537} P50895 Basal cell adhesion molecule protein 20090408 {GO:0007165=TAS, GO:0007160=IMP, GO:0005886=TAS, GO:0009986=IDA, GO:0016020=IEA, GO:0005887=TAS, GO:0043236=IMP, GO:0005055=IMP, GO:0007155=TAS, GO:0009897=IC, GO:0004888=TAS} cell adhesion, cell-matrix adhesion, signal transduction cell surface, external side of plasma membrane, integral to plasma membrane, membrane, plasma membrane laminin binding, laminin receptor activity, transmembrane signaling receptor activity Human BCAN Reactome UniProtKB {GO:0005796=Reactome:REACT_121341, GO:0005975=Reactome:REACT_474, GO:0005578=GO_REF:0000039, GO:0005576=Reactome:REACT_121341, GO:0044281=Reactome:REACT_111217, GO:0031225=GO_REF:0000037, GO:0030208=Reactome:REACT_120800, GO:0021766=GO_REF:0000019, GO:0030207=Reactome:REACT_120888, GO:0030206=Reactome:REACT_120989, GO:0005540=GO_REF:0000037, GO:0030246=GO_REF:0000002, GO:0007155=GO_REF:0000002, GO:0030204=Reactome:REACT_121206, GO:0030203=Reactome:REACT_121408, GO:0043202=Reactome:REACT_121272} Q96GW7 Brevican core protein protein 20130301 {GO:0005796=TAS, GO:0005975=TAS, GO:0005578=IEA, GO:0005576=TAS, GO:0044281=TAS, GO:0031225=IEA, GO:0030208=TAS, GO:0021766=IEA, GO:0030207=TAS, GO:0030206=TAS, GO:0005540=IEA, GO:0030246=IEA, GO:0007155=IEA, GO:0030204=TAS, GO:0030203=TAS, GO:0043202=TAS} carbohydrate metabolic process, cell adhesion, chondroitin sulfate biosynthetic process, chondroitin sulfate catabolic process, chondroitin sulfate metabolic process, dermatan sulfate biosynthetic process, glycosaminoglycan metabolic process, hippocampus development, small molecule metabolic process Golgi lumen, anchored to membrane, extracellular region, lysosomal lumen, proteinaceous extracellular matrix carbohydrate binding, hyaluronic acid binding Human BCAP29 UniProtKB UniProtKB {GO:0005783=GO_REF:0000002, GO:0005789=GO_REF:0000039, GO:0006915=GO_REF:0000037, GO:0016021=GO_REF:0000037, GO:0016192=GO_REF:0000037, GO:0006886=GO_REF:0000002} Q9UHQ4 B-cell receptor-associated protein 29 protein 20130413 {GO:0005783=IEA, GO:0005789=IEA, GO:0006915=IEA, GO:0016021=IEA, GO:0016192=IEA, GO:0006886=IEA} apoptotic process, intracellular protein transport, vesicle-mediated transport endoplasmic reticulum, endoplasmic reticulum membrane, integral to membrane Human UniProtKB-SubCell:SL-0097 BCAP31 HPA UniProtKB {GO:0005515=PMID:21183955, GO:0002474=Reactome:REACT_75820, GO:0035584=PMID:21183955, GO:0005886=GO_REF:0000019, GO:0005783=GO_REF:0000052, GO:0005102=GO_REF:0000029, GO:0006915=Reactome:REACT_578, GO:0007283=GO_REF:0000019, GO:0006886=GO_REF:0000002, GO:0007204=PMID:21183955, GO:0006921=Reactome:REACT_995, GO:0005829=Reactome:REACT_13554, GO:0043280=PMID:21183955, GO:0006955=GO_REF:0000029, GO:0000139=GO_REF:0000019, GO:0051561=PMID:21183955, GO:0005887=PMID:8706661, GO:0033116=GO_REF:0000039, GO:0005789=Reactome:REACT_13554, GO:0071556=Reactome:REACT_75922, GO:0016021=GO_REF:0000002, GO:0016192=GO_REF:0000037, GO:0032471=PMID:21183955} P51572 B-cell receptor-associated protein 31 protein 20080205 {GO:0005515=IPI, GO:0002474=TAS, GO:0035584=IMP, GO:0005886=IEA, GO:0005783=IDA, GO:0005102=NAS, GO:0006915=TAS, GO:0007283=IEA, GO:0006886=IEA, GO:0007204=IMP, GO:0006921=TAS, GO:0005829=TAS, GO:0043280=IMP, GO:0006955=NAS, GO:0000139=IEA, GO:0051561=IMP, GO:0005887=IDA, GO:0033116=IEA, GO:0005789=TAS, GO:0071556=TAS, GO:0016021=IEA, GO:0016192=IEA, GO:0032471=IMP} antigen processing and presentation of peptide antigen via MHC class I, apoptotic process, calcium-mediated signaling using intracellular calcium source, cellular component disassembly involved in execution phase of apoptosis, elevation of cytosolic calcium ion concentration, elevation of mitochondrial calcium ion concentration, immune response, intracellular protein transport, positive regulation of cysteine-type endopeptidase activity involved in apoptotic process, reduction of endoplasmic reticulum calcium ion concentration, spermatogenesis, vesicle-mediated transport Golgi membrane, cytosol, endoplasmic reticulum, endoplasmic reticulum membrane, endoplasmic reticulum-Golgi intermediate compartment membrane, integral to lumenal side of endoplasmic reticulum membrane, integral to membrane, integral to plasma membrane, plasma membrane protein binding, receptor binding Human BCAR1 BHF-UCL UniProtKB {GO:0008286=GO_REF:0000024, GO:0005515=PMID:19732724, GO:0050853=PMID:9020138, GO:0050852=PMID:9295052, GO:0017124=GO_REF:0000037, GO:0005886=PMID:21245381, GO:0008283=PMID:10639512, GO:0001558=PMID:11607844, GO:0050851=PMID:10587647, GO:0005829=Reactome:REACT_16951, GO:0005737=PMID:8070403, GO:0007173=GO_REF:0000024, GO:0035729=PMID:21245381, GO:0007015=PMID:16105984, GO:0004871=PMID:8070403, GO:0007155=GO_REF:0000037, GO:0048010=PMID:21245381, GO:0048011=GO_REF:0000024, GO:0048012=PMID:21245381, GO:0030335=PMID:9472046, GO:0019901=PMID:9020138, GO:0030168=Reactome:REACT_798, GO:0042981=PMID:11607844, GO:0001726=PMID:9472046, GO:0030027=GO_REF:0000019, GO:0010595=PMID:21245381, GO:0007186=PMID:10092204, GO:0016477=PMID:9425168, GO:0060326=PMID:21245381, GO:0007596=Reactome:REACT_604, GO:0007229=PMID:8649368, GO:0048008=GO_REF:0000024, GO:0005925=PMID:21245381, GO:0051301=PMID:10675905} P56945 Breast cancer anti-estrogen resistance protein 1 protein 20121127 {GO:0008286=ISS, GO:0005515=IPI, GO:0050853=IDA, GO:0050852=NAS, GO:0017124=IEA, GO:0005886=IDA, GO:0008283=TAS, GO:0001558=TAS, GO:0050851=IDA, GO:0005829=TAS, GO:0005737=IDA, GO:0007173=ISS, GO:0035729=IMP, GO:0007015=IDA, GO:0004871=TAS, GO:0007155=IEA, GO:0048010=IMP, GO:0048011=ISS, GO:0048012=IMP, GO:0030335=IDA, GO:0019901=IPI, GO:0030168=TAS, GO:0042981=TAS, GO:0001726=IDA, GO:0030027=IEA, GO:0010595=IDA, GO:0007186=NAS, GO:0016477=IDA, GO:0060326=IMP, GO:0007596=TAS, GO:0007229=IDA, GO:0048008=ISS, GO:0005925=IDA, GO:0051301=NAS} B cell receptor signaling pathway, G-protein coupled receptor signaling pathway, T cell receptor signaling pathway, actin filament organization, antigen receptor-mediated signaling pathway, blood coagulation, cell adhesion, cell chemotaxis, cell division, cell migration, cell proliferation, cellular response to hepatocyte growth factor stimulus, epidermal growth factor receptor signaling pathway, hepatocyte growth factor receptor signaling pathway, insulin receptor signaling pathway, integrin-mediated signaling pathway, neurotrophin TRK receptor signaling pathway, platelet activation, platelet-derived growth factor receptor signaling pathway, positive regulation of cell migration, positive regulation of endothelial cell migration, regulation of apoptotic process, regulation of cell growth, vascular endothelial growth factor receptor signaling pathway cytoplasm, cytosol, focal adhesion, lamellipodium, plasma membrane, ruffle SH3 domain binding, protein binding, protein kinase binding, signal transducer activity Human BCAR3 InterPro UniProtKB {GO:0005085=GO_REF:0000002, GO:0005622=GO_REF:0000002, GO:0007165=PMID:9582273, GO:0007264=GO_REF:0000002, GO:0042493=PMID:9582273} Q5TEW3 Breast cancer anti-estrogen resistance protein 3 protein 20130413 {GO:0005085=IEA, GO:0005622=IEA, GO:0007165=TAS, GO:0007264=IEA, GO:0042493=TAS} response to drug, signal transduction, small GTPase mediated signal transduction intracellular guanyl-nucleotide exchange factor activity Human InterPro:IPR001895 BCAS1 UniProtKB UniProtKB {GO:0005737=GO_REF:0000039} O75363 Breast carcinoma-amplified sequence 1 protein 20130413 {GO:0005737=IEA} cytoplasm Human UniProtKB-SubCell:SL-0086 BCAS2 MGI UniProtKB {GO:0005515=PMID:20176811, GO:0008380=PMID:9731529, GO:0006397=GO_REF:0000037, GO:0000375=PMID:9731529, GO:0005730=GO_REF:0000039, GO:0005681=PMID:12169396} O75934 Pre-mRNA-splicing factor SPF27 protein 20060110 {GO:0005515=IPI, GO:0008380=TAS, GO:0006397=IEA, GO:0000375=TAS, GO:0005730=IEA, GO:0005681=IDA} RNA splicing, RNA splicing, via transesterification reactions, mRNA processing nucleolus, spliceosomal complex protein binding Human BCAS3 IntAct UniProtKB {GO:0005515=PMID:22300583, GO:0005737=GO_REF:0000019, GO:0005634=GO_REF:0000039, GO:0071944=GO_REF:0000019} Q9H6U6 Breast carcinoma-amplified sequence 3 protein 20130415 {GO:0005515=IPI, GO:0005737=IEA, GO:0005634=IEA, GO:0071944=IEA} cell periphery, cytoplasm, nucleus protein binding Human UniProtKB:P08670 BCAS4 UniProtKB UniProtKB {GO:0005737=GO_REF:0000039} Q8TDM0 Breast carcinoma-amplified sequence 4 protein 20130413 {GO:0005737=IEA} cytoplasm Human UniProtKB-SubCell:SL-0086 BCAT1 Reactome UniProtKB {GO:0034641=Reactome:REACT_13, GO:0000082=PMID:8692959, GO:0009082=GO_REF:0000037, GO:0008283=PMID:6933702, GO:0004084=Reactome:REACT_21283, GO:0052656=GO_REF:0000003, GO:0052654=GO_REF:0000003, GO:0052655=GO_REF:0000003, GO:0009083=Reactome:REACT_197, GO:0044281=Reactome:REACT_111217, GO:0003824=GO_REF:0000002, GO:0005829=Reactome:REACT_21283} P54687 Branched-chain-amino-acid aminotransferase, cytosolic protein 20130213 {GO:0034641=TAS, GO:0000082=TAS, GO:0009082=IEA, GO:0008283=TAS, GO:0004084=EXP, GO:0052656=IEA, GO:0052654=IEA, GO:0052655=IEA, GO:0009083=TAS, GO:0044281=TAS, GO:0003824=IEA, GO:0005829=TAS} G1/S transition of mitotic cell cycle, branched-chain amino acid biosynthetic process, branched-chain amino acid catabolic process, cell proliferation, cellular nitrogen compound metabolic process, small molecule metabolic process cytosol L-isoleucine transaminase activity, L-leucine transaminase activity, L-valine transaminase activity, branched-chain-amino-acid transaminase activity, catalytic activity Human BCAT2 Reactome UniProtKB {GO:0052656=GO_REF:0000003, GO:0004084=Reactome:REACT_21409, GO:0052654=GO_REF:0000003, GO:0052655=GO_REF:0000003, GO:0009083=Reactome:REACT_197, GO:0044281=Reactome:REACT_111217, GO:0003824=GO_REF:0000002, GO:0010817=GO_REF:0000019, GO:0005739=PMID:9165094, GO:0034641=Reactome:REACT_13, GO:0009082=GO_REF:0000037, GO:0009081=GO_REF:0000002, GO:0005759=Reactome:REACT_21409, GO:0006573=GO_REF:0000019, GO:0006551=GO_REF:0000019, GO:0006550=GO_REF:0000019} O15382 Branched-chain-amino-acid aminotransferase, mitochondrial protein 20130213 {GO:0052656=IEA, GO:0004084=EXP, GO:0052654=IEA, GO:0052655=IEA, GO:0009083=TAS, GO:0044281=TAS, GO:0003824=IEA, GO:0010817=IEA, GO:0005739=TAS, GO:0034641=TAS, GO:0009082=IEA, GO:0009081=IEA, GO:0005759=TAS, GO:0006573=IEA, GO:0006551=IEA, GO:0006550=IEA} branched-chain amino acid biosynthetic process, branched-chain amino acid catabolic process, branched-chain amino acid metabolic process, cellular nitrogen compound metabolic process, isoleucine catabolic process, leucine metabolic process, regulation of hormone levels, small molecule metabolic process, valine metabolic process mitochondrial matrix, mitochondrion L-isoleucine transaminase activity, L-leucine transaminase activity, L-valine transaminase activity, branched-chain-amino-acid transaminase activity, catalytic activity Human BCCIP MGI UniProtKB {GO:0005515=PMID:18440304, GO:0007049=GO_REF:0000037, GO:0019908=PMID:10878006, GO:0006281=GO_REF:0000037, GO:0005634=PMID:10878006, GO:0061101=PMID:18440304, GO:0000079=PMID:10878006, GO:0019207=PMID:10878006} Q9P287 BRCA2 and CDKN1A-interacting protein protein 20091019 {GO:0005515=IPI, GO:0007049=IEA, GO:0019908=IDA, GO:0006281=IEA, GO:0005634=TAS, GO:0061101=IDA, GO:0000079=IDA, GO:0019207=IDA} DNA repair, cell cycle, neuroendocrine cell differentiation, regulation of cyclin-dependent protein serine/threonine kinase activity nuclear cyclin-dependent protein kinase holoenzyme complex, nucleus kinase regulator activity, protein binding Human BCDIN3D UniProtKB UniProtKB {GO:0001510=PMID:23063121, GO:0005737=PMID:23063121, GO:2000632=PMID:23063121, GO:0008171=PMID:23063121, GO:0008173=PMID:23063121, GO:0010586=PMID:23063121} Q7Z5W3 Pre-miRNA 5'-monophosphate methyltransferase protein 20121022 {GO:0001510=IDA, GO:0005737=IDA, GO:2000632=IDA, GO:0008171=IDA, GO:0008173=IDA, GO:0010586=IDA} RNA methylation, miRNA metabolic process, negative regulation of pre-miRNA processing cytoplasm O-methyltransferase activity, RNA methyltransferase activity Human BCHE ENSEMBL UniProtKB {GO:0004091=GO_REF:0000002, GO:0003990=GO_REF:0000024, GO:0005783=GO_REF:0000019, GO:0004104=PMID:19452557, GO:0005576=Reactome:REACT_19294, GO:0003824=PMID:11569538, GO:0005615=GO_REF:0000033, GO:0019695=GO_REF:0000033, GO:0007271=GO_REF:0000033, GO:0001540=PMID:11569538, GO:0016020=GO_REF:0000002, GO:0005641=GO_REF:0000019, GO:0050783=PMID:8622553, GO:0005788=GO_REF:0000033, GO:0019899=PMID:11569538, GO:0044267=Reactome:REACT_17015} Q96HL2 Cholinesterase protein 20130413 {GO:0004091=IEA, GO:0003990=ISS, GO:0005783=IEA, GO:0004104=IDA, GO:0005576=TAS, GO:0003824=NAS, GO:0005615=IBA, GO:0019695=IBA, GO:0007271=IBA, GO:0001540=NAS, GO:0016020=IEA, GO:0005641=IEA, GO:0050783=TAS, GO:0005788=IBA, GO:0019899=NAS, GO:0044267=TAS} cellular protein metabolic process, choline metabolic process, cocaine metabolic process, synaptic transmission, cholinergic endoplasmic reticulum, endoplasmic reticulum lumen, extracellular region, extracellular space, membrane, nuclear envelope lumen acetylcholinesterase activity, beta-amyloid binding, carboxylesterase activity, catalytic activity, cholinesterase activity, enzyme binding Human Ensembl:ENSMUSP00000029367 BCKDHA IntAct UniProtKB {GO:0005515=PMID:15576032, GO:0005739=PMID:11839747, GO:0003863=GO_REF:0000003, GO:0034641=Reactome:REACT_13, GO:0005759=Reactome:REACT_1813, GO:0016831=PMID:11839747, GO:0016624=GO_REF:0000002, GO:0005947=PMID:7883996, GO:0009083=Reactome:REACT_197, GO:0044281=Reactome:REACT_111217, GO:0003826=PMID:7883996, GO:0046872=GO_REF:0000037} P12694 2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial protein 20130415 {GO:0005515=IPI, GO:0005739=TAS, GO:0003863=IEA, GO:0034641=TAS, GO:0005759=TAS, GO:0016831=TAS, GO:0016624=IEA, GO:0005947=IDA, GO:0009083=TAS, GO:0044281=TAS, GO:0003826=IDA, GO:0046872=IEA} branched-chain amino acid catabolic process, cellular nitrogen compound metabolic process, small molecule metabolic process mitochondrial alpha-ketoglutarate dehydrogenase complex, mitochondrial matrix, mitochondrion 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity, alpha-ketoacid dehydrogenase activity, carboxy-lyase activity, metal ion binding, oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor, protein binding Human UniProtKB:P21953 BCKDHB IntAct UniProtKB {GO:0005515=PMID:15576032, GO:0003863=GO_REF:0000003, GO:0007584=GO_REF:0000019, GO:0051384=GO_REF:0000019, GO:0009083=Reactome:REACT_197, GO:0044281=Reactome:REACT_111217, GO:0032403=GO_REF:0000019, GO:0051591=GO_REF:0000019, GO:0003826=GO_REF:0000019, GO:0005739=PMID:2022752, GO:0034641=Reactome:REACT_13, GO:0005759=Reactome:REACT_1813, GO:0016831=PMID:11839747, GO:0005947=PMID:2022752} P21953 2-oxoisovalerate dehydrogenase subunit beta, mitochondrial protein 20130415 {GO:0005515=IPI, GO:0003863=IEA, GO:0007584=IEA, GO:0051384=IEA, GO:0009083=TAS, GO:0044281=TAS, GO:0032403=IEA, GO:0051591=IEA, GO:0003826=IEA, GO:0005739=IMP, GO:0034641=TAS, GO:0005759=TAS, GO:0016831=TAS, GO:0005947=IMP} branched-chain amino acid catabolic process, cellular nitrogen compound metabolic process, response to cAMP, response to glucocorticoid stimulus, response to nutrient, small molecule metabolic process mitochondrial alpha-ketoglutarate dehydrogenase complex, mitochondrial matrix, mitochondrion 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity, alpha-ketoacid dehydrogenase activity, carboxy-lyase activity, protein binding, protein complex binding Human UniProtKB:P12694 BCKDK UniProtKB UniProtKB {GO:0005515=PMID:21988832, GO:0005739=PMID:11839747, GO:0016310=GO_REF:0000024, GO:0016301=GO_REF:0000038, GO:0004674=GO_REF:0000024, GO:0047323=GO_REF:0000003, GO:0005947=GO_REF:0000024, GO:0009083=GO_REF:0000024, GO:0009063=PMID:2403034, GO:0005524=GO_REF:0000002} Q96G95 BCKDK protein protein 20130413 {GO:0005515=IPI, GO:0005739=TAS, GO:0016310=ISS, GO:0016301=IEA, GO:0004674=ISS, GO:0047323=IEA, GO:0005947=ISS, GO:0009083=ISS, GO:0009063=NAS, GO:0005524=IEA} branched-chain amino acid catabolic process, cellular amino acid catabolic process, phosphorylation mitochondrial alpha-ketoglutarate dehydrogenase complex, mitochondrion "ATP binding, 3-methyl-2-oxobutanoate dehydrogenase (acetyl-transferring)"" kinase activity, kinase activity, protein binding, protein serine/threonine kinase activity""" Human UniProtKB-KW:KW-0418 BCL10 BHF-UCL UniProtKB {GO:0005515=PMID:16280327, GO:0008219=PMID:10400625, GO:0043130=PMID:15082780, GO:0016064=GO_REF:0000019, GO:0042226=PMID:16647297, GO:0002020=PMID:18223652, GO:0043621=PMID:15125833, GO:0005764=PMID:15082780, GO:0042221=PMID:17095757, GO:0051259=PMID:14695475, GO:0002906=PMID:15878976, GO:0031398=PMID:14695475, GO:0051260=PMID:16831874, GO:0043123=PMID:12761501, GO:0031625=PMID:16395405, GO:0046696=PMID:16831874, GO:0032765=PMID:16647297, GO:0019901=PMID:17052756, GO:0003713=PMID:15207693, GO:0045416=PMID:17095757, GO:0001843=PMID:11163238, GO:0002224=PMID:16831874, GO:0043234=PMID:14695475, GO:0019209=PMID:15125833, GO:0045087=PMID:16831874, GO:0050870=GO_REF:0000019, GO:0045121=GO_REF:0000039, GO:0045893=PMID:15207693, GO:0019899=PMID:14695475, GO:0008134=PMID:15207693, GO:0005881=PMID:23264731, GO:0050852=Reactome:REACT_12526, GO:0048471=PMID:16127295, GO:0005886=Reactome:REACT_118777, GO:0050856=GO_REF:0000019, GO:0002237=PMID:16831874, GO:0009620=GO_REF:0000019, GO:0005634=PMID:16280327, GO:0005829=Reactome:REACT_118777, GO:0005737=PMID:15082780, GO:0051092=PMID:14695475, GO:0042101=PMID:12154360, GO:0019900=PMID:17052756, GO:0042109=PMID:16647297, GO:0001772=GO_REF:0000019, GO:0051059=PMID:16280327, GO:0032449=PMID:15125833, GO:0006915=PMID:11466612, GO:0008022=PMID:11053425, GO:0043422=PMID:16280327, GO:0002250=PMID:16831874, GO:0006968=GO_REF:0000019, GO:0071260=PMID:19593445, GO:0042327=PMID:15125833} O95999 B-cell lymphoma/leukemia 10 protein 20110201 {GO:0005515=IPI, GO:0008219=IDA, GO:0043130=IDA, GO:0016064=IEA, GO:0042226=NAS, GO:0002020=IPI, GO:0043621=IPI, GO:0005764=IDA, GO:0042221=IDA, GO:0051259=IPI, GO:0002906=IDA, GO:0031398=IDA, GO:0051260=TAS, GO:0043123=IEP, GO:0031625=IPI, GO:0046696=IDA, GO:0032765=NAS, GO:0019901=IDA, GO:0003713=IDA, GO:0045416=IMP, GO:0001843=ISS, GO:0002224=IC, GO:0043234=IDA, GO:0019209=IDA, GO:0045087=IEP, GO:0050870=IEA, GO:0045121=IEA, GO:0045893=IDA, GO:0019899=IPI, GO:0008134=IPI, GO:0005881=IDA, GO:0050852=TAS, GO:0048471=IDA, GO:0005886=TAS, GO:0050856=IEA, GO:0002237=IEP, GO:0009620=IEA, GO:0005634=IDA, GO:0005829=TAS, GO:0005737=IDA, GO:0051092=IDA, GO:0042101=IDA, GO:0019900=IPI, GO:0042109=NAS, GO:0001772=IEA, GO:0051059=IDA, GO:0032449=NAS, GO:0006915=IDA, GO:0008022=IPI, GO:0043422=IPI, GO:0002250=TAS, GO:0006968=IEA, GO:0071260=IEP, GO:0042327=IDA} T cell receptor signaling pathway, adaptive immune response, apoptotic process, cell death, cellular defense response, cellular response to mechanical stimulus, immunoglobulin mediated immune response, innate immune response, interleukin-6 biosynthetic process, lymphotoxin A biosynthetic process, negative regulation of mature B cell apoptotic process, neural tube closure, positive regulation of I-kappaB kinase/NF-kappaB cascade, positive regulation of NF-kappaB transcription factor activity, positive regulation of T cell activation, positive regulation of interleukin-8 biosynthetic process, positive regulation of mast cell cytokine production, positive regulation of phosphorylation, positive regulation of protein ubiquitination, positive regulation of transcription, DNA-dependent, protein homooligomerization, protein oligomerization, regulation of T cell receptor signaling pathway, response to chemical stimulus, response to fungus, response to molecule of bacterial origin, toll-like receptor signaling pathway CBM complex, T cell receptor complex, cytoplasm, cytoplasmic microtubule, cytosol, immunological synapse, lipopolysaccharide receptor complex, lysosome, membrane raft, nucleus, perinuclear region of cytoplasm, plasma membrane, protein complex NF-kappaB binding, enzyme binding, kinase activator activity, kinase binding, protease binding, protein C-terminus binding, protein binding, protein kinase B binding, protein kinase binding, protein self-association, transcription coactivator activity, transcription factor binding, ubiquitin binding, ubiquitin protein ligase binding Human UniProtKB:Q9UDY8 BCL11A UniProtKB UniProtKB {GO:0030097=GO_REF:0000029, GO:0005737=GO_REF:0000029, GO:0006355=GO_REF:0000037, GO:0030217=GO_REF:0000019, GO:0016925=GO_REF:0000024, GO:0003714=GO_REF:0000019, GO:0030183=GO_REF:0000019, GO:0010629=GO_REF:0000019, GO:0005634=GO_REF:0000029, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0006351=GO_REF:0000037} Q9H165 B-cell lymphoma/leukemia 11A protein 20100802 {GO:0030097=NAS, GO:0005737=NAS, GO:0006355=IEA, GO:0030217=IEA, GO:0016925=ISS, GO:0003714=IEA, GO:0030183=IEA, GO:0010629=IEA, GO:0005634=NAS, GO:0008270=IEA, GO:0003676=IEA, GO:0006351=IEA} B cell differentiation, T cell differentiation, hemopoiesis, negative regulation of gene expression, protein sumoylation, regulation of transcription, DNA-dependent, transcription, DNA-dependent cytoplasm, nucleus nucleic acid binding, transcription corepressor activity, zinc ion binding Human UniProtKB:Q9QYE3 BCL11B MGI UniProtKB {GO:0071678=GO_REF:0000019, GO:0003382=GO_REF:0000019, GO:0043066=GO_REF:0000019, GO:0033077=GO_REF:0000019, GO:0008285=GO_REF:0000019, GO:0033153=GO_REF:0000019, GO:0046632=GO_REF:0000019, GO:0010837=GO_REF:0000019, GO:0005634=GO_REF:0000039, GO:0048538=GO_REF:0000019, GO:0003676=GO_REF:0000002, GO:0000978=GO_REF:0000019, GO:0003334=GO_REF:0000019, GO:0043368=GO_REF:0000019, GO:0031077=GO_REF:0000019, GO:0019216=GO_REF:0000019, GO:0001077=GO_REF:0000019, GO:0045944=PMID:16809611, GO:0045664=GO_REF:0000019, GO:0021773=GO_REF:0000019, GO:0042475=GO_REF:0000019, GO:0043588=GO_REF:0000019, GO:0008270=GO_REF:0000002} Q9C0K0 B-cell lymphoma/leukemia 11B protein 20101118 {GO:0071678=IEA, GO:0003382=IEA, GO:0043066=IEA, GO:0033077=IEA, GO:0008285=IEA, GO:0033153=IEA, GO:0046632=IEA, GO:0010837=IEA, GO:0005634=IEA, GO:0048538=IEA, GO:0003676=IEA, GO:0000978=IEA, GO:0003334=IEA, GO:0043368=IEA, GO:0031077=IEA, GO:0019216=IEA, GO:0001077=IEA, GO:0045944=IMP, GO:0045664=IEA, GO:0021773=IEA, GO:0042475=IEA, GO:0043588=IEA, GO:0008270=IEA} T cell differentiation in thymus, T cell receptor V(D)J recombination, alpha-beta T cell differentiation, epithelial cell morphogenesis, keratinocyte development, negative regulation of apoptotic process, negative regulation of cell proliferation, odontogenesis of dentin-containing tooth, olfactory bulb axon guidance, positive T cell selection, positive regulation of transcription from RNA polymerase II promoter, post-embryonic camera-type eye development, regulation of keratinocyte proliferation, regulation of lipid metabolic process, regulation of neuron differentiation, skin development, striatal medium spiny neuron differentiation, thymus development nucleus RNA polymerase II core promoter proximal region sequence-specific DNA binding, RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription, nucleic acid binding, zinc ion binding Human BCL2 BHF-UCL UniProtKB {GO:0005515=PMID:21454712, GO:0030308=GO_REF:0000019, GO:0030307=PMID:8022822, GO:0010523=GO_REF:0000019, GO:0045069=GO_REF:0000019, GO:0051402=PMID:16167175, GO:0009791=GO_REF:0000019, GO:0048599=GO_REF:0000019, GO:0031069=GO_REF:0000019, GO:0016337=GO_REF:0000019, GO:0051607=PMID:10620603, GO:1900740=Reactome:REACT_697, GO:0048589=GO_REF:0000019, GO:0018105=GO_REF:0000019, GO:0018107=GO_REF:0000019, GO:0014031=GO_REF:0000019, GO:0002326=GO_REF:0000019, GO:0033033=GO_REF:0000019, GO:0010332=GO_REF:0000019, GO:0031625=PMID:20889974, GO:0000209=PMID:16717086, GO:0002320=GO_REF:0000019, GO:0046982=PMID:9111042, GO:0071310=GO_REF:0000019, GO:0032469=GO_REF:0000019, GO:0009636=PMID:16307838, GO:2001244=Reactome:REACT_330, GO:0043085=GO_REF:0000019, GO:0001503=GO_REF:0000019, GO:0070059=PMID:15776018, GO:0045087=Reactome:REACT_6802, GO:0005789=GO_REF:0000039, GO:0016049=GO_REF:0000019, GO:0008134=GO_REF:0000019, GO:0050853=PMID:17875758, GO:0001782=GO_REF:0000019, GO:0005783=PMID:8402648, GO:0030890=PMID:17875758, GO:0005634=PMID:7896880, GO:0001836=PMID:9843949, GO:0005829=GO_REF:0000019, GO:0033138=GO_REF:0000019, GO:0048873=GO_REF:0000019, GO:0042100=PMID:1373874, GO:0051902=PMID:9027314, GO:0043209=GO_REF:0000019, GO:0006959=PMID:1908951, GO:0001101=GO_REF:0000019, GO:0007015=GO_REF:0000019, GO:0040018=GO_REF:0000019, GO:0051721=GO_REF:0000019, GO:0009314=PMID:15799693, GO:0046902=PMID:9843949, GO:0051434=PMID:9111042, GO:0042493=PMID:36599, GO:0046671=GO_REF:0000019, GO:0072593=GO_REF:0000019, GO:0006974=PMID:17875758, GO:0009605=GO_REF:0000019, GO:0016020=PMID:7896880, GO:0010224=GO_REF:0000019, GO:0015267=PMID:9219694, GO:0035094=PMID:12421819, GO:0001656=GO_REF:0000019, GO:0043496=PMID:9111042, GO:0008219=PMID:8022822, GO:0042542=GO_REF:0000019, GO:0043497=PMID:9111042, GO:0001658=GO_REF:0000019, GO:0033689=GO_REF:0000019, GO:0048538=GO_REF:0000019, GO:0048753=GO_REF:0000019, GO:0048536=GO_REF:0000019, GO:0002020=PMID:10620603, GO:0006808=GO_REF:0000019, GO:0042803=PMID:9111042, GO:0042802=PMID:18835031, GO:0043524=PMID:7546744, GO:0048743=GO_REF:0000019, GO:0010039=PMID:11264898, GO:0051924=PMID:8022822, GO:0001662=GO_REF:0000019, GO:0043029=GO_REF:0000019, GO:0033077=GO_REF:0000019, GO:0030336=GO_REF:0000019, GO:0007565=PMID:11530860, GO:0031965=PMID:8402648, GO:0010559=GO_REF:0000019, GO:0007569=GO_REF:0000019, GO:0051384=GO_REF:0000019, GO:0048546=GO_REF:0000019, GO:0046930=PMID:9219694, GO:0045930=GO_REF:0000019, GO:0001952=GO_REF:0000019, GO:0006582=GO_REF:0000019, GO:0031103=GO_REF:0000019, GO:2001234=PMID:20097879, GO:0043375=GO_REF:0000019, GO:0005741=Reactome:REACT_75844, GO:0035872=Reactome:REACT_75913, GO:0032835=GO_REF:0000019, GO:0043583=GO_REF:0000019, GO:0014911=GO_REF:0000019, GO:0005739=PMID:7896880, GO:0001541=GO_REF:0000019, GO:0030279=GO_REF:0000019, GO:0005737=PMID:7546744, GO:0000082=GO_REF:0000019, GO:0031647=GO_REF:0000019, GO:0006470=GO_REF:0000019, GO:0035265=GO_REF:0000019, GO:0048041=GO_REF:0000019, GO:0022612=GO_REF:0000019, GO:0045636=GO_REF:0000019, GO:0034097=PMID:9184696, GO:0021747=GO_REF:0000019, GO:0043066=PMID:9219694, GO:0022898=PMID:9219694, GO:0051881=PMID:9843949, GO:0006915=Reactome:REACT_578, GO:0030318=GO_REF:0000019, GO:0014042=GO_REF:0000019, GO:0097193=Reactome:REACT_964, GO:0032848=PMID:10506221, GO:0003014=GO_REF:0000019, GO:0043565=PMID:12086670, GO:0008584=GO_REF:0000019} P10415 Apoptosis regulator Bcl-2 protein 20110325 {GO:0005515=IPI, GO:0030308=IEA, GO:0030307=IDA, GO:0010523=IEA, GO:0045069=IEA, GO:0051402=TAS, GO:0009791=IEA, GO:0048599=IEA, GO:0031069=IEA, GO:0016337=IEA, GO:0051607=IDA, GO:1900740=TAS, GO:0048589=IEA, GO:0018105=IEA, GO:0018107=IEA, GO:0014031=IEA, GO:0002326=IEA, GO:0033033=IEA, GO:0010332=IEA, GO:0031625=IPI, GO:0000209=IDA, GO:0002320=IEA, GO:0046982=IPI, GO:0071310=IEA, GO:0032469=IEA, GO:0009636=IDA, GO:2001244=TAS, GO:0043085=IEA, GO:0001503=IEA, GO:0070059=IDA, GO:0045087=TAS, GO:0005789=IEA, GO:0016049=IEA, GO:0008134=IEA, GO:0050853=IMP, GO:0001782=IEA, GO:0005783=IDA, GO:0030890=IMP, GO:0005634=IDA, GO:0001836=ISS, GO:0005829=IEA, GO:0033138=IEA, GO:0048873=IEA, GO:0042100=IDA, GO:0051902=TAS, GO:0043209=IEA, GO:0006959=TAS, GO:0001101=IEA, GO:0007015=IEA, GO:0040018=IEA, GO:0051721=IEA, GO:0009314=NAS, GO:0046902=ISS, GO:0051434=IPI, GO:0042493=IDA, GO:0046671=IEA, GO:0072593=IEA, GO:0006974=IMP, GO:0009605=IEA, GO:0016020=IDA, GO:0010224=IEA, GO:0015267=IDA, GO:0035094=IDA, GO:0001656=IEA, GO:0043496=IDA, GO:0008219=IDA, GO:0042542=IEA, GO:0043497=IDA, GO:0001658=IEA, GO:0033689=IEA, GO:0048538=IEA, GO:0048753=IEA, GO:0048536=IEA, GO:0002020=IDA, GO:0006808=IEA, GO:0042803=IPI, GO:0042802=IPI, GO:0043524=IDA, GO:0048743=IEA, GO:0010039=IDA, GO:0051924=IDA, GO:0001662=IEA, GO:0043029=IEA, GO:0033077=IEA, GO:0030336=IEA, GO:0007565=NAS, GO:0031965=IDA, GO:0010559=IEA, GO:0007569=IEA, GO:0051384=IEA, GO:0048546=IEA, GO:0046930=IDA, GO:0045930=IEA, GO:0001952=IEA, GO:0006582=IEA, GO:0031103=IEA, GO:2001234=IMP, GO:0043375=IEA, GO:0005741=TAS, GO:0035872=TAS, GO:0032835=IEA, GO:0043583=IEA, GO:0014911=IEA, GO:0005739=IDA, GO:0001541=IEA, GO:0030279=IEA, GO:0005737=IDA, GO:0000082=IEA, GO:0031647=IEA, GO:0006470=IEA, GO:0035265=IEA, GO:0048041=IEA, GO:0022612=IEA, GO:0045636=IEA, GO:0034097=IDA, GO:0021747=IEA, GO:0043066=IDA, GO:0022898=IDA, GO:0051881=ISS, GO:0006915=TAS, GO:0030318=IEA, GO:0014042=IEA, GO:0097193=TAS, GO:0032848=IDA, GO:0003014=IEA, GO:0043565=IDA, GO:0008584=IEA} B cell homeostasis, B cell lineage commitment, B cell proliferation, B cell receptor signaling pathway, CD8-positive, alpha-beta T cell lineage commitment, G1/S transition of mitotic cell cycle, T cell differentiation in thymus, T cell homeostasis, actin filament organization, apoptotic process, axon regeneration, behavioral fear response, branching involved in ureteric bud morphogenesis, cell aging, cell death, cell growth, cell-cell adhesion, cellular response to organic substance, cochlear nucleus development, defense response to virus, developmental growth, digestive tract morphogenesis, ear development, endoplasmic reticulum calcium ion homeostasis, female pregnancy, focal adhesion assembly, gland morphogenesis, glomerulus development, hair follicle morphogenesis, homeostasis of number of cells within a tissue, humoral immune response, innate immune response, intrinsic apoptotic signaling pathway, intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress, lymphoid progenitor cell differentiation, male gonad development, melanin metabolic process, melanocyte differentiation, mesenchymal cell development, metanephros development, negative regulation of apoptotic process, negative regulation of apoptotic signaling pathway, negative regulation of calcium ion transport into cytosol, negative regulation of cell growth, negative regulation of cell migration, negative regulation of cellular pH reduction, negative regulation of mitochondrial depolarization, negative regulation of mitotic cell cycle, negative regulation of myeloid cell apoptotic process, negative regulation of neuron apoptotic process, negative regulation of ossification, negative regulation of osteoblast proliferation, negative regulation of retinal cell programmed cell death, neuron apoptotic process, nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway, oocyte development, organ growth, ossification, ovarian follicle development, peptidyl-serine phosphorylation, peptidyl-threonine phosphorylation, pigment granule organization, positive regulation of B cell proliferation, positive regulation of catalytic activity, positive regulation of cell growth, positive regulation of intrinsic apoptotic signaling pathway, positive regulation of melanocyte differentiation, positive regulation of multicellular organism growth, positive regulation of neuron maturation, positive regulation of peptidyl-serine phosphorylation, positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway, positive regulation of skeletal muscle fiber development, positive regulation of smooth muscle cell migration, post-embryonic development, protein dephosphorylation, protein polyubiquitination, reactive oxygen species metabolic process, regulation of calcium ion transport, regulation of cell-matrix adhesion, regulation of glycoprotein biosynthetic process, regulation of mitochondrial membrane permeability, regulation of mitochondrial membrane potential, regulation of nitrogen utilization, regulation of protein heterodimerization activity, regulation of protein homodimerization activity, regulation of protein stability, regulation of transmembrane transporter activity, regulation of viral genome replication, release of cytochrome c from mitochondria, renal system process, response to DNA damage stimulus, response to UV-B, response to acid, response to cytokine stimulus, response to drug, response to external stimulus, response to gamma radiation, response to glucocorticoid stimulus, response to hydrogen peroxide, response to iron ion, response to nicotine, response to radiation, response to toxic substance, spleen development, thymus development cytoplasm, cytosol, endoplasmic reticulum, endoplasmic reticulum membrane, membrane, mitochondrial outer membrane, mitochondrion, myelin sheath, nuclear membrane, nucleus, pore complex BH3 domain binding, channel activity, identical protein binding, protease binding, protein binding, protein heterodimerization activity, protein homodimerization activity, protein phosphatase 2A binding, sequence-specific DNA binding, transcription factor binding, ubiquitin protein ligase binding Human BCL2A1 HGNC UniProtKB {GO:0005515=PMID:10753914, GO:0005737=GO_REF:0000039, GO:0043066=GO_REF:0000002, GO:0006915=GO_REF:0000037} Q16548 Bcl-2-related protein A1 protein 20070302 {GO:0005515=IPI, GO:0005737=IEA, GO:0043066=IEA, GO:0006915=IEA} apoptotic process, negative regulation of apoptotic process cytoplasm protein binding Human UniProtKB:Q07812 BCL2L1 ENSEMBL UniProtKB {GO:0005515=PMID:19060904, GO:0007093=PMID:21840391, GO:0008284=GO_REF:0000019, GO:0008283=GO_REF:0000019, GO:0001836=GO_REF:0000019, GO:0005741=Reactome:REACT_75844, GO:0007283=GO_REF:0000019, GO:0071480=GO_REF:0000019, GO:0007281=GO_REF:0000019, GO:0035872=Reactome:REACT_75913, GO:0005829=GO_REF:0000019, GO:0005739=PMID:12011449, GO:0000910=PMID:21840391, GO:0043524=GO_REF:0000019, GO:0001541=GO_REF:0000019, GO:0005737=PMID:20673843, GO:0008637=PMID:9393856, GO:0090201=PMID:21041309, GO:0071230=GO_REF:0000019, GO:0097136=PMID:21199865, GO:0034097=PMID:9184696, GO:0046902=PMID:9843949, GO:0031965=GO_REF:0000039, GO:0043066=PMID:12011449, GO:0005813=PMID:21840391, GO:0031966=GO_REF:0000019, GO:0043065=GO_REF:0000019, GO:0019901=PMID:21840391, GO:0046982=GO_REF:0000019, GO:0051881=PMID:9843949, GO:0071312=GO_REF:0000019, GO:0006915=Reactome:REACT_578, GO:2001244=Reactome:REACT_330, GO:0046898=GO_REF:0000019, GO:0001701=GO_REF:0000019, GO:0097193=Reactome:REACT_964, GO:0009566=GO_REF:0000019, GO:0045087=Reactome:REACT_6802, GO:0090005=PMID:21041309, GO:0016021=GO_REF:0000037, GO:0060154=GO_REF:0000019, GO:0040007=GO_REF:0000019, GO:0008584=GO_REF:0000019} Q9H1R6 Bcl-2-like protein 1 protein 20130413 {GO:0005515=IPI, GO:0007093=IMP, GO:0008284=IEA, GO:0008283=IEA, GO:0001836=IEA, GO:0005741=TAS, GO:0007283=IEA, GO:0071480=IEA, GO:0007281=IEA, GO:0035872=TAS, GO:0005829=IEA, GO:0005739=IDA, GO:0000910=IMP, GO:0043524=IEA, GO:0001541=IEA, GO:0005737=IDA, GO:0008637=TAS, GO:0090201=IC, GO:0071230=IEA, GO:0097136=IDA, GO:0034097=IDA, GO:0046902=IDA, GO:0031965=IEA, GO:0043066=IDA, GO:0005813=IDA, GO:0031966=IEA, GO:0043065=IEA, GO:0019901=IPI, GO:0046982=IEA, GO:0051881=IDA, GO:0071312=IEA, GO:0006915=TAS, GO:2001244=TAS, GO:0046898=IEA, GO:0001701=IEA, GO:0097193=TAS, GO:0009566=IEA, GO:0045087=TAS, GO:0090005=IDA, GO:0016021=IEA, GO:0060154=IEA, GO:0040007=IEA, GO:0008584=IEA} apoptotic mitochondrial changes, apoptotic process, cell proliferation, cellular process regulating host cell cycle in response to virus, cellular response to alkaloid, cellular response to amino acid stimulus, cellular response to gamma radiation, cytokinesis, fertilization, germ cell development, growth, in utero embryonic development, innate immune response, intrinsic apoptotic signaling pathway, male gonad development, mitotic cell cycle checkpoint, negative regulation of apoptotic process, negative regulation of establishment of protein localization to plasma membrane, negative regulation of neuron apoptotic process, negative regulation of release of cytochrome c from mitochondria, nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway, ovarian follicle development, positive regulation of apoptotic process, positive regulation of cell proliferation, positive regulation of intrinsic apoptotic signaling pathway, regulation of mitochondrial membrane permeability, regulation of mitochondrial membrane potential, release of cytochrome c from mitochondria, response to cycloheximide, response to cytokine stimulus, spermatogenesis Bcl-2 family protein complex, centrosome, cytoplasm, cytosol, integral to membrane, mitochondrial membrane, mitochondrial outer membrane, mitochondrion, nuclear membrane protein binding, protein heterodimerization activity, protein kinase binding Human Ensembl:ENSMUSP00000105445 BCL2L10 HGNC UniProtKB {GO:0005739=PMID:11278245, GO:0005515=PMID:11278245, GO:0031965=GO_REF:0000039, GO:0043066=PMID:11278245, GO:0016020=PMID:9878060, GO:0006919=PMID:9829980, GO:0007292=PMID:9878060, GO:0007283=PMID:9878060, GO:0016021=GO_REF:0000037, GO:0005829=PMID:11278245} Q9HD36 Bcl-2-like protein 10 protein 20070302 {GO:0005739=IDA, GO:0005515=IPI, GO:0031965=IEA, GO:0043066=IDA, GO:0016020=TAS, GO:0006919=TAS, GO:0007292=TAS, GO:0007283=TAS, GO:0016021=IEA, GO:0005829=IDA} activation of cysteine-type endopeptidase activity involved in apoptotic process, female gamete generation, negative regulation of apoptotic process, spermatogenesis cytosol, integral to membrane, membrane, mitochondrion, nuclear membrane protein binding Human BCL2L11 BHF-UCL UniProtKB {GO:0005515=PMID:23245996, GO:0008017=GO_REF:0000019, GO:0001783=GO_REF:0000019, GO:0034976=PMID:22761832, GO:0001782=GO_REF:0000019, GO:0005741=Reactome:REACT_21389, GO:0048538=GO_REF:0000019, GO:0030879=GO_REF:0000019, GO:0007283=GO_REF:0000019, GO:0048536=GO_REF:0000019, GO:0005829=Reactome:REACT_13777, GO:0043583=GO_REF:0000019, GO:0005739=GO_REF:0000019, GO:1900740=Reactome:REACT_1650, GO:0043525=GO_REF:0000019, GO:0090200=PMID:21041309, GO:0042475=GO_REF:0000019, GO:0043029=GO_REF:0000019, GO:0002262=GO_REF:0000019, GO:0048066=GO_REF:0000019, GO:0032464=PMID:21041309, GO:0046620=GO_REF:0000019, GO:0048011=Reactome:REACT_13776, GO:0046982=GO_REF:0000019, GO:0001822=GO_REF:0000019, GO:0035148=GO_REF:0000019, GO:0048563=GO_REF:0000019, GO:0006915=Reactome:REACT_13638, GO:2001244=Reactome:REACT_330, GO:0006917=PMID:10381623, GO:0097190=Reactome:REACT_13720, GO:0001701=GO_REF:0000019, GO:0045787=GO_REF:0000019, GO:0097193=Reactome:REACT_964, GO:0012505=GO_REF:0000039, GO:0048070=GO_REF:0000019, GO:0007160=GO_REF:0000019, GO:0007420=GO_REF:0000019, GO:0060154=GO_REF:0000019, GO:0008584=GO_REF:0000019, GO:0019898=GO_REF:0000019} O43521 Bcl-2-like protein 11 protein 20110317 {GO:0005515=IPI, GO:0008017=IEA, GO:0001783=IEA, GO:0034976=IDA, GO:0001782=IEA, GO:0005741=TAS, GO:0048538=IEA, GO:0030879=IEA, GO:0007283=IEA, GO:0048536=IEA, GO:0005829=TAS, GO:0043583=IEA, GO:0005739=IEA, GO:1900740=TAS, GO:0043525=IEA, GO:0090200=IGI, GO:0042475=IEA, GO:0043029=IEA, GO:0002262=IEA, GO:0048066=IEA, GO:0032464=IDA, GO:0046620=IEA, GO:0048011=TAS, GO:0046982=IEA, GO:0001822=IEA, GO:0035148=IEA, GO:0048563=IEA, GO:0006915=TAS, GO:2001244=TAS, GO:0006917=TAS, GO:0097190=TAS, GO:0001701=IEA, GO:0045787=IEA, GO:0097193=TAS, GO:0012505=IEA, GO:0048070=IEA, GO:0007160=IEA, GO:0007420=IEA, GO:0060154=IEA, GO:0008584=IEA, GO:0019898=IEA} B cell apoptotic process, B cell homeostasis, T cell homeostasis, apoptotic process, apoptotic signaling pathway, brain development, cell-matrix adhesion, cellular process regulating host cell cycle in response to virus, developmental pigmentation, ear development, in utero embryonic development, induction of apoptosis, intrinsic apoptotic signaling pathway, kidney development, male gonad development, mammary gland development, myeloid cell homeostasis, neurotrophin TRK receptor signaling pathway, odontogenesis of dentin-containing tooth, positive regulation of cell cycle, positive regulation of intrinsic apoptotic signaling pathway, positive regulation of neuron apoptotic process, positive regulation of protein homooligomerization, positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway, positive regulation of release of cytochrome c from mitochondria, post-embryonic organ morphogenesis, regulation of developmental pigmentation, regulation of organ growth, response to endoplasmic reticulum stress, spermatogenesis, spleen development, thymus development, tube formation cytosol, endomembrane system, extrinsic to membrane, mitochondrial outer membrane, mitochondrion microtubule binding, protein binding, protein heterodimerization activity Human UniProtKB:P70444 BCL2L12 UniProtKB UniProtKB {GO:0006915=GO_REF:0000037} Q9HB09 Bcl-2-like protein 12 protein 20130413 {GO:0006915=IEA} apoptotic process Human UniProtKB-KW:KW-0053 BCL2L13 UniProtKB UniProtKB {GO:0005739=PMID:11262395, GO:0031966=GO_REF:0000039, GO:0006919=PMID:11262395, GO:0005634=GO_REF:0000039, GO:0042981=GO_REF:0000002, GO:0006917=PMID:11262395, GO:0016021=PMID:11262395, GO:0008656=PMID:11262395} Q9BXK5 Bcl-2-like protein 13 protein 20040129 {GO:0005739=NAS, GO:0031966=IEA, GO:0006919=NAS, GO:0005634=IEA, GO:0042981=IEA, GO:0006917=NAS, GO:0016021=IDA, GO:0008656=NAS} activation of cysteine-type endopeptidase activity involved in apoptotic process, induction of apoptosis, regulation of apoptotic process integral to membrane, mitochondrial membrane, mitochondrion, nucleus cysteine-type endopeptidase activator activity involved in apoptotic process Human BCL2L14 HPA UniProtKB {GO:0005515=PMID:17280616, GO:0005737=GO_REF:0000052, GO:0019901=PMID:17280616, GO:0016020=GO_REF:0000037, GO:0043229=PMID:11054413, GO:0006915=PMID:17280616, GO:0042981=GO_REF:0000002, GO:0005829=PMID:11054413, GO:0012505=GO_REF:0000039} Q9BZR8 Apoptosis facilitator Bcl-2-like protein 14 protein 20110516 {GO:0005515=IPI, GO:0005737=IDA, GO:0019901=IPI, GO:0016020=IEA, GO:0043229=IDA, GO:0006915=IDA, GO:0042981=IEA, GO:0005829=IDA, GO:0012505=IEA} apoptotic process, regulation of apoptotic process cytoplasm, cytosol, endomembrane system, intracellular organelle, membrane protein binding, protein kinase binding Human BCL2L2 IntAct UniProtKB {GO:0005515=PMID:21199865, GO:0031966=GO_REF:0000039, GO:0006915=GO_REF:0000019, GO:0042981=GO_REF:0000002, GO:0007283=PMID:8761287, GO:0060011=GO_REF:0000019, GO:0005829=GO_REF:0000019} Q92843 Bcl-2-like protein 2 protein 20130415 {GO:0005515=IPI, GO:0031966=IEA, GO:0006915=IEA, GO:0042981=IEA, GO:0007283=TAS, GO:0060011=IEA, GO:0005829=IEA} Sertoli cell proliferation, apoptotic process, regulation of apoptotic process, spermatogenesis cytosol, mitochondrial membrane protein binding Human UniProtKB:Q07812 BCL2L2-PABPN1 InterPro UniProtKB {GO:0042981=GO_REF:0000002} G3V2X3 Protein BCL2L2-PABPN1 protein 20130413 {GO:0042981=IEA} regulation of apoptotic process Human InterPro:IPR002475|InterPro:IPR003093|InterPro:IPR013280|InterPro:IPR020717|InterPro:IPR020731|InterPro:IPR026298 BCL3 IntAct UniProtKB {GO:0005515=PMID:21988832, GO:0042345=PMID:8196632, GO:0048471=GO_REF:0000039, GO:0003700=GO_REF:0000019, GO:0007249=PMID:8196632, GO:0042088=GO_REF:0000019, GO:0005634=PMID:8196632, GO:0048536=GO_REF:0000019, GO:0005737=PMID:11387332, GO:0032996=PMID:16280327, GO:0030198=GO_REF:0000019, GO:0045944=GO_REF:0000019, GO:0030674=PMID:16306601, GO:0033257=PMID:9407099, GO:0002467=GO_REF:0000019, GO:0042742=GO_REF:0000019, GO:0000060=PMID:16280327, GO:0032729=GO_REF:0000019, GO:0043066=PMID:16384933, GO:0030330=PMID:16384933, GO:0045415=PMID:16306601, GO:0002268=GO_REF:0000019, GO:0042536=GO_REF:0000019, GO:0042832=GO_REF:0000019, GO:0045727=PMID:16384933, GO:0042981=PMID:16732314, GO:0009615=PMID:16306601, GO:0003677=GO_REF:0000019, GO:0006974=PMID:16384933, GO:0006351=PMID:16306601, GO:0042771=PMID:16384933, GO:0043234=PMID:16280327, GO:0010225=PMID:16384933, GO:0051457=PMID:8196632, GO:0045064=GO_REF:0000019, GO:0051101=PMID:9407099, GO:0019730=GO_REF:0000019, GO:0045893=PMID:16384933, GO:0045082=GO_REF:0000019, GO:0045892=PMID:16306601, GO:0002315=GO_REF:0000019, GO:0008134=PMID:8196632, GO:0002455=GO_REF:0000019} P20749 B-cell lymphoma 3 protein protein 20130415 {GO:0005515=IPI, GO:0042345=IEP, GO:0048471=IEA, GO:0003700=IEA, GO:0007249=IDA, GO:0042088=IEA, GO:0005634=IDA, GO:0048536=IEA, GO:0005737=IDA, GO:0032996=IDA, GO:0030198=IEA, GO:0045944=IEA, GO:0030674=TAS, GO:0033257=IDA, GO:0002467=IEA, GO:0042742=IEA, GO:0000060=IMP, GO:0032729=IEA, GO:0043066=IDA, GO:0030330=IMP, GO:0045415=IMP, GO:0002268=IEA, GO:0042536=IEA, GO:0042832=IEA, GO:0045727=IMP, GO:0042981=IDA, GO:0009615=IDA, GO:0003677=IEA, GO:0006974=IDA, GO:0006351=IDA, GO:0042771=IMP, GO:0043234=IDA, GO:0010225=IDA, GO:0051457=NAS, GO:0045064=IEA, GO:0051101=IEP, GO:0019730=IEA, GO:0045893=IDA, GO:0045082=IEA, GO:0045892=IDA, GO:0002315=IEA, GO:0008134=IPI, GO:0002455=IEA} DNA damage response, signal transduction by p53 class mediator, I-kappaB kinase/NF-kappaB cascade, T-helper 1 type immune response, T-helper 2 cell differentiation, antimicrobial humoral response, defense response to bacterium, defense response to protozoan, extracellular matrix organization, follicular dendritic cell differentiation, germinal center formation, humoral immune response mediated by circulating immunoglobulin, intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator, maintenance of protein location in nucleus, marginal zone B cell differentiation, negative regulation of apoptotic process, negative regulation of interleukin-8 biosynthetic process, negative regulation of transcription, DNA-dependent, negative regulation of tumor necrosis factor biosynthetic process, positive regulation of interferon-gamma production, positive regulation of interleukin-10 biosynthetic process, positive regulation of transcription from RNA polymerase II promoter, positive regulation of transcription, DNA-dependent, positive regulation of translation, protein import into nucleus, translocation, regulation of DNA binding, regulation of NF-kappaB import into nucleus, regulation of apoptotic process, response to DNA damage stimulus, response to UV-C, response to virus, spleen development, transcription, DNA-dependent Bcl3-Bcl10 complex, Bcl3/NF-kappaB2 complex, cytoplasm, nucleus, perinuclear region of cytoplasm, protein complex DNA binding, protein binding, protein binding, bridging, sequence-specific DNA binding transcription factor activity, transcription factor binding Human UniProtKB:P56545 BCL6 HPA UniProtKB {GO:0005515=PMID:16147992, GO:0030308=PMID:10490843, GO:0003700=PMID:15577913, GO:0030036=GO_REF:0000019, GO:0008285=GO_REF:0000019, GO:0030890=GO_REF:0000019, GO:0005657=PMID:10490843, GO:0035024=GO_REF:0000019, GO:0005634=GO_REF:0000052, GO:0007283=GO_REF:0000019, GO:0007266=GO_REF:0000019, GO:0048294=GO_REF:0000019, GO:0042092=GO_REF:0000019, GO:0008104=GO_REF:0000019, GO:0043380=GO_REF:0000019, GO:0002829=GO_REF:0000019, GO:0002903=PMID:15577913, GO:0048821=GO_REF:0000019, GO:0030183=GO_REF:0000019, GO:0002467=GO_REF:0000019, GO:0032319=GO_REF:0000019, GO:0002634=PMID:7795255, GO:0000060=PMID:11821949, GO:0032764=GO_REF:0000019, GO:0043066=GO_REF:0000019, GO:0043065=PMID:10490843, GO:0005730=GO_REF:0000052, GO:0050727=GO_REF:0000019, GO:0000122=PMID:11929873, GO:0006974=PMID:15577913, GO:0045749=PMID:10490843, GO:0006351=GO_REF:0000037, GO:0031490=GO_REF:0000019, GO:0043565=PMID:15577913, GO:0000902=GO_REF:0000019, GO:0045629=GO_REF:0000019, GO:0003682=PMID:12097386, GO:0050776=PMID:16455075, GO:0008270=GO_REF:0000002, GO:0045892=PMID:15577913, GO:0051272=GO_REF:0000019, GO:0001953=GO_REF:0000019} P41182 B-cell lymphoma 6 protein protein 20100326 {GO:0005515=IPI, GO:0030308=IDA, GO:0003700=IMP, GO:0030036=IEA, GO:0008285=IEA, GO:0030890=IEA, GO:0005657=IDA, GO:0035024=IEA, GO:0005634=IDA, GO:0007283=IEA, GO:0007266=IEA, GO:0048294=IEA, GO:0042092=IEA, GO:0008104=IEA, GO:0043380=IEA, GO:0002829=IEA, GO:0002903=NAS, GO:0048821=IEA, GO:0030183=IEA, GO:0002467=IEA, GO:0032319=IEA, GO:0002634=NAS, GO:0000060=IGI, GO:0032764=IEA, GO:0043066=IEA, GO:0043065=IDA, GO:0005730=IDA, GO:0050727=IEA, GO:0000122=IDA, GO:0006974=IDA, GO:0045749=NAS, GO:0006351=IEA, GO:0031490=IEA, GO:0043565=IDA, GO:0000902=IEA, GO:0045629=IEA, GO:0003682=IDA, GO:0050776=NAS, GO:0008270=IEA, GO:0045892=IMP, GO:0051272=IEA, GO:0001953=IEA} B cell differentiation, Rho protein signal transduction, actin cytoskeleton organization, cell morphogenesis, erythrocyte development, germinal center formation, negative regulation of B cell apoptotic process, negative regulation of Rho protein signal transduction, negative regulation of S phase of mitotic cell cycle, negative regulation of T-helper 2 cell differentiation, negative regulation of apoptotic process, negative regulation of cell growth, negative regulation of cell proliferation, negative regulation of cell-matrix adhesion, negative regulation of isotype switching to IgE isotypes, negative regulation of mast cell cytokine production, negative regulation of transcription from RNA polymerase II promoter, negative regulation of transcription, DNA-dependent, negative regulation of type 2 immune response, positive regulation of B cell proliferation, positive regulation of apoptotic process, positive regulation of cellular component movement, protein import into nucleus, translocation, protein localization, regulation of Rho GTPase activity, regulation of germinal center formation, regulation of immune response, regulation of inflammatory response, regulation of memory T cell differentiation, response to DNA damage stimulus, spermatogenesis, transcription, DNA-dependent, type 2 immune response nucleolus, nucleus, replication fork chromatin DNA binding, chromatin binding, protein binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, zinc ion binding NOT Human BCL6B UniProtKB UniProtKB {GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0000122=GO_REF:0000019, GO:0003676=GO_REF:0000002, GO:0003677=GO_REF:0000019} Q8N143 B-cell CLL/lymphoma 6 member B protein protein 20130413 {GO:0005634=IEA, GO:0008270=IEA, GO:0000122=IEA, GO:0003676=IEA, GO:0003677=IEA} negative regulation of transcription from RNA polymerase II promoter nucleus DNA binding, nucleic acid binding, zinc ion binding Human UniProtKB-SubCell:SL-0191 BCL7A UniProtKB UniProtKB {GO:0003674=GO_REF:0000015, GO:0005575=GO_REF:0000015, GO:0045892=PMID:15897551} Q4VC05 B-cell CLL/lymphoma 7 protein family member A protein 20070622 {GO:0003674=ND, GO:0005575=ND, GO:0045892=NAS} negative regulation of transcription, DNA-dependent cellular_component molecular_function Human BCL7B UniProtKB UniProtKB {GO:0008150=GO_REF:0000015, GO:0003779=PMID:8605326, GO:0005575=GO_REF:0000015} Q9BQE9 B-cell CLL/lymphoma 7 protein family member B protein 20061106 {GO:0008150=ND, GO:0003779=NAS, GO:0005575=ND} biological_process cellular_component actin binding Human BCL7C UniProtKB UniProtKB {GO:0006915=GO_REF:0000037} Q8WUZ0 B-cell CLL/lymphoma 7 protein family member C protein 20130413 {GO:0006915=IEA} apoptotic process Human UniProtKB-KW:KW-0053 BCL9 BHF-UCL UniProtKB {GO:0005515=PMID:18498752, GO:0005737=GO_REF:0000019, GO:0008013=GO_REF:0000019, GO:0045944=GO_REF:0000019, GO:0014908=GO_REF:0000019, GO:0005634=GO_REF:0000039, GO:0017015=PMID:19328798, GO:0060070=GO_REF:0000019, GO:0035019=GO_REF:0000019} O00512 B-cell CLL/lymphoma 9 protein protein 20091029 {GO:0005515=IPI, GO:0005737=IEA, GO:0008013=IEA, GO:0045944=IEA, GO:0014908=IEA, GO:0005634=IEA, GO:0017015=IMP, GO:0060070=IEA, GO:0035019=IEA} canonical Wnt receptor signaling pathway, myotube differentiation involved in skeletal muscle regeneration, positive regulation of transcription from RNA polymerase II promoter, regulation of transforming growth factor beta receptor signaling pathway, somatic stem cell maintenance cytoplasm, nucleus beta-catenin binding, protein binding NOT Human BCL9L HPA UniProtKB {GO:0008013=PMID:15574752, GO:0045944=PMID:19328798, GO:0003713=PMID:19328798, GO:0022604=PMID:19328798, GO:0010718=PMID:19328798, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0035914=GO_REF:0000019, GO:0060070=GO_REF:0000019, GO:0035019=GO_REF:0000019, GO:0030512=PMID:19328798, GO:0006351=GO_REF:0000037} Q86UU0 B-cell CLL/lymphoma 9-like protein protein 20120912 {GO:0008013=IDA, GO:0045944=IMP, GO:0003713=NAS, GO:0022604=IMP, GO:0010718=IMP, GO:0005730=IDA, GO:0005634=IDA, GO:0035914=IEA, GO:0060070=IEA, GO:0035019=IEA, GO:0030512=IMP, GO:0006351=IEA} canonical Wnt receptor signaling pathway, negative regulation of transforming growth factor beta receptor signaling pathway, positive regulation of epithelial to mesenchymal transition, positive regulation of transcription from RNA polymerase II promoter, regulation of cell morphogenesis, skeletal muscle cell differentiation, somatic stem cell maintenance, transcription, DNA-dependent nucleolus, nucleus beta-catenin binding, transcription coactivator activity NOT Human BCLAF1 HPA UniProtKB {GO:0005515=PMID:15009215, GO:0005737=GO_REF:0000039, GO:0043065=PMID:10330179, GO:2001022=GO_REF:0000002, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0006917=PMID:10330179, GO:0003677=PMID:10330179, GO:0045892=PMID:10330179, GO:0006351=GO_REF:0000037} Q9NYF8 Bcl-2-associated transcription factor 1 protein 20111111 {GO:0005515=IPI, GO:0005737=IEA, GO:0043065=IDA, GO:2001022=IEA, GO:0005730=IDA, GO:0005634=IDA, GO:0006917=TAS, GO:0003677=IDA, GO:0045892=IDA, GO:0006351=IEA} induction of apoptosis, negative regulation of transcription, DNA-dependent, positive regulation of apoptotic process, positive regulation of response to DNA damage stimulus, transcription, DNA-dependent cytoplasm, nucleolus, nucleus DNA binding, protein binding NOT Human BCMO1 BHF-UCL UniProtKB {GO:0035238=PMID:15983114, GO:0004497=GO_REF:0000037, GO:0007603=Reactome:REACT_160125, GO:0042574=PMID:15983114, GO:0042572=GO_REF:0000041, GO:0001523=Reactome:REACT_24968, GO:0046872=GO_REF:0000037, GO:0005829=Reactome:REACT_25117, GO:0003834=Reactome:REACT_25117} Q9HAY6 Beta,beta-carotene 15,15'-monooxygenase protein 20120626 {GO:0035238=NAS, GO:0004497=IEA, GO:0007603=TAS, GO:0042574=NAS, GO:0042572=IEA, GO:0001523=TAS, GO:0046872=IEA, GO:0005829=TAS, GO:0003834=TAS} phototransduction, visible light, retinal metabolic process, retinoid metabolic process, retinol metabolic process, vitamin A biosynthetic process cytosol beta-carotene 15,15'-monooxygenase activity, metal ion binding, monooxygenase activity Human BCOR IntAct UniProtKB {GO:0031519=PMID:16943429, GO:0005515=PMID:16943429, GO:0035518=PMID:16943429, GO:0000415=PMID:19578371, GO:0004842=PMID:16943429, GO:0044212=PMID:19578371, GO:0042826=PMID:10898795, GO:0003714=PMID:15878880, GO:0070171=PMID:19578371, GO:0005634=PMID:10898795, GO:0000122=PMID:19578371, GO:0030502=PMID:19578371, GO:0006351=GO_REF:0000037, GO:0065001=PMID:17517692, GO:0007507=PMID:17517692, GO:0031072=PMID:16943429, GO:0051572=PMID:19578371, GO:0042476=PMID:17517692, GO:0060021=PMID:17517692, GO:0045892=PMID:15878880, GO:0008134=PMID:10898795} Q6W2J9 BCL-6 corepressor protein 20130415 {GO:0031519=IDA, GO:0005515=IPI, GO:0035518=IDA, GO:0000415=IMP, GO:0004842=IDA, GO:0044212=IMP, GO:0042826=IPI, GO:0003714=IMP, GO:0070171=IMP, GO:0005634=IDA, GO:0000122=IMP, GO:0030502=IMP, GO:0006351=IEA, GO:0065001=IMP, GO:0007507=IMP, GO:0031072=IDA, GO:0051572=IMP, GO:0042476=IMP, GO:0060021=IMP, GO:0045892=IMP, GO:0008134=IPI} heart development, histone H2A monoubiquitination, negative regulation of bone mineralization, negative regulation of histone H3-K36 methylation, negative regulation of histone H3-K4 methylation, negative regulation of tooth mineralization, negative regulation of transcription from RNA polymerase II promoter, negative regulation of transcription, DNA-dependent, odontogenesis, palate development, specification of axis polarity, transcription, DNA-dependent PcG protein complex, nucleus heat shock protein binding, histone deacetylase binding, protein binding, transcription corepressor activity, transcription factor binding, transcription regulatory region DNA binding, ubiquitin-protein ligase activity Human UniProtKB:Q9BSM1 BCORL1 HPA UniProtKB {GO:0005737=GO_REF:0000052, GO:0006355=GO_REF:0000037, GO:0005886=GO_REF:0000052, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0006351=GO_REF:0000037, GO:0016568=GO_REF:0000037} Q5H9F3 BCL-6 corepressor-like protein 1 protein 20110516 {GO:0005737=IDA, GO:0006355=IEA, GO:0005886=IDA, GO:0005730=IDA, GO:0005634=IDA, GO:0006351=IEA, GO:0016568=IEA} chromatin modification, regulation of transcription, DNA-dependent, transcription, DNA-dependent cytoplasm, nucleolus, nucleus, plasma membrane Human BCR IntAct UniProtKB {GO:0005515=PMID:22153077, GO:0043314=GO_REF:0000019, GO:0030036=GO_REF:0000019, GO:0005886=GO_REF:0000019, GO:0007264=Reactome:REACT_11044, GO:0035023=GO_REF:0000002, GO:0005829=Reactome:REACT_121389, GO:0035556=GO_REF:0000002, GO:0005622=GO_REF:0000002, GO:0050766=GO_REF:0000019, GO:0005543=GO_REF:0000002, GO:0046777=GO_REF:0000019, GO:0016301=Reactome:REACT_120831, GO:0032496=GO_REF:0000019, GO:0050885=GO_REF:0000019, GO:0051726=GO_REF:0000019, GO:0005089=GO_REF:0000002, GO:0030675=GO_REF:0000019, GO:0051056=Reactome:REACT_11051, GO:0030336=GO_REF:0000019, GO:0042472=GO_REF:0000019, GO:0005524=GO_REF:0000037, GO:0007165=PMID:1657398, GO:0007420=GO_REF:0000019, GO:0004674=GO_REF:0000037, GO:0050728=GO_REF:0000019, GO:0006468=PMID:1657398, GO:0004713=Reactome:REACT_121389, GO:0048008=GO_REF:0000019, GO:0019899=GO_REF:0000019, GO:0005096=PMID:1903516} P11274 Breakpoint cluster region protein protein 20130415 {GO:0005515=IPI, GO:0043314=IEA, GO:0030036=IEA, GO:0005886=IEA, GO:0007264=TAS, GO:0035023=IEA, GO:0005829=TAS, GO:0035556=IEA, GO:0005622=IEA, GO:0050766=IEA, GO:0005543=IEA, GO:0046777=IEA, GO:0016301=TAS, GO:0032496=IEA, GO:0050885=IEA, GO:0051726=IEA, GO:0005089=IEA, GO:0030675=IEA, GO:0051056=TAS, GO:0030336=IEA, GO:0042472=IEA, GO:0005524=IEA, GO:0007165=TAS, GO:0007420=IEA, GO:0004674=IEA, GO:0050728=IEA, GO:0006468=TAS, GO:0004713=TAS, GO:0048008=IEA, GO:0019899=IEA, GO:0005096=TAS} actin cytoskeleton organization, brain development, inner ear morphogenesis, intracellular signal transduction, negative regulation of cell migration, negative regulation of inflammatory response, negative regulation of neutrophil degranulation, neuromuscular process controlling balance, platelet-derived growth factor receptor signaling pathway, positive regulation of phagocytosis, protein autophosphorylation, protein phosphorylation, regulation of Rho protein signal transduction, regulation of cell cycle, regulation of small GTPase mediated signal transduction, response to lipopolysaccharide, signal transduction, small GTPase mediated signal transduction cytosol, intracellular, plasma membrane ATP binding, GTPase activator activity, Rac GTPase activator activity, Rho guanyl-nucleotide exchange factor activity, enzyme binding, kinase activity, phospholipid binding, protein binding, protein serine/threonine kinase activity, protein tyrosine kinase activity Human UniProtKB:Q9H2K2 BCS1L PINC UniProtKB {GO:0005515=PMID:18628306, GO:0033617=PMID:18628306, GO:0005739=PMID:18628306, GO:0032981=PMID:18628306, GO:0017111=GO_REF:0000002, GO:0034551=PMID:18628306, GO:0005750=PMID:9878253, GO:0007005=PMID:18628306, GO:0016021=GO_REF:0000037, GO:0005524=GO_REF:0000037} Q9Y276 Mitochondrial chaperone BCS1 protein 20030904 {GO:0005515=IPI, GO:0033617=IMP, GO:0005739=IDA, GO:0032981=IMP, GO:0017111=IEA, GO:0034551=IMP, GO:0005750=TAS, GO:0007005=IMP, GO:0016021=IEA, GO:0005524=IEA} mitochondrial respiratory chain complex I assembly, mitochondrial respiratory chain complex III assembly, mitochondrial respiratory chain complex IV assembly, mitochondrion organization integral to membrane, mitochondrial respiratory chain complex III, mitochondrion ATP binding, nucleoside-triphosphatase activity, protein binding Human BDH1 HPA UniProtKB {GO:0045471=GO_REF:0000019, GO:0005743=GO_REF:0000019, GO:0005634=GO_REF:0000052, GO:0044281=Reactome:REACT_111217, GO:0005739=GO_REF:0000052, GO:0042594=GO_REF:0000019, GO:0005543=GO_REF:0000019, GO:0005759=Reactome:REACT_1493, GO:0032355=GO_REF:0000019, GO:0044255=Reactome:REACT_22279, GO:0051412=GO_REF:0000019, GO:0032868=GO_REF:0000019, GO:0060416=GO_REF:0000019, GO:0007584=GO_REF:0000019, GO:0042493=GO_REF:0000019, GO:0005730=GO_REF:0000052, GO:0009636=GO_REF:0000019, GO:0003858=Reactome:REACT_1493, GO:0001889=GO_REF:0000019, GO:0046952=Reactome:REACT_59, GO:0007420=GO_REF:0000019, GO:0046951=Reactome:REACT_1464, GO:0008152=GO_REF:0000029, GO:0046950=Reactome:REACT_1861, GO:0016491=GO_REF:0000038, GO:0060612=GO_REF:0000019, GO:0046686=GO_REF:0000019} Q02338 D-beta-hydroxybutyrate dehydrogenase, mitochondrial protein 20101115 {GO:0045471=IEA, GO:0005743=IEA, GO:0005634=IDA, GO:0044281=TAS, GO:0005739=IDA, GO:0042594=IEA, GO:0005543=IEA, GO:0005759=TAS, GO:0032355=IEA, GO:0044255=TAS, GO:0051412=IEA, GO:0032868=IEA, GO:0060416=IEA, GO:0007584=IEA, GO:0042493=IEA, GO:0005730=IDA, GO:0009636=IEA, GO:0003858=TAS, GO:0001889=IEA, GO:0046952=TAS, GO:0007420=IEA, GO:0046951=TAS, GO:0008152=TAS, GO:0046950=TAS, GO:0016491=IEA, GO:0060612=IEA, GO:0046686=IEA} adipose tissue development, brain development, cellular ketone body metabolic process, cellular lipid metabolic process, ketone body biosynthetic process, ketone body catabolic process, liver development, metabolic process, response to cadmium ion, response to corticosterone stimulus, response to drug, response to estradiol stimulus, response to ethanol, response to growth hormone stimulus, response to insulin stimulus, response to nutrient, response to starvation, response to toxic substance, small molecule metabolic process mitochondrial inner membrane, mitochondrial matrix, mitochondrion, nucleolus, nucleus 3-hydroxybutyrate dehydrogenase activity, oxidoreductase activity, phospholipid binding Human BDH2 HGNC UniProtKB {GO:0005739=PMID:16380372, GO:0005737=PMID:16380372, GO:0051287=PMID:16380372, GO:0006635=PMID:16380372, GO:0016491=GO_REF:0000002, GO:0003858=PMID:16380372, GO:0042168=GO_REF:0000024, GO:0008667=GO_REF:0000002, GO:0016628=GO_REF:0000024, GO:0055072=GO_REF:0000024, GO:0019290=GO_REF:0000024} Q9BUT1 3-hydroxybutyrate dehydrogenase type 2 protein 20060116 {GO:0005739=IDA, GO:0005737=IDA, GO:0051287=IDA, GO:0006635=IDA, GO:0016491=IEA, GO:0003858=IDA, GO:0042168=ISS, GO:0008667=IEA, GO:0016628=ISS, GO:0055072=ISS, GO:0019290=ISS} fatty acid beta-oxidation, heme metabolic process, iron ion homeostasis, siderophore biosynthetic process cytoplasm, mitochondrion 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase activity, 3-hydroxybutyrate dehydrogenase activity, NAD binding, oxidoreductase activity, oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor NOT Human BDKRB1 Reactome UniProtKB {GO:0043005=GO_REF:0000019, GO:0004947=GO_REF:0000019, GO:0042277=GO_REF:0000019, GO:0030308=GO_REF:0000019, GO:0005886=Reactome:REACT_22436, GO:0005783=PMID:9930991, GO:0006950=GO_REF:0000002, GO:0045776=GO_REF:0000019, GO:0007204=GO_REF:0000002, GO:0007205=GO_REF:0000019, GO:0019233=GO_REF:0000019, GO:0006954=GO_REF:0000019, GO:0016477=GO_REF:0000019, GO:0005887=PMID:8063797, GO:0002687=GO_REF:0000019, GO:0032496=GO_REF:0000019, GO:0001933=GO_REF:0000019, GO:0016021=GO_REF:0000002, GO:0051281=GO_REF:0000019} P46663 B1 bradykinin receptor protein 20080728 {GO:0043005=IEA, GO:0004947=IEA, GO:0042277=IEA, GO:0030308=IEA, GO:0005886=TAS, GO:0005783=TAS, GO:0006950=IEA, GO:0045776=IEA, GO:0007204=IEA, GO:0007205=IEA, GO:0019233=IEA, GO:0006954=IEA, GO:0016477=IEA, GO:0005887=TAS, GO:0002687=IEA, GO:0032496=IEA, GO:0001933=IEA, GO:0016021=IEA, GO:0051281=IEA} cell migration, elevation of cytosolic calcium ion concentration, inflammatory response, negative regulation of blood pressure, negative regulation of cell growth, negative regulation of protein phosphorylation, positive regulation of leukocyte migration, positive regulation of release of sequestered calcium ion into cytosol, protein kinase C-activating G-protein coupled receptor signaling pathway, response to lipopolysaccharide, response to stress, sensory perception of pain endoplasmic reticulum, integral to membrane, integral to plasma membrane, neuron projection, plasma membrane bradykinin receptor activity, peptide binding Human BDKRB2 BHF-UCL UniProtKB {GO:0005515=PMID:18672896, GO:0004947=PMID:17077303, GO:0043066=GO_REF:0000019, GO:0009651=GO_REF:0000019, GO:0046982=PMID:10993080, GO:0005886=PMID:17077303, GO:0008015=PMID:7835885, GO:0002020=PMID:17077303, GO:0031702=PMID:10993080, GO:0007204=GO_REF:0000002, GO:0019229=PMID:17077303, GO:0006939=PMID:17077303, GO:0006954=PMID:17077303, GO:0007186=PMID:1314587, GO:0005887=PMID:7916737, GO:0004435=PMID:8302267, GO:0033137=GO_REF:0000019, GO:0043114=PMID:17077303, GO:0007169=PMID:10653985, GO:0007166=PMID:7916737, GO:0050482=PMID:17077303, GO:0005768=PMID:17077303} P30411 B2 bradykinin receptor protein 20080519 {GO:0005515=IPI, GO:0004947=IDA, GO:0043066=IEA, GO:0009651=IEA, GO:0046982=IPI, GO:0005886=IDA, GO:0008015=NAS, GO:0002020=IPI, GO:0031702=IPI, GO:0007204=IEA, GO:0019229=IC, GO:0006939=IC, GO:0006954=IC, GO:0007186=TAS, GO:0005887=TAS, GO:0004435=TAS, GO:0033137=IEA, GO:0043114=IC, GO:0007169=TAS, GO:0007166=TAS, GO:0050482=IDA, GO:0005768=IDA} G-protein coupled receptor signaling pathway, arachidonic acid secretion, blood circulation, cell surface receptor signaling pathway, elevation of cytosolic calcium ion concentration, inflammatory response, negative regulation of apoptotic process, negative regulation of peptidyl-serine phosphorylation, regulation of vascular permeability, regulation of vasoconstriction, response to salt stress, smooth muscle contraction, transmembrane receptor protein tyrosine kinase signaling pathway endosome, integral to plasma membrane, plasma membrane bradykinin receptor activity, phosphatidylinositol phospholipase C activity, protease binding, protein binding, protein heterodimerization activity, type 1 angiotensin receptor binding Human UniProtKB:P30556 BDNF UniProtKB UniProtKB {GO:0007631=GO_REF:0000019, GO:0001657=GO_REF:0000019, GO:0048471=GO_REF:0000024, GO:0008038=GO_REF:0000019, GO:0033189=GO_REF:0000019, GO:0019222=GO_REF:0000019, GO:0021675=GO_REF:0000019, GO:0007406=GO_REF:0000019, GO:0014076=GO_REF:0000019, GO:0042596=GO_REF:0000019, GO:0005737=GO_REF:0000024, GO:0007412=GO_REF:0000019, GO:0043524=GO_REF:0000019, GO:0007411=GO_REF:0000019, GO:0007611=GO_REF:0000019, GO:0006120=GO_REF:0000019, GO:0072347=GO_REF:0000019, GO:0009725=GO_REF:0000019, GO:0051965=PMID:19036963, GO:0001666=GO_REF:0000019, GO:0048839=GO_REF:0000019, GO:0042490=GO_REF:0000019, GO:0005169=GO_REF:0000019, GO:0060079=GO_REF:0000019, GO:0005576=GO_REF:0000039, GO:0002544=GO_REF:0000019, GO:0014047=GO_REF:0000019, GO:0016358=GO_REF:0000019, GO:0007399=PMID:2236018, GO:0008021=GO_REF:0000019, GO:0045843=GO_REF:0000019, GO:0045666=GO_REF:0000019, GO:0055093=GO_REF:0000019, GO:0048172=GO_REF:0000019, GO:0008083=GO_REF:0000038, GO:0046668=GO_REF:0000019, GO:0048170=GO_REF:0000019} Q6YNR1 Brain-derived neurotrophic factor BDNF7 protein 20130413 {GO:0007631=IEA, GO:0001657=IEA, GO:0048471=ISS, GO:0008038=IEA, GO:0033189=IEA, GO:0019222=IEA, GO:0021675=IEA, GO:0007406=IEA, GO:0014076=IEA, GO:0042596=IEA, GO:0005737=ISS, GO:0007412=IEA, GO:0043524=IEA, GO:0007411=IEA, GO:0007611=IEA, GO:0006120=IEA, GO:0072347=IEA, GO:0009725=IEA, GO:0051965=IDA, GO:0001666=IEA, GO:0048839=IEA, GO:0042490=IEA, GO:0005169=IEA, GO:0060079=IEA, GO:0005576=IEA, GO:0002544=IEA, GO:0014047=IEA, GO:0016358=IEA, GO:0007399=TAS, GO:0008021=IEA, GO:0045843=IEA, GO:0045666=IEA, GO:0055093=IEA, GO:0048172=IEA, GO:0008083=IEA, GO:0046668=IEA, GO:0048170=IEA} axon guidance, axon target recognition, chronic inflammatory response, dendrite development, fear response, feeding behavior, glutamate secretion, inner ear development, learning or memory, mechanoreceptor differentiation, mitochondrial electron transport, NADH to ubiquinone, negative regulation of neuroblast proliferation, negative regulation of neuron apoptotic process, negative regulation of striated muscle tissue development, nerve development, nervous system development, neuron recognition, positive regulation of long-term neuronal synaptic plasticity, positive regulation of neuron differentiation, positive regulation of synapse assembly, regulation of excitatory postsynaptic membrane potential, regulation of metabolic process, regulation of retinal cell programmed cell death, regulation of short-term neuronal synaptic plasticity, response to anesthetic, response to fluoxetine, response to hormone stimulus, response to hyperoxia, response to hypoxia, response to vitamin A, ureteric bud development cytoplasm, extracellular region, perinuclear region of cytoplasm, synaptic vesicle growth factor activity, neurotrophin TRKB receptor binding Human UniProtKB-KW:KW-0339 BDP1 Reactome UniProtKB {GO:0010467=Reactome:REACT_71, GO:0006355=GO_REF:0000037, GO:0003682=GO_REF:0000002, GO:0005654=Reactome:REACT_1779, GO:0006383=Reactome:REACT_1371, GO:0003677=GO_REF:0000002} A6H8Y1 Transcription factor TFIIIB component B'' homolog protein 20130213 {GO:0010467=TAS, GO:0006355=IEA, GO:0003682=IEA, GO:0005654=TAS, GO:0006383=TAS, GO:0003677=IEA} gene expression, regulation of transcription, DNA-dependent, transcription from RNA polymerase III promoter nucleoplasm DNA binding, chromatin binding Human BEAN1 UniProtKB UniProtKB {GO:0008219=GO_REF:0000037, GO:0016021=GO_REF:0000037} Q3B7T3 Protein BEAN1 protein 20130413 {GO:0008219=IEA, GO:0016021=IEA} cell death integral to membrane Human UniProtKB-KW:KW-0812 BECN1 IntAct UniProtKB {GO:0005802=GO_REF:0000019, GO:0005515=PMID:21241894, GO:0008285=GO_REF:0000019, GO:0005634=GO_REF:0000019, GO:0030425=GO_REF:0000019, GO:0000910=PMID:20208530, GO:0051607=GO_REF:0000037, GO:0048666=GO_REF:0000019, GO:0033197=GO_REF:0000019, GO:0071275=GO_REF:0000019, GO:0000045=GO_REF:0000019, GO:0016239=GO_REF:0000019, GO:0001666=GO_REF:0000019, GO:0043066=PMID:9765397, GO:0005794=GO_REF:0000039, GO:0042493=GO_REF:0000019, GO:0006914=GO_REF:0000002, GO:0050435=GO_REF:0000019, GO:0043234=GO_REF:0000019, GO:0007049=GO_REF:0000037, GO:0006968=PMID:9765397, GO:0016020=GO_REF:0000037, GO:0019048=GO_REF:0000037, GO:0016023=GO_REF:0000019, GO:0007040=GO_REF:0000019} Q14457 Beclin-1 protein 20130415 {GO:0005802=IEA, GO:0005515=IPI, GO:0008285=IEA, GO:0005634=IEA, GO:0030425=IEA, GO:0000910=IMP, GO:0051607=IEA, GO:0048666=IEA, GO:0033197=IEA, GO:0071275=IEA, GO:0000045=IEA, GO:0016239=IEA, GO:0001666=IEA, GO:0043066=TAS, GO:0005794=IEA, GO:0042493=IEA, GO:0006914=IEA, GO:0050435=IEA, GO:0043234=IEA, GO:0007049=IEA, GO:0006968=TAS, GO:0016020=IEA, GO:0019048=IEA, GO:0016023=IEA, GO:0007040=IEA} autophagic vacuole assembly, autophagy, beta-amyloid metabolic process, cell cycle, cellular defense response, cellular response to aluminum ion, cytokinesis, defense response to virus, lysosome organization, negative regulation of apoptotic process, negative regulation of cell proliferation, neuron development, positive regulation of macroautophagy, response to drug, response to hypoxia, response to vitamin E, virus-host interaction Golgi apparatus, cytoplasmic membrane-bounded vesicle, dendrite, membrane, nucleus, protein complex, trans-Golgi network protein binding Human UniProtKB:Q8IYI6 BEGAIN IntAct UniProtKB {GO:0005515=PMID:16189514, GO:0005737=GO_REF:0000039, GO:0016020=GO_REF:0000039, GO:0016301=GO_REF:0000038, GO:0043025=GO_REF:0000019, GO:0030425=GO_REF:0000019} Q9BUH8 Brain-enriched guanylate kinase-associated protein protein 20130415 {GO:0005515=IPI, GO:0005737=IEA, GO:0016020=IEA, GO:0016301=IEA, GO:0043025=IEA, GO:0030425=IEA} cytoplasm, dendrite, membrane, neuronal cell body kinase activity, protein binding Human UniProtKB:P28749 BEND2 null null {} null null null null {} null null null BEND3 null null {} null null null null {} null null null BEND5 ENSEMBL UniProtKB {GO:0005794=GO_REF:0000019} Q7L4P6 BEN domain-containing protein 5 protein 20130413 {GO:0005794=IEA} Golgi apparatus Human Ensembl:ENSMUSP00000030274 BEND7 IntAct UniProtKB {GO:0005515=PMID:19060904} Q8N7W2 BEN domain-containing protein 7 protein 20130415 {GO:0005515=IPI} protein binding Human UniProtKB:Q9GZT8 BEST1 HGNC UniProtKB {GO:0030321=PMID:17003041, GO:0006821=PMID:17003041, GO:0005886=Reactome:REACT_160220, GO:0034707=GO_REF:0000037, GO:0055085=Reactome:REACT_15518, GO:0005254=PMID:17003041, GO:0005829=PMID:17003041, GO:0016323=PMID:19853238, GO:0034220=Reactome:REACT_25300, GO:0016020=PMID:10737974, GO:0050908=GO_REF:0000019, GO:0051924=GO_REF:0000019, GO:0016021=PMID:10737974, GO:0007601=PMID:9662395} O76090 Bestrophin-1 protein 20071022 {GO:0030321=IDA, GO:0006821=IDA, GO:0005886=TAS, GO:0034707=IEA, GO:0055085=TAS, GO:0005254=IDA, GO:0005829=TAS, GO:0016323=IDA, GO:0034220=TAS, GO:0016020=TAS, GO:0050908=IEA, GO:0051924=IEA, GO:0016021=TAS, GO:0007601=TAS} chloride transport, detection of light stimulus involved in visual perception, ion transmembrane transport, regulation of calcium ion transport, transepithelial chloride transport, transmembrane transport, visual perception basolateral plasma membrane, chloride channel complex, cytosol, integral to membrane, membrane, plasma membrane chloride channel activity Human BEST4 UniProtKB UniProtKB {GO:0003674=GO_REF:0000015, GO:0008150=GO_REF:0000015, GO:0005886=GO_REF:0000039, GO:0034707=GO_REF:0000037, GO:0005254=GO_REF:0000037} Q8NFU0 Bestrophin-4 protein 20061026 {GO:0003674=ND, GO:0008150=ND, GO:0005886=IEA, GO:0034707=IEA, GO:0005254=IEA} biological_process chloride channel complex, plasma membrane chloride channel activity, molecular_function Human BET1 IntAct UniProtKB {GO:0005515=PMID:16189514, GO:0006888=GO_REF:0000019, GO:0005801=GO_REF:0000019, GO:0000139=GO_REF:0000039, GO:0005789=GO_REF:0000039, GO:0031985=GO_REF:0000019, GO:0048280=GO_REF:0000019, GO:0016021=GO_REF:0000019, GO:0015031=GO_REF:0000037} O15155 BET1 homolog protein 20130415 {GO:0005515=IPI, GO:0006888=IEA, GO:0005801=IEA, GO:0000139=IEA, GO:0005789=IEA, GO:0031985=IEA, GO:0048280=IEA, GO:0016021=IEA, GO:0015031=IEA} ER to Golgi vesicle-mediated transport, protein transport, vesicle fusion with Golgi apparatus Golgi cisterna, Golgi membrane, cis-Golgi network, endoplasmic reticulum membrane, integral to membrane protein binding Human UniProtKB:Q8N6Y0 BET1L HPA UniProtKB {GO:0005484=PMID:15215310, GO:0030173=GO_REF:0000019, GO:0005794=GO_REF:0000052, GO:0005795=GO_REF:0000019, GO:0042147=PMID:15215310, GO:0031201=PMID:15215310, GO:0005634=GO_REF:0000052, GO:0015031=GO_REF:0000037, GO:0005768=PMID:15215310} Q9NYM9 BET1-like protein protein 20110516 {GO:0005484=IDA, GO:0030173=IEA, GO:0005794=IDA, GO:0005795=IEA, GO:0042147=IDA, GO:0031201=TAS, GO:0005634=IDA, GO:0015031=IEA, GO:0005768=IDA} protein transport, retrograde transport, endosome to Golgi Golgi apparatus, Golgi stack, SNARE complex, endosome, integral to Golgi membrane, nucleus SNAP receptor activity Human BET3L UniProtKB UniProtKB {GO:0005794=GO_REF:0000039, GO:0005783=GO_REF:0000039, GO:0016192=GO_REF:0000037} Q5T215 Trafficking protein particle complex subunit 3-like protein protein 20130413 {GO:0005794=IEA, GO:0005783=IEA, GO:0016192=IEA} vesicle-mediated transport Golgi apparatus, endoplasmic reticulum Human UniProtKB-SubCell:SL-0132 BEX1 BHF-UCL UniProtKB {GO:0005667=PMID:16314316, GO:0001102=PMID:16314316, GO:0051091=PMID:16314316, GO:0005737=GO_REF:0000039, GO:0045944=PMID:16314316, GO:0030154=GO_REF:0000037, GO:0007399=GO_REF:0000037} Q9HBH7 Protein BEX1 protein 20111208 {GO:0005667=IDA, GO:0001102=IPI, GO:0051091=IDA, GO:0005737=IEA, GO:0045944=IDA, GO:0030154=IEA, GO:0007399=IEA} cell differentiation, nervous system development, positive regulation of sequence-specific DNA binding transcription factor activity, positive regulation of transcription from RNA polymerase II promoter cytoplasm, transcription factor complex RNA polymerase II activating transcription factor binding Human BEX2 UniProtKB UniProtKB {GO:0005737=GO_REF:0000039, GO:0007049=GO_REF:0000037, GO:0051726=PMID:19711341, GO:0006915=GO_REF:0000037, GO:0042981=PMID:19711341, GO:0005634=GO_REF:0000039} Q9BXY8 Protein BEX2 protein 20100201 {GO:0005737=IEA, GO:0007049=IEA, GO:0051726=IDA, GO:0006915=IEA, GO:0042981=IDA, GO:0005634=IEA} apoptotic process, cell cycle, regulation of apoptotic process, regulation of cell cycle cytoplasm, nucleus Human BEX4 UniProtKB UniProtKB {GO:0005737=GO_REF:0000039, GO:0005634=GO_REF:0000039} Q9NWD9 Protein BEX4 protein 20130413 {GO:0005737=IEA, GO:0005634=IEA} cytoplasm, nucleus Human UniProtKB-SubCell:SL-0086 BFAR MGI UniProtKB {GO:0043066=PMID:10716992, GO:0016020=PMID:10716992, GO:0005887=PMID:10716992, GO:0005198=PMID:10716992, GO:0005789=GO_REF:0000039, GO:0006915=GO_REF:0000037, GO:0008270=GO_REF:0000002} Q9NZS9 Bifunctional apoptosis regulator protein 20060110 {GO:0043066=IDA, GO:0016020=IDA, GO:0005887=TAS, GO:0005198=TAS, GO:0005789=IEA, GO:0006915=IEA, GO:0008270=IEA} apoptotic process, negative regulation of apoptotic process endoplasmic reticulum membrane, integral to plasma membrane, membrane structural molecule activity, zinc ion binding Human BFSP1 HPA UniProtKB {GO:0005739=GO_REF:0000052, GO:0005882=GO_REF:0000019, GO:0008150=GO_REF:0000015, GO:0005737=GO_REF:0000052, GO:0005212=GO_REF:0000019, GO:0005886=GO_REF:0000052, GO:0070307=GO_REF:0000019, GO:0005200=PMID:9628810, GO:0048469=GO_REF:0000019, GO:0015629=GO_REF:0000052} Q12934 Filensin protein 20111111 {GO:0005739=IDA, GO:0005882=IEA, GO:0008150=ND, GO:0005737=IDA, GO:0005212=IEA, GO:0005886=IDA, GO:0070307=IEA, GO:0005200=TAS, GO:0048469=IEA, GO:0015629=IDA} biological_process, cell maturation, lens fiber cell development actin cytoskeleton, cytoplasm, intermediate filament, mitochondrion, plasma membrane structural constituent of cytoskeleton, structural constituent of eye lens Human BFSP2 HPA UniProtKB {GO:0005882=GO_REF:0000037, GO:0005737=GO_REF:0000052, GO:0005212=GO_REF:0000019, GO:0005886=GO_REF:0000052, GO:0070307=GO_REF:0000019, GO:0045104=GO_REF:0000019, GO:0005200=PMID:9628810, GO:0048469=GO_REF:0000019, GO:0007601=GO_REF:0000037, GO:0050896=GO_REF:0000037} Q13515 Phakinin protein 20110516 {GO:0005882=IEA, GO:0005737=IDA, GO:0005212=IEA, GO:0005886=IDA, GO:0070307=IEA, GO:0045104=IEA, GO:0005200=TAS, GO:0048469=IEA, GO:0007601=IEA, GO:0050896=IEA} cell maturation, intermediate filament cytoskeleton organization, lens fiber cell development, response to stimulus, visual perception cytoplasm, intermediate filament, plasma membrane structural constituent of cytoskeleton, structural constituent of eye lens Human BGLAP BHF-UCL UniProtKB {GO:0043627=GO_REF:0000019, GO:0045471=GO_REF:0000019, GO:0045124=PMID:10486212, GO:0033280=PMID:17023519, GO:0030282=PMID:10486212, GO:0010043=GO_REF:0000019, GO:0005615=GO_REF:0000019, GO:0030425=GO_REF:0000019, GO:0033594=GO_REF:0000019, GO:0071305=GO_REF:0000019, GO:0046848=PMID:10486212, GO:0042476=PMID:11856645, GO:0043204=GO_REF:0000019, GO:0008147=PMID:12467198, GO:0007155=PMID:12202187, GO:0005791=GO_REF:0000019, GO:0014823=GO_REF:0000019, GO:0030500=GO_REF:0000002, GO:0005794=GO_REF:0000019, GO:0007569=GO_REF:0000019, GO:0042493=GO_REF:0000019, GO:0031988=GO_REF:0000019, GO:0005509=GO_REF:0000002, GO:0005576=PMID:11856645, GO:0051384=GO_REF:0000019, GO:0045670=PMID:10486212, GO:0033574=GO_REF:0000019, GO:0001649=PMID:17023519, GO:0009612=GO_REF:0000019, GO:0060348=GO_REF:0000019, GO:0001501=PMID:10865224, GO:0002076=GO_REF:0000019, GO:0071363=GO_REF:0000019, GO:0009629=GO_REF:0000019, GO:0005198=PMID:10486212, GO:0032571=GO_REF:0000019} P02818 Osteocalcin protein 20090507 {GO:0043627=IEA, GO:0045471=IEA, GO:0045124=NAS, GO:0033280=IEP, GO:0030282=NAS, GO:0010043=IEA, GO:0005615=IEA, GO:0030425=IEA, GO:0033594=IEA, GO:0071305=IEA, GO:0046848=NAS, GO:0042476=NAS, GO:0043204=IEA, GO:0008147=NAS, GO:0007155=NAS, GO:0005791=IEA, GO:0014823=IEA, GO:0030500=IEA, GO:0005794=IEA, GO:0007569=IEA, GO:0042493=IEA, GO:0031988=IEA, GO:0005509=IEA, GO:0005576=NAS, GO:0051384=IEA, GO:0045670=NAS, GO:0033574=IEA, GO:0001649=IEP, GO:0009612=IEA, GO:0060348=IEA, GO:0001501=TAS, GO:0002076=IEA, GO:0071363=IEA, GO:0009629=IEA, GO:0005198=NAS, GO:0032571=IEA} bone development, bone mineralization, cell adhesion, cell aging, cellular response to growth factor stimulus, cellular response to vitamin D, odontogenesis, osteoblast development, osteoblast differentiation, regulation of bone mineralization, regulation of bone resorption, regulation of osteoclast differentiation, response to activity, response to drug, response to estrogen stimulus, response to ethanol, response to glucocorticoid stimulus, response to gravity, response to hydroxyisoflavone, response to mechanical stimulus, response to testosterone stimulus, response to vitamin D, response to vitamin K, response to zinc ion, skeletal system development Golgi apparatus, dendrite, extracellular region, extracellular space, membrane-bounded vesicle, perikaryon, rough endoplasmic reticulum calcium ion binding, hydroxyapatite binding, structural constituent of bone, structural molecule activity Human BGN BHF-UCL UniProtKB {GO:0030133=GO_REF:0000054, GO:0019800=GO_REF:0000019, GO:0009986=PMID:2212616, GO:0005975=Reactome:REACT_474, GO:0005796=Reactome:REACT_121341, GO:0050840=GO_REF:0000019, GO:0005578=PMID:1860845, GO:0005576=Reactome:REACT_121341, GO:0044281=Reactome:REACT_111217, GO:0005539=GO_REF:0000019, GO:0030208=Reactome:REACT_120800, GO:0031012=PMID:22261194, GO:0042383=GO_REF:0000019, GO:0030207=Reactome:REACT_120888, GO:0008150=GO_REF:0000015, GO:0030206=Reactome:REACT_120989, GO:0001974=GO_REF:0000019, GO:0044424=GO_REF:0000019, GO:0030204=Reactome:REACT_121206, GO:0030203=Reactome:REACT_121408, GO:0043202=Reactome:REACT_121272, GO:0005201=PMID:1860845} P21810 Biglycan protein 20120228 {GO:0030133=IDA, GO:0019800=IEA, GO:0009986=IDA, GO:0005975=TAS, GO:0005796=TAS, GO:0050840=IEA, GO:0005578=NAS, GO:0005576=TAS, GO:0044281=TAS, GO:0005539=IEA, GO:0030208=TAS, GO:0031012=ISS, GO:0042383=IEA, GO:0030207=TAS, GO:0008150=ND, GO:0030206=TAS, GO:0001974=IEA, GO:0044424=IEA, GO:0030204=TAS, GO:0030203=TAS, GO:0043202=TAS, GO:0005201=NAS} biological_process, blood vessel remodeling, carbohydrate metabolic process, chondroitin sulfate biosynthetic process, chondroitin sulfate catabolic process, chondroitin sulfate metabolic process, dermatan sulfate biosynthetic process, glycosaminoglycan metabolic process, peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan, small molecule metabolic process Golgi lumen, cell surface, extracellular matrix, extracellular region, intracellular part, lysosomal lumen, proteinaceous extracellular matrix, sarcolemma, transport vesicle extracellular matrix binding, extracellular matrix structural constituent, glycosaminoglycan binding colocalizes_with Human UniProtKB:Q9GKQ6 BHLHA15 UniProtKB UniProtKB {GO:0019722=GO_REF:0000019, GO:0048312=GO_REF:0000019, GO:0006851=GO_REF:0000019, GO:0007267=GO_REF:0000019, GO:0005634=GO_REF:0000039, GO:0042593=GO_REF:0000019, GO:0003677=GO_REF:0000019, GO:0006351=GO_REF:0000037, GO:0042803=GO_REF:0000019, GO:0007186=GO_REF:0000019, GO:0045944=GO_REF:0000019, GO:0007030=GO_REF:0000019, GO:0048469=GO_REF:0000019} Q7RTS1 Class A basic helix-loop-helix protein 15 protein 20130413 {GO:0019722=IEA, GO:0048312=IEA, GO:0006851=IEA, GO:0007267=IEA, GO:0005634=IEA, GO:0042593=IEA, GO:0003677=IEA, GO:0006351=IEA, GO:0042803=IEA, GO:0007186=IEA, GO:0045944=IEA, GO:0007030=IEA, GO:0048469=IEA} G-protein coupled receptor signaling pathway, Golgi organization, calcium-mediated signaling, cell maturation, cell-cell signaling, glucose homeostasis, intracellular distribution of mitochondria, mitochondrial calcium ion transport, positive regulation of transcription from RNA polymerase II promoter, transcription, DNA-dependent nucleus DNA binding, protein homodimerization activity Human UniProtKB-SubCell:SL-0191 BHLHB9 UniProtKB UniProtKB {GO:0005737=GO_REF:0000039, GO:0005634=GO_REF:0000039} Q6PI77 Protein BHLHb9 protein 20130413 {GO:0005737=IEA, GO:0005634=IEA} cytoplasm, nucleus Human UniProtKB-SubCell:SL-0086 BHLHE40 GOC UniProtKB {GO:0005515=PMID:11278694, GO:0001191=PMID:18411297, GO:0001102=GO_REF:0000024, GO:0006355=PMID:9240428, GO:0005794=GO_REF:0000052, GO:0003700=PMID:9240428, GO:0006366=PMID:12397359, GO:0046982=PMID:15193144, GO:0003705=GO_REF:0000024, GO:0000981=PMID:12397359, GO:0019904=PMID:15560782, GO:0005730=GO_REF:0000052, GO:0043426=GO_REF:0000024, GO:0043425=PMID:15193144, GO:0005634=GO_REF:0000052, GO:0070888=PMID:15193144, GO:0000122=PMID:12397359, GO:0032922=PMID:18411297, GO:0043433=PMID:18411297, GO:0042803=PMID:15560782, GO:0001078=PMID:15193144, GO:0043153=PMID:18411297} O14503 Class E basic helix-loop-helix protein 40 protein 20130413 {GO:0005515=IPI, GO:0001191=IDA, GO:0001102=ISS, GO:0006355=NAS, GO:0005794=IDA, GO:0003700=NAS, GO:0006366=IDA, GO:0046982=IPI, GO:0003705=ISS, GO:0000981=IDA, GO:0019904=IPI, GO:0005730=IDA, GO:0043426=ISS, GO:0043425=IPI, GO:0005634=IDA, GO:0070888=IDA, GO:0000122=IDA, GO:0032922=IDA, GO:0043433=IDA, GO:0042803=IDA, GO:0001078=IDA, GO:0043153=ISS} circadian regulation of gene expression, entrainment of circadian clock by photoperiod, negative regulation of sequence-specific DNA binding transcription factor activity, negative regulation of transcription from RNA polymerase II promoter, regulation of transcription, DNA-dependent, transcription from RNA polymerase II promoter Golgi apparatus, nucleolus, nucleus E-box binding, MRF binding, RNA polymerase II activating transcription factor binding, RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription, RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity, RNA polymerase II transcription factor binding transcription factor activity involved in negative regulation of transcription, bHLH transcription factor binding, protein binding, protein domain specific binding, protein heterodimerization activity, protein homodimerization activity, sequence-specific DNA binding RNA polymerase II transcription factor activity, sequence-specific DNA binding transcription factor activity Human BHLHE41 BHF-UCL UniProtKB {GO:0001191=GO_REF:0000024, GO:0001102=GO_REF:0000024, GO:0006355=GO_REF:0000029, GO:0003700=GO_REF:0000029, GO:0046982=PMID:15193144, GO:0042826=GO_REF:0000024, GO:0008283=PMID:11162494, GO:0003705=GO_REF:0000024, GO:0043426=GO_REF:0000024, GO:0043425=PMID:15193144, GO:0005634=GO_REF:0000029, GO:0070888=PMID:15193144, GO:0000122=PMID:14672706, GO:0010832=GO_REF:0000024, GO:0000978=GO_REF:0000024, GO:0042803=GO_REF:0000024, GO:0032922=GO_REF:0000019, GO:0030154=PMID:11162494, GO:0001078=GO_REF:0000024, GO:0010944=GO_REF:0000024, GO:0009887=PMID:11162494} Q9C0J9 Class E basic helix-loop-helix protein 41 protein 20120613 {GO:0001191=ISS, GO:0001102=ISS, GO:0006355=NAS, GO:0003700=NAS, GO:0046982=IPI, GO:0042826=ISS, GO:0008283=NAS, GO:0003705=ISS, GO:0043426=ISS, GO:0043425=IPI, GO:0005634=NAS, GO:0070888=IDA, GO:0000122=IDA, GO:0010832=ISS, GO:0000978=ISS, GO:0042803=ISS, GO:0032922=IEA, GO:0030154=NAS, GO:0001078=ISS, GO:0010944=ISS, GO:0009887=NAS} cell differentiation, cell proliferation, circadian regulation of gene expression, negative regulation of myotube differentiation, negative regulation of transcription by competitive promoter binding, negative regulation of transcription from RNA polymerase II promoter, organ morphogenesis, regulation of transcription, DNA-dependent nucleus E-box binding, MRF binding, RNA polymerase II activating transcription factor binding, RNA polymerase II core promoter proximal region sequence-specific DNA binding, RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription, RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity, RNA polymerase II transcription factor binding transcription factor activity involved in negative regulation of transcription, bHLH transcription factor binding, histone deacetylase binding, protein heterodimerization activity, protein homodimerization activity, sequence-specific DNA binding transcription factor activity Human UniProtKB:O14503 BHMT HPA UniProtKB {GO:0009086=GO_REF:0000019, GO:0047150=Reactome:REACT_115861, GO:0044281=Reactome:REACT_111217, GO:0032403=GO_REF:0000019, GO:0050666=PMID:10075673, GO:0005829=Reactome:REACT_115861, GO:0043234=GO_REF:0000019, GO:0034641=Reactome:REACT_13, GO:0005737=GO_REF:0000052, GO:0000096=Reactome:REACT_115639, GO:0006479=PMID:10075673, GO:0008270=GO_REF:0000002, GO:0006579=GO_REF:0000041, GO:0008898=GO_REF:0000002} Q93088 Betaine--homocysteine S-methyltransferase 1 protein 20110516 {GO:0009086=IEA, GO:0047150=TAS, GO:0044281=TAS, GO:0032403=IEA, GO:0050666=NAS, GO:0005829=TAS, GO:0043234=IEA, GO:0034641=TAS, GO:0005737=IDA, GO:0000096=TAS, GO:0006479=NAS, GO:0008270=IEA, GO:0006579=IEA, GO:0008898=IEA} amino-acid betaine catabolic process, cellular nitrogen compound metabolic process, methionine biosynthetic process, protein methylation, regulation of homocysteine metabolic process, small molecule metabolic process, sulfur amino acid metabolic process cytoplasm, cytosol, protein complex betaine-homocysteine S-methyltransferase activity, homocysteine S-methyltransferase activity, protein complex binding, zinc ion binding Human BHMT2 UniPathway UniProtKB {GO:0005737=GO_REF:0000002, GO:0009086=GO_REF:0000002, GO:0047150=GO_REF:0000003, GO:0008270=GO_REF:0000002, GO:0006579=GO_REF:0000041, GO:0008898=GO_REF:0000002} Q9H2M3 S-methylmethionine--homocysteine S-methyltransferase BHMT2 protein 20130413 {GO:0005737=IEA, GO:0009086=IEA, GO:0047150=IEA, GO:0008270=IEA, GO:0006579=IEA, GO:0008898=IEA} amino-acid betaine catabolic process, methionine biosynthetic process cytoplasm betaine-homocysteine S-methyltransferase activity, homocysteine S-methyltransferase activity, zinc ion binding Human UniPathway:UPA00291 BICD1 BHF-UCL UniProtKB {GO:0005515=PMID:20089649, GO:0005802=PMID:20089649, GO:0005881=PMID:20089649, GO:0048471=PMID:20089649, GO:0034452=PMID:12447383, GO:0031871=PMID:20164183, GO:1900737=GO_REF:0000024, GO:0005634=GO_REF:0000002, GO:0072385=PMID:12447383, GO:0009653=PMID:9367685, GO:0005829=PMID:12447383, GO:0006810=GO_REF:0000002, GO:0016032=PMID:20089649, GO:0005856=PMID:9367685, GO:0072517=PMID:20089649, GO:0008093=PMID:12447383, GO:0045298=PMID:20164183, GO:0006396=PMID:9367685, GO:0017137=PMID:12447383, GO:0006355=GO_REF:0000002, GO:0008298=PMID:9367685, GO:0005794=GO_REF:0000039, GO:0033365=PMID:20089649, GO:0031410=PMID:20089649, GO:0003677=GO_REF:0000002, GO:1900275=GO_REF:0000024, GO:0072393=PMID:19825938, GO:1900276=GO_REF:0000024, GO:0034063=GO_REF:0000024, GO:0045502=PMID:12447383, GO:0016020=PMID:12447383, GO:0019048=GO_REF:0000037, GO:0048260=PMID:20164183, GO:0005200=PMID:9367685} Q96G01 Protein bicaudal D homolog 1 protein 20120404 {GO:0005515=IPI, GO:0005802=IDA, GO:0005881=IDA, GO:0048471=IDA, GO:0034452=IDA, GO:0031871=ISS, GO:1900737=ISS, GO:0005634=IEA, GO:0072385=IMP, GO:0009653=TAS, GO:0005829=IDA, GO:0006810=IEA, GO:0016032=IMP, GO:0005856=NAS, GO:0072517=IDA, GO:0008093=IDA, GO:0045298=TAS, GO:0006396=TAS, GO:0017137=IPI, GO:0006355=IEA, GO:0008298=NAS, GO:0005794=IEA, GO:0033365=IDA, GO:0031410=IDA, GO:0003677=IEA, GO:1900275=ISS, GO:0072393=ISS, GO:1900276=ISS, GO:0034063=ISS, GO:0045502=IDA, GO:0016020=IDA, GO:0019048=IEA, GO:0048260=IMP, GO:0005200=TAS} RNA processing, anatomical structure morphogenesis, intracellular mRNA localization, microtubule anchoring at microtubule organizing center, minus-end-directed organelle transport along microtubule, negative regulation of phospholipase C activity, negative regulation of phospholipase C-activating G-protein coupled receptor signaling pathway, positive regulation of receptor-mediated endocytosis, protein localization to organelle, regulation of proteinase activated receptor activity, regulation of transcription, DNA-dependent, stress granule assembly, transport, viral reproduction, virus-host interaction Golgi apparatus, cytoplasmic microtubule, cytoplasmic vesicle, cytoskeleton, cytosol, host cell viral assembly compartment, membrane, nucleus, perinuclear region of cytoplasm, trans-Golgi network, tubulin complex DNA binding, Rab GTPase binding, cytoskeletal adaptor activity, dynactin binding, dynein binding, protein binding, proteinase activated receptor binding, structural constituent of cytoskeleton Human UniProtKB:Q8BR07 BICD2 HPA UniProtKB {GO:0005515=PMID:16417406, GO:0005737=GO_REF:0000052, GO:0017137=GO_REF:0000024, GO:0005794=GO_REF:0000052, GO:0005886=GO_REF:0000052, GO:0031410=GO_REF:0000024, GO:0072385=GO_REF:0000024, GO:0005856=GO_REF:0000039, GO:0072393=GO_REF:0000024} Q8TD16 Protein bicaudal D homolog 2 protein 20101115 {GO:0005515=IPI, GO:0005737=IDA, GO:0017137=ISS, GO:0005794=IDA, GO:0005886=IDA, GO:0031410=ISS, GO:0072385=ISS, GO:0005856=IEA, GO:0072393=ISS} microtubule anchoring at microtubule organizing center, minus-end-directed organelle transport along microtubule Golgi apparatus, cytoplasm, cytoplasmic vesicle, cytoskeleton, plasma membrane Rab GTPase binding, protein binding Human BID BHF-UCL UniProtKB {GO:0005515=PMID:21036904, GO:0008625=PMID:9727491, GO:2001238=PMID:21459798, GO:0006626=GO_REF:0000019, GO:0001836=PMID:17052454, GO:0005741=Reactome:REACT_21389, GO:0051402=PMID:16167175, GO:2000045=GO_REF:0000019, GO:0005829=Reactome:REACT_6160, GO:0005739=PMID:9727491, GO:0008637=PMID:9727492, GO:1900740=Reactome:REACT_701, GO:0042127=GO_REF:0000019, GO:0090200=PMID:21041309, GO:0051260=GO_REF:0000019, GO:0032355=GO_REF:0000019, GO:0031625=GO_REF:0000019, GO:0032464=PMID:21041309, GO:0034349=GO_REF:0000019, GO:0046902=GO_REF:0000019, GO:0043065=PMID:21525171, GO:0090150=PMID:21041309, GO:1901030=Reactome:REACT_707, GO:0006915=Reactome:REACT_578, GO:2001244=Reactome:REACT_330, GO:0005123=PMID:8918887, GO:0097193=Reactome:REACT_964, GO:0016020=PMID:8918887, GO:0032592=GO_REF:0000019, GO:0007420=GO_REF:0000019} P55957 BH3-interacting domain death agonist protein 20110317 {GO:0005515=IPI, GO:0008625=TAS, GO:2001238=IMP, GO:0006626=IEA, GO:0001836=IDA, GO:0005741=TAS, GO:0051402=TAS, GO:2000045=IEA, GO:0005829=TAS, GO:0005739=TAS, GO:0008637=TAS, GO:1900740=TAS, GO:0042127=IEA, GO:0090200=IGI, GO:0051260=IEA, GO:0032355=IEA, GO:0031625=IEA, GO:0032464=IDA, GO:0034349=IEA, GO:0046902=IEA, GO:0043065=IMP, GO:0090150=IDA, GO:1901030=TAS, GO:0006915=TAS, GO:2001244=TAS, GO:0005123=TAS, GO:0097193=TAS, GO:0016020=TAS, GO:0032592=IEA, GO:0007420=IEA} apoptotic mitochondrial changes, apoptotic process, brain development, establishment of protein localization to membrane, extrinsic apoptotic signaling pathway via death domain receptors, glial cell apoptotic process, intrinsic apoptotic signaling pathway, neuron apoptotic process, positive regulation of apoptotic process, positive regulation of extrinsic apoptotic signaling pathway, positive regulation of intrinsic apoptotic signaling pathway, positive regulation of mitochondrial outer membrane permeabilization, positive regulation of protein homooligomerization, positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway, positive regulation of release of cytochrome c from mitochondria, protein homooligomerization, protein targeting to mitochondrion, regulation of G1/S transition of mitotic cell cycle, regulation of cell proliferation, regulation of mitochondrial membrane permeability, release of cytochrome c from mitochondria, response to estradiol stimulus cytosol, integral to mitochondrial membrane, membrane, mitochondrial outer membrane, mitochondrion death receptor binding, protein binding, ubiquitin protein ligase binding Human BIK BHF-UCL UniProtKB {GO:0032464=PMID:21041309, GO:0005515=PMID:17289999, GO:0051400=GO_REF:0000019, GO:0031966=GO_REF:0000039, GO:0046982=GO_REF:0000019, GO:0090200=PMID:21041309, GO:0006915=GO_REF:0000037, GO:0006917=PMID:10381623, GO:0007283=GO_REF:0000019, GO:0016021=GO_REF:0000037, GO:0008584=GO_REF:0000019, GO:0012505=GO_REF:0000039} Q13323 Bcl-2-interacting killer protein 20110317 {GO:0032464=IDA, GO:0005515=IPI, GO:0051400=IEA, GO:0031966=IEA, GO:0046982=IEA, GO:0090200=IDA, GO:0006915=IEA, GO:0006917=TAS, GO:0007283=IEA, GO:0016021=IEA, GO:0008584=IEA, GO:0012505=IEA} apoptotic process, induction of apoptosis, male gonad development, positive regulation of protein homooligomerization, positive regulation of release of cytochrome c from mitochondria, spermatogenesis endomembrane system, integral to membrane, mitochondrial membrane BH domain binding, protein binding, protein heterodimerization activity Human BIN1 HPA UniProtKB {GO:0005515=PMID:16275660, GO:0046982=GO_REF:0000019, GO:0008283=PMID:8782822, GO:0044300=GO_REF:0000019, GO:0005634=GO_REF:0000039, GO:0007275=GO_REF:0000037, GO:0015629=PMID:9182667, GO:0032403=GO_REF:0000019, GO:0006897=GO_REF:0000037, GO:0008021=GO_REF:0000019, GO:0042692=GO_REF:0000019, GO:0043547=GO_REF:0000019, GO:0045807=GO_REF:0000019, GO:0005737=GO_REF:0000052, GO:0051020=GO_REF:0000019, GO:0019048=GO_REF:0000037, GO:0043196=GO_REF:0000019, GO:0043679=GO_REF:0000019} O00499 Myc box-dependent-interacting protein 1 protein 20080205 {GO:0005515=IPI, GO:0046982=IEA, GO:0008283=TAS, GO:0044300=IEA, GO:0005634=IEA, GO:0007275=IEA, GO:0015629=TAS, GO:0032403=IEA, GO:0006897=IEA, GO:0008021=IEA, GO:0042692=IEA, GO:0043547=IEA, GO:0045807=IEA, GO:0005737=IDA, GO:0051020=IEA, GO:0019048=IEA, GO:0043196=IEA, GO:0043679=IEA} cell proliferation, endocytosis, multicellular organismal development, muscle cell differentiation, positive regulation of GTPase activity, positive regulation of endocytosis, virus-host interaction actin cytoskeleton, axon terminus, cerebellar mossy fiber, cytoplasm, nucleus, synaptic vesicle, varicosity GTPase binding, protein binding, protein complex binding, protein heterodimerization activity Human BIN2 IntAct UniProtKB {GO:0005515=PMID:10903846, GO:0071800=PMID:23285027, GO:0005737=GO_REF:0000002, GO:0005543=PMID:23285027, GO:0030054=GO_REF:0000037, GO:0060326=PMID:23285027, GO:0097320=PMID:23285027, GO:0002102=PMID:23285027, GO:0001891=PMID:23285027, GO:0042995=GO_REF:0000037, GO:0006911=PMID:23285027, GO:0005938=GO_REF:0000039} Q9UBW5 Bridging integrator 2 protein 20130415 {GO:0005515=IPI, GO:0071800=IMP, GO:0005737=IEA, GO:0005543=IDA, GO:0030054=IEA, GO:0060326=IMP, GO:0097320=IDA, GO:0002102=IDA, GO:0001891=IDA, GO:0042995=IEA, GO:0006911=IMP, GO:0005938=IEA} cell chemotaxis, membrane tubulation, phagocytosis, engulfment, podosome assembly cell cortex, cell junction, cell projection, cytoplasm, phagocytic cup, podosome phospholipid binding, protein binding Human UniProtKB:O00499 BIN3 IntAct UniProtKB {GO:0005515=PMID:18654987, GO:0000910=PMID:11274158, GO:0007049=GO_REF:0000037, GO:0005737=GO_REF:0000037, GO:0008104=PMID:11274158, GO:0007015=PMID:11274158, GO:0000917=GO_REF:0000037, GO:0005856=GO_REF:0000039, GO:0009826=PMID:11274158, GO:0008093=PMID:11274158} Q9NQY0 Bridging integrator 3 protein 20130415 {GO:0005515=IPI, GO:0000910=NAS, GO:0007049=IEA, GO:0005737=IEA, GO:0008104=IMP, GO:0007015=NAS, GO:0000917=IEA, GO:0005856=IEA, GO:0009826=IMP, GO:0008093=NAS} actin filament organization, barrier septum assembly, cell cycle, cytokinesis, protein localization, unidimensional cell growth cytoplasm, cytoskeleton cytoskeletal adaptor activity, protein binding Human UniProtKB:Q6XZF7 BIRC2 BHF-UCL UniProtKB {GO:0005515=PMID:21988832, GO:0035631=GO_REF:0000024, GO:0004842=PMID:11907583, GO:0034142=Reactome:REACT_6894, GO:0034121=PMID:20888210, GO:0070424=PMID:20888210, GO:0005634=PMID:15665297, GO:0006921=Reactome:REACT_995, GO:0005829=Reactome:REACT_12045, GO:0005622=GO_REF:0000002, GO:0002756=Reactome:REACT_6809, GO:0042127=PMID:18414036, GO:0051726=PMID:15665297, GO:0043123=PMID:12761501, GO:0034138=Reactome:REACT_6783, GO:0000209=PMID:11907583, GO:0006355=GO_REF:0000037, GO:0043066=PMID:21525013, GO:0070266=GO_REF:0000019, GO:0003713=PMID:21653699, GO:0050727=PMID:21447281, GO:0006915=Reactome:REACT_578, GO:0042981=GO_REF:0000019, GO:2000116=PMID:20651737, GO:0001890=GO_REF:0000019, GO:0039535=PMID:20888210, GO:0002224=Reactome:REACT_6966, GO:0006351=GO_REF:0000037, GO:0038061=PMID:20651737, GO:0047485=PMID:19153467, GO:0045087=Reactome:REACT_6802, GO:0045088=PMID:21447281, GO:0009898=GO_REF:0000024, GO:0035666=Reactome:REACT_25281, GO:0043161=PMID:11907583, GO:0008270=PMID:19153467, GO:0045595=PMID:18414036, GO:0007166=PMID:8548810} Q13490 Baculoviral IAP repeat-containing protein 2 protein 20110110 {GO:0005515=IPI, GO:0035631=ISS, GO:0004842=IDA, GO:0034142=TAS, GO:0034121=TAS, GO:0070424=TAS, GO:0005634=IDA, GO:0006921=TAS, GO:0005829=TAS, GO:0005622=IEA, GO:0002756=TAS, GO:0042127=TAS, GO:0051726=IDA, GO:0043123=IEP, GO:0034138=TAS, GO:0000209=IDA, GO:0006355=IEA, GO:0043066=IDA, GO:0070266=IEA, GO:0003713=IMP, GO:0050727=TAS, GO:0006915=TAS, GO:0042981=IEA, GO:2000116=TAS, GO:0001890=IEA, GO:0039535=TAS, GO:0002224=TAS, GO:0006351=IEA, GO:0038061=TAS, GO:0047485=IPI, GO:0045087=TAS, GO:0045088=TAS, GO:0009898=ISS, GO:0035666=TAS, GO:0043161=IDA, GO:0008270=IDA, GO:0045595=TAS, GO:0007166=TAS} MyD88-independent toll-like receptor signaling pathway, NIK/NF-kappaB cascade, TRIF-dependent toll-like receptor signaling pathway, apoptotic process, cell surface receptor signaling pathway, cellular component disassembly involved in execution phase of apoptosis, innate immune response, necroptosis, negative regulation of apoptotic process, placenta development, positive regulation of I-kappaB kinase/NF-kappaB cascade, proteasomal ubiquitin-dependent protein catabolic process, protein polyubiquitination, regulation of RIG-I signaling pathway, regulation of apoptotic process, regulation of cell cycle, regulation of cell differentiation, regulation of cell proliferation, regulation of cysteine-type endopeptidase activity, regulation of inflammatory response, regulation of innate immune response, regulation of nucleotide-binding oligomerization domain containing signaling pathway, regulation of toll-like receptor signaling pathway, regulation of transcription, DNA-dependent, toll-like receptor 3 signaling pathway, toll-like receptor 4 signaling pathway, toll-like receptor signaling pathway, transcription, DNA-dependent CD40 receptor complex, cytosol, internal side of plasma membrane, intracellular, nucleus protein N-terminus binding, protein binding, transcription coactivator activity, ubiquitin-protein ligase activity, zinc ion binding Human UniProtKB:Q62210 BIRC3 IntAct UniProtKB {GO:0005515=PMID:21988832, GO:0004842=PMID:16395405, GO:0034142=Reactome:REACT_6894, GO:0034121=PMID:20888210, GO:0070424=PMID:20888210, GO:0005634=PMID:15665297, GO:0005829=Reactome:REACT_6884, GO:0005622=GO_REF:0000002, GO:0002756=Reactome:REACT_6809, GO:0005737=PMID:15665297, GO:0043123=PMID:20651737, GO:0034138=Reactome:REACT_6783, GO:0060546=GO_REF:0000019, GO:0043066=PMID:8552191, GO:0070266=GO_REF:0000019, GO:0050727=PMID:21447281, GO:0006915=GO_REF:0000037, GO:0042981=GO_REF:0000002, GO:2000116=PMID:20651737, GO:0039535=PMID:20888210, GO:0002224=Reactome:REACT_6966, GO:0038061=PMID:20651737, GO:0042326=GO_REF:0000019, GO:0045087=Reactome:REACT_6802, GO:0045088=PMID:21447281, GO:0035666=Reactome:REACT_25281, GO:0008270=GO_REF:0000002, GO:2000378=GO_REF:0000019, GO:0007166=PMID:8548810} Q13489 Baculoviral IAP repeat-containing protein 3 protein 20130415 {GO:0005515=IPI, GO:0004842=IDA, GO:0034142=TAS, GO:0034121=TAS, GO:0070424=TAS, GO:0005634=IDA, GO:0005829=TAS, GO:0005622=IEA, GO:0002756=TAS, GO:0005737=IDA, GO:0043123=TAS, GO:0034138=TAS, GO:0060546=IEA, GO:0043066=TAS, GO:0070266=IEA, GO:0050727=TAS, GO:0006915=IEA, GO:0042981=IEA, GO:2000116=TAS, GO:0039535=TAS, GO:0002224=TAS, GO:0038061=TAS, GO:0042326=IEA, GO:0045087=TAS, GO:0045088=TAS, GO:0035666=TAS, GO:0008270=IEA, GO:2000378=IEA, GO:0007166=TAS} MyD88-independent toll-like receptor signaling pathway, NIK/NF-kappaB cascade, TRIF-dependent toll-like receptor signaling pathway, apoptotic process, cell surface receptor signaling pathway, innate immune response, necroptosis, negative regulation of apoptotic process, negative regulation of necroptosis, negative regulation of phosphorylation, negative regulation of reactive oxygen species metabolic process, positive regulation of I-kappaB kinase/NF-kappaB cascade, regulation of RIG-I signaling pathway, regulation of apoptotic process, regulation of cysteine-type endopeptidase activity, regulation of inflammatory response, regulation of innate immune response, regulation of nucleotide-binding oligomerization domain containing signaling pathway, regulation of toll-like receptor signaling pathway, toll-like receptor 3 signaling pathway, toll-like receptor 4 signaling pathway, toll-like receptor signaling pathway cytoplasm, cytosol, intracellular, nucleus protein binding, ubiquitin-protein ligase activity, zinc ion binding Human UniProtKB:Q12933 BIRC5 LIFEdb UniProtKB {GO:0008017=PMID:21536684, GO:0005515=PMID:18243099, GO:0000236=Reactome:REACT_682, GO:0008284=PMID:16344111, GO:0004869=GO_REF:0000037, GO:0031503=PMID:16239925, GO:0051087=PMID:18086682, GO:0005634=PMID:20826784, GO:0009790=GO_REF:0000019, GO:0046872=GO_REF:0000037, GO:0005829=Reactome:REACT_150414, GO:0005737=GO_REF:0000054, GO:0043524=GO_REF:0000019, GO:0007059=GO_REF:0000037, GO:0000087=Reactome:REACT_910, GO:0008536=PMID:18591255, GO:0005874=GO_REF:0000037, GO:0005819=GO_REF:0000039, GO:0006915=GO_REF:0000037, GO:0000226=GO_REF:0000019, GO:0030496=PMID:11084331, GO:0042981=PMID:21536684, GO:0000228=PMID:16322459, GO:0006351=GO_REF:0000037, GO:0032133=PMID:18591255, GO:0000777=PMID:15665297, GO:0006468=PMID:21252625, GO:0000278=Reactome:REACT_152, GO:0019899=PMID:16322459, GO:0000090=Reactome:REACT_1275, GO:0045892=PMID:20826784, GO:0000775=PMID:11084331, GO:0051301=GO_REF:0000037} O15392 Baculoviral IAP repeat-containing protein 5 protein 20100607 {GO:0008017=TAS, GO:0005515=IPI, GO:0000236=TAS, GO:0008284=TAS, GO:0004869=IEA, GO:0031503=IMP, GO:0051087=IPI, GO:0005634=IDA, GO:0009790=IEA, GO:0046872=IEA, GO:0005829=TAS, GO:0005737=IDA, GO:0043524=IEA, GO:0007059=IEA, GO:0000087=TAS, GO:0008536=IPI, GO:0005874=IEA, GO:0005819=IEA, GO:0006915=IEA, GO:0000226=IEA, GO:0030496=IDA, GO:0042981=IMP, GO:0000228=IDA, GO:0006351=IEA, GO:0032133=IPI, GO:0000777=IDA, GO:0006468=IDA, GO:0000278=TAS, GO:0019899=IPI, GO:0000090=TAS, GO:0045892=IMP, GO:0000775=IDA, GO:0051301=IEA} M phase of mitotic cell cycle, apoptotic process, cell division, chromosome segregation, embryo development, microtubule cytoskeleton organization, mitotic anaphase, mitotic cell cycle, mitotic prometaphase, negative regulation of neuron apoptotic process, negative regulation of transcription, DNA-dependent, positive regulation of cell proliferation, protein complex localization, protein phosphorylation, regulation of apoptotic process, transcription, DNA-dependent chromosome passenger complex, chromosome, centromeric region, condensed chromosome kinetochore, cytoplasm, cytosol, microtubule, midbody, nuclear chromosome, nucleus, spindle Ran GTPase binding, chaperone binding, cysteine-type endopeptidase inhibitor activity, enzyme binding, metal ion binding, microtubule binding, protein binding Human BIRC6 IntAct UniProtKB {GO:0005802=PMID:18329369, GO:0005515=PMID:18329369, GO:0008284=GO_REF:0000019, GO:0060711=GO_REF:0000019, GO:0043066=PMID:15200957, GO:0004842=PMID:15200957, GO:0016567=PMID:18329369, GO:0032465=PMID:18329369, GO:0004869=PMID:15200957, GO:0005794=GO_REF:0000039, GO:0005815=PMID:18329369, GO:0060712=GO_REF:0000019, GO:0030496=PMID:18329369, GO:0006915=GO_REF:0000037, GO:0005575=GO_REF:0000015, GO:0000922=PMID:18329369, GO:0007067=GO_REF:0000037, GO:0016020=GO_REF:0000019, GO:0042127=PMID:18414036, GO:0006468=PMID:18329369, GO:0005768=PMID:18329369, GO:0051301=GO_REF:0000037} Q9NR09 Baculoviral IAP repeat-containing protein 6 protein 20130415 {GO:0005802=IDA, GO:0005515=IPI, GO:0008284=IEA, GO:0060711=IEA, GO:0043066=IMP, GO:0004842=IDA, GO:0016567=TAS, GO:0032465=IMP, GO:0004869=IMP, GO:0005794=IEA, GO:0005815=IDA, GO:0060712=IEA, GO:0030496=IDA, GO:0006915=IEA, GO:0005575=ND, GO:0000922=IDA, GO:0007067=IEA, GO:0016020=IEA, GO:0042127=TAS, GO:0006468=TAS, GO:0005768=IDA, GO:0051301=IEA} apoptotic process, cell division, labyrinthine layer development, mitosis, negative regulation of apoptotic process, positive regulation of cell proliferation, protein phosphorylation, protein ubiquitination, regulation of cell proliferation, regulation of cytokinesis, spongiotrophoblast layer development Golgi apparatus, cellular_component, endosome, membrane, microtubule organizing center, midbody, spindle pole, trans-Golgi network cysteine-type endopeptidase inhibitor activity, protein binding, ubiquitin-protein ligase activity Human UniProtKB:Q02750 BIRC7 IntAct UniProtKB {GO:0005515=PMID:11801603, GO:0043066=PMID:16729033, GO:0004842=PMID:16729033, GO:0016567=PMID:16729033, GO:0005794=PMID:17294084, GO:0004869=PMID:21617971, GO:0005634=PMID:17294084, GO:0070247=PMID:18034418, GO:0007257=PMID:11865055, GO:0005737=PMID:17294084, GO:0006309=PMID:11024045, GO:0042127=PMID:21617971, GO:0008270=GO_REF:0000002, GO:0019899=PMID:11801603} Q96CA5 Baculoviral IAP repeat-containing protein 7 protein 20130415 {GO:0005515=IPI, GO:0043066=IMP, GO:0004842=IDA, GO:0016567=IDA, GO:0005794=IDA, GO:0004869=TAS, GO:0005634=IDA, GO:0070247=IDA, GO:0007257=NAS, GO:0005737=IDA, GO:0006309=NAS, GO:0042127=IDA, GO:0008270=IEA, GO:0019899=NAS} activation of JUN kinase activity, apoptotic DNA fragmentation, negative regulation of apoptotic process, protein ubiquitination, regulation of cell proliferation, regulation of natural killer cell apoptotic process Golgi apparatus, cytoplasm, nucleus cysteine-type endopeptidase inhibitor activity, enzyme binding, protein binding, ubiquitin-protein ligase activity, zinc ion binding Human UniProtKB:Q9NR28 BIRC8 ENSEMBL UniProtKB {GO:0043234=GO_REF:0000019, GO:0048471=GO_REF:0000019, GO:0043524=GO_REF:0000019, GO:0097110=GO_REF:0000019, GO:0005634=GO_REF:0000019, GO:0008270=GO_REF:0000002, GO:0043154=GO_REF:0000019, GO:0002020=GO_REF:0000019, GO:0005829=GO_REF:0000019} Q96P09 Baculoviral IAP repeat-containing protein 8 protein 20130413 {GO:0043234=IEA, GO:0048471=IEA, GO:0043524=IEA, GO:0097110=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0043154=IEA, GO:0002020=IEA, GO:0005829=IEA} negative regulation of cysteine-type endopeptidase activity involved in apoptotic process, negative regulation of neuron apoptotic process cytosol, nucleus, perinuclear region of cytoplasm, protein complex protease binding, scaffold protein binding, zinc ion binding Human Ensembl:ENSRNOP00000009336 BIVM UniProtKB UniProtKB {GO:0005737=GO_REF:0000039, GO:0005634=GO_REF:0000039} Q86UB2 Basic immunoglobulin-like variable motif-containing protein protein 20130413 {GO:0005737=IEA, GO:0005634=IEA} cytoplasm, nucleus Human UniProtKB-SubCell:SL-0086 BLCAP IntAct UniProtKB {GO:0005515=PMID:21217774, GO:0007049=GO_REF:0000037, GO:0006915=PMID:17031575, GO:0016021=GO_REF:0000037} P62952 Bladder cancer-associated protein protein 20130415 {GO:0005515=IPI, GO:0007049=IEA, GO:0006915=IDA, GO:0016021=IEA} apoptotic process, cell cycle integral to membrane protein binding Human UniProtKB:P03372 BLID UniProtKB UniProtKB {GO:0005739=GO_REF:0000039, GO:0006915=GO_REF:0000037} Q8IZY5 BH3-like motif-containing cell death inducer protein 20130413 {GO:0005739=IEA, GO:0006915=IEA} apoptotic process mitochondrion Human UniProtKB-SubCell:SL-0173 BLK PINC UniProtKB {GO:0050853=PMID:876631, GO:0004672=GO_REF:0000002, GO:0005886=GO_REF:0000039, GO:0032024=PMID:19667185, GO:0004713=PMID:7845672, GO:0004715=PMID:876631, GO:0005524=GO_REF:0000037, GO:0007243=PMID:2404338} P51451 Tyrosine-protein kinase Blk protein 20030904 {GO:0050853=IDA, GO:0004672=IEA, GO:0005886=IEA, GO:0032024=IMP, GO:0004713=TAS, GO:0004715=IDA, GO:0005524=IEA, GO:0007243=TAS} B cell receptor signaling pathway, intracellular protein kinase cascade, positive regulation of insulin secretion plasma membrane ATP binding, non-membrane spanning protein tyrosine kinase activity, protein kinase activity, protein tyrosine kinase activity Human BLM GOC UniProtKB {GO:0005515=PMID:16030011, GO:0006200=PMID:17878217, GO:0010165=PMID:11309417, GO:0048478=PMID:10779560, GO:0005657=GO_REF:0000019, GO:0046632=GO_REF:0000019, GO:0031572=PMID:11309417, GO:0005634=GO_REF:0000052, GO:0000079=PMID:15604258, GO:0051259=PMID:10359700, GO:0016363=PMID:11309417, GO:0000085=PMID:11309417, GO:0002039=PMID:11781842, GO:0005737=GO_REF:0000052, GO:0004003=PMID:21325134, GO:0000723=GO_REF:0000019, GO:0003697=PMID:12818200, GO:0000724=PMID:11309417, GO:0046641=GO_REF:0000019, GO:0051782=PMID:11781842, GO:0016887=PMID:17878217, GO:0000729=PMID:21325134, GO:0008026=PMID:12818200, GO:0000781=PMID:10779560, GO:0043140=GO_REF:0000019, GO:0000405=PMID:11433031, GO:0005730=PMID:10779560, GO:0004386=PMID:17878217, GO:0051880=PMID:11433031, GO:0006310=PMID:7585968, GO:0051098=GO_REF:0000019, GO:0000800=PMID:10728666, GO:0005524=PMID:17878217, GO:0003677=GO_REF:0000002, GO:0006974=PMID:12818200, GO:0006260=GO_REF:0000002, GO:0000733=PMID:17878217, GO:0036310=PMID:17878217, GO:0045950=GO_REF:0000019, GO:0006281=PMID:7585968, GO:0009378=PMID:11433031, GO:0016605=PMID:10728666, GO:0031297=PMID:17115688, GO:0045120=GO_REF:0000019, GO:0045893=PMID:11781842, GO:0001673=GO_REF:0000019, GO:0045910=PMID:9671747} P54132 Bloom syndrome protein protein 20130413 {GO:0005515=IPI, GO:0006200=IDA, GO:0010165=IDA, GO:0048478=NAS, GO:0005657=IEA, GO:0046632=IEA, GO:0031572=NAS, GO:0005634=IDA, GO:0000079=IMP, GO:0051259=IDA, GO:0016363=IDA, GO:0000085=NAS, GO:0002039=IPI, GO:0005737=IDA, GO:0004003=IMP, GO:0000723=IEA, GO:0003697=IDA, GO:0000724=NAS, GO:0046641=IEA, GO:0051782=IMP, GO:0016887=IDA, GO:0000729=IDA, GO:0008026=IDA, GO:0000781=IDA, GO:0043140=IEA, GO:0000405=IDA, GO:0005730=IDA, GO:0004386=IDA, GO:0051880=IDA, GO:0006310=NAS, GO:0051098=IEA, GO:0000800=IDA, GO:0005524=IDA, GO:0003677=IEA, GO:0006974=IMP, GO:0006260=IEA, GO:0000733=IDA, GO:0036310=IDA, GO:0045950=IEA, GO:0006281=NAS, GO:0009378=IDA, GO:0016605=IDA, GO:0031297=IDA, GO:0045120=IEA, GO:0045893=IDA, GO:0001673=IEA, GO:0045910=IMP} ATP catabolic process, DNA double-strand break processing, DNA recombination, DNA repair, DNA replication, DNA strand renaturation, G2 DNA damage checkpoint, G2 phase of mitotic cell cycle, alpha-beta T cell differentiation, double-strand break repair via homologous recombination, negative regulation of DNA recombination, negative regulation of cell division, negative regulation of mitotic recombination, positive regulation of alpha-beta T cell proliferation, positive regulation of transcription, DNA-dependent, protein oligomerization, regulation of binding, regulation of cyclin-dependent protein serine/threonine kinase activity, replication fork processing, replication fork protection, response to DNA damage stimulus, response to X-ray, telomere maintenance PML body, chromosome, telomeric region, cytoplasm, lateral element, male germ cell nucleus, nuclear matrix, nucleolus, nucleus, pronucleus, replication fork ATP binding, ATP-dependent 3'-5' DNA helicase activity, ATP-dependent DNA helicase activity, ATP-dependent helicase activity, ATPase activity, DNA binding, G-quadruplex DNA binding, annealing helicase activity, bubble DNA binding, four-way junction helicase activity, helicase activity, p53 binding, protein binding, single-stranded DNA binding Human BLMH HPA UniProtKB {GO:0000209=Reactome:REACT_75842, GO:0005515=PMID:11350084, GO:0002474=Reactome:REACT_75820, GO:0042493=GO_REF:0000019, GO:0009636=GO_REF:0000019, GO:0005634=GO_REF:0000052, GO:0005829=Reactome:REACT_75931, GO:0004197=GO_REF:0000002, GO:0005737=GO_REF:0000052, GO:0004177=PMID:9546396, GO:0006508=GO_REF:0000037, GO:0004180=PMID:9546396, GO:0008234=PMID:8639621} Q13867 Bleomycin hydrolase protein 20110516 {GO:0000209=TAS, GO:0005515=IPI, GO:0002474=TAS, GO:0042493=IEA, GO:0009636=IEA, GO:0005634=IDA, GO:0005829=TAS, GO:0004197=IEA, GO:0005737=IDA, GO:0004177=TAS, GO:0006508=IEA, GO:0004180=TAS, GO:0008234=TAS} antigen processing and presentation of peptide antigen via MHC class I, protein polyubiquitination, proteolysis, response to drug, response to toxic substance cytoplasm, cytosol, nucleus aminopeptidase activity, carboxypeptidase activity, cysteine-type endopeptidase activity, cysteine-type peptidase activity, protein binding Human BLNK GOC UniProtKB {GO:0005515=PMID:21930792, GO:0005622=PMID:9341187, GO:0035556=PMID:9341187, GO:0006954=PMID:9697839, GO:0005886=Reactome:REACT_118834, GO:0006959=PMID:9697839, GO:0005070=PMID:19641626, GO:0030183=PMID:10583958, GO:0005068=PMID:9697839, GO:0007169=PMID:9697839, GO:0005829=Reactome:REACT_118834} Q8WV28 B-cell linker protein protein 20130413 {GO:0005515=IPI, GO:0005622=NAS, GO:0035556=IDA, GO:0006954=TAS, GO:0005886=TAS, GO:0006959=TAS, GO:0005070=RCA, GO:0030183=NAS, GO:0005068=TAS, GO:0007169=TAS, GO:0005829=TAS} B cell differentiation, humoral immune response, inflammatory response, intracellular signal transduction, transmembrane receptor protein tyrosine kinase signaling pathway cytosol, intracellular, plasma membrane SH3/SH2 adaptor activity, protein binding, transmembrane receptor protein tyrosine kinase adaptor activity Human BLOC1S1 IntAct UniProtKB {GO:0005515=PMID:22309213, GO:0048490=GO_REF:0000024, GO:0032438=PMID:22203680, GO:0006892=Reactome:REACT_11235, GO:0005765=Reactome:REACT_19390, GO:0018394=PMID:22309213, GO:0031175=GO_REF:0000024, GO:0005829=PMID:22309213, GO:0009060=PMID:22309213, GO:0005758=PMID:22309213, GO:0031083=PMID:22203680, GO:0005759=PMID:22309213, GO:0060155=PMID:15102850, GO:0008089=GO_REF:0000024, GO:0016044=Reactome:REACT_11123} P78537 Biogenesis of lysosome-related organelles complex 1 subunit 1 protein 20130415 {GO:0005515=IPI, GO:0048490=ISS, GO:0032438=NAS, GO:0006892=TAS, GO:0005765=TAS, GO:0018394=IMP, GO:0031175=ISS, GO:0005829=IDA, GO:0009060=IMP, GO:0005758=IDA, GO:0031083=IDA, GO:0005759=IDA, GO:0060155=NAS, GO:0008089=ISS, GO:0016044=TAS} aerobic respiration, anterograde axon cargo transport, anterograde synaptic vesicle transport, cellular membrane organization, melanosome organization, neuron projection development, peptidyl-lysine acetylation, platelet dense granule organization, post-Golgi vesicle-mediated transport BLOC-1 complex, cytosol, lysosomal membrane, mitochondrial intermembrane space, mitochondrial matrix protein binding Human UniProtKB:Q16795 BLOC1S2 IntAct UniProtKB {GO:0005515=PMID:18188704, GO:0005813=GO_REF:0000019, GO:0048490=GO_REF:0000024, GO:0043015=PMID:15381421, GO:0032438=PMID:22203680, GO:0005634=GO_REF:0000019, GO:0042981=PMID:18188704, GO:0008022=GO_REF:0000019, GO:0031175=GO_REF:0000024, GO:0031083=PMID:22203680, GO:0045944=GO_REF:0000033, GO:0000930=PMID:15381421, GO:0060155=PMID:15102850, GO:0008089=GO_REF:0000024, GO:0055037=GO_REF:0000019} Q6QNY1 Biogenesis of lysosome-related organelles complex 1 subunit 2 protein 20130415 {GO:0005515=IPI, GO:0005813=IEA, GO:0048490=ISS, GO:0043015=IDA, GO:0032438=NAS, GO:0005634=IEA, GO:0042981=IMP, GO:0008022=IEA, GO:0031175=ISS, GO:0031083=IDA, GO:0045944=IBA, GO:0000930=IDA, GO:0060155=NAS, GO:0008089=ISS, GO:0055037=IEA} anterograde axon cargo transport, anterograde synaptic vesicle transport, melanosome organization, neuron projection development, platelet dense granule organization, positive regulation of transcription from RNA polymerase II promoter, regulation of apoptotic process BLOC-1 complex, centrosome, gamma-tubulin complex, nucleus, recycling endosome gamma-tubulin binding, protein C-terminus binding, protein binding Human UniProtKB:Q9NWB7 BLOC1S3 Reactome UniProtKB {GO:0030133=PMID:17182842, GO:0048490=GO_REF:0000024, GO:0042493=GO_REF:0000019, GO:0032438=PMID:22203680, GO:0001654=PMID:16385460, GO:0006892=Reactome:REACT_11235, GO:0030168=PMID:16385460, GO:0032402=PMID:17182842, GO:0031175=GO_REF:0000024, GO:0005829=Reactome:REACT_19390, GO:0032816=GO_REF:0000019, GO:0003674=GO_REF:0000015, GO:0031083=PMID:22203680, GO:0033299=GO_REF:0000019, GO:0035646=PMID:17182842, GO:0043473=PMID:16385460, GO:0060155=PMID:15102850, GO:0008089=GO_REF:0000024, GO:0016044=Reactome:REACT_11123} Q6QNY0 Biogenesis of lysosome-related organelles complex 1 subunit 3 protein 20090721 {GO:0030133=IDA, GO:0048490=ISS, GO:0042493=IEA, GO:0032438=NAS, GO:0001654=IMP, GO:0006892=TAS, GO:0030168=IMP, GO:0032402=IDA, GO:0031175=ISS, GO:0005829=TAS, GO:0032816=IEA, GO:0003674=ND, GO:0031083=IDA, GO:0033299=IEA, GO:0035646=IDA, GO:0043473=IMP, GO:0060155=NAS, GO:0008089=ISS, GO:0016044=TAS} anterograde axon cargo transport, anterograde synaptic vesicle transport, cellular membrane organization, endosome to melanosome transport, eye development, melanosome organization, melanosome transport, neuron projection development, pigmentation, platelet activation, platelet dense granule organization, positive regulation of natural killer cell activation, post-Golgi vesicle-mediated transport, response to drug, secretion of lysosomal enzymes BLOC-1 complex, cytosol, transport vesicle molecular_function Human BLVRA Reactome UniProtKB {GO:0006778=Reactome:REACT_9431, GO:0004074=PMID:10858451, GO:0016491=GO_REF:0000002, GO:0008270=GO_REF:0000002, GO:0044281=Reactome:REACT_111217, GO:0042167=Reactome:REACT_22297, GO:0005829=Reactome:REACT_22177, GO:0055114=PMID:10858451} P53004 Biliverdin reductase A protein 20061120 {GO:0006778=TAS, GO:0004074=IDA, GO:0016491=IEA, GO:0008270=IEA, GO:0044281=TAS, GO:0042167=TAS, GO:0005829=TAS, GO:0055114=IDA} heme catabolic process, oxidation-reduction process, porphyrin-containing compound metabolic process, small molecule metabolic process cytosol biliverdin reductase activity, oxidoreductase activity, zinc ion binding Human BLVRB HPA UniProtKB {GO:0005737=GO_REF:0000052, GO:0005886=GO_REF:0000052, GO:0006778=Reactome:REACT_9431, GO:0042602=PMID:11224564, GO:0004074=PMID:7929092, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0044281=Reactome:REACT_111217, GO:0042167=Reactome:REACT_22297, GO:0005829=Reactome:REACT_22177} P30043 Flavin reductase (NADPH) protein 20120912 {GO:0005737=IDA, GO:0005886=IDA, GO:0006778=TAS, GO:0042602=IDA, GO:0004074=IDA, GO:0005730=IDA, GO:0005634=IDA, GO:0044281=TAS, GO:0042167=TAS, GO:0005829=TAS} heme catabolic process, porphyrin-containing compound metabolic process, small molecule metabolic process cytoplasm, cytosol, nucleolus, nucleus, plasma membrane biliverdin reductase activity, riboflavin reductase (NADPH) activity Human BLZF1 HPA UniProtKB {GO:0003700=PMID:9129147, GO:0006357=PMID:9129147, GO:0008283=PMID:9129147, GO:0043001=PMID:11739401, GO:0005796=GO_REF:0000039, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0001558=PMID:9129147, GO:0003677=PMID:9129147, GO:0005737=PMID:11056056, GO:0000088=Reactome:REACT_765, GO:0000139=Reactome:REACT_147850, GO:0000087=Reactome:REACT_910, GO:0007030=PMID:11739401, GO:0000278=Reactome:REACT_152, GO:0019899=PMID:21478859, GO:0031625=PMID:21478859} Q9H2G9 Golgin-45 protein 20100326 {GO:0003700=NAS, GO:0006357=TAS, GO:0008283=TAS, GO:0043001=IDA, GO:0005796=IEA, GO:0005730=IDA, GO:0005634=IDA, GO:0001558=NAS, GO:0003677=NAS, GO:0005737=NAS, GO:0000088=TAS, GO:0000139=TAS, GO:0000087=TAS, GO:0007030=IDA, GO:0000278=TAS, GO:0019899=IPI, GO:0031625=IPI} Golgi organization, Golgi to plasma membrane protein transport, M phase of mitotic cell cycle, cell proliferation, mitotic cell cycle, mitotic prophase, regulation of cell growth, regulation of transcription from RNA polymerase II promoter Golgi lumen, Golgi membrane, cytoplasm, nucleolus, nucleus DNA binding, enzyme binding, sequence-specific DNA binding transcription factor activity, ubiquitin protein ligase binding NOT Human BMF BHF-UCL UniProtKB {GO:0005515=PMID:11546872, GO:0032464=GO_REF:0000024, GO:1900740=Reactome:REACT_2100, GO:0005886=Reactome:REACT_1981, GO:0001669=GO_REF:0000019, GO:0090200=GO_REF:0000024, GO:0006915=Reactome:REACT_578, GO:2001244=Reactome:REACT_330, GO:0005741=Reactome:REACT_21389, GO:0016459=PMID:11546872, GO:0097193=Reactome:REACT_964, GO:0005829=Reactome:REACT_1981} Q96LC9 Bcl-2-modifying factor protein 20110317 {GO:0005515=IPI, GO:0032464=ISS, GO:1900740=TAS, GO:0005886=TAS, GO:0001669=IEA, GO:0090200=ISS, GO:0006915=TAS, GO:2001244=TAS, GO:0005741=TAS, GO:0016459=ISS, GO:0097193=TAS, GO:0005829=TAS} apoptotic process, intrinsic apoptotic signaling pathway, positive regulation of intrinsic apoptotic signaling pathway, positive regulation of protein homooligomerization, positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway, positive regulation of release of cytochrome c from mitochondria acrosomal vesicle, cytosol, mitochondrial outer membrane, myosin complex, plasma membrane protein binding Human UniProtKB:Q91ZE9 BMI1 ENSEMBL UniProtKB {GO:0010468=PMID:17420273, GO:0005515=PMID:22897849, GO:0048103=GO_REF:0000019, GO:0004842=GO_REF:0000019, GO:0030890=GO_REF:0000019, GO:0000151=GO_REF:0000019, GO:0048704=GO_REF:0000019, GO:0005634=GO_REF:0000052, GO:0048146=PMID:17420273, GO:0005737=GO_REF:0000039, GO:0006959=GO_REF:0000019, GO:0051443=PMID:16714294, GO:0071535=PMID:16714294, GO:0021903=GO_REF:0000019, GO:0031519=GO_REF:0000019, GO:0030097=PMID:15334543, GO:0035102=PMID:19636380, GO:0043066=GO_REF:0000019, GO:0007379=PMID:7715727, GO:0016573=GO_REF:0000019, GO:0016574=GO_REF:0000019, GO:0005730=GO_REF:0000052, GO:0000122=GO_REF:0000019, GO:0001701=GO_REF:0000019, GO:0006351=GO_REF:0000037, GO:0033092=GO_REF:0000019, GO:0043565=GO_REF:0000019, GO:0016604=GO_REF:0000019, GO:0007420=GO_REF:0000019, GO:0003682=GO_REF:0000019, GO:0008270=GO_REF:0000002} Q5T8Z6 Polycomb complex protein BMI-1 protein 20130413 {GO:0010468=IMP, GO:0005515=IPI, GO:0048103=IEA, GO:0004842=IEA, GO:0030890=IEA, GO:0000151=IEA, GO:0048704=IEA, GO:0005634=IDA, GO:0048146=IMP, GO:0005737=IEA, GO:0006959=IEA, GO:0051443=IDA, GO:0071535=IPI, GO:0021903=IEA, GO:0031519=IEA, GO:0030097=IEP, GO:0035102=IDA, GO:0043066=IEA, GO:0007379=TAS, GO:0016573=IEA, GO:0016574=IEA, GO:0005730=IDA, GO:0000122=IEA, GO:0001701=IEA, GO:0006351=IEA, GO:0033092=IEA, GO:0043565=IEA, GO:0016604=IEA, GO:0007420=IEA, GO:0003682=IEA, GO:0008270=IEA} brain development, embryonic skeletal system morphogenesis, hemopoiesis, histone acetylation, histone ubiquitination, humoral immune response, in utero embryonic development, negative regulation of apoptotic process, negative regulation of transcription from RNA polymerase II promoter, positive regulation of B cell proliferation, positive regulation of fibroblast proliferation, positive regulation of immature T cell proliferation in thymus, positive regulation of ubiquitin-protein ligase activity, regulation of gene expression, rostrocaudal neural tube patterning, segment specification, somatic stem cell division, transcription, DNA-dependent PRC1 complex, PcG protein complex, cytoplasm, nuclear body, nucleolus, nucleus, ubiquitin ligase complex RING-like zinc finger domain binding, chromatin binding, protein binding, sequence-specific DNA binding, ubiquitin-protein ligase activity, zinc ion binding Human Ensembl:ENSMUSP00000028071 BMP1 UniProtKB UniProtKB {GO:0006629=Reactome:REACT_602, GO:0005794=GO_REF:0000039, GO:0005509=GO_REF:0000002, GO:0005578=GO_REF:0000039, GO:0005576=Reactome:REACT_150462, GO:0007275=PMID:7798260, GO:0044281=Reactome:REACT_111217, GO:0005125=GO_REF:0000037, GO:0005615=GO_REF:0000037, GO:0030154=GO_REF:0000037, GO:0001501=PMID:7798260, GO:0001503=GO_REF:0000037, GO:0030198=Reactome:REACT_118779, GO:0001502=PMID:3201241, GO:0042157=Reactome:REACT_13621, GO:0061036=PMID:3201241, GO:0006508=GO_REF:0000038, GO:0008270=GO_REF:0000002, GO:0008233=PMID:12393877, GO:0004222=GO_REF:0000002, GO:0008083=GO_REF:0000037, GO:0008237=PMID:7798260} Q3MIM8 Bone morphogenetic protein 1 protein 20130413 {GO:0006629=TAS, GO:0005794=IEA, GO:0005509=IEA, GO:0005578=IEA, GO:0005576=TAS, GO:0007275=TAS, GO:0044281=TAS, GO:0005125=IEA, GO:0005615=IEA, GO:0030154=IEA, GO:0001501=NAS, GO:0001503=IEA, GO:0030198=TAS, GO:0001502=TAS, GO:0042157=TAS, GO:0061036=IDA, GO:0006508=IEA, GO:0008270=IEA, GO:0008233=IDA, GO:0004222=IEA, GO:0008083=IEA, GO:0008237=NAS} cartilage condensation, cell differentiation, extracellular matrix organization, lipid metabolic process, lipoprotein metabolic process, multicellular organismal development, ossification, positive regulation of cartilage development, proteolysis, skeletal system development, small molecule metabolic process Golgi apparatus, extracellular region, extracellular space, proteinaceous extracellular matrix calcium ion binding, cytokine activity, growth factor activity, metalloendopeptidase activity, metallopeptidase activity, peptidase activity, zinc ion binding Human UniProtKB-KW:KW-0645 BMP10 BHF-UCL UniProtKB {GO:0005515=PMID:17068149, GO:0060045=PMID:10072785, GO:0030018=PMID:17921333, GO:0030308=PMID:17068149, GO:0055010=PMID:10072785, GO:0005615=PMID:17921333, GO:0007512=PMID:10072785, GO:0010614=GO_REF:0000024, GO:0030198=Reactome:REACT_118779, GO:0014898=PMID:17921333, GO:0010613=PMID:17921333, GO:0033612=PMID:17068149, GO:0055009=PMID:10072785, GO:0030336=PMID:17068149, GO:0009986=PMID:17921333, GO:0010862=PMID:16049014, GO:0045214=GO_REF:0000024, GO:0005576=Reactome:REACT_150165, GO:0030509=PMID:17068149, GO:0032924=PMID:17068149, GO:0005125=GO_REF:0000037, GO:2000138=GO_REF:0000024, GO:0060038=GO_REF:0000024, GO:0060347=GO_REF:0000024, GO:0010596=PMID:17068149, GO:0055117=PMID:17921333, GO:0055015=PMID:10072785, GO:0060389=PMID:17068149, GO:0045893=PMID:17068149, GO:0008083=GO_REF:0000037} O95393 Bone morphogenetic protein 10 protein 20120927 {GO:0005515=IPI, GO:0060045=ISS, GO:0030018=IDA, GO:0030308=IDA, GO:0055010=ISS, GO:0005615=IDA, GO:0007512=ISS, GO:0010614=ISS, GO:0030198=TAS, GO:0014898=IC, GO:0010613=IMP, GO:0033612=IDA, GO:0055009=ISS, GO:0030336=IDA, GO:0009986=IDA, GO:0010862=IDA, GO:0045214=ISS, GO:0005576=TAS, GO:0030509=IDA, GO:0032924=IDA, GO:0005125=IEA, GO:2000138=ISS, GO:0060038=ISS, GO:0060347=ISS, GO:0010596=IDA, GO:0055117=IMP, GO:0055015=ISS, GO:0060389=IDA, GO:0045893=IDA, GO:0008083=IEA} BMP signaling pathway, activin receptor signaling pathway, adult heart development, atrial cardiac muscle tissue morphogenesis, cardiac muscle cell proliferation, cardiac muscle hypertrophy in response to stress, extracellular matrix organization, heart trabecula formation, negative regulation of cardiac muscle hypertrophy, negative regulation of cell growth, negative regulation of cell migration, negative regulation of endothelial cell migration, pathway-restricted SMAD protein phosphorylation, positive regulation of cardiac muscle cell proliferation, positive regulation of cardiac muscle hypertrophy, positive regulation of cell proliferation involved in heart morphogenesis, positive regulation of pathway-restricted SMAD protein phosphorylation, positive regulation of transcription, DNA-dependent, regulation of cardiac muscle contraction, sarcomere organization, ventricular cardiac muscle cell development, ventricular cardiac muscle tissue morphogenesis Z disc, cell surface, extracellular region, extracellular space cytokine activity, growth factor activity, protein binding, receptor serine/threonine kinase binding Human BMP15 PINC UniProtKB {GO:0060016=GO_REF:0000002, GO:0001541=GO_REF:0000002, GO:0007292=PMID:9849956, GO:0008083=GO_REF:0000037, GO:0005615=GO_REF:0000037, GO:0005125=GO_REF:0000037} O95972 Bone morphogenetic protein 15 protein 20030904 {GO:0060016=IEA, GO:0001541=IEA, GO:0007292=TAS, GO:0008083=IEA, GO:0005615=IEA, GO:0005125=IEA} female gamete generation, granulosa cell development, ovarian follicle development extracellular space cytokine activity, growth factor activity Human BMP2 BHF-UCL UniProtKB {GO:0071773=PMID:20843790, GO:0005515=PMID:18184661, GO:0001658=GO_REF:0000024, GO:0003181=GO_REF:0000024, GO:0046332=PMID:18184661, GO:0009790=GO_REF:0000024, GO:0010894=PMID:19584291, GO:0005615=GO_REF:0000019, GO:0003308=PMID:18545679, GO:0007507=GO_REF:0000024, GO:0072138=GO_REF:0000024, GO:1900745=PMID:22540193, GO:0007219=GO_REF:0000024, GO:0030198=Reactome:REACT_118779, GO:0002062=PMID:16194878, GO:0009887=GO_REF:0000024, GO:0070374=PMID:19664780, GO:0033690=GO_REF:0000024, GO:0004745=GO_REF:0000024, GO:0055007=PMID:21311046, GO:0055008=GO_REF:0000024, GO:0048839=GO_REF:0000024, GO:0030501=PMID:18436533, GO:0030335=GO_REF:0000024, GO:0046982=PMID:7811286, GO:0009986=PMID:22227436, GO:2000726=PMID:18545679, GO:0019211=PMID:9213002, GO:0030509=PMID:20843790, GO:0000122=PMID:19736317, GO:0021978=GO_REF:0000024, GO:0045786=PMID:11502704, GO:0001701=GO_REF:0000024, GO:0005125=GO_REF:0000037, GO:0060039=GO_REF:0000024, GO:0001649=PMID:22705305, GO:0003130=PMID:19736317, GO:0001501=PMID:2315314, GO:0045165=GO_REF:0000024, GO:0070700=PMID:7811286, GO:0045600=GO_REF:0000024, GO:0060485=PMID:20890042, GO:0060389=PMID:16049014, GO:0045893=PMID:16049014, GO:0035630=PMID:16433617, GO:0045892=PMID:15254224, GO:0040007=GO_REF:0000002, GO:0008083=GO_REF:0000037, GO:0051042=PMID:16194878, GO:0008285=PMID:19584291, GO:0042482=GO_REF:0000024, GO:0010718=PMID:20890042, GO:0007267=PMID:2315314, GO:0030177=GO_REF:0000024, GO:0060129=GO_REF:0000024, GO:0001837=PMID:18184661, GO:0030282=GO_REF:0000024, GO:0060395=PMID:17244894, GO:0060128=GO_REF:0000024, GO:0045778=PMID:9213002, GO:0021537=PMID:9187146, GO:0031648=GO_REF:0000019, GO:0060317=PMID:18184661, GO:0000187=PMID:17202865, GO:0006954=GO_REF:0000024, GO:0045944=PMID:16433617, GO:0010922=PMID:9213002, GO:0042475=GO_REF:0000024, GO:1901522=PMID:20843790, GO:0090090=PMID:17202865, GO:0001666=GO_REF:0000024, GO:0006355=PMID:15671031, GO:0043065=PMID:9187146, GO:0048762=PMID:9693150, GO:0010862=PMID:19664780, GO:0035054=GO_REF:0000024, GO:0005102=PMID:2315314, GO:0003203=GO_REF:0000024, GO:0060804=GO_REF:0000024, GO:0005576=Reactome:REACT_150165, GO:0035051=PMID:19736317, GO:0006029=GO_REF:0000019, GO:0045669=PMID:16433617, GO:0010628=PMID:16243309, GO:0071407=GO_REF:0000019, GO:0048711=GO_REF:0000024, GO:0043569=PMID:19584291, GO:0001938=PMID:17992660, GO:0045666=GO_REF:0000024, GO:2000065=PMID:19584291, GO:0061036=PMID:3201241, GO:0001934=PMID:17472960, GO:0042487=GO_REF:0000019, GO:0006468=PMID:22540193, GO:0043410=PMID:22540193, GO:0032348=PMID:19584291} P12643 Bone morphogenetic protein 2 protein 20110120 {GO:0071773=IDA, GO:0005515=IPI, GO:0001658=ISS, GO:0003181=ISS, GO:0046332=IDA, GO:0009790=ISS, GO:0010894=IDA, GO:0005615=IEA, GO:0003308=IDA, GO:0007507=ISS, GO:0072138=ISS, GO:1900745=IDA, GO:0007219=ISS, GO:0030198=TAS, GO:0002062=IDA, GO:0009887=ISS, GO:0070374=IMP, GO:0033690=ISS, GO:0004745=ISS, GO:0055007=IMP, GO:0055008=ISS, GO:0048839=ISS, GO:0030501=IDA, GO:0030335=ISS, GO:0046982=IDA, GO:0009986=IDA, GO:2000726=IDA, GO:0019211=IDA, GO:0030509=IDA, GO:0000122=IDA, GO:0021978=ISS, GO:0045786=IDA, GO:0001701=ISS, GO:0005125=IEA, GO:0060039=ISS, GO:0001649=IDA, GO:0003130=IDA, GO:0001501=TAS, GO:0045165=ISS, GO:0070700=IDA, GO:0045600=ISS, GO:0060485=IMP, GO:0060389=IDA, GO:0045893=IDA, GO:0035630=IDA, GO:0045892=IDA, GO:0040007=IEA, GO:0008083=IEA, GO:0051042=IDA, GO:0008285=IDA, GO:0042482=ISS, GO:0010718=IDA, GO:0007267=TAS, GO:0030177=ISS, GO:0060129=ISS, GO:0001837=IDA, GO:0030282=ISS, GO:0060395=IDA, GO:0060128=ISS, GO:0045778=IDA, GO:0021537=IDA, GO:0031648=IEA, GO:0060317=IDA, GO:0000187=IDA, GO:0006954=ISS, GO:0045944=IDA, GO:0010922=IDA, GO:0042475=ISS, GO:1901522=IDA, GO:0090090=IEP, GO:0001666=ISS, GO:0006355=IDA, GO:0043065=IDA, GO:0048762=IDA, GO:0010862=IMP, GO:0035054=ISS, GO:0005102=TAS, GO:0003203=ISS, GO:0060804=ISS, GO:0005576=TAS, GO:0035051=IMP, GO:0006029=IEA, GO:0045669=IDA, GO:0010628=IDA, GO:0071407=IEA, GO:0048711=ISS, GO:0043569=IDA, GO:0001938=IDA, GO:0045666=ISS, GO:2000065=IDA, GO:0061036=IDA, GO:0001934=IDA, GO:0042487=IEA, GO:0006468=IDA, GO:0043410=IDA, GO:0032348=IDA} BMP signaling pathway, BMP signaling pathway involved in heart induction, Notch signaling pathway, SMAD protein signal transduction, activation of MAPK activity, atrioventricular valve morphogenesis, bone mineralization, bone mineralization involved in bone maturation, branching involved in ureteric bud morphogenesis, cardiac epithelial to mesenchymal transition, cardiac muscle cell differentiation, cardiac muscle tissue morphogenesis, cardiocyte differentiation, cell fate commitment, cell-cell signaling, cellular response to BMP stimulus, cellular response to organic cyclic compound, chondrocyte differentiation, corticotropin hormone secreting cell differentiation, embryo development, embryonic heart tube anterior/posterior pattern specification, endocardial cushion morphogenesis, epithelial to mesenchymal transition, extracellular matrix organization, growth, heart development, in utero embryonic development, inflammatory response, inner ear development, mesenchymal cell differentiation, mesenchymal cell proliferation involved in ureteric bud development, mesenchyme development, negative regulation of Wnt receptor signaling pathway involved in heart development, negative regulation of aldosterone biosynthetic process, negative regulation of calcium-independent cell-cell adhesion, negative regulation of canonical Wnt receptor signaling pathway, negative regulation of cardiac muscle cell differentiation, negative regulation of cell cycle, negative regulation of cell proliferation, negative regulation of cortisol biosynthetic process, negative regulation of insulin-like growth factor receptor signaling pathway, negative regulation of steroid biosynthetic process, negative regulation of transcription from RNA polymerase II promoter, negative regulation of transcription, DNA-dependent, odontogenesis of dentin-containing tooth, organ morphogenesis, osteoblast differentiation, pathway-restricted SMAD protein phosphorylation, pericardium development, positive regulation of ERK1 and ERK2 cascade, positive regulation of MAPK cascade, positive regulation of Wnt receptor signaling pathway, positive regulation of Wnt receptor signaling pathway by BMP signaling pathway, positive regulation of apoptotic process, positive regulation of astrocyte differentiation, positive regulation of bone mineralization, positive regulation of cartilage development, positive regulation of cell migration, positive regulation of endothelial cell proliferation, positive regulation of epithelial to mesenchymal transition, positive regulation of fat cell differentiation, positive regulation of gene expression, positive regulation of neuron differentiation, positive regulation of odontogenesis, positive regulation of ossification, positive regulation of osteoblast differentiation, positive regulation of osteoblast proliferation, positive regulation of p38MAPK cascade, positive regulation of pathway-restricted SMAD protein phosphorylation, positive regulation of phosphatase activity, positive regulation of protein phosphorylation, positive regulation of transcription from RNA polymerase II promoter, positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus, positive regulation of transcription, DNA-dependent, protein destabilization, protein phosphorylation, proteoglycan metabolic process, regulation of odontogenesis of dentin-containing tooth, regulation of transcription, DNA-dependent, response to hypoxia, skeletal system development, telencephalon development, telencephalon regionalization, thyroid-stimulating hormone-secreting cell differentiation cell surface, extracellular region, extracellular space BMP receptor binding, SMAD binding, cytokine activity, growth factor activity, phosphatase activator activity, protein binding, protein heterodimerization activity, receptor binding, retinol dehydrogenase activity Human BMP2K HPA UniProtKB {GO:0030500=GO_REF:0000019, GO:0019208=GO_REF:0000019, GO:0004674=GO_REF:0000037, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0005524=GO_REF:0000037} Q9NSY1 BMP-2-inducible protein kinase protein 20120912 {GO:0030500=IEA, GO:0019208=IEA, GO:0004674=IEA, GO:0005730=IDA, GO:0005634=IDA, GO:0005524=IEA} regulation of bone mineralization nucleolus, nucleus ATP binding, phosphatase regulator activity, protein serine/threonine kinase activity NOT Human BMP3 MGI UniProtKB {GO:0001501=PMID:3201241, GO:0001503=GO_REF:0000037, GO:0070700=PMID:7811286, GO:0051216=GO_REF:0000037, GO:0045944=GO_REF:0000019, GO:0007267=PMID:3201241, GO:0005102=PMID:3201241, GO:0008083=GO_REF:0000037, GO:0005615=GO_REF:0000037, GO:0005125=GO_REF:0000037, GO:0040007=GO_REF:0000002, GO:0030154=GO_REF:0000037} P12645 Bone morphogenetic protein 3 protein 20100311 {GO:0001501=TAS, GO:0001503=IEA, GO:0070700=IPI, GO:0051216=IEA, GO:0045944=IEA, GO:0007267=TAS, GO:0005102=TAS, GO:0008083=IEA, GO:0005615=IEA, GO:0005125=IEA, GO:0040007=IEA, GO:0030154=IEA} cartilage development, cell differentiation, cell-cell signaling, growth, ossification, positive regulation of transcription from RNA polymerase II promoter, skeletal system development extracellular space BMP receptor binding, cytokine activity, growth factor activity, receptor binding Human BMP4 GOC UniProtKB {GO:0005515=PMID:8752214, GO:2000007=PMID:12141440, GO:0034504=PMID:17244894, GO:2000005=PMID:12141440, GO:0003139=PMID:20702560, GO:0009791=PMID:8674409, GO:0048701=GO_REF:0000019, GO:0007281=GO_REF:0000019, GO:0005615=GO_REF:0000024, GO:0045662=PMID:14749725, GO:0002062=GO_REF:0000024, GO:0035990=GO_REF:0000024, GO:0035993=GO_REF:0000024, GO:0060548=PMID:12631064, GO:0060438=PMID:8674409, GO:0090191=PMID:17118062, GO:0090194=PMID:12141440, GO:0060433=PMID:8674409, GO:0010942=PMID:8674409, GO:0061149=GO_REF:0000024, GO:0048392=PMID:10021330, GO:0002320=PMID:12421925, GO:0030501=PMID:18436533, GO:0060235=GO_REF:0000019, GO:0051150=GO_REF:0000019, GO:0070244=PMID:12421925, GO:0072101=PMID:17118062, GO:0003323=PMID:11865031, GO:0072104=GO_REF:0000024, GO:0030509=PMID:18436533, GO:0021978=GO_REF:0000019, GO:0072192=GO_REF:0000024, GO:2000137=PMID:20702560, GO:0005125=PMID:14749725, GO:0042056=PMID:12631064, GO:0045843=PMID:14749725, GO:0072193=GO_REF:0000024, GO:0003130=PMID:20702560, GO:0010595=PMID:17992660, GO:0060442=GO_REF:0000019, GO:0061155=PMID:17992660, GO:0060440=GO_REF:0000019, GO:0060441=PMID:8674409, GO:0032967=PMID:17720811, GO:0061151=GO_REF:0000024, GO:0060449=GO_REF:0000019, GO:0040007=GO_REF:0000002, GO:0072015=GO_REF:0000019, GO:0060592=GO_REF:0000019, GO:0021983=GO_REF:0000019, GO:0021537=PMID:9187146, GO:0060395=PMID:17244894, GO:0060393=PMID:18787191, GO:0000186=PMID:17600318, GO:0072198=GO_REF:0000019, GO:0042476=PMID:11023873, GO:0042475=GO_REF:0000019, GO:0030225=PMID:21149635, GO:0021904=GO_REF:0000019, GO:0030224=PMID:21149635, GO:0072125=PMID:17244894, GO:0060113=GO_REF:0000019, GO:0003197=PMID:18076106, GO:0001822=PMID:18305125, GO:0001823=PMID:18437684, GO:0005578=GO_REF:0000039, GO:0010862=PMID:9389648, GO:0005576=Reactome:REACT_150165, GO:0048663=GO_REF:0000019, GO:0048660=GO_REF:0000019, GO:0048661=PMID:10706139, GO:0050918=PMID:12631064, GO:0045669=PMID:18436533, GO:0042326=PMID:17244894, GO:0003337=PMID:10706139, GO:0071363=GO_REF:0000019, GO:0060197=GO_REF:0000019, GO:0045666=GO_REF:0000019, GO:0030218=GO_REF:0000019, GO:0061036=PMID:3201241, GO:0035116=GO_REF:0000019, GO:0042487=GO_REF:0000019, GO:0048754=PMID:10706139, GO:0033088=PMID:12421925, GO:0001657=PMID:12141440, GO:0001658=PMID:12631064, GO:0033085=PMID:12421925, GO:0050680=GO_REF:0000019, GO:0001759=GO_REF:0000019, GO:0007224=PMID:17850284, GO:0060503=PMID:8674409, GO:0072138=GO_REF:0000019, GO:0030198=Reactome:REACT_118779, GO:0048745=GO_REF:0000024, GO:0060502=PMID:8674409, GO:0061047=GO_REF:0000024, GO:0070374=GO_REF:0000019, GO:0055007=GO_REF:0000019, GO:0060684=GO_REF:0000019, GO:0003279=PMID:18076106, GO:0072200=PMID:12399320, GO:0048286=PMID:8674409, GO:0055020=PMID:20702560, GO:0001843=GO_REF:0000019, GO:0000122=PMID:9187146, GO:0045786=PMID:11502704, GO:0072097=PMID:10706139, GO:0060391=PMID:9389648, GO:0072205=GO_REF:0000024, GO:0001649=PMID:17720811, GO:0060686=GO_REF:0000019, GO:0060687=GO_REF:0000019, GO:0045839=PMID:17244894, GO:0001958=GO_REF:0000024, GO:0070700=PMID:7811286, GO:0060272=GO_REF:0000019, GO:0072001=PMID:17850284, GO:0045893=PMID:17992660, GO:0008083=GO_REF:0000037, GO:0045892=PMID:17244894, GO:0045603=GO_REF:0000019, GO:0042733=GO_REF:0000019, GO:0072161=GO_REF:0000019, GO:0008284=GO_REF:0000019, GO:0008285=PMID:9187146, GO:0090184=PMID:10021330, GO:0060425=PMID:8674409, GO:0002043=PMID:18787191, GO:0045778=PMID:14749725, GO:0030513=GO_REF:0000024, GO:0009948=GO_REF:0000019, GO:0002244=PMID:15451575, GO:0043407=PMID:17244894, GO:0045944=PMID:9187146, GO:0043401=PMID:17244894, GO:0032331=GO_REF:0000019, GO:0008201=GO_REF:0000019, GO:0010159=GO_REF:0000019, GO:0043066=PMID:17992660, GO:0043065=PMID:9187146, GO:0001525=GO_REF:0000019, GO:0003014=GO_REF:0000019, GO:0060363=GO_REF:0000019, GO:0007500=GO_REF:0000019, GO:0001938=PMID:17992660, GO:0010629=GO_REF:0000019, GO:0001934=PMID:14749725, GO:0071893=PMID:10021330, GO:2000105=PMID:15516325} P12644 Bone morphogenetic protein 4 protein 20130413 {GO:0005515=IPI, GO:2000007=IDA, GO:0034504=IDA, GO:2000005=IDA, GO:0003139=IMP, GO:0009791=IDA, GO:0048701=IEA, GO:0007281=IEA, GO:0005615=ISS, GO:0045662=IDA, GO:0002062=ISS, GO:0035990=ISS, GO:0035993=ISS, GO:0060548=IDA, GO:0060438=IDA, GO:0090191=IDA, GO:0090194=IDA, GO:0060433=IDA, GO:0010942=IDA, GO:0061149=ISS, GO:0048392=IDA, GO:0002320=IMP, GO:0030501=IDA, GO:0060235=IEA, GO:0051150=IEA, GO:0070244=IMP, GO:0072101=IDA, GO:0003323=IDA, GO:0072104=ISS, GO:0030509=IDA, GO:0021978=IEA, GO:0072192=ISS, GO:2000137=IMP, GO:0005125=IDA, GO:0042056=IDA, GO:0045843=IDA, GO:0072193=ISS, GO:0003130=IMP, GO:0010595=IDA, GO:0060442=IEA, GO:0061155=IDA, GO:0060440=IEA, GO:0060441=IDA, GO:0032967=IDA, GO:0061151=ISS, GO:0060449=IEA, GO:0040007=IEA, GO:0072015=IEA, GO:0060592=IEA, GO:0021983=IEA, GO:0021537=IDA, GO:0060395=IDA, GO:0060393=IDA, GO:0000186=IDA, GO:0072198=IEA, GO:0042476=IGI, GO:0042475=IEA, GO:0030225=IDA, GO:0021904=IEA, GO:0030224=IDA, GO:0072125=IDA, GO:0060113=IEA, GO:0003197=TAS, GO:0001822=IMP, GO:0001823=IEP, GO:0005578=IEA, GO:0010862=IDA, GO:0005576=TAS, GO:0048663=IEA, GO:0048660=IEA, GO:0048661=IDA, GO:0050918=IDA, GO:0045669=IDA, GO:0042326=IDA, GO:0003337=IDA, GO:0071363=IEA, GO:0060197=IEA, GO:0045666=IEA, GO:0030218=IEA, GO:0061036=IDA, GO:0035116=IEA, GO:0042487=IEA, GO:0048754=IDA, GO:0033088=IMP, GO:0001657=IDA, GO:0001658=IDA, GO:0033085=IMP, GO:0050680=IEA, GO:0001759=IEA, GO:0007224=IEP, GO:0060503=IDA, GO:0072138=IEA, GO:0030198=TAS, GO:0048745=ISS, GO:0060502=IDA, GO:0061047=ISS, GO:0070374=IEA, GO:0055007=IEA, GO:0060684=IEA, GO:0003279=TAS, GO:0072200=IDA, GO:0048286=IDA, GO:0055020=IMP, GO:0001843=IEA, GO:0000122=IDA, GO:0045786=IDA, GO:0072097=IDA, GO:0060391=IDA, GO:0072205=ISS, GO:0001649=IDA, GO:0060686=IEA, GO:0060687=IEA, GO:0045839=IDA, GO:0001958=ISS, GO:0070700=IDA, GO:0060272=IEA, GO:0072001=IEP, GO:0045893=IDA, GO:0008083=IEA, GO:0045892=IDA, GO:0045603=IEA, GO:0042733=IEA, GO:0072161=IEA, GO:0008284=IEA, GO:0008285=IDA, GO:0090184=IDA, GO:0060425=IDA, GO:0002043=IDA, GO:0045778=IDA, GO:0030513=ISS, GO:0009948=IEA, GO:0002244=IDA, GO:0043407=IDA, GO:0045944=IDA, GO:0043401=IMP, GO:0032331=IEA, GO:0008201=IEA, GO:0010159=IEA, GO:0043066=IDA, GO:0043065=IDA, GO:0001525=IEA, GO:0003014=IEA, GO:0060363=IEA, GO:0007500=IEA, GO:0001938=IDA, GO:0010629=IEA, GO:0001934=IDA, GO:0071893=IDA, GO:2000105=IDA} BMP signaling pathway, BMP signaling pathway involved in heart induction, BMP signaling pathway involved in nephric duct formation, BMP signaling pathway involved in renal system segmentation, BMP signaling pathway involved in ureter morphogenesis, SMAD protein signal transduction, activation of MAPKK activity, angiogenesis, anterior/posterior axis specification, blood vessel endothelial cell proliferation involved in sprouting angiogenesis, branching involved in prostate gland morphogenesis, branching involved in ureteric bud morphogenesis, branching morphogenesis of an epithelial tube, bronchus development, bud dilation involved in lung branching, bud elongation involved in lung branching, cardiac muscle cell differentiation, cardiac septum development, cellular response to growth factor stimulus, chondrocyte differentiation, cloacal septation, cranial suture morphogenesis, deltoid tuberosity development, dorsal/ventral neural tube patterning, embryonic cranial skeleton morphogenesis, embryonic digit morphogenesis, embryonic hindlimb morphogenesis, embryonic skeletal joint morphogenesis, endocardial cushion development, endochondral ossification, epithelial cell proliferation involved in lung morphogenesis, epithelial tube branching involved in lung morphogenesis, epithelial-mesenchymal cell signaling, erythrocyte differentiation, extracellular matrix organization, germ cell development, glomerular capillary formation, glomerular visceral epithelial cell development, growth, hematopoietic progenitor cell differentiation, inner ear receptor cell differentiation, intermediate mesodermal cell differentiation, kidney development, lens induction in camera-type eye, lung alveolus development, lung morphogenesis, lymphoid progenitor cell differentiation, macrophage differentiation, mammary gland formation, mesenchymal cell differentiation involved in kidney development, mesenchymal cell proliferation involved in ureter development, mesenchymal cell proliferation involved in ureteric bud development, mesenchymal to epithelial transition involved in metanephros morphogenesis, mesodermal cell fate determination, mesonephros development, metanephric collecting duct development, monocyte differentiation, negative regulation of MAP kinase activity, negative regulation of T cell differentiation in thymus, negative regulation of apoptotic process, negative regulation of branch elongation involved in ureteric bud branching by BMP signaling pathway, negative regulation of branching involved in ureteric bud morphogenesis, negative regulation of cell cycle, negative regulation of cell death, negative regulation of cell proliferation, negative regulation of cell proliferation involved in heart morphogenesis, negative regulation of chondrocyte differentiation, negative regulation of epithelial cell proliferation, negative regulation of gene expression, negative regulation of glomerular mesangial cell proliferation, negative regulation of glomerulus development, negative regulation of immature T cell proliferation in thymus, negative regulation of mesenchymal cell proliferation involved in ureter development, negative regulation of metanephric S-shaped body morphogenesis, negative regulation of metanephric comma-shaped body morphogenesis, negative regulation of mitosis, negative regulation of myoblast differentiation, negative regulation of phosphorylation, negative regulation of prostatic bud formation, negative regulation of striated muscle tissue development, negative regulation of thymocyte apoptotic process, negative regulation of transcription from RNA polymerase II promoter, negative regulation of transcription, DNA-dependent, neural tube closure, neuron fate commitment, odontogenesis, odontogenesis of dentin-containing tooth, organ induction, osteoblast differentiation, pituitary gland development, positive chemotaxis, positive regulation of BMP signaling pathway, positive regulation of DNA-dependent DNA replication, positive regulation of ERK1 and ERK2 cascade, positive regulation of SMAD protein import into nucleus, positive regulation of apoptotic process, positive regulation of bone mineralization, positive regulation of branching involved in lung morphogenesis, positive regulation of cardiac muscle fiber development, positive regulation of cartilage development, positive regulation of cell death, positive regulation of cell proliferation, positive regulation of collagen biosynthetic process, positive regulation of endothelial cell differentiation, positive regulation of endothelial cell migration, positive regulation of endothelial cell proliferation, positive regulation of kidney development, positive regulation of neuron differentiation, positive regulation of ossification, positive regulation of osteoblast differentiation, positive regulation of pathway-restricted SMAD protein phosphorylation, positive regulation of protein phosphorylation, positive regulation of smooth muscle cell proliferation, positive regulation of transcription from RNA polymerase II promoter, positive regulation of transcription, DNA-dependent, post-embryonic development, protein localization to nucleus, pulmonary artery endothelial tube morphogenesis, regulation of branching involved in prostate gland morphogenesis, regulation of odontogenesis of dentin-containing tooth, regulation of pathway-restricted SMAD protein phosphorylation, regulation of smooth muscle cell differentiation, regulation of smooth muscle cell proliferation, renal system development, renal system process, secondary heart field specification, smooth muscle tissue development, smoothened signaling pathway, specification of organ position, specification of ureteric bud anterior/posterior symmetry by BMP signaling pathway, steroid hormone mediated signaling pathway, telencephalon development, telencephalon regionalization, tendon cell differentiation, trachea development, trachea formation, type B pancreatic cell development, ureter epithelial cell differentiation, ureter smooth muscle cell differentiation, ureteric bud development extracellular region, extracellular space, proteinaceous extracellular matrix BMP receptor binding, chemoattractant activity, cytokine activity, growth factor activity, heparin binding, protein binding Human BMP5 BHF-UCL UniProtKB {GO:0008285=PMID:19584291, GO:0051216=GO_REF:0000037, GO:0031988=GO_REF:0000024, GO:0003323=PMID:11865031, GO:0005576=GO_REF:0000038, GO:0010719=PMID:21319131, GO:0005575=GO_REF:0000015, GO:0005615=GO_REF:0000024, GO:0010894=PMID:19584291, GO:0005125=GO_REF:0000029, GO:0001501=PMID:2263636, GO:0001503=GO_REF:0000037, GO:0043569=PMID:19584291, GO:0070700=PMID:7811286, GO:2000065=PMID:19584291, GO:2000105=PMID:15516325, GO:0040007=GO_REF:0000002, GO:0008083=GO_REF:0000037, GO:0032348=PMID:19584291} P22003 Bone morphogenetic protein 5 protein 20120503 {GO:0008285=IDA, GO:0051216=IEA, GO:0031988=ISS, GO:0003323=IDA, GO:0005576=IEA, GO:0010719=NAS, GO:0005575=ND, GO:0005615=ISS, GO:0010894=IDA, GO:0005125=NAS, GO:0001501=NAS, GO:0001503=IEA, GO:0043569=IDA, GO:0070700=IPI, GO:2000065=IDA, GO:2000105=IDA, GO:0040007=IEA, GO:0008083=IEA, GO:0032348=IDA} cartilage development, growth, negative regulation of aldosterone biosynthetic process, negative regulation of cell proliferation, negative regulation of cortisol biosynthetic process, negative regulation of epithelial to mesenchymal transition, negative regulation of insulin-like growth factor receptor signaling pathway, negative regulation of steroid biosynthetic process, ossification, positive regulation of DNA-dependent DNA replication, skeletal system development, type B pancreatic cell development cellular_component, extracellular region, extracellular space, membrane-bounded vesicle BMP receptor binding, cytokine activity, growth factor activity Human UniProtKB:D4A7P9 BMP6 BHF-UCL UniProtKB {GO:0051216=GO_REF:0000037, GO:0001654=GO_REF:0000019, GO:0005615=GO_REF:0000019, GO:0060395=PMID:17244894, GO:0030539=GO_REF:0000019, GO:0006955=PMID:16886151, GO:0005737=GO_REF:0000019, GO:0006954=GO_REF:0000019, GO:0045944=PMID:16527843, GO:0032526=GO_REF:0000019, GO:0030501=PMID:18436533, GO:0046982=PMID:7811286, GO:0001822=GO_REF:0000019, GO:0031988=GO_REF:0000019, GO:0010862=PMID:17244894, GO:0003323=PMID:11865031, GO:0051384=GO_REF:0000019, GO:0030509=PMID:18436533, GO:0005125=GO_REF:0000037, GO:0001649=GO_REF:0000019, GO:0045669=PMID:18436533, GO:0001501=PMID:8089189, GO:0001958=GO_REF:0000019, GO:0001938=GO_REF:0000019, GO:0045666=GO_REF:0000019, GO:0070700=PMID:7811286, GO:2000105=PMID:15516325, GO:0040007=GO_REF:0000002, GO:0045603=GO_REF:0000019, GO:0008083=GO_REF:0000037, GO:0032349=PMID:16527843} P22004 Bone morphogenetic protein 6 protein 20120501 {GO:0051216=IEA, GO:0001654=IEA, GO:0005615=IEA, GO:0060395=IDA, GO:0030539=IEA, GO:0006955=IMP, GO:0005737=IEA, GO:0006954=IEA, GO:0045944=IDA, GO:0032526=IEA, GO:0030501=IDA, GO:0046982=IDA, GO:0001822=IEA, GO:0031988=IEA, GO:0010862=IDA, GO:0003323=IDA, GO:0051384=IEA, GO:0030509=IDA, GO:0005125=IEA, GO:0001649=IEA, GO:0045669=IDA, GO:0001501=TAS, GO:0001958=IEA, GO:0001938=IEA, GO:0045666=IEA, GO:0070700=IPI, GO:2000105=NAS, GO:0040007=IEA, GO:0045603=IEA, GO:0008083=IEA, GO:0032349=IDA} BMP signaling pathway, SMAD protein signal transduction, cartilage development, endochondral ossification, eye development, growth, immune response, inflammatory response, kidney development, male genitalia development, osteoblast differentiation, positive regulation of DNA-dependent DNA replication, positive regulation of aldosterone biosynthetic process, positive regulation of bone mineralization, positive regulation of endothelial cell differentiation, positive regulation of endothelial cell proliferation, positive regulation of neuron differentiation, positive regulation of osteoblast differentiation, positive regulation of pathway-restricted SMAD protein phosphorylation, positive regulation of transcription from RNA polymerase II promoter, response to glucocorticoid stimulus, response to retinoic acid, skeletal system development, type B pancreatic cell development cytoplasm, extracellular space, membrane-bounded vesicle BMP receptor binding, cytokine activity, growth factor activity, protein heterodimerization activity Human BMP7 BHF-UCL UniProtKB {GO:0005515=PMID:18184661, GO:0001656=PMID:18437684, GO:0001657=GO_REF:0000024, GO:0034504=PMID:17244894, GO:0051216=GO_REF:0000037, GO:0005615=PMID:17977014, GO:0048596=GO_REF:0000019, GO:0009880=GO_REF:0000019, GO:0030198=Reactome:REACT_118779, GO:0007411=GO_REF:0000019, GO:0060548=PMID:12631064, GO:0072040=GO_REF:0000019, GO:0034116=PMID:15100360, GO:0072136=GO_REF:0000019, GO:0072134=GO_REF:0000019, GO:0010664=GO_REF:0000024, GO:0072133=GO_REF:0000019, GO:0045746=GO_REF:0000019, GO:0030501=PMID:18436533, GO:0001707=GO_REF:0000019, GO:0030509=PMID:18436533, GO:0045786=PMID:11502704, GO:0005125=GO_REF:0000037, GO:0060686=GO_REF:0000019, GO:0060687=GO_REF:0000019, GO:0045839=PMID:17244894, GO:0001501=PMID:2357959, GO:0001503=GO_REF:0000037, GO:0060272=GO_REF:0000019, GO:0070487=PMID:15100360, GO:0060485=GO_REF:0000024, GO:0045893=PMID:16049014, GO:0040007=GO_REF:0000002, GO:0008083=GO_REF:0000037, GO:0045892=PMID:17244894, GO:0060445=GO_REF:0000019, GO:0042347=GO_REF:0000024, GO:0030326=GO_REF:0000019, GO:0001837=PMID:14679171, GO:0060395=PMID:17244894, GO:2000121=GO_REF:0000024, GO:0060393=PMID:16049014, GO:1900106=PMID:15100360, GO:0050768=GO_REF:0000019, GO:0045944=GO_REF:0000019, GO:0043407=PMID:17244894, GO:0030855=GO_REF:0000019, GO:0043401=PMID:17244894, GO:0042475=GO_REF:0000019, GO:0072125=PMID:17244894, GO:0043065=GO_REF:0000019, GO:0001823=PMID:18437684, GO:0048762=PMID:9693150, GO:0010862=PMID:19736306, GO:0071456=GO_REF:0000024, GO:0032088=GO_REF:0000024, GO:0005576=Reactome:REACT_150165, GO:0045669=PMID:18436533, GO:0042326=PMID:17244894, GO:0045665=PMID:16325379, GO:0045666=GO_REF:0000019, GO:0048812=PMID:16325379, GO:0048754=GO_REF:0000019} P18075 Bone morphogenetic protein 7 protein 20120312 {GO:0005515=IPI, GO:0001656=IEP, GO:0001657=ISS, GO:0034504=IDA, GO:0051216=IEA, GO:0005615=IDA, GO:0048596=IEA, GO:0009880=IEA, GO:0030198=TAS, GO:0007411=IEA, GO:0060548=IDA, GO:0072040=IEA, GO:0034116=IDA, GO:0072136=IEA, GO:0072134=IEA, GO:0010664=ISS, GO:0072133=IEA, GO:0045746=IEA, GO:0030501=IDA, GO:0001707=IEA, GO:0030509=IDA, GO:0045786=IDA, GO:0005125=IEA, GO:0060686=IEA, GO:0060687=IEA, GO:0045839=IDA, GO:0001501=TAS, GO:0001503=IEA, GO:0060272=IEA, GO:0070487=IDA, GO:0060485=ISS, GO:0045893=IDA, GO:0040007=IEA, GO:0008083=IEA, GO:0045892=IDA, GO:0060445=IEA, GO:0042347=ISS, GO:0030326=IEA, GO:0001837=TAS, GO:0060395=IDA, GO:2000121=ISS, GO:0060393=IDA, GO:1900106=IDA, GO:0050768=IEA, GO:0045944=IEA, GO:0043407=IDA, GO:0030855=IEA, GO:0043401=IMP, GO:0042475=IEA, GO:0072125=IDA, GO:0043065=IEA, GO:0001823=IEP, GO:0048762=IDA, GO:0010862=IDA, GO:0071456=ISS, GO:0032088=ISS, GO:0005576=TAS, GO:0045669=IDA, GO:0042326=IDA, GO:0045665=IDA, GO:0045666=IEA, GO:0048812=IDA, GO:0048754=IEA} BMP signaling pathway, SMAD protein signal transduction, axon guidance, branching involved in salivary gland morphogenesis, branching morphogenesis of an epithelial tube, cartilage development, cellular response to hypoxia, embryonic camera-type eye morphogenesis, embryonic limb morphogenesis, embryonic pattern specification, embryonic skeletal joint morphogenesis, epithelial cell differentiation, epithelial to mesenchymal transition, extracellular matrix organization, growth, mesenchymal cell differentiation, mesenchyme development, mesoderm formation, mesonephros development, metanephric mesenchymal cell proliferation involved in metanephros development, metanephric mesenchyme morphogenesis, metanephros development, monocyte aggregation, negative regulation of MAP kinase activity, negative regulation of NF-kappaB import into nucleus, negative regulation of NF-kappaB transcription factor activity, negative regulation of Notch signaling pathway, negative regulation of cell cycle, negative regulation of cell death, negative regulation of glomerular mesangial cell proliferation, negative regulation of mesenchymal cell apoptotic process involved in nephron morphogenesis, negative regulation of mitosis, negative regulation of neurogenesis, negative regulation of neuron differentiation, negative regulation of phosphorylation, negative regulation of prostatic bud formation, negative regulation of striated muscle cell apoptotic process, negative regulation of transcription, DNA-dependent, nephrogenic mesenchyme morphogenesis, neuron projection morphogenesis, odontogenesis of dentin-containing tooth, ossification, positive regulation of apoptotic process, positive regulation of bone mineralization, positive regulation of heterotypic cell-cell adhesion, positive regulation of hyaluranon cable assembly, positive regulation of neuron differentiation, positive regulation of osteoblast differentiation, positive regulation of pathway-restricted SMAD protein phosphorylation, positive regulation of transcription from RNA polymerase II promoter, positive regulation of transcription, DNA-dependent, protein localization to nucleus, regulation of branching involved in prostate gland morphogenesis, regulation of pathway-restricted SMAD protein phosphorylation, regulation of removal of superoxide radicals, skeletal system development, steroid hormone mediated signaling pathway, ureteric bud development extracellular region, extracellular space cytokine activity, growth factor activity, protein binding Human BMP8A UniProtKB UniProtKB {GO:0001503=GO_REF:0000037, GO:0051216=GO_REF:0000037, GO:0008083=GO_REF:0000037, GO:0005615=GO_REF:0000037, GO:0005125=GO_REF:0000037, GO:0040007=GO_REF:0000002, GO:0030154=GO_REF:0000037} Q7Z5Y6 Bone morphogenetic protein 8A protein 20130413 {GO:0001503=IEA, GO:0051216=IEA, GO:0008083=IEA, GO:0005615=IEA, GO:0005125=IEA, GO:0040007=IEA, GO:0030154=IEA} cartilage development, cell differentiation, growth, ossification extracellular space cytokine activity, growth factor activity Human UniProtKB-KW:KW-0891 BMP8B PINC UniProtKB {GO:0001501=PMID:1460021, GO:0001503=GO_REF:0000037, GO:0051216=GO_REF:0000037, GO:0005576=GO_REF:0000038, GO:0005615=GO_REF:0000037, GO:0005125=GO_REF:0000037, GO:0008083=GO_REF:0000037, GO:0040007=GO_REF:0000002, GO:0030154=GO_REF:0000037} P34820 Bone morphogenetic protein 8B protein 20030904 {GO:0001501=TAS, GO:0001503=IEA, GO:0051216=IEA, GO:0005576=IEA, GO:0005615=IEA, GO:0005125=IEA, GO:0008083=IEA, GO:0040007=IEA, GO:0030154=IEA} cartilage development, cell differentiation, growth, ossification, skeletal system development extracellular region, extracellular space cytokine activity, growth factor activity Human BMPER BHF-UCL UniProtKB {GO:0030514=PMID:18787191, GO:0001657=GO_REF:0000019, GO:0048839=GO_REF:0000019, GO:0010594=PMID:18787191, GO:0002043=PMID:18787191, GO:0042118=PMID:18787191, GO:0070374=PMID:18787191, GO:0005615=PMID:18787191, GO:0060393=PMID:18787191} Q8N8U9 BMP-binding endothelial regulator protein protein 20100520 {GO:0030514=TAS, GO:0001657=IEA, GO:0048839=IEA, GO:0010594=IDA, GO:0002043=IDA, GO:0042118=IDA, GO:0070374=IDA, GO:0005615=IDA, GO:0060393=IDA} blood vessel endothelial cell proliferation involved in sprouting angiogenesis, endothelial cell activation, inner ear development, negative regulation of BMP signaling pathway, positive regulation of ERK1 and ERK2 cascade, regulation of endothelial cell migration, regulation of pathway-restricted SMAD protein phosphorylation, ureteric bud development extracellular space Human BMPR1A BHF-UCL UniProtKB {GO:0035137=GO_REF:0000019, GO:0005515=PMID:18184661, GO:0051216=GO_REF:0000019, GO:0000981=GO_REF:0000019, GO:0001756=GO_REF:0000019, GO:0046332=PMID:12065756, GO:0042803=PMID:18436533, GO:0048589=GO_REF:0000019, GO:0060914=GO_REF:0000019, GO:0014032=GO_REF:0000019, GO:0048352=GO_REF:0000019, GO:0043025=GO_REF:0000019, GO:0007179=PMID:8397373, GO:0050679=GO_REF:0000019, GO:0001707=GO_REF:0000019, GO:0030501=PMID:18436533, GO:0003272=GO_REF:0000024, GO:0030509=PMID:18436533, GO:0001701=GO_REF:0000019, GO:0060391=PMID:9389648, GO:0045893=GO_REF:0000019, GO:0042733=GO_REF:0000019, GO:0048382=GO_REF:0000019, GO:0005886=PMID:15657086, GO:0030324=GO_REF:0000019, GO:0021983=GO_REF:0000019, GO:0030425=GO_REF:0000019, GO:0046872=GO_REF:0000037, GO:0009950=GO_REF:0000019, GO:0048378=GO_REF:0000019, GO:0006955=PMID:16886151, GO:0050768=GO_REF:0000019, GO:0048568=GO_REF:0000019, GO:0001880=GO_REF:0000019, GO:0060021=GO_REF:0000019, GO:0042475=GO_REF:0000019, GO:0005024=GO_REF:0000002, GO:0021998=GO_REF:0000019, GO:0010862=PMID:9389648, GO:0002053=GO_REF:0000019, GO:0007398=GO_REF:0000019, GO:0005524=PMID:12065756, GO:0045669=PMID:18436533, GO:0048368=GO_REF:0000019, GO:0004674=PMID:12065756, GO:0019827=GO_REF:0000019, GO:0004675=Reactome:REACT_12052, GO:0005901=PMID:15657086, GO:0006468=PMID:12065756, GO:0016021=GO_REF:0000037} P36894 Bone morphogenetic protein receptor type-1A protein 20120925 {GO:0035137=IEA, GO:0005515=IPI, GO:0051216=IEA, GO:0000981=IEA, GO:0001756=IEA, GO:0046332=IDA, GO:0042803=IDA, GO:0048589=IEA, GO:0060914=IEA, GO:0014032=IEA, GO:0048352=IEA, GO:0043025=IEA, GO:0007179=TAS, GO:0050679=IEA, GO:0001707=IEA, GO:0030501=IMP, GO:0003272=ISS, GO:0030509=IDA, GO:0001701=IEA, GO:0060391=IDA, GO:0045893=IEA, GO:0042733=IEA, GO:0048382=IEA, GO:0005886=IDA, GO:0030324=IEA, GO:0021983=IEA, GO:0030425=IEA, GO:0046872=IEA, GO:0009950=IEA, GO:0048378=IEA, GO:0006955=IMP, GO:0050768=IEA, GO:0048568=IEA, GO:0001880=IEA, GO:0060021=IEA, GO:0042475=IEA, GO:0005024=IEA, GO:0021998=IEA, GO:0010862=IDA, GO:0002053=IEA, GO:0007398=IEA, GO:0005524=IDA, GO:0045669=IMP, GO:0048368=IEA, GO:0004674=IDA, GO:0019827=IEA, GO:0004675=TAS, GO:0005901=IMP, GO:0006468=IDA, GO:0016021=IEA} BMP signaling pathway, Mullerian duct regression, cartilage development, developmental growth, dorsal/ventral axis specification, ectoderm development, embryonic digit morphogenesis, embryonic organ development, endocardial cushion formation, heart formation, hindlimb morphogenesis, immune response, in utero embryonic development, lateral mesoderm development, lung development, mesendoderm development, mesoderm formation, negative regulation of neurogenesis, neural crest cell development, neural plate mediolateral regionalization, odontogenesis of dentin-containing tooth, palate development, paraxial mesoderm structural organization, pituitary gland development, positive regulation of SMAD protein import into nucleus, positive regulation of bone mineralization, positive regulation of epithelial cell proliferation, positive regulation of mesenchymal cell proliferation, positive regulation of osteoblast differentiation, positive regulation of pathway-restricted SMAD protein phosphorylation, positive regulation of transcription, DNA-dependent, protein phosphorylation, regulation of lateral mesodermal cell fate specification, somitogenesis, stem cell maintenance, transforming growth factor beta receptor signaling pathway caveola, dendrite, integral to membrane, neuronal cell body, plasma membrane ATP binding, SMAD binding, metal ion binding, protein binding, protein homodimerization activity, protein serine/threonine kinase activity, sequence-specific DNA binding RNA polymerase II transcription factor activity, transforming growth factor beta-activated receptor activity, transmembrane receptor protein serine/threonine kinase activity Human UniProtKB:P36895 BMPR1B BHF-UCL UniProtKB {GO:0031290=GO_REF:0000019, GO:0005515=PMID:18184661, GO:0060041=GO_REF:0000019, GO:0005886=Reactome:REACT_115888, GO:0001654=GO_REF:0000024, GO:0045597=PMID:14523231, GO:0042698=GO_REF:0000024, GO:0046332=PMID:12065756, GO:0009953=GO_REF:0000019, GO:0046872=GO_REF:0000037, GO:0006954=GO_REF:0000019, GO:0004702=GO_REF:0000002, GO:0005024=GO_REF:0000002, GO:0035108=PMID:14523231, GO:0005025=GO_REF:0000019, GO:0030501=PMID:18436533, GO:0030509=PMID:18436533, GO:0005524=PMID:12065756, GO:0045669=PMID:18436533, GO:0043235=PMID:14523231, GO:0001501=PMID:14523231, GO:0016020=GO_REF:0000002, GO:0001502=PMID:14523231, GO:0005887=PMID:14523231, GO:0004674=PMID:12065756, GO:0004675=PMID:14523231, GO:0001550=GO_REF:0000024, GO:0006468=PMID:12065756} O00238 Bone morphogenetic protein receptor type-1B protein 20080822 {GO:0031290=IEA, GO:0005515=IPI, GO:0060041=IEA, GO:0005886=TAS, GO:0001654=ISS, GO:0045597=IMP, GO:0042698=ISS, GO:0046332=IDA, GO:0009953=IEA, GO:0046872=IEA, GO:0006954=IEA, GO:0004702=IEA, GO:0005024=IEA, GO:0035108=IMP, GO:0005025=IEA, GO:0030501=IMP, GO:0030509=IDA, GO:0005524=IDA, GO:0045669=IMP, GO:0043235=TAS, GO:0001501=IMP, GO:0016020=IEA, GO:0001502=NAS, GO:0005887=IC, GO:0004674=IDA, GO:0004675=IMP, GO:0001550=ISS, GO:0006468=IDA} BMP signaling pathway, cartilage condensation, dorsal/ventral pattern formation, eye development, inflammatory response, limb morphogenesis, ovarian cumulus expansion, ovulation cycle, positive regulation of bone mineralization, positive regulation of cell differentiation, positive regulation of osteoblast differentiation, protein phosphorylation, retina development in camera-type eye, retinal ganglion cell axon guidance, skeletal system development integral to plasma membrane, membrane, plasma membrane, receptor complex ATP binding, SMAD binding, metal ion binding, protein binding, protein serine/threonine kinase activity, receptor signaling protein serine/threonine kinase activity, transforming growth factor beta receptor activity, type I, transforming growth factor beta-activated receptor activity, transmembrane receptor protein serine/threonine kinase activity Human UniProtKB:P12643 BMPR2 BHF-UCL UniProtKB {GO:0005515=PMID:12045205, GO:0030308=PMID:12819188, GO:0014916=PMID:18364108, GO:0005886=PMID:15657086, GO:0006366=PMID:12045205, GO:0061298=GO_REF:0000024, GO:0009952=GO_REF:0000024, GO:0060836=GO_REF:0000024, GO:0046872=GO_REF:0000037, GO:0016362=Reactome:REACT_12070, GO:0001946=GO_REF:0000024, GO:0030513=PMID:17992660, GO:0045906=GO_REF:0000024, GO:0042127=PMID:11502704, GO:0007178=PMID:12045205, GO:0005024=GO_REF:0000002, GO:0003085=PMID:18364108, GO:0009267=PMID:15657086, GO:0048010=GO_REF:0000024, GO:0030501=PMID:18436533, GO:0001707=GO_REF:0000024, GO:0048286=GO_REF:0000024, GO:0009986=GO_REF:0000019, GO:0010862=PMID:17992660, GO:0030509=PMID:19366699, GO:0005524=GO_REF:0000037, GO:0045669=PMID:18436533, GO:0010595=PMID:17992660, GO:0001938=PMID:17992660, GO:0016020=GO_REF:0000002, GO:0005887=PMID:12045205, GO:0005901=PMID:15657086, GO:0001934=PMID:17472960, GO:0010634=PMID:12819188} Q13873 Bone morphogenetic protein receptor type-2 protein 20120319 {GO:0005515=IPI, GO:0030308=IDA, GO:0014916=IMP, GO:0005886=IDA, GO:0006366=IMP, GO:0061298=ISS, GO:0009952=ISS, GO:0060836=ISS, GO:0046872=IEA, GO:0016362=TAS, GO:0001946=ISS, GO:0030513=IMP, GO:0045906=ISS, GO:0042127=IMP, GO:0007178=IDA, GO:0005024=IEA, GO:0003085=IMP, GO:0009267=IEP, GO:0048010=ISS, GO:0030501=IMP, GO:0001707=ISS, GO:0048286=ISS, GO:0009986=IEA, GO:0010862=IMP, GO:0030509=IMP, GO:0005524=IEA, GO:0045669=IMP, GO:0010595=IMP, GO:0001938=IMP, GO:0016020=IEA, GO:0005887=IDA, GO:0005901=IMP, GO:0001934=IMP, GO:0010634=IDA} BMP signaling pathway, anterior/posterior pattern specification, cellular response to starvation, lung alveolus development, lymphangiogenesis, lymphatic endothelial cell differentiation, mesoderm formation, negative regulation of cell growth, negative regulation of systemic arterial blood pressure, negative regulation of vasoconstriction, positive regulation of BMP signaling pathway, positive regulation of bone mineralization, positive regulation of endothelial cell migration, positive regulation of endothelial cell proliferation, positive regulation of epithelial cell migration, positive regulation of osteoblast differentiation, positive regulation of pathway-restricted SMAD protein phosphorylation, positive regulation of protein phosphorylation, regulation of cell proliferation, regulation of lung blood pressure, retina vasculature development in camera-type eye, transcription from RNA polymerase II promoter, transmembrane receptor protein serine/threonine kinase signaling pathway, vascular endothelial growth factor receptor signaling pathway caveola, cell surface, integral to plasma membrane, membrane, plasma membrane ATP binding, activin receptor activity, type II, metal ion binding, protein binding, transforming growth factor beta-activated receptor activity Human UniProtKB:O35607 BMS1 HPA UniProtKB {GO:0042255=GO_REF:0000024, GO:0005730=GO_REF:0000052, GO:0003924=GO_REF:0000002, GO:0005634=GO_REF:0000052, GO:0005525=GO_REF:0000002, GO:0005524=GO_REF:0000037} Q14692 Ribosome biogenesis protein BMS1 homolog protein 20110516 {GO:0042255=ISS, GO:0005730=IDA, GO:0003924=IEA, GO:0005634=IDA, GO:0005525=IEA, GO:0005524=IEA} ribosome assembly nucleolus, nucleus ATP binding, GTP binding, GTPase activity Human BMX IntAct UniProtKB {GO:0005515=PMID:16186805, GO:0006950=GO_REF:0000037, GO:0006915=Reactome:REACT_578, GO:0032587=PMID:11331870, GO:0005524=GO_REF:0000037, GO:0006921=Reactome:REACT_995, GO:0046872=GO_REF:0000037, GO:0005829=Reactome:REACT_13417, GO:0035556=GO_REF:0000002, GO:0007165=PMID:11331870, GO:0005543=GO_REF:0000002, GO:0046777=PMID:11331870, GO:0006468=PMID:7970727, GO:0007498=PMID:9520419, GO:0004871=PMID:9520419, GO:0004713=PMID:7970727, GO:0007155=GO_REF:0000037, GO:0004715=PMID:11331870} P51813 Cytoplasmic tyrosine-protein kinase BMX protein 20130415 {GO:0005515=IPI, GO:0006950=IEA, GO:0006915=TAS, GO:0032587=IDA, GO:0005524=IEA, GO:0006921=TAS, GO:0046872=IEA, GO:0005829=TAS, GO:0035556=IEA, GO:0007165=IDA, GO:0005543=IEA, GO:0046777=IDA, GO:0006468=TAS, GO:0007498=TAS, GO:0004871=TAS, GO:0004713=TAS, GO:0007155=IEA, GO:0004715=IDA} apoptotic process, cell adhesion, cellular component disassembly involved in execution phase of apoptosis, intracellular signal transduction, mesoderm development, protein autophosphorylation, protein phosphorylation, response to stress, signal transduction cytosol, ruffle membrane ATP binding, metal ion binding, non-membrane spanning protein tyrosine kinase activity, phospholipid binding, protein binding, protein tyrosine kinase activity, signal transducer activity Human UniProtKB:P11309 BNC1 PINC UniProtKB {GO:0050679=GO_REF:0000019, GO:0051276=GO_REF:0000019, GO:0008284=PMID:8034748, GO:0003700=PMID:9099851, GO:0006357=GO_REF:0000019, GO:0006356=GO_REF:0000019, GO:0005634=GO_REF:0000039, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037, GO:0005737=GO_REF:0000039, GO:0008544=PMID:1332044, GO:0042060=GO_REF:0000019, GO:0008270=GO_REF:0000002} Q01954 Zinc finger protein basonuclin-1 protein 20030904 {GO:0050679=IEA, GO:0051276=IEA, GO:0008284=TAS, GO:0003700=TAS, GO:0006357=IEA, GO:0006356=IEA, GO:0005634=IEA, GO:0003677=IEA, GO:0006351=IEA, GO:0005737=IEA, GO:0008544=TAS, GO:0042060=IEA, GO:0008270=IEA} chromosome organization, epidermis development, positive regulation of cell proliferation, positive regulation of epithelial cell proliferation, regulation of transcription from RNA polymerase I promoter, regulation of transcription from RNA polymerase II promoter, transcription, DNA-dependent, wound healing cytoplasm, nucleus DNA binding, sequence-specific DNA binding transcription factor activity, zinc ion binding Human BNC2 HPA UniProtKB {GO:0006355=GO_REF:0000037, GO:0005737=GO_REF:0000052, GO:0005886=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0008270=GO_REF:0000002, GO:0003677=GO_REF:0000019, GO:0006351=GO_REF:0000037} Q6ZN30 Zinc finger protein basonuclin-2 protein 20090616 {GO:0006355=IEA, GO:0005737=IDA, GO:0005886=IDA, GO:0005634=IDA, GO:0008270=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent cytoplasm, nucleus, plasma membrane DNA binding, zinc ion binding Human BNIP1 HGNC UniProtKB {GO:0005515=PMID:15272311, GO:0043066=PMID:7954800, GO:0005783=PMID:15272311, GO:0006914=GO_REF:0000037, GO:0031201=PMID:15272311, GO:0006915=PMID:7954800, GO:0030176=PMID:15272311, GO:0005635=PMID:7954800, GO:0006917=PMID:15272311, GO:0043231=PMID:7954800, GO:0005739=GO_REF:0000039, GO:0005737=PMID:7954800, GO:0016320=PMID:15272311, GO:0016192=GO_REF:0000037, GO:0007029=PMID:15272311} Q12981 Vesicle transport protein SEC20 protein 20060522 {GO:0005515=IPI, GO:0043066=TAS, GO:0005783=IDA, GO:0006914=IEA, GO:0031201=IDA, GO:0006915=IPI, GO:0030176=TAS, GO:0005635=IDA, GO:0006917=IMP, GO:0043231=IDA, GO:0005739=IEA, GO:0005737=IDA, GO:0016320=IMP, GO:0016192=IEA, GO:0007029=IMP} apoptotic process, autophagy, endoplasmic reticulum membrane fusion, endoplasmic reticulum organization, induction of apoptosis, negative regulation of apoptotic process, vesicle-mediated transport SNARE complex, cytoplasm, endoplasmic reticulum, integral to endoplasmic reticulum membrane, intracellular membrane-bounded organelle, mitochondrion, nuclear envelope protein binding Human UniProtKB:Q9P2W9 BNIP2 GOC UniProtKB {GO:0005515=PMID:10381623, GO:0043066=PMID:7954800, GO:0048471=GO_REF:0000039, GO:0005814=GO_REF:0000019, GO:0051057=GO_REF:0000019, GO:0001824=GO_REF:0000019, GO:0005509=PMID:7954800, GO:0006915=PMID:7954800, GO:0005635=PMID:7954800, GO:0005829=Reactome:REACT_21288, GO:0043231=PMID:7954800, GO:0043547=PMID:10799524, GO:0042692=Reactome:REACT_21303, GO:0005737=PMID:7954800, GO:0051149=Reactome:REACT_21402, GO:0045666=GO_REF:0000019, GO:0031616=GO_REF:0000019, GO:0043410=GO_REF:0000019, GO:0051300=GO_REF:0000019, GO:0051146=GO_REF:0000019, GO:0005096=PMID:10799524} Q12982 BCL2/adenovirus E1B 19 kDa protein-interacting protein 2 protein 20130413 {GO:0005515=IPI, GO:0043066=TAS, GO:0048471=IEA, GO:0005814=IEA, GO:0051057=IEA, GO:0001824=IEA, GO:0005509=TAS, GO:0006915=IPI, GO:0005635=IDA, GO:0005829=TAS, GO:0043231=IDA, GO:0043547=TAS, GO:0042692=TAS, GO:0005737=IDA, GO:0051149=TAS, GO:0045666=IEA, GO:0031616=IEA, GO:0043410=IEA, GO:0051300=IEA, GO:0051146=IEA, GO:0005096=TAS} apoptotic process, blastocyst development, muscle cell differentiation, negative regulation of apoptotic process, positive regulation of GTPase activity, positive regulation of MAPK cascade, positive regulation of muscle cell differentiation, positive regulation of neuron differentiation, positive regulation of small GTPase mediated signal transduction, spindle pole body organization, striated muscle cell differentiation centriole, cytoplasm, cytosol, intracellular membrane-bounded organelle, nuclear envelope, perinuclear region of cytoplasm, spindle pole centrosome GTPase activator activity, calcium ion binding, protein binding Human BNIP3 BHF-UCL UniProtKB {GO:0005515=PMID:19060904, GO:0008219=PMID:10891486, GO:0048102=GO_REF:0000019, GO:0070301=GO_REF:0000019, GO:0005741=PMID:22292033, GO:0005634=GO_REF:0000052, GO:0005635=PMID:7954800, GO:0005740=GO_REF:0000002, GO:0090141=PMID:20436456, GO:0051402=GO_REF:0000024, GO:0042803=PMID:9396766, GO:0030425=GO_REF:0000024, GO:0042802=PMID:16189514, GO:0005739=GO_REF:0000052, GO:0051607=PMID:9973195, GO:0005737=GO_REF:0000024, GO:0043243=PMID:20436456, GO:0071279=PMID:20436456, GO:0090200=PMID:20436456, GO:0006338=PMID:10891486, GO:0001666=GO_REF:0000024, GO:0046902=PMID:10891486, GO:0043066=PMID:7954800, GO:0043065=GO_REF:0000002, GO:0031966=PMID:9396766, GO:0046982=PMID:10381623, GO:0072593=PMID:10891486, GO:0071456=PMID:20436456, GO:0035694=PMID:22292033, GO:0006915=PMID:7954800, GO:0006917=PMID:9396766, GO:0043653=PMID:20436456, GO:0097193=GO_REF:0000019, GO:0051020=PMID:20436456, GO:0010637=PMID:20436456, GO:0045837=PMID:10891486, GO:0050873=GO_REF:0000019, GO:0006309=PMID:10891486, GO:0019048=GO_REF:0000037, GO:0055093=GO_REF:0000019, GO:0005654=GO_REF:0000024, GO:0016021=GO_REF:0000002, GO:0031307=PMID:10891486, GO:0071260=PMID:19593445} Q12983 BCL2/adenovirus E1B 19 kDa protein-interacting protein 3 protein 20110404 {GO:0005515=IPI, GO:0008219=IDA, GO:0048102=IEA, GO:0070301=IEA, GO:0005741=IDA, GO:0005634=IDA, GO:0005635=IDA, GO:0005740=IEA, GO:0090141=IDA, GO:0051402=ISS, GO:0042803=IDA, GO:0030425=ISS, GO:0042802=IPI, GO:0005739=IDA, GO:0051607=IDA, GO:0005737=ISS, GO:0043243=IDA, GO:0071279=IMP, GO:0090200=IDA, GO:0006338=IDA, GO:0001666=ISS, GO:0046902=IDA, GO:0043066=TAS, GO:0043065=IEA, GO:0031966=IMP, GO:0046982=IDA, GO:0072593=IDA, GO:0071456=IMP, GO:0035694=IMP, GO:0006915=IPI, GO:0006917=IDA, GO:0043653=IDA, GO:0097193=IEA, GO:0051020=IPI, GO:0010637=IDA, GO:0045837=IDA, GO:0050873=IEA, GO:0006309=IDA, GO:0019048=IEA, GO:0055093=IEA, GO:0005654=ISS, GO:0016021=IEA, GO:0031307=IDA, GO:0071260=IEP} apoptotic DNA fragmentation, apoptotic process, autophagic cell death, brown fat cell differentiation, cell death, cellular response to cobalt ion, cellular response to hydrogen peroxide, cellular response to hypoxia, cellular response to mechanical stimulus, chromatin remodeling, defense response to virus, induction of apoptosis, intrinsic apoptotic signaling pathway, mitochondrial fragmentation involved in apoptotic process, mitochondrial protein catabolic process, negative regulation of apoptotic process, negative regulation of membrane potential, negative regulation of mitochondrial fusion, neuron apoptotic process, positive regulation of apoptotic process, positive regulation of mitochondrial fission, positive regulation of protein complex disassembly, positive regulation of release of cytochrome c from mitochondria, reactive oxygen species metabolic process, regulation of mitochondrial membrane permeability, response to hyperoxia, response to hypoxia, virus-host interaction cytoplasm, dendrite, integral to membrane, integral to mitochondrial outer membrane, mitochondrial envelope, mitochondrial membrane, mitochondrial outer membrane, mitochondrion, nuclear envelope, nucleoplasm, nucleus GTPase binding, identical protein binding, protein binding, protein heterodimerization activity, protein homodimerization activity Human UniProtKB:O60313 BNIP3L IntAct UniProtKB {GO:0005515=PMID:22645275, GO:0043066=PMID:10381623, GO:0043065=GO_REF:0000002, GO:0046982=PMID:10381623, GO:0005783=PMID:10381623, GO:0035694=PMID:21264228, GO:0006915=GO_REF:0000037, GO:0005741=PMID:21264228, GO:0031224=PMID:10381623, GO:0006917=PMID:9973195, GO:0005740=GO_REF:0000002, GO:0005635=PMID:10381623, GO:0042803=PMID:10381623, GO:0042802=PMID:16189514, GO:0005739=PMID:9973195, GO:0051607=PMID:9973195, GO:0019048=GO_REF:0000037, GO:0016021=GO_REF:0000037, GO:0005521=PMID:10381623} O60238 BCL2/adenovirus E1B 19 kDa protein-interacting protein 3-like protein 20130415 {GO:0005515=IPI, GO:0043066=IDA, GO:0043065=IEA, GO:0046982=IDA, GO:0005783=IDA, GO:0035694=IMP, GO:0006915=IEA, GO:0005741=IMP, GO:0031224=TAS, GO:0006917=IDA, GO:0005740=IEA, GO:0005635=IDA, GO:0042803=IDA, GO:0042802=IPI, GO:0005739=IDA, GO:0051607=IDA, GO:0019048=IEA, GO:0016021=IEA, GO:0005521=IDA} apoptotic process, defense response to virus, induction of apoptosis, mitochondrial protein catabolic process, negative regulation of apoptotic process, positive regulation of apoptotic process, virus-host interaction endoplasmic reticulum, integral to membrane, intrinsic to membrane, mitochondrial envelope, mitochondrial outer membrane, mitochondrion, nuclear envelope identical protein binding, lamin binding, protein binding, protein heterodimerization activity, protein homodimerization activity Human UniProtKB:O60238 BNIPL MGI UniProtKB {GO:0005515=PMID:12681488, GO:0008285=PMID:12681488, GO:0006915=PMID:12901880, GO:0005634=PMID:11741952, GO:0006917=PMID:11741952, GO:0040009=PMID:12681488, GO:0042802=PMID:12901880, GO:0005829=PMID:11741952} Q7Z465 Bcl-2/adenovirus E1B 19 kDa-interacting protein 2-like protein protein 20091109 {GO:0005515=IPI, GO:0008285=IDA, GO:0006915=IDA, GO:0005634=IDA, GO:0006917=IDA, GO:0040009=IDA, GO:0042802=IPI, GO:0005829=IDA} apoptotic process, induction of apoptosis, negative regulation of cell proliferation, regulation of growth rate cytosol, nucleus identical protein binding, protein binding Human BOC Reactome UniProtKB {GO:0042692=Reactome:REACT_21303, GO:0005515=PMID:11782431, GO:0051149=Reactome:REACT_21402, GO:0005886=Reactome:REACT_21377, GO:0007411=GO_REF:0000019, GO:0045663=GO_REF:0000024, GO:0043025=GO_REF:0000019, GO:0016021=GO_REF:0000037, GO:0007155=GO_REF:0000037, GO:0044295=GO_REF:0000019, GO:0007224=GO_REF:0000019} Q9BWV1 Brother of CDO protein 20091030 {GO:0042692=TAS, GO:0005515=IPI, GO:0051149=TAS, GO:0005886=TAS, GO:0007411=IEA, GO:0045663=ISS, GO:0043025=IEA, GO:0016021=IEA, GO:0007155=IEA, GO:0044295=IEA, GO:0007224=IEA} axon guidance, cell adhesion, muscle cell differentiation, positive regulation of muscle cell differentiation, positive regulation of myoblast differentiation, smoothened signaling pathway axonal growth cone, integral to membrane, neuronal cell body, plasma membrane protein binding Human BOD1 UniProtKB UniProtKB {GO:0007067=GO_REF:0000037, GO:0005737=GO_REF:0000037, GO:0005815=GO_REF:0000039, GO:0000777=GO_REF:0000039, GO:0051301=GO_REF:0000037} Q96IK1 Biorientation of chromosomes in cell division protein 1 protein 20130413 {GO:0007067=IEA, GO:0005737=IEA, GO:0005815=IEA, GO:0000777=IEA, GO:0051301=IEA} cell division, mitosis condensed chromosome kinetochore, cytoplasm, microtubule organizing center Human UniProtKB-SubCell:SL-0048 BOK UniProtKB UniProtKB {GO:0005515=PMID:15868100, GO:0051400=GO_REF:0000019, GO:0031966=PMID:15868100, GO:0046982=GO_REF:0000019, GO:0008283=PMID:19095301, GO:0048709=GO_REF:0000019, GO:0006919=PMID:20673843, GO:0006915=PMID:15102863, GO:0005634=PMID:19095301, GO:0006917=PMID:20673843, GO:0005739=PMID:19095301, GO:0005737=PMID:20673843, GO:0072332=PMID:15102863, GO:0007420=GO_REF:0000019, GO:0008584=GO_REF:0000019} Q9UMX3 Bcl-2-related ovarian killer protein protein 20110328 {GO:0005515=IPI, GO:0051400=IEA, GO:0031966=IDA, GO:0046982=IEA, GO:0008283=IEP, GO:0048709=IEA, GO:0006919=IMP, GO:0006915=IDA, GO:0005634=IDA, GO:0006917=IMP, GO:0005739=IDA, GO:0005737=IDA, GO:0072332=IMP, GO:0007420=IEA, GO:0008584=IEA} activation of cysteine-type endopeptidase activity involved in apoptotic process, apoptotic process, brain development, cell proliferation, induction of apoptosis, intrinsic apoptotic signaling pathway by p53 class mediator, male gonad development, oligodendrocyte differentiation cytoplasm, mitochondrial membrane, mitochondrion, nucleus BH domain binding, protein binding, protein heterodimerization activity Human BOLA1 UniProtKB UniProtKB {GO:0005739=GO_REF:0000019, GO:0005576=GO_REF:0000039} Q9Y3E2 BolA-like protein 1 protein 20130413 {GO:0005739=IEA, GO:0005576=IEA} extracellular region, mitochondrion Human UniProtKB-SubCell:SL-0243 BOLA2 null null {} null null null null {} null null null BOLA2B null null {} null null null null {} null null null BOLL MGI UniProtKB {GO:0005515=PMID:16001084, GO:0005737=PMID:11390979, GO:0007126=PMID:12499397, GO:0000166=GO_REF:0000002, GO:0003723=GO_REF:0000037, GO:0045948=PMID:16001084, GO:0008494=PMID:16001084, GO:0007275=GO_REF:0000037, GO:0007283=GO_REF:0000037, GO:0003676=GO_REF:0000002, GO:0030154=GO_REF:0000037} Q8N9W6 Protein boule-like protein 20060110 {GO:0005515=IPI, GO:0005737=IDA, GO:0007126=IDA, GO:0000166=IEA, GO:0003723=IEA, GO:0045948=IDA, GO:0008494=IDA, GO:0007275=IEA, GO:0007283=IEA, GO:0003676=IEA, GO:0030154=IEA} cell differentiation, meiosis, multicellular organismal development, positive regulation of translational initiation, spermatogenesis cytoplasm RNA binding, nucleic acid binding, nucleotide binding, protein binding, translation activator activity Human BOP1 IntAct UniProtKB {GO:0005515=PMID:16043514, GO:0070545=PMID:16738141, GO:0000463=PMID:17353269, GO:0008283=PMID:16043514, GO:0030529=PMID:18809582, GO:0042254=PMID:16043514, GO:0006364=GO_REF:0000002, GO:0051726=PMID:16043514, GO:0005654=GO_REF:0000039} Q14137 Ribosome biogenesis protein BOP1 protein 20130415 {GO:0005515=IPI, GO:0070545=IDA, GO:0000463=IMP, GO:0008283=NAS, GO:0030529=IDA, GO:0042254=NAS, GO:0006364=IEA, GO:0051726=IMP, GO:0005654=IEA} cell proliferation, maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA), rRNA processing, regulation of cell cycle, ribosome biogenesis PeBoW complex, nucleoplasm, ribonucleoprotein complex protein binding Human UniProtKB:Q9GZL7 BORA UniProtKB UniProtKB {GO:0032880=PMID:18521620, GO:0005515=PMID:18521620, GO:0007088=PMID:18521620, GO:0007067=GO_REF:0000037, GO:0019901=PMID:18615013, GO:0060236=PMID:18521620, GO:0051301=GO_REF:0000037} Q6PGQ7 Protein aurora borealis protein 20100301 {GO:0032880=IMP, GO:0005515=IPI, GO:0007088=IMP, GO:0007067=IEA, GO:0019901=IPI, GO:0060236=IMP, GO:0051301=IEA} cell division, mitosis, regulation of mitosis, regulation of mitotic spindle organization, regulation of protein localization protein binding, protein kinase binding Human UniProtKB:P53350 BPGM PINC UniProtKB {GO:0007585=PMID:2542247, GO:0004082=GO_REF:0000003, GO:0005975=PMID:2542247, GO:0004083=GO_REF:0000003, GO:0004619=GO_REF:0000003, GO:0006096=GO_REF:0000037} P07738 Bisphosphoglycerate mutase protein 20030904 {GO:0007585=TAS, GO:0004082=IEA, GO:0005975=NAS, GO:0004083=IEA, GO:0004619=IEA, GO:0006096=IEA} carbohydrate metabolic process, glycolysis, respiratory gaseous exchange bisphosphoglycerate 2-phosphatase activity, bisphosphoglycerate mutase activity, phosphoglycerate mutase activity Human BPHL PINC UniProtKB {GO:0005739=GO_REF:0000024, GO:0006520=PMID:7759552, GO:0016787=GO_REF:0000037, GO:0009636=PMID:7759552} Q86WA6 Valacyclovir hydrolase protein 20050308 {GO:0005739=ISS, GO:0006520=TAS, GO:0016787=IEA, GO:0009636=TAS} cellular amino acid metabolic process, response to toxic substance mitochondrion hydrolase activity Human BPI BHF-UCL UniProtKB {GO:0001530=PMID:8409400, GO:0051636=GO_REF:0000019, GO:0006955=GO_REF:0000019, GO:0005737=GO_REF:0000019, GO:0032717=PMID:8409400, GO:0032715=PMID:8409400, GO:0005887=PMID:2722846, GO:0043031=PMID:8409400, GO:0032720=PMID:8409400, GO:0005576=GO_REF:0000039, GO:0042742=GO_REF:0000019, GO:0008289=GO_REF:0000002} P17213 Bactericidal permeability-increasing protein protein 20080707 {GO:0001530=IDA, GO:0051636=IEA, GO:0006955=IEA, GO:0005737=IEA, GO:0032717=IDA, GO:0032715=IDA, GO:0005887=TAS, GO:0043031=IDA, GO:0032720=IDA, GO:0005576=IEA, GO:0042742=IEA, GO:0008289=IEA} defense response to bacterium, immune response, negative regulation of interleukin-6 production, negative regulation of interleukin-8 production, negative regulation of macrophage activation, negative regulation of tumor necrosis factor production cytoplasm, extracellular region, integral to plasma membrane Gram-negative bacterial cell surface binding, lipid binding, lipopolysaccharide binding Human BPIFA1 UniProtKB UniProtKB {GO:0003674=GO_REF:0000015, GO:0045087=PMID:11971875, GO:0005576=PMID:11425234, GO:0008289=GO_REF:0000002} Q9NP55 BPI fold-containing family A member 1 protein 20061026 {GO:0003674=ND, GO:0045087=NAS, GO:0005576=IDA, GO:0008289=IEA} innate immune response extracellular region lipid binding, molecular_function Human BPIFB1 InterPro UniProtKB {GO:0005615=GO_REF:0000002, GO:0008289=GO_REF:0000002} Q8TDL5 BPI fold-containing family B member 1 protein 20130413 {GO:0005615=IEA, GO:0008289=IEA} extracellular space lipid binding Human InterPro:IPR001124|InterPro:IPR017942|InterPro:IPR017943 BPIFB3 UniProtKB UniProtKB {GO:0005737=PMID:12837268, GO:0045087=PMID:11971875, GO:0005576=GO_REF:0000039, GO:0008289=GO_REF:0000002} P59826 BPI fold-containing family B member 3 protein 20051025 {GO:0005737=IDA, GO:0045087=NAS, GO:0005576=IEA, GO:0008289=IEA} innate immune response cytoplasm, extracellular region lipid binding Human BPNT1 Reactome UniProtKB {GO:0046854=GO_REF:0000002, GO:0006139=PMID:10224133, GO:0006805=Reactome:REACT_13433, GO:0008441=GO_REF:0000003, GO:0000287=GO_REF:0000019, GO:0050427=Reactome:REACT_6913, GO:0044281=Reactome:REACT_111217, GO:0005829=Reactome:REACT_6763, GO:0007399=PMID:10224133, GO:0004441=GO_REF:0000019} O95861 3'(2'),5'-bisphosphate nucleotidase 1 protein 20130301 {GO:0046854=IEA, GO:0006139=TAS, GO:0006805=TAS, GO:0008441=IEA, GO:0000287=IEA, GO:0050427=TAS, GO:0044281=TAS, GO:0005829=TAS, GO:0007399=TAS, GO:0004441=IEA} 3'-phosphoadenosine 5'-phosphosulfate metabolic process, nervous system development, nucleobase-containing compound metabolic process, phosphatidylinositol phosphorylation, small molecule metabolic process, xenobiotic metabolic process cytosol 3'(2'),5'-bisphosphate nucleotidase activity, inositol-1,4-bisphosphate 1-phosphatase activity, magnesium ion binding Human BPTF HPA UniProtKB {GO:0005515=PMID:21596426, GO:0006355=PMID:10575013, GO:0005730=GO_REF:0000052, GO:0001892=GO_REF:0000019, GO:0005634=GO_REF:0000052, GO:0000122=PMID:10727212, GO:0009952=GO_REF:0000019, GO:0006351=PMID:14609955, GO:0043565=PMID:10575013, GO:0005737=GO_REF:0000039, GO:0007492=GO_REF:0000019, GO:0007420=PMID:14609955, GO:0008270=GO_REF:0000002, GO:0006338=PMID:14609955, GO:0045893=PMID:14609955, GO:0016589=PMID:20850016, GO:0008134=PMID:10727212, GO:0008094=PMID:14609955} Q12830 Nucleosome-remodeling factor subunit BPTF protein 20101115 {GO:0005515=IPI, GO:0006355=IMP, GO:0005730=IDA, GO:0001892=IEA, GO:0005634=IDA, GO:0000122=IDA, GO:0009952=IEA, GO:0006351=IMP, GO:0043565=IMP, GO:0005737=IEA, GO:0007492=IEA, GO:0007420=IMP, GO:0008270=IEA, GO:0006338=IDA, GO:0045893=IMP, GO:0016589=IDA, GO:0008134=IDA, GO:0008094=IDA} anterior/posterior pattern specification, brain development, chromatin remodeling, embryonic placenta development, endoderm development, negative regulation of transcription from RNA polymerase II promoter, positive regulation of transcription, DNA-dependent, regulation of transcription, DNA-dependent, transcription, DNA-dependent NURF complex, cytoplasm, nucleolus, nucleus DNA-dependent ATPase activity, protein binding, sequence-specific DNA binding, transcription factor binding, zinc ion binding NOT Human BPY2 IntAct UniProtKB {GO:0005515=PMID:14627543, GO:0007338=PMID:9381176, GO:0032399=PMID:12207887, GO:0005634=PMID:12724276, GO:0007283=PMID:12724276} O14599 Testis-specific basic protein Y 2 protein 20130415 {GO:0005515=IPI, GO:0007338=TAS, GO:0032399=IPI, GO:0005634=IDA, GO:0007283=IMP} single fertilization, spermatogenesis nucleus HECT domain binding, protein binding Human UniProtKB:Q66K74 BPY2B null null {} null null null null {} null null null BPY2C null null {} null null null null {} null null null BRAF BHF-UCL UniProtKB {GO:0005515=PMID:17563371, GO:0048011=Reactome:REACT_11061, GO:0043066=PMID:19667065, GO:0005886=Reactome:REACT_20578, GO:0007264=Reactome:REACT_12077, GO:0005509=PMID:18567582, GO:0007268=Reactome:REACT_13685, GO:0005634=GO_REF:0000039, GO:0005524=GO_REF:0000037, GO:0005829=Reactome:REACT_111121, GO:0010628=PMID:22065586, GO:0033138=PMID:19667065, GO:0000186=Reactome:REACT_12005, GO:0004672=PMID:17563371, GO:0008543=Reactome:REACT_9470, GO:0004674=PMID:19667065, GO:0009887=PMID:9207797, GO:0006468=PMID:17563371, GO:0070374=PMID:22065586, GO:0005057=GO_REF:0000002} P15056 Serine/threonine-protein kinase B-raf protein 20120621 {GO:0005515=IPI, GO:0048011=TAS, GO:0043066=IDA, GO:0005886=TAS, GO:0007264=TAS, GO:0005509=IDA, GO:0007268=TAS, GO:0005634=IEA, GO:0005524=IEA, GO:0005829=TAS, GO:0010628=IMP, GO:0033138=IDA, GO:0000186=TAS, GO:0004672=IDA, GO:0008543=TAS, GO:0004674=IDA, GO:0009887=TAS, GO:0006468=IDA, GO:0070374=IDA, GO:0005057=IEA} activation of MAPKK activity, fibroblast growth factor receptor signaling pathway, negative regulation of apoptotic process, neurotrophin TRK receptor signaling pathway, organ morphogenesis, positive regulation of ERK1 and ERK2 cascade, positive regulation of gene expression, positive regulation of peptidyl-serine phosphorylation, protein phosphorylation, small GTPase mediated signal transduction, synaptic transmission cytosol, nucleus, plasma membrane ATP binding, calcium ion binding, protein binding, protein kinase activity, protein serine/threonine kinase activity, receptor signaling protein activity Human BRAP IntAct UniProtKB {GO:0005515=PMID:14724641, GO:0005737=PMID:9497340, GO:0004842=PMID:14724641, GO:0000166=GO_REF:0000002, GO:0000165=PMID:14724641, GO:0000151=PMID:14724641, GO:0008139=PMID:9497340, GO:0007265=PMID:14724641, GO:0008270=GO_REF:0000002, GO:0009968=PMID:14724641} Q7Z569 BRCA1-associated protein protein 20130415 {GO:0005515=IPI, GO:0005737=IDA, GO:0004842=IDA, GO:0000166=IEA, GO:0000165=IDA, GO:0000151=IDA, GO:0008139=IDA, GO:0007265=IDA, GO:0008270=IEA, GO:0009968=IDA} MAPK cascade, Ras protein signal transduction, negative regulation of signal transduction cytoplasm, ubiquitin ligase complex nuclear localization sequence binding, nucleotide binding, protein binding, ubiquitin-protein ligase activity, zinc ion binding Human UniProtKB:P01112 BRAT1 UniProtKB UniProtKB {GO:0005515=PMID:16452482, GO:0010212=PMID:16452482, GO:0005634=PMID:16452482} Q6PJG6 BRCA1-associated ATM activator 1 protein 20100510 {GO:0005515=IPI, GO:0010212=IMP, GO:0005634=IDA} response to ionizing radiation nucleus protein binding Human UniProtKB:P38398 BRCA1 ENSEMBL UniProtKB {GO:0005515=PMID:21282464, GO:0004842=PMID:17349954, GO:0043627=PMID:8895509, GO:0044212=GO_REF:0000019, GO:2000145=PMID:21282464, GO:0009048=GO_REF:0000019, GO:0050681=PMID:15572661, GO:0071158=PMID:21102443, GO:2000617=GO_REF:0000019, GO:0070531=PMID:19261749, GO:0042127=PMID:10918303, GO:0044030=GO_REF:0000019, GO:0031398=PMID:15965487, GO:0034446=PMID:21282464, GO:0006978=PMID:10918303, GO:0031625=PMID:17873885, GO:0085020=PMID:12890688, GO:0005694=GO_REF:0000024, GO:0003713=PMID:15572661, GO:0031436=PMID:19117993, GO:0046600=PMID:12214252, GO:0051865=PMID:12890688, GO:0043234=PMID:9774970, GO:0006281=GO_REF:0000002, GO:0005654=Reactome:REACT_21405, GO:0008270=GO_REF:0000002, GO:2000620=GO_REF:0000019, GO:0045893=PMID:15572661, GO:0019899=PMID:15965487, GO:0005925=PMID:21282464, GO:0045892=PMID:16288014, GO:0008274=PMID:12214252, GO:0016567=PMID:17349954, GO:0005886=PMID:21282464, GO:0007098=GO_REF:0000019, GO:0003723=PMID:12419249, GO:0031572=PMID:19261748, GO:0000151=PMID:14976165, GO:0005634=PMID:17643121, GO:0045739=PMID:19261748, GO:0035067=GO_REF:0000019, GO:0035066=PMID:20820192, GO:0043009=GO_REF:0000019, GO:0006301=PMID:17349954, GO:0006302=Reactome:REACT_2054, GO:0071681=PMID:10868478, GO:0005737=GO_REF:0000019, GO:0007059=PMID:15965487, GO:0015631=PMID:12214252, GO:0000724=Reactome:REACT_1874, GO:0045944=GO_REF:0000019, GO:0010212=PMID:19261748, GO:0070512=GO_REF:0000019, GO:0006633=GO_REF:0000037, GO:0000794=GO_REF:0000019, GO:0008630=PMID:14654789, GO:0006357=PMID:10910365, GO:0006359=PMID:10918303, GO:0045717=PMID:16326698, GO:0006915=PMID:10918303, GO:0042981=PMID:10918303, GO:0001726=PMID:21282464, GO:0003677=PMID:9662397, GO:0006974=PMID:10910365, GO:0003684=GO_REF:0000019, GO:0006260=GO_REF:0000019, GO:0051574=GO_REF:0000019, GO:0031941=PMID:21282464, GO:0051571=GO_REF:0000019, GO:0030529=PMID:18809582, GO:0051573=GO_REF:0000019, GO:0051572=GO_REF:0000019, GO:0006349=GO_REF:0000019, GO:0030521=PMID:15572661} Q3B891 Breast cancer type 1 susceptibility protein protein 20130413 {GO:0005515=IPI, GO:0004842=IDA, GO:0043627=IDA, GO:0044212=IEA, GO:2000145=IDA, GO:0009048=IEA, GO:0050681=NAS, GO:0071158=IDA, GO:2000617=IEA, GO:0070531=IDA, GO:0042127=TAS, GO:0044030=IEA, GO:0031398=IDA, GO:0034446=IDA, GO:0006978=TAS, GO:0031625=IPI, GO:0085020=IDA, GO:0005694=ISS, GO:0003713=NAS, GO:0031436=IDA, GO:0046600=NAS, GO:0051865=IDA, GO:0043234=IDA, GO:0006281=IEA, GO:0005654=TAS, GO:0008270=IEA, GO:2000620=IEA, GO:0045893=NAS, GO:0019899=IPI, GO:0005925=IDA, GO:0045892=IDA, GO:0008274=NAS, GO:0016567=IDA, GO:0005886=IDA, GO:0007098=IEA, GO:0003723=IDA, GO:0031572=IMP, GO:0000151=NAS, GO:0005634=IDA, GO:0045739=IMP, GO:0035067=IEA, GO:0035066=IDA, GO:0043009=IEA, GO:0006301=IDA, GO:0006302=TAS, GO:0071681=IDA, GO:0005737=IEA, GO:0007059=IMP, GO:0015631=NAS, GO:0000724=TAS, GO:0045944=IEA, GO:0010212=IMP, GO:0070512=IEA, GO:0006633=IEA, GO:0000794=IEA, GO:0008630=IDA, GO:0006357=TAS, GO:0006359=TAS, GO:0045717=IMP, GO:0006915=TAS, GO:0042981=TAS, GO:0001726=IDA, GO:0003677=TAS, GO:0006974=TAS, GO:0003684=IEA, GO:0006260=IEA, GO:0051574=IEA, GO:0031941=IDA, GO:0051571=IEA, GO:0030529=IDA, GO:0051573=IEA, GO:0051572=IEA, GO:0006349=IEA, GO:0030521=NAS} DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, DNA repair, DNA replication, G2 DNA damage checkpoint, androgen receptor signaling pathway, apoptotic process, cellular response to indole-3-methanol, centrosome cycle, chordate embryonic development, chromosome segregation, dosage compensation by inactivation of X chromosome, double-strand break repair, double-strand break repair via homologous recombination, fatty acid biosynthetic process, intrinsic apoptotic signaling pathway in response to DNA damage, negative regulation of centriole replication, negative regulation of fatty acid biosynthetic process, negative regulation of histone H3-K4 methylation, negative regulation of histone H3-K9 methylation, negative regulation of histone acetylation, negative regulation of transcription, DNA-dependent, positive regulation of DNA repair, positive regulation of cell cycle arrest, positive regulation of histone H3-K4 methylation, positive regulation of histone H3-K9 acetylation, positive regulation of histone H3-K9 methylation, positive regulation of histone H4-K16 acetylation, positive regulation of histone H4-K20 methylation, positive regulation of histone acetylation, positive regulation of protein ubiquitination, positive regulation of transcription from RNA polymerase II promoter, positive regulation of transcription, DNA-dependent, postreplication repair, protein K6-linked ubiquitination, protein autoubiquitination, protein ubiquitination, regulation of DNA methylation, regulation of apoptotic process, regulation of cell motility, regulation of cell proliferation, regulation of gene expression by genetic imprinting, regulation of transcription from RNA polymerase II promoter, regulation of transcription from RNA polymerase III promoter, response to DNA damage stimulus, response to estrogen stimulus, response to ionizing radiation, substrate adhesion-dependent cell spreading BRCA1-A complex, BRCA1-BARD1 complex, chromosome, condensed nuclear chromosome, cytoplasm, filamentous actin, focal adhesion, gamma-tubulin ring complex, nucleoplasm, nucleus, plasma membrane, protein complex, ribonucleoprotein complex, ruffle, ubiquitin ligase complex DNA binding, RNA binding, androgen receptor binding, damaged DNA binding, enzyme binding, protein binding, transcription coactivator activity, transcription regulatory region DNA binding, tubulin binding, ubiquitin protein ligase binding, ubiquitin-protein ligase activity, zinc ion binding Human Ensembl:ENSMUSP00000017290 BRCA2 HPA UniProtKB {GO:0005515=PMID:21399666, GO:0010165=GO_REF:0000019, GO:0048478=GO_REF:0000019, GO:0001833=GO_REF:0000019, GO:0005634=GO_REF:0000052, GO:0007283=GO_REF:0000019, GO:0001556=GO_REF:0000019, GO:0002020=PMID:15314155, GO:0033593=PMID:15930293, GO:0006302=Reactome:REACT_2054, GO:0005737=GO_REF:0000052, GO:0003697=PMID:20729832, GO:0000724=Reactome:REACT_1874, GO:0010485=PMID:9619837, GO:0006978=GO_REF:0000019, GO:0007090=GO_REF:0000002, GO:0030141=PMID:8589722, GO:0010332=GO_REF:0000019, GO:0004402=PMID:9824164, GO:0030097=GO_REF:0000019, GO:0005813=PMID:17286961, GO:0032465=GO_REF:0000019, GO:0043015=PMID:17286961, GO:0010484=PMID:9619837, GO:0007569=GO_REF:0000019, GO:0005730=GO_REF:0000052, GO:0008585=GO_REF:0000019, GO:0042771=GO_REF:0000019, GO:0051298=PMID:17286961, GO:0043234=PMID:9774970, GO:0010225=GO_REF:0000019, GO:0045931=GO_REF:0000019, GO:0006281=Reactome:REACT_216, GO:0043966=PMID:9619837, GO:0043967=PMID:9619837, GO:0007420=GO_REF:0000019, GO:0005654=Reactome:REACT_1612, GO:0006289=PMID:16845393, GO:0045893=PMID:9126734, GO:0033600=PMID:15930293, GO:0007141=GO_REF:0000019} P51587 Breast cancer type 2 susceptibility protein protein 20101115 {GO:0005515=IPI, GO:0010165=IEA, GO:0048478=IEA, GO:0001833=IEA, GO:0005634=IDA, GO:0007283=IEA, GO:0001556=IEA, GO:0002020=IPI, GO:0033593=IDA, GO:0006302=TAS, GO:0005737=IDA, GO:0003697=IDA, GO:0000724=TAS, GO:0010485=IDA, GO:0006978=IEA, GO:0007090=IEA, GO:0030141=IDA, GO:0010332=IEA, GO:0004402=IDA, GO:0030097=IEA, GO:0005813=IDA, GO:0032465=IEA, GO:0043015=IPI, GO:0010484=IDA, GO:0007569=IEA, GO:0005730=IDA, GO:0008585=IEA, GO:0042771=IEA, GO:0051298=IMP, GO:0043234=IDA, GO:0010225=IEA, GO:0045931=IEA, GO:0006281=TAS, GO:0043966=IDA, GO:0043967=IDA, GO:0007420=IEA, GO:0005654=TAS, GO:0006289=IMP, GO:0045893=IDA, GO:0033600=IDA, GO:0007141=IEA} DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, DNA repair, brain development, cell aging, centrosome duplication, double-strand break repair, double-strand break repair via homologous recombination, female gonad development, hemopoiesis, histone H3 acetylation, histone H4 acetylation, inner cell mass cell proliferation, intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator, male meiosis I, negative regulation of mammary gland epithelial cell proliferation, nucleotide-excision repair, oocyte maturation, positive regulation of mitotic cell cycle, positive regulation of transcription, DNA-dependent, regulation of S phase of mitotic cell cycle, regulation of cytokinesis, replication fork protection, response to UV-C, response to X-ray, response to gamma radiation, spermatogenesis BRCA2-MAGE-D1 complex, centrosome, cytoplasm, nucleolus, nucleoplasm, nucleus, protein complex, secretory granule H3 histone acetyltransferase activity, H4 histone acetyltransferase activity, gamma-tubulin binding, histone acetyltransferase activity, protease binding, protein binding, single-stranded DNA binding Human BRCC3 GOC UniProtKB {GO:0005515=PMID:14636569, GO:0004843=PMID:19261746, GO:0010165=PMID:14636569, GO:0031572=PMID:17525341, GO:0000151=PMID:14636569, GO:0005634=PMID:19202061, GO:0045739=PMID:19261746, GO:0000152=PMID:14636569, GO:0046872=GO_REF:0000037, GO:0006302=PMID:19261748, GO:0070531=PMID:19261746, GO:0050790=PMID:14636569, GO:0070552=PMID:19214193, GO:0070536=PMID:17525341, GO:0010212=PMID:19261746, GO:0070537=PMID:19202061, GO:0006508=GO_REF:0000037, GO:0030234=PMID:14636569, GO:0004221=PMID:19214193, GO:0008237=PMID:19261746, GO:0031593=PMID:19261749} P46736 Lys-63-specific deubiquitinase BRCC36 protein 20130413 {GO:0005515=IPI, GO:0004843=IMP, GO:0010165=IDA, GO:0031572=IMP, GO:0000151=IDA, GO:0005634=IDA, GO:0045739=IMP, GO:0000152=IDA, GO:0046872=IEA, GO:0006302=IMP, GO:0070531=IDA, GO:0050790=IDA, GO:0070552=IDA, GO:0070536=IDA, GO:0010212=IMP, GO:0070537=IDA, GO:0006508=IEA, GO:0030234=IDA, GO:0004221=IMP, GO:0008237=IMP, GO:0031593=IDA} G2 DNA damage checkpoint, double-strand break repair, histone H2A K63-linked deubiquitination, positive regulation of DNA repair, protein K63-linked deubiquitination, proteolysis, regulation of catalytic activity, response to X-ray, response to ionizing radiation BRCA1-A complex, BRISC complex, nuclear ubiquitin ligase complex, nucleus, ubiquitin ligase complex enzyme regulator activity, metal ion binding, metallopeptidase activity, polyubiquitin binding, protein binding, ubiquitin thiolesterase activity, ubiquitin-specific protease activity Human BRD1 HPA UniProtKB {GO:0042393=PMID:21880731, GO:0070776=PMID:16387653, GO:0043966=PMID:16387653, GO:0005634=GO_REF:0000052, GO:0008270=GO_REF:0000002} O95696 Bromodomain-containing protein 1 protein 20080205 {GO:0042393=IDA, GO:0070776=IDA, GO:0043966=IDA, GO:0005634=IDA, GO:0008270=IEA} histone H3 acetylation MOZ/MORF histone acetyltransferase complex, nucleus histone binding, zinc ion binding Human BRD2 PINC UniProtKB {GO:0005737=GO_REF:0000019, GO:0006357=PMID:18406326, GO:0003682=PMID:18406326, GO:0006334=PMID:18406326, GO:0070577=PMID:18406326, GO:0005634=GO_REF:0000039, GO:0007283=PMID:9693039, GO:0006351=GO_REF:0000037, GO:0016568=GO_REF:0000037} P25440 Bromodomain-containing protein 2 protein 20030904 {GO:0005737=IEA, GO:0006357=IDA, GO:0003682=IDA, GO:0006334=IMP, GO:0070577=IDA, GO:0005634=IEA, GO:0007283=TAS, GO:0006351=IEA, GO:0016568=IEA} chromatin modification, nucleosome assembly, regulation of transcription from RNA polymerase II promoter, spermatogenesis, transcription, DNA-dependent cytoplasm, nucleus chromatin binding, histone acetyl-lysine binding Human BRD3 IntAct UniProtKB {GO:0005515=PMID:20195357, GO:0008150=GO_REF:0000015, GO:0003674=GO_REF:0000015, GO:0006357=PMID:18406326, GO:0003682=PMID:18406326, GO:0070577=PMID:22464331, GO:0005634=GO_REF:0000029, GO:0006351=GO_REF:0000037, GO:0016568=GO_REF:0000037} Q15059 Bromodomain-containing protein 3 protein 20130415 {GO:0005515=IPI, GO:0008150=ND, GO:0003674=ND, GO:0006357=IDA, GO:0003682=IDA, GO:0070577=IDA, GO:0005634=NAS, GO:0006351=IEA, GO:0016568=IEA} biological_process, chromatin modification, regulation of transcription from RNA polymerase II promoter, transcription, DNA-dependent nucleus chromatin binding, histone acetyl-lysine binding, molecular_function, protein binding Human UniProtKB:P01106 BRD4 HPA UniProtKB {GO:0005515=PMID:17474147, GO:0000790=GO_REF:0000019, GO:0000794=PMID:10938129, GO:0001833=GO_REF:0000019, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0003677=GO_REF:0000019, GO:0005737=GO_REF:0000052, GO:0043983=GO_REF:0000019, GO:0010971=PMID:10938129, GO:0007059=GO_REF:0000019, GO:0019048=GO_REF:0000037, GO:0043388=GO_REF:0000019, GO:0000114=PMID:18039861, GO:0032968=PMID:18039861, GO:0006468=GO_REF:0000019, GO:0044154=GO_REF:0000019} O60885 Bromodomain-containing protein 4 protein 20090616 {GO:0005515=IPI, GO:0000790=IEA, GO:0000794=IDA, GO:0001833=IEA, GO:0005730=IDA, GO:0005634=IDA, GO:0003677=IEA, GO:0005737=IDA, GO:0043983=IEA, GO:0010971=IMP, GO:0007059=IEA, GO:0019048=IEA, GO:0043388=IEA, GO:0000114=IMP, GO:0032968=IMP, GO:0006468=IEA, GO:0044154=IEA} chromosome segregation, histone H3-K14 acetylation, histone H4-K12 acetylation, inner cell mass cell proliferation, positive regulation of DNA binding, positive regulation of G2/M transition of mitotic cell cycle, positive regulation of transcription elongation from RNA polymerase II promoter, protein phosphorylation, regulation of transcription involved in G1 phase of mitotic cell cycle, virus-host interaction condensed nuclear chromosome, cytoplasm, nuclear chromatin, nucleolus, nucleus DNA binding, protein binding Human BRD7 IntAct UniProtKB {GO:0005515=PMID:20228809, GO:0008285=PMID:20228809, GO:0006357=PMID:12489984, GO:0044212=PMID:20228809, GO:0003714=PMID:16265664, GO:0003713=PMID:20228809, GO:2000134=PMID:16265664, GO:0005634=PMID:12489984, GO:0035066=PMID:20228809, GO:0006351=GO_REF:0000037, GO:0042393=PMID:12489984, GO:0002039=PMID:20228809, GO:0005737=PMID:10526152, GO:0007049=GO_REF:0000037, GO:0070577=PMID:16265664, GO:0016055=GO_REF:0000037, GO:0045893=PMID:20228809, GO:0045892=PMID:16265664, GO:0008134=PMID:11025449} Q9NPI1 Bromodomain-containing protein 7 protein 20130415 {GO:0005515=IPI, GO:0008285=IDA, GO:0006357=IDA, GO:0044212=IDA, GO:0003714=IDA, GO:0003713=IDA, GO:2000134=IDA, GO:0005634=IDA, GO:0035066=IDA, GO:0006351=IEA, GO:0042393=IDA, GO:0002039=IPI, GO:0005737=TAS, GO:0007049=IEA, GO:0070577=IDA, GO:0016055=IEA, GO:0045893=IDA, GO:0045892=IDA, GO:0008134=IDA} Wnt receptor signaling pathway, cell cycle, negative regulation of G1/S transition of mitotic cell cycle, negative regulation of cell proliferation, negative regulation of transcription, DNA-dependent, positive regulation of histone acetylation, positive regulation of transcription, DNA-dependent, regulation of transcription from RNA polymerase II promoter, transcription, DNA-dependent cytoplasm, nucleus histone acetyl-lysine binding, histone binding, p53 binding, protein binding, transcription coactivator activity, transcription corepressor activity, transcription factor binding, transcription regulatory region DNA binding Human UniProtKB:Q09472 BRD8 HPA UniProtKB {GO:0006355=PMID:8611617, GO:0003700=PMID:8611617, GO:0006357=PMID:9368056, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0005739=GO_REF:0000052, GO:0007165=PMID:9368056, GO:0043967=PMID:14966270, GO:0043968=PMID:14966270, GO:0035267=PMID:14966270, GO:0004887=PMID:9368056, GO:0040008=GO_REF:0000037, GO:0007166=PMID:9368056} Q9H0E9 Bromodomain-containing protein 8 protein 20080818 {GO:0006355=NAS, GO:0003700=NAS, GO:0006357=TAS, GO:0005730=IDA, GO:0005634=IDA, GO:0005739=IDA, GO:0007165=TAS, GO:0043967=IDA, GO:0043968=IDA, GO:0035267=IDA, GO:0004887=TAS, GO:0040008=IEA, GO:0007166=TAS} cell surface receptor signaling pathway, histone H2A acetylation, histone H4 acetylation, regulation of growth, regulation of transcription from RNA polymerase II promoter, regulation of transcription, DNA-dependent, signal transduction NuA4 histone acetyltransferase complex, mitochondrion, nucleolus, nucleus sequence-specific DNA binding transcription factor activity, thyroid hormone receptor activity Human BRD9 UniProtKB UniProtKB {GO:0008150=GO_REF:0000015, GO:0006355=GO_REF:0000037, GO:0070577=PMID:22464331, GO:0005575=GO_REF:0000015, GO:0003676=PMID:18559093, GO:0006351=GO_REF:0000037, GO:0016568=GO_REF:0000037} Q9H8M2 Bromodomain-containing protein 9 protein 20120706 {GO:0008150=ND, GO:0006355=IEA, GO:0070577=IDA, GO:0005575=ND, GO:0003676=NAS, GO:0006351=IEA, GO:0016568=IEA} biological_process, chromatin modification, regulation of transcription, DNA-dependent, transcription, DNA-dependent cellular_component histone acetyl-lysine binding, nucleic acid binding Human BRDT UniProtKB UniProtKB {GO:0006397=GO_REF:0000037, GO:0008380=GO_REF:0000037, GO:0003713=PMID:10365964, GO:0005634=GO_REF:0000024, GO:0001207=GO_REF:0000024, GO:0007283=GO_REF:0000024, GO:0006351=GO_REF:0000037, GO:0030154=GO_REF:0000037, GO:0042393=PMID:22464331, GO:0051039=GO_REF:0000024, GO:0070577=GO_REF:0000024, GO:0006338=GO_REF:0000024, GO:0043484=GO_REF:0000024, GO:0007141=GO_REF:0000024, GO:0007140=GO_REF:0000024} Q58F21 Bromodomain testis-specific protein protein 20121022 {GO:0006397=IEA, GO:0008380=IEA, GO:0003713=TAS, GO:0005634=ISS, GO:0001207=ISS, GO:0007283=ISS, GO:0006351=IEA, GO:0030154=IEA, GO:0042393=IDA, GO:0051039=ISS, GO:0070577=ISS, GO:0006338=ISS, GO:0043484=ISS, GO:0007141=ISS, GO:0007140=ISS} RNA splicing, cell differentiation, chromatin remodeling, histone displacement, mRNA processing, male meiosis, male meiosis I, positive regulation of transcription during meiosis, regulation of RNA splicing, spermatogenesis, transcription, DNA-dependent nucleus histone acetyl-lysine binding, histone binding, transcription coactivator activity Human UniProtKB:Q91Y44 BRE HPA UniProtKB {GO:0005515=PMID:19615732, GO:0005164=PMID:15465831, GO:0000268=PMID:11676476, GO:0031572=PMID:19261748, GO:0006915=GO_REF:0000037, GO:0005634=PMID:15465831, GO:0045739=PMID:19261748, GO:0000152=PMID:14636569, GO:0006974=PMID:7826398, GO:0006302=PMID:19261748, GO:0007165=PMID:9737713, GO:0070531=PMID:19261746, GO:0005737=GO_REF:0000052, GO:0070552=PMID:19214193, GO:0010212=PMID:19261749, GO:0016568=GO_REF:0000037, GO:0031593=PMID:19261749} Q9NXR7 BRCA1-A complex subunit BRE protein 20100326 {GO:0005515=IPI, GO:0005164=IDA, GO:0000268=TAS, GO:0031572=IMP, GO:0006915=IEA, GO:0005634=IDA, GO:0045739=IMP, GO:0000152=IDA, GO:0006974=IEP, GO:0006302=IMP, GO:0007165=TAS, GO:0070531=IDA, GO:0005737=IDA, GO:0070552=IDA, GO:0010212=IMP, GO:0016568=IEA, GO:0031593=IDA} G2 DNA damage checkpoint, apoptotic process, chromatin modification, double-strand break repair, positive regulation of DNA repair, response to DNA damage stimulus, response to ionizing radiation, signal transduction BRCA1-A complex, BRISC complex, cytoplasm, nuclear ubiquitin ligase complex, nucleus peroxisome targeting sequence binding, polyubiquitin binding, protein binding, tumor necrosis factor receptor binding Human BRF1 Reactome UniProtKB {GO:0010467=Reactome:REACT_71, GO:0006352=GO_REF:0000002, GO:0043488=GO_REF:0000019, GO:0009304=PMID:8943358, GO:0006355=GO_REF:0000002, GO:0009303=PMID:7624363, GO:0005634=GO_REF:0000002, GO:0006384=PMID:7624363, GO:0006383=Reactome:REACT_1371, GO:0000126=PMID:8943358, GO:0017025=GO_REF:0000002, GO:0008270=GO_REF:0000002, GO:0005654=Reactome:REACT_1779, GO:0045893=GO_REF:0000002} Q92994 Transcription factor IIIB 90 kDa subunit protein 20130213 {GO:0010467=TAS, GO:0006352=IEA, GO:0043488=IEA, GO:0009304=TAS, GO:0006355=IEA, GO:0009303=TAS, GO:0005634=IEA, GO:0006384=TAS, GO:0006383=TAS, GO:0000126=NAS, GO:0017025=IEA, GO:0008270=IEA, GO:0005654=TAS, GO:0045893=IEA} DNA-dependent transcription, initiation, gene expression, positive regulation of transcription, DNA-dependent, rRNA transcription, regulation of mRNA stability, regulation of transcription, DNA-dependent, tRNA transcription, transcription from RNA polymerase III promoter, transcription initiation from RNA polymerase III promoter nucleoplasm, nucleus, transcription factor TFIIIB complex TBP-class protein binding, zinc ion binding Human BRF2 Reactome UniProtKB {GO:0010467=Reactome:REACT_71, GO:0006352=GO_REF:0000002, GO:0006355=GO_REF:0000037, GO:0005654=Reactome:REACT_328, GO:0008270=GO_REF:0000002, GO:0006383=Reactome:REACT_1371} Q9HAW0 Transcription factor IIIB 50 kDa subunit protein 20130213 {GO:0010467=TAS, GO:0006352=IEA, GO:0006355=IEA, GO:0005654=TAS, GO:0008270=IEA, GO:0006383=TAS} DNA-dependent transcription, initiation, gene expression, regulation of transcription, DNA-dependent, transcription from RNA polymerase III promoter nucleoplasm zinc ion binding Human BRI3 UniProtKB UniProtKB {GO:0016021=GO_REF:0000037} O95415 Brain protein I3 protein 20130413 {GO:0016021=IEA} integral to membrane Human UniProtKB-KW:KW-0812 BRI3BP UniProtKB UniProtKB {GO:0005741=GO_REF:0000039, GO:0016021=GO_REF:0000037} Q8WY22 BRI3-binding protein protein 20130413 {GO:0005741=IEA, GO:0016021=IEA} integral to membrane, mitochondrial outer membrane Human UniProtKB-SubCell:SL-0172 BRIP1 HPA UniProtKB {GO:0008026=GO_REF:0000002, GO:0005515=PMID:17525340, GO:0031965=GO_REF:0000052, GO:0016817=GO_REF:0000002, GO:0051539=GO_REF:0000037, GO:0006357=PMID:14504288, GO:0005634=GO_REF:0000052, GO:0044281=Reactome:REACT_111217, GO:0003676=GO_REF:0000002, GO:0005524=GO_REF:0000037, GO:0003677=PMID:15878853, GO:0046872=GO_REF:0000037, GO:0006302=PMID:11301010, GO:0005737=PMID:14504288, GO:0004003=PMID:11301010, GO:0000077=PMID:14576433} Q9BX63 Fanconi anemia group J protein protein 20090616 {GO:0008026=IEA, GO:0005515=IPI, GO:0031965=IDA, GO:0016817=IEA, GO:0051539=IEA, GO:0006357=IDA, GO:0005634=IDA, GO:0044281=TAS, GO:0003676=IEA, GO:0005524=IEA, GO:0003677=NAS, GO:0046872=IEA, GO:0006302=NAS, GO:0005737=IDA, GO:0004003=NAS, GO:0000077=NAS} DNA damage checkpoint, double-strand break repair, regulation of transcription from RNA polymerase II promoter, small molecule metabolic process cytoplasm, nuclear membrane, nucleus 4 iron, 4 sulfur cluster binding, ATP binding, ATP-dependent DNA helicase activity, ATP-dependent helicase activity, DNA binding, hydrolase activity, acting on acid anhydrides, metal ion binding, nucleic acid binding, protein binding Human BRIX1 HPA UniProtKB {GO:0003674=GO_REF:0000015, GO:0042254=GO_REF:0000037, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052} Q8TDN6 Ribosome biogenesis protein BRX1 homolog protein 20110516 {GO:0003674=ND, GO:0042254=IEA, GO:0005730=IDA, GO:0005634=IDA} ribosome biogenesis nucleolus, nucleus molecular_function Human BRK1 Reactome UniProtKB {GO:0008284=GO_REF:0000019, GO:0030036=GO_REF:0000019, GO:0045087=Reactome:REACT_6802, GO:0048870=GO_REF:0000019, GO:0005856=GO_REF:0000039, GO:0038096=Reactome:REACT_160123, GO:0001701=GO_REF:0000019, GO:0005829=Reactome:REACT_160291} Q8WUW1 Protein BRICK1 protein 20111015 {GO:0008284=IEA, GO:0030036=IEA, GO:0045087=TAS, GO:0048870=IEA, GO:0005856=IEA, GO:0038096=TAS, GO:0001701=IEA, GO:0005829=TAS} Fc-gamma receptor signaling pathway involved in phagocytosis, actin cytoskeleton organization, cell motility, in utero embryonic development, innate immune response, positive regulation of cell proliferation cytoskeleton, cytosol Human BRMS1 IntAct UniProtKB {GO:0005515=PMID:21258344, GO:0005737=PMID:20830743, GO:0051059=PMID:17000776, GO:0009987=GO_REF:0000019, GO:2000210=PMID:17000776, GO:0006915=GO_REF:0000037, GO:0032088=PMID:17000776, GO:0005634=PMID:17000776, GO:0045892=PMID:20830743, GO:0006351=GO_REF:0000037, GO:0090312=PMID:17000776} Q9HCU9 Breast cancer metastasis-suppressor 1 protein 20130415 {GO:0005515=IPI, GO:0005737=IDA, GO:0051059=IDA, GO:0009987=IEA, GO:2000210=IMP, GO:0006915=IEA, GO:0032088=IDA, GO:0005634=IDA, GO:0045892=IDA, GO:0006351=IEA, GO:0090312=IDA} apoptotic process, cellular process, negative regulation of NF-kappaB transcription factor activity, negative regulation of transcription, DNA-dependent, positive regulation of anoikis, positive regulation of protein deacetylation, transcription, DNA-dependent cytoplasm, nucleus NF-kappaB binding, protein binding Human UniProtKB:Q92769 BRMS1L UniProtKB UniProtKB {GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0040008=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q5PSV4 Breast cancer metastasis-suppressor 1-like protein protein 20130413 {GO:0006355=IEA, GO:0005634=IEA, GO:0040008=IEA, GO:0006351=IEA} regulation of growth, regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus Human UniProtKB-SubCell:SL-0191 BROX UniProtKB UniProtKB {GO:0016020=GO_REF:0000039} Q5VW32 BRO1 domain-containing protein BROX protein 20130413 {GO:0016020=IEA} membrane Human UniProtKB-SubCell:SL-0162 BRPF1 HPA UniProtKB {GO:0005737=GO_REF:0000052, GO:0070776=PMID:18794358, GO:0005886=GO_REF:0000052, GO:0043966=PMID:16387653, GO:0005634=PMID:18794358, GO:0008270=GO_REF:0000002, GO:0045893=PMID:18794358, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} P55201 Peregrin protein 20101115 {GO:0005737=IDA, GO:0070776=IDA, GO:0005886=IDA, GO:0043966=IDA, GO:0005634=IDA, GO:0008270=IEA, GO:0045893=IDA, GO:0003677=IEA, GO:0006351=IEA} histone H3 acetylation, positive regulation of transcription, DNA-dependent, transcription, DNA-dependent MOZ/MORF histone acetyltransferase complex, cytoplasm, nucleus, plasma membrane DNA binding, zinc ion binding Human BRPF3 IntAct UniProtKB {GO:0005515=PMID:17474147, GO:0070776=PMID:16387653, GO:0043966=PMID:16387653, GO:0007596=Reactome:REACT_604, GO:0002576=Reactome:REACT_318, GO:0030168=Reactome:REACT_798, GO:0005576=Reactome:REACT_21347, GO:0008270=GO_REF:0000002, GO:0005829=Reactome:REACT_21347} Q9ULD4 Bromodomain and PHD finger-containing protein 3 protein 20130415 {GO:0005515=IPI, GO:0070776=IDA, GO:0043966=IDA, GO:0007596=TAS, GO:0002576=TAS, GO:0030168=TAS, GO:0005576=TAS, GO:0008270=IEA, GO:0005829=TAS} blood coagulation, histone H3 acetylation, platelet activation, platelet degranulation MOZ/MORF histone acetyltransferase complex, cytosol, extracellular region protein binding, zinc ion binding Human UniProtKB:P16333 BRSK1 HPA UniProtKB {GO:0005813=GO_REF:0000024, GO:0030054=GO_REF:0000052, GO:0000287=PMID:14976552, GO:0005886=GO_REF:0000052, GO:0019901=GO_REF:0000019, GO:0043015=GO_REF:0000024, GO:0031572=PMID:15150265, GO:0005730=GO_REF:0000052, GO:0050321=PMID:21985311, GO:0005634=GO_REF:0000052, GO:0030010=GO_REF:0000024, GO:0007409=GO_REF:0000024, GO:0005524=PMID:15150265, GO:0006974=PMID:15150265, GO:0007269=GO_REF:0000024, GO:0008021=GO_REF:0000024, GO:0051298=GO_REF:0000024, GO:0005737=PMID:15150265, GO:0004672=GO_REF:0000002, GO:0004674=PMID:15150265, GO:0010212=PMID:15150265, GO:0030182=GO_REF:0000024, GO:0006468=PMID:15150265, GO:0009411=PMID:15150265} Q8TDC3 Serine/threonine-protein kinase BRSK1 protein 20101115 {GO:0005813=ISS, GO:0030054=IDA, GO:0000287=IDA, GO:0005886=IDA, GO:0019901=IEA, GO:0043015=ISS, GO:0031572=IDA, GO:0005730=IDA, GO:0050321=IDA, GO:0005634=IDA, GO:0030010=ISS, GO:0007409=ISS, GO:0005524=IC, GO:0006974=IDA, GO:0007269=ISS, GO:0008021=ISS, GO:0051298=ISS, GO:0005737=IDA, GO:0004672=IEA, GO:0004674=IDA, GO:0010212=IDA, GO:0030182=ISS, GO:0006468=IDA, GO:0009411=IDA} G2 DNA damage checkpoint, axonogenesis, centrosome duplication, establishment of cell polarity, neuron differentiation, neurotransmitter secretion, protein phosphorylation, response to DNA damage stimulus, response to UV, response to ionizing radiation cell junction, centrosome, cytoplasm, nucleolus, nucleus, plasma membrane, synaptic vesicle ATP binding, gamma-tubulin binding, magnesium ion binding, protein kinase activity, protein kinase binding, protein serine/threonine kinase activity, tau-protein kinase activity Human BRSK2 UniProtKB UniProtKB {GO:0005813=PMID:23029325, GO:0048471=GO_REF:0000039, GO:0000287=PMID:14976552, GO:0031532=PMID:22669945, GO:0019901=GO_REF:0000019, GO:0005783=GO_REF:0000039, GO:0050321=PMID:21985311, GO:0030010=GO_REF:0000024, GO:0007409=GO_REF:0000024, GO:0006887=GO_REF:0000037, GO:0005524=PMID:14976552, GO:0005737=PMID:22713462, GO:0007067=GO_REF:0000037, GO:0018105=GO_REF:0000019, GO:0070059=PMID:22713462, GO:0016301=GO_REF:0000038, GO:0004674=PMID:14976552, GO:0000086=PMID:23029325, GO:0030182=GO_REF:0000024, GO:0006468=PMID:14976552, GO:0061178=GO_REF:0000024, GO:0051301=GO_REF:0000037} Q8IWQ3 Serine/threonine-protein kinase BRSK2 protein 20121011 {GO:0005813=IDA, GO:0048471=IEA, GO:0000287=IDA, GO:0031532=IMP, GO:0019901=IEA, GO:0005783=IEA, GO:0050321=IDA, GO:0030010=ISS, GO:0007409=ISS, GO:0006887=IEA, GO:0005524=IDA, GO:0005737=IDA, GO:0007067=IEA, GO:0018105=IEA, GO:0070059=IMP, GO:0016301=IEA, GO:0004674=IDA, GO:0000086=IMP, GO:0030182=ISS, GO:0006468=IDA, GO:0061178=ISS, GO:0051301=IEA} G2/M transition of mitotic cell cycle, actin cytoskeleton reorganization, axonogenesis, cell division, establishment of cell polarity, exocytosis, intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress, mitosis, neuron differentiation, peptidyl-serine phosphorylation, protein phosphorylation, regulation of insulin secretion involved in cellular response to glucose stimulus centrosome, cytoplasm, endoplasmic reticulum, perinuclear region of cytoplasm ATP binding, kinase activity, magnesium ion binding, protein kinase binding, protein serine/threonine kinase activity, tau-protein kinase activity Human BRWD1 HPA UniProtKB {GO:0003674=GO_REF:0000015, GO:0005737=GO_REF:0000052, GO:0006357=GO_REF:0000019, GO:0008360=PMID:21834987, GO:0007010=PMID:21834987, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0006351=GO_REF:0000037} Q9NSI6 Bromodomain and WD repeat-containing protein 1 protein 20110516 {GO:0003674=ND, GO:0005737=IDA, GO:0006357=IEA, GO:0008360=IMP, GO:0007010=IMP, GO:0005730=IDA, GO:0005634=IDA, GO:0006351=IEA} cytoskeleton organization, regulation of cell shape, regulation of transcription from RNA polymerase II promoter, transcription, DNA-dependent cytoplasm, nucleolus, nucleus molecular_function Human BRWD3 UniProtKB UniProtKB {GO:0008360=PMID:21834987, GO:0007010=PMID:21834987} Q6RI45 Bromodomain and WD repeat-containing protein 3 protein 20110926 {GO:0008360=IMP, GO:0007010=IMP} cytoskeleton organization, regulation of cell shape Human BSCL2 UniProtKB UniProtKB {GO:0016042=GO_REF:0000037, GO:0008150=GO_REF:0000015, GO:0003674=GO_REF:0000015, GO:0008219=GO_REF:0000037, GO:0050995=GO_REF:0000024, GO:0019915=PMID:19278620, GO:0045444=GO_REF:0000024, GO:0030176=PMID:14981520, GO:0034389=PMID:19278620} Q96G97 Seipin protein 20120618 {GO:0016042=IEA, GO:0008150=ND, GO:0003674=ND, GO:0008219=IEA, GO:0050995=ISS, GO:0019915=IMP, GO:0045444=ISS, GO:0030176=IDA, GO:0034389=IMP} biological_process, cell death, fat cell differentiation, lipid catabolic process, lipid particle organization, lipid storage, negative regulation of lipid catabolic process integral to endoplasmic reticulum membrane molecular_function Human BSDC1 null null {} null null null null {} null null null BSG Reactome UniProtKB {GO:0042470=GO_REF:0000039, GO:0005886=Reactome:REACT_16988, GO:0007566=GO_REF:0000019, GO:0043434=GO_REF:0000019, GO:0044281=Reactome:REACT_111217, GO:0050900=Reactome:REACT_12051, GO:0005537=GO_REF:0000037, GO:0051591=GO_REF:0000019, GO:0005739=GO_REF:0000019, GO:0042383=GO_REF:0000019, GO:0046697=GO_REF:0000019, GO:0000139=Reactome:REACT_12637, GO:0016020=GO_REF:0000002, GO:0007596=Reactome:REACT_604, GO:0006090=Reactome:REACT_2071, GO:0042475=GO_REF:0000019, GO:0045121=GO_REF:0000019, GO:0016021=GO_REF:0000037, GO:0002080=GO_REF:0000019, GO:0046689=GO_REF:0000019, GO:0007166=PMID:9767135} P35613 Basigin protein 20071128 {GO:0042470=IEA, GO:0005886=TAS, GO:0007566=IEA, GO:0043434=IEA, GO:0044281=TAS, GO:0050900=TAS, GO:0005537=IEA, GO:0051591=IEA, GO:0005739=IEA, GO:0042383=IEA, GO:0046697=IEA, GO:0000139=TAS, GO:0016020=IEA, GO:0007596=TAS, GO:0006090=TAS, GO:0042475=IEA, GO:0045121=IEA, GO:0016021=IEA, GO:0002080=IEA, GO:0046689=IEA, GO:0007166=TAS} blood coagulation, cell surface receptor signaling pathway, decidualization, embryo implantation, leukocyte migration, odontogenesis of dentin-containing tooth, pyruvate metabolic process, response to cAMP, response to mercury ion, response to peptide hormone stimulus, small molecule metabolic process Golgi membrane, acrosomal membrane, integral to membrane, melanosome, membrane, membrane raft, mitochondrion, plasma membrane, sarcolemma mannose binding Human BSN HPA UniProtKB {GO:0048786=GO_REF:0000019, GO:0044306=GO_REF:0000019, GO:0005737=GO_REF:0000052, GO:0030054=GO_REF:0000037, GO:0015630=GO_REF:0000052, GO:0005730=GO_REF:0000052, GO:0007268=PMID:10329005, GO:0005634=GO_REF:0000052, GO:0030425=GO_REF:0000024, GO:0046872=GO_REF:0000037} Q9UPA5 Protein bassoon protein 20110516 {GO:0048786=IEA, GO:0044306=IEA, GO:0005737=IDA, GO:0030054=IEA, GO:0015630=IDA, GO:0005730=IDA, GO:0007268=TAS, GO:0005634=IDA, GO:0030425=ISS, GO:0046872=IEA} synaptic transmission cell junction, cytoplasm, dendrite, microtubule cytoskeleton, neuron projection terminus, nucleolus, nucleus, presynaptic active zone metal ion binding Human BSND Reactome UniProtKB {GO:0016323=GO_REF:0000024, GO:0043234=GO_REF:0000024, GO:0005737=GO_REF:0000039, GO:0034220=Reactome:REACT_25300, GO:0005886=Reactome:REACT_160109, GO:0005887=GO_REF:0000024, GO:0055085=Reactome:REACT_15518, GO:0005254=GO_REF:0000024, GO:0017081=GO_REF:0000019} Q8WZ55 Barttin protein 20121214 {GO:0016323=ISS, GO:0043234=ISS, GO:0005737=IEA, GO:0034220=TAS, GO:0005886=TAS, GO:0005887=ISS, GO:0055085=TAS, GO:0005254=ISS, GO:0017081=IEA} ion transmembrane transport, transmembrane transport basolateral plasma membrane, cytoplasm, integral to plasma membrane, plasma membrane, protein complex chloride channel activity, chloride channel regulator activity Human BSPRY HPA UniProtKB {GO:0005737=GO_REF:0000052, GO:0048471=GO_REF:0000019, GO:0016020=GO_REF:0000039, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0006816=GO_REF:0000037, GO:0008270=GO_REF:0000002, GO:0005925=GO_REF:0000052, GO:0031252=GO_REF:0000019} Q5W0U4 B box and SPRY domain-containing protein protein 20111111 {GO:0005737=IDA, GO:0048471=IEA, GO:0016020=IEA, GO:0005730=IDA, GO:0005634=IDA, GO:0006816=IEA, GO:0008270=IEA, GO:0005925=IDA, GO:0031252=IEA} calcium ion transport cell leading edge, cytoplasm, focal adhesion, membrane, nucleolus, nucleus, perinuclear region of cytoplasm zinc ion binding Human BST1 PINC UniProtKB {GO:0003953=GO_REF:0000003, GO:0005886=GO_REF:0000039, GO:0006959=PMID:8202488, GO:0007275=PMID:8202488, GO:0031225=GO_REF:0000037, GO:0019898=PMID:8202488} Q10588 ADP-ribosyl cyclase 2 protein 20031119 {GO:0003953=IEA, GO:0005886=IEA, GO:0006959=TAS, GO:0007275=TAS, GO:0031225=IEA, GO:0019898=TAS} humoral immune response, multicellular organismal development anchored to membrane, extrinsic to membrane, plasma membrane NAD+ nucleosidase activity Human BST2 GOC UniProtKB {GO:0005515=PMID:19564354, GO:0030308=PMID:22065321, GO:0005886=PMID:19036818, GO:0008283=PMID:7607676, GO:0035456=GO_REF:0000024, GO:0035455=GO_REF:0000024, GO:0007267=PMID:7607676, GO:0031225=GO_REF:0000037, GO:0042803=PMID:20399176, GO:0051607=PMID:20399176, GO:0016324=GO_REF:0000024, GO:0005737=PMID:22065321, GO:0044459=PMID:20399176, GO:0006959=PMID:7607676, GO:0002737=PMID:19564354, GO:0032956=GO_REF:0000024, GO:0004871=PMID:12761501, GO:0034341=GO_REF:0000024, GO:0043123=PMID:12761501, GO:0045071=PMID:20943977, GO:0030336=PMID:22065321, GO:0005794=GO_REF:0000039, GO:0009986=GO_REF:0000024, GO:0005770=GO_REF:0000039, GO:0007275=PMID:7607676, GO:0009615=PMID:19036818, GO:1901253=PMID:20686043, GO:0007165=PMID:12761501, GO:0042113=GO_REF:0000037, GO:0005887=PMID:7607676, GO:0045087=PMID:19036818, GO:0008191=PMID:22065321, GO:0045121=GO_REF:0000039} Q10589 Bone marrow stromal antigen 2 protein 20130413 {GO:0005515=IPI, GO:0030308=IDA, GO:0005886=IDA, GO:0008283=TAS, GO:0035456=ISS, GO:0035455=ISS, GO:0007267=TAS, GO:0031225=IEA, GO:0042803=IPI, GO:0051607=IDA, GO:0016324=ISS, GO:0005737=IDA, GO:0044459=IDA, GO:0006959=TAS, GO:0002737=IDA, GO:0032956=ISS, GO:0004871=IMP, GO:0034341=ISS, GO:0043123=IMP, GO:0045071=IDA, GO:0030336=IDA, GO:0005794=IEA, GO:0009986=ISS, GO:0005770=IEA, GO:0007275=TAS, GO:0009615=IDA, GO:1901253=IDA, GO:0007165=IMP, GO:0042113=IEA, GO:0005887=TAS, GO:0045087=IDA, GO:0008191=IDA, GO:0045121=IEA} B cell activation, cell proliferation, cell-cell signaling, defense response to virus, humoral immune response, innate immune response, multicellular organismal development, negative regulation of cell growth, negative regulation of cell migration, negative regulation of egress of virus within host cell, negative regulation of plasmacytoid dendritic cell cytokine production, negative regulation of viral genome replication, positive regulation of I-kappaB kinase/NF-kappaB cascade, regulation of actin cytoskeleton organization, response to interferon-alpha, response to interferon-beta, response to interferon-gamma, response to virus, signal transduction Golgi apparatus, anchored to membrane, apical plasma membrane, cell surface, cytoplasm, integral to plasma membrane, late endosome, membrane raft, plasma membrane, plasma membrane part metalloendopeptidase inhibitor activity, protein binding, protein homodimerization activity, signal transducer activity Human BTAF1 UniProtKB UniProtKB {GO:0003700=PMID:9342322, GO:0004386=GO_REF:0000037, GO:0005634=GO_REF:0000029, GO:0045892=PMID:9488487, GO:0005524=GO_REF:0000037, GO:0003677=GO_REF:0000037} O14981 TATA-binding protein-associated factor 172 protein 20020606 {GO:0003700=NAS, GO:0004386=IEA, GO:0005634=NAS, GO:0045892=NAS, GO:0005524=IEA, GO:0003677=IEA} negative regulation of transcription, DNA-dependent nucleus ATP binding, DNA binding, helicase activity, sequence-specific DNA binding transcription factor activity Human BTBD1 LIFEdb UniProtKB {GO:0005515=PMID:12878161, GO:0043234=GO_REF:0000054, GO:0016567=GO_REF:0000041, GO:0000932=PMID:12878161, GO:0043393=PMID:11179693} Q9H0C5 BTB/POZ domain-containing protein 1 protein 20100607 {GO:0005515=IPI, GO:0043234=IDA, GO:0016567=IEA, GO:0000932=IDA, GO:0043393=NAS} protein ubiquitination, regulation of protein binding cytoplasmic mRNA processing body, protein complex protein binding Human BTBD10 HPA UniProtKB {GO:0005737=GO_REF:0000052, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052} Q9BSF8 BTB/POZ domain-containing protein 10 protein 20111111 {GO:0005737=IDA, GO:0005730=IDA, GO:0005634=IDA} cytoplasm, nucleolus, nucleus Human BTBD16 null null {} null null null null {} null null null BTBD2 IntAct UniProtKB {GO:0005515=PMID:19615732, GO:0000932=PMID:12878161} Q9BX70 BTB/POZ domain-containing protein 2 protein 20130415 {GO:0005515=IPI, GO:0000932=IDA} cytoplasmic mRNA processing body protein binding Human UniProtKB:Q7L5N1 BTBD3 null null {} null null null null {} null null null BTBD6 UniProtKB UniProtKB {GO:0000932=GO_REF:0000039} Q96KE9 BTB/POZ domain-containing protein 6 protein 20130413 {GO:0000932=IEA} cytoplasmic mRNA processing body Human UniProtKB-SubCell:SL-0230 BTBD7 null null {} null null null null {} null null null BTBD8 HPA UniProtKB {GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052} Q5XKL5 BTB/POZ domain-containing protein 8 protein 20101115 {GO:0005730=IDA, GO:0005634=IDA} nucleolus, nucleus NOT Human BTBD9 InterPro UniProtKB {GO:0007155=GO_REF:0000002} Q96Q07 BTB/POZ domain-containing protein 9 protein 20130413 {GO:0007155=IEA} cell adhesion Human InterPro:IPR000421 BTC Reactome UniProtKB {GO:0008284=GO_REF:0000019, GO:0043066=GO_REF:0000019, GO:0005154=PMID:8144591, GO:0048011=Reactome:REACT_11061, GO:0005886=GO_REF:0000039, GO:0048015=Reactome:REACT_12464, GO:0005576=Reactome:REACT_147854, GO:0005615=GO_REF:0000039, GO:0007173=Reactome:REACT_9417, GO:0008543=Reactome:REACT_9470, GO:0045087=Reactome:REACT_6802, GO:0051781=GO_REF:0000037, GO:0016021=GO_REF:0000037, GO:0008083=GO_REF:0000037} P35070 Probetacellulin protein 20130301 {GO:0008284=IEA, GO:0043066=IEA, GO:0005154=TAS, GO:0048011=TAS, GO:0005886=IEA, GO:0048015=TAS, GO:0005576=TAS, GO:0005615=IEA, GO:0007173=TAS, GO:0008543=TAS, GO:0045087=TAS, GO:0051781=IEA, GO:0016021=IEA, GO:0008083=IEA} epidermal growth factor receptor signaling pathway, fibroblast growth factor receptor signaling pathway, innate immune response, negative regulation of apoptotic process, neurotrophin TRK receptor signaling pathway, phosphatidylinositol-mediated signaling, positive regulation of cell division, positive regulation of cell proliferation extracellular region, extracellular space, integral to membrane, plasma membrane epidermal growth factor receptor binding, growth factor activity Human BTD PINC UniProtKB {GO:0047708=GO_REF:0000003, GO:0006807=GO_REF:0000002, GO:0008544=PMID:7550325, GO:0016811=GO_REF:0000002, GO:0005730=GO_REF:0000019, GO:0004075=PMID:7509806, GO:0045177=GO_REF:0000019, GO:0043204=GO_REF:0000019, GO:0007417=PMID:7550325, GO:0005615=GO_REF:0000039} P43251 Biotinidase protein 20030904 {GO:0047708=IEA, GO:0006807=IEA, GO:0008544=TAS, GO:0016811=IEA, GO:0005730=IEA, GO:0004075=TAS, GO:0045177=IEA, GO:0043204=IEA, GO:0007417=TAS, GO:0005615=IEA} central nervous system development, epidermis development, nitrogen compound metabolic process apical part of cell, extracellular space, nucleolus, perikaryon biotin carboxylase activity, biotinidase activity, hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides Human BTF3 PINC UniProtKB {GO:0006355=GO_REF:0000037, GO:0006366=PMID:2320128, GO:0005634=GO_REF:0000039, GO:0001701=GO_REF:0000019} P20290 Transcription factor BTF3 protein 20030904 {GO:0006355=IEA, GO:0006366=TAS, GO:0005634=IEA, GO:0001701=IEA} in utero embryonic development, regulation of transcription, DNA-dependent, transcription from RNA polymerase II promoter nucleus Human BTF3L4 null null {} null null null null {} null null null BTG1 IntAct UniProtKB {GO:0003712=PMID:11420681, GO:0005515=PMID:16189514, GO:0006355=PMID:11420681, GO:0030308=PMID:15033446, GO:0008285=PMID:11420681, GO:0005634=PMID:11420681, GO:0042981=PMID:9690562, GO:0045766=PMID:15033446, GO:0005737=PMID:11420681, GO:0016477=PMID:15033446, GO:0045663=PMID:11420681, GO:0019899=PMID:8663146, GO:0019900=PMID:9820826, GO:0045603=PMID:15033446} P62324 Protein BTG1 protein 20130415 {GO:0003712=NAS, GO:0005515=IPI, GO:0006355=NAS, GO:0030308=NAS, GO:0008285=IDA, GO:0005634=IDA, GO:0042981=IMP, GO:0045766=IMP, GO:0005737=IDA, GO:0016477=NAS, GO:0045663=IDA, GO:0019899=IPI, GO:0019900=NAS, GO:0045603=IMP} cell migration, negative regulation of cell growth, negative regulation of cell proliferation, positive regulation of angiogenesis, positive regulation of endothelial cell differentiation, positive regulation of myoblast differentiation, regulation of apoptotic process, regulation of transcription, DNA-dependent cytoplasm, nucleus enzyme binding, kinase binding, protein binding, transcription cofactor activity Human UniProtKB:Q9UFF9 BTG2 IntAct UniProtKB {GO:0005515=PMID:11136725, GO:0017148=PMID:23236473, GO:0008306=GO_REF:0000019, GO:0014070=GO_REF:0000019, GO:0021542=GO_REF:0000019, GO:0043066=GO_REF:0000019, GO:2000178=GO_REF:0000019, GO:0008285=PMID:23236473, GO:0021954=GO_REF:0000019, GO:0060213=PMID:18337750, GO:0043434=GO_REF:0000019, GO:0009952=GO_REF:0000019, GO:0006974=PMID:8944033, GO:0031175=PMID:18773938, GO:0009612=GO_REF:0000019, GO:0001077=GO_REF:0000019, GO:0006281=PMID:8944033, GO:0051602=GO_REF:0000019, GO:0006479=GO_REF:0000019} P78543 Protein BTG2 protein 20130415 {GO:0005515=IPI, GO:0017148=IDA, GO:0008306=IEA, GO:0014070=IEA, GO:0021542=IEA, GO:0043066=IEA, GO:2000178=IEA, GO:0008285=IMP, GO:0021954=IEA, GO:0060213=IDA, GO:0043434=IEA, GO:0009952=IEA, GO:0006974=IDA, GO:0031175=IMP, GO:0009612=IEA, GO:0001077=IEA, GO:0006281=TAS, GO:0051602=IEA, GO:0006479=IEA} DNA repair, anterior/posterior pattern specification, associative learning, central nervous system neuron development, dentate gyrus development, negative regulation of apoptotic process, negative regulation of cell proliferation, negative regulation of neural precursor cell proliferation, negative regulation of translation, neuron projection development, positive regulation of nuclear-transcribed mRNA poly(A) tail shortening, protein methylation, response to DNA damage stimulus, response to electrical stimulus, response to mechanical stimulus, response to organic cyclic compound, response to peptide hormone stimulus RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription, protein binding Human UniProtKB:Q9UIV1 BTG3 PINC UniProtKB {GO:0005737=PMID:9632145, GO:0008285=PMID:9632145, GO:0045930=PMID:9632145} Q14201 Protein BTG3 protein 20030904 {GO:0005737=IDA, GO:0008285=TAS, GO:0045930=IDA} negative regulation of cell proliferation, negative regulation of mitotic cell cycle cytoplasm Human BTG4 UniProtKB UniProtKB {GO:0008285=PMID:10995567, GO:0045930=GO_REF:0000019, GO:0030182=PMID:10995567, GO:0007050=PMID:10995567, GO:0005575=GO_REF:0000015} Q9NY30 Protein BTG4 protein 20011002 {GO:0008285=TAS, GO:0045930=IEA, GO:0030182=TAS, GO:0007050=TAS, GO:0005575=ND} cell cycle arrest, negative regulation of cell proliferation, negative regulation of mitotic cell cycle, neuron differentiation cellular_component Human BTK HPA UniProtKB {GO:0005515=PMID:22939624, GO:0050853=PMID:19290921, GO:0034142=Reactome:REACT_6894, GO:0019722=PMID:15046600, GO:0005886=Reactome:REACT_118781, GO:0045579=PMID:19290921, GO:0007249=GO_REF:0000019, GO:0005634=PMID:19290921, GO:0046872=GO_REF:0000037, GO:0043231=GO_REF:0000052, GO:0042802=PMID:11577348, GO:0005829=Reactome:REACT_150418, GO:0035556=GO_REF:0000002, GO:0005737=PMID:15046600, GO:0005543=GO_REF:0000002, GO:0051092=PMID:19290921, GO:0002755=Reactome:REACT_6788, GO:0002902=PMID:19290921, GO:0048469=GO_REF:0000019, GO:0038124=Reactome:REACT_8006, GO:0038123=Reactome:REACT_8005, GO:0034134=Reactome:REACT_7980, GO:0005547=PMID:17823121, GO:0018108=GO_REF:0000019, GO:0031410=GO_REF:0000019, GO:0002224=Reactome:REACT_6966, GO:0097190=PMID:8688094, GO:0005524=GO_REF:0000038, GO:0006351=GO_REF:0000037, GO:0002721=PMID:19290921, GO:0002250=PMID:19290921, GO:0042113=PMID:19290921, GO:0045087=Reactome:REACT_6802, GO:0007498=PMID:8013627, GO:0006468=PMID:11913944, GO:0045121=PMID:15046600, GO:0004713=GO_REF:0000038, GO:0004715=PMID:19290921} Q5JY90 Tyrosine-protein kinase BTK protein 20101115 {GO:0005515=IPI, GO:0050853=TAS, GO:0034142=TAS, GO:0019722=TAS, GO:0005886=TAS, GO:0045579=TAS, GO:0007249=IEA, GO:0005634=TAS, GO:0046872=IEA, GO:0043231=IDA, GO:0042802=IPI, GO:0005829=TAS, GO:0035556=IEA, GO:0005737=TAS, GO:0005543=IEA, GO:0051092=TAS, GO:0002755=TAS, GO:0002902=TAS, GO:0048469=IEA, GO:0038124=TAS, GO:0038123=TAS, GO:0034134=TAS, GO:0005547=IDA, GO:0018108=IEA, GO:0031410=IEA, GO:0002224=TAS, GO:0097190=TAS, GO:0005524=IEA, GO:0006351=IEA, GO:0002721=TAS, GO:0002250=TAS, GO:0042113=TAS, GO:0045087=TAS, GO:0007498=TAS, GO:0006468=TAS, GO:0045121=IDA, GO:0004713=IEA, GO:0004715=TAS} B cell activation, B cell receptor signaling pathway, I-kappaB kinase/NF-kappaB cascade, MyD88-dependent toll-like receptor signaling pathway, adaptive immune response, apoptotic signaling pathway, calcium-mediated signaling, cell maturation, innate immune response, intracellular signal transduction, mesoderm development, peptidyl-tyrosine phosphorylation, positive regulation of B cell differentiation, positive regulation of NF-kappaB transcription factor activity, protein phosphorylation, regulation of B cell apoptotic process, regulation of B cell cytokine production, toll-like receptor 2 signaling pathway, toll-like receptor 4 signaling pathway, toll-like receptor TLR1:TLR2 signaling pathway, toll-like receptor TLR6:TLR2 signaling pathway, toll-like receptor signaling pathway, transcription, DNA-dependent cytoplasm, cytoplasmic vesicle, cytosol, intracellular membrane-bounded organelle, membrane raft, nucleus, plasma membrane ATP binding, identical protein binding, metal ion binding, non-membrane spanning protein tyrosine kinase activity, phosphatidylinositol-3,4,5-trisphosphate binding, phospholipid binding, protein binding, protein tyrosine kinase activity Human BTLA Reactome UniProtKB {GO:0002768=GO_REF:0000019, GO:0005886=Reactome:REACT_19406, GO:0046642=GO_REF:0000019, GO:0005887=GO_REF:0000019, GO:0031295=Reactome:REACT_19344, GO:0030889=GO_REF:0000019, GO:0004872=GO_REF:0000019, GO:0009897=GO_REF:0000019} Q7Z6A9 B- and T-lymphocyte attenuator protein 20070515 {GO:0002768=IEA, GO:0005886=TAS, GO:0046642=IEA, GO:0005887=IEA, GO:0031295=TAS, GO:0030889=IEA, GO:0004872=IEA, GO:0009897=IEA} T cell costimulation, immune response-regulating cell surface receptor signaling pathway, negative regulation of B cell proliferation, negative regulation of alpha-beta T cell proliferation external side of plasma membrane, integral to plasma membrane, plasma membrane receptor activity Human BTN1A1 PINC UniProtKB {GO:0005887=PMID:8611614, GO:0004872=PMID:8611614, GO:0005576=GO_REF:0000039} Q13410 Butyrophilin subfamily 1 member A1 protein 20030904 {GO:0005887=TAS, GO:0004872=TAS, GO:0005576=IEA} extracellular region, integral to plasma membrane receptor activity Human BTN2A1 PINC UniProtKB {GO:0006629=PMID:9382921, GO:0003674=GO_REF:0000015, GO:0005887=PMID:9382921} Q7KYR7 Butyrophilin subfamily 2 member A1 protein 20050308 {GO:0006629=TAS, GO:0003674=ND, GO:0005887=TAS} lipid metabolic process integral to plasma membrane molecular_function Human BTN2A2 UniProtKB UniProtKB {GO:0031324=GO_REF:0000024, GO:0046007=GO_REF:0000024, GO:0016021=GO_REF:0000037, GO:0050710=GO_REF:0000024} Q8WVV5 Butyrophilin subfamily 2 member A2 protein 20110401 {GO:0031324=ISS, GO:0046007=ISS, GO:0016021=IEA, GO:0050710=ISS} negative regulation of activated T cell proliferation, negative regulation of cellular metabolic process, negative regulation of cytokine secretion integral to membrane Human UniProtKB:A4QPC6 BTN3A1 IntAct UniProtKB {GO:0005515=PMID:21982860, GO:0072643=PMID:21918970, GO:0050852=PMID:21918970, GO:0050663=PMID:21918970, GO:0005886=PMID:21918970, GO:0050798=PMID:21918970, GO:0016021=GO_REF:0000037} O00481 Butyrophilin subfamily 3 member A1 protein 20130415 {GO:0005515=IPI, GO:0072643=IMP, GO:0050852=IDA, GO:0050663=IDA, GO:0005886=IDA, GO:0050798=IMP, GO:0016021=IEA} T cell receptor signaling pathway, activated T cell proliferation, cytokine secretion, interferon-gamma secretion integral to membrane, plasma membrane protein binding Human UniProtKB:P04155 BTN3A2 UniProtKB UniProtKB {GO:0072643=PMID:21918970, GO:0005886=PMID:22767497, GO:0016021=GO_REF:0000037, GO:0002456=PMID:22767497} P78410 Butyrophilin subfamily 3 member A2 protein 20121030 {GO:0072643=IMP, GO:0005886=IDA, GO:0016021=IEA, GO:0002456=IMP} T cell mediated immunity, interferon-gamma secretion integral to membrane, plasma membrane Human BTN3A3 UniProtKB UniProtKB {GO:0005886=PMID:22767497, GO:0016021=GO_REF:0000037, GO:0002456=PMID:22767497} O00478 Butyrophilin subfamily 3 member A3 protein 20121030 {GO:0005886=IDA, GO:0016021=IEA, GO:0002456=IMP} T cell mediated immunity integral to membrane, plasma membrane Human BTNL2 UniProtKB UniProtKB {GO:0016021=GO_REF:0000037} Q9UIR0 Butyrophilin-like protein 2 protein 20130413 {GO:0016021=IEA} integral to membrane Human UniProtKB-KW:KW-0812 BTRC BHF-UCL UniProtKB {GO:0005515=PMID:20708156, GO:0006511=PMID:15448698, GO:0004842=PMID:15448698, GO:0016567=PMID:16885022, GO:0008013=GO_REF:0000019, GO:0045309=GO_REF:0000019, GO:0045879=PMID:11001584, GO:0005634=GO_REF:0000039, GO:0031145=Reactome:REACT_6828, GO:0005829=Reactome:REACT_118856, GO:0031648=PMID:16885022, GO:0030163=GO_REF:0000019, GO:0006470=GO_REF:0000019, GO:0046983=GO_REF:0000002, GO:0051726=GO_REF:0000019, GO:0016032=Reactome:REACT_6185, GO:0016055=GO_REF:0000037, GO:0043122=GO_REF:0000019, GO:0000209=GO_REF:0000019, GO:0051437=Reactome:REACT_6821, GO:0051439=Reactome:REACT_6837, GO:0045862=PMID:16885022, GO:0007165=PMID:9990853, GO:0033598=GO_REF:0000019, GO:0071407=GO_REF:0000019, GO:0061136=GO_REF:0000019, GO:0019048=GO_REF:0000037, GO:0042753=GO_REF:0000019, GO:0000278=Reactome:REACT_152, GO:0045893=GO_REF:0000019, GO:0045892=PMID:19966869, GO:0060444=GO_REF:0000019, GO:0019005=PMID:19966869} Q9Y297 F-box/WD repeat-containing protein 1A protein 20111117 {GO:0005515=IPI, GO:0006511=IDA, GO:0004842=IDA, GO:0016567=IDA, GO:0008013=IEA, GO:0045309=IEA, GO:0045879=TAS, GO:0005634=IEA, GO:0031145=TAS, GO:0005829=TAS, GO:0031648=IMP, GO:0030163=IEA, GO:0006470=IEA, GO:0046983=IEA, GO:0051726=IEA, GO:0016032=TAS, GO:0016055=IEA, GO:0043122=IEA, GO:0000209=IEA, GO:0051437=TAS, GO:0051439=TAS, GO:0045862=IMP, GO:0007165=TAS, GO:0033598=IEA, GO:0071407=IEA, GO:0061136=IEA, GO:0019048=IEA, GO:0042753=IEA, GO:0000278=TAS, GO:0045893=IEA, GO:0045892=IMP, GO:0060444=IEA, GO:0019005=IDA} Wnt receptor signaling pathway, anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process, branching involved in mammary gland duct morphogenesis, cellular response to organic cyclic compound, mammary gland epithelial cell proliferation, mitotic cell cycle, negative regulation of smoothened signaling pathway, negative regulation of transcription, DNA-dependent, positive regulation of circadian rhythm, positive regulation of proteolysis, positive regulation of transcription, DNA-dependent, positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle, protein catabolic process, protein dephosphorylation, protein destabilization, protein polyubiquitination, protein ubiquitination, regulation of I-kappaB kinase/NF-kappaB cascade, regulation of cell cycle, regulation of proteasomal protein catabolic process, regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle, signal transduction, ubiquitin-dependent protein catabolic process, viral reproduction, virus-host interaction SCF ubiquitin ligase complex, cytosol, nucleus beta-catenin binding, protein binding, protein dimerization activity, protein phosphorylated amino acid binding, ubiquitin-protein ligase activity Human BUB1 Reactome UniProtKB {GO:0005515=PMID:17981135, GO:0000236=Reactome:REACT_682, GO:0007094=PMID:9790499, GO:0000780=GO_REF:0000019, GO:0007093=PMID:9521327, GO:0008283=GO_REF:0000019, GO:0051983=PMID:19487456, GO:0006915=GO_REF:0000037, GO:0005524=GO_REF:0000037, GO:0005829=Reactome:REACT_150414, GO:0004672=PMID:10198256, GO:0007059=GO_REF:0000037, GO:0004674=GO_REF:0000037, GO:0019048=GO_REF:0000037, GO:0000087=Reactome:REACT_910, GO:0071173=PMID:15525512, GO:0000777=PMID:19465021, GO:0000776=PMID:22331848, GO:0000278=Reactome:REACT_152, GO:0000090=Reactome:REACT_1275, GO:0007063=PMID:15723797, GO:0016772=GO_REF:0000002, GO:0051301=GO_REF:0000037} O43683 Mitotic checkpoint serine/threonine-protein kinase BUB1 protein 20120924 {GO:0005515=IPI, GO:0000236=TAS, GO:0007094=TAS, GO:0000780=IEA, GO:0007093=TAS, GO:0008283=IEA, GO:0051983=IMP, GO:0006915=IEA, GO:0005524=IEA, GO:0005829=TAS, GO:0004672=TAS, GO:0007059=IEA, GO:0004674=IEA, GO:0019048=IEA, GO:0000087=TAS, GO:0071173=IDA, GO:0000777=IDA, GO:0000776=IDA, GO:0000278=TAS, GO:0000090=TAS, GO:0007063=IDA, GO:0016772=IEA, GO:0051301=IEA} M phase of mitotic cell cycle, apoptotic process, cell division, cell proliferation, chromosome segregation, mitotic anaphase, mitotic cell cycle, mitotic cell cycle checkpoint, mitotic prometaphase, mitotic spindle assembly checkpoint, regulation of chromosome segregation, regulation of sister chromatid cohesion, spindle assembly checkpoint, virus-host interaction condensed chromosome kinetochore, condensed nuclear chromosome, centromeric region, cytosol, kinetochore ATP binding, protein binding, protein kinase activity, protein serine/threonine kinase activity, transferase activity, transferring phosphorus-containing groups Human BUB1B BHF-UCL UniProtKB {GO:0005515=PMID:20360068, GO:0007094=Reactome:REACT_2137, GO:0000236=Reactome:REACT_682, GO:0048471=PMID:20531406, GO:0007093=PMID:10477750, GO:0008283=PMID:10477750, GO:0034501=PMID:9660858, GO:0051233=PMID:9763420, GO:0031145=Reactome:REACT_6850, GO:0005829=Reactome:REACT_150414, GO:0005737=GO_REF:0000054, GO:0005680=PMID:10477750, GO:0000087=Reactome:REACT_910, GO:0007051=PMID:15504738, GO:0007091=GO_REF:0000019, GO:0005815=GO_REF:0000039, GO:0048015=PMID:15504738, GO:0006915=GO_REF:0000037, GO:0051436=Reactome:REACT_1041, GO:0071459=GO_REF:0000019, GO:0005524=GO_REF:0000037, GO:0051439=Reactome:REACT_6837, GO:0007049=PMID:15504738, GO:0007067=PMID:9763420, GO:0000940=PMID:19468067, GO:0004672=PMID:9763420, GO:0004674=GO_REF:0000037, GO:0000777=PMID:19465021, GO:0000776=PMID:22331848, GO:0000075=Reactome:REACT_1538, GO:0000778=GO_REF:0000019, GO:0000278=Reactome:REACT_152, GO:0000090=Reactome:REACT_1275, GO:0051301=GO_REF:0000037} O60566 Mitotic checkpoint serine/threonine-protein kinase BUB1 beta protein 20101105 {GO:0005515=IPI, GO:0007094=TAS, GO:0000236=TAS, GO:0048471=IDA, GO:0007093=TAS, GO:0008283=TAS, GO:0034501=IPI, GO:0051233=NAS, GO:0031145=TAS, GO:0005829=TAS, GO:0005737=IDA, GO:0005680=TAS, GO:0000087=TAS, GO:0007051=NAS, GO:0007091=IEA, GO:0005815=IEA, GO:0048015=NAS, GO:0006915=IEA, GO:0051436=TAS, GO:0071459=IEA, GO:0005524=IEA, GO:0051439=TAS, GO:0007049=NAS, GO:0007067=NAS, GO:0000940=IDA, GO:0004672=NAS, GO:0004674=IEA, GO:0000777=IDA, GO:0000776=IDA, GO:0000075=TAS, GO:0000778=IEA, GO:0000278=TAS, GO:0000090=TAS, GO:0051301=IEA} M phase of mitotic cell cycle, anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process, apoptotic process, cell cycle, cell cycle checkpoint, cell division, cell proliferation, metaphase/anaphase transition of mitotic cell cycle, mitosis, mitotic anaphase, mitotic cell cycle, mitotic cell cycle checkpoint, mitotic prometaphase, mitotic spindle assembly checkpoint, negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle, phosphatidylinositol-mediated signaling, protein localization to chromosome, centromeric region, protein localization to kinetochore, regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle, spindle organization anaphase-promoting complex, condensed chromosome kinetochore, condensed chromosome outer kinetochore, condensed nuclear chromosome kinetochore, cytoplasm, cytosol, kinetochore, microtubule organizing center, perinuclear region of cytoplasm, spindle midzone ATP binding, protein binding, protein kinase activity, protein serine/threonine kinase activity Human BUB3 HPA UniProtKB {GO:0005515=PMID:17289665, GO:0007094=Reactome:REACT_2137, GO:0000236=Reactome:REACT_682, GO:0051983=GO_REF:0000019, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0051436=Reactome:REACT_1041, GO:0031145=Reactome:REACT_6850, GO:0051439=Reactome:REACT_6837, GO:0005829=Reactome:REACT_150414, GO:0000070=GO_REF:0000019, GO:0007126=GO_REF:0000037, GO:0000087=Reactome:REACT_910, GO:0071173=PMID:15525512, GO:0000777=GO_REF:0000039, GO:0000776=PMID:9660858, GO:0000075=Reactome:REACT_1538, GO:0000278=Reactome:REACT_152, GO:0008608=PMID:18199686, GO:0000090=Reactome:REACT_1275, GO:0051301=GO_REF:0000037} O43684 Mitotic checkpoint protein BUB3 protein 20080205 {GO:0005515=IPI, GO:0007094=TAS, GO:0000236=TAS, GO:0051983=IEA, GO:0005730=IDA, GO:0005634=IDA, GO:0051436=TAS, GO:0031145=TAS, GO:0051439=TAS, GO:0005829=TAS, GO:0000070=IEA, GO:0007126=IEA, GO:0000087=TAS, GO:0071173=IDA, GO:0000777=IEA, GO:0000776=IDA, GO:0000075=TAS, GO:0000278=TAS, GO:0008608=IDA, GO:0000090=TAS, GO:0051301=IEA} M phase of mitotic cell cycle, anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process, attachment of spindle microtubules to kinetochore, cell cycle checkpoint, cell division, meiosis, mitotic anaphase, mitotic cell cycle, mitotic prometaphase, mitotic sister chromatid segregation, mitotic spindle assembly checkpoint, negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle, regulation of chromosome segregation, regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle, spindle assembly checkpoint condensed chromosome kinetochore, cytosol, kinetochore, nucleolus, nucleus protein binding NOT Human BUD13 BHF-UCL UniProtKB {GO:0006406=PMID:15565172, GO:0000398=PMID:15565172, GO:0070274=PMID:15565172} Q9BRD0 BUD13 homolog protein 20111208 {GO:0006406=ISS, GO:0000398=ISS, GO:0070274=ISS} mRNA export from nucleus, mRNA splicing, via spliceosome RES complex Human UniProtKB:P46947 BUD31 PINC UniProtKB {GO:0003700=PMID:7841202, GO:0006357=PMID:7841202, GO:0005634=GO_REF:0000039} P41223 Protein BUD31 homolog protein 20030904 {GO:0003700=TAS, GO:0006357=TAS, GO:0005634=IEA} regulation of transcription from RNA polymerase II promoter nucleus sequence-specific DNA binding transcription factor activity Human BYSL HPA UniProtKB {GO:0005515=PMID:9560222, GO:0007565=PMID:9560222, GO:0005737=GO_REF:0000039, GO:0042254=GO_REF:0000037, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0007155=PMID:9560222, GO:0043231=GO_REF:0000052} Q13895 Bystin protein 20101115 {GO:0005515=IPI, GO:0007565=TAS, GO:0005737=IEA, GO:0042254=IEA, GO:0005730=IDA, GO:0005634=IDA, GO:0007155=TAS, GO:0043231=IDA} cell adhesion, female pregnancy, ribosome biogenesis cytoplasm, intracellular membrane-bounded organelle, nucleolus, nucleus protein binding Human BZRAP1 IntAct UniProtKB {GO:0005515=PMID:21078624, GO:0005739=PMID:9915832, GO:0008150=GO_REF:0000015, GO:0005737=PMID:9915832, GO:0030156=PMID:9915832} O95153 Peripheral-type benzodiazepine receptor-associated protein 1 protein 20130415 {GO:0005515=IPI, GO:0005739=IDA, GO:0008150=ND, GO:0005737=IDA, GO:0030156=IPI} biological_process cytoplasm, mitochondrion benzodiazepine receptor binding, protein binding Human UniProtKB:O00555 BZW1 UniProtKB UniProtKB {GO:0005737=PMID:10942595, GO:0006355=GO_REF:0000037, GO:0016070=GO_REF:0000002, GO:0006351=GO_REF:0000037} Q7L1Q6 Basic leucine zipper and W2 domain-containing protein 1 protein 20060117 {GO:0005737=IDA, GO:0006355=IEA, GO:0016070=IEA, GO:0006351=IEA} RNA metabolic process, regulation of transcription, DNA-dependent, transcription, DNA-dependent cytoplasm Human BZW2 UniProtKB UniProtKB {GO:0016070=GO_REF:0000002, GO:0030154=GO_REF:0000037, GO:0007399=GO_REF:0000037} Q9Y6E2 Basic leucine zipper and W2 domain-containing protein 2 protein 20130413 {GO:0016070=IEA, GO:0030154=IEA, GO:0007399=IEA} RNA metabolic process, cell differentiation, nervous system development Human UniProtKB-KW:KW-0221 C10orf10 null null {} null null null null {} null null null C10orf114 null null {} null null null null {} null null null C10orf118 null null {} null null null null {} null null null C10orf12 null null {} null null null null {} null null null C10orf137 null null {} null null null null {} null null null C10orf2 null null {} null null null null {} null null null C10orf32 null null {} null null null null {} null null null C10orf35 UniProtKB UniProtKB {GO:0016021=GO_REF:0000037} Q96D05 Uncharacterized protein C10orf35 protein 20130413 {GO:0016021=IEA} integral to membrane Human UniProtKB-KW:KW-0812 C10orf54 UniProtKB UniProtKB {GO:0016021=GO_REF:0000037} Q9H7M9 Platelet receptor Gi24 protein 20130413 {GO:0016021=IEA} integral to membrane Human UniProtKB-KW:KW-0812 C10orf55 null null {} null null null null {} null null null C10orf62 IntAct UniProtKB {GO:0005515=PMID:19447967} Q5T681 Uncharacterized protein C10orf62 protein 20130415 {GO:0005515=IPI} protein binding Human UniProtKB:Q99750 C10orf76 UniProtKB UniProtKB {GO:0016021=GO_REF:0000037} Q5T2E6 UPF0668 protein C10orf76 protein 20130413 {GO:0016021=IEA} integral to membrane Human UniProtKB-KW:KW-0812 C10orf82 null null {} null null null null {} null null null C10orf88 ENSEMBL UniProtKB {GO:0042802=GO_REF:0000019} Q9H8K7 Uncharacterized protein C10orf88 protein 20130413 {GO:0042802=IEA} identical protein binding Human Ensembl:ENSMUSP00000050128 C10orf90 UniProtKB UniProtKB {GO:0007095=GO_REF:0000019, GO:0005813=PMID:20844083, GO:0005737=PMID:20844083, GO:0030308=GO_REF:0000019, GO:0042826=GO_REF:0000019, GO:0010212=GO_REF:0000019, GO:0050821=GO_REF:0000019, GO:0015629=PMID:20844083, GO:0009411=GO_REF:0000019} Q96M02 Centrosomal protein C10orf90 protein 20110817 {GO:0007095=IEA, GO:0005813=IDA, GO:0005737=IDA, GO:0030308=IEA, GO:0042826=IEA, GO:0010212=IEA, GO:0050821=IEA, GO:0015629=IDA, GO:0009411=IEA} mitotic G2 DNA damage checkpoint, negative regulation of cell growth, protein stabilization, response to UV, response to ionizing radiation actin cytoskeleton, centrosome, cytoplasm histone deacetylase binding Human C11orf1 HPA UniProtKB {GO:0003674=GO_REF:0000015, GO:0008150=GO_REF:0000015, GO:0005634=GO_REF:0000052} Q9H5F2 UPF0686 protein C11orf1 protein 20110516 {GO:0003674=ND, GO:0008150=ND, GO:0005634=IDA} biological_process nucleus molecular_function Human C11orf16 null null {} null null null null {} null null null C11orf30 null null {} null null null null {} null null null C11orf45 UniProtKB UniProtKB {GO:0005576=GO_REF:0000039} Q8TAV5 Putative uncharacterized protein C11orf45 protein 20130413 {GO:0005576=IEA} extracellular region Human UniProtKB-SubCell:SL-0243 C11orf48 null null {} null null null null {} null null null C11orf49 HPA UniProtKB {GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052} Q9H6J7 UPF0705 protein C11orf49 protein 20111111 {GO:0005730=IDA, GO:0005634=IDA} nucleolus, nucleus NOT Human C11orf52 null null {} null null null null {} null null null C11orf53 null null {} null null null null {} null null null C11orf54 IntAct UniProtKB {GO:0005515=PMID:19060904, GO:0016788=PMID:16522806, GO:0008270=PMID:16522806, GO:0005634=GO_REF:0000054} Q9H0W9 Ester hydrolase C11orf54 protein 20130415 {GO:0005515=IPI, GO:0016788=IDA, GO:0008270=IDA, GO:0005634=IDA} nucleus hydrolase activity, acting on ester bonds, protein binding, zinc ion binding Human UniProtKB:Q15645 C11orf57 null null {} null null null null {} null null null C11orf58 null null {} null null null null {} null null null C11orf63 null null {} null null null null {} null null null C11orf65 null null {} null null null null {} null null null C11orf68 null null {} null null null null {} null null null C11orf70 null null {} null null null null {} null null null C11orf71 null null {} null null null null {} null null null C11orf73 UniProtKB UniProtKB {GO:0005622=PMID:22541429, GO:0034605=PMID:22541429, GO:0030324=GO_REF:0000019, GO:0008565=PMID:22541429, GO:0007030=GO_REF:0000019, GO:0030544=PMID:22541429, GO:0005634=PMID:22541429, GO:0015031=PMID:22541429, GO:0006606=PMID:22541429, GO:0005829=PMID:22541429} Q53FT3 Protein Hikeshi protein 20120503 {GO:0005622=IDA, GO:0034605=IDA, GO:0030324=IEA, GO:0008565=IDA, GO:0007030=IEA, GO:0030544=IDA, GO:0005634=IDA, GO:0015031=IDA, GO:0006606=IDA, GO:0005829=IDA} Golgi organization, cellular response to heat, lung development, protein import into nucleus, protein transport cytosol, intracellular, nucleus Hsp70 protein binding, protein transporter activity Human C11orf74 null null {} null null null null {} null null null C11orf80 null null {} null null null null {} null null null C11orf82 ENSEMBL UniProtKB {GO:0071850=GO_REF:0000019, GO:0030097=GO_REF:0000019, GO:0005737=GO_REF:0000019, GO:2000270=GO_REF:0000019, GO:0007286=GO_REF:0000019, GO:0033554=GO_REF:0000019, GO:0005634=GO_REF:0000019} E9PQP9 Protein C11orf82 protein 20130413 {GO:0071850=IEA, GO:0030097=IEA, GO:0005737=IEA, GO:2000270=IEA, GO:0007286=IEA, GO:0033554=IEA, GO:0005634=IEA} cellular response to stress, hemopoiesis, mitotic cell cycle arrest, negative regulation of fibroblast apoptotic process, spermatid development cytoplasm, nucleus Human Ensembl:ENSMUSP00000032877 C11orf83 UniProtKB UniProtKB {GO:0005576=GO_REF:0000039} Q6UW78 UPF0723 protein C11orf83 protein 20130413 {GO:0005576=IEA} extracellular region Human UniProtKB-SubCell:SL-0243 C11orf84 null null {} null null null null {} null null null C12orf10 UniProtKB UniProtKB {GO:0005739=GO_REF:0000039, GO:0003674=GO_REF:0000015, GO:0043473=PMID:16996721, GO:0005634=GO_REF:0000039, GO:0005575=GO_REF:0000015} Q9HB07 UPF0160 protein MYG1, mitochondrial protein 20080604 {GO:0005739=IEA, GO:0003674=ND, GO:0043473=NAS, GO:0005634=IEA, GO:0005575=ND} pigmentation cellular_component, mitochondrion, nucleus molecular_function Human C12orf23 UniProtKB UniProtKB {GO:0016021=GO_REF:0000037} Q8WUH6 UPF0444 transmembrane protein C12orf23 protein 20130413 {GO:0016021=IEA} integral to membrane Human UniProtKB-KW:KW-0812 C12orf29 null null {} null null null null {} null null null C12orf39 HPA UniProtKB {GO:0030133=GO_REF:0000039, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0005576=GO_REF:0000039, GO:0043231=GO_REF:0000052} Q9BT56 Spexin protein 20081203 {GO:0030133=IEA, GO:0005730=IDA, GO:0005634=IDA, GO:0005576=IEA, GO:0043231=IDA} extracellular region, intracellular membrane-bounded organelle, nucleolus, nucleus, transport vesicle Human C12orf4 null null {} null null null null {} null null null C12orf43 null null {} null null null null {} null null null C12orf44 null null {} null null null null {} null null null C12orf45 null null {} null null null null {} null null null C12orf49 UniProtKB UniProtKB {GO:0005576=GO_REF:0000039} Q9H741 UPF0454 protein C12orf49 protein 20130413 {GO:0005576=IEA} extracellular region Human UniProtKB-SubCell:SL-0243 C12orf5 null null {} null null null null {} null null null C12orf52 null null {} null null null null {} null null null C12orf57 null null {} null null null null {} null null null C12orf63 null null {} null null null null {} null null null C12orf65 UniProtKB UniProtKB {GO:0005739=PMID:20186120, GO:0003747=GO_REF:0000002} Q9H3J6 Probable peptide chain release factor C12orf65, mitochondrial protein 20100305 {GO:0005739=NAS, GO:0003747=IEA} mitochondrion translation release factor activity Human C12orf68 LIFEdb UniProtKB {GO:0005737=GO_REF:0000054} Q52MB2 Uncharacterized protein C12orf68 protein 20100607 {GO:0005737=IDA} cytoplasm Human C12orf75 null null {} null null null null {} null null null C14orf1 LIFEdb UniProtKB {GO:0030133=GO_REF:0000054, GO:0003674=GO_REF:0000015, GO:0008150=GO_REF:0000015, GO:0005789=GO_REF:0000039, GO:0016126=GO_REF:0000037, GO:0016021=PMID:10449901} Q9UKR5 Probable ergosterol biosynthetic protein 28 protein 20100607 {GO:0030133=IDA, GO:0003674=ND, GO:0008150=ND, GO:0005789=IEA, GO:0016126=IEA, GO:0016021=NAS} biological_process, sterol biosynthetic process endoplasmic reticulum membrane, integral to membrane, transport vesicle molecular_function Human C14orf119 UniProtKB UniProtKB {GO:0005739=GO_REF:0000039} Q9NWQ9 Uncharacterized protein C14orf119 protein 20130413 {GO:0005739=IEA} mitochondrion Human UniProtKB-SubCell:SL-0173 C14orf142 null null {} null null null null {} null null null C14orf159 BHF-UCL UniProtKB {GO:0005739=GO_REF:0000039, GO:0008150=GO_REF:0000015, GO:0003674=GO_REF:0000015, GO:0005575=GO_REF:0000015} Q7Z3D6 UPF0317 protein C14orf159, mitochondrial protein 20120710 {GO:0005739=IEA, GO:0008150=ND, GO:0003674=ND, GO:0005575=ND} biological_process cellular_component, mitochondrion molecular_function Human C14orf166 HPA UniProtKB {GO:0005515=PMID:11507205, GO:0048471=GO_REF:0000039, GO:0005815=GO_REF:0000039, GO:0045944=PMID:16950395, GO:0019048=GO_REF:0000037, GO:0000993=PMID:16950395, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0072669=PMID:21311021, GO:0006351=GO_REF:0000037, GO:0042802=PMID:15147888} Q9Y224 UPF0568 protein C14orf166 protein 20111111 {GO:0005515=IPI, GO:0048471=IEA, GO:0005815=IEA, GO:0045944=IMP, GO:0019048=IEA, GO:0000993=IDA, GO:0005730=IDA, GO:0005634=IDA, GO:0072669=IDA, GO:0006351=IEA, GO:0042802=IPI} positive regulation of transcription from RNA polymerase II promoter, transcription, DNA-dependent, virus-host interaction microtubule organizing center, nucleolus, nucleus, perinuclear region of cytoplasm, tRNA-splicing ligase complex RNA polymerase II core binding, identical protein binding, protein binding NOT Human C14orf169 null null {} null null null null {} null null null C14orf2 InterPro UniProtKB {GO:0005739=GO_REF:0000002} G3V5Q3 Chromosome 14 open reading frame 2, isoform CRA_a protein 20130413 {GO:0005739=IEA} mitochondrion Human InterPro:IPR012574 C14orf80 null null {} null null null null {} null null null C14orf93 UniProtKB UniProtKB {GO:0005576=GO_REF:0000039} Q9H972 Uncharacterized protein C14orf93 protein 20130413 {GO:0005576=IEA} extracellular region Human UniProtKB-SubCell:SL-0243 C15orf38 null null {} null null null null {} null null null C15orf39 null null {} null null null null {} null null null C15orf40 null null {} null null null null {} null null null C15orf41 null null {} null null null null {} null null null C15orf43 null null {} null null null null {} null null null C15orf48 null null {} null null null null {} null null null C15orf57 null null {} null null null null {} null null null C15orf59 null null {} null null null null {} null null null C16orf13 null null {} null null null null {} null null null C16orf45 null null {} null null null null {} null null null C16orf54 UniProtKB UniProtKB {GO:0016021=GO_REF:0000037} Q6UWD8 Transmembrane protein C16orf54 protein 20130413 {GO:0016021=IEA} integral to membrane Human UniProtKB-KW:KW-0812 C16orf58 UniProtKB UniProtKB {GO:0016021=GO_REF:0000037} Q96GQ5 UPF0420 protein C16orf58 protein 20130413 {GO:0016021=IEA} integral to membrane Human UniProtKB-KW:KW-0812 C16orf59 null null {} null null null null {} null null null C16orf62 UniProtKB UniProtKB {GO:0016021=GO_REF:0000037} Q7Z3J2 UPF0505 protein C16orf62 protein 20130413 {GO:0016021=IEA} integral to membrane Human UniProtKB-KW:KW-0812 C16orf70 IntAct UniProtKB {GO:0005515=PMID:16713569} Q9BSU1 UPF0183 protein C16orf70 protein 20130415 {GO:0005515=IPI} protein binding Human UniProtKB:P54252 C16orf72 null null {} null null null null {} null null null C16orf74 null null {} null null null null {} null null null C16orf78 null null {} null null null null {} null null null C16orf80 PINC UniProtKB {GO:0005929=GO_REF:0000019, GO:0007275=PMID:8688464} Q9Y6A4 UPF0468 protein C16orf80 protein 20030904 {GO:0005929=IEA, GO:0007275=TAS} multicellular organismal development cilium Human C16orf87 null null {} null null null null {} null null null C16orf89 UniProtKB UniProtKB {GO:0005576=GO_REF:0000039} Q6UX73 UPF0764 protein C16orf89 protein 20130413 {GO:0005576=IEA} extracellular region Human UniProtKB-SubCell:SL-0243 C17orf49 InterPro UniProtKB {GO:0003682=GO_REF:0000002, GO:0003677=GO_REF:0000002} F8W1H0 Protein C17orf49 protein 20130413 {GO:0003682=IEA, GO:0003677=IEA} DNA binding, chromatin binding Human InterPro:IPR001005 C17orf53 null null {} null null null null {} null null null C17orf59 null null {} null null null null {} null null null C17orf62 IntAct UniProtKB {GO:0005515=PMID:20195357, GO:0016021=GO_REF:0000037} Q9BQA9 Uncharacterized protein C17orf62 protein 20130415 {GO:0005515=IPI, GO:0016021=IEA} integral to membrane protein binding Human UniProtKB:P14921 C17orf70 HPA UniProtKB {GO:0005737=GO_REF:0000052, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0045111=GO_REF:0000052} E7EVV8 Protein C17orf70 protein 20100326 {GO:0005737=IDA, GO:0005730=IDA, GO:0005634=IDA, GO:0045111=IDA} cytoplasm, intermediate filament cytoskeleton, nucleolus, nucleus Human C17orf75 UniProtKB UniProtKB {GO:0003674=GO_REF:0000015, GO:0005575=GO_REF:0000015, GO:0007283=GO_REF:0000029} Q9HAS0 Protein Njmu-R1 protein 20061026 {GO:0003674=ND, GO:0005575=ND, GO:0007283=NAS} spermatogenesis cellular_component molecular_function Human C17orf85 InterPro UniProtKB {GO:0000166=GO_REF:0000002} Q53F19 Uncharacterized protein C17orf85 protein 20130413 {GO:0000166=IEA} nucleotide binding Human InterPro:IPR012677 C18orf21 null null {} null null null null {} null null null C18orf25 null null {} null null null null {} null null null C18orf32 GOC UniProtKB {GO:0007165=PMID:12761501, GO:0004871=PMID:12761501, GO:0043123=PMID:12761501} Q8TCD1 UPF0729 protein C18orf32 protein 20130413 {GO:0007165=IMP, GO:0004871=IMP, GO:0043123=IMP} positive regulation of I-kappaB kinase/NF-kappaB cascade, signal transduction signal transducer activity Human C18orf54 null null {} null null null null {} null null null C18orf56 null null {} null null null null {} null null null C18orf8 null null {} null null null null {} null null null C19orf10 Reactome UniProtKB {GO:0005793=GO_REF:0000039, GO:0005788=Reactome:REACT_115959, GO:0005576=GO_REF:0000039, GO:0006987=Reactome:REACT_18368, GO:0044267=Reactome:REACT_17015, GO:0030968=Reactome:REACT_18356} Q969H8 UPF0556 protein C19orf10 protein 20130301 {GO:0005793=IEA, GO:0005788=TAS, GO:0005576=IEA, GO:0006987=TAS, GO:0044267=TAS, GO:0030968=TAS} activation of signaling protein activity involved in unfolded protein response, cellular protein metabolic process, endoplasmic reticulum unfolded protein response endoplasmic reticulum lumen, endoplasmic reticulum-Golgi intermediate compartment, extracellular region Human C19orf12 UniProtKB UniProtKB {GO:0008219=GO_REF:0000037, GO:0031966=GO_REF:0000039, GO:0016021=GO_REF:0000037} Q9NSK7 Protein C19orf12 protein 20130413 {GO:0008219=IEA, GO:0031966=IEA, GO:0016021=IEA} cell death integral to membrane, mitochondrial membrane Human UniProtKB-SubCell:SL-0171 C19orf18 UniProtKB UniProtKB {GO:0016021=GO_REF:0000037} Q8NEA5 Uncharacterized protein C19orf18 protein 20130413 {GO:0016021=IEA} integral to membrane Human UniProtKB-KW:KW-0812 C19orf21 null null {} null null null null {} null null null C19orf25 IntAct UniProtKB {GO:0005515=PMID:16189514} Q9UFG5 UPF0449 protein C19orf25 protein 20130415 {GO:0005515=IPI} protein binding Human UniProtKB:Q15834 C19orf33 InterPro UniProtKB {GO:0005634=GO_REF:0000002} K7EQG3 Protein C19orf33 protein 20130413 {GO:0005634=IEA} nucleus Human InterPro:IPR026621 C19orf40 InterPro UniProtKB {GO:0006281=GO_REF:0000002, GO:0043240=GO_REF:0000002} K7EKQ4 Protein C19orf40 protein 20130413 {GO:0006281=IEA, GO:0043240=IEA} DNA repair Fanconi anaemia nuclear complex Human InterPro:IPR026985 C19orf43 null null {} null null null null {} null null null C19orf44 null null {} null null null null {} null null null C19orf47 null null {} null null null null {} null null null C19orf52 null null {} null null null null {} null null null C19orf53 null null {} null null null null {} null null null C19orf54 null null {} null null null null {} null null null C19orf55 null null {} null null null null {} null null null C19orf57 IntAct UniProtKB {GO:0005515=PMID:19060904, GO:0003674=GO_REF:0000015, GO:0007275=PMID:8228263, GO:0005575=GO_REF:0000015} Q0VDD7 Uncharacterized protein C19orf57 protein 20130415 {GO:0005515=IPI, GO:0003674=ND, GO:0007275=NAS, GO:0005575=ND} multicellular organismal development cellular_component molecular_function, protein binding Human UniProtKB:Q13155 C19orf60 IntAct UniProtKB {GO:0005515=PMID:19060904} Q96EN9 Uncharacterized protein C19orf60 protein 20130415 {GO:0005515=IPI} protein binding Human UniProtKB:Q99750 C19orf66 null null {} null null null null {} null null null C19orf68 IntAct UniProtKB {GO:0005515=PMID:20195357} Q86XI8 Uncharacterized protein C19orf68 protein 20130415 {GO:0005515=IPI} protein binding Human UniProtKB:P17275 C19orf70 null null {} null null null null {} null null null C19orf80 IntAct UniProtKB {GO:0005515=PMID:21988832, GO:0010954=PMID:23150577, GO:0070328=PMID:23150577, GO:0005576=GO_REF:0000039, GO:0050746=PMID:23150577} Q6UXH0 Hepatocellular carcinoma-associated protein TD26 protein 20130415 {GO:0005515=IPI, GO:0010954=IDA, GO:0070328=IGI, GO:0005576=IEA, GO:0050746=IMP} positive regulation of protein processing, regulation of lipoprotein metabolic process, triglyceride homeostasis extracellular region protein binding Human UniProtKB:Q96PM5 C1D HPA UniProtKB {GO:0005515=PMID:17412707, GO:0016922=GO_REF:0000019, GO:0000460=PMID:17412707, GO:0003714=GO_REF:0000019, GO:0003723=PMID:17412707, GO:0005730=GO_REF:0000052, GO:0006915=GO_REF:0000037, GO:0005634=GO_REF:0000052, GO:0003677=GO_REF:0000019, GO:0006351=GO_REF:0000037, GO:0005739=GO_REF:0000052, GO:0017053=GO_REF:0000019, GO:0000176=PMID:17412707, GO:0045892=GO_REF:0000019} Q13901 Nuclear nucleic acid-binding protein C1D protein 20111111 {GO:0005515=IPI, GO:0016922=IEA, GO:0000460=IMP, GO:0003714=IEA, GO:0003723=IDA, GO:0005730=IDA, GO:0006915=IEA, GO:0005634=IDA, GO:0003677=IEA, GO:0006351=IEA, GO:0005739=IDA, GO:0017053=IEA, GO:0000176=TAS, GO:0045892=IEA} apoptotic process, maturation of 5.8S rRNA, negative regulation of transcription, DNA-dependent, transcription, DNA-dependent mitochondrion, nuclear exosome (RNase complex), nucleolus, nucleus, transcriptional repressor complex DNA binding, RNA binding, ligand-dependent nuclear receptor binding, protein binding, transcription corepressor activity Human C1GALT1 Reactome UniProtKB {GO:0000139=Reactome:REACT_116072, GO:0001822=PMID:17228361, GO:0016266=Reactome:REACT_115606, GO:0016263=PMID:11677243, GO:0016021=PMID:11677243, GO:0001525=PMID:17228361, GO:0044267=Reactome:REACT_17015, GO:0046872=GO_REF:0000037, GO:0030154=GO_REF:0000037, GO:0043687=Reactome:REACT_22161} Q9NS00 Glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1 protein 20111104 {GO:0000139=TAS, GO:0001822=IMP, GO:0016266=TAS, GO:0016263=IDA, GO:0016021=IDA, GO:0001525=IMP, GO:0044267=TAS, GO:0046872=IEA, GO:0030154=IEA, GO:0043687=TAS} O-glycan processing, angiogenesis, cell differentiation, cellular protein metabolic process, kidney development, post-translational protein modification Golgi membrane, integral to membrane glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase activity, metal ion binding Human C1GALT1C1 Reactome UniProtKB {GO:0004653=Reactome:REACT_115586, GO:0000139=Reactome:REACT_116072, GO:0016266=Reactome:REACT_115606, GO:0016021=GO_REF:0000037, GO:0044267=Reactome:REACT_17015, GO:0043687=Reactome:REACT_22161} Q96EU7 C1GALT1-specific chaperone 1 protein 20100721 {GO:0004653=TAS, GO:0000139=TAS, GO:0016266=TAS, GO:0016021=IEA, GO:0044267=TAS, GO:0043687=TAS} O-glycan processing, cellular protein metabolic process, post-translational protein modification Golgi membrane, integral to membrane polypeptide N-acetylgalactosaminyltransferase activity Human C1orf105 null null {} null null null null {} null null null C1orf109 null null {} null null null null {} null null null C1orf110 null null {} null null null null {} null null null C1orf111 null null {} null null null null {} null null null C1orf112 null null {} null null null null {} null null null C1orf115 UniProtKB UniProtKB {GO:0016021=GO_REF:0000037} Q9H7X2 Uncharacterized protein C1orf115 protein 20130413 {GO:0016021=IEA} integral to membrane Human UniProtKB-KW:KW-0812 C1orf116 null null {} null null null null {} null null null C1orf122 null null {} null null null null {} null null null C1orf123 UniProtKB UniProtKB {GO:0008150=GO_REF:0000015, GO:0003674=GO_REF:0000015, GO:0005575=GO_REF:0000015} Q9NWV4 UPF0587 protein C1orf123 protein 20080829 {GO:0008150=ND, GO:0003674=ND, GO:0005575=ND} biological_process cellular_component molecular_function Human C1orf131 null null {} null null null null {} null null null C1orf174 UniProtKB UniProtKB {GO:0005634=GO_REF:0000039} Q8IYL3 UPF0688 protein C1orf174 protein 20130413 {GO:0005634=IEA} nucleus Human UniProtKB-SubCell:SL-0191 C1orf198 UniProtKB UniProtKB {GO:0005737=GO_REF:0000039} Q9H425 Uncharacterized protein C1orf198 protein 20130413 {GO:0005737=IEA} cytoplasm Human UniProtKB-SubCell:SL-0086 C1orf216 null null {} null null null null {} null null null C1orf27 null null {} null null null null {} null null null C1orf35 null null {} null null null null {} null null null C1orf43 UniProtKB UniProtKB {GO:0050662=GO_REF:0000002, GO:0016021=GO_REF:0000037, GO:0016616=GO_REF:0000002} Q9BWL3 Uncharacterized protein C1orf43 protein 20130413 {GO:0050662=IEA, GO:0016021=IEA, GO:0016616=IEA} integral to membrane coenzyme binding, oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor Human UniProtKB-KW:KW-0812 C1orf50 null null {} null null null null {} null null null C1orf51 null null {} null null null null {} null null null C1orf52 null null {} null null null null {} null null null C1orf61 UniProtKB UniProtKB {GO:0005634=GO_REF:0000039} Q13536 Protein CROC-4 protein 20130413 {GO:0005634=IEA} nucleus Human UniProtKB-SubCell:SL-0191 C1orf63 null null {} null null null null {} null null null C1orf64 null null {} null null null null {} null null null C1orf65 null null {} null null null null {} null null null C1orf68 null null {} null null null null {} null null null C1orf74 null null {} null null null null {} null null null C1orf86 null null {} null null null null {} null null null C1orf87 InterPro UniProtKB {GO:0005509=GO_REF:0000002} Q8N0U7 Uncharacterized protein C1orf87 protein 20130413 {GO:0005509=IEA} calcium ion binding Human InterPro:IPR011992 C1orf94 IntAct UniProtKB {GO:0005515=PMID:23088713} Q6P1W5 Uncharacterized protein C1orf94 protein 20130415 {GO:0005515=IPI} protein binding Human UniProtKB:P09022 C1QA IntAct UniProtKB {GO:0005515=PMID:12960167, GO:0006956=Reactome:REACT_8024, GO:0005581=GO_REF:0000037, GO:0045087=Reactome:REACT_6802, GO:0006958=Reactome:REACT_7956, GO:0007267=PMID:9461517, GO:0005576=Reactome:REACT_8002, GO:0005602=PMID:9461517} P02745 Complement C1q subcomponent subunit A protein 20130415 {GO:0005515=IPI, GO:0006956=TAS, GO:0005581=IEA, GO:0045087=TAS, GO:0006958=TAS, GO:0007267=TAS, GO:0005576=TAS, GO:0005602=TAS} cell-cell signaling, complement activation, complement activation, classical pathway, innate immune response collagen, complement component C1 complex, extracellular region protein binding Human UniProtKB:P02746 C1QB IntAct UniProtKB {GO:0005515=PMID:12960167, GO:0006956=Reactome:REACT_8024, GO:0048839=GO_REF:0000019, GO:0005581=GO_REF:0000037, GO:0045087=Reactome:REACT_6802, GO:0006958=Reactome:REACT_7956, GO:0005576=Reactome:REACT_8002, GO:0005602=PMID:1706597, GO:0042803=GO_REF:0000019} P02746 Complement C1q subcomponent subunit B protein 20130415 {GO:0005515=IPI, GO:0006956=TAS, GO:0048839=IEA, GO:0005581=IEA, GO:0045087=TAS, GO:0006958=TAS, GO:0005576=TAS, GO:0005602=TAS, GO:0042803=IEA} complement activation, complement activation, classical pathway, innate immune response, inner ear development collagen, complement component C1 complex, extracellular region protein binding, protein homodimerization activity Human UniProtKB:P02745 C1QBP IntAct UniProtKB {GO:0008380=GO_REF:0000037, GO:0005515=PMID:22238231, GO:0050687=PMID:19164550, GO:0051897=PMID:16177118, GO:0030449=PMID:8195709, GO:0030984=PMID:8662673, GO:0048025=PMID:10022843, GO:0005886=Reactome:REACT_2239, GO:0070131=GO_REF:0000024, GO:0005634=PMID:15243141, GO:0003729=GO_REF:0000024, GO:0005615=GO_REF:0000019, GO:2000510=PMID:16140380, GO:0005829=PMID:15243141, GO:0005739=PMID:19164550, GO:0006955=PMID:8195709, GO:0005737=GO_REF:0000024, GO:1900026=PMID:11859136, GO:0005540=PMID:8567680, GO:0005759=GO_REF:0000039, GO:0039536=PMID:19164550, GO:0006958=GO_REF:0000037, GO:0005080=GO_REF:0000019, GO:0097177=GO_REF:0000024, GO:0032689=PMID:17881511, GO:1901165=PMID:20810993, GO:0006397=GO_REF:0000037, GO:0043065=PMID:15031724, GO:0042256=PMID:21536856, GO:0009986=PMID:17881511, GO:0003714=PMID:15243141, GO:0001849=PMID:8195709, GO:0005730=GO_REF:0000039, GO:0006915=GO_REF:0000037, GO:0039534=PMID:19164550, GO:0000122=PMID:15243141, GO:0014065=PMID:16177118, GO:0006351=GO_REF:0000037, GO:0045785=PMID:20810993, GO:0031690=GO_REF:0000024, GO:0016020=PMID:8662673, GO:0007596=Reactome:REACT_2051, GO:0032695=PMID:17881511, GO:0007597=Reactome:REACT_326, GO:0045087=GO_REF:0000037, GO:0019048=GO_REF:0000037, GO:0090023=PMID:9461517, GO:0008134=PMID:15243141} Q07021 Complement component 1 Q subcomponent-binding protein, mitochondrial protein 20130415 {GO:0008380=IEA, GO:0005515=IPI, GO:0050687=IMP, GO:0051897=IMP, GO:0030449=IDA, GO:0030984=IDA, GO:0048025=IDA, GO:0005886=TAS, GO:0070131=ISS, GO:0005634=IDA, GO:0003729=ISS, GO:0005615=IEA, GO:2000510=IMP, GO:0005829=IDA, GO:0005739=IDA, GO:0006955=TAS, GO:0005737=ISS, GO:1900026=IMP, GO:0005540=IDA, GO:0005759=IEA, GO:0039536=IDA, GO:0006958=IEA, GO:0005080=IEA, GO:0097177=ISS, GO:0032689=IDA, GO:1901165=IMP, GO:0006397=IEA, GO:0043065=IMP, GO:0042256=IMP, GO:0009986=IDA, GO:0003714=IDA, GO:0001849=IDA, GO:0005730=IEA, GO:0006915=IEA, GO:0039534=IDA, GO:0000122=IDA, GO:0014065=IMP, GO:0006351=IEA, GO:0045785=IMP, GO:0031690=ISS, GO:0016020=IDA, GO:0007596=TAS, GO:0032695=IDA, GO:0007597=TAS, GO:0045087=IEA, GO:0019048=IEA, GO:0090023=IDA, GO:0008134=IDA} RNA splicing, apoptotic process, blood coagulation, blood coagulation, intrinsic pathway, complement activation, classical pathway, immune response, innate immune response, mRNA processing, mature ribosome assembly, negative regulation of MDA-5 signaling pathway, negative regulation of RIG-I signaling pathway, negative regulation of defense response to virus, negative regulation of interferon-gamma production, negative regulation of interleukin-12 production, negative regulation of mRNA splicing, via spliceosome, negative regulation of transcription from RNA polymerase II promoter, phosphatidylinositol 3-kinase cascade, positive regulation of apoptotic process, positive regulation of cell adhesion, positive regulation of dendritic cell chemotaxis, positive regulation of mitochondrial translation, positive regulation of neutrophil chemotaxis, positive regulation of protein kinase B signaling cascade, positive regulation of substrate adhesion-dependent cell spreading, positive regulation of trophoblast cell migration, regulation of complement activation, transcription, DNA-dependent, virus-host interaction cell surface, cytoplasm, cytosol, extracellular space, membrane, mitochondrial matrix, mitochondrion, nucleolus, nucleus, plasma membrane adrenergic receptor binding, complement component C1q binding, hyaluronic acid binding, kininogen binding, mRNA binding, mitochondrial ribosome binding, protein binding, protein kinase C binding, transcription corepressor activity, transcription factor binding Human UniProtKB:O40955:PRO_0000240177 C1QC BHF-UCL UniProtKB {GO:0006956=Reactome:REACT_8024, GO:0006955=PMID:9777412, GO:0005581=GO_REF:0000037, GO:0045087=Reactome:REACT_6802, GO:0006958=Reactome:REACT_7956, GO:0030853=PMID:10961870, GO:0005576=Reactome:REACT_8002, GO:0045650=PMID:10961870} P02747 Complement C1q subcomponent subunit C protein 20080926 {GO:0006956=TAS, GO:0006955=NAS, GO:0005581=IEA, GO:0045087=TAS, GO:0006958=TAS, GO:0030853=IDA, GO:0005576=TAS, GO:0045650=IDA} complement activation, complement activation, classical pathway, immune response, innate immune response, negative regulation of granulocyte differentiation, negative regulation of macrophage differentiation collagen, extracellular region Human C1QL1 UniProtKB UniProtKB {GO:0003674=GO_REF:0000015, GO:0005737=GO_REF:0000019, GO:0005581=GO_REF:0000037, GO:0007626=PMID:9878755, GO:0005575=GO_REF:0000015} O75973 C1q-related factor protein 20061026 {GO:0003674=ND, GO:0005737=IEA, GO:0005581=IEA, GO:0007626=NAS, GO:0005575=ND} locomotory behavior cellular_component, collagen, cytoplasm molecular_function Human C1QL3 ENSEMBL UniProtKB {GO:0005581=GO_REF:0000037, GO:0050807=GO_REF:0000019} Q5VWW1 Complement C1q-like protein 3 protein 20130413 {GO:0005581=IEA, GO:0050807=IEA} regulation of synapse organization collagen Human Ensembl:ENSMUSP00000056188 C1QTNF1 ENSEMBL UniProtKB {GO:0070208=GO_REF:0000019, GO:0051897=GO_REF:0000019, GO:0005581=GO_REF:0000037, GO:0051260=GO_REF:0000019, GO:0043410=GO_REF:0000019, GO:0005615=GO_REF:0000019, GO:0010906=GO_REF:0000019} Q9BXJ1 Complement C1q tumor necrosis factor-related protein 1 protein 20130413 {GO:0070208=IEA, GO:0051897=IEA, GO:0005581=IEA, GO:0051260=IEA, GO:0043410=IEA, GO:0005615=IEA, GO:0010906=IEA} positive regulation of MAPK cascade, positive regulation of protein kinase B signaling cascade, protein heterotrimerization, protein homooligomerization, regulation of glucose metabolic process collagen, extracellular space Human Ensembl:ENSMUSP00000017590 C1QTNF5 UniProtKB UniProtKB {GO:0005581=GO_REF:0000037} Q9BXJ0 Complement C1q tumor necrosis factor-related protein 5 protein 20130413 {GO:0005581=IEA} collagen Human UniProtKB-KW:KW-0176 C1R IntAct UniProtKB {GO:0005515=PMID:12788922, GO:0006956=Reactome:REACT_8024, GO:0006955=PMID:737019, GO:0004252=Reactome:REACT_7978, GO:0045087=Reactome:REACT_6802, GO:0006958=Reactome:REACT_7956, GO:0005509=GO_REF:0000002, GO:0006508=GO_REF:0000037, GO:0008236=PMID:2834284, GO:0005576=Reactome:REACT_8002} P00736 Complement C1r subcomponent protein 20130415 {GO:0005515=IPI, GO:0006956=TAS, GO:0006955=TAS, GO:0004252=EXP, GO:0045087=TAS, GO:0006958=TAS, GO:0005509=IEA, GO:0006508=IEA, GO:0008236=TAS, GO:0005576=TAS} complement activation, complement activation, classical pathway, immune response, innate immune response, proteolysis extracellular region calcium ion binding, protein binding, serine-type endopeptidase activity, serine-type peptidase activity Human UniProtKB:P09871 C1RL ENSEMBL UniProtKB {GO:0004252=GO_REF:0000002, GO:0045087=GO_REF:0000037, GO:0006958=GO_REF:0000037, GO:0006508=GO_REF:0000037, GO:0005615=GO_REF:0000019} Q9NZP8 Complement C1r subcomponent-like protein protein 20130413 {GO:0004252=IEA, GO:0045087=IEA, GO:0006958=IEA, GO:0006508=IEA, GO:0005615=IEA} complement activation, classical pathway, innate immune response, proteolysis extracellular space serine-type endopeptidase activity Human Ensembl:ENSMUSP00000042883 C1S IntAct UniProtKB {GO:0005515=PMID:12788922, GO:0006956=Reactome:REACT_8024, GO:0004252=PMID:11527969, GO:0045087=Reactome:REACT_6802, GO:0006958=Reactome:REACT_7956, GO:0005509=GO_REF:0000002, GO:0006508=GO_REF:0000037, GO:0005576=Reactome:REACT_8002, GO:0042802=PMID:12788922} P09871 Complement C1s subcomponent protein 20130415 {GO:0005515=IPI, GO:0006956=TAS, GO:0004252=IDA, GO:0045087=TAS, GO:0006958=TAS, GO:0005509=IEA, GO:0006508=IEA, GO:0005576=TAS, GO:0042802=IPI} complement activation, complement activation, classical pathway, innate immune response, proteolysis extracellular region calcium ion binding, identical protein binding, protein binding, serine-type endopeptidase activity Human UniProtKB:P09871 C2 Reactome UniProtKB {GO:0030449=Reactome:REACT_118707, GO:0006956=Reactome:REACT_8024, GO:0004252=GO_REF:0000002, GO:0045087=Reactome:REACT_6802, GO:0006958=GO_REF:0000037, GO:0006508=GO_REF:0000037, GO:0005576=Reactome:REACT_118782, GO:0005615=PMID:8621452} P06681 Complement C2 protein 20101026 {GO:0030449=TAS, GO:0006956=TAS, GO:0004252=IEA, GO:0045087=TAS, GO:0006958=IEA, GO:0006508=IEA, GO:0005576=TAS, GO:0005615=TAS} complement activation, complement activation, classical pathway, innate immune response, proteolysis, regulation of complement activation extracellular region, extracellular space serine-type endopeptidase activity Human C20orf111 null null {} null null null null {} null null null C20orf194 null null {} null null null null {} null null null C20orf195 null null {} null null null null {} null null null C20orf196 null null {} null null null null {} null null null C20orf24 UniProtKB UniProtKB {GO:0008150=GO_REF:0000015, GO:0003674=GO_REF:0000015, GO:0005575=GO_REF:0000015} Q9BUV8 Uncharacterized protein C20orf24 protein 20061026 {GO:0008150=ND, GO:0003674=ND, GO:0005575=ND} biological_process cellular_component molecular_function Human C20orf26 null null {} null null null null {} null null null C20orf27 BHF-UCL UniProtKB {GO:0003674=GO_REF:0000015, GO:0008150=GO_REF:0000015, GO:0005575=GO_REF:0000015} Q9GZN8 UPF0687 protein C20orf27 protein 20120716 {GO:0003674=ND, GO:0008150=ND, GO:0005575=ND} biological_process cellular_component molecular_function Human C20orf96 null null {} null null null null {} null null null C21orf2 UniProtKB UniProtKB {GO:0008150=GO_REF:0000015, GO:0003674=GO_REF:0000015, GO:0005737=PMID:21834987, GO:0005886=PMID:21834987, GO:0008360=PMID:21834987, GO:0007010=PMID:21834987, GO:0060271=GO_REF:0000019} O43822 Protein C21orf2 protein 20110926 {GO:0008150=ND, GO:0003674=ND, GO:0005737=IDA, GO:0005886=IDA, GO:0008360=IMP, GO:0007010=IMP, GO:0060271=IEA} biological_process, cilium morphogenesis, cytoskeleton organization, regulation of cell shape cytoplasm, plasma membrane molecular_function Human C21orf33 RefGenome UniProtKB {GO:0005739=GO_REF:0000033} P30042 ES1 protein homolog, mitochondrial protein 20110112 {GO:0005739=IBA} mitochondrion Human PANTHER:PTN000027433 C21orf58 null null {} null null null null {} null null null C21orf59 UniProtKB UniProtKB {GO:0005634=PMID:16780588, GO:0005829=PMID:16780588} P57076 Uncharacterized protein C21orf59 protein 20081007 {GO:0005634=IDA, GO:0005829=IDA} cytosol, nucleus Human C21orf91 null null {} null null null null {} null null null C22orf28 UniProtKB UniProtKB {GO:0006388=PMID:21311021, GO:0005737=GO_REF:0000039, GO:0007160=PMID:15163412, GO:0017166=PMID:15163412, GO:0034446=PMID:15163412, GO:0003972=PMID:21311021, GO:0001890=GO_REF:0000019, GO:0001701=GO_REF:0000019, GO:0005524=GO_REF:0000037, GO:0072669=PMID:21311021, GO:0046872=GO_REF:0000037} Q9Y3I0 tRNA-splicing ligase RtcB homolog protein 20110222 {GO:0006388=IDA, GO:0005737=IEA, GO:0007160=NAS, GO:0017166=IPI, GO:0034446=NAS, GO:0003972=IDA, GO:0001890=IEA, GO:0001701=IEA, GO:0005524=IEA, GO:0072669=IDA, GO:0046872=IEA} cell-matrix adhesion, in utero embryonic development, placenta development, substrate adhesion-dependent cell spreading, tRNA splicing, via endonucleolytic cleavage and ligation cytoplasm, tRNA-splicing ligase complex ATP binding, RNA ligase (ATP) activity, metal ion binding, vinculin binding Human C22orf39 null null {} null null null null {} null null null C22orf46 UniProtKB UniProtKB {GO:0005576=GO_REF:0000039} C9J442 Uncharacterized protein C22orf46 protein 20130413 {GO:0005576=IEA} extracellular region Human UniProtKB-SubCell:SL-0243 C2CD2 UniProtKB UniProtKB {GO:0005634=PMID:16780588, GO:0005576=GO_REF:0000039, GO:0005829=PMID:16780588} Q9Y426 C2 domain-containing protein 2 protein 20081007 {GO:0005634=IDA, GO:0005576=IEA, GO:0005829=IDA} cytosol, extracellular region, nucleus Human C2CD2L UniProtKB UniProtKB {GO:0008150=GO_REF:0000015, GO:0003674=GO_REF:0000015, GO:0005575=GO_REF:0000015, GO:0016021=GO_REF:0000037} O14523 C2 domain-containing protein 2-like protein 20061026 {GO:0008150=ND, GO:0003674=ND, GO:0005575=ND, GO:0016021=IEA} biological_process cellular_component, integral to membrane molecular_function Human C2CD3 UniProtKB UniProtKB {GO:0030162=GO_REF:0000019, GO:0021997=GO_REF:0000019, GO:0001947=GO_REF:0000019, GO:0042384=GO_REF:0000019, GO:0005813=PMID:21399614, GO:0016485=GO_REF:0000019, GO:0008589=GO_REF:0000019, GO:0007420=GO_REF:0000019, GO:0021915=GO_REF:0000019, GO:0005932=GO_REF:0000019, GO:0001701=GO_REF:0000019, GO:0042733=GO_REF:0000019} Q4AC94 C2 domain-containing protein 3 protein 20110517 {GO:0030162=IEA, GO:0021997=IEA, GO:0001947=IEA, GO:0042384=IEA, GO:0005813=IDA, GO:0016485=IEA, GO:0008589=IEA, GO:0007420=IEA, GO:0021915=IEA, GO:0005932=IEA, GO:0001701=IEA, GO:0042733=IEA} brain development, cilium assembly, embryonic digit morphogenesis, heart looping, in utero embryonic development, neural plate axis specification, neural tube development, protein processing, regulation of proteolysis, regulation of smoothened signaling pathway centrosome, microtubule basal body Human C2orf27B null null {} null null null null {} null null null C2orf42 null null {} null null null null {} null null null C2orf43 null null {} null null null null {} null null null C2orf44 null null {} null null null null {} null null null C2orf47 UniProtKB UniProtKB {GO:0005739=GO_REF:0000039} Q8WWC4 Uncharacterized protein C2orf47, mitochondrial protein 20130413 {GO:0005739=IEA} mitochondrion Human UniProtKB-SubCell:SL-0173 C2orf49 UniProtKB UniProtKB {GO:0003674=GO_REF:0000015, GO:0008150=GO_REF:0000015, GO:0048598=GO_REF:0000002, GO:0072669=PMID:21311021} Q9BVC5 Ashwin protein 20110222 {GO:0003674=ND, GO:0008150=ND, GO:0048598=IEA, GO:0072669=IDA} biological_process, embryonic morphogenesis tRNA-splicing ligase complex molecular_function Human C2orf50 null null {} null null null null {} null null null C2orf57 null null {} null null null null {} null null null C2orf62 null null {} null null null null {} null null null C2orf68 null null {} null null null null {} null null null C2orf73 null null {} null null null null {} null null null C2orf74 UniProtKB UniProtKB {GO:0016021=GO_REF:0000037} A8MZ97 Uncharacterized protein C2orf74 protein 20130413 {GO:0016021=IEA} integral to membrane Human UniProtKB-KW:KW-0812 C2orf76 null null {} null null null null {} null null null C2orf88 UniProtKB UniProtKB {GO:0005886=GO_REF:0000039} Q9BSF0 Small membrane A-kinase anchor protein protein 20130413 {GO:0005886=IEA} plasma membrane Human UniProtKB-SubCell:SL-0039 C3 BHF-UCL UniProtKB {GO:0005515=PMID:16530040, GO:0030449=Reactome:REACT_118707, GO:0004866=GO_REF:0000002, GO:0005886=Reactome:REACT_118841, GO:0001970=GO_REF:0000019, GO:0005615=GO_REF:0000002, GO:0006957=Reactome:REACT_8001, GO:0006956=Reactome:REACT_8024, GO:0050766=GO_REF:0000019, GO:0006955=PMID:4097977, GO:0006954=GO_REF:0000037, GO:0006958=GO_REF:0000037, GO:0006631=GO_REF:0000037, GO:0001798=GO_REF:0000019, GO:0045745=PMID:15833747, GO:0005102=PMID:9164946, GO:0010884=PMID:9555951, GO:0005576=Reactome:REACT_118844, GO:0010866=PMID:10432298, GO:0010575=PMID:16452172, GO:0031715=PMID:15833747, GO:0045766=GO_REF:0000019, GO:0010828=PMID:15833747, GO:0007165=PMID:10085065, GO:0007186=PMID:9164946, GO:0045087=Reactome:REACT_6802, GO:0050776=Reactome:REACT_11152, GO:0001934=PMID:15833747} P01024 Complement C3 protein 20100104 {GO:0005515=IPI, GO:0030449=TAS, GO:0004866=IEA, GO:0005886=TAS, GO:0001970=IEA, GO:0005615=IEA, GO:0006957=TAS, GO:0006956=TAS, GO:0050766=IEA, GO:0006955=TAS, GO:0006954=IEA, GO:0006958=IEA, GO:0006631=IEA, GO:0001798=IEA, GO:0045745=IDA, GO:0005102=TAS, GO:0010884=IDA, GO:0005576=TAS, GO:0010866=IDA, GO:0010575=IDA, GO:0031715=IDA, GO:0045766=IEA, GO:0010828=IDA, GO:0007165=TAS, GO:0007186=TAS, GO:0045087=TAS, GO:0050776=TAS, GO:0001934=IDA} G-protein coupled receptor signaling pathway, complement activation, complement activation, alternative pathway, complement activation, classical pathway, fatty acid metabolic process, immune response, inflammatory response, innate immune response, positive regulation of G-protein coupled receptor protein signaling pathway, positive regulation of activation of membrane attack complex, positive regulation of angiogenesis, positive regulation of glucose transport, positive regulation of lipid storage, positive regulation of phagocytosis, positive regulation of protein phosphorylation, positive regulation of type IIa hypersensitivity, positive regulation vascular endothelial growth factor production, regulation of complement activation, regulation of immune response, regulation of triglyceride biosynthetic process, signal transduction extracellular region, extracellular space, plasma membrane C5L2 anaphylatoxin chemotactic receptor binding, endopeptidase inhibitor activity, protein binding, receptor binding Human C3AR1 Reactome UniProtKB {GO:0005886=Reactome:REACT_22289, GO:0004943=GO_REF:0000002, GO:0004930=PMID:10571060, GO:0008015=PMID:8765043, GO:0010575=GO_REF:0000019, GO:0007204=PMID:10571060, GO:0045766=GO_REF:0000019, GO:0004982=GO_REF:0000002, GO:0006954=PMID:8765043, GO:0007186=PMID:8898085, GO:0006935=GO_REF:0000037, GO:0004435=PMID:8765043, GO:0005887=PMID:8702752, GO:0010759=GO_REF:0000019, GO:0090023=GO_REF:0000019, GO:0016021=GO_REF:0000038, GO:0004876=PMID:8765043} Q16581 C3a anaphylatoxin chemotactic receptor protein 20091026 {GO:0005886=TAS, GO:0004943=IEA, GO:0004930=IGI, GO:0008015=TAS, GO:0010575=IEA, GO:0007204=IGI, GO:0045766=IEA, GO:0004982=IEA, GO:0006954=TAS, GO:0007186=TAS, GO:0006935=IEA, GO:0004435=TAS, GO:0005887=TAS, GO:0010759=IEA, GO:0090023=IEA, GO:0016021=IEA, GO:0004876=TAS} G-protein coupled receptor signaling pathway, blood circulation, chemotaxis, elevation of cytosolic calcium ion concentration, inflammatory response, positive regulation of angiogenesis, positive regulation of macrophage chemotaxis, positive regulation of neutrophil chemotaxis, positive regulation vascular endothelial growth factor production integral to membrane, integral to plasma membrane, plasma membrane C3a anaphylatoxin receptor activity, G-protein coupled receptor activity, N-formyl peptide receptor activity, complement component C3a receptor activity, phosphatidylinositol phospholipase C activity Human C3orf17 UniProtKB UniProtKB {GO:0016021=GO_REF:0000037} Q6NW34 Uncharacterized protein C3orf17 protein 20130413 {GO:0016021=IEA} integral to membrane Human UniProtKB-KW:KW-0812 C3orf20 LIFEdb UniProtKB {GO:0005737=GO_REF:0000054, GO:0016021=GO_REF:0000037} Q8ND61 Uncharacterized protein C3orf20 protein 20100607 {GO:0005737=IDA, GO:0016021=IEA} cytoplasm, integral to membrane Human C3orf33 UniProtKB UniProtKB {GO:0016021=GO_REF:0000037, GO:0003676=GO_REF:0000002} Q6P1S2 Uncharacterized protein C3orf33 protein 20130413 {GO:0016021=IEA, GO:0003676=IEA} integral to membrane nucleic acid binding Human UniProtKB-KW:KW-0812 C3orf36 null null {} null null null null {} null null null C3orf37 null null {} null null null null {} null null null C3orf38 UniProtKB UniProtKB {GO:0006915=GO_REF:0000037} Q5JPI3 Uncharacterized protein C3orf38 protein 20130413 {GO:0006915=IEA} apoptotic process Human UniProtKB-KW:KW-0053 C3orf52 null null {} null null null null {} null null null C3orf62 null null {} null null null null {} null null null C4A Reactome UniProtKB {GO:0030449=Reactome:REACT_118707, GO:0006956=Reactome:REACT_8024, GO:0006954=GO_REF:0000037, GO:0005886=Reactome:REACT_118719, GO:0004866=GO_REF:0000002, GO:0045087=Reactome:REACT_6802, GO:0006958=GO_REF:0000037, GO:0005576=Reactome:REACT_118782, GO:0005615=GO_REF:0000002} P0C0L4 Complement C4-A protein 20101026 {GO:0030449=TAS, GO:0006956=TAS, GO:0006954=IEA, GO:0005886=TAS, GO:0004866=IEA, GO:0045087=TAS, GO:0006958=IEA, GO:0005576=TAS, GO:0005615=IEA} complement activation, complement activation, classical pathway, inflammatory response, innate immune response, regulation of complement activation extracellular region, extracellular space, plasma membrane endopeptidase inhibitor activity Human C4B Reactome UniProtKB {GO:0030449=Reactome:REACT_118707, GO:0006956=Reactome:REACT_8024, GO:0006954=GO_REF:0000037, GO:0005886=Reactome:REACT_118719, GO:0004866=GO_REF:0000002, GO:0045087=Reactome:REACT_6802, GO:0006958=GO_REF:0000037, GO:0005576=Reactome:REACT_118782, GO:0005615=GO_REF:0000002} P0C0L5 Complement C4-B protein 20101026 {GO:0030449=TAS, GO:0006956=TAS, GO:0006954=IEA, GO:0005886=TAS, GO:0004866=IEA, GO:0045087=TAS, GO:0006958=IEA, GO:0005576=TAS, GO:0005615=IEA} complement activation, complement activation, classical pathway, inflammatory response, innate immune response, regulation of complement activation extracellular region, extracellular space, plasma membrane endopeptidase inhibitor activity Human C4BPA HPA UniProtKB {GO:0005515=PMID:16330538, GO:0030449=Reactome:REACT_118707, GO:0005737=GO_REF:0000052, GO:0005886=Reactome:REACT_118836, GO:0045087=Reactome:REACT_6802, GO:0006958=GO_REF:0000037, GO:0005576=PMID:14718574} P04003 C4b-binding protein alpha chain protein 20101115 {GO:0005515=IPI, GO:0030449=TAS, GO:0005737=IDA, GO:0005886=TAS, GO:0045087=TAS, GO:0006958=IEA, GO:0005576=NAS} complement activation, classical pathway, innate immune response, regulation of complement activation cytoplasm, extracellular region, plasma membrane protein binding Human C4BPB Reactome UniProtKB {GO:0030449=Reactome:REACT_118707, GO:0005886=Reactome:REACT_118836, GO:0007596=PMID:8325877, GO:0045087=Reactome:REACT_6802, GO:0006958=GO_REF:0000037, GO:0005576=PMID:14718574} P20851 C4b-binding protein beta chain protein 20101026 {GO:0030449=TAS, GO:0005886=TAS, GO:0007596=TAS, GO:0045087=TAS, GO:0006958=IEA, GO:0005576=NAS} blood coagulation, complement activation, classical pathway, innate immune response, regulation of complement activation extracellular region, plasma membrane Human C4orf17 null null {} null null null null {} null null null C4orf21 InterPro UniProtKB {GO:0008270=GO_REF:0000002} I3L0G6 Uncharacterized protein C4orf21 protein 20130413 {GO:0008270=IEA} zinc ion binding Human InterPro:IPR010666 C4orf22 null null {} null null null null {} null null null C4orf27 LIFEdb UniProtKB {GO:0005634=GO_REF:0000054} Q9NWY4 UPF0609 protein C4orf27 protein 20100607 {GO:0005634=IDA} nucleus Human C4orf29 UniProtKB UniProtKB {GO:0005576=GO_REF:0000039} Q0P651 Uncharacterized protein C4orf29 protein 20130413 {GO:0005576=IEA} extracellular region Human UniProtKB-SubCell:SL-0243 C4orf32 UniProtKB UniProtKB {GO:0016021=GO_REF:0000037} Q8N8J7 Uncharacterized protein C4orf32 protein 20130413 {GO:0016021=IEA} integral to membrane Human UniProtKB-KW:KW-0812 C4orf36 null null {} null null null null {} null null null C4orf46 null null {} null null null null {} null null null C5 BHF-UCL UniProtKB {GO:0004866=GO_REF:0000002, GO:0005615=GO_REF:0000002, GO:0010760=PMID:14566334, GO:0006957=GO_REF:0000037, GO:0006956=Reactome:REACT_7972, GO:0000187=PMID:7649993, GO:0006954=PMID:8759757, GO:0050921=GO_REF:0000019, GO:0006935=GO_REF:0000019, GO:0005579=GO_REF:0000037, GO:0019835=GO_REF:0000037, GO:0006958=GO_REF:0000037, GO:0090197=PMID:14566334, GO:0008009=PMID:10820279, GO:0002523=GO_REF:0000019, GO:0006874=GO_REF:0000019, GO:0005102=PMID:9590258, GO:0006950=PMID:9590258, GO:0005576=Reactome:REACT_24998, GO:0006917=GO_REF:0000019, GO:0042593=GO_REF:0000019, GO:0031714=GO_REF:0000019, GO:0010700=GO_REF:0000019, GO:0010575=PMID:16452172, GO:0001701=GO_REF:0000019, GO:0045766=GO_REF:0000019, GO:0007186=PMID:8898085, GO:0045087=Reactome:REACT_6802, GO:0033602=GO_REF:0000019, GO:0007166=PMID:10820279} P01031 Complement C5 protein 20100104 {GO:0004866=IEA, GO:0005615=IEA, GO:0010760=IDA, GO:0006957=IEA, GO:0006956=TAS, GO:0000187=TAS, GO:0006954=TAS, GO:0050921=IEA, GO:0006935=IEA, GO:0005579=IEA, GO:0019835=IEA, GO:0006958=IEA, GO:0090197=IDA, GO:0008009=TAS, GO:0002523=IEA, GO:0006874=IEA, GO:0005102=TAS, GO:0006950=TAS, GO:0005576=TAS, GO:0006917=IEA, GO:0042593=IEA, GO:0031714=IEA, GO:0010700=IEA, GO:0010575=IDA, GO:0001701=IEA, GO:0045766=IEA, GO:0007186=TAS, GO:0045087=TAS, GO:0033602=IEA, GO:0007166=TAS} G-protein coupled receptor signaling pathway, activation of MAPK activity, cell surface receptor signaling pathway, cellular calcium ion homeostasis, chemotaxis, complement activation, complement activation, alternative pathway, complement activation, classical pathway, cytolysis, glucose homeostasis, in utero embryonic development, induction of apoptosis, inflammatory response, innate immune response, leukocyte migration involved in inflammatory response, negative regulation of dopamine secretion, negative regulation of macrophage chemotaxis, negative regulation of norepinephrine secretion, positive regulation of angiogenesis, positive regulation of chemokine secretion, positive regulation of chemotaxis, positive regulation vascular endothelial growth factor production, response to stress extracellular region, extracellular space, membrane attack complex C5a anaphylatoxin chemotactic receptor binding, chemokine activity, endopeptidase inhibitor activity, receptor binding Human C5AR1 GOC UniProtKB {GO:0021534=GO_REF:0000019, GO:0005886=Reactome:REACT_22289, GO:0004944=PMID:22496247, GO:0050830=GO_REF:0000019, GO:0007606=PMID:9590258, GO:0031100=GO_REF:0000019, GO:0001856=GO_REF:0000019, GO:0007202=PMID:7649993, GO:0007204=GO_REF:0000019, GO:0038178=PMID:22496247, GO:0016323=PMID:22960554, GO:0000187=PMID:7649993, GO:0043524=GO_REF:0000019, GO:0006955=PMID:9590258, GO:0006954=GO_REF:0000019, GO:0006935=PMID:10352266, GO:0032496=GO_REF:0000019, GO:0042789=PMID:22496247, GO:0070374=PMID:22496247, GO:0004878=PMID:22496247, GO:0050679=PMID:22496247, GO:0009986=GO_REF:0000019, GO:0030593=GO_REF:0000019, GO:0006915=GO_REF:0000019, GO:0045177=PMID:22496247, GO:0004982=GO_REF:0000002, GO:0007165=PMID:8702752, GO:0006968=PMID:8779720, GO:0005887=PMID:2007135, GO:0032494=GO_REF:0000019} P21730 C5a anaphylatoxin chemotactic receptor protein 20130413 {GO:0021534=IEA, GO:0005886=TAS, GO:0004944=IDA, GO:0050830=IEA, GO:0007606=TAS, GO:0031100=IEA, GO:0001856=IEA, GO:0007202=TAS, GO:0007204=IEA, GO:0038178=IDA, GO:0016323=IDA, GO:0000187=TAS, GO:0043524=IEA, GO:0006955=TAS, GO:0006954=IEA, GO:0006935=TAS, GO:0032496=IEA, GO:0042789=IDA, GO:0070374=IDA, GO:0004878=IDA, GO:0050679=IDA, GO:0009986=IEA, GO:0030593=IEA, GO:0006915=IEA, GO:0045177=IDA, GO:0004982=IEA, GO:0007165=TAS, GO:0006968=TAS, GO:0005887=TAS, GO:0032494=IEA} activation of MAPK activity, activation of phospholipase C activity, apoptotic process, cell proliferation in hindbrain, cellular defense response, chemotaxis, complement component C5a signaling pathway, defense response to Gram-positive bacterium, elevation of cytosolic calcium ion concentration, immune response, inflammatory response, mRNA transcription from RNA polymerase II promoter, negative regulation of neuron apoptotic process, neutrophil chemotaxis, organ regeneration, positive regulation of ERK1 and ERK2 cascade, positive regulation of epithelial cell proliferation, response to lipopolysaccharide, response to peptidoglycan, sensory perception of chemical stimulus, signal transduction apical part of cell, basolateral plasma membrane, cell surface, integral to plasma membrane, plasma membrane C5a anaphylatoxin receptor activity, N-formyl peptide receptor activity, complement component C5a binding, complement component C5a receptor activity Human C5orf15 null null {} null null null null {} null null null C5orf17 null null {} null null null null {} null null null C5orf22 null null {} null null null null {} null null null C5orf24 null null {} null null null null {} null null null C5orf28 UniProtKB UniProtKB {GO:0016021=GO_REF:0000037} Q0VDI3 Transmembrane protein C5orf28 protein 20130413 {GO:0016021=IEA} integral to membrane Human UniProtKB-KW:KW-0812 C5orf30 UniProtKB UniProtKB {GO:0005515=PMID:22085962, GO:0005737=PMID:22085962, GO:0060271=GO_REF:0000024, GO:0035869=PMID:22085962, GO:0015031=GO_REF:0000037} Q96GV9 UNC119-binding protein C5orf30 protein 20120113 {GO:0005515=IPI, GO:0005737=IDA, GO:0060271=ISS, GO:0035869=IDA, GO:0015031=IEA} cilium morphogenesis, protein transport ciliary transition zone, cytoplasm protein binding Human UniProtKB:Q13432 C5orf34 null null {} null null null null {} null null null C5orf42 UniProtKB UniProtKB {GO:0016021=GO_REF:0000037} Q9H799 Uncharacterized protein C5orf42 protein 20130413 {GO:0016021=IEA} integral to membrane Human UniProtKB-KW:KW-0812 C5orf51 null null {} null null null null {} null null null C5orf54 ENSEMBL UniProtKB {GO:0005739=GO_REF:0000019} Q8IZ13 Transposon-derived Buster3 transposase-like protein protein 20130413 {GO:0005739=IEA} mitochondrion Human Ensembl:ENSMUSP00000044533 C5orf55 UniProtKB UniProtKB {GO:0005576=GO_REF:0000039} Q8N2X6 Uncharacterized protein C5orf55 protein 20130413 {GO:0005576=IEA} extracellular region Human UniProtKB-SubCell:SL-0243 C6 IntAct UniProtKB {GO:0005515=PMID:17474147, GO:0006956=PMID:2808363, GO:0005579=GO_REF:0000037, GO:0045087=Reactome:REACT_6802, GO:0019835=GO_REF:0000037, GO:0006958=GO_REF:0000037, GO:0005576=Reactome:REACT_7988, GO:0001970=GO_REF:0000019, GO:0001701=GO_REF:0000019, GO:0045766=GO_REF:0000019} P13671 Complement component C6 protein 20130415 {GO:0005515=IPI, GO:0006956=TAS, GO:0005579=IEA, GO:0045087=TAS, GO:0019835=IEA, GO:0006958=IEA, GO:0005576=TAS, GO:0001970=IEA, GO:0001701=IEA, GO:0045766=IEA} complement activation, complement activation, classical pathway, cytolysis, in utero embryonic development, innate immune response, positive regulation of activation of membrane attack complex, positive regulation of angiogenesis extracellular region, membrane attack complex protein binding Human UniProtKB:P16333 C6orf10 UniProtKB UniProtKB {GO:0016021=GO_REF:0000037} Q5SRN2 Uncharacterized protein C6orf10 protein 20130413 {GO:0016021=IEA} integral to membrane Human UniProtKB-KW:KW-0812 C6orf106 BHF-UCL UniProtKB {GO:0008150=GO_REF:0000015, GO:0003674=GO_REF:0000015, GO:0005575=GO_REF:0000015} Q9H6K1 Uncharacterized protein C6orf106 protein 20110401 {GO:0008150=ND, GO:0003674=ND, GO:0005575=ND} biological_process cellular_component molecular_function Human C6orf118 null null {} null null null null {} null null null C6orf136 ENSEMBL UniProtKB {GO:0005739=GO_REF:0000019} Q0P5T2 Uncharacterized protein C6orf136 protein 20130413 {GO:0005739=IEA} mitochondrion Human Ensembl:ENSMUSP00000116278 C6orf15 UniProtKB UniProtKB {GO:0003674=GO_REF:0000015, GO:0008150=GO_REF:0000015, GO:0005540=GO_REF:0000019, GO:0030198=GO_REF:0000019, GO:0043236=GO_REF:0000019, GO:0005575=GO_REF:0000015, GO:0005614=GO_REF:0000019, GO:0001968=GO_REF:0000019, GO:0008201=GO_REF:0000019, GO:0070052=GO_REF:0000019} Q6UXA7 Uncharacterized protein C6orf15 protein 20061107 {GO:0003674=ND, GO:0008150=ND, GO:0005540=IEA, GO:0030198=IEA, GO:0043236=IEA, GO:0005575=ND, GO:0005614=IEA, GO:0001968=IEA, GO:0008201=IEA, GO:0070052=IEA} biological_process, extracellular matrix organization cellular_component, interstitial matrix collagen V binding, fibronectin binding, heparin binding, hyaluronic acid binding, laminin binding, molecular_function Human C6orf165 null null {} null null null null {} null null null C6orf170 null null {} null null null null {} null null null C6orf201 null null {} null null null null {} null null null C6orf203 ENSEMBL UniProtKB {GO:0005739=GO_REF:0000019} J3KQ88 Uncharacterized protein C6orf203 protein 20130413 {GO:0005739=IEA} mitochondrion Human Ensembl:ENSMUSP00000019932 C6orf211 null null {} null null null null {} null null null C6orf25 null null {} null null null null {} null null null C6orf47 null null {} null null null null {} null null null C6orf62 LIFEdb UniProtKB {GO:0005622=GO_REF:0000054, GO:0003674=GO_REF:0000015, GO:0008150=GO_REF:0000015} Q9GZU0 Uncharacterized protein C6orf62 protein 20100607 {GO:0005622=IDA, GO:0003674=ND, GO:0008150=ND} biological_process intracellular molecular_function Human C6orf89 UniProtKB UniProtKB {GO:0005737=PMID:21857995, GO:0005886=PMID:21857995, GO:0000139=GO_REF:0000039, GO:0042060=PMID:21857995, GO:0005730=GO_REF:0000039, GO:0030496=GO_REF:0000039, GO:0016021=GO_REF:0000037, GO:0045787=PMID:21857995, GO:0050673=PMID:21857995} Q6UWU4 Bombesin receptor-activated protein C6orf89 protein 20110831 {GO:0005737=IDA, GO:0005886=IDA, GO:0000139=IEA, GO:0042060=IDA, GO:0005730=IEA, GO:0030496=IEA, GO:0016021=IEA, GO:0045787=IDA, GO:0050673=IDA} epithelial cell proliferation, positive regulation of cell cycle, wound healing Golgi membrane, cytoplasm, integral to membrane, midbody, nucleolus, plasma membrane Human C7 Reactome UniProtKB {GO:0006957=GO_REF:0000037, GO:0006956=PMID:3335508, GO:0005579=GO_REF:0000037, GO:0045087=Reactome:REACT_6802, GO:0019835=GO_REF:0000037, GO:0006958=GO_REF:0000037, GO:0005576=Reactome:REACT_7988} P10643 Complement component C7 protein 20060216 {GO:0006957=IEA, GO:0006956=TAS, GO:0005579=IEA, GO:0045087=TAS, GO:0019835=IEA, GO:0006958=IEA, GO:0005576=TAS} complement activation, complement activation, alternative pathway, complement activation, classical pathway, cytolysis, innate immune response extracellular region, membrane attack complex Human C7orf25 null null {} null null null null {} null null null C7orf26 null null {} null null null null {} null null null C7orf29 null null {} null null null null {} null null null C7orf31 null null {} null null null null {} null null null C7orf34 UniProtKB UniProtKB {GO:0005576=GO_REF:0000039} Q96L11 Uncharacterized protein C7orf34 protein 20130413 {GO:0005576=IEA} extracellular region Human UniProtKB-SubCell:SL-0243 C7orf41 null null {} null null null null {} null null null C7orf43 null null {} null null null null {} null null null C7orf50 null null {} null null null null {} null null null C7orf55 ENSEMBL UniProtKB {GO:0005739=GO_REF:0000019} Q96HJ9 UPF0562 protein C7orf55 protein 20130413 {GO:0005739=IEA} mitochondrion Human Ensembl:ENSMUSP00000019833 C8A Reactome UniProtKB {GO:0006957=GO_REF:0000037, GO:0006956=PMID:12413696, GO:0006955=PMID:6771072, GO:0005579=PMID:12413696, GO:0016020=PMID:2820471, GO:0045087=Reactome:REACT_6802, GO:0019835=GO_REF:0000037, GO:0006958=GO_REF:0000037, GO:0005576=Reactome:REACT_7988, GO:0005615=PMID:6771072} P07357 Complement component C8 alpha chain protein 20060216 {GO:0006957=IEA, GO:0006956=IDA, GO:0006955=TAS, GO:0005579=IDA, GO:0016020=TAS, GO:0045087=TAS, GO:0019835=IEA, GO:0006958=IEA, GO:0005576=TAS, GO:0005615=TAS} complement activation, complement activation, alternative pathway, complement activation, classical pathway, cytolysis, immune response, innate immune response extracellular region, extracellular space, membrane, membrane attack complex Human C8B Reactome UniProtKB {GO:0006957=GO_REF:0000037, GO:0006956=PMID:8098723, GO:0006955=PMID:8098723, GO:0016020=PMID:2820472, GO:0005579=GO_REF:0000037, GO:0045087=Reactome:REACT_6802, GO:0006958=GO_REF:0000037, GO:0019835=GO_REF:0000019, GO:0005576=Reactome:REACT_7988, GO:0032403=GO_REF:0000019, GO:0005615=GO_REF:0000019} P07358 Complement component C8 beta chain protein 20060216 {GO:0006957=IEA, GO:0006956=TAS, GO:0006955=TAS, GO:0016020=TAS, GO:0005579=IEA, GO:0045087=TAS, GO:0006958=IEA, GO:0019835=IEA, GO:0005576=TAS, GO:0032403=IEA, GO:0005615=IEA} complement activation, complement activation, alternative pathway, complement activation, classical pathway, cytolysis, immune response, innate immune response extracellular region, extracellular space, membrane, membrane attack complex protein complex binding Human C8G UniProtKB UniProtKB {GO:0006957=GO_REF:0000037, GO:0001848=GO_REF:0000019, GO:0005579=GO_REF:0000037, GO:0045087=Reactome:REACT_6802, GO:0019835=GO_REF:0000019, GO:0006958=GO_REF:0000037, GO:0005576=GO_REF:0000038, GO:0032403=GO_REF:0000019, GO:0005615=GO_REF:0000019, GO:0019841=GO_REF:0000037} Q5SQ08 Complement component C8 gamma chain protein 20130413 {GO:0006957=IEA, GO:0001848=IEA, GO:0005579=IEA, GO:0045087=TAS, GO:0019835=IEA, GO:0006958=IEA, GO:0005576=IEA, GO:0032403=IEA, GO:0005615=IEA, GO:0019841=IEA} complement activation, alternative pathway, complement activation, classical pathway, cytolysis, innate immune response extracellular region, extracellular space, membrane attack complex complement binding, protein complex binding, retinol binding Human UniProtKB-KW:KW-0964 C8orf33 null null {} null null null null {} null null null C8orf34 InterPro UniProtKB {GO:0007165=GO_REF:0000002, GO:0008603=GO_REF:0000002} Q49A92 Uncharacterized protein C8orf34 protein 20130413 {GO:0007165=IEA, GO:0008603=IEA} signal transduction cAMP-dependent protein kinase regulator activity Human InterPro:IPR003117 C8orf4 UniProtKB UniProtKB {GO:0006915=GO_REF:0000037} Q9NR00 Uncharacterized protein C8orf4 protein 20130413 {GO:0006915=IEA} apoptotic process Human UniProtKB-KW:KW-0053 C8orf47 null null {} null null null null {} null null null C8orf48 IntAct UniProtKB {GO:0005515=PMID:19060904} Q96LL4 Uncharacterized protein C8orf48 protein 20130415 {GO:0005515=IPI} protein binding Human UniProtKB:Q99750 C8orf59 null null {} null null null null {} null null null C8orf76 null null {} null null null null {} null null null C9 HPA UniProtKB {GO:0006957=GO_REF:0000037, GO:0005737=GO_REF:0000052, GO:0005886=GO_REF:0000052, GO:0005579=GO_REF:0000037, GO:0005887=PMID:2426252, GO:0045087=Reactome:REACT_6802, GO:0019836=PMID:2426252, GO:0019835=GO_REF:0000037, GO:0006958=GO_REF:0000037, GO:0005576=Reactome:REACT_7988} P02748 Complement component C9 protein 20120912 {GO:0006957=IEA, GO:0005737=IDA, GO:0005886=IDA, GO:0005579=IEA, GO:0005887=TAS, GO:0045087=TAS, GO:0019836=TAS, GO:0019835=IEA, GO:0006958=IEA, GO:0005576=TAS} complement activation, alternative pathway, complement activation, classical pathway, cytolysis, hemolysis by symbiont of host erythrocytes, innate immune response cytoplasm, extracellular region, integral to plasma membrane, membrane attack complex, plasma membrane Human C9orf106 null null {} null null null null {} null null null C9orf114 UniProtKB UniProtKB {GO:0008150=GO_REF:0000015, GO:0003674=GO_REF:0000015, GO:0005575=GO_REF:0000015} Q5T280 Uncharacterized protein C9orf114 protein 20081126 {GO:0008150=ND, GO:0003674=ND, GO:0005575=ND} biological_process cellular_component molecular_function Human C9orf117 null null {} null null null null {} null null null C9orf123 UniProtKB UniProtKB {GO:0016021=GO_REF:0000037} Q96GE9 Transmembrane protein C9orf123 protein 20130413 {GO:0016021=IEA} integral to membrane Human UniProtKB-KW:KW-0812 C9orf142 null null {} null null null null {} null null null C9orf156 UniProtKB UniProtKB {GO:0016787=GO_REF:0000037, GO:0019048=GO_REF:0000037} Q9BU70 Nef-associated protein 1 protein 20130413 {GO:0016787=IEA, GO:0019048=IEA} virus-host interaction hydrolase activity Human UniProtKB-KW:KW-0945 C9orf16 UniProtKB UniProtKB {GO:0003674=GO_REF:0000015, GO:0008150=GO_REF:0000015, GO:0005575=GO_REF:0000015} Q9BUW7 UPF0184 protein C9orf16 protein 20061026 {GO:0003674=ND, GO:0008150=ND, GO:0005575=ND} biological_process cellular_component molecular_function Human C9orf163 null null {} null null null null {} null null null C9orf169 null null {} null null null null {} null null null C9orf24 null null {} null null null null {} null null null C9orf3 InterPro UniProtKB {GO:0019370=GO_REF:0000002, GO:0004177=GO_REF:0000038, GO:0006508=GO_REF:0000002, GO:0008270=GO_REF:0000002, GO:0008237=GO_REF:0000002} H0YCM2 Protein C9orf3 protein 20130413 {GO:0019370=IEA, GO:0004177=IEA, GO:0006508=IEA, GO:0008270=IEA, GO:0008237=IEA} leukotriene biosynthetic process, proteolysis aminopeptidase activity, metallopeptidase activity, zinc ion binding Human InterPro:IPR015211 C9orf40 null null {} null null null null {} null null null C9orf41 null null {} null null null null {} null null null C9orf43 null null {} null null null null {} null null null C9orf50 null null {} null null null null {} null null null C9orf64 UniProtKB UniProtKB {GO:0008150=GO_REF:0000015, GO:0003674=GO_REF:0000015, GO:0005575=GO_REF:0000015} Q5T6V5 UPF0553 protein C9orf64 protein 20080604 {GO:0008150=ND, GO:0003674=ND, GO:0005575=ND} biological_process cellular_component molecular_function Human C9orf72 UniProtKB UniProtKB {GO:0008219=GO_REF:0000037, GO:0005737=GO_REF:0000039, GO:0005634=GO_REF:0000039} Q96LT7 Protein C9orf72 protein 20130413 {GO:0008219=IEA, GO:0005737=IEA, GO:0005634=IEA} cell death cytoplasm, nucleus Human UniProtKB-SubCell:SL-0086 C9orf78 HPA UniProtKB {GO:0005737=GO_REF:0000052, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052} Q9NZ63 Uncharacterized protein C9orf78 protein 20100326 {GO:0005737=IDA, GO:0005730=IDA, GO:0005634=IDA} cytoplasm, nucleolus, nucleus Human C9orf89 UniProtKB UniProtKB {GO:0050700=PMID:15637807, GO:0005634=PMID:15637807, GO:0043124=PMID:15637807, GO:0005829=PMID:15637807} Q96LW7 Bcl10-interacting CARD protein protein 20050818 {GO:0050700=NAS, GO:0005634=NAS, GO:0043124=NAS, GO:0005829=NAS} negative regulation of I-kappaB kinase/NF-kappaB cascade cytosol, nucleus CARD domain binding Human C9orf9 UniProtKB UniProtKB {GO:0005881=PMID:23264731} Q96E40 Uncharacterized protein C9orf9 protein 20130311 {GO:0005881=IDA} cytoplasmic microtubule Human C9orf91 UniProtKB UniProtKB {GO:0016021=GO_REF:0000037} Q5VZI3 Transmembrane protein C9orf91 protein 20130413 {GO:0016021=IEA} integral to membrane Human UniProtKB-KW:KW-0812 CA1 HPA UniProtKB {GO:0005737=GO_REF:0000052, GO:0005794=GO_REF:0000052, GO:0015701=Reactome:REACT_121380, GO:0008270=GO_REF:0000002, GO:0044281=Reactome:REACT_111217, GO:0004089=GO_REF:0000003, GO:0006730=GO_REF:0000002, GO:0005829=Reactome:REACT_121371} P00915 Carbonic anhydrase 1 protein 20080818 {GO:0005737=IDA, GO:0005794=IDA, GO:0015701=TAS, GO:0008270=IEA, GO:0044281=TAS, GO:0004089=IEA, GO:0006730=IEA, GO:0005829=TAS} bicarbonate transport, one-carbon metabolic process, small molecule metabolic process Golgi apparatus, cytoplasm, cytosol carbonate dehydratase activity, zinc ion binding Human CA11 UniProtKB UniProtKB {GO:0016323=GO_REF:0000019, GO:0005576=GO_REF:0000039, GO:0004089=PMID:9878252} O75493 Carbonic anhydrase-related protein 11 protein 20081212 {GO:0016323=IEA, GO:0005576=IEA, GO:0004089=TAS} basolateral plasma membrane, extracellular region carbonate dehydratase activity NOT Human CA12 Reactome UniProtKB {GO:0005886=Reactome:REACT_121310, GO:0015701=Reactome:REACT_121123, GO:0008270=GO_REF:0000002, GO:0044281=Reactome:REACT_111217, GO:0016021=GO_REF:0000037, GO:0004089=GO_REF:0000003, GO:0006730=GO_REF:0000002} O43570 Carbonic anhydrase 12 protein 20110807 {GO:0005886=TAS, GO:0015701=TAS, GO:0008270=IEA, GO:0044281=TAS, GO:0016021=IEA, GO:0004089=IEA, GO:0006730=IEA} bicarbonate transport, one-carbon metabolic process, small molecule metabolic process integral to membrane, plasma membrane carbonate dehydratase activity, zinc ion binding Human CA14 Reactome UniProtKB {GO:0005886=Reactome:REACT_121310, GO:0015701=Reactome:REACT_121123, GO:0044281=Reactome:REACT_111217, GO:0016021=GO_REF:0000037, GO:0004089=GO_REF:0000003, GO:0046872=GO_REF:0000037} Q9ULX7 Carbonic anhydrase 14 protein 20110807 {GO:0005886=TAS, GO:0015701=TAS, GO:0044281=TAS, GO:0016021=IEA, GO:0004089=IEA, GO:0046872=IEA} bicarbonate transport, small molecule metabolic process integral to membrane, plasma membrane carbonate dehydratase activity, metal ion binding Human CA2 HPA UniProtKB {GO:0030424=GO_REF:0000019, GO:0043627=GO_REF:0000019, GO:0001822=GO_REF:0000019, GO:0006950=GO_REF:0000019, GO:0045177=PMID:14675051, GO:0045672=GO_REF:0000019, GO:0032849=GO_REF:0000019, GO:0044281=Reactome:REACT_111217, GO:0004089=GO_REF:0000003, GO:0015670=GO_REF:0000019, GO:0005615=GO_REF:0000019, GO:0010043=GO_REF:0000019, GO:0046903=GO_REF:0000019, GO:0005829=Reactome:REACT_121371, GO:0005902=GO_REF:0000019, GO:0016323=GO_REF:0000019, GO:0005737=GO_REF:0000052, GO:0045780=GO_REF:0000019, GO:0015701=Reactome:REACT_121380, GO:0042475=GO_REF:0000019, GO:0008270=PMID:3151020, GO:0006730=GO_REF:0000002, GO:0002009=GO_REF:0000019, GO:0009268=GO_REF:0000019} P00918 Carbonic anhydrase 2 protein 20101115 {GO:0030424=IEA, GO:0043627=IEA, GO:0001822=IEA, GO:0006950=IEA, GO:0045177=IDA, GO:0045672=IEA, GO:0032849=IEA, GO:0044281=TAS, GO:0004089=IEA, GO:0015670=IEA, GO:0005615=IEA, GO:0010043=IEA, GO:0046903=IEA, GO:0005829=TAS, GO:0005902=IEA, GO:0016323=IEA, GO:0005737=IDA, GO:0045780=IEA, GO:0015701=TAS, GO:0042475=IEA, GO:0008270=IDA, GO:0006730=IEA, GO:0002009=IEA, GO:0009268=IEA} bicarbonate transport, carbon dioxide transport, kidney development, morphogenesis of an epithelium, odontogenesis of dentin-containing tooth, one-carbon metabolic process, positive regulation of bone resorption, positive regulation of cellular pH reduction, positive regulation of osteoclast differentiation, response to estrogen stimulus, response to pH, response to stress, response to zinc ion, secretion, small molecule metabolic process apical part of cell, axon, basolateral plasma membrane, cytoplasm, cytosol, extracellular space, microvillus carbonate dehydratase activity, zinc ion binding Human CA3 Reactome UniProtKB {GO:0015701=Reactome:REACT_121123, GO:0008270=GO_REF:0000002, GO:0044281=Reactome:REACT_111217, GO:0004089=GO_REF:0000003, GO:0006730=GO_REF:0000002, GO:0006979=GO_REF:0000019, GO:0005829=Reactome:REACT_120951, GO:0016151=GO_REF:0000019} P07451 Carbonic anhydrase 3 protein 20110807 {GO:0015701=TAS, GO:0008270=IEA, GO:0044281=TAS, GO:0004089=IEA, GO:0006730=IEA, GO:0006979=IEA, GO:0005829=TAS, GO:0016151=IEA} bicarbonate transport, one-carbon metabolic process, response to oxidative stress, small molecule metabolic process cytosol carbonate dehydratase activity, nickel cation binding, zinc ion binding Human CA4 Reactome UniProtKB {GO:0005515=PMID:15563508, GO:0005802=PMID:17409381, GO:0048471=PMID:17409381, GO:0005886=Reactome:REACT_121310, GO:0044281=Reactome:REACT_111217, GO:0048513=GO_REF:0000019, GO:0031225=GO_REF:0000002, GO:0031526=PMID:17409381, GO:0031362=PMID:17409381, GO:0016323=PMID:17409381, GO:0016324=PMID:17409381, GO:0044459=PMID:15563508, GO:0006730=GO_REF:0000002, GO:0030658=PMID:17409381, GO:0005791=PMID:17409381, GO:0005793=PMID:17409381, GO:0005794=PMID:17409381, GO:0009986=PMID:15563508, GO:0042493=GO_REF:0000019, GO:0004089=Reactome:REACT_120877, GO:0048545=GO_REF:0000019, GO:0042383=GO_REF:0000019, GO:0016529=GO_REF:0000019, GO:0016020=PMID:6811592, GO:0015701=Reactome:REACT_121380, GO:0008270=GO_REF:0000002, GO:0030667=PMID:17409381} P22748 Carbonic anhydrase 4 protein 20110807 {GO:0005515=IPI, GO:0005802=IDA, GO:0048471=IDA, GO:0005886=TAS, GO:0044281=TAS, GO:0048513=IEA, GO:0031225=IEA, GO:0031526=IDA, GO:0031362=IDA, GO:0016323=IDA, GO:0016324=IDA, GO:0044459=IDA, GO:0006730=IEA, GO:0030658=IDA, GO:0005791=IDA, GO:0005793=IDA, GO:0005794=IDA, GO:0009986=IDA, GO:0042493=IEA, GO:0004089=TAS, GO:0048545=IEA, GO:0042383=IEA, GO:0016529=IEA, GO:0016020=TAS, GO:0015701=TAS, GO:0008270=IEA, GO:0030667=IDA} bicarbonate transport, one-carbon metabolic process, organ development, response to drug, response to steroid hormone stimulus, small molecule metabolic process Golgi apparatus, anchored to external side of plasma membrane, anchored to membrane, apical plasma membrane, basolateral plasma membrane, brush border membrane, cell surface, endoplasmic reticulum-Golgi intermediate compartment, membrane, perinuclear region of cytoplasm, plasma membrane, plasma membrane part, rough endoplasmic reticulum, sarcolemma, sarcoplasmic reticulum, secretory granule membrane, trans-Golgi network, transport vesicle membrane carbonate dehydratase activity, protein binding, zinc ion binding Human CA5A Reactome UniProtKB {GO:0005739=PMID:8356065, GO:0005759=Reactome:REACT_120942, GO:0015701=Reactome:REACT_121123, GO:0008270=GO_REF:0000002, GO:0044281=Reactome:REACT_111217, GO:0004089=GO_REF:0000003, GO:0006730=GO_REF:0000002} P35218 Carbonic anhydrase 5A, mitochondrial protein 20110807 {GO:0005739=TAS, GO:0005759=TAS, GO:0015701=TAS, GO:0008270=IEA, GO:0044281=TAS, GO:0004089=IEA, GO:0006730=IEA} bicarbonate transport, one-carbon metabolic process, small molecule metabolic process mitochondrial matrix, mitochondrion carbonate dehydratase activity, zinc ion binding Human CA5B Reactome UniProtKB {GO:0005739=PMID:10409679, GO:0005759=Reactome:REACT_120942, GO:0015701=Reactome:REACT_121123, GO:0008270=GO_REF:0000002, GO:0044281=Reactome:REACT_111217, GO:0004089=GO_REF:0000003, GO:0006730=GO_REF:0000002} Q9Y2D0 Carbonic anhydrase 5B, mitochondrial protein 20110807 {GO:0005739=TAS, GO:0005759=TAS, GO:0015701=TAS, GO:0008270=IEA, GO:0044281=TAS, GO:0004089=IEA, GO:0006730=IEA} bicarbonate transport, one-carbon metabolic process, small molecule metabolic process mitochondrial matrix, mitochondrion carbonate dehydratase activity, zinc ion binding Human CA6 Reactome UniProtKB {GO:0005737=GO_REF:0000019, GO:0015701=Reactome:REACT_121123, GO:0005576=Reactome:REACT_120867, GO:0008270=GO_REF:0000002, GO:0044281=Reactome:REACT_111217, GO:0004089=Reactome:REACT_120867, GO:0005615=GO_REF:0000019, GO:0006730=GO_REF:0000002} P23280 Carbonic anhydrase 6 protein 20110807 {GO:0005737=IEA, GO:0015701=TAS, GO:0005576=TAS, GO:0008270=IEA, GO:0044281=TAS, GO:0004089=TAS, GO:0005615=IEA, GO:0006730=IEA} bicarbonate transport, one-carbon metabolic process, small molecule metabolic process cytoplasm, extracellular region, extracellular space carbonate dehydratase activity, zinc ion binding Human CA8 ENSEMBL UniProtKB {GO:0005737=GO_REF:0000019, GO:0048015=GO_REF:0000019, GO:0008270=GO_REF:0000002, GO:0004089=GO_REF:0000002, GO:0006730=GO_REF:0000002} P35219 Carbonic anhydrase-related protein protein 20130413 {GO:0005737=IEA, GO:0048015=IEA, GO:0008270=IEA, GO:0004089=IEA, GO:0006730=IEA} one-carbon metabolic process, phosphatidylinositol-mediated signaling cytoplasm carbonate dehydratase activity, zinc ion binding Human Ensembl:ENSMUSP00000063511 CA9 Reactome UniProtKB {GO:0005886=Reactome:REACT_121310, GO:0005730=GO_REF:0000039, GO:0071456=Reactome:REACT_121311, GO:0031528=GO_REF:0000039, GO:0061418=Reactome:REACT_120815, GO:0033554=Reactome:REACT_120956, GO:0004089=GO_REF:0000003, GO:0044281=Reactome:REACT_111217, GO:0046903=GO_REF:0000019, GO:0015701=Reactome:REACT_121123, GO:0008270=GO_REF:0000002, GO:0016021=GO_REF:0000037, GO:0006730=GO_REF:0000002, GO:0002009=GO_REF:0000019} Q16790 Carbonic anhydrase 9 protein 20130301 {GO:0005886=TAS, GO:0005730=IEA, GO:0071456=TAS, GO:0031528=IEA, GO:0061418=TAS, GO:0033554=TAS, GO:0004089=IEA, GO:0044281=TAS, GO:0046903=IEA, GO:0015701=TAS, GO:0008270=IEA, GO:0016021=IEA, GO:0006730=IEA, GO:0002009=IEA} bicarbonate transport, cellular response to hypoxia, cellular response to stress, morphogenesis of an epithelium, one-carbon metabolic process, regulation of transcription from RNA polymerase II promoter in response to hypoxia, secretion, small molecule metabolic process integral to membrane, microvillus membrane, nucleolus, plasma membrane carbonate dehydratase activity, zinc ion binding Human CAB39 GOC UniProtKB {GO:0008286=Reactome:REACT_498, GO:0005515=PMID:20562859, GO:0004674=PMID:19892943, GO:0045860=PMID:19892943, GO:0007050=Reactome:REACT_21387, GO:0030295=PMID:19892943, GO:0019900=PMID:19892943, GO:0005829=Reactome:REACT_21345} Q9Y376 Calcium-binding protein 39 protein 20130413 {GO:0008286=TAS, GO:0005515=IPI, GO:0004674=IDA, GO:0045860=IDA, GO:0007050=TAS, GO:0030295=IDA, GO:0019900=IPI, GO:0005829=TAS} cell cycle arrest, insulin receptor signaling pathway, positive regulation of protein kinase activity cytosol kinase binding, protein binding, protein kinase activator activity, protein serine/threonine kinase activity Human CAB39L Reactome UniProtKB {GO:0008286=Reactome:REACT_498, GO:0007050=Reactome:REACT_21387, GO:0005829=Reactome:REACT_21345} Q9H9S4 Calcium-binding protein 39-like protein 20130301 {GO:0008286=TAS, GO:0007050=TAS, GO:0005829=TAS} cell cycle arrest, insulin receptor signaling pathway cytosol Human CABIN1 HPA UniProtKB {GO:0005737=GO_REF:0000052, GO:0016235=GO_REF:0000052, GO:0004864=PMID:9655484, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0007166=PMID:9655484, GO:0016568=GO_REF:0000037} Q9Y6J0 Calcineurin-binding protein cabin-1 protein 20111111 {GO:0005737=IDA, GO:0016235=IDA, GO:0004864=NAS, GO:0005730=IDA, GO:0005634=IDA, GO:0007166=NAS, GO:0016568=IEA} cell surface receptor signaling pathway, chromatin modification aggresome, cytoplasm, nucleolus, nucleus protein phosphatase inhibitor activity Human CABLES1 Reactome UniProtKB {GO:0007049=GO_REF:0000037, GO:0007596=Reactome:REACT_604, GO:0051726=GO_REF:0000002, GO:0005634=GO_REF:0000039, GO:0016538=GO_REF:0000002, GO:0051302=GO_REF:0000002, GO:0005829=PMID:17101133, GO:0007399=GO_REF:0000019, GO:0051301=GO_REF:0000037} Q8TDN4 CDK5 and ABL1 enzyme substrate 1 protein 20101112 {GO:0007049=IEA, GO:0007596=TAS, GO:0051726=IEA, GO:0005634=IEA, GO:0016538=IEA, GO:0051302=IEA, GO:0005829=IDA, GO:0007399=IEA, GO:0051301=IEA} blood coagulation, cell cycle, cell division, nervous system development, regulation of cell cycle, regulation of cell division cytosol, nucleus cyclin-dependent protein serine/threonine kinase regulator activity Human CABLES2 UniProtKB UniProtKB {GO:0007049=GO_REF:0000037, GO:0051726=GO_REF:0000002, GO:0016538=GO_REF:0000002, GO:0051302=GO_REF:0000002, GO:0051301=GO_REF:0000037} Q9BTV7 CDK5 and ABL1 enzyme substrate 2 protein 20130413 {GO:0007049=IEA, GO:0051726=IEA, GO:0016538=IEA, GO:0051302=IEA, GO:0051301=IEA} cell cycle, cell division, regulation of cell cycle, regulation of cell division cyclin-dependent protein serine/threonine kinase regulator activity Human UniProtKB-KW:KW-0132 CABP1 GOC UniProtKB {GO:0005515=PMID:15140941, GO:0004857=PMID:9920909, GO:0048471=GO_REF:0000039, GO:0030054=GO_REF:0000037, GO:0005886=PMID:19338761, GO:0005509=GO_REF:0000002, GO:0014069=PMID:15140941, GO:0005634=GO_REF:0000019, GO:0043086=PMID:9920909, GO:0000139=PMID:19338761, GO:0045211=GO_REF:0000037, GO:0043025=GO_REF:0000019, GO:0042308=GO_REF:0000024, GO:0008139=GO_REF:0000024, GO:0005938=GO_REF:0000039, GO:0048306=PMID:15980432} Q9NZU7 Calcium-binding protein 1 protein 20130413 {GO:0005515=IPI, GO:0004857=TAS, GO:0048471=IEA, GO:0030054=IEA, GO:0005886=IDA, GO:0005509=IEA, GO:0014069=IDA, GO:0005634=IEA, GO:0043086=TAS, GO:0000139=IDA, GO:0045211=IEA, GO:0043025=IEA, GO:0042308=ISS, GO:0008139=ISS, GO:0005938=IEA, GO:0048306=IPI} negative regulation of catalytic activity, negative regulation of protein import into nucleus Golgi membrane, cell cortex, cell junction, neuronal cell body, nucleus, perinuclear region of cytoplasm, plasma membrane, postsynaptic density, postsynaptic membrane calcium ion binding, calcium-dependent protein binding, enzyme inhibitor activity, nuclear localization sequence binding, protein binding Human CABP2 MGI UniProtKB {GO:0007165=PMID:10625670, GO:0048471=GO_REF:0000039, GO:0005794=PMID:19338761, GO:0005886=PMID:19338761, GO:0005509=GO_REF:0000002} Q9NPB3 Calcium-binding protein 2 protein 20120319 {GO:0007165=TAS, GO:0048471=IEA, GO:0005794=IDA, GO:0005886=IDA, GO:0005509=IEA} signal transduction Golgi apparatus, perinuclear region of cytoplasm, plasma membrane calcium ion binding Human CABP4 MGI UniProtKB {GO:0007165=PMID:10625670, GO:0046549=GO_REF:0000019, GO:0060040=GO_REF:0000019, GO:0043195=PMID:15452577, GO:0005509=PMID:15452577, GO:0045202=PMID:16960802, GO:0005576=PMID:16960802, GO:0007602=GO_REF:0000019, GO:0007601=PMID:16960802, GO:0008594=GO_REF:0000019, GO:0005829=PMID:19338761} P57796 Calcium-binding protein 4 protein 20120604 {GO:0007165=NAS, GO:0046549=IEA, GO:0060040=IEA, GO:0043195=TAS, GO:0005509=TAS, GO:0045202=TAS, GO:0005576=NAS, GO:0007602=IEA, GO:0007601=IMP, GO:0008594=IEA, GO:0005829=IDA} photoreceptor cell morphogenesis, phototransduction, retinal bipolar neuron differentiation, retinal cone cell development, signal transduction, visual perception cytosol, extracellular region, synapse, terminal bouton calcium ion binding Human CABP5 HPA UniProtKB {GO:0007165=PMID:10625670, GO:0005737=GO_REF:0000052, GO:0015630=GO_REF:0000052, GO:0005509=PMID:10625670, GO:0005575=GO_REF:0000015, GO:0005829=PMID:19338761} Q9NP86 Calcium-binding protein 5 protein 20110516 {GO:0007165=NAS, GO:0005737=IDA, GO:0015630=IDA, GO:0005509=NAS, GO:0005575=ND, GO:0005829=IDA} signal transduction cellular_component, cytoplasm, cytosol, microtubule cytoskeleton calcium ion binding Human CABYR BHF-UCL UniProtKB {GO:0017124=PMID:11820818, GO:0008603=GO_REF:0000002, GO:0019901=GO_REF:0000019, GO:0046982=PMID:20731842, GO:0001539=PMID:18421703, GO:0019904=PMID:18421703, GO:0005509=PMID:11820818, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0007165=GO_REF:0000002, GO:0005737=PMID:11820818, GO:0035686=PMID:11820818, GO:0005856=GO_REF:0000039, GO:0048240=PMID:11820818} O75952 Calcium-binding tyrosine phosphorylation-regulated protein protein 20110222 {GO:0017124=NAS, GO:0008603=IEA, GO:0019901=IEA, GO:0046982=ISS, GO:0001539=IDA, GO:0019904=TAS, GO:0005509=IDA, GO:0005730=IDA, GO:0005634=IDA, GO:0007165=IEA, GO:0005737=IDA, GO:0035686=IDA, GO:0005856=IEA, GO:0048240=NAS} ciliary or flagellar motility, signal transduction, sperm capacitation cytoplasm, cytoskeleton, nucleolus, nucleus, sperm fibrous sheath SH3 domain binding, cAMP-dependent protein kinase regulator activity, calcium ion binding, protein domain specific binding, protein heterodimerization activity, protein kinase binding Human UniProtKB:Q9D424 CACHD1 UniProtKB UniProtKB {GO:0006816=GO_REF:0000037, GO:0016021=GO_REF:0000037} Q5VU97 VWFA and cache domain-containing protein 1 protein 20130413 {GO:0006816=IEA, GO:0016021=IEA} calcium ion transport integral to membrane Human UniProtKB-KW:KW-0812 CACNA1A IntAct UniProtKB {GO:0005515=PMID:21078624, GO:0019905=PMID:8692999, GO:0008219=PMID:16595610, GO:0051899=Reactome:REACT_13606, GO:0005245=PMID:12451115, GO:0005886=Reactome:REACT_16913, GO:0007268=Reactome:REACT_13685, GO:0005634=PMID:16595610, GO:0044281=Reactome:REACT_111217, GO:0042995=PMID:16595610, GO:0005891=GO_REF:0000002, GO:0007204=GO_REF:0000024, GO:0046872=GO_REF:0000037, GO:0005737=PMID:16595610, GO:0006112=Reactome:REACT_1505, GO:0050796=Reactome:REACT_18325, GO:0016021=PMID:16595610} O00555 Voltage-dependent P/Q-type calcium channel subunit alpha-1A protein 20130415 {GO:0005515=IPI, GO:0019905=IDA, GO:0008219=IDA, GO:0051899=TAS, GO:0005245=IDA, GO:0005886=TAS, GO:0007268=TAS, GO:0005634=IDA, GO:0044281=TAS, GO:0042995=IDA, GO:0005891=IEA, GO:0007204=ISS, GO:0046872=IEA, GO:0005737=IDA, GO:0006112=TAS, GO:0050796=TAS, GO:0016021=TAS} cell death, elevation of cytosolic calcium ion concentration, energy reserve metabolic process, membrane depolarization, regulation of insulin secretion, small molecule metabolic process, synaptic transmission cell projection, cytoplasm, integral to membrane, nucleus, plasma membrane, voltage-gated calcium channel complex metal ion binding, protein binding, syntaxin binding, voltage-gated calcium channel activity Human UniProtKB:Q9UHX1 CACNA1B InterPro UniProtKB {GO:0005515=PMID:20195357, GO:0051899=Reactome:REACT_13606, GO:0005886=Reactome:REACT_12594, GO:0005245=GO_REF:0000002, GO:0005509=GO_REF:0000002, GO:0008016=GO_REF:0000019, GO:0007268=Reactome:REACT_13685, GO:0008022=PMID:15728831, GO:0005891=GO_REF:0000002, GO:0005524=GO_REF:0000037, GO:0007269=GO_REF:0000019, GO:0030425=GO_REF:0000019, GO:0043025=GO_REF:0000019, GO:0051924=GO_REF:0000019, GO:0006810=PMID:1321501, GO:0008217=GO_REF:0000019, GO:0007626=GO_REF:0000019, GO:0048265=GO_REF:0000019} Q9HBH2 Calcium channel alpha12.2 subunit protein 20130413 {GO:0005515=IPI, GO:0051899=TAS, GO:0005886=TAS, GO:0005245=IEA, GO:0005509=IEA, GO:0008016=IEA, GO:0007268=TAS, GO:0008022=IPI, GO:0005891=IEA, GO:0005524=IEA, GO:0007269=IEA, GO:0030425=IEA, GO:0043025=IEA, GO:0051924=IEA, GO:0006810=TAS, GO:0008217=IEA, GO:0007626=IEA, GO:0048265=IEA} locomotory behavior, membrane depolarization, neurotransmitter secretion, regulation of blood pressure, regulation of calcium ion transport, regulation of heart contraction, response to pain, synaptic transmission, transport dendrite, neuronal cell body, plasma membrane, voltage-gated calcium channel complex ATP binding, calcium ion binding, protein C-terminus binding, protein binding, voltage-gated calcium channel activity Human InterPro:IPR005447 CACNA1C BHF-UCL UniProtKB {GO:0035585=PMID:11576544, GO:0005515=PMID:15140941, GO:0005516=PMID:15140941, GO:0030018=GO_REF:0000024, GO:0060402=PMID:19095005, GO:0005886=Reactome:REACT_16913, GO:0007268=GO_REF:0000019, GO:0044281=Reactome:REACT_111217, GO:0007204=PMID:12130699, GO:0046872=GO_REF:0000037, GO:0019229=GO_REF:0000019, GO:0005737=PMID:11206130, GO:0007411=Reactome:REACT_18266, GO:0043198=GO_REF:0000019, GO:0017156=GO_REF:0000019, GO:0043025=GO_REF:0000019, GO:0007628=GO_REF:0000019, GO:0030252=GO_REF:0000019, GO:0046620=GO_REF:0000019, GO:0005245=PMID:8392192, GO:0010881=PMID:11576544, GO:0008331=PMID:11576544, GO:0014069=PMID:14140941, GO:0042593=GO_REF:0000019, GO:0086064=PMID:11576544, GO:0005891=PMID:12130699, GO:0060083=GO_REF:0000019, GO:0002095=GO_REF:0000019, GO:0006112=Reactome:REACT_1505, GO:0050796=Reactome:REACT_18325, GO:0008542=GO_REF:0000019, GO:0008217=GO_REF:0000019, GO:0016021=PMID:8392192, GO:0030073=GO_REF:0000019} Q13936 Voltage-dependent L-type calcium channel subunit alpha-1C protein 20130213 {GO:0035585=TAS, GO:0005515=IPI, GO:0005516=IPI, GO:0030018=ISS, GO:0060402=TAS, GO:0005886=TAS, GO:0007268=IEA, GO:0044281=TAS, GO:0007204=IDA, GO:0046872=IEA, GO:0019229=IEA, GO:0005737=IDA, GO:0007411=TAS, GO:0043198=IEA, GO:0017156=IEA, GO:0043025=IEA, GO:0007628=IEA, GO:0030252=IEA, GO:0046620=IEA, GO:0005245=IDA, GO:0010881=TAS, GO:0008331=TAS, GO:0014069=IDA, GO:0042593=IEA, GO:0086064=TAS, GO:0005891=IDA, GO:0060083=IEA, GO:0002095=IEA, GO:0006112=TAS, GO:0050796=TAS, GO:0008542=IEA, GO:0008217=IEA, GO:0016021=IDA, GO:0030073=IEA} adult walking behavior, axon guidance, calcium ion transport into cytosol, calcium ion-dependent exocytosis, calcium-mediated signaling using extracellular calcium source, cell communication by electrical coupling involved in cardiac conduction, elevation of cytosolic calcium ion concentration, energy reserve metabolic process, glucose homeostasis, growth hormone secretion, insulin secretion, regulation of blood pressure, regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion, regulation of insulin secretion, regulation of organ growth, regulation of vasoconstriction, small molecule metabolic process, smooth muscle contraction involved in micturition, synaptic transmission, visual learning Z disc, caveolar macromolecular signaling complex, cytoplasm, dendritic shaft, integral to membrane, neuronal cell body, plasma membrane, postsynaptic density, voltage-gated calcium channel complex calmodulin binding, high voltage-gated calcium channel activity, metal ion binding, protein binding, voltage-gated calcium channel activity Human CACNA1D InterPro UniProtKB {GO:0086052=PMID:21131953, GO:0005245=GO_REF:0000002, GO:0005886=PMID:21859974, GO:0051928=PMID:1309651, GO:0007605=PMID:21131953, GO:0030506=PMID:21859974, GO:0044281=Reactome:REACT_111217, GO:0086091=PMID:21131953, GO:0005891=GO_REF:0000002, GO:0046872=GO_REF:0000037, GO:0070509=PMID:1309651, GO:0060372=GO_REF:0000024, GO:0006112=Reactome:REACT_1505, GO:0050796=Reactome:REACT_18325, GO:0007411=Reactome:REACT_18266, GO:0086059=PMID:21131953, GO:0007188=GO_REF:0000024, GO:0006816=PMID:11160515, GO:0086012=PMID:21859974, GO:0086007=PMID:21859974} Q59GD8 Voltage-dependent L-type calcium channel subunit alpha-1D protein 20130413 {GO:0086052=IMP, GO:0005245=IEA, GO:0005886=ISS, GO:0051928=IDA, GO:0007605=IMP, GO:0030506=ISS, GO:0044281=TAS, GO:0086091=IMP, GO:0005891=IEA, GO:0046872=IEA, GO:0070509=IDA, GO:0060372=ISS, GO:0006112=TAS, GO:0050796=TAS, GO:0007411=TAS, GO:0086059=IMP, GO:0007188=ISS, GO:0006816=IDA, GO:0086012=IC, GO:0086007=IC} adenylate cyclase-modulating G-protein coupled receptor signaling pathway, axon guidance, calcium ion import, calcium ion transport, energy reserve metabolic process, membrane depolarization involved in regulation of cardiac muscle cell action potential, membrane repolarization involved in regulation of SA node cell action potential, positive regulation of calcium ion transport, regulation of atrial cardiac muscle cell membrane repolarization, regulation of heart rate by cardiac conduction, regulation of insulin secretion, sensory perception of sound, small molecule metabolic process plasma membrane, voltage-gated calcium channel complex ankyrin binding, metal ion binding, voltage-gated calcium channel activity, voltage-gated calcium channel activity involved in regulation of SA node cell action potential, voltage-gated calcium channel activity involved in regulation of cardiac muscle cell action potential Human InterPro:IPR002077|InterPro:IPR005452 CACNA1E Reactome UniProtKB {GO:0051899=Reactome:REACT_13606, GO:0005886=Reactome:REACT_16913, GO:0005245=PMID:8071363, GO:0005509=GO_REF:0000002, GO:0007268=Reactome:REACT_13685, GO:0044281=Reactome:REACT_111217, GO:0030317=GO_REF:0000019, GO:0042593=GO_REF:0000019, GO:0090273=GO_REF:0000019, GO:0019226=GO_REF:0000019, GO:0005891=GO_REF:0000002, GO:0019233=GO_REF:0000019, GO:0006112=Reactome:REACT_1505, GO:0050796=Reactome:REACT_18325, GO:0002027=GO_REF:0000019, GO:0008542=GO_REF:0000019, GO:0006810=PMID:8071363, GO:0001662=GO_REF:0000019, GO:0007626=GO_REF:0000019, GO:0048266=GO_REF:0000019, GO:0061178=GO_REF:0000019} Q15878 Voltage-dependent R-type calcium channel subunit alpha-1E protein 20130213 {GO:0051899=TAS, GO:0005886=TAS, GO:0005245=IDA, GO:0005509=IEA, GO:0007268=TAS, GO:0044281=TAS, GO:0030317=IEA, GO:0042593=IEA, GO:0090273=IEA, GO:0019226=IEA, GO:0005891=IEA, GO:0019233=IEA, GO:0006112=TAS, GO:0050796=TAS, GO:0002027=IEA, GO:0008542=IEA, GO:0006810=TAS, GO:0001662=IEA, GO:0007626=IEA, GO:0048266=IEA, GO:0061178=IEA} behavioral fear response, behavioral response to pain, energy reserve metabolic process, glucose homeostasis, locomotory behavior, membrane depolarization, regulation of heart rate, regulation of insulin secretion, regulation of insulin secretion involved in cellular response to glucose stimulus, regulation of somatostatin secretion, sensory perception of pain, small molecule metabolic process, sperm motility, synaptic transmission, transmission of nerve impulse, transport, visual learning plasma membrane, voltage-gated calcium channel complex calcium ion binding, voltage-gated calcium channel activity Human CACNA1F UniProtKB UniProtKB {GO:0048813=GO_REF:0000019, GO:0005245=PMID:15897456, GO:0060041=GO_REF:0000019, GO:0050908=PMID:7571473, GO:0006874=GO_REF:0000019, GO:0016021=PMID:15897456, GO:0007409=GO_REF:0000019, GO:0005891=PMID:15897456, GO:0007601=PMID:9662400, GO:0046872=GO_REF:0000037} O60840 Voltage-dependent L-type calcium channel subunit alpha-1F protein 20070122 {GO:0048813=IEA, GO:0005245=IDA, GO:0060041=IEA, GO:0050908=IMP, GO:0006874=IEA, GO:0016021=IDA, GO:0007409=IEA, GO:0005891=IDA, GO:0007601=IMP, GO:0046872=IEA} axonogenesis, cellular calcium ion homeostasis, dendrite morphogenesis, detection of light stimulus involved in visual perception, retina development in camera-type eye, visual perception integral to membrane, voltage-gated calcium channel complex metal ion binding, voltage-gated calcium channel activity Human CACNA1G InterPro UniProtKB {GO:0005245=GO_REF:0000002, GO:0008332=PMID:21084288, GO:0007268=GO_REF:0000019, GO:0005891=GO_REF:0000002, GO:0010045=GO_REF:0000019, GO:0060371=GO_REF:0000019, GO:0070509=PMID:21084288, GO:0002027=GO_REF:0000019, GO:0007411=Reactome:REACT_18266, GO:0097110=PMID:21084288, GO:0042391=PMID:21084288, GO:0006810=PMID:9495342, GO:0016021=GO_REF:0000038, GO:0005216=GO_REF:0000002} Q19R18 Voltage-dependent T-type calcium channel subunit alpha-1G protein 20130413 {GO:0005245=IEA, GO:0008332=IDA, GO:0007268=IEA, GO:0005891=IEA, GO:0010045=IEA, GO:0060371=IEA, GO:0070509=IDA, GO:0002027=IEA, GO:0007411=TAS, GO:0097110=IPI, GO:0042391=IDA, GO:0006810=TAS, GO:0016021=IEA, GO:0005216=IEA} axon guidance, calcium ion import, regulation of atrial cardiac muscle cell membrane depolarization, regulation of heart rate, regulation of membrane potential, response to nickel cation, synaptic transmission, transport integral to membrane, voltage-gated calcium channel complex ion channel activity, low voltage-gated calcium channel activity, scaffold protein binding, voltage-gated calcium channel activity Human InterPro:IPR005445 CACNA1H BHF-UCL UniProtKB {GO:0008332=PMID:21084288, GO:0008016=PMID:9670923, GO:0007520=PMID:10861024, GO:0005891=GO_REF:0000002, GO:0046872=GO_REF:0000037, GO:0032870=PMID:19342457, GO:2000344=PMID:20394732, GO:0034651=PMID:19342457, GO:0042383=GO_REF:0000019, GO:0070509=PMID:21084288, GO:0007517=PMID:9670923, GO:0035865=PMID:19342457, GO:0006936=PMID:9670923, GO:0007411=Reactome:REACT_18266, GO:0005901=GO_REF:0000019, GO:0042391=PMID:21084288, GO:0097110=PMID:21084288, GO:0006810=PMID:9670923, GO:0032342=PMID:19342457, GO:0016021=PMID:21084288, GO:0005216=GO_REF:0000002} O95180 Voltage-dependent T-type calcium channel subunit alpha-1H protein 20120801 {GO:0008332=IDA, GO:0008016=TAS, GO:0007520=TAS, GO:0005891=IEA, GO:0046872=IEA, GO:0032870=IEP, GO:2000344=IMP, GO:0034651=IMP, GO:0042383=IEA, GO:0070509=IDA, GO:0007517=NAS, GO:0035865=IEP, GO:0006936=TAS, GO:0007411=TAS, GO:0005901=IEA, GO:0042391=IDA, GO:0097110=IPI, GO:0006810=TAS, GO:0032342=IMP, GO:0016021=IDA, GO:0005216=IEA} aldosterone biosynthetic process, axon guidance, calcium ion import, cellular response to hormone stimulus, cellular response to potassium ion, cortisol biosynthetic process, muscle contraction, muscle organ development, myoblast fusion, positive regulation of acrosome reaction, regulation of heart contraction, regulation of membrane potential, transport caveola, integral to membrane, sarcolemma, voltage-gated calcium channel complex ion channel activity, low voltage-gated calcium channel activity, metal ion binding, scaffold protein binding Human CACNA1I IntAct UniProtKB {GO:0005515=PMID:16740636, GO:0007165=PMID:10454147, GO:0005245=PMID:10454147, GO:0007411=Reactome:REACT_18266, GO:0008332=GO_REF:0000029, GO:0006810=PMID:10454147, GO:0006816=GO_REF:0000029, GO:0005891=GO_REF:0000029} Q9P0X4 Voltage-dependent T-type calcium channel subunit alpha-1I protein 20130415 {GO:0005515=IPI, GO:0007165=TAS, GO:0005245=TAS, GO:0007411=TAS, GO:0008332=NAS, GO:0006810=TAS, GO:0006816=NAS, GO:0005891=NAS} axon guidance, calcium ion transport, signal transduction, transport voltage-gated calcium channel complex low voltage-gated calcium channel activity, protein binding, voltage-gated calcium channel activity Human UniProtKB:Q96P56 CACNA1S Reactome UniProtKB {GO:0005886=PMID:11206130, GO:0005245=PMID:9852570, GO:0006941=GO_REF:0000019, GO:0030315=PMID:17204937, GO:0008331=PMID:9852570, GO:0007520=GO_REF:0000019, GO:0005891=PMID:9852570, GO:0046872=GO_REF:0000037, GO:0005737=PMID:11206130, GO:0001501=GO_REF:0000019, GO:0016529=GO_REF:0000019, GO:0006936=PMID:17418573, GO:0007411=Reactome:REACT_18266, GO:0007528=GO_REF:0000019, GO:0043501=GO_REF:0000019, GO:0002074=GO_REF:0000019, GO:0006816=PMID:9852570, GO:0007029=GO_REF:0000019, GO:0031674=PMID:11206130} Q13698 Voltage-dependent L-type calcium channel subunit alpha-1S protein 20130301 {GO:0005886=IDA, GO:0005245=IDA, GO:0006941=IEA, GO:0030315=IDA, GO:0008331=IDA, GO:0007520=IEA, GO:0005891=IDA, GO:0046872=IEA, GO:0005737=IDA, GO:0001501=IEA, GO:0016529=IEA, GO:0006936=IMP, GO:0007411=TAS, GO:0007528=IEA, GO:0043501=IEA, GO:0002074=IEA, GO:0006816=IDA, GO:0007029=IEA, GO:0031674=IDA} axon guidance, calcium ion transport, endoplasmic reticulum organization, extraocular skeletal muscle development, muscle contraction, myoblast fusion, neuromuscular junction development, skeletal muscle adaptation, skeletal system development, striated muscle contraction I band, T-tubule, cytoplasm, plasma membrane, sarcoplasmic reticulum, voltage-gated calcium channel complex high voltage-gated calcium channel activity, metal ion binding, voltage-gated calcium channel activity Human CACNA2D1 BHF-UCL UniProtKB {GO:0016529=GO_REF:0000019, GO:0005245=PMID:1309651, GO:0051924=PMID:1309651, GO:0030315=GO_REF:0000019, GO:0006816=PMID:1309651, GO:0005891=PMID:1309651, GO:0046872=GO_REF:0000037} P54289 Voltage-dependent calcium channel subunit alpha-2/delta-1 protein 20120917 {GO:0016529=IEA, GO:0005245=IDA, GO:0051924=IDA, GO:0030315=IEA, GO:0006816=IDA, GO:0005891=IDA, GO:0046872=IEA} calcium ion transport, regulation of calcium ion transport T-tubule, sarcoplasmic reticulum, voltage-gated calcium channel complex metal ion binding, voltage-gated calcium channel activity Human CACNA2D2 Reactome UniProtKB {GO:0006112=Reactome:REACT_1505, GO:0046622=GO_REF:0000019, GO:0050796=Reactome:REACT_18325, GO:0005886=Reactome:REACT_16913, GO:0005245=GO_REF:0000019, GO:0007528=GO_REF:0000019, GO:0040014=GO_REF:0000019, GO:0044281=Reactome:REACT_111217, GO:0060024=GO_REF:0000019, GO:0005891=GO_REF:0000019, GO:0046872=GO_REF:0000037} Q9NY47 Voltage-dependent calcium channel subunit alpha-2/delta-2 protein 20130213 {GO:0006112=TAS, GO:0046622=IEA, GO:0050796=TAS, GO:0005886=TAS, GO:0005245=IEA, GO:0007528=IEA, GO:0040014=IEA, GO:0044281=TAS, GO:0060024=IEA, GO:0005891=IEA, GO:0046872=IEA} energy reserve metabolic process, neuromuscular junction development, positive regulation of organ growth, regulation of insulin secretion, regulation of multicellular organism growth, rhythmic synaptic transmission, small molecule metabolic process plasma membrane, voltage-gated calcium channel complex metal ion binding, voltage-gated calcium channel activity Human CACNA2D3 ENSEMBL UniProtKB {GO:0005245=GO_REF:0000019, GO:0016021=GO_REF:0000037, GO:0046872=GO_REF:0000037} Q8IZS8 Voltage-dependent calcium channel subunit alpha-2/delta-3 protein 20130413 {GO:0005245=IEA, GO:0016021=IEA, GO:0046872=IEA} integral to membrane metal ion binding, voltage-gated calcium channel activity Human Ensembl:ENSRNOP00000042602 CACNA2D4 UniProtKB UniProtKB {GO:0005262=GO_REF:0000037, GO:0005244=GO_REF:0000037, GO:0016021=GO_REF:0000037, GO:0046872=GO_REF:0000037} Q7Z3S7 Voltage-dependent calcium channel subunit alpha-2/delta-4 protein 20130413 {GO:0005262=IEA, GO:0005244=IEA, GO:0016021=IEA, GO:0046872=IEA} integral to membrane calcium channel activity, metal ion binding, voltage-gated ion channel activity Human UniProtKB-KW:KW-0107 CACNB1 Reactome UniProtKB {GO:0016529=GO_REF:0000019, GO:0005245=PMID:1385409, GO:0007411=Reactome:REACT_18266, GO:0006612=GO_REF:0000019, GO:0006810=PMID:1385409, GO:0030315=GO_REF:0000019, GO:0008331=GO_REF:0000019, GO:0005891=GO_REF:0000019} Q02641 Voltage-dependent L-type calcium channel subunit beta-1 protein 20130301 {GO:0016529=IEA, GO:0005245=TAS, GO:0007411=TAS, GO:0006612=IEA, GO:0006810=TAS, GO:0030315=IEA, GO:0008331=IEA, GO:0005891=IEA} axon guidance, protein targeting to membrane, transport T-tubule, sarcoplasmic reticulum, voltage-gated calcium channel complex high voltage-gated calcium channel activity, voltage-gated calcium channel activity Human CACNB2 BHF-UCL UniProtKB {GO:0005515=PMID:17525370, GO:0005262=PMID:9594024, GO:0005245=PMID:1309651, GO:0051928=PMID:1309651, GO:0007268=GO_REF:0000019, GO:0005891=PMID:1309651, GO:0042383=GO_REF:0000039, GO:0070509=PMID:1309651, GO:0005887=PMID:9594024, GO:0007528=PMID:8494331, GO:0007411=Reactome:REACT_18266, GO:0006810=PMID:9254841, GO:0006816=GO_REF:0000029, GO:0007601=GO_REF:0000019} Q08289 Voltage-dependent L-type calcium channel subunit beta-2 protein 20120917 {GO:0005515=IPI, GO:0005262=NAS, GO:0005245=IDA, GO:0051928=IDA, GO:0007268=IEA, GO:0005891=IDA, GO:0042383=IEA, GO:0070509=IDA, GO:0005887=NAS, GO:0007528=TAS, GO:0007411=TAS, GO:0006810=TAS, GO:0006816=NAS, GO:0007601=IEA} axon guidance, calcium ion import, calcium ion transport, neuromuscular junction development, positive regulation of calcium ion transport, synaptic transmission, transport, visual perception integral to plasma membrane, sarcolemma, voltage-gated calcium channel complex calcium channel activity, protein binding, voltage-gated calcium channel activity Human CACNB3 Reactome UniProtKB {GO:0050852=GO_REF:0000019, GO:0016324=GO_REF:0000019, GO:0051899=Reactome:REACT_13606, GO:0016020=PMID:16525042, GO:0005245=PMID:11160515, GO:0007411=Reactome:REACT_18266, GO:0006810=PMID:8119293, GO:0007268=Reactome:REACT_13685, GO:0006816=PMID:11160515, GO:0005891=PMID:11160515, GO:0005829=Reactome:REACT_12594} P54284 Voltage-dependent L-type calcium channel subunit beta-3 protein 20130213 {GO:0050852=IEA, GO:0016324=IEA, GO:0051899=TAS, GO:0016020=IDA, GO:0005245=IDA, GO:0007411=TAS, GO:0006810=TAS, GO:0007268=TAS, GO:0006816=IDA, GO:0005891=IDA, GO:0005829=TAS} T cell receptor signaling pathway, axon guidance, calcium ion transport, membrane depolarization, synaptic transmission, transport apical plasma membrane, cytosol, membrane, voltage-gated calcium channel complex voltage-gated calcium channel activity Human CACNB4 Reactome UniProtKB {GO:0050852=GO_REF:0000019, GO:0051899=Reactome:REACT_13606, GO:0005245=PMID:16525042, GO:0046058=GO_REF:0000019, GO:0014051=GO_REF:0000019, GO:0006874=GO_REF:0000019, GO:0035249=GO_REF:0000019, GO:0007268=Reactome:REACT_13685, GO:0007214=GO_REF:0000019, GO:0048538=GO_REF:0000019, GO:0048536=GO_REF:0000019, GO:0005891=PMID:16525042, GO:0019227=GO_REF:0000019, GO:0005829=Reactome:REACT_12594, GO:0048541=GO_REF:0000019, GO:0007411=Reactome:REACT_18266, GO:0050908=GO_REF:0000019, GO:0007528=GO_REF:0000019, GO:0006810=PMID:9628818, GO:0007628=GO_REF:0000019, GO:0009898=PMID:16385006} O00305 Voltage-dependent L-type calcium channel subunit beta-4 protein 20130213 {GO:0050852=IEA, GO:0051899=TAS, GO:0005245=IDA, GO:0046058=IEA, GO:0014051=IEA, GO:0006874=IEA, GO:0035249=IEA, GO:0007268=TAS, GO:0007214=IEA, GO:0048538=IEA, GO:0048536=IEA, GO:0005891=IDA, GO:0019227=IEA, GO:0005829=TAS, GO:0048541=IEA, GO:0007411=TAS, GO:0050908=IEA, GO:0007528=IEA, GO:0006810=TAS, GO:0007628=IEA, GO:0009898=TAS} Peyer's patch development, T cell receptor signaling pathway, adult walking behavior, axon guidance, cAMP metabolic process, cellular calcium ion homeostasis, detection of light stimulus involved in visual perception, gamma-aminobutyric acid secretion, gamma-aminobutyric acid signaling pathway, membrane depolarization, neuromuscular junction development, neuronal action potential propagation, spleen development, synaptic transmission, synaptic transmission, glutamatergic, thymus development, transport cytosol, internal side of plasma membrane, voltage-gated calcium channel complex voltage-gated calcium channel activity Human CACNG2 Reactome UniProtKB {GO:0005515=PMID:20805473, GO:0051899=Reactome:REACT_13606, GO:0005245=GO_REF:0000019, GO:0005886=Reactome:REACT_18393, GO:2000311=GO_REF:0000024, GO:0007268=Reactome:REACT_13685, GO:0005891=GO_REF:0000002, GO:0030666=Reactome:REACT_18393, GO:0060081=GO_REF:0000019, GO:0035255=GO_REF:0000019, GO:0007528=GO_REF:0000019, GO:0032281=GO_REF:0000024, GO:0006810=PMID:10221464} Q9Y698 Voltage-dependent calcium channel gamma-2 subunit protein 20130213 {GO:0005515=IPI, GO:0051899=TAS, GO:0005245=IEA, GO:0005886=TAS, GO:2000311=ISS, GO:0007268=TAS, GO:0005891=IEA, GO:0030666=TAS, GO:0060081=IEA, GO:0035255=IEA, GO:0007528=IEA, GO:0032281=ISS, GO:0006810=TAS} membrane depolarization, membrane hyperpolarization, neuromuscular junction development, regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity, synaptic transmission, transport alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid selective glutamate receptor complex, endocytic vesicle membrane, plasma membrane, voltage-gated calcium channel complex ionotropic glutamate receptor binding, protein binding, voltage-gated calcium channel activity Human CACNG3 Reactome UniProtKB {GO:0030666=Reactome:REACT_18393, GO:0005886=Reactome:REACT_18393, GO:0005245=PMID:10221464, GO:0032281=GO_REF:0000024, GO:2000311=GO_REF:0000024, GO:0007268=Reactome:REACT_13685, GO:0006816=PMID:10221464, GO:0005891=PMID:10221464} O60359 Voltage-dependent calcium channel gamma-3 subunit protein 20130213 {GO:0030666=TAS, GO:0005886=TAS, GO:0005245=NAS, GO:0032281=ISS, GO:2000311=ISS, GO:0007268=TAS, GO:0006816=NAS, GO:0005891=NAS} calcium ion transport, regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity, synaptic transmission alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid selective glutamate receptor complex, endocytic vesicle membrane, plasma membrane, voltage-gated calcium channel complex voltage-gated calcium channel activity Human CACNG4 Reactome UniProtKB {GO:0030666=Reactome:REACT_18393, GO:0051899=Reactome:REACT_13606, GO:0005886=Reactome:REACT_18393, GO:0005245=GO_REF:0000002, GO:0005887=PMID:10613843, GO:0032281=GO_REF:0000024, GO:0006810=PMID:10613843, GO:2000311=PMID:21172611, GO:0007268=Reactome:REACT_13685, GO:0005891=GO_REF:0000002} Q9UBN1 Voltage-dependent calcium channel gamma-4 subunit protein 20130213 {GO:0030666=TAS, GO:0051899=TAS, GO:0005886=TAS, GO:0005245=IEA, GO:0005887=TAS, GO:0032281=ISS, GO:0006810=TAS, GO:2000311=IDA, GO:0007268=TAS, GO:0005891=IEA} membrane depolarization, regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity, synaptic transmission, transport alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid selective glutamate receptor complex, endocytic vesicle membrane, integral to plasma membrane, plasma membrane, voltage-gated calcium channel complex voltage-gated calcium channel activity Human CACNG7 UniProtKB UniProtKB {GO:0005245=PMID:11170751, GO:0032281=GO_REF:0000024, GO:2000311=PMID:21172611, GO:0006816=PMID:11170751, GO:0005891=PMID:11170751} P62955 Voltage-dependent calcium channel gamma-7 subunit protein 20110331 {GO:0005245=NAS, GO:0032281=ISS, GO:2000311=IDA, GO:0006816=NAS, GO:0005891=NAS} calcium ion transport, regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid selective glutamate receptor complex, voltage-gated calcium channel complex voltage-gated calcium channel activity Human CACYBP HPA UniProtKB {GO:0005515=PMID:16085652, GO:0043005=GO_REF:0000019, GO:0060416=GO_REF:0000019, GO:0007568=GO_REF:0000019, GO:0045740=GO_REF:0000019, GO:0030877=PMID:16085652, GO:0044297=GO_REF:0000019, GO:0042803=PMID:16085652, GO:0005737=GO_REF:0000052, GO:0005641=GO_REF:0000019, GO:0060548=GO_REF:0000019, GO:0071277=GO_REF:0000019, GO:0055007=GO_REF:0000019} Q9HB71 Calcyclin-binding protein protein 20100326 {GO:0005515=IPI, GO:0043005=IEA, GO:0060416=IEA, GO:0007568=IEA, GO:0045740=IEA, GO:0030877=IDA, GO:0044297=IEA, GO:0042803=IPI, GO:0005737=IDA, GO:0005641=IEA, GO:0060548=IEA, GO:0071277=IEA, GO:0055007=IEA} aging, cardiac muscle cell differentiation, cellular response to calcium ion, negative regulation of cell death, positive regulation of DNA replication, response to growth hormone stimulus beta-catenin destruction complex, cell body, cytoplasm, neuron projection, nuclear envelope lumen protein binding, protein homodimerization activity Human CAD BHF-UCL UniProtKB {GO:0017144=GO_REF:0000024, GO:0016810=GO_REF:0000002, GO:0016812=GO_REF:0000002, GO:0031100=GO_REF:0000019, GO:0005634=PMID:15890648, GO:0042995=GO_REF:0000024, GO:0044281=Reactome:REACT_111217, GO:0009790=GO_REF:0000019, GO:0014075=GO_REF:0000019, GO:0016363=PMID:9525610, GO:0046872=GO_REF:0000037, GO:0042802=GO_REF:0000024, GO:0005829=PMID:15890648, GO:0046777=GO_REF:0000024, GO:0046134=Reactome:REACT_21376, GO:0031000=GO_REF:0000019, GO:0070409=GO_REF:0000002, GO:0043195=GO_REF:0000024, GO:0018107=GO_REF:0000024, GO:0043025=GO_REF:0000024, GO:0006520=GO_REF:0000002, GO:0007565=GO_REF:0000019, GO:0044205=GO_REF:0000041, GO:0055086=Reactome:REACT_1698, GO:0004088=GO_REF:0000024, GO:0070335=GO_REF:0000024, GO:0033574=GO_REF:0000019, GO:0005524=GO_REF:0000024, GO:0035690=GO_REF:0000019, GO:0051414=GO_REF:0000019, GO:0006228=GO_REF:0000019, GO:0043234=GO_REF:0000019, GO:0004070=GO_REF:0000024, GO:0004672=GO_REF:0000024, GO:0007595=GO_REF:0000019, GO:0071364=GO_REF:0000019, GO:0004151=GO_REF:0000024, GO:0006543=GO_REF:0000002, GO:0006207=GO_REF:0000024, GO:0019899=PMID:15326225, GO:0006206=Reactome:REACT_957, GO:0016743=GO_REF:0000002, GO:0016597=GO_REF:0000002, GO:0006541=GO_REF:0000024} P27708 CAD protein protein 20110624 {GO:0017144=ISS, GO:0016810=IEA, GO:0016812=IEA, GO:0031100=IEA, GO:0005634=IDA, GO:0042995=ISS, GO:0044281=TAS, GO:0009790=IEA, GO:0014075=IEA, GO:0016363=IDA, GO:0046872=IEA, GO:0042802=ISS, GO:0005829=IDA, GO:0046777=ISS, GO:0046134=TAS, GO:0031000=IEA, GO:0070409=IEA, GO:0043195=ISS, GO:0018107=ISS, GO:0043025=ISS, GO:0006520=IEA, GO:0007565=IEA, GO:0044205=IEA, GO:0055086=TAS, GO:0004088=ISS, GO:0070335=ISS, GO:0033574=IEA, GO:0005524=ISS, GO:0035690=IEA, GO:0051414=IEA, GO:0006228=IEA, GO:0043234=IEA, GO:0004070=ISS, GO:0004672=ISS, GO:0007595=IEA, GO:0071364=IEA, GO:0004151=ISS, GO:0006543=IEA, GO:0006207=ISS, GO:0019899=IPI, GO:0006206=TAS, GO:0016743=IEA, GO:0016597=IEA, GO:0006541=ISS} 'de novo' UMP biosynthetic process, 'de novo' pyrimidine nucleobase biosynthetic process, UTP biosynthetic process, carbamoyl phosphate biosynthetic process, cellular amino acid metabolic process, cellular response to drug, cellular response to epidermal growth factor stimulus, drug metabolic process, embryo development, female pregnancy, glutamine catabolic process, glutamine metabolic process, lactation, nucleobase-containing small molecule metabolic process, organ regeneration, peptidyl-threonine phosphorylation, protein autophosphorylation, pyrimidine nucleobase metabolic process, pyrimidine nucleoside biosynthetic process, response to amine stimulus, response to caffeine, response to cortisol stimulus, response to testosterone stimulus, small molecule metabolic process cell projection, cytosol, neuronal cell body, nuclear matrix, nucleus, protein complex, terminal bouton ATP binding, amino acid binding, aspartate binding, aspartate carbamoyltransferase activity, carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity, carboxyl- or carbamoyltransferase activity, dihydroorotase activity, enzyme binding, hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides, identical protein binding, metal ion binding, protein kinase activity Human UniProtKB:D4A8A0 CADM1 Reactome UniProtKB {GO:0005515=PMID:12234973, GO:0030424=GO_REF:0000019, GO:0008037=PMID:15811952, GO:0005886=Reactome:REACT_19220, GO:0050715=PMID:15811952, GO:0007283=GO_REF:0000037, GO:0030425=GO_REF:0000019, GO:0042803=PMID:12826663, GO:0030154=GO_REF:0000037, GO:0016323=PMID:12826663, GO:0016338=GO_REF:0000019, GO:0051606=PMID:12826663, GO:0005911=PMID:12826663, GO:0042271=PMID:15811952, GO:0007156=PMID:12826663, GO:0050839=GO_REF:0000019, GO:0007157=PMID:12826663, GO:0034329=Reactome:REACT_20676, GO:0005102=PMID:15811952, GO:0006915=GO_REF:0000037, GO:0008022=PMID:12826663, GO:0030165=PMID:12826663, GO:0007416=GO_REF:0000019, GO:0045216=Reactome:REACT_19331, GO:0009826=GO_REF:0000019, GO:0008021=GO_REF:0000019, GO:0001889=GO_REF:0000019, GO:0001913=PMID:15811952, GO:0007420=GO_REF:0000019, GO:0045954=PMID:15811952, GO:0050798=PMID:15811952, GO:0016021=GO_REF:0000037, GO:0034332=Reactome:REACT_19195} Q9BY67 Cell adhesion molecule 1 protein 20090512 {GO:0005515=IPI, GO:0030424=IEA, GO:0008037=IDA, GO:0005886=TAS, GO:0050715=IDA, GO:0007283=IEA, GO:0030425=IEA, GO:0042803=ISS, GO:0030154=IEA, GO:0016323=ISS, GO:0016338=IEA, GO:0051606=ISS, GO:0005911=ISS, GO:0042271=IDA, GO:0007156=ISS, GO:0050839=IEA, GO:0007157=ISS, GO:0034329=TAS, GO:0005102=IPI, GO:0006915=IEA, GO:0008022=ISS, GO:0030165=ISS, GO:0007416=IEA, GO:0045216=TAS, GO:0009826=IEA, GO:0008021=IEA, GO:0001889=IEA, GO:0001913=IDA, GO:0007420=IEA, GO:0045954=IDA, GO:0050798=IDA, GO:0016021=IEA, GO:0034332=TAS} T cell mediated cytotoxicity, activated T cell proliferation, adherens junction organization, apoptotic process, brain development, calcium-independent cell-cell adhesion, cell differentiation, cell junction assembly, cell recognition, cell-cell junction organization, detection of stimulus, heterophilic cell-cell adhesion, homophilic cell adhesion, liver development, positive regulation of cytokine secretion, positive regulation of natural killer cell mediated cytotoxicity, spermatogenesis, susceptibility to natural killer cell mediated cytotoxicity, synapse assembly, unidimensional cell growth axon, basolateral plasma membrane, cell-cell junction, dendrite, integral to membrane, plasma membrane, synaptic vesicle PDZ domain binding, cell adhesion molecule binding, protein C-terminus binding, protein binding, protein homodimerization activity, receptor binding Human CADM3 Reactome UniProtKB {GO:0008104=GO_REF:0000019, GO:0005886=Reactome:REACT_19267, GO:0005911=PMID:12826663, GO:0034329=Reactome:REACT_20676, GO:0016021=GO_REF:0000037, GO:0007156=PMID:12826663, GO:0045216=Reactome:REACT_19331, GO:0042803=PMID:12826663, GO:0007157=PMID:12826663, GO:0034332=Reactome:REACT_19195} Q8N126 Cell adhesion molecule 3 protein 20090512 {GO:0008104=IEA, GO:0005886=TAS, GO:0005911=ISS, GO:0034329=TAS, GO:0016021=IEA, GO:0007156=ISS, GO:0045216=TAS, GO:0042803=ISS, GO:0007157=ISS, GO:0034332=TAS} adherens junction organization, cell junction assembly, cell-cell junction organization, heterophilic cell-cell adhesion, homophilic cell adhesion, protein localization cell-cell junction, integral to membrane, plasma membrane protein homodimerization activity Human CADM4 UniProtKB UniProtKB {GO:0016021=GO_REF:0000037, GO:0007155=GO_REF:0000037} Q8NFZ8 Cell adhesion molecule 4 protein 20130413 {GO:0016021=IEA, GO:0007155=IEA} cell adhesion integral to membrane Human UniProtKB-KW:KW-0812 CADPS PINC UniProtKB {GO:0005515=PMID:17984325, GO:0050432=GO_REF:0000019, GO:0016050=GO_REF:0000019, GO:0016082=GO_REF:0000019, GO:0030054=GO_REF:0000037, GO:0005543=GO_REF:0000002, GO:0045202=GO_REF:0000039, GO:0006887=PMID:1516133, GO:0015031=GO_REF:0000037, GO:0030659=GO_REF:0000039, GO:0046872=GO_REF:0000037, GO:0005829=PMID:1516133} Q9ULU8 Calcium-dependent secretion activator 1 protein 20061106 {GO:0005515=IPI, GO:0050432=IEA, GO:0016050=IEA, GO:0016082=IEA, GO:0030054=IEA, GO:0005543=IEA, GO:0045202=IEA, GO:0006887=TAS, GO:0015031=IEA, GO:0030659=IEA, GO:0046872=IEA, GO:0005829=TAS} catecholamine secretion, exocytosis, protein transport, synaptic vesicle priming, vesicle organization cell junction, cytoplasmic vesicle membrane, cytosol, synapse metal ion binding, phospholipid binding, protein binding Human CADPS2 UniProtKB UniProtKB {GO:0045921=GO_REF:0000019, GO:0042734=GO_REF:0000019, GO:0016082=GO_REF:0000019, GO:0030054=GO_REF:0000037, GO:0005543=GO_REF:0000002, GO:0045211=GO_REF:0000019, GO:0015031=GO_REF:0000037, GO:0030659=GO_REF:0000039, GO:0046872=GO_REF:0000037} Q86UW7 Calcium-dependent secretion activator 2 protein 20130413 {GO:0045921=IEA, GO:0042734=IEA, GO:0016082=IEA, GO:0030054=IEA, GO:0005543=IEA, GO:0045211=IEA, GO:0015031=IEA, GO:0030659=IEA, GO:0046872=IEA} positive regulation of exocytosis, protein transport, synaptic vesicle priming cell junction, cytoplasmic vesicle membrane, postsynaptic membrane, presynaptic membrane metal ion binding, phospholipid binding Human UniProtKB-SubCell:SL-0089 CALB1 BHF-UCL UniProtKB {GO:0005515=PMID:20098747, GO:0030424=GO_REF:0000024, GO:0071310=GO_REF:0000019, GO:0005509=GO_REF:0000002, GO:0035502=GO_REF:0000019, GO:0005634=PMID:16928804, GO:0010842=GO_REF:0000019, GO:0072205=GO_REF:0000019, GO:0072221=GO_REF:0000019, GO:0030425=GO_REF:0000019, GO:0005829=GO_REF:0000019, GO:0048167=GO_REF:0000019, GO:0072286=GO_REF:0000019, GO:0007611=GO_REF:0000019, GO:0043025=GO_REF:0000019, GO:0005499=GO_REF:0000037, GO:0007626=GO_REF:0000019} P05937 Calbindin protein 20120607 {GO:0005515=IPI, GO:0030424=ISS, GO:0071310=IEA, GO:0005509=IEA, GO:0035502=IEA, GO:0005634=IDA, GO:0010842=IEA, GO:0072205=IEA, GO:0072221=IEA, GO:0030425=IEA, GO:0005829=IEA, GO:0048167=IEA, GO:0072286=IEA, GO:0007611=IEA, GO:0043025=IEA, GO:0005499=IEA, GO:0007626=IEA} cellular response to organic substance, learning or memory, locomotory behavior, metanephric collecting duct development, metanephric connecting tubule development, metanephric distal convoluted tubule development, metanephric part of ureteric bud development, regulation of synaptic plasticity, retina layer formation axon, cytosol, dendrite, neuronal cell body, nucleus calcium ion binding, protein binding, vitamin D binding Human UniProtKB:P07171 CALB2 HPA UniProtKB {GO:0005737=GO_REF:0000052, GO:0005509=GO_REF:0000002, GO:0005921=GO_REF:0000019} P22676 Calretinin protein 20101115 {GO:0005737=IDA, GO:0005509=IEA, GO:0005921=IEA} cytoplasm, gap junction calcium ion binding Human CALCA Reactome UniProtKB {GO:0005515=PMID:9620797, GO:0009408=GO_REF:0000019, GO:0010523=PMID:16014619, GO:0005615=PMID:2408883, GO:0032403=PMID:14722252, GO:0032757=PMID:16904178, GO:0001984=GO_REF:0000019, GO:0007218=GO_REF:0000019, GO:0051482=PMID:9685362, GO:0043025=GO_REF:0000019, GO:0001944=PMID:17267696, GO:0007566=PMID:17983652, GO:0007568=GO_REF:0000019, GO:0045651=PMID:10822112, GO:0005179=GO_REF:0000037, GO:0002027=GO_REF:0000019, GO:0043542=PMID:17267696, GO:0007189=GO_REF:0000019, GO:0045892=PMID:11014233, GO:0007631=GO_REF:0000019, GO:0032730=PMID:16904178, GO:0030819=PMID:14722252, GO:0007267=PMID:2408883, GO:0005634=GO_REF:0000019, GO:0045778=GO_REF:0000019, GO:0007204=PMID:17983652, GO:0045779=PMID:10822112, GO:0032147=PMID:17983652, GO:0007190=PMID:16014619, GO:0005737=PMID:17267696, GO:0030279=GO_REF:0000019, GO:0006954=GO_REF:0000019, GO:0045986=GO_REF:0000019, GO:0043195=GO_REF:0000019, GO:0042311=GO_REF:0000002, GO:0045909=PMID:3266556, GO:0007159=PMID:1326102, GO:0050965=GO_REF:0000019, GO:0031645=GO_REF:0000019, GO:0051480=PMID:9685362, GO:0050727=GO_REF:0000019, GO:0005102=PMID:16014619, GO:0031716=PMID:8940110, GO:0005576=Reactome:REACT_22268, GO:0045762=PMID:8078488, GO:0045671=PMID:10822112, GO:0002548=PMID:15248232, GO:0001935=PMID:17267696, GO:0008217=PMID:1318039, GO:0048265=GO_REF:0000019} P06881 Calcitonin gene-related peptide 1 protein 20090507 {GO:0005515=IPI, GO:0009408=IEA, GO:0010523=IDA, GO:0005615=IDA, GO:0032403=IDA, GO:0032757=IDA, GO:0001984=IEA, GO:0007218=IEA, GO:0051482=IDA, GO:0043025=IEA, GO:0001944=IDA, GO:0007566=IDA, GO:0007568=IEA, GO:0045651=IDA, GO:0005179=IEA, GO:0002027=IEA, GO:0043542=IDA, GO:0007189=IEA, GO:0045892=IDA, GO:0007631=IEA, GO:0032730=IDA, GO:0030819=IDA, GO:0007267=TAS, GO:0005634=IEA, GO:0045778=IEA, GO:0007204=IDA, GO:0045779=IDA, GO:0032147=IDA, GO:0007190=IDA, GO:0005737=IDA, GO:0030279=IEA, GO:0006954=IEA, GO:0045986=IEA, GO:0043195=IEA, GO:0042311=IEA, GO:0045909=IDA, GO:0007159=IDA, GO:0050965=IEA, GO:0031645=IEA, GO:0051480=IDA, GO:0050727=IEA, GO:0005102=IDA, GO:0031716=IPI, GO:0005576=TAS, GO:0045762=IDA, GO:0045671=IDA, GO:0002548=IDA, GO:0001935=IDA, GO:0008217=NAS, GO:0048265=IEA} activation of adenylate cyclase activity, activation of protein kinase activity, adenylate cyclase-activating G-protein coupled receptor signaling pathway, aging, cell-cell signaling, cytosolic calcium ion homeostasis, detection of temperature stimulus involved in sensory perception of pain, elevation of cytosolic calcium ion concentration, elevation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway, embryo implantation, endothelial cell migration, endothelial cell proliferation, feeding behavior, inflammatory response, leukocyte cell-cell adhesion, monocyte chemotaxis, negative regulation of bone resorption, negative regulation of calcium ion transport into cytosol, negative regulation of neurological system process, negative regulation of ossification, negative regulation of osteoclast differentiation, negative regulation of smooth muscle contraction, negative regulation of transcription, DNA-dependent, neuropeptide signaling pathway, positive regulation of adenylate cyclase activity, positive regulation of cAMP biosynthetic process, positive regulation of interleukin-1 alpha production, positive regulation of interleukin-8 production, positive regulation of macrophage differentiation, positive regulation of ossification, positive regulation of vasodilation, regulation of blood pressure, regulation of heart rate, regulation of inflammatory response, response to heat, response to pain, vasculature development, vasodilation, vasodilation of artery involved in baroreceptor response to increased systemic arterial blood pressure cytoplasm, extracellular region, extracellular space, neuronal cell body, nucleus, terminal bouton calcitonin receptor binding, hormone activity, protein binding, protein complex binding, receptor binding Human CALCOCO1 HPA UniProtKB {GO:0003712=PMID:16344550, GO:0005515=PMID:16344550, GO:0000790=GO_REF:0000019, GO:0008013=PMID:16344550, GO:0044212=PMID:16344550, GO:0003713=GO_REF:0000024, GO:0005634=GO_REF:0000054, GO:0008022=PMID:16344550, GO:0006351=GO_REF:0000024, GO:0043231=GO_REF:0000052, GO:0043565=PMID:16344550, GO:0007165=GO_REF:0000024, GO:0005737=GO_REF:0000052, GO:0030374=PMID:16344550, GO:0030518=GO_REF:0000024, GO:0003682=GO_REF:0000019, GO:0045944=GO_REF:0000019, GO:0016055=GO_REF:0000037, GO:0045893=PMID:16344550, GO:0070016=PMID:16344550} Q9P1Z2 Calcium-binding and coiled-coil domain-containing protein 1 protein 20111111 {GO:0003712=IDA, GO:0005515=IPI, GO:0000790=IEA, GO:0008013=IPI, GO:0044212=IDA, GO:0003713=ISS, GO:0005634=IDA, GO:0008022=IPI, GO:0006351=ISS, GO:0043231=IDA, GO:0043565=IDA, GO:0007165=ISS, GO:0005737=IDA, GO:0030374=IDA, GO:0030518=ISS, GO:0003682=IEA, GO:0045944=IEA, GO:0016055=IEA, GO:0045893=IMP, GO:0070016=IPI} Wnt receptor signaling pathway, intracellular steroid hormone receptor signaling pathway, positive regulation of transcription from RNA polymerase II promoter, positive regulation of transcription, DNA-dependent, signal transduction, transcription, DNA-dependent cytoplasm, intracellular membrane-bounded organelle, nuclear chromatin, nucleus armadillo repeat domain binding, beta-catenin binding, chromatin binding, ligand-dependent nuclear receptor transcription coactivator activity, protein C-terminus binding, protein binding, sequence-specific DNA binding, transcription coactivator activity, transcription cofactor activity, transcription regulatory region DNA binding Human CALCOCO2 HPA UniProtKB {GO:0005515=PMID:21903422, GO:0048471=PMID:9230084, GO:0005737=GO_REF:0000052, GO:0005794=GO_REF:0000039, GO:0005730=GO_REF:0000052, GO:0016032=PMID:7540613, GO:0005634=GO_REF:0000052, GO:0034341=PMID:9230084, GO:0005856=GO_REF:0000039, GO:0042803=PMID:9230084, GO:0043231=GO_REF:0000052} Q13137 Calcium-binding and coiled-coil domain-containing protein 2 protein 20101115 {GO:0005515=IPI, GO:0048471=IDA, GO:0005737=IDA, GO:0005794=IEA, GO:0005730=IDA, GO:0016032=TAS, GO:0005634=IDA, GO:0034341=IDA, GO:0005856=IEA, GO:0042803=IPI, GO:0043231=IDA} response to interferon-gamma, viral reproduction Golgi apparatus, cytoplasm, cytoskeleton, intracellular membrane-bounded organelle, nucleolus, nucleus, perinuclear region of cytoplasm protein binding, protein homodimerization activity Human CALCR Reactome UniProtKB {GO:0005515=PMID:7588285, GO:0004948=GO_REF:0000002, GO:0030424=GO_REF:0000019, GO:0032841=PMID:8078488, GO:0043488=GO_REF:0000019, GO:0005886=Reactome:REACT_22268, GO:0001669=GO_REF:0000019, GO:0030819=PMID:14722252, GO:0030316=GO_REF:0000019, GO:0051384=PMID:11250927, GO:0045762=PMID:15563840, GO:0015031=PMID:14722252, GO:0007204=GO_REF:0000019, GO:0031623=PMID:10882736, GO:0030279=GO_REF:0000019, GO:0005887=PMID:7588285, GO:0008565=PMID:14722252, GO:0043025=GO_REF:0000019, GO:0016021=GO_REF:0000038, GO:0007189=PMID:7619207} P30988 Calcitonin receptor protein 20090507 {GO:0005515=IPI, GO:0004948=IEA, GO:0030424=IEA, GO:0032841=IDA, GO:0043488=IEA, GO:0005886=TAS, GO:0001669=IEA, GO:0030819=IDA, GO:0030316=IEA, GO:0051384=IDA, GO:0045762=IDA, GO:0015031=IDA, GO:0007204=IEA, GO:0031623=IDA, GO:0030279=IEA, GO:0005887=NAS, GO:0008565=IDA, GO:0043025=IEA, GO:0016021=IEA, GO:0007189=IDA} adenylate cyclase-activating G-protein coupled receptor signaling pathway, elevation of cytosolic calcium ion concentration, negative regulation of ossification, osteoclast differentiation, positive regulation of adenylate cyclase activity, positive regulation of cAMP biosynthetic process, protein transport, receptor internalization, regulation of mRNA stability, response to glucocorticoid stimulus acrosomal vesicle, axon, integral to membrane, integral to plasma membrane, neuronal cell body, plasma membrane calcitonin binding, calcitonin receptor activity, protein binding, protein transporter activity Human CALCRL BHF-UCL UniProtKB {GO:0004948=GO_REF:0000019, GO:0005515=PMID:9620797, GO:0005886=PMID:18039931, GO:0004930=PMID:7818539, GO:0005783=PMID:10882736, GO:0001525=PMID:20596610, GO:0015031=PMID:9620797, GO:0048661=GO_REF:0000019, GO:0007507=GO_REF:0000019, GO:0031623=PMID:20074556, GO:0006937=GO_REF:0000019, GO:0016020=GO_REF:0000002, GO:0007187=PMID:7818539, GO:0005887=PMID:7818539, GO:0001605=PMID:22102369, GO:0050728=GO_REF:0000019, GO:0071329=PMID:10882736, GO:0008565=PMID:9620797, GO:0006171=PMID:20074556, GO:0006816=PMID:10882736, GO:0007189=GO_REF:0000019, GO:0001635=GO_REF:0000019} Q16602 Calcitonin gene-related peptide type 1 receptor protein 20080908 {GO:0004948=IEA, GO:0005515=IPI, GO:0005886=IDA, GO:0004930=TAS, GO:0005783=IDA, GO:0001525=IDA, GO:0015031=IDA, GO:0048661=IEA, GO:0007507=IEA, GO:0031623=IDA, GO:0006937=IEA, GO:0016020=IEA, GO:0007187=TAS, GO:0005887=TAS, GO:0001605=IDA, GO:0050728=IEA, GO:0071329=IDA, GO:0008565=IDA, GO:0006171=IDA, GO:0006816=IDA, GO:0007189=IEA, GO:0001635=IEA} G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger, adenylate cyclase-activating G-protein coupled receptor signaling pathway, angiogenesis, cAMP biosynthetic process, calcium ion transport, cellular response to sucrose stimulus, heart development, negative regulation of inflammatory response, positive regulation of smooth muscle cell proliferation, protein transport, receptor internalization, regulation of muscle contraction endoplasmic reticulum, integral to plasma membrane, membrane, plasma membrane G-protein coupled receptor activity, adrenomedullin receptor activity, calcitonin gene-related polypeptide receptor activity, calcitonin receptor activity, protein binding, protein transporter activity Human CALD1 HPA UniProtKB {GO:0005516=GO_REF:0000037, GO:0005886=GO_REF:0000052, GO:0030478=GO_REF:0000019, GO:0006928=PMID:16130169, GO:0003779=GO_REF:0000037, GO:0015629=GO_REF:0000052, GO:0030016=GO_REF:0000039, GO:0005829=Reactome:REACT_20663, GO:0006936=Reactome:REACT_20558, GO:0016020=GO_REF:0000019, GO:0017022=GO_REF:0000002, GO:0005856=PMID:16130169, GO:0005523=PMID:1555769} Q05682 Caldesmon protein 20110516 {GO:0005516=IEA, GO:0005886=IDA, GO:0030478=IEA, GO:0006928=TAS, GO:0003779=IEA, GO:0015629=IDA, GO:0030016=IEA, GO:0005829=TAS, GO:0006936=TAS, GO:0016020=IEA, GO:0017022=IEA, GO:0005856=TAS, GO:0005523=TAS} cellular component movement, muscle contraction actin cap, actin cytoskeleton, cytoskeleton, cytosol, membrane, myofibril, plasma membrane actin binding, calmodulin binding, myosin binding, tropomyosin binding Human CALM1 BHF-UCL UniProtKB {GO:0005515=PMID:21167176, GO:0005513=PMID:23040497, GO:0072542=PMID:8631777, GO:0006936=Reactome:REACT_20558, GO:0007173=Reactome:REACT_9417, GO:0043274=PMID:12821674, GO:0005813=PMID:16760425, GO:0032465=PMID:16760425, GO:0005975=Reactome:REACT_474, GO:0051343=PMID:8631777, GO:0005509=PMID:8631777, GO:0019904=PMID:11984006, GO:0030168=Reactome:REACT_798, GO:0031432=PMID:7607248, GO:0044325=PMID:23040497, GO:0051592=PMID:7607248, GO:0000922=PMID:16760425, GO:0007186=PMID:10899953, GO:0002027=PMID:23040497, GO:0008543=Reactome:REACT_9470, GO:0045087=Reactome:REACT_6802, GO:0055117=PMID:23040497, GO:0005654=Reactome:REACT_20666, GO:0030801=PMID:8631777, GO:0005980=Reactome:REACT_1008, GO:0016044=Reactome:REACT_11123, GO:0005886=Reactome:REACT_12620, GO:0043647=Reactome:REACT_150312, GO:0050999=Reactome:REACT_12477, GO:0007268=Reactome:REACT_13685, GO:0031996=PMID:16127172, GO:0007202=Reactome:REACT_12079, GO:0031997=PMID:15632291, GO:0044281=Reactome:REACT_111217, GO:0005829=Reactome:REACT_150282, GO:0005737=PMID:10899953, GO:0060315=GO_REF:0000024, GO:0006006=Reactome:REACT_723, GO:0005876=PMID:16760425, GO:0046209=Reactome:REACT_12508, GO:0048011=Reactome:REACT_11061, GO:0035307=PMID:8631777, GO:1901844=GO_REF:0000036, GO:0010881=GO_REF:0000036, GO:0005576=Reactome:REACT_21347, GO:0034704=PMID:23040497, GO:0007165=Reactome:REACT_12478, GO:0007596=Reactome:REACT_604, GO:0002576=Reactome:REACT_318, GO:0032516=PMID:8631777} P62158 Calmodulin protein 20130211 {GO:0005515=IPI, GO:0005513=IMP, GO:0072542=IDA, GO:0006936=TAS, GO:0007173=TAS, GO:0043274=IPI, GO:0005813=IDA, GO:0032465=IMP, GO:0005975=TAS, GO:0051343=IDA, GO:0005509=IDA, GO:0019904=IPI, GO:0030168=TAS, GO:0031432=IPI, GO:0044325=IPI, GO:0051592=IDA, GO:0000922=IDA, GO:0007186=TAS, GO:0002027=IMP, GO:0008543=TAS, GO:0045087=TAS, GO:0055117=IMP, GO:0005654=TAS, GO:0030801=IDA, GO:0005980=TAS, GO:0016044=TAS, GO:0005886=TAS, GO:0043647=TAS, GO:0050999=TAS, GO:0007268=TAS, GO:0031996=IPI, GO:0007202=TAS, GO:0031997=IPI, GO:0044281=TAS, GO:0005829=TAS, GO:0005737=TAS, GO:0060315=ISS, GO:0006006=TAS, GO:0005876=IDA, GO:0046209=TAS, GO:0048011=TAS, GO:0035307=IDA, GO:1901844=IC, GO:0010881=IC, GO:0005576=TAS, GO:0034704=IDA, GO:0007165=TAS, GO:0007596=TAS, GO:0002576=TAS, GO:0032516=IDA} G-protein coupled receptor signaling pathway, activation of phospholipase C activity, blood coagulation, carbohydrate metabolic process, cellular membrane organization, detection of calcium ion, epidermal growth factor receptor signaling pathway, fibroblast growth factor receptor signaling pathway, glucose metabolic process, glycogen catabolic process, innate immune response, inositol phosphate metabolic process, muscle contraction, negative regulation of ryanodine-sensitive calcium-release channel activity, neurotrophin TRK receptor signaling pathway, nitric oxide metabolic process, platelet activation, platelet degranulation, positive regulation of cyclic nucleotide metabolic process, positive regulation of cyclic-nucleotide phosphodiesterase activity, positive regulation of phosphoprotein phosphatase activity, positive regulation of protein dephosphorylation, regulation of cardiac muscle contraction, regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion, regulation of cell communication by electrical coupling involved in cardiac conduction, regulation of cytokinesis, regulation of heart rate, regulation of nitric-oxide synthase activity, response to calcium ion, signal transduction, small molecule metabolic process, synaptic transmission calcium channel complex, centrosome, cytoplasm, cytosol, extracellular region, nucleoplasm, plasma membrane, spindle microtubule, spindle pole N-terminal myristoylation domain binding, calcium ion binding, ion channel binding, phospholipase binding, protein binding, protein domain specific binding, protein phosphatase activator activity, thioesterase binding, titin binding Human GO:0055117|GO:0060316 CALM2 InterPro UniProtKB {GO:0005509=GO_REF:0000002} H0Y7A7 Calmodulin protein 20130413 {GO:0005509=IEA} calcium ion binding Human InterPro:IPR001125|InterPro:IPR002048|InterPro:IPR011992 CALM3 UniProtKB UniProtKB {GO:0016301=GO_REF:0000038, GO:0005509=GO_REF:0000002} Q96HY3 Calmodulin 3 (Phosphorylase kinase, delta), isoform CRA_a protein 20130413 {GO:0016301=IEA, GO:0005509=IEA} calcium ion binding, kinase activity Human UniProtKB-KW:KW-0418 CALML3 InterPro UniProtKB {GO:0005509=GO_REF:0000002} P27482 Calmodulin-like protein 3 protein 20130413 {GO:0005509=IEA} calcium ion binding Human InterPro:IPR002048|InterPro:IPR011992 CALML5 PINC UniProtKB {GO:0007165=PMID:10777582, GO:0008544=PMID:10777582, GO:0005509=GO_REF:0000019} Q9NZT1 Calmodulin-like protein 5 protein 20030904 {GO:0007165=TAS, GO:0008544=TAS, GO:0005509=IEA} epidermis development, signal transduction calcium ion binding Human CALR BHF-UCL UniProtKB {GO:0017148=PMID:12242300, GO:0005515=PMID:17055437, GO:0002474=Reactome:REACT_75820, GO:0034504=PMID:15998798, GO:0050681=PMID:8107809, GO:0007283=GO_REF:0000019, GO:2000510=PMID:16140380, GO:0030968=Reactome:REACT_18356, GO:0005622=PMID:7841019, GO:1900026=PMID:11859136, GO:0006457=PMID:15474971, GO:0006611=PMID:11149926, GO:0055007=GO_REF:0000019, GO:0032355=GO_REF:0000019, GO:0031625=PMID:8666824, GO:0018279=Reactome:REACT_22426, GO:0071285=GO_REF:0000019, GO:0051208=PMID:15474971, GO:0005794=GO_REF:0000019, GO:0009986=PMID:15474971, GO:0005506=GO_REF:0000019, GO:0001849=PMID:15474971, GO:0045740=PMID:14726956, GO:0005509=GO_REF:0000024, GO:0000122=PMID:8107809, GO:0045787=PMID:14726956, GO:0005178=PMID:1911778, GO:0048387=PMID:8107809, GO:0042921=PMID:8107809, GO:0005788=Reactome:REACT_116001, GO:0008270=PMID:15474971, GO:0051082=PMID:15474971, GO:0006987=Reactome:REACT_18348, GO:0005844=PMID:14726956, GO:0044267=Reactome:REACT_17015, GO:0045892=PMID:8107809, GO:0009897=GO_REF:0000019, GO:0090398=PMID:14726956, GO:0043687=Reactome:REACT_22161, GO:0048471=PMID:1911778, GO:0042824=PMID:11825569, GO:0008284=PMID:14726956, GO:0005783=PMID:16130169, GO:0042562=GO_REF:0000019, GO:0051087=PMID:15474971, GO:0033144=PMID:8107809, GO:0005634=PMID:8107809, GO:0003729=PMID:14726956, GO:0005829=PMID:11149926, GO:0022417=PMID:17563366, GO:0005737=PMID:1911778, GO:0050766=GO_REF:0000024, GO:0071556=Reactome:REACT_75922, GO:0007050=PMID:14726956, GO:0002502=PMID:11825569, GO:0042277=GO_REF:0000019, GO:0006355=PMID:8107808, GO:0001669=GO_REF:0000019, GO:0042493=GO_REF:0000019, GO:0005578=GO_REF:0000039, GO:0042590=Reactome:REACT_111119, GO:0050821=PMID:10581245, GO:0033018=GO_REF:0000039, GO:0006874=PMID:11149926, GO:0042981=PMID:16130169, GO:0033574=GO_REF:0000019, GO:0003677=PMID:11149926, GO:0040020=GO_REF:0000019, GO:0010628=GO_REF:0000019, GO:0045665=PMID:8107809, GO:0044183=PMID:15474971, GO:0030866=GO_REF:0000019, GO:0030246=PMID:15474971, GO:0002479=Reactome:REACT_111178} P27797 Calreticulin protein 20100524 {GO:0017148=TAS, GO:0005515=IPI, GO:0002474=TAS, GO:0034504=IDA, GO:0050681=IDA, GO:0007283=IEA, GO:2000510=IMP, GO:0030968=TAS, GO:0005622=TAS, GO:1900026=IMP, GO:0006457=TAS, GO:0006611=IDA, GO:0055007=IEA, GO:0032355=IEA, GO:0031625=IPI, GO:0018279=TAS, GO:0071285=IEA, GO:0051208=TAS, GO:0005794=IEA, GO:0009986=TAS, GO:0005506=IEA, GO:0001849=TAS, GO:0045740=IGI, GO:0005509=ISS, GO:0000122=IDA, GO:0045787=IGI, GO:0005178=IPI, GO:0048387=IDA, GO:0042921=TAS, GO:0005788=TAS, GO:0008270=TAS, GO:0051082=TAS, GO:0006987=TAS, GO:0005844=ISS, GO:0044267=TAS, GO:0045892=IDA, GO:0009897=IEA, GO:0090398=IGI, GO:0043687=TAS, GO:0048471=IDA, GO:0042824=ISS, GO:0008284=IGI, GO:0005783=TAS, GO:0042562=IEA, GO:0051087=TAS, GO:0033144=IDA, GO:0005634=IDA, GO:0003729=IDA, GO:0005829=IDA, GO:0022417=TAS, GO:0005737=IDA, GO:0050766=ISS, GO:0071556=TAS, GO:0007050=IGI, GO:0002502=ISS, GO:0042277=IEA, GO:0006355=TAS, GO:0001669=IEA, GO:0042493=IEA, GO:0005578=IEA, GO:0042590=TAS, GO:0050821=TAS, GO:0033018=IEA, GO:0006874=TAS, GO:0042981=TAS, GO:0033574=IEA, GO:0003677=NAS, GO:0040020=IEA, GO:0010628=IEA, GO:0045665=IDA, GO:0044183=TAS, GO:0030866=IEA, GO:0030246=TAS, GO:0002479=TAS} activation of signaling protein activity involved in unfolded protein response, antigen processing and presentation of exogenous peptide antigen via MHC class I, antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent, antigen processing and presentation of peptide antigen via MHC class I, cardiac muscle cell differentiation, cell cycle arrest, cellular calcium ion homeostasis, cellular protein metabolic process, cellular response to lithium ion, cellular senescence, cortical actin cytoskeleton organization, endoplasmic reticulum unfolded protein response, glucocorticoid receptor signaling pathway, negative regulation of intracellular steroid hormone receptor signaling pathway, negative regulation of neuron differentiation, negative regulation of retinoic acid receptor signaling pathway, negative regulation of transcription from RNA polymerase II promoter, negative regulation of transcription, DNA-dependent, negative regulation of translation, peptide antigen assembly with MHC class I protein complex, positive regulation of DNA replication, positive regulation of cell cycle, positive regulation of cell proliferation, positive regulation of dendritic cell chemotaxis, positive regulation of gene expression, positive regulation of phagocytosis, positive regulation of substrate adhesion-dependent cell spreading, post-translational protein modification, protein N-linked glycosylation via asparagine, protein export from nucleus, protein folding, protein localization to nucleus, protein maturation by protein folding, protein stabilization, regulation of apoptotic process, regulation of meiosis, regulation of transcription, DNA-dependent, response to drug, response to estradiol stimulus, response to testosterone stimulus, sequestering of calcium ion, spermatogenesis Golgi apparatus, MHC class I peptide loading complex, acrosomal vesicle, cell surface, cytoplasm, cytosol, endoplasmic reticulum, endoplasmic reticulum lumen, external side of plasma membrane, integral to lumenal side of endoplasmic reticulum membrane, intracellular, nucleus, perinuclear region of cytoplasm, polysome, proteinaceous extracellular matrix, sarcoplasmic reticulum lumen DNA binding, androgen receptor binding, calcium ion binding, carbohydrate binding, chaperone binding, complement component C1q binding, hormone binding, integrin binding, iron ion binding, mRNA binding, peptide binding, protein binding, protein binding involved in protein folding, ubiquitin protein ligase binding, unfolded protein binding, zinc ion binding Human CALR3 UniProtKB UniProtKB {GO:0006457=GO_REF:0000002, GO:0005783=GO_REF:0000002, GO:0005509=GO_REF:0000002, GO:0005788=GO_REF:0000039, GO:0007283=GO_REF:0000037, GO:0051082=GO_REF:0000002, GO:0030154=GO_REF:0000037} Q96L12 Calreticulin-3 protein 20130413 {GO:0006457=IEA, GO:0005783=IEA, GO:0005509=IEA, GO:0005788=IEA, GO:0007283=IEA, GO:0051082=IEA, GO:0030154=IEA} cell differentiation, protein folding, spermatogenesis endoplasmic reticulum, endoplasmic reticulum lumen calcium ion binding, unfolded protein binding Human UniProtKB-SubCell:SL-0096 CALU HPA UniProtKB {GO:0005515=PMID:18688696, GO:0008150=GO_REF:0000015, GO:0042470=GO_REF:0000039, GO:0005794=PMID:9218460, GO:0007596=Reactome:REACT_604, GO:0005783=GO_REF:0000052, GO:0002576=Reactome:REACT_318, GO:0005509=PMID:10094503, GO:0033018=GO_REF:0000039, GO:0030168=Reactome:REACT_798, GO:0005576=GO_REF:0000039} O43852 Calumenin protein 20080205 {GO:0005515=IPI, GO:0008150=ND, GO:0042470=IEA, GO:0005794=TAS, GO:0007596=TAS, GO:0005783=IDA, GO:0002576=TAS, GO:0005509=IDA, GO:0033018=IEA, GO:0030168=TAS, GO:0005576=IEA} biological_process, blood coagulation, platelet activation, platelet degranulation Golgi apparatus, endoplasmic reticulum, extracellular region, melanosome, sarcoplasmic reticulum lumen calcium ion binding, protein binding Human CALY UniProtKB UniProtKB {GO:0045807=PMID:16595675, GO:0032051=PMID:16595675, GO:0005887=PMID:14534309, GO:0031410=PMID:16595675, GO:0007212=GO_REF:0000002, GO:0030659=GO_REF:0000039, GO:0048268=PMID:16595675, GO:0006897=GO_REF:0000037} Q9NYX4 Neuron-specific vesicular protein calcyon protein 20080527 {GO:0045807=IMP, GO:0032051=IDA, GO:0005887=IDA, GO:0031410=IDA, GO:0007212=IEA, GO:0030659=IEA, GO:0048268=IDA, GO:0006897=IEA} clathrin coat assembly, dopamine receptor signaling pathway, endocytosis, positive regulation of endocytosis cytoplasmic vesicle, cytoplasmic vesicle membrane, integral to plasma membrane clathrin light chain binding Human CAMK1 BHF-UCL UniProtKB {GO:0005515=PMID:17442826, GO:0005516=GO_REF:0000037, GO:0071902=PMID:17442826, GO:0043393=PMID:11114197, GO:0005634=GO_REF:0000039, GO:0005524=GO_REF:0000037, GO:0006913=GO_REF:0000019, GO:0046827=GO_REF:0000019, GO:0032880=PMID:11114197, GO:0007165=GO_REF:0000019, GO:0007049=GO_REF:0000037, GO:0005737=GO_REF:0000039, GO:0051149=PMID:11081517, GO:0004672=GO_REF:0000002, GO:0004674=GO_REF:0000038, GO:0051835=PMID:18184567, GO:0010976=PMID:17442826, GO:0006468=PMID:11114197, GO:0004683=GO_REF:0000024, GO:0060999=PMID:18184567, GO:0051147=PMID:11114197} Q14012 Calcium/calmodulin-dependent protein kinase type 1 protein 20090805 {GO:0005515=IPI, GO:0005516=IEA, GO:0071902=IDA, GO:0043393=IDA, GO:0005634=IEA, GO:0005524=IEA, GO:0006913=IEA, GO:0046827=IEA, GO:0032880=IDA, GO:0007165=IEA, GO:0007049=IEA, GO:0005737=IEA, GO:0051149=IMP, GO:0004672=IEA, GO:0004674=IEA, GO:0051835=IMP, GO:0010976=IDA, GO:0006468=IDA, GO:0004683=ISS, GO:0060999=IMP, GO:0051147=IDA} cell cycle, nucleocytoplasmic transport, positive regulation of dendritic spine development, positive regulation of muscle cell differentiation, positive regulation of neuron projection development, positive regulation of protein export from nucleus, positive regulation of protein serine/threonine kinase activity, positive regulation of synapse structural plasticity, protein phosphorylation, regulation of muscle cell differentiation, regulation of protein binding, regulation of protein localization, signal transduction cytoplasm, nucleus ATP binding, calmodulin binding, calmodulin-dependent protein kinase activity, protein binding, protein kinase activity, protein serine/threonine kinase activity Human CAMK1D UniProtKB UniProtKB {GO:0005516=GO_REF:0000037, GO:0042981=GO_REF:0000019, GO:0071622=PMID:15840691, GO:0005634=PMID:16324104, GO:0005524=GO_REF:0000037, GO:0060267=PMID:15840691, GO:0032793=PMID:16324104, GO:0050766=PMID:15840691, GO:0005737=PMID:16324104, GO:0006954=GO_REF:0000037, GO:0010976=GO_REF:0000024, GO:0090023=GO_REF:0000024, GO:0050773=PMID:17056143, GO:0004683=GO_REF:0000003, GO:0005954=PMID:11264466} Q8IU85 Calcium/calmodulin-dependent protein kinase type 1D protein 20110913 {GO:0005516=IEA, GO:0042981=IEA, GO:0071622=IMP, GO:0005634=IDA, GO:0005524=IEA, GO:0060267=IMP, GO:0032793=IDA, GO:0050766=IMP, GO:0005737=IDA, GO:0006954=IEA, GO:0010976=ISS, GO:0090023=ISS, GO:0050773=IMP, GO:0004683=IEA, GO:0005954=TAS} inflammatory response, positive regulation of CREB transcription factor activity, positive regulation of neuron projection development, positive regulation of neutrophil chemotaxis, positive regulation of phagocytosis, positive regulation of respiratory burst, regulation of apoptotic process, regulation of dendrite development, regulation of granulocyte chemotaxis calcium- and calmodulin-dependent protein kinase complex, cytoplasm, nucleus ATP binding, calmodulin binding, calmodulin-dependent protein kinase activity Human UniProtKB:Q8BW96 CAMK1G UniProtKB UniProtKB {GO:0043005=GO_REF:0000019, GO:0005516=GO_REF:0000037, GO:0005886=GO_REF:0000039, GO:0000139=GO_REF:0000039, GO:0004674=GO_REF:0000038, GO:0004683=GO_REF:0000003, GO:0005524=GO_REF:0000037, GO:0005954=GO_REF:0000019} Q96NX5 Calcium/calmodulin-dependent protein kinase type 1G protein 20130413 {GO:0043005=IEA, GO:0005516=IEA, GO:0005886=IEA, GO:0000139=IEA, GO:0004674=IEA, GO:0004683=IEA, GO:0005524=IEA, GO:0005954=IEA} Golgi membrane, calcium- and calmodulin-dependent protein kinase complex, neuron projection, plasma membrane ATP binding, calmodulin binding, calmodulin-dependent protein kinase activity, protein serine/threonine kinase activity Human UniProtKB-SubCell:SL-0039 CAMK2A Reactome UniProtKB {GO:0005515=PMID:17052756, GO:0005516=GO_REF:0000037, GO:0030054=GO_REF:0000037, GO:0005886=Reactome:REACT_20670, GO:0019221=Reactome:REACT_25229, GO:0007268=Reactome:REACT_13685, GO:0046928=GO_REF:0000019, GO:0005524=GO_REF:0000037, GO:0005829=Reactome:REACT_25369, GO:0030666=Reactome:REACT_18393, GO:0042734=GO_REF:0000039, GO:0000082=GO_REF:0000019, GO:0051092=PMID:17052756, GO:0046777=GO_REF:0000019, GO:0048168=GO_REF:0000019, GO:0016301=PMID:17052756, GO:0004674=GO_REF:0000019, GO:0035254=GO_REF:0000019, GO:0005654=Reactome:REACT_20634, GO:0006468=PMID:17052756, GO:0006816=GO_REF:0000019, GO:0004683=GO_REF:0000003, GO:0060333=Reactome:REACT_25078} Q9UQM7 Calcium/calmodulin-dependent protein kinase type II subunit alpha protein 20130228 {GO:0005515=IPI, GO:0005516=IEA, GO:0030054=IEA, GO:0005886=TAS, GO:0019221=TAS, GO:0007268=TAS, GO:0046928=IEA, GO:0005524=IEA, GO:0005829=TAS, GO:0030666=TAS, GO:0042734=IEA, GO:0000082=IEA, GO:0051092=IMP, GO:0046777=IEA, GO:0048168=IEA, GO:0016301=IDA, GO:0004674=IEA, GO:0035254=IEA, GO:0005654=TAS, GO:0006468=IDA, GO:0006816=IEA, GO:0004683=IEA, GO:0060333=TAS} G1/S transition of mitotic cell cycle, calcium ion transport, cytokine-mediated signaling pathway, interferon-gamma-mediated signaling pathway, positive regulation of NF-kappaB transcription factor activity, protein autophosphorylation, protein phosphorylation, regulation of neuronal synaptic plasticity, regulation of neurotransmitter secretion, synaptic transmission cell junction, cytosol, endocytic vesicle membrane, nucleoplasm, plasma membrane, presynaptic membrane ATP binding, calmodulin binding, calmodulin-dependent protein kinase activity, glutamate receptor binding, kinase activity, protein binding, protein serine/threonine kinase activity Human CAMK2B Reactome UniProtKB {GO:0005516=GO_REF:0000037, GO:0090129=GO_REF:0000024, GO:0005886=Reactome:REACT_20670, GO:0019221=Reactome:REACT_25229, GO:2001235=GO_REF:0000019, GO:0007268=Reactome:REACT_13685, GO:0051233=GO_REF:0000019, GO:0005829=Reactome:REACT_25369, GO:0000082=GO_REF:0000019, GO:0051823=PMID:18817731, GO:0046777=PMID:18817731, GO:0018105=GO_REF:0000019, GO:0048169=PMID:18817731, GO:0050885=GO_REF:0000019, GO:0051924=PMID:15294044, GO:0006816=GO_REF:0000019, GO:0004683=GO_REF:0000003, GO:0060998=PMID:18817731, GO:0061003=GO_REF:0000024, GO:0060333=Reactome:REACT_25078, GO:0005815=GO_REF:0000039, GO:0033017=GO_REF:0000039, GO:0014733=PMID:15294044, GO:0003779=GO_REF:0000037, GO:0002030=GO_REF:0000019, GO:0005524=GO_REF:0000037, GO:0030666=Reactome:REACT_18393, GO:0032222=GO_REF:0000019, GO:0007165=PMID:9060999, GO:0004672=GO_REF:0000002, GO:0004674=GO_REF:0000038, GO:0010976=GO_REF:0000024, GO:0005654=Reactome:REACT_20634, GO:0006468=PMID:9060999, GO:0060466=GO_REF:0000019, GO:0046686=GO_REF:0000019} Q13554 Calcium/calmodulin-dependent protein kinase type II subunit beta protein 20130228 {GO:0005516=IEA, GO:0090129=ISS, GO:0005886=TAS, GO:0019221=TAS, GO:2001235=IEA, GO:0007268=TAS, GO:0051233=IEA, GO:0005829=TAS, GO:0000082=IEA, GO:0051823=TAS, GO:0046777=IDA, GO:0018105=IEA, GO:0048169=TAS, GO:0050885=IEA, GO:0051924=TAS, GO:0006816=IEA, GO:0004683=IEA, GO:0060998=TAS, GO:0061003=ISS, GO:0060333=TAS, GO:0005815=IEA, GO:0033017=IEA, GO:0014733=TAS, GO:0003779=IEA, GO:0002030=IEA, GO:0005524=IEA, GO:0030666=TAS, GO:0032222=IEA, GO:0007165=TAS, GO:0004672=IEA, GO:0004674=IEA, GO:0010976=ISS, GO:0005654=TAS, GO:0006468=TAS, GO:0060466=IEA, GO:0046686=IEA} G1/S transition of mitotic cell cycle, activation of meiosis involved in egg activation, calcium ion transport, cytokine-mediated signaling pathway, inhibitory G-protein coupled receptor phosphorylation, interferon-gamma-mediated signaling pathway, neuromuscular process controlling balance, peptidyl-serine phosphorylation, positive regulation of apoptotic signaling pathway, positive regulation of dendritic spine morphogenesis, positive regulation of neuron projection development, positive regulation of synapse maturation, protein autophosphorylation, protein phosphorylation, regulation of calcium ion transport, regulation of dendritic spine development, regulation of long-term neuronal synaptic plasticity, regulation of skeletal muscle adaptation, regulation of synapse structural plasticity, regulation of synaptic transmission, cholinergic, response to cadmium ion, signal transduction, synaptic transmission cytosol, endocytic vesicle membrane, microtubule organizing center, nucleoplasm, plasma membrane, sarcoplasmic reticulum membrane, spindle midzone ATP binding, actin binding, calmodulin binding, calmodulin-dependent protein kinase activity, protein kinase activity, protein serine/threonine kinase activity Human CAMK2D Reactome UniProtKB {GO:0005516=GO_REF:0000037, GO:0031594=GO_REF:0000019, GO:0005886=Reactome:REACT_20670, GO:0019221=Reactome:REACT_25229, GO:0008016=PMID:17157285, GO:0007268=Reactome:REACT_13685, GO:0060048=GO_REF:0000019, GO:0001558=PMID:9060999, GO:0005829=Reactome:REACT_25369, GO:0043194=GO_REF:0000019, GO:0000082=GO_REF:0000019, GO:0046777=GO_REF:0000019, GO:0018105=GO_REF:0000019, GO:0014704=GO_REF:0000019, GO:0060314=PMID:19482609, GO:0043025=GO_REF:0000019, GO:0006816=GO_REF:0000019, GO:0004683=GO_REF:0000003, GO:0010613=PMID:17179159, GO:0060333=Reactome:REACT_25078, GO:0005954=PMID:11264466, GO:0030315=GO_REF:0000019, GO:0033017=GO_REF:0000039, GO:0010881=PMID:17157285, GO:0005524=GO_REF:0000029, GO:0030666=Reactome:REACT_18393, GO:0002028=GO_REF:0000019, GO:0006468=PMID:17179159, GO:0005654=Reactome:REACT_20634, GO:0060341=PMID:17179159} Q13557 Calcium/calmodulin-dependent protein kinase type II subunit delta protein 20130228 {GO:0005516=IEA, GO:0031594=IEA, GO:0005886=TAS, GO:0019221=TAS, GO:0008016=TAS, GO:0007268=TAS, GO:0060048=IEA, GO:0001558=NAS, GO:0005829=TAS, GO:0043194=IEA, GO:0000082=IEA, GO:0046777=IEA, GO:0018105=IEA, GO:0014704=IEA, GO:0060314=TAS, GO:0043025=IEA, GO:0006816=IEA, GO:0004683=IEA, GO:0010613=IMP, GO:0060333=TAS, GO:0005954=TAS, GO:0030315=IEA, GO:0033017=IEA, GO:0010881=TAS, GO:0005524=NAS, GO:0030666=TAS, GO:0002028=IEA, GO:0006468=IDA, GO:0005654=TAS, GO:0060341=IMP} G1/S transition of mitotic cell cycle, calcium ion transport, cardiac muscle contraction, cytokine-mediated signaling pathway, interferon-gamma-mediated signaling pathway, peptidyl-serine phosphorylation, positive regulation of cardiac muscle hypertrophy, protein autophosphorylation, protein phosphorylation, regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion, regulation of cell growth, regulation of cellular localization, regulation of heart contraction, regulation of ryanodine-sensitive calcium-release channel activity, regulation of sodium ion transport, synaptic transmission T-tubule, axon initial segment, calcium- and calmodulin-dependent protein kinase complex, cytosol, endocytic vesicle membrane, intercalated disc, neuromuscular junction, neuronal cell body, nucleoplasm, plasma membrane, sarcoplasmic reticulum membrane ATP binding, calmodulin binding, calmodulin-dependent protein kinase activity Human CAMK2G UniProtKB UniProtKB {GO:0005515=PMID:22939624, GO:0005516=GO_REF:0000002, GO:0005886=Reactome:REACT_20670, GO:0019221=Reactome:REACT_25229, GO:0007268=Reactome:REACT_13685, GO:0014733=PMID:15294044, GO:0033017=GO_REF:0000039, GO:0005524=GO_REF:0000038, GO:0030154=GO_REF:0000037, GO:0005829=Reactome:REACT_25369, GO:0007399=GO_REF:0000037, GO:0030666=Reactome:REACT_18393, GO:0000082=GO_REF:0000019, GO:0004672=GO_REF:0000002, GO:0046777=GO_REF:0000019, GO:0051924=PMID:15294044, GO:0004723=PMID:9060999, GO:0005654=Reactome:REACT_20634, GO:0006816=GO_REF:0000019, GO:0006468=GO_REF:0000029, GO:0004683=GO_REF:0000002, GO:0030073=PMID:9240463, GO:0060333=Reactome:REACT_25078, GO:0005954=PMID:11264466} Q8WU40 CAMK2G protein protein 20130413 {GO:0005515=IPI, GO:0005516=IEA, GO:0005886=TAS, GO:0019221=TAS, GO:0007268=TAS, GO:0014733=TAS, GO:0033017=IEA, GO:0005524=IEA, GO:0030154=IEA, GO:0005829=TAS, GO:0007399=IEA, GO:0030666=TAS, GO:0000082=IEA, GO:0004672=IEA, GO:0046777=IEA, GO:0051924=TAS, GO:0004723=NAS, GO:0005654=TAS, GO:0006816=IEA, GO:0006468=NAS, GO:0004683=IEA, GO:0030073=NAS, GO:0060333=TAS, GO:0005954=TAS} G1/S transition of mitotic cell cycle, calcium ion transport, cell differentiation, cytokine-mediated signaling pathway, insulin secretion, interferon-gamma-mediated signaling pathway, nervous system development, protein autophosphorylation, protein phosphorylation, regulation of calcium ion transport, regulation of skeletal muscle adaptation, synaptic transmission calcium- and calmodulin-dependent protein kinase complex, cytosol, endocytic vesicle membrane, nucleoplasm, plasma membrane, sarcoplasmic reticulum membrane ATP binding, calcium-dependent protein serine/threonine phosphatase activity, calmodulin binding, calmodulin-dependent protein kinase activity, protein binding, protein kinase activity Human UniProtKB-KW:KW-0067 CAMK2N1 UniProtKB UniProtKB {GO:0030054=GO_REF:0000037, GO:0019901=GO_REF:0000019, GO:0005886=GO_REF:0000037, GO:0045211=GO_REF:0000037, GO:0043025=GO_REF:0000019, GO:0008427=GO_REF:0000019, GO:0014069=GO_REF:0000039} Q7Z7J9 Calcium/calmodulin-dependent protein kinase II inhibitor 1 protein 20130413 {GO:0030054=IEA, GO:0019901=IEA, GO:0005886=IEA, GO:0045211=IEA, GO:0043025=IEA, GO:0008427=IEA, GO:0014069=IEA} cell junction, neuronal cell body, plasma membrane, postsynaptic density, postsynaptic membrane calcium-dependent protein kinase inhibitor activity, protein kinase binding Human UniProtKB-SubCell:SL-0297 CAMK2N2 UniProtKB UniProtKB {GO:0019901=GO_REF:0000019, GO:0008427=GO_REF:0000019, GO:0005634=GO_REF:0000039, GO:0005829=GO_REF:0000039} Q96S95 Calcium/calmodulin-dependent protein kinase II inhibitor 2 protein 20130413 {GO:0019901=IEA, GO:0008427=IEA, GO:0005634=IEA, GO:0005829=IEA} cytosol, nucleus calcium-dependent protein kinase inhibitor activity, protein kinase binding Human UniProtKB-SubCell:SL-0091 CAMK4 HPA UniProtKB {GO:0005516=GO_REF:0000037, GO:0033081=PMID:18930438, GO:0007268=Reactome:REACT_13685, GO:0005634=GO_REF:0000052, GO:0007202=Reactome:REACT_12079, GO:0005829=Reactome:REACT_15332, GO:0046827=GO_REF:0000019, GO:0005737=GO_REF:0000019, GO:0006954=GO_REF:0000037, GO:0007173=Reactome:REACT_9417, GO:0043011=PMID:17909078, GO:0004683=GO_REF:0000003, GO:0048011=Reactome:REACT_11061, GO:0007616=PMID:18829949, GO:0005730=GO_REF:0000052, GO:0045670=PMID:18930438, GO:0005524=GO_REF:0000037, GO:0007270=GO_REF:0000019, GO:0006913=GO_REF:0000019, GO:0007165=Reactome:REACT_12478, GO:0004672=GO_REF:0000002, GO:0008543=Reactome:REACT_9470, GO:0045087=Reactome:REACT_6802, GO:0006468=PMID:8089075, GO:0005654=Reactome:REACT_20666, GO:0002372=PMID:17909078, GO:0045893=PMID:8855261} Q16566 Calcium/calmodulin-dependent protein kinase type IV protein 20120912 {GO:0005516=IEA, GO:0033081=TAS, GO:0007268=TAS, GO:0005634=IDA, GO:0007202=TAS, GO:0005829=TAS, GO:0046827=IEA, GO:0005737=IEA, GO:0006954=IEA, GO:0007173=TAS, GO:0043011=IMP, GO:0004683=IEA, GO:0048011=TAS, GO:0007616=IGI, GO:0005730=IDA, GO:0045670=TAS, GO:0005524=IEA, GO:0007270=IEA, GO:0006913=IEA, GO:0007165=TAS, GO:0004672=IEA, GO:0008543=TAS, GO:0045087=TAS, GO:0006468=TAS, GO:0005654=TAS, GO:0002372=IMP, GO:0045893=IDA} activation of phospholipase C activity, epidermal growth factor receptor signaling pathway, fibroblast growth factor receptor signaling pathway, inflammatory response, innate immune response, long-term memory, myeloid dendritic cell cytokine production, myeloid dendritic cell differentiation, neuron-neuron synaptic transmission, neurotrophin TRK receptor signaling pathway, nucleocytoplasmic transport, positive regulation of protein export from nucleus, positive regulation of transcription, DNA-dependent, protein phosphorylation, regulation of T cell differentiation in thymus, regulation of osteoclast differentiation, signal transduction, synaptic transmission cytoplasm, cytosol, nucleolus, nucleoplasm, nucleus ATP binding, calmodulin binding, calmodulin-dependent protein kinase activity, protein kinase activity NOT Human CAMKK1 Reactome UniProtKB {GO:0005516=GO_REF:0000037, GO:0004674=GO_REF:0000038, GO:0007268=Reactome:REACT_13685, GO:0005634=GO_REF:0000039, GO:0004683=GO_REF:0000003, GO:0005524=GO_REF:0000037, GO:0005829=Reactome:REACT_20635} Q8N5S9 Calcium/calmodulin-dependent protein kinase kinase 1 protein 20130301 {GO:0005516=IEA, GO:0004674=IEA, GO:0007268=TAS, GO:0005634=IEA, GO:0004683=IEA, GO:0005524=IEA, GO:0005829=TAS} synaptic transmission cytosol, nucleus ATP binding, calmodulin binding, calmodulin-dependent protein kinase activity, protein serine/threonine kinase activity Human CAMKK2 HPA UniProtKB {GO:0045859=PMID:11395482, GO:0005516=PMID:11395482, GO:0019722=PMID:11395482, GO:0005509=PMID:11395482, GO:0005634=GO_REF:0000039, GO:0042995=GO_REF:0000039, GO:0005524=GO_REF:0000037, GO:0005622=PMID:11395482, GO:0005737=GO_REF:0000052, GO:0004672=GO_REF:0000002, GO:0046777=PMID:11395482, GO:0000165=PMID:11395482, GO:0004674=GO_REF:0000038, GO:0006468=PMID:11395482, GO:0004713=PMID:11395482, GO:0004683=GO_REF:0000003, GO:0045893=PMID:11395482} Q96RR4 Calcium/calmodulin-dependent protein kinase kinase 2 protein 20090616 {GO:0045859=TAS, GO:0005516=TAS, GO:0019722=TAS, GO:0005509=IDA, GO:0005634=IEA, GO:0042995=IEA, GO:0005524=IEA, GO:0005622=TAS, GO:0005737=IDA, GO:0004672=IEA, GO:0046777=IDA, GO:0000165=TAS, GO:0004674=IEA, GO:0006468=IDA, GO:0004713=TAS, GO:0004683=IEA, GO:0045893=TAS} MAPK cascade, calcium-mediated signaling, positive regulation of transcription, DNA-dependent, protein autophosphorylation, protein phosphorylation, regulation of protein kinase activity cell projection, cytoplasm, intracellular, nucleus ATP binding, calcium ion binding, calmodulin binding, calmodulin-dependent protein kinase activity, protein kinase activity, protein serine/threonine kinase activity, protein tyrosine kinase activity Human CAMKMT UniProtKB UniProtKB {GO:0005737=GO_REF:0000039, GO:0018025=GO_REF:0000003} Q7Z624 Calmodulin-lysine N-methyltransferase protein 20130413 {GO:0005737=IEA, GO:0018025=IEA} cytoplasm calmodulin-lysine N-methyltransferase activity Human UniProtKB-SubCell:SL-0086 CAMKV UniProtKB UniProtKB {GO:0005516=GO_REF:0000037, GO:0004672=GO_REF:0000002, GO:0005886=GO_REF:0000039, GO:0005524=GO_REF:0000002, GO:0030659=GO_REF:0000039} Q8NCB2 CaM kinase-like vesicle-associated protein protein 20130413 {GO:0005516=IEA, GO:0004672=IEA, GO:0005886=IEA, GO:0005524=IEA, GO:0030659=IEA} cytoplasmic vesicle membrane, plasma membrane ATP binding, calmodulin binding, protein kinase activity Human UniProtKB-SubCell:SL-0089 CAMLG IntAct UniProtKB {GO:0005515=PMID:15451437, GO:0007165=PMID:7522304, GO:0007173=GO_REF:0000019, GO:0001881=GO_REF:0000019, GO:0005783=PMID:12919676, GO:0006952=PMID:7522304, GO:0016021=GO_REF:0000037} P49069 Calcium signal-modulating cyclophilin ligand protein 20130415 {GO:0005515=IPI, GO:0007165=TAS, GO:0007173=IEA, GO:0001881=IEA, GO:0005783=IDA, GO:0006952=TAS, GO:0016021=IEA} defense response, epidermal growth factor receptor signaling pathway, receptor recycling, signal transduction endoplasmic reticulum, integral to membrane protein binding Human UniProtKB:P46695 CAMP Reactome UniProtKB {GO:0050829=GO_REF:0000019, GO:0051873=PMID:16177355, GO:0051701=Reactome:REACT_121237, GO:0050830=GO_REF:0000019, GO:0005618=Reactome:REACT_121346, GO:0042581=GO_REF:0000019, GO:0005576=GO_REF:0000039, GO:0044130=GO_REF:0000019, GO:0090382=Reactome:REACT_121256, GO:0044140=PMID:16177355, GO:0042742=PMID:8681941, GO:0005829=Reactome:REACT_121346} P49913 Cathelicidin antimicrobial peptide protein 20130301 {GO:0050829=IEA, GO:0051873=IDA, GO:0051701=TAS, GO:0050830=IEA, GO:0005618=TAS, GO:0042581=IEA, GO:0005576=IEA, GO:0044130=IEA, GO:0090382=TAS, GO:0044140=IDA, GO:0042742=TAS, GO:0005829=TAS} defense response to Gram-negative bacterium, defense response to Gram-positive bacterium, defense response to bacterium, interaction with host, killing by host of symbiont cells, negative regulation of growth of symbiont in host, negative regulation of growth of symbiont on or near host surface, phagosome maturation cell wall, cytosol, extracellular region, specific granule Human CAMSAP1 UniProtKB UniProtKB {GO:0008017=GO_REF:0000002, GO:0005737=GO_REF:0000037, GO:0022604=PMID:21834987, GO:0007010=PMID:21834987, GO:0005874=GO_REF:0000037} Q5T5Y3 Calmodulin-regulated spectrin-associated protein 1 protein 20110926 {GO:0008017=IEA, GO:0005737=IEA, GO:0022604=IMP, GO:0007010=IMP, GO:0005874=IEA} cytoskeleton organization, regulation of cell morphogenesis cytoplasm, microtubule microtubule binding Human CAMSAP2 IntAct UniProtKB {GO:0005515=PMID:20195357, GO:0008017=GO_REF:0000002, GO:0005737=GO_REF:0000037, GO:0005874=GO_REF:0000037} Q08AD1 Calmodulin-regulated spectrin-associated protein 2 protein 20130415 {GO:0005515=IPI, GO:0008017=IEA, GO:0005737=IEA, GO:0005874=IEA} cytoplasm, microtubule microtubule binding, protein binding Human UniProtKB:P29692 CAMSAP3 UniProtKB UniProtKB {GO:0070507=PMID:19041755, GO:0090136=PMID:19041755, GO:0005915=PMID:19041755, GO:0005737=PMID:19041755, GO:0034453=PMID:19041755, GO:0010923=PMID:19389623, GO:0051011=PMID:19041755, GO:0005874=GO_REF:0000037, GO:0045218=PMID:19041755} Q9P1Y5 Calmodulin-regulated spectrin-associated protein 3 protein 20111103 {GO:0070507=IMP, GO:0090136=IMP, GO:0005915=IDA, GO:0005737=IDA, GO:0034453=IMP, GO:0010923=IDA, GO:0051011=IDA, GO:0005874=IEA, GO:0045218=IMP} epithelial cell-cell adhesion, microtubule anchoring, negative regulation of phosphatase activity, regulation of microtubule cytoskeleton organization, zonula adherens maintenance cytoplasm, microtubule, zonula adherens microtubule minus-end binding Human CAMTA1 HPA UniProtKB {GO:0005737=GO_REF:0000052, GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000052, GO:0003677=GO_REF:0000002, GO:0006351=GO_REF:0000037} Q9Y6Y1 Calmodulin-binding transcription activator 1 protein 20110516 {GO:0005737=IDA, GO:0006355=IEA, GO:0005634=IDA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent cytoplasm, nucleus DNA binding Human CAMTA2 IntAct UniProtKB {GO:0005515=PMID:16678093, GO:0042826=PMID:16678093, GO:0006357=PMID:16678093, GO:0045944=PMID:16678093, GO:0003682=PMID:16678093, GO:0014898=PMID:16678093, GO:0005634=PMID:16678093, GO:0003677=GO_REF:0000002, GO:0006351=GO_REF:0000037, GO:0008134=PMID:16678093} O94983 Calmodulin-binding transcription activator 2 protein 20130415 {GO:0005515=IPI, GO:0042826=IDA, GO:0006357=IDA, GO:0045944=IGI, GO:0003682=IDA, GO:0014898=IDA, GO:0005634=IDA, GO:0003677=IEA, GO:0006351=IEA, GO:0008134=IGI} cardiac muscle hypertrophy in response to stress, positive regulation of transcription from RNA polymerase II promoter, regulation of transcription from RNA polymerase II promoter, transcription, DNA-dependent nucleus DNA binding, chromatin binding, histone deacetylase binding, protein binding, transcription factor binding Human UniProtKB:P42582 CAND1 MGI UniProtKB {GO:0005515=PMID:18826954, GO:0031461=PMID:22405651, GO:0005737=PMID:21249194, GO:0016567=PMID:21249194, GO:0045899=GO_REF:0000019, GO:0000151=PMID:12609982, GO:0017025=GO_REF:0000019, GO:0005634=PMID:21249194, GO:0010265=PMID:21249194, GO:0043086=PMID:12609982, GO:0030154=PMID:10581176} Q86VP6 Cullin-associated NEDD8-dissociated protein 1 protein 20121116 {GO:0005515=IPI, GO:0031461=IDA, GO:0005737=IDA, GO:0016567=IDA, GO:0045899=IEA, GO:0000151=IDA, GO:0017025=IEA, GO:0005634=IDA, GO:0010265=IDA, GO:0043086=IDA, GO:0030154=IDA} SCF complex assembly, cell differentiation, negative regulation of catalytic activity, positive regulation of RNA polymerase II transcriptional preinitiation complex assembly, protein ubiquitination cullin-RING ubiquitin ligase complex, cytoplasm, nucleus, ubiquitin ligase complex TBP-class protein binding, protein binding Human CAND2 UniProtKB UniProtKB {GO:0005515=PMID:12692129, GO:0005622=PMID:12692129, GO:0017025=GO_REF:0000019, GO:0005634=GO_REF:0000039, GO:0045893=GO_REF:0000024, GO:0006351=GO_REF:0000037} O75155 Cullin-associated NEDD8-dissociated protein 2 protein 20040420 {GO:0005515=IPI, GO:0005622=IDA, GO:0017025=IEA, GO:0005634=IEA, GO:0045893=ISS, GO:0006351=IEA} positive regulation of transcription, DNA-dependent, transcription, DNA-dependent intracellular, nucleus TBP-class protein binding, protein binding Human UniProtKB:Q15386 CANT1 GOC UniProtKB {GO:0007165=PMID:12761501, GO:0016462=GO_REF:0000002, GO:0032580=GO_REF:0000039, GO:0045134=GO_REF:0000003, GO:0005509=GO_REF:0000002, GO:0005789=GO_REF:0000039, GO:0004871=PMID:12761501, GO:0016021=GO_REF:0000037, GO:0043123=PMID:12761501, GO:0030166=PMID:22539336} Q8WVQ1 Soluble calcium-activated nucleotidase 1 protein 20130413 {GO:0007165=IMP, GO:0016462=IEA, GO:0032580=IEA, GO:0045134=IEA, GO:0005509=IEA, GO:0005789=IEA, GO:0004871=IMP, GO:0016021=IEA, GO:0043123=IMP, GO:0030166=IMP} positive regulation of I-kappaB kinase/NF-kappaB cascade, proteoglycan biosynthetic process, signal transduction Golgi cisterna membrane, endoplasmic reticulum membrane, integral to membrane calcium ion binding, pyrophosphatase activity, signal transducer activity, uridine-diphosphatase activity Human CANX HPA UniProtKB {GO:0072583=GO_REF:0000024, GO:0005515=PMID:17220478, GO:0030424=GO_REF:0000019, GO:0002474=Reactome:REACT_75820, GO:0009306=PMID:8055875, GO:0005783=GO_REF:0000052, GO:0032839=GO_REF:0000019, GO:0019886=Reactome:REACT_121399, GO:0043197=GO_REF:0000019, GO:0006457=Reactome:REACT_23878, GO:0043025=GO_REF:0000019, GO:0071556=Reactome:REACT_75898, GO:0018279=Reactome:REACT_22426, GO:0042470=GO_REF:0000039, GO:0007568=GO_REF:0000019, GO:0005509=GO_REF:0000002, GO:0048488=GO_REF:0000024, GO:0035255=GO_REF:0000019, GO:0005789=PMID:19723497, GO:0005840=GO_REF:0000019, GO:0005788=Reactome:REACT_121334, GO:0051082=GO_REF:0000029, GO:0034185=GO_REF:0000019, GO:0016021=GO_REF:0000019, GO:0044267=Reactome:REACT_17015, GO:0043687=Reactome:REACT_22161} P27824 Calnexin protein 20080205 {GO:0072583=ISS, GO:0005515=IPI, GO:0030424=IEA, GO:0002474=TAS, GO:0009306=TAS, GO:0005783=IDA, GO:0032839=IEA, GO:0019886=TAS, GO:0043197=IEA, GO:0006457=TAS, GO:0043025=IEA, GO:0071556=TAS, GO:0018279=TAS, GO:0042470=IEA, GO:0007568=IEA, GO:0005509=IEA, GO:0048488=ISS, GO:0035255=IEA, GO:0005789=IDA, GO:0005840=IEA, GO:0005788=TAS, GO:0051082=NAS, GO:0034185=IEA, GO:0016021=IEA, GO:0044267=TAS, GO:0043687=TAS} aging, antigen processing and presentation of exogenous peptide antigen via MHC class II, antigen processing and presentation of peptide antigen via MHC class I, cellular protein metabolic process, clathrin-mediated endocytosis, post-translational protein modification, protein N-linked glycosylation via asparagine, protein folding, protein secretion, synaptic vesicle endocytosis axon, dendrite cytoplasm, dendritic spine, endoplasmic reticulum, endoplasmic reticulum lumen, endoplasmic reticulum membrane, integral to lumenal side of endoplasmic reticulum membrane, integral to membrane, melanosome, neuronal cell body, ribosome apolipoprotein binding, calcium ion binding, ionotropic glutamate receptor binding, protein binding, unfolded protein binding Human CAP1 InterPro UniProtKB {GO:0030036=GO_REF:0000019, GO:0005886=GO_REF:0000039, GO:0001667=GO_REF:0000019, GO:0030168=Reactome:REACT_798, GO:0003779=GO_REF:0000002, GO:0006898=GO_REF:0000019, GO:0000902=GO_REF:0000019, GO:0007190=PMID:7962207, GO:0007165=PMID:1406678, GO:0007163=PMID:1406678, GO:0007411=Reactome:REACT_18266, GO:0007596=Reactome:REACT_604, GO:0007010=GO_REF:0000002, GO:0002576=Reactome:REACT_318, GO:0030864=GO_REF:0000019} Q5T0S3 Adenylyl cyclase-associated protein 1 protein 20130413 {GO:0030036=IEA, GO:0005886=IEA, GO:0001667=IEA, GO:0030168=TAS, GO:0003779=IEA, GO:0006898=IEA, GO:0000902=IEA, GO:0007190=TAS, GO:0007165=TAS, GO:0007163=TAS, GO:0007411=TAS, GO:0007596=TAS, GO:0007010=IEA, GO:0002576=TAS, GO:0030864=IEA} actin cytoskeleton organization, activation of adenylate cyclase activity, ameboidal cell migration, axon guidance, blood coagulation, cell morphogenesis, cytoskeleton organization, establishment or maintenance of cell polarity, platelet activation, platelet degranulation, receptor-mediated endocytosis, signal transduction cortical actin cytoskeleton, plasma membrane actin binding Human InterPro:IPR001837|InterPro:IPR013992|InterPro:IPR018106 CAP2 Reactome UniProtKB {GO:0007190=PMID:7962207, GO:0007165=PMID:7962207, GO:0000902=GO_REF:0000002, GO:0007163=PMID:7962207, GO:0005886=GO_REF:0000039, GO:0007411=Reactome:REACT_18266, GO:0007010=GO_REF:0000002, GO:0003779=GO_REF:0000002} P40123 Adenylyl cyclase-associated protein 2 protein 20130301 {GO:0007190=TAS, GO:0007165=TAS, GO:0000902=IEA, GO:0007163=TAS, GO:0005886=IEA, GO:0007411=TAS, GO:0007010=IEA, GO:0003779=IEA} activation of adenylate cyclase activity, axon guidance, cell morphogenesis, cytoskeleton organization, establishment or maintenance of cell polarity, signal transduction plasma membrane actin binding Human CAPG HPA UniProtKB {GO:0042470=GO_REF:0000039, GO:0051016=PMID:1322908, GO:0031965=GO_REF:0000052, GO:0005737=GO_REF:0000052, GO:0006461=PMID:1322908, GO:0030031=GO_REF:0000019, GO:0005730=GO_REF:0000052, GO:0008290=PMID:1322908, GO:0005634=GO_REF:0000052, GO:0003779=GO_REF:0000037} P40121 Macrophage-capping protein protein 20101115 {GO:0042470=IEA, GO:0051016=TAS, GO:0031965=IDA, GO:0005737=IDA, GO:0006461=NAS, GO:0030031=IEA, GO:0005730=IDA, GO:0008290=TAS, GO:0005634=IDA, GO:0003779=IEA} barbed-end actin filament capping, cell projection assembly, protein complex assembly F-actin capping protein complex, cytoplasm, melanosome, nuclear membrane, nucleolus, nucleus actin binding Human CAPN1 HPA UniProtKB {GO:0005515=PMID:21988832, GO:0005622=GO_REF:0000002, GO:0005737=GO_REF:0000052, GO:0008284=PMID:8702541, GO:0004198=GO_REF:0000002, GO:0005886=GO_REF:0000039, GO:0032801=GO_REF:0000019, GO:0005509=GO_REF:0000002, GO:0006508=GO_REF:0000037} P07384 Calpain-1 catalytic subunit protein 20080205 {GO:0005515=IPI, GO:0005622=IEA, GO:0005737=IDA, GO:0008284=TAS, GO:0004198=IEA, GO:0005886=IEA, GO:0032801=IEA, GO:0005509=IEA, GO:0006508=IEA} positive regulation of cell proliferation, proteolysis, receptor catabolic process cytoplasm, intracellular, plasma membrane calcium ion binding, calcium-dependent cysteine-type endopeptidase activity, protein binding Human CAPN10 BHF-UCL UniProtKB {GO:0032388=PMID:12974673, GO:0008092=GO_REF:0000024, GO:0032869=PMID:17572128, GO:0043065=PMID:15044459, GO:0031532=PMID:12974673, GO:0005886=GO_REF:0000024, GO:0005623=PMID:17572128, GO:0005829=GO_REF:0000024, GO:0005622=GO_REF:0000002, GO:0004198=PMID:15044459, GO:0046326=PMID:17572128, GO:0000149=GO_REF:0000024, GO:0006508=PMID:15044459, GO:0032024=PMID:15471947} Q9HC96 Calpain-10 protein 20080214 {GO:0032388=ISS, GO:0008092=ISS, GO:0032869=IMP, GO:0043065=IMP, GO:0031532=ISS, GO:0005886=ISS, GO:0005623=IDA, GO:0005829=ISS, GO:0005622=IEA, GO:0004198=IMP, GO:0046326=IMP, GO:0000149=ISS, GO:0006508=IMP, GO:0032024=IMP} actin cytoskeleton reorganization, cellular response to insulin stimulus, positive regulation of apoptotic process, positive regulation of glucose import, positive regulation of insulin secretion, positive regulation of intracellular transport, proteolysis cell, cytosol, intracellular, plasma membrane SNARE binding, calcium-dependent cysteine-type endopeptidase activity, cytoskeletal protein binding Human CAPN11 PINC UniProtKB {GO:0005622=GO_REF:0000002, GO:0004198=GO_REF:0000002, GO:0001669=GO_REF:0000039, GO:0005509=GO_REF:0000002, GO:0006508=GO_REF:0000037, GO:0008233=PMID:10409436} Q9UMQ6 Calpain-11 protein 20030904 {GO:0005622=IEA, GO:0004198=IEA, GO:0001669=IEA, GO:0005509=IEA, GO:0006508=IEA, GO:0008233=TAS} proteolysis acrosomal vesicle, intracellular calcium ion binding, calcium-dependent cysteine-type endopeptidase activity, peptidase activity Human CAPN2 IntAct UniProtKB {GO:0005515=PMID:10639123, GO:0008092=GO_REF:0000019, GO:0001666=GO_REF:0000019, GO:0016540=GO_REF:0000019, GO:0005886=GO_REF:0000039, GO:0046982=GO_REF:0000019, GO:0001824=GO_REF:0000019, GO:0005509=GO_REF:0000019, GO:0005634=GO_REF:0000019, GO:0007520=GO_REF:0000019, GO:0005622=GO_REF:0000002, GO:0005737=GO_REF:0000039, GO:0004198=GO_REF:0000019, GO:0006508=GO_REF:0000037, GO:0008234=PMID:2209092, GO:0000785=GO_REF:0000019} P17655 Calpain-2 catalytic subunit protein 20130415 {GO:0005515=IPI, GO:0008092=IEA, GO:0001666=IEA, GO:0016540=IEA, GO:0005886=IEA, GO:0046982=IEA, GO:0001824=IEA, GO:0005509=IEA, GO:0005634=IEA, GO:0007520=IEA, GO:0005622=IEA, GO:0005737=IEA, GO:0004198=IEA, GO:0006508=IEA, GO:0008234=TAS, GO:0000785=IEA} blastocyst development, myoblast fusion, protein autoprocessing, proteolysis, response to hypoxia chromatin, cytoplasm, intracellular, nucleus, plasma membrane calcium ion binding, calcium-dependent cysteine-type endopeptidase activity, cysteine-type peptidase activity, cytoskeletal protein binding, protein binding, protein heterodimerization activity Human UniProtKB:P04632 CAPN3 GOC UniProtKB {GO:0030018=GO_REF:0000024, GO:0005886=GO_REF:0000024, GO:0005634=PMID:19386580, GO:0030016=GO_REF:0000024, GO:0003824=PMID:9642272, GO:0031402=GO_REF:0000024, GO:0046716=PMID:19386580, GO:0005829=GO_REF:0000024, GO:0045661=GO_REF:0000019, GO:0005622=PMID:9642272, GO:0005737=PMID:19386580, GO:0051092=PMID:18073330, GO:0001896=GO_REF:0000019, GO:0030239=GO_REF:0000024, GO:0006508=PMID:19386580, GO:0071277=GO_REF:0000024, GO:0004871=PMID:7720071, GO:0033234=PMID:20694146, GO:0008307=GO_REF:0000024, GO:0043122=PMID:18073330, GO:0051281=GO_REF:0000024, GO:0043066=PMID:18073330, GO:0014850=GO_REF:0000024, GO:0014718=GO_REF:0000024, GO:0005509=GO_REF:0000024, GO:0071472=GO_REF:0000024, GO:0045214=GO_REF:0000024, GO:0030315=GO_REF:0000024, GO:0006915=PMID:19386580, GO:0070315=GO_REF:0000019, GO:0072657=GO_REF:0000024, GO:0061061=GO_REF:0000024, GO:0045862=GO_REF:0000024, GO:0031432=PMID:18310072, GO:0007165=PMID:7720071, GO:0051592=GO_REF:0000024, GO:0043234=GO_REF:0000024, GO:0050790=PMID:20694146, GO:0032947=GO_REF:0000024, GO:0007517=PMID:9642272, GO:0006461=GO_REF:0000024, GO:0004198=GO_REF:0000024, GO:0008233=PMID:9642272, GO:0008234=PMID:2555341, GO:0045893=GO_REF:0000019, GO:0045892=GO_REF:0000024} P20807 Calpain-3 protein 20130413 {GO:0030018=ISS, GO:0005886=ISS, GO:0005634=IDA, GO:0030016=ISS, GO:0003824=IDA, GO:0031402=ISS, GO:0046716=TAS, GO:0005829=ISS, GO:0045661=IEA, GO:0005622=TAS, GO:0005737=IDA, GO:0051092=IMP, GO:0001896=IEA, GO:0030239=ISS, GO:0006508=IDA, GO:0071277=ISS, GO:0004871=TAS, GO:0033234=IDA, GO:0008307=ISS, GO:0043122=IMP, GO:0051281=ISS, GO:0043066=IMP, GO:0014850=ISS, GO:0014718=ISS, GO:0005509=ISS, GO:0071472=ISS, GO:0045214=ISS, GO:0030315=ISS, GO:0006915=TAS, GO:0070315=IEA, GO:0072657=ISS, GO:0061061=ISS, GO:0045862=ISS, GO:0031432=IPI, GO:0007165=TAS, GO:0051592=ISS, GO:0043234=ISS, GO:0050790=IDA, GO:0032947=ISS, GO:0007517=TAS, GO:0006461=ISS, GO:0004198=ISS, GO:0008233=IDA, GO:0008234=TAS, GO:0045893=IEA, GO:0045892=ISS} G1 to G0 transition involved in cell differentiation, apoptotic process, autolysis, cellular response to calcium ion, cellular response to salt stress, muscle cell homeostasis, muscle organ development, muscle structure development, myofibril assembly, negative regulation of apoptotic process, negative regulation of protein sumoylation, negative regulation of transcription, DNA-dependent, positive regulation of NF-kappaB transcription factor activity, positive regulation of proteolysis, positive regulation of release of sequestered calcium ion into cytosol, positive regulation of satellite cell activation involved in skeletal muscle regeneration, positive regulation of transcription, DNA-dependent, protein complex assembly, protein localization to membrane, proteolysis, regulation of I-kappaB kinase/NF-kappaB cascade, regulation of catalytic activity, regulation of myoblast differentiation, response to calcium ion, response to muscle activity, sarcomere organization, signal transduction T-tubule, Z disc, cytoplasm, cytosol, intracellular, myofibril, nucleus, plasma membrane, protein complex calcium ion binding, calcium-dependent cysteine-type endopeptidase activity, catalytic activity, cysteine-type peptidase activity, peptidase activity, protein complex scaffold, signal transducer activity, sodium ion binding, structural constituent of muscle, titin binding Human CAPN5 UniProtKB UniProtKB {GO:0005622=GO_REF:0000002, GO:0007165=PMID:9339374, GO:0004198=GO_REF:0000002, GO:0009986=PMID:23055945, GO:0006508=GO_REF:0000037} O15484 Calpain-5 protein 20130318 {GO:0005622=IEA, GO:0007165=TAS, GO:0004198=IEA, GO:0009986=IDA, GO:0006508=IEA} proteolysis, signal transduction cell surface, intracellular calcium-dependent cysteine-type endopeptidase activity Human CAPN6 UniProtKB UniProtKB {GO:0008017=GO_REF:0000024, GO:0048471=PMID:17210638, GO:0004198=GO_REF:0000002, GO:0051493=GO_REF:0000024, GO:0001578=GO_REF:0000024, GO:0005874=GO_REF:0000019, GO:0006508=GO_REF:0000002, GO:0005876=PMID:17210638} Q9Y6Q1 Calpain-6 protein 20110321 {GO:0008017=ISS, GO:0048471=IDA, GO:0004198=IEA, GO:0051493=ISS, GO:0001578=ISS, GO:0005874=IEA, GO:0006508=IEA, GO:0005876=IDA} microtubule bundle formation, proteolysis, regulation of cytoskeleton organization microtubule, perinuclear region of cytoplasm, spindle microtubule calcium-dependent cysteine-type endopeptidase activity, microtubule binding Human UniProtKB:O35646 CAPN7 UniProtKB UniProtKB {GO:0005622=GO_REF:0000002, GO:0090541=PMID:20849418, GO:0004198=GO_REF:0000002, GO:0097264=PMID:20849418, GO:0006508=GO_REF:0000002, GO:0005634=GO_REF:0000039} Q9Y6W3 Calpain-7 protein 20130215 {GO:0005622=IEA, GO:0090541=IPI, GO:0004198=IEA, GO:0097264=IDA, GO:0006508=IEA, GO:0005634=IEA} proteolysis, self proteolysis intracellular, nucleus MIT domain binding, calcium-dependent cysteine-type endopeptidase activity Human CAPNS1 IntAct UniProtKB {GO:0005515=PMID:10639123, GO:0008284=PMID:8702541, GO:0005737=GO_REF:0000039, GO:0004198=GO_REF:0000019, GO:0005886=GO_REF:0000039, GO:0005509=GO_REF:0000002} P04632 Calpain small subunit 1 protein 20130415 {GO:0005515=IPI, GO:0008284=TAS, GO:0005737=IEA, GO:0004198=IEA, GO:0005886=IEA, GO:0005509=IEA} positive regulation of cell proliferation cytoplasm, plasma membrane calcium ion binding, calcium-dependent cysteine-type endopeptidase activity, protein binding Human UniProtKB:P17655 CAPNS2 UniProtKB UniProtKB {GO:0005737=GO_REF:0000039, GO:0005886=GO_REF:0000039, GO:0005509=GO_REF:0000002} Q96L46 Calpain small subunit 2 protein 20130413 {GO:0005737=IEA, GO:0005886=IEA, GO:0005509=IEA} cytoplasm, plasma membrane calcium ion binding Human UniProtKB-SubCell:SL-0039 CAPRIN1 HPA UniProtKB {GO:0017148=GO_REF:0000024, GO:0005737=GO_REF:0000052, GO:0005887=PMID:7657653, GO:0010494=GO_REF:0000024, GO:0000932=GO_REF:0000024, GO:0050775=GO_REF:0000024, GO:0003723=GO_REF:0000024, GO:0030425=GO_REF:0000039, GO:0061003=GO_REF:0000024, GO:0005829=GO_REF:0000039} Q14444 Caprin-1 protein 20100326 {GO:0017148=ISS, GO:0005737=IDA, GO:0005887=TAS, GO:0010494=ISS, GO:0000932=ISS, GO:0050775=ISS, GO:0003723=ISS, GO:0030425=IEA, GO:0061003=ISS, GO:0005829=IEA} negative regulation of translation, positive regulation of dendrite morphogenesis, positive regulation of dendritic spine morphogenesis cytoplasm, cytoplasmic mRNA processing body, cytoplasmic stress granule, cytosol, dendrite, integral to plasma membrane RNA binding Human CAPRIN2 BHF-UCL UniProtKB {GO:0017148=GO_REF:0000037, GO:0030308=PMID:14593112, GO:0003723=GO_REF:0000037, GO:0090263=PMID:18762581, GO:0005102=PMID:18762581, GO:0032092=PMID:18762581, GO:0005739=PMID:14593112, GO:0043235=PMID:18762581, GO:0005737=PMID:14593112, GO:0033138=PMID:18762581, GO:0050775=GO_REF:0000024, GO:0045944=PMID:18762581, GO:0061003=GO_REF:0000024} Q6IMN6 Caprin-2 protein 20110203 {GO:0017148=IEA, GO:0030308=IDA, GO:0003723=IEA, GO:0090263=IDA, GO:0005102=IPI, GO:0032092=IDA, GO:0005739=IDA, GO:0043235=IDA, GO:0005737=IDA, GO:0033138=IDA, GO:0050775=ISS, GO:0045944=IDA, GO:0061003=ISS} negative regulation of cell growth, negative regulation of translation, positive regulation of canonical Wnt receptor signaling pathway, positive regulation of dendrite morphogenesis, positive regulation of dendritic spine morphogenesis, positive regulation of peptidyl-serine phosphorylation, positive regulation of protein binding, positive regulation of transcription from RNA polymerase II promoter cytoplasm, mitochondrion, receptor complex RNA binding, receptor binding Human CAPSL UniProtKB UniProtKB {GO:0005737=GO_REF:0000039, GO:0005509=GO_REF:0000002} Q8WWF8 Calcyphosin-like protein protein 20130413 {GO:0005737=IEA, GO:0005509=IEA} cytoplasm calcium ion binding Human UniProtKB-SubCell:SL-0086 CAPZA1 Reactome UniProtKB {GO:0030036=GO_REF:0000002, GO:0006928=PMID:16130169, GO:0003779=GO_REF:0000037, GO:0005576=Reactome:REACT_25219, GO:0015629=PMID:7665558, GO:0051693=GO_REF:0000037, GO:0005829=Reactome:REACT_25363, GO:0006461=PMID:9331217, GO:0007596=Reactome:REACT_604, GO:0045087=Reactome:REACT_6802, GO:0071203=PMID:19922875, GO:0008290=GO_REF:0000002, GO:0005856=PMID:16130169} P52907 F-actin-capping protein subunit alpha-1 protein 20130301 {GO:0030036=IEA, GO:0006928=TAS, GO:0003779=IEA, GO:0005576=TAS, GO:0015629=TAS, GO:0051693=IEA, GO:0005829=TAS, GO:0006461=TAS, GO:0007596=TAS, GO:0045087=TAS, GO:0071203=IDA, GO:0008290=IEA, GO:0005856=TAS} actin cytoskeleton organization, actin filament capping, blood coagulation, cellular component movement, innate immune response, protein complex assembly F-actin capping protein complex, WASH complex, actin cytoskeleton, cytoskeleton, cytosol, extracellular region actin binding Human CAPZA2 HPA UniProtKB {GO:0030036=GO_REF:0000002, GO:0006928=PMID:9331217, GO:0003779=GO_REF:0000037, GO:0005576=Reactome:REACT_25219, GO:0015629=PMID:9331217, GO:0051693=GO_REF:0000037, GO:0005829=Reactome:REACT_25363, GO:0005737=GO_REF:0000052, GO:0006461=PMID:9331217, GO:0016020=GO_REF:0000019, GO:0007596=Reactome:REACT_604, GO:0045087=Reactome:REACT_6802, GO:0008290=GO_REF:0000002, GO:0030863=GO_REF:0000019} P47755 F-actin-capping protein subunit alpha-2 protein 20080818 {GO:0030036=IEA, GO:0006928=TAS, GO:0003779=IEA, GO:0005576=TAS, GO:0015629=TAS, GO:0051693=IEA, GO:0005829=TAS, GO:0005737=IDA, GO:0006461=TAS, GO:0016020=IEA, GO:0007596=TAS, GO:0045087=TAS, GO:0008290=IEA, GO:0030863=IEA} actin cytoskeleton organization, actin filament capping, blood coagulation, cellular component movement, innate immune response, protein complex assembly F-actin capping protein complex, actin cytoskeleton, cortical cytoskeleton, cytoplasm, cytosol, extracellular region, membrane actin binding Human CAPZA3 ENSEMBL UniProtKB {GO:0030036=GO_REF:0000002, GO:0016020=GO_REF:0000019, GO:0030863=GO_REF:0000019, GO:0003779=GO_REF:0000037, GO:0008290=GO_REF:0000002, GO:0051693=GO_REF:0000037} Q96KX2 F-actin-capping protein subunit alpha-3 protein 20130413 {GO:0030036=IEA, GO:0016020=IEA, GO:0030863=IEA, GO:0003779=IEA, GO:0008290=IEA, GO:0051693=IEA} actin cytoskeleton organization, actin filament capping F-actin capping protein complex, cortical cytoskeleton, membrane actin binding Human Ensembl:ENSMUSP00000038562 CAPZB Reactome UniProtKB {GO:0030036=GO_REF:0000002, GO:0030032=GO_REF:0000019, GO:0006928=PMID:16130169, GO:0003779=GO_REF:0000037, GO:0015629=PMID:7665558, GO:0030027=GO_REF:0000019, GO:0005829=Reactome:REACT_25363, GO:0051693=GO_REF:0000037, GO:0016020=GO_REF:0000019, GO:0007596=Reactome:REACT_604, GO:0007010=PMID:21834987, GO:0022604=PMID:21834987, GO:0071203=PMID:19922875, GO:0008290=GO_REF:0000002, GO:0030863=GO_REF:0000019, GO:0005856=PMID:16130169} P47756 F-actin-capping protein subunit beta protein 20100617 {GO:0030036=IEA, GO:0030032=IEA, GO:0006928=TAS, GO:0003779=IEA, GO:0015629=TAS, GO:0030027=IEA, GO:0005829=TAS, GO:0051693=IEA, GO:0016020=IEA, GO:0007596=TAS, GO:0007010=IMP, GO:0022604=IMP, GO:0071203=IDA, GO:0008290=IEA, GO:0030863=IEA, GO:0005856=TAS} actin cytoskeleton organization, actin filament capping, blood coagulation, cellular component movement, cytoskeleton organization, lamellipodium assembly, regulation of cell morphogenesis F-actin capping protein complex, WASH complex, actin cytoskeleton, cortical cytoskeleton, cytoskeleton, cytosol, lamellipodium, membrane actin binding Human CARD10 UniProtKB UniProtKB {GO:0005515=PMID:11259443, GO:0005737=PMID:11259443, GO:0006461=PMID:11259443, GO:0032449=PMID:15125833, GO:0007250=PMID:11259443, GO:0030159=PMID:11259443, GO:0042981=GO_REF:0000002} Q9BWT7 Caspase recruitment domain-containing protein 10 protein 20061124 {GO:0005515=IPI, GO:0005737=NAS, GO:0006461=NAS, GO:0032449=NAS, GO:0007250=IDA, GO:0030159=NAS, GO:0042981=IEA} activation of NF-kappaB-inducing kinase activity, protein complex assembly, regulation of apoptotic process CBM complex, cytoplasm protein binding, receptor signaling complex scaffold activity Human CARD11 Reactome UniProtKB {GO:0005515=PMID:17287217, GO:0050700=PMID:11278692, GO:0050852=Reactome:REACT_12526, GO:0045577=GO_REF:0000019, GO:0005886=Reactome:REACT_118777, GO:0030890=GO_REF:0000019, GO:0031295=PMID:17287217, GO:0004385=PMID:11278692, GO:0042981=GO_REF:0000002, GO:0001819=PMID:12154360, GO:0005829=Reactome:REACT_118598, GO:0005622=GO_REF:0000002, GO:0007165=GO_REF:0000019, GO:0045086=GO_REF:0000019, GO:0005737=PMID:12154360, GO:0051092=PMID:12154360, GO:0042101=PMID:12154360, GO:0045061=GO_REF:0000019, GO:0042102=GO_REF:0000019, GO:0050776=GO_REF:0000019, GO:0045580=GO_REF:0000019, GO:0045121=PMID:17287217, GO:0043123=GO_REF:0000019} Q9BXL7 Caspase recruitment domain-containing protein 11 protein 20071029 {GO:0005515=IPI, GO:0050700=IPI, GO:0050852=TAS, GO:0045577=IEA, GO:0005886=TAS, GO:0030890=IEA, GO:0031295=IDA, GO:0004385=NAS, GO:0042981=IEA, GO:0001819=IMP, GO:0005829=TAS, GO:0005622=IEA, GO:0007165=IEA, GO:0045086=IEA, GO:0005737=IDA, GO:0051092=IMP, GO:0042101=IDA, GO:0045061=IEA, GO:0042102=IEA, GO:0050776=IEA, GO:0045580=IEA, GO:0045121=IDA, GO:0043123=IEA} T cell costimulation, T cell receptor signaling pathway, positive regulation of B cell proliferation, positive regulation of I-kappaB kinase/NF-kappaB cascade, positive regulation of NF-kappaB transcription factor activity, positive regulation of T cell proliferation, positive regulation of cytokine production, positive regulation of interleukin-2 biosynthetic process, regulation of B cell differentiation, regulation of T cell differentiation, regulation of apoptotic process, regulation of immune response, signal transduction, thymic T cell selection T cell receptor complex, cytoplasm, cytosol, intracellular, membrane raft, plasma membrane CARD domain binding, guanylate kinase activity, protein binding Human CARD14 HPA UniProtKB {GO:0050700=PMID:11278692, GO:0005622=GO_REF:0000002, GO:0005737=GO_REF:0000052, GO:0005886=PMID:11278692, GO:0007250=PMID:11278692, GO:0016235=GO_REF:0000052, GO:0001934=PMID:11278692, GO:0042981=GO_REF:0000002} Q9BXL6 Caspase recruitment domain-containing protein 14 protein 20100326 {GO:0050700=IPI, GO:0005622=IEA, GO:0005737=IDA, GO:0005886=NAS, GO:0007250=NAS, GO:0016235=IDA, GO:0001934=IDA, GO:0042981=IEA} activation of NF-kappaB-inducing kinase activity, positive regulation of protein phosphorylation, regulation of apoptotic process aggresome, cytoplasm, intracellular, plasma membrane CARD domain binding Human CARD16 UniProtKB UniProtKB {GO:0005622=GO_REF:0000002, GO:0004869=GO_REF:0000037, GO:0042981=GO_REF:0000002} Q5EG05 Caspase recruitment domain-containing protein 16 protein 20130413 {GO:0005622=IEA, GO:0004869=IEA, GO:0042981=IEA} regulation of apoptotic process intracellular cysteine-type endopeptidase inhibitor activity Human UniProtKB-KW:KW-0789 CARD17 UniProtKB UniProtKB {GO:0004197=GO_REF:0000002, GO:0005737=GO_REF:0000039, GO:0004869=GO_REF:0000037, GO:0006508=GO_REF:0000002, GO:0042981=GO_REF:0000002} Q5XLA6 Caspase recruitment domain-containing protein 17 protein 20130413 {GO:0004197=IEA, GO:0005737=IEA, GO:0004869=IEA, GO:0006508=IEA, GO:0042981=IEA} proteolysis, regulation of apoptotic process cytoplasm cysteine-type endopeptidase activity, cysteine-type endopeptidase inhibitor activity Human UniProtKB-SubCell:SL-0086 CARD18 UniProtKB UniProtKB {GO:0005622=GO_REF:0000002, GO:0006954=PMID:11051551, GO:0004869=GO_REF:0000037, GO:0042981=GO_REF:0000002, GO:0005575=GO_REF:0000015} P57730 Caspase recruitment domain-containing protein 18 protein 20061026 {GO:0005622=IEA, GO:0006954=NAS, GO:0004869=IEA, GO:0042981=IEA, GO:0005575=ND} inflammatory response, regulation of apoptotic process cellular_component, intracellular cysteine-type endopeptidase inhibitor activity Human CARD6 UniProtKB UniProtKB {GO:0005622=GO_REF:0000002, GO:0006915=GO_REF:0000037, GO:0042981=GO_REF:0000002} Q9BX69 Caspase recruitment domain-containing protein 6 protein 20130413 {GO:0005622=IEA, GO:0006915=IEA, GO:0042981=IEA} apoptotic process, regulation of apoptotic process intracellular Human UniProtKB-KW:KW-0053 CARD8 GOC UniProtKB {GO:0043280=PMID:15030775, GO:0005515=PMID:11551959, GO:0072559=PMID:15030775, GO:0005737=PMID:15030775, GO:0006919=PMID:15030775, GO:0050718=PMID:15030775, GO:0032089=PMID:15030775, GO:0005634=PMID:11551959, GO:0008656=PMID:15030775, GO:0042803=PMID:15030775, GO:0043124=PMID:11551959} Q9Y2G2 Caspase recruitment domain-containing protein 8 protein 20130413 {GO:0043280=IDA, GO:0005515=IPI, GO:0072559=IDA, GO:0005737=IDA, GO:0006919=IDA, GO:0050718=IDA, GO:0032089=IPI, GO:0005634=IDA, GO:0008656=IDA, GO:0042803=IDA, GO:0043124=IDA} activation of cysteine-type endopeptidase activity involved in apoptotic process, negative regulation of I-kappaB kinase/NF-kappaB cascade, positive regulation of cysteine-type endopeptidase activity involved in apoptotic process, positive regulation of interleukin-1 beta secretion NLRP3 inflammasome complex, cytoplasm, nucleus NACHT domain binding, cysteine-type endopeptidase activator activity involved in apoptotic process, protein binding, protein homodimerization activity Human CARD9 Reactome UniProtKB {GO:0050700=PMID:11053425, GO:0032755=GO_REF:0000019, GO:0032760=GO_REF:0000019, GO:0050830=GO_REF:0000019, GO:0042493=GO_REF:0000019, GO:0042534=GO_REF:0000019, GO:0070423=Reactome:REACT_75776, GO:0046330=PMID:17187069, GO:0009620=GO_REF:0000019, GO:0032874=PMID:17187069, GO:0042981=GO_REF:0000002, GO:0045408=GO_REF:0000019, GO:0035872=Reactome:REACT_75913, GO:0042803=PMID:11053425, GO:0005737=PMID:11053425, GO:0051607=GO_REF:0000019, GO:0045076=GO_REF:0000019, GO:0045087=Reactome:REACT_6802, GO:0032494=GO_REF:0000019, GO:0032495=GO_REF:0000019, GO:0043123=PMID:11053425, GO:0043330=GO_REF:0000019} Q9H257 Caspase recruitment domain-containing protein 9 protein 20100330 {GO:0050700=IPI, GO:0032755=IEA, GO:0032760=IEA, GO:0050830=IEA, GO:0042493=IEA, GO:0042534=IEA, GO:0070423=TAS, GO:0046330=IDA, GO:0009620=IEA, GO:0032874=IDA, GO:0042981=IEA, GO:0045408=IEA, GO:0035872=TAS, GO:0042803=IPI, GO:0005737=IDA, GO:0051607=IEA, GO:0045076=IEA, GO:0045087=TAS, GO:0032494=IEA, GO:0032495=IEA, GO:0043123=IEP, GO:0043330=IEA} defense response to Gram-positive bacterium, defense response to virus, innate immune response, nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway, nucleotide-binding oligomerization domain containing signaling pathway, positive regulation of I-kappaB kinase/NF-kappaB cascade, positive regulation of JNK cascade, positive regulation of interleukin-6 production, positive regulation of stress-activated MAPK cascade, positive regulation of tumor necrosis factor production, regulation of apoptotic process, regulation of interleukin-2 biosynthetic process, regulation of interleukin-6 biosynthetic process, regulation of tumor necrosis factor biosynthetic process, response to drug, response to exogenous dsRNA, response to fungus, response to muramyl dipeptide, response to peptidoglycan cytoplasm CARD domain binding, protein homodimerization activity Human CARHSP1 PINC UniProtKB {GO:0035556=PMID:9712905, GO:0043488=GO_REF:0000024, GO:0005737=GO_REF:0000019, GO:0006355=GO_REF:0000002, GO:0019902=PMID:12801884, GO:0000932=GO_REF:0000039, GO:0000177=GO_REF:0000024, GO:0043186=GO_REF:0000024, GO:0003730=PMID:21078874, GO:0003677=GO_REF:0000002, GO:0005829=GO_REF:0000024} Q9Y2V2 Calcium-regulated heat stable protein 1 protein 20030904 {GO:0035556=TAS, GO:0043488=ISS, GO:0005737=IEA, GO:0006355=IEA, GO:0019902=NAS, GO:0000932=IEA, GO:0000177=ISS, GO:0043186=ISS, GO:0003730=IDA, GO:0003677=IEA, GO:0005829=ISS} intracellular signal transduction, regulation of mRNA stability, regulation of transcription, DNA-dependent P granule, cytoplasm, cytoplasmic exosome (RNase complex), cytoplasmic mRNA processing body, cytosol DNA binding, mRNA 3'-UTR binding, phosphatase binding Human CARKD UniProtKB UniProtKB {GO:0005739=GO_REF:0000039, GO:0008150=GO_REF:0000015, GO:0003674=GO_REF:0000015, GO:0005575=GO_REF:0000015, GO:0046496=GO_REF:0000020, GO:0047453=GO_REF:0000003, GO:0005524=GO_REF:0000037} Q8IW45 ATP-dependent (S)-NAD(P)H-hydrate dehydratase protein 20080829 {GO:0005739=IEA, GO:0008150=ND, GO:0003674=ND, GO:0005575=ND, GO:0046496=IEA, GO:0047453=IEA, GO:0005524=IEA} biological_process, nicotinamide nucleotide metabolic process cellular_component, mitochondrion ATP binding, ATP-dependent NAD(P)H-hydrate dehydratase activity, molecular_function Human CARM1 Reactome UniProtKB {GO:0032091=GO_REF:0000019, GO:0008284=GO_REF:0000019, GO:0008013=PMID:16344550, GO:0044212=GO_REF:0000024, GO:0034971=GO_REF:0000024, GO:0008168=GO_REF:0000038, GO:0005634=PMID:15221992, GO:0044281=Reactome:REACT_111217, GO:0051591=GO_REF:0000019, GO:0042803=GO_REF:0000019, GO:0042054=PMID:19405910, GO:0005829=GO_REF:0000024, GO:0005737=PMID:15221992, GO:0030374=GO_REF:0000024, GO:0060350=GO_REF:0000019, GO:0006479=GO_REF:0000002, GO:0070577=GO_REF:0000024, GO:0003420=GO_REF:0000019, GO:0044255=Reactome:REACT_22279, GO:0006355=GO_REF:0000024, GO:0016571=PMID:19405910, GO:0003713=GO_REF:0000024, GO:0016274=GO_REF:0000024, GO:0006351=GO_REF:0000037, GO:0035242=GO_REF:0000024, GO:0019048=GO_REF:0000037, GO:0033146=GO_REF:0000024, GO:0009405=GO_REF:0000002, GO:0045600=GO_REF:0000024, GO:0005654=Reactome:REACT_19175, GO:0035642=GO_REF:0000024, GO:0008276=GO_REF:0000024, GO:0030520=GO_REF:0000019, GO:0034970=PMID:17898714} Q86X55 Histone-arginine methyltransferase CARM1 protein 20130301 {GO:0032091=IEA, GO:0008284=IEA, GO:0008013=TAS, GO:0044212=ISS, GO:0034971=ISS, GO:0008168=IEA, GO:0005634=IDA, GO:0044281=TAS, GO:0051591=IEA, GO:0042803=IEA, GO:0042054=IDA, GO:0005829=ISS, GO:0005737=IDA, GO:0030374=ISS, GO:0060350=IEA, GO:0006479=IEA, GO:0070577=ISS, GO:0003420=IEA, GO:0044255=TAS, GO:0006355=ISS, GO:0016571=IDA, GO:0003713=ISS, GO:0016274=ISS, GO:0006351=IEA, GO:0035242=ISS, GO:0019048=IEA, GO:0033146=ISS, GO:0009405=IEA, GO:0045600=ISS, GO:0005654=TAS, GO:0035642=ISS, GO:0008276=ISS, GO:0030520=IEA, GO:0034970=IMP} cellular lipid metabolic process, endochondral bone morphogenesis, histone H3-R17 methylation, histone H3-R2 methylation, histone methylation, intracellular estrogen receptor signaling pathway, negative regulation of protein binding, pathogenesis, positive regulation of cell proliferation, positive regulation of fat cell differentiation, protein methylation, regulation of growth plate cartilage chondrocyte proliferation, regulation of intracellular estrogen receptor signaling pathway, regulation of transcription, DNA-dependent, response to cAMP, small molecule metabolic process, transcription, DNA-dependent, virus-host interaction cytoplasm, cytosol, nucleoplasm, nucleus beta-catenin binding, histone acetyl-lysine binding, histone methyltransferase activity, histone methyltransferase activity (H3-R17 specific), ligand-dependent nuclear receptor transcription coactivator activity, methyltransferase activity, protein homodimerization activity, protein methyltransferase activity, protein-arginine N-methyltransferase activity, protein-arginine omega-N asymmetric methyltransferase activity, transcription coactivator activity, transcription regulatory region DNA binding Human CARNS1 ENSEMBL UniProtKB {GO:0047730=GO_REF:0000019, GO:0006200=PMID:20097752, GO:0035499=GO_REF:0000019, GO:0005575=GO_REF:0000015, GO:0016887=GO_REF:0000019, GO:0005524=GO_REF:0000002, GO:0046872=GO_REF:0000002} F5H427 Carnosine synthase 1 protein 20130413 {GO:0047730=IEA, GO:0006200=IDA, GO:0035499=IEA, GO:0005575=ND, GO:0016887=IEA, GO:0005524=IEA, GO:0046872=IEA} ATP catabolic process, carnosine biosynthetic process cellular_component ATP binding, ATPase activity, carnosine synthase activity, metal ion binding Human Ensembl:ENSMUSP00000131624 CARS HPA UniProtKB {GO:0005515=PMID:10908348, GO:0006423=PMID:10908348, GO:0010467=Reactome:REACT_71, GO:0005737=GO_REF:0000052, GO:0000049=PMID:7987009, GO:0004817=Reactome:REACT_15527, GO:0005524=PMID:17303165, GO:0042803=PMID:17303165, GO:0046872=GO_REF:0000037, GO:0006418=Reactome:REACT_15482, GO:0005829=Reactome:REACT_15527} P49589 Cysteine--tRNA ligase, cytoplasmic protein 20080205 {GO:0005515=IPI, GO:0006423=IDA, GO:0010467=TAS, GO:0005737=IDA, GO:0000049=NAS, GO:0004817=TAS, GO:0005524=IDA, GO:0042803=IMP, GO:0046872=IEA, GO:0006418=TAS, GO:0005829=TAS} cysteinyl-tRNA aminoacylation, gene expression, tRNA aminoacylation for protein translation cytoplasm, cytosol ATP binding, cysteine-tRNA ligase activity, metal ion binding, protein binding, protein homodimerization activity, tRNA binding Human CARS2 Reactome UniProtKB {GO:0006423=GO_REF:0000033, GO:0010467=Reactome:REACT_71, GO:0004817=GO_REF:0000033, GO:0005759=GO_REF:0000039, GO:0005524=GO_REF:0000037, GO:0046872=GO_REF:0000037, GO:0006418=Reactome:REACT_15482, GO:0005829=GO_REF:0000033} Q9HA77 Probable cysteine--tRNA ligase, mitochondrial protein 20130301 {GO:0006423=IBA, GO:0010467=TAS, GO:0004817=IBA, GO:0005759=IEA, GO:0005524=IEA, GO:0046872=IEA, GO:0006418=TAS, GO:0005829=IBA} cysteinyl-tRNA aminoacylation, gene expression, tRNA aminoacylation for protein translation cytosol, mitochondrial matrix ATP binding, cysteine-tRNA ligase activity, metal ion binding Human CASC1 ENSEMBL UniProtKB {GO:0008017=GO_REF:0000019, GO:0005881=GO_REF:0000019, GO:0048487=GO_REF:0000019} G3V3G6 Cancer susceptibility candidate protein 1 protein 20130413 {GO:0008017=IEA, GO:0005881=IEA, GO:0048487=IEA} cytoplasmic microtubule beta-tubulin binding, microtubule binding Human Ensembl:ENSMUSP00000062279 CASC3 HPA UniProtKB {GO:0005515=PMID:23084401, GO:0006397=GO_REF:0000037, GO:0008380=GO_REF:0000037, GO:0010467=Reactome:REACT_71, GO:0048471=GO_REF:0000039, GO:0008298=GO_REF:0000019, GO:0016070=Reactome:REACT_21257, GO:0016071=Reactome:REACT_20605, GO:0003723=GO_REF:0000037, GO:0005730=GO_REF:0000052, GO:0006950=GO_REF:0000037, GO:0005634=GO_REF:0000052, GO:0006417=GO_REF:0000037, GO:0005829=Reactome:REACT_75910, GO:0042802=PMID:12080473, GO:0008150=GO_REF:0000015, GO:0005737=GO_REF:0000052, GO:0000184=Reactome:REACT_75886, GO:0016607=GO_REF:0000039, GO:0030529=GO_REF:0000019, GO:0051028=GO_REF:0000037, GO:0019899=PMID:21478859, GO:0031625=PMID:21478859, GO:0035145=PMID:16601204} O15234 Protein CASC3 protein 20101115 {GO:0005515=IPI, GO:0006397=IEA, GO:0008380=IEA, GO:0010467=TAS, GO:0048471=IEA, GO:0008298=IEA, GO:0016070=TAS, GO:0016071=TAS, GO:0003723=IEA, GO:0005730=IDA, GO:0006950=IEA, GO:0005634=IDA, GO:0006417=IEA, GO:0005829=TAS, GO:0042802=IDA, GO:0008150=ND, GO:0005737=IDA, GO:0000184=TAS, GO:0016607=IEA, GO:0030529=IEA, GO:0051028=IEA, GO:0019899=IPI, GO:0031625=IPI, GO:0035145=IDA} RNA metabolic process, RNA splicing, biological_process, gene expression, intracellular mRNA localization, mRNA metabolic process, mRNA processing, mRNA transport, nuclear-transcribed mRNA catabolic process, nonsense-mediated decay, regulation of translation, response to stress cytoplasm, cytosol, exon-exon junction complex, nuclear speck, nucleolus, nucleus, perinuclear region of cytoplasm, ribonucleoprotein complex RNA binding, enzyme binding, identical protein binding, protein binding, ubiquitin protein ligase binding Human CASC4 UniProtKB UniProtKB {GO:0016021=GO_REF:0000037} Q6P4E1 Protein CASC4 protein 20130413 {GO:0016021=IEA} integral to membrane Human UniProtKB-KW:KW-0812 CASC5 HPA UniProtKB {GO:0005515=PMID:17981135, GO:0000236=Reactome:REACT_682, GO:0001675=PMID:15579588, GO:0001669=PMID:15579588, GO:0034501=PMID:22331848, GO:0006334=Reactome:REACT_22344, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0005829=Reactome:REACT_150414, GO:0034080=Reactome:REACT_22186, GO:0010923=PMID:19389623, GO:0000087=Reactome:REACT_910, GO:0000777=GO_REF:0000039, GO:0071173=PMID:17981135, GO:0005654=Reactome:REACT_22217, GO:0000278=Reactome:REACT_152, GO:0008608=PMID:17981135, GO:0000090=Reactome:REACT_1275, GO:0051301=GO_REF:0000037} Q8NG31 Protein CASC5 protein 20111111 {GO:0005515=IPI, GO:0000236=TAS, GO:0001675=NAS, GO:0001669=IDA, GO:0034501=IDA, GO:0006334=TAS, GO:0005730=IDA, GO:0005634=IDA, GO:0005829=TAS, GO:0034080=TAS, GO:0010923=IDA, GO:0000087=TAS, GO:0000777=IEA, GO:0071173=IDA, GO:0005654=TAS, GO:0000278=TAS, GO:0008608=IDA, GO:0000090=TAS, GO:0051301=IEA} CENP-A containing nucleosome assembly at centromere, M phase of mitotic cell cycle, acrosome assembly, attachment of spindle microtubules to kinetochore, cell division, mitotic anaphase, mitotic cell cycle, mitotic prometaphase, negative regulation of phosphatase activity, nucleosome assembly, protein localization to kinetochore, spindle assembly checkpoint acrosomal vesicle, condensed chromosome kinetochore, cytosol, nucleolus, nucleoplasm, nucleus protein binding NOT Human CASD1 UniProtKB UniProtKB {GO:0016021=GO_REF:0000037} Q96PB1 CAS1 domain-containing protein 1 protein 20130413 {GO:0016021=IEA} integral to membrane Human UniProtKB-KW:KW-0812 CASK InterPro UniProtKB {GO:0005515=PMID:15694377, GO:0010839=PMID:18664494, GO:0005516=GO_REF:0000037, GO:0060170=GO_REF:0000024, GO:0005886=PMID:9660868, GO:0090288=PMID:18664494, GO:0015629=PMID:9660868, GO:0090280=GO_REF:0000019, GO:0016363=PMID:18664494, GO:0005829=GO_REF:0000019, GO:0016323=GO_REF:0000019, GO:0005737=PMID:18664494, GO:0061045=PMID:18664494, GO:0005911=PMID:18664494, GO:0045944=GO_REF:0000019, GO:0007155=PMID:9660868, GO:0005730=PMID:18664494, GO:0004385=PMID:9660868, GO:0042043=GO_REF:0000019, GO:0005524=GO_REF:0000002, GO:0005604=PMID:18664494, GO:0042734=GO_REF:0000024, GO:0070509=GO_REF:0000019, GO:0004672=GO_REF:0000002, GO:0004674=GO_REF:0000037, GO:0005652=PMID:18664494, GO:0001953=PMID:18664494} Q5JS74 Peripheral plasma membrane protein CASK protein 20130413 {GO:0005515=IPI, GO:0010839=IMP, GO:0005516=IEA, GO:0060170=ISS, GO:0005886=TAS, GO:0090288=IMP, GO:0015629=TAS, GO:0090280=IEA, GO:0016363=IDA, GO:0005829=IEA, GO:0016323=IEA, GO:0005737=IDA, GO:0061045=IMP, GO:0005911=IDA, GO:0045944=IEA, GO:0007155=TAS, GO:0005730=IDA, GO:0004385=TAS, GO:0042043=IEA, GO:0005524=IEA, GO:0005604=IDA, GO:0042734=ISS, GO:0070509=IEA, GO:0004672=IEA, GO:0004674=IEA, GO:0005652=IDA, GO:0001953=IMP} calcium ion import, cell adhesion, negative regulation of cell-matrix adhesion, negative regulation of cellular response to growth factor stimulus, negative regulation of keratinocyte proliferation, negative regulation of wound healing, positive regulation of calcium ion import, positive regulation of transcription from RNA polymerase II promoter actin cytoskeleton, basement membrane, basolateral plasma membrane, cell-cell junction, cilium membrane, cytoplasm, cytosol, nuclear lamina, nuclear matrix, nucleolus, plasma membrane, presynaptic membrane ATP binding, calmodulin binding, guanylate kinase activity, neurexin family protein binding, protein binding, protein kinase activity, protein serine/threonine kinase activity Human InterPro:IPR000719|InterPro:IPR002290 CASKIN1 UniProtKB UniProtKB {GO:0007165=PMID:12040031, GO:0005737=PMID:12040031} Q8WXD9 Caskin-1 protein 20050408 {GO:0007165=ISS, GO:0005737=ISS} signal transduction cytoplasm Human UniProtKB:Q8VHK2 CASKIN2 UniProtKB UniProtKB {GO:0003674=GO_REF:0000015, GO:0008150=GO_REF:0000015, GO:0005737=PMID:12040031} Q8WXE0 Caskin-2 protein 20061026 {GO:0003674=ND, GO:0008150=ND, GO:0005737=ISS} biological_process cytoplasm molecular_function Human CASP1 InterPro UniProtKB {GO:0005515=PMID:18329368, GO:0035872=Reactome:REACT_75913, GO:0005829=Reactome:REACT_75834, GO:0005622=GO_REF:0000002, GO:0050717=GO_REF:0000019, GO:0050718=GO_REF:0000019, GO:0016485=GO_REF:0000019, GO:0006508=PMID:12888622, GO:0033198=GO_REF:0000019, GO:0043123=PMID:12761501, GO:0072559=PMID:15030775, GO:0001666=GO_REF:0000019, GO:0006919=PMID:10799503, GO:0072557=GO_REF:0000024, GO:0071310=PMID:19158679, GO:0072558=PMID:12191486, GO:0006915=PMID:7876192, GO:0005576=GO_REF:0000019, GO:0042981=GO_REF:0000002, GO:0006917=GO_REF:0000019, GO:0008656=PMID:10799503, GO:0004197=Reactome:REACT_23804, GO:0007165=PMID:1373520, GO:0045087=Reactome:REACT_6802, GO:0032611=GO_REF:0000019, GO:0071260=PMID:19593445, GO:0097169=PMID:19158676} Q5FBZ0 Caspase-1 subunit p20 protein 20130413 {GO:0005515=IPI, GO:0035872=TAS, GO:0005829=TAS, GO:0005622=IEA, GO:0050717=IEA, GO:0050718=IEA, GO:0016485=IEA, GO:0006508=IDA, GO:0033198=IEA, GO:0043123=IEP, GO:0072559=IDA, GO:0001666=IEA, GO:0006919=TAS, GO:0072557=ISS, GO:0071310=IDA, GO:0072558=IDA, GO:0006915=TAS, GO:0005576=IEA, GO:0042981=IEA, GO:0006917=IEA, GO:0008656=TAS, GO:0004197=TAS, GO:0007165=TAS, GO:0045087=TAS, GO:0032611=IEA, GO:0071260=IEP, GO:0097169=IDA} activation of cysteine-type endopeptidase activity involved in apoptotic process, apoptotic process, cellular response to mechanical stimulus, cellular response to organic substance, induction of apoptosis, innate immune response, interleukin-1 beta production, nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway, positive regulation of I-kappaB kinase/NF-kappaB cascade, positive regulation of interleukin-1 alpha secretion, positive regulation of interleukin-1 beta secretion, protein processing, proteolysis, regulation of apoptotic process, response to ATP, response to hypoxia, signal transduction AIM2 inflammasome complex, IPAF inflammasome complex, NLRP1 inflammasome complex, NLRP3 inflammasome complex, cytosol, extracellular region, intracellular cysteine-type endopeptidase activator activity involved in apoptotic process, cysteine-type endopeptidase activity, protein binding Human InterPro:IPR001315 CASP10 IntAct UniProtKB {GO:0005515=PMID:21988832, GO:0004197=GO_REF:0000002, GO:0005886=Reactome:REACT_1418, GO:0045087=Reactome:REACT_6802, GO:0006508=GO_REF:0000037, GO:0006915=Reactome:REACT_578, GO:0042981=GO_REF:0000002, GO:0006917=PMID:10412980, GO:0043123=PMID:19641626, GO:0097190=Reactome:REACT_1619, GO:0005829=Reactome:REACT_25167} Q92851 Caspase-10 protein 20130415 {GO:0005515=IPI, GO:0004197=IEA, GO:0005886=TAS, GO:0045087=TAS, GO:0006508=IEA, GO:0006915=TAS, GO:0042981=IEA, GO:0006917=TAS, GO:0043123=RCA, GO:0097190=TAS, GO:0005829=TAS} apoptotic process, apoptotic signaling pathway, induction of apoptosis, innate immune response, positive regulation of I-kappaB kinase/NF-kappaB cascade, proteolysis, regulation of apoptotic process cytosol, plasma membrane cysteine-type endopeptidase activity, protein binding Human UniProtKB:O14730 CASP12 ENSEMBL UniProtKB {GO:0005622=GO_REF:0000002, GO:0004197=GO_REF:0000002, GO:0070059=GO_REF:0000019, GO:0006508=GO_REF:0000002, GO:0006915=GO_REF:0000002, GO:0042981=GO_REF:0000002, GO:0006926=GO_REF:0000019, GO:0030968=GO_REF:0000019} Q6UXS9 Inactive caspase-12 protein 20130413 {GO:0005622=IEA, GO:0004197=IEA, GO:0070059=IEA, GO:0006508=IEA, GO:0006915=IEA, GO:0042981=IEA, GO:0006926=IEA, GO:0030968=IEA} apoptotic process, endoplasmic reticulum unfolded protein response, intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress, proteolysis, regulation of apoptotic process, virus-infected cell apoptotic process intracellular cysteine-type endopeptidase activity Human Ensembl:ENSMUSP00000027009 CASP14 PINC UniProtKB {GO:0004197=GO_REF:0000002, GO:0005737=GO_REF:0000039, GO:0008544=PMID:10203698, GO:0006508=GO_REF:0000037, GO:0006915=GO_REF:0000002, GO:0005634=GO_REF:0000039, GO:0045095=GO_REF:0000019, GO:0030154=GO_REF:0000037} P31944 Caspase-14 protein 20030904 {GO:0004197=IEA, GO:0005737=IEA, GO:0008544=TAS, GO:0006508=IEA, GO:0006915=IEA, GO:0005634=IEA, GO:0045095=IEA, GO:0030154=IEA} apoptotic process, cell differentiation, epidermis development, proteolysis cytoplasm, keratin filament, nucleus cysteine-type endopeptidase activity Human CASP2 BHF-UCL UniProtKB {GO:0005515=PMID:16652156, GO:0048011=Reactome:REACT_13776, GO:0043065=PMID:10980123, GO:0003407=GO_REF:0000019, GO:0019904=PMID:9044836, GO:0007568=GO_REF:0000019, GO:0097194=PMID:18309324, GO:0006915=Reactome:REACT_13526, GO:0001554=GO_REF:0000019, GO:0042981=GO_REF:0000002, GO:0005634=GO_REF:0000019, GO:0006917=GO_REF:0000019, GO:0097190=Reactome:REACT_13720, GO:0005829=Reactome:REACT_13533, GO:0004197=PMID:9044836, GO:0005622=GO_REF:0000002, GO:0005739=GO_REF:0000019, GO:0043525=GO_REF:0000019, GO:0016020=GO_REF:0000019, GO:0016485=PMID:9044836, GO:0007420=GO_REF:0000019, GO:0006508=GO_REF:0000037, GO:0071260=PMID:19593445, GO:0019899=PMID:11076957} P42575 Caspase-2 protein 20090323 {GO:0005515=IPI, GO:0048011=TAS, GO:0043065=IDA, GO:0003407=IEA, GO:0019904=IPI, GO:0007568=IEA, GO:0097194=TAS, GO:0006915=TAS, GO:0001554=IEA, GO:0042981=IEA, GO:0005634=IEA, GO:0006917=IEA, GO:0097190=TAS, GO:0005829=TAS, GO:0004197=IDA, GO:0005622=IEA, GO:0005739=IEA, GO:0043525=IEA, GO:0016020=IEA, GO:0016485=IDA, GO:0007420=IEA, GO:0006508=IEA, GO:0071260=IEP, GO:0019899=ISS} aging, apoptotic process, apoptotic signaling pathway, brain development, cellular response to mechanical stimulus, execution phase of apoptosis, induction of apoptosis, luteolysis, neural retina development, neurotrophin TRK receptor signaling pathway, positive regulation of apoptotic process, positive regulation of neuron apoptotic process, protein processing, proteolysis, regulation of apoptotic process cytosol, intracellular, membrane, mitochondrion, nucleus cysteine-type endopeptidase activity, enzyme binding, protein binding, protein domain specific binding Human UniProtKB:P78560 CASP3 HPA UniProtKB {GO:0005515=PMID:17823127, GO:0008625=GO_REF:0000019, GO:0001782=GO_REF:0000019, GO:0005886=Reactome:REACT_13598, GO:0045736=GO_REF:0000019, GO:0007605=GO_REF:0000019, GO:0046007=GO_REF:0000019, GO:0001836=GO_REF:0000019, GO:0005634=GO_REF:0000052, GO:0051402=GO_REF:0000019, GO:0006921=Reactome:REACT_995, GO:0005829=PMID:17823127, GO:0005739=GO_REF:0000052, GO:0007507=GO_REF:0000019, GO:0005737=GO_REF:0000052, GO:0043525=GO_REF:0000019, GO:0016485=GO_REF:0000019, GO:0006508=PMID:12888622, GO:0043029=GO_REF:0000019, GO:0009411=GO_REF:0000019, GO:0048011=Reactome:REACT_13776, GO:0043066=PMID:9353287, GO:0008635=Reactome:REACT_607, GO:0071310=GO_REF:0000019, GO:0008631=GO_REF:0000019, GO:0005730=GO_REF:0000052, GO:0009611=GO_REF:0000019, GO:0006915=Reactome:REACT_13526, GO:0030889=GO_REF:0000019, GO:0042981=Reactome:REACT_13648, GO:0035329=Reactome:REACT_118607, GO:0006917=GO_REF:0000019, GO:0097190=PMID:10521396, GO:0097193=Reactome:REACT_964, GO:0006974=GO_REF:0000019, GO:0004197=Reactome:REACT_13598, GO:0045165=GO_REF:0000019, GO:0006309=Reactome:REACT_1213, GO:0030216=GO_REF:0000019, GO:0004861=GO_REF:0000019, GO:0030264=PMID:11350920, GO:0034612=PMID:10521396, GO:0005654=Reactome:REACT_13508, GO:0008233=PMID:9353287, GO:0004190=Reactome:REACT_22440} P42574 Caspase-3 protein 20080205 {GO:0005515=IPI, GO:0008625=IEA, GO:0001782=IEA, GO:0005886=TAS, GO:0045736=IEA, GO:0007605=IEA, GO:0046007=IEA, GO:0001836=IEA, GO:0005634=IDA, GO:0051402=IEA, GO:0006921=TAS, GO:0005829=IDA, GO:0005739=IDA, GO:0007507=IEA, GO:0005737=IDA, GO:0043525=IEA, GO:0016485=IEA, GO:0006508=IDA, GO:0043029=IEA, GO:0009411=IEA, GO:0048011=TAS, GO:0043066=IGI, GO:0008635=TAS, GO:0071310=IEA, GO:0008631=IEA, GO:0005730=IDA, GO:0009611=IEA, GO:0006915=TAS, GO:0030889=IEA, GO:0042981=TAS, GO:0035329=TAS, GO:0006917=IEA, GO:0097190=TAS, GO:0097193=TAS, GO:0006974=IEA, GO:0004197=TAS, GO:0045165=IEA, GO:0006309=TAS, GO:0030216=IEA, GO:0004861=IEA, GO:0030264=IMP, GO:0034612=TAS, GO:0005654=TAS, GO:0008233=IDA, GO:0004190=EXP} B cell homeostasis, T cell homeostasis, activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c, apoptotic DNA fragmentation, apoptotic process, apoptotic signaling pathway, cell fate commitment, cellular component disassembly involved in execution phase of apoptosis, cellular response to organic substance, extrinsic apoptotic signaling pathway via death domain receptors, heart development, hippo signaling cascade, induction of apoptosis, intrinsic apoptotic signaling pathway, intrinsic apoptotic signaling pathway in response to oxidative stress, keratinocyte differentiation, negative regulation of B cell proliferation, negative regulation of activated T cell proliferation, negative regulation of apoptotic process, negative regulation of cyclin-dependent protein serine/threonine kinase activity, neuron apoptotic process, neurotrophin TRK receptor signaling pathway, nuclear fragmentation involved in apoptotic nuclear change, positive regulation of neuron apoptotic process, protein processing, proteolysis, regulation of apoptotic process, release of cytochrome c from mitochondria, response to DNA damage stimulus, response to UV, response to tumor necrosis factor, response to wounding, sensory perception of sound cytoplasm, cytosol, mitochondrion, nucleolus, nucleoplasm, nucleus, plasma membrane aspartic-type endopeptidase activity, cyclin-dependent protein serine/threonine kinase inhibitor activity, cysteine-type endopeptidase activity, peptidase activity, protein binding Human CASP4 PINC UniProtKB {GO:0005622=GO_REF:0000002, GO:0004197=GO_REF:0000002, GO:0006508=GO_REF:0000037, GO:0006915=GO_REF:0000037, GO:0042981=GO_REF:0000002, GO:0006917=PMID:7743998} P49662 Caspase-4 protein 20030904 {GO:0005622=IEA, GO:0004197=IEA, GO:0006508=IEA, GO:0006915=IEA, GO:0042981=IEA, GO:0006917=TAS} apoptotic process, induction of apoptosis, proteolysis, regulation of apoptotic process intracellular cysteine-type endopeptidase activity Human CASP5 PINC UniProtKB {GO:0005622=GO_REF:0000002, GO:0004197=GO_REF:0000002, GO:0072558=PMID:12191486, GO:0006508=GO_REF:0000037, GO:0006915=GO_REF:0000037, GO:0042981=GO_REF:0000002, GO:0008234=PMID:7797592, GO:0071260=PMID:19593445} P51878 Caspase-5 protein 20030904 {GO:0005622=IEA, GO:0004197=IEA, GO:0072558=IDA, GO:0006508=IEA, GO:0006915=IEA, GO:0042981=IEA, GO:0008234=TAS, GO:0071260=IEP} apoptotic process, cellular response to mechanical stimulus, proteolysis, regulation of apoptotic process NLRP1 inflammasome complex, intracellular cysteine-type endopeptidase activity, cysteine-type peptidase activity Human CASP6 HPA UniProtKB {GO:0005515=PMID:18408014, GO:0004197=Reactome:REACT_22225, GO:0005737=GO_REF:0000052, GO:0005730=GO_REF:0000052, GO:0006508=PMID:12888622, GO:0006915=Reactome:REACT_578, GO:0005634=GO_REF:0000052, GO:0005654=Reactome:REACT_22225, GO:0008234=PMID:7796396, GO:0006917=PMID:7796396, GO:0006921=Reactome:REACT_995, GO:0005829=Reactome:REACT_13519} P55212 Caspase-6 protein 20120912 {GO:0005515=IPI, GO:0004197=TAS, GO:0005737=IDA, GO:0005730=IDA, GO:0006508=IDA, GO:0006915=TAS, GO:0005634=IDA, GO:0005654=TAS, GO:0008234=TAS, GO:0006917=TAS, GO:0006921=TAS, GO:0005829=TAS} apoptotic process, cellular component disassembly involved in execution phase of apoptosis, induction of apoptosis, proteolysis cytoplasm, cytosol, nucleolus, nucleoplasm, nucleus cysteine-type endopeptidase activity, cysteine-type peptidase activity, protein binding Human CASP7 ENSEMBL UniProtKB {GO:0005515=PMID:11257231, GO:0008635=Reactome:REACT_607, GO:0006915=GO_REF:0000002, GO:0001836=GO_REF:0000019, GO:0006917=GO_REF:0000019, GO:0097193=Reactome:REACT_964, GO:0006921=Reactome:REACT_995, GO:0005829=Reactome:REACT_13428, GO:0007507=GO_REF:0000019, GO:0004197=GO_REF:0000019, GO:0005737=GO_REF:0000002, GO:0043525=GO_REF:0000019, GO:0016485=GO_REF:0000019, GO:0006508=GO_REF:0000002, GO:0005654=Reactome:REACT_13652, GO:0004190=GO_REF:0000019, GO:0008234=PMID:8567622, GO:0009411=GO_REF:0000019} Q5SVL2 Caspase-7 protein 20130413 {GO:0005515=IPI, GO:0008635=TAS, GO:0006915=IEA, GO:0001836=IEA, GO:0006917=IEA, GO:0097193=TAS, GO:0006921=TAS, GO:0005829=TAS, GO:0007507=IEA, GO:0004197=IEA, GO:0005737=IEA, GO:0043525=IEA, GO:0016485=IEA, GO:0006508=IEA, GO:0005654=TAS, GO:0004190=IEA, GO:0008234=TAS, GO:0009411=IEA} activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c, apoptotic process, cellular component disassembly involved in execution phase of apoptosis, heart development, induction of apoptosis, intrinsic apoptotic signaling pathway, positive regulation of neuron apoptotic process, protein processing, proteolysis, release of cytochrome c from mitochondria, response to UV cytoplasm, cytosol, nucleoplasm aspartic-type endopeptidase activity, cysteine-type endopeptidase activity, cysteine-type peptidase activity, protein binding Human Ensembl:ENSMUSP00000026062 CASP8 BHF-UCL UniProtKB {GO:0005515=PMID:22274400, GO:0031265=GO_REF:0000019, GO:0009409=GO_REF:0000019, GO:0031264=PMID:11101870, GO:0097202=PMID:18387192, GO:0042802=PMID:16169070, GO:0007507=GO_REF:0000019, GO:0002756=Reactome:REACT_6809, GO:1900740=Reactome:REACT_701, GO:0051603=PMID:10521396, GO:0032496=GO_REF:0000019, GO:0006508=PMID:12888622, GO:0032025=GO_REF:0000019, GO:0043123=PMID:12761501, GO:0005856=PMID:10891503, GO:0032355=GO_REF:0000019, GO:0046677=GO_REF:0000019, GO:0005164=GO_REF:0000019, GO:0005813=GO_REF:0000052, GO:0030690=GO_REF:0000019, GO:0002224=Reactome:REACT_6966, GO:0001841=GO_REF:0000019, GO:0045087=Reactome:REACT_6802, GO:0045121=GO_REF:0000019, GO:0035666=Reactome:REACT_25281, GO:0008234=PMID:8681376, GO:0043005=GO_REF:0000019, GO:0034142=Reactome:REACT_6894, GO:0045471=GO_REF:0000019, GO:0070423=Reactome:REACT_75776, GO:0005741=Reactome:REACT_13713, GO:0005634=GO_REF:0000052, GO:0051291=GO_REF:0000019, GO:0006921=Reactome:REACT_995, GO:0035872=Reactome:REACT_75913, GO:0005829=Reactome:REACT_150447, GO:0005739=GO_REF:0000052, GO:0005737=GO_REF:0000052, GO:0030225=GO_REF:0000019, GO:0034138=Reactome:REACT_6783, GO:0006919=Reactome:REACT_1503, GO:0005730=GO_REF:0000052, GO:0006915=Reactome:REACT_578, GO:0042981=GO_REF:0000002, GO:0001525=GO_REF:0000019, GO:0097191=PMID:21785459, GO:0097190=PMID:11101870, GO:0044297=GO_REF:0000019, GO:0097193=Reactome:REACT_964, GO:0045862=PMID:18387192, GO:0004197=Reactome:REACT_150381, GO:0019048=GO_REF:0000037, GO:0034612=PMID:10521396, GO:0071260=PMID:19593445} Q14790 Caspase-8 protein 20130219 {GO:0005515=IPI, GO:0031265=IEA, GO:0009409=IEA, GO:0031264=IDA, GO:0097202=IDA, GO:0042802=IPI, GO:0007507=IEA, GO:0002756=TAS, GO:1900740=TAS, GO:0051603=IMP, GO:0032496=IEA, GO:0006508=IDA, GO:0032025=IEA, GO:0043123=IEP, GO:0005856=TAS, GO:0032355=IEA, GO:0046677=IEA, GO:0005164=IEA, GO:0005813=IDA, GO:0030690=IEA, GO:0002224=TAS, GO:0001841=IEA, GO:0045087=TAS, GO:0045121=IEA, GO:0035666=TAS, GO:0008234=TAS, GO:0043005=IEA, GO:0034142=TAS, GO:0045471=IEA, GO:0070423=TAS, GO:0005741=TAS, GO:0005634=IDA, GO:0051291=IEA, GO:0006921=TAS, GO:0035872=TAS, GO:0005829=TAS, GO:0005739=IDA, GO:0005737=IDA, GO:0030225=IEA, GO:0034138=TAS, GO:0006919=TAS, GO:0005730=IDA, GO:0006915=TAS, GO:0042981=IEA, GO:0001525=IEA, GO:0097191=IDA, GO:0097190=IMP, GO:0044297=IEA, GO:0097193=TAS, GO:0045862=IDA, GO:0004197=TAS, GO:0019048=IEA, GO:0034612=IMP, GO:0071260=IEP} MyD88-independent toll-like receptor signaling pathway, TRIF-dependent toll-like receptor signaling pathway, activation of cysteine-type endopeptidase activity, activation of cysteine-type endopeptidase activity involved in apoptotic process, angiogenesis, apoptotic process, apoptotic signaling pathway, cellular component disassembly involved in execution phase of apoptosis, cellular response to mechanical stimulus, extrinsic apoptotic signaling pathway, heart development, innate immune response, intrinsic apoptotic signaling pathway, macrophage differentiation, neural tube formation, nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway, nucleotide-binding oligomerization domain containing signaling pathway, positive regulation of I-kappaB kinase/NF-kappaB cascade, positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway, positive regulation of proteolysis, protein heterooligomerization, proteolysis, proteolysis involved in cellular protein catabolic process, regulation of apoptotic process, response to antibiotic, response to cobalt ion, response to cold, response to estradiol stimulus, response to ethanol, response to lipopolysaccharide, response to tumor necrosis factor, toll-like receptor 3 signaling pathway, toll-like receptor 4 signaling pathway, toll-like receptor signaling pathway, virus-host interaction CD95 death-inducing signaling complex, Noc1p-Noc2p complex, cell body, centrosome, cytoplasm, cytoskeleton, cytosol, death-inducing signaling complex, membrane raft, mitochondrial outer membrane, mitochondrion, neuron projection, nucleolus, nucleus cysteine-type endopeptidase activity, cysteine-type peptidase activity, identical protein binding, protein binding, tumor necrosis factor receptor binding Human CASP8AP2 IntAct UniProtKB {GO:0005515=PMID:21338522, GO:0008625=PMID:17245429, GO:0006355=GO_REF:0000037, GO:0032184=PMID:23086935, GO:0006919=PMID:17245429, GO:0003714=PMID:12477726, GO:0005634=PMID:12477726, GO:0005123=PMID:10235259, GO:0097190=PMID:10235259, GO:0003677=GO_REF:0000002, GO:0008656=GO_REF:0000024, GO:0006351=GO_REF:0000037, GO:0005739=PMID:17245429, GO:0036337=PMID:17245429, GO:0016505=GO_REF:0000024, GO:0007165=PMID:10235259, GO:0007049=GO_REF:0000037, GO:0005737=PMID:17245429, GO:0016605=PMID:17245429, GO:0071260=PMID:19593445} Q9UKL3 CASP8-associated protein 2 protein 20130415 {GO:0005515=IPI, GO:0008625=IMP, GO:0006355=IEA, GO:0032184=IDA, GO:0006919=IMP, GO:0003714=IDA, GO:0005634=IDA, GO:0005123=TAS, GO:0097190=TAS, GO:0003677=IEA, GO:0008656=ISS, GO:0006351=IEA, GO:0005739=IDA, GO:0036337=IMP, GO:0016505=ISS, GO:0007165=TAS, GO:0007049=IEA, GO:0005737=IDA, GO:0016605=IDA, GO:0071260=IEP} Fas signaling pathway, activation of cysteine-type endopeptidase activity involved in apoptotic process, apoptotic signaling pathway, cell cycle, cellular response to mechanical stimulus, extrinsic apoptotic signaling pathway via death domain receptors, regulation of transcription, DNA-dependent, signal transduction, transcription, DNA-dependent PML body, cytoplasm, mitochondrion, nucleus DNA binding, SUMO polymer binding, apoptotic protease activator activity, cysteine-type endopeptidase activator activity involved in apoptotic process, death receptor binding, protein binding, transcription corepressor activity Human UniProtKB:O75925 CASP9 InterPro UniProtKB {GO:0005515=PMID:18022362, GO:0017124=PMID:15657060, GO:2001020=PMID:15657060, GO:0005634=GO_REF:0000019, GO:0005829=GO_REF:0000019, GO:0005622=GO_REF:0000002, GO:0034644=PMID:15657060, GO:0043525=GO_REF:0000019, GO:0043293=PMID:21827945, GO:0007173=Reactome:REACT_9417, GO:0006508=GO_REF:0000002, GO:0009411=GO_REF:0000019, GO:0048011=Reactome:REACT_11061, GO:0008635=Reactome:REACT_607, GO:0019901=PMID:15657060, GO:0008630=PMID:15657060, GO:0006919=GO_REF:0000019, GO:0048015=Reactome:REACT_12464, GO:0006915=GO_REF:0000002, GO:0042981=GO_REF:0000002, GO:0097193=Reactome:REACT_964, GO:0006974=GO_REF:0000019, GO:0004197=GO_REF:0000002, GO:0042770=PMID:15657060, GO:0008543=Reactome:REACT_9470, GO:0045087=Reactome:REACT_6802, GO:0008233=PMID:20663920, GO:0008047=PMID:9390557, GO:0071549=GO_REF:0000019} Q5JRU8 Caspase-9 subunit p35 protein 20130413 {GO:0005515=IPI, GO:0017124=IDA, GO:2001020=IMP, GO:0005634=IEA, GO:0005829=IEA, GO:0005622=IEA, GO:0034644=IDA, GO:0043525=IEA, GO:0043293=IDA, GO:0007173=TAS, GO:0006508=IEA, GO:0009411=IEA, GO:0048011=TAS, GO:0008635=TAS, GO:0019901=IDA, GO:0008630=IMP, GO:0006919=IEA, GO:0048015=TAS, GO:0006915=IEA, GO:0042981=IEA, GO:0097193=TAS, GO:0006974=IEA, GO:0004197=IEA, GO:0042770=IDA, GO:0008543=TAS, GO:0045087=TAS, GO:0008233=IDA, GO:0008047=TAS, GO:0071549=IEA} activation of cysteine-type endopeptidase activity involved in apoptotic process, activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c, apoptotic process, cellular response to UV, cellular response to dexamethasone stimulus, epidermal growth factor receptor signaling pathway, fibroblast growth factor receptor signaling pathway, innate immune response, intrinsic apoptotic signaling pathway, intrinsic apoptotic signaling pathway in response to DNA damage, neurotrophin TRK receptor signaling pathway, phosphatidylinositol-mediated signaling, positive regulation of neuron apoptotic process, proteolysis, regulation of apoptotic process, regulation of response to DNA damage stimulus, response to DNA damage stimulus, response to UV, signal transduction in response to DNA damage apoptosome, cytosol, intracellular, nucleus SH3 domain binding, cysteine-type endopeptidase activity, enzyme activator activity, peptidase activity, protein binding, protein kinase binding Human InterPro:IPR001315 CASQ1 Reactome UniProtKB {GO:0005794=GO_REF:0000019, GO:0010033=GO_REF:0000019, GO:0009408=GO_REF:0000019, GO:0005783=PMID:7945294, GO:0014804=GO_REF:0000019, GO:0005509=GO_REF:0000002, GO:0033017=Reactome:REACT_160216, GO:0030315=GO_REF:0000019, GO:0014894=GO_REF:0000019, GO:0055085=Reactome:REACT_15518, GO:0014809=GO_REF:0000019, GO:0005790=PMID:7945294, GO:0005739=GO_REF:0000019, GO:0034220=Reactome:REACT_25300, GO:0007519=GO_REF:0000019, GO:0005759=PMID:7945294, GO:0007029=GO_REF:0000019, GO:0051282=GO_REF:0000019, GO:0031674=GO_REF:0000019} P31415 Calsequestrin-1 protein 20130301 {GO:0005794=IEA, GO:0010033=IEA, GO:0009408=IEA, GO:0005783=NAS, GO:0014804=IEA, GO:0005509=IEA, GO:0033017=TAS, GO:0030315=IEA, GO:0014894=IEA, GO:0055085=TAS, GO:0014809=IEA, GO:0005790=TAS, GO:0005739=IEA, GO:0034220=TAS, GO:0007519=IEA, GO:0005759=TAS, GO:0007029=IEA, GO:0051282=IEA, GO:0031674=IEA} endoplasmic reticulum organization, ion transmembrane transport, regulation of sequestering of calcium ion, regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion, response to denervation involved in regulation of muscle adaptation, response to heat, response to organic substance, skeletal muscle tissue development, transmembrane transport Golgi apparatus, I band, T-tubule, endoplasmic reticulum, mitochondrial matrix, mitochondrion, sarcoplasmic reticulum membrane, smooth endoplasmic reticulum, terminal cisterna lumen calcium ion binding Human CASQ2 BHF-UCL UniProtKB {GO:0005515=PMID:22123818, GO:0005513=PMID:22123818, GO:0051258=PMID:22123818, GO:0051208=PMID:16601229, GO:0005509=PMID:16601229, GO:0060306=PMID:21063088, GO:0043267=PMID:21063088, GO:0006941=PMID:9795116, GO:0033018=PMID:16908766, GO:0071313=PMID:16908766, GO:0010881=PMID:16601229, GO:0033017=Reactome:REACT_160216, GO:0034704=PMID:19403607, GO:0055085=Reactome:REACT_15518, GO:0005891=GO_REF:0000024, GO:0042803=GO_REF:0000024, GO:0005622=PMID:16908766, GO:0014701=PMID:17569730, GO:0005737=PMID:22123818, GO:0034220=Reactome:REACT_25300, GO:0002027=PMID:16601229, GO:0010880=GO_REF:0000024, GO:0060315=PMID:16601229, GO:0086029=PMID:22198169} O14958 Calsequestrin-2 protein 20130218 {GO:0005515=IPI, GO:0005513=TAS, GO:0051258=IDA, GO:0051208=IDA, GO:0005509=IDA, GO:0060306=ISS, GO:0043267=ISS, GO:0006941=TAS, GO:0033018=IC, GO:0071313=IMP, GO:0010881=IMP, GO:0033017=TAS, GO:0034704=TAS, GO:0055085=TAS, GO:0005891=ISS, GO:0042803=ISS, GO:0005622=IMP, GO:0014701=TAS, GO:0005737=IDA, GO:0034220=TAS, GO:0002027=IMP, GO:0010880=ISS, GO:0060315=IDA, GO:0086029=NAS} Purkinje myocyte to ventricular cardiac muscle cell signaling, cellular response to caffeine, detection of calcium ion, ion transmembrane transport, negative regulation of potassium ion transport, negative regulation of ryanodine-sensitive calcium-release channel activity, protein polymerization, regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion, regulation of heart rate, regulation of membrane repolarization, regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum, sequestering of calcium ion, striated muscle contraction, transmembrane transport calcium channel complex, cytoplasm, intracellular, junctional sarcoplasmic reticulum membrane, sarcoplasmic reticulum lumen, sarcoplasmic reticulum membrane, voltage-gated calcium channel complex calcium ion binding, protein binding, protein homodimerization activity Human CASR IntAct UniProtKB {GO:0005515=PMID:20361938, GO:0005513=PMID:7759551, GO:0008284=GO_REF:0000019, GO:0005886=Reactome:REACT_22436, GO:0007635=PMID:7759551, GO:0004930=GO_REF:0000037, GO:0006874=PMID:7874174, GO:0007254=GO_REF:0000019, GO:0032781=GO_REF:0000019, GO:0009653=PMID:7916660, GO:0010628=GO_REF:0000019, GO:0070509=PMID:20846291, GO:0007186=PMID:7759551, GO:0001503=PMID:7874174, GO:0004435=PMID:7874174, GO:0005887=PMID:7759551, GO:0042311=GO_REF:0000019, GO:0051924=GO_REF:0000019, GO:0006816=GO_REF:0000019, GO:0043679=GO_REF:0000019, GO:0016021=GO_REF:0000038} P41180 Extracellular calcium-sensing receptor protein 20130415 {GO:0005515=IPI, GO:0005513=TAS, GO:0008284=IEA, GO:0005886=TAS, GO:0007635=TAS, GO:0004930=IEA, GO:0006874=TAS, GO:0007254=IEA, GO:0032781=IEA, GO:0009653=TAS, GO:0010628=IEA, GO:0070509=IDA, GO:0007186=TAS, GO:0001503=TAS, GO:0004435=TAS, GO:0005887=TAS, GO:0042311=IEA, GO:0051924=IEA, GO:0006816=IEA, GO:0043679=IEA, GO:0016021=IEA} G-protein coupled receptor signaling pathway, JNK cascade, anatomical structure morphogenesis, calcium ion import, calcium ion transport, cellular calcium ion homeostasis, chemosensory behavior, detection of calcium ion, ossification, positive regulation of ATPase activity, positive regulation of cell proliferation, positive regulation of gene expression, regulation of calcium ion transport, vasodilation axon terminus, integral to membrane, integral to plasma membrane, plasma membrane G-protein coupled receptor activity, phosphatidylinositol phospholipase C activity, protein binding Human UniProtKB:Q15363 CASS4 UniProtKB UniProtKB {GO:0005737=GO_REF:0000037, GO:0016020=GO_REF:0000002, GO:0005856=GO_REF:0000039, GO:0007155=GO_REF:0000037, GO:0005925=GO_REF:0000039, GO:0000155=GO_REF:0000002} Q9NQ75 Cas scaffolding protein family member 4 protein 20130413 {GO:0005737=IEA, GO:0016020=IEA, GO:0005856=IEA, GO:0007155=IEA, GO:0005925=IEA, GO:0000155=IEA} cell adhesion cytoplasm, cytoskeleton, focal adhesion, membrane phosphorelay sensor kinase activity Human UniProtKB-SubCell:SL-0118 CAST GOC UniProtKB {GO:0010951=PMID:7638179, GO:0005515=PMID:17474147, GO:0004869=GO_REF:0000037, GO:0004866=PMID:7638179, GO:0016020=GO_REF:0000019, GO:0010466=GO_REF:0000019} P20810 Calpastatin protein 20130413 {GO:0010951=TAS, GO:0005515=IPI, GO:0004869=IEA, GO:0004866=TAS, GO:0016020=IEA, GO:0010466=IEA} negative regulation of endopeptidase activity, negative regulation of peptidase activity membrane cysteine-type endopeptidase inhibitor activity, endopeptidase inhibitor activity, protein binding Human CASZ1 HPA UniProtKB {GO:0005737=GO_REF:0000052, GO:0006355=GO_REF:0000037, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0008270=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037, GO:0043231=GO_REF:0000052} Q86V15 Zinc finger protein castor homolog 1 protein 20100326 {GO:0005737=IDA, GO:0006355=IEA, GO:0005730=IDA, GO:0005634=IDA, GO:0008270=IEA, GO:0003677=IEA, GO:0006351=IEA, GO:0043231=IDA} regulation of transcription, DNA-dependent, transcription, DNA-dependent cytoplasm, intracellular membrane-bounded organelle, nucleolus, nucleus DNA binding, zinc ion binding Human CAT Reactome UniProtKB {GO:0050661=PMID:10656833, GO:0009650=PMID:17053817, GO:0020027=GO_REF:0000019, GO:0005782=Reactome:REACT_615, GO:0005886=GO_REF:0000019, GO:0004096=Reactome:REACT_615, GO:0005783=GO_REF:0000019, GO:0044281=Reactome:REACT_111217, GO:0042697=GO_REF:0000019, GO:0005764=GO_REF:0000019, GO:0046872=GO_REF:0000037, GO:0042803=PMID:10656833, GO:0005829=GO_REF:0000019, GO:0009060=GO_REF:0000019, GO:0005758=GO_REF:0000019, GO:0006195=Reactome:REACT_2086, GO:0051092=GO_REF:0000019, GO:0051289=PMID:21976670, GO:0051781=GO_REF:0000037, GO:0033197=GO_REF:0000019, GO:0004046=GO_REF:0000019, GO:0042744=PMID:18379038, GO:0005778=GO_REF:0000024, GO:0005777=PMID:18379038, GO:0008203=GO_REF:0000019, GO:0001666=GO_REF:0000019, GO:0043066=PMID:16644728, GO:0005794=GO_REF:0000019, GO:0051262=PMID:11134921, GO:0005102=PMID:21976670, GO:0055086=Reactome:REACT_1698, GO:0014068=GO_REF:0000019, GO:0032088=GO_REF:0000019, GO:0071363=GO_REF:0000019, GO:0006144=Reactome:REACT_522, GO:0055093=GO_REF:0000019, GO:0006641=GO_REF:0000019, GO:0019899=PMID:16781659, GO:0016684=GO_REF:0000024, GO:0000302=PMID:16644728, GO:0020037=PMID:11134921} P04040 Catalase protein 20130213 {GO:0050661=IDA, GO:0009650=IMP, GO:0020027=IEA, GO:0005782=TAS, GO:0005886=IEA, GO:0004096=TAS, GO:0005783=IEA, GO:0044281=TAS, GO:0042697=IEA, GO:0005764=IEA, GO:0046872=IEA, GO:0042803=IDA, GO:0005829=IEA, GO:0009060=IEA, GO:0005758=IEA, GO:0006195=TAS, GO:0051092=IEA, GO:0051289=IDA, GO:0051781=IEA, GO:0033197=IEA, GO:0004046=IEA, GO:0042744=IDA, GO:0005778=ISS, GO:0005777=IDA, GO:0008203=IEA, GO:0001666=IEA, GO:0043066=IMP, GO:0005794=IEA, GO:0051262=IDA, GO:0005102=IPI, GO:0055086=TAS, GO:0014068=IEA, GO:0032088=IEA, GO:0071363=IEA, GO:0006144=TAS, GO:0055093=IEA, GO:0006641=IEA, GO:0019899=IPI, GO:0016684=ISS, GO:0000302=IMP, GO:0020037=IDA} UV protection, aerobic respiration, cellular response to growth factor stimulus, cholesterol metabolic process, hemoglobin metabolic process, hydrogen peroxide catabolic process, menopause, negative regulation of NF-kappaB transcription factor activity, negative regulation of apoptotic process, nucleobase-containing small molecule metabolic process, positive regulation of NF-kappaB transcription factor activity, positive regulation of cell division, positive regulation of phosphatidylinositol 3-kinase cascade, protein homotetramerization, protein tetramerization, purine nucleobase metabolic process, purine nucleotide catabolic process, response to hyperoxia, response to hypoxia, response to reactive oxygen species, response to vitamin E, small molecule metabolic process, triglyceride metabolic process Golgi apparatus, cytosol, endoplasmic reticulum, lysosome, mitochondrial intermembrane space, peroxisomal matrix, peroxisomal membrane, peroxisome, plasma membrane NADP binding, aminoacylase activity, catalase activity, enzyme binding, heme binding, metal ion binding, oxidoreductase activity, acting on peroxide as acceptor, protein homodimerization activity, receptor binding Human CATSPER1 IntAct UniProtKB {GO:0005515=PMID:16740636, GO:0005929=GO_REF:0000037, GO:0005245=GO_REF:0000019, GO:0001539=GO_REF:0000019, GO:0007342=GO_REF:0000019, GO:0036128=GO_REF:0000024, GO:0051924=GO_REF:0000019, GO:0007275=GO_REF:0000037, GO:0030317=GO_REF:0000019, GO:0007283=GO_REF:0000019, GO:0030154=GO_REF:0000037} Q8NEC5 Cation channel sperm-associated protein 1 protein 20130415 {GO:0005515=IPI, GO:0005929=IEA, GO:0005245=IEA, GO:0001539=IEA, GO:0007342=IEA, GO:0036128=ISS, GO:0051924=IEA, GO:0007275=IEA, GO:0030317=IEA, GO:0007283=IEA, GO:0030154=IEA} cell differentiation, ciliary or flagellar motility, fusion of sperm to egg plasma membrane, multicellular organismal development, regulation of calcium ion transport, sperm motility, spermatogenesis CatSper complex, cilium protein binding, voltage-gated calcium channel activity Human UniProtKB:Q9P0X4 CATSPER2 IntAct UniProtKB {GO:0005515=PMID:16740636, GO:0005262=GO_REF:0000037, GO:0005244=GO_REF:0000037, GO:0001539=GO_REF:0000019, GO:0036128=GO_REF:0000024, GO:0007275=GO_REF:0000037, GO:0030317=GO_REF:0000019, GO:0007283=GO_REF:0000037, GO:0030154=GO_REF:0000037, GO:0009566=GO_REF:0000019, GO:0005929=GO_REF:0000037, GO:0016021=GO_REF:0000038, GO:0005216=GO_REF:0000002} Q96P56 Cation channel sperm-associated protein 2 protein 20130415 {GO:0005515=IPI, GO:0005262=IEA, GO:0005244=IEA, GO:0001539=IEA, GO:0036128=ISS, GO:0007275=IEA, GO:0030317=IEA, GO:0007283=IEA, GO:0030154=IEA, GO:0009566=IEA, GO:0005929=IEA, GO:0016021=IEA, GO:0005216=IEA} cell differentiation, ciliary or flagellar motility, fertilization, multicellular organismal development, sperm motility, spermatogenesis CatSper complex, cilium, integral to membrane calcium channel activity, ion channel activity, protein binding, voltage-gated ion channel activity Human UniProtKB:Q9P0X4 CATSPERG UniProtKB UniProtKB {GO:0036128=GO_REF:0000024, GO:0007275=GO_REF:0000037, GO:0007283=GO_REF:0000037, GO:0030154=GO_REF:0000037} Q6ZRH7 Cation channel sperm-associated protein subunit gamma protein 20120329 {GO:0036128=ISS, GO:0007275=IEA, GO:0007283=IEA, GO:0030154=IEA} cell differentiation, multicellular organismal development, spermatogenesis CatSper complex Human UniProtKB:C6KI89 CAV1 BHF-UCL UniProtKB {GO:0005515=PMID:17848177, GO:0043627=PMID:12388746, GO:0019915=GO_REF:0000024, GO:0010524=PMID:19052258, GO:0090263=PMID:16890161, GO:0072584=PMID:19931615, GO:0030879=GO_REF:0000024, GO:0030301=PMID:11294831, GO:0006940=GO_REF:0000024, GO:0050900=Reactome:REACT_12051, GO:2000811=GO_REF:0000019, GO:0052547=GO_REF:0000024, GO:0005113=PMID:11278759, GO:0070836=PMID:12633858, GO:0005622=PMID:15703204, GO:0016050=PMID:12743374, GO:0000165=GO_REF:0000019, GO:0051260=GO_REF:0000024, GO:0031397=GO_REF:0000019, GO:0032507=GO_REF:0000024, GO:0005938=GO_REF:0000019, GO:2000286=PMID:16890161, GO:0005811=Reactome:REACT_12499, GO:0042632=GO_REF:0000024, GO:2001244=PMID:21382479, GO:0000122=GO_REF:0000024, GO:0019217=GO_REF:0000024, GO:0016504=GO_REF:0000024, GO:0043234=GO_REF:0000019, GO:0051592=PMID:19052258, GO:0048554=GO_REF:0000024, GO:0051001=GO_REF:0000019, GO:0007519=GO_REF:0000024, GO:0005887=GO_REF:0000019, GO:0002931=GO_REF:0000019, GO:0032570=PMID:12388746, GO:0006641=GO_REF:0000024, GO:0045121=PMID:17010968, GO:0019899=PMID:20122998, GO:0050998=PMID:12852865, GO:0032091=PMID:16890161, GO:2001238=PMID:21382479, GO:0048471=GO_REF:0000024, GO:0051899=GO_REF:0000024, GO:0005886=PMID:11278759, GO:0005783=PMID:11294831, GO:0050999=Reactome:REACT_12541, GO:0031295=PMID:17287217, GO:0042524=GO_REF:0000019, GO:0044281=Reactome:REACT_111217, GO:0055074=GO_REF:0000024, GO:0044432=PMID:22792322, GO:0000188=GO_REF:0000024, GO:0043409=GO_REF:0000024, GO:0033138=PMID:18081315, GO:0008104=GO_REF:0000024, GO:0001960=GO_REF:0000019, GO:0045907=GO_REF:0000024, GO:0033137=PMID:18081315, GO:0045019=GO_REF:0000024, GO:0033484=GO_REF:0000024, GO:0030857=GO_REF:0000024, GO:0015485=PMID:11294831, GO:0042310=GO_REF:0000019, GO:0046209=Reactome:REACT_12508, GO:0006816=GO_REF:0000024, GO:0002080=GO_REF:0000019, GO:0090090=GO_REF:0000024, GO:0001666=GO_REF:0000024, GO:0051480=PMID:19052258, GO:0060056=GO_REF:0000024, GO:0005102=PMID:16890161, GO:0071455=PMID:21382479, GO:0006874=GO_REF:0000024, GO:0001525=GO_REF:0000019, GO:0097190=PMID:21382479, GO:0046426=GO_REF:0000024, GO:0030666=Reactome:REACT_12634, GO:0032947=PMID:19052258, GO:0030193=PMID:17848177, GO:0007595=GO_REF:0000019, GO:0000139=Reactome:REACT_12637, GO:0007596=Reactome:REACT_604, GO:0001937=GO_REF:0000024, GO:0005198=PMID:11865038, GO:0005901=PMID:18081315, GO:0019048=GO_REF:0000037, GO:0003057=GO_REF:0000019, GO:0001570=GO_REF:0000024, GO:0005768=PMID:20682791} Q03135 Caveolin-1 protein 20080215 {GO:0005515=IPI, GO:0043627=IDA, GO:0019915=ISS, GO:0010524=ISS, GO:0090263=IMP, GO:0072584=IDA, GO:0030879=ISS, GO:0030301=TAS, GO:0006940=ISS, GO:0050900=TAS, GO:2000811=IEA, GO:0052547=ISS, GO:0005113=IPI, GO:0070836=IMP, GO:0005622=IDA, GO:0016050=IDA, GO:0000165=IEA, GO:0051260=ISS, GO:0031397=IEA, GO:0032507=ISS, GO:0005938=IEA, GO:2000286=IMP, GO:0005811=TAS, GO:0042632=ISS, GO:2001244=IMP, GO:0000122=ISS, GO:0019217=ISS, GO:0016504=ISS, GO:0043234=IEA, GO:0051592=ISS, GO:0048554=ISS, GO:0051001=IEA, GO:0007519=ISS, GO:0005887=IEA, GO:0002931=IEA, GO:0032570=IDA, GO:0006641=ISS, GO:0045121=IDA, GO:0019899=IPI, GO:0050998=IPI, GO:0032091=IDA, GO:2001238=IMP, GO:0048471=ISS, GO:0051899=ISS, GO:0005886=IDA, GO:0005783=IDA, GO:0050999=TAS, GO:0031295=IDA, GO:0042524=IEA, GO:0044281=TAS, GO:0055074=ISS, GO:0044432=IDA, GO:0000188=ISS, GO:0043409=ISS, GO:0033138=IDA, GO:0008104=ISS, GO:0001960=IEA, GO:0045907=ISS, GO:0033137=IDA, GO:0045019=ISS, GO:0033484=ISS, GO:0030857=ISS, GO:0015485=TAS, GO:0042310=IEA, GO:0046209=TAS, GO:0006816=ISS, GO:0002080=IEA, GO:0090090=ISS, GO:0001666=ISS, GO:0051480=IDA, GO:0060056=ISS, GO:0005102=IPI, GO:0071455=IMP, GO:0006874=ISS, GO:0001525=IEA, GO:0097190=IMP, GO:0046426=ISS, GO:0030666=TAS, GO:0032947=TAS, GO:0030193=IMP, GO:0007595=IEA, GO:0000139=TAS, GO:0007596=TAS, GO:0001937=ISS, GO:0005198=IDA, GO:0005901=IDA, GO:0019048=IEA, GO:0003057=IEA, GO:0001570=ISS, GO:0005768=IDA} MAPK cascade, T cell costimulation, angiogenesis, apoptotic signaling pathway, blood coagulation, calcium ion homeostasis, calcium ion transport, caveola assembly, caveolin-mediated endocytosis, cellular calcium ion homeostasis, cellular response to hyperoxia, cholesterol homeostasis, cholesterol transport, cytosolic calcium ion homeostasis, inactivation of MAPK activity, lactation, leukocyte migration, lipid storage, maintenance of protein location in cell, mammary gland development, mammary gland involution, membrane depolarization, negative regulation of JAK-STAT cascade, negative regulation of MAPK cascade, negative regulation of anoikis, negative regulation of canonical Wnt receptor signaling pathway, negative regulation of cytokine-mediated signaling pathway, negative regulation of endothelial cell proliferation, negative regulation of epithelial cell differentiation, negative regulation of nitric oxide biosynthetic process, negative regulation of nitric-oxide synthase activity, negative regulation of peptidyl-serine phosphorylation, negative regulation of protein binding, negative regulation of protein ubiquitination, negative regulation of transcription from RNA polymerase II promoter, negative regulation of tyrosine phosphorylation of Stat5 protein, nitric oxide homeostasis, nitric oxide metabolic process, positive regulation of calcium ion transport into cytosol, positive regulation of canonical Wnt receptor signaling pathway, positive regulation of extrinsic apoptotic signaling pathway, positive regulation of intrinsic apoptotic signaling pathway, positive regulation of metalloenzyme activity, positive regulation of peptidyl-serine phosphorylation, positive regulation of vasoconstriction, protein homooligomerization, protein localization, receptor internalization involved in canonical Wnt receptor signaling pathway, regulation of blood coagulation, regulation of fatty acid metabolic process, regulation of nitric-oxide synthase activity, regulation of peptidase activity, regulation of smooth muscle contraction, regulation of the force of heart contraction by chemical signal, response to calcium ion, response to estrogen stimulus, response to hypoxia, response to ischemia, response to progesterone stimulus, skeletal muscle tissue development, small molecule metabolic process, triglyceride metabolic process, vasculogenesis, vasoconstriction, vesicle organization, virus-host interaction Golgi membrane, acrosomal membrane, caveola, cell cortex, endocytic vesicle membrane, endoplasmic reticulum, endoplasmic reticulum part, endosome, integral to plasma membrane, intracellular, lipid particle, membrane raft, perinuclear region of cytoplasm, plasma membrane, protein complex cholesterol binding, enzyme binding, nitric-oxide synthase binding, patched binding, peptidase activator activity, protein binding, protein complex scaffold, receptor binding, structural molecule activity Human CAV2 BHF-UCL UniProtKB {GO:0051219=GO_REF:0000019, GO:0005515=PMID:15703204, GO:0030133=GO_REF:0000054, GO:0048471=PMID:18081315, GO:0005886=PMID:15569306, GO:0007268=GO_REF:0000019, GO:0005634=GO_REF:0000039, GO:0006906=PMID:12743374, GO:0051259=GO_REF:0000019, GO:0042803=PMID:8552590, GO:0070836=PMID:12633858, GO:0005829=GO_REF:0000019, GO:0005622=PMID:15703204, GO:0044432=PMID:22792322, GO:0016050=PMID:12743374, GO:0060161=PMID:15569306, GO:0002080=GO_REF:0000019, GO:0048278=PMID:12743374, GO:0030512=GO_REF:0000019, GO:0019905=GO_REF:0000019, GO:0005811=GO_REF:0000019, GO:0007088=PMID:18081315, GO:0005794=GO_REF:0000024, GO:0009986=GO_REF:0000019, GO:0048741=GO_REF:0000024, GO:0031234=PMID:15569306, GO:0043234=GO_REF:0000019, GO:0001938=GO_REF:0000019, GO:0000139=GO_REF:0000039, GO:0001937=GO_REF:0000024, GO:0005887=PMID:8552590, GO:0005901=PMID:18081315, GO:0045121=PMID:11294831, GO:0007005=GO_REF:0000024, GO:0007029=GO_REF:0000024} P51636 Caveolin-2 protein 20090827 {GO:0051219=IEA, GO:0005515=IPI, GO:0030133=IDA, GO:0048471=IDA, GO:0005886=IDA, GO:0007268=IEA, GO:0005634=IEA, GO:0006906=IDA, GO:0051259=IEA, GO:0042803=IDA, GO:0070836=IMP, GO:0005829=IEA, GO:0005622=IDA, GO:0044432=IDA, GO:0016050=IDA, GO:0060161=IMP, GO:0002080=IEA, GO:0048278=IDA, GO:0030512=IEA, GO:0019905=IEA, GO:0005811=IEA, GO:0007088=IEP, GO:0005794=ISS, GO:0009986=IEA, GO:0048741=ISS, GO:0031234=IDA, GO:0043234=IEA, GO:0001938=IEA, GO:0000139=IEA, GO:0001937=ISS, GO:0005887=IDA, GO:0005901=IDA, GO:0045121=IDA, GO:0007005=ISS, GO:0007029=ISS} caveola assembly, endoplasmic reticulum organization, mitochondrion organization, negative regulation of endothelial cell proliferation, negative regulation of transforming growth factor beta receptor signaling pathway, positive regulation of dopamine receptor signaling pathway, positive regulation of endothelial cell proliferation, protein oligomerization, regulation of mitosis, skeletal muscle fiber development, synaptic transmission, vesicle docking, vesicle fusion, vesicle organization Golgi apparatus, Golgi membrane, acrosomal membrane, caveola, cell surface, cytosol, endoplasmic reticulum part, extrinsic to internal side of plasma membrane, integral to plasma membrane, intracellular, lipid particle, membrane raft, nucleus, perinuclear region of cytoplasm, plasma membrane, protein complex, transport vesicle phosphoprotein binding, protein binding, protein homodimerization activity, syntaxin binding Human CAV3 BHF-UCL UniProtKB {GO:0005515=PMID:10988290, GO:0030018=GO_REF:0000024, GO:0031594=GO_REF:0000024, GO:0008016=GO_REF:0000024, GO:0010831=GO_REF:0000019, GO:0051394=PMID:20472890, GO:0031122=GO_REF:0000019, GO:0060307=PMID:17060380, GO:0032403=PMID:10988290, GO:1900825=PMID:17275750, GO:0030154=GO_REF:0000024, GO:0070836=PMID:18936328, GO:0060373=PMID:17060380, GO:0016010=PMID:10988290, GO:1900744=GO_REF:0000019, GO:0051926=PMID:21084288, GO:0017015=GO_REF:0000019, GO:0071253=PMID:19544087, GO:0051647=GO_REF:0000019, GO:0042632=GO_REF:0000024, GO:0009986=GO_REF:0000019, GO:0060762=GO_REF:0000019, GO:0007520=GO_REF:0000019, GO:0033292=PMID:12847114, GO:0044325=PMID:21084288, GO:0060347=GO_REF:0000019, GO:0045792=PMID:12847114, GO:0007517=PMID:10988290, GO:0061052=GO_REF:0000019, GO:0051001=GO_REF:0000024, GO:0002027=PMID:17060380, GO:0055117=PMID:17275750, GO:0006641=GO_REF:0000024, GO:0016049=GO_REF:0000024, GO:0055013=GO_REF:0000019, GO:0050998=GO_REF:0000019, GO:0008284=GO_REF:0000019, GO:0005886=PMID:20472890, GO:0005783=PMID:22792322, GO:0014819=PMID:17524427, GO:0007204=GO_REF:0000024, GO:0051896=GO_REF:0000019, GO:0010614=PMID:12847114, GO:0038009=PMID:20472890, GO:0043407=PMID:12847114, GO:0042391=PMID:21084288, GO:0001778=GO_REF:0000019, GO:0007015=GO_REF:0000019, GO:0031116=GO_REF:0000024, GO:0090279=PMID:21084288, GO:0043014=GO_REF:0000019, GO:0030315=GO_REF:0000024, GO:0042593=GO_REF:0000024, GO:2000649=PMID:17275750, GO:0008022=PMID:10988290, GO:0031982=GO_REF:0000019, GO:0042383=PMID:17060380, GO:0032947=PMID:17060380, GO:0000139=GO_REF:0000039, GO:0060299=PMID:12847114, GO:0005901=GO_REF:0000039, GO:0090002=GO_REF:0000019, GO:0017080=PMID:17275750} P56539 Caveolin-3 protein 20120801 {GO:0005515=IPI, GO:0030018=ISS, GO:0031594=ISS, GO:0008016=ISS, GO:0010831=IEA, GO:0051394=IMP, GO:0031122=IEA, GO:0060307=IMP, GO:0032403=IDA, GO:1900825=IMP, GO:0030154=ISS, GO:0070836=IDA, GO:0060373=IDA, GO:0016010=IDA, GO:1900744=IEA, GO:0051926=IDA, GO:0017015=IEA, GO:0071253=IDA, GO:0051647=IEA, GO:0042632=ISS, GO:0009986=IEA, GO:0060762=IEA, GO:0007520=IEA, GO:0033292=TAS, GO:0044325=IPI, GO:0060347=IEA, GO:0045792=IMP, GO:0007517=TAS, GO:0061052=IEA, GO:0051001=ISS, GO:0002027=IMP, GO:0055117=IMP, GO:0006641=ISS, GO:0016049=ISS, GO:0055013=IEA, GO:0050998=IEA, GO:0008284=IEA, GO:0005886=IDA, GO:0005783=IDA, GO:0014819=IMP, GO:0007204=ISS, GO:0051896=IEA, GO:0010614=IMP, GO:0038009=IMP, GO:0043407=IMP, GO:0042391=IDA, GO:0001778=IEA, GO:0007015=IEA, GO:0031116=ISS, GO:0090279=IDA, GO:0043014=IEA, GO:0030315=ISS, GO:0042593=ISS, GO:2000649=IDA, GO:0008022=IDA, GO:0031982=IEA, GO:0042383=IDA, GO:0032947=IPI, GO:0000139=IEA, GO:0060299=IMP, GO:0005901=IEA, GO:0090002=IEA, GO:0017080=IMP} T-tubule organization, actin filament organization, cardiac muscle cell development, caveola assembly, cell differentiation, cell growth, cholesterol homeostasis, cytoplasmic microtubule organization, elevation of cytosolic calcium ion concentration, establishment of protein localization to plasma membrane, glucose homeostasis, heart trabecula formation, muscle organ development, myoblast fusion, negative regulation of MAP kinase activity, negative regulation of calcium ion transport, negative regulation of cardiac muscle hypertrophy, negative regulation of cell growth involved in cardiac muscle cell development, negative regulation of cell size, negative regulation of nitric-oxide synthase activity, negative regulation of sarcomere organization, nucleus localization, plasma membrane repair, positive regulation of cell proliferation, positive regulation of microtubule polymerization, positive regulation of myotube differentiation, regulation of branching involved in mammary gland duct morphogenesis, regulation of calcium ion import, regulation of cardiac muscle contraction, regulation of heart contraction, regulation of heart rate, regulation of membrane depolarization involved in regulation of cardiac muscle cell action potential, regulation of membrane potential, regulation of nerve growth factor receptor activity, regulation of p38MAPK cascade, regulation of protein kinase B signaling cascade, regulation of signal transduction by receptor internalization, regulation of skeletal muscle contraction, regulation of sodium ion transmembrane transporter activity, regulation of transforming growth factor beta receptor signaling pathway, regulation of ventricular cardiac muscle cell membrane depolarization, regulation of ventricular cardiac muscle cell membrane repolarization, triglyceride metabolic process Golgi membrane, T-tubule, Z disc, caveola, cell surface, dystrophin-associated glycoprotein complex, endoplasmic reticulum, neuromuscular junction, plasma membrane, sarcolemma, vesicle alpha-tubulin binding, connexin binding, ion channel binding, nitric-oxide synthase binding, protein C-terminus binding, protein binding, protein complex binding, protein complex scaffold, sodium channel regulator activity Human UniProtKB:P51637 CBFA2T2 InterPro UniProtKB {GO:0005515=PMID:19060904, GO:0003700=GO_REF:0000002, GO:0045944=GO_REF:0000019, GO:0003714=PMID:19026687, GO:0010976=PMID:19026687, GO:0030855=GO_REF:0000019, GO:0010977=GO_REF:0000024, GO:0005634=PMID:19026687, GO:0008270=GO_REF:0000002, GO:0045892=GO_REF:0000019} Q5TGE8 Protein CBFA2T2 protein 20130413 {GO:0005515=IPI, GO:0003700=IEA, GO:0045944=IEA, GO:0003714=IDA, GO:0010976=IDA, GO:0030855=IEA, GO:0010977=ISS, GO:0005634=IDA, GO:0008270=IEA, GO:0045892=IEA} epithelial cell differentiation, negative regulation of neuron projection development, negative regulation of transcription, DNA-dependent, positive regulation of neuron projection development, positive regulation of transcription from RNA polymerase II promoter nucleus protein binding, sequence-specific DNA binding transcription factor activity, transcription corepressor activity, zinc ion binding Human InterPro:IPR003894 CBFA2T3 IntAct UniProtKB {GO:0005515=PMID:16966434, GO:0005622=GO_REF:0000019, GO:0003700=GO_REF:0000002, GO:0000139=GO_REF:0000039, GO:0008283=PMID:9447981, GO:0045944=GO_REF:0000019, GO:0003682=GO_REF:0000019, GO:0005730=GO_REF:0000039, GO:0005654=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0030851=PMID:15231665, GO:0006351=GO_REF:0000037} O75081 Protein CBFA2T3 protein 20130415 {GO:0005515=IPI, GO:0005622=IEA, GO:0003700=IEA, GO:0000139=IEA, GO:0008283=TAS, GO:0045944=IEA, GO:0003682=IEA, GO:0005730=IEA, GO:0005654=IEA, GO:0008270=IEA, GO:0030851=IDA, GO:0006351=IEA} cell proliferation, granulocyte differentiation, positive regulation of transcription from RNA polymerase II promoter, transcription, DNA-dependent Golgi membrane, intracellular, nucleolus, nucleoplasm chromatin binding, protein binding, sequence-specific DNA binding transcription factor activity, zinc ion binding Human UniProtKB:Q9Y2D9 CBFB IntAct UniProtKB {GO:0005515=PMID:22190034, GO:0003700=PMID:9751756, GO:0006366=PMID:8351518, GO:0003713=GO_REF:0000002, GO:0005634=GO_REF:0000039, GO:0060216=GO_REF:0000019, GO:0005575=GO_REF:0000015, GO:0003677=GO_REF:0000019, GO:0001649=GO_REF:0000019, GO:0045944=GO_REF:0000019, GO:0030098=GO_REF:0000019, GO:0030099=GO_REF:0000019, GO:0048469=GO_REF:0000019} Q13951 Core-binding factor subunit beta protein 20130415 {GO:0005515=IPI, GO:0003700=TAS, GO:0006366=TAS, GO:0003713=IEA, GO:0005634=IEA, GO:0060216=IEA, GO:0005575=ND, GO:0003677=IEA, GO:0001649=IEA, GO:0045944=IEA, GO:0030098=IEA, GO:0030099=IEA, GO:0048469=IEA} cell maturation, definitive hemopoiesis, lymphocyte differentiation, myeloid cell differentiation, osteoblast differentiation, positive regulation of transcription from RNA polymerase II promoter, transcription from RNA polymerase II promoter cellular_component, nucleus DNA binding, protein binding, sequence-specific DNA binding transcription factor activity, transcription coactivator activity Human UniProtKB:P12504 CBL GOC UniProtKB {GO:0005515=PMID:10068674, GO:0006355=PMID:2030914, GO:0017124=PMID:9447983, GO:0043066=PMID:18070883, GO:0004842=Reactome:REACT_111141, GO:0003700=PMID:2030914, GO:0016567=PMID:15465819, GO:0005886=Reactome:REACT_118834, GO:0005509=GO_REF:0000002, GO:0042059=Reactome:REACT_12484, GO:0014068=PMID:17003487, GO:0005634=GO_REF:0000002, GO:0016600=GO_REF:0000024, GO:0005829=Reactome:REACT_118834, GO:0005737=GO_REF:0000052, GO:0007173=Reactome:REACT_9417, GO:0046875=PMID:18034775, GO:0008543=Reactome:REACT_9470, GO:0048260=PMID:15465819, GO:0001784=GO_REF:0000002, GO:0008270=GO_REF:0000002, GO:0004871=GO_REF:0000002, GO:0007166=PMID:15465819} P22681 E3 ubiquitin-protein ligase CBL protein 20130413 {GO:0005515=IPI, GO:0006355=TAS, GO:0017124=IPI, GO:0043066=IMP, GO:0004842=TAS, GO:0003700=TAS, GO:0016567=TAS, GO:0005886=TAS, GO:0005509=IEA, GO:0042059=TAS, GO:0014068=IMP, GO:0005634=IEA, GO:0016600=ISS, GO:0005829=TAS, GO:0005737=IDA, GO:0007173=TAS, GO:0046875=IPI, GO:0008543=TAS, GO:0048260=TAS, GO:0001784=IEA, GO:0008270=IEA, GO:0004871=IEA, GO:0007166=TAS} cell surface receptor signaling pathway, epidermal growth factor receptor signaling pathway, fibroblast growth factor receptor signaling pathway, negative regulation of apoptotic process, negative regulation of epidermal growth factor receptor signaling pathway, positive regulation of phosphatidylinositol 3-kinase cascade, positive regulation of receptor-mediated endocytosis, protein ubiquitination, regulation of transcription, DNA-dependent cytoplasm, cytosol, flotillin complex, nucleus, plasma membrane SH3 domain binding, calcium ion binding, ephrin receptor binding, phosphotyrosine binding, protein binding, sequence-specific DNA binding transcription factor activity, signal transducer activity, ubiquitin-protein ligase activity, zinc ion binding Human CBLB HPA UniProtKB {GO:0005515=PMID:21706016, GO:0004842=GO_REF:0000002, GO:0045732=GO_REF:0000019, GO:0005886=Reactome:REACT_118834, GO:0023051=GO_REF:0000002, GO:0046642=GO_REF:0000019, GO:0005509=GO_REF:0000002, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0006607=PMID:7784085, GO:0050860=GO_REF:0000019, GO:0005829=Reactome:REACT_118834, GO:0035556=GO_REF:0000019, GO:0007165=PMID:7784085, GO:0006955=GO_REF:0000019, GO:0042110=GO_REF:0000019, GO:0005737=GO_REF:0000052, GO:0002669=GO_REF:0000019, GO:0001784=GO_REF:0000002, GO:0008270=GO_REF:0000002, GO:0004871=GO_REF:0000002, GO:0007166=GO_REF:0000002} Q13191 E3 ubiquitin-protein ligase CBL-B protein 20100326 {GO:0005515=IPI, GO:0004842=IEA, GO:0045732=IEA, GO:0005886=TAS, GO:0023051=IEA, GO:0046642=IEA, GO:0005509=IEA, GO:0005730=IDA, GO:0005634=IDA, GO:0006607=TAS, GO:0050860=IEA, GO:0005829=TAS, GO:0035556=IEA, GO:0007165=TAS, GO:0006955=IEA, GO:0042110=IEA, GO:0005737=IDA, GO:0002669=IEA, GO:0001784=IEA, GO:0008270=IEA, GO:0004871=IEA, GO:0007166=IEA} NLS-bearing substrate import into nucleus, T cell activation, cell surface receptor signaling pathway, immune response, intracellular signal transduction, negative regulation of T cell receptor signaling pathway, negative regulation of alpha-beta T cell proliferation, positive regulation of T cell anergy, positive regulation of protein catabolic process, regulation of signaling, signal transduction cytoplasm, cytosol, nucleolus, nucleus, plasma membrane calcium ion binding, phosphotyrosine binding, protein binding, signal transducer activity, ubiquitin-protein ligase activity, zinc ion binding Human CBLC BHF-UCL UniProtKB {GO:0004842=PMID:14661060, GO:0017124=PMID:10362357, GO:0005154=PMID:10362357, GO:0005509=GO_REF:0000002, GO:0042059=PMID:10362357, GO:0005634=GO_REF:0000039, GO:0042787=PMID:14661060, GO:0043407=PMID:10362357, GO:0007175=PMID:10362357, GO:0008270=GO_REF:0000002, GO:0001784=PMID:14661060, GO:0004871=GO_REF:0000002, GO:0007166=GO_REF:0000002} Q9ULV8 Signal transduction protein CBL-C protein 20090408 {GO:0004842=IDA, GO:0017124=IDA, GO:0005154=IDA, GO:0005509=IEA, GO:0042059=IDA, GO:0005634=IEA, GO:0042787=IDA, GO:0043407=IDA, GO:0007175=IDA, GO:0008270=IEA, GO:0001784=IDA, GO:0004871=IEA, GO:0007166=IEA} cell surface receptor signaling pathway, negative regulation of MAP kinase activity, negative regulation of epidermal growth factor receptor signaling pathway, negative regulation of epidermal growth factor-activated receptor activity, protein ubiquitination involved in ubiquitin-dependent protein catabolic process nucleus SH3 domain binding, calcium ion binding, epidermal growth factor receptor binding, phosphotyrosine binding, signal transducer activity, ubiquitin-protein ligase activity, zinc ion binding Human CBLL1 UniProtKB UniProtKB {GO:0005515=PMID:11836526, GO:0045807=GO_REF:0000024, GO:0016337=PMID:11836526, GO:0007162=GO_REF:0000024, GO:0004842=GO_REF:0000024, GO:0016567=PMID:14996930, GO:0030335=GO_REF:0000024, GO:0000151=PMID:14996930, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002} Q75N03 E3 ubiquitin-protein ligase Hakai protein 20090803 {GO:0005515=IPI, GO:0045807=ISS, GO:0016337=IDA, GO:0007162=ISS, GO:0004842=ISS, GO:0016567=TAS, GO:0030335=ISS, GO:0000151=IC, GO:0008270=IEA, GO:0003676=IEA} cell-cell adhesion, negative regulation of cell adhesion, positive regulation of cell migration, positive regulation of endocytosis, protein ubiquitination ubiquitin ligase complex nucleic acid binding, protein binding, ubiquitin-protein ligase activity, zinc ion binding Human UniProtKB:Q9JIY2 CBLN1 PINC UniProtKB {GO:0051965=GO_REF:0000019, GO:0009306=GO_REF:0000019, GO:0030054=GO_REF:0000037, GO:0005886=GO_REF:0000037, GO:0045211=GO_REF:0000039, GO:0007268=PMID:1704129, GO:0005576=GO_REF:0000039, GO:0042803=GO_REF:0000019, GO:0007399=PMID:1704129} P23435 Cerebellin-1 protein 20030904 {GO:0051965=IEA, GO:0009306=IEA, GO:0030054=IEA, GO:0005886=IEA, GO:0045211=IEA, GO:0007268=TAS, GO:0005576=IEA, GO:0042803=IEA, GO:0007399=TAS} nervous system development, positive regulation of synapse assembly, protein secretion, synaptic transmission cell junction, extracellular region, plasma membrane, postsynaptic membrane protein homodimerization activity Human CBLN2 ENSEMBL UniProtKB {GO:0051965=GO_REF:0000019, GO:0005615=GO_REF:0000019} Q8IUK8 Cerebellin-2 protein 20130413 {GO:0051965=IEA, GO:0005615=IEA} positive regulation of synapse assembly extracellular space Human Ensembl:ENSMUSP00000113695 CBLN3 UniProtKB UniProtKB {GO:0005794=GO_REF:0000039, GO:0030054=GO_REF:0000037, GO:0005783=GO_REF:0000039, GO:0045202=GO_REF:0000039, GO:0005615=GO_REF:0000019} Q6UW01 Cerebellin-3 protein 20130413 {GO:0005794=IEA, GO:0030054=IEA, GO:0005783=IEA, GO:0045202=IEA, GO:0005615=IEA} Golgi apparatus, cell junction, endoplasmic reticulum, extracellular space, synapse Human UniProtKB-SubCell:SL-0258 CBLN4 UniProtKB UniProtKB {GO:0009306=GO_REF:0000019, GO:0030054=GO_REF:0000037, GO:0045202=GO_REF:0000039, GO:0005615=GO_REF:0000019} Q9NTU7 Cerebellin-4 protein 20130413 {GO:0009306=IEA, GO:0030054=IEA, GO:0045202=IEA, GO:0005615=IEA} protein secretion cell junction, extracellular space, synapse Human UniProtKB-SubCell:SL-0258 CBR1 Reactome UniProtKB {GO:0019371=Reactome:REACT_150149, GO:0019369=Reactome:REACT_147851, GO:0047021=GO_REF:0000003, GO:0004090=PMID:18449627, GO:0017144=PMID:18449627, GO:0050221=GO_REF:0000003, GO:0016491=GO_REF:0000002, GO:0044281=Reactome:REACT_111217, GO:0042373=PMID:18449627, GO:0005829=Reactome:REACT_150185, GO:0055114=PMID:19442656} P16152 "Carbonyl reductase ""NADPH"" 1" protein 20130301 {GO:0019371=TAS, GO:0019369=TAS, GO:0047021=IEA, GO:0004090=IDA, GO:0017144=IDA, GO:0050221=IEA, GO:0016491=IEA, GO:0044281=TAS, GO:0042373=IDA, GO:0005829=TAS, GO:0055114=IDA} arachidonic acid metabolic process, cyclooxygenase pathway, drug metabolic process, oxidation-reduction process, small molecule metabolic process, vitamin K metabolic process cytosol 15-hydroxyprostaglandin dehydrogenase (NADP+) activity, carbonyl reductase (NADPH) activity, oxidoreductase activity, prostaglandin-E2 9-reductase activity Human CBR3 HPA UniProtKB {GO:0005737=GO_REF:0000052, GO:0004090=PMID:18493841, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0070402=PMID:18493841, GO:0042376=GO_REF:0000019, GO:0005829=PMID:18493841, GO:0000253=GO_REF:0000019} O75828 "Carbonyl reductase ""NADPH"" 3" protein 20090616 {GO:0005737=IDA, GO:0004090=IDA, GO:0005730=IDA, GO:0005634=IDA, GO:0070402=IDA, GO:0042376=IEA, GO:0005829=IDA, GO:0000253=IEA} phylloquinone catabolic process cytoplasm, cytosol, nucleolus, nucleus 3-keto sterol reductase activity, NADPH binding, carbonyl reductase (NADPH) activity Human CBR4 UniProtKB UniProtKB {GO:0044598=PMID:20837989, GO:0005515=PMID:19571038, GO:0044597=PMID:20837989, GO:0048038=GO_REF:0000024, GO:0051289=PMID:19000905, GO:0005759=GO_REF:0000024, GO:0003955=PMID:20837989, GO:0016491=GO_REF:0000002, GO:0006633=GO_REF:0000041, GO:0070402=GO_REF:0000024, GO:0008753=GO_REF:0000024} Q8N4T8 Carbonyl reductase family member 4 protein 20090828 {GO:0044598=IMP, GO:0005515=IPI, GO:0044597=IMP, GO:0048038=ISS, GO:0051289=IPI, GO:0005759=ISS, GO:0003955=IDA, GO:0016491=IEA, GO:0006633=IEA, GO:0070402=ISS, GO:0008753=ISS} daunorubicin metabolic process, doxorubicin metabolic process, fatty acid biosynthetic process, protein homotetramerization mitochondrial matrix NAD(P)H dehydrogenase (quinone) activity, NADPH binding, NADPH dehydrogenase (quinone) activity, oxidoreductase activity, protein binding, quinone binding Human UniProtKB:Q8N4T8 CBS HPA UniProtKB {GO:0005515=PMID:17087506, GO:0019343=GO_REF:0000002, GO:0070814=GO_REF:0000024, GO:0019346=Reactome:REACT_115589, GO:0006801=GO_REF:0000019, GO:0006535=GO_REF:0000002, GO:0005634=PMID:17087506, GO:0044281=Reactome:REACT_111217, GO:0042803=PMID:11483494, GO:0050667=PMID:20031578, GO:0046872=GO_REF:0000037, GO:0005829=Reactome:REACT_115874, GO:0043231=GO_REF:0000052, GO:0072341=PMID:20031578, GO:0034641=Reactome:REACT_13, GO:0005737=GO_REF:0000002, GO:0050880=GO_REF:0000019, GO:0060351=GO_REF:0000019, GO:0043506=GO_REF:0000019, GO:0004124=GO_REF:0000003, GO:0004122=Reactome:REACT_115874, GO:0031625=PMID:17087506, GO:0043066=GO_REF:0000019, GO:0060135=GO_REF:0000019, GO:0005730=GO_REF:0000052, GO:0021587=GO_REF:0000019, GO:0071456=GO_REF:0000019, GO:0051593=GO_REF:0000019, GO:0001958=GO_REF:0000019, GO:0000096=Reactome:REACT_115639, GO:0043418=PMID:18776696, GO:0001974=GO_REF:0000019, GO:0030170=PMID:7929220, GO:0006563=PMID:19010420, GO:0019899=PMID:17087506, GO:0019448=PMID:15520012, GO:0006565=PMID:18776696, GO:0016740=GO_REF:0000038, GO:0020037=PMID:7929220, GO:0030823=GO_REF:0000019} P35520 Cystathionine beta-synthase protein 20080818 {GO:0005515=IPI, GO:0019343=IEA, GO:0070814=ISS, GO:0019346=TAS, GO:0006801=IEA, GO:0006535=IEA, GO:0005634=IDA, GO:0044281=TAS, GO:0042803=IDA, GO:0050667=IDA, GO:0046872=IEA, GO:0005829=TAS, GO:0043231=IDA, GO:0072341=IDA, GO:0034641=TAS, GO:0005737=IEA, GO:0050880=IEA, GO:0060351=IEA, GO:0043506=IEA, GO:0004124=IEA, GO:0004122=TAS, GO:0031625=IPI, GO:0043066=IEA, GO:0060135=IEA, GO:0005730=IDA, GO:0021587=IEA, GO:0071456=IEA, GO:0051593=IEA, GO:0001958=IEA, GO:0000096=TAS, GO:0043418=IDA, GO:0001974=IEA, GO:0030170=IDA, GO:0006563=IDA, GO:0019899=IPI, GO:0019448=IDA, GO:0006565=IDA, GO:0016740=IEA, GO:0020037=IDA, GO:0030823=IEA} L-cysteine catabolic process, L-serine catabolic process, L-serine metabolic process, blood vessel remodeling, cartilage development involved in endochondral bone morphogenesis, cellular nitrogen compound metabolic process, cellular response to hypoxia, cerebellum morphogenesis, cysteine biosynthetic process from serine, cysteine biosynthetic process via cystathionine, endochondral ossification, homocysteine catabolic process, homocysteine metabolic process, hydrogen sulfide biosynthetic process, maternal process involved in female pregnancy, negative regulation of apoptotic process, regulation of JUN kinase activity, regulation of blood vessel size, regulation of cGMP metabolic process, response to folic acid, small molecule metabolic process, sulfur amino acid metabolic process, superoxide metabolic process, transsulfuration cytoplasm, cytosol, intracellular membrane-bounded organelle, nucleolus, nucleus cystathionine beta-synthase activity, cysteine synthase activity, enzyme binding, heme binding, metal ion binding, modified amino acid binding, protein binding, protein homodimerization activity, pyridoxal phosphate binding, transferase activity, ubiquitin protein ligase binding Human CBWD1 UniProtKB UniProtKB {GO:0005524=GO_REF:0000037} Q9BRT8 COBW domain-containing protein 1 protein 20130413 {GO:0005524=IEA} ATP binding Human UniProtKB-KW:KW-0067 CBWD2 UniProtKB UniProtKB {GO:0005524=GO_REF:0000037} Q8IUF1 COBW domain-containing protein 2 protein 20130413 {GO:0005524=IEA} ATP binding Human UniProtKB-KW:KW-0067 CBWD3 UniProtKB UniProtKB {GO:0005524=GO_REF:0000037} Q5JTY5 COBW domain-containing protein 3 protein 20130413 {GO:0005524=IEA} ATP binding Human UniProtKB-KW:KW-0067 CBWD5 UniProtKB UniProtKB {GO:0005524=GO_REF:0000037} Q5RIA9 COBW domain-containing protein 5 protein 20130413 {GO:0005524=IEA} ATP binding Human UniProtKB-KW:KW-0067 CBWD6 UniProtKB UniProtKB {GO:0005524=GO_REF:0000037} Q4V339 COBW domain-containing protein 6 protein 20130413 {GO:0005524=IEA} ATP binding Human UniProtKB-KW:KW-0067 CBWD7 UniProtKB UniProtKB {GO:0005524=GO_REF:0000037} A6NM15 Putative COBW domain-containing protein 7 protein 20130413 {GO:0005524=IEA} ATP binding Human UniProtKB-KW:KW-0067 CBX1 BHF-UCL UniProtKB {GO:0005515=PMID:9636146, GO:0010369=GO_REF:0000019, GO:0005819=PMID:11101528, GO:0005634=GO_REF:0000038, GO:0042802=GO_REF:0000019, GO:0005720=PMID:9169582, GO:0001939=GO_REF:0000019, GO:0005721=GO_REF:0000019, GO:0003682=PMID:9169582, GO:0005654=PMID:9169582, GO:0001940=GO_REF:0000019, GO:0019899=PMID:19486527, GO:0045892=GO_REF:0000019, GO:0000785=PMID:11101528, GO:0000775=PMID:8287692} P83916 Chromobox protein homolog 1 protein 20081022 {GO:0005515=IPI, GO:0010369=IEA, GO:0005819=IDA, GO:0005634=IEA, GO:0042802=IEA, GO:0005720=TAS, GO:0001939=IEA, GO:0005721=IEA, GO:0003682=TAS, GO:0005654=TAS, GO:0001940=IEA, GO:0019899=IPI, GO:0045892=IEA, GO:0000785=IDA, GO:0000775=IDA} negative regulation of transcription, DNA-dependent centromeric heterochromatin, chromatin, chromocenter, chromosome, centromeric region, female pronucleus, male pronucleus, nuclear heterochromatin, nucleoplasm, nucleus, spindle chromatin binding, enzyme binding, identical protein binding, protein binding Human UniProtKB:P23497-2 CBX2 IntAct UniProtKB {GO:0005515=PMID:19060904, GO:0000792=GO_REF:0000019, GO:0035102=PMID:19636380, GO:0031519=PMID:21282530, GO:0045137=PMID:19361780, GO:0005634=PMID:21282530, GO:0035064=GO_REF:0000019, GO:0000122=PMID:21282530, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037, GO:0030154=GO_REF:0000037, GO:0003682=GO_REF:0000019, GO:0045892=GO_REF:0000029, GO:0016568=GO_REF:0000029} Q14781 Chromobox protein homolog 2 protein 20130415 {GO:0005515=IPI, GO:0000792=IEA, GO:0035102=IDA, GO:0031519=IDA, GO:0045137=IMP, GO:0005634=IDA, GO:0035064=IEA, GO:0000122=IMP, GO:0003677=IEA, GO:0006351=IEA, GO:0030154=IEA, GO:0003682=IEA, GO:0045892=NAS, GO:0016568=NAS} cell differentiation, chromatin modification, development of primary sexual characteristics, negative regulation of transcription from RNA polymerase II promoter, negative regulation of transcription, DNA-dependent, transcription, DNA-dependent PRC1 complex, PcG protein complex, heterochromatin, nucleus DNA binding, chromatin binding, methylated histone residue binding, protein binding Human UniProtKB:Q99750 CBX3 BHF-UCL UniProtKB {GO:0005515=PMID:9636147, GO:0005719=PMID:11124534, GO:0019904=PMID:9636147, GO:0005819=PMID:11101528, GO:0005637=PMID:8663349, GO:0005634=PMID:17540172, GO:0005635=GO_REF:0000024, GO:0006351=GO_REF:0000037, GO:0042802=PMID:21888893, GO:0005720=PMID:11124534, GO:0006338=PMID:8663349, GO:0000779=GO_REF:0000024, GO:0031618=GO_REF:0000024, GO:0019899=PMID:19486527, GO:0045892=PMID:9636147, GO:0000785=PMID:11101528} Q13185 Chromobox protein homolog 3 protein 20081022 {GO:0005515=IPI, GO:0005719=IDA, GO:0019904=IPI, GO:0005819=IDA, GO:0005637=NAS, GO:0005634=IDA, GO:0005635=ISS, GO:0006351=IEA, GO:0042802=IPI, GO:0005720=IDA, GO:0006338=NAS, GO:0000779=ISS, GO:0031618=ISS, GO:0019899=IPI, GO:0045892=IMP, GO:0000785=IDA} chromatin remodeling, negative regulation of transcription, DNA-dependent, transcription, DNA-dependent chromatin, condensed chromosome, centromeric region, nuclear centromeric heterochromatin, nuclear envelope, nuclear euchromatin, nuclear heterochromatin, nuclear inner membrane, nucleus, spindle enzyme binding, identical protein binding, protein binding, protein domain specific binding Human CBX4 HPA UniProtKB {GO:0031519=PMID:21282530, GO:0035102=PMID:19636380, GO:0051219=GO_REF:0000019, GO:0005515=PMID:22078878, GO:0032183=PMID:20176810, GO:0043066=PMID:9315667, GO:0003727=GO_REF:0000019, GO:0005794=GO_REF:0000052, GO:0044212=GO_REF:0000019, GO:0003714=PMID:9315667, GO:0016874=GO_REF:0000037, GO:0016925=GO_REF:0000041, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0000122=PMID:21282530, GO:0035064=GO_REF:0000019, GO:0006351=GO_REF:0000037, GO:0005737=GO_REF:0000052, GO:0016607=GO_REF:0000039, GO:0003682=GO_REF:0000019, GO:0019899=PMID:17087506, GO:0045892=PMID:18567530, GO:0016568=GO_REF:0000037} O00257 E3 SUMO-protein ligase CBX4 protein 20101115 {GO:0031519=IDA, GO:0035102=IDA, GO:0051219=IEA, GO:0005515=IPI, GO:0032183=IDA, GO:0043066=TAS, GO:0003727=IEA, GO:0005794=IDA, GO:0044212=IEA, GO:0003714=TAS, GO:0016874=IEA, GO:0016925=IEA, GO:0005730=IDA, GO:0005634=IDA, GO:0000122=IMP, GO:0035064=IEA, GO:0006351=IEA, GO:0005737=IDA, GO:0016607=IEA, GO:0003682=IEA, GO:0019899=IPI, GO:0045892=IDA, GO:0016568=IEA} chromatin modification, negative regulation of apoptotic process, negative regulation of transcription from RNA polymerase II promoter, negative regulation of transcription, DNA-dependent, protein sumoylation, transcription, DNA-dependent Golgi apparatus, PRC1 complex, PcG protein complex, cytoplasm, nuclear speck, nucleolus, nucleus SUMO binding, chromatin binding, enzyme binding, ligase activity, methylated histone residue binding, phosphoprotein binding, protein binding, single-stranded RNA binding, transcription corepressor activity, transcription regulatory region DNA binding Human CBX5 HPA UniProtKB {GO:0005515=PMID:9636147, GO:0010369=GO_REF:0000019, GO:0042826=GO_REF:0000019, GO:0005730=PMID:9636146, GO:0005634=GO_REF:0000052, GO:0005635=PMID:8663349, GO:0035064=PMID:21029866, GO:0005737=GO_REF:0000052, GO:0005720=PMID:8663349, GO:0035097=GO_REF:0000024, GO:0000118=GO_REF:0000024, GO:0007596=Reactome:REACT_604, GO:0016605=PMID:9636146, GO:0019048=GO_REF:0000037, GO:0003682=GO_REF:0000019, GO:0017053=GO_REF:0000024, GO:0070491=GO_REF:0000024, GO:0000776=GO_REF:0000019, GO:0005654=Reactome:REACT_25059, GO:0031618=PMID:16177824, GO:0019899=PMID:19486527, GO:0030674=GO_REF:0000024, GO:0045892=PMID:9636147} P45973 Chromobox protein homolog 5 protein 20090616 {GO:0005515=IPI, GO:0010369=IEA, GO:0042826=IEA, GO:0005730=IDA, GO:0005634=IDA, GO:0005635=TAS, GO:0035064=IDA, GO:0005737=IDA, GO:0005720=TAS, GO:0035097=ISS, GO:0000118=ISS, GO:0007596=TAS, GO:0016605=IMP, GO:0019048=IEA, GO:0003682=IEA, GO:0017053=ISS, GO:0070491=ISS, GO:0000776=IEA, GO:0005654=TAS, GO:0031618=NAS, GO:0019899=IPI, GO:0030674=ISS, GO:0045892=IMP} blood coagulation, negative regulation of transcription, DNA-dependent, virus-host interaction PML body, chromocenter, cytoplasm, histone deacetylase complex, histone methyltransferase complex, kinetochore, nuclear centromeric heterochromatin, nuclear envelope, nuclear heterochromatin, nucleolus, nucleoplasm, nucleus, transcriptional repressor complex chromatin binding, enzyme binding, histone deacetylase binding, methylated histone residue binding, protein binding, protein binding, bridging, repressing transcription factor binding Human CBX6 IntAct UniProtKB {GO:0005515=PMID:21282530, GO:0031519=PMID:21282530, GO:0000792=GO_REF:0000019, GO:0003727=GO_REF:0000019, GO:0005634=PMID:21282530, GO:0000122=PMID:21282530, GO:0006351=GO_REF:0000037, GO:0016568=GO_REF:0000037} O95503 Chromobox protein homolog 6 protein 20130415 {GO:0005515=IPI, GO:0031519=IDA, GO:0000792=IEA, GO:0003727=IEA, GO:0005634=IDA, GO:0000122=IMP, GO:0006351=IEA, GO:0016568=IEA} chromatin modification, negative regulation of transcription from RNA polymerase II promoter, transcription, DNA-dependent PcG protein complex, heterochromatin, nucleus protein binding, single-stranded RNA binding Human UniProtKB:Q99496 CBX7 IntAct UniProtKB {GO:0031519=PMID:21282530, GO:0035102=GO_REF:0000024, GO:0005515=PMID:21282530, GO:0000792=GO_REF:0000019, GO:0000790=PMID:19636380, GO:0003727=GO_REF:0000019, GO:0005634=PMID:21282530, GO:0000122=PMID:19636380, GO:0035064=GO_REF:0000019, GO:0006351=GO_REF:0000037, GO:0016568=GO_REF:0000037} O95931 Chromobox protein homolog 7 protein 20130415 {GO:0031519=IDA, GO:0035102=ISS, GO:0005515=IPI, GO:0000792=IEA, GO:0000790=IDA, GO:0003727=IEA, GO:0005634=IDA, GO:0000122=IMP, GO:0035064=IEA, GO:0006351=IEA, GO:0016568=IEA} chromatin modification, negative regulation of transcription from RNA polymerase II promoter, transcription, DNA-dependent PRC1 complex, PcG protein complex, heterochromatin, nuclear chromatin, nucleus methylated histone residue binding, protein binding, single-stranded RNA binding Human UniProtKB:Q9BYE7 CBX8 HPA UniProtKB {GO:0000792=GO_REF:0000019, GO:0031519=PMID:21282530, GO:0035102=PMID:19636380, GO:0005515=PMID:22094252, GO:0003727=GO_REF:0000019, GO:0004842=GO_REF:0000019, GO:0000790=PMID:19636380, GO:0016574=GO_REF:0000019, GO:0005730=GO_REF:0000052, GO:0000151=GO_REF:0000019, GO:0005634=GO_REF:0000052, GO:0035064=PMID:21029866, GO:0000122=PMID:19636380, GO:0006351=GO_REF:0000037} Q9HC52 Chromobox protein homolog 8 protein 20101115 {GO:0000792=IEA, GO:0031519=IDA, GO:0035102=IDA, GO:0005515=IPI, GO:0003727=IEA, GO:0004842=IEA, GO:0000790=IDA, GO:0016574=IEA, GO:0005730=IDA, GO:0000151=IEA, GO:0005634=IDA, GO:0035064=IDA, GO:0000122=IMP, GO:0006351=IEA} histone ubiquitination, negative regulation of transcription from RNA polymerase II promoter, transcription, DNA-dependent PRC1 complex, PcG protein complex, heterochromatin, nuclear chromatin, nucleolus, nucleus, ubiquitin ligase complex methylated histone residue binding, protein binding, single-stranded RNA binding, ubiquitin-protein ligase activity NOT Human CBY1 UniProtKB UniProtKB {GO:0005515=PMID:15194699, GO:0005802=PMID:15194699, GO:0005794=GO_REF:0000039, GO:0008013=PMID:12712206, GO:0030178=PMID:12712206, GO:0005634=PMID:12712206, GO:0042802=PMID:15194699, GO:0042384=GO_REF:0000019, GO:0008104=PMID:15194699, GO:0016607=GO_REF:0000039, GO:0045444=GO_REF:0000024, GO:0005932=GO_REF:0000019, GO:0055007=GO_REF:0000024, GO:0090090=GO_REF:0000019, GO:0045892=PMID:12712206} Q9Y3M2 Protein chibby homolog 1 protein 20050322 {GO:0005515=IPI, GO:0005802=IDA, GO:0005794=IEA, GO:0008013=IDA, GO:0030178=IDA, GO:0005634=IDA, GO:0042802=IPI, GO:0042384=IEA, GO:0008104=IMP, GO:0016607=IEA, GO:0045444=ISS, GO:0005932=IEA, GO:0055007=ISS, GO:0090090=IEA, GO:0045892=IDA} cardiac muscle cell differentiation, cilium assembly, fat cell differentiation, negative regulation of Wnt receptor signaling pathway, negative regulation of canonical Wnt receptor signaling pathway, negative regulation of transcription, DNA-dependent, protein localization Golgi apparatus, microtubule basal body, nuclear speck, nucleus, trans-Golgi network beta-catenin binding, identical protein binding, protein binding Human UniProtKB:Q9Y3M2 CC2D1A GOC UniProtKB {GO:0007165=PMID:12761501, GO:0001078=GO_REF:0000019, GO:0005737=GO_REF:0000039, GO:0005815=GO_REF:0000039, GO:0005634=GO_REF:0000039, GO:0004871=PMID:12761501, GO:0043123=PMID:12761501, GO:0000978=GO_REF:0000019} Q6P1N0 Coiled-coil and C2 domain-containing protein 1A protein 20130413 {GO:0007165=IMP, GO:0001078=IEA, GO:0005737=IEA, GO:0005815=IEA, GO:0005634=IEA, GO:0004871=IMP, GO:0043123=IMP, GO:0000978=IEA} positive regulation of I-kappaB kinase/NF-kappaB cascade, signal transduction cytoplasm, microtubule organizing center, nucleus RNA polymerase II core promoter proximal region sequence-specific DNA binding, RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription, signal transducer activity Human CC2D1B UniProtKB UniProtKB {GO:0001078=GO_REF:0000019, GO:0005634=GO_REF:0000039, GO:0000978=GO_REF:0000019} Q5T0F9 Coiled-coil and C2 domain-containing protein 1B protein 20130413 {GO:0001078=IEA, GO:0005634=IEA, GO:0000978=IEA} nucleus RNA polymerase II core promoter proximal region sequence-specific DNA binding, RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription Human UniProtKB-SubCell:SL-0191 CC2D2A UniProtKB UniProtKB {GO:0042384=GO_REF:0000024, GO:0005737=GO_REF:0000039, GO:0035869=GO_REF:0000024, GO:0060271=GO_REF:0000024, GO:0036038=GO_REF:0000024, GO:0005932=GO_REF:0000039, GO:0007224=GO_REF:0000024} Q9P2K1 Coiled-coil and C2 domain-containing protein 2A protein 20120113 {GO:0042384=ISS, GO:0005737=IEA, GO:0035869=ISS, GO:0060271=ISS, GO:0036038=ISS, GO:0005932=IEA, GO:0007224=ISS} cilium assembly, cilium morphogenesis, smoothened signaling pathway TCTN-B9D complex, ciliary transition zone, cytoplasm, microtubule basal body Human UniProtKB:Q8CFW7 CCAR1 IntAct UniProtKB {GO:0005515=PMID:20594350, GO:0008380=Reactome:REACT_1735, GO:0010467=Reactome:REACT_71, GO:0048471=GO_REF:0000039, GO:0007049=GO_REF:0000037, GO:0006355=GO_REF:0000037, GO:0030374=PMID:18722177, GO:0000398=Reactome:REACT_467, GO:0006915=GO_REF:0000037, GO:0005654=Reactome:REACT_1935, GO:0003676=GO_REF:0000002, GO:0006351=GO_REF:0000037} Q8IX12 Cell division cycle and apoptosis regulator protein 1 protein 20130415 {GO:0005515=IPI, GO:0008380=TAS, GO:0010467=TAS, GO:0048471=IEA, GO:0007049=IEA, GO:0006355=IEA, GO:0030374=IGI, GO:0000398=TAS, GO:0006915=IEA, GO:0005654=TAS, GO:0003676=IEA, GO:0006351=IEA} RNA splicing, apoptotic process, cell cycle, gene expression, mRNA splicing, via spliceosome, regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleoplasm, perinuclear region of cytoplasm ligand-dependent nuclear receptor transcription coactivator activity, nucleic acid binding, protein binding Human UniProtKB:Q9GZV5 CCBE1 UniProtKB UniProtKB {GO:0001946=GO_REF:0000024, GO:0005581=GO_REF:0000037, GO:0005509=GO_REF:0000002, GO:0002040=GO_REF:0000024, GO:0048845=GO_REF:0000024} Q6UXH8 Collagen and calcium-binding EGF domain-containing protein 1 protein 20090421 {GO:0001946=ISS, GO:0005581=IEA, GO:0005509=IEA, GO:0002040=ISS, GO:0048845=ISS} lymphangiogenesis, sprouting angiogenesis, venous blood vessel morphogenesis collagen calcium ion binding Human UniProtKB:A8WGB1 CCBL1 HPA UniProtKB {GO:0006559=Reactome:REACT_1786, GO:0006569=Reactome:REACT_916, GO:0070189=PMID:19338303, GO:0009058=GO_REF:0000002, GO:0047312=Reactome:REACT_25224, GO:0008483=PMID:7883047, GO:0005730=GO_REF:0000052, GO:0047804=GO_REF:0000003, GO:0008652=Reactome:REACT_238, GO:0005634=GO_REF:0000052, GO:0044281=Reactome:REACT_111217, GO:0003824=GO_REF:0000002, GO:0016829=GO_REF:0000038, GO:0042803=PMID:15364907, GO:0005829=Reactome:REACT_121130, GO:0034641=Reactome:REACT_13, GO:0097053=GO_REF:0000041, GO:0005737=GO_REF:0000052, GO:0030170=GO_REF:0000002, GO:0006575=PMID:7883047, GO:0047316=GO_REF:0000003, GO:0016212=Reactome:REACT_25349, GO:0036141=Reactome:REACT_121130, GO:0047945=Reactome:REACT_25034} Q5T278 Kynurenine--oxoglutarate transaminase 1 protein 20100326 {GO:0006559=TAS, GO:0006569=TAS, GO:0070189=IDA, GO:0009058=IEA, GO:0047312=EXP, GO:0008483=TAS, GO:0005730=IDA, GO:0047804=IEA, GO:0008652=TAS, GO:0005634=IDA, GO:0044281=TAS, GO:0003824=IEA, GO:0016829=IEA, GO:0042803=IPI, GO:0005829=TAS, GO:0034641=TAS, GO:0097053=IEA, GO:0005737=IDA, GO:0030170=IEA, GO:0006575=TAS, GO:0047316=IEA, GO:0016212=EXP, GO:0036141=TAS, GO:0047945=EXP} L-kynurenine catabolic process, L-phenylalanine catabolic process, biosynthetic process, cellular amino acid biosynthetic process, cellular modified amino acid metabolic process, cellular nitrogen compound metabolic process, kynurenine metabolic process, small molecule metabolic process, tryptophan catabolic process cytoplasm, cytosol, nucleolus, nucleus L-glutamine:pyruvate aminotransferase activity, L-phenylalanine-oxaloacetate transaminase activity, L-phenylalanine:pyruvate aminotransferase activity, catalytic activity, cysteine-S-conjugate beta-lyase activity, glutamine-phenylpyruvate transaminase activity, kynurenine-oxoglutarate transaminase activity, lyase activity, protein homodimerization activity, pyridoxal phosphate binding, transaminase activity Human CCBL2 Reactome UniProtKB {GO:0006520=GO_REF:0000024, GO:0070189=GO_REF:0000024, GO:0006569=Reactome:REACT_916, GO:0009058=GO_REF:0000002, GO:0047804=GO_REF:0000003, GO:0044281=Reactome:REACT_111217, GO:0042803=GO_REF:0000019, GO:0005739=GO_REF:0000019, GO:0034641=Reactome:REACT_13, GO:0030170=GO_REF:0000002, GO:0006103=GO_REF:0000019, GO:0016212=GO_REF:0000024, GO:0047315=GO_REF:0000024} Q6YP21 Kynurenine--oxoglutarate transaminase 3 protein 20130213 {GO:0006520=ISS, GO:0070189=ISS, GO:0006569=TAS, GO:0009058=IEA, GO:0047804=IEA, GO:0044281=TAS, GO:0042803=IEA, GO:0005739=IEA, GO:0034641=TAS, GO:0030170=IEA, GO:0006103=IEA, GO:0016212=ISS, GO:0047315=ISS} 2-oxoglutarate metabolic process, biosynthetic process, cellular amino acid metabolic process, cellular nitrogen compound metabolic process, kynurenine metabolic process, small molecule metabolic process, tryptophan catabolic process mitochondrion cysteine-S-conjugate beta-lyase activity, kynurenine-glyoxylate transaminase activity, kynurenine-oxoglutarate transaminase activity, protein homodimerization activity, pyridoxal phosphate binding Human CCBP2 GOC UniProtKB {GO:0043130=GO_REF:0000002, GO:0070098=PMID:9364936, GO:0005886=Reactome:REACT_21265, GO:0007275=PMID:9364936, GO:0007204=GO_REF:0000002, GO:0019958=GO_REF:0000002, GO:0019957=GO_REF:0000019, GO:0006955=PMID:9364936, GO:0006935=GO_REF:0000002, GO:0007186=PMID:9364936, GO:0016494=GO_REF:0000002, GO:0005887=PMID:9364936, GO:0004950=PMID:9364936, GO:0016493=GO_REF:0000019, GO:0042119=GO_REF:0000002} O00590 Chemokine-binding protein 2 protein 20130413 {GO:0043130=IEA, GO:0070098=TAS, GO:0005886=TAS, GO:0007275=TAS, GO:0007204=IEA, GO:0019958=IEA, GO:0019957=IEA, GO:0006955=TAS, GO:0006935=IEA, GO:0007186=TAS, GO:0016494=IEA, GO:0005887=TAS, GO:0004950=TAS, GO:0016493=IEA, GO:0042119=IEA} G-protein coupled receptor signaling pathway, chemokine-mediated signaling pathway, chemotaxis, elevation of cytosolic calcium ion concentration, immune response, multicellular organismal development, neutrophil activation integral to plasma membrane, plasma membrane C-C chemokine binding, C-C chemokine receptor activity, C-X-C chemokine binding, C-X-C chemokine receptor activity, chemokine receptor activity, ubiquitin binding Human CCDC101 BHF-UCL UniProtKB {GO:0006355=GO_REF:0000037, GO:0071169=PMID:20850016, GO:0043966=PMID:18838386, GO:0005671=PMID:18838386, GO:0035064=PMID:20850016, GO:0006351=GO_REF:0000037, GO:0070461=PMID:18838386} Q96ES7 SAGA-associated factor 29 homolog protein 20101105 {GO:0006355=IEA, GO:0071169=TAS, GO:0043966=IDA, GO:0005671=IDA, GO:0035064=IDA, GO:0006351=IEA, GO:0070461=IDA} establishment of protein localization to chromatin, histone H3 acetylation, regulation of transcription, DNA-dependent, transcription, DNA-dependent Ada2/Gcn5/Ada3 transcription activator complex, SAGA-type complex methylated histone residue binding Human CCDC104 null null {} null null null null {} null null null CCDC106 UniProtKB UniProtKB {GO:0005634=GO_REF:0000039} Q9BWC9 Coiled-coil domain-containing protein 106 protein 20130413 {GO:0005634=IEA} nucleus Human UniProtKB-SubCell:SL-0191 CCDC107 UniProtKB UniProtKB {GO:0016021=GO_REF:0000037} Q8WV48 Coiled-coil domain-containing protein 107 protein 20130413 {GO:0016021=IEA} integral to membrane Human UniProtKB-KW:KW-0812 CCDC109B UniProtKB UniProtKB {GO:0016021=GO_REF:0000037} Q9NWR8 Coiled-coil domain-containing protein 109B protein 20130413 {GO:0016021=IEA} integral to membrane Human UniProtKB-KW:KW-0812 CCDC11 UniProtKB UniProtKB {GO:0003674=GO_REF:0000015, GO:0008150=GO_REF:0000015, GO:0005575=GO_REF:0000015} Q96M91 Coiled-coil domain-containing protein 11 protein 20061026 {GO:0003674=ND, GO:0008150=ND, GO:0005575=ND} biological_process cellular_component molecular_function Human CCDC110 HPA UniProtKB {GO:0005737=GO_REF:0000052, GO:0005794=GO_REF:0000052, GO:0005886=GO_REF:0000052, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0043231=GO_REF:0000052} Q8TBZ0 Coiled-coil domain-containing protein 110 protein 20110516 {GO:0005737=IDA, GO:0005794=IDA, GO:0005886=IDA, GO:0005730=IDA, GO:0005634=IDA, GO:0043231=IDA} Golgi apparatus, cytoplasm, intracellular membrane-bounded organelle, nucleolus, nucleus, plasma membrane Human CCDC112 null null {} null null null null {} null null null CCDC113 HPA UniProtKB {GO:0043234=GO_REF:0000054, GO:0005737=GO_REF:0000052, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052} Q9H0I3 Coiled-coil domain-containing protein 113 protein 20110516 {GO:0043234=IDA, GO:0005737=IDA, GO:0005730=IDA, GO:0005634=IDA} cytoplasm, nucleolus, nucleus, protein complex Human CCDC115 UniProtKB UniProtKB {GO:0005764=GO_REF:0000039, GO:0005768=GO_REF:0000039} Q96NT0 Coiled-coil domain-containing protein 115 protein 20130413 {GO:0005764=IEA, GO:0005768=IEA} endosome, lysosome Human UniProtKB-SubCell:SL-0101 CCDC116 null null {} null null null null {} null null null CCDC117 null null {} null null null null {} null null null CCDC12 null null {} null null null null {} null null null CCDC120 null null {} null null null null {} null null null CCDC124 null null {} null null null null {} null null null CCDC127 null null {} null null null null {} null null null CCDC130 IntAct UniProtKB {GO:0005515=PMID:16189514, GO:0005575=GO_REF:0000015, GO:0009615=PMID:3203696} P13994 Coiled-coil domain-containing protein 130 protein 20130415 {GO:0005515=IPI, GO:0005575=ND, GO:0009615=IEP} response to virus cellular_component protein binding Human UniProtKB:P49910 CCDC132 null null {} null null null null {} null null null CCDC134 UniProtKB UniProtKB {GO:0005576=GO_REF:0000039} Q9H6E4 Coiled-coil domain-containing protein 134 protein 20130413 {GO:0005576=IEA} extracellular region Human UniProtKB-SubCell:SL-0243 CCDC136 ENSEMBL UniProtKB {GO:0005739=GO_REF:0000019, GO:0016021=GO_REF:0000037} Q96JN2 Coiled-coil domain-containing protein 136 protein 20130413 {GO:0005739=IEA, GO:0016021=IEA} integral to membrane, mitochondrion Human Ensembl:ENSMUSP00000093789 CCDC137 null null {} null null null null {} null null null CCDC138 null null {} null null null null {} null null null CCDC14 UniProtKB UniProtKB {GO:0005813=PMID:21399614} Q49A88 Coiled-coil domain-containing protein 14 protein 20110517 {GO:0005813=IDA} centrosome Human CCDC141 IntAct UniProtKB {GO:0005515=PMID:12812986} Q6ZP82 Coiled-coil domain-containing protein 141 protein 20130415 {GO:0005515=IPI} protein binding Human UniProtKB:Q9NRI5 CCDC144A null null {} null null null null {} null null null CCDC144NL null null {} null null null null {} null null null CCDC146 null null {} null null null null {} null null null CCDC147 null null {} null null null null {} null null null CCDC148 null null {} null null null null {} null null null CCDC149 null null {} null null null null {} null null null CCDC15 UniProtKB UniProtKB {GO:0005813=PMID:21399614} Q0P6D6 Coiled-coil domain-containing protein 15 protein 20110517 {GO:0005813=IDA} centrosome Human CCDC155 HPA UniProtKB {GO:0005640=GO_REF:0000039, GO:0000781=GO_REF:0000024, GO:0005794=GO_REF:0000052, GO:0006470=GO_REF:0000002, GO:0005509=GO_REF:0000002, GO:0016021=GO_REF:0000037, GO:0008138=GO_REF:0000002, GO:0043231=GO_REF:0000052} Q8N6L0 Protein KASH5 protein 20100326 {GO:0005640=IEA, GO:0000781=ISS, GO:0005794=IDA, GO:0006470=IEA, GO:0005509=IEA, GO:0016021=IEA, GO:0008138=IEA, GO:0043231=IDA} protein dephosphorylation Golgi apparatus, chromosome, telomeric region, integral to membrane, intracellular membrane-bounded organelle, nuclear outer membrane calcium ion binding, protein tyrosine/serine/threonine phosphatase activity Human CCDC158 null null {} null null null null {} null null null CCDC159 null null {} null null null null {} null null null CCDC167 UniProtKB UniProtKB {GO:0016021=GO_REF:0000037} Q9P0B6 Coiled-coil domain-containing protein 167 protein 20130413 {GO:0016021=IEA} integral to membrane Human UniProtKB-KW:KW-0812 CCDC168 null null {} null null null null {} null null null CCDC17 null null {} null null null null {} null null null CCDC18 null null {} null null null null {} null null null CCDC19 UniProtKB UniProtKB {GO:0005739=GO_REF:0000039, GO:0005634=PMID:10524255} Q9UL16 Coiled-coil domain-containing protein 19, mitochondrial protein 20120803 {GO:0005739=IEA, GO:0005634=NAS} mitochondrion, nucleus Human CCDC22 UniProtKB UniProtKB {GO:0008150=GO_REF:0000015, GO:0003674=GO_REF:0000015, GO:0005575=GO_REF:0000015} O60826 Coiled-coil domain-containing protein 22 protein 20080623 {GO:0008150=ND, GO:0003674=ND, GO:0005575=ND} biological_process cellular_component molecular_function Human CCDC23 MGI UniProtKB {GO:0010596=PMID:20736312, GO:0009306=PMID:20736312, GO:0045177=PMID:20736312, GO:0031397=PMID:20736312} Q8N300 Coiled-coil domain-containing protein 23 protein 20120321 {GO:0010596=IGI, GO:0009306=IDA, GO:0045177=IDA, GO:0031397=IDA} negative regulation of endothelial cell migration, negative regulation of protein ubiquitination, protein secretion apical part of cell Human CCDC24 null null {} null null null null {} null null null CCDC25 null null {} null null null null {} null null null CCDC28A null null {} null null null null {} null null null CCDC28B UniProtKB UniProtKB {GO:0005515=PMID:16327777, GO:0042384=PMID:23015189, GO:0005813=PMID:16327777, GO:0005737=GO_REF:0000037} Q9BUN5 Coiled-coil domain-containing protein 28B protein 20121008 {GO:0005515=IPI, GO:0042384=IMP, GO:0005813=IDA, GO:0005737=IEA} cilium assembly centrosome, cytoplasm protein binding Human CCDC33 IntAct UniProtKB {GO:0005515=PMID:16189514} Q8N5R6 Coiled-coil domain-containing protein 33 protein 20130415 {GO:0005515=IPI} protein binding Human UniProtKB:Q96ED9 CCDC39 BHF-UCL UniProtKB {GO:0001947=PMID:22693285, GO:0060287=PMID:21131972, GO:0060286=PMID:21131972, GO:0035469=PMID:22693285, GO:0071910=PMID:22693285, GO:0030324=PMID:22693285, GO:0060285=PMID:21131972, GO:0070286=PMID:21131972, GO:0035085=PMID:21131974, GO:0005856=GO_REF:0000037, GO:0071907=PMID:22693285} Q9UFE4 Coiled-coil domain-containing protein 39 protein 20130301 {GO:0001947=IMP, GO:0060287=IMP, GO:0060286=IMP, GO:0035469=IMP, GO:0071910=IMP, GO:0030324=IMP, GO:0060285=IMP, GO:0070286=IMP, GO:0035085=IDA, GO:0005856=IEA, GO:0071907=IMP} axonemal dynein complex assembly, ciliary cell motility, determination of digestive tract left/right asymmetry, determination of liver left/right asymmetry, determination of pancreatic left/right asymmetry, epithelial cilium movement involved in determination of left/right asymmetry, flagellar cell motility, heart looping, lung development cilium axoneme, cytoskeleton Human CCDC40 BHF-UCL UniProtKB {GO:0001947=PMID:22693285, GO:0060287=PMID:21131974, GO:0003674=GO_REF:0000015, GO:0060286=GO_REF:0000019, GO:0005929=GO_REF:0000024, GO:0035469=PMID:22693285, GO:0005737=GO_REF:0000024, GO:0071910=PMID:22693285, GO:0030324=PMID:22693285, GO:0060285=GO_REF:0000019, GO:0070286=PMID:21131974, GO:0071907=PMID:22693285} Q4G0X9 Coiled-coil domain-containing protein 40 protein 20120529 {GO:0001947=IMP, GO:0060287=IMP, GO:0003674=ND, GO:0060286=IEA, GO:0005929=ISS, GO:0035469=IMP, GO:0005737=ISS, GO:0071910=IMP, GO:0030324=IMP, GO:0060285=IEA, GO:0070286=IMP, GO:0071907=IMP} axonemal dynein complex assembly, ciliary cell motility, determination of digestive tract left/right asymmetry, determination of liver left/right asymmetry, determination of pancreatic left/right asymmetry, epithelial cilium movement involved in determination of left/right asymmetry, flagellar cell motility, heart looping, lung development cilium, cytoplasm molecular_function Human CCDC41 UniProtKB UniProtKB {GO:0008150=GO_REF:0000015, GO:0003674=GO_REF:0000015, GO:0005575=GO_REF:0000015} Q9Y592 Coiled-coil domain-containing protein 41 protein 20101125 {GO:0008150=ND, GO:0003674=ND, GO:0005575=ND} biological_process cellular_component molecular_function Human CCDC42 null null {} null null null null {} null null null CCDC43 null null {} null null null null {} null null null CCDC47 IntAct UniProtKB {GO:0005515=PMID:21903422, GO:0008150=GO_REF:0000015, GO:0006983=GO_REF:0000019, GO:0005783=GO_REF:0000019, GO:0005509=GO_REF:0000019, GO:0005575=GO_REF:0000015, GO:0009790=GO_REF:0000019, GO:0016021=GO_REF:0000037, GO:0009791=GO_REF:0000019, GO:0055074=GO_REF:0000019} Q96A33 Coiled-coil domain-containing protein 47 protein 20130415 {GO:0005515=IPI, GO:0008150=ND, GO:0006983=IEA, GO:0005783=IEA, GO:0005509=IEA, GO:0005575=ND, GO:0009790=IEA, GO:0016021=IEA, GO:0009791=IEA, GO:0055074=IEA} ER overload response, biological_process, calcium ion homeostasis, embryo development, post-embryonic development cellular_component, endoplasmic reticulum, integral to membrane calcium ion binding, protein binding Human UniProtKB:Q99J34 CCDC50 HPA UniProtKB {GO:0005515=PMID:18029035, GO:0005737=GO_REF:0000052} Q8IVM0 Coiled-coil domain-containing protein 50 protein 20080818 {GO:0005515=IPI, GO:0005737=IDA} cytoplasm protein binding Human CCDC51 HPA UniProtKB {GO:0005739=GO_REF:0000052, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0016021=GO_REF:0000037} Q96ER9 Coiled-coil domain-containing protein 51 protein 20081203 {GO:0005739=IDA, GO:0005730=IDA, GO:0005634=IDA, GO:0016021=IEA} integral to membrane, mitochondrion, nucleolus, nucleus Human CCDC53 IntAct UniProtKB {GO:0005515=PMID:19060904, GO:0008150=GO_REF:0000015, GO:0071203=PMID:19922875} Q9Y3C0 WASH complex subunit CCDC53 protein 20130415 {GO:0005515=IPI, GO:0008150=ND, GO:0071203=IDA} biological_process WASH complex protein binding Human UniProtKB:Q96EZ8 CCDC57 null null {} null null null null {} null null null CCDC58 ENSEMBL UniProtKB {GO:0005739=GO_REF:0000019} Q4VC31 Coiled-coil domain-containing protein 58 protein 20130413 {GO:0005739=IEA} mitochondrion Human Ensembl:ENSMUSP00000125874 CCDC59 IntAct UniProtKB {GO:0005515=PMID:11152647, GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0006351=GO_REF:0000037} Q9P031 Thyroid transcription factor 1-associated protein 26 protein 20130415 {GO:0005515=IPI, GO:0006355=IEA, GO:0005634=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus protein binding Human UniProtKB:P43699 CCDC6 HPA UniProtKB {GO:0008150=GO_REF:0000015, GO:0005737=GO_REF:0000052, GO:0017124=GO_REF:0000037, GO:0005200=PMID:8058316, GO:0005856=GO_REF:0000039} Q16204 Coiled-coil domain-containing protein 6 protein 20110516 {GO:0008150=ND, GO:0005737=IDA, GO:0017124=IEA, GO:0005200=TAS, GO:0005856=IEA} biological_process cytoplasm, cytoskeleton SH3 domain binding, structural constituent of cytoskeleton Human CCDC60 null null {} null null null null {} null null null CCDC64B ENSEMBL UniProtKB {GO:0017137=GO_REF:0000019} A1A5D9 Bicaudal D-related protein 2 protein 20130413 {GO:0017137=IEA} Rab GTPase binding Human Ensembl:ENSMUSP00000053808 CCDC66 null null {} null null null null {} null null null CCDC67 null null {} null null null null {} null null null CCDC68 null null {} null null null null {} null null null CCDC69 null null {} null null null null {} null null null CCDC7 null null {} null null null null {} null null null CCDC71 null null {} null null null null {} null null null CCDC77 UniProtKB UniProtKB {GO:0005813=PMID:21399614} Q9BR77 Coiled-coil domain-containing protein 77 protein 20110517 {GO:0005813=IDA} centrosome Human CCDC78 ENSEMBL UniProtKB {GO:0042383=PMID:22818856, GO:0005737=GO_REF:0000019, GO:0048471=PMID:22818856, GO:0016529=PMID:22818856, GO:0003009=PMID:22818856} I3L158 Coiled-coil domain-containing protein 78 protein 20130413 {GO:0042383=IDA, GO:0005737=IEA, GO:0048471=IDA, GO:0016529=IDA, GO:0003009=IMP} skeletal muscle contraction cytoplasm, perinuclear region of cytoplasm, sarcolemma, sarcoplasmic reticulum Human Ensembl:ENSMUSP00000093155 CCDC8 LIFEdb UniProtKB {GO:0005886=GO_REF:0000054, GO:0010923=PMID:19389623} Q9H0W5 Coiled-coil domain-containing protein 8 protein 20100607 {GO:0005886=IDA, GO:0010923=IDA} negative regulation of phosphatase activity plasma membrane Human CCDC80 ENSEMBL UniProtKB {GO:0030198=GO_REF:0000019, GO:0010811=GO_REF:0000019, GO:0005614=GO_REF:0000019, GO:0001968=GO_REF:0000019, GO:0008201=GO_REF:0000019, GO:0005604=GO_REF:0000019} Q76M96 Coiled-coil domain-containing protein 80 protein 20130413 {GO:0030198=IEA, GO:0010811=IEA, GO:0005614=IEA, GO:0001968=IEA, GO:0008201=IEA, GO:0005604=IEA} extracellular matrix organization, positive regulation of cell-substrate adhesion basement membrane, interstitial matrix fibronectin binding, heparin binding Human Ensembl:ENSMUSP00000097097 CCDC82 null null {} null null null null {} null null null CCDC85A null null {} null null null null {} null null null CCDC85B IntAct UniProtKB {GO:0005515=PMID:16189514, GO:0030308=PMID:17873903, GO:0005813=PMID:17014843, GO:0005737=GO_REF:0000037, GO:0045599=GO_REF:0000024, GO:0005634=PMID:17873903, GO:0045892=PMID:17014843, GO:0030154=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q15834 Coiled-coil domain-containing protein 85B protein 20130415 {GO:0005515=IPI, GO:0030308=IDA, GO:0005813=IDA, GO:0005737=IEA, GO:0045599=ISS, GO:0005634=IDA, GO:0045892=IDA, GO:0030154=IEA, GO:0006351=IEA} cell differentiation, negative regulation of cell growth, negative regulation of fat cell differentiation, negative regulation of transcription, DNA-dependent, transcription, DNA-dependent centrosome, cytoplasm, nucleus protein binding Human UniProtKB:Q9UFG5 CCDC85C ENSEMBL UniProtKB {GO:0043296=GO_REF:0000019, GO:0021987=GO_REF:0000019, GO:0005923=GO_REF:0000039} G3V5D5 Coiled-coil domain-containing protein 85C protein 20130413 {GO:0043296=IEA, GO:0021987=IEA, GO:0005923=IEA} cerebral cortex development apical junction complex, tight junction Human Ensembl:ENSMUSP00000125757 CCDC86 HPA UniProtKB {GO:0019048=GO_REF:0000037, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052} Q9H6F5 Coiled-coil domain-containing protein 86 protein 20111111 {GO:0019048=IEA, GO:0005730=IDA, GO:0005634=IDA} virus-host interaction nucleolus, nucleus Human CCDC87 InterPro UniProtKB {GO:0008017=GO_REF:0000002, GO:0000910=GO_REF:0000002, GO:0000226=GO_REF:0000002} Q9NVE4 Coiled-coil domain-containing protein 87 protein 20130413 {GO:0008017=IEA, GO:0000910=IEA, GO:0000226=IEA} cytokinesis, microtubule cytoskeleton organization microtubule binding Human InterPro:IPR007145 CCDC88A UniProtKB UniProtKB {GO:0008017=GO_REF:0000024, GO:0005886=PMID:15882442, GO:0005783=PMID:15882442, GO:0030032=PMID:16139227, GO:0042803=PMID:16139227, GO:0005829=PMID:15749703, GO:0005737=GO_REF:0000002, GO:0042127=GO_REF:0000024, GO:0032956=PMID:16139227, GO:0032148=GO_REF:0000024, GO:0006275=GO_REF:0000024, GO:0031929=GO_REF:0000024, GO:0005794=PMID:15882442, GO:0000226=GO_REF:0000002, GO:0003779=PMID:16139227, GO:0031410=PMID:15882442, GO:0043422=PMID:16139227, GO:0030027=PMID:16139227, GO:0006260=GO_REF:0000037, GO:0016020=PMID:15749703, GO:0016477=PMID:16139227, GO:0010975=GO_REF:0000024, GO:0016023=GO_REF:0000039, GO:0001932=GO_REF:0000024, GO:0035091=PMID:16139227, GO:0016044=PMID:15882442} Q3V6T2 Girdin protein 20100304 {GO:0008017=ISS, GO:0005886=IDA, GO:0005783=IDA, GO:0030032=IMP, GO:0042803=IPI, GO:0005829=IDA, GO:0005737=IEA, GO:0042127=ISS, GO:0032956=IMP, GO:0032148=ISS, GO:0006275=ISS, GO:0031929=ISS, GO:0005794=IDA, GO:0000226=IEA, GO:0003779=IDA, GO:0031410=IDA, GO:0043422=IPI, GO:0030027=IDA, GO:0006260=IEA, GO:0016020=IDA, GO:0016477=IMP, GO:0010975=ISS, GO:0016023=IEA, GO:0001932=ISS, GO:0035091=IDA, GO:0016044=IDA} DNA replication, TOR signaling cascade, activation of protein kinase B activity, cell migration, cellular membrane organization, lamellipodium assembly, microtubule cytoskeleton organization, regulation of DNA replication, regulation of actin cytoskeleton organization, regulation of cell proliferation, regulation of neuron projection development, regulation of protein phosphorylation Golgi apparatus, cytoplasm, cytoplasmic membrane-bounded vesicle, cytoplasmic vesicle, cytosol, endoplasmic reticulum, lamellipodium, membrane, plasma membrane actin binding, microtubule binding, phosphatidylinositol binding, protein homodimerization activity, protein kinase B binding Human UniProtKB:Q5SNZ0 CCDC88B InterPro UniProtKB {GO:0008017=GO_REF:0000002, GO:0005737=GO_REF:0000002, GO:0000226=GO_REF:0000002} A6NC98 Coiled-coil domain-containing protein 88B protein 20130413 {GO:0008017=IEA, GO:0005737=IEA, GO:0000226=IEA} microtubule cytoskeleton organization cytoplasm microtubule binding Human InterPro:IPR008636 CCDC88C UniProtKB UniProtKB {GO:0031648=PMID:14750955, GO:0008017=GO_REF:0000002, GO:0005737=GO_REF:0000002, GO:0000226=GO_REF:0000002, GO:0051260=PMID:14750955, GO:0001932=PMID:14750955, GO:0043621=PMID:14750955, GO:0030165=PMID:14750955, GO:0016055=GO_REF:0000037} Q9P219 Protein Daple protein 20070418 {GO:0031648=ISS, GO:0008017=IEA, GO:0005737=IEA, GO:0000226=IEA, GO:0051260=ISS, GO:0001932=ISS, GO:0043621=ISS, GO:0030165=ISS, GO:0016055=IEA} Wnt receptor signaling pathway, microtubule cytoskeleton organization, protein destabilization, protein homooligomerization, regulation of protein phosphorylation cytoplasm PDZ domain binding, microtubule binding, protein self-association Human UniProtKB:Q6VGS5 CCDC89 UniProtKB UniProtKB {GO:0005737=GO_REF:0000039, GO:0005634=GO_REF:0000039} Q8N998 Coiled-coil domain-containing protein 89 protein 20130413 {GO:0005737=IEA, GO:0005634=IEA} cytoplasm, nucleus Human UniProtKB-SubCell:SL-0086 CCDC9 null null {} null null null null {} null null null CCDC90B HPA UniProtKB {GO:0005739=GO_REF:0000052, GO:0016021=GO_REF:0000037} Q9GZT6 Coiled-coil domain-containing protein 90B, mitochondrial protein 20081203 {GO:0005739=IDA, GO:0016021=IEA} integral to membrane, mitochondrion Human CCDC91 HPA UniProtKB {GO:0005794=GO_REF:0000052, GO:0016020=GO_REF:0000039, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0015031=GO_REF:0000037, GO:0042802=GO_REF:0000019} Q7Z6B0 Coiled-coil domain-containing protein 91 protein 20110516 {GO:0005794=IDA, GO:0016020=IEA, GO:0005730=IDA, GO:0005634=IDA, GO:0015031=IEA, GO:0042802=IEA} protein transport Golgi apparatus, membrane, nucleolus, nucleus identical protein binding Human CCDC92 UniProtKB UniProtKB {GO:0005515=PMID:22863007, GO:0005814=PMID:22863007} Q53HC0 Coiled-coil domain-containing protein 92 protein 20120816 {GO:0005515=IPI, GO:0005814=IDA} centriole protein binding Human CCDC93 null null {} null null null null {} null null null CCDC94 null null {} null null null null {} null null null CCDC97 null null {} null null null null {} null null null CCHCR1 HPA UniProtKB {GO:0005737=GO_REF:0000039, GO:0006611=GO_REF:0000019, GO:0007275=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0030154=GO_REF:0000037, GO:0043231=GO_REF:0000052} Q8TD31 Coiled-coil alpha-helical rod protein 1 protein 20120912 {GO:0005737=IEA, GO:0006611=IEA, GO:0007275=IEA, GO:0005634=IEA, GO:0030154=IEA, GO:0043231=IDA} cell differentiation, multicellular organismal development, protein export from nucleus cytoplasm, intracellular membrane-bounded organelle, nucleus Human CCIN UniProtKB UniProtKB {GO:0033150=GO_REF:0000039, GO:0005200=GO_REF:0000029, GO:0007275=GO_REF:0000037, GO:0007283=GO_REF:0000029, GO:0005856=GO_REF:0000029, GO:0030154=GO_REF:0000037} Q13939 Calicin protein 20021104 {GO:0033150=IEA, GO:0005200=NAS, GO:0007275=IEA, GO:0007283=NAS, GO:0005856=NAS, GO:0030154=IEA} cell differentiation, multicellular organismal development, spermatogenesis cytoskeletal calyx, cytoskeleton structural constituent of cytoskeleton Human CCK Reactome UniProtKB {GO:0030424=PMID:15152034, GO:0008284=GO_REF:0000019, GO:0032099=GO_REF:0000019, GO:0050731=GO_REF:0000019, GO:0001836=GO_REF:0000019, GO:0007409=PMID:15152034, GO:0005615=GO_REF:0000019, GO:0030425=GO_REF:0000019, GO:0007205=GO_REF:0000019, GO:0043194=GO_REF:0000019, GO:0051901=GO_REF:0000019, GO:0043195=GO_REF:0000019, GO:0043203=GO_REF:0000019, GO:0043204=GO_REF:0000019, GO:0001662=GO_REF:0000019, GO:0032461=GO_REF:0000019, GO:0005184=PMID:15374756, GO:0043065=GO_REF:0000019, GO:0006919=GO_REF:0000019, GO:0005576=Reactome:REACT_22436, GO:0007165=PMID:10320330, GO:0005179=PMID:10320330, GO:0042755=PMID:15374756, GO:0001764=PMID:15152034, GO:0051930=GO_REF:0000019} P06307 Cholecystokinin protein 20081212 {GO:0030424=ISS, GO:0008284=IEA, GO:0032099=IEA, GO:0050731=IEA, GO:0001836=IEA, GO:0007409=ISS, GO:0005615=IEA, GO:0030425=IEA, GO:0007205=IEA, GO:0043194=IEA, GO:0051901=IEA, GO:0043195=IEA, GO:0043203=IEA, GO:0043204=IEA, GO:0001662=IEA, GO:0032461=IEA, GO:0005184=ISS, GO:0043065=IEA, GO:0006919=IEA, GO:0005576=TAS, GO:0007165=TAS, GO:0005179=TAS, GO:0042755=ISS, GO:0001764=ISS, GO:0051930=IEA} activation of cysteine-type endopeptidase activity involved in apoptotic process, axonogenesis, behavioral fear response, eating behavior, negative regulation of appetite, neuron migration, positive regulation of apoptotic process, positive regulation of cell proliferation, positive regulation of mitochondrial depolarization, positive regulation of peptidyl-tyrosine phosphorylation, positive regulation of protein oligomerization, protein kinase C-activating G-protein coupled receptor signaling pathway, regulation of sensory perception of pain, release of cytochrome c from mitochondria, signal transduction axon, axon hillock, axon initial segment, dendrite, extracellular region, extracellular space, perikaryon, terminal bouton hormone activity, neuropeptide hormone activity Human CCKAR Reactome UniProtKB {GO:0007631=PMID:8503909, GO:0005886=Reactome:REACT_22436, GO:0007584=PMID:8503909, GO:0005887=PMID:8343165, GO:0007586=PMID:8503909, GO:0007200=PMID:8343165, GO:0004951=GO_REF:0000002, GO:0030900=GO_REF:0000019, GO:0007409=GO_REF:0000019, GO:0001764=GO_REF:0000019, GO:0007204=PMID:8503909} P32238 Cholecystokinin receptor type A protein 20081212 {GO:0007631=TAS, GO:0005886=TAS, GO:0007584=TAS, GO:0005887=TAS, GO:0007586=TAS, GO:0007200=TAS, GO:0004951=IEA, GO:0030900=IEA, GO:0007409=IEA, GO:0001764=IEA, GO:0007204=TAS} axonogenesis, digestion, elevation of cytosolic calcium ion concentration, feeding behavior, forebrain development, neuron migration, phospholipase C-activating G-protein coupled receptor signaling pathway, response to nutrient integral to plasma membrane, plasma membrane cholecystokinin receptor activity Human CCKBR Reactome UniProtKB {GO:0015054=PMID:10913157, GO:0007631=PMID:7681836, GO:0008284=PMID:10913157, GO:0005886=Reactome:REACT_121113, GO:0008283=PMID:10400698, GO:0007586=PMID:7681836, GO:0007200=PMID:8455720, GO:0007204=PMID:10913157, GO:0046935=PMID:10400698, GO:0005887=PMID:10913157, GO:0004435=PMID:7681836, GO:0004951=PMID:7681836, GO:0016021=GO_REF:0000002, GO:0031741=PMID:8185642, GO:0007166=PMID:10913157, GO:0007600=PMID:7681836} P32239 Gastrin/cholecystokinin type B receptor protein 20120828 {GO:0015054=IDA, GO:0007631=TAS, GO:0008284=IDA, GO:0005886=TAS, GO:0008283=TAS, GO:0007586=TAS, GO:0007200=TAS, GO:0007204=IDA, GO:0046935=TAS, GO:0005887=IC, GO:0004435=TAS, GO:0004951=TAS, GO:0016021=IEA, GO:0031741=IDA, GO:0007166=NAS, GO:0007600=TAS} cell proliferation, cell surface receptor signaling pathway, digestion, elevation of cytosolic calcium ion concentration, feeding behavior, phospholipase C-activating G-protein coupled receptor signaling pathway, positive regulation of cell proliferation, sensory perception integral to membrane, integral to plasma membrane, plasma membrane 1-phosphatidylinositol-3-kinase regulator activity, cholecystokinin receptor activity, gastrin receptor activity, phosphatidylinositol phospholipase C activity, type B gastrin/cholecystokinin receptor binding Human CCL1 PINC UniProtKB {GO:0007165=PMID:9417093, GO:0008009=GO_REF:0000002, GO:0006955=GO_REF:0000002, GO:0006935=GO_REF:0000019, GO:0006874=PMID:9417093, GO:0016032=PMID:9417093, GO:0005615=GO_REF:0000037} P22362 C-C motif chemokine 1 protein 20030904 {GO:0007165=TAS, GO:0008009=IEA, GO:0006955=IEA, GO:0006935=IEA, GO:0006874=TAS, GO:0016032=TAS, GO:0005615=IEA} cellular calcium ion homeostasis, chemotaxis, immune response, signal transduction, viral reproduction extracellular space chemokine activity Human CCL11 BHF-UCL UniProtKB {GO:0032855=PMID:19525930, GO:0005615=GO_REF:0000019, GO:0006955=GO_REF:0000002, GO:0006954=PMID:10708591, GO:0006935=PMID:10706854, GO:0030838=PMID:19525930, GO:0007010=PMID:10072545, GO:0070670=GO_REF:0000019, GO:0007015=GO_REF:0000019, GO:0070371=GO_REF:0000019, GO:0007155=PMID:10201960, GO:0009314=PMID:10708591, GO:0008009=PMID:10072545, GO:0030335=PMID:19525930, GO:0006874=PMID:10415069, GO:0060763=GO_REF:0000019, GO:0005576=PMID:20041150, GO:0002544=GO_REF:0000019, GO:0009615=PMID:9558100, GO:0045766=GO_REF:0000019, GO:0007165=PMID:10706854, GO:0001938=PMID:19525930, GO:0002551=GO_REF:0000019, GO:0048245=PMID:10072545, GO:0006468=PMID:10706854, GO:0060444=GO_REF:0000019} P51671 Eotaxin protein 20120622 {GO:0032855=IDA, GO:0005615=IEA, GO:0006955=IEA, GO:0006954=TAS, GO:0006935=TAS, GO:0030838=IDA, GO:0007010=IDA, GO:0070670=IEA, GO:0007015=IEA, GO:0070371=IEA, GO:0007155=TAS, GO:0009314=TAS, GO:0008009=IDA, GO:0030335=IDA, GO:0006874=TAS, GO:0060763=IEA, GO:0005576=IDA, GO:0002544=IEA, GO:0009615=TAS, GO:0045766=IEA, GO:0007165=TAS, GO:0001938=IDA, GO:0002551=IEA, GO:0048245=IDA, GO:0006468=TAS, GO:0060444=IEA} ERK1 and ERK2 cascade, actin filament organization, branching involved in mammary gland duct morphogenesis, cell adhesion, cellular calcium ion homeostasis, chemotaxis, chronic inflammatory response, cytoskeleton organization, eosinophil chemotaxis, immune response, inflammatory response, mammary duct terminal end bud growth, mast cell chemotaxis, positive regulation of Rac GTPase activity, positive regulation of actin filament polymerization, positive regulation of angiogenesis, positive regulation of cell migration, positive regulation of endothelial cell proliferation, protein phosphorylation, response to interleukin-4, response to radiation, response to virus, signal transduction extracellular region, extracellular space chemokine activity Human CCL13 PINC UniProtKB {GO:0007165=PMID:9558100, GO:0008009=PMID:10072545, GO:0006955=GO_REF:0000002, GO:0006954=GO_REF:0000037, GO:0006935=PMID:9195948, GO:0007010=PMID:10072545, GO:0007267=PMID:9195948, GO:0006874=PMID:9195948, GO:0005102=PMID:9195948, GO:0048245=PMID:10072545, GO:0005576=GO_REF:0000002, GO:0005615=GO_REF:0000037} Q99616 C-C motif chemokine 13 protein 20030904 {GO:0007165=TAS, GO:0008009=IDA, GO:0006955=IEA, GO:0006954=IEA, GO:0006935=TAS, GO:0007010=IDA, GO:0007267=TAS, GO:0006874=TAS, GO:0005102=TAS, GO:0048245=IDA, GO:0005576=IEA, GO:0005615=IEA} cell-cell signaling, cellular calcium ion homeostasis, chemotaxis, cytoskeleton organization, eosinophil chemotaxis, immune response, inflammatory response, signal transduction extracellular region, extracellular space chemokine activity, receptor binding Human CCL14 PINC UniProtKB {GO:0008009=GO_REF:0000002, GO:0008284=PMID:8551235, GO:0006955=GO_REF:0000002, GO:0006874=PMID:8551235, GO:0005615=GO_REF:0000037} Q16627 C-C motif chemokine 14 protein 20030904 {GO:0008009=IEA, GO:0008284=TAS, GO:0006955=IEA, GO:0006874=TAS, GO:0005615=IEA} cellular calcium ion homeostasis, immune response, positive regulation of cell proliferation extracellular space chemokine activity Human CCL15 GOC UniProtKB {GO:0007165=PMID:9548457, GO:0008009=GO_REF:0000002, GO:0006955=GO_REF:0000002, GO:0006935=PMID:9600961, GO:0007267=PMID:9548457, GO:0006874=PMID:9346309, GO:0005102=PMID:9548457, GO:0005576=GO_REF:0000002, GO:0042056=PMID:15001559, GO:0008201=GO_REF:0000037, GO:0005615=GO_REF:0000037, GO:0050918=PMID:15001559} Q16663 C-C motif chemokine 15 protein 20130413 {GO:0007165=TAS, GO:0008009=IEA, GO:0006955=IEA, GO:0006935=TAS, GO:0007267=TAS, GO:0006874=TAS, GO:0005102=TAS, GO:0005576=IEA, GO:0042056=IDA, GO:0008201=IEA, GO:0005615=IEA, GO:0050918=IDA} cell-cell signaling, cellular calcium ion homeostasis, chemotaxis, immune response, positive chemotaxis, signal transduction extracellular region, extracellular space chemoattractant activity, chemokine activity, heparin binding, receptor binding Human CCL16 GOC UniProtKB {GO:0008009=GO_REF:0000002, GO:0006955=GO_REF:0000002, GO:0007154=PMID:9642106, GO:0006954=GO_REF:0000037, GO:0006935=PMID:9642106, GO:0007267=PMID:9642106, GO:0005576=Reactome:REACT_22289, GO:0042056=PMID:15001559, GO:0005615=GO_REF:0000037, GO:0050918=PMID:15001559} O15467 C-C motif chemokine 16 protein 20130413 {GO:0008009=IEA, GO:0006955=IEA, GO:0007154=TAS, GO:0006954=IEA, GO:0006935=TAS, GO:0007267=TAS, GO:0005576=TAS, GO:0042056=IDA, GO:0005615=IEA, GO:0050918=IDA} cell communication, cell-cell signaling, chemotaxis, immune response, inflammatory response, positive chemotaxis extracellular region, extracellular space chemoattractant activity, chemokine activity Human CCL17 Reactome UniProtKB {GO:0008009=GO_REF:0000002, GO:0006955=GO_REF:0000002, GO:0006954=GO_REF:0000037, GO:0007186=PMID:8702936, GO:0006935=GO_REF:0000037, GO:0007267=PMID:8702936, GO:0005102=PMID:9743322, GO:0005576=Reactome:REACT_21265, GO:0007275=PMID:8702936, GO:0005615=GO_REF:0000037} Q92583 C-C motif chemokine 17 protein 20091020 {GO:0008009=IEA, GO:0006955=IEA, GO:0006954=IEA, GO:0007186=TAS, GO:0006935=IEA, GO:0007267=TAS, GO:0005102=TAS, GO:0005576=TAS, GO:0007275=TAS, GO:0005615=IEA} G-protein coupled receptor signaling pathway, cell-cell signaling, chemotaxis, immune response, inflammatory response, multicellular organismal development extracellular region, extracellular space chemokine activity, receptor binding Human CCL18 PINC UniProtKB {GO:0009607=PMID:9233607, GO:0007165=PMID:9233607, GO:0008009=GO_REF:0000002, GO:0006955=GO_REF:0000002, GO:0007154=PMID:9192897, GO:0006954=GO_REF:0000037, GO:0006935=GO_REF:0000037, GO:0007267=PMID:9233607, GO:0005615=GO_REF:0000037} P55774 C-C motif chemokine 18 protein 20031119 {GO:0009607=TAS, GO:0007165=TAS, GO:0008009=IEA, GO:0006955=IEA, GO:0007154=TAS, GO:0006954=IEA, GO:0006935=IEA, GO:0007267=TAS, GO:0005615=IEA} cell communication, cell-cell signaling, chemotaxis, immune response, inflammatory response, response to biotic stimulus, signal transduction extracellular space chemokine activity Human CCL19 BHF-UCL UniProtKB {GO:0042346=PMID:15059845, GO:0014070=GO_REF:0000019, GO:0051897=PMID:15778365, GO:0048020=PMID:20002784, GO:0031295=GO_REF:0000024, GO:0071731=PMID:16249377, GO:0046330=PMID:15778365, GO:0032735=GO_REF:0000024, GO:0097029=GO_REF:0000024, GO:0005615=GO_REF:0000037, GO:2000147=PMID:15778365, GO:0045807=GO_REF:0000024, GO:0006955=GO_REF:0000002, GO:0006954=PMID:14592837, GO:0007154=PMID:9153236, GO:0050921=GO_REF:0000024, GO:0043552=PMID:15778365, GO:0034695=PMID:14592837, GO:0050718=GO_REF:0000024, GO:0043089=GO_REF:0000024, GO:0072610=GO_REF:0000024, GO:0042102=GO_REF:0000024, GO:0045860=PMID:14592837, GO:0060491=GO_REF:0000024, GO:0048469=GO_REF:0000024, GO:0070374=PMID:15778365, GO:0043123=PMID:15059845, GO:0001771=GO_REF:0000024, GO:0008009=PMID:15778365, GO:0051209=PMID:14592837, GO:0032760=GO_REF:0000024, GO:2000549=GO_REF:0000024, GO:0002408=PMID:14592837, GO:0002407=PMID:15778365, GO:0006874=PMID:9153236, GO:0005576=Reactome:REACT_22289, GO:0007257=GO_REF:0000024, GO:0002606=GO_REF:0000024, GO:0009615=PMID:9153236, GO:0031735=PMID:10706668, GO:0032320=GO_REF:0000024, GO:0010560=GO_REF:0000024, GO:2000107=PMID:15059845, GO:0048260=GO_REF:0000024, GO:0045627=GO_REF:0000024, GO:0090023=PMID:21051556, GO:0001768=PMID:12729902, GO:0031732=GO_REF:0000024} Q99731 C-C motif chemokine 19 protein 20120404 {GO:0042346=IDA, GO:0014070=IEA, GO:0051897=IDA, GO:0048020=IPI, GO:0031295=ISS, GO:0071731=IDA, GO:0046330=IDA, GO:0032735=ISS, GO:0097029=ISS, GO:0005615=IEA, GO:2000147=IDA, GO:0045807=ISS, GO:0006955=IEA, GO:0006954=NAS, GO:0007154=TAS, GO:0050921=ISS, GO:0043552=IDA, GO:0034695=IDA, GO:0050718=ISS, GO:0043089=ISS, GO:0072610=ISS, GO:0042102=ISS, GO:0045860=IDA, GO:0060491=ISS, GO:0048469=ISS, GO:0070374=IDA, GO:0043123=IDA, GO:0001771=ISS, GO:0008009=IDA, GO:0051209=IDA, GO:0032760=ISS, GO:2000549=ISS, GO:0002408=IDA, GO:0002407=IDA, GO:0006874=TAS, GO:0005576=TAS, GO:0007257=ISS, GO:0002606=ISS, GO:0009615=TAS, GO:0031735=IDA, GO:0032320=ISS, GO:0010560=ISS, GO:2000107=IDA, GO:0048260=ISS, GO:0045627=ISS, GO:0090023=IDA, GO:0001768=IDA, GO:0031732=ISS} T cell costimulation, activation of JUN kinase activity, cell communication, cell maturation, cellular calcium ion homeostasis, dendritic cell chemotaxis, establishment of T cell polarity, immune response, immunological synapse formation, inflammatory response, interleukin-12 secretion, mature dendritic cell differentiation, myeloid dendritic cell chemotaxis, negative regulation of leukocyte apoptotic process, positive regulation of Cdc42 GTPase activity, positive regulation of ERK1 and ERK2 cascade, positive regulation of I-kappaB kinase/NF-kappaB cascade, positive regulation of JNK cascade, positive regulation of NF-kappaB import into nucleus, positive regulation of Ras GTPase activity, positive regulation of T cell proliferation, positive regulation of T-helper 1 cell differentiation, positive regulation of cell motility, positive regulation of chemotaxis, positive regulation of dendritic cell antigen processing and presentation, positive regulation of dendritic cell dendrite assembly, positive regulation of endocytosis, positive regulation of glycoprotein biosynthetic process, positive regulation of interleukin-1 beta secretion, positive regulation of interleukin-12 production, positive regulation of neutrophil chemotaxis, positive regulation of phosphatidylinositol 3-kinase activity, positive regulation of protein kinase B signaling cascade, positive regulation of protein kinase activity, positive regulation of receptor-mediated endocytosis, positive regulation of tumor necrosis factor production, regulation of cell projection assembly, release of sequestered calcium ion into cytosol, response to nitric oxide, response to organic cyclic compound, response to prostaglandin E stimulus, response to virus extracellular region, extracellular space CCR chemokine receptor binding, CCR10 chemokine receptor binding, CCR7 chemokine receptor binding, chemokine activity Human UniProtKB:O70460 CCL2 BHF-UCL UniProtKB {GO:0009408=GO_REF:0000019, GO:0035684=GO_REF:0000024, GO:0019221=PMID:12207323, GO:0090265=GO_REF:0000019, GO:0005615=GO_REF:0000019, GO:0030968=Reactome:REACT_18356, GO:0006935=PMID:10623817, GO:0071356=GO_REF:0000024, GO:0031727=GO_REF:0000024, GO:0043025=GO_REF:0000019, GO:0009887=PMID:9364936, GO:0007179=GO_REF:0000019, GO:0010332=GO_REF:0000019, GO:0046677=GO_REF:0000019, GO:0008009=GO_REF:0000019, GO:0070098=GO_REF:0000019, GO:2000427=GO_REF:0000024, GO:0007568=GO_REF:0000019, GO:0030593=GO_REF:0000019, GO:0033552=GO_REF:0000019, GO:0060137=GO_REF:0000019, GO:0051384=GO_REF:0000019, GO:0071346=GO_REF:0000024, GO:0007186=PMID:10542238, GO:0007187=PMID:10770925, GO:0050870=GO_REF:0000024, GO:0050806=GO_REF:0000019, GO:0071347=GO_REF:0000024, GO:0010759=GO_REF:0000019, GO:0032570=GO_REF:0000019, GO:0048247=GO_REF:0000019, GO:0048246=PMID:12207323, GO:0006987=Reactome:REACT_18277, GO:0044267=Reactome:REACT_17015, GO:0045471=GO_REF:0000019, GO:0031100=GO_REF:0000019, GO:0019079=PMID:10985244, GO:0009617=PMID:16034137, GO:0005737=GO_REF:0000019, GO:0006955=GO_REF:0000002, GO:0006959=PMID:9548499, GO:0007010=PMID:10072545, GO:0007155=PMID:10198043, GO:0008201=GO_REF:0000019, GO:0043200=GO_REF:0000019, GO:0001666=GO_REF:0000019, GO:0048010=GO_REF:0000019, GO:0014823=GO_REF:0000019, GO:0019725=PMID:18334747, GO:0043066=PMID:12753088, GO:0042493=GO_REF:0000019, GO:0005102=PMID:10542238, GO:0006874=GO_REF:0000019, GO:0005576=PMID:20041150, GO:0001525=PMID:18334747, GO:0007259=PMID:9670957, GO:0043615=PMID:12271471, GO:0010574=GO_REF:0000019, GO:0002548=PMID:12207323, GO:0009612=GO_REF:0000019, GO:2000502=PMID:7545673, GO:0007165=PMID:10770925, GO:0071222=GO_REF:0000024, GO:0004672=PMID:9973507, GO:0001938=GO_REF:0000019, GO:0016525=GO_REF:0000019, GO:0006468=PMID:9670957, GO:0051770=GO_REF:0000024, GO:0007166=PMID:9548499} P13500 C-C motif chemokine 2 protein 20110225 {GO:0009408=IEA, GO:0035684=ISS, GO:0019221=IDA, GO:0090265=IEA, GO:0005615=IEA, GO:0030968=TAS, GO:0006935=TAS, GO:0071356=ISS, GO:0031727=ISS, GO:0043025=IEA, GO:0009887=TAS, GO:0007179=IEA, GO:0010332=IEA, GO:0046677=IEA, GO:0008009=IEA, GO:0070098=IEA, GO:2000427=ISS, GO:0007568=IEA, GO:0030593=IEA, GO:0033552=IEA, GO:0060137=IEA, GO:0051384=IEA, GO:0071346=ISS, GO:0007186=TAS, GO:0007187=TAS, GO:0050870=ISS, GO:0050806=IEA, GO:0071347=ISS, GO:0010759=IEA, GO:0032570=IEA, GO:0048247=IEA, GO:0048246=IDA, GO:0006987=TAS, GO:0044267=TAS, GO:0045471=IEA, GO:0031100=IEA, GO:0019079=TAS, GO:0009617=IEP, GO:0005737=IEA, GO:0006955=IEA, GO:0006959=TAS, GO:0007010=IDA, GO:0007155=TAS, GO:0008201=IEA, GO:0043200=IEA, GO:0001666=IEA, GO:0048010=IEA, GO:0014823=IEA, GO:0019725=TAS, GO:0043066=IDA, GO:0042493=IEA, GO:0005102=TAS, GO:0006874=IEA, GO:0005576=IDA, GO:0001525=TAS, GO:0007259=TAS, GO:0043615=IDA, GO:0010574=IEA, GO:0002548=IDA, GO:0009612=IEA, GO:2000502=IDA, GO:0007165=NAS, GO:0071222=ISS, GO:0004672=TAS, GO:0001938=IEA, GO:0016525=IEA, GO:0006468=TAS, GO:0051770=ISS, GO:0007166=TAS} G-protein coupled receptor signaling pathway, G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger, JAK-STAT cascade, activation of signaling protein activity involved in unfolded protein response, aging, angiogenesis, astrocyte cell migration, cell adhesion, cell surface receptor signaling pathway, cellular calcium ion homeostasis, cellular homeostasis, cellular protein metabolic process, cellular response to interferon-gamma, cellular response to interleukin-1, cellular response to lipopolysaccharide, cellular response to tumor necrosis factor, chemokine-mediated signaling pathway, chemotaxis, cytokine-mediated signaling pathway, cytoskeleton organization, endoplasmic reticulum unfolded protein response, helper T cell extravasation, humoral immune response, immune response, lymphocyte chemotaxis, macrophage chemotaxis, maternal process involved in parturition, monocyte chemotaxis, negative regulation of angiogenesis, negative regulation of apoptotic process, negative regulation of natural killer cell chemotaxis, neutrophil chemotaxis, organ morphogenesis, organ regeneration, positive regulation of T cell activation, positive regulation of apoptotic cell clearance, positive regulation of endothelial cell proliferation, positive regulation of immune complex clearance by monocytes and macrophages, positive regulation of macrophage chemotaxis, positive regulation of nitric-oxide synthase biosynthetic process, positive regulation of synaptic transmission, protein phosphorylation, regulation of vascular endothelial growth factor production, response to activity, response to amino acid stimulus, response to antibiotic, response to bacterium, response to drug, response to ethanol, response to gamma radiation, response to glucocorticoid stimulus, response to heat, response to hypoxia, response to mechanical stimulus, response to progesterone stimulus, response to vitamin B3, signal transduction, transforming growth factor beta receptor signaling pathway, vascular endothelial growth factor receptor signaling pathway, viral genome replication cytoplasm, extracellular region, extracellular space, neuronal cell body CCR2 chemokine receptor binding, chemokine activity, heparin binding, protein kinase activity, receptor binding Human UniProtKB:P10148 CCL20 Reactome UniProtKB {GO:0007165=PMID:9038201, GO:0008009=GO_REF:0000019, GO:0006955=GO_REF:0000002, GO:0006954=GO_REF:0000037, GO:0006935=GO_REF:0000037, GO:0007267=PMID:9038201, GO:0042466=GO_REF:0000019, GO:0005576=Reactome:REACT_22289, GO:0005615=GO_REF:0000037, GO:0042742=GO_REF:0000037} P78556 C-C motif chemokine 20 protein 20100217 {GO:0007165=TAS, GO:0008009=IEA, GO:0006955=IEA, GO:0006954=IEA, GO:0006935=IEA, GO:0007267=TAS, GO:0042466=IEA, GO:0005576=TAS, GO:0005615=IEA, GO:0042742=IEA} cell-cell signaling, chemokinesis, chemotaxis, defense response to bacterium, immune response, inflammatory response, signal transduction extracellular region, extracellular space chemokine activity Human CCL21 InterPro UniProtKB {GO:0051897=PMID:15778365, GO:0031295=GO_REF:0000024, GO:0007267=PMID:9235955, GO:0046330=PMID:15778365, GO:0051491=PMID:15569314, GO:0005615=GO_REF:0000037, GO:0097026=GO_REF:0000024, GO:2000147=PMID:15778365, GO:0031529=PMID:15569314, GO:0006955=GO_REF:0000002, GO:0006954=PMID:14592837, GO:0050921=GO_REF:0000024, GO:0034695=PMID:14592837, GO:0030838=PMID:11242036, GO:0043552=PMID:15778365, GO:0045860=PMID:15059845, GO:0031274=PMID:11242036, GO:0048469=GO_REF:0000024, GO:0070374=PMID:12729902, GO:0043123=PMID:15059845, GO:0001771=GO_REF:0000024, GO:0008009=GO_REF:0000002, GO:0051209=PMID:14592837, GO:2000529=PMID:14592837, GO:2000548=GO_REF:0000024, GO:0002407=PMID:15778365, GO:0033630=PMID:15569314, GO:0005576=GO_REF:0000002, GO:0032862=PMID:15778365, GO:0002606=GO_REF:0000024, GO:0010560=GO_REF:0000024, GO:2000107=PMID:15059845, GO:0048260=GO_REF:0000024, GO:0090023=PMID:21051556, GO:0001768=PMID:12729902, GO:0035759=PMID:15569314, GO:0001954=PMID:15569314, GO:0031732=GO_REF:0000024} Q5VZ73 C-C motif chemokine 21 protein 20130413 {GO:0051897=IDA, GO:0031295=ISS, GO:0007267=TAS, GO:0046330=IDA, GO:0051491=IDA, GO:0005615=IEA, GO:0097026=ISS, GO:2000147=IDA, GO:0031529=IDA, GO:0006955=IEA, GO:0006954=NAS, GO:0050921=ISS, GO:0034695=IDA, GO:0030838=IDA, GO:0043552=IDA, GO:0045860=IDA, GO:0031274=IDA, GO:0048469=ISS, GO:0070374=IDA, GO:0043123=IDA, GO:0001771=ISS, GO:0008009=IEA, GO:0051209=IDA, GO:2000529=IDA, GO:2000548=ISS, GO:0002407=IDA, GO:0033630=IDA, GO:0005576=IEA, GO:0032862=IDA, GO:0002606=ISS, GO:0010560=ISS, GO:2000107=IDA, GO:0048260=ISS, GO:0090023=IDA, GO:0001768=IDA, GO:0035759=IDA, GO:0001954=IDA, GO:0031732=ISS} T cell costimulation, activation of Rho GTPase activity, cell maturation, cell-cell signaling, dendritic cell chemotaxis, dendritic cell dendrite assembly, establishment of T cell polarity, immune response, immunological synapse formation, inflammatory response, mesangial cell-matrix adhesion, negative regulation of dendritic cell dendrite assembly, negative regulation of leukocyte apoptotic process, positive regulation of ERK1 and ERK2 cascade, positive regulation of I-kappaB kinase/NF-kappaB cascade, positive regulation of JNK cascade, positive regulation of actin filament polymerization, positive regulation of cell adhesion mediated by integrin, positive regulation of cell motility, positive regulation of cell-matrix adhesion, positive regulation of chemotaxis, positive regulation of dendritic cell antigen processing and presentation, positive regulation of filopodium assembly, positive regulation of glycoprotein biosynthetic process, positive regulation of myeloid dendritic cell chemotaxis, positive regulation of neutrophil chemotaxis, positive regulation of phosphatidylinositol 3-kinase activity, positive regulation of protein kinase B signaling cascade, positive regulation of protein kinase activity, positive regulation of pseudopodium assembly, positive regulation of receptor-mediated endocytosis, release of sequestered calcium ion into cytosol, response to prostaglandin E stimulus, ruffle organization extracellular region, extracellular space CCR7 chemokine receptor binding, chemokine activity Human InterPro:IPR001811 CCL22 Reactome UniProtKB {GO:0007165=PMID:9743322, GO:0008009=GO_REF:0000002, GO:0006955=GO_REF:0000002, GO:0006954=PMID:9151897, GO:0006935=GO_REF:0000037, GO:0007267=PMID:9151897, GO:0005576=Reactome:REACT_21265, GO:0009615=PMID:9381181, GO:0005615=GO_REF:0000037} O00626 C-C motif chemokine 22 protein 20091020 {GO:0007165=TAS, GO:0008009=IEA, GO:0006955=IEA, GO:0006954=TAS, GO:0006935=IEA, GO:0007267=TAS, GO:0005576=TAS, GO:0009615=TAS, GO:0005615=IEA} cell-cell signaling, chemotaxis, immune response, inflammatory response, response to virus, signal transduction extracellular region, extracellular space chemokine activity Human CCL23 Reactome UniProtKB {GO:0008009=PMID:10660125, GO:0008285=PMID:9104803, GO:0006874=PMID:9886417, GO:0007267=PMID:9104803, GO:0005576=Reactome:REACT_22436, GO:0005615=GO_REF:0000037, GO:0002548=PMID:10660125, GO:0007165=PMID:9886417, GO:0006955=GO_REF:0000002, GO:0006954=GO_REF:0000037, GO:0006935=PMID:9104803, GO:0007186=PMID:9886417, GO:2001264=PMID:10660125, GO:0008201=GO_REF:0000037} P55773 C-C motif chemokine 23 protein 20091023 {GO:0008009=IDA, GO:0008285=TAS, GO:0006874=TAS, GO:0007267=TAS, GO:0005576=TAS, GO:0005615=IEA, GO:0002548=IC, GO:0007165=NAS, GO:0006955=IEA, GO:0006954=IEA, GO:0006935=TAS, GO:0007186=TAS, GO:2001264=IDA, GO:0008201=IEA} G-protein coupled receptor signaling pathway, cell-cell signaling, cellular calcium ion homeostasis, chemotaxis, immune response, inflammatory response, monocyte chemotaxis, negative regulation of C-C chemokine binding, negative regulation of cell proliferation, signal transduction extracellular region, extracellular space chemokine activity, heparin binding Human CCL24 BHF-UCL UniProtKB {GO:0008009=PMID:10072545, GO:0030335=PMID:19525930, GO:0008360=PMID:10072545, GO:0007267=PMID:9104803, GO:0032855=PMID:19525930, GO:0005615=GO_REF:0000037, GO:0045766=GO_REF:0000019, GO:0007165=PMID:9104803, GO:0006955=GO_REF:0000002, GO:0006954=GO_REF:0000037, GO:0030838=PMID:19525930, GO:0006935=PMID:9104803, GO:0001938=PMID:19525930, GO:0050729=GO_REF:0000019, GO:0007010=PMID:10072545, GO:0048245=PMID:10072545} O00175 C-C motif chemokine 24 protein 20091106 {GO:0008009=IDA, GO:0030335=IDA, GO:0008360=IDA, GO:0007267=TAS, GO:0032855=IDA, GO:0005615=IEA, GO:0045766=IEA, GO:0007165=TAS, GO:0006955=IEA, GO:0006954=IEA, GO:0030838=IDA, GO:0006935=TAS, GO:0001938=IDA, GO:0050729=IEA, GO:0007010=IDA, GO:0048245=IDA} cell-cell signaling, chemotaxis, cytoskeleton organization, eosinophil chemotaxis, immune response, inflammatory response, positive regulation of Rac GTPase activity, positive regulation of actin filament polymerization, positive regulation of angiogenesis, positive regulation of cell migration, positive regulation of endothelial cell proliferation, positive regulation of inflammatory response, regulation of cell shape, signal transduction extracellular space chemokine activity Human CCL25 BHF-UCL UniProtKB {GO:0031735=PMID:10706668, GO:0008009=GO_REF:0000019, GO:0006955=GO_REF:0000002, GO:0006954=GO_REF:0000037, GO:0007186=PMID:10544196, GO:0005179=PMID:9285413, GO:0006935=GO_REF:0000019, GO:0005576=Reactome:REACT_22289, GO:0050900=GO_REF:0000019, GO:0005615=GO_REF:0000037, GO:0007166=PMID:10640743} O15444 C-C motif chemokine 25 protein 20110329 {GO:0031735=IDA, GO:0008009=IEA, GO:0006955=IEA, GO:0006954=IEA, GO:0007186=TAS, GO:0005179=TAS, GO:0006935=IEA, GO:0005576=TAS, GO:0050900=IEA, GO:0005615=IEA, GO:0007166=TAS} G-protein coupled receptor signaling pathway, cell surface receptor signaling pathway, chemotaxis, immune response, inflammatory response, leukocyte migration extracellular region, extracellular space CCR10 chemokine receptor binding, chemokine activity, hormone activity Human CCL26 BHF-UCL UniProtKB {GO:0007165=PMID:10373330, GO:0008009=GO_REF:0000002, GO:0006955=GO_REF:0000002, GO:0030335=PMID:19525930, GO:0006954=GO_REF:0000037, GO:0030838=PMID:19525930, GO:0001938=PMID:19525930, GO:0006935=GO_REF:0000037, GO:0007267=PMID:10373330, GO:0032855=PMID:19525930, GO:0005615=GO_REF:0000037} Q9Y258 C-C motif chemokine 26 protein 20091106 {GO:0007165=NAS, GO:0008009=IEA, GO:0006955=IEA, GO:0030335=IDA, GO:0006954=IEA, GO:0030838=IDA, GO:0001938=IDA, GO:0006935=IEA, GO:0007267=TAS, GO:0032855=IDA, GO:0005615=IEA} cell-cell signaling, chemotaxis, immune response, inflammatory response, positive regulation of Rac GTPase activity, positive regulation of actin filament polymerization, positive regulation of cell migration, positive regulation of endothelial cell proliferation, signal transduction extracellular space chemokine activity Human CCL27 Reactome UniProtKB {GO:0008009=GO_REF:0000002, GO:0006955=GO_REF:0000002, GO:0006935=PMID:10588729, GO:0007267=PMID:10588729, GO:0005576=Reactome:REACT_22289, GO:0005615=GO_REF:0000037} Q9Y4X3 C-C motif chemokine 27 protein 20080717 {GO:0008009=IEA, GO:0006955=IEA, GO:0006935=TAS, GO:0007267=TAS, GO:0005576=TAS, GO:0005615=IEA} cell-cell signaling, chemotaxis, immune response extracellular region, extracellular space chemokine activity Human CCL28 Reactome UniProtKB {GO:0008009=PMID:10781587, GO:0006955=GO_REF:0000002, GO:0006935=PMID:10781587, GO:0005576=Reactome:REACT_22289, GO:0005615=GO_REF:0000037, GO:0007204=GO_REF:0000019} Q9NRJ3 C-C motif chemokine 28 protein 20080717 {GO:0008009=TAS, GO:0006955=IEA, GO:0006935=TAS, GO:0005576=TAS, GO:0005615=IEA, GO:0007204=IEA} chemotaxis, elevation of cytosolic calcium ion concentration, immune response extracellular region, extracellular space chemokine activity Human CCL3 GOC UniProtKB {GO:0005515=PMID:21784977, GO:0019722=PMID:10072545, GO:0051928=PMID:15764707, GO:0007267=PMID:10679098, GO:0006887=PMID:10734056, GO:0005615=PMID:20167378, GO:0010818=PMID:10706735, GO:0005829=PMID:19523456, GO:0050850=PMID:10679098, GO:0005622=PMID:10072545, GO:0031726=PMID:15764707, GO:0005737=PMID:21784977, GO:0043525=GO_REF:0000024, GO:0006954=PMID:10706735, GO:0006935=PMID:10679098, GO:0050718=GO_REF:0000024, GO:0007010=PMID:10072545, GO:0007610=PMID:20167378, GO:0006816=PMID:10734056, GO:0008009=PMID:10660125, GO:0030335=PMID:10706735, GO:0032760=GO_REF:0000024, GO:0023052=PMID:12032188, GO:0030593=PMID:10706735, GO:0006874=PMID:10072545, GO:0009636=PMID:10841574, GO:0071621=PMID:10706735, GO:0005576=PMID:20041150, GO:0014808=PMID:19523456, GO:0045671=PMID:21403648, GO:0042056=PMID:10660125, GO:0043308=PMID:10706735, GO:0043615=GO_REF:0000024, GO:0001649=PMID:21403648, GO:0050918=PMID:15001559, GO:0002548=PMID:10660125, GO:0016310=PMID:21403648, GO:0016004=PMID:10734056, GO:0050729=GO_REF:0000024, GO:0048245=PMID:10072545, GO:0070723=PMID:19523456, GO:0006468=PMID:10734056, GO:0004698=PMID:15764707, GO:0048247=PMID:10706735, GO:0048246=GO_REF:0000024, GO:0031730=PMID:8699119, GO:0051930=PMID:15764707, GO:2000503=PMID:7545673} P10147 C-C motif chemokine 3 protein 20130413 {GO:0005515=IPI, GO:0019722=IDA, GO:0051928=IDA, GO:0007267=IDA, GO:0006887=IDA, GO:0005615=IDA, GO:0010818=IDA, GO:0005829=IDA, GO:0050850=IMP, GO:0005622=IDA, GO:0031726=IPI, GO:0005737=IDA, GO:0043525=ISS, GO:0006954=IDA, GO:0006935=IDA, GO:0050718=ISS, GO:0007010=IDA, GO:0007610=IDA, GO:0006816=IDA, GO:0008009=IDA, GO:0030335=IDA, GO:0032760=ISS, GO:0023052=IEP, GO:0030593=IDA, GO:0006874=IDA, GO:0009636=IDA, GO:0071621=IDA, GO:0005576=IDA, GO:0014808=IDA, GO:0045671=IDA, GO:0042056=IDA, GO:0043308=IDA, GO:0043615=ISS, GO:0001649=IEP, GO:0050918=IDA, GO:0002548=IC, GO:0016310=IDA, GO:0016004=IDA, GO:0050729=ISS, GO:0048245=IDA, GO:0070723=IDA, GO:0006468=IDA, GO:0004698=IDA, GO:0048247=IDA, GO:0048246=ISS, GO:0031730=IPI, GO:0051930=IDA, GO:2000503=IDA} T cell chemotaxis, astrocyte cell migration, behavior, calcium ion transport, calcium-mediated signaling, cell-cell signaling, cellular calcium ion homeostasis, chemotaxis, cytoskeleton organization, eosinophil chemotaxis, eosinophil degranulation, exocytosis, granulocyte chemotaxis, inflammatory response, lymphocyte chemotaxis, macrophage chemotaxis, monocyte chemotaxis, negative regulation of osteoclast differentiation, neutrophil chemotaxis, osteoblast differentiation, phosphorylation, positive chemotaxis, positive regulation of calcium ion transport, positive regulation of calcium-mediated signaling, positive regulation of cell migration, positive regulation of inflammatory response, positive regulation of interleukin-1 beta secretion, positive regulation of natural killer cell chemotaxis, positive regulation of neuron apoptotic process, positive regulation of tumor necrosis factor production, protein phosphorylation, regulation of sensory perception of pain, release of sequestered calcium ion into cytosol by sarcoplasmic reticulum, response to cholesterol, response to toxic substance, signaling cytoplasm, cytosol, extracellular region, extracellular space, intracellular CCR1 chemokine receptor binding, CCR5 chemokine receptor binding, calcium-dependent protein kinase C activity, chemoattractant activity, chemokine activity, phospholipase activator activity, protein binding Human CCL3L1 Reactome UniProtKB {GO:0008009=GO_REF:0000029, GO:0006955=GO_REF:0000002, GO:0006954=PMID:1694014, GO:0008285=PMID:2271120, GO:0006935=GO_REF:0000029, GO:0005576=Reactome:REACT_21265, GO:0005615=GO_REF:0000037} P16619 C-C motif chemokine 3-like 1 protein 20091020 {GO:0008009=NAS, GO:0006955=IEA, GO:0006954=TAS, GO:0008285=TAS, GO:0006935=NAS, GO:0005576=TAS, GO:0005615=IEA} chemotaxis, immune response, inflammatory response, negative regulation of cell proliferation extracellular region, extracellular space chemokine activity Human CCL3L3 null null {} null null null null {} null null null CCL4 Reactome UniProtKB {GO:0008009=GO_REF:0000002, GO:0051928=PMID:8699119, GO:0007267=PMID:2521882, GO:0009636=PMID:10841574, GO:0006928=PMID:9759849, GO:0005576=Reactome:REACT_21265, GO:0009615=PMID:9743377, GO:0005615=GO_REF:0000037, GO:0005125=PMID:2462251, GO:0050850=PMID:10679098, GO:0031726=PMID:7545673, GO:0007165=PMID:9558100, GO:0006955=GO_REF:0000002, GO:0007163=PMID:9759849, GO:0006954=GO_REF:0000037, GO:0006935=GO_REF:0000037, GO:0007155=PMID:10929056, GO:0031730=PMID:10679098, GO:2000503=PMID:7545673} P13236 C-C motif chemokine 4 protein 20091020 {GO:0008009=IEA, GO:0051928=IDA, GO:0007267=TAS, GO:0009636=IDA, GO:0006928=TAS, GO:0005576=TAS, GO:0009615=TAS, GO:0005615=IEA, GO:0005125=TAS, GO:0050850=IMP, GO:0031726=IPI, GO:0007165=TAS, GO:0006955=IEA, GO:0007163=TAS, GO:0006954=IEA, GO:0006935=IEA, GO:0007155=TAS, GO:0031730=IPI, GO:2000503=IDA} cell adhesion, cell-cell signaling, cellular component movement, chemotaxis, establishment or maintenance of cell polarity, immune response, inflammatory response, positive regulation of calcium ion transport, positive regulation of calcium-mediated signaling, positive regulation of natural killer cell chemotaxis, response to toxic substance, response to virus, signal transduction extracellular region, extracellular space CCR1 chemokine receptor binding, CCR5 chemokine receptor binding, chemokine activity, cytokine activity Human CCL5 GOC UniProtKB {GO:0005515=PMID:8699119, GO:0051928=PMID:8699119, GO:0070233=PMID:10488085, GO:0070234=PMID:10488085, GO:0043621=PMID:10488085, GO:0006887=PMID:10734056, GO:0005615=GO_REF:0000037, GO:0043623=PMID:18337562, GO:0042803=PMID:10488085, GO:0031726=PMID:10910894, GO:0030298=PMID:10488085, GO:0006935=PMID:1380064, GO:0070100=PMID:8631850, GO:0031729=PMID:9417081, GO:0045070=PMID:10488085, GO:0045071=PMID:10490959, GO:0031584=PMID:9469451, GO:0008009=PMID:1699135, GO:0070098=PMID:18337562, GO:0042531=PMID:9417081, GO:0045744=PMID:10734056, GO:0030335=PMID:7545673, GO:0009636=PMID:10841574, GO:0014068=PMID:7544376, GO:0042056=PMID:15001559, GO:0045785=PMID:10910894, GO:0016004=PMID:10734056, GO:0045089=PMID:21148810, GO:0048245=PMID:16778803, GO:0010759=PMID:16778803, GO:0048246=PMID:18337562, GO:0090026=PMID:19779041, GO:0042119=PMID:10488085, GO:0031730=PMID:9139699, GO:0007267=PMID:8558019, GO:0014911=PMID:21297082, GO:0006955=GO_REF:0000002, GO:0005737=GO_REF:0000019, GO:0002676=PMID:10488085, GO:0042102=PMID:18832695, GO:0007159=PMID:8558019, GO:0045948=PMID:18337562, GO:0006816=PMID:10734056, GO:0010535=PMID:11278738, GO:0050863=PMID:10488085, GO:0051262=PMID:10488085, GO:0010820=PMID:7544376, GO:0002407=PMID:18337562, GO:0006874=PMID:10734056, GO:0005576=Reactome:REACT_22289, GO:0042379=PMID:7517217, GO:0034112=PMID:10488085, GO:0033634=PMID:8558019, GO:2000110=GO_REF:0000019, GO:0009615=PMID:10488085, GO:0048661=PMID:21297082, GO:0050918=PMID:15001559, GO:0046427=PMID:11278738, GO:0002548=PMID:10660125, GO:0046817=PMID:8631850, GO:0004435=PMID:10734056, GO:0006468=PMID:10734056, GO:0031328=PMID:18337562, GO:0042327=PMID:18337562, GO:2000503=PMID:7545673} P13501 C-C motif chemokine 5 protein 20130413 {GO:0005515=IPI, GO:0051928=IDA, GO:0070233=IDA, GO:0070234=IDA, GO:0043621=IDA, GO:0006887=IDA, GO:0005615=IEA, GO:0043623=IDA, GO:0042803=IDA, GO:0031726=IDA, GO:0030298=IDA, GO:0006935=NAS, GO:0070100=IDA, GO:0031729=TAS, GO:0045070=TAS, GO:0045071=IDA, GO:0031584=IDA, GO:0008009=IDA, GO:0070098=TAS, GO:0042531=IDA, GO:0045744=IDA, GO:0030335=IDA, GO:0009636=IDA, GO:0014068=IDA, GO:0042056=IDA, GO:0045785=IDA, GO:0016004=IDA, GO:0045089=TAS, GO:0048245=IDA, GO:0010759=IDA, GO:0048246=TAS, GO:0090026=IDA, GO:0042119=IDA, GO:0031730=IPI, GO:0007267=IDA, GO:0014911=IDA, GO:0006955=IEA, GO:0005737=IEA, GO:0002676=TAS, GO:0042102=IDA, GO:0007159=IDA, GO:0045948=NAS, GO:0006816=IDA, GO:0010535=TAS, GO:0050863=IDA, GO:0051262=IDA, GO:0010820=IDA, GO:0002407=TAS, GO:0006874=IDA, GO:0005576=TAS, GO:0042379=IPI, GO:0034112=IDA, GO:0033634=IDA, GO:2000110=IEA, GO:0009615=TAS, GO:0048661=IDA, GO:0050918=IDA, GO:0046427=TAS, GO:0002548=IC, GO:0046817=IDA, GO:0004435=IDA, GO:0006468=IDA, GO:0031328=IDA, GO:0042327=IDA, GO:2000503=IDA} activation of phospholipase D activity, calcium ion transport, cell-cell signaling, cellular calcium ion homeostasis, cellular protein complex assembly, chemokine-mediated signaling pathway, chemotaxis, dendritic cell chemotaxis, eosinophil chemotaxis, exocytosis, immune response, leukocyte cell-cell adhesion, macrophage chemotaxis, monocyte chemotaxis, negative regulation of G-protein coupled receptor protein signaling pathway, negative regulation of T cell apoptotic process, negative regulation of chemokine-mediated signaling pathway, negative regulation of macrophage apoptotic process, negative regulation of viral genome replication, neutrophil activation, positive chemotaxis, positive regulation of JAK-STAT cascade, positive regulation of T cell apoptotic process, positive regulation of T cell chemotaxis, positive regulation of T cell proliferation, positive regulation of activation of JAK2 kinase activity, positive regulation of calcium ion transport, positive regulation of cell adhesion, positive regulation of cell migration, positive regulation of cell-cell adhesion mediated by integrin, positive regulation of cellular biosynthetic process, positive regulation of homotypic cell-cell adhesion, positive regulation of innate immune response, positive regulation of macrophage chemotaxis, positive regulation of monocyte chemotaxis, positive regulation of natural killer cell chemotaxis, positive regulation of phosphatidylinositol 3-kinase cascade, positive regulation of phosphorylation, positive regulation of smooth muscle cell migration, positive regulation of smooth muscle cell proliferation, positive regulation of translational initiation, positive regulation of tyrosine phosphorylation of STAT protein, positive regulation of viral genome replication, protein phosphorylation, protein tetramerization, regulation of T cell activation, regulation of chronic inflammatory response, response to toxic substance, response to virus cytoplasm, extracellular region, extracellular space CCR1 chemokine receptor binding, CCR4 chemokine receptor binding, CCR5 chemokine receptor binding, chemoattractant activity, chemokine activity, chemokine receptor antagonist activity, chemokine receptor binding, phosphatidylinositol phospholipase C activity, phospholipase activator activity, protein binding, protein homodimerization activity, protein self-association, receptor signaling protein tyrosine kinase activator activity Human CCL7 Reactome UniProtKB {GO:0008009=PMID:10072545, GO:0030335=PMID:7545673, GO:0007267=PMID:7916328, GO:0006874=PMID:10770925, GO:0005576=Reactome:REACT_21265, GO:0005615=GO_REF:0000037, GO:0002548=PMID:10660125, GO:0031726=PMID:7545673, GO:0007165=PMID:10770925, GO:0006955=GO_REF:0000002, GO:0071361=GO_REF:0000019, GO:0006954=GO_REF:0000037, GO:0006935=PMID:9780207, GO:0031727=GO_REF:0000019, GO:0007010=PMID:10072545, GO:0048245=PMID:10072545, GO:0008201=GO_REF:0000037, GO:0010332=GO_REF:0000019, GO:2000503=PMID:7545673} P80098 C-C motif chemokine 7 protein 20091020 {GO:0008009=IDA, GO:0030335=IDA, GO:0007267=TAS, GO:0006874=TAS, GO:0005576=TAS, GO:0005615=IEA, GO:0002548=IC, GO:0031726=IPI, GO:0007165=TAS, GO:0006955=IEA, GO:0071361=IEA, GO:0006954=IEA, GO:0006935=TAS, GO:0031727=IEA, GO:0007010=IDA, GO:0048245=IDA, GO:0008201=IEA, GO:0010332=IEA, GO:2000503=IDA} cell-cell signaling, cellular calcium ion homeostasis, cellular response to ethanol, chemotaxis, cytoskeleton organization, eosinophil chemotaxis, immune response, inflammatory response, monocyte chemotaxis, positive regulation of cell migration, positive regulation of natural killer cell chemotaxis, response to gamma radiation, signal transduction extracellular region, extracellular space CCR1 chemokine receptor binding, CCR2 chemokine receptor binding, chemokine activity, heparin binding Human CCL8 GOC UniProtKB {GO:0008009=GO_REF:0000002, GO:0006874=PMID:10734056, GO:0007267=PMID:10734056, GO:0006887=PMID:10734056, GO:0009615=PMID:9468473, GO:0005615=GO_REF:0000037, GO:0007165=PMID:9119400, GO:0006955=GO_REF:0000002, GO:0006954=GO_REF:0000037, GO:0016004=PMID:10734056, GO:0006935=GO_REF:0000037, GO:0006468=PMID:10734056, GO:0006816=PMID:10734056, GO:0008201=GO_REF:0000037} P80075 C-C motif chemokine 8 protein 20130413 {GO:0008009=IEA, GO:0006874=IDA, GO:0007267=IDA, GO:0006887=IDA, GO:0009615=TAS, GO:0005615=IEA, GO:0007165=TAS, GO:0006955=IEA, GO:0006954=IEA, GO:0016004=IDA, GO:0006935=IEA, GO:0006468=IDA, GO:0006816=IDA, GO:0008201=IEA} calcium ion transport, cell-cell signaling, cellular calcium ion homeostasis, chemotaxis, exocytosis, immune response, inflammatory response, protein phosphorylation, response to virus, signal transduction extracellular space chemokine activity, heparin binding, phospholipase activator activity Human CCM2 IntAct UniProtKB {GO:0005515=PMID:17657516, GO:0005737=PMID:16037064, GO:0061154=PMID:19151727, GO:0007229=PMID:16037064, GO:0051403=PMID:16037064, GO:0001570=PMID:14740320} Q9BSQ5 Malcavernin protein 20130415 {GO:0005515=IPI, GO:0005737=IDA, GO:0061154=IMP, GO:0007229=TAS, GO:0051403=TAS, GO:0001570=IMP} endothelial tube morphogenesis, integrin-mediated signaling pathway, stress-activated MAPK cascade, vasculogenesis cytoplasm protein binding Human UniProtKB:Q9BUL8 CCNA1 IntAct UniProtKB {GO:0005515=PMID:15232106, GO:0019901=GO_REF:0000002, GO:0000079=GO_REF:0000002, GO:0007283=PMID:9843212, GO:0005829=PMID:9041194, GO:0007067=GO_REF:0000037, GO:0000082=Reactome:REACT_1783, GO:0000083=Reactome:REACT_683, GO:0000086=Reactome:REACT_2203, GO:0015630=GO_REF:0000054, GO:0005654=Reactome:REACT_22145, GO:0000278=Reactome:REACT_152, GO:0007141=PMID:9843212, GO:0051301=GO_REF:0000037} P78396 Cyclin-A1 protein 20130415 {GO:0005515=IPI, GO:0019901=IEA, GO:0000079=IEA, GO:0007283=TAS, GO:0005829=TAS, GO:0007067=IEA, GO:0000082=TAS, GO:0000083=TAS, GO:0000086=TAS, GO:0015630=IDA, GO:0005654=TAS, GO:0000278=TAS, GO:0007141=TAS, GO:0051301=IEA} G1/S transition of mitotic cell cycle, G2/M transition of mitotic cell cycle, cell division, male meiosis I, mitosis, mitotic cell cycle, regulation of cyclin-dependent protein serine/threonine kinase activity, regulation of transcription involved in G1/S phase of mitotic cell cycle, spermatogenesis cytosol, microtubule cytoskeleton, nucleoplasm protein binding, protein kinase binding Human UniProtKB:P38936 CCNA2 BHF-UCL UniProtKB {GO:0005515=PMID:23455922, GO:0007095=PMID:1312467, GO:0019901=GO_REF:0000019, GO:0007265=PMID:9054499, GO:0005634=PMID:16109376, GO:0000079=GO_REF:0000002, GO:0007067=GO_REF:0000037, GO:0005737=GO_REF:0000039, GO:0001939=GO_REF:0000019, GO:0000086=Reactome:REACT_2203, GO:0005654=Reactome:REACT_1627, GO:0001940=GO_REF:0000019, GO:0045893=GO_REF:0000019, GO:0000278=Reactome:REACT_152, GO:0051301=GO_REF:0000037} P20248 Cyclin-A2 protein 20091126 {GO:0005515=IPI, GO:0007095=TAS, GO:0019901=IEA, GO:0007265=IEP, GO:0005634=IDA, GO:0000079=IEA, GO:0007067=IEA, GO:0005737=IEA, GO:0001939=IEA, GO:0000086=TAS, GO:0005654=TAS, GO:0001940=IEA, GO:0045893=IEA, GO:0000278=TAS, GO:0051301=IEA} G2/M transition of mitotic cell cycle, Ras protein signal transduction, cell division, mitosis, mitotic G2 DNA damage checkpoint, mitotic cell cycle, positive regulation of transcription, DNA-dependent, regulation of cyclin-dependent protein serine/threonine kinase activity cytoplasm, female pronucleus, male pronucleus, nucleoplasm, nucleus protein binding, protein kinase binding Human CCNB1 UniProtKB UniProtKB {GO:0060045=GO_REF:0000019, GO:0007077=Reactome:REACT_160255, GO:0005515=PMID:21952639, GO:0000236=PMID:18195732, GO:0046680=GO_REF:0000019, GO:0001556=GO_REF:0000019, GO:0007283=GO_REF:0000019, GO:0005113=PMID:11331587, GO:0071398=GO_REF:0000019, GO:0016301=GO_REF:0000019, GO:0071283=GO_REF:0000019, GO:0005813=PMID:12524548, GO:0019901=GO_REF:0000002, GO:0001701=GO_REF:0000019, GO:0007049=GO_REF:0000038, GO:0000922=PMID:18195732, GO:0045931=PMID:18195732, GO:0055015=GO_REF:0000019, GO:0000075=Reactome:REACT_1538, GO:0005654=Reactome:REACT_150132, GO:0007080=PMID:18195732, GO:0000278=Reactome:REACT_152, GO:0031442=GO_REF:0000019, GO:0051301=GO_REF:0000038, GO:0043148=PMID:18195732, GO:0005634=GO_REF:0000002, GO:0000079=GO_REF:0000002, GO:0042246=GO_REF:0000019, GO:0031145=Reactome:REACT_6828, GO:0005829=Reactome:REACT_160217, GO:0005737=PMID:11331587, GO:0000082=Reactome:REACT_1783, GO:0000088=Reactome:REACT_765, GO:0000086=Reactome:REACT_2203, GO:0000087=Reactome:REACT_910, GO:0071174=PMID:18195732, GO:0060623=GO_REF:0000019, GO:0051987=PMID:18195732, GO:0042493=GO_REF:0000019, GO:0051437=Reactome:REACT_6904, GO:0071456=GO_REF:0000019, GO:0048565=GO_REF:0000019, GO:0051439=Reactome:REACT_6837, GO:0009612=GO_REF:0000019, GO:0071407=GO_REF:0000019, GO:0033129=GO_REF:0000019, GO:0006461=GO_REF:0000019, GO:0016020=GO_REF:0000019, GO:0000942=PMID:18195732, GO:0010629=GO_REF:0000019, GO:0001933=GO_REF:0000019, GO:0006468=GO_REF:0000019} Q5TZP9 Cyclin B1 protein 20130413 {GO:0060045=IEA, GO:0007077=TAS, GO:0005515=IPI, GO:0000236=IDA, GO:0046680=IEA, GO:0001556=IEA, GO:0007283=IEA, GO:0005113=IPI, GO:0071398=IEA, GO:0016301=IEA, GO:0071283=IEA, GO:0005813=IDA, GO:0019901=IEA, GO:0001701=IEA, GO:0007049=IEA, GO:0000922=IDA, GO:0045931=IMP, GO:0055015=IEA, GO:0000075=TAS, GO:0005654=TAS, GO:0007080=IMP, GO:0000278=TAS, GO:0031442=IEA, GO:0051301=IEA, GO:0043148=IMP, GO:0005634=IEA, GO:0000079=IEA, GO:0042246=IEA, GO:0031145=TAS, GO:0005829=TAS, GO:0005737=IDA, GO:0000082=TAS, GO:0000088=TAS, GO:0000086=TAS, GO:0000087=TAS, GO:0071174=IMP, GO:0060623=IEA, GO:0051987=IMP, GO:0042493=IEA, GO:0051437=TAS, GO:0071456=IEA, GO:0048565=IEA, GO:0051439=TAS, GO:0009612=IEA, GO:0071407=IEA, GO:0033129=IEA, GO:0006461=IEA, GO:0016020=IEA, GO:0000942=IDA, GO:0010629=IEA, GO:0001933=IEA, GO:0006468=IEA} G1/S transition of mitotic cell cycle, G2/M transition of mitotic cell cycle, M phase of mitotic cell cycle, anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process, cell cycle, cell cycle checkpoint, cell division, cellular response to fatty acid, cellular response to hypoxia, cellular response to iron(III) ion, cellular response to organic cyclic compound, digestive tract development, in utero embryonic development, mitotic cell cycle, mitotic metaphase plate congression, mitotic nuclear envelope disassembly, mitotic prometaphase, mitotic prophase, mitotic spindle checkpoint, mitotic spindle stabilization, negative regulation of gene expression, negative regulation of protein phosphorylation, oocyte maturation, positive regulation of attachment of spindle microtubules to kinetochore, positive regulation of cardiac muscle cell proliferation, positive regulation of histone phosphorylation, positive regulation of mRNA 3'-end processing, positive regulation of mitotic cell cycle, positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle, protein complex assembly, protein phosphorylation, regulation of chromosome condensation, regulation of cyclin-dependent protein serine/threonine kinase activity, regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle, response to DDT, response to drug, response to mechanical stimulus, spermatogenesis, tissue regeneration, ventricular cardiac muscle cell development centrosome, condensed nuclear chromosome outer kinetochore, cytoplasm, cytosol, membrane, nucleoplasm, nucleus, spindle pole kinase activity, patched binding, protein binding, protein kinase binding Human UniProtKB-KW:KW-0132 CCNB1IP1 IntAct UniProtKB {GO:0005515=PMID:12612082, GO:0016567=GO_REF:0000041, GO:0005694=GO_REF:0000039, GO:0051026=GO_REF:0000019, GO:0035265=GO_REF:0000019, GO:0016874=GO_REF:0000037, GO:0007286=GO_REF:0000019, GO:0001825=GO_REF:0000019, GO:0006915=GO_REF:0000019, GO:0005634=GO_REF:0000039, GO:0046872=GO_REF:0000037, GO:0007132=GO_REF:0000019} Q9NPC3 E3 ubiquitin-protein ligase CCNB1IP1 protein 20130415 {GO:0005515=IPI, GO:0016567=IEA, GO:0005694=IEA, GO:0051026=IEA, GO:0035265=IEA, GO:0016874=IEA, GO:0007286=IEA, GO:0001825=IEA, GO:0006915=IEA, GO:0005634=IEA, GO:0046872=IEA, GO:0007132=IEA} apoptotic process, blastocyst formation, chiasma assembly, meiotic metaphase I, organ growth, protein ubiquitination, spermatid development chromosome, nucleus ligase activity, metal ion binding, protein binding Human UniProtKB:P62972 CCNB2 IntAct UniProtKB {GO:0005515=PMID:23455922, GO:0007077=Reactome:REACT_160255, GO:0000236=Reactome:REACT_682, GO:0005813=PMID:21399614, GO:0019901=GO_REF:0000002, GO:0005634=GO_REF:0000002, GO:0048538=GO_REF:0000019, GO:0000079=GO_REF:0000002, GO:0001701=GO_REF:0000019, GO:0005829=Reactome:REACT_160217, GO:0007049=GO_REF:0000038, GO:0000088=Reactome:REACT_765, GO:0016020=GO_REF:0000019, GO:0000086=Reactome:REACT_2203, GO:0015630=GO_REF:0000054, GO:0000087=Reactome:REACT_910, GO:0000075=Reactome:REACT_1538, GO:0000278=Reactome:REACT_152, GO:0043029=GO_REF:0000019, GO:0040007=GO_REF:0000019, GO:0051301=GO_REF:0000037} O95067 G2/mitotic-specific cyclin-B2 protein 20130415 {GO:0005515=IPI, GO:0007077=TAS, GO:0000236=TAS, GO:0005813=IDA, GO:0019901=IEA, GO:0005634=IEA, GO:0048538=IEA, GO:0000079=IEA, GO:0001701=IEA, GO:0005829=TAS, GO:0007049=IEA, GO:0000088=TAS, GO:0016020=IEA, GO:0000086=TAS, GO:0015630=IDA, GO:0000087=TAS, GO:0000075=TAS, GO:0000278=TAS, GO:0043029=IEA, GO:0040007=IEA, GO:0051301=IEA} G2/M transition of mitotic cell cycle, M phase of mitotic cell cycle, T cell homeostasis, cell cycle, cell cycle checkpoint, cell division, growth, in utero embryonic development, mitotic cell cycle, mitotic nuclear envelope disassembly, mitotic prometaphase, mitotic prophase, regulation of cyclin-dependent protein serine/threonine kinase activity, thymus development centrosome, cytosol, membrane, microtubule cytoskeleton, nucleus protein binding, protein kinase binding Human UniProtKB:P24941 CCNB3 HPA UniProtKB {GO:0005515=PMID:12185076, GO:0007126=GO_REF:0000037, GO:0019901=GO_REF:0000002, GO:0010389=GO_REF:0000002, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0000079=GO_REF:0000002, GO:0051301=GO_REF:0000037} Q8WWL7 G2/mitotic-specific cyclin-B3 protein 20080205 {GO:0005515=IPI, GO:0007126=IEA, GO:0019901=IEA, GO:0010389=IEA, GO:0005730=IDA, GO:0005634=IDA, GO:0000079=IEA, GO:0051301=IEA} cell division, meiosis, regulation of G2/M transition of mitotic cell cycle, regulation of cyclin-dependent protein serine/threonine kinase activity nucleolus, nucleus protein binding, protein kinase binding NOT Human CCNC InterPro UniProtKB {GO:0005515=PMID:19914168, GO:0010467=Reactome:REACT_71, GO:0006355=GO_REF:0000002, GO:0006367=Reactome:REACT_12627, GO:0019901=GO_REF:0000002, GO:0000079=GO_REF:0000002, GO:0006351=Reactome:REACT_121061, GO:0007219=Reactome:REACT_118859, GO:0016592=GO_REF:0000019, GO:0045944=Reactome:REACT_120734, GO:0016591=GO_REF:0000002, GO:0005654=Reactome:REACT_160249, GO:0007179=Reactome:REACT_6844} Q5JV82 Cyclin-C protein 20130413 {GO:0005515=IPI, GO:0010467=TAS, GO:0006355=IEA, GO:0006367=TAS, GO:0019901=IEA, GO:0000079=IEA, GO:0006351=TAS, GO:0007219=TAS, GO:0016592=IEA, GO:0045944=TAS, GO:0016591=IEA, GO:0005654=TAS, GO:0007179=TAS} Notch signaling pathway, gene expression, positive regulation of transcription from RNA polymerase II promoter, regulation of cyclin-dependent protein serine/threonine kinase activity, regulation of transcription, DNA-dependent, transcription initiation from RNA polymerase II promoter, transcription, DNA-dependent, transforming growth factor beta receptor signaling pathway DNA-directed RNA polymerase II, holoenzyme, mediator complex, nucleoplasm protein binding, protein kinase binding Human InterPro:IPR015429 CCND1 BHF-UCL UniProtKB {GO:0005515=PMID:21988832, GO:0043627=GO_REF:0000019, GO:0010165=GO_REF:0000019, GO:0045471=GO_REF:0000019, GO:0031100=GO_REF:0000019, GO:0030178=GO_REF:0000019, GO:0045737=PMID:8114739, GO:0005634=PMID:11793365, GO:0032403=GO_REF:0000019, GO:2000045=GO_REF:0000019, GO:0005829=Reactome:REACT_2142, GO:0030968=GO_REF:0000019, GO:0005622=GO_REF:0000054, GO:0000084=Reactome:REACT_899, GO:0000082=PMID:18483258, GO:0030857=GO_REF:0000019, GO:0010039=GO_REF:0000019, GO:0032026=GO_REF:0000019, GO:0045444=GO_REF:0000019, GO:0033197=GO_REF:0000019, GO:0016538=GO_REF:0000019, GO:0000080=Reactome:REACT_1590, GO:0000320=GO_REF:0000019, GO:0060070=GO_REF:0000019, GO:0051412=GO_REF:0000019, GO:0019901=PMID:8114739, GO:0042493=PMID:18291362, GO:0010243=GO_REF:0000019, GO:0006974=PMID:19412162, GO:0070141=PMID:18483258, GO:0001889=GO_REF:0000019, GO:0051592=GO_REF:0000019, GO:0033598=GO_REF:0000019, GO:0004672=GO_REF:0000019, GO:0016020=GO_REF:0000039, GO:0007595=GO_REF:0000019, GO:0000307=PMID:17420273, GO:0001934=PMID:8114739, GO:0033327=GO_REF:0000019, GO:0005654=Reactome:REACT_111248, GO:0031571=PMID:19412162, GO:0005923=GO_REF:0000019, GO:0000278=Reactome:REACT_152, GO:0019899=PMID:19412162, GO:0033601=GO_REF:0000019, GO:0060749=GO_REF:0000019, GO:0051301=GO_REF:0000037} P24385 G1/S-specific cyclin-D1 protein 20081126 {GO:0005515=IPI, GO:0043627=IEA, GO:0010165=IEA, GO:0045471=IEA, GO:0031100=IEA, GO:0030178=IEA, GO:0045737=IDA, GO:0005634=IDA, GO:0032403=IEA, GO:2000045=IEA, GO:0005829=TAS, GO:0030968=IEA, GO:0005622=IDA, GO:0000084=TAS, GO:0000082=TAS, GO:0030857=IEA, GO:0010039=IEA, GO:0032026=IEA, GO:0045444=IEA, GO:0033197=IEA, GO:0016538=IEA, GO:0000080=TAS, GO:0000320=IEA, GO:0060070=IEA, GO:0051412=IEA, GO:0019901=IPI, GO:0042493=IEP, GO:0010243=IEA, GO:0006974=IDA, GO:0070141=IDA, GO:0001889=IEA, GO:0051592=IEA, GO:0033598=IEA, GO:0004672=IEA, GO:0016020=IEA, GO:0007595=IEA, GO:0000307=IDA, GO:0001934=IDA, GO:0033327=IEA, GO:0005654=TAS, GO:0031571=IDA, GO:0005923=IEA, GO:0000278=TAS, GO:0019899=IPI, GO:0033601=IEA, GO:0060749=IEA, GO:0051301=IEA} G1 phase of mitotic cell cycle, G1/S transition of mitotic cell cycle, Leydig cell differentiation, S phase of mitotic cell cycle, canonical Wnt receptor signaling pathway, cell division, endoplasmic reticulum unfolded protein response, fat cell differentiation, lactation, liver development, mammary gland alveolus development, mammary gland epithelial cell proliferation, mitotic G1 DNA damage checkpoint, mitotic cell cycle, negative regulation of Wnt receptor signaling pathway, negative regulation of epithelial cell differentiation, organ regeneration, positive regulation of cyclin-dependent protein kinase activity, positive regulation of mammary gland epithelial cell proliferation, positive regulation of protein phosphorylation, re-entry into mitotic cell cycle, regulation of G1/S transition of mitotic cell cycle, response to DNA damage stimulus, response to UV-A, response to X-ray, response to calcium ion, response to corticosterone stimulus, response to drug, response to estrogen stimulus, response to ethanol, response to iron ion, response to magnesium ion, response to organic nitrogen, response to vitamin E cyclin-dependent protein kinase holoenzyme complex, cytosol, intracellular, membrane, nucleoplasm, nucleus, tight junction cyclin-dependent protein serine/threonine kinase regulator activity, enzyme binding, protein binding, protein complex binding, protein kinase activity, protein kinase binding Human CCND2 HPA UniProtKB {GO:0031965=PMID:18827403, GO:0007049=GO_REF:0000037, GO:0019901=PMID:8114739, GO:0000307=PMID:8114739, GO:0001934=PMID:8114739, GO:0005730=GO_REF:0000052, GO:0045737=PMID:8114739, GO:0005634=GO_REF:0000052, GO:0000785=PMID:18827403, GO:0005829=PMID:18827403, GO:0051301=GO_REF:0000037} P30279 G1/S-specific cyclin-D2 protein 20120912 {GO:0031965=IDA, GO:0007049=IEA, GO:0019901=IPI, GO:0000307=IDA, GO:0001934=IDA, GO:0005730=IDA, GO:0045737=IDA, GO:0005634=IDA, GO:0000785=IDA, GO:0005829=IDA, GO:0051301=IEA} cell cycle, cell division, positive regulation of cyclin-dependent protein kinase activity, positive regulation of protein phosphorylation chromatin, cyclin-dependent protein kinase holoenzyme complex, cytosol, nuclear membrane, nucleolus, nucleus protein kinase binding NOT Human CCND3 InterPro UniProtKB {GO:0005515=PMID:21988832, GO:0019901=PMID:8114739, GO:0045737=PMID:8114739, GO:0005634=GO_REF:0000002, GO:0007165=GO_REF:0000019, GO:0005737=GO_REF:0000039, GO:0042098=GO_REF:0000019, GO:0016020=GO_REF:0000039, GO:0000307=PMID:8114739, GO:0051726=GO_REF:0000019, GO:0001934=PMID:8114739, GO:0004693=GO_REF:0000019, GO:0051301=GO_REF:0000037} Q5T8J1 G1/S-specific cyclin-D3 protein 20130413 {GO:0005515=IPI, GO:0019901=IPI, GO:0045737=IDA, GO:0005634=IEA, GO:0007165=IEA, GO:0005737=IEA, GO:0042098=IEA, GO:0016020=IEA, GO:0000307=IDA, GO:0051726=IEA, GO:0001934=IDA, GO:0004693=IEA, GO:0051301=IEA} T cell proliferation, cell division, positive regulation of cyclin-dependent protein kinase activity, positive regulation of protein phosphorylation, regulation of cell cycle, signal transduction cyclin-dependent protein kinase holoenzyme complex, cytoplasm, membrane, nucleus cyclin-dependent protein serine/threonine kinase activity, protein binding, protein kinase binding Human InterPro:IPR004367 CCNDBP1 IntAct UniProtKB {GO:0005515=PMID:10915743, GO:0005737=GO_REF:0000039, GO:0007049=GO_REF:0000037, GO:0051726=GO_REF:0000002, GO:0005634=PMID:12437976} O95273 Cyclin-D1-binding protein 1 protein 20130415 {GO:0005515=IPI, GO:0005737=IEA, GO:0007049=IEA, GO:0051726=IEA, GO:0005634=IDA} cell cycle, regulation of cell cycle cytoplasm, nucleus protein binding Human UniProtKB:P15923-1 CCNE1 HPA UniProtKB {GO:0005515=PMID:23455922, GO:0019901=GO_REF:0000019, GO:0003713=PMID:15572661, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0050681=PMID:15572661, GO:0000079=GO_REF:0000002, GO:0005829=Reactome:REACT_1683, GO:0000082=Reactome:REACT_1783, GO:0000083=Reactome:REACT_683, GO:0016301=GO_REF:0000019, GO:0006270=GO_REF:0000019, GO:0000307=GO_REF:0000019, GO:0005654=Reactome:REACT_22145, GO:0006468=PMID:10500095, GO:0016538=GO_REF:0000019, GO:0000278=Reactome:REACT_152, GO:0016055=GO_REF:0000019, GO:0045893=PMID:15572661, GO:0030521=PMID:15572661, GO:0051301=GO_REF:0000037} P24864 G1/S-specific cyclin-E1 protein 20120912 {GO:0005515=IPI, GO:0019901=IEA, GO:0003713=NAS, GO:0005730=IDA, GO:0005634=IDA, GO:0050681=NAS, GO:0000079=IEA, GO:0005829=TAS, GO:0000082=TAS, GO:0000083=TAS, GO:0016301=IEA, GO:0006270=IEA, GO:0000307=IEA, GO:0005654=TAS, GO:0006468=IMP, GO:0016538=IEA, GO:0000278=TAS, GO:0016055=IEA, GO:0045893=NAS, GO:0030521=NAS, GO:0051301=IEA} DNA replication initiation, G1/S transition of mitotic cell cycle, Wnt receptor signaling pathway, androgen receptor signaling pathway, cell division, mitotic cell cycle, positive regulation of transcription, DNA-dependent, protein phosphorylation, regulation of cyclin-dependent protein serine/threonine kinase activity, regulation of transcription involved in G1/S phase of mitotic cell cycle cyclin-dependent protein kinase holoenzyme complex, cytosol, nucleolus, nucleoplasm, nucleus androgen receptor binding, cyclin-dependent protein serine/threonine kinase regulator activity, kinase activity, protein binding, protein kinase binding, transcription coactivator activity NOT Human CCNE2 UniProtKB UniProtKB {GO:0005515=PMID:23455922, GO:0019901=GO_REF:0000002, GO:0005634=GO_REF:0000002, GO:0000079=GO_REF:0000002, GO:0005829=Reactome:REACT_1683, GO:0000082=Reactome:REACT_1783, GO:0007049=GO_REF:0000038, GO:0006270=GO_REF:0000019, GO:0000075=PMID:9858585, GO:0016538=GO_REF:0000019, GO:0005654=Reactome:REACT_9067, GO:0000278=Reactome:REACT_152, GO:0051301=GO_REF:0000038} Q8WUE3 G1/S-specific cyclin-E2 protein 20130413 {GO:0005515=IPI, GO:0019901=IEA, GO:0005634=IEA, GO:0000079=IEA, GO:0005829=TAS, GO:0000082=TAS, GO:0007049=IEA, GO:0006270=IEA, GO:0000075=TAS, GO:0016538=IEA, GO:0005654=TAS, GO:0000278=TAS, GO:0051301=IEA} DNA replication initiation, G1/S transition of mitotic cell cycle, cell cycle, cell cycle checkpoint, cell division, mitotic cell cycle, regulation of cyclin-dependent protein serine/threonine kinase activity cytosol, nucleoplasm, nucleus cyclin-dependent protein serine/threonine kinase regulator activity, protein binding, protein kinase binding Human UniProtKB-KW:KW-0132 CCNF IntAct UniProtKB {GO:0005515=PMID:22632967, GO:0007067=GO_REF:0000037, GO:0016567=PMID:20596027, GO:0005814=PMID:20596027, GO:0010826=PMID:20596027, GO:0005634=PMID:20596027, GO:0001890=GO_REF:0000019, GO:0031146=PMID:20596027, GO:0000320=GO_REF:0000019, GO:0019005=PMID:20596027, GO:0051301=GO_REF:0000037} P41002 Cyclin-F protein 20130415 {GO:0005515=IPI, GO:0007067=IEA, GO:0016567=IDA, GO:0005814=IDA, GO:0010826=IDA, GO:0005634=IDA, GO:0001890=IEA, GO:0031146=IDA, GO:0000320=IEA, GO:0019005=IDA, GO:0051301=IEA} SCF-dependent proteasomal ubiquitin-dependent protein catabolic process, cell division, mitosis, negative regulation of centrosome duplication, placenta development, protein ubiquitination, re-entry into mitotic cell cycle SCF ubiquitin ligase complex, centriole, nucleus protein binding Human UniProtKB:P63208 CCNG1 IntAct UniProtKB {GO:0005515=PMID:21988832, GO:0007095=GO_REF:0000019, GO:0043066=GO_REF:0000019, GO:0048471=GO_REF:0000019, GO:0019904=GO_REF:0000019, GO:0010243=GO_REF:0000019, GO:0005634=GO_REF:0000039, GO:0000079=PMID:8626390, GO:0030425=GO_REF:0000019, GO:0007067=GO_REF:0000037, GO:0006949=GO_REF:0000019, GO:0007420=GO_REF:0000019, GO:0043025=GO_REF:0000019, GO:0016049=GO_REF:0000019, GO:0051301=GO_REF:0000037} P51959 Cyclin-G1 protein 20130415 {GO:0005515=IPI, GO:0007095=IEA, GO:0043066=IEA, GO:0048471=IEA, GO:0019904=IEA, GO:0010243=IEA, GO:0005634=IEA, GO:0000079=TAS, GO:0030425=IEA, GO:0007067=IEA, GO:0006949=IEA, GO:0007420=IEA, GO:0043025=IEA, GO:0016049=IEA, GO:0051301=IEA} brain development, cell division, cell growth, mitosis, mitotic G2 DNA damage checkpoint, negative regulation of apoptotic process, regulation of cyclin-dependent protein serine/threonine kinase activity, response to organic nitrogen, syncytium formation dendrite, neuronal cell body, nucleus, perinuclear region of cytoplasm protein binding, protein domain specific binding Human UniProtKB:Q15025 CCNG2 PINC UniProtKB {GO:0005737=GO_REF:0000039, GO:0007067=GO_REF:0000037, GO:0051726=GO_REF:0000019, GO:0000075=PMID:8626390, GO:0051301=GO_REF:0000037} Q16589 Cyclin-G2 protein 20030904 {GO:0005737=IEA, GO:0007067=IEA, GO:0051726=IEA, GO:0000075=TAS, GO:0051301=IEA} cell cycle checkpoint, cell division, mitosis, regulation of cell cycle cytoplasm Human CCNH GOC UniProtKB {GO:0005515=PMID:21988832, GO:0022415=Reactome:REACT_6361, GO:0010467=Reactome:REACT_71, GO:0006368=Reactome:REACT_2089, GO:0006367=Reactome:REACT_1851, GO:0006366=Reactome:REACT_1366, GO:0006363=Reactome:REACT_1074, GO:0006362=Reactome:REACT_2204, GO:0006361=Reactome:REACT_1974, GO:0006360=Reactome:REACT_1309, GO:0005634=PMID:7936635, GO:0000079=GO_REF:0000002, GO:0070985=GO_REF:0000002, GO:0000084=Reactome:REACT_899, GO:0000082=Reactome:REACT_1783, GO:0016301=GO_REF:0000019, GO:0045944=PMID:8692841, GO:0000086=Reactome:REACT_2203, GO:0016032=Reactome:REACT_6256, GO:0016538=GO_REF:0000002, GO:0000080=Reactome:REACT_1590, GO:0008094=PMID:9852112, GO:0019907=PMID:8692842, GO:0006355=GO_REF:0000002, GO:0019901=GO_REF:0000002, GO:0006370=Reactome:REACT_1470, GO:0008353=PMID:9852112, GO:0006351=GO_REF:0000002, GO:0050434=Reactome:REACT_6162, GO:0004672=PMID:9852112, GO:0006281=Reactome:REACT_216, GO:0006283=Reactome:REACT_1628, GO:0006468=PMID:9852112, GO:0005654=Reactome:REACT_9070, GO:0006289=Reactome:REACT_1826, GO:0000278=Reactome:REACT_152, GO:0000718=Reactome:REACT_311, GO:0005675=PMID:9852112} P51946 Cyclin-H protein 20130413 {GO:0005515=IPI, GO:0022415=TAS, GO:0010467=TAS, GO:0006368=TAS, GO:0006367=TAS, GO:0006366=TAS, GO:0006363=TAS, GO:0006362=TAS, GO:0006361=TAS, GO:0006360=TAS, GO:0005634=TAS, GO:0000079=IEA, GO:0070985=IEA, GO:0000084=TAS, GO:0000082=TAS, GO:0016301=IEA, GO:0045944=IDA, GO:0000086=TAS, GO:0016032=TAS, GO:0016538=IEA, GO:0000080=TAS, GO:0008094=IDA, GO:0019907=IDA, GO:0006355=IEA, GO:0019901=IEA, GO:0006370=TAS, GO:0008353=IDA, GO:0006351=IEA, GO:0050434=TAS, GO:0004672=IDA, GO:0006281=TAS, GO:0006283=TAS, GO:0006468=IDA, GO:0005654=TAS, GO:0006289=TAS, GO:0000278=TAS, GO:0000718=TAS, GO:0005675=IDA} 7-methylguanosine mRNA capping, DNA repair, G1 phase of mitotic cell cycle, G1/S transition of mitotic cell cycle, G2/M transition of mitotic cell cycle, S phase of mitotic cell cycle, gene expression, mitotic cell cycle, nucleotide-excision repair, nucleotide-excision repair, DNA damage removal, positive regulation of transcription from RNA polymerase II promoter, positive regulation of viral transcription, protein phosphorylation, regulation of cyclin-dependent protein serine/threonine kinase activity, regulation of transcription, DNA-dependent, termination of RNA polymerase I transcription, transcription elongation from RNA polymerase I promoter, transcription elongation from RNA polymerase II promoter, transcription from RNA polymerase I promoter, transcription from RNA polymerase II promoter, transcription initiation from RNA polymerase I promoter, transcription initiation from RNA polymerase II promoter, transcription, DNA-dependent, transcription-coupled nucleotide-excision repair, viral reproduction, viral reproductive process TFIIK complex, cyclin-dependent protein kinase activating kinase holoenzyme complex, holo TFIIH complex, nucleoplasm, nucleus DNA-dependent ATPase activity, RNA polymerase II carboxy-terminal domain kinase activity, cyclin-dependent protein serine/threonine kinase regulator activity, kinase activity, protein binding, protein kinase activity, protein kinase binding Human CCNI UniProtKB UniProtKB {GO:0007283=PMID:9705831} Q14094 Cyclin-I protein 20021113 {GO:0007283=NAS} spermatogenesis Human CCNJ InterPro UniProtKB {GO:0005634=GO_REF:0000002} Q5T5M9 Cyclin-J protein 20130413 {GO:0005634=IEA} nucleus Human InterPro:IPR004367 CCNK IntAct UniProtKB {GO:0005515=PMID:16713569, GO:0071157=PMID:9632813, GO:0006355=GO_REF:0000037, GO:0019901=PMID:22012619, GO:0006366=PMID:9632813, GO:0000079=GO_REF:0000002, GO:0008353=PMID:9632813, GO:0006974=PMID:22012619, GO:0002945=PMID:22012619, GO:0007067=GO_REF:0000037, GO:0002944=PMID:22012619, GO:0051301=GO_REF:0000037, GO:0004693=PMID:9632813} O75909 Cyclin-K protein 20130415 {GO:0005515=IPI, GO:0071157=IGI, GO:0006355=IEA, GO:0019901=IPI, GO:0006366=TAS, GO:0000079=IEA, GO:0008353=IDA, GO:0006974=IMP, GO:0002945=IPI, GO:0007067=IEA, GO:0002944=IPI, GO:0051301=IEA, GO:0004693=IDA} cell division, mitosis, negative regulation of cell cycle arrest, regulation of cyclin-dependent protein serine/threonine kinase activity, regulation of transcription, DNA-dependent, response to DNA damage stimulus, transcription from RNA polymerase II promoter cyclin K-CDK12 complex, cyclin K-CDK13 complex RNA polymerase II carboxy-terminal domain kinase activity, cyclin-dependent protein serine/threonine kinase activity, protein binding, protein kinase binding Human UniProtKB:P54253 CCNL1 MGI UniProtKB {GO:0006396=GO_REF:0000002, GO:0006355=GO_REF:0000037, GO:0016607=GO_REF:0000039, GO:0019901=GO_REF:0000002, GO:0005634=PMID:17494991, GO:0000079=GO_REF:0000002, GO:0006351=GO_REF:0000037} Q9UK58 Cyclin-L1 protein 20130220 {GO:0006396=IEA, GO:0006355=IEA, GO:0016607=IEA, GO:0019901=IEA, GO:0005634=IDA, GO:0000079=IEA, GO:0006351=IEA} RNA processing, regulation of cyclin-dependent protein serine/threonine kinase activity, regulation of transcription, DNA-dependent, transcription, DNA-dependent nuclear speck, nucleus protein kinase binding Human CCNL2 MGI UniProtKB {GO:0006396=GO_REF:0000002, GO:0006355=GO_REF:0000037, GO:0016607=GO_REF:0000039, GO:0019901=GO_REF:0000002, GO:0005634=PMID:17494991, GO:0000079=GO_REF:0000002, GO:0006351=GO_REF:0000037} Q96S94 Cyclin-L2 protein 20120321 {GO:0006396=IEA, GO:0006355=IEA, GO:0016607=IEA, GO:0019901=IEA, GO:0005634=IDA, GO:0000079=IEA, GO:0006351=IEA} RNA processing, regulation of cyclin-dependent protein serine/threonine kinase activity, regulation of transcription, DNA-dependent, transcription, DNA-dependent nuclear speck, nucleus protein kinase binding Human CCNO Reactome UniProtKB {GO:0004844=PMID:12161446, GO:0007049=PMID:8419333, GO:0006281=Reactome:REACT_216, GO:0019901=GO_REF:0000002, GO:0006284=Reactome:REACT_1104, GO:0045008=Reactome:REACT_2156, GO:0006285=Reactome:REACT_804, GO:0005654=Reactome:REACT_1630, GO:0000079=GO_REF:0000002, GO:0051301=PMID:8419333} P22674 Cyclin-O protein 20130213 {GO:0004844=IDA, GO:0007049=IDA, GO:0006281=TAS, GO:0019901=IEA, GO:0006284=TAS, GO:0045008=TAS, GO:0006285=TAS, GO:0005654=TAS, GO:0000079=IEA, GO:0051301=IDA} DNA repair, base-excision repair, base-excision repair, AP site formation, cell cycle, cell division, depyrimidination, regulation of cyclin-dependent protein serine/threonine kinase activity nucleoplasm protein kinase binding, uracil DNA N-glycosylase activity Human CCNT1 HPA UniProtKB {GO:0005515=PMID:22190034, GO:0010467=Reactome:REACT_71, GO:0022415=Reactome:REACT_6361, GO:0006368=Reactome:REACT_1845, GO:0006367=Reactome:REACT_12627, GO:0044212=GO_REF:0000019, GO:0006366=Reactome:REACT_1366, GO:0005634=GO_REF:0000052, GO:0000079=GO_REF:0000002, GO:0045944=Reactome:REACT_120734, GO:0016032=Reactome:REACT_6256, GO:0007179=Reactome:REACT_6844, GO:0008024=PMID:15905409, GO:0019901=GO_REF:0000002, GO:0005730=GO_REF:0000052, GO:0003677=PMID:16109376, GO:0006351=Reactome:REACT_121061, GO:0050434=Reactome:REACT_6162, GO:0007049=GO_REF:0000037, GO:0003682=GO_REF:0000019, GO:0019048=GO_REF:0000037, GO:0017069=GO_REF:0000019, GO:0006468=PMID:16109376, GO:0005654=Reactome:REACT_121336, GO:0051301=GO_REF:0000037} O60563 Cyclin-T1 protein 20080818 {GO:0005515=IPI, GO:0010467=TAS, GO:0022415=TAS, GO:0006368=TAS, GO:0006367=TAS, GO:0044212=IEA, GO:0006366=TAS, GO:0005634=IDA, GO:0000079=IEA, GO:0045944=TAS, GO:0016032=TAS, GO:0007179=TAS, GO:0008024=IDA, GO:0019901=IEA, GO:0005730=IDA, GO:0003677=IDA, GO:0006351=TAS, GO:0050434=TAS, GO:0007049=IEA, GO:0003682=IEA, GO:0019048=IEA, GO:0017069=IEA, GO:0006468=IPI, GO:0005654=TAS, GO:0051301=IEA} cell cycle, cell division, gene expression, positive regulation of transcription from RNA polymerase II promoter, positive regulation of viral transcription, protein phosphorylation, regulation of cyclin-dependent protein serine/threonine kinase activity, transcription elongation from RNA polymerase II promoter, transcription from RNA polymerase II promoter, transcription initiation from RNA polymerase II promoter, transcription, DNA-dependent, transforming growth factor beta receptor signaling pathway, viral reproduction, viral reproductive process, virus-host interaction nucleolus, nucleoplasm, nucleus, positive transcription elongation factor complex b DNA binding, chromatin binding, protein binding, protein kinase binding, snRNA binding, transcription regulatory region DNA binding NOT Human CCNT2 Reactome UniProtKB {GO:0022415=Reactome:REACT_6361, GO:0010467=Reactome:REACT_71, GO:0006355=GO_REF:0000002, GO:0006368=Reactome:REACT_1845, GO:0006367=Reactome:REACT_12627, GO:0019901=GO_REF:0000002, GO:0006366=Reactome:REACT_1366, GO:0005634=PMID:16109376, GO:0000079=GO_REF:0000002, GO:0006351=Reactome:REACT_121061, GO:0007049=GO_REF:0000037, GO:0045944=Reactome:REACT_120734, GO:0019048=GO_REF:0000037, GO:0016032=Reactome:REACT_6256, GO:0005654=Reactome:REACT_121336, GO:0007179=Reactome:REACT_6844, GO:0051301=GO_REF:0000037} O60583 Cyclin-T2 protein 20130301 {GO:0022415=TAS, GO:0010467=TAS, GO:0006355=IEA, GO:0006368=TAS, GO:0006367=TAS, GO:0019901=IEA, GO:0006366=TAS, GO:0005634=IDA, GO:0000079=IEA, GO:0006351=TAS, GO:0007049=IEA, GO:0045944=TAS, GO:0019048=IEA, GO:0016032=TAS, GO:0005654=TAS, GO:0007179=TAS, GO:0051301=IEA} cell cycle, cell division, gene expression, positive regulation of transcription from RNA polymerase II promoter, regulation of cyclin-dependent protein serine/threonine kinase activity, regulation of transcription, DNA-dependent, transcription elongation from RNA polymerase II promoter, transcription from RNA polymerase II promoter, transcription initiation from RNA polymerase II promoter, transcription, DNA-dependent, transforming growth factor beta receptor signaling pathway, viral reproduction, viral reproductive process, virus-host interaction nucleoplasm, nucleus protein kinase binding Human CCNY LIFEdb UniProtKB {GO:0005515=PMID:19524571, GO:0005886=PMID:19524571, GO:0019901=GO_REF:0000002, GO:0000086=PMID:20059949, GO:0000308=PMID:20059949, GO:0045737=PMID:20059949, GO:0005634=GO_REF:0000054, GO:0016538=PMID:20059949, GO:0000079=GO_REF:0000002, GO:0016055=GO_REF:0000037, GO:0060828=PMID:20059949, GO:0051301=GO_REF:0000037} Q8ND76 Cyclin-Y protein 20100607 {GO:0005515=IPI, GO:0005886=IDA, GO:0019901=IEA, GO:0000086=IDA, GO:0000308=IDA, GO:0045737=IDA, GO:0005634=IDA, GO:0016538=IDA, GO:0000079=IEA, GO:0016055=IEA, GO:0060828=IDA, GO:0051301=IEA} G2/M transition of mitotic cell cycle, Wnt receptor signaling pathway, cell division, positive regulation of cyclin-dependent protein kinase activity, regulation of canonical Wnt receptor signaling pathway, regulation of cyclin-dependent protein serine/threonine kinase activity cytoplasmic cyclin-dependent protein kinase holoenzyme complex, nucleus, plasma membrane cyclin-dependent protein serine/threonine kinase regulator activity, protein binding, protein kinase binding Human CCNYL1 InterPro UniProtKB {GO:0019901=GO_REF:0000002, GO:0000079=GO_REF:0000002} Q8N7R7 Cyclin-Y-like protein 1 protein 20130413 {GO:0019901=IEA, GO:0000079=IEA} regulation of cyclin-dependent protein serine/threonine kinase activity protein kinase binding Human InterPro:IPR012399 CCP110 IntAct UniProtKB {GO:0005515=PMID:21620453, GO:0051298=PMID:20596027, GO:0005813=PMID:21399614, GO:0032465=PMID:16760425, GO:0007099=PMID:17681131, GO:0005814=PMID:20596027, GO:0000086=Reactome:REACT_2203, GO:0030030=GO_REF:0000037, GO:0000278=Reactome:REACT_152, GO:0005829=Reactome:REACT_15470} O43303 Centriolar coiled-coil protein of 110 kDa protein 20130415 {GO:0005515=IPI, GO:0051298=IDA, GO:0005813=IDA, GO:0032465=IMP, GO:0007099=IMP, GO:0005814=IDA, GO:0000086=TAS, GO:0030030=IEA, GO:0000278=TAS, GO:0005829=TAS} G2/M transition of mitotic cell cycle, cell projection organization, centriole replication, centrosome duplication, mitotic cell cycle, regulation of cytokinesis centriole, centrosome, cytosol protein binding Human UniProtKB:Q8IW35 CCPG1 UniProtKB UniProtKB {GO:0007049=GO_REF:0000037, GO:0016020=GO_REF:0000019, GO:0045944=GO_REF:0000019, GO:2001106=GO_REF:0000019, GO:0016021=GO_REF:0000037} Q9ULG6 Cell cycle progression protein 1 protein 20130413 {GO:0007049=IEA, GO:0016020=IEA, GO:0045944=IEA, GO:2001106=IEA, GO:0016021=IEA} cell cycle, positive regulation of transcription from RNA polymerase II promoter, regulation of Rho guanyl-nucleotide exchange factor activity integral to membrane, membrane Human UniProtKB-KW:KW-0812 CCR1 BHF-UCL UniProtKB {GO:0071791=PMID:10660125, GO:0005515=PMID:15001559, GO:0005886=Reactome:REACT_22289, GO:0051928=PMID:15764707, GO:0019221=PMID:15474493, GO:0007267=PMID:10734056, GO:0006887=PMID:10734056, GO:0007204=PMID:10734056, GO:0019957=PMID:8699119, GO:0006955=PMID:10734056, GO:0006954=GO_REF:0000002, GO:0006935=PMID:15474493, GO:0004950=PMID:10660125, GO:0006816=PMID:10734056, GO:0007155=PMID:10910894, GO:0070098=PMID:21403648, GO:0002407=PMID:16621978, GO:0009611=PMID:7505609, GO:0006874=PMID:10734056, GO:0045672=PMID:21403648, GO:0004435=PMID:10734056, GO:0005887=PMID:7505609, GO:0007187=PMID:7505609, GO:0035717=PMID:10660125, GO:0016493=PMID:10734056, GO:0090026=PMID:18587271, GO:0007166=PMID:10770925} P32246 C-C chemokine receptor type 1 protein 20110322 {GO:0071791=IPI, GO:0005515=IPI, GO:0005886=TAS, GO:0051928=IDA, GO:0019221=NAS, GO:0007267=IDA, GO:0006887=IDA, GO:0007204=IDA, GO:0019957=IPI, GO:0006955=IDA, GO:0006954=IEA, GO:0006935=NAS, GO:0004950=IDA, GO:0006816=IDA, GO:0007155=TAS, GO:0070098=IDA, GO:0002407=TAS, GO:0009611=TAS, GO:0006874=IDA, GO:0045672=IMP, GO:0004435=IDA, GO:0005887=TAS, GO:0007187=TAS, GO:0035717=IPI, GO:0016493=IDA, GO:0090026=IDA, GO:0007166=TAS} G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger, calcium ion transport, cell adhesion, cell surface receptor signaling pathway, cell-cell signaling, cellular calcium ion homeostasis, chemokine-mediated signaling pathway, chemotaxis, cytokine-mediated signaling pathway, dendritic cell chemotaxis, elevation of cytosolic calcium ion concentration, exocytosis, immune response, inflammatory response, positive regulation of calcium ion transport, positive regulation of monocyte chemotaxis, positive regulation of osteoclast differentiation, response to wounding integral to plasma membrane, plasma membrane C-C chemokine binding, C-C chemokine receptor activity, chemokine (C-C motif) ligand 5 binding, chemokine (C-C motif) ligand 7 binding, chemokine receptor activity, phosphatidylinositol phospholipase C activity, protein binding Human CCR10 Reactome UniProtKB {GO:0006955=GO_REF:0000002, GO:0005886=Reactome:REACT_22289, GO:0007186=PMID:7851889, GO:0006935=GO_REF:0000019, GO:0005887=PMID:7851889, GO:0004930=PMID:7851889, GO:0016493=GO_REF:0000019, GO:0016021=GO_REF:0000002, GO:0007204=GO_REF:0000019, GO:0019957=GO_REF:0000002} P46092 C-C chemokine receptor type 10 protein 20100217 {GO:0006955=IEA, GO:0005886=TAS, GO:0007186=TAS, GO:0006935=IEA, GO:0005887=TAS, GO:0004930=TAS, GO:0016493=IEA, GO:0016021=IEA, GO:0007204=IEA, GO:0019957=IEA} G-protein coupled receptor signaling pathway, chemotaxis, elevation of cytosolic calcium ion concentration, immune response integral to membrane, integral to plasma membrane, plasma membrane C-C chemokine binding, C-C chemokine receptor activity, G-protein coupled receptor activity Human CCR2 BHF-UCL UniProtKB {GO:0043310=GO_REF:0000024, GO:0019221=PMID:15995708, GO:2000451=GO_REF:0000024, GO:0090265=GO_REF:0000024, GO:0019957=GO_REF:0000002, GO:0042803=GO_REF:0000024, GO:0006935=PMID:10623817, GO:0031727=PMID:15995708, GO:0004950=PMID:10623817, GO:0043025=GO_REF:0000024, GO:0035705=GO_REF:0000024, GO:0046641=GO_REF:0000024, GO:0032729=GO_REF:0000024, GO:0070098=GO_REF:0000024, GO:0042535=GO_REF:0000024, GO:2000464=PMID:12271471, GO:0005887=PMID:8146186, GO:0045087=Reactome:REACT_6802, GO:0050870=GO_REF:0000024, GO:0016493=GO_REF:0000002, GO:0090026=GO_REF:0000024, GO:2000473=GO_REF:0000024, GO:0048471=GO_REF:0000024, GO:0005886=Reactome:REACT_115754, GO:2000439=GO_REF:0000024, GO:0007194=GO_REF:0000002, GO:0007204=GO_REF:0000002, GO:0030425=GO_REF:0000024, GO:0005829=GO_REF:0000024, GO:0006955=PMID:10751368, GO:0005737=PMID:15995708, GO:0006954=GO_REF:0000002, GO:0002829=GO_REF:0000024, GO:0002827=GO_REF:0000024, GO:0043204=GO_REF:0000024, GO:0019725=GO_REF:0000024, GO:0032743=GO_REF:0000024, GO:0010820=GO_REF:0000024, GO:0002407=PMID:16621978, GO:0009611=PMID:8146186, GO:0006874=GO_REF:0000024, GO:0007259=PMID:9670957, GO:0010574=GO_REF:0000024, GO:0006968=PMID:10201901, GO:0001974=GO_REF:0000024, GO:0019048=GO_REF:0000037, GO:0016525=GO_REF:0000024, GO:0050729=GO_REF:0000024, GO:0016021=PMID:8530354} P41597 C-C chemokine receptor type 2 protein 20110225 {GO:0043310=ISS, GO:0019221=IDA, GO:2000451=ISS, GO:0090265=ISS, GO:0019957=IEA, GO:0042803=ISS, GO:0006935=TAS, GO:0031727=IDA, GO:0004950=TAS, GO:0043025=ISS, GO:0035705=ISS, GO:0046641=ISS, GO:0032729=ISS, GO:0070098=ISS, GO:0042535=ISS, GO:2000464=IDA, GO:0005887=TAS, GO:0045087=TAS, GO:0050870=ISS, GO:0016493=IEA, GO:0090026=ISS, GO:2000473=ISS, GO:0048471=ISS, GO:0005886=TAS, GO:2000439=ISS, GO:0007194=IEA, GO:0007204=IEA, GO:0030425=ISS, GO:0005829=ISS, GO:0006955=TAS, GO:0005737=IDA, GO:0006954=IEA, GO:0002829=ISS, GO:0002827=ISS, GO:0043204=ISS, GO:0019725=ISS, GO:0032743=ISS, GO:0010820=ISS, GO:0002407=TAS, GO:0009611=TAS, GO:0006874=ISS, GO:0007259=TAS, GO:0010574=ISS, GO:0006968=TAS, GO:0001974=ISS, GO:0019048=IEA, GO:0016525=ISS, GO:0050729=ISS, GO:0016021=TAS} JAK-STAT cascade, T-helper 17 cell chemotaxis, blood vessel remodeling, cellular calcium ion homeostasis, cellular defense response, cellular homeostasis, chemokine-mediated signaling pathway, chemotaxis, cytokine-mediated signaling pathway, dendritic cell chemotaxis, elevation of cytosolic calcium ion concentration, immune response, inflammatory response, innate immune response, negative regulation of adenylate cyclase activity, negative regulation of angiogenesis, negative regulation of eosinophil degranulation, negative regulation of type 2 immune response, positive regulation of CD8-positive, alpha-beta T cell extravasation, positive regulation of T cell activation, positive regulation of T cell chemotaxis, positive regulation of T-helper 1 type immune response, positive regulation of alpha-beta T cell proliferation, positive regulation of astrocyte chemotaxis, positive regulation of hematopoietic stem cell migration, positive regulation of immune complex clearance by monocytes and macrophages, positive regulation of inflammatory response, positive regulation of interferon-gamma production, positive regulation of interleukin-2 production, positive regulation of monocyte chemotaxis, positive regulation of monocyte extravasation, positive regulation of tumor necrosis factor biosynthetic process, regulation of vascular endothelial growth factor production, response to wounding, virus-host interaction cytoplasm, cytosol, dendrite, integral to membrane, integral to plasma membrane, neuronal cell body, perikaryon, perinuclear region of cytoplasm, plasma membrane C-C chemokine binding, C-C chemokine receptor activity, CCR2 chemokine receptor binding, chemokine receptor activity, protein homodimerization activity Human UniProtKB:O55193 CCR3 ENSEMBL UniProtKB {GO:0070098=PMID:10415069, GO:0005886=GO_REF:0000019, GO:0007204=GO_REF:0000002, GO:0005615=GO_REF:0000019, GO:0019957=GO_REF:0000002, GO:0045766=GO_REF:0000019, GO:0006968=PMID:10713092, GO:0006954=GO_REF:0000002, GO:0006935=GO_REF:0000002, GO:0001938=GO_REF:0000019, GO:0005887=PMID:9302298, GO:0019048=GO_REF:0000037, GO:0002551=GO_REF:0000019, GO:0004950=PMID:10415069, GO:0048245=GO_REF:0000019, GO:0007188=PMID:10201960, GO:0016493=GO_REF:0000019, GO:0016021=GO_REF:0000038, GO:0007155=PMID:10201960, GO:0070371=GO_REF:0000019, GO:0005768=GO_REF:0000019, GO:0035476=GO_REF:0000019} Q8TDP5 CC chemokine receptor 3 protein 20130413 {GO:0070098=TAS, GO:0005886=IEA, GO:0007204=IEA, GO:0005615=IEA, GO:0019957=IEA, GO:0045766=IEA, GO:0006968=TAS, GO:0006954=IEA, GO:0006935=IEA, GO:0001938=IEA, GO:0005887=TAS, GO:0019048=IEA, GO:0002551=IEA, GO:0004950=TAS, GO:0048245=IEA, GO:0007188=TAS, GO:0016493=IEA, GO:0016021=IEA, GO:0007155=TAS, GO:0070371=IEA, GO:0005768=IEA, GO:0035476=IEA} ERK1 and ERK2 cascade, adenylate cyclase-modulating G-protein coupled receptor signaling pathway, angioblast cell migration, cell adhesion, cellular defense response, chemokine-mediated signaling pathway, chemotaxis, elevation of cytosolic calcium ion concentration, eosinophil chemotaxis, inflammatory response, mast cell chemotaxis, positive regulation of angiogenesis, positive regulation of endothelial cell proliferation, virus-host interaction endosome, extracellular space, integral to membrane, integral to plasma membrane, plasma membrane C-C chemokine binding, C-C chemokine receptor activity, chemokine receptor activity Human Ensembl:ENSRNOP00000008809 CCR4 GOC UniProtKB {GO:0070098=PMID:7642634, GO:0005886=Reactome:REACT_22289, GO:0002507=GO_REF:0000019, GO:0007204=GO_REF:0000002, GO:0019957=GO_REF:0000002, GO:0006955=GO_REF:0000002, GO:0006954=GO_REF:0000019, GO:0006935=GO_REF:0000019, GO:0005887=PMID:7642634, GO:0004950=PMID:7642634, GO:0016493=GO_REF:0000019, GO:0001764=GO_REF:0000019, GO:0009897=GO_REF:0000019} P51679 C-C chemokine receptor type 4 protein 20130413 {GO:0070098=TAS, GO:0005886=TAS, GO:0002507=IEA, GO:0007204=IEA, GO:0019957=IEA, GO:0006955=IEA, GO:0006954=IEA, GO:0006935=IEA, GO:0005887=TAS, GO:0004950=TAS, GO:0016493=IEA, GO:0001764=IEA, GO:0009897=IEA} chemokine-mediated signaling pathway, chemotaxis, elevation of cytosolic calcium ion concentration, immune response, inflammatory response, neuron migration, tolerance induction external side of plasma membrane, integral to plasma membrane, plasma membrane C-C chemokine binding, C-C chemokine receptor activity, chemokine receptor activity Human CCR5 GOC UniProtKB {GO:0071791=PMID:8699119, GO:0005515=PMID:15001559, GO:0022415=Reactome:REACT_6266, GO:0019722=PMID:19523456, GO:0005886=Reactome:REACT_22289, GO:0030260=Reactome:REACT_6903, GO:0030818=GO_REF:0000002, GO:0007267=PMID:10679098, GO:0007204=PMID:10201901, GO:0019957=PMID:8699119, GO:0006955=GO_REF:0000002, GO:0005737=PMID:10415069, GO:0006954=GO_REF:0000002, GO:0006935=PMID:10741397, GO:0000165=PMID:12032188, GO:0004950=PMID:10201901, GO:0016032=Reactome:REACT_6256, GO:0006816=PMID:8699119, GO:0070098=PMID:10201901, GO:0009986=PMID:10521508, GO:0023052=PMID:12032188, GO:0002407=PMID:16621978, GO:0003779=PMID:12421915, GO:0014808=PMID:19523456, GO:0015026=PMID:10469138, GO:0006968=PMID:10201901, GO:0007186=PMID:19523456, GO:0004435=PMID:8663314, GO:0005887=PMID:10393923, GO:0019048=GO_REF:0000037, GO:0070723=PMID:19523456, GO:0016493=PMID:11278962, GO:0009897=PMID:11278962, GO:0007166=PMID:8639485, GO:0005768=PMID:10679098} P51681 C-C chemokine receptor type 5 protein 20130413 {GO:0071791=IPI, GO:0005515=IPI, GO:0022415=TAS, GO:0019722=IDA, GO:0005886=TAS, GO:0030260=TAS, GO:0030818=IEA, GO:0007267=IDA, GO:0007204=TAS, GO:0019957=IPI, GO:0006955=IEA, GO:0005737=TAS, GO:0006954=IEA, GO:0006935=TAS, GO:0000165=IEP, GO:0004950=TAS, GO:0016032=TAS, GO:0006816=IDA, GO:0070098=TAS, GO:0009986=IDA, GO:0023052=IEP, GO:0002407=TAS, GO:0003779=IDA, GO:0014808=IDA, GO:0015026=TAS, GO:0006968=TAS, GO:0007186=IMP, GO:0004435=TAS, GO:0005887=TAS, GO:0019048=IEA, GO:0070723=IMP, GO:0016493=IDA, GO:0009897=IDA, GO:0007166=TAS, GO:0005768=IDA} G-protein coupled receptor signaling pathway, MAPK cascade, calcium ion transport, calcium-mediated signaling, cell surface receptor signaling pathway, cell-cell signaling, cellular defense response, chemokine-mediated signaling pathway, chemotaxis, dendritic cell chemotaxis, elevation of cytosolic calcium ion concentration, entry into host cell, immune response, inflammatory response, negative regulation of cAMP biosynthetic process, release of sequestered calcium ion into cytosol by sarcoplasmic reticulum, response to cholesterol, signaling, viral reproduction, viral reproductive process, virus-host interaction cell surface, cytoplasm, endosome, external side of plasma membrane, integral to plasma membrane, plasma membrane C-C chemokine binding, C-C chemokine receptor activity, actin binding, chemokine (C-C motif) ligand 5 binding, chemokine receptor activity, coreceptor activity, phosphatidylinositol phospholipase C activity, protein binding Human CCR6 GOC UniProtKB {GO:0070098=PMID:11001880, GO:0005886=Reactome:REACT_115591, GO:0030818=GO_REF:0000002, GO:0002407=PMID:16621978, GO:0006928=PMID:9186513, GO:0007204=GO_REF:0000002, GO:0019957=GO_REF:0000002, GO:0007165=PMID:9186513, GO:0006955=PMID:9223454, GO:0006968=PMID:10521347, GO:0006935=PMID:11001880, GO:0005887=PMID:9186513, GO:0045087=Reactome:REACT_6802, GO:0006959=PMID:11001880, GO:0004950=PMID:11001880, GO:0016493=GO_REF:0000002, GO:0004872=PMID:9186513} P51684 C-C chemokine receptor type 6 protein 20130413 {GO:0070098=TAS, GO:0005886=TAS, GO:0030818=IEA, GO:0002407=TAS, GO:0006928=TAS, GO:0007204=IEA, GO:0019957=IEA, GO:0007165=TAS, GO:0006955=TAS, GO:0006968=TAS, GO:0006935=TAS, GO:0005887=TAS, GO:0045087=TAS, GO:0006959=TAS, GO:0004950=TAS, GO:0016493=IEA, GO:0004872=TAS} cellular component movement, cellular defense response, chemokine-mediated signaling pathway, chemotaxis, dendritic cell chemotaxis, elevation of cytosolic calcium ion concentration, humoral immune response, immune response, innate immune response, negative regulation of cAMP biosynthetic process, signal transduction integral to plasma membrane, plasma membrane C-C chemokine binding, C-C chemokine receptor activity, chemokine receptor activity, receptor activity Human CCR7 GOC UniProtKB {GO:0002885=GO_REF:0000024, GO:0071731=PMID:16249377, GO:0046330=PMID:15778365, GO:0051491=PMID:15569314, GO:2000510=GO_REF:0000024, GO:2000147=PMID:15778365, GO:0031529=PMID:15569314, GO:0005622=PMID:21051556, GO:0032649=GO_REF:0000024, GO:0006935=GO_REF:0000019, GO:0043552=PMID:15778365, GO:0030838=PMID:11242036, GO:0034695=PMID:14592837, GO:0045860=PMID:14592837, GO:0032496=GO_REF:0000019, GO:0031274=PMID:11242036, GO:0070374=PMID:12729902, GO:0043123=PMID:15059845, GO:2000525=GO_REF:0000024, GO:2000526=GO_REF:0000024, GO:0051209=PMID:14592837, GO:0004930=PMID:16621978, GO:0032862=PMID:15778365, GO:2000522=GO_REF:0000024, GO:0045785=PMID:15569314, GO:0007186=PMID:16621978, GO:0090023=PMID:21051556, GO:0016493=GO_REF:0000024, GO:0050706=GO_REF:0000024, GO:0035758=PMID:9507024, GO:0009897=GO_REF:0000019, GO:0001954=PMID:15569314, GO:0035757=PMID:9507024, GO:0051897=PMID:15778365, GO:0005886=PMID:21051556, GO:0032735=GO_REF:0000024, GO:0097022=PMID:18379575, GO:0097029=GO_REF:0000024, GO:0007204=PMID:9153236, GO:0006955=GO_REF:0000019, GO:0006954=PMID:14592837, GO:0072610=GO_REF:0000024, GO:0038115=PMID:9507024, GO:0038116=PMID:9507024, GO:0002922=GO_REF:0000024, GO:2000547=GO_REF:0000024, GO:0002408=PMID:14592837, GO:0002407=PMID:15778365, GO:0050862=GO_REF:0000019, GO:0002606=GO_REF:0000024, GO:2000107=PMID:15059845, GO:0001768=PMID:12729902, GO:0045060=GO_REF:0000019, GO:0016021=GO_REF:0000037} P32248 C-C chemokine receptor type 7 protein 20130413 {GO:0002885=ISS, GO:0071731=IC, GO:0046330=IC, GO:0051491=IC, GO:2000510=ISS, GO:2000147=IC, GO:0031529=IC, GO:0005622=IDA, GO:0032649=ISS, GO:0006935=IEA, GO:0043552=IC, GO:0030838=IC, GO:0034695=IC, GO:0045860=IC, GO:0032496=IEA, GO:0031274=IC, GO:0070374=IC, GO:0043123=IC, GO:2000525=ISS, GO:2000526=ISS, GO:0051209=IC, GO:0004930=TAS, GO:0032862=IC, GO:2000522=ISS, GO:0045785=IC, GO:0007186=TAS, GO:0090023=IDA, GO:0016493=ISS, GO:0050706=ISS, GO:0035758=IPI, GO:0009897=IEA, GO:0001954=IC, GO:0035757=IPI, GO:0051897=IC, GO:0005886=IDA, GO:0032735=ISS, GO:0097022=TAS, GO:0097029=ISS, GO:0007204=TAS, GO:0006955=IEA, GO:0006954=NAS, GO:0072610=ISS, GO:0038115=IDA, GO:0038116=IDA, GO:0002922=ISS, GO:2000547=ISS, GO:0002408=IC, GO:0002407=IC, GO:0050862=IEA, GO:0002606=ISS, GO:2000107=IC, GO:0001768=IC, GO:0045060=IEA, GO:0016021=IEA} G-protein coupled receptor signaling pathway, activation of Rho GTPase activity, chemokine (C-C motif) ligand 19 signaling pathway, chemokine (C-C motif) ligand 21 signaling pathway, chemotaxis, dendritic cell chemotaxis, elevation of cytosolic calcium ion concentration, establishment of T cell polarity, immune response, inflammatory response, interleukin-12 secretion, lymphocyte migration into lymph node, mature dendritic cell differentiation, myeloid dendritic cell chemotaxis, negative regulation of leukocyte apoptotic process, negative thymic T cell selection, positive regulation of ERK1 and ERK2 cascade, positive regulation of I-kappaB kinase/NF-kappaB cascade, positive regulation of JNK cascade, positive regulation of T cell costimulation, positive regulation of T cell receptor signaling pathway, positive regulation of actin filament polymerization, positive regulation of cell adhesion, positive regulation of cell motility, positive regulation of cell-matrix adhesion, positive regulation of dendritic cell antigen processing and presentation, positive regulation of dendritic cell chemotaxis, positive regulation of filopodium assembly, positive regulation of glycoprotein biosynthetic process involved in immunological synapse formation, positive regulation of humoral immune response, positive regulation of hypersensitivity, positive regulation of immunological synapse formation, positive regulation of interleukin-12 production, positive regulation of neutrophil chemotaxis, positive regulation of phosphatidylinositol 3-kinase activity, positive regulation of protein kinase B signaling cascade, positive regulation of protein kinase activity, positive regulation of pseudopodium assembly, regulation of dendritic cell dendrite assembly, regulation of interferon-gamma production, regulation of interleukin-1 beta secretion, release of sequestered calcium ion into cytosol, response to lipopolysaccharide, response to nitric oxide, response to prostaglandin E stimulus, ruffle organization external side of plasma membrane, integral to membrane, intracellular, plasma membrane C-C chemokine receptor activity, G-protein coupled receptor activity, chemokine (C-C motif) ligand 19 binding, chemokine (C-C motif) ligand 21 binding Human CCR8 UniProtKB UniProtKB {GO:0070098=PMID:9417093, GO:0005886=Reactome:REACT_22289, GO:0015026=PMID:9417093, GO:0007204=GO_REF:0000002, GO:0019957=GO_REF:0000002, GO:0006955=GO_REF:0000002, GO:0006935=GO_REF:0000002, GO:0007186=PMID:8816377, GO:0005887=PMID:8816377, GO:0004950=PMID:9417093, GO:0016493=GO_REF:0000002, GO:0016021=GO_REF:0000038, GO:0007155=PMID:10910894} Q3KNR3 C-C chemokine receptor type 8 protein 20130413 {GO:0070098=TAS, GO:0005886=TAS, GO:0015026=TAS, GO:0007204=IEA, GO:0019957=IEA, GO:0006955=IEA, GO:0006935=IEA, GO:0007186=TAS, GO:0005887=TAS, GO:0004950=TAS, GO:0016493=IEA, GO:0016021=IEA, GO:0007155=TAS} G-protein coupled receptor signaling pathway, cell adhesion, chemokine-mediated signaling pathway, chemotaxis, elevation of cytosolic calcium ion concentration, immune response integral to membrane, integral to plasma membrane, plasma membrane C-C chemokine binding, C-C chemokine receptor activity, chemokine receptor activity, coreceptor activity Human UniProtKB-KW:KW-0812 CCR9 GOC UniProtKB {GO:0006968=PMID:10544196, GO:0006955=GO_REF:0000002, GO:0070098=PMID:10229797, GO:0005886=Reactome:REACT_22289, GO:0007186=PMID:10544196, GO:0006935=GO_REF:0000019, GO:0005887=PMID:10229797, GO:0004950=PMID:10229797, GO:0016493=GO_REF:0000019, GO:0007204=GO_REF:0000002, GO:0019957=GO_REF:0000002} P51686 C-C chemokine receptor type 9 protein 20130413 {GO:0006968=TAS, GO:0006955=IEA, GO:0070098=TAS, GO:0005886=TAS, GO:0007186=TAS, GO:0006935=IEA, GO:0005887=TAS, GO:0004950=TAS, GO:0016493=IEA, GO:0007204=IEA, GO:0019957=IEA} G-protein coupled receptor signaling pathway, cellular defense response, chemokine-mediated signaling pathway, chemotaxis, elevation of cytosolic calcium ion concentration, immune response integral to plasma membrane, plasma membrane C-C chemokine binding, C-C chemokine receptor activity, chemokine receptor activity Human CCRL1 GOC UniProtKB {GO:0006955=PMID:10706668, GO:0070098=PMID:10706668, GO:0005886=Reactome:REACT_21379, GO:0007186=PMID:10734104, GO:0006935=GO_REF:0000002, GO:0005887=PMID:10767544, GO:0004950=GO_REF:0000002, GO:0019956=GO_REF:0000002, GO:0005044=GO_REF:0000002} Q9NPB9 C-C chemokine receptor type 11 protein 20130413 {GO:0006955=TAS, GO:0070098=TAS, GO:0005886=TAS, GO:0007186=TAS, GO:0006935=IEA, GO:0005887=TAS, GO:0004950=IEA, GO:0019956=IEA, GO:0005044=IEA} G-protein coupled receptor signaling pathway, chemokine-mediated signaling pathway, chemotaxis, immune response integral to plasma membrane, plasma membrane chemokine binding, chemokine receptor activity, scavenger receptor activity Human CCS GOC UniProtKB {GO:0005515=PMID:20154138, GO:0051353=GO_REF:0000019, GO:0005507=PMID:9726962, GO:0006801=PMID:9295278, GO:0005743=GO_REF:0000033, GO:0005634=PMID:9726962, GO:0016532=GO_REF:0000033, GO:0035434=PMID:9726962, GO:0030001=GO_REF:0000002, GO:0046872=GO_REF:0000002, GO:0005829=GO_REF:0000033, GO:0015680=GO_REF:0000033, GO:0005737=PMID:9726962, GO:0005375=PMID:9726962, GO:0019430=GO_REF:0000033, GO:0008270=GO_REF:0000033, GO:0055114=GO_REF:0000002, GO:0004784=GO_REF:0000033} O14618 Copper chaperone for superoxide dismutase protein 20130413 {GO:0005515=IPI, GO:0051353=IEA, GO:0005507=TAS, GO:0006801=TAS, GO:0005743=IBA, GO:0005634=IDA, GO:0016532=IBA, GO:0035434=TAS, GO:0030001=IEA, GO:0046872=IEA, GO:0005829=IBA, GO:0015680=IBA, GO:0005737=IDA, GO:0005375=TAS, GO:0019430=IBA, GO:0008270=IBA, GO:0055114=IEA, GO:0004784=IBA} copper ion transmembrane transport, intracellular copper ion transport, metal ion transport, oxidation-reduction process, positive regulation of oxidoreductase activity, removal of superoxide radicals, superoxide metabolic process cytoplasm, cytosol, mitochondrial inner membrane, nucleus copper ion binding, copper ion transmembrane transporter activity, metal ion binding, protein binding, superoxide dismutase activity, superoxide dismutase copper chaperone activity, zinc ion binding Human CCT2 HPA UniProtKB {GO:0005515=PMID:22500027, GO:0005832=GO_REF:0000019, GO:0005874=PMID:21525035, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0005524=GO_REF:0000037, GO:0005829=Reactome:REACT_16980, GO:0005737=GO_REF:0000052, GO:0006457=Reactome:REACT_17004, GO:0051084=Reactome:REACT_16952, GO:0051082=PMID:11532003, GO:0051131=PMID:20080638, GO:0044267=Reactome:REACT_17015} P78371 T-complex protein 1 subunit beta protein 20101115 {GO:0005515=IPI, GO:0005832=IEA, GO:0005874=IDA, GO:0005730=IDA, GO:0005634=IDA, GO:0005524=IEA, GO:0005829=TAS, GO:0005737=IDA, GO:0006457=TAS, GO:0051084=TAS, GO:0051082=NAS, GO:0051131=IMP, GO:0044267=TAS} 'de novo' posttranslational protein folding, cellular protein metabolic process, chaperone-mediated protein complex assembly, protein folding chaperonin-containing T-complex, cytoplasm, cytosol, microtubule, nucleolus, nucleus ATP binding, protein binding, unfolded protein binding Human CCT3 InterPro UniProtKB {GO:0005515=PMID:12620389, GO:0005737=GO_REF:0000052, GO:0005886=GO_REF:0000052, GO:0005832=GO_REF:0000019, GO:0006457=GO_REF:0000002, GO:0005874=PMID:21525035, GO:0051084=Reactome:REACT_16952, GO:0051082=GO_REF:0000002, GO:0005856=PMID:8001976, GO:0044267=Reactome:REACT_17015, GO:0005524=GO_REF:0000002, GO:0005829=Reactome:REACT_16980} Q5SZX9 T-complex protein 1 subunit gamma protein 20130413 {GO:0005515=IPI, GO:0005737=IDA, GO:0005886=IDA, GO:0005832=IEA, GO:0006457=IEA, GO:0005874=IDA, GO:0051084=TAS, GO:0051082=IEA, GO:0005856=TAS, GO:0044267=TAS, GO:0005524=IEA, GO:0005829=TAS} 'de novo' posttranslational protein folding, cellular protein metabolic process, protein folding chaperonin-containing T-complex, cytoplasm, cytoskeleton, cytosol, microtubule, plasma membrane ATP binding, protein binding, unfolded protein binding Human InterPro:IPR002194|InterPro:IPR012719 CCT4 HPA UniProtKB {GO:0042470=GO_REF:0000039, GO:0005813=PMID:20080638, GO:0005832=GO_REF:0000019, GO:0005874=PMID:21525035, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0005524=GO_REF:0000037, GO:0005829=Reactome:REACT_16980, GO:0005737=GO_REF:0000052, GO:0006457=Reactome:REACT_17004, GO:0051084=Reactome:REACT_16952, GO:0051082=GO_REF:0000002, GO:0044267=Reactome:REACT_17015} P50991 T-complex protein 1 subunit delta protein 20101115 {GO:0042470=IEA, GO:0005813=IDA, GO:0005832=IEA, GO:0005874=IDA, GO:0005730=IDA, GO:0005634=IDA, GO:0005524=IEA, GO:0005829=TAS, GO:0005737=IDA, GO:0006457=TAS, GO:0051084=TAS, GO:0051082=IEA, GO:0044267=TAS} 'de novo' posttranslational protein folding, cellular protein metabolic process, protein folding centrosome, chaperonin-containing T-complex, cytoplasm, cytosol, melanosome, microtubule, nucleolus, nucleus ATP binding, unfolded protein binding Human CCT5 HPA UniProtKB {GO:0005813=PMID:20080638, GO:0005737=GO_REF:0000052, GO:0005832=GO_REF:0000019, GO:0006457=Reactome:REACT_17004, GO:0005874=PMID:21525035, GO:0005730=GO_REF:0000052, GO:0051084=Reactome:REACT_16952, GO:0051082=GO_REF:0000002, GO:0009615=PMID:16548883, GO:0044267=Reactome:REACT_17015, GO:0005524=GO_REF:0000037, GO:0005829=Reactome:REACT_16980} P48643 T-complex protein 1 subunit epsilon protein 20101115 {GO:0005813=IDA, GO:0005737=IDA, GO:0005832=IEA, GO:0006457=TAS, GO:0005874=IDA, GO:0005730=IDA, GO:0051084=TAS, GO:0051082=IEA, GO:0009615=IEP, GO:0044267=TAS, GO:0005524=IEA, GO:0005829=TAS} 'de novo' posttranslational protein folding, cellular protein metabolic process, protein folding, response to virus centrosome, chaperonin-containing T-complex, cytoplasm, cytosol, microtubule, nucleolus ATP binding, unfolded protein binding Human CCT6A Reactome UniProtKB {GO:0005737=PMID:8034610, GO:0005832=GO_REF:0000019, GO:0006457=Reactome:REACT_17004, GO:0005874=PMID:21525035, GO:0051084=Reactome:REACT_16952, GO:0051082=GO_REF:0000002, GO:0044267=Reactome:REACT_17015, GO:0005524=GO_REF:0000037, GO:0005829=Reactome:REACT_16980} P40227 T-complex protein 1 subunit zeta protein 20130213 {GO:0005737=TAS, GO:0005832=IEA, GO:0006457=TAS, GO:0005874=IDA, GO:0051084=TAS, GO:0051082=IEA, GO:0044267=TAS, GO:0005524=IEA, GO:0005829=TAS} 'de novo' posttranslational protein folding, cellular protein metabolic process, protein folding chaperonin-containing T-complex, cytoplasm, cytosol, microtubule ATP binding, unfolded protein binding Human CCT6B GOC UniProtKB {GO:0005737=GO_REF:0000039, GO:0006457=GO_REF:0000002, GO:0008565=PMID:8812458, GO:0007283=PMID:8812458, GO:0051082=GO_REF:0000002, GO:0015031=PMID:8812458, GO:0051131=PMID:8812458, GO:0005524=GO_REF:0000037} Q92526 T-complex protein 1 subunit zeta-2 protein 20130413 {GO:0005737=IEA, GO:0006457=IEA, GO:0008565=TAS, GO:0007283=TAS, GO:0051082=IEA, GO:0015031=TAS, GO:0051131=TAS, GO:0005524=IEA} chaperone-mediated protein complex assembly, protein folding, protein transport, spermatogenesis cytoplasm ATP binding, protein transporter activity, unfolded protein binding Human CCT7 HPA UniProtKB {GO:0005739=GO_REF:0000019, GO:0005737=GO_REF:0000052, GO:0005832=GO_REF:0000019, GO:0006457=Reactome:REACT_17004, GO:0005874=PMID:21525035, GO:0051084=Reactome:REACT_16952, GO:0051082=GO_REF:0000002, GO:0044267=Reactome:REACT_17015, GO:0005524=GO_REF:0000037, GO:0005829=Reactome:REACT_16980, GO:0042802=GO_REF:0000019} Q99832 T-complex protein 1 subunit eta protein 20080818 {GO:0005739=IEA, GO:0005737=IDA, GO:0005832=IEA, GO:0006457=TAS, GO:0005874=IDA, GO:0051084=TAS, GO:0051082=IEA, GO:0044267=TAS, GO:0005524=IEA, GO:0005829=TAS, GO:0042802=IEA} 'de novo' posttranslational protein folding, cellular protein metabolic process, protein folding chaperonin-containing T-complex, cytoplasm, cytosol, microtubule, mitochondrion ATP binding, identical protein binding, unfolded protein binding Human CCT8 HPA UniProtKB {GO:0005813=PMID:20080638, GO:0005737=GO_REF:0000052, GO:0042623=PMID:7890169, GO:0016235=GO_REF:0000052, GO:0006457=Reactome:REACT_17004, GO:0005874=PMID:21525035, GO:0051084=Reactome:REACT_16952, GO:0045111=GO_REF:0000052, GO:0051082=GO_REF:0000002, GO:0044267=Reactome:REACT_17015, GO:0005524=GO_REF:0000037, GO:0005829=Reactome:REACT_16980} P50990 T-complex protein 1 subunit theta protein 20101115 {GO:0005813=IDA, GO:0005737=IDA, GO:0042623=TAS, GO:0016235=IDA, GO:0006457=TAS, GO:0005874=IDA, GO:0051084=TAS, GO:0045111=IDA, GO:0051082=IEA, GO:0044267=TAS, GO:0005524=IEA, GO:0005829=TAS} 'de novo' posttranslational protein folding, cellular protein metabolic process, protein folding aggresome, centrosome, cytoplasm, cytosol, intermediate filament cytoskeleton, microtubule ATP binding, ATPase activity, coupled, unfolded protein binding Human CCZ1 UniProtKB UniProtKB {GO:0005765=GO_REF:0000039} P86791 Vacuolar fusion protein CCZ1 homolog protein 20130413 {GO:0005765=IEA} lysosomal membrane Human UniProtKB-SubCell:SL-0157 CCZ1B UniProtKB UniProtKB {GO:0005765=GO_REF:0000039} P86790 Vacuolar fusion protein CCZ1 homolog B protein 20130413 {GO:0005765=IEA} lysosomal membrane Human UniProtKB-SubCell:SL-0157 CD101 PINC UniProtKB {GO:0005886=PMID:7722300, GO:0016812=GO_REF:0000002, GO:0016021=GO_REF:0000037, GO:0007166=PMID:7722300} Q93033 Immunoglobulin superfamily member 2 protein 20030904 {GO:0005886=TAS, GO:0016812=IEA, GO:0016021=IEA, GO:0007166=TAS} cell surface receptor signaling pathway integral to membrane, plasma membrane hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides Human CD109 UniProtKB UniProtKB {GO:0005886=GO_REF:0000039, GO:0004867=GO_REF:0000037, GO:0031225=GO_REF:0000037, GO:0005615=GO_REF:0000002} Q6YHK3 CD109 antigen protein 20130413 {GO:0005886=IEA, GO:0004867=IEA, GO:0031225=IEA, GO:0005615=IEA} anchored to membrane, extracellular space, plasma membrane serine-type endopeptidase inhibitor activity Human UniProtKB-SubCell:SL-0039 CD14 BHF-UCL UniProtKB {GO:0006909=PMID:9548256, GO:0034142=Reactome:REACT_6894, GO:0009408=GO_REF:0000019, GO:0005886=Reactome:REACT_150423, GO:0070891=PMID:12594207, GO:0007249=Reactome:REACT_25351, GO:0031225=GO_REF:0000037, GO:0050715=GO_REF:0000019, GO:0005615=GO_REF:0000019, GO:0045807=GO_REF:0000019, GO:0002756=Reactome:REACT_6809, GO:0006954=GO_REF:0000019, GO:0002755=Reactome:REACT_6788, GO:0032496=GO_REF:0000019, GO:0034138=Reactome:REACT_6783, GO:0038124=Reactome:REACT_8006, GO:0016019=PMID:8798531, GO:0038123=Reactome:REACT_8005, GO:0009986=GO_REF:0000019, GO:0032760=PMID:12594207, GO:0001847=PMID:2402637, GO:0034134=Reactome:REACT_7980, GO:0006915=PMID:9548256, GO:0005576=Reactome:REACT_150423, GO:0002224=Reactome:REACT_6966, GO:0001530=PMID:12594207, GO:0071223=PMID:12594207, GO:0071222=PMID:12594207, GO:0045087=Reactome:REACT_6802, GO:0035666=Reactome:REACT_25281, GO:0045121=GO_REF:0000019, GO:0007166=PMID:8798531, GO:0010008=Reactome:REACT_150447} P08571 Monocyte differentiation antigen CD14 protein 20080707 {GO:0006909=TAS, GO:0034142=TAS, GO:0009408=IEA, GO:0005886=TAS, GO:0070891=IDA, GO:0007249=TAS, GO:0031225=IEA, GO:0050715=IEA, GO:0005615=IEA, GO:0045807=IEA, GO:0002756=TAS, GO:0006954=IEA, GO:0002755=TAS, GO:0032496=IEA, GO:0034138=TAS, GO:0038124=TAS, GO:0016019=TAS, GO:0038123=TAS, GO:0009986=IEA, GO:0032760=IDA, GO:0001847=TAS, GO:0034134=TAS, GO:0006915=TAS, GO:0005576=TAS, GO:0002224=TAS, GO:0001530=IDA, GO:0071223=IDA, GO:0071222=IDA, GO:0045087=TAS, GO:0035666=TAS, GO:0045121=IEA, GO:0007166=TAS, GO:0010008=TAS} I-kappaB kinase/NF-kappaB cascade, MyD88-dependent toll-like receptor signaling pathway, MyD88-independent toll-like receptor signaling pathway, TRIF-dependent toll-like receptor signaling pathway, apoptotic process, cell surface receptor signaling pathway, cellular response to lipopolysaccharide, cellular response to lipoteichoic acid, inflammatory response, innate immune response, phagocytosis, positive regulation of cytokine secretion, positive regulation of endocytosis, positive regulation of tumor necrosis factor production, response to heat, response to lipopolysaccharide, toll-like receptor 2 signaling pathway, toll-like receptor 3 signaling pathway, toll-like receptor 4 signaling pathway, toll-like receptor TLR1:TLR2 signaling pathway, toll-like receptor TLR6:TLR2 signaling pathway, toll-like receptor signaling pathway anchored to membrane, cell surface, endosome membrane, extracellular region, extracellular space, membrane raft, plasma membrane lipopolysaccharide binding, lipoteichoic acid binding, opsonin receptor activity, peptidoglycan receptor activity Human CD151 Reactome UniProtKB {GO:0005515=PMID:14676841, GO:0005886=Reactome:REACT_150217, GO:0016020=PMID:8627808, GO:0042098=GO_REF:0000019, GO:0016477=GO_REF:0000019, GO:0030198=Reactome:REACT_118779, GO:0005887=PMID:8627808, GO:0034329=Reactome:REACT_20676, GO:0031581=Reactome:REACT_20537, GO:0016021=GO_REF:0000038, GO:0007155=PMID:9602068, GO:0005829=Reactome:REACT_20665} P48509 CD151 antigen protein 20130213 {GO:0005515=IPI, GO:0005886=TAS, GO:0016020=TAS, GO:0042098=IEA, GO:0016477=IEA, GO:0030198=TAS, GO:0005887=TAS, GO:0034329=TAS, GO:0031581=TAS, GO:0016021=IEA, GO:0007155=NAS, GO:0005829=TAS} T cell proliferation, cell adhesion, cell junction assembly, cell migration, extracellular matrix organization, hemidesmosome assembly cytosol, integral to membrane, integral to plasma membrane, membrane, plasma membrane protein binding Human CD160 Reactome UniProtKB {GO:0006968=PMID:9743336, GO:0005886=Reactome:REACT_11106, GO:0008283=PMID:9973372, GO:0050776=Reactome:REACT_11152, GO:0005102=PMID:9973372, GO:0004872=PMID:9973372, GO:0046658=PMID:9973372, GO:0007166=PMID:9973372, GO:0032393=PMID:15494480} O95971 CD160 antigen protein 20070516 {GO:0006968=TAS, GO:0005886=TAS, GO:0008283=TAS, GO:0050776=TAS, GO:0005102=IDA, GO:0004872=TAS, GO:0046658=IDA, GO:0007166=TAS, GO:0032393=IDA} cell proliferation, cell surface receptor signaling pathway, cellular defense response, regulation of immune response anchored to plasma membrane, plasma membrane MHC class I receptor activity, receptor activity, receptor binding Human CD163 Reactome UniProtKB {GO:0030666=Reactome:REACT_160193, GO:0005515=PMID:15479433, GO:0005886=Reactome:REACT_160225, GO:0016020=GO_REF:0000002, GO:0005887=PMID:8370408, GO:0005576=GO_REF:0000029, GO:0006953=GO_REF:0000037, GO:0005044=PMID:8370408} Q86VB7 Scavenger receptor cysteine-rich type 1 protein M130 protein 20120506 {GO:0030666=TAS, GO:0005515=IPI, GO:0005886=TAS, GO:0016020=IEA, GO:0005887=TAS, GO:0005576=NAS, GO:0006953=IEA, GO:0005044=NAS} acute-phase response endocytic vesicle membrane, extracellular region, integral to plasma membrane, membrane, plasma membrane protein binding, scavenger receptor activity Human CD164 PINC UniProtKB {GO:0030097=PMID:11027692, GO:0005515=PMID:17077324, GO:0008285=PMID:10878358, GO:0005886=PMID:10491205, GO:0007275=PMID:9680353, GO:0005576=GO_REF:0000039, GO:0005765=GO_REF:0000039, GO:0005764=PMID:11027692, GO:0007165=PMID:9763543, GO:0007162=PMID:10878358, GO:0006955=PMID:9763543, GO:0007517=GO_REF:0000037, GO:0005887=PMID:11027692, GO:0007155=PMID:10491205, GO:0007157=PMID:10491205, GO:0010008=GO_REF:0000039, GO:0005768=PMID:11027692} Q04900 Sialomucin core protein 24 protein 20030904 {GO:0030097=NAS, GO:0005515=IPI, GO:0008285=NAS, GO:0005886=IDA, GO:0007275=TAS, GO:0005576=IEA, GO:0005765=IEA, GO:0005764=IDA, GO:0007165=TAS, GO:0007162=NAS, GO:0006955=TAS, GO:0007517=IEA, GO:0005887=NAS, GO:0007155=IDA, GO:0007157=IDA, GO:0010008=IEA, GO:0005768=IDA} cell adhesion, hemopoiesis, heterophilic cell-cell adhesion, immune response, multicellular organismal development, muscle organ development, negative regulation of cell adhesion, negative regulation of cell proliferation, signal transduction endosome, endosome membrane, extracellular region, integral to plasma membrane, lysosomal membrane, lysosome, plasma membrane protein binding Human CD177 Reactome UniProtKB {GO:0005886=Reactome:REACT_12006, GO:0007596=Reactome:REACT_604, GO:0031225=GO_REF:0000037, GO:0050900=Reactome:REACT_12051} Q8N6Q3 CD177 antigen protein 20071111 {GO:0005886=TAS, GO:0007596=TAS, GO:0031225=IEA, GO:0050900=TAS} blood coagulation, leukocyte migration anchored to membrane, plasma membrane Human CD180 MGI UniProtKB {GO:0006954=GO_REF:0000037, GO:0005886=GO_REF:0000039, GO:0045087=GO_REF:0000037, GO:0031666=PMID:10880523, GO:0016021=GO_REF:0000037} Q99467 CD180 antigen protein 20130227 {GO:0006954=IEA, GO:0005886=IEA, GO:0045087=IEA, GO:0031666=IGI, GO:0016021=IEA} inflammatory response, innate immune response, positive regulation of lipopolysaccharide-mediated signaling pathway integral to membrane, plasma membrane Human UniProtKB:O95711 CD19 Reactome UniProtKB {GO:0050853=GO_REF:0000019, GO:0048011=Reactome:REACT_11061, GO:0005886=Reactome:REACT_147854, GO:0048015=Reactome:REACT_12464, GO:0006968=PMID:1373518, GO:0007173=Reactome:REACT_9417, GO:0005887=PMID:2472450, GO:0008543=Reactome:REACT_9470, GO:0045087=Reactome:REACT_6802, GO:0050776=Reactome:REACT_11152, GO:0005057=PMID:1373518, GO:0009897=PMID:20660734, GO:0007166=PMID:1714482} P15391 B-lymphocyte antigen CD19 protein 20120127 {GO:0050853=IEA, GO:0048011=TAS, GO:0005886=TAS, GO:0048015=TAS, GO:0006968=TAS, GO:0007173=TAS, GO:0005887=TAS, GO:0008543=TAS, GO:0045087=TAS, GO:0050776=TAS, GO:0005057=TAS, GO:0009897=IDA, GO:0007166=TAS} B cell receptor signaling pathway, cell surface receptor signaling pathway, cellular defense response, epidermal growth factor receptor signaling pathway, fibroblast growth factor receptor signaling pathway, innate immune response, neurotrophin TRK receptor signaling pathway, phosphatidylinositol-mediated signaling, regulation of immune response external side of plasma membrane, integral to plasma membrane, plasma membrane receptor signaling protein activity Human CD1A IntAct UniProtKB {GO:0005515=PMID:15723809, GO:0006955=PMID:2447586, GO:0005887=PMID:2447586, GO:0019882=GO_REF:0000002, GO:0042612=GO_REF:0000002, GO:0010008=GO_REF:0000039} P06126 T-cell surface glycoprotein CD1a protein 20130415 {GO:0005515=IPI, GO:0006955=NAS, GO:0005887=NAS, GO:0019882=IEA, GO:0042612=IEA, GO:0010008=IEA} antigen processing and presentation, immune response MHC class I protein complex, endosome membrane, integral to plasma membrane protein binding Human UniProtKB:P61769 CD1B IntAct UniProtKB {GO:0005515=PMID:14764708, GO:0006955=GO_REF:0000002, GO:0005886=GO_REF:0000039, GO:0016020=GO_REF:0000002, GO:0019882=GO_REF:0000002, GO:0016021=GO_REF:0000037, GO:0005765=GO_REF:0000039, GO:0010008=GO_REF:0000039} P29016 T-cell surface glycoprotein CD1b protein 20130415 {GO:0005515=IPI, GO:0006955=IEA, GO:0005886=IEA, GO:0016020=IEA, GO:0019882=IEA, GO:0016021=IEA, GO:0005765=IEA, GO:0010008=IEA} antigen processing and presentation, immune response endosome membrane, integral to membrane, lysosomal membrane, membrane, plasma membrane protein binding Human UniProtKB:P61769 CD1C PINC UniProtKB {GO:0071723=PMID:21167756, GO:0006955=GO_REF:0000002, GO:0051861=PMID:21167756, GO:0005886=PMID:2447586, GO:0016020=GO_REF:0000002, GO:0005887=PMID:1702817, GO:0019882=GO_REF:0000002, GO:0030884=PMID:21167756, GO:0030883=PMID:21167756, GO:0002286=PMID:21167756, GO:0010008=GO_REF:0000039} P29017 T-cell surface glycoprotein CD1c protein 20030904 {GO:0071723=IDA, GO:0006955=IEA, GO:0051861=IDA, GO:0005886=TAS, GO:0016020=IEA, GO:0005887=TAS, GO:0019882=IEA, GO:0030884=IDA, GO:0030883=IDA, GO:0002286=IDA, GO:0010008=IEA} T cell activation involved in immune response, antigen processing and presentation, immune response endosome membrane, integral to plasma membrane, membrane, plasma membrane endogenous lipid antigen binding, exogenous lipid antigen binding, glycolipid binding, lipopeptide binding Human CD1D BHF-UCL UniProtKB {GO:0030882=PMID:19124746, GO:0030881=PMID:14500461, GO:0043499=PMID:19124746, GO:0009986=PMID:19124746, GO:0030884=PMID:10523605, GO:0005765=GO_REF:0000039, GO:0045058=PMID:14500461, GO:0042393=PMID:20363964, GO:0005737=PMID:19124746, GO:0045089=PMID:14500461, GO:0005887=PMID:11315191, GO:0019048=GO_REF:0000037, GO:0045087=GO_REF:0000037, GO:0042102=PMID:19124746, GO:0048006=PMID:10523605, GO:0034113=PMID:19124746, GO:0004872=PMID:11315191, GO:0050839=PMID:19124746, GO:0016045=PMID:14500461, GO:0010008=GO_REF:0000039} P15813 Antigen-presenting glycoprotein CD1d protein 20111125 {GO:0030882=IDA, GO:0030881=TAS, GO:0043499=IDA, GO:0009986=IDA, GO:0030884=IDA, GO:0005765=IEA, GO:0045058=TAS, GO:0042393=IPI, GO:0005737=IDA, GO:0045089=TAS, GO:0005887=TAS, GO:0019048=IEA, GO:0045087=IEA, GO:0042102=IDA, GO:0048006=IDA, GO:0034113=TAS, GO:0004872=IC, GO:0050839=IPI, GO:0016045=TAS, GO:0010008=IEA} T cell selection, antigen processing and presentation, endogenous lipid antigen via MHC class Ib, detection of bacterium, heterotypic cell-cell adhesion, innate immune response, positive regulation of T cell proliferation, positive regulation of innate immune response, virus-host interaction cell surface, cytoplasm, endosome membrane, integral to plasma membrane, lysosomal membrane beta-2-microglobulin binding, cell adhesion molecule binding, eukaryotic cell surface binding, exogenous lipid antigen binding, histone binding, lipid antigen binding, receptor activity Human CD1E UniProtKB UniProtKB {GO:0006955=PMID:2467814, GO:0000139=GO_REF:0000039, GO:0016020=GO_REF:0000002, GO:0005887=PMID:2467814, GO:0005770=GO_REF:0000039, GO:0019882=GO_REF:0000002, GO:0005769=GO_REF:0000039, GO:0043202=GO_REF:0000039} P15812 T-cell surface glycoprotein CD1e, membrane-associated protein 20010912 {GO:0006955=NAS, GO:0000139=IEA, GO:0016020=IEA, GO:0005887=NAS, GO:0005770=IEA, GO:0019882=IEA, GO:0005769=IEA, GO:0043202=IEA} antigen processing and presentation, immune response Golgi membrane, early endosome, integral to plasma membrane, late endosome, lysosomal lumen, membrane Human CD2 InterPro UniProtKB {GO:0005515=PMID:1970422, GO:0043499=GO_REF:0000019, GO:0005886=Reactome:REACT_12031, GO:0005576=GO_REF:0000019, GO:0030887=PMID:12714509, GO:0006917=PMID:9270771, GO:0050900=Reactome:REACT_12051, GO:0042803=GO_REF:0000019, GO:0016337=PMID:7544493, GO:0042110=PMID:2471997, GO:0030101=PMID:12714509, GO:0007596=Reactome:REACT_604, GO:0005887=PMID:7544493, GO:0045580=PMID:11544295, GO:0009898=GO_REF:0000019, GO:0001766=PMID:11376005, GO:0004872=GO_REF:0000002, GO:0016021=GO_REF:0000002, GO:0046658=GO_REF:0000019, GO:0009897=PMID:21460847, GO:0007166=PMID:10575274} Q5JVN7 T-cell surface antigen CD2 protein 20130413 {GO:0005515=IPI, GO:0043499=IEA, GO:0005886=TAS, GO:0005576=IEA, GO:0030887=NAS, GO:0006917=TAS, GO:0050900=TAS, GO:0042803=IEA, GO:0016337=NAS, GO:0042110=TAS, GO:0030101=NAS, GO:0007596=TAS, GO:0005887=NAS, GO:0045580=NAS, GO:0009898=IEA, GO:0001766=TAS, GO:0004872=IEA, GO:0016021=IEA, GO:0046658=IEA, GO:0009897=IDA, GO:0007166=TAS} T cell activation, blood coagulation, cell surface receptor signaling pathway, cell-cell adhesion, induction of apoptosis, leukocyte migration, membrane raft polarization, natural killer cell activation, positive regulation of myeloid dendritic cell activation, regulation of T cell differentiation anchored to plasma membrane, external side of plasma membrane, extracellular region, integral to membrane, integral to plasma membrane, internal side of plasma membrane, plasma membrane eukaryotic cell surface binding, protein binding, protein homodimerization activity, receptor activity Human InterPro:IPR015631 CD200 IntAct UniProtKB {GO:0005515=PMID:21982860, GO:0005886=Reactome:REACT_11188, GO:0005887=PMID:3032785, GO:0050776=Reactome:REACT_11152} P41217 OX-2 membrane glycoprotein protein 20130415 {GO:0005515=IPI, GO:0005886=TAS, GO:0005887=TAS, GO:0050776=TAS} regulation of immune response integral to plasma membrane, plasma membrane protein binding Human UniProtKB:Q8TD46 CD200R1 IntAct UniProtKB {GO:0005515=PMID:21982860, GO:0005886=Reactome:REACT_11188, GO:0016020=GO_REF:0000038, GO:0019048=GO_REF:0000037, GO:0050776=Reactome:REACT_11152, GO:0005576=GO_REF:0000039, GO:0016021=GO_REF:0000037} Q8TD46 Cell surface glycoprotein CD200 receptor 1 protein 20130415 {GO:0005515=IPI, GO:0005886=TAS, GO:0016020=IEA, GO:0019048=IEA, GO:0050776=TAS, GO:0005576=IEA, GO:0016021=IEA} regulation of immune response, virus-host interaction extracellular region, integral to membrane, membrane, plasma membrane protein binding Human UniProtKB:P41217 CD209 MGI UniProtKB {GO:0019062=PMID:11337487, GO:0005886=GO_REF:0000039, GO:0009988=PMID:11337487, GO:0046790=PMID:11337487, GO:0005576=GO_REF:0000039, GO:0046795=PMID:11337487, GO:0019079=PMID:11337487, GO:0005537=PMID:1518869, GO:0046872=GO_REF:0000037, GO:0006897=GO_REF:0000037, GO:0035556=PMID:11337487, GO:0046968=PMID:11337487, GO:0005737=PMID:11337487, GO:0016020=PMID:1518869, GO:0019882=PMID:11337487, GO:0019048=PMID:11337487, GO:0045087=GO_REF:0000037, GO:0042605=PMID:11337487, GO:0042129=PMID:12456590, GO:0007159=PMID:11337487, GO:0030246=PMID:11337487, GO:0016021=GO_REF:0000037, GO:0007157=PMID:1518869} Q9NNX6 CD209 antigen protein 20120402 {GO:0019062=TAS, GO:0005886=IEA, GO:0009988=TAS, GO:0046790=TAS, GO:0005576=IEA, GO:0046795=TAS, GO:0019079=NAS, GO:0005537=TAS, GO:0046872=IEA, GO:0006897=IEA, GO:0035556=NAS, GO:0046968=NAS, GO:0005737=NAS, GO:0016020=TAS, GO:0019882=NAS, GO:0019048=TAS, GO:0045087=IEA, GO:0042605=NAS, GO:0042129=IDA, GO:0007159=NAS, GO:0030246=NAS, GO:0016021=IEA, GO:0007157=TAS} antigen processing and presentation, cell-cell recognition, endocytosis, heterophilic cell-cell adhesion, innate immune response, intracellular signal transduction, intracellular virion transport, leukocyte cell-cell adhesion, peptide antigen transport, regulation of T cell proliferation, viral attachment to host cell, viral genome replication, virus-host interaction cytoplasm, extracellular region, integral to membrane, membrane, plasma membrane carbohydrate binding, mannose binding, metal ion binding, peptide antigen binding, virion binding Human CD22 IntAct UniProtKB {GO:0005515=PMID:8647200, GO:0005887=GO_REF:0000019, GO:0007155=GO_REF:0000037, GO:0009897=GO_REF:0000019} P20273 B-cell receptor CD22 protein 20130415 {GO:0005515=IPI, GO:0005887=IEA, GO:0007155=IEA, GO:0009897=IEA} cell adhesion external side of plasma membrane, integral to plasma membrane protein binding Human UniProtKB:P43405 CD226 BHF-UCL UniProtKB {GO:0005515=PMID:21982860, GO:0008037=PMID:16304049, GO:0009986=PMID:16831868, GO:0005886=Reactome:REACT_11239, GO:0019901=PMID:16831868, GO:0033005=PMID:16831868, GO:0001816=GO_REF:0000019, GO:0007165=PMID:8673704, GO:0005178=PMID:16831868, GO:0005887=PMID:8673704, GO:0050776=Reactome:REACT_11152, GO:0045954=PMID:16304049, GO:0002860=PMID:12913096, GO:0045121=PMID:16831868, GO:0007155=GO_REF:0000037, GO:0050839=PMID:12913096, GO:0060369=PMID:16831868, GO:0002891=PMID:16831868} Q15762 CD226 antigen protein 20081127 {GO:0005515=IPI, GO:0008037=TAS, GO:0009986=IDA, GO:0005886=TAS, GO:0019901=IPI, GO:0033005=IDA, GO:0001816=IEA, GO:0007165=TAS, GO:0005178=IPI, GO:0005887=TAS, GO:0050776=TAS, GO:0045954=IMP, GO:0002860=IMP, GO:0045121=TAS, GO:0007155=IEA, GO:0050839=IPI, GO:0060369=IDA, GO:0002891=IDA} cell adhesion, cell recognition, cytokine production, positive regulation of Fc receptor mediated stimulatory signaling pathway, positive regulation of immunoglobulin mediated immune response, positive regulation of mast cell activation, positive regulation of natural killer cell mediated cytotoxicity, positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, regulation of immune response, signal transduction cell surface, integral to plasma membrane, membrane raft, plasma membrane cell adhesion molecule binding, integrin binding, protein binding, protein kinase binding Human UniProtKB:Q92692 CD24 GOC UniProtKB {GO:0005515=PMID:22731636, GO:0045730=PMID:8223854, GO:0072112=PMID:19092120, GO:0043627=PMID:10037815, GO:0005886=GO_REF:0000039, GO:0061098=PMID:11313396, GO:0031295=PMID:11272271, GO:0002237=PMID:15493995, GO:0031225=GO_REF:0000037, GO:0032597=PMID:11313396, GO:0007204=PMID:8223854, GO:0032913=PMID:16930538, GO:0072139=PMID:19092120, GO:0042104=PMID:11272271, GO:0016337=PMID:15633604, GO:0030296=PMID:11313396, GO:0030856=PMID:16930538, GO:0007411=Reactome:REACT_18266, GO:0043406=PMID:12496407, GO:0032600=GO_REF:0000024, GO:0043408=PMID:11313396, GO:0004871=PMID:8213086, GO:0016055=PMID:16532032, GO:0001775=PMID:8223854, GO:0042632=PMID:16390867, GO:0001666=PMID:15174142, GO:0009986=PMID:16532032, GO:0019901=PMID:8753773, GO:0097193=PMID:11313396, GO:2000768=PMID:16885410, GO:0042325=PMID:11313396, GO:0001959=PMID:16390867, GO:0002768=PMID:11313396, GO:0016477=PMID:16390867, GO:0016020=PMID:10037815, GO:0045121=PMID:11313396} P25063 Signal transducer CD24 protein 20130413 {GO:0005515=IPI, GO:0045730=IDA, GO:0072112=IMP, GO:0043627=IEP, GO:0005886=IEA, GO:0061098=IDA, GO:0031295=IDA, GO:0002237=ISS, GO:0031225=IEA, GO:0032597=IDA, GO:0007204=IDA, GO:0032913=IMP, GO:0072139=IMP, GO:0042104=IDA, GO:0016337=NAS, GO:0030296=IDA, GO:0030856=NAS, GO:0007411=TAS, GO:0043406=IDA, GO:0032600=ISS, GO:0043408=IDA, GO:0004871=NAS, GO:0016055=NAS, GO:0001775=IDA, GO:0042632=ISS, GO:0001666=IEP, GO:0009986=IDA, GO:0019901=IPI, GO:0097193=NAS, GO:2000768=IMP, GO:0042325=IDA, GO:0001959=ISS, GO:0002768=IC, GO:0016477=ISS, GO:0016020=IDA, GO:0045121=IDA} B cell receptor transport into membrane raft, T cell costimulation, Wnt receptor signaling pathway, axon guidance, cell activation, cell migration, cell-cell adhesion, chemokine receptor transport out of membrane raft, cholesterol homeostasis, elevation of cytosolic calcium ion concentration, glomerular parietal epithelial cell differentiation, glomerular visceral epithelial cell differentiation, immune response-regulating cell surface receptor signaling pathway, intrinsic apoptotic signaling pathway, negative regulation of transforming growth factor beta3 production, positive regulation of MAP kinase activity, positive regulation of activated T cell proliferation, positive regulation of nephron tubule epithelial cell differentiation, positive regulation of protein tyrosine kinase activity, regulation of MAPK cascade, regulation of cytokine-mediated signaling pathway, regulation of epithelial cell differentiation, regulation of phosphorylation, respiratory burst, response to estrogen stimulus, response to hypoxia, response to molecule of bacterial origin anchored to membrane, cell surface, membrane, membrane raft, plasma membrane protein binding, protein kinase binding, protein tyrosine kinase activator activity, signal transducer activity Human CD244 IntAct UniProtKB {GO:0005515=PMID:18296487, GO:0007165=PMID:10358138, GO:0005886=Reactome:REACT_12018, GO:0007596=Reactome:REACT_604, GO:0004872=GO_REF:0000002, GO:0016021=GO_REF:0000037, GO:0050900=Reactome:REACT_12051, GO:0009897=PMID:17213291} Q9BZW8 Natural killer cell receptor 2B4 protein 20130415 {GO:0005515=IPI, GO:0007165=TAS, GO:0005886=TAS, GO:0007596=TAS, GO:0004872=IEA, GO:0016021=IEA, GO:0050900=TAS, GO:0009897=IDA} blood coagulation, leukocyte migration, signal transduction external side of plasma membrane, integral to membrane, plasma membrane protein binding, receptor activity Human UniProtKB:P09326 CD247 IntAct UniProtKB {GO:0005515=PMID:16461343, GO:0050852=Reactome:REACT_12526, GO:0005886=Reactome:REACT_160316, GO:0031295=Reactome:REACT_19344, GO:0042803=PMID:12110186, GO:0042802=PMID:17055436, GO:0050690=Reactome:REACT_11068, GO:0042105=GO_REF:0000019, GO:0005737=PMID:11390434, GO:0019048=GO_REF:0000037, GO:0042101=PMID:8176201, GO:0045087=Reactome:REACT_6802, GO:0050776=Reactome:REACT_11152, GO:0016032=Reactome:REACT_6185, GO:0016021=GO_REF:0000037, GO:0038096=Reactome:REACT_160123, GO:0004888=GO_REF:0000002} P20963 T-cell surface glycoprotein CD3 zeta chain protein 20130415 {GO:0005515=IPI, GO:0050852=TAS, GO:0005886=TAS, GO:0031295=TAS, GO:0042803=NAS, GO:0042802=IPI, GO:0050690=TAS, GO:0042105=IEA, GO:0005737=IDA, GO:0019048=IEA, GO:0042101=IDA, GO:0045087=TAS, GO:0050776=TAS, GO:0016032=TAS, GO:0016021=IEA, GO:0038096=TAS, GO:0004888=IEA} Fc-gamma receptor signaling pathway involved in phagocytosis, T cell costimulation, T cell receptor signaling pathway, innate immune response, regulation of defense response to virus by virus, regulation of immune response, viral reproduction, virus-host interaction T cell receptor complex, alpha-beta T cell receptor complex, cytoplasm, integral to membrane, plasma membrane identical protein binding, protein binding, protein homodimerization activity, transmembrane signaling receptor activity Human UniProtKB:P20963 CD248 UniProtKB UniProtKB {GO:0003674=GO_REF:0000015, GO:0008150=GO_REF:0000015, GO:0005737=GO_REF:0000019, GO:0005509=GO_REF:0000002, GO:0005578=PMID:10947988, GO:0030246=GO_REF:0000002, GO:0016021=GO_REF:0000037} Q9HCU0 Endosialin protein 20111208 {GO:0003674=ND, GO:0008150=ND, GO:0005737=IEA, GO:0005509=IEA, GO:0005578=TAS, GO:0030246=IEA, GO:0016021=IEA} biological_process cytoplasm, integral to membrane, proteinaceous extracellular matrix calcium ion binding, carbohydrate binding, molecular_function Human CD27 GOC UniProtKB {GO:0005515=PMID:16683188, GO:0043066=PMID:12324477, GO:0016064=PMID:14556986, GO:0045471=GO_REF:0000019, GO:0045579=PMID:10809378, GO:0046330=GO_REF:0000024, GO:0005576=PMID:12624711, GO:0006917=PMID:9177220, GO:0008588=PMID:12324477, GO:0005887=PMID:12324477, GO:0043154=PMID:12324477, GO:0043027=PMID:12324477, GO:0007166=PMID:14556986, GO:0009897=GO_REF:0000019, GO:0004888=PMID:14556986} P26842 CD27 antigen protein 20130413 {GO:0005515=IPI, GO:0043066=IDA, GO:0016064=NAS, GO:0045471=IEA, GO:0045579=NAS, GO:0046330=ISS, GO:0005576=NAS, GO:0006917=IDA, GO:0008588=NAS, GO:0005887=NAS, GO:0043154=IDA, GO:0043027=IDA, GO:0007166=NAS, GO:0009897=IEA, GO:0004888=NAS} cell surface receptor signaling pathway, immunoglobulin mediated immune response, induction of apoptosis, negative regulation of apoptotic process, negative regulation of cysteine-type endopeptidase activity involved in apoptotic process, positive regulation of B cell differentiation, positive regulation of JNK cascade, release of cytoplasmic sequestered NF-kappaB, response to ethanol external side of plasma membrane, extracellular region, integral to plasma membrane cysteine-type endopeptidase inhibitor activity involved in apoptotic process, protein binding, transmembrane signaling receptor activity Human CD274 IntAct UniProtKB {GO:0005515=PMID:21982860, GO:0007165=PMID:10581077, GO:2001181=PMID:10581077, GO:0006955=PMID:10581077, GO:0005886=Reactome:REACT_19312, GO:0031295=Reactome:REACT_19344, GO:0042102=PMID:10581077, GO:0016021=GO_REF:0000037, GO:0007166=PMID:10581077, GO:0009897=GO_REF:0000019, GO:0012505=GO_REF:0000039, GO:0042130=GO_REF:0000019} Q9NZQ7 Programmed cell death 1 ligand 1 protein 20130415 {GO:0005515=IPI, GO:0007165=IDA, GO:2001181=IDA, GO:0006955=IDA, GO:0005886=TAS, GO:0031295=TAS, GO:0042102=TAS, GO:0016021=IEA, GO:0007166=IDA, GO:0009897=IEA, GO:0012505=IEA, GO:0042130=IEA} T cell costimulation, cell surface receptor signaling pathway, immune response, negative regulation of T cell proliferation, positive regulation of T cell proliferation, positive regulation of interleukin-10 secretion, signal transduction endomembrane system, external side of plasma membrane, integral to membrane, plasma membrane protein binding Human UniProtKB:Q15116 CD276 HGNC UniProtKB {GO:0005515=PMID:18650384, GO:0030501=GO_REF:0000019, GO:0008283=PMID:11224528, GO:0005102=PMID:11224528, GO:0042130=GO_REF:0000019, GO:0045085=GO_REF:0000019, GO:0045669=GO_REF:0000019, GO:0006955=PMID:11224528, GO:0042110=PMID:18650384, GO:0016020=GO_REF:0000038, GO:0045077=GO_REF:0000019, GO:0045078=PMID:11224528, GO:0050728=GO_REF:0000019, GO:0042102=PMID:11224528, GO:0050776=PMID:11224528, GO:0016021=PMID:15188059, GO:0009897=PMID:15188059} Q5ZPR3 CD276 antigen protein 20061106 {GO:0005515=IPI, GO:0030501=IEA, GO:0008283=NAS, GO:0005102=NAS, GO:0042130=IEA, GO:0045085=IEA, GO:0045669=IEA, GO:0006955=NAS, GO:0042110=IDA, GO:0016020=IEA, GO:0045077=IEA, GO:0045078=IDA, GO:0050728=IEA, GO:0042102=IDA, GO:0050776=NAS, GO:0016021=NAS, GO:0009897=NAS} T cell activation, cell proliferation, immune response, negative regulation of T cell proliferation, negative regulation of inflammatory response, negative regulation of interferon-gamma biosynthetic process, negative regulation of interleukin-2 biosynthetic process, positive regulation of T cell proliferation, positive regulation of bone mineralization, positive regulation of interferon-gamma biosynthetic process, positive regulation of osteoblast differentiation, regulation of immune response external side of plasma membrane, integral to membrane, membrane protein binding, receptor binding Human CD28 UniProtKB UniProtKB {GO:0005515=PMID:9784967, GO:0005886=Reactome:REACT_147854, GO:0002863=GO_REF:0000019, GO:0031295=Reactome:REACT_19344, GO:0042089=PMID:8717514, GO:0002020=PMID:12777399, GO:0042802=PMID:3159820, GO:0005829=Reactome:REACT_11164, GO:0006955=GO_REF:0000002, GO:0007173=Reactome:REACT_9417, GO:0006959=PMID:8717514, GO:0045944=GO_REF:0000019, GO:0042102=GO_REF:0000024, GO:0046641=GO_REF:0000019, GO:0016032=Reactome:REACT_6185, GO:0045070=PMID:7492435, GO:0048011=Reactome:REACT_11061, GO:0048015=Reactome:REACT_12464, GO:0045727=PMID:12028592, GO:0045840=GO_REF:0000024, GO:0015026=PMID:9784967, GO:0050690=Reactome:REACT_11149, GO:0045086=GO_REF:0000024, GO:0045066=PMID:18641304, GO:0016020=GO_REF:0000002, GO:0005887=PMID:9784967, GO:0008543=Reactome:REACT_9470, GO:0045087=Reactome:REACT_6802, GO:0005070=PMID:19641626, GO:0045060=GO_REF:0000019, GO:0048304=GO_REF:0000019, GO:0007166=PMID:9784967, GO:0009897=PMID:11390434} Q70WG0 CD28 antigen (Tp44), isoform CRA_b protein 20051214 {GO:0005515=IPI, GO:0005886=TAS, GO:0002863=IEA, GO:0031295=TAS, GO:0042089=TAS, GO:0002020=IPI, GO:0042802=NAS, GO:0005829=TAS, GO:0006955=IEA, GO:0007173=TAS, GO:0006959=TAS, GO:0045944=IEA, GO:0042102=ISS, GO:0046641=IEA, GO:0016032=TAS, GO:0045070=NAS, GO:0048011=TAS, GO:0048015=TAS, GO:0045727=NAS, GO:0045840=ISS, GO:0015026=TAS, GO:0050690=TAS, GO:0045086=ISS, GO:0045066=IDA, GO:0016020=IEA, GO:0005887=TAS, GO:0008543=TAS, GO:0045087=TAS, GO:0005070=IDA, GO:0045060=IEA, GO:0048304=IEA, GO:0007166=TAS, GO:0009897=IDA} T cell costimulation, cell surface receptor signaling pathway, cytokine biosynthetic process, epidermal growth factor receptor signaling pathway, fibroblast growth factor receptor signaling pathway, humoral immune response, immune response, innate immune response, negative thymic T cell selection, neurotrophin TRK receptor signaling pathway, phosphatidylinositol-mediated signaling, positive regulation of T cell proliferation, positive regulation of alpha-beta T cell proliferation, positive regulation of inflammatory response to antigenic stimulus, positive regulation of interleukin-2 biosynthetic process, positive regulation of isotype switching to IgG isotypes, positive regulation of mitosis, positive regulation of transcription from RNA polymerase II promoter, positive regulation of translation, positive regulation of viral genome replication, regulation of defense response to virus by virus, regulatory T cell differentiation, viral reproduction cytosol, external side of plasma membrane, integral to plasma membrane, membrane, plasma membrane SH3/SH2 adaptor activity, coreceptor activity, identical protein binding, protease binding, protein binding Human UniProtKB:P10747 CD2AP HPA UniProtKB {GO:0005515=PMID:21988832, GO:0017124=PMID:10339567, GO:0005886=GO_REF:0000052, GO:0005730=GO_REF:0000052, GO:0015629=PMID:10339567, GO:0001726=PMID:10339567, GO:0006930=PMID:10339567, GO:0007165=PMID:10339567, GO:0007067=GO_REF:0000037, GO:0005737=GO_REF:0000052, GO:0031941=PMID:10339567, GO:0006461=PMID:10339567, GO:0005200=PMID:10339567, GO:0051301=GO_REF:0000037} Q9Y5K6 CD2-associated protein protein 20080205 {GO:0005515=IPI, GO:0017124=IPI, GO:0005886=IDA, GO:0005730=IDA, GO:0015629=TAS, GO:0001726=IDA, GO:0006930=TAS, GO:0007165=NAS, GO:0007067=IEA, GO:0005737=IDA, GO:0031941=IDA, GO:0006461=TAS, GO:0005200=TAS, GO:0051301=IEA} cell division, mitosis, protein complex assembly, signal transduction, substrate-dependent cell migration, cell extension actin cytoskeleton, cytoplasm, filamentous actin, nucleolus, plasma membrane, ruffle SH3 domain binding, protein binding, structural constituent of cytoskeleton Human CD2BP2 BHF-UCL UniProtKB {GO:0008380=Reactome:REACT_1735, GO:0000244=PMID:15840814, GO:0005515=PMID:15840814, GO:0010467=Reactome:REACT_71, GO:0005634=PMID:15840814, GO:0005737=GO_REF:0000039, GO:0016607=PMID:15840814, GO:0000398=Reactome:REACT_467, GO:0010923=PMID:19389623, GO:0043021=PMID:15840814, GO:0005654=PMID:15840814, GO:0005682=PMID:15840814, GO:0046540=PMID:15840814} O95400 CD2 antigen cytoplasmic tail-binding protein 2 protein 20091118 {GO:0008380=TAS, GO:0000244=NAS, GO:0005515=IPI, GO:0010467=TAS, GO:0005634=IDA, GO:0005737=IEA, GO:0016607=IDA, GO:0000398=TAS, GO:0010923=IDA, GO:0043021=IDA, GO:0005654=IDA, GO:0005682=IDA, GO:0046540=IDA} RNA splicing, assembly of spliceosomal tri-snRNP, gene expression, mRNA splicing, via spliceosome, negative regulation of phosphatase activity U4/U6 x U5 tri-snRNP complex, U5 snRNP, cytoplasm, nuclear speck, nucleoplasm, nucleus protein binding, ribonucleoprotein complex binding Human UniProtKB:P83876 CD300A UniProtKB UniProtKB {GO:0005886=GO_REF:0000039, GO:0016021=GO_REF:0000037, GO:0007155=GO_REF:0000037} Q9UGN4 CMRF35-like molecule 8 protein 20130413 {GO:0005886=IEA, GO:0016021=IEA, GO:0007155=IEA} cell adhesion integral to membrane, plasma membrane Human UniProtKB-SubCell:SL-0039 CD300C PINC UniProtKB {GO:0006968=PMID:1349532, GO:0005887=PMID:1349532, GO:0004888=PMID:1349532} Q08708 CMRF35-like molecule 6 protein 20030904 {GO:0006968=TAS, GO:0005887=TAS, GO:0004888=TAS} cellular defense response integral to plasma membrane transmembrane signaling receptor activity Human CD300E Reactome UniProtKB {GO:0005886=Reactome:REACT_147704, GO:0045087=Reactome:REACT_6802, GO:0016021=GO_REF:0000037} Q496F6 CMRF35-like molecule 2 protein 20120221 {GO:0005886=TAS, GO:0045087=TAS, GO:0016021=IEA} innate immune response integral to membrane, plasma membrane Human CD300LB Reactome UniProtKB {GO:0005886=Reactome:REACT_147706, GO:0045087=Reactome:REACT_6802, GO:0016021=GO_REF:0000037} A8K4G0 CMRF35-like molecule 7 protein 20120806 {GO:0005886=TAS, GO:0045087=TAS, GO:0016021=IEA} innate immune response integral to membrane, plasma membrane Human CD300LF UniProtKB UniProtKB {GO:0005886=GO_REF:0000039, GO:0016021=GO_REF:0000037} Q8TDQ1 CMRF35-like molecule 1 protein 20130413 {GO:0005886=IEA, GO:0016021=IEA} integral to membrane, plasma membrane Human UniProtKB-SubCell:SL-0039 CD302 MGI UniProtKB {GO:0006909=PMID:17947679, GO:0005902=GO_REF:0000039, GO:0030246=GO_REF:0000002, GO:0030175=PMID:17947679, GO:0016021=GO_REF:0000037, GO:0005938=PMID:17947679} Q8IX05 CD302 antigen protein 20120402 {GO:0006909=IDA, GO:0005902=IEA, GO:0030246=IEA, GO:0030175=IDA, GO:0016021=IEA, GO:0005938=IDA} phagocytosis cell cortex, filopodium, integral to membrane, microvillus carbohydrate binding Human CD320 LIFEdb UniProtKB {GO:0003674=GO_REF:0000015, GO:0031419=PMID:18779389, GO:0005886=PMID:18779389, GO:0005783=GO_REF:0000054, GO:0016021=GO_REF:0000037, GO:0001558=PMID:10727470, GO:0008083=GO_REF:0000037} Q9NPF0 CD320 antigen protein 20100607 {GO:0003674=ND, GO:0031419=IDA, GO:0005886=IDA, GO:0005783=IDA, GO:0016021=IEA, GO:0001558=NAS, GO:0008083=IEA} regulation of cell growth endoplasmic reticulum, integral to membrane, plasma membrane cobalamin binding, growth factor activity, molecular_function Human CD33 MGI UniProtKB {GO:0007165=PMID:10611343, GO:0008285=PMID:10611343, GO:0005886=PMID:3139766, GO:0005887=PMID:3139766, GO:0007267=PMID:10611343, GO:0004872=PMID:10611343, GO:0007155=GO_REF:0000037, GO:0009897=PMID:20660734} P20138 Myeloid cell surface antigen CD33 protein 20110510 {GO:0007165=TAS, GO:0008285=TAS, GO:0005886=TAS, GO:0005887=TAS, GO:0007267=TAS, GO:0004872=TAS, GO:0007155=IEA, GO:0009897=IDA} cell adhesion, cell-cell signaling, negative regulation of cell proliferation, signal transduction external side of plasma membrane, integral to plasma membrane, plasma membrane receptor activity Human CD34 InterPro UniProtKB {GO:0071657=PMID:9815891, GO:0005886=Reactome:REACT_11230, GO:0042482=PMID:12939361, GO:0008283=GO_REF:0000024, GO:0050900=GO_REF:0000024, GO:0005764=GO_REF:0000024, GO:0016337=PMID:15249540, GO:0016324=GO_REF:0000024, GO:0009925=GO_REF:0000024, GO:0048870=PMID:17261663, GO:0072254=PMID:1868864, GO:1900041=PMID:9815891, GO:1900168=PMID:17505307, GO:0007155=GO_REF:0000002, GO:0030097=PMID:15969628, GO:0072089=PMID:17261663, GO:0043199=GO_REF:0000019, GO:0003158=PMID:17261663, GO:0038001=PMID:21835908, GO:0007165=PMID:17261663, GO:0071425=PMID:21873977, GO:0036053=GO_REF:0000024, GO:0016020=GO_REF:0000002, GO:0005887=PMID:9042286, GO:0003094=PMID:20354148, GO:0050776=Reactome:REACT_11152, GO:0010629=PMID:15969628, GO:0071971=PMID:21835908, GO:0030246=PMID:15249540, GO:0035759=GO_REF:0000024, GO:0009897=PMID:15249540, GO:0008134=PMID:21873977} Q5JTA5 Hematopoietic progenitor cell antigen CD34 protein 20130413 {GO:0071657=IDA, GO:0005886=TAS, GO:0042482=IDA, GO:0008283=ISS, GO:0050900=ISS, GO:0005764=ISS, GO:0016337=IDA, GO:0016324=ISS, GO:0009925=ISS, GO:0048870=IEP, GO:0072254=IEP, GO:1900041=IMP, GO:1900168=IDA, GO:0007155=IEA, GO:0030097=IMP, GO:0072089=IEP, GO:0043199=IEA, GO:0003158=IEP, GO:0038001=IDA, GO:0007165=IEP, GO:0071425=IMP, GO:0036053=ISS, GO:0016020=IEA, GO:0005887=TAS, GO:0003094=IEP, GO:0050776=TAS, GO:0010629=IMP, GO:0071971=IDA, GO:0030246=IDA, GO:0035759=ISS, GO:0009897=IC, GO:0008134=IPI} cell adhesion, cell motility, cell proliferation, cell-cell adhesion, endothelium development, extracellular vesicular exosome assembly, glomerular filtration, hematopoietic stem cell proliferation, hemopoiesis, leukocyte migration, mesangial cell-matrix adhesion, metanephric glomerular mesangial cell differentiation, negative regulation of gene expression, negative regulation of interleukin-2 secretion, paracrine signaling, positive regulation of glial cell line-derived neurotrophic factor secretion, positive regulation of granulocyte colony-stimulating factor production, positive regulation of odontogenesis, regulation of immune response, signal transduction, stem cell proliferation apical plasma membrane, basal plasma membrane, external side of plasma membrane, glomerular endothelium fenestra, integral to plasma membrane, lysosome, membrane, plasma membrane carbohydrate binding, sulfate binding, transcription factor binding Human InterPro:IPR008083 CD36 BHF-UCL UniProtKB {GO:0032755=GO_REF:0000019, GO:0002474=Reactome:REACT_75820, GO:0035634=GO_REF:0000019, GO:0019915=PMID:10772654, GO:0050830=GO_REF:0000019, GO:0050731=GO_REF:0000019, GO:0030301=PMID:12376530, GO:0042992=GO_REF:0000019, GO:0060100=GO_REF:0000019, GO:0005041=PMID:10772654, GO:0015911=PMID:17416590, GO:0042953=PMID:10772654, GO:0002755=Reactome:REACT_6788, GO:0043123=GO_REF:0000019, GO:0044130=GO_REF:0000019, GO:0044255=Reactome:REACT_22279, GO:0038124=Reactome:REACT_8006, GO:0005794=GO_REF:0000019, GO:0009986=GO_REF:0000024, GO:0038123=Reactome:REACT_8005, GO:0032760=GO_REF:0000019, GO:0010744=PMID:10772654, GO:0034134=Reactome:REACT_7980, GO:0030169=PMID:10772654, GO:0030168=Reactome:REACT_798, GO:0043277=GO_REF:0000019, GO:0000122=GO_REF:0000019, GO:0002224=Reactome:REACT_6966, GO:0055096=GO_REF:0000019, GO:0005887=PMID:9568716, GO:0045087=Reactome:REACT_6802, GO:0045121=GO_REF:0000019, GO:2000379=GO_REF:0000019, GO:0001954=PMID:17416590, GO:0009897=GO_REF:0000019, GO:0070053=GO_REF:0000024, GO:0008035=GO_REF:0000019, GO:0006629=PMID:7518447, GO:0034142=Reactome:REACT_6894, GO:0007263=PMID:17416590, GO:0005886=Reactome:REACT_150418, GO:0070892=GO_REF:0000019, GO:0071447=GO_REF:0000019, GO:0032735=GO_REF:0000019, GO:0019934=PMID:17416590, GO:0044281=Reactome:REACT_111217, GO:2000334=GO_REF:0000019, GO:2000121=GO_REF:0000019, GO:0008289=PMID:10772654, GO:0034383=PMID:10772654, GO:0034381=PMID:12376530, GO:0031092=Reactome:REACT_21394, GO:0007155=GO_REF:0000037, GO:0044539=PMID:22022213, GO:0050431=GO_REF:0000024, GO:0071813=PMID:9568716, GO:0042590=Reactome:REACT_111119, GO:0010886=GO_REF:0000019, GO:0006910=GO_REF:0000019, GO:0045335=Reactome:REACT_111116, GO:0051636=GO_REF:0000019, GO:0071221=GO_REF:0000019, GO:0071223=GO_REF:0000019, GO:0071222=GO_REF:0000019, GO:0016020=PMID:2468669, GO:0007596=Reactome:REACT_604, GO:0030194=GO_REF:0000019, GO:0002576=Reactome:REACT_318, GO:0051637=GO_REF:0000019, GO:0060907=GO_REF:0000019, GO:0002479=Reactome:REACT_111174, GO:0016021=GO_REF:0000038, GO:0043410=GO_REF:0000019, GO:0007166=GO_REF:0000019} P16671 Platelet glycoprotein 4 protein 20081021 {GO:0032755=IEA, GO:0002474=TAS, GO:0035634=IEA, GO:0019915=IMP, GO:0050830=IEA, GO:0050731=IEA, GO:0030301=ISS, GO:0042992=IEA, GO:0060100=IEA, GO:0005041=IMP, GO:0015911=IDA, GO:0042953=IMP, GO:0002755=TAS, GO:0043123=IEA, GO:0044130=IEA, GO:0044255=TAS, GO:0038124=TAS, GO:0005794=IEA, GO:0009986=ISS, GO:0038123=TAS, GO:0032760=IEA, GO:0010744=IMP, GO:0034134=TAS, GO:0030169=IDA, GO:0030168=TAS, GO:0043277=IEA, GO:0000122=IEA, GO:0002224=TAS, GO:0055096=IEA, GO:0005887=TAS, GO:0045087=TAS, GO:0045121=IEA, GO:2000379=IEA, GO:0001954=IDA, GO:0009897=IEA, GO:0070053=ISS, GO:0008035=IEA, GO:0006629=NAS, GO:0034142=TAS, GO:0007263=IDA, GO:0005886=TAS, GO:0070892=IEA, GO:0071447=IEA, GO:0032735=IEA, GO:0019934=IDA, GO:0044281=TAS, GO:2000334=IEA, GO:2000121=IEA, GO:0008289=IDA, GO:0034383=IMP, GO:0034381=ISS, GO:0031092=TAS, GO:0007155=IEA, GO:0044539=IDA, GO:0050431=ISS, GO:0071813=IDA, GO:0042590=TAS, GO:0010886=IEA, GO:0006910=IEA, GO:0045335=TAS, GO:0051636=IEA, GO:0071221=IEA, GO:0071223=IEA, GO:0071222=IEA, GO:0016020=TAS, GO:0007596=TAS, GO:0030194=IEA, GO:0002576=TAS, GO:0051637=IEA, GO:0060907=IEA, GO:0002479=TAS, GO:0016021=IEA, GO:0043410=IEA, GO:0007166=IEA} MyD88-dependent toll-like receptor signaling pathway, antigen processing and presentation of exogenous peptide antigen via MHC class I, antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent, antigen processing and presentation of peptide antigen via MHC class I, apoptotic cell clearance, blood coagulation, cGMP-mediated signaling, cell adhesion, cell surface receptor signaling pathway, cellular lipid metabolic process, cellular response to bacterial lipopeptide, cellular response to hydroperoxide, cellular response to lipopolysaccharide, cellular response to lipoteichoic acid, cholesterol transport, defense response to Gram-positive bacterium, innate immune response, lipid metabolic process, lipid storage, lipoprotein transport, long-chain fatty acid import, low-density lipoprotein particle clearance, low-density lipoprotein particle mediated signaling, negative regulation of growth of symbiont in host, negative regulation of transcription factor import into nucleus, negative regulation of transcription from RNA polymerase II promoter, nitric oxide mediated signal transduction, phagocytosis, recognition, plasma lipoprotein particle clearance, plasma membrane long-chain fatty acid transport, platelet activation, platelet degranulation, positive regulation of I-kappaB kinase/NF-kappaB cascade, positive regulation of MAPK cascade, positive regulation of blood coagulation, positive regulation of blood microparticle formation, positive regulation of cell-matrix adhesion, positive regulation of cholesterol storage, positive regulation of interleukin-12 production, positive regulation of interleukin-6 production, positive regulation of macrophage cytokine production, positive regulation of macrophage derived foam cell differentiation, positive regulation of peptidyl-tyrosine phosphorylation, positive regulation of phagocytosis, engulfment, positive regulation of reactive oxygen species metabolic process, positive regulation of tumor necrosis factor production, regulation of removal of superoxide radicals, response to stilbenoid, small molecule metabolic process, toll-like receptor 2 signaling pathway, toll-like receptor 4 signaling pathway, toll-like receptor TLR1:TLR2 signaling pathway, toll-like receptor TLR6:TLR2 signaling pathway, toll-like receptor signaling pathway Golgi apparatus, cell surface, external side of plasma membrane, integral to membrane, integral to plasma membrane, membrane, membrane raft, phagocytic vesicle, plasma membrane, platelet alpha granule membrane Gram-negative bacterial cell surface binding, Gram-positive bacterial cell surface binding, high-density lipoprotein particle binding, lipid binding, lipoprotein particle binding, lipoteichoic acid receptor activity, low-density lipoprotein particle binding, low-density lipoprotein receptor activity, thrombospondin receptor activity, transforming growth factor beta binding Human UniProtKB:Q07969 CD38 PINC UniProtKB {GO:0050853=PMID:17875758, GO:0005886=GO_REF:0000019, GO:0030307=GO_REF:0000019, GO:0030890=PMID:17875758, GO:0005634=GO_REF:0000019, GO:0060292=GO_REF:0000019, GO:0007204=GO_REF:0000019, GO:0045779=GO_REF:0000019, GO:0045907=GO_REF:0000019, GO:0032024=GO_REF:0000019, GO:0032526=GO_REF:0000019, GO:0032355=GO_REF:0000019, GO:0033194=GO_REF:0000019, GO:0070555=GO_REF:0000019, GO:0001666=GO_REF:0000019, GO:0007565=GO_REF:0000019, GO:0043066=PMID:17875758, GO:0016849=GO_REF:0000019, GO:0009986=GO_REF:0000019, GO:0042493=PMID:17875758, GO:0097190=PMID:10777496, GO:0007165=PMID:8253715, GO:0003953=GO_REF:0000003, GO:0016020=PMID:8253715, GO:0032570=GO_REF:0000019, GO:0016021=GO_REF:0000037, GO:0045893=PMID:17875758, GO:0045892=PMID:17875758} P28907 ADP-ribosyl cyclase 1 protein 20030904 {GO:0050853=IMP, GO:0005886=IEA, GO:0030307=IEA, GO:0030890=IMP, GO:0005634=IEA, GO:0060292=IEA, GO:0007204=IEA, GO:0045779=IEA, GO:0045907=IEA, GO:0032024=IEA, GO:0032526=IEA, GO:0032355=IEA, GO:0033194=IEA, GO:0070555=IEA, GO:0001666=IEA, GO:0007565=IEA, GO:0043066=IMP, GO:0016849=IEA, GO:0009986=IEA, GO:0042493=IMP, GO:0097190=TAS, GO:0007165=NAS, GO:0003953=IEA, GO:0016020=TAS, GO:0032570=IEA, GO:0016021=IEA, GO:0045893=IMP, GO:0045892=IMP} B cell receptor signaling pathway, apoptotic signaling pathway, elevation of cytosolic calcium ion concentration, female pregnancy, long term synaptic depression, negative regulation of apoptotic process, negative regulation of bone resorption, negative regulation of transcription, DNA-dependent, positive regulation of B cell proliferation, positive regulation of cell growth, positive regulation of insulin secretion, positive regulation of transcription, DNA-dependent, positive regulation of vasoconstriction, response to drug, response to estradiol stimulus, response to hydroperoxide, response to hypoxia, response to interleukin-1, response to progesterone stimulus, response to retinoic acid, signal transduction cell surface, integral to membrane, membrane, nucleus, plasma membrane NAD+ nucleosidase activity, phosphorus-oxygen lyase activity Human CD3D Reactome UniProtKB {GO:0050852=Reactome:REACT_12526, GO:0046982=PMID:9485181, GO:0005886=Reactome:REACT_19146, GO:0031295=Reactome:REACT_19344, GO:0003713=PMID:2017177, GO:0045059=GO_REF:0000024, GO:0042105=GO_REF:0000019, GO:0005737=PMID:1831653, GO:0016020=GO_REF:0000002, GO:0030217=PMID:2017177, GO:0042101=PMID:8176201, GO:0045944=PMID:2017177, GO:0050776=Reactome:REACT_11152, GO:0016021=GO_REF:0000037, GO:0007166=PMID:9485181, GO:0004888=PMID:9485181} P04234 T-cell surface glycoprotein CD3 delta chain protein 20070516 {GO:0050852=TAS, GO:0046982=IPI, GO:0005886=TAS, GO:0031295=TAS, GO:0003713=IDA, GO:0045059=ISS, GO:0042105=IEA, GO:0005737=NAS, GO:0016020=IEA, GO:0030217=IDA, GO:0042101=IDA, GO:0045944=IDA, GO:0050776=TAS, GO:0016021=IEA, GO:0007166=IC, GO:0004888=IC} T cell costimulation, T cell differentiation, T cell receptor signaling pathway, cell surface receptor signaling pathway, positive regulation of transcription from RNA polymerase II promoter, positive thymic T cell selection, regulation of immune response T cell receptor complex, alpha-beta T cell receptor complex, cytoplasm, integral to membrane, membrane, plasma membrane protein heterodimerization activity, transcription coactivator activity, transmembrane signaling receptor activity Human CD3E Reactome UniProtKB {GO:0050852=Reactome:REACT_12526, GO:0032753=GO_REF:0000019, GO:0017124=PMID:12110186, GO:0005886=Reactome:REACT_19146, GO:0031295=Reactome:REACT_19344, GO:0050731=GO_REF:0000019, GO:0030159=PMID:9886373, GO:0045879=GO_REF:0000019, GO:0050850=GO_REF:0000019, GO:0042105=GO_REF:0000019, GO:0042608=PMID:11186279, GO:0007172=PMID:8490660, GO:0042101=PMID:8176201, GO:0042102=PMID:12110186, GO:0046641=GO_REF:0000019, GO:0032729=GO_REF:0000019, GO:0001772=GO_REF:0000019, GO:0019901=PMID:12110186, GO:0046982=PMID:9485181, GO:0007584=GO_REF:0000019, GO:0042981=PMID:12567487, GO:0045086=GO_REF:0000019, GO:0042110=PMID:12110186, GO:0006461=PMID:9886373, GO:0007186=PMID:8530500, GO:0016020=GO_REF:0000002, GO:0005887=PMID:9485181, GO:0050776=Reactome:REACT_11152, GO:0002669=GO_REF:0000019, GO:0045060=GO_REF:0000019, GO:0005057=PMID:1370449, GO:0007169=PMID:8530500, GO:0009897=PMID:17213291, GO:0007166=PMID:12110186, GO:0004888=PMID:9485181} P07766 T-cell surface glycoprotein CD3 epsilon chain protein 20070515 {GO:0050852=TAS, GO:0032753=IEA, GO:0017124=IPI, GO:0005886=TAS, GO:0031295=TAS, GO:0050731=IEA, GO:0030159=NAS, GO:0045879=IEA, GO:0050850=IEA, GO:0042105=IEA, GO:0042608=NAS, GO:0007172=TAS, GO:0042101=IDA, GO:0042102=IMP, GO:0046641=IEA, GO:0032729=IEA, GO:0001772=IEA, GO:0019901=NAS, GO:0046982=IPI, GO:0007584=IEA, GO:0042981=NAS, GO:0045086=IEA, GO:0042110=NAS, GO:0006461=NAS, GO:0007186=TAS, GO:0016020=IEA, GO:0005887=NAS, GO:0050776=TAS, GO:0002669=IEA, GO:0045060=IEA, GO:0005057=TAS, GO:0007169=TAS, GO:0009897=IDA, GO:0007166=NAS, GO:0004888=NAS} G-protein coupled receptor signaling pathway, T cell activation, T cell costimulation, T cell receptor signaling pathway, cell surface receptor signaling pathway, negative regulation of smoothened signaling pathway, negative thymic T cell selection, positive regulation of T cell anergy, positive regulation of T cell proliferation, positive regulation of alpha-beta T cell proliferation, positive regulation of calcium-mediated signaling, positive regulation of interferon-gamma production, positive regulation of interleukin-2 biosynthetic process, positive regulation of interleukin-4 production, positive regulation of peptidyl-tyrosine phosphorylation, protein complex assembly, regulation of apoptotic process, regulation of immune response, response to nutrient, signal complex assembly, transmembrane receptor protein tyrosine kinase signaling pathway T cell receptor complex, alpha-beta T cell receptor complex, external side of plasma membrane, immunological synapse, integral to plasma membrane, membrane, plasma membrane SH3 domain binding, T cell receptor binding, protein heterodimerization activity, protein kinase binding, receptor signaling complex scaffold activity, receptor signaling protein activity, transmembrane signaling receptor activity Human CD3EAP HPA UniProtKB {GO:0005739=GO_REF:0000052, GO:0005737=GO_REF:0000052, GO:0005694=GO_REF:0000039, GO:0005736=GO_REF:0000019, GO:0003899=GO_REF:0000037, GO:0009303=GO_REF:0000019, GO:0005730=GO_REF:0000052, GO:0000120=PMID:9426281, GO:0005634=GO_REF:0000052, GO:0007169=PMID:10373416} O15446 DNA-directed RNA polymerase I subunit RPA34 protein 20111111 {GO:0005739=IDA, GO:0005737=IDA, GO:0005694=IEA, GO:0005736=IEA, GO:0003899=IEA, GO:0009303=IEA, GO:0005730=IDA, GO:0000120=TAS, GO:0005634=IDA, GO:0007169=TAS} rRNA transcription, transmembrane receptor protein tyrosine kinase signaling pathway DNA-directed RNA polymerase I complex, RNA polymerase I transcription factor complex, chromosome, cytoplasm, mitochondrion, nucleolus, nucleus DNA-directed RNA polymerase activity Human CD3G Reactome UniProtKB {GO:0050852=Reactome:REACT_12526, GO:0005886=Reactome:REACT_160317, GO:0046982=PMID:9485181, GO:0031295=Reactome:REACT_19344, GO:0030159=PMID:12794121, GO:0042981=PMID:12407027, GO:0015031=PMID:12794121, GO:0042105=GO_REF:0000019, GO:0042110=PMID:12407027, GO:0042608=PMID:11186279, GO:0006461=PMID:12794121, GO:0007163=PMID:12407027, GO:0016020=GO_REF:0000002, GO:0005887=PMID:9485181, GO:0045087=Reactome:REACT_6802, GO:0042101=PMID:9485181, GO:0050776=Reactome:REACT_11152, GO:0038096=Reactome:REACT_160123, GO:0007166=PMID:12407027, GO:0004888=PMID:12794121} P09693 T-cell surface glycoprotein CD3 gamma chain protein 20110908 {GO:0050852=TAS, GO:0005886=TAS, GO:0046982=IPI, GO:0031295=TAS, GO:0030159=NAS, GO:0042981=IMP, GO:0015031=IMP, GO:0042105=IEA, GO:0042110=NAS, GO:0042608=NAS, GO:0006461=NAS, GO:0007163=IMP, GO:0016020=IEA, GO:0005887=NAS, GO:0045087=TAS, GO:0042101=NAS, GO:0050776=TAS, GO:0038096=TAS, GO:0007166=IMP, GO:0004888=IMP} Fc-gamma receptor signaling pathway involved in phagocytosis, T cell activation, T cell costimulation, T cell receptor signaling pathway, cell surface receptor signaling pathway, establishment or maintenance of cell polarity, innate immune response, protein complex assembly, protein transport, regulation of apoptotic process, regulation of immune response T cell receptor complex, alpha-beta T cell receptor complex, integral to plasma membrane, membrane, plasma membrane T cell receptor binding, protein heterodimerization activity, receptor signaling complex scaffold activity, transmembrane signaling receptor activity Human CD4 Reactome UniProtKB {GO:0005515=PMID:19333378, GO:0050852=Reactome:REACT_12526, GO:0022415=Reactome:REACT_6266, GO:0042289=PMID:8512039, GO:0005886=Reactome:REACT_116084, GO:0030260=Reactome:REACT_6903, GO:0031295=Reactome:REACT_19344, GO:0050731=GO_REF:0000019, GO:0001816=GO_REF:0000019, GO:0042803=PMID:12444132, GO:0050850=GO_REF:0000019, GO:0006955=PMID:8512039, GO:0001948=PMID:10922058, GO:0042101=PMID:8512039, GO:0045860=PMID:2118992, GO:0016032=Reactome:REACT_6256, GO:0004872=PMID:10413516, GO:0032507=PMID:15128768, GO:0007155=GO_REF:0000002, GO:0050863=PMID:1533274, GO:0019901=PMID:7486703, GO:0015026=PMID:8512039, GO:0045234=PMID:15128768, GO:0050690=Reactome:REACT_11166, GO:0045058=PMID:9551897, GO:0006948=PMID:9166430, GO:0050829=GO_REF:0000019, GO:0045086=PMID:1901411, GO:0007165=PMID:9558100, GO:0042110=GO_REF:0000019, GO:0030217=PMID:1533274, GO:0045087=Reactome:REACT_6802, GO:0050870=GO_REF:0000019, GO:0005789=Reactome:REACT_9071, GO:0005788=GO_REF:0000019, GO:0008270=PMID:9668045, GO:0045121=GO_REF:0000019, GO:0016021=GO_REF:0000037, GO:0019899=PMID:19333378, GO:0007169=PMID:8512039, GO:0005769=Reactome:REACT_11227, GO:0009897=PMID:17213291, GO:0007166=PMID:9780207, GO:0007167=PMID:10358157, GO:0004888=PMID:10358157, GO:0005201=PMID:12444132} P01730 T-cell surface glycoprotein CD4 protein 20070516 {GO:0005515=IPI, GO:0050852=TAS, GO:0022415=TAS, GO:0042289=NAS, GO:0005886=TAS, GO:0030260=TAS, GO:0031295=TAS, GO:0050731=IEA, GO:0001816=IEA, GO:0042803=IDA, GO:0050850=IEA, GO:0006955=NAS, GO:0001948=IPI, GO:0042101=NAS, GO:0045860=IDA, GO:0016032=TAS, GO:0004872=TAS, GO:0032507=IDA, GO:0007155=IEA, GO:0050863=IDA, GO:0019901=IPI, GO:0015026=NAS, GO:0045234=IDA, GO:0050690=TAS, GO:0045058=IDA, GO:0006948=IDA, GO:0050829=IEA, GO:0045086=NAS, GO:0007165=TAS, GO:0042110=IEA, GO:0030217=IDA, GO:0045087=TAS, GO:0050870=IEA, GO:0005789=TAS, GO:0005788=IEA, GO:0008270=IDA, GO:0045121=IEA, GO:0016021=IEA, GO:0019899=IPI, GO:0007169=NAS, GO:0005769=TAS, GO:0009897=IDA, GO:0007166=TAS, GO:0007167=TAS, GO:0004888=TAS, GO:0005201=NAS} T cell activation, T cell costimulation, T cell differentiation, T cell receptor signaling pathway, T cell selection, cell adhesion, cell surface receptor signaling pathway, cytokine production, defense response to Gram-negative bacterium, entry into host cell, enzyme linked receptor protein signaling pathway, immune response, induction by virus of host cell-cell fusion, innate immune response, maintenance of protein location in cell, positive regulation of T cell activation, positive regulation of calcium-mediated signaling, positive regulation of interleukin-2 biosynthetic process, positive regulation of peptidyl-tyrosine phosphorylation, positive regulation of protein kinase activity, protein palmitoleylation, regulation of T cell activation, regulation of defense response to virus by virus, signal transduction, transmembrane receptor protein tyrosine kinase signaling pathway, viral reproduction, viral reproductive process T cell receptor complex, early endosome, endoplasmic reticulum lumen, endoplasmic reticulum membrane, external side of plasma membrane, integral to membrane, membrane raft, plasma membrane MHC class II protein binding, coreceptor activity, enzyme binding, extracellular matrix structural constituent, glycoprotein binding, protein binding, protein homodimerization activity, protein kinase binding, receptor activity, transmembrane signaling receptor activity, zinc ion binding Human CD40 BHF-UCL UniProtKB {GO:0005515=PMID:20676093, GO:0035631=GO_REF:0000024, GO:0005886=GO_REF:0000024, GO:0030890=GO_REF:0000019, GO:0032735=GO_REF:0000019, GO:0032855=PMID:21410936, GO:0043231=GO_REF:0000019, GO:0051607=GO_REF:0000019, GO:0006954=PMID:2475341, GO:0051092=PMID:21410936, GO:0090037=PMID:21410936, GO:0043406=PMID:21410936, GO:0042100=PMID:8605945, GO:0045944=PMID:21410936, GO:0043089=PMID:21410936, GO:0004872=PMID:10092834, GO:0004871=PMID:9671306, GO:0043123=PMID:12761501, GO:0031625=PMID:11279055, GO:0006874=PMID:21410936, GO:0042511=PMID:21410936, GO:0030168=PMID:9468137, GO:0005576=GO_REF:0000039, GO:0051023=GO_REF:0000019, GO:0002768=GO_REF:0000019, GO:0006461=PMID:10748139, GO:0005887=PMID:10748139, GO:0050776=Reactome:REACT_11152, GO:0001934=PMID:21410936, GO:0071260=PMID:19593445, GO:0019899=PMID:12223522, GO:2000353=PMID:12885753, GO:0048304=GO_REF:0000019, GO:0009897=GO_REF:0000019} P25942 Tumor necrosis factor receptor superfamily member 5 protein 20110223 {GO:0005515=IPI, GO:0035631=ISS, GO:0005886=ISS, GO:0030890=IEA, GO:0032735=IEA, GO:0032855=IMP, GO:0043231=IEA, GO:0051607=IEA, GO:0006954=TAS, GO:0051092=IMP, GO:0090037=IMP, GO:0043406=IMP, GO:0042100=NAS, GO:0045944=IMP, GO:0043089=IMP, GO:0004872=TAS, GO:0004871=TAS, GO:0043123=IEP, GO:0031625=IPI, GO:0006874=IMP, GO:0042511=IMP, GO:0030168=NAS, GO:0005576=IEA, GO:0051023=IEA, GO:0002768=IEA, GO:0006461=TAS, GO:0005887=TAS, GO:0050776=TAS, GO:0001934=IMP, GO:0071260=IEP, GO:0019899=IPI, GO:2000353=IDA, GO:0048304=IEA, GO:0009897=IEA} B cell proliferation, cellular calcium ion homeostasis, cellular response to mechanical stimulus, defense response to virus, immune response-regulating cell surface receptor signaling pathway, inflammatory response, platelet activation, positive regulation of B cell proliferation, positive regulation of Cdc42 GTPase activity, positive regulation of I-kappaB kinase/NF-kappaB cascade, positive regulation of MAP kinase activity, positive regulation of NF-kappaB transcription factor activity, positive regulation of Rac GTPase activity, positive regulation of endothelial cell apoptotic process, positive regulation of interleukin-12 production, positive regulation of isotype switching to IgG isotypes, positive regulation of protein kinase C signaling cascade, positive regulation of protein phosphorylation, positive regulation of transcription from RNA polymerase II promoter, positive regulation of tyrosine phosphorylation of Stat1 protein, protein complex assembly, regulation of immune response, regulation of immunoglobulin secretion CD40 receptor complex, external side of plasma membrane, extracellular region, integral to plasma membrane, intracellular membrane-bounded organelle, plasma membrane enzyme binding, protein binding, receptor activity, signal transducer activity, ubiquitin protein ligase binding Human CD40LG BHF-UCL UniProtKB {GO:0005164=GO_REF:0000002, GO:0043066=PMID:12697681, GO:0005886=Reactome:REACT_11241, GO:0045190=GO_REF:0000024, GO:0030168=PMID:9468137, GO:0032735=PMID:9922218, GO:0005125=GO_REF:0000037, GO:0005615=GO_REF:0000037, GO:0051023=GO_REF:0000019, GO:0006954=PMID:9468137, GO:0005887=PMID:7678552, GO:0042100=PMID:8605945, GO:0050776=Reactome:REACT_11152, GO:0030183=GO_REF:0000019, GO:0007159=PMID:9468137, GO:0016021=PMID:9468137, GO:2000353=PMID:12885753, GO:0009897=GO_REF:0000019, GO:0048305=GO_REF:0000019, GO:0005174=PMID:9468137} P29965 CD40 ligand protein 20110223 {GO:0005164=IEA, GO:0043066=IDA, GO:0005886=TAS, GO:0045190=ISS, GO:0030168=IDA, GO:0032735=IDA, GO:0005125=IEA, GO:0005615=IEA, GO:0051023=IEA, GO:0006954=IDA, GO:0005887=TAS, GO:0042100=IDA, GO:0050776=TAS, GO:0030183=IEA, GO:0007159=NAS, GO:0016021=NAS, GO:2000353=IDA, GO:0009897=IEA, GO:0048305=IEA, GO:0005174=IPI} B cell differentiation, B cell proliferation, immunoglobulin secretion, inflammatory response, isotype switching, leukocyte cell-cell adhesion, negative regulation of apoptotic process, platelet activation, positive regulation of endothelial cell apoptotic process, positive regulation of interleukin-12 production, regulation of immune response, regulation of immunoglobulin secretion external side of plasma membrane, extracellular space, integral to membrane, integral to plasma membrane, plasma membrane CD40 receptor binding, cytokine activity, tumor necrosis factor receptor binding Human CD44 InterPro UniProtKB {GO:0005515=PMID:11207560, GO:0001658=GO_REF:0000019, GO:0005886=Reactome:REACT_120971, GO:0051216=PMID:11944887, GO:0019221=Reactome:REACT_25229, GO:0005518=PMID:2471973, GO:0050731=PMID:17045821, GO:0044281=Reactome:REACT_111217, GO:0016323=GO_REF:0000019, GO:0033138=PMID:17045821, GO:0005737=GO_REF:0000052, GO:0016337=PMID:1922057, GO:0005540=GO_REF:0000002, GO:0034116=PMID:15100360, GO:0070374=PMID:17045821, GO:0043154=PMID:19047049, GO:0016055=GO_REF:0000019, GO:0007155=GO_REF:0000002, GO:1900625=PMID:20522558, GO:0030203=Reactome:REACT_121315, GO:0060333=Reactome:REACT_25078, GO:0043066=PMID:17045821, GO:0005794=GO_REF:0000052, GO:0009986=PMID:16809613, GO:0005975=Reactome:REACT_474, GO:0002246=GO_REF:0000019, GO:0044344=PMID:19577615, GO:0060442=GO_REF:0000019, GO:0010628=GO_REF:0000019, GO:0016020=GO_REF:0000002, GO:0007160=PMID:1922057, GO:0005887=PMID:1991450, GO:0070487=PMID:15100360, GO:0043518=PMID:17045821, GO:0030212=Reactome:REACT_121083, GO:0004415=PMID:17170110, GO:0030214=Reactome:REACT_120996, GO:0009897=GO_REF:0000019, GO:0004888=PMID:17045821} Q86UZ1 CD44 antigen protein 20130413 {GO:0005515=IPI, GO:0001658=IEA, GO:0005886=TAS, GO:0051216=IEP, GO:0019221=TAS, GO:0005518=NAS, GO:0050731=IDA, GO:0044281=TAS, GO:0016323=IEA, GO:0033138=IDA, GO:0005737=IDA, GO:0016337=NAS, GO:0005540=IEA, GO:0034116=IMP, GO:0070374=IDA, GO:0043154=IMP, GO:0016055=IEA, GO:0007155=IEA, GO:1900625=IMP, GO:0030203=TAS, GO:0060333=TAS, GO:0043066=IDA, GO:0005794=IDA, GO:0009986=IDA, GO:0005975=TAS, GO:0002246=IEA, GO:0044344=IDA, GO:0060442=IEA, GO:0010628=IEA, GO:0016020=IEA, GO:0007160=NAS, GO:0005887=NAS, GO:0070487=IMP, GO:0043518=IDA, GO:0030212=TAS, GO:0004415=IDA, GO:0030214=TAS, GO:0009897=IEA, GO:0004888=IDA} Wnt receptor signaling pathway, branching involved in prostate gland morphogenesis, branching involved in ureteric bud morphogenesis, carbohydrate metabolic process, cartilage development, cell adhesion, cell-cell adhesion, cell-matrix adhesion, cellular response to fibroblast growth factor stimulus, cytokine-mediated signaling pathway, glycosaminoglycan metabolic process, hyaluronan catabolic process, hyaluronan metabolic process, interferon-gamma-mediated signaling pathway, monocyte aggregation, negative regulation of DNA damage response, signal transduction by p53 class mediator, negative regulation of apoptotic process, negative regulation of cysteine-type endopeptidase activity involved in apoptotic process, positive regulation of ERK1 and ERK2 cascade, positive regulation of gene expression, positive regulation of heterotypic cell-cell adhesion, positive regulation of monocyte aggregation, positive regulation of peptidyl-serine phosphorylation, positive regulation of peptidyl-tyrosine phosphorylation, small molecule metabolic process, wound healing involved in inflammatory response Golgi apparatus, basolateral plasma membrane, cell surface, cytoplasm, external side of plasma membrane, integral to plasma membrane, membrane, plasma membrane collagen binding, hyaluronic acid binding, hyalurononglucosaminidase activity, protein binding, transmembrane signaling receptor activity Human InterPro:IPR001231 CD46 Reactome UniProtKB {GO:0030449=Reactome:REACT_118707, GO:0005794=GO_REF:0000019, GO:0001848=GO_REF:0000019, GO:0009986=GO_REF:0000019, GO:0005886=Reactome:REACT_118673, GO:0007338=GO_REF:0000037, GO:0045916=GO_REF:0000019, GO:0016323=GO_REF:0000019, GO:0002079=GO_REF:0000039, GO:0005887=PMID:1711570, GO:0045087=Reactome:REACT_6802, GO:0019048=GO_REF:0000037, GO:0006958=GO_REF:0000037, GO:0006508=GO_REF:0000019, GO:0004872=PMID:8402913} P15529 Membrane cofactor protein protein 20130213 {GO:0030449=TAS, GO:0005794=IEA, GO:0001848=IEA, GO:0009986=IEA, GO:0005886=TAS, GO:0007338=IEA, GO:0045916=IEA, GO:0016323=IEA, GO:0002079=IEA, GO:0005887=TAS, GO:0045087=TAS, GO:0019048=IEA, GO:0006958=IEA, GO:0006508=IEA, GO:0004872=TAS} complement activation, classical pathway, innate immune response, negative regulation of complement activation, proteolysis, regulation of complement activation, single fertilization, virus-host interaction Golgi apparatus, basolateral plasma membrane, cell surface, inner acrosomal membrane, integral to plasma membrane, plasma membrane complement binding, receptor activity Human CD47 BHF-UCL UniProtKB {GO:0005515=PMID:15383453, GO:0008284=PMID:15383453, GO:0022409=PMID:15383453, GO:0005886=Reactome:REACT_24015, GO:0050900=Reactome:REACT_12051, GO:0009617=GO_REF:0000019, GO:0050766=GO_REF:0000019, GO:0007596=Reactome:REACT_604, GO:0005887=GO_REF:0000019, GO:0007229=PMID:8294396, GO:0050870=PMID:15383453, GO:0050729=GO_REF:0000019, GO:0007155=GO_REF:0000037, GO:0008228=GO_REF:0000019, GO:0070053=PMID:15700281, GO:0070062=GO_REF:0000019} Q08722 Leukocyte surface antigen CD47 protein 20081021 {GO:0005515=IPI, GO:0008284=IDA, GO:0022409=IDA, GO:0005886=TAS, GO:0050900=TAS, GO:0009617=IEA, GO:0050766=IEA, GO:0007596=TAS, GO:0005887=IEA, GO:0007229=TAS, GO:0050870=IDA, GO:0050729=IEA, GO:0007155=IEA, GO:0008228=IEA, GO:0070053=IPI, GO:0070062=IEA} blood coagulation, cell adhesion, integrin-mediated signaling pathway, leukocyte migration, opsonization, positive regulation of T cell activation, positive regulation of cell proliferation, positive regulation of cell-cell adhesion, positive regulation of inflammatory response, positive regulation of phagocytosis, response to bacterium extracellular vesicular exosome, integral to plasma membrane, plasma membrane protein binding, thrombospondin receptor activity Human UniProtKB:P07996 CD48 InterPro UniProtKB {GO:0005515=PMID:18296487, GO:0045576=GO_REF:0000019, GO:0043499=GO_REF:0000019, GO:0005886=Reactome:REACT_12018, GO:0006952=PMID:2828034, GO:0050900=Reactome:REACT_12051, GO:0003823=GO_REF:0000019, GO:0007165=GO_REF:0000019, GO:0043234=GO_REF:0000019, GO:0042110=GO_REF:0000019, GO:0007596=Reactome:REACT_604, GO:0005887=PMID:1693656, GO:0004872=GO_REF:0000002, GO:0045121=PMID:11313396, GO:0016021=GO_REF:0000002, GO:0046658=GO_REF:0000019, GO:0009897=GO_REF:0000019} Q8MGR0 CD48 antigen protein 20130413 {GO:0005515=IPI, GO:0045576=IEA, GO:0043499=IEA, GO:0005886=TAS, GO:0006952=TAS, GO:0050900=TAS, GO:0003823=IEA, GO:0007165=IEA, GO:0043234=IEA, GO:0042110=IEA, GO:0007596=TAS, GO:0005887=TAS, GO:0004872=IEA, GO:0045121=IDA, GO:0016021=IEA, GO:0046658=IEA, GO:0009897=IEA} T cell activation, blood coagulation, defense response, leukocyte migration, mast cell activation, signal transduction anchored to plasma membrane, external side of plasma membrane, integral to membrane, integral to plasma membrane, membrane raft, plasma membrane, protein complex antigen binding, eukaryotic cell surface binding, protein binding, receptor activity Human InterPro:IPR015631 CD5 MGI UniProtKB {GO:0005515=PMID:1711157, GO:0008037=PMID:1711157, GO:0005886=PMID:11390434, GO:0016020=GO_REF:0000002, GO:0005887=PMID:1711157, GO:0008283=PMID:3093892, GO:0031295=GO_REF:0000019, GO:0004872=PMID:1711157, GO:0009897=GO_REF:0000019, GO:0004888=PMID:3093892, GO:0005044=GO_REF:0000002} P06127 T-cell surface glycoprotein CD5 protein 20101102 {GO:0005515=IPI, GO:0008037=NAS, GO:0005886=IDA, GO:0016020=IEA, GO:0005887=NAS, GO:0008283=NAS, GO:0031295=IEA, GO:0004872=NAS, GO:0009897=IEA, GO:0004888=NAS, GO:0005044=IEA} T cell costimulation, cell proliferation, cell recognition external side of plasma membrane, integral to plasma membrane, membrane, plasma membrane protein binding, receptor activity, scavenger receptor activity, transmembrane signaling receptor activity Human CD52 PINC UniProtKB {GO:0045730=PMID:8223854, GO:0016020=PMID:1711975, GO:0005887=PMID:1711975, GO:0031225=GO_REF:0000037, GO:0007204=PMID:8223854} P31358 CAMPATH-1 antigen protein 20030904 {GO:0045730=NAS, GO:0016020=TAS, GO:0005887=TAS, GO:0031225=IEA, GO:0007204=IDA} elevation of cytosolic calcium ion concentration, respiratory burst anchored to membrane, integral to plasma membrane, membrane Human CD53 PINC UniProtKB {GO:0001772=PMID:21930792, GO:0005515=PMID:21930792, GO:0007165=PMID:8404042, GO:0005886=PMID:8452817, GO:0009986=GO_REF:0000019, GO:0016021=GO_REF:0000037} P19397 Leukocyte surface antigen CD53 protein 20030904 {GO:0001772=IDA, GO:0005515=IPI, GO:0007165=NAS, GO:0005886=TAS, GO:0009986=IEA, GO:0016021=IEA} signal transduction cell surface, immunological synapse, integral to membrane, plasma membrane protein binding Human CD55 Reactome UniProtKB {GO:0004857=GO_REF:0000019, GO:0045730=PMID:8223854, GO:0030449=Reactome:REACT_118707, GO:0005886=Reactome:REACT_118782, GO:0043434=GO_REF:0000019, GO:0060137=GO_REF:0000019, GO:0005576=Reactome:REACT_25290, GO:0031225=GO_REF:0000037, GO:0007283=GO_REF:0000019, GO:0007204=PMID:8223854, GO:0045916=GO_REF:0000019, GO:0016324=GO_REF:0000019, GO:0005887=PMID:2433596, GO:0045087=Reactome:REACT_6802, GO:0006958=GO_REF:0000037, GO:0045121=PMID:11313396} P08174 Complement decay-accelerating factor protein 20101029 {GO:0004857=IEA, GO:0045730=NAS, GO:0030449=TAS, GO:0005886=TAS, GO:0043434=IEA, GO:0060137=IEA, GO:0005576=TAS, GO:0031225=IEA, GO:0007283=IEA, GO:0007204=IDA, GO:0045916=IEA, GO:0016324=IEA, GO:0005887=TAS, GO:0045087=TAS, GO:0006958=IEA, GO:0045121=IDA} complement activation, classical pathway, elevation of cytosolic calcium ion concentration, innate immune response, maternal process involved in parturition, negative regulation of complement activation, regulation of complement activation, respiratory burst, response to peptide hormone stimulus, spermatogenesis anchored to membrane, apical plasma membrane, extracellular region, integral to plasma membrane, membrane raft, plasma membrane enzyme inhibitor activity Human CD58 Reactome UniProtKB {GO:0005515=PMID:7544493, GO:0016337=PMID:7544493, GO:0005886=Reactome:REACT_12031, GO:0007596=Reactome:REACT_604, GO:0005887=PMID:7544493, GO:0031225=GO_REF:0000037, GO:0050900=Reactome:REACT_12051, GO:0007155=PMID:10380930} P19256 Lymphocyte function-associated antigen 3 protein 20070515 {GO:0005515=IPI, GO:0016337=NAS, GO:0005886=TAS, GO:0007596=TAS, GO:0005887=NAS, GO:0031225=IEA, GO:0050900=TAS, GO:0007155=NAS} blood coagulation, cell adhesion, cell-cell adhesion, leukocyte migration anchored to membrane, integral to plasma membrane, plasma membrane protein binding Human CD59 IntAct UniProtKB {GO:0005515=PMID:20427317, GO:0043066=GO_REF:0000019, GO:0001848=GO_REF:0000019, GO:0005886=PMID:1381503, GO:0005615=GO_REF:0000019, GO:0031362=PMID:9724629, GO:0042383=GO_REF:0000019, GO:0016020=PMID:1381503, GO:0007596=PMID:1381503, GO:0001971=GO_REF:0000019, GO:0043218=GO_REF:0000019, GO:0042102=GO_REF:0000019, GO:0007166=PMID:7691713} P13987 CD59 glycoprotein protein 20130415 {GO:0005515=IPI, GO:0043066=IEA, GO:0001848=IEA, GO:0005886=NAS, GO:0005615=IEA, GO:0031362=IDA, GO:0042383=IEA, GO:0016020=TAS, GO:0007596=TAS, GO:0001971=IEA, GO:0043218=IEA, GO:0042102=IEA, GO:0007166=TAS} blood coagulation, cell surface receptor signaling pathway, negative regulation of activation of membrane attack complex, negative regulation of apoptotic process, positive regulation of T cell proliferation anchored to external side of plasma membrane, compact myelin, extracellular space, membrane, plasma membrane, sarcolemma complement binding, protein binding Human UniProtKB:O35587 CD5L PINC UniProtKB {GO:0006968=PMID:9045627, GO:0016020=GO_REF:0000002, GO:0006915=GO_REF:0000037, GO:0005576=PMID:14718574, GO:0005615=PMID:9045627, GO:0005044=GO_REF:0000002} O43866 CD5 antigen-like protein 20030904 {GO:0006968=TAS, GO:0016020=IEA, GO:0006915=IEA, GO:0005576=NAS, GO:0005615=TAS, GO:0005044=IEA} apoptotic process, cellular defense response extracellular region, extracellular space, membrane scavenger receptor activity Human CD6 PINC UniProtKB {GO:0009986=PMID:12493773, GO:0016020=GO_REF:0000002, GO:0005887=PMID:1919444, GO:0007155=GO_REF:0000037, GO:0005044=GO_REF:0000002} P30203 T-cell differentiation antigen CD6 protein 20030904 {GO:0009986=IDA, GO:0016020=IEA, GO:0005887=TAS, GO:0007155=IEA, GO:0005044=IEA} cell adhesion cell surface, integral to plasma membrane, membrane scavenger receptor activity Human CD63 Reactome UniProtKB {GO:0031088=Reactome:REACT_21266, GO:0009986=PMID:15647390, GO:0005886=Reactome:REACT_21266, GO:0005770=GO_REF:0000019, GO:0030168=Reactome:REACT_798, GO:0005765=GO_REF:0000039, GO:0005764=GO_REF:0000019, GO:2000680=PMID:15647390, GO:0005887=PMID:1993697, GO:0007596=Reactome:REACT_604, GO:0031902=GO_REF:0000039, GO:0002576=Reactome:REACT_318, GO:0016021=GO_REF:0000038, GO:0034613=PMID:15647390, GO:0010008=PMID:15229288} P08962 CD63 antigen protein 20041004 {GO:0031088=TAS, GO:0009986=IDA, GO:0005886=TAS, GO:0005770=IEA, GO:0030168=TAS, GO:0005765=IEA, GO:0005764=IEA, GO:2000680=IDA, GO:0005887=TAS, GO:0007596=TAS, GO:0031902=IEA, GO:0002576=TAS, GO:0016021=IEA, GO:0034613=IDA, GO:0010008=IDA} blood coagulation, cellular protein localization, platelet activation, platelet degranulation, regulation of rubidium ion transport cell surface, endosome membrane, integral to membrane, integral to plasma membrane, late endosome, late endosome membrane, lysosomal membrane, lysosome, plasma membrane, platelet dense granule membrane Human CD68 PINC UniProtKB {GO:0005886=GO_REF:0000039, GO:0016020=PMID:7680921, GO:0071310=GO_REF:0000019, GO:0016021=GO_REF:0000037, GO:0005765=GO_REF:0000039, GO:0010008=GO_REF:0000039} P34810 Macrosialin protein 20030904 {GO:0005886=IEA, GO:0016020=TAS, GO:0071310=IEA, GO:0016021=IEA, GO:0005765=IEA, GO:0010008=IEA} cellular response to organic substance endosome membrane, integral to membrane, lysosomal membrane, membrane, plasma membrane Human CD69 PINC UniProtKB {GO:0005887=PMID:8340758, GO:0030246=GO_REF:0000002, GO:0035690=GO_REF:0000019, GO:0009897=GO_REF:0000019, GO:0004888=PMID:8340758} Q07108 Early activation antigen CD69 protein 20030904 {GO:0005887=TAS, GO:0030246=IEA, GO:0035690=IEA, GO:0009897=IEA, GO:0004888=TAS} cellular response to drug external side of plasma membrane, integral to plasma membrane carbohydrate binding, transmembrane signaling receptor activity Human CD7 PINC UniProtKB {GO:0006955=PMID:11485208, GO:0042110=PMID:11485208, GO:0048873=GO_REF:0000019, GO:0005886=PMID:3258561, GO:0016020=PMID:3501369, GO:0004872=PMID:11485208, GO:0016021=PMID:11485208, GO:0007169=PMID:11485208} P09564 T-cell antigen CD7 protein 20030904 {GO:0006955=TAS, GO:0042110=TAS, GO:0048873=IEA, GO:0005886=TAS, GO:0016020=TAS, GO:0004872=TAS, GO:0016021=TAS, GO:0007169=NAS} T cell activation, homeostasis of number of cells within a tissue, immune response, transmembrane receptor protein tyrosine kinase signaling pathway integral to membrane, membrane, plasma membrane receptor activity Human CD70 BHF-UCL UniProtKB {GO:0005515=PMID:12324477, GO:0005164=GO_REF:0000002, GO:0005886=PMID:11920585, GO:0008283=PMID:8120384, GO:0005102=PMID:8120384, GO:0007267=PMID:8387892, GO:0006917=PMID:9177220, GO:0002020=PMID:12777399, GO:0005125=GO_REF:0000037, GO:0005615=GO_REF:0000037, GO:0007165=PMID:8387892, GO:0006955=GO_REF:0000002, GO:0016020=GO_REF:0000002, GO:0005887=PMID:8120384} P32970 CD70 antigen protein 20110220 {GO:0005515=IPI, GO:0005164=IEA, GO:0005886=IDA, GO:0008283=TAS, GO:0005102=TAS, GO:0007267=TAS, GO:0006917=IDA, GO:0002020=IPI, GO:0005125=IEA, GO:0005615=IEA, GO:0007165=TAS, GO:0006955=IEA, GO:0016020=IEA, GO:0005887=TAS} cell proliferation, cell-cell signaling, immune response, induction of apoptosis, signal transduction extracellular space, integral to plasma membrane, membrane, plasma membrane cytokine activity, protease binding, protein binding, receptor binding, tumor necrosis factor receptor binding Human UniProtKB:P78325 CD72 Reactome UniProtKB {GO:0005515=PMID:1711157, GO:0005886=Reactome:REACT_19336, GO:0007411=Reactome:REACT_18266, GO:0005887=PMID:1711157, GO:0005102=PMID:1711157, GO:0030246=GO_REF:0000002, GO:0007155=PMID:1711157, GO:0004888=PMID:1711157} P21854 B-cell differentiation antigen CD72 protein 20070516 {GO:0005515=IPI, GO:0005886=TAS, GO:0007411=TAS, GO:0005887=IDA, GO:0005102=TAS, GO:0030246=IEA, GO:0007155=TAS, GO:0004888=NAS} axon guidance, cell adhesion integral to plasma membrane, plasma membrane carbohydrate binding, protein binding, receptor binding, transmembrane signaling receptor activity Human CD74 BHF-UCL UniProtKB {GO:0016064=GO_REF:0000024, GO:0043030=PMID:12782713, GO:0050731=PMID:17045821, GO:0005765=Reactome:REACT_121306, GO:0006886=GO_REF:0000024, GO:0042802=PMID:12782713, GO:0005622=PMID:12782713, GO:0001516=PMID:12782713, GO:0002906=GO_REF:0000019, GO:0070374=PMID:17045821, GO:0004896=PMID:17045821, GO:0009986=PMID:17045821, GO:0006952=GO_REF:0000019, GO:0019955=PMID:17567581, GO:0090023=GO_REF:0000024, GO:0051085=GO_REF:0000019, GO:0002830=GO_REF:0000019, GO:0035718=PMID:17045821, GO:0009897=GO_REF:0000019, GO:0050998=GO_REF:0000019, GO:0042289=GO_REF:0000024, GO:0005886=Reactome:REACT_121063, GO:0008283=PMID:12782713, GO:0030890=PMID:12782713, GO:0048146=PMID:12782713, GO:0000187=GO_REF:0000019, GO:0019886=Reactome:REACT_121399, GO:0006955=GO_REF:0000002, GO:0001540=PMID:19849849, GO:0019883=PMID:10981873, GO:0019882=GO_REF:0000002, GO:0001961=PMID:12782713, GO:0045581=GO_REF:0000019, GO:0071556=Reactome:REACT_121334, GO:0045582=GO_REF:0000019, GO:0030658=Reactome:REACT_121063, GO:0043202=Reactome:REACT_121161, GO:0005773=PMID:19849849, GO:0012507=Reactome:REACT_121121, GO:0043066=PMID:17045821, GO:0005771=GO_REF:0000019, GO:0002792=PMID:19849849, GO:0035693=GO_REF:0000019, GO:0042613=GO_REF:0000024, GO:0002606=GO_REF:0000019, GO:0032588=Reactome:REACT_121309, GO:0045059=GO_REF:0000019, GO:0035691=GO_REF:0000019, GO:0045058=PMID:10981873, GO:2000343=GO_REF:0000024, GO:0035692=PMID:17045821, GO:0030666=Reactome:REACT_121177, GO:0007165=PMID:12782713, GO:0006461=GO_REF:0000024, GO:0016020=GO_REF:0000002, GO:0000139=Reactome:REACT_121309, GO:0060907=GO_REF:0000024, GO:0043518=PMID:17045821, GO:0045060=GO_REF:0000019, GO:0016021=PMID:12782713, GO:0030669=Reactome:REACT_121177} P04233 HLA class II histocompatibility antigen gamma chain protein 20110228 {GO:0016064=ISS, GO:0043030=NAS, GO:0050731=IDA, GO:0005765=TAS, GO:0006886=ISS, GO:0042802=TAS, GO:0005622=TAS, GO:0001516=IDA, GO:0002906=IEA, GO:0070374=IDA, GO:0004896=IDA, GO:0009986=IDA, GO:0006952=IEA, GO:0019955=IPI, GO:0090023=ISS, GO:0051085=IEA, GO:0002830=IEA, GO:0035718=IPI, GO:0009897=IEA, GO:0050998=IEA, GO:0042289=ISS, GO:0005886=TAS, GO:0008283=IDA, GO:0030890=IMP, GO:0048146=IMP, GO:0000187=IEA, GO:0019886=TAS, GO:0006955=IEA, GO:0001540=IPI, GO:0019883=NAS, GO:0019882=IEA, GO:0001961=IMP, GO:0045581=IEA, GO:0071556=TAS, GO:0045582=IEA, GO:0030658=TAS, GO:0043202=TAS, GO:0005773=IDA, GO:0012507=TAS, GO:0043066=IMP, GO:0005771=IEA, GO:0002792=IDA, GO:0035693=IEA, GO:0042613=ISS, GO:0002606=IEA, GO:0032588=TAS, GO:0045059=IEA, GO:0035691=IEA, GO:0045058=NAS, GO:2000343=ISS, GO:0035692=IDA, GO:0030666=TAS, GO:0007165=IDA, GO:0006461=ISS, GO:0016020=IEA, GO:0000139=TAS, GO:0060907=ISS, GO:0043518=IDA, GO:0045060=IEA, GO:0016021=IDA, GO:0030669=TAS} T cell selection, activation of MAPK activity, antigen processing and presentation, antigen processing and presentation of endogenous antigen, antigen processing and presentation of exogenous peptide antigen via MHC class II, cell proliferation, chaperone mediated protein folding requiring cofactor, defense response, immune response, immunoglobulin mediated immune response, intracellular protein transport, macrophage migration inhibitory factor signaling pathway, negative regulation of DNA damage response, signal transduction by p53 class mediator, negative regulation of T cell differentiation, negative regulation of apoptotic process, negative regulation of mature B cell apoptotic process, negative regulation of peptide secretion, negative thymic T cell selection, positive regulation of B cell proliferation, positive regulation of ERK1 and ERK2 cascade, positive regulation of T cell differentiation, positive regulation of chemokine (C-X-C motif) ligand 2 production, positive regulation of cytokine-mediated signaling pathway, positive regulation of dendritic cell antigen processing and presentation, positive regulation of fibroblast proliferation, positive regulation of macrophage cytokine production, positive regulation of neutrophil chemotaxis, positive regulation of peptidyl-tyrosine phosphorylation, positive regulation of type 2 immune response, positive thymic T cell selection, prostaglandin biosynthetic process, protein complex assembly, regulation of macrophage activation, signal transduction ER to Golgi transport vesicle membrane, Golgi membrane, MHC class II protein complex, NOS2-CD74 complex, cell surface, clathrin-coated endocytic vesicle membrane, endocytic vesicle membrane, external side of plasma membrane, integral to lumenal side of endoplasmic reticulum membrane, integral to membrane, intracellular, lysosomal lumen, lysosomal membrane, macrophage migration inhibitory factor receptor complex, membrane, multivesicular body, plasma membrane, trans-Golgi network membrane, transport vesicle membrane, vacuole MHC class II protein binding, beta-amyloid binding, cytokine binding, cytokine receptor activity, identical protein binding, macrophage migration inhibitory factor binding, nitric-oxide synthase binding Human UniProtKB:P04441 CD79A Reactome UniProtKB {GO:0050853=GO_REF:0000024, GO:0042113=GO_REF:0000024, GO:0019815=GO_REF:0000024, GO:0005886=Reactome:REACT_118834, GO:0042100=GO_REF:0000024, GO:0005771=GO_REF:0000024, GO:0030183=GO_REF:0000024, GO:0045121=GO_REF:0000024, GO:0016021=GO_REF:0000037, GO:0009897=GO_REF:0000024, GO:0004888=GO_REF:0000002} P11912 B-cell antigen receptor complex-associated protein alpha chain protein 20101102 {GO:0050853=ISS, GO:0042113=ISS, GO:0019815=ISS, GO:0005886=TAS, GO:0042100=ISS, GO:0005771=ISS, GO:0030183=ISS, GO:0045121=ISS, GO:0016021=IEA, GO:0009897=ISS, GO:0004888=IEA} B cell activation, B cell differentiation, B cell proliferation, B cell receptor signaling pathway B cell receptor complex, external side of plasma membrane, integral to membrane, membrane raft, multivesicular body, plasma membrane transmembrane signaling receptor activity Human CD79B HPA UniProtKB {GO:0050853=GO_REF:0000019, GO:0007165=PMID:8486355, GO:0019815=GO_REF:0000019, GO:0005737=GO_REF:0000052, GO:0006955=PMID:8486355, GO:0005794=GO_REF:0000052, GO:0005886=GO_REF:0000052, GO:0005887=PMID:8486355, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0009897=GO_REF:0000019, GO:0004888=GO_REF:0000002} P40259 B-cell antigen receptor complex-associated protein beta chain protein 20080205 {GO:0050853=IEA, GO:0007165=TAS, GO:0019815=IEA, GO:0005737=IDA, GO:0006955=TAS, GO:0005794=IDA, GO:0005886=IDA, GO:0005887=TAS, GO:0005730=IDA, GO:0005634=IDA, GO:0009897=IEA, GO:0004888=IEA} B cell receptor signaling pathway, immune response, signal transduction B cell receptor complex, Golgi apparatus, cytoplasm, external side of plasma membrane, integral to plasma membrane, nucleolus, nucleus, plasma membrane transmembrane signaling receptor activity Human CD80 UniProtKB UniProtKB {GO:0005515=PMID:21982860, GO:0048011=Reactome:REACT_11061, GO:0045425=PMID:9915850, GO:0005886=Reactome:REACT_147854, GO:0048015=Reactome:REACT_12464, GO:0031295=Reactome:REACT_19344, GO:0007267=PMID:9915850, GO:0050731=PMID:9915850, GO:0009967=PMID:9915850, GO:0015026=PMID:9915850, GO:0035556=PMID:9915850, GO:0045086=PMID:9915850, GO:0042110=PMID:9915850, GO:0007173=Reactome:REACT_9417, GO:0008543=Reactome:REACT_9470, GO:0045087=Reactome:REACT_6802, GO:0019048=GO_REF:0000037, GO:0045627=PMID:9915850, GO:0046641=GO_REF:0000019, GO:0016021=GO_REF:0000038, GO:0045893=PMID:9915850, GO:0009897=GO_REF:0000019} Q5DTB0 Costimulatory factor CD80 type 1 protein 20130413 {GO:0005515=IPI, GO:0048011=TAS, GO:0045425=NAS, GO:0005886=TAS, GO:0048015=TAS, GO:0031295=TAS, GO:0007267=IC, GO:0050731=IDA, GO:0009967=NAS, GO:0015026=NAS, GO:0035556=NAS, GO:0045086=NAS, GO:0042110=IC, GO:0007173=TAS, GO:0008543=TAS, GO:0045087=TAS, GO:0019048=IEA, GO:0045627=NAS, GO:0046641=IEA, GO:0016021=IEA, GO:0045893=NAS, GO:0009897=IEA} T cell activation, T cell costimulation, cell-cell signaling, epidermal growth factor receptor signaling pathway, fibroblast growth factor receptor signaling pathway, innate immune response, intracellular signal transduction, neurotrophin TRK receptor signaling pathway, phosphatidylinositol-mediated signaling, positive regulation of T-helper 1 cell differentiation, positive regulation of alpha-beta T cell proliferation, positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, positive regulation of interleukin-2 biosynthetic process, positive regulation of peptidyl-tyrosine phosphorylation, positive regulation of signal transduction, positive regulation of transcription, DNA-dependent, virus-host interaction external side of plasma membrane, integral to membrane, plasma membrane coreceptor activity, protein binding Human UniProtKB-KW:KW-0812 CD81 Reactome UniProtKB {GO:0005515=PMID:11504738, GO:0001772=PMID:21930792, GO:0008284=PMID:14676841, GO:0005886=Reactome:REACT_11121, GO:0006661=PMID:14676841, GO:0008283=PMID:1695320, GO:0046488=PMID:14676841, GO:0050731=PMID:14676841, GO:0046718=PMID:14676841, GO:0000187=PMID:14676841, GO:0008104=PMID:14676841, GO:0005887=PMID:14676841, GO:0050776=Reactome:REACT_11152, GO:0016021=GO_REF:0000038, GO:0043128=PMID:14676841, GO:0046813=PMID:14676841} P60033 CD81 antigen protein 20070515 {GO:0005515=IPI, GO:0001772=IDA, GO:0008284=IDA, GO:0005886=TAS, GO:0006661=IDA, GO:0008283=TAS, GO:0046488=IDA, GO:0050731=IDA, GO:0046718=TAS, GO:0000187=IDA, GO:0008104=IDA, GO:0005887=IDA, GO:0050776=TAS, GO:0016021=IEA, GO:0043128=IDA, GO:0046813=TAS} activation of MAPK activity, cell proliferation, phosphatidylinositol biosynthetic process, phosphatidylinositol metabolic process, positive regulation of 1-phosphatidylinositol 4-kinase activity, positive regulation of cell proliferation, positive regulation of peptidyl-tyrosine phosphorylation, protein localization, regulation of immune response, viral entry into host cell, virion attachment, binding of host cell surface receptor immunological synapse, integral to membrane, integral to plasma membrane, plasma membrane protein binding Human CD82 IntAct UniProtKB {GO:0005515=PMID:15205336, GO:0005886=PMID:7754374, GO:0005887=PMID:1842498, GO:0016021=GO_REF:0000038} P27701 CD82 antigen protein 20130415 {GO:0005515=IPI, GO:0005886=TAS, GO:0005887=TAS, GO:0016021=IEA} integral to membrane, integral to plasma membrane, plasma membrane protein binding Human UniProtKB:Q8TAA9 CD83 PINC UniProtKB {GO:0007165=PMID:9310491, GO:0014070=GO_REF:0000019, GO:0005886=PMID:9310491, GO:0032733=GO_REF:0000019, GO:0005887=PMID:8422464, GO:0032743=GO_REF:0000019, GO:0006959=PMID:8422464, GO:0043372=GO_REF:0000019, GO:0032713=GO_REF:0000019, GO:0006952=PMID:1378080, GO:0009897=GO_REF:0000019} Q01151 CD83 antigen protein 20030904 {GO:0007165=TAS, GO:0014070=IEA, GO:0005886=TAS, GO:0032733=IEA, GO:0005887=TAS, GO:0032743=IEA, GO:0006959=TAS, GO:0043372=IEA, GO:0032713=IEA, GO:0006952=TAS, GO:0009897=IEA} defense response, humoral immune response, negative regulation of interleukin-4 production, positive regulation of CD4-positive, alpha-beta T cell differentiation, positive regulation of interleukin-10 production, positive regulation of interleukin-2 production, response to organic cyclic compound, signal transduction external side of plasma membrane, integral to plasma membrane, plasma membrane Human CD84 Reactome UniProtKB {GO:0005886=Reactome:REACT_12027, GO:0007596=Reactome:REACT_604, GO:0005887=PMID:9310491, GO:0006952=PMID:9310491, GO:0004872=GO_REF:0000002, GO:0050900=Reactome:REACT_12051, GO:0007156=PMID:7797269} Q9UIB8 SLAM family member 5 protein 20071111 {GO:0005886=TAS, GO:0007596=TAS, GO:0005887=TAS, GO:0006952=TAS, GO:0004872=IEA, GO:0050900=TAS, GO:0007156=TAS} blood coagulation, defense response, homophilic cell adhesion, leukocyte migration integral to plasma membrane, plasma membrane receptor activity Human CD86 IntAct UniProtKB {GO:0005515=PMID:21982860, GO:0008284=PMID:7513726, GO:0005886=Reactome:REACT_147854, GO:0045404=PMID:9915850, GO:0031295=Reactome:REACT_19344, GO:0007267=PMID:9915850, GO:0043231=GO_REF:0000019, GO:0006955=PMID:7694363, GO:0051607=GO_REF:0000019, GO:0007173=Reactome:REACT_9417, GO:0004872=PMID:7694363, GO:0045630=PMID:9915850, GO:0043017=PMID:9915850, GO:0048011=Reactome:REACT_11061, GO:0048015=Reactome:REACT_12464, GO:0015026=PMID:9915850, GO:0002224=GO_REF:0000019, GO:0045086=PMID:9915850, GO:0042113=GO_REF:0000019, GO:0042110=PMID:9915850, GO:0008543=Reactome:REACT_9470, GO:0019048=GO_REF:0000037, GO:0045087=Reactome:REACT_6802, GO:0016021=PMID:9915850, GO:0045893=PMID:9915850, GO:0009897=GO_REF:0000019} P42081 T-lymphocyte activation antigen CD86 protein 20130415 {GO:0005515=IPI, GO:0008284=TAS, GO:0005886=TAS, GO:0045404=NAS, GO:0031295=TAS, GO:0007267=IC, GO:0043231=IEA, GO:0006955=TAS, GO:0051607=IEA, GO:0007173=TAS, GO:0004872=TAS, GO:0045630=NAS, GO:0043017=NAS, GO:0048011=TAS, GO:0048015=TAS, GO:0015026=NAS, GO:0002224=IEA, GO:0045086=NAS, GO:0042113=IEA, GO:0042110=IC, GO:0008543=TAS, GO:0019048=IEA, GO:0045087=TAS, GO:0016021=IC, GO:0045893=NAS, GO:0009897=IEA} B cell activation, T cell activation, T cell costimulation, cell-cell signaling, defense response to virus, epidermal growth factor receptor signaling pathway, fibroblast growth factor receptor signaling pathway, immune response, innate immune response, neurotrophin TRK receptor signaling pathway, phosphatidylinositol-mediated signaling, positive regulation of T-helper 2 cell differentiation, positive regulation of cell proliferation, positive regulation of interleukin-2 biosynthetic process, positive regulation of interleukin-4 biosynthetic process, positive regulation of lymphotoxin A biosynthetic process, positive regulation of transcription, DNA-dependent, toll-like receptor signaling pathway, virus-host interaction external side of plasma membrane, integral to membrane, intracellular membrane-bounded organelle, plasma membrane coreceptor activity, protein binding, receptor activity Human UniProtKB:P16410 CD8A Reactome UniProtKB {GO:0005515=PMID:2470098, GO:0042288=PMID:11131152, GO:0005886=Reactome:REACT_11080, GO:0019901=GO_REF:0000019, GO:0005576=GO_REF:0000039, GO:0015026=PMID:11131152, GO:0042803=GO_REF:0000019, GO:0050850=GO_REF:0000019, GO:0006955=PMID:11131152, GO:0045065=GO_REF:0000019, GO:0051607=GO_REF:0000019, GO:0042110=PMID:9830036, GO:0016020=GO_REF:0000038, GO:0005887=PMID:2496167, GO:0019882=PMID:2496167, GO:0042101=PMID:11131152, GO:0050776=Reactome:REACT_11152, GO:0016021=GO_REF:0000038, GO:0007169=PMID:9830036, GO:0009897=PMID:17213291, GO:0002456=GO_REF:0000019} P01732 T-cell surface glycoprotein CD8 alpha chain protein 20070514 {GO:0005515=IPI, GO:0042288=NAS, GO:0005886=TAS, GO:0019901=IEA, GO:0005576=IEA, GO:0015026=NAS, GO:0042803=IEA, GO:0050850=IEA, GO:0006955=NAS, GO:0045065=IEA, GO:0051607=IEA, GO:0042110=NAS, GO:0016020=IEA, GO:0005887=NAS, GO:0019882=NAS, GO:0042101=NAS, GO:0050776=TAS, GO:0016021=IEA, GO:0007169=NAS, GO:0009897=IDA, GO:0002456=IEA} T cell activation, T cell mediated immunity, antigen processing and presentation, cytotoxic T cell differentiation, defense response to virus, immune response, positive regulation of calcium-mediated signaling, regulation of immune response, transmembrane receptor protein tyrosine kinase signaling pathway T cell receptor complex, external side of plasma membrane, extracellular region, integral to membrane, integral to plasma membrane, membrane, plasma membrane MHC class I protein binding, coreceptor activity, protein binding, protein homodimerization activity, protein kinase binding Human CD8B Reactome UniProtKB {GO:0005515=PMID:2493728, GO:0042288=PMID:11131152, GO:0005886=Reactome:REACT_11125, GO:0005576=GO_REF:0000039, GO:0015026=PMID:11131152, GO:0050690=Reactome:REACT_11200, GO:0006955=PMID:11131152, GO:0042110=PMID:9830036, GO:0005887=PMID:3145195, GO:0042101=PMID:11131152, GO:0031901=Reactome:REACT_11144, GO:0050776=Reactome:REACT_11152, GO:0016032=Reactome:REACT_6185, GO:0007169=PMID:9830036, GO:0009897=GO_REF:0000019} P10966 T-cell surface glycoprotein CD8 beta chain protein 20130111 {GO:0005515=IPI, GO:0042288=NAS, GO:0005886=TAS, GO:0005576=IEA, GO:0015026=NAS, GO:0050690=TAS, GO:0006955=NAS, GO:0042110=NAS, GO:0005887=TAS, GO:0042101=NAS, GO:0031901=TAS, GO:0050776=TAS, GO:0016032=TAS, GO:0007169=NAS, GO:0009897=IEA} T cell activation, immune response, regulation of defense response to virus by virus, regulation of immune response, transmembrane receptor protein tyrosine kinase signaling pathway, viral reproduction T cell receptor complex, early endosome membrane, external side of plasma membrane, extracellular region, integral to plasma membrane, plasma membrane MHC class I protein binding, coreceptor activity, protein binding Human CD9 Reactome UniProtKB {GO:0005515=PMID:11504738, GO:0008285=GO_REF:0000019, GO:0005886=Reactome:REACT_21394, GO:0030913=GO_REF:0000024, GO:0030168=Reactome:REACT_798, GO:0006928=PMID:8478605, GO:0016324=GO_REF:0000019, GO:0005178=GO_REF:0000019, GO:0007596=Reactome:REACT_604, GO:0005887=PMID:2037603, GO:0007342=PMID:14575715, GO:0007420=GO_REF:0000019, GO:0014003=GO_REF:0000019, GO:0002576=Reactome:REACT_318, GO:0009414=GO_REF:0000019, GO:0031092=Reactome:REACT_21394, GO:0016021=GO_REF:0000038, GO:0007155=PMID:7511626, GO:0009897=GO_REF:0000019} P21926 CD9 antigen protein 20100720 {GO:0005515=IPI, GO:0008285=IEA, GO:0005886=TAS, GO:0030913=ISS, GO:0030168=TAS, GO:0006928=IDA, GO:0016324=IEA, GO:0005178=IEA, GO:0007596=TAS, GO:0005887=NAS, GO:0007342=IDA, GO:0007420=IEA, GO:0014003=IEA, GO:0002576=TAS, GO:0009414=IEA, GO:0031092=TAS, GO:0016021=IEA, GO:0007155=IDA, GO:0009897=IEA} blood coagulation, brain development, cell adhesion, cellular component movement, fusion of sperm to egg plasma membrane, negative regulation of cell proliferation, oligodendrocyte development, paranodal junction assembly, platelet activation, platelet degranulation, response to water deprivation apical plasma membrane, external side of plasma membrane, integral to membrane, integral to plasma membrane, plasma membrane, platelet alpha granule membrane integrin binding, protein binding Human CD93 LIFEdb UniProtKB {GO:0006909=PMID:9047234, GO:0005515=PMID:15459234, GO:0009986=GO_REF:0000019, GO:0005886=GO_REF:0000054, GO:0005509=GO_REF:0000002, GO:0001849=PMID:11781389, GO:0016337=PMID:11994479, GO:0042116=PMID:9047234, GO:0019048=GO_REF:0000037, GO:0030246=GO_REF:0000002, GO:0016023=GO_REF:0000019, GO:0004872=PMID:9047234, GO:0016021=PMID:9047234} Q9NPY3 Complement component C1q receptor protein 20100607 {GO:0006909=NAS, GO:0005515=IPI, GO:0009986=IEA, GO:0005886=IDA, GO:0005509=IEA, GO:0001849=IDA, GO:0016337=IDA, GO:0042116=NAS, GO:0019048=IEA, GO:0030246=IEA, GO:0016023=IEA, GO:0004872=NAS, GO:0016021=IC} cell-cell adhesion, macrophage activation, phagocytosis, virus-host interaction cell surface, cytoplasmic membrane-bounded vesicle, integral to membrane, plasma membrane calcium ion binding, carbohydrate binding, complement component C1q binding, protein binding, receptor activity Human CD96 Reactome UniProtKB {GO:0006955=PMID:1313846, GO:0005886=Reactome:REACT_11207, GO:0005887=PMID:1313846, GO:0050776=Reactome:REACT_11152, GO:0007155=GO_REF:0000037} P40200 T-cell surface protein tactile protein 20130204 {GO:0006955=TAS, GO:0005886=TAS, GO:0005887=TAS, GO:0050776=TAS, GO:0007155=IEA} cell adhesion, immune response, regulation of immune response integral to plasma membrane, plasma membrane Human CD97 Reactome UniProtKB {GO:0005886=Reactome:REACT_25290, GO:0004930=GO_REF:0000037, GO:0005509=GO_REF:0000002, GO:0007267=PMID:7636245, GO:0006928=PMID:7636245, GO:0005615=GO_REF:0000039, GO:0006955=PMID:7636245, GO:0006954=PMID:8955192, GO:0016020=GO_REF:0000002, GO:0007186=PMID:8955192, GO:0007218=GO_REF:0000002, GO:0005887=PMID:8955192, GO:0007155=GO_REF:0000037, GO:0007166=PMID:7636245, GO:0004888=PMID:7636245} P48960 CD97 antigen protein 20091026 {GO:0005886=TAS, GO:0004930=IEA, GO:0005509=IEA, GO:0007267=TAS, GO:0006928=TAS, GO:0005615=IEA, GO:0006955=TAS, GO:0006954=TAS, GO:0016020=IEA, GO:0007186=TAS, GO:0007218=IEA, GO:0005887=TAS, GO:0007155=IEA, GO:0007166=TAS, GO:0004888=TAS} G-protein coupled receptor signaling pathway, cell adhesion, cell surface receptor signaling pathway, cell-cell signaling, cellular component movement, immune response, inflammatory response, neuropeptide signaling pathway extracellular space, integral to plasma membrane, membrane, plasma membrane G-protein coupled receptor activity, calcium ion binding, transmembrane signaling receptor activity Human CD99 PINC UniProtKB {GO:0005737=PMID:2479542, GO:0005886=PMID:2465491, GO:0005887=PMID:2479542, GO:0007155=GO_REF:0000037} P14209 CD99 antigen protein 20030904 {GO:0005737=TAS, GO:0005886=TAS, GO:0005887=TAS, GO:0007155=IEA} cell adhesion cytoplasm, integral to plasma membrane, plasma membrane Human CD99L2 UniProtKB UniProtKB {GO:0030054=GO_REF:0000039, GO:0005886=GO_REF:0000039, GO:0016021=GO_REF:0000037, GO:0007155=GO_REF:0000037} Q8TCZ2 CD99 antigen-like protein 2 protein 20130413 {GO:0030054=IEA, GO:0005886=IEA, GO:0016021=IEA, GO:0007155=IEA} cell adhesion cell junction, integral to membrane, plasma membrane Human UniProtKB-SubCell:SL-0038 CDA Reactome UniProtKB {GO:0030308=PMID:9596658, GO:0009972=PMID:9596658, GO:0045980=PMID:9596658, GO:0019858=PMID:7923172, GO:0055086=Reactome:REACT_1698, GO:0005576=PMID:9596658, GO:0044281=Reactome:REACT_111217, GO:0043097=Reactome:REACT_655, GO:0008655=PMID:9596658, GO:0042803=PMID:15689149, GO:0005829=Reactome:REACT_376, GO:0051289=PMID:9596658, GO:0001882=PMID:15689149, GO:0004126=Reactome:REACT_376, GO:0008270=PMID:9596658, GO:0006206=Reactome:REACT_957, GO:0007166=PMID:9596658} P32320 Cytidine deaminase protein 20130213 {GO:0030308=IDA, GO:0009972=IDA, GO:0045980=IDA, GO:0019858=TAS, GO:0055086=TAS, GO:0005576=TAS, GO:0044281=TAS, GO:0043097=TAS, GO:0008655=NAS, GO:0042803=IDA, GO:0005829=TAS, GO:0051289=IDA, GO:0001882=IDA, GO:0004126=EXP, GO:0008270=TAS, GO:0006206=TAS, GO:0007166=NAS} cell surface receptor signaling pathway, cytidine deamination, cytosine metabolic process, negative regulation of cell growth, negative regulation of nucleotide metabolic process, nucleobase-containing small molecule metabolic process, protein homotetramerization, pyrimidine nucleobase metabolic process, pyrimidine nucleoside salvage, pyrimidine-containing compound salvage, small molecule metabolic process cytosol, extracellular region cytidine deaminase activity, nucleoside binding, protein homodimerization activity, zinc ion binding Human CDAN1 UniProtKB UniProtKB {GO:0005515=PMID:22407294, GO:0005737=PMID:22407294, GO:0031497=PMID:22407294, GO:0005634=PMID:22407294, GO:0008156=PMID:22407294, GO:0016021=GO_REF:0000037} Q8IWY9 Codanin-1 protein 20121123 {GO:0005515=IPI, GO:0005737=IDA, GO:0031497=IMP, GO:0005634=IDA, GO:0008156=IMP, GO:0016021=IEA} chromatin assembly, negative regulation of DNA replication cytoplasm, integral to membrane, nucleus protein binding Human CDC123 HGNC UniProtKB {GO:0007346=PMID:15319434, GO:0008284=PMID:8601400, GO:0005737=PMID:10942595, GO:0007050=PMID:8601400, GO:0000080=GO_REF:0000019, GO:0051301=GO_REF:0000037} O75794 Cell division cycle protein 123 homolog protein 20071023 {GO:0007346=ISS, GO:0008284=TAS, GO:0005737=IDA, GO:0007050=TAS, GO:0000080=IEA, GO:0051301=IEA} G1 phase of mitotic cell cycle, cell cycle arrest, cell division, positive regulation of cell proliferation, regulation of mitotic cell cycle cytoplasm Human UniProtKB:Q05791 CDC14A HPA UniProtKB {GO:0005515=PMID:16221885, GO:0005813=PMID:21399614, GO:0007049=GO_REF:0000037, GO:0005737=GO_REF:0000052, GO:0008283=PMID:9367992, GO:0005819=GO_REF:0000039, GO:0005730=GO_REF:0000052, GO:0004721=PMID:9367992, GO:0005634=GO_REF:0000052, GO:0008138=GO_REF:0000002, GO:0004725=GO_REF:0000003, GO:0051301=GO_REF:0000037} Q9UNH5 Dual specificity protein phosphatase CDC14A protein 20101115 {GO:0005515=IPI, GO:0005813=IDA, GO:0007049=IEA, GO:0005737=IDA, GO:0008283=TAS, GO:0005819=IEA, GO:0005730=IDA, GO:0004721=TAS, GO:0005634=IDA, GO:0008138=IEA, GO:0004725=IEA, GO:0051301=IEA} cell cycle, cell division, cell proliferation centrosome, cytoplasm, nucleolus, nucleus, spindle phosphoprotein phosphatase activity, protein binding, protein tyrosine phosphatase activity, protein tyrosine/serine/threonine phosphatase activity Human CDC14B GOC UniProtKB {GO:0051488=PMID:18662541, GO:0031965=GO_REF:0000052, GO:0006470=PMID:18662541, GO:0006281=GO_REF:0000037, GO:0031572=PMID:18662541, GO:0005730=PMID:18662541, GO:0005654=PMID:18662541, GO:0005634=PMID:9367992, GO:0004722=PMID:18662541, GO:0008138=GO_REF:0000002, GO:0035335=PMID:9367992, GO:0004725=PMID:9367992} O60729 Dual specificity protein phosphatase CDC14B protein 20130413 {GO:0051488=IMP, GO:0031965=IDA, GO:0006470=IMP, GO:0006281=IEA, GO:0031572=IDA, GO:0005730=IDA, GO:0005654=IDA, GO:0005634=IDA, GO:0004722=IDA, GO:0008138=IEA, GO:0035335=IDA, GO:0004725=IDA} DNA repair, G2 DNA damage checkpoint, activation of anaphase-promoting complex activity, peptidyl-tyrosine dephosphorylation, protein dephosphorylation nuclear membrane, nucleolus, nucleoplasm, nucleus protein serine/threonine phosphatase activity, protein tyrosine phosphatase activity, protein tyrosine/serine/threonine phosphatase activity Human CDC16 ENSEMBL UniProtKB {GO:0005515=PMID:21988832, GO:0007094=Reactome:REACT_2137, GO:0005813=PMID:7736578, GO:0007088=PMID:7736578, GO:0008283=PMID:7736578, GO:0051437=Reactome:REACT_6904, GO:0005819=PMID:7736578, GO:0005634=GO_REF:0000019, GO:0051436=Reactome:REACT_6785, GO:0031145=Reactome:REACT_6871, GO:0051439=Reactome:REACT_6867, GO:0005829=Reactome:REACT_9035, GO:0005737=GO_REF:0000054, GO:0007067=PMID:7736578, GO:0070979=PMID:18485873, GO:0005680=PMID:21926987, GO:0000087=Reactome:REACT_910, GO:0000075=Reactome:REACT_1538, GO:0005654=Reactome:REACT_9051, GO:0005876=PMID:7736578, GO:0000278=Reactome:REACT_152, GO:0000090=Reactome:REACT_1275, GO:0051301=GO_REF:0000038} Q7Z651 Cell division cycle protein 16 homolog protein 20130413 {GO:0005515=IPI, GO:0007094=TAS, GO:0005813=IDA, GO:0007088=TAS, GO:0008283=TAS, GO:0051437=TAS, GO:0005819=TAS, GO:0005634=IEA, GO:0051436=TAS, GO:0031145=TAS, GO:0051439=TAS, GO:0005829=TAS, GO:0005737=IDA, GO:0007067=TAS, GO:0070979=IDA, GO:0005680=IDA, GO:0000087=TAS, GO:0000075=TAS, GO:0005654=TAS, GO:0005876=IDA, GO:0000278=TAS, GO:0000090=TAS, GO:0051301=IEA} M phase of mitotic cell cycle, anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process, cell cycle checkpoint, cell division, cell proliferation, mitosis, mitotic anaphase, mitotic cell cycle, mitotic spindle assembly checkpoint, negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle, positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle, protein K11-linked ubiquitination, regulation of mitosis, regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle anaphase-promoting complex, centrosome, cytoplasm, cytosol, nucleoplasm, nucleus, spindle, spindle microtubule protein binding Human Ensembl:ENSMUSP00000047950 CDC20 IntAct UniProtKB {GO:0005515=PMID:22340593, GO:0000236=Reactome:REACT_682, GO:0007094=Reactome:REACT_2137, GO:0090129=GO_REF:0000024, GO:0048471=GO_REF:0000019, GO:0008284=GO_REF:0000019, GO:0016567=GO_REF:0000041, GO:0031145=Reactome:REACT_6871, GO:0005829=Reactome:REACT_1951, GO:0051488=PMID:11459826, GO:0031915=GO_REF:0000024, GO:0005680=PMID:11459825, GO:0000087=Reactome:REACT_910, GO:0005813=GO_REF:0000019, GO:0005819=PMID:7513050, GO:0051437=Reactome:REACT_6821, GO:0051436=Reactome:REACT_1041, GO:0008022=PMID:10700282, GO:0051439=Reactome:REACT_6867, GO:0040020=GO_REF:0000019, GO:0000922=GO_REF:0000039, GO:0007049=PMID:9682218, GO:0050773=GO_REF:0000019, GO:0000075=Reactome:REACT_1538, GO:0005654=Reactome:REACT_6891, GO:0000278=Reactome:REACT_152, GO:0019899=PMID:17443180, GO:0000090=Reactome:REACT_1275, GO:0051301=GO_REF:0000037} Q12834 Cell division cycle protein 20 homolog protein 20130415 {GO:0005515=IPI, GO:0000236=TAS, GO:0007094=TAS, GO:0090129=ISS, GO:0048471=IEA, GO:0008284=IEA, GO:0016567=IEA, GO:0031145=TAS, GO:0005829=TAS, GO:0051488=IDA, GO:0031915=ISS, GO:0005680=IDA, GO:0000087=TAS, GO:0005813=IEA, GO:0005819=TAS, GO:0051437=TAS, GO:0051436=TAS, GO:0008022=IPI, GO:0051439=TAS, GO:0040020=IEA, GO:0000922=IEA, GO:0007049=TAS, GO:0050773=IEA, GO:0000075=TAS, GO:0005654=TAS, GO:0000278=TAS, GO:0019899=IPI, GO:0000090=TAS, GO:0051301=IEA} M phase of mitotic cell cycle, activation of anaphase-promoting complex activity, anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process, cell cycle, cell cycle checkpoint, cell division, mitotic anaphase, mitotic cell cycle, mitotic prometaphase, mitotic spindle assembly checkpoint, negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle, positive regulation of cell proliferation, positive regulation of synapse maturation, positive regulation of synaptic plasticity, positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle, protein ubiquitination, regulation of dendrite development, regulation of meiosis, regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle anaphase-promoting complex, centrosome, cytosol, nucleoplasm, perinuclear region of cytoplasm, spindle, spindle pole enzyme binding, protein C-terminus binding, protein binding Human UniProtKB:Q13257 CDC23 LIFEdb UniProtKB {GO:0007094=Reactome:REACT_2137, GO:0006511=PMID:9790767, GO:0004842=PMID:12629511, GO:0007096=PMID:9790767, GO:0051437=Reactome:REACT_6904, GO:0051436=Reactome:REACT_6785, GO:0031145=Reactome:REACT_6871, GO:0051439=Reactome:REACT_6867, GO:0005829=Reactome:REACT_9035, GO:0005622=GO_REF:0000054, GO:0007049=PMID:12188893, GO:0007067=PMID:14657031, GO:0070979=PMID:18485873, GO:0005680=PMID:21926987, GO:0000087=Reactome:REACT_910, GO:0000075=Reactome:REACT_1538, GO:0005654=Reactome:REACT_9051, GO:0030071=PMID:9790767, GO:0007080=PMID:14657031, GO:0000278=Reactome:REACT_152, GO:0000080=PMID:12629511, GO:0000090=Reactome:REACT_1275, GO:0007091=PMID:9790767, GO:0051301=GO_REF:0000037} Q9UJX2 Cell division cycle protein 23 homolog protein 20100607 {GO:0007094=TAS, GO:0006511=TAS, GO:0004842=TAS, GO:0007096=TAS, GO:0051437=TAS, GO:0051436=TAS, GO:0031145=TAS, GO:0051439=TAS, GO:0005829=TAS, GO:0005622=IDA, GO:0007049=TAS, GO:0007067=IDA, GO:0070979=IDA, GO:0005680=IDA, GO:0000087=TAS, GO:0000075=TAS, GO:0005654=TAS, GO:0030071=IDA, GO:0007080=IDA, GO:0000278=TAS, GO:0000080=IDA, GO:0000090=TAS, GO:0007091=TAS, GO:0051301=IEA} G1 phase of mitotic cell cycle, M phase of mitotic cell cycle, anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process, cell cycle, cell cycle checkpoint, cell division, metaphase/anaphase transition of mitotic cell cycle, mitosis, mitotic anaphase, mitotic cell cycle, mitotic metaphase plate congression, mitotic spindle assembly checkpoint, negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle, positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle, protein K11-linked ubiquitination, regulation of exit from mitosis, regulation of mitotic metaphase/anaphase transition, regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle, ubiquitin-dependent protein catabolic process anaphase-promoting complex, cytosol, intracellular, nucleoplasm ubiquitin-protein ligase activity Human CDC25A IntAct UniProtKB {GO:0009314=PMID:21376736, GO:0005515=PMID:7644510, GO:0019901=PMID:21376736, GO:0008283=PMID:11139144, GO:0005634=GO_REF:0000019, GO:0000079=PMID:11139144, GO:0005829=Reactome:REACT_6257, GO:0006260=Reactome:REACT_6769, GO:0000084=Reactome:REACT_899, GO:0005622=GO_REF:0000002, GO:0007067=GO_REF:0000037, GO:0034644=PMID:19966869, GO:0000082=Reactome:REACT_1783, GO:0005737=GO_REF:0000019, GO:0000086=Reactome:REACT_2203, GO:0000087=GO_REF:0000002, GO:0000075=Reactome:REACT_1538, GO:0005654=Reactome:REACT_111167, GO:0000278=Reactome:REACT_152, GO:0004725=GO_REF:0000003, GO:0051301=GO_REF:0000037} P30304 M-phase inducer phosphatase 1 protein 20130415 {GO:0009314=IDA, GO:0005515=IPI, GO:0019901=IPI, GO:0008283=TAS, GO:0005634=IEA, GO:0000079=TAS, GO:0005829=TAS, GO:0006260=TAS, GO:0000084=TAS, GO:0005622=IEA, GO:0007067=IEA, GO:0034644=IDA, GO:0000082=TAS, GO:0005737=IEA, GO:0000086=TAS, GO:0000087=IEA, GO:0000075=TAS, GO:0005654=TAS, GO:0000278=TAS, GO:0004725=IEA, GO:0051301=IEA} DNA replication, G1/S transition of mitotic cell cycle, G2/M transition of mitotic cell cycle, M phase of mitotic cell cycle, S phase of mitotic cell cycle, cell cycle checkpoint, cell division, cell proliferation, cellular response to UV, mitosis, mitotic cell cycle, regulation of cyclin-dependent protein serine/threonine kinase activity, response to radiation cytoplasm, cytosol, intracellular, nucleoplasm, nucleus protein binding, protein kinase binding, protein tyrosine phosphatase activity Human UniProtKB:P31946 CDC25B GOC UniProtKB {GO:0008284=PMID:8276402, GO:0005813=PMID:15908796, GO:0019901=PMID:15908796, GO:0001556=GO_REF:0000019, GO:0035335=PMID:9188863, GO:0005829=Reactome:REACT_6257, GO:0005622=GO_REF:0000029, GO:0007067=GO_REF:0000037, GO:0045931=PMID:17332740, GO:0000922=PMID:15908796, GO:0007144=GO_REF:0000019, GO:0000086=Reactome:REACT_2203, GO:0000087=GO_REF:0000002, GO:0045860=GO_REF:0000019, GO:0005654=Reactome:REACT_6255, GO:0006468=PMID:17332740, GO:0000278=Reactome:REACT_152, GO:0004725=PMID:9188863, GO:0051301=GO_REF:0000037} P30305 M-phase inducer phosphatase 2 protein 20130413 {GO:0008284=TAS, GO:0005813=IDA, GO:0019901=IPI, GO:0001556=IEA, GO:0035335=TAS, GO:0005829=TAS, GO:0005622=NAS, GO:0007067=IEA, GO:0045931=IMP, GO:0000922=IDA, GO:0007144=IEA, GO:0000086=TAS, GO:0000087=IEA, GO:0045860=IEA, GO:0005654=TAS, GO:0006468=IDA, GO:0000278=TAS, GO:0004725=TAS, GO:0051301=IEA} G2/M transition of mitotic cell cycle, M phase of mitotic cell cycle, cell division, female meiosis I, mitosis, mitotic cell cycle, oocyte maturation, peptidyl-tyrosine dephosphorylation, positive regulation of cell proliferation, positive regulation of mitotic cell cycle, positive regulation of protein kinase activity, protein phosphorylation centrosome, cytosol, intracellular, nucleoplasm, spindle pole protein kinase binding, protein tyrosine phosphatase activity Human CDC25C GOC UniProtKB {GO:0005515=PMID:17349584, GO:0007088=PMID:1828290, GO:0019901=PMID:14968113, GO:0008283=PMID:11139144, GO:0050699=PMID:10037602, GO:0005634=PMID:14968113, GO:0000079=PMID:11139144, GO:0035335=PMID:11078813, GO:0005829=Reactome:REACT_6279, GO:0006260=Reactome:REACT_6769, GO:0005622=GO_REF:0000002, GO:0005737=GO_REF:0000019, GO:0007067=GO_REF:0000037, GO:0019048=GO_REF:0000037, GO:0000086=Reactome:REACT_2203, GO:0000087=GO_REF:0000002, GO:0051726=Reactome:REACT_1006, GO:0000075=Reactome:REACT_1538, GO:0005654=Reactome:REACT_6279, GO:0000278=Reactome:REACT_152, GO:0004725=PMID:11078813, GO:0051301=GO_REF:0000037} P30307 M-phase inducer phosphatase 3 protein 20130413 {GO:0005515=IPI, GO:0007088=TAS, GO:0019901=IPI, GO:0008283=TAS, GO:0050699=IPI, GO:0005634=IDA, GO:0000079=TAS, GO:0035335=NAS, GO:0005829=TAS, GO:0006260=TAS, GO:0005622=IEA, GO:0005737=IEA, GO:0007067=IEA, GO:0019048=IEA, GO:0000086=TAS, GO:0000087=IEA, GO:0051726=TAS, GO:0000075=TAS, GO:0005654=TAS, GO:0000278=TAS, GO:0004725=NAS, GO:0051301=IEA} DNA replication, G2/M transition of mitotic cell cycle, M phase of mitotic cell cycle, cell cycle checkpoint, cell division, cell proliferation, mitosis, mitotic cell cycle, peptidyl-tyrosine dephosphorylation, regulation of cell cycle, regulation of cyclin-dependent protein serine/threonine kinase activity, regulation of mitosis, virus-host interaction cytoplasm, cytosol, intracellular, nucleoplasm, nucleus WW domain binding, protein binding, protein kinase binding, protein tyrosine phosphatase activity Human CDC26 IntAct UniProtKB {GO:0005515=PMID:21988832, GO:0007094=Reactome:REACT_2137, GO:0051437=Reactome:REACT_6904, GO:0051436=Reactome:REACT_6785, GO:0031145=Reactome:REACT_6871, GO:0051439=Reactome:REACT_6867, GO:0005829=Reactome:REACT_9035, GO:0070979=PMID:18485873, GO:0005680=PMID:10922056, GO:0000087=Reactome:REACT_910, GO:0000075=Reactome:REACT_1538, GO:0005654=Reactome:REACT_9051, GO:0000278=Reactome:REACT_152, GO:0000090=Reactome:REACT_1275, GO:0051301=GO_REF:0000037} Q8NHZ8 Anaphase-promoting complex subunit CDC26 protein 20130415 {GO:0005515=IPI, GO:0007094=TAS, GO:0051437=TAS, GO:0051436=TAS, GO:0031145=TAS, GO:0051439=TAS, GO:0005829=TAS, GO:0070979=IDA, GO:0005680=IDA, GO:0000087=TAS, GO:0000075=TAS, GO:0005654=TAS, GO:0000278=TAS, GO:0000090=TAS, GO:0051301=IEA} M phase of mitotic cell cycle, anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process, cell cycle checkpoint, cell division, mitotic anaphase, mitotic cell cycle, mitotic spindle assembly checkpoint, negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle, positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle, protein K11-linked ubiquitination, regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle anaphase-promoting complex, cytosol, nucleoplasm protein binding Human UniProtKB:Q13042 CDC27 HPA UniProtKB {GO:0005515=PMID:22014574, GO:0007094=Reactome:REACT_2137, GO:0005813=PMID:7736578, GO:0008283=PMID:7736578, GO:0019903=PMID:21241890, GO:0051437=Reactome:REACT_6904, GO:0005730=GO_REF:0000052, GO:0005819=PMID:7736578, GO:0005634=GO_REF:0000052, GO:0051436=Reactome:REACT_6785, GO:0031145=Reactome:REACT_6871, GO:0051439=Reactome:REACT_6867, GO:0005829=Reactome:REACT_9035, GO:0005737=GO_REF:0000054, GO:0070979=PMID:18485873, GO:0005680=PMID:21926987, GO:0000087=Reactome:REACT_910, GO:0000075=Reactome:REACT_1538, GO:0005654=Reactome:REACT_9051, GO:0005876=PMID:7736578, GO:0000278=Reactome:REACT_152, GO:0000090=Reactome:REACT_1275, GO:0007091=PMID:7736578, GO:0051301=GO_REF:0000038} P30260 Cell division cycle protein 27 homolog protein 20101115 {GO:0005515=IPI, GO:0007094=TAS, GO:0005813=IDA, GO:0008283=TAS, GO:0019903=IPI, GO:0051437=TAS, GO:0005730=IDA, GO:0005819=TAS, GO:0005634=IDA, GO:0051436=TAS, GO:0031145=TAS, GO:0051439=TAS, GO:0005829=TAS, GO:0005737=IDA, GO:0070979=IDA, GO:0005680=IDA, GO:0000087=TAS, GO:0000075=TAS, GO:0005654=TAS, GO:0005876=IDA, GO:0000278=TAS, GO:0000090=TAS, GO:0007091=IMP, GO:0051301=IEA} M phase of mitotic cell cycle, anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process, cell cycle checkpoint, cell division, cell proliferation, metaphase/anaphase transition of mitotic cell cycle, mitotic anaphase, mitotic cell cycle, mitotic spindle assembly checkpoint, negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle, positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle, protein K11-linked ubiquitination, regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle anaphase-promoting complex, centrosome, cytoplasm, cytosol, nucleolus, nucleoplasm, nucleus, spindle, spindle microtubule protein binding, protein phosphatase binding NOT Human CDC34 HPA UniProtKB {GO:0005515=PMID:19945379, GO:0000209=PMID:20347421, GO:0004842=PMID:20347421, GO:0016567=PMID:10373550, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0005524=GO_REF:0000037, GO:0005737=GO_REF:0000052, GO:0000082=PMID:8248134, GO:0006270=PMID:8248134, GO:0043161=PMID:20347421, GO:0070936=PMID:20061386, GO:0006464=PMID:8248134, GO:0043951=PMID:10373550} P49427 Ubiquitin-conjugating enzyme E2 R1 protein 20101115 {GO:0005515=IPI, GO:0000209=IDA, GO:0004842=IDA, GO:0016567=IDA, GO:0005730=IDA, GO:0005634=IDA, GO:0005524=IEA, GO:0005737=IDA, GO:0000082=NAS, GO:0006270=NAS, GO:0043161=IDA, GO:0070936=IDA, GO:0006464=NAS, GO:0043951=IDA} DNA replication initiation, G1/S transition of mitotic cell cycle, cellular protein modification process, negative regulation of cAMP-mediated signaling, proteasomal ubiquitin-dependent protein catabolic process, protein K48-linked ubiquitination, protein polyubiquitination, protein ubiquitination cytoplasm, nucleolus, nucleus ATP binding, protein binding, ubiquitin-protein ligase activity Human CDC37 HPA UniProtKB {GO:0005515=PMID:22939624, GO:0019901=GO_REF:0000002, GO:0051087=GO_REF:0000019, GO:0051879=GO_REF:0000019, GO:0031435=GO_REF:0000019, GO:0032587=GO_REF:0000019, GO:0000079=PMID:8666233, GO:0006605=PMID:8666233, GO:0043422=GO_REF:0000019, GO:0005829=Reactome:REACT_116154, GO:0060334=PMID:16280321, GO:0043234=GO_REF:0000019, GO:0005737=GO_REF:0000052, GO:0060338=PMID:16280321, GO:0031072=PMID:9660753, GO:0051082=PMID:8666233} Q16543 Hsp90 co-chaperone Cdc37 protein 20120912 {GO:0005515=IPI, GO:0019901=IEA, GO:0051087=IEA, GO:0051879=IEA, GO:0031435=IEA, GO:0032587=IEA, GO:0000079=TAS, GO:0006605=TAS, GO:0043422=IEA, GO:0005829=TAS, GO:0060334=IMP, GO:0043234=IEA, GO:0005737=IDA, GO:0060338=IMP, GO:0031072=IPI, GO:0051082=TAS} protein targeting, regulation of cyclin-dependent protein serine/threonine kinase activity, regulation of interferon-gamma-mediated signaling pathway, regulation of type I interferon-mediated signaling pathway cytoplasm, cytosol, protein complex, ruffle membrane Hsp90 protein binding, chaperone binding, heat shock protein binding, mitogen-activated protein kinase kinase kinase binding, protein binding, protein kinase B binding, protein kinase binding, unfolded protein binding Human CDC37L1 UniProtKB UniProtKB {GO:0005737=GO_REF:0000039} Q7L3B6 Hsp90 co-chaperone Cdc37-like 1 protein 20130413 {GO:0005737=IEA} cytoplasm Human UniProtKB-SubCell:SL-0086 CDC40 Reactome UniProtKB {GO:0008380=Reactome:REACT_1735, GO:0010467=Reactome:REACT_71, GO:0006369=Reactome:REACT_894, GO:0006406=Reactome:REACT_1597, GO:0006366=Reactome:REACT_1366, GO:0000398=Reactome:REACT_467, GO:0031124=Reactome:REACT_1849, GO:0005654=Reactome:REACT_1935, GO:0005681=PMID:9524131, GO:0071013=PMID:11991638} O60508 Pre-mRNA-processing factor 17 protein 20130213 {GO:0008380=TAS, GO:0010467=TAS, GO:0006369=TAS, GO:0006406=TAS, GO:0006366=TAS, GO:0000398=TAS, GO:0031124=TAS, GO:0005654=TAS, GO:0005681=TAS, GO:0071013=IDA} RNA splicing, gene expression, mRNA 3'-end processing, mRNA export from nucleus, mRNA splicing, via spliceosome, termination of RNA polymerase II transcription, transcription from RNA polymerase II promoter catalytic step 2 spliceosome, nucleoplasm, spliceosomal complex Human CDC42 ENSEMBL UniProtKB {GO:0045859=GO_REF:0000019, GO:0005515=PMID:10051605, GO:0072686=PMID:15642749, GO:0043497=GO_REF:0000019, GO:0060047=GO_REF:0000019, GO:0031424=GO_REF:0000019, GO:0046330=GO_REF:0000019, GO:0035088=GO_REF:0000019, GO:0072384=GO_REF:0000019, GO:0042995=GO_REF:0000019, GO:0051683=GO_REF:0000019, GO:0042802=PMID:9748241, GO:0031069=GO_REF:0000019, GO:0042692=Reactome:REACT_21303, GO:0005622=GO_REF:0000002, GO:0051489=PMID:14978216, GO:0043525=GO_REF:0000019, GO:0007173=Reactome:REACT_9417, GO:0043552=GO_REF:0000019, GO:0007411=Reactome:REACT_18266, GO:0007030=GO_REF:0000019, GO:0043025=PMID:21048939, GO:0031274=PMID:11035016, GO:0046847=GO_REF:0000019, GO:0051017=GO_REF:0000019, GO:0060684=GO_REF:0000019, GO:0007088=GO_REF:0000019, GO:0019901=PMID:21048939, GO:0005815=GO_REF:0000039, GO:0045740=GO_REF:0000019, GO:0042059=Reactome:REACT_12484, GO:0030496=PMID:15642749, GO:0031435=GO_REF:0000019, GO:0090316=GO_REF:0000019, GO:0006184=PMID:11035016, GO:0030742=GO_REF:0000019, GO:0051149=Reactome:REACT_21402, GO:0048554=GO_REF:0000019, GO:0045087=Reactome:REACT_6802, GO:0051835=GO_REF:0000019, GO:0038096=Reactome:REACT_160123, GO:0034332=GO_REF:0000019, GO:0043005=PMID:21048939, GO:0030036=PMID:11035016, GO:0003161=GO_REF:0000019, GO:0005886=GO_REF:0000019, GO:0007264=GO_REF:0000002, GO:0007097=GO_REF:0000019, GO:0031295=Reactome:REACT_19344, GO:0003924=PMID:11035016, GO:0031996=PMID:12612085, GO:0002040=GO_REF:0000019, GO:0030175=PMID:11035016, GO:0051233=PMID:15642749, GO:0003334=GO_REF:0000019, GO:0005829=Reactome:REACT_160291, GO:0005737=PMID:11260256, GO:0033138=GO_REF:0000019, GO:0031647=GO_REF:0000019, GO:0034191=PMID:16443932, GO:0035264=GO_REF:0000019, GO:0031333=PMID:11584266, GO:0071338=GO_REF:0000019, GO:0060661=GO_REF:0000019, GO:0030225=PMID:11260256, GO:0030141=GO_REF:0000019, GO:0060070=GO_REF:0000019, GO:0090136=GO_REF:0000019, GO:0051056=Reactome:REACT_11051, GO:0090135=GO_REF:0000019, GO:0042176=GO_REF:0000019, GO:0051988=PMID:15642749, GO:0048664=GO_REF:0000019, GO:0045177=GO_REF:0000019, GO:0060789=GO_REF:0000019, GO:0005525=GO_REF:0000019, GO:0010628=GO_REF:0000019, GO:0007163=PMID:11260256, GO:0000139=GO_REF:0000019, GO:0016020=GO_REF:0000038, GO:0007596=Reactome:REACT_604, GO:0010629=GO_REF:0000019, GO:0034613=GO_REF:0000019} Q5JYX0 Cell division control protein 42 homolog protein 20130413 {GO:0045859=IEA, GO:0005515=IPI, GO:0072686=IDA, GO:0043497=IEA, GO:0060047=IEA, GO:0031424=IEA, GO:0046330=IEA, GO:0035088=IEA, GO:0072384=IEA, GO:0042995=IEA, GO:0051683=IEA, GO:0042802=IPI, GO:0031069=IEA, GO:0042692=TAS, GO:0005622=IEA, GO:0051489=IDA, GO:0043525=IEA, GO:0007173=TAS, GO:0043552=IEA, GO:0007411=TAS, GO:0007030=IEA, GO:0043025=IDA, GO:0031274=IDA, GO:0046847=IEA, GO:0051017=IEA, GO:0060684=IEA, GO:0007088=IEA, GO:0019901=IPI, GO:0005815=IEA, GO:0045740=IEA, GO:0042059=TAS, GO:0030496=IDA, GO:0031435=IEA, GO:0090316=IEA, GO:0006184=TAS, GO:0030742=IEA, GO:0051149=TAS, GO:0048554=IEA, GO:0045087=TAS, GO:0051835=IEA, GO:0038096=TAS, GO:0034332=IEA, GO:0043005=IDA, GO:0030036=IDA, GO:0003161=IEA, GO:0005886=IEA, GO:0007264=IEA, GO:0007097=IEA, GO:0031295=TAS, GO:0003924=TAS, GO:0031996=IPI, GO:0002040=IEA, GO:0030175=IDA, GO:0051233=IDA, GO:0003334=IEA, GO:0005829=TAS, GO:0005737=IDA, GO:0033138=IEA, GO:0031647=IEA, GO:0034191=IPI, GO:0035264=IEA, GO:0031333=IPI, GO:0071338=IEA, GO:0060661=IEA, GO:0030225=TAS, GO:0030141=IEA, GO:0060070=IEA, GO:0090136=IEA, GO:0051056=TAS, GO:0090135=IEA, GO:0042176=IEA, GO:0051988=IMP, GO:0048664=IEA, GO:0045177=IEA, GO:0060789=IEA, GO:0005525=IEA, GO:0010628=IEA, GO:0007163=TAS, GO:0000139=IEA, GO:0016020=IEA, GO:0007596=TAS, GO:0010629=IEA, GO:0034613=IEA} Fc-gamma receptor signaling pathway involved in phagocytosis, GTP catabolic process, Golgi organization, T cell costimulation, actin cytoskeleton organization, actin filament branching, actin filament bundle assembly, adherens junction organization, axon guidance, blood coagulation, canonical Wnt receptor signaling pathway, cardiac conduction system development, cellular protein localization, epidermal growth factor receptor signaling pathway, epithelial cell-cell adhesion, epithelial-mesenchymal cell signaling, establishment of Golgi localization, establishment or maintenance of apical/basal cell polarity, establishment or maintenance of cell polarity, filopodium assembly, hair follicle morphogenesis, hair follicle placode formation, heart contraction, innate immune response, keratinization, keratinocyte development, macrophage differentiation, multicellular organism growth, muscle cell differentiation, negative regulation of epidermal growth factor receptor signaling pathway, negative regulation of gene expression, negative regulation of protein complex assembly, neuron fate determination, nuclear migration, organelle transport along microtubule, positive regulation of DNA replication, positive regulation of JNK cascade, positive regulation of gene expression, positive regulation of hair follicle cell proliferation, positive regulation of intracellular protein transport, positive regulation of metalloenzyme activity, positive regulation of muscle cell differentiation, positive regulation of neuron apoptotic process, positive regulation of peptidyl-serine phosphorylation, positive regulation of phosphatidylinositol 3-kinase activity, positive regulation of pseudopodium assembly, positive regulation of synapse structural plasticity, regulation of attachment of spindle microtubules to kinetochore, regulation of filopodium assembly, regulation of mitosis, regulation of protein catabolic process, regulation of protein heterodimerization activity, regulation of protein kinase activity, regulation of protein stability, regulation of small GTPase mediated signal transduction, small GTPase mediated signal transduction, sprouting angiogenesis, submandibular salivary gland formation Golgi membrane, apical part of cell, cell projection, cytoplasm, cytosol, filopodium, intracellular, membrane, microtubule organizing center, midbody, mitotic spindle, neuron projection, neuronal cell body, plasma membrane, secretory granule, spindle midzone GTP binding, GTP-dependent protein binding, GTPase activity, apolipoprotein A-I receptor binding, identical protein binding, mitogen-activated protein kinase kinase kinase binding, protein binding, protein kinase binding, thioesterase binding Human Ensembl:ENSRNOP00000030928 CDC42BPA IntAct UniProtKB {GO:0000287=PMID:9092543, GO:0042641=PMID:18854160, GO:0031532=PMID:9418861, GO:0007097=GO_REF:0000019, GO:0031032=PMID:18854160, GO:0000226=GO_REF:0000019, GO:0005524=PMID:9092543, GO:0046872=GO_REF:0000038, GO:0042802=PMID:11283256, GO:0035556=GO_REF:0000002, GO:0005083=GO_REF:0000002, GO:0005737=GO_REF:0000039, GO:0005543=GO_REF:0000002, GO:0016477=PMID:18854160, GO:0004674=PMID:21457715, GO:0005911=GO_REF:0000024, GO:0006468=PMID:9092543, GO:0031252=GO_REF:0000024} Q5VT25 Serine/threonine-protein kinase MRCK alpha protein 20130415 {GO:0000287=IDA, GO:0042641=IDA, GO:0031532=IDA, GO:0007097=IEA, GO:0031032=IMP, GO:0000226=IEA, GO:0005524=IDA, GO:0046872=IEA, GO:0042802=IPI, GO:0035556=IEA, GO:0005083=IEA, GO:0005737=IEA, GO:0005543=IEA, GO:0016477=IMP, GO:0004674=IDA, GO:0005911=ISS, GO:0006468=IDA, GO:0031252=ISS} actin cytoskeleton reorganization, actomyosin structure organization, cell migration, intracellular signal transduction, microtubule cytoskeleton organization, nuclear migration, protein phosphorylation actomyosin, cell leading edge, cell-cell junction, cytoplasm ATP binding, identical protein binding, magnesium ion binding, metal ion binding, phospholipid binding, protein serine/threonine kinase activity, small GTPase regulator activity Human UniProtKB:Q5VT25 CDC42BPB PINC UniProtKB {GO:0000287=GO_REF:0000024, GO:0042641=PMID:18854160, GO:0031532=GO_REF:0000024, GO:0005886=GO_REF:0000039, GO:0031032=PMID:18854160, GO:0005524=GO_REF:0000024, GO:0046872=GO_REF:0000038, GO:0035556=GO_REF:0000002, GO:0007165=PMID:9418861, GO:0005083=GO_REF:0000002, GO:0005737=GO_REF:0000039, GO:0004672=PMID:21949762, GO:0005543=GO_REF:0000002, GO:0007163=PMID:9418861, GO:0016477=PMID:18854160, GO:0005911=GO_REF:0000024, GO:0004674=GO_REF:0000024, GO:0007010=PMID:9418861, GO:0017048=GO_REF:0000019, GO:0006468=PMID:21949762, GO:0005856=PMID:9418861, GO:0031252=GO_REF:0000024} Q9Y5S2 Serine/threonine-protein kinase MRCK beta protein 20030904 {GO:0000287=ISS, GO:0042641=IDA, GO:0031532=ISS, GO:0005886=IEA, GO:0031032=IMP, GO:0005524=ISS, GO:0046872=IEA, GO:0035556=IEA, GO:0007165=TAS, GO:0005083=IEA, GO:0005737=IEA, GO:0004672=IDA, GO:0005543=IEA, GO:0007163=TAS, GO:0016477=IMP, GO:0005911=ISS, GO:0004674=ISS, GO:0007010=TAS, GO:0017048=IEA, GO:0006468=IDA, GO:0005856=TAS, GO:0031252=ISS} actin cytoskeleton reorganization, actomyosin structure organization, cell migration, cytoskeleton organization, establishment or maintenance of cell polarity, intracellular signal transduction, protein phosphorylation, signal transduction actomyosin, cell leading edge, cell-cell junction, cytoplasm, cytoskeleton, plasma membrane ATP binding, Rho GTPase binding, magnesium ion binding, metal ion binding, phospholipid binding, protein kinase activity, protein serine/threonine kinase activity, small GTPase regulator activity Human CDC42BPG HPA UniProtKB {GO:0005515=PMID:21903422, GO:0035556=GO_REF:0000002, GO:0005813=GO_REF:0000052, GO:0005737=GO_REF:0000039, GO:0005083=GO_REF:0000002, GO:0000287=PMID:15194684, GO:0005543=GO_REF:0000002, GO:0031532=GO_REF:0000024, GO:0004674=PMID:15194684, GO:0006468=PMID:15194684, GO:0031252=PMID:15194684, GO:0005524=PMID:15194684} Q6DT37 Serine/threonine-protein kinase MRCK gamma protein 20100326 {GO:0005515=IPI, GO:0035556=IEA, GO:0005813=IDA, GO:0005737=IEA, GO:0005083=IEA, GO:0000287=IDA, GO:0005543=IEA, GO:0031532=ISS, GO:0004674=IDA, GO:0006468=IDA, GO:0031252=IDA, GO:0005524=IDA} actin cytoskeleton reorganization, intracellular signal transduction, protein phosphorylation cell leading edge, centrosome, cytoplasm ATP binding, magnesium ion binding, phospholipid binding, protein binding, protein serine/threonine kinase activity, small GTPase regulator activity Human CDC42EP1 HPA UniProtKB {GO:0005515=PMID:21988832, GO:0005737=GO_REF:0000052, GO:0005794=GO_REF:0000052, GO:0005886=GO_REF:0000052, GO:0008360=PMID:11035016, GO:0031274=PMID:11035016, GO:0007266=GO_REF:0000019, GO:0015629=GO_REF:0000052, GO:0012505=GO_REF:0000039} Q00587 Cdc42 effector protein 1 protein 20080205 {GO:0005515=IPI, GO:0005737=IDA, GO:0005794=IDA, GO:0005886=IDA, GO:0008360=IDA, GO:0031274=IDA, GO:0007266=IEA, GO:0015629=IDA, GO:0012505=IEA} Rho protein signal transduction, positive regulation of pseudopodium assembly, regulation of cell shape Golgi apparatus, actin cytoskeleton, cytoplasm, endomembrane system, plasma membrane protein binding Human CDC42EP2 GOC UniProtKB {GO:0005515=PMID:11584266, GO:0030036=PMID:10430899, GO:0005886=PMID:10430899, GO:0008360=PMID:11035016, GO:0005100=PMID:10430899, GO:0012505=GO_REF:0000039, GO:0005737=GO_REF:0000052, GO:0031334=PMID:11584266, GO:0030838=PMID:11035016, GO:0016020=PMID:11035016, GO:0032321=PMID:10430899, GO:0001515=GO_REF:0000019, GO:0015630=GO_REF:0000052, GO:0031274=PMID:11035016, GO:0007015=PMID:11035016, GO:0017049=PMID:11035016} O14613 Cdc42 effector protein 2 protein 20130413 {GO:0005515=IPI, GO:0030036=IDA, GO:0005886=IDA, GO:0008360=IDA, GO:0005100=IMP, GO:0012505=IEA, GO:0005737=IDA, GO:0031334=TAS, GO:0030838=IDA, GO:0016020=IDA, GO:0032321=IMP, GO:0001515=IEA, GO:0015630=IDA, GO:0031274=IDA, GO:0007015=NAS, GO:0017049=IPI} actin cytoskeleton organization, actin filament organization, positive regulation of Rho GTPase activity, positive regulation of actin filament polymerization, positive regulation of protein complex assembly, positive regulation of pseudopodium assembly, regulation of cell shape cytoplasm, endomembrane system, membrane, microtubule cytoskeleton, plasma membrane GTP-Rho binding, Rho GTPase activator activity, opioid peptide activity, protein binding Human CDC42EP3 LIFEdb UniProtKB {GO:0007165=PMID:11035016, GO:0005737=GO_REF:0000037, GO:0005519=PMID:11035016, GO:0016020=GO_REF:0000037, GO:0008360=GO_REF:0000037, GO:0015629=GO_REF:0000054, GO:0012505=GO_REF:0000039} Q9UKI2 Cdc42 effector protein 3 protein 20100607 {GO:0007165=TAS, GO:0005737=IEA, GO:0005519=TAS, GO:0016020=IEA, GO:0008360=IEA, GO:0015629=IDA, GO:0012505=IEA} regulation of cell shape, signal transduction actin cytoskeleton, cytoplasm, endomembrane system, membrane cytoskeletal regulatory protein binding Human CDC42EP4 HPA UniProtKB {GO:0005737=GO_REF:0000019, GO:0016020=GO_REF:0000037, GO:0008360=PMID:11035016, GO:0015630=GO_REF:0000052, GO:0031274=PMID:11035016, GO:0017049=PMID:11035016, GO:0007266=GO_REF:0000019, GO:0015629=GO_REF:0000052, GO:0012505=GO_REF:0000039} Q9H3Q1 Cdc42 effector protein 4 protein 20100326 {GO:0005737=IEA, GO:0016020=IEA, GO:0008360=IDA, GO:0015630=IDA, GO:0031274=IDA, GO:0017049=NAS, GO:0007266=IEA, GO:0015629=IDA, GO:0012505=IEA} Rho protein signal transduction, positive regulation of pseudopodium assembly, regulation of cell shape actin cytoskeleton, cytoplasm, endomembrane system, membrane, microtubule cytoskeleton GTP-Rho binding Human CDC42EP5 UniProtKB UniProtKB {GO:0005737=PMID:11035016, GO:0016020=PMID:11035016, GO:0030838=PMID:11035016, GO:0005886=GO_REF:0000019, GO:0008360=PMID:11035016, GO:0007254=GO_REF:0000019, GO:0031274=PMID:11035016, GO:0017049=PMID:11035016, GO:0007266=GO_REF:0000019, GO:0005856=GO_REF:0000039, GO:0012505=GO_REF:0000039} Q6NZY7 Cdc42 effector protein 5 protein 20050923 {GO:0005737=IDA, GO:0016020=IDA, GO:0030838=IDA, GO:0005886=IEA, GO:0008360=IDA, GO:0007254=IEA, GO:0031274=IDA, GO:0017049=IPI, GO:0007266=IEA, GO:0005856=IEA, GO:0012505=IEA} JNK cascade, Rho protein signal transduction, positive regulation of actin filament polymerization, positive regulation of pseudopodium assembly, regulation of cell shape cytoplasm, cytoskeleton, endomembrane system, membrane, plasma membrane GTP-Rho binding Human CDC42SE1 HPA UniProtKB {GO:0005739=GO_REF:0000052, GO:0006909=GO_REF:0000037, GO:0007165=PMID:10816584, GO:0005737=GO_REF:0000052, GO:0005886=GO_REF:0000039, GO:0008360=GO_REF:0000037, GO:0005095=PMID:10816584, GO:0005856=GO_REF:0000039} Q9NRR8 CDC42 small effector protein 1 protein 20111111 {GO:0005739=IDA, GO:0006909=IEA, GO:0007165=TAS, GO:0005737=IDA, GO:0005886=IEA, GO:0008360=IEA, GO:0005095=TAS, GO:0005856=IEA} phagocytosis, regulation of cell shape, signal transduction cytoplasm, cytoskeleton, mitochondrion, plasma membrane GTPase inhibitor activity Human CDC42SE2 HPA UniProtKB {GO:0006909=GO_REF:0000037, GO:0005515=PMID:10816584, GO:0005886=GO_REF:0000052, GO:0008360=GO_REF:0000037, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0001891=GO_REF:0000039, GO:0042995=GO_REF:0000037, GO:0009966=PMID:10816584, GO:0043231=GO_REF:0000052, GO:0005737=GO_REF:0000037, GO:0005198=PMID:10816584, GO:0005856=GO_REF:0000039} Q9NRR3 CDC42 small effector protein 2 protein 20110516 {GO:0006909=IEA, GO:0005515=IPI, GO:0005886=IDA, GO:0008360=IEA, GO:0005730=IDA, GO:0005634=IDA, GO:0001891=IEA, GO:0042995=IEA, GO:0009966=IDA, GO:0043231=IDA, GO:0005737=IEA, GO:0005198=IDA, GO:0005856=IEA} phagocytosis, regulation of cell shape, regulation of signal transduction cell projection, cytoplasm, cytoskeleton, intracellular membrane-bounded organelle, nucleolus, nucleus, phagocytic cup, plasma membrane protein binding, structural molecule activity Human CDC45 HPA UniProtKB {GO:0005515=PMID:17887956, GO:0005813=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0000084=Reactome:REACT_899, GO:0006260=Reactome:REACT_6769, GO:0006271=Reactome:REACT_932, GO:0005737=GO_REF:0000039, GO:0000082=Reactome:REACT_1783, GO:0000083=Reactome:REACT_683, GO:0006270=GO_REF:0000002, GO:0000076=PMID:9660782, GO:0000075=Reactome:REACT_1538, GO:0005654=Reactome:REACT_22145, GO:0000278=Reactome:REACT_152} O75419 Cell division control protein 45 homolog protein 20101115 {GO:0005515=IPI, GO:0005813=IDA, GO:0005634=IDA, GO:0000084=TAS, GO:0006260=TAS, GO:0006271=TAS, GO:0005737=IEA, GO:0000082=TAS, GO:0000083=TAS, GO:0006270=IEA, GO:0000076=TAS, GO:0000075=TAS, GO:0005654=TAS, GO:0000278=TAS} DNA replication, DNA replication checkpoint, DNA replication initiation, DNA strand elongation involved in DNA replication, G1/S transition of mitotic cell cycle, S phase of mitotic cell cycle, cell cycle checkpoint, mitotic cell cycle, regulation of transcription involved in G1/S phase of mitotic cell cycle centrosome, cytoplasm, nucleoplasm, nucleus protein binding Human CDC5L HPA UniProtKB {GO:0005515=PMID:20176811, GO:0000974=PMID:20176811, GO:0006355=GO_REF:0000029, GO:0003723=GO_REF:0000019, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0071013=PMID:11991638, GO:0003677=PMID:8917598, GO:0006351=GO_REF:0000037, GO:0007049=GO_REF:0000037, GO:0005737=GO_REF:0000039, GO:0016607=PMID:16332694, GO:0000398=PMID:11991638, GO:0071987=PMID:20176811, GO:0003682=GO_REF:0000002} Q99459 Cell division cycle 5-like protein protein 20081203 {GO:0005515=IPI, GO:0000974=IDA, GO:0006355=NAS, GO:0003723=IEA, GO:0005730=IDA, GO:0005634=IDA, GO:0071013=IDA, GO:0003677=NAS, GO:0006351=IEA, GO:0007049=IEA, GO:0005737=IEA, GO:0016607=IDA, GO:0000398=IC, GO:0071987=IDA, GO:0003682=IEA} cell cycle, mRNA splicing, via spliceosome, regulation of transcription, DNA-dependent, transcription, DNA-dependent Prp19 complex, catalytic step 2 spliceosome, cytoplasm, nuclear speck, nucleolus, nucleus DNA binding, RNA binding, WD40-repeat domain binding, chromatin binding, protein binding NOT Human CDC6 BHF-UCL UniProtKB {GO:0005515=PMID:21041660, GO:0008285=PMID:9566895, GO:0005634=PMID:21041660, GO:0000079=PMID:9566895, GO:0051233=PMID:21041660, GO:0005829=Reactome:REACT_1673, GO:0000084=Reactome:REACT_899, GO:0000082=Reactome:REACT_1783, GO:0005737=PMID:9566895, GO:0000083=Reactome:REACT_683, GO:0000166=PMID:8990175, GO:0019900=PMID:21041660, GO:0017111=GO_REF:0000002, GO:0005819=GO_REF:0000019, GO:0051984=PMID:21041660, GO:0007089=PMID:9566895, GO:0005524=GO_REF:0000037, GO:0006260=Reactome:REACT_6769, GO:0007067=GO_REF:0000037, GO:0000922=PMID:21041660, GO:0003682=GO_REF:0000019, GO:0000076=PMID:9566895, GO:0000075=Reactome:REACT_1538, GO:0090007=PMID:21041660, GO:0005654=Reactome:REACT_111167, GO:0008156=PMID:9566895, GO:0000278=Reactome:REACT_152, GO:0051301=GO_REF:0000037} Q99741 Cell division control protein 6 homolog protein 20110202 {GO:0005515=IPI, GO:0008285=TAS, GO:0005634=IDA, GO:0000079=TAS, GO:0051233=IDA, GO:0005829=TAS, GO:0000084=TAS, GO:0000082=TAS, GO:0005737=TAS, GO:0000083=TAS, GO:0000166=TAS, GO:0019900=IPI, GO:0017111=IEA, GO:0005819=IEA, GO:0051984=IDA, GO:0007089=TAS, GO:0005524=IEA, GO:0006260=TAS, GO:0007067=IEA, GO:0000922=IDA, GO:0003682=IEA, GO:0000076=TAS, GO:0000075=TAS, GO:0090007=IMP, GO:0005654=TAS, GO:0008156=TAS, GO:0000278=TAS, GO:0051301=IEA} DNA replication, DNA replication checkpoint, G1/S transition of mitotic cell cycle, S phase of mitotic cell cycle, cell cycle checkpoint, cell division, mitosis, mitotic cell cycle, negative regulation of DNA replication, negative regulation of cell proliferation, positive regulation of chromosome segregation, regulation of cyclin-dependent protein serine/threonine kinase activity, regulation of mitotic anaphase, regulation of transcription involved in G1/S phase of mitotic cell cycle, traversing start control point of mitotic cell cycle cytoplasm, cytosol, nucleoplasm, nucleus, spindle, spindle midzone, spindle pole ATP binding, chromatin binding, kinase binding, nucleoside-triphosphatase activity, nucleotide binding, protein binding Human CDC7 Reactome UniProtKB {GO:0008284=PMID:17102137, GO:0033261=PMID:17102137, GO:0005634=PMID:9250678, GO:0005524=GO_REF:0000037, GO:0046872=GO_REF:0000037, GO:0006260=Reactome:REACT_6769, GO:0005737=PMID:9250678, GO:0000082=Reactome:REACT_1783, GO:0004672=GO_REF:0000002, GO:0004674=GO_REF:0000037, GO:0016301=PMID:9250678, GO:0000075=Reactome:REACT_1538, GO:0005654=Reactome:REACT_6750, GO:0000278=Reactome:REACT_152, GO:0051301=GO_REF:0000037} O00311 Cell division cycle 7-related protein kinase protein 20130213 {GO:0008284=IMP, GO:0033261=IMP, GO:0005634=IDA, GO:0005524=IEA, GO:0046872=IEA, GO:0006260=TAS, GO:0005737=IDA, GO:0000082=TAS, GO:0004672=IEA, GO:0004674=IEA, GO:0016301=IDA, GO:0000075=TAS, GO:0005654=TAS, GO:0000278=TAS, GO:0051301=IEA} DNA replication, G1/S transition of mitotic cell cycle, cell cycle checkpoint, cell division, mitotic cell cycle, positive regulation of cell proliferation, regulation of S phase cytoplasm, nucleoplasm, nucleus ATP binding, kinase activity, metal ion binding, protein kinase activity, protein serine/threonine kinase activity Human CDC73 IntAct UniProtKB {GO:0005515=PMID:20541477, GO:0006378=PMID:21329879, GO:0033523=PMID:16307923, GO:0008285=PMID:16989776, GO:0000993=PMID:15923622, GO:0050680=PMID:18987311, GO:0048147=PMID:18987311, GO:0030177=PMID:16630820, GO:0005634=PMID:15923622, GO:2000134=PMID:16989776, GO:0045749=PMID:15923622, GO:0001711=GO_REF:0000024, GO:0006351=GO_REF:0000037, GO:0007049=GO_REF:0000037, GO:0071222=GO_REF:0000024, GO:0045638=PMID:20541477, GO:0045944=PMID:20178742, GO:0019827=GO_REF:0000024, GO:0032968=PMID:20178742, GO:0016593=PMID:20178742, GO:0016055=GO_REF:0000037, GO:0010390=PMID:16307923, GO:0031442=PMID:19136632} Q6P1J9 Parafibromin protein 20130415 {GO:0005515=IPI, GO:0006378=IMP, GO:0033523=IDA, GO:0008285=IDA, GO:0000993=IDA, GO:0050680=IMP, GO:0048147=IMP, GO:0030177=IDA, GO:0005634=IDA, GO:2000134=IDA, GO:0045749=IMP, GO:0001711=ISS, GO:0006351=IEA, GO:0007049=IEA, GO:0071222=ISS, GO:0045638=IDA, GO:0045944=IDA, GO:0019827=ISS, GO:0032968=IDA, GO:0016593=IDA, GO:0016055=IEA, GO:0010390=IDA, GO:0031442=IMP} Wnt receptor signaling pathway, cell cycle, cellular response to lipopolysaccharide, endodermal cell fate commitment, histone H2B ubiquitination, histone monoubiquitination, mRNA polyadenylation, negative regulation of G1/S transition of mitotic cell cycle, negative regulation of S phase of mitotic cell cycle, negative regulation of cell proliferation, negative regulation of epithelial cell proliferation, negative regulation of fibroblast proliferation, negative regulation of myeloid cell differentiation, positive regulation of Wnt receptor signaling pathway, positive regulation of mRNA 3'-end processing, positive regulation of transcription elongation from RNA polymerase II promoter, positive regulation of transcription from RNA polymerase II promoter, stem cell maintenance, transcription, DNA-dependent Cdc73/Paf1 complex, nucleus RNA polymerase II core binding, protein binding Human UniProtKB:Q03164 CDCA2 HPA UniProtKB {GO:0007067=GO_REF:0000037, GO:0005737=GO_REF:0000052, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0051301=GO_REF:0000037} Q69YH5 Cell division cycle-associated protein 2 protein 20101115 {GO:0007067=IEA, GO:0005737=IDA, GO:0005730=IDA, GO:0005634=IDA, GO:0051301=IEA} cell division, mitosis cytoplasm, nucleolus, nucleus Human CDCA3 UniProtKB UniProtKB {GO:0008150=GO_REF:0000015, GO:0003674=GO_REF:0000015, GO:0007067=GO_REF:0000037, GO:0016567=GO_REF:0000041, GO:0005575=GO_REF:0000015, GO:0005829=GO_REF:0000039, GO:0051301=GO_REF:0000037} Q99618 Cell division cycle-associated protein 3 protein 20061026 {GO:0008150=ND, GO:0003674=ND, GO:0007067=IEA, GO:0016567=IEA, GO:0005575=ND, GO:0005829=IEA, GO:0051301=IEA} biological_process, cell division, mitosis, protein ubiquitination cellular_component, cytosol molecular_function Human CDCA4 UniProtKB UniProtKB {GO:0005634=GO_REF:0000039} Q9BXL8 Cell division cycle-associated protein 4 protein 20130413 {GO:0005634=IEA} nucleus Human UniProtKB-SubCell:SL-0191 CDCA5 HPA UniProtKB {GO:0005515=PMID:21111234, GO:0007076=PMID:15837422, GO:0000236=Reactome:REACT_682, GO:0000790=GO_REF:0000024, GO:0005886=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0071922=PMID:17349791, GO:0005829=Reactome:REACT_150267, GO:0006302=PMID:17349791, GO:0000084=Reactome:REACT_899, GO:0005737=GO_REF:0000024, GO:0000082=PMID:15837422, GO:0000087=Reactome:REACT_910, GO:0005694=Reactome:REACT_150454, GO:0005730=GO_REF:0000052, GO:0051329=GO_REF:0000024, GO:0007067=PMID:15837422, GO:0008278=PMID:17349791, GO:0003682=PMID:15837422, GO:0005654=Reactome:REACT_150445, GO:0007080=PMID:15837422, GO:0000278=Reactome:REACT_152, GO:0000090=Reactome:REACT_1275, GO:0000775=Reactome:REACT_150445, GO:0051301=GO_REF:0000037, GO:0007064=PMID:17349791} Q96FF9 Sororin protein 20101115 {GO:0005515=IPI, GO:0007076=IMP, GO:0000236=TAS, GO:0000790=ISS, GO:0005886=IDA, GO:0005634=IDA, GO:0071922=IMP, GO:0005829=TAS, GO:0006302=IMP, GO:0000084=TAS, GO:0005737=ISS, GO:0000082=IDA, GO:0000087=TAS, GO:0005694=TAS, GO:0005730=IDA, GO:0051329=ISS, GO:0007067=IDA, GO:0008278=IDA, GO:0003682=TAS, GO:0005654=TAS, GO:0007080=IMP, GO:0000278=TAS, GO:0000090=TAS, GO:0000775=TAS, GO:0051301=IEA, GO:0007064=IMP} G1/S transition of mitotic cell cycle, M phase of mitotic cell cycle, S phase of mitotic cell cycle, cell division, double-strand break repair, interphase of mitotic cell cycle, mitosis, mitotic anaphase, mitotic cell cycle, mitotic chromosome condensation, mitotic metaphase plate congression, mitotic prometaphase, mitotic sister chromatid cohesion, regulation of cohesin localization to chromatin chromosome, chromosome, centromeric region, cohesin complex, cytoplasm, cytosol, nuclear chromatin, nucleolus, nucleoplasm, nucleus, plasma membrane chromatin binding, protein binding Human CDCA7 MGI UniProtKB {GO:0006355=GO_REF:0000037, GO:0042127=PMID:11598121, GO:0005634=PMID:11598121, GO:0006351=GO_REF:0000037, GO:0051301=GO_REF:0000038} Q9BWT1 Cell division cycle-associated protein 7 protein 20060111 {GO:0006355=IEA, GO:0042127=IDA, GO:0005634=IDA, GO:0006351=IEA, GO:0051301=IEA} cell division, regulation of cell proliferation, regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus Human CDCA7L HPA UniProtKB {GO:0008284=PMID:15994933, GO:0006355=GO_REF:0000037, GO:0005737=GO_REF:0000052, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0006351=GO_REF:0000037} Q96GN5 Cell division cycle-associated 7-like protein protein 20101115 {GO:0008284=IDA, GO:0006355=IEA, GO:0005737=IDA, GO:0005730=IDA, GO:0005634=IDA, GO:0006351=IEA} positive regulation of cell proliferation, regulation of transcription, DNA-dependent, transcription, DNA-dependent cytoplasm, nucleolus, nucleus Human CDCA8 HPA UniProtKB {GO:0005515=PMID:18243099, GO:0000236=Reactome:REACT_682, GO:0051276=PMID:15260989, GO:0005825=GO_REF:0000052, GO:0010369=GO_REF:0000019, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0005829=Reactome:REACT_150414, GO:0043234=PMID:16239925, GO:0032133=PMID:18591255, GO:0000089=PMID:15260989, GO:0000087=Reactome:REACT_910, GO:0000278=Reactome:REACT_152, GO:0000090=Reactome:REACT_1275, GO:0000775=PMID:15260989, GO:0051301=GO_REF:0000037} Q53HL2 Borealin protein 20120912 {GO:0005515=IPI, GO:0000236=TAS, GO:0051276=IMP, GO:0005825=IDA, GO:0010369=IEA, GO:0005730=IDA, GO:0005634=IDA, GO:0005829=TAS, GO:0043234=IDA, GO:0032133=IPI, GO:0000089=IMP, GO:0000087=TAS, GO:0000278=TAS, GO:0000090=TAS, GO:0000775=IDA, GO:0051301=IEA} M phase of mitotic cell cycle, cell division, chromosome organization, mitotic anaphase, mitotic cell cycle, mitotic metaphase, mitotic prometaphase chromocenter, chromosome passenger complex, chromosome, centromeric region, cytosol, half bridge of spindle pole body, nucleolus, nucleus, protein complex protein binding Human CDCP1 UniProtKB UniProtKB {GO:0005886=GO_REF:0000039, GO:0005576=GO_REF:0000039, GO:0016021=GO_REF:0000037} Q9H5V8 CUB domain-containing protein 1 protein 20130413 {GO:0005886=IEA, GO:0005576=IEA, GO:0016021=IEA} extracellular region, integral to membrane, plasma membrane Human UniProtKB-SubCell:SL-0039 CDH1 HPA UniProtKB {GO:0005802=PMID:17620337, GO:0005515=PMID:20086044, GO:0030054=PMID:19038973, GO:0008013=PMID:17620337, GO:0007605=GO_REF:0000019, GO:0016342=PMID:18593713, GO:0042993=PMID:16338932, GO:0031175=GO_REF:0000019, GO:2000008=GO_REF:0000019, GO:0016337=PMID:16338932, GO:0070830=GO_REF:0000019, GO:0051260=GO_REF:0000019, GO:0050839=PMID:16338932, GO:0071285=PMID:12937339, GO:0022408=PMID:19653274, GO:0005794=GO_REF:0000039, GO:0009986=GO_REF:0000019, GO:0045295=PMID:1639850, GO:0019903=GO_REF:0000019, GO:0034329=Reactome:REACT_20676, GO:0005509=GO_REF:0000002, GO:0019904=GO_REF:0000019, GO:0030506=PMID:17620337, GO:0009636=GO_REF:0000019, GO:0007416=GO_REF:0000019, GO:0045216=Reactome:REACT_19331, GO:0043281=GO_REF:0000019, GO:0033561=GO_REF:0000019, GO:0050776=Reactome:REACT_11152, GO:0009898=PMID:20189993, GO:0045893=PMID:16338932, GO:0005925=GO_REF:0000052, GO:0019538=GO_REF:0000019, GO:0034332=Reactome:REACT_19195, GO:0048471=PMID:16338932, GO:0005886=GO_REF:0000052, GO:0060693=GO_REF:0000019, GO:0021983=GO_REF:0000019, GO:0015629=PMID:16338932, GO:0006921=Reactome:REACT_995, GO:0016323=GO_REF:0000019, GO:0043296=PMID:10460003, GO:0071681=PMID:10868478, GO:0005737=GO_REF:0000052, GO:0005913=PMID:20086044, GO:0071230=GO_REF:0000019, GO:0090102=GO_REF:0000019, GO:0043679=GO_REF:0000019, GO:0060662=GO_REF:0000019, GO:0007156=GO_REF:0000002, GO:0043220=GO_REF:0000019, GO:0016235=GO_REF:0000052, GO:0042493=GO_REF:0000019, GO:0045177=GO_REF:0000019, GO:0006915=Reactome:REACT_578, GO:0001829=GO_REF:0000019, GO:0072659=PMID:17620337, GO:0016328=PMID:17620337, GO:0032794=PMID:20116244, GO:0033268=GO_REF:0000019, GO:0016020=GO_REF:0000002, GO:0043219=GO_REF:0000019, GO:0016021=GO_REF:0000038, GO:0005768=GO_REF:0000039} Q9UII8 E-Cad/CTF3 protein 20080818 {GO:0005802=IMP, GO:0005515=IPI, GO:0030054=IDA, GO:0008013=IDA, GO:0007605=IEA, GO:0016342=IDA, GO:0042993=IDA, GO:0031175=IEA, GO:2000008=IEA, GO:0016337=IDA, GO:0070830=IEA, GO:0051260=IEA, GO:0050839=NAS, GO:0071285=IDA, GO:0022408=IMP, GO:0005794=IEA, GO:0009986=IEA, GO:0045295=IPI, GO:0019903=IEA, GO:0034329=TAS, GO:0005509=IEA, GO:0019904=IEA, GO:0030506=IPI, GO:0009636=IEA, GO:0007416=IEA, GO:0045216=TAS, GO:0043281=IEA, GO:0033561=IEA, GO:0050776=TAS, GO:0009898=IDA, GO:0045893=IDA, GO:0005925=IDA, GO:0019538=IEA, GO:0034332=TAS, GO:0048471=IDA, GO:0005886=IDA, GO:0060693=IEA, GO:0021983=IEA, GO:0015629=IDA, GO:0006921=TAS, GO:0016323=IEA, GO:0043296=IDA, GO:0071681=IDA, GO:0005737=IDA, GO:0005913=IDA, GO:0071230=IEA, GO:0090102=IEA, GO:0043679=IEA, GO:0060662=IEA, GO:0007156=IEA, GO:0043220=IEA, GO:0016235=IDA, GO:0042493=IEA, GO:0045177=IEA, GO:0006915=TAS, GO:0001829=IEA, GO:0072659=IDA, GO:0016328=IDA, GO:0032794=IPI, GO:0033268=IEA, GO:0016020=IEA, GO:0043219=IEA, GO:0016021=IEA, GO:0005768=IEA} adherens junction organization, apoptotic process, cell junction assembly, cell-cell adhesion, cell-cell junction organization, cellular component disassembly involved in execution phase of apoptosis, cellular response to amino acid stimulus, cellular response to indole-3-methanol, cellular response to lithium ion, cochlea development, homophilic cell adhesion, negative regulation of cell-cell adhesion, neuron projection development, pituitary gland development, positive regulation of transcription factor import into nucleus, positive regulation of transcription, DNA-dependent, protein homooligomerization, protein localization to plasma membrane, protein metabolic process, regulation of branching involved in salivary gland morphogenesis, regulation of cysteine-type endopeptidase activity involved in apoptotic process, regulation of immune response, regulation of protein localization to cell surface, regulation of water loss via skin, response to drug, response to toxic substance, salivary gland cavitation, sensory perception of sound, synapse assembly, tight junction assembly, trophectodermal cell differentiation Golgi apparatus, Schmidt-Lanterman incisure, actin cytoskeleton, aggresome, apical junction complex, apical part of cell, axon terminus, basolateral plasma membrane, catenin complex, cell junction, cell surface, cell-cell adherens junction, cytoplasm, endosome, focal adhesion, integral to membrane, internal side of plasma membrane, lateral loop, lateral plasma membrane, membrane, node of Ranvier, perinuclear region of cytoplasm, plasma membrane, trans-Golgi network GTPase activating protein binding, ankyrin binding, beta-catenin binding, calcium ion binding, cell adhesion molecule binding, gamma-catenin binding, protein binding, protein domain specific binding, protein phosphatase binding Human CDH10 Reactome UniProtKB {GO:0016337=PMID:10861224, GO:0005886=Reactome:REACT_19416, GO:0034329=Reactome:REACT_20676, GO:0005509=GO_REF:0000002, GO:0016021=GO_REF:0000029, GO:0007156=GO_REF:0000029, GO:0045216=Reactome:REACT_19331, GO:0034332=Reactome:REACT_19195} Q9Y6N8 Cadherin-10 protein 20130228 {GO:0016337=NAS, GO:0005886=TAS, GO:0034329=TAS, GO:0005509=IEA, GO:0016021=NAS, GO:0007156=NAS, GO:0045216=TAS, GO:0034332=TAS} adherens junction organization, cell junction assembly, cell-cell adhesion, cell-cell junction organization, homophilic cell adhesion integral to membrane, plasma membrane calcium ion binding Human CDH11 Reactome UniProtKB {GO:0001501=PMID:8163513, GO:0016337=GO_REF:0000029, GO:0001503=PMID:8163513, GO:0005886=Reactome:REACT_19416, GO:0034329=Reactome:REACT_20676, GO:0005509=GO_REF:0000002, GO:0016021=GO_REF:0000029, GO:0007155=PMID:8163513, GO:0007156=GO_REF:0000029, GO:0045216=Reactome:REACT_19331, GO:0034332=Reactome:REACT_19195} P55287 Cadherin-11 protein 20130228 {GO:0001501=TAS, GO:0016337=NAS, GO:0001503=NAS, GO:0005886=TAS, GO:0034329=TAS, GO:0005509=IEA, GO:0016021=NAS, GO:0007155=TAS, GO:0007156=NAS, GO:0045216=TAS, GO:0034332=TAS} adherens junction organization, cell adhesion, cell junction assembly, cell-cell adhesion, cell-cell junction organization, homophilic cell adhesion, ossification, skeletal system development integral to membrane, plasma membrane calcium ion binding Human CDH12 Reactome UniProtKB {GO:0016337=GO_REF:0000029, GO:0005886=Reactome:REACT_19416, GO:0034329=Reactome:REACT_20676, GO:0005509=GO_REF:0000002, GO:0016021=GO_REF:0000029, GO:0007156=GO_REF:0000029, GO:0045216=Reactome:REACT_19331, GO:0034332=Reactome:REACT_19195} P55289 Cadherin-12 protein 20130228 {GO:0016337=NAS, GO:0005886=TAS, GO:0034329=TAS, GO:0005509=IEA, GO:0016021=NAS, GO:0007156=NAS, GO:0045216=TAS, GO:0034332=TAS} adherens junction organization, cell junction assembly, cell-cell adhesion, cell-cell junction organization, homophilic cell adhesion integral to membrane, plasma membrane calcium ion binding Human CDH13 BHF-UCL UniProtKB {GO:0043005=PMID:10737605, GO:0008285=PMID:10737605, GO:0005886=PMID:10737605, GO:0030032=PMID:15703273, GO:0002040=PMID:16873731, GO:0031225=GO_REF:0000037, GO:0007266=PMID:15703273, GO:0005615=PMID:16873731, GO:0050850=PMID:16013438, GO:0050927=PMID:16013438, GO:0016339=PMID:10601632, GO:0005737=PMID:10737605, GO:0030100=PMID:17573778, GO:0045944=PMID:16099944, GO:0051668=PMID:17573778, GO:0007156=PMID:10601632, GO:0071813=PMID:11027617, GO:0030335=PMID:14729458, GO:0045296=PMID:10601632, GO:0034329=Reactome:REACT_20676, GO:0055100=GO_REF:0000024, GO:0005509=GO_REF:0000002, GO:0030169=PMID:16013438, GO:0043616=PMID:15816843, GO:0048661=PMID:15364621, GO:0045216=Reactome:REACT_19331, GO:0042058=PMID:17573778, GO:0016601=PMID:15703273, GO:0007162=PMID:14729458, GO:0055096=PMID:16013438, GO:0001938=PMID:15364621, GO:0043542=PMID:14729458, GO:0005901=PMID:9650591, GO:0001954=PMID:17573778, GO:0034332=Reactome:REACT_19195} P55290 Cadherin-13 protein 20071113 {GO:0043005=IDA, GO:0008285=IDA, GO:0005886=IDA, GO:0030032=IDA, GO:0002040=IDA, GO:0031225=IEA, GO:0007266=IMP, GO:0005615=IDA, GO:0050850=IDA, GO:0050927=IDA, GO:0016339=IDA, GO:0005737=IDA, GO:0030100=IMP, GO:0045944=IMP, GO:0051668=IMP, GO:0007156=IDA, GO:0071813=IDA, GO:0030335=IDA, GO:0045296=IDA, GO:0034329=TAS, GO:0055100=ISS, GO:0005509=IEA, GO:0030169=IDA, GO:0043616=IDA, GO:0048661=IMP, GO:0045216=TAS, GO:0042058=IMP, GO:0016601=IMP, GO:0007162=IDA, GO:0055096=IDA, GO:0001938=IMP, GO:0043542=IDA, GO:0005901=IDA, GO:0001954=IMP, GO:0034332=TAS} Rac protein signal transduction, Rho protein signal transduction, adherens junction organization, calcium-dependent cell-cell adhesion, cell junction assembly, cell-cell junction organization, endothelial cell migration, homophilic cell adhesion, keratinocyte proliferation, lamellipodium assembly, localization within membrane, low-density lipoprotein particle mediated signaling, negative regulation of cell adhesion, negative regulation of cell proliferation, positive regulation of calcium-mediated signaling, positive regulation of cell migration, positive regulation of cell-matrix adhesion, positive regulation of endothelial cell proliferation, positive regulation of positive chemotaxis, positive regulation of smooth muscle cell proliferation, positive regulation of transcription from RNA polymerase II promoter, regulation of endocytosis, regulation of epidermal growth factor receptor signaling pathway, sprouting angiogenesis anchored to membrane, caveola, cytoplasm, extracellular space, neuron projection, plasma membrane adiponectin binding, cadherin binding, calcium ion binding, lipoprotein particle binding, low-density lipoprotein particle binding Human CDH15 Reactome UniProtKB {GO:0042692=Reactome:REACT_21303, GO:0051149=Reactome:REACT_21402, GO:0031594=GO_REF:0000019, GO:0005886=Reactome:REACT_21371, GO:0034329=Reactome:REACT_20676, GO:0005901=GO_REF:0000019, GO:0005509=GO_REF:0000002, GO:0016021=GO_REF:0000037, GO:0007155=PMID:9545347, GO:0007156=GO_REF:0000002, GO:0045216=Reactome:REACT_19331, GO:0034332=Reactome:REACT_19195} P55291 Cadherin-15 protein 20130301 {GO:0042692=TAS, GO:0051149=TAS, GO:0031594=IEA, GO:0005886=TAS, GO:0034329=TAS, GO:0005901=IEA, GO:0005509=IEA, GO:0016021=IEA, GO:0007155=TAS, GO:0007156=IEA, GO:0045216=TAS, GO:0034332=TAS} adherens junction organization, cell adhesion, cell junction assembly, cell-cell junction organization, homophilic cell adhesion, muscle cell differentiation, positive regulation of muscle cell differentiation caveola, integral to membrane, neuromuscular junction, plasma membrane calcium ion binding Human CDH16 PINC UniProtKB {GO:0005886=GO_REF:0000039, GO:0005509=GO_REF:0000002, GO:0016021=GO_REF:0000037, GO:0007155=PMID:9721215, GO:0007156=GO_REF:0000002} O75309 Cadherin-16 protein 20030904 {GO:0005886=IEA, GO:0005509=IEA, GO:0016021=IEA, GO:0007155=TAS, GO:0007156=IEA} cell adhesion, homophilic cell adhesion integral to membrane, plasma membrane calcium ion binding Human CDH17 PINC UniProtKB {GO:0016339=GO_REF:0000019, GO:0005215=PMID:8153632, GO:0016323=GO_REF:0000019, GO:0005427=GO_REF:0000019, GO:0016020=GO_REF:0000002, GO:0005886=GO_REF:0000002, GO:0005509=GO_REF:0000002, GO:0006810=PMID:8153632, GO:0016021=GO_REF:0000037, GO:0007155=PMID:8153632, GO:0007156=GO_REF:0000019} Q12864 Cadherin-17 protein 20030904 {GO:0016339=IEA, GO:0005215=TAS, GO:0016323=IEA, GO:0005427=IEA, GO:0016020=IEA, GO:0005886=IEA, GO:0005509=IEA, GO:0006810=NAS, GO:0016021=IEA, GO:0007155=TAS, GO:0007156=IEA} calcium-dependent cell-cell adhesion, cell adhesion, homophilic cell adhesion, transport basolateral plasma membrane, integral to membrane, membrane, plasma membrane calcium ion binding, proton-dependent oligopeptide secondary active transmembrane transporter activity, transporter activity Human CDH18 Reactome UniProtKB {GO:0005886=Reactome:REACT_19416, GO:0034329=Reactome:REACT_20676, GO:0005509=GO_REF:0000002, GO:0016021=GO_REF:0000037, GO:0007156=GO_REF:0000002, GO:0045216=Reactome:REACT_19331, GO:0034332=Reactome:REACT_19195} Q13634 Cadherin-18 protein 20130228 {GO:0005886=TAS, GO:0034329=TAS, GO:0005509=IEA, GO:0016021=IEA, GO:0007156=IEA, GO:0045216=TAS, GO:0034332=TAS} adherens junction organization, cell junction assembly, cell-cell junction organization, homophilic cell adhesion integral to membrane, plasma membrane calcium ion binding Human CDH19 UniProtKB UniProtKB {GO:0016337=GO_REF:0000029, GO:0005886=GO_REF:0000039, GO:0005509=GO_REF:0000002, GO:0016021=GO_REF:0000029, GO:0007156=GO_REF:0000029} Q9H159 Cadherin-19 protein 20021106 {GO:0016337=NAS, GO:0005886=IEA, GO:0005509=IEA, GO:0016021=NAS, GO:0007156=NAS} cell-cell adhesion, homophilic cell adhesion integral to membrane, plasma membrane calcium ion binding Human CDH2 BHF-UCL UniProtKB {GO:0005886=Reactome:REACT_21371, GO:0008013=PMID:16344550, GO:0048514=GO_REF:0000019, GO:0016342=PMID:7650039, GO:0045202=GO_REF:0000019, GO:0016339=GO_REF:0000019, GO:0005916=GO_REF:0000019, GO:0042692=Reactome:REACT_21303, GO:0005913=PMID:19101069, GO:0005543=GO_REF:0000002, GO:0014704=GO_REF:0000024, GO:0005911=PMID:7650039, GO:0007155=PMID:2384753, GO:0007156=GO_REF:0000019, GO:0090090=GO_REF:0000019, GO:0007157=GO_REF:0000019, GO:0045295=PMID:7650039, GO:0045294=PMID:7650039, GO:0019903=GO_REF:0000019, GO:0034329=Reactome:REACT_20676, GO:0005509=GO_REF:0000002, GO:0030027=GO_REF:0000019, GO:0045216=Reactome:REACT_19331, GO:0051149=Reactome:REACT_21402, GO:0016477=GO_REF:0000019, GO:0016020=GO_REF:0000002, GO:0016021=GO_REF:0000037, GO:0043410=GO_REF:0000019, GO:0051146=GO_REF:0000019, GO:0034332=Reactome:REACT_19195} P19022 Cadherin-2 protein 20120521 {GO:0005886=TAS, GO:0008013=TAS, GO:0048514=IEA, GO:0016342=IDA, GO:0045202=IEA, GO:0016339=IEA, GO:0005916=IEA, GO:0042692=TAS, GO:0005913=IDA, GO:0005543=IEA, GO:0014704=ISS, GO:0005911=IDA, GO:0007155=TAS, GO:0007156=IEA, GO:0090090=IEA, GO:0007157=IEA, GO:0045295=IPI, GO:0045294=IPI, GO:0019903=IEA, GO:0034329=TAS, GO:0005509=IEA, GO:0030027=IEA, GO:0045216=TAS, GO:0051149=TAS, GO:0016477=IEA, GO:0016020=IEA, GO:0016021=IEA, GO:0043410=IEA, GO:0051146=IEA, GO:0034332=TAS} adherens junction organization, blood vessel morphogenesis, calcium-dependent cell-cell adhesion, cell adhesion, cell junction assembly, cell migration, cell-cell junction organization, heterophilic cell-cell adhesion, homophilic cell adhesion, muscle cell differentiation, negative regulation of canonical Wnt receptor signaling pathway, positive regulation of MAPK cascade, positive regulation of muscle cell differentiation, striated muscle cell differentiation catenin complex, cell-cell adherens junction, cell-cell junction, fascia adherens, integral to membrane, intercalated disc, lamellipodium, membrane, plasma membrane, synapse alpha-catenin binding, beta-catenin binding, calcium ion binding, gamma-catenin binding, phospholipid binding, protein phosphatase binding Human UniProtKB:P15116 CDH22 UniProtKB UniProtKB {GO:0005886=GO_REF:0000039, GO:0005509=GO_REF:0000002, GO:0016021=GO_REF:0000037, GO:0007156=GO_REF:0000002} Q9UJ99 Cadherin-22 protein 20130413 {GO:0005886=IEA, GO:0005509=IEA, GO:0016021=IEA, GO:0007156=IEA} homophilic cell adhesion integral to membrane, plasma membrane calcium ion binding Human UniProtKB-SubCell:SL-0039 CDH23 HGNC UniProtKB {GO:0005515=PMID:12485990, GO:0005886=GO_REF:0000039, GO:0007605=PMID:15537665, GO:0051480=PMID:17234811, GO:0005509=GO_REF:0000002, GO:0032420=PMID:12485990, GO:0045494=PMID:16679490, GO:0016339=PMID:11138009, GO:0016020=PMID:11138009, GO:0006816=PMID:17234811, GO:0050957=PMID:16679490, GO:0016021=GO_REF:0000037, GO:0007156=GO_REF:0000002, GO:0050896=GO_REF:0000037, GO:0050953=PMID:16679490} Q9H251 Cadherin-23 protein 20071018 {GO:0005515=IPI, GO:0005886=IEA, GO:0007605=IMP, GO:0051480=IMP, GO:0005509=IEA, GO:0032420=ISS, GO:0045494=IMP, GO:0016339=NAS, GO:0016020=NAS, GO:0006816=IMP, GO:0050957=IMP, GO:0016021=IEA, GO:0007156=IEA, GO:0050896=IEA, GO:0050953=IMP} calcium ion transport, calcium-dependent cell-cell adhesion, cytosolic calcium ion homeostasis, equilibrioception, homophilic cell adhesion, photoreceptor cell maintenance, response to stimulus, sensory perception of light stimulus, sensory perception of sound integral to membrane, membrane, plasma membrane, stereocilium calcium ion binding, protein binding Human CDH24 Reactome UniProtKB {GO:0016337=PMID:12734196, GO:0005886=Reactome:REACT_19416, GO:0005911=PMID:12734196, GO:0034329=Reactome:REACT_20676, GO:0005509=PMID:12734196, GO:0016021=GO_REF:0000037, GO:0007156=GO_REF:0000002, GO:0045216=Reactome:REACT_19331, GO:0034332=Reactome:REACT_19195} Q86UP0 Cadherin-24 protein 20130228 {GO:0016337=IDA, GO:0005886=TAS, GO:0005911=IDA, GO:0034329=TAS, GO:0005509=IDA, GO:0016021=IEA, GO:0007156=IEA, GO:0045216=TAS, GO:0034332=TAS} adherens junction organization, cell junction assembly, cell-cell adhesion, cell-cell junction organization, homophilic cell adhesion cell-cell junction, integral to membrane, plasma membrane calcium ion binding Human CDH3 Reactome UniProtKB {GO:0005913=GO_REF:0000019, GO:0016020=GO_REF:0000002, GO:0005886=Reactome:REACT_19416, GO:0034329=Reactome:REACT_20676, GO:0005509=GO_REF:0000002, GO:0016021=GO_REF:0000037, GO:0007155=PMID:2793940, GO:0007601=GO_REF:0000037, GO:0007156=GO_REF:0000002, GO:0045216=Reactome:REACT_19331, GO:0050896=GO_REF:0000037, GO:0034332=Reactome:REACT_19195} P22223 Cadherin-3 protein 20130228 {GO:0005913=IEA, GO:0016020=IEA, GO:0005886=TAS, GO:0034329=TAS, GO:0005509=IEA, GO:0016021=IEA, GO:0007155=TAS, GO:0007601=IEA, GO:0007156=IEA, GO:0045216=TAS, GO:0050896=IEA, GO:0034332=TAS} adherens junction organization, cell adhesion, cell junction assembly, cell-cell junction organization, homophilic cell adhesion, response to stimulus, visual perception cell-cell adherens junction, integral to membrane, membrane, plasma membrane calcium ion binding Human CDH4 HPA UniProtKB {GO:0005886=GO_REF:0000052, GO:0007411=GO_REF:0000019, GO:0005887=GO_REF:0000019, GO:0034329=Reactome:REACT_20676, GO:0005509=GO_REF:0000002, GO:0045773=GO_REF:0000019, GO:0007155=PMID:2059658, GO:0007156=GO_REF:0000019, GO:0045216=Reactome:REACT_19331, GO:0007157=GO_REF:0000019, GO:0034332=Reactome:REACT_19195} P55283 Cadherin-4 protein 20090616 {GO:0005886=IDA, GO:0007411=IEA, GO:0005887=IEA, GO:0034329=TAS, GO:0005509=IEA, GO:0045773=IEA, GO:0007155=TAS, GO:0007156=IEA, GO:0045216=TAS, GO:0007157=IEA, GO:0034332=TAS} adherens junction organization, axon guidance, cell adhesion, cell junction assembly, cell-cell junction organization, heterophilic cell-cell adhesion, homophilic cell adhesion, positive regulation of axon extension integral to plasma membrane, plasma membrane calcium ion binding Human CDH5 BHF-UCL UniProtKB {GO:0005515=PMID:20332120, GO:0008285=GO_REF:0000019, GO:0008013=PMID:18287330, GO:0005886=Reactome:REACT_19416, GO:0034329=Reactome:REACT_20676, GO:0019903=GO_REF:0000019, GO:0005509=GO_REF:0000002, GO:0005102=PMID:12088286, GO:2000114=PMID:20332120, GO:0045216=Reactome:REACT_19331, GO:0044325=PMID:19996314, GO:0071944=GO_REF:0000019, GO:0016020=PMID:9219219, GO:0005911=PMID:19996314, GO:0005923=GO_REF:0000019, GO:0016021=GO_REF:0000037, GO:0007156=GO_REF:0000002, GO:0001955=GO_REF:0000019, GO:0034332=Reactome:REACT_19195} P33151 Cadherin-5 protein 20100825 {GO:0005515=IPI, GO:0008285=IEA, GO:0008013=IPI, GO:0005886=TAS, GO:0034329=TAS, GO:0019903=IEA, GO:0005509=IEA, GO:0005102=IPI, GO:2000114=IMP, GO:0045216=TAS, GO:0044325=IPI, GO:0071944=IEA, GO:0016020=TAS, GO:0005911=IDA, GO:0005923=IEA, GO:0016021=IEA, GO:0007156=IEA, GO:0001955=IEA, GO:0034332=TAS} adherens junction organization, blood vessel maturation, cell junction assembly, cell-cell junction organization, homophilic cell adhesion, negative regulation of cell proliferation, regulation of establishment of cell polarity cell periphery, cell-cell junction, integral to membrane, membrane, plasma membrane, tight junction beta-catenin binding, calcium ion binding, ion channel binding, protein binding, protein phosphatase binding, receptor binding Human UniProtKB:Q9UBN4 CDH6 HPA UniProtKB {GO:0005737=GO_REF:0000052, GO:0005886=GO_REF:0000052, GO:0034329=Reactome:REACT_20676, GO:0005509=GO_REF:0000002, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0016021=GO_REF:0000037, GO:0007155=PMID:7743525, GO:0007156=GO_REF:0000002, GO:0045216=Reactome:REACT_19331, GO:0034332=Reactome:REACT_19195} P55285 Cadherin-6 protein 20101115 {GO:0005737=IDA, GO:0005886=IDA, GO:0034329=TAS, GO:0005509=IEA, GO:0005730=IDA, GO:0005634=IDA, GO:0016021=IEA, GO:0007155=TAS, GO:0007156=IEA, GO:0045216=TAS, GO:0034332=TAS} adherens junction organization, cell adhesion, cell junction assembly, cell-cell junction organization, homophilic cell adhesion cytoplasm, integral to membrane, nucleolus, nucleus, plasma membrane calcium ion binding Human CDH7 Reactome UniProtKB {GO:0016337=PMID:10861224, GO:0005886=Reactome:REACT_19416, GO:0034329=Reactome:REACT_20676, GO:0005509=GO_REF:0000002, GO:0016021=GO_REF:0000029, GO:0007156=GO_REF:0000029, GO:0045216=Reactome:REACT_19331, GO:0034332=Reactome:REACT_19195} Q9ULB5 Cadherin-7 protein 20130228 {GO:0016337=NAS, GO:0005886=TAS, GO:0034329=TAS, GO:0005509=IEA, GO:0016021=NAS, GO:0007156=NAS, GO:0045216=TAS, GO:0034332=TAS} adherens junction organization, cell junction assembly, cell-cell adhesion, cell-cell junction organization, homophilic cell adhesion integral to membrane, plasma membrane calcium ion binding Human CDH8 Reactome UniProtKB {GO:0005886=Reactome:REACT_19416, GO:0034329=Reactome:REACT_20676, GO:0009409=GO_REF:0000019, GO:0005509=GO_REF:0000002, GO:0035249=GO_REF:0000019, GO:0043679=GO_REF:0000019, GO:0043083=GO_REF:0000019, GO:0016021=GO_REF:0000037, GO:0007155=PMID:2059658, GO:0007156=GO_REF:0000002, GO:0045216=Reactome:REACT_19331, GO:0034332=Reactome:REACT_19195} P55286 Cadherin-8 protein 20130228 {GO:0005886=TAS, GO:0034329=TAS, GO:0009409=IEA, GO:0005509=IEA, GO:0035249=IEA, GO:0043679=IEA, GO:0043083=IEA, GO:0016021=IEA, GO:0007155=TAS, GO:0007156=IEA, GO:0045216=TAS, GO:0034332=TAS} adherens junction organization, cell adhesion, cell junction assembly, cell-cell junction organization, homophilic cell adhesion, response to cold, synaptic transmission, glutamatergic axon terminus, integral to membrane, plasma membrane, synaptic cleft calcium ion binding Human CDH9 Reactome UniProtKB {GO:0003674=GO_REF:0000015, GO:0016337=PMID:10861224, GO:0005886=Reactome:REACT_19416, GO:0034329=Reactome:REACT_20676, GO:0005509=GO_REF:0000002, GO:0016021=GO_REF:0000029, GO:0007156=GO_REF:0000029, GO:0045216=Reactome:REACT_19331, GO:0034332=Reactome:REACT_19195} Q9ULB4 Cadherin-9 protein 20130228 {GO:0003674=ND, GO:0016337=NAS, GO:0005886=TAS, GO:0034329=TAS, GO:0005509=IEA, GO:0016021=NAS, GO:0007156=NAS, GO:0045216=TAS, GO:0034332=TAS} adherens junction organization, cell junction assembly, cell-cell adhesion, cell-cell junction organization, homophilic cell adhesion integral to membrane, plasma membrane calcium ion binding, molecular_function Human CDHR1 ENSEMBL UniProtKB {GO:0005886=GO_REF:0000002, GO:0042622=GO_REF:0000019, GO:0005887=GO_REF:0000019, GO:0005509=GO_REF:0000002, GO:0016021=GO_REF:0000038, GO:0045494=GO_REF:0000019, GO:0007156=GO_REF:0000002} Q96JP9 Cadherin-related family member 1 protein 20130413 {GO:0005886=IEA, GO:0042622=IEA, GO:0005887=IEA, GO:0005509=IEA, GO:0016021=IEA, GO:0045494=IEA, GO:0007156=IEA} homophilic cell adhesion, photoreceptor cell maintenance integral to membrane, integral to plasma membrane, photoreceptor outer segment membrane, plasma membrane calcium ion binding Human Ensembl:ENSMUSP00000022337 CDHR2 UniProtKB UniProtKB {GO:0005515=PMID:12117771, GO:0030308=PMID:12117771, GO:0016324=GO_REF:0000039, GO:0030054=GO_REF:0000039, GO:0005509=GO_REF:0000002, GO:0016021=PMID:12117771, GO:0007155=PMID:12117771, GO:0007156=GO_REF:0000002} Q9BYE9 Cadherin-related family member 2 protein 20050302 {GO:0005515=IPI, GO:0030308=IDA, GO:0016324=IEA, GO:0030054=IEA, GO:0005509=IEA, GO:0016021=IDA, GO:0007155=IDA, GO:0007156=IEA} cell adhesion, homophilic cell adhesion, negative regulation of cell growth apical plasma membrane, cell junction, integral to membrane calcium ion binding, protein binding Human CDIPT Reactome UniProtKB {GO:0030145=GO_REF:0000019, GO:0005886=GO_REF:0000039, GO:0006661=Reactome:REACT_121000, GO:0043178=GO_REF:0000019, GO:0046341=GO_REF:0000019, GO:0044281=Reactome:REACT_111217, GO:0008654=GO_REF:0000002, GO:0019992=GO_REF:0000019, GO:0016780=GO_REF:0000002, GO:0016020=GO_REF:0000002, GO:0000139=GO_REF:0000039, GO:0005789=Reactome:REACT_121059, GO:0030246=GO_REF:0000019, GO:0016021=GO_REF:0000037, GO:0006644=Reactome:REACT_120870, GO:0016740=GO_REF:0000038, GO:0046474=Reactome:REACT_121401, GO:0003881=Reactome:REACT_121059} O14735 CDP-diacylglycerol--inositol 3-phosphatidyltransferase protein 20111102 {GO:0030145=IEA, GO:0005886=IEA, GO:0006661=TAS, GO:0043178=IEA, GO:0046341=IEA, GO:0044281=TAS, GO:0008654=IEA, GO:0019992=IEA, GO:0016780=IEA, GO:0016020=IEA, GO:0000139=IEA, GO:0005789=TAS, GO:0030246=IEA, GO:0016021=IEA, GO:0006644=TAS, GO:0016740=IEA, GO:0046474=TAS, GO:0003881=TAS} CDP-diacylglycerol metabolic process, glycerophospholipid biosynthetic process, phosphatidylinositol biosynthetic process, phospholipid biosynthetic process, phospholipid metabolic process, small molecule metabolic process Golgi membrane, endoplasmic reticulum membrane, integral to membrane, membrane, plasma membrane CDP-diacylglycerol-inositol 3-phosphatidyltransferase activity, alcohol binding, carbohydrate binding, diacylglycerol binding, manganese ion binding, phosphotransferase activity, for other substituted phosphate groups, transferase activity Human CDK1 BHF-UCL UniProtKB {GO:0007077=Reactome:REACT_160255, GO:0060045=GO_REF:0000019, GO:0005515=PMID:21041660, GO:0000236=Reactome:REACT_682, GO:0014070=GO_REF:0000019, GO:0033160=GO_REF:0000019, GO:0070301=GO_REF:0000019, GO:0030261=GO_REF:0000019, GO:0034501=PMID:18195732, GO:0014075=GO_REF:0000019, GO:0051403=Reactome:REACT_21308, GO:0048678=GO_REF:0000019, GO:0002756=Reactome:REACT_6809, GO:0007173=Reactome:REACT_9417, GO:0007411=Reactome:REACT_18266, GO:0000165=Reactome:REACT_634, GO:0002755=Reactome:REACT_27215, GO:0038124=Reactome:REACT_8006, GO:0038123=Reactome:REACT_8005, GO:0005815=GO_REF:0000039, GO:0034134=Reactome:REACT_7980, GO:0030332=GO_REF:0000019, GO:0007569=GO_REF:0000019, GO:0045740=GO_REF:0000019, GO:0009636=GO_REF:0000019, GO:0030496=PMID:11069302, GO:0002224=Reactome:REACT_9020, GO:0045931=GO_REF:0000019, GO:0035173=GO_REF:0000019, GO:0006281=PMID:21655336, GO:0008543=Reactome:REACT_9470, GO:0045087=Reactome:REACT_6802, GO:0055015=GO_REF:0000019, GO:0030544=GO_REF:0000019, GO:0000075=Reactome:REACT_1538, GO:0035666=Reactome:REACT_25281, GO:0034166=Reactome:REACT_9027, GO:0005654=Reactome:REACT_150132, GO:0000278=Reactome:REACT_152, GO:0046688=GO_REF:0000019, GO:0034162=Reactome:REACT_9047, GO:0046686=GO_REF:0000019, GO:0051301=GO_REF:0000037, GO:0004693=Reactome:REACT_1627, GO:0008286=Reactome:REACT_498, GO:0007095=GO_REF:0000019, GO:0034142=Reactome:REACT_6894, GO:0007264=Reactome:REACT_12077, GO:0007098=PMID:19364923, GO:0045471=GO_REF:0000019, GO:0031100=GO_REF:0000019, GO:0007265=Reactome:REACT_12033, GO:0005634=GO_REF:0000052, GO:0031145=Reactome:REACT_6850, GO:0005829=Reactome:REACT_160217, GO:0005739=PMID:19917720, GO:0000187=Reactome:REACT_1482, GO:0005737=GO_REF:0000052, GO:0000186=Reactome:REACT_12005, GO:0000082=Reactome:REACT_1783, GO:0000083=Reactome:REACT_683, GO:0000088=Reactome:REACT_765, GO:0000086=Reactome:REACT_2203, GO:0000087=Reactome:REACT_910, GO:0005876=PMID:11069302, GO:0034138=Reactome:REACT_6783, GO:0014823=GO_REF:0000019, GO:0048011=Reactome:REACT_11061, GO:0043066=PMID:11069302, GO:0042493=GO_REF:0000019, GO:0051437=Reactome:REACT_6904, GO:0006915=GO_REF:0000037, GO:0000226=PMID:21655336, GO:0005524=GO_REF:0000037, GO:0008353=PMID:12721286, GO:0051439=Reactome:REACT_6837, GO:0045995=PMID:21535261, GO:0006260=PMID:21655336, GO:0010628=GO_REF:0000019, GO:0014038=PMID:17200138, GO:0006461=GO_REF:0000019, GO:0004672=PMID:9001210, GO:0016477=PMID:17200138, GO:0004674=GO_REF:0000038, GO:0007344=PMID:21535261, GO:0034146=Reactome:REACT_9061} P06493 Cyclin-dependent kinase 1 protein 20110202 {GO:0007077=TAS, GO:0060045=IEA, GO:0005515=IPI, GO:0000236=TAS, GO:0014070=IEA, GO:0033160=IEA, GO:0070301=IEA, GO:0030261=IEA, GO:0034501=IDA, GO:0014075=IEA, GO:0051403=TAS, GO:0048678=IEA, GO:0002756=TAS, GO:0007173=TAS, GO:0007411=TAS, GO:0000165=TAS, GO:0002755=TAS, GO:0038124=TAS, GO:0038123=TAS, GO:0005815=IEA, GO:0034134=TAS, GO:0030332=IEA, GO:0007569=IEA, GO:0045740=IEA, GO:0009636=IEA, GO:0030496=IDA, GO:0002224=TAS, GO:0045931=IEA, GO:0035173=IEA, GO:0006281=TAS, GO:0008543=TAS, GO:0045087=TAS, GO:0055015=IEA, GO:0030544=IEA, GO:0000075=TAS, GO:0035666=TAS, GO:0034166=TAS, GO:0005654=TAS, GO:0000278=TAS, GO:0046688=IEA, GO:0034162=TAS, GO:0046686=IEA, GO:0051301=IEA, GO:0004693=TAS, GO:0008286=TAS, GO:0007095=IEA, GO:0034142=TAS, GO:0007264=TAS, GO:0007098=TAS, GO:0045471=IEA, GO:0031100=IEA, GO:0007265=TAS, GO:0005634=IDA, GO:0031145=TAS, GO:0005829=TAS, GO:0005739=TAS, GO:0000187=TAS, GO:0005737=IDA, GO:0000186=TAS, GO:0000082=TAS, GO:0000083=TAS, GO:0000088=TAS, GO:0000086=TAS, GO:0000087=TAS, GO:0005876=IDA, GO:0034138=TAS, GO:0014823=IEA, GO:0048011=TAS, GO:0043066=IDA, GO:0042493=IEA, GO:0051437=TAS, GO:0006915=IEA, GO:0000226=TAS, GO:0005524=IEA, GO:0008353=IDA, GO:0051439=TAS, GO:0045995=TAS, GO:0006260=TAS, GO:0010628=IEA, GO:0014038=TAS, GO:0006461=IEA, GO:0004672=NAS, GO:0016477=TAS, GO:0004674=IEA, GO:0007344=TAS, GO:0034146=TAS} DNA repair, DNA replication, G1/S transition of mitotic cell cycle, G2/M transition of mitotic cell cycle, M phase of mitotic cell cycle, MAPK cascade, MyD88-dependent toll-like receptor signaling pathway, MyD88-independent toll-like receptor signaling pathway, Ras protein signal transduction, TRIF-dependent toll-like receptor signaling pathway, activation of MAPK activity, activation of MAPKK activity, anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process, apoptotic process, axon guidance, cell aging, cell cycle checkpoint, cell division, cell migration, cellular response to hydrogen peroxide, centrosome cycle, chromosome condensation, epidermal growth factor receptor signaling pathway, fibroblast growth factor receptor signaling pathway, innate immune response, insulin receptor signaling pathway, microtubule cytoskeleton organization, mitotic G2 DNA damage checkpoint, mitotic cell cycle, mitotic nuclear envelope disassembly, mitotic prometaphase, mitotic prophase, negative regulation of apoptotic process, neurotrophin TRK receptor signaling pathway, organ regeneration, positive regulation of DNA replication, positive regulation of cardiac muscle cell proliferation, positive regulation of gene expression, positive regulation of mitotic cell cycle, positive regulation of protein import into nucleus, translocation, positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle, pronuclear fusion, protein complex assembly, protein localization to kinetochore, regulation of Schwann cell differentiation, regulation of embryonic development, regulation of transcription involved in G1/S phase of mitotic cell cycle, regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle, response to activity, response to amine stimulus, response to axon injury, response to cadmium ion, response to copper ion, response to drug, response to ethanol, response to organic cyclic compound, response to toxic substance, small GTPase mediated signal transduction, stress-activated MAPK cascade, toll-like receptor 10 signaling pathway, toll-like receptor 2 signaling pathway, toll-like receptor 3 signaling pathway, toll-like receptor 4 signaling pathway, toll-like receptor 5 signaling pathway, toll-like receptor 9 signaling pathway, toll-like receptor TLR1:TLR2 signaling pathway, toll-like receptor TLR6:TLR2 signaling pathway, toll-like receptor signaling pathway, ventricular cardiac muscle cell development cytoplasm, cytosol, microtubule organizing center, midbody, mitochondrion, nucleoplasm, nucleus, spindle microtubule ATP binding, Hsp70 protein binding, RNA polymerase II carboxy-terminal domain kinase activity, cyclin binding, cyclin-dependent protein serine/threonine kinase activity, histone kinase activity, protein binding, protein kinase activity, protein serine/threonine kinase activity Human UniProtKB:Q99741 CDK10 UniProtKB UniProtKB {GO:0005515=PMID:22939624, GO:0008285=PMID:8208557, GO:0016301=GO_REF:0000038, GO:0004674=GO_REF:0000002, GO:0007089=PMID:8208557, GO:0005524=GO_REF:0000037, GO:0004693=GO_REF:0000003} Q9UHL7 Cyclin-dependent kinase related protein protein 20130413 {GO:0005515=IPI, GO:0008285=TAS, GO:0016301=IEA, GO:0004674=IEA, GO:0007089=TAS, GO:0005524=IEA, GO:0004693=IEA} negative regulation of cell proliferation, traversing start control point of mitotic cell cycle ATP binding, cyclin-dependent protein serine/threonine kinase activity, kinase activity, protein binding, protein serine/threonine kinase activity Human UniProtKB-KW:KW-0418 CDK11A HPA UniProtKB {GO:0007067=PMID:1639388, GO:0006355=PMID:9750192, GO:0005737=GO_REF:0000052, GO:0004672=PMID:9750192, GO:0004674=PMID:12501247, GO:0006915=PMID:9750192, GO:0006468=PMID:12501247, GO:0005634=GO_REF:0000052, GO:0050684=PMID:12501247, GO:0001558=PMID:10882096, GO:0005524=PMID:12501247, GO:0004693=GO_REF:0000003} Q9UQ88 Cyclin-dependent kinase 11A protein 20101115 {GO:0007067=NAS, GO:0006355=NAS, GO:0005737=IDA, GO:0004672=NAS, GO:0004674=IDA, GO:0006915=NAS, GO:0006468=IDA, GO:0005634=IDA, GO:0050684=IDA, GO:0001558=IEP, GO:0005524=IDA, GO:0004693=IEA} apoptotic process, mitosis, protein phosphorylation, regulation of cell growth, regulation of mRNA processing, regulation of transcription, DNA-dependent cytoplasm, nucleus ATP binding, cyclin-dependent protein serine/threonine kinase activity, protein kinase activity, protein serine/threonine kinase activity Human CDK11B HPA UniProtKB {GO:0005515=PMID:12624090, GO:0006355=PMID:9750192, GO:0008283=PMID:8195233, GO:0006915=PMID:9750192, GO:0005634=GO_REF:0000052, GO:0050684=PMID:12501247, GO:0005524=PMID:12501247, GO:0001558=PMID:10882096, GO:0005737=GO_REF:0000052, GO:0007067=PMID:1639388, GO:0004672=PMID:8195233, GO:0004674=PMID:12501247, GO:0006468=PMID:12501247, GO:0004693=GO_REF:0000003} P21127 Cyclin-dependent kinase 11B protein 20101115 {GO:0005515=IPI, GO:0006355=NAS, GO:0008283=TAS, GO:0006915=NAS, GO:0005634=IDA, GO:0050684=IDA, GO:0005524=IDA, GO:0001558=IEP, GO:0005737=IDA, GO:0007067=NAS, GO:0004672=TAS, GO:0004674=IDA, GO:0006468=IDA, GO:0004693=IEA} apoptotic process, cell proliferation, mitosis, protein phosphorylation, regulation of cell growth, regulation of mRNA processing, regulation of transcription, DNA-dependent cytoplasm, nucleus ATP binding, cyclin-dependent protein serine/threonine kinase activity, protein binding, protein kinase activity, protein serine/threonine kinase activity Human CDK12 HPA UniProtKB {GO:0006397=GO_REF:0000037, GO:0070816=PMID:20952539, GO:0008380=GO_REF:0000024, GO:0005515=PMID:12841360, GO:0019908=GO_REF:0000024, GO:0030332=PMID:22012619, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0005524=GO_REF:0000037, GO:0008353=PMID:20952539, GO:0002944=PMID:22012619, GO:0046777=PMID:11683387, GO:0004672=PMID:11683387, GO:0016607=PMID:11683387, GO:0043405=PMID:19651820, GO:0004674=GO_REF:0000002, GO:0004693=GO_REF:0000003} Q9NYV4 Cyclin-dependent kinase 12 protein 20101115 {GO:0006397=IEA, GO:0070816=IMP, GO:0008380=ISS, GO:0005515=IPI, GO:0019908=ISS, GO:0030332=IPI, GO:0005730=IDA, GO:0005634=IDA, GO:0005524=IEA, GO:0008353=IMP, GO:0002944=IPI, GO:0046777=IDA, GO:0004672=IDA, GO:0016607=IDA, GO:0043405=IMP, GO:0004674=IEA, GO:0004693=IEA} RNA splicing, mRNA processing, phosphorylation of RNA polymerase II C-terminal domain, protein autophosphorylation, regulation of MAP kinase activity cyclin K-CDK12 complex, nuclear cyclin-dependent protein kinase holoenzyme complex, nuclear speck, nucleolus, nucleus ATP binding, RNA polymerase II carboxy-terminal domain kinase activity, cyclin binding, cyclin-dependent protein serine/threonine kinase activity, protein binding, protein kinase activity, protein serine/threonine kinase activity Human CDK13 PINC UniProtKB {GO:0070816=PMID:20952539, GO:0030097=PMID:1731328, GO:0005515=PMID:16721827, GO:0007088=PMID:1731328, GO:0008284=PMID:1731328, GO:0019908=GO_REF:0000024, GO:0030332=PMID:22012619, GO:0007275=PMID:1731328, GO:0005524=GO_REF:0000037, GO:0008353=PMID:20952539, GO:0002945=PMID:22012619, GO:0004672=PMID:1731328, GO:0016607=PMID:16721827, GO:0019048=GO_REF:0000037, GO:0000380=GO_REF:0000024, GO:0004693=GO_REF:0000003} Q14004 Cyclin-dependent kinase 13 protein 20030904 {GO:0070816=IDA, GO:0030097=IMP, GO:0005515=IPI, GO:0007088=TAS, GO:0008284=TAS, GO:0019908=ISS, GO:0030332=IPI, GO:0007275=TAS, GO:0005524=IEA, GO:0008353=IDA, GO:0002945=IPI, GO:0004672=TAS, GO:0016607=IDA, GO:0019048=IEA, GO:0000380=ISS, GO:0004693=IEA} alternative mRNA splicing, via spliceosome, hemopoiesis, multicellular organismal development, phosphorylation of RNA polymerase II C-terminal domain, positive regulation of cell proliferation, regulation of mitosis, virus-host interaction cyclin K-CDK13 complex, nuclear cyclin-dependent protein kinase holoenzyme complex, nuclear speck ATP binding, RNA polymerase II carboxy-terminal domain kinase activity, cyclin binding, cyclin-dependent protein serine/threonine kinase activity, protein binding, protein kinase activity Human CDK14 HPA UniProtKB {GO:0005515=PMID:22939624, GO:0005886=PMID:19524571, GO:0030332=PMID:20059949, GO:0005634=GO_REF:0000052, GO:0005524=GO_REF:0000037, GO:0060828=PMID:20059949, GO:0005829=GO_REF:0000019, GO:0005737=GO_REF:0000052, GO:0004672=GO_REF:0000019, GO:0004674=GO_REF:0000002, GO:0000086=PMID:20059949, GO:0000308=PMID:20059949, GO:0016055=GO_REF:0000037, GO:0051301=GO_REF:0000037, GO:0004693=PMID:20059949} O94921 Cyclin-dependent kinase 14 protein 20090616 {GO:0005515=IPI, GO:0005886=IDA, GO:0030332=IPI, GO:0005634=IDA, GO:0005524=IEA, GO:0060828=IDA, GO:0005829=IEA, GO:0005737=IDA, GO:0004672=IEA, GO:0004674=IEA, GO:0000086=IDA, GO:0000308=IDA, GO:0016055=IEA, GO:0051301=IEA, GO:0004693=IMP} G2/M transition of mitotic cell cycle, Wnt receptor signaling pathway, cell division, regulation of canonical Wnt receptor signaling pathway cytoplasm, cytoplasmic cyclin-dependent protein kinase holoenzyme complex, cytosol, nucleus, plasma membrane ATP binding, cyclin binding, cyclin-dependent protein serine/threonine kinase activity, protein binding, protein kinase activity, protein serine/threonine kinase activity Human CDK15 IntAct UniProtKB {GO:0005515=PMID:22939624, GO:0004674=GO_REF:0000002, GO:0005524=GO_REF:0000037, GO:0046872=GO_REF:0000037, GO:0004693=GO_REF:0000003} Q96Q40 Cyclin-dependent kinase 15 protein 20130415 {GO:0005515=IPI, GO:0004674=IEA, GO:0005524=IEA, GO:0046872=IEA, GO:0004693=IEA} ATP binding, cyclin-dependent protein serine/threonine kinase activity, metal ion binding, protein binding, protein serine/threonine kinase activity Human UniProtKB:P08238 CDK16 IntAct UniProtKB {GO:0005515=PMID:16091426, GO:0030133=GO_REF:0000039, GO:0043005=GO_REF:0000039, GO:0030054=GO_REF:0000037, GO:0007283=GO_REF:0000024, GO:0006887=GO_REF:0000024, GO:0005524=GO_REF:0000037, GO:0031175=GO_REF:0000024, GO:0031234=PMID:22184064, GO:0008021=GO_REF:0000024, GO:0005737=PMID:22798068, GO:0004674=PMID:22184064, GO:0006468=PMID:1437147, GO:0030252=GO_REF:0000024, GO:0061178=PMID:22798068, GO:0016772=GO_REF:0000002, GO:0004693=GO_REF:0000003} Q00536 Cyclin-dependent kinase 16 protein 20130415 {GO:0005515=IPI, GO:0030133=IEA, GO:0043005=IEA, GO:0030054=IEA, GO:0007283=ISS, GO:0006887=ISS, GO:0005524=IEA, GO:0031175=ISS, GO:0031234=IDA, GO:0008021=ISS, GO:0005737=IDA, GO:0004674=IDA, GO:0006468=TAS, GO:0030252=ISS, GO:0061178=IMP, GO:0016772=IEA, GO:0004693=IEA} exocytosis, growth hormone secretion, neuron projection development, protein phosphorylation, regulation of insulin secretion involved in cellular response to glucose stimulus, spermatogenesis cell junction, cytoplasm, extrinsic to internal side of plasma membrane, neuron projection, synaptic vesicle, transport vesicle ATP binding, cyclin-dependent protein serine/threonine kinase activity, protein binding, protein serine/threonine kinase activity, transferase activity, transferring phosphorus-containing groups Human UniProtKB:Q15436 CDK17 PINC UniProtKB {GO:0004672=PMID:1639063, GO:0004674=GO_REF:0000002, GO:0006468=PMID:1639063, GO:0005524=GO_REF:0000037, GO:0004693=GO_REF:0000003} Q00537 Cyclin-dependent kinase 17 protein 20030904 {GO:0004672=TAS, GO:0004674=IEA, GO:0006468=TAS, GO:0005524=IEA, GO:0004693=IEA} protein phosphorylation ATP binding, cyclin-dependent protein serine/threonine kinase activity, protein kinase activity, protein serine/threonine kinase activity Human CDK18 UniProtKB UniProtKB {GO:0007165=GO_REF:0000029, GO:0004672=GO_REF:0000002, GO:0004674=GO_REF:0000029, GO:0006468=GO_REF:0000029, GO:0005575=GO_REF:0000015, GO:0004871=GO_REF:0000029, GO:0005524=GO_REF:0000029, GO:0004693=GO_REF:0000003} Q07002 Cyclin-dependent kinase 18 protein 20061026 {GO:0007165=NAS, GO:0004672=IEA, GO:0004674=NAS, GO:0006468=NAS, GO:0005575=ND, GO:0004871=NAS, GO:0005524=NAS, GO:0004693=IEA} protein phosphorylation, signal transduction cellular_component ATP binding, cyclin-dependent protein serine/threonine kinase activity, protein kinase activity, protein serine/threonine kinase activity, signal transducer activity Human CDK19 UniProtKB UniProtKB {GO:0004672=GO_REF:0000002, GO:0004674=GO_REF:0000002, GO:0005524=GO_REF:0000037, GO:0004693=GO_REF:0000003, GO:0051301=GO_REF:0000038} Q9BWU1 Cyclin-dependent kinase 19 protein 20130413 {GO:0004672=IEA, GO:0004674=IEA, GO:0005524=IEA, GO:0004693=IEA, GO:0051301=IEA} cell division ATP binding, cyclin-dependent protein serine/threonine kinase activity, protein kinase activity, protein serine/threonine kinase activity Human EC:2.7.11.22 CDK2 GOC UniProtKB {GO:0005515=PMID:23455922, GO:0032298=GO_REF:0000019, GO:0000793=GO_REF:0000019, GO:0008284=PMID:10767298, GO:0015030=PMID:10995387, GO:0071732=PMID:20079829, GO:0007265=PMID:9054499, GO:0005634=PMID:10767298, GO:0031145=Reactome:REACT_6828, GO:0046872=GO_REF:0000037, GO:0005829=Reactome:REACT_9065, GO:0000084=Reactome:REACT_899, GO:0000085=Reactome:REACT_1915, GO:0000082=Reactome:REACT_1783, GO:0005737=PMID:10767298, GO:0000086=PMID:1653904, GO:0006813=GO_REF:0000019, GO:0006977=Reactome:REACT_1625, GO:0005667=GO_REF:0000019, GO:0000806=GO_REF:0000019, GO:0005813=PMID:19238148, GO:0000781=GO_REF:0000019, GO:0030332=PMID:1653904, GO:0000805=GO_REF:0000019, GO:0016572=PMID:8692841, GO:0005524=GO_REF:0000037, GO:0051439=Reactome:REACT_6837, GO:0006260=Reactome:REACT_6769, GO:0051298=PMID:19238148, GO:0007067=GO_REF:0000037, GO:0035173=PMID:8692841, GO:0006281=GO_REF:0000037, GO:0007126=PMID:19238148, GO:0060968=PMID:20935635, GO:0007596=Reactome:REACT_604, GO:0004674=GO_REF:0000002, GO:0000307=PMID:8692841, GO:0000075=Reactome:REACT_1538, GO:0005654=Reactome:REACT_111202, GO:0031571=PMID:21319273, GO:0000278=Reactome:REACT_152, GO:0045893=GO_REF:0000019, GO:0005768=PMID:21262353, GO:0004693=Reactome:REACT_9023, GO:0051301=GO_REF:0000037} P24941 Cyclin-dependent kinase 2 protein 20130413 {GO:0005515=IPI, GO:0032298=IEA, GO:0000793=IEA, GO:0008284=IDA, GO:0015030=IDA, GO:0071732=TAS, GO:0007265=IEP, GO:0005634=IDA, GO:0031145=TAS, GO:0046872=IEA, GO:0005829=TAS, GO:0000084=TAS, GO:0000085=TAS, GO:0000082=TAS, GO:0005737=IDA, GO:0000086=NAS, GO:0006813=IEA, GO:0006977=TAS, GO:0005667=IEA, GO:0000806=IEA, GO:0005813=TAS, GO:0000781=IEA, GO:0030332=IDA, GO:0000805=IEA, GO:0016572=IDA, GO:0005524=IEA, GO:0051439=TAS, GO:0006260=TAS, GO:0051298=TAS, GO:0007067=IEA, GO:0035173=IDA, GO:0006281=IEA, GO:0007126=TAS, GO:0060968=IDA, GO:0007596=TAS, GO:0004674=IEA, GO:0000307=IDA, GO:0000075=TAS, GO:0005654=TAS, GO:0031571=TAS, GO:0000278=TAS, GO:0045893=IEA, GO:0005768=IDA, GO:0004693=TAS, GO:0051301=IEA} DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest, DNA repair, DNA replication, G1/S transition of mitotic cell cycle, G2 phase of mitotic cell cycle, G2/M transition of mitotic cell cycle, Ras protein signal transduction, S phase of mitotic cell cycle, anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process, blood coagulation, cell cycle checkpoint, cell division, cellular response to nitric oxide, centrosome duplication, histone phosphorylation, meiosis, mitosis, mitotic G1 DNA damage checkpoint, mitotic cell cycle, positive regulation of DNA-dependent DNA replication initiation, positive regulation of cell proliferation, positive regulation of transcription, DNA-dependent, potassium ion transport, regulation of gene silencing, regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle Cajal body, X chromosome, Y chromosome, centrosome, chromosome, telomeric region, condensed chromosome, cyclin-dependent protein kinase holoenzyme complex, cytoplasm, cytosol, endosome, nucleoplasm, nucleus, transcription factor complex ATP binding, cyclin binding, cyclin-dependent protein serine/threonine kinase activity, histone kinase activity, metal ion binding, protein binding, protein serine/threonine kinase activity Human CDK20 UniProtKB UniProtKB {GO:0005515=PMID:21986944, GO:0005929=GO_REF:0000039, GO:0005737=GO_REF:0000039, GO:0005634=GO_REF:0000039, GO:0007275=GO_REF:0000037, GO:0005524=GO_REF:0000037, GO:0004693=GO_REF:0000003, GO:0051301=GO_REF:0000037} Q8IZL9 Cyclin-dependent kinase 20 protein 20120708 {GO:0005515=IPI, GO:0005929=IEA, GO:0005737=IEA, GO:0005634=IEA, GO:0007275=IEA, GO:0005524=IEA, GO:0004693=IEA, GO:0051301=IEA} cell division, multicellular organismal development cilium, cytoplasm, nucleus ATP binding, cyclin-dependent protein serine/threonine kinase activity, protein binding Human UniProtKB:P20794 CDK2AP1 PINC UniProtKB {GO:0000084=PMID:9506968, GO:0006261=PMID:9506968, GO:0005737=PMID:9506968, GO:0006468=PMID:9506968, GO:0005634=PMID:9506968, GO:0003677=PMID:9506968} O14519 Cyclin-dependent kinase 2-associated protein 1 protein 20030904 {GO:0000084=TAS, GO:0006261=TAS, GO:0005737=TAS, GO:0006468=TAS, GO:0005634=TAS, GO:0003677=TAS} DNA-dependent DNA replication, S phase of mitotic cell cycle, protein phosphorylation cytoplasm, nucleus DNA binding Human CDK2AP2 null null {} null null null null {} null null null CDK3 UniProtKB UniProtKB {GO:0000082=PMID:8846921, GO:0007067=GO_REF:0000037, GO:0008283=PMID:18794154, GO:0004674=GO_REF:0000038, GO:0005524=GO_REF:0000037, GO:0045023=PMID:15084261, GO:0004693=GO_REF:0000003, GO:0051301=GO_REF:0000037} Q00526 Cyclin-dependent kinase 3 protein 20110912 {GO:0000082=TAS, GO:0007067=IEA, GO:0008283=TAS, GO:0004674=IEA, GO:0005524=IEA, GO:0045023=TAS, GO:0004693=IEA, GO:0051301=IEA} G0 to G1 transition, G1/S transition of mitotic cell cycle, cell division, cell proliferation, mitosis ATP binding, cyclin-dependent protein serine/threonine kinase activity, protein serine/threonine kinase activity Human CDK4 UniProtKB UniProtKB {GO:0010468=PMID:17420273, GO:0005515=PMID:8741839, GO:0008284=PMID:7603984, GO:0048471=GO_REF:0000019, GO:0031100=GO_REF:0000019, GO:0005634=PMID:16109376, GO:0048146=PMID:17420273, GO:0032403=GO_REF:0000019, GO:0005829=Reactome:REACT_7947, GO:0000084=Reactome:REACT_899, GO:0000082=PMID:7603984, GO:0051726=GO_REF:0000019, GO:0000080=Reactome:REACT_1590, GO:0000785=PMID:18827403, GO:0010288=GO_REF:0000019, GO:0005667=GO_REF:0000019, GO:0031965=PMID:18827403, GO:0043065=GO_REF:0000019, GO:0030332=GO_REF:0000019, GO:0042493=PMID:18291362, GO:0005730=PMID:18827403, GO:0009636=GO_REF:0000019, GO:0045727=GO_REF:0000019, GO:0033574=GO_REF:0000019, GO:0005524=GO_REF:0000038, GO:0007165=GO_REF:0000019, GO:0045793=GO_REF:0000019, GO:0004672=GO_REF:0000002, GO:0004674=GO_REF:0000038, GO:0000307=PMID:17420273, GO:0055093=GO_REF:0000019, GO:0007623=GO_REF:0000019, GO:0006468=PMID:8114739, GO:0005654=Reactome:REACT_111248, GO:0005923=GO_REF:0000019, GO:0000278=Reactome:REACT_152, GO:0004693=PMID:8114739, GO:0051301=GO_REF:0000037} Q96BE9 Cyclin-dependent kinase 4 protein 20130413 {GO:0010468=IMP, GO:0005515=IPI, GO:0008284=IMP, GO:0048471=IEA, GO:0031100=IEA, GO:0005634=IDA, GO:0048146=IMP, GO:0032403=IEA, GO:0005829=TAS, GO:0000084=TAS, GO:0000082=IMP, GO:0051726=IEA, GO:0000080=TAS, GO:0000785=IDA, GO:0010288=IEA, GO:0005667=IEA, GO:0031965=IDA, GO:0043065=IEA, GO:0030332=IEA, GO:0042493=IGI, GO:0005730=IDA, GO:0009636=IEA, GO:0045727=IEA, GO:0033574=IEA, GO:0005524=IEA, GO:0007165=IEA, GO:0045793=IEA, GO:0004672=IEA, GO:0004674=IEA, GO:0000307=IDA, GO:0055093=IEA, GO:0007623=IEA, GO:0006468=IDA, GO:0005654=TAS, GO:0005923=IEA, GO:0000278=TAS, GO:0004693=IDA, GO:0051301=IEA} G1 phase of mitotic cell cycle, G1/S transition of mitotic cell cycle, S phase of mitotic cell cycle, cell division, circadian rhythm, mitotic cell cycle, organ regeneration, positive regulation of apoptotic process, positive regulation of cell proliferation, positive regulation of cell size, positive regulation of fibroblast proliferation, positive regulation of translation, protein phosphorylation, regulation of cell cycle, regulation of gene expression, response to drug, response to hyperoxia, response to lead ion, response to testosterone stimulus, response to toxic substance, signal transduction chromatin, cyclin-dependent protein kinase holoenzyme complex, cytosol, nuclear membrane, nucleolus, nucleoplasm, nucleus, perinuclear region of cytoplasm, tight junction, transcription factor complex ATP binding, cyclin binding, cyclin-dependent protein serine/threonine kinase activity, protein binding, protein complex binding, protein kinase activity, protein serine/threonine kinase activity Human UniProtKB-KW:KW-0067 CDK5 IntAct UniProtKB {GO:0071156=PMID:21473899, GO:0005515=PMID:23455922, GO:0031594=GO_REF:0000024, GO:0030054=GO_REF:0000037, GO:0048709=PMID:18042622, GO:0021697=GO_REF:0000019, GO:0050321=GO_REF:0000024, GO:2000251=PMID:21473899, GO:0009790=GO_REF:0000024, GO:0051402=PMID:21473899, GO:0006886=GO_REF:0000019, GO:0031175=GO_REF:0000024, GO:0043525=GO_REF:0000024, GO:0046777=GO_REF:0000019, GO:0018105=PMID:21145489, GO:0007411=Reactome:REACT_18266, GO:0048167=GO_REF:0000024, GO:0016301=GO_REF:0000024, GO:0045211=GO_REF:0000037, GO:0018107=GO_REF:0000019, GO:0045860=GO_REF:0000019, GO:0043025=GO_REF:0000024, GO:0031397=GO_REF:0000019, GO:0061001=GO_REF:0000024, GO:0043125=GO_REF:0000024, GO:0030334=GO_REF:0000019, GO:0060079=GO_REF:0000019, GO:0014069=GO_REF:0000024, GO:0090314=GO_REF:0000019, GO:0048488=PMID:21473899, GO:0045786=GO_REF:0000019, GO:0016079=PMID:21473899, GO:0007416=PMID:21473899, GO:0030027=GO_REF:0000039, GO:0005176=GO_REF:0000024, GO:0016310=PMID:20357208, GO:0070509=GO_REF:0000019, GO:0008045=GO_REF:0000019, GO:0030549=GO_REF:0000024, GO:0046875=GO_REF:0000019, GO:0007519=GO_REF:0000019, GO:0008542=GO_REF:0000019, GO:0045892=PMID:20357208, GO:0004693=GO_REF:0000024, GO:0051301=GO_REF:0000037, GO:0030424=GO_REF:0000024, GO:0005886=GO_REF:0000039, GO:0008283=PMID:8090221, GO:0048148=GO_REF:0000019, GO:0007268=PMID:21473899, GO:0035418=GO_REF:0000019, GO:0048675=PMID:21473899, GO:0005634=GO_REF:0000024, GO:0030175=GO_REF:0000019, GO:0030425=GO_REF:0000024, GO:0005829=Reactome:REACT_19321, GO:0030426=GO_REF:0000024, GO:0032092=GO_REF:0000019, GO:0046826=GO_REF:0000019, GO:0002039=GO_REF:0000019, GO:0045055=GO_REF:0000019, GO:0005737=GO_REF:0000024, GO:0031914=GO_REF:0000019, GO:0033136=GO_REF:0000019, GO:0030182=PMID:21473899, GO:0001963=GO_REF:0000019, GO:0043204=GO_REF:0000039, GO:0021954=GO_REF:0000019, GO:0014044=GO_REF:0000019, GO:0035249=GO_REF:0000019, GO:0016533=GO_REF:0000019, GO:0042981=PMID:21473899, GO:0021819=GO_REF:0000019, GO:0005524=GO_REF:0000037, GO:0019233=GO_REF:0000019, GO:0006913=GO_REF:0000019, GO:0048813=GO_REF:0000019, GO:0021766=GO_REF:0000019, GO:0022038=GO_REF:0000019, GO:0004672=PMID:1639063, GO:0016020=GO_REF:0000024, GO:0007160=GO_REF:0000019, GO:0007596=Reactome:REACT_604, GO:0030866=GO_REF:0000019, GO:0045956=GO_REF:0000019, GO:0004674=Reactome:REACT_19285, GO:0032801=GO_REF:0000019, GO:0043113=GO_REF:0000019, GO:0001764=PMID:21473899} Q00535 Cyclin-dependent kinase 5 protein 20130415 {GO:0071156=TAS, GO:0005515=IPI, GO:0031594=ISS, GO:0030054=IEA, GO:0048709=IDA, GO:0021697=IEA, GO:0050321=ISS, GO:2000251=TAS, GO:0009790=ISS, GO:0051402=TAS, GO:0006886=IEA, GO:0031175=ISS, GO:0043525=ISS, GO:0046777=IEA, GO:0018105=IDA, GO:0007411=TAS, GO:0048167=ISS, GO:0016301=ISS, GO:0045211=IEA, GO:0018107=IEA, GO:0045860=IEA, GO:0043025=ISS, GO:0031397=IEA, GO:0061001=ISS, GO:0043125=ISS, GO:0030334=IEA, GO:0060079=IEA, GO:0014069=ISS, GO:0090314=IEA, GO:0048488=TAS, GO:0045786=IEA, GO:0016079=TAS, GO:0007416=TAS, GO:0030027=IEA, GO:0005176=ISS, GO:0016310=IDA, GO:0070509=IEA, GO:0008045=IEA, GO:0030549=ISS, GO:0046875=IEA, GO:0007519=IEA, GO:0008542=IEA, GO:0045892=IMP, GO:0004693=ISS, GO:0051301=IEA, GO:0030424=ISS, GO:0005886=IEA, GO:0008283=TAS, GO:0048148=IEA, GO:0007268=TAS, GO:0035418=IEA, GO:0048675=TAS, GO:0005634=ISS, GO:0030175=IEA, GO:0030425=ISS, GO:0005829=TAS, GO:0030426=ISS, GO:0032092=IEA, GO:0046826=IEA, GO:0002039=IEA, GO:0045055=IEA, GO:0005737=ISS, GO:0031914=IEA, GO:0033136=IEA, GO:0030182=TAS, GO:0001963=IEA, GO:0043204=IEA, GO:0021954=IEA, GO:0014044=IEA, GO:0035249=IEA, GO:0016533=IEA, GO:0042981=TAS, GO:0021819=IEA, GO:0005524=IEA, GO:0019233=IEA, GO:0006913=IEA, GO:0048813=IEA, GO:0021766=IEA, GO:0022038=IEA, GO:0004672=TAS, GO:0016020=ISS, GO:0007160=IEA, GO:0007596=TAS, GO:0030866=IEA, GO:0045956=IEA, GO:0004674=TAS, GO:0032801=IEA, GO:0043113=IEA, GO:0001764=TAS} Schwann cell development, axon extension, axon guidance, behavioral response to cocaine, blood coagulation, calcium ion import, cell division, cell proliferation, cell-matrix adhesion, central nervous system neuron development, cerebellar cortex formation, corpus callosum development, cortical actin cytoskeleton organization, dendrite morphogenesis, embryo development, hippocampus development, intracellular protein transport, layer formation in cerebral cortex, motor neuron axon guidance, negative regulation of cell cycle, negative regulation of protein export from nucleus, negative regulation of protein ubiquitination, negative regulation of synaptic plasticity, negative regulation of transcription, DNA-dependent, neuron apoptotic process, neuron differentiation, neuron migration, neuron projection development, nucleocytoplasmic transport, oligodendrocyte differentiation, peptidyl-serine phosphorylation, peptidyl-threonine phosphorylation, phosphorylation, positive regulation of actin cytoskeleton reorganization, positive regulation of calcium ion-dependent exocytosis, positive regulation of neuron apoptotic process, positive regulation of protein binding, positive regulation of protein kinase activity, positive regulation of protein targeting to membrane, protein autophosphorylation, protein localization to synapse, receptor catabolic process, receptor clustering, regulated secretory pathway, regulation of apoptotic process, regulation of cell cycle arrest, regulation of cell migration, regulation of dendritic spine morphogenesis, regulation of excitatory postsynaptic membrane potential, regulation of synaptic plasticity, sensory perception of pain, serine phosphorylation of STAT3 protein, skeletal muscle tissue development, synapse assembly, synaptic transmission, synaptic transmission, dopaminergic, synaptic transmission, glutamatergic, synaptic vesicle endocytosis, synaptic vesicle exocytosis, visual learning axon, cell junction, cyclin-dependent protein kinase 5 holoenzyme complex, cytoplasm, cytosol, dendrite, filopodium, growth cone, lamellipodium, membrane, neuromuscular junction, neuronal cell body, nucleus, perikaryon, plasma membrane, postsynaptic density, postsynaptic membrane ATP binding, ErbB-2 class receptor binding, ErbB-3 class receptor binding, acetylcholine receptor activator activity, cyclin-dependent protein serine/threonine kinase activity, ephrin receptor binding, kinase activity, p53 binding, protein binding, protein kinase activity, protein serine/threonine kinase activity, tau-protein kinase activity Human UniProtKB:P46527 CDK5R1 IntAct UniProtKB {GO:0005515=PMID:15689152, GO:0031594=GO_REF:0000024, GO:0009790=GO_REF:0000024, GO:0031175=GO_REF:0000024, GO:0043525=GO_REF:0000024, GO:0007413=GO_REF:0000024, GO:0018105=PMID:12832520, GO:0016301=GO_REF:0000024, GO:0007411=Reactome:REACT_18266, GO:0021722=GO_REF:0000019, GO:0032956=GO_REF:0000019, GO:0018107=PMID:12832520, GO:0043025=GO_REF:0000024, GO:0061001=GO_REF:0000024, GO:0045296=GO_REF:0000024, GO:0019901=PMID:12832520, GO:0005509=GO_REF:0000024, GO:0090314=GO_REF:0000019, GO:0014069=GO_REF:0000024, GO:0021549=GO_REF:0000019, GO:0007213=GO_REF:0000024, GO:0070507=GO_REF:0000019, GO:0035235=GO_REF:0000024, GO:0046875=GO_REF:0000019, GO:0007420=PMID:10915792, GO:0043539=PMID:12832520, GO:0045892=PMID:20357208, GO:0004693=GO_REF:0000019, GO:0030424=GO_REF:0000024, GO:0048471=PMID:12832520, GO:0005886=GO_REF:0000039, GO:0008283=PMID:8090221, GO:0005634=GO_REF:0000024, GO:0000079=PMID:7592934, GO:0030425=GO_REF:0000024, GO:0005829=Reactome:REACT_19321, GO:0030426=GO_REF:0000024, GO:0005737=GO_REF:0000024, GO:0043197=GO_REF:0000024, GO:0033136=GO_REF:0000019, GO:0043292=GO_REF:0000024, GO:0030182=GO_REF:0000024, GO:0007158=GO_REF:0000024, GO:0048013=GO_REF:0000024, GO:0016534=GO_REF:0000019, GO:0016533=GO_REF:0000002, GO:0021819=GO_REF:0000019, GO:0021766=GO_REF:0000019, GO:0004672=PMID:7592934, GO:0016020=GO_REF:0000024, GO:0045664=PMID:10721722, GO:0001764=GO_REF:0000024} Q15078 Cyclin-dependent kinase 5 activator 1 protein 20130415 {GO:0005515=IPI, GO:0031594=ISS, GO:0009790=ISS, GO:0031175=ISS, GO:0043525=ISS, GO:0007413=ISS, GO:0018105=IDA, GO:0016301=ISS, GO:0007411=TAS, GO:0021722=IEA, GO:0032956=IEA, GO:0018107=IDA, GO:0043025=ISS, GO:0061001=ISS, GO:0045296=ISS, GO:0019901=IPI, GO:0005509=ISS, GO:0090314=IEA, GO:0014069=ISS, GO:0021549=IEA, GO:0007213=ISS, GO:0070507=IEA, GO:0035235=ISS, GO:0046875=IEA, GO:0007420=NAS, GO:0043539=IDA, GO:0045892=IMP, GO:0004693=IEA, GO:0030424=ISS, GO:0048471=IDA, GO:0005886=IEA, GO:0008283=TAS, GO:0005634=ISS, GO:0000079=TAS, GO:0030425=ISS, GO:0005829=TAS, GO:0030426=ISS, GO:0005737=ISS, GO:0043197=ISS, GO:0033136=IEA, GO:0043292=ISS, GO:0030182=ISS, GO:0007158=ISS, GO:0048013=ISS, GO:0016534=IEA, GO:0016533=IEA, GO:0021819=IEA, GO:0021766=IEA, GO:0004672=TAS, GO:0016020=ISS, GO:0045664=NAS, GO:0001764=ISS} G-protein coupled acetylcholine receptor signaling pathway, axon guidance, axonal fasciculation, brain development, cell proliferation, cerebellum development, embryo development, ephrin receptor signaling pathway, hippocampus development, ionotropic glutamate receptor signaling pathway, layer formation in cerebral cortex, negative regulation of transcription, DNA-dependent, neuron cell-cell adhesion, neuron differentiation, neuron migration, neuron projection development, peptidyl-serine phosphorylation, peptidyl-threonine phosphorylation, positive regulation of neuron apoptotic process, positive regulation of protein targeting to membrane, regulation of actin cytoskeleton organization, regulation of cyclin-dependent protein serine/threonine kinase activity, regulation of dendritic spine morphogenesis, regulation of microtubule cytoskeleton organization, regulation of neuron differentiation, serine phosphorylation of STAT3 protein, superior olivary nucleus maturation axon, contractile fiber, cyclin-dependent protein kinase 5 holoenzyme complex, cytoplasm, cytosol, dendrite, dendritic spine, growth cone, membrane, neuromuscular junction, neuronal cell body, nucleus, perinuclear region of cytoplasm, plasma membrane, postsynaptic density cadherin binding, calcium ion binding, cyclin-dependent protein kinase 5 activator activity, cyclin-dependent protein serine/threonine kinase activity, ephrin receptor binding, kinase activity, protein binding, protein kinase activity, protein kinase binding, protein serine/threonine kinase activator activity Human UniProtKB:Q00535 CDK5R2 PINC UniProtKB {GO:0021766=GO_REF:0000019, GO:0005737=GO_REF:0000019, GO:0005886=GO_REF:0000039, GO:0045956=GO_REF:0000019, GO:0021722=GO_REF:0000019, GO:0016534=GO_REF:0000019, GO:0016533=GO_REF:0000002, GO:0021549=GO_REF:0000019, GO:0000079=PMID:7592934, GO:0021819=GO_REF:0000019, GO:0001764=GO_REF:0000019, GO:0008289=GO_REF:0000037} Q13319 Cyclin-dependent kinase 5 activator 2 protein 20030904 {GO:0021766=IEA, GO:0005737=IEA, GO:0005886=IEA, GO:0045956=IEA, GO:0021722=IEA, GO:0016534=IEA, GO:0016533=IEA, GO:0021549=IEA, GO:0000079=TAS, GO:0021819=IEA, GO:0001764=IEA, GO:0008289=IEA} cerebellum development, hippocampus development, layer formation in cerebral cortex, neuron migration, positive regulation of calcium ion-dependent exocytosis, regulation of cyclin-dependent protein serine/threonine kinase activity, superior olivary nucleus maturation cyclin-dependent protein kinase 5 holoenzyme complex, cytoplasm, plasma membrane cyclin-dependent protein kinase 5 activator activity, lipid binding Human CDK5RAP1 UniProtKB UniProtKB {GO:0051539=GO_REF:0000037, GO:0019901=PMID:10721722, GO:0045736=PMID:11882646, GO:0005575=GO_REF:0000015, GO:0003824=GO_REF:0000002, GO:0032403=GO_REF:0000019, GO:0006400=GO_REF:0000002, GO:0046872=GO_REF:0000037, GO:0005737=GO_REF:0000002, GO:0007420=PMID:10915792, GO:0045664=PMID:10721722, GO:0009451=GO_REF:0000002, GO:0016740=GO_REF:0000002} Q96SZ6 CDK5 regulatory subunit-associated protein 1 protein 20061026 {GO:0051539=IEA, GO:0019901=NAS, GO:0045736=IDA, GO:0005575=ND, GO:0003824=IEA, GO:0032403=IEA, GO:0006400=IEA, GO:0046872=IEA, GO:0005737=IEA, GO:0007420=NAS, GO:0045664=NAS, GO:0009451=IEA, GO:0016740=IEA} RNA modification, brain development, negative regulation of cyclin-dependent protein serine/threonine kinase activity, regulation of neuron differentiation, tRNA modification cellular_component, cytoplasm 4 iron, 4 sulfur cluster binding, catalytic activity, metal ion binding, protein complex binding, protein kinase binding, transferase activity Human CDK5RAP2 HPA UniProtKB {GO:0008017=PMID:14654843, GO:0005515=PMID:19282672, GO:0005516=PMID:20466722, GO:0048471=PMID:17959831, GO:0030054=GO_REF:0000052, GO:0044212=PMID:19282672, GO:0001578=PMID:19553473, GO:0000132=GO_REF:0000024, GO:0032403=GO_REF:0000019, GO:0005829=Reactome:REACT_15470, GO:0005737=PMID:19282672, GO:0007059=PMID:19282672, GO:0015631=PMID:17959831, GO:0000086=Reactome:REACT_2203, GO:0005856=PMID:10721722, GO:0000242=PMID:17959831, GO:0022008=GO_REF:0000024, GO:0090231=PMID:19282672, GO:0005813=GO_REF:0000052, GO:0005794=PMID:20466722, GO:0019901=PMID:10721722, GO:0005874=PMID:19553473, GO:0000226=PMID:17959831, GO:0046600=GO_REF:0000024, GO:0051297=PMID:18042621, GO:0000922=PMID:19282672, GO:0045665=GO_REF:0000019, GO:0007420=GO_REF:0000024, GO:0045664=PMID:10721722, GO:0000278=Reactome:REACT_152, GO:0045893=PMID:19282672} Q96SN8 CDK5 regulatory subunit-associated protein 2 protein 20111111 {GO:0008017=IDA, GO:0005515=IPI, GO:0005516=IPI, GO:0048471=IDA, GO:0030054=IDA, GO:0044212=IDA, GO:0001578=IDA, GO:0000132=ISS, GO:0032403=IEA, GO:0005829=TAS, GO:0005737=IDA, GO:0007059=IMP, GO:0015631=IPI, GO:0000086=TAS, GO:0005856=NAS, GO:0000242=IDA, GO:0022008=ISS, GO:0090231=IDA, GO:0005813=IDA, GO:0005794=IDA, GO:0019901=IPI, GO:0005874=IDA, GO:0000226=IDA, GO:0046600=ISS, GO:0051297=IMP, GO:0000922=IDA, GO:0045665=IEA, GO:0007420=ISS, GO:0045664=NAS, GO:0000278=TAS, GO:0045893=IDA} G2/M transition of mitotic cell cycle, brain development, centrosome organization, chromosome segregation, establishment of mitotic spindle orientation, microtubule bundle formation, microtubule cytoskeleton organization, mitotic cell cycle, negative regulation of centriole replication, negative regulation of neuron differentiation, neurogenesis, positive regulation of transcription, DNA-dependent, regulation of neuron differentiation, regulation of spindle checkpoint Golgi apparatus, cell junction, centrosome, cytoplasm, cytoskeleton, cytosol, microtubule, pericentriolar material, perinuclear region of cytoplasm, spindle pole calmodulin binding, microtubule binding, protein binding, protein complex binding, protein kinase binding, transcription regulatory region DNA binding, tubulin binding Human CDK5RAP3 IntAct UniProtKB {GO:0005515=PMID:17785205, GO:0019901=PMID:10721722, GO:0007420=PMID:10915792, GO:0045944=GO_REF:0000019, GO:0045664=PMID:10721722, GO:0000079=GO_REF:0000024, GO:0005575=GO_REF:0000015} Q96JB5 CDK5 regulatory subunit-associated protein 3 protein 20130415 {GO:0005515=IPI, GO:0019901=NAS, GO:0007420=NAS, GO:0045944=IEA, GO:0045664=NAS, GO:0000079=ISS, GO:0005575=ND} brain development, positive regulation of transcription from RNA polymerase II promoter, regulation of cyclin-dependent protein serine/threonine kinase activity, regulation of neuron differentiation cellular_component protein binding, protein kinase binding Human UniProtKB:Q04206 CDK6 BHF-UCL UniProtKB {GO:0005515=PMID:8001816, GO:0010468=PMID:15254224, GO:0008285=PMID:16294322, GO:0050680=PMID:14985467, GO:0048699=PMID:21319271, GO:2000145=PMID:16767702, GO:0005634=PMID:14985467, GO:0048146=PMID:17420273, GO:0005829=Reactome:REACT_7947, GO:0005737=PMID:14985467, GO:0000082=PMID:16294322, GO:0007219=GO_REF:0000019, GO:0002244=GO_REF:0000019, GO:0045638=PMID:17431401, GO:0043697=PMID:12861051, GO:0007050=PMID:16294322, GO:0000080=PMID:8114739, GO:2000773=PMID:17420273, GO:0021542=PMID:21319271, GO:0033077=GO_REF:0000019, GO:0030332=PMID:8114739, GO:0003323=PMID:20668294, GO:0009615=PMID:16548883, GO:0045786=PMID:14985467, GO:0060218=GO_REF:0000019, GO:0001726=PMID:10205165, GO:0005524=PMID:9751050, GO:0042063=PMID:12861051, GO:0010628=GO_REF:0000019, GO:0045668=PMID:15254224, GO:0021670=PMID:21319271, GO:0014002=PMID:16767702, GO:0000307=PMID:17420273, GO:0045646=PMID:12833137, GO:0006468=PMID:8114739, GO:0045596=PMID:16294322, GO:0000278=Reactome:REACT_152, GO:0001954=PMID:10205165, GO:0051301=GO_REF:0000037, GO:0004693=PMID:8114739} Q00534 Cyclin-dependent kinase 6 protein 20071120 {GO:0005515=IPI, GO:0010468=IDA, GO:0008285=TAS, GO:0050680=IMP, GO:0048699=ISS, GO:2000145=ISS, GO:0005634=IDA, GO:0048146=IMP, GO:0005829=TAS, GO:0005737=IDA, GO:0000082=TAS, GO:0007219=IEA, GO:0002244=IEA, GO:0045638=IDA, GO:0043697=IMP, GO:0007050=TAS, GO:0000080=IEP, GO:2000773=IDA, GO:0021542=ISS, GO:0033077=IEA, GO:0030332=IPI, GO:0003323=IDA, GO:0009615=IEP, GO:0045786=IDA, GO:0060218=IEA, GO:0001726=IDA, GO:0005524=IDA, GO:0042063=IMP, GO:0010628=IEA, GO:0045668=IDA, GO:0021670=ISS, GO:0014002=ISS, GO:0000307=IDA, GO:0045646=IMP, GO:0006468=IDA, GO:0045596=TAS, GO:0000278=TAS, GO:0001954=IDA, GO:0051301=IEA, GO:0004693=IDA} G1 phase of mitotic cell cycle, G1/S transition of mitotic cell cycle, Notch signaling pathway, T cell differentiation in thymus, astrocyte development, cell cycle arrest, cell dedifferentiation, cell division, dentate gyrus development, generation of neurons, gliogenesis, hematopoietic progenitor cell differentiation, hematopoietic stem cell differentiation, lateral ventricle development, mitotic cell cycle, negative regulation of cell cycle, negative regulation of cell differentiation, negative regulation of cell proliferation, negative regulation of cellular senescence, negative regulation of epithelial cell proliferation, negative regulation of myeloid cell differentiation, negative regulation of osteoblast differentiation, positive regulation of cell-matrix adhesion, positive regulation of fibroblast proliferation, positive regulation of gene expression, protein phosphorylation, regulation of cell motility, regulation of erythrocyte differentiation, regulation of gene expression, response to virus, type B pancreatic cell development cyclin-dependent protein kinase holoenzyme complex, cytoplasm, cytosol, nucleus, ruffle ATP binding, cyclin binding, cyclin-dependent protein serine/threonine kinase activity, protein binding Human UniProtKB:P42773 CDK7 HPA UniProtKB {GO:0022415=Reactome:REACT_6361, GO:0010467=Reactome:REACT_71, GO:0006368=Reactome:REACT_2089, GO:0048471=GO_REF:0000039, GO:0006367=Reactome:REACT_1851, GO:0006366=Reactome:REACT_1366, GO:0008283=PMID:7533895, GO:0006363=Reactome:REACT_1074, GO:0006362=Reactome:REACT_2204, GO:0006361=Reactome:REACT_1974, GO:0006360=Reactome:REACT_1309, GO:0005634=GO_REF:0000052, GO:0050681=PMID:15572661, GO:0000079=PMID:7533895, GO:0005739=GO_REF:0000052, GO:0000084=Reactome:REACT_899, GO:0005737=GO_REF:0000052, GO:0000082=Reactome:REACT_1783, GO:0000086=Reactome:REACT_2203, GO:0045944=PMID:8692841, GO:0016032=Reactome:REACT_6256, GO:0007050=PMID:15876871, GO:0000080=Reactome:REACT_1590, GO:0008094=PMID:9852112, GO:0003713=PMID:15572661, GO:0006370=Reactome:REACT_1470, GO:0008022=PMID:10801852, GO:0005524=GO_REF:0000037, GO:0008353=PMID:9852112, GO:0050434=Reactome:REACT_6162, GO:0006281=Reactome:REACT_216, GO:0004672=PMID:9852112, GO:0006283=Reactome:REACT_1628, GO:0004674=GO_REF:0000002, GO:0005654=Reactome:REACT_9070, GO:0006289=Reactome:REACT_1826, GO:0000278=Reactome:REACT_152, GO:0045893=PMID:15572661, GO:0000718=Reactome:REACT_311, GO:0005675=PMID:9852112, GO:0030521=PMID:15572661, GO:0004693=GO_REF:0000003, GO:0051301=GO_REF:0000037} P50613 Cyclin-dependent kinase 7 protein 20101115 {GO:0022415=TAS, GO:0010467=TAS, GO:0006368=TAS, GO:0048471=IEA, GO:0006367=TAS, GO:0006366=TAS, GO:0008283=TAS, GO:0006363=TAS, GO:0006362=TAS, GO:0006361=TAS, GO:0006360=TAS, GO:0005634=IDA, GO:0050681=NAS, GO:0000079=TAS, GO:0005739=IDA, GO:0000084=TAS, GO:0005737=IDA, GO:0000082=TAS, GO:0000086=TAS, GO:0045944=IDA, GO:0016032=TAS, GO:0007050=TAS, GO:0000080=TAS, GO:0008094=IDA, GO:0003713=NAS, GO:0006370=TAS, GO:0008022=IPI, GO:0005524=IEA, GO:0008353=IDA, GO:0050434=TAS, GO:0006281=TAS, GO:0004672=IDA, GO:0006283=TAS, GO:0004674=IEA, GO:0005654=TAS, GO:0006289=TAS, GO:0000278=TAS, GO:0045893=NAS, GO:0000718=TAS, GO:0005675=IDA, GO:0030521=NAS, GO:0004693=IEA, GO:0051301=IEA} 7-methylguanosine mRNA capping, DNA repair, G1 phase of mitotic cell cycle, G1/S transition of mitotic cell cycle, G2/M transition of mitotic cell cycle, S phase of mitotic cell cycle, androgen receptor signaling pathway, cell cycle arrest, cell division, cell proliferation, gene expression, mitotic cell cycle, nucleotide-excision repair, nucleotide-excision repair, DNA damage removal, positive regulation of transcription from RNA polymerase II promoter, positive regulation of transcription, DNA-dependent, positive regulation of viral transcription, regulation of cyclin-dependent protein serine/threonine kinase activity, termination of RNA polymerase I transcription, transcription elongation from RNA polymerase I promoter, transcription elongation from RNA polymerase II promoter, transcription from RNA polymerase I promoter, transcription from RNA polymerase II promoter, transcription initiation from RNA polymerase I promoter, transcription initiation from RNA polymerase II promoter, transcription-coupled nucleotide-excision repair, viral reproduction, viral reproductive process cytoplasm, holo TFIIH complex, mitochondrion, nucleoplasm, nucleus, perinuclear region of cytoplasm ATP binding, DNA-dependent ATPase activity, RNA polymerase II carboxy-terminal domain kinase activity, androgen receptor binding, cyclin-dependent protein serine/threonine kinase activity, protein C-terminus binding, protein kinase activity, protein serine/threonine kinase activity, transcription coactivator activity Human CDK8 IntAct UniProtKB {GO:0005515=PMID:19914168, GO:0010467=Reactome:REACT_71, GO:0006367=Reactome:REACT_12627, GO:0005634=PMID:16109376, GO:0005524=GO_REF:0000037, GO:0008353=GO_REF:0000003, GO:0006351=Reactome:REACT_121061, GO:0004672=PMID:7568034, GO:0007219=Reactome:REACT_118859, GO:0045944=Reactome:REACT_120734, GO:0016592=PMID:14638676, GO:0005654=Reactome:REACT_160249, GO:0007179=Reactome:REACT_6844, GO:0004693=GO_REF:0000003} P49336 Cyclin-dependent kinase 8 protein 20130415 {GO:0005515=IPI, GO:0010467=TAS, GO:0006367=TAS, GO:0005634=IDA, GO:0005524=IEA, GO:0008353=IEA, GO:0006351=TAS, GO:0004672=TAS, GO:0007219=TAS, GO:0045944=TAS, GO:0016592=IDA, GO:0005654=TAS, GO:0007179=TAS, GO:0004693=IEA} Notch signaling pathway, gene expression, positive regulation of transcription from RNA polymerase II promoter, transcription initiation from RNA polymerase II promoter, transcription, DNA-dependent, transforming growth factor beta receptor signaling pathway mediator complex, nucleoplasm, nucleus ATP binding, RNA polymerase II carboxy-terminal domain kinase activity, cyclin-dependent protein serine/threonine kinase activity, protein binding, protein kinase activity Human UniProtKB:P24863 CDK9 HPA UniProtKB {GO:0005515=PMID:23455922, GO:0022415=Reactome:REACT_6361, GO:0010467=Reactome:REACT_71, GO:0071157=PMID:20930849, GO:0006368=Reactome:REACT_1845, GO:0006367=Reactome:REACT_12627, GO:0044212=GO_REF:0000019, GO:0006366=Reactome:REACT_1366, GO:0008283=PMID:8170997, GO:0005634=GO_REF:0000052, GO:0043231=GO_REF:0000052, GO:0005737=GO_REF:0000039, GO:0045944=Reactome:REACT_120734, GO:0016032=Reactome:REACT_6256, GO:0007179=Reactome:REACT_6844, GO:0008024=PMID:15905409, GO:0005730=GO_REF:0000052, GO:0031056=PMID:19844166, GO:0008353=PMID:12721286, GO:0005524=GO_REF:0000037, GO:0008023=PMID:10866664, GO:0003677=PMID:16109376, GO:0006351=Reactome:REACT_121061, GO:0050434=Reactome:REACT_6162, GO:0006281=GO_REF:0000037, GO:0004672=PMID:8170997, GO:0006282=PMID:20493174, GO:0071345=PMID:17956865, GO:0016605=PMID:18250157, GO:0017069=GO_REF:0000019, GO:0006468=PMID:16109376, GO:0005654=Reactome:REACT_121336, GO:0043111=PMID:20930849, GO:0004693=GO_REF:0000003} P50750 Cyclin-dependent kinase 9 protein 20080818 {GO:0005515=IPI, GO:0022415=TAS, GO:0010467=TAS, GO:0071157=IDA, GO:0006368=TAS, GO:0006367=TAS, GO:0044212=IEA, GO:0006366=TAS, GO:0008283=TAS, GO:0005634=IDA, GO:0043231=IDA, GO:0005737=IEA, GO:0045944=TAS, GO:0016032=TAS, GO:0007179=TAS, GO:0008024=IDA, GO:0005730=IDA, GO:0031056=IDA, GO:0008353=IDA, GO:0005524=IEA, GO:0008023=TAS, GO:0003677=IDA, GO:0006351=TAS, GO:0050434=TAS, GO:0006281=IEA, GO:0004672=TAS, GO:0006282=IDA, GO:0071345=IDA, GO:0016605=IDA, GO:0017069=IEA, GO:0006468=IDA, GO:0005654=TAS, GO:0043111=IDA, GO:0004693=IEA} DNA repair, cell proliferation, cellular response to cytokine stimulus, gene expression, negative regulation of cell cycle arrest, positive regulation of transcription from RNA polymerase II promoter, positive regulation of viral transcription, protein phosphorylation, regulation of DNA repair, regulation of histone modification, replication fork arrest, transcription elongation from RNA polymerase II promoter, transcription from RNA polymerase II promoter, transcription initiation from RNA polymerase II promoter, transcription, DNA-dependent, transforming growth factor beta receptor signaling pathway, viral reproduction, viral reproductive process PML body, cytoplasm, intracellular membrane-bounded organelle, nucleolus, nucleoplasm, nucleus, positive transcription elongation factor complex b, transcription elongation factor complex ATP binding, DNA binding, RNA polymerase II carboxy-terminal domain kinase activity, cyclin-dependent protein serine/threonine kinase activity, protein binding, protein kinase activity, snRNA binding, transcription regulatory region DNA binding Human CDKAL1 BHF-UCL UniProtKB {GO:0008150=GO_REF:0000015, GO:0003674=GO_REF:0000015, GO:0051539=GO_REF:0000037, GO:0005789=GO_REF:0000039, GO:0009451=GO_REF:0000002, GO:0005575=GO_REF:0000015, GO:0016021=GO_REF:0000037, GO:0046872=GO_REF:0000037, GO:0016740=GO_REF:0000037, GO:0008033=GO_REF:0000037} Q5VV42 Threonylcarbamoyladenosine tRNA methylthiotransferase protein 20080225 {GO:0008150=ND, GO:0003674=ND, GO:0051539=IEA, GO:0005789=IEA, GO:0009451=IEA, GO:0005575=ND, GO:0016021=IEA, GO:0046872=IEA, GO:0016740=IEA, GO:0008033=IEA} RNA modification, biological_process, tRNA processing cellular_component, endoplasmic reticulum membrane, integral to membrane 4 iron, 4 sulfur cluster binding, metal ion binding, molecular_function, transferase activity Human CDKL1 PINC UniProtKB {GO:0007507=GO_REF:0000019, GO:0005737=GO_REF:0000039, GO:0004672=GO_REF:0000002, GO:0004674=GO_REF:0000002, GO:0006468=PMID:1639063, GO:0005634=GO_REF:0000039, GO:0005524=GO_REF:0000037, GO:0004693=GO_REF:0000003} Q00532 Cyclin-dependent kinase-like 1 protein 20030904 {GO:0007507=IEA, GO:0005737=IEA, GO:0004672=IEA, GO:0004674=IEA, GO:0006468=TAS, GO:0005634=IEA, GO:0005524=IEA, GO:0004693=IEA} heart development, protein phosphorylation cytoplasm, nucleus ATP binding, cyclin-dependent protein serine/threonine kinase activity, protein kinase activity, protein serine/threonine kinase activity Human CDKL2 HPA UniProtKB {GO:0007165=PMID:9000130, GO:0005813=GO_REF:0000052, GO:0005737=GO_REF:0000039, GO:0004672=PMID:9000130, GO:0004674=GO_REF:0000002, GO:0005634=GO_REF:0000052, GO:0007548=PMID:9000130, GO:0005524=GO_REF:0000037, GO:0004693=GO_REF:0000003} Q92772 Cyclin-dependent kinase-like 2 protein 20110516 {GO:0007165=TAS, GO:0005813=IDA, GO:0005737=IEA, GO:0004672=TAS, GO:0004674=IEA, GO:0005634=IDA, GO:0007548=TAS, GO:0005524=IEA, GO:0004693=IEA} sex differentiation, signal transduction centrosome, cytoplasm, nucleus ATP binding, cyclin-dependent protein serine/threonine kinase activity, protein kinase activity, protein serine/threonine kinase activity Human CDKL3 PINC UniProtKB {GO:0005737=GO_REF:0000039, GO:0004672=PMID:10463609, GO:0004674=GO_REF:0000002, GO:0016301=GO_REF:0000038, GO:0005524=GO_REF:0000037, GO:0006464=PMID:10463609, GO:0004693=GO_REF:0000003} Q8IVW4 Cyclin-dependent kinase-like 3 protein 20061106 {GO:0005737=IEA, GO:0004672=TAS, GO:0004674=IEA, GO:0016301=IEA, GO:0005524=IEA, GO:0006464=TAS, GO:0004693=IEA} cellular protein modification process cytoplasm ATP binding, cyclin-dependent protein serine/threonine kinase activity, kinase activity, protein kinase activity, protein serine/threonine kinase activity Human CDKL5 HPA UniProtKB {GO:0005730=GO_REF:0000052, GO:0045773=GO_REF:0000024, GO:0032839=GO_REF:0000024, GO:0032587=GO_REF:0000024, GO:0005634=GO_REF:0000052, GO:0044294=GO_REF:0000024, GO:0005524=PMID:16935860, GO:0032855=GO_REF:0000024, GO:0048365=GO_REF:0000024, GO:0005737=GO_REF:0000052, GO:0004672=PMID:16935860, GO:0046777=PMID:16935860, GO:0004674=PMID:9721213, GO:0016301=PMID:15917271, GO:0050775=GO_REF:0000024, GO:0050773=GO_REF:0000024, GO:0006468=PMID:9721213, GO:0001764=GO_REF:0000024, GO:0004693=GO_REF:0000003} O76039 Cyclin-dependent kinase-like 5 protein 20101115 {GO:0005730=IDA, GO:0045773=ISS, GO:0032839=ISS, GO:0032587=ISS, GO:0005634=IDA, GO:0044294=ISS, GO:0005524=IDA, GO:0032855=ISS, GO:0048365=ISS, GO:0005737=IDA, GO:0004672=IDA, GO:0046777=IDA, GO:0004674=TAS, GO:0016301=IDA, GO:0050775=ISS, GO:0050773=ISS, GO:0006468=TAS, GO:0001764=ISS, GO:0004693=IEA} neuron migration, positive regulation of Rac GTPase activity, positive regulation of axon extension, positive regulation of dendrite morphogenesis, protein autophosphorylation, protein phosphorylation, regulation of dendrite development cytoplasm, dendrite cytoplasm, dendritic growth cone, nucleolus, nucleus, ruffle membrane ATP binding, Rac GTPase binding, cyclin-dependent protein serine/threonine kinase activity, kinase activity, protein kinase activity, protein serine/threonine kinase activity Human CDKN1A BHF-UCL UniProtKB {GO:0005515=PMID:15232106, GO:0030308=PMID:10208428, GO:0046685=GO_REF:0000019, GO:0008285=PMID:18850004, GO:0030890=GO_REF:0000019, GO:0045736=GO_REF:0000019, GO:0019912=PMID:9106657, GO:0031100=GO_REF:0000019, GO:0007265=PMID:9054499, GO:0005634=PMID:11343236, GO:0048146=PMID:17420273, GO:0000079=PMID:8242751, GO:0090400=PMID:20160708, GO:0032403=GO_REF:0000019, GO:0046872=GO_REF:0000037, GO:0005829=Reactome:REACT_9068, GO:0000084=Reactome:REACT_899, GO:0000082=PMID:10208428, GO:0043068=GO_REF:0000019, GO:0031668=PMID:17553787, GO:0000086=PMID:17553787, GO:0070557=PMID:18794347, GO:0033158=GO_REF:0000019, GO:0007050=PMID:17553787, GO:0000080=Reactome:REACT_1590, GO:0009411=GO_REF:0000019, GO:0006977=PMID:15149599, GO:0051412=GO_REF:0000019, GO:0043066=GO_REF:0000019, GO:0030332=GO_REF:0000019, GO:0042493=GO_REF:0000019, GO:0010243=GO_REF:0000019, GO:0009636=GO_REF:0000019, GO:0071479=PMID:20160708, GO:0006974=PMID:20160708, GO:0097193=PMID:9660939, GO:0042326=PMID:10208428, GO:0071850=GO_REF:0000019, GO:0000307=PMID:17420273, GO:0010629=GO_REF:0000019, GO:0055093=GO_REF:0000019, GO:0004861=GO_REF:0000019, GO:0000075=Reactome:REACT_1538, GO:0005654=Reactome:REACT_111248, GO:0000278=Reactome:REACT_152, GO:2000379=PMID:20160708, GO:2000278=GO_REF:0000019, GO:0090398=PMID:15149599} P38936 Cyclin-dependent kinase inhibitor 1 protein 20090804 {GO:0005515=IPI, GO:0030308=IDA, GO:0046685=IEA, GO:0008285=IMP, GO:0030890=IEA, GO:0045736=IEA, GO:0019912=IDA, GO:0031100=IEA, GO:0007265=IEP, GO:0005634=IDA, GO:0048146=IMP, GO:0000079=TAS, GO:0090400=TAS, GO:0032403=IEA, GO:0046872=IEA, GO:0005829=TAS, GO:0000084=TAS, GO:0000082=IDA, GO:0043068=IEA, GO:0031668=IMP, GO:0000086=IMP, GO:0070557=IDA, GO:0033158=IEA, GO:0007050=IMP, GO:0000080=TAS, GO:0009411=IEA, GO:0006977=IDA, GO:0051412=IEA, GO:0043066=IEA, GO:0030332=IEA, GO:0042493=IEA, GO:0010243=IEA, GO:0009636=IEA, GO:0071479=IMP, GO:0006974=IMP, GO:0097193=TAS, GO:0042326=IDA, GO:0071850=IEA, GO:0000307=IDA, GO:0010629=IEA, GO:0055093=IEA, GO:0004861=IEA, GO:0000075=TAS, GO:0005654=TAS, GO:0000278=TAS, GO:2000379=IMP, GO:2000278=IEA, GO:0090398=IMP} DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest, G1 phase of mitotic cell cycle, G1/S transition of mitotic cell cycle, G2/M transition of mitotic cell cycle, Ras protein signal transduction, S phase of mitotic cell cycle, cell cycle arrest, cell cycle checkpoint, cellular response to extracellular stimulus, cellular response to ionizing radiation, cellular senescence, intrinsic apoptotic signaling pathway, mitotic cell cycle, mitotic cell cycle arrest, negative regulation of apoptotic process, negative regulation of cell growth, negative regulation of cell proliferation, negative regulation of cyclin-dependent protein serine/threonine kinase activity, negative regulation of gene expression, negative regulation of phosphorylation, organ regeneration, positive regulation of B cell proliferation, positive regulation of fibroblast proliferation, positive regulation of programmed cell death, positive regulation of reactive oxygen species metabolic process, regulation of DNA biosynthetic process, regulation of cyclin-dependent protein serine/threonine kinase activity, regulation of protein import into nucleus, translocation, response to DNA damage stimulus, response to UV, response to arsenic-containing substance, response to corticosterone stimulus, response to drug, response to hyperoxia, response to organic nitrogen, response to toxic substance, stress-induced premature senescence PCNA-p21 complex, cyclin-dependent protein kinase holoenzyme complex, cytosol, nucleoplasm, nucleus cyclin binding, cyclin-dependent protein kinase activating kinase activity, cyclin-dependent protein serine/threonine kinase inhibitor activity, metal ion binding, protein binding, protein complex binding Human CDKN1B BHF-UCL UniProtKB {GO:0060770=GO_REF:0000019, GO:0005515=PMID:23455922, GO:0048102=PMID:12698196, GO:0030308=PMID:10208428, GO:0045732=PMID:19056892, GO:0008284=GO_REF:0000019, GO:0008285=PMID:19838216, GO:0045736=GO_REF:0000019, GO:0007605=GO_REF:0000019, GO:0005634=PMID:11800646, GO:0000079=PMID:8033212, GO:0005829=Reactome:REACT_147868, GO:0000084=Reactome:REACT_899, GO:0000082=PMID:10208428, GO:0005737=PMID:12093740, GO:0007173=Reactome:REACT_9417, GO:0007050=PMID:12093740, GO:0000080=Reactome:REACT_1590, GO:0006813=GO_REF:0000019, GO:0010942=PMID:19266349, GO:0071236=GO_REF:0000019, GO:0006977=Reactome:REACT_1625, GO:0071285=PMID:19056892, GO:0033673=PMID:19170105, GO:0043066=GO_REF:0000019, GO:0031116=GO_REF:0000019, GO:0048011=Reactome:REACT_11061, GO:0048839=GO_REF:0000019, GO:0006919=PMID:19266349, GO:0019903=PMID:19838216, GO:0048015=Reactome:REACT_12464, GO:0006917=PMID:10208428, GO:0008656=PMID:19266349, GO:0042326=PMID:10208428, GO:0005072=PMID:8033212, GO:0071850=PMID:19266349, GO:0071407=GO_REF:0000019, GO:0008543=Reactome:REACT_9470, GO:0045930=PMID:19266349, GO:0045087=Reactome:REACT_6802, GO:0004861=GO_REF:0000019, GO:0000075=Reactome:REACT_1538, GO:0005654=Reactome:REACT_111248, GO:0000278=Reactome:REACT_152, GO:0051271=GO_REF:0000019, GO:0045892=PMID:19170105, GO:0005768=GO_REF:0000039} P46527 Cyclin-dependent kinase inhibitor 1B protein 20071120 {GO:0060770=IEA, GO:0005515=IPI, GO:0048102=IDA, GO:0030308=IDA, GO:0045732=IDA, GO:0008284=IEA, GO:0008285=IMP, GO:0045736=IEA, GO:0007605=IEA, GO:0005634=IDA, GO:0000079=TAS, GO:0005829=TAS, GO:0000084=TAS, GO:0000082=IDA, GO:0005737=IDA, GO:0007173=TAS, GO:0007050=IMP, GO:0000080=TAS, GO:0006813=IEA, GO:0010942=IDA, GO:0071236=IEA, GO:0006977=TAS, GO:0071285=IDA, GO:0033673=IDA, GO:0043066=IEA, GO:0031116=IEA, GO:0048011=TAS, GO:0048839=IEA, GO:0006919=IDA, GO:0019903=IPI, GO:0048015=TAS, GO:0006917=IDA, GO:0008656=IDA, GO:0042326=IDA, GO:0005072=TAS, GO:0071850=IDA, GO:0071407=IEA, GO:0008543=TAS, GO:0045930=IDA, GO:0045087=TAS, GO:0004861=IEA, GO:0000075=TAS, GO:0005654=TAS, GO:0000278=TAS, GO:0051271=IEA, GO:0045892=IDA, GO:0005768=IEA} DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest, G1 phase of mitotic cell cycle, G1/S transition of mitotic cell cycle, S phase of mitotic cell cycle, activation of cysteine-type endopeptidase activity involved in apoptotic process, autophagic cell death, cell cycle arrest, cell cycle checkpoint, cellular response to antibiotic, cellular response to lithium ion, cellular response to organic cyclic compound, epidermal growth factor receptor signaling pathway, fibroblast growth factor receptor signaling pathway, induction of apoptosis, innate immune response, inner ear development, mitotic cell cycle, mitotic cell cycle arrest, negative regulation of apoptotic process, negative regulation of cell growth, negative regulation of cell proliferation, negative regulation of cellular component movement, negative regulation of cyclin-dependent protein serine/threonine kinase activity, negative regulation of epithelial cell proliferation involved in prostate gland development, negative regulation of kinase activity, negative regulation of mitotic cell cycle, negative regulation of phosphorylation, negative regulation of transcription, DNA-dependent, neurotrophin TRK receptor signaling pathway, phosphatidylinositol-mediated signaling, positive regulation of cell death, positive regulation of cell proliferation, positive regulation of microtubule polymerization, positive regulation of protein catabolic process, potassium ion transport, regulation of cyclin-dependent protein serine/threonine kinase activity, sensory perception of sound cytoplasm, cytosol, endosome, nucleoplasm, nucleus cyclin-dependent protein serine/threonine kinase inhibitor activity, cysteine-type endopeptidase activator activity involved in apoptotic process, protein binding, protein phosphatase binding, transforming growth factor beta receptor, cytoplasmic mediator activity Human CDKN1C HPA UniProtKB {GO:0005515=PMID:22634751, GO:0033673=PMID:19170105, GO:0008285=PMID:7729684, GO:0042551=GO_REF:0000019, GO:0005730=GO_REF:0000052, GO:0050680=PMID:16943770, GO:0005634=GO_REF:0000052, GO:0000122=GO_REF:0000019, GO:0001890=GO_REF:0000019, GO:0000079=PMID:7729684, GO:0042326=PMID:19170105, GO:0005737=GO_REF:0000052, GO:0004861=GO_REF:0000002, GO:0007050=GO_REF:0000002, GO:0045893=PMID:19170105, GO:0000080=PMID:7729684, GO:0045892=PMID:19170105, GO:0030511=PMID:16943770} P49918 Cyclin-dependent kinase inhibitor 1C protein 20080205 {GO:0005515=IPI, GO:0033673=IDA, GO:0008285=TAS, GO:0042551=IEA, GO:0005730=IDA, GO:0050680=IMP, GO:0005634=IDA, GO:0000122=IEA, GO:0001890=IEA, GO:0000079=TAS, GO:0042326=IDA, GO:0005737=IDA, GO:0004861=IEA, GO:0007050=IEA, GO:0045893=IGI, GO:0000080=TAS, GO:0045892=IDA, GO:0030511=IMP} G1 phase of mitotic cell cycle, cell cycle arrest, negative regulation of cell proliferation, negative regulation of epithelial cell proliferation, negative regulation of kinase activity, negative regulation of phosphorylation, negative regulation of transcription from RNA polymerase II promoter, negative regulation of transcription, DNA-dependent, neuron maturation, placenta development, positive regulation of transcription, DNA-dependent, positive regulation of transforming growth factor beta receptor signaling pathway, regulation of cyclin-dependent protein serine/threonine kinase activity cytoplasm, nucleolus, nucleus cyclin-dependent protein serine/threonine kinase inhibitor activity, protein binding Human CDKN2A BHF-UCL UniProtKB {GO:0005515=PMID:17486078, GO:0033088=GO_REF:0000024, GO:0030308=PMID:10208428, GO:0006364=GO_REF:0000037, GO:0035985=PMID:16901784, GO:0035986=PMID:16901784, GO:0070534=PMID:18305112, GO:0008637=PMID:12082630, GO:0016301=GO_REF:0000038, GO:0051444=GO_REF:0000024, GO:0055105=GO_REF:0000024, GO:0000209=PMID:18305112, GO:0019901=PMID:8259215, GO:0010389=PMID:15582998, GO:0030889=GO_REF:0000024, GO:0000075=PMID:16243918, GO:0005654=PMID:17110379, GO:0000278=Reactome:REACT_152, GO:0090399=PMID:14720514, GO:0045893=PMID:17569660, GO:0045892=PMID:16901784, GO:0008134=PMID:19057511, GO:0001953=PMID:10205165, GO:0090398=PMID:14966292, GO:0048103=GO_REF:0000024, GO:0008285=PMID:17569660, GO:0045736=PMID:8259215, GO:0007265=PMID:9054499, GO:0005634=PMID:11800646, GO:0005829=Reactome:REACT_7947, GO:0005739=GO_REF:0000039, GO:0031648=PMID:9529249, GO:0000082=PMID:10208428, GO:0005737=PMID:16243918, GO:0031647=GO_REF:0000024, GO:0045944=PMID:17569660, GO:0033235=PMID:19057511, GO:2000774=PMID:16901784, GO:0007050=PMID:15582998, GO:0000080=Reactome:REACT_1590, GO:0051059=PMID:10353611, GO:0006919=PMID:12082630, GO:0005730=PMID:17110379, GO:0032088=PMID:10353611, GO:0006917=PMID:12082630, GO:2000111=PMID:20381282, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037, GO:0042326=PMID:8259215, GO:0006309=PMID:12082630, GO:0034393=PMID:20381282, GO:0004861=PMID:8259215, GO:0006469=PMID:15582998} Q8N726 Cyclin-dependent kinase inhibitor 2A, isoform 4 protein 20071114 {GO:0005515=IPI, GO:0033088=ISS, GO:0030308=IDA, GO:0006364=IEA, GO:0035985=IDA, GO:0035986=IMP, GO:0070534=IDA, GO:0008637=IMP, GO:0016301=IEA, GO:0051444=ISS, GO:0055105=ISS, GO:0000209=IDA, GO:0019901=IPI, GO:0010389=IMP, GO:0030889=ISS, GO:0000075=IMP, GO:0005654=IDA, GO:0000278=TAS, GO:0090399=IMP, GO:0045893=IDA, GO:0045892=IMP, GO:0008134=IPI, GO:0001953=IMP, GO:0090398=IMP, GO:0048103=ISS, GO:0008285=IDA, GO:0045736=IDA, GO:0007265=IEP, GO:0005634=IDA, GO:0005829=TAS, GO:0005739=IEA, GO:0031648=IDA, GO:0000082=IDA, GO:0005737=IDA, GO:0031647=ISS, GO:0045944=IDA, GO:0033235=IMP, GO:2000774=IMP, GO:0007050=IMP, GO:0000080=TAS, GO:0051059=IDA, GO:0006919=IMP, GO:0005730=IDA, GO:0032088=IDA, GO:0006917=IMP, GO:2000111=ISS, GO:0003677=IEA, GO:0006351=IEA, GO:0042326=IDA, GO:0006309=IMP, GO:0034393=ISS, GO:0004861=IDA, GO:0006469=IMP} G1 phase of mitotic cell cycle, G1/S transition of mitotic cell cycle, Ras protein signal transduction, activation of cysteine-type endopeptidase activity involved in apoptotic process, apoptotic DNA fragmentation, apoptotic mitochondrial changes, cell cycle arrest, cell cycle checkpoint, cellular senescence, induction of apoptosis, mitotic cell cycle, negative regulation of B cell proliferation, negative regulation of NF-kappaB transcription factor activity, negative regulation of cell growth, negative regulation of cell proliferation, negative regulation of cell-matrix adhesion, negative regulation of cyclin-dependent protein serine/threonine kinase activity, negative regulation of immature T cell proliferation in thymus, negative regulation of phosphorylation, negative regulation of protein kinase activity, negative regulation of transcription, DNA-dependent, negative regulation of ubiquitin-protein ligase activity, positive regulation of cellular senescence, positive regulation of macrophage apoptotic process, positive regulation of protein sumoylation, positive regulation of smooth muscle cell apoptotic process, positive regulation of transcription from RNA polymerase II promoter, positive regulation of transcription, DNA-dependent, protein K63-linked ubiquitination, protein destabilization, protein polyubiquitination, rRNA processing, regulation of G2/M transition of mitotic cell cycle, regulation of protein stability, replicative senescence, senescence-associated heterochromatin focus assembly, somatic stem cell division, transcription, DNA-dependent cytoplasm, cytosol, mitochondrion, nucleolus, nucleoplasm, nucleus, senescence-associated heterochromatin focus DNA binding, NF-kappaB binding, cyclin-dependent protein serine/threonine kinase inhibitor activity, kinase activity, protein binding, protein kinase binding, transcription factor binding, ubiquitin-protein ligase inhibitor activity Human CDKN2AIP BHF-UCL UniProtKB {GO:0005515=PMID:12581788, GO:0003725=GO_REF:0000002, GO:0002039=PMID:15109303, GO:0030308=PMID:15109303, GO:0031647=PMID:12154087, GO:0001652=PMID:12154087, GO:0005730=PMID:12154087, GO:0009967=PMID:15109303, GO:0005654=PMID:12154087} Q9NXV6 CDKN2A-interacting protein protein 20090630 {GO:0005515=IPI, GO:0003725=IEA, GO:0002039=IDA, GO:0030308=IMP, GO:0031647=IMP, GO:0001652=IDA, GO:0005730=IDA, GO:0009967=IMP, GO:0005654=IDA} negative regulation of cell growth, positive regulation of signal transduction, regulation of protein stability granular component, nucleolus, nucleoplasm double-stranded RNA binding, p53 binding, protein binding Human CDKN2AIPNL null null {} null null null null {} null null null CDKN2B BHF-UCL UniProtKB {GO:0031670=PMID:17597576, GO:0005515=PMID:23455922, GO:0014070=GO_REF:0000019, GO:0010467=Reactome:REACT_71, GO:0007093=PMID:17553787, GO:0006367=Reactome:REACT_12627, GO:0008285=PMID:17553787, GO:0050680=PMID:16943770, GO:0005634=PMID:18564286, GO:0000079=PMID:8078588, GO:0005829=Reactome:REACT_120757, GO:0005737=PMID:16943770, GO:0030858=GO_REF:0000019, GO:0000086=PMID:17553787, GO:0045944=Reactome:REACT_120734, GO:0031668=PMID:17553787, GO:0007179=Reactome:REACT_6844, GO:0007050=PMID:17553787, GO:0034097=GO_REF:0000019, GO:0000080=Reactome:REACT_1590, GO:0030511=PMID:16943770, GO:0019901=PMID:8078588, GO:0006351=Reactome:REACT_121061, GO:0042326=PMID:8078588, GO:0030219=PMID:10812241, GO:0004861=PMID:8078588, GO:0000278=Reactome:REACT_152} P42772 Cyclin-dependent kinase 4 inhibitor B protein 20071120 {GO:0031670=IMP, GO:0005515=IPI, GO:0014070=IEA, GO:0010467=TAS, GO:0007093=IMP, GO:0006367=TAS, GO:0008285=IMP, GO:0050680=IMP, GO:0005634=IDA, GO:0000079=IDA, GO:0005829=TAS, GO:0005737=IDA, GO:0030858=IEA, GO:0000086=IMP, GO:0045944=TAS, GO:0031668=IMP, GO:0007179=TAS, GO:0007050=IMP, GO:0034097=IEA, GO:0000080=TAS, GO:0030511=IMP, GO:0019901=IPI, GO:0006351=TAS, GO:0042326=IDA, GO:0030219=IEP, GO:0004861=IDA, GO:0000278=TAS} G1 phase of mitotic cell cycle, G2/M transition of mitotic cell cycle, cell cycle arrest, cellular response to extracellular stimulus, cellular response to nutrient, gene expression, megakaryocyte differentiation, mitotic cell cycle, mitotic cell cycle checkpoint, negative regulation of cell proliferation, negative regulation of epithelial cell proliferation, negative regulation of phosphorylation, positive regulation of epithelial cell differentiation, positive regulation of transcription from RNA polymerase II promoter, positive regulation of transforming growth factor beta receptor signaling pathway, regulation of cyclin-dependent protein serine/threonine kinase activity, response to cytokine stimulus, response to organic cyclic compound, transcription initiation from RNA polymerase II promoter, transcription, DNA-dependent, transforming growth factor beta receptor signaling pathway cytoplasm, cytosol, nucleus cyclin-dependent protein serine/threonine kinase inhibitor activity, protein binding, protein kinase binding Human CDKN2C BHF-UCL UniProtKB {GO:0030308=PMID:10208428, GO:0008285=PMID:10208428, GO:0019901=PMID:8001816, GO:0048709=GO_REF:0000019, GO:0005634=PMID:11800646, GO:0006917=PMID:10208428, GO:0000079=PMID:8001816, GO:0005829=Reactome:REACT_7947, GO:0042326=PMID:10208428, GO:0000082=PMID:10208428, GO:0005737=PMID:11800646, GO:0004861=PMID:8001816, GO:0007050=PMID:10208428, GO:0000080=Reactome:REACT_1590, GO:0000278=Reactome:REACT_152} P42773 Cyclin-dependent kinase 4 inhibitor C protein 20071120 {GO:0030308=IDA, GO:0008285=IDA, GO:0019901=IPI, GO:0048709=IEA, GO:0005634=IDA, GO:0006917=IDA, GO:0000079=IDA, GO:0005829=TAS, GO:0042326=IDA, GO:0000082=IDA, GO:0005737=IDA, GO:0004861=IDA, GO:0007050=IDA, GO:0000080=TAS, GO:0000278=TAS} G1 phase of mitotic cell cycle, G1/S transition of mitotic cell cycle, cell cycle arrest, induction of apoptosis, mitotic cell cycle, negative regulation of cell growth, negative regulation of cell proliferation, negative regulation of phosphorylation, oligodendrocyte differentiation, regulation of cyclin-dependent protein serine/threonine kinase activity cytoplasm, cytosol, nucleus cyclin-dependent protein serine/threonine kinase inhibitor activity, protein kinase binding Human UniProtKB:Q00534 CDKN2D BHF-UCL UniProtKB {GO:0043066=PMID:15750620, GO:0048102=PMID:16322758, GO:0030308=PMID:10208428, GO:0008285=PMID:10208428, GO:0019901=PMID:8741839, GO:0007605=GO_REF:0000019, GO:0033280=PMID:16322758, GO:0005634=PMID:15750620, GO:0000079=PMID:8741839, GO:0005829=Reactome:REACT_7947, GO:0042326=PMID:10208428, GO:0005737=PMID:15750620, GO:0000082=PMID:10208428, GO:0000731=PMID:15750620, GO:0004861=PMID:8741839, GO:0007050=PMID:10208428, GO:0032526=PMID:16322758, GO:0043154=PMID:15750620, GO:0000080=Reactome:REACT_1590, GO:0000278=Reactome:REACT_152, GO:0009411=PMID:15750620} P55273 Cyclin-dependent kinase 4 inhibitor D protein 20071121 {GO:0043066=IMP, GO:0048102=IMP, GO:0030308=IDA, GO:0008285=IDA, GO:0019901=IPI, GO:0007605=IEA, GO:0033280=IMP, GO:0005634=IDA, GO:0000079=IDA, GO:0005829=TAS, GO:0042326=IDA, GO:0005737=IDA, GO:0000082=IDA, GO:0000731=IMP, GO:0004861=IDA, GO:0007050=IDA, GO:0032526=IMP, GO:0043154=IMP, GO:0000080=TAS, GO:0000278=TAS, GO:0009411=IMP} DNA synthesis involved in DNA repair, G1 phase of mitotic cell cycle, G1/S transition of mitotic cell cycle, autophagic cell death, cell cycle arrest, mitotic cell cycle, negative regulation of apoptotic process, negative regulation of cell growth, negative regulation of cell proliferation, negative regulation of cysteine-type endopeptidase activity involved in apoptotic process, negative regulation of phosphorylation, regulation of cyclin-dependent protein serine/threonine kinase activity, response to UV, response to retinoic acid, response to vitamin D, sensory perception of sound cytoplasm, cytosol, nucleus cyclin-dependent protein serine/threonine kinase inhibitor activity, protein kinase binding Human CDKN3 GOC UniProtKB {GO:0005515=PMID:11463386, GO:0000082=PMID:8127873, GO:0048471=PMID:10669749, GO:0008285=PMID:8242750, GO:0007050=PMID:8242750, GO:0004722=PMID:12745075, GO:0008138=PMID:8242750, GO:0000079=PMID:8242750, GO:0035335=PMID:8242750, GO:0004725=PMID:8242750} Q16667 Cyclin-dependent kinase inhibitor 3 protein 20130413 {GO:0005515=IPI, GO:0000082=TAS, GO:0048471=IDA, GO:0008285=TAS, GO:0007050=IDA, GO:0004722=IDA, GO:0008138=TAS, GO:0000079=TAS, GO:0035335=IDA, GO:0004725=IDA} G1/S transition of mitotic cell cycle, cell cycle arrest, negative regulation of cell proliferation, peptidyl-tyrosine dephosphorylation, regulation of cyclin-dependent protein serine/threonine kinase activity perinuclear region of cytoplasm protein binding, protein serine/threonine phosphatase activity, protein tyrosine phosphatase activity, protein tyrosine/serine/threonine phosphatase activity Human CDO1 Reactome UniProtKB {GO:0045471=GO_REF:0000019, GO:0006534=PMID:12110289, GO:0051384=GO_REF:0000019, GO:0044281=Reactome:REACT_111217, GO:0051591=GO_REF:0000019, GO:0008198=GO_REF:0000019, GO:0005829=Reactome:REACT_115785, GO:0034641=Reactome:REACT_13, GO:0000096=Reactome:REACT_115639, GO:0006954=PMID:12110289, GO:0007595=GO_REF:0000019, GO:0000097=PMID:12110289, GO:0000098=Reactome:REACT_115654, GO:0033762=GO_REF:0000019, GO:0017172=Reactome:REACT_115785, GO:0042412=PMID:12871209, GO:0019448=GO_REF:0000019, GO:0043200=GO_REF:0000019, GO:0055114=PMID:12110289} Q16878 Cysteine dioxygenase type 1 protein 20110929 {GO:0045471=IEA, GO:0006534=TAS, GO:0051384=IEA, GO:0044281=TAS, GO:0051591=IEA, GO:0008198=IEA, GO:0005829=TAS, GO:0034641=TAS, GO:0000096=TAS, GO:0006954=TAS, GO:0007595=IEA, GO:0000097=TAS, GO:0000098=TAS, GO:0033762=IEA, GO:0017172=TAS, GO:0042412=TAS, GO:0019448=IEA, GO:0043200=IEA, GO:0055114=TAS} L-cysteine catabolic process, cellular nitrogen compound metabolic process, cysteine metabolic process, inflammatory response, lactation, oxidation-reduction process, response to amino acid stimulus, response to cAMP, response to ethanol, response to glucagon stimulus, response to glucocorticoid stimulus, small molecule metabolic process, sulfur amino acid biosynthetic process, sulfur amino acid catabolic process, sulfur amino acid metabolic process, taurine biosynthetic process cytosol cysteine dioxygenase activity, ferrous iron binding Human CDON Reactome UniProtKB {GO:0005515=PMID:11782431, GO:0043497=GO_REF:0000019, GO:2000179=GO_REF:0000019, GO:0010172=GO_REF:0000019, GO:0021987=GO_REF:0000019, GO:0005886=Reactome:REACT_21377, GO:0001708=GO_REF:0000019, GO:0051057=GO_REF:0000019, GO:0007520=GO_REF:0000019, GO:0060059=GO_REF:0000019, GO:0009952=GO_REF:0000019, GO:0048643=GO_REF:0000019, GO:0007224=GO_REF:0000019, GO:0014816=GO_REF:0000019, GO:0042692=Reactome:REACT_21303, GO:0051149=Reactome:REACT_21402, GO:0002088=GO_REF:0000019, GO:0045666=GO_REF:0000019, GO:0045944=GO_REF:0000019, GO:0001934=GO_REF:0000019, GO:0016021=GO_REF:0000037, GO:0007155=PMID:9214393, GO:0043410=GO_REF:0000019} Q4KMG0 Cell adhesion molecule-related/down-regulated by oncogenes protein 20091030 {GO:0005515=IPI, GO:0043497=IEA, GO:2000179=IEA, GO:0010172=IEA, GO:0021987=IEA, GO:0005886=TAS, GO:0001708=IEA, GO:0051057=IEA, GO:0007520=IEA, GO:0060059=IEA, GO:0009952=IEA, GO:0048643=IEA, GO:0007224=IEA, GO:0014816=IEA, GO:0042692=TAS, GO:0051149=TAS, GO:0002088=IEA, GO:0045666=IEA, GO:0045944=IEA, GO:0001934=IEA, GO:0016021=IEA, GO:0007155=TAS, GO:0043410=IEA} anterior/posterior pattern specification, cell adhesion, cell fate specification, cerebral cortex development, embryonic body morphogenesis, embryonic retina morphogenesis in camera-type eye, lens development in camera-type eye, muscle cell differentiation, myoblast fusion, positive regulation of MAPK cascade, positive regulation of muscle cell differentiation, positive regulation of neural precursor cell proliferation, positive regulation of neuron differentiation, positive regulation of protein phosphorylation, positive regulation of skeletal muscle tissue development, positive regulation of small GTPase mediated signal transduction, positive regulation of transcription from RNA polymerase II promoter, regulation of protein heterodimerization activity, satellite cell differentiation, smoothened signaling pathway integral to membrane, plasma membrane protein binding Human CDR2 UniProtKB UniProtKB {GO:0003674=GO_REF:0000015, GO:0005737=GO_REF:0000019, GO:0005634=GO_REF:0000029} Q01850 Cerebellar degeneration-related protein 2 protein 20061026 {GO:0003674=ND, GO:0005737=IEA, GO:0005634=NAS} cytoplasm, nucleus molecular_function Human CDR2L null null {} null null null null {} null null null CDRT15 null null {} null null null null {} null null null CDS1 GOC UniProtKB {GO:0006661=Reactome:REACT_121000, GO:0005783=GO_REF:0000024, GO:0044281=Reactome:REACT_111217, GO:0007165=PMID:9115637, GO:0004605=Reactome:REACT_121066, GO:0016024=PMID:9407135, GO:0005789=Reactome:REACT_121066, GO:0016021=GO_REF:0000037, GO:0004142=PMID:9115637, GO:0007602=PMID:9806839, GO:0006644=Reactome:REACT_120870, GO:0006657=PMID:9115637, GO:0046474=Reactome:REACT_121401} Q92903 Phosphatidate cytidylyltransferase 1 protein 20130413 {GO:0006661=TAS, GO:0005783=ISS, GO:0044281=TAS, GO:0007165=NAS, GO:0004605=TAS, GO:0016024=IDA, GO:0005789=TAS, GO:0016021=IEA, GO:0004142=NAS, GO:0007602=NAS, GO:0006644=TAS, GO:0006657=NAS, GO:0046474=TAS} CDP-choline pathway, CDP-diacylglycerol biosynthetic process, glycerophospholipid biosynthetic process, phosphatidylinositol biosynthetic process, phospholipid metabolic process, phototransduction, signal transduction, small molecule metabolic process endoplasmic reticulum, endoplasmic reticulum membrane, integral to membrane diacylglycerol cholinephosphotransferase activity, phosphatidate cytidylyltransferase activity Human CDS2 Reactome UniProtKB {GO:0005783=GO_REF:0000019, GO:0004605=PMID:9806839, GO:0005743=Reactome:REACT_121008, GO:0016024=GO_REF:0000041, GO:0044281=Reactome:REACT_111217, GO:0008654=GO_REF:0000029, GO:0016021=GO_REF:0000029, GO:0006644=Reactome:REACT_120870, GO:0006655=Reactome:REACT_121280, GO:0046474=Reactome:REACT_121401} O95674 Phosphatidate cytidylyltransferase 2 protein 20130301 {GO:0005783=IEA, GO:0004605=NAS, GO:0005743=TAS, GO:0016024=IEA, GO:0044281=TAS, GO:0008654=NAS, GO:0016021=NAS, GO:0006644=TAS, GO:0006655=TAS, GO:0046474=TAS} CDP-diacylglycerol biosynthetic process, glycerophospholipid biosynthetic process, phosphatidylglycerol biosynthetic process, phospholipid biosynthetic process, phospholipid metabolic process, small molecule metabolic process endoplasmic reticulum, integral to membrane, mitochondrial inner membrane phosphatidate cytidylyltransferase activity Human CDSN MGI UniProtKB {GO:0030057=PMID:11279026, GO:0016337=PMID:11739386, GO:0008544=PMID:9395522, GO:0005911=PMID:9395522, GO:0030216=PMID:8415725, GO:0005576=GO_REF:0000039, GO:0043589=PMID:20691404, GO:0007155=PMID:9395522, GO:0042803=PMID:15086562, GO:0001533=PMID:9395522} Q15517 Corneodesmosin protein 20060111 {GO:0030057=IDA, GO:0016337=IDA, GO:0008544=TAS, GO:0005911=TAS, GO:0030216=NAS, GO:0005576=IEA, GO:0043589=IMP, GO:0007155=TAS, GO:0042803=IDA, GO:0001533=IDA} cell adhesion, cell-cell adhesion, epidermis development, keratinocyte differentiation, skin morphogenesis cell-cell junction, cornified envelope, desmosome, extracellular region protein homodimerization activity Human CDT1 HPA UniProtKB {GO:0005515=PMID:20202939, GO:0005634=GO_REF:0000052, GO:0003677=GO_REF:0000024, GO:0005829=Reactome:REACT_1787, GO:0006260=GO_REF:0000037, GO:0000084=Reactome:REACT_899, GO:0000082=Reactome:REACT_1783, GO:0030174=PMID:11125146, GO:0000083=Reactome:REACT_683, GO:0000076=PMID:14672932, GO:0005654=Reactome:REACT_22145, GO:0007090=GO_REF:0000019, GO:0000278=Reactome:REACT_152} Q9H211 DNA replication factor Cdt1 protein 20101115 {GO:0005515=IPI, GO:0005634=IDA, GO:0003677=ISS, GO:0005829=TAS, GO:0006260=IEA, GO:0000084=TAS, GO:0000082=TAS, GO:0030174=IDA, GO:0000083=TAS, GO:0000076=IDA, GO:0005654=TAS, GO:0007090=IEA, GO:0000278=TAS} DNA replication, DNA replication checkpoint, G1/S transition of mitotic cell cycle, S phase of mitotic cell cycle, mitotic cell cycle, regulation of DNA-dependent DNA replication initiation, regulation of S phase of mitotic cell cycle, regulation of transcription involved in G1/S phase of mitotic cell cycle cytosol, nucleoplasm, nucleus DNA binding, protein binding Human CDV3 HPA UniProtKB {GO:0003674=GO_REF:0000015, GO:0005737=GO_REF:0000052, GO:0008283=PMID:10497265, GO:0005730=GO_REF:0000052, GO:0005575=GO_REF:0000015} Q9UKY7 Protein CDV3 homolog protein 20111111 {GO:0003674=ND, GO:0005737=IDA, GO:0008283=NAS, GO:0005730=IDA, GO:0005575=ND} cell proliferation cellular_component, cytoplasm, nucleolus molecular_function Human CDX1 PINC UniProtKB {GO:0000976=GO_REF:0000002, GO:0003700=GO_REF:0000002, GO:0060349=GO_REF:0000019, GO:0045944=GO_REF:0000019, GO:0009887=PMID:8530027, GO:0005634=GO_REF:0000039, GO:0009952=GO_REF:0000019} P47902 Homeobox protein CDX-1 protein 20031120 {GO:0000976=IEA, GO:0003700=IEA, GO:0060349=IEA, GO:0045944=IEA, GO:0009887=TAS, GO:0005634=IEA, GO:0009952=IEA} anterior/posterior pattern specification, bone morphogenesis, organ morphogenesis, positive regulation of transcription from RNA polymerase II promoter nucleus sequence-specific DNA binding transcription factor activity, transcription regulatory region sequence-specific DNA binding Human CDX2 PINC UniProtKB {GO:0060711=GO_REF:0000019, GO:0000976=GO_REF:0000002, GO:0000794=GO_REF:0000019, GO:0003700=GO_REF:0000002, GO:0001568=GO_REF:0000019, GO:0006366=PMID:9459001, GO:0003714=GO_REF:0000019, GO:0045597=GO_REF:0000019, GO:0008333=GO_REF:0000019, GO:0005634=GO_REF:0000040, GO:0000122=GO_REF:0000019, GO:0001829=GO_REF:0000019, GO:0009952=GO_REF:0000019, GO:0045197=GO_REF:0000019, GO:0017053=GO_REF:0000019, GO:0009887=PMID:9052785, GO:0035019=GO_REF:0000019} Q99626 Homeobox protein CDX-2 protein 20031120 {GO:0060711=IEA, GO:0000976=IEA, GO:0000794=IEA, GO:0003700=IEA, GO:0001568=IEA, GO:0006366=TAS, GO:0003714=IEA, GO:0045597=IEA, GO:0008333=IEA, GO:0005634=IEA, GO:0000122=IEA, GO:0001829=IEA, GO:0009952=IEA, GO:0045197=IEA, GO:0017053=IEA, GO:0009887=TAS, GO:0035019=IEA} anterior/posterior pattern specification, blood vessel development, endosome to lysosome transport, establishment or maintenance of epithelial cell apical/basal polarity, labyrinthine layer development, negative regulation of transcription from RNA polymerase II promoter, organ morphogenesis, positive regulation of cell differentiation, somatic stem cell maintenance, transcription from RNA polymerase II promoter, trophectodermal cell differentiation condensed nuclear chromosome, nucleus, transcriptional repressor complex sequence-specific DNA binding transcription factor activity, transcription corepressor activity, transcription regulatory region sequence-specific DNA binding Human CDX4 UniProtKB UniProtKB {GO:0060711=GO_REF:0000019, GO:0000976=GO_REF:0000002, GO:0001568=GO_REF:0000019, GO:0003700=GO_REF:0000002, GO:0005634=GO_REF:0000039, GO:0000122=GO_REF:0000019, GO:0009952=GO_REF:0000019, GO:0006351=GO_REF:0000037} O14627 Homeobox protein CDX-4 protein 20130413 {GO:0060711=IEA, GO:0000976=IEA, GO:0001568=IEA, GO:0003700=IEA, GO:0005634=IEA, GO:0000122=IEA, GO:0009952=IEA, GO:0006351=IEA} anterior/posterior pattern specification, blood vessel development, labyrinthine layer development, negative regulation of transcription from RNA polymerase II promoter, transcription, DNA-dependent nucleus sequence-specific DNA binding transcription factor activity, transcription regulatory region sequence-specific DNA binding Human UniProtKB-SubCell:SL-0191 CDY1 PINC UniProtKB {GO:0005634=GO_REF:0000039, GO:0007283=PMID:9381176, GO:0004402=GO_REF:0000003} Q9Y6F8 Testis-specific chromodomain protein Y 1 protein 20050308 {GO:0005634=IEA, GO:0007283=TAS, GO:0004402=IEA} spermatogenesis nucleus histone acetyltransferase activity Human CDY1B null null {} null null null null {} null null null CDY2A PINC UniProtKB {GO:0005634=GO_REF:0000039, GO:0007283=PMID:9381176, GO:0003824=GO_REF:0000002, GO:0004402=GO_REF:0000003} Q9Y6F7 Testis-specific chromodomain protein Y 2 protein 20030904 {GO:0005634=IEA, GO:0007283=TAS, GO:0003824=IEA, GO:0004402=IEA} spermatogenesis nucleus catalytic activity, histone acetyltransferase activity Human CDY2B null null {} null null null null {} null null null CDYL PINC UniProtKB {GO:0006355=GO_REF:0000037, GO:0005634=PMID:18450745, GO:0007283=PMID:10192397, GO:0035064=PMID:18450745, GO:0003824=GO_REF:0000002, GO:0006351=GO_REF:0000037, GO:0004402=GO_REF:0000003} Q9Y232 Chromodomain Y-like protein protein 20030904 {GO:0006355=IEA, GO:0005634=IDA, GO:0007283=TAS, GO:0035064=IDA, GO:0003824=IEA, GO:0006351=IEA, GO:0004402=IEA} regulation of transcription, DNA-dependent, spermatogenesis, transcription, DNA-dependent nucleus catalytic activity, histone acetyltransferase activity, methylated histone residue binding Human CDYL2 UniProtKB UniProtKB {GO:0005515=PMID:17577209, GO:0005634=GO_REF:0000039, GO:0003824=GO_REF:0000002} Q8N8U2 Chromodomain Y-like protein 2 protein 20090724 {GO:0005515=IPI, GO:0005634=IEA, GO:0003824=IEA} nucleus catalytic activity, protein binding Human UniProtKB:Q9BQA5 CEACAM1 IntAct UniProtKB {GO:0005515=PMID:21982860, GO:0003674=GO_REF:0000015, GO:0005886=Reactome:REACT_12073, GO:0016020=PMID:2457922, GO:0016477=PMID:15687237, GO:0005887=PMID:15687237, GO:0007229=PMID:15687237, GO:0005576=GO_REF:0000039, GO:0016021=PMID:11994468, GO:0001525=PMID:15687237, GO:0007156=PMID:15687237} P13688 Carcinoembryonic antigen-related cell adhesion molecule 1 protein 20130415 {GO:0005515=IPI, GO:0003674=ND, GO:0005886=TAS, GO:0016020=TAS, GO:0016477=NAS, GO:0005887=NAS, GO:0007229=NAS, GO:0005576=IEA, GO:0016021=IDA, GO:0001525=NAS, GO:0007156=NAS} angiogenesis, cell migration, homophilic cell adhesion, integrin-mediated signaling pathway extracellular region, integral to membrane, integral to plasma membrane, membrane, plasma membrane molecular_function, protein binding Human UniProtKB:Q16568 CEACAM21 UniProtKB UniProtKB {GO:0016021=GO_REF:0000037} Q3KPI0 Carcinoembryonic antigen-related cell adhesion molecule 21 protein 20130413 {GO:0016021=IEA} integral to membrane Human UniProtKB-KW:KW-0812 CEACAM3 UniProtKB UniProtKB {GO:0016021=GO_REF:0000037} P40198 Carcinoembryonic antigen-related cell adhesion molecule 3 protein 20130413 {GO:0016021=IEA} integral to membrane Human UniProtKB-KW:KW-0812 CEACAM5 IntAct UniProtKB {GO:0016323=PMID:15052268, GO:0005887=PMID:3814146, GO:0031225=GO_REF:0000037, GO:0042802=PMID:18086185} P06731 Carcinoembryonic antigen-related cell adhesion molecule 5 protein 20130415 {GO:0016323=IDA, GO:0005887=TAS, GO:0031225=IEA, GO:0042802=IPI} anchored to membrane, basolateral plasma membrane, integral to plasma membrane identical protein binding Human UniProtKB:P06731 CEACAM6 IntAct UniProtKB {GO:0005515=PMID:21982860, GO:0007165=PMID:3220478, GO:0005886=Reactome:REACT_12073, GO:0005887=PMID:3220478, GO:0007267=PMID:3220478, GO:0031225=GO_REF:0000037} P40199 Carcinoembryonic antigen-related cell adhesion molecule 6 protein 20130415 {GO:0005515=IPI, GO:0007165=TAS, GO:0005886=TAS, GO:0005887=TAS, GO:0007267=TAS, GO:0031225=IEA} cell-cell signaling, signal transduction anchored to membrane, integral to plasma membrane, plasma membrane protein binding Human UniProtKB:Q16568 CEACAM8 Reactome UniProtKB {GO:0006955=PMID:2208113, GO:0005886=Reactome:REACT_12073, GO:0005887=PMID:2208113, GO:0031225=GO_REF:0000037, GO:0005615=PMID:2306228} P31997 Carcinoembryonic antigen-related cell adhesion molecule 8 protein 20071125 {GO:0006955=TAS, GO:0005886=TAS, GO:0005887=TAS, GO:0031225=IEA, GO:0005615=TAS} immune response anchored to membrane, extracellular space, integral to plasma membrane, plasma membrane Human CEBPA IntAct UniProtKB {GO:0005515=PMID:16490787, GO:0003700=PMID:12695546, GO:0008285=GO_REF:0000019, GO:0006366=PMID:8643605, GO:0044212=PMID:12695546, GO:0030324=GO_REF:0000019, GO:0003705=PMID:7575576, GO:0019221=PMID:15664994, GO:0031100=GO_REF:0000019, GO:0005634=PMID:7575576, GO:0006091=PMID:8643605, GO:0032403=GO_REF:0000019, GO:0016363=GO_REF:0000019, GO:0042803=GO_REF:0000019, GO:0045944=GO_REF:0000019, GO:0045945=PMID:12695546, GO:0035189=GO_REF:0000019, GO:0030099=PMID:15664994, GO:0030225=GO_REF:0000019, GO:0048469=GO_REF:0000019, GO:0008203=GO_REF:0000019, GO:0071285=GO_REF:0000019, GO:0048839=GO_REF:0000019, GO:0046982=GO_REF:0000019, GO:0001892=GO_REF:0000019, GO:0051384=GO_REF:0000019, GO:0006953=GO_REF:0000019, GO:0000122=GO_REF:0000019, GO:0003677=PMID:8643605, GO:0033274=GO_REF:0000019, GO:0006351=PMID:15664994, GO:0043565=GO_REF:0000002, GO:0045669=GO_REF:0000019, GO:0001889=GO_REF:0000019, GO:0071407=GO_REF:0000019, GO:0050872=GO_REF:0000019, GO:0050873=GO_REF:0000019, GO:0019048=GO_REF:0000037, GO:0000050=GO_REF:0000019, GO:0045600=GO_REF:0000019, GO:0071837=GO_REF:0000019, GO:0007005=GO_REF:0000019, GO:0008134=PMID:15664994} P49715 CCAAT/enhancer-binding protein alpha protein 20130415 {GO:0005515=IPI, GO:0003700=IDA, GO:0008285=IEA, GO:0006366=TAS, GO:0044212=IDA, GO:0030324=IEA, GO:0003705=NAS, GO:0019221=NAS, GO:0031100=IEA, GO:0005634=NAS, GO:0006091=TAS, GO:0032403=IEA, GO:0016363=IEA, GO:0042803=IEA, GO:0045944=IEA, GO:0045945=IDA, GO:0035189=IEA, GO:0030099=NAS, GO:0030225=IEA, GO:0048469=IEA, GO:0008203=IEA, GO:0071285=IEA, GO:0048839=IEA, GO:0046982=IEA, GO:0001892=IEA, GO:0051384=IEA, GO:0006953=IEA, GO:0000122=IEA, GO:0003677=TAS, GO:0033274=IEA, GO:0006351=IDA, GO:0043565=IEA, GO:0045669=IEA, GO:0001889=IEA, GO:0071407=IEA, GO:0050872=IEA, GO:0050873=IEA, GO:0019048=IEA, GO:0000050=IEA, GO:0045600=IEA, GO:0071837=IEA, GO:0007005=IEA, GO:0008134=IPI} acute-phase response, brown fat cell differentiation, cell maturation, cellular response to lithium ion, cellular response to organic cyclic compound, cholesterol metabolic process, cytokine-mediated signaling pathway, embryonic placenta development, generation of precursor metabolites and energy, inner ear development, liver development, lung development, macrophage differentiation, mitochondrion organization, myeloid cell differentiation, negative regulation of cell proliferation, negative regulation of transcription from RNA polymerase II promoter, organ regeneration, positive regulation of fat cell differentiation, positive regulation of osteoblast differentiation, positive regulation of transcription from RNA polymerase II promoter, positive regulation of transcription from RNA polymerase III promoter, response to glucocorticoid stimulus, response to vitamin B2, transcription from RNA polymerase II promoter, transcription, DNA-dependent, urea cycle, virus-host interaction, white fat cell differentiation Rb-E2F complex, nuclear matrix, nucleus DNA binding, HMG box domain binding, RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity, protein binding, protein complex binding, protein heterodimerization activity, protein homodimerization activity, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, transcription factor binding, transcription regulatory region DNA binding Human UniProtKB:P09874 CEBPB BHF-UCL UniProtKB {GO:0005515=PMID:17724128, GO:0034976=PMID:20829347, GO:0000790=GO_REF:0000019, GO:0003700=PMID:10821850, GO:0006366=PMID:10821850, GO:0003705=GO_REF:0000024, GO:0005634=PMID:20829347, GO:0045408=GO_REF:0000019, GO:0035259=GO_REF:0000019, GO:0042803=GO_REF:0000019, GO:0016363=GO_REF:0000019, GO:0006955=PMID:2112087, GO:0005737=GO_REF:0000019, GO:0006954=PMID:2112087, GO:0060644=GO_REF:0000019, GO:0071230=GO_REF:0000019, GO:0030182=GO_REF:0000019, GO:0032496=GO_REF:0000019, GO:0006355=PMID:20829347, GO:0043066=GO_REF:0000019, GO:0046982=GO_REF:0000019, GO:0001892=GO_REF:0000019, GO:0006917=GO_REF:0000019, GO:0006953=PMID:2112087, GO:0003677=PMID:10821850, GO:0043565=GO_REF:0000019, GO:0045669=GO_REF:0000019, GO:0033598=GO_REF:0000019, GO:0001077=GO_REF:0000019, GO:0050873=GO_REF:0000019, GO:0045892=GO_REF:0000019, GO:0008134=GO_REF:0000019} P17676 CCAAT/enhancer-binding protein beta protein 20080331 {GO:0005515=IPI, GO:0034976=IDA, GO:0000790=IEA, GO:0003700=NAS, GO:0006366=TAS, GO:0003705=ISS, GO:0005634=IDA, GO:0045408=IEA, GO:0035259=IEA, GO:0042803=IEA, GO:0016363=IEA, GO:0006955=TAS, GO:0005737=IEA, GO:0006954=TAS, GO:0060644=IEA, GO:0071230=IEA, GO:0030182=IEA, GO:0032496=IEA, GO:0006355=IDA, GO:0043066=IEA, GO:0046982=IEA, GO:0001892=IEA, GO:0006917=IEA, GO:0006953=TAS, GO:0003677=TAS, GO:0043565=IEA, GO:0045669=IEA, GO:0033598=IEA, GO:0001077=IEA, GO:0050873=IEA, GO:0045892=IEA, GO:0008134=IEA} acute-phase response, brown fat cell differentiation, cellular response to amino acid stimulus, embryonic placenta development, immune response, induction of apoptosis, inflammatory response, mammary gland epithelial cell differentiation, mammary gland epithelial cell proliferation, negative regulation of apoptotic process, negative regulation of transcription, DNA-dependent, neuron differentiation, positive regulation of osteoblast differentiation, regulation of interleukin-6 biosynthetic process, regulation of transcription, DNA-dependent, response to endoplasmic reticulum stress, response to lipopolysaccharide, transcription from RNA polymerase II promoter cytoplasm, nuclear chromatin, nuclear matrix, nucleus DNA binding, RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription, RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity, glucocorticoid receptor binding, protein binding, protein heterodimerization activity, protein homodimerization activity, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, transcription factor binding Human UniProtKB:Q96RU8 CEBPD PINC UniProtKB {GO:0043565=GO_REF:0000019, GO:0003700=GO_REF:0000002, GO:0006366=PMID:8314590, GO:0005634=GO_REF:0000039} P49716 CCAAT/enhancer-binding protein delta protein 20030904 {GO:0043565=IEA, GO:0003700=IEA, GO:0006366=TAS, GO:0005634=IEA} transcription from RNA polymerase II promoter nucleus sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity Human CEBPE HPA UniProtKB {GO:0006909=GO_REF:0000019, GO:0003700=GO_REF:0000002, GO:0046982=GO_REF:0000019, GO:0005730=GO_REF:0000052, GO:0006952=PMID:8661101, GO:0005634=GO_REF:0000052, GO:0042089=GO_REF:0000019, GO:0006351=GO_REF:0000037, GO:0042803=GO_REF:0000019, GO:0043565=GO_REF:0000002, GO:0071222=GO_REF:0000019, GO:0030225=GO_REF:0000019, GO:0042742=GO_REF:0000019} Q15744 CCAAT/enhancer-binding protein epsilon protein 20100326 {GO:0006909=IEA, GO:0003700=IEA, GO:0046982=IEA, GO:0005730=IDA, GO:0006952=TAS, GO:0005634=IDA, GO:0042089=IEA, GO:0006351=IEA, GO:0042803=IEA, GO:0043565=IEA, GO:0071222=IEA, GO:0030225=IEA, GO:0042742=IEA} cellular response to lipopolysaccharide, cytokine biosynthetic process, defense response, defense response to bacterium, macrophage differentiation, phagocytosis, transcription, DNA-dependent nucleolus, nucleus protein heterodimerization activity, protein homodimerization activity, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity NOT Human CEBPG HPA UniProtKB {GO:0005515=PMID:7665092, GO:0003700=GO_REF:0000002, GO:0006357=PMID:16255782, GO:0046982=PMID:7665092, GO:0016071=GO_REF:0000019, GO:0042267=GO_REF:0000024, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0045739=PMID:16255782, GO:0043353=GO_REF:0000024, GO:0003677=PMID:7665092, GO:0043433=PMID:7501458, GO:0006351=GO_REF:0000037, GO:0001889=GO_REF:0000024, GO:0043565=PMID:7665092, GO:0006955=GO_REF:0000024, GO:0051091=PMID:7665092, GO:0003690=GO_REF:0000019, GO:0045078=GO_REF:0000024, GO:0030183=GO_REF:0000024, GO:0043388=PMID:7665092, GO:0008134=PMID:7665092} P53567 CCAAT/enhancer-binding protein gamma protein 20081203 {GO:0005515=IPI, GO:0003700=IEA, GO:0006357=IDA, GO:0046982=IDA, GO:0016071=IEA, GO:0042267=ISS, GO:0005730=IDA, GO:0005634=IDA, GO:0045739=IEP, GO:0043353=ISS, GO:0003677=IDA, GO:0043433=ISS, GO:0006351=IEA, GO:0001889=ISS, GO:0043565=IDA, GO:0006955=ISS, GO:0051091=TAS, GO:0003690=IEA, GO:0045078=ISS, GO:0030183=ISS, GO:0043388=TAS, GO:0008134=IDA} B cell differentiation, enucleate erythrocyte differentiation, immune response, liver development, mRNA metabolic process, natural killer cell mediated cytotoxicity, negative regulation of sequence-specific DNA binding transcription factor activity, positive regulation of DNA binding, positive regulation of DNA repair, positive regulation of interferon-gamma biosynthetic process, positive regulation of sequence-specific DNA binding transcription factor activity, regulation of transcription from RNA polymerase II promoter, transcription, DNA-dependent nucleolus, nucleus DNA binding, double-stranded DNA binding, protein binding, protein heterodimerization activity, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, transcription factor binding NOT Human CEBPZ PINC UniProtKB {GO:0006355=GO_REF:0000037, GO:0006366=PMID:2247079, GO:0005634=GO_REF:0000039, GO:0003677=PMID:2247079} Q03701 CCAAT/enhancer-binding protein zeta protein 20030904 {GO:0006355=IEA, GO:0006366=TAS, GO:0005634=IEA, GO:0003677=TAS} regulation of transcription, DNA-dependent, transcription from RNA polymerase II promoter nucleus DNA binding Human CECR1 HPA UniProtKB {GO:0009168=GO_REF:0000002, GO:0005794=GO_REF:0000052, GO:0019239=GO_REF:0000002, GO:0046103=GO_REF:0000033, GO:0043394=PMID:20147294, GO:0007275=PMID:10756095, GO:0005615=PMID:20147294, GO:0031685=PMID:20147294, GO:0042803=PMID:20147294, GO:0005829=GO_REF:0000033, GO:0004000=PMID:20147294, GO:0006154=PMID:20147294, GO:0043103=GO_REF:0000033, GO:0008270=PMID:20147294, GO:0008201=GO_REF:0000037, GO:0008083=PMID:10756095} Q9NZK5 Adenosine deaminase CECR1 protein 20101115 {GO:0009168=IEA, GO:0005794=IDA, GO:0019239=IEA, GO:0046103=IBA, GO:0043394=IDA, GO:0007275=NAS, GO:0005615=IDA, GO:0031685=IDA, GO:0042803=IPI, GO:0005829=IRD, GO:0004000=IDA, GO:0006154=IDA, GO:0043103=IBA, GO:0008270=IDA, GO:0008201=IEA, GO:0008083=NAS} adenosine catabolic process, hypoxanthine salvage, inosine biosynthetic process, multicellular organismal development, purine ribonucleoside monophosphate biosynthetic process Golgi apparatus, cytosol, extracellular space adenosine deaminase activity, adenosine receptor binding, deaminase activity, growth factor activity, heparin binding, protein homodimerization activity, proteoglycan binding, zinc ion binding Human CECR2 HGNC UniProtKB {GO:0000910=PMID:11827465, GO:0006309=PMID:12762840, GO:0005719=GO_REF:0000019, GO:0043044=PMID:15640247, GO:0007010=PMID:11827465, GO:0021915=GO_REF:0000019, GO:0006915=PMID:12762840, GO:0005634=PMID:12762840, GO:0090537=PMID:15640247, GO:0016192=PMID:11827465} Q9BXF3 Cat eye syndrome critical region protein 2 protein 20060721 {GO:0000910=NAS, GO:0006309=TAS, GO:0005719=IEA, GO:0043044=IDA, GO:0007010=NAS, GO:0021915=IEA, GO:0006915=IDA, GO:0005634=IDA, GO:0090537=IDA, GO:0016192=NAS} ATP-dependent chromatin remodeling, apoptotic DNA fragmentation, apoptotic process, cytokinesis, cytoskeleton organization, neural tube development, vesicle-mediated transport CERF complex, nuclear euchromatin, nucleus Human CECR5 ENSEMBL UniProtKB {GO:0005739=GO_REF:0000019, GO:0016787=GO_REF:0000002} Q9BXW7 Cat eye syndrome critical region protein 5 protein 20130413 {GO:0005739=IEA, GO:0016787=IEA} mitochondrion hydrolase activity Human Ensembl:ENSMUSP00000074775 CECR6 null null {} null null null null {} null null null CEL Reactome UniProtKB {GO:0006629=Reactome:REACT_602, GO:0004091=GO_REF:0000033, GO:0006707=PMID:12031288, GO:0004806=PMID:2265692, GO:0044241=Reactome:REACT_9518, GO:0005576=Reactome:REACT_9502, GO:0044281=Reactome:REACT_111217, GO:0050253=GO_REF:0000003, GO:0030157=PMID:1854805, GO:0003824=PMID:2265692, GO:0005615=GO_REF:0000033, GO:0018350=PMID:7578248, GO:0005829=GO_REF:0000033, GO:0009062=PMID:7578248, GO:0030299=PMID:12031288, GO:0005737=GO_REF:0000024, GO:0016787=PMID:2265692, GO:0047372=Reactome:REACT_9502, GO:0006641=PMID:2265692, GO:0046514=GO_REF:0000019, GO:0044258=PMID:7578248, GO:0008201=PMID:7578248, GO:0004771=Reactome:REACT_9468} P19835 Bile salt-activated lipase protein 20070202 {GO:0006629=TAS, GO:0004091=IBA, GO:0006707=IDA, GO:0004806=NAS, GO:0044241=TAS, GO:0005576=TAS, GO:0044281=TAS, GO:0050253=IEA, GO:0030157=IDA, GO:0003824=TAS, GO:0005615=IBA, GO:0018350=NAS, GO:0005829=IBA, GO:0009062=NAS, GO:0030299=NAS, GO:0005737=ISS, GO:0016787=TAS, GO:0047372=TAS, GO:0006641=IC, GO:0046514=IEA, GO:0044258=NAS, GO:0008201=NAS, GO:0004771=TAS} ceramide catabolic process, cholesterol catabolic process, fatty acid catabolic process, intestinal cholesterol absorption, intestinal lipid catabolic process, lipid digestion, lipid metabolic process, pancreatic juice secretion, protein esterification, small molecule metabolic process, triglyceride metabolic process cytoplasm, cytosol, extracellular region, extracellular space acylglycerol lipase activity, carboxylesterase activity, catalytic activity, heparin binding, hydrolase activity, retinyl-palmitate esterase activity, sterol esterase activity, triglyceride lipase activity Human CELA1 UniProtKB UniProtKB {GO:0004252=GO_REF:0000002, GO:0005576=GO_REF:0000039, GO:0000122=GO_REF:0000019, GO:0061113=GO_REF:0000019, GO:0009791=GO_REF:0000019, GO:0046872=GO_REF:0000037, GO:0006954=GO_REF:0000019, GO:0035264=GO_REF:0000019, GO:0042127=GO_REF:0000019, GO:0045944=GO_REF:0000019, GO:0031017=GO_REF:0000019, GO:0006508=GO_REF:0000037, GO:0045595=GO_REF:0000019, GO:0016055=GO_REF:0000019} Q9UNI1 Chymotrypsin-like elastase family member 1 protein 20130413 {GO:0004252=IEA, GO:0005576=IEA, GO:0000122=IEA, GO:0061113=IEA, GO:0009791=IEA, GO:0046872=IEA, GO:0006954=IEA, GO:0035264=IEA, GO:0042127=IEA, GO:0045944=IEA, GO:0031017=IEA, GO:0006508=IEA, GO:0045595=IEA, GO:0016055=IEA} Wnt receptor signaling pathway, exocrine pancreas development, inflammatory response, multicellular organism growth, negative regulation of transcription from RNA polymerase II promoter, pancreas morphogenesis, positive regulation of transcription from RNA polymerase II promoter, post-embryonic development, proteolysis, regulation of cell differentiation, regulation of cell proliferation extracellular region metal ion binding, serine-type endopeptidase activity Human UniProtKB-SubCell:SL-0243 CELF1 BHF-UCL UniProtKB {GO:0006397=PMID:8948631, GO:0005515=PMID:16946708, GO:0016246=PMID:10893231, GO:0042835=PMID:10893231, GO:0003723=PMID:16946708, GO:0006376=GO_REF:0000024, GO:0007286=GO_REF:0000019, GO:0005634=PMID:10893231, GO:0009790=PMID:10893231, GO:0003729=PMID:14726956, GO:0003676=GO_REF:0000002, GO:0007281=PMID:10893231, GO:0005737=GO_REF:0000039, GO:0000166=GO_REF:0000002, GO:0030529=PMID:10893231, GO:0043484=PMID:16946708, GO:0031369=GO_REF:0000019, GO:0040018=GO_REF:0000019, GO:0000900=PMID:10893231} Q92879 CUGBP Elav-like family member 1 protein 20081001 {GO:0006397=TAS, GO:0005515=IPI, GO:0016246=NAS, GO:0042835=IDA, GO:0003723=IDA, GO:0006376=ISS, GO:0007286=IEA, GO:0005634=NAS, GO:0009790=NAS, GO:0003729=IDA, GO:0003676=IEA, GO:0007281=NAS, GO:0005737=IEA, GO:0000166=IEA, GO:0030529=NAS, GO:0043484=IDA, GO:0031369=IEA, GO:0040018=IEA, GO:0000900=NAS} RNA interference, embryo development, germ cell development, mRNA processing, mRNA splice site selection, positive regulation of multicellular organism growth, regulation of RNA splicing, spermatid development cytoplasm, nucleus, ribonucleoprotein complex BRE binding, RNA binding, mRNA binding, nucleic acid binding, nucleotide binding, protein binding, translation initiation factor binding, translation repressor activity, nucleic acid binding Human CELF2 InterPro UniProtKB {GO:0006397=GO_REF:0000037, GO:0006396=PMID:9887331, GO:0005737=GO_REF:0000039, GO:0000166=GO_REF:0000002, GO:0003723=GO_REF:0000002, GO:0008016=PMID:9887331, GO:0006376=GO_REF:0000019, GO:0005634=GO_REF:0000039} Q5VZZ6 CUGBP Elav-like family member 2 protein 20130413 {GO:0006397=IEA, GO:0006396=TAS, GO:0005737=IEA, GO:0000166=IEA, GO:0003723=IEA, GO:0008016=TAS, GO:0006376=IEA, GO:0005634=IEA} RNA processing, mRNA processing, mRNA splice site selection, regulation of heart contraction cytoplasm, nucleus RNA binding, nucleotide binding Human InterPro:IPR002343 CELF3 UniProtKB UniProtKB {GO:0048026=PMID:15009664, GO:0008380=PMID:17725984, GO:0005737=PMID:17725984, GO:0000166=GO_REF:0000002, GO:0000381=PMID:11158314, GO:0000398=PMID:11158314, GO:0003723=PMID:17725984, GO:0005634=PMID:17725984, GO:0030317=GO_REF:0000019, GO:0007283=GO_REF:0000019, GO:0003729=PMID:11158314, GO:0003676=GO_REF:0000002} Q5SZQ8 CUGBP Elav-like family member 3 protein 20110725 {GO:0048026=IDA, GO:0008380=IMP, GO:0005737=IDA, GO:0000166=IEA, GO:0000381=IDA, GO:0000398=NAS, GO:0003723=IMP, GO:0005634=IDA, GO:0030317=IEA, GO:0007283=IEA, GO:0003729=NAS, GO:0003676=IEA} RNA splicing, mRNA splicing, via spliceosome, positive regulation of mRNA splicing, via spliceosome, regulation of alternative mRNA splicing, via spliceosome, sperm motility, spermatogenesis cytoplasm, nucleus RNA binding, mRNA binding, nucleic acid binding, nucleotide binding Human CELF4 HPA UniProtKB {GO:0048026=PMID:15009664, GO:0042835=GO_REF:0000024, GO:0006376=GO_REF:0000019, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0009790=PMID:10893231, GO:0003676=GO_REF:0000002, GO:0003729=GO_REF:0000019, GO:0007281=PMID:10893231, GO:0005737=GO_REF:0000039, GO:0090394=GO_REF:0000019, GO:0000166=GO_REF:0000002, GO:0000381=PMID:19720736, GO:0000380=PMID:19720736, GO:0000900=PMID:10893231} Q9BZC1 CUGBP Elav-like family member 4 protein 20110516 {GO:0048026=IDA, GO:0042835=ISS, GO:0006376=IEA, GO:0005730=IDA, GO:0005634=IDA, GO:0009790=NAS, GO:0003676=IEA, GO:0003729=IEA, GO:0007281=NAS, GO:0005737=IEA, GO:0090394=IEA, GO:0000166=IEA, GO:0000381=IDA, GO:0000380=IDA, GO:0000900=NAS} alternative mRNA splicing, via spliceosome, embryo development, germ cell development, mRNA splice site selection, negative regulation of excitatory postsynaptic membrane potential, positive regulation of mRNA splicing, via spliceosome, regulation of alternative mRNA splicing, via spliceosome cytoplasm, nucleolus, nucleus BRE binding, mRNA binding, nucleic acid binding, nucleotide binding, translation repressor activity, nucleic acid binding NOT Human CELF5 UniProtKB UniProtKB {GO:0006397=GO_REF:0000037, GO:0005737=GO_REF:0000039, GO:0000166=GO_REF:0000002, GO:0003723=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0003676=GO_REF:0000002} Q8N6W0 CUGBP Elav-like family member 5 protein 20130413 {GO:0006397=IEA, GO:0005737=IEA, GO:0000166=IEA, GO:0003723=IEA, GO:0005634=IEA, GO:0003676=IEA} mRNA processing cytoplasm, nucleus RNA binding, nucleic acid binding, nucleotide binding Human UniProtKB-SubCell:SL-0086 CELSR1 UniProtKB UniProtKB {GO:0001736=GO_REF:0000024, GO:0005886=GO_REF:0000002, GO:0007266=GO_REF:0000019, GO:0009952=GO_REF:0000019, GO:0042249=GO_REF:0000019, GO:0007218=GO_REF:0000002, GO:0032956=GO_REF:0000019, GO:0046983=PMID:9339365, GO:0007626=GO_REF:0000019, GO:0001942=GO_REF:0000019, GO:0007156=GO_REF:0000002, GO:0060490=GO_REF:0000019, GO:0042472=GO_REF:0000019, GO:0004930=PMID:9339365, GO:0090251=GO_REF:0000019, GO:0005509=GO_REF:0000002, GO:0090179=GO_REF:0000019, GO:0001843=GO_REF:0000024, GO:0045176=GO_REF:0000019, GO:0007417=PMID:10716726, GO:0007186=PMID:9339365, GO:0005887=PMID:9339365, GO:0060489=GO_REF:0000019, GO:0042060=GO_REF:0000019, GO:0060488=GO_REF:0000019, GO:0016021=PMID:10716726, GO:0001764=GO_REF:0000019, GO:0048105=GO_REF:0000019, GO:0004888=PMID:9339365} Q9NYQ6 Cadherin EGF LAG seven-pass G-type receptor 1 protein 20060515 {GO:0001736=ISS, GO:0005886=IEA, GO:0007266=IEA, GO:0009952=IEA, GO:0042249=IEA, GO:0007218=IEA, GO:0032956=IEA, GO:0046983=NAS, GO:0007626=IEA, GO:0001942=IEA, GO:0007156=IEA, GO:0060490=IEA, GO:0042472=IEA, GO:0004930=NAS, GO:0090251=IEA, GO:0005509=IEA, GO:0090179=IEA, GO:0001843=ISS, GO:0045176=IEA, GO:0007417=TAS, GO:0007186=NAS, GO:0005887=TAS, GO:0060489=IEA, GO:0042060=IEA, GO:0060488=IEA, GO:0016021=TAS, GO:0001764=IEA, GO:0048105=IEA, GO:0004888=NAS} G-protein coupled receptor signaling pathway, Rho protein signal transduction, anterior/posterior pattern specification, apical protein localization, central nervous system development, establishment of body hair planar orientation, establishment of planar polarity, establishment of planar polarity of embryonic epithelium, hair follicle development, homophilic cell adhesion, inner ear morphogenesis, lateral sprouting involved in lung morphogenesis, locomotory behavior, neural tube closure, neuron migration, neuropeptide signaling pathway, orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis, planar cell polarity pathway involved in neural tube closure, planar dichotomous subdivision of terminal units involved in lung branching morphogenesis, protein localization involved in establishment of planar polarity, regulation of actin cytoskeleton organization, wound healing integral to membrane, integral to plasma membrane, plasma membrane G-protein coupled receptor activity, calcium ion binding, protein dimerization activity, transmembrane signaling receptor activity Human CELSR2 BHF-UCL UniProtKB {GO:0022407=GO_REF:0000024, GO:0006355=GO_REF:0000024, GO:0005886=GO_REF:0000024, GO:0004930=PMID:10907856, GO:0005509=GO_REF:0000002, GO:0021999=GO_REF:0000024, GO:0048813=GO_REF:0000024, GO:0005737=GO_REF:0000024, GO:0007186=PMID:10907856, GO:0007218=GO_REF:0000002, GO:0021591=GO_REF:0000019, GO:0016021=PMID:10907856, GO:0016055=GO_REF:0000024, GO:0001764=GO_REF:0000019, GO:0007156=GO_REF:0000024} Q9HCU4 Cadherin EGF LAG seven-pass G-type receptor 2 protein 20071123 {GO:0022407=ISS, GO:0006355=ISS, GO:0005886=ISS, GO:0004930=NAS, GO:0005509=IEA, GO:0021999=ISS, GO:0048813=ISS, GO:0005737=ISS, GO:0007186=NAS, GO:0007218=IEA, GO:0021591=IEA, GO:0016021=NAS, GO:0016055=ISS, GO:0001764=IEA, GO:0007156=ISS} G-protein coupled receptor signaling pathway, Wnt receptor signaling pathway, dendrite morphogenesis, homophilic cell adhesion, neural plate anterior/posterior regionalization, neuron migration, neuropeptide signaling pathway, regulation of cell-cell adhesion, regulation of transcription, DNA-dependent, ventricular system development cytoplasm, integral to membrane, plasma membrane G-protein coupled receptor activity, calcium ion binding Human UniProtKB:Q9QYP2 CELSR3 IntAct UniProtKB {GO:0005515=PMID:17474147, GO:0007413=GO_REF:0000019, GO:0007186=PMID:15203201, GO:0005886=GO_REF:0000039, GO:0004930=GO_REF:0000037, GO:0007218=GO_REF:0000002, GO:0005509=GO_REF:0000002, GO:0016021=GO_REF:0000037, GO:0001764=GO_REF:0000019, GO:0007156=GO_REF:0000002} Q9NYQ7 Cadherin EGF LAG seven-pass G-type receptor 3 protein 20130415 {GO:0005515=IPI, GO:0007413=IEA, GO:0007186=TAS, GO:0005886=IEA, GO:0004930=IEA, GO:0007218=IEA, GO:0005509=IEA, GO:0016021=IEA, GO:0001764=IEA, GO:0007156=IEA} G-protein coupled receptor signaling pathway, axonal fasciculation, homophilic cell adhesion, neuron migration, neuropeptide signaling pathway integral to membrane, plasma membrane G-protein coupled receptor activity, calcium ion binding, protein binding Human UniProtKB:P16333 CEMP1 UniProtKB UniProtKB {GO:0005737=GO_REF:0000039} Q6PRD7 Cementoblastoma-derived protein 1 protein 20130413 {GO:0005737=IEA} cytoplasm Human UniProtKB-SubCell:SL-0086 CEND1 UniProtKB UniProtKB {GO:0016021=GO_REF:0000037} Q8N111 Cell cycle exit and neuronal differentiation protein 1 protein 20130413 {GO:0016021=IEA} integral to membrane Human UniProtKB-KW:KW-0812 CENPA BHF-UCL UniProtKB {GO:0005515=PMID:21478274, GO:0000780=PMID:11682612, GO:0000236=Reactome:REACT_682, GO:0046982=GO_REF:0000002, GO:0006334=Reactome:REACT_22344, GO:0000132=PMID:19468067, GO:0005634=PMID:7962047, GO:0071459=PMID:11682612, GO:0003677=GO_REF:0000037, GO:0005829=Reactome:REACT_150414, GO:0034080=Reactome:REACT_22186, GO:0051382=PMID:11682612, GO:0019048=GO_REF:0000037, GO:0003682=PMID:7962047, GO:0000087=Reactome:REACT_910, GO:0005654=Reactome:REACT_22217, GO:0000778=PMID:18195732, GO:0000278=Reactome:REACT_152, GO:0000786=GO_REF:0000037, GO:0000090=Reactome:REACT_1275, GO:0000939=GO_REF:0000019, GO:0000775=PMID:11084331} P49450 Histone H3-like centromeric protein A protein 20100106 {GO:0005515=IPI, GO:0000780=IDA, GO:0000236=TAS, GO:0046982=IEA, GO:0006334=TAS, GO:0000132=IMP, GO:0005634=TAS, GO:0071459=IDA, GO:0003677=IEA, GO:0005829=TAS, GO:0034080=TAS, GO:0051382=IDA, GO:0019048=IEA, GO:0003682=TAS, GO:0000087=TAS, GO:0005654=TAS, GO:0000778=IDA, GO:0000278=TAS, GO:0000786=IEA, GO:0000090=TAS, GO:0000939=IEA, GO:0000775=IDA} CENP-A containing nucleosome assembly at centromere, M phase of mitotic cell cycle, establishment of mitotic spindle orientation, kinetochore assembly, mitotic anaphase, mitotic cell cycle, mitotic prometaphase, nucleosome assembly, protein localization to chromosome, centromeric region, virus-host interaction chromosome, centromeric region, condensed chromosome inner kinetochore, condensed nuclear chromosome kinetochore, condensed nuclear chromosome, centromeric region, cytosol, nucleoplasm, nucleosome, nucleus DNA binding, chromatin binding, protein binding, protein heterodimerization activity Human CENPB BHF-UCL UniProtKB {GO:0043565=PMID:11682612, GO:0006355=GO_REF:0000002, GO:0003696=PMID:1893793, GO:0003682=PMID:1893793, GO:0019237=PMID:11682612, GO:0005634=GO_REF:0000039, GO:0000775=PMID:11682612} P07199 Major centromere autoantigen B protein 20091216 {GO:0043565=TAS, GO:0006355=IEA, GO:0003696=NAS, GO:0003682=NAS, GO:0019237=IC, GO:0005634=IEA, GO:0000775=IDA} regulation of transcription, DNA-dependent chromosome, centromeric region, nucleus centromeric DNA binding, chromatin binding, satellite DNA binding, sequence-specific DNA binding Human CENPBD1 UniProtKB UniProtKB {GO:0005634=GO_REF:0000039, GO:0003677=GO_REF:0000037} B2RD01 CENPB DNA-binding domain-containing protein 1 protein 20130413 {GO:0005634=IEA, GO:0003677=IEA} nucleus DNA binding Human UniProtKB-SubCell:SL-0191 CENPC1 HPA UniProtKB {GO:0000780=PMID:11682612, GO:0000236=Reactome:REACT_682, GO:0005634=GO_REF:0000052, GO:0003677=GO_REF:0000037, GO:0005829=Reactome:REACT_150414, GO:0005737=GO_REF:0000052, GO:0051382=PMID:21529714, GO:0005721=PMID:21529714, GO:0007059=PMID:21529714, GO:0000087=Reactome:REACT_910, GO:0000777=GO_REF:0000039, GO:0000776=PMID:21529714, GO:0000278=Reactome:REACT_152, GO:0000090=Reactome:REACT_1275, GO:0051301=GO_REF:0000037} Q03188 Centromere protein C 1 protein 20120912 {GO:0000780=IDA, GO:0000236=TAS, GO:0005634=IDA, GO:0003677=IEA, GO:0005829=TAS, GO:0005737=IDA, GO:0051382=IMP, GO:0005721=IDA, GO:0007059=IMP, GO:0000087=TAS, GO:0000777=IEA, GO:0000776=IDA, GO:0000278=TAS, GO:0000090=TAS, GO:0051301=IEA} M phase of mitotic cell cycle, cell division, chromosome segregation, kinetochore assembly, mitotic anaphase, mitotic cell cycle, mitotic prometaphase centromeric heterochromatin, condensed chromosome kinetochore, condensed nuclear chromosome, centromeric region, cytoplasm, cytosol, kinetochore, nucleus DNA binding Human CENPE HPA UniProtKB {GO:0005515=PMID:9763420, GO:0000236=Reactome:REACT_682, GO:0005634=PMID:9763420, GO:0007079=PMID:1406971, GO:0005829=Reactome:REACT_150414, GO:0019886=Reactome:REACT_121399, GO:0005737=GO_REF:0000052, GO:0051382=PMID:9763420, GO:0000089=PMID:2022189, GO:0015630=GO_REF:0000052, GO:0045860=PMID:12925705, GO:0000087=Reactome:REACT_910, GO:0007018=Reactome:REACT_25201, GO:0005875=GO_REF:0000002, GO:0005874=PMID:7889940, GO:0005819=GO_REF:0000039, GO:0007275=GO_REF:0000037, GO:0003777=PMID:7889940, GO:0005524=GO_REF:0000037, GO:0000940=PMID:9763420, GO:0007596=Reactome:REACT_604, GO:0000776=PMID:11682612, GO:0000779=PMID:19465021, GO:0043515=PMID:9763420, GO:0000778=GO_REF:0000019, GO:0007080=PMID:9363944, GO:0000278=Reactome:REACT_152, GO:0000090=Reactome:REACT_1275, GO:0000775=PMID:11084331, GO:0051301=GO_REF:0000037} Q02224 Centromere-associated protein E protein 20110516 {GO:0005515=IPI, GO:0000236=TAS, GO:0005634=IMP, GO:0007079=TAS, GO:0005829=TAS, GO:0019886=TAS, GO:0005737=IDA, GO:0051382=NAS, GO:0000089=TAS, GO:0015630=IDA, GO:0045860=IMP, GO:0000087=TAS, GO:0007018=TAS, GO:0005875=IEA, GO:0005874=IDA, GO:0005819=IEA, GO:0007275=IEA, GO:0003777=IMP, GO:0005524=IEA, GO:0000940=TAS, GO:0007596=TAS, GO:0000776=IDA, GO:0000779=IDA, GO:0043515=IDA, GO:0000778=IEA, GO:0007080=TAS, GO:0000278=TAS, GO:0000090=TAS, GO:0000775=IDA, GO:0051301=IEA} M phase of mitotic cell cycle, antigen processing and presentation of exogenous peptide antigen via MHC class II, blood coagulation, cell division, kinetochore assembly, microtubule-based movement, mitotic anaphase, mitotic cell cycle, mitotic chromosome movement towards spindle pole, mitotic metaphase, mitotic metaphase plate congression, mitotic prometaphase, multicellular organismal development, positive regulation of protein kinase activity chromosome, centromeric region, condensed chromosome outer kinetochore, condensed chromosome, centromeric region, condensed nuclear chromosome kinetochore, cytoplasm, cytosol, kinetochore, microtubule, microtubule associated complex, microtubule cytoskeleton, nucleus, spindle ATP binding, kinetochore binding, microtubule motor activity, protein binding Human CENPF Reactome UniProtKB {GO:0005515=PMID:17363900, GO:0000236=Reactome:REACT_682, GO:0007094=PMID:12974617, GO:0048471=GO_REF:0000039, GO:0008283=PMID:12507285, GO:0005634=PMID:15494374, GO:0005635=PMID:12154071, GO:0015031=PMID:17600710, GO:0016363=PMID:7542657, GO:0042803=PMID:7642639, GO:0030154=GO_REF:0000037, GO:0005829=Reactome:REACT_150414, GO:0000085=PMID:12154071, GO:0005737=PMID:12974617, GO:0051382=PMID:16252009, GO:0007059=PMID:16252009, GO:0000087=Reactome:REACT_910, GO:0016202=PMID:10373470, GO:0000785=PMID:9891037, GO:0051310=PMID:15870278, GO:0010389=PMID:7651420, GO:0042493=PMID:12467231, GO:0005819=PMID:7651420, GO:0030496=PMID:7651420, GO:0008022=PMID:7642639, GO:0006260=GO_REF:0000037, GO:0000922=PMID:7542657, GO:0000940=PMID:7642639, GO:0045502=PMID:12974617, GO:0007517=GO_REF:0000037, GO:0003682=PMID:9891037, GO:0000776=PMID:17363900, GO:0045120=GO_REF:0000019, GO:0000278=Reactome:REACT_152, GO:0000090=Reactome:REACT_1275, GO:0045892=PMID:15677469, GO:0000775=PMID:11084331, GO:0051301=GO_REF:0000037, GO:0008134=PMID:15677469} P49454 Centromere protein F protein 20130213 {GO:0005515=IPI, GO:0000236=TAS, GO:0007094=NAS, GO:0048471=IEA, GO:0008283=NAS, GO:0005634=IDA, GO:0005635=IDA, GO:0015031=IMP, GO:0016363=IDA, GO:0042803=IPI, GO:0030154=IEA, GO:0005829=TAS, GO:0000085=IMP, GO:0005737=IDA, GO:0051382=NAS, GO:0007059=IMP, GO:0000087=TAS, GO:0016202=ISS, GO:0000785=NAS, GO:0051310=IDA, GO:0010389=IMP, GO:0042493=NAS, GO:0005819=IDA, GO:0030496=IDA, GO:0008022=IPI, GO:0006260=IEA, GO:0000922=IDA, GO:0000940=IDA, GO:0045502=IDA, GO:0007517=IEA, GO:0003682=NAS, GO:0000776=IDA, GO:0045120=IEA, GO:0000278=TAS, GO:0000090=TAS, GO:0045892=IDA, GO:0000775=IDA, GO:0051301=IEA, GO:0008134=IPI} DNA replication, G2 phase of mitotic cell cycle, M phase of mitotic cell cycle, cell differentiation, cell division, cell proliferation, chromosome segregation, kinetochore assembly, metaphase plate congression, mitotic anaphase, mitotic cell cycle, mitotic prometaphase, mitotic spindle assembly checkpoint, muscle organ development, negative regulation of transcription, DNA-dependent, protein transport, regulation of G2/M transition of mitotic cell cycle, regulation of striated muscle tissue development, response to drug chromatin, chromosome, centromeric region, condensed chromosome outer kinetochore, cytoplasm, cytosol, kinetochore, midbody, nuclear envelope, nuclear matrix, nucleus, perinuclear region of cytoplasm, pronucleus, spindle, spindle pole chromatin binding, dynein binding, protein C-terminus binding, protein binding, protein homodimerization activity, transcription factor binding Human CENPH IntAct UniProtKB {GO:0005515=PMID:15713649, GO:0000236=Reactome:REACT_682, GO:0006334=Reactome:REACT_22344, GO:0005634=PMID:11092768, GO:0051383=PMID:11092768, GO:0005829=Reactome:REACT_150414, GO:0034080=Reactome:REACT_22186, GO:0007059=GO_REF:0000002, GO:0000087=Reactome:REACT_910, GO:0000777=GO_REF:0000039, GO:0000776=PMID:11092768, GO:0043515=PMID:11092768, GO:0005654=Reactome:REACT_22217, GO:0000278=Reactome:REACT_152, GO:0000090=Reactome:REACT_1275, GO:0051301=GO_REF:0000002} Q9H3R5 Centromere protein H protein 20130415 {GO:0005515=IPI, GO:0000236=TAS, GO:0006334=TAS, GO:0005634=IDA, GO:0051383=TAS, GO:0005829=TAS, GO:0034080=TAS, GO:0007059=IEA, GO:0000087=TAS, GO:0000777=IEA, GO:0000776=IDA, GO:0043515=IDA, GO:0005654=TAS, GO:0000278=TAS, GO:0000090=TAS, GO:0051301=IEA} CENP-A containing nucleosome assembly at centromere, M phase of mitotic cell cycle, cell division, chromosome segregation, kinetochore organization, mitotic anaphase, mitotic cell cycle, mitotic prometaphase, nucleosome assembly condensed chromosome kinetochore, cytosol, kinetochore, nucleoplasm, nucleus kinetochore binding, protein binding Human UniProtKB:O14777 CENPI Reactome UniProtKB {GO:0034080=Reactome:REACT_22186, GO:0005515=PMID:20212317, GO:0000236=Reactome:REACT_682, GO:0000087=Reactome:REACT_910, GO:0006334=Reactome:REACT_22344, GO:0000776=PMID:20212317, GO:0005654=Reactome:REACT_22217, GO:0007548=PMID:8921378, GO:0000278=Reactome:REACT_152, GO:0000090=Reactome:REACT_1275, GO:0005829=Reactome:REACT_150414} Q92674 Centromere protein I protein 20100417 {GO:0034080=TAS, GO:0005515=IPI, GO:0000236=TAS, GO:0000087=TAS, GO:0006334=TAS, GO:0000776=IDA, GO:0005654=TAS, GO:0007548=TAS, GO:0000278=TAS, GO:0000090=TAS, GO:0005829=TAS} CENP-A containing nucleosome assembly at centromere, M phase of mitotic cell cycle, mitotic anaphase, mitotic cell cycle, mitotic prometaphase, nucleosome assembly, sex differentiation cytosol, kinetochore, nucleoplasm protein binding Human CENPJ IntAct UniProtKB {GO:0005515=PMID:16713569, GO:0005813=PMID:21399614, GO:0007099=PMID:17681131, GO:0019901=PMID:20531387, GO:0005814=PMID:20531387, GO:0005874=GO_REF:0000037, GO:0019904=PMID:11984006, GO:0046599=PMID:20531387, GO:0005829=Reactome:REACT_15470, GO:0046785=PMID:15047868, GO:0015631=PMID:15047868, GO:0000086=Reactome:REACT_2203, GO:0007020=PMID:11003675, GO:0000278=Reactome:REACT_152, GO:0008275=PMID:11003675, GO:0051301=PMID:11003675} Q9HC77 Centromere protein J protein 20130415 {GO:0005515=IPI, GO:0005813=IDA, GO:0007099=IMP, GO:0019901=IPI, GO:0005814=IDA, GO:0005874=IEA, GO:0019904=IPI, GO:0046599=IMP, GO:0005829=TAS, GO:0046785=IMP, GO:0015631=IDA, GO:0000086=TAS, GO:0007020=TAS, GO:0000278=TAS, GO:0008275=NAS, GO:0051301=NAS} G2/M transition of mitotic cell cycle, cell division, centriole replication, microtubule nucleation, microtubule polymerization, mitotic cell cycle, regulation of centriole replication centriole, centrosome, cytosol, gamma-tubulin small complex, microtubule protein binding, protein domain specific binding, protein kinase binding, tubulin binding Human UniProtKB:Q96RK0 CENPK Reactome UniProtKB {GO:0034080=Reactome:REACT_22186, GO:0000236=Reactome:REACT_682, GO:0045944=GO_REF:0000019, GO:0000087=Reactome:REACT_910, GO:0006334=Reactome:REACT_22344, GO:0000777=GO_REF:0000039, GO:0005654=Reactome:REACT_22217, GO:0005634=GO_REF:0000002, GO:0000278=Reactome:REACT_152, GO:0000090=Reactome:REACT_1275, GO:0005829=Reactome:REACT_150414} Q9BS16 Centromere protein K protein 20100417 {GO:0034080=TAS, GO:0000236=TAS, GO:0045944=IEA, GO:0000087=TAS, GO:0006334=TAS, GO:0000777=IEA, GO:0005654=TAS, GO:0005634=IEA, GO:0000278=TAS, GO:0000090=TAS, GO:0005829=TAS} CENP-A containing nucleosome assembly at centromere, M phase of mitotic cell cycle, mitotic anaphase, mitotic cell cycle, mitotic prometaphase, nucleosome assembly, positive regulation of transcription from RNA polymerase II promoter condensed chromosome kinetochore, cytosol, nucleoplasm, nucleus Human CENPL Reactome UniProtKB {GO:0000236=Reactome:REACT_682, GO:0000087=Reactome:REACT_910, GO:0005634=GO_REF:0000039, GO:0000278=Reactome:REACT_152, GO:0000090=Reactome:REACT_1275, GO:0000775=GO_REF:0000039, GO:0005829=Reactome:REACT_150414} Q8N0S6 Centromere protein L protein 20120924 {GO:0000236=TAS, GO:0000087=TAS, GO:0005634=IEA, GO:0000278=TAS, GO:0000090=TAS, GO:0000775=IEA, GO:0005829=TAS} M phase of mitotic cell cycle, mitotic anaphase, mitotic cell cycle, mitotic prometaphase chromosome, centromeric region, cytosol, nucleus Human CENPM Reactome UniProtKB {GO:0000236=Reactome:REACT_682, GO:0000087=Reactome:REACT_910, GO:0000777=GO_REF:0000039, GO:0005634=GO_REF:0000039, GO:0000278=Reactome:REACT_152, GO:0000090=Reactome:REACT_1275, GO:0005829=Reactome:REACT_150414} Q9NSP4 Centromere protein M protein 20120924 {GO:0000236=TAS, GO:0000087=TAS, GO:0000777=IEA, GO:0005634=IEA, GO:0000278=TAS, GO:0000090=TAS, GO:0005829=TAS} M phase of mitotic cell cycle, mitotic anaphase, mitotic cell cycle, mitotic prometaphase condensed chromosome kinetochore, cytosol, nucleus Human CENPN Reactome UniProtKB {GO:0034080=Reactome:REACT_22186, GO:0000236=Reactome:REACT_682, GO:0000087=Reactome:REACT_910, GO:0006334=Reactome:REACT_22344, GO:0000777=GO_REF:0000039, GO:0005654=Reactome:REACT_22217, GO:0000278=Reactome:REACT_152, GO:0000090=Reactome:REACT_1275, GO:0005829=Reactome:REACT_150414} Q96H22 Centromere protein N protein 20100417 {GO:0034080=TAS, GO:0000236=TAS, GO:0000087=TAS, GO:0006334=TAS, GO:0000777=IEA, GO:0005654=TAS, GO:0000278=TAS, GO:0000090=TAS, GO:0005829=TAS} CENP-A containing nucleosome assembly at centromere, M phase of mitotic cell cycle, mitotic anaphase, mitotic cell cycle, mitotic prometaphase, nucleosome assembly condensed chromosome kinetochore, cytosol, nucleoplasm Human CENPO Reactome UniProtKB {GO:0034080=Reactome:REACT_22186, GO:0000236=Reactome:REACT_682, GO:0007059=GO_REF:0000002, GO:0000087=Reactome:REACT_910, GO:0006334=Reactome:REACT_22344, GO:0000777=GO_REF:0000039, GO:0005654=Reactome:REACT_22217, GO:0000278=Reactome:REACT_152, GO:0000090=Reactome:REACT_1275, GO:0005829=Reactome:REACT_150414, GO:0051301=GO_REF:0000002} Q9BU64 Centromere protein O protein 20100417 {GO:0034080=TAS, GO:0000236=TAS, GO:0007059=IEA, GO:0000087=TAS, GO:0006334=TAS, GO:0000777=IEA, GO:0005654=TAS, GO:0000278=TAS, GO:0000090=TAS, GO:0005829=TAS, GO:0051301=IEA} CENP-A containing nucleosome assembly at centromere, M phase of mitotic cell cycle, cell division, chromosome segregation, mitotic anaphase, mitotic cell cycle, mitotic prometaphase, nucleosome assembly condensed chromosome kinetochore, cytosol, nucleoplasm Human CENPP Reactome UniProtKB {GO:0034080=Reactome:REACT_22186, GO:0000236=Reactome:REACT_682, GO:0000087=Reactome:REACT_910, GO:0006334=Reactome:REACT_22344, GO:0005654=Reactome:REACT_22217, GO:0000278=Reactome:REACT_152, GO:0000090=Reactome:REACT_1275, GO:0000775=GO_REF:0000039, GO:0005829=Reactome:REACT_150414} Q6IPU0 Centromere protein P protein 20100417 {GO:0034080=TAS, GO:0000236=TAS, GO:0000087=TAS, GO:0006334=TAS, GO:0005654=TAS, GO:0000278=TAS, GO:0000090=TAS, GO:0000775=IEA, GO:0005829=TAS} CENP-A containing nucleosome assembly at centromere, M phase of mitotic cell cycle, mitotic anaphase, mitotic cell cycle, mitotic prometaphase, nucleosome assembly chromosome, centromeric region, cytosol, nucleoplasm Human CENPQ Reactome UniProtKB {GO:0034080=Reactome:REACT_22186, GO:0000236=Reactome:REACT_682, GO:0000087=Reactome:REACT_910, GO:0006334=Reactome:REACT_22344, GO:0005654=Reactome:REACT_22217, GO:0000278=Reactome:REACT_152, GO:0000090=Reactome:REACT_1275, GO:0000775=GO_REF:0000039, GO:0005829=Reactome:REACT_150414} Q7L2Z9 Centromere protein Q protein 20100417 {GO:0034080=TAS, GO:0000236=TAS, GO:0000087=TAS, GO:0006334=TAS, GO:0005654=TAS, GO:0000278=TAS, GO:0000090=TAS, GO:0000775=IEA, GO:0005829=TAS} CENP-A containing nucleosome assembly at centromere, M phase of mitotic cell cycle, mitotic anaphase, mitotic cell cycle, mitotic prometaphase, nucleosome assembly chromosome, centromeric region, cytosol, nucleoplasm Human CENPT Reactome UniProtKB {GO:0005515=PMID:19533040, GO:0000236=Reactome:REACT_682, GO:0051276=PMID:21695110, GO:0046982=GO_REF:0000002, GO:0005634=GO_REF:0000039, GO:0003677=GO_REF:0000037, GO:0005829=Reactome:REACT_150414, GO:0051382=PMID:21529714, GO:0007059=PMID:21529714, GO:0000087=Reactome:REACT_910, GO:0000777=GO_REF:0000039, GO:0000776=PMID:21529714, GO:0000278=Reactome:REACT_152, GO:0000090=Reactome:REACT_1275, GO:0000775=PMID:21695110, GO:0051301=GO_REF:0000037} Q96BT3 Centromere protein T protein 20130213 {GO:0005515=IPI, GO:0000236=TAS, GO:0051276=IMP, GO:0046982=IEA, GO:0005634=IEA, GO:0003677=IEA, GO:0005829=TAS, GO:0051382=IMP, GO:0007059=IMP, GO:0000087=TAS, GO:0000777=IEA, GO:0000776=IDA, GO:0000278=TAS, GO:0000090=TAS, GO:0000775=IDA, GO:0051301=IEA} M phase of mitotic cell cycle, cell division, chromosome organization, chromosome segregation, kinetochore assembly, mitotic anaphase, mitotic cell cycle, mitotic prometaphase chromosome, centromeric region, condensed chromosome kinetochore, cytosol, kinetochore, nucleus DNA binding, protein binding, protein heterodimerization activity Human CENPV HPA UniProtKB {GO:0016846=GO_REF:0000002, GO:0031508=PMID:18772885, GO:0032467=PMID:18772885, GO:0001667=PMID:19930468, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0051233=PMID:18772885, GO:0034508=PMID:18772885, GO:0003674=GO_REF:0000015, GO:0005737=GO_REF:0000052, GO:0007067=GO_REF:0000037, GO:0015630=PMID:19930468, GO:0000777=GO_REF:0000039, GO:0000776=PMID:18772885, GO:0051301=GO_REF:0000037, GO:0033044=PMID:18772885} Q7Z7K6 Centromere protein V protein 20111111 {GO:0016846=IEA, GO:0031508=IMP, GO:0032467=IMP, GO:0001667=IDA, GO:0005730=IDA, GO:0005634=IDA, GO:0051233=IDA, GO:0034508=IMP, GO:0003674=ND, GO:0005737=IDA, GO:0007067=IEA, GO:0015630=IDA, GO:0000777=IEA, GO:0000776=IDA, GO:0051301=IEA, GO:0033044=IMP} ameboidal cell migration, cell division, centromere complex assembly, centromeric heterochromatin assembly, mitosis, positive regulation of cytokinesis, regulation of chromosome organization condensed chromosome kinetochore, cytoplasm, kinetochore, microtubule cytoskeleton, nucleolus, nucleus, spindle midzone carbon-sulfur lyase activity, molecular_function Human CEP120 UniProtKB UniProtKB {GO:0032880=GO_REF:0000019, GO:0005737=GO_REF:0000037, GO:0005813=PMID:21399614, GO:0021987=GO_REF:0000019, GO:0022027=GO_REF:0000019, GO:0032886=GO_REF:0000019, GO:0030953=GO_REF:0000019, GO:0008022=GO_REF:0000019, GO:0022008=GO_REF:0000019} Q8N960 Centrosomal protein of 120 kDa protein 20110517 {GO:0032880=IEA, GO:0005737=IEA, GO:0005813=IDA, GO:0021987=IEA, GO:0022027=IEA, GO:0032886=IEA, GO:0030953=IEA, GO:0008022=IEA, GO:0022008=IEA} astral microtubule organization, cerebral cortex development, interkinetic nuclear migration, neurogenesis, regulation of microtubule-based process, regulation of protein localization centrosome, cytoplasm protein C-terminus binding Human CEP128 UniProtKB UniProtKB {GO:0000922=PMID:21399614, GO:0005814=PMID:21399614} Q6ZU80 Centrosomal protein of 128 kDa protein 20110518 {GO:0000922=IDA, GO:0005814=IDA} centriole, spindle pole Human CEP135 Reactome UniProtKB {GO:0005813=PMID:21399614, GO:0010457=PMID:18851962, GO:0007099=PMID:17681131, GO:0005814=PMID:17681131, GO:0000086=Reactome:REACT_2203, GO:0000278=Reactome:REACT_152, GO:0008022=PMID:18851962, GO:0005829=Reactome:REACT_15470} Q66GS9 Centrosomal protein of 135 kDa protein 20130213 {GO:0005813=IDA, GO:0010457=IMP, GO:0007099=IMP, GO:0005814=IDA, GO:0000086=TAS, GO:0000278=TAS, GO:0008022=IPI, GO:0005829=TAS} G2/M transition of mitotic cell cycle, centriole replication, centriole-centriole cohesion, mitotic cell cycle centriole, centrosome, cytosol protein C-terminus binding Human CEP152 HPA UniProtKB {GO:0005515=PMID:21131973, GO:0051298=PMID:20852615, GO:0005813=GO_REF:0000052, GO:0005737=GO_REF:0000052, GO:0019901=PMID:21059844, GO:0000086=Reactome:REACT_2203, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0000278=Reactome:REACT_152, GO:0005829=Reactome:REACT_15470} O94986 Centrosomal protein of 152 kDa protein 20110516 {GO:0005515=IPI, GO:0051298=IMP, GO:0005813=IDA, GO:0005737=IDA, GO:0019901=IPI, GO:0000086=TAS, GO:0005730=IDA, GO:0005634=IDA, GO:0000278=TAS, GO:0005829=TAS} G2/M transition of mitotic cell cycle, centrosome duplication, mitotic cell cycle centrosome, cytoplasm, cytosol, nucleolus, nucleus protein binding, protein kinase binding Human CEP164 HPA UniProtKB {GO:0005515=PMID:22863007, GO:0005813=GO_REF:0000052, GO:0005814=GO_REF:0000039, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0005829=Reactome:REACT_15470, GO:0042384=PMID:17954613, GO:0005737=GO_REF:0000052, GO:0007067=GO_REF:0000037, GO:0006281=GO_REF:0000037, GO:0000086=Reactome:REACT_2203, GO:0000278=Reactome:REACT_152, GO:0051301=GO_REF:0000037} Q9UPV0 Centrosomal protein of 164 kDa protein 20110516 {GO:0005515=IPI, GO:0005813=IDA, GO:0005814=IEA, GO:0005730=IDA, GO:0005634=IDA, GO:0005829=TAS, GO:0042384=IMP, GO:0005737=IDA, GO:0007067=IEA, GO:0006281=IEA, GO:0000086=TAS, GO:0000278=TAS, GO:0051301=IEA} DNA repair, G2/M transition of mitotic cell cycle, cell division, cilium assembly, mitosis, mitotic cell cycle centriole, centrosome, cytoplasm, cytosol, nucleolus, nucleus protein binding Human CEP170 IntAct UniProtKB {GO:0005515=PMID:22190034, GO:0005813=PMID:21399614, GO:0005814=GO_REF:0000039, GO:0005874=GO_REF:0000037, GO:0005819=GO_REF:0000039} Q5SW79 Centrosomal protein of 170 kDa protein 20130415 {GO:0005515=IPI, GO:0005813=IDA, GO:0005814=IEA, GO:0005874=IEA, GO:0005819=IEA} centriole, centrosome, microtubule, spindle protein binding Human UniProtKB:P12520 CEP19 UniProtKB UniProtKB {GO:0000922=PMID:21399614, GO:0005814=PMID:21399614} Q96LK0 Centrosomal protein of 19 kDa protein 20110518 {GO:0000922=IDA, GO:0005814=IDA} centriole, spindle pole Human CEP192 HPA UniProtKB {GO:0005515=PMID:19389623, GO:0051298=PMID:17980596, GO:0005813=GO_REF:0000052, GO:0005737=GO_REF:0000052, GO:0019902=PMID:19389623, GO:0005814=GO_REF:0000039, GO:0000086=Reactome:REACT_2203, GO:0010923=PMID:19389623, GO:0000278=Reactome:REACT_152, GO:0051225=PMID:17980596, GO:0000242=GO_REF:0000019, GO:0005829=Reactome:REACT_15470} Q8TEP8 Centrosomal protein of 192 kDa protein 20110516 {GO:0005515=IPI, GO:0051298=IMP, GO:0005813=IDA, GO:0005737=IDA, GO:0019902=IDA, GO:0005814=IEA, GO:0000086=TAS, GO:0010923=IDA, GO:0000278=TAS, GO:0051225=IMP, GO:0000242=IEA, GO:0005829=TAS} G2/M transition of mitotic cell cycle, centrosome duplication, mitotic cell cycle, negative regulation of phosphatase activity, spindle assembly centriole, centrosome, cytoplasm, cytosol, pericentriolar material phosphatase binding, protein binding Human CEP250 Reactome UniProtKB {GO:0005515=PMID:10880350, GO:0010457=PMID:18851962, GO:0048471=GO_REF:0000039, GO:0005813=PMID:21399614, GO:0005815=PMID:9647649, GO:0019901=PMID:9647649, GO:0005814=PMID:18851962, GO:0008022=PMID:18851962, GO:0005829=Reactome:REACT_15470, GO:0005929=GO_REF:0000037, GO:0043234=PMID:10880350, GO:0030997=PMID:9647649, GO:0008104=PMID:18851962, GO:0000086=Reactome:REACT_2203, GO:0031616=GO_REF:0000019, GO:0005932=GO_REF:0000039, GO:0000278=Reactome:REACT_152} Q9BV73 Centrosome-associated protein CEP250 protein 20130213 {GO:0005515=IPI, GO:0010457=IMP, GO:0048471=IEA, GO:0005813=IDA, GO:0005815=NAS, GO:0019901=IPI, GO:0005814=IDA, GO:0008022=IPI, GO:0005829=TAS, GO:0005929=IEA, GO:0043234=IMP, GO:0030997=IDA, GO:0008104=IMP, GO:0000086=TAS, GO:0031616=IEA, GO:0005932=IEA, GO:0000278=TAS} G2/M transition of mitotic cell cycle, centriole-centriole cohesion, mitotic cell cycle, protein localization, regulation of centriole-centriole cohesion centriole, centrosome, cilium, cytosol, microtubule basal body, microtubule organizing center, perinuclear region of cytoplasm, protein complex, spindle pole centrosome protein C-terminus binding, protein binding, protein kinase binding Human CEP290 IntAct UniProtKB {GO:0005515=PMID:22863007, GO:0005813=PMID:16682973, GO:0060041=GO_REF:0000019, GO:0009986=PMID:12493773, GO:0048793=PMID:16682973, GO:0030916=PMID:16682973, GO:0036038=GO_REF:0000024, GO:0005634=PMID:16682973, GO:0015031=GO_REF:0000024, GO:0005829=Reactome:REACT_15470, GO:0042384=GO_REF:0000024, GO:0005737=PMID:14654843, GO:0000086=Reactome:REACT_2203, GO:0000930=PMID:16682973, GO:0060271=GO_REF:0000024, GO:0051011=PMID:16682973, GO:0032391=PMID:16682973, GO:0005932=GO_REF:0000039, GO:0000278=Reactome:REACT_152, GO:0045893=PMID:16682973, GO:0042462=PMID:16682973, GO:0030902=PMID:16682973} O15078 Centrosomal protein of 290 kDa protein 20130415 {GO:0005515=IPI, GO:0005813=IDA, GO:0060041=IEA, GO:0009986=IDA, GO:0048793=ISS, GO:0030916=ISS, GO:0036038=ISS, GO:0005634=IDA, GO:0015031=ISS, GO:0005829=TAS, GO:0042384=ISS, GO:0005737=IDA, GO:0000086=TAS, GO:0000930=IDA, GO:0060271=ISS, GO:0051011=IDA, GO:0032391=ISS, GO:0005932=IEA, GO:0000278=TAS, GO:0045893=IDA, GO:0042462=ISS, GO:0030902=ISS} G2/M transition of mitotic cell cycle, cilium assembly, cilium morphogenesis, eye photoreceptor cell development, hindbrain development, mitotic cell cycle, otic vesicle formation, positive regulation of transcription, DNA-dependent, pronephros development, protein transport, retina development in camera-type eye TCTN-B9D complex, cell surface, centrosome, cytoplasm, cytosol, gamma-tubulin complex, microtubule basal body, nucleus, photoreceptor connecting cilium microtubule minus-end binding, protein binding Human UniProtKB:Q2M1K9 CEP350 HPA UniProtKB {GO:0005813=GO_REF:0000052, GO:0005737=GO_REF:0000052, GO:0005819=GO_REF:0000039, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052} Q5VT06 Centrosome-associated protein 350 protein 20101115 {GO:0005813=IDA, GO:0005737=IDA, GO:0005819=IEA, GO:0005730=IDA, GO:0005634=IDA} centrosome, cytoplasm, nucleolus, nucleus, spindle Human CEP44 UniProtKB UniProtKB {GO:0005813=PMID:21399614, GO:0000922=PMID:21399614, GO:0005737=GO_REF:0000037, GO:0030496=PMID:21399614} Q9C0F1 Centrosomal protein of 44 kDa protein 20110518 {GO:0005813=IDA, GO:0000922=IDA, GO:0005737=IEA, GO:0030496=TAS} centrosome, cytoplasm, midbody, spindle pole Human CEP55 MGI UniProtKB {GO:0000910=PMID:19638580, GO:0005813=PMID:20186884, GO:0007067=GO_REF:0000037, GO:0005814=GO_REF:0000039, GO:0030496=PMID:20186884, GO:0032154=GO_REF:0000039, GO:0045171=GO_REF:0000019} Q53EZ4 Centrosomal protein of 55 kDa protein 20120203 {GO:0000910=IGI, GO:0005813=IDA, GO:0007067=IEA, GO:0005814=IEA, GO:0030496=IDA, GO:0032154=IEA, GO:0045171=IEA} cytokinesis, mitosis centriole, centrosome, cleavage furrow, intercellular bridge, midbody Human CEP57 HPA UniProtKB {GO:0005515=PMID:20195357, GO:0008017=GO_REF:0000002, GO:0005813=PMID:21399614, GO:0005794=PMID:10942595, GO:0034453=GO_REF:0000002, GO:0043015=GO_REF:0000002, GO:0017134=PMID:12717444, GO:0005874=PMID:12717444, GO:0007286=PMID:12954732, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0042803=PMID:12717444, GO:0005829=Reactome:REACT_15470, GO:0042802=GO_REF:0000002, GO:0005737=GO_REF:0000052, GO:0008543=PMID:12717444, GO:0000086=Reactome:REACT_2203, GO:0015630=GO_REF:0000052, GO:0051260=GO_REF:0000019, GO:0000278=Reactome:REACT_152, GO:0000060=PMID:12717444} Q86XR8 Centrosomal protein of 57 kDa protein 20090616 {GO:0005515=IPI, GO:0008017=IEA, GO:0005813=IDA, GO:0005794=IDA, GO:0034453=IEA, GO:0043015=IEA, GO:0017134=IPI, GO:0005874=IDA, GO:0007286=ISS, GO:0005730=IDA, GO:0005634=IDA, GO:0042803=IPI, GO:0005829=TAS, GO:0042802=IEA, GO:0005737=IDA, GO:0008543=IPI, GO:0000086=TAS, GO:0015630=IDA, GO:0051260=IEA, GO:0000278=TAS, GO:0000060=ISS} G2/M transition of mitotic cell cycle, fibroblast growth factor receptor signaling pathway, microtubule anchoring, mitotic cell cycle, protein homooligomerization, protein import into nucleus, translocation, spermatid development Golgi apparatus, centrosome, cytoplasm, cytosol, microtubule, microtubule cytoskeleton, nucleolus, nucleus fibroblast growth factor binding, gamma-tubulin binding, identical protein binding, microtubule binding, protein binding, protein homodimerization activity Human CEP57L1 UniProtKB UniProtKB {GO:0008017=GO_REF:0000002, GO:0008150=GO_REF:0000015, GO:0003674=GO_REF:0000015, GO:0005737=GO_REF:0000037, GO:0005815=GO_REF:0000039, GO:0043015=GO_REF:0000002, GO:0034453=GO_REF:0000002, GO:0005874=GO_REF:0000037, GO:0005575=GO_REF:0000015, GO:0042802=GO_REF:0000002} Q8IYX8 Centrosomal protein CEP57L1 protein 20061026 {GO:0008017=IEA, GO:0008150=ND, GO:0003674=ND, GO:0005737=IEA, GO:0005815=IEA, GO:0043015=IEA, GO:0034453=IEA, GO:0005874=IEA, GO:0005575=ND, GO:0042802=IEA} biological_process, microtubule anchoring cellular_component, cytoplasm, microtubule, microtubule organizing center gamma-tubulin binding, identical protein binding, microtubule binding, molecular_function Human CEP63 IntAct UniProtKB {GO:0005515=PMID:17043677, GO:0042770=GO_REF:0000024, GO:0000922=GO_REF:0000024, GO:0005813=PMID:21399614, GO:0007067=GO_REF:0000037, GO:0000086=Reactome:REACT_2203, GO:0000077=GO_REF:0000024, GO:0000278=Reactome:REACT_152, GO:0051225=GO_REF:0000024, GO:0005829=Reactome:REACT_15470, GO:0051301=GO_REF:0000037} Q96MT8 Centrosomal protein of 63 kDa protein 20130415 {GO:0005515=IPI, GO:0042770=ISS, GO:0000922=ISS, GO:0005813=IDA, GO:0007067=IEA, GO:0000086=TAS, GO:0000077=ISS, GO:0000278=TAS, GO:0051225=ISS, GO:0005829=TAS, GO:0051301=IEA} DNA damage checkpoint, G2/M transition of mitotic cell cycle, cell division, mitosis, mitotic cell cycle, signal transduction in response to DNA damage, spindle assembly centrosome, cytosol, spindle pole protein binding Human UniProtKB:Q9NRI5 CEP68 UniProtKB UniProtKB {GO:0051297=PMID:18042621, GO:0005813=PMID:21399614, GO:0005737=GO_REF:0000037} Q76N32 Centrosomal protein of 68 kDa protein 20110517 {GO:0051297=IMP, GO:0005813=IDA, GO:0005737=IEA} centrosome organization centrosome, cytoplasm Human CEP70 HPA UniProtKB {GO:0005515=PMID:19060904, GO:0005813=PMID:21399614, GO:0031965=GO_REF:0000052, GO:0005737=GO_REF:0000052, GO:0000086=Reactome:REACT_2203, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0000278=Reactome:REACT_152, GO:0005829=Reactome:REACT_15470} Q8NHQ1 Centrosomal protein of 70 kDa protein 20110516 {GO:0005515=IPI, GO:0005813=IDA, GO:0031965=IDA, GO:0005737=IDA, GO:0000086=TAS, GO:0005730=IDA, GO:0005634=IDA, GO:0000278=TAS, GO:0005829=TAS} G2/M transition of mitotic cell cycle, mitotic cell cycle centrosome, cytoplasm, cytosol, nuclear membrane, nucleolus, nucleus protein binding Human CEP72 IntAct UniProtKB {GO:0005515=PMID:21078624, GO:0005813=PMID:21399614, GO:0000086=Reactome:REACT_2203, GO:0007051=PMID:19536135, GO:0000278=Reactome:REACT_152, GO:0033566=PMID:19536135, GO:0005829=Reactome:REACT_15470, GO:0042802=GO_REF:0000019} Q9P209 Centrosomal protein of 72 kDa protein 20130415 {GO:0005515=IPI, GO:0005813=IDA, GO:0000086=TAS, GO:0007051=IMP, GO:0000278=TAS, GO:0033566=IMP, GO:0005829=TAS, GO:0042802=IEA} G2/M transition of mitotic cell cycle, gamma-tubulin complex localization, mitotic cell cycle, spindle organization centrosome, cytosol identical protein binding, protein binding Human UniProtKB:O15265 CEP76 Reactome UniProtKB {GO:0005515=PMID:19460342, GO:0005813=PMID:21399614, GO:0005814=PMID:19460342, GO:0000086=Reactome:REACT_2203, GO:0000278=Reactome:REACT_152, GO:0046599=PMID:19460342, GO:0005829=Reactome:REACT_15470} Q8TAP6 Centrosomal protein of 76 kDa protein 20130213 {GO:0005515=IPI, GO:0005813=IDA, GO:0005814=IDA, GO:0000086=TAS, GO:0000278=TAS, GO:0046599=IMP, GO:0005829=TAS} G2/M transition of mitotic cell cycle, mitotic cell cycle, regulation of centriole replication centriole, centrosome, cytosol protein binding Human CEP78 Reactome UniProtKB {GO:0005813=PMID:21399614, GO:0000086=Reactome:REACT_2203, GO:0000278=Reactome:REACT_152, GO:0005829=Reactome:REACT_15470} Q5JTW2 Centrosomal protein of 78 kDa protein 20130213 {GO:0005813=IDA, GO:0000086=TAS, GO:0000278=TAS, GO:0005829=TAS} G2/M transition of mitotic cell cycle, mitotic cell cycle centrosome, cytosol Human CEP85 UniProtKB UniProtKB {GO:0000922=PMID:21399614, GO:0005813=PMID:21399614, GO:0005737=GO_REF:0000037, GO:0005730=PMID:21399614} Q6P2H3 Centrosomal protein of 85 kDa protein 20110518 {GO:0000922=IDA, GO:0005813=IDA, GO:0005737=IEA, GO:0005730=IDA} centrosome, cytoplasm, nucleolus, spindle pole Human CEP85L UniProtKB UniProtKB {GO:0005813=PMID:21399614, GO:0005737=GO_REF:0000037} Q5SZL2 Centrosomal protein of 85 kDa-like protein 20110518 {GO:0005813=TAS, GO:0005737=IEA} centrosome, cytoplasm Human CEP89 HPA UniProtKB {GO:0005737=GO_REF:0000052, GO:0000922=PMID:21399614, GO:0005813=PMID:21399614, GO:0005886=GO_REF:0000052} Q96ST8 Centrosomal protein of 89 kDa protein 20110516 {GO:0005737=IDA, GO:0000922=IDA, GO:0005813=IDA, GO:0005886=IDA} centrosome, cytoplasm, plasma membrane, spindle pole Human CEP95 UniProtKB UniProtKB {GO:0005737=GO_REF:0000037, GO:0005813=PMID:21399614, GO:0000922=PMID:21399614} Q96GE4 Centrosomal protein of 95 kDa protein 20110518 {GO:0005737=IEA, GO:0005813=IDA, GO:0000922=IDA} centrosome, cytoplasm, spindle pole Human CEP97 HPA UniProtKB {GO:0005515=PMID:21620453, GO:0005516=GO_REF:0000037, GO:0005813=GO_REF:0000052, GO:0005737=GO_REF:0000052, GO:0030030=GO_REF:0000037, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052} Q8IW35 Centrosomal protein of 97 kDa protein 20101115 {GO:0005515=IPI, GO:0005516=IEA, GO:0005813=IDA, GO:0005737=IDA, GO:0030030=IEA, GO:0005730=IDA, GO:0005634=IDA} cell projection organization centrosome, cytoplasm, nucleolus, nucleus calmodulin binding, protein binding Human CEPT1 GOC UniProtKB {GO:0006629=PMID:10191259, GO:0006646=Reactome:REACT_120919, GO:0031965=GO_REF:0000039, GO:0004307=GO_REF:0000003, GO:0044281=Reactome:REACT_111217, GO:0046872=GO_REF:0000037, GO:0005789=Reactome:REACT_121214, GO:0016021=GO_REF:0000037, GO:0004142=Reactome:REACT_120896, GO:0006644=Reactome:REACT_120870, GO:0006657=Reactome:REACT_120896, GO:0006656=Reactome:REACT_121238, GO:0046474=Reactome:REACT_121401} Q9Y6K0 Choline/ethanolaminephosphotransferase 1 protein 20130413 {GO:0006629=TAS, GO:0006646=TAS, GO:0031965=IEA, GO:0004307=IEA, GO:0044281=TAS, GO:0046872=IEA, GO:0005789=TAS, GO:0016021=IEA, GO:0004142=TAS, GO:0006644=TAS, GO:0006657=TAS, GO:0006656=TAS, GO:0046474=TAS} CDP-choline pathway, glycerophospholipid biosynthetic process, lipid metabolic process, phosphatidylcholine biosynthetic process, phosphatidylethanolamine biosynthetic process, phospholipid metabolic process, small molecule metabolic process endoplasmic reticulum membrane, integral to membrane, nuclear membrane diacylglycerol cholinephosphotransferase activity, ethanolaminephosphotransferase activity, metal ion binding Human CER1 BHF-UCL UniProtKB {GO:0071773=PMID:16798745, GO:0003419=PMID:19113921, GO:0001657=GO_REF:0000024, GO:0007369=PMID:10049596, GO:0008285=PMID:10049596, GO:0035582=PMID:9660951, GO:2000381=GO_REF:0000024, GO:0023019=PMID:10049596, GO:0030178=GO_REF:0000024, GO:0032926=GO_REF:0000024, GO:0005576=PMID:10049596, GO:0030509=Reactome:REACT_12034, GO:0030282=PMID:19113921, GO:0009952=PMID:10049596, GO:0005615=GO_REF:0000024, GO:0005125=GO_REF:0000037, GO:0042803=GO_REF:0000024, GO:0007399=PMID:9660951, GO:0030514=PMID:10049596, GO:0016015=PMID:9660951, GO:0042074=PMID:10049596, GO:0009948=PMID:10049596, GO:0036122=PMID:9660951, GO:0048263=PMID:9660951} O95813 Cerberus protein 20120221 {GO:0071773=ISS, GO:0003419=ISS, GO:0001657=ISS, GO:0007369=ISS, GO:0008285=ISS, GO:0035582=IDA, GO:2000381=ISS, GO:0023019=ISS, GO:0030178=ISS, GO:0032926=ISS, GO:0005576=ISS, GO:0030509=TAS, GO:0030282=IMP, GO:0009952=ISS, GO:0005615=ISS, GO:0005125=IEA, GO:0042803=ISS, GO:0007399=IMP, GO:0030514=ISS, GO:0016015=IDA, GO:0042074=ISS, GO:0009948=ISS, GO:0036122=IDA, GO:0048263=IMP} BMP signaling pathway, anterior/posterior axis specification, anterior/posterior pattern specification, bone mineralization, cell migration involved in gastrulation, cellular response to BMP stimulus, determination of dorsal identity, gastrulation, growth plate cartilage chondrocyte proliferation, negative regulation of BMP signaling pathway, negative regulation of Wnt receptor signaling pathway, negative regulation of activin receptor signaling pathway, negative regulation of cell proliferation, negative regulation of mesoderm development, nervous system development, sequestering of BMP in extracellular matrix, signal transduction involved in regulation of gene expression, ureteric bud development extracellular region, extracellular space BMP binding, cytokine activity, morphogen activity, protein homodimerization activity Human CERCAM PINC UniProtKB {GO:0005886=PMID:10608765, GO:0007159=PMID:10608765, GO:0006928=PMID:10608765, GO:0005788=GO_REF:0000039, GO:0007155=PMID:10608765, GO:0009103=GO_REF:0000002} Q5T4B2 Probable inactive glycosyltransferase 25 family member 3 protein 20030904 {GO:0005886=NAS, GO:0007159=TAS, GO:0006928=TAS, GO:0005788=IEA, GO:0007155=IDA, GO:0009103=IEA} cell adhesion, cellular component movement, leukocyte cell-cell adhesion, lipopolysaccharide biosynthetic process endoplasmic reticulum lumen, plasma membrane Human CERK HPA UniProtKB {GO:0006665=Reactome:REACT_19323, GO:0000287=PMID:10947957, GO:0006687=Reactome:REACT_116105, GO:0005886=Reactome:REACT_116045, GO:0006672=PMID:19501188, GO:0005634=GO_REF:0000052, GO:0044281=Reactome:REACT_111217, GO:0005524=GO_REF:0000037, GO:0007205=GO_REF:0000002, GO:0001729=PMID:19501188, GO:0005739=GO_REF:0000019, GO:0005737=GO_REF:0000052, GO:0005543=GO_REF:0000002, GO:0004143=GO_REF:0000002, GO:0016021=PMID:11956206} Q8TCT0 Ceramide kinase protein 20090616 {GO:0006665=TAS, GO:0000287=IDA, GO:0006687=TAS, GO:0005886=TAS, GO:0006672=IDA, GO:0005634=IDA, GO:0044281=TAS, GO:0005524=IEA, GO:0007205=IEA, GO:0001729=IDA, GO:0005739=IEA, GO:0005737=IDA, GO:0005543=IEA, GO:0004143=IEA, GO:0016021=IDA} ceramide metabolic process, glycosphingolipid metabolic process, protein kinase C-activating G-protein coupled receptor signaling pathway, small molecule metabolic process, sphingolipid metabolic process cytoplasm, integral to membrane, mitochondrion, nucleus, plasma membrane ATP binding, ceramide kinase activity, diacylglycerol kinase activity, magnesium ion binding, phospholipid binding Human CERS1 BHF-UCL UniProtKB {GO:0006665=Reactome:REACT_19323, GO:0003674=GO_REF:0000015, GO:0000139=GO_REF:0000039, GO:0030148=Reactome:REACT_115810, GO:0005789=Reactome:REACT_19234, GO:0044281=Reactome:REACT_111217, GO:0050291=GO_REF:0000024, GO:0016021=GO_REF:0000037, GO:0046513=GO_REF:0000024, GO:0043231=GO_REF:0000024} P27544 Ceramide synthase 1 protein 20120828 {GO:0006665=TAS, GO:0003674=ND, GO:0000139=IEA, GO:0030148=TAS, GO:0005789=TAS, GO:0044281=TAS, GO:0050291=ISS, GO:0016021=IEA, GO:0046513=ISS, GO:0043231=ISS} ceramide biosynthetic process, small molecule metabolic process, sphingolipid biosynthetic process, sphingolipid metabolic process Golgi membrane, endoplasmic reticulum membrane, integral to membrane, intracellular membrane-bounded organelle molecular_function, sphingosine N-acyltransferase activity Human UniProtKB:P27545 CERS2 HPA UniProtKB {GO:0005515=PMID:21988832, GO:0006665=Reactome:REACT_19323, GO:0031965=GO_REF:0000052, GO:0003700=GO_REF:0000002, GO:0005783=GO_REF:0000052, GO:0030148=Reactome:REACT_115810, GO:0044281=Reactome:REACT_111217, GO:0003677=GO_REF:0000002, GO:0043565=GO_REF:0000002, GO:0005789=Reactome:REACT_19234, GO:0016021=GO_REF:0000037, GO:0050291=GO_REF:0000019, GO:0046513=GO_REF:0000019} Q96G23 Ceramide synthase 2 protein 20101115 {GO:0005515=IPI, GO:0006665=TAS, GO:0031965=IDA, GO:0003700=IEA, GO:0005783=IDA, GO:0030148=TAS, GO:0044281=TAS, GO:0003677=IEA, GO:0043565=IEA, GO:0005789=TAS, GO:0016021=IEA, GO:0050291=IEA, GO:0046513=IEA} ceramide biosynthetic process, small molecule metabolic process, sphingolipid biosynthetic process, sphingolipid metabolic process endoplasmic reticulum, endoplasmic reticulum membrane, integral to membrane, nuclear membrane DNA binding, protein binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, sphingosine N-acyltransferase activity Human CERS3 Reactome UniProtKB {GO:0006665=Reactome:REACT_19323, GO:0043565=GO_REF:0000002, GO:0031965=GO_REF:0000039, GO:0003700=GO_REF:0000002, GO:0030148=Reactome:REACT_115810, GO:0005789=Reactome:REACT_19234, GO:0005634=GO_REF:0000040, GO:0044281=Reactome:REACT_111217, GO:0016021=GO_REF:0000037, GO:0050291=GO_REF:0000019} Q8IU89 Ceramide synthase 3 protein 20130301 {GO:0006665=TAS, GO:0043565=IEA, GO:0031965=IEA, GO:0003700=IEA, GO:0030148=TAS, GO:0005789=TAS, GO:0005634=IEA, GO:0044281=TAS, GO:0016021=IEA, GO:0050291=IEA} small molecule metabolic process, sphingolipid biosynthetic process, sphingolipid metabolic process endoplasmic reticulum membrane, integral to membrane, nuclear membrane, nucleus sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, sphingosine N-acyltransferase activity Human CERS5 Reactome UniProtKB {GO:0006665=Reactome:REACT_19323, GO:0043565=GO_REF:0000002, GO:0031965=GO_REF:0000039, GO:0003700=GO_REF:0000002, GO:0005783=GO_REF:0000019, GO:0030148=Reactome:REACT_115810, GO:0005789=Reactome:REACT_19234, GO:0005634=GO_REF:0000040, GO:0044281=Reactome:REACT_111217, GO:0050291=PMID:16951403, GO:0016021=GO_REF:0000037, GO:0046513=PMID:16951403} Q8N5B7 Ceramide synthase 5 protein 20130301 {GO:0006665=TAS, GO:0043565=IEA, GO:0031965=IEA, GO:0003700=IEA, GO:0005783=IEA, GO:0030148=TAS, GO:0005789=TAS, GO:0005634=IEA, GO:0044281=TAS, GO:0050291=IDA, GO:0016021=IEA, GO:0046513=IDA} ceramide biosynthetic process, small molecule metabolic process, sphingolipid biosynthetic process, sphingolipid metabolic process endoplasmic reticulum, endoplasmic reticulum membrane, integral to membrane, nuclear membrane, nucleus sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, sphingosine N-acyltransferase activity Human CERS6 Reactome UniProtKB {GO:0006665=Reactome:REACT_19323, GO:0043565=GO_REF:0000002, GO:0031965=GO_REF:0000039, GO:0003700=GO_REF:0000002, GO:0030148=Reactome:REACT_115810, GO:0005789=Reactome:REACT_19234, GO:0044281=Reactome:REACT_111217, GO:0050291=GO_REF:0000019, GO:0016021=GO_REF:0000037, GO:0046513=GO_REF:0000019} Q6ZMG9 Ceramide synthase 6 protein 20130301 {GO:0006665=TAS, GO:0043565=IEA, GO:0031965=IEA, GO:0003700=IEA, GO:0030148=TAS, GO:0005789=TAS, GO:0044281=TAS, GO:0050291=IEA, GO:0016021=IEA, GO:0046513=IEA} ceramide biosynthetic process, small molecule metabolic process, sphingolipid biosynthetic process, sphingolipid metabolic process endoplasmic reticulum membrane, integral to membrane, nuclear membrane sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, sphingosine N-acyltransferase activity Human CES1 PINC UniProtKB {GO:0004091=GO_REF:0000033, GO:0016787=GO_REF:0000038, GO:0008152=PMID:1918003, GO:0009636=PMID:1918003, GO:0005788=GO_REF:0000039, GO:0047374=GO_REF:0000003, GO:0080030=GO_REF:0000003, GO:0050253=GO_REF:0000003, GO:0080031=GO_REF:0000003, GO:0080032=GO_REF:0000003} P23141 Liver carboxylesterase 1 protein 20030904 {GO:0004091=IBA, GO:0016787=IEA, GO:0008152=TAS, GO:0009636=TAS, GO:0005788=IEA, GO:0047374=IEA, GO:0080030=IEA, GO:0050253=IEA, GO:0080031=IEA, GO:0080032=IEA} metabolic process, response to toxic substance endoplasmic reticulum lumen carboxylesterase activity, hydrolase activity, methyl indole-3-acetate esterase activity, methyl jasmonate esterase activity, methyl salicylate esterase activity, methylumbelliferyl-acetate deacetylase activity, retinyl-palmitate esterase activity Human CES3 RefGenome UniProtKB {GO:0004091=GO_REF:0000033, GO:0016787=GO_REF:0000038, GO:0005788=GO_REF:0000039, GO:0080030=GO_REF:0000003, GO:0050253=GO_REF:0000003, GO:0080031=GO_REF:0000003, GO:0080032=GO_REF:0000003} Q6UWW8 Carboxylesterase 3 protein 20110225 {GO:0004091=IBA, GO:0016787=IEA, GO:0005788=IEA, GO:0080030=IEA, GO:0050253=IEA, GO:0080031=IEA, GO:0080032=IEA} endoplasmic reticulum lumen carboxylesterase activity, hydrolase activity, methyl indole-3-acetate esterase activity, methyl jasmonate esterase activity, methyl salicylate esterase activity, retinyl-palmitate esterase activity Human PANTHER:PTN000168392 CETN1 UniProtKB UniProtKB {GO:0005515=PMID:20643351, GO:0008026=GO_REF:0000002, GO:0008017=GO_REF:0000019, GO:0005813=PMID:8175926, GO:0005509=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0031683=GO_REF:0000019, GO:0005524=GO_REF:0000002, GO:0034605=GO_REF:0000019, GO:0005737=GO_REF:0000037, GO:0007067=GO_REF:0000037, GO:0000922=PMID:8175926, GO:0032795=GO_REF:0000019, GO:0032391=GO_REF:0000019, GO:0051301=GO_REF:0000037} Q12798 Centrin-1 protein 20120708 {GO:0005515=IPI, GO:0008026=IEA, GO:0008017=IEA, GO:0005813=IDA, GO:0005509=IEA, GO:0003676=IEA, GO:0031683=IEA, GO:0005524=IEA, GO:0034605=IEA, GO:0005737=IEA, GO:0007067=IEA, GO:0000922=IDA, GO:0032795=IEA, GO:0032391=IEA, GO:0051301=IEA} cell division, cellular response to heat, mitosis centrosome, cytoplasm, photoreceptor connecting cilium, spindle pole ATP binding, ATP-dependent helicase activity, G-protein beta/gamma-subunit complex binding, calcium ion binding, heterotrimeric G-protein binding, microtubule binding, nucleic acid binding, protein binding Human UniProtKB:Q9D9W1 CETN2 IntAct UniProtKB {GO:0005515=PMID:21962512, GO:0008026=GO_REF:0000002, GO:0008017=GO_REF:0000019, GO:0005813=PMID:21399614, GO:0032465=PMID:16760425, GO:0007099=PMID:12176356, GO:0005814=PMID:12176356, GO:0005509=PMID:8248209, GO:0071942=PMID:11279143, GO:0007283=GO_REF:0000019, GO:0003676=GO_REF:0000002, GO:0031683=GO_REF:0000019, GO:0005524=GO_REF:0000002, GO:0005829=Reactome:REACT_15470, GO:0005622=GO_REF:0000054, GO:0007067=PMID:8248209, GO:0032795=GO_REF:0000019, GO:0000086=Reactome:REACT_2203, GO:0032391=GO_REF:0000019, GO:0006289=PMID:15964821, GO:0005932=GO_REF:0000019, GO:0000278=Reactome:REACT_152, GO:0051301=GO_REF:0000037} P41208 Centrin-2 protein 20130415 {GO:0005515=IPI, GO:0008026=IEA, GO:0008017=IEA, GO:0005813=IDA, GO:0032465=IMP, GO:0007099=IMP, GO:0005814=IDA, GO:0005509=NAS, GO:0071942=IDA, GO:0007283=IEA, GO:0003676=IEA, GO:0031683=IEA, GO:0005524=IEA, GO:0005829=TAS, GO:0005622=IDA, GO:0007067=NAS, GO:0032795=IEA, GO:0000086=TAS, GO:0032391=IEA, GO:0006289=IDA, GO:0005932=IEA, GO:0000278=TAS, GO:0051301=IEA} G2/M transition of mitotic cell cycle, cell division, centriole replication, mitosis, mitotic cell cycle, nucleotide-excision repair, regulation of cytokinesis, spermatogenesis XPC complex, centriole, centrosome, cytosol, intracellular, microtubule basal body, photoreceptor connecting cilium ATP binding, ATP-dependent helicase activity, G-protein beta/gamma-subunit complex binding, calcium ion binding, heterotrimeric G-protein binding, microtubule binding, nucleic acid binding, protein binding Human UniProtKB:Q01831 CETN3 HPA UniProtKB {GO:0008017=GO_REF:0000019, GO:0005813=PMID:21399614, GO:0007067=GO_REF:0000037, GO:0005737=GO_REF:0000052, GO:0007098=PMID:9256449, GO:0005814=GO_REF:0000019, GO:0005509=GO_REF:0000002, GO:0032391=GO_REF:0000019, GO:0005932=GO_REF:0000019, GO:0045111=GO_REF:0000052, GO:0031683=GO_REF:0000019, GO:0051301=GO_REF:0000037} O15182 Centrin-3 protein 20110516 {GO:0008017=IEA, GO:0005813=IDA, GO:0007067=IEA, GO:0005737=IDA, GO:0007098=TAS, GO:0005814=IEA, GO:0005509=IEA, GO:0032391=IEA, GO:0005932=IEA, GO:0045111=IDA, GO:0031683=IEA, GO:0051301=IEA} cell division, centrosome cycle, mitosis centriole, centrosome, cytoplasm, intermediate filament cytoskeleton, microtubule basal body, photoreceptor connecting cilium G-protein beta/gamma-subunit complex binding, calcium ion binding, microtubule binding Human CETP BHF-UCL UniProtKB {GO:0006629=Reactome:REACT_602, GO:0017127=PMID:2833496, GO:0070328=PMID:2833496, GO:0030301=PMID:2833496, GO:0044281=Reactome:REACT_111217, GO:0005615=PMID:3104518, GO:0008289=PMID:3818596, GO:0010874=PMID:16670775, GO:0015914=PMID:2833496, GO:0034364=PMID:3104518, GO:0015485=PMID:2833496, GO:0008203=PMID:2833496, GO:0042632=PMID:2586614, GO:0010745=PMID:16670775, GO:0043691=PMID:7583561, GO:0055088=PMID:3818596, GO:0031210=PMID:2833496, GO:0005576=Reactome:REACT_13803, GO:0005548=PMID:2833496, GO:0031982=PMID:2833496, GO:0006898=Reactome:REACT_6934, GO:0034372=PMID:2833496, GO:0034374=PMID:2833496, GO:0034375=PMID:2586614, GO:0006869=PMID:3818596, GO:0042157=Reactome:REACT_13621, GO:0006641=PMID:2833496, GO:0055091=PMID:2833496, GO:0046470=PMID:2833496, GO:0017129=PMID:2833496, GO:0005319=PMID:2833496} P11597 Cholesteryl ester transfer protein protein 20071220 {GO:0006629=TAS, GO:0017127=IDA, GO:0070328=IDA, GO:0030301=IDA, GO:0044281=TAS, GO:0005615=IDA, GO:0008289=IDA, GO:0010874=IMP, GO:0015914=IDA, GO:0034364=IDA, GO:0015485=IDA, GO:0008203=IDA, GO:0042632=IMP, GO:0010745=IC, GO:0043691=IC, GO:0055088=IDA, GO:0031210=IDA, GO:0005576=TAS, GO:0005548=IDA, GO:0031982=IDA, GO:0006898=TAS, GO:0034372=IDA, GO:0034374=IDA, GO:0034375=IMP, GO:0006869=IDA, GO:0042157=TAS, GO:0006641=IDA, GO:0055091=IDA, GO:0046470=IDA, GO:0017129=IDA, GO:0005319=IDA} cholesterol homeostasis, cholesterol metabolic process, cholesterol transport, high-density lipoprotein particle remodeling, lipid homeostasis, lipid metabolic process, lipid transport, lipoprotein metabolic process, low-density lipoprotein particle remodeling, negative regulation of macrophage derived foam cell differentiation, phosphatidylcholine metabolic process, phospholipid homeostasis, phospholipid transport, receptor-mediated endocytosis, regulation of cholesterol efflux, reverse cholesterol transport, small molecule metabolic process, triglyceride homeostasis, triglyceride metabolic process, very-low-density lipoprotein particle remodeling extracellular region, extracellular space, high-density lipoprotein particle, vesicle cholesterol binding, cholesterol transporter activity, lipid binding, lipid transporter activity, phosphatidylcholine binding, phospholipid transporter activity, triglyceride binding Human CFB Reactome UniProtKB {GO:0006957=Reactome:REACT_8001, GO:0030449=Reactome:REACT_118707, GO:0006956=Reactome:REACT_8024, GO:0005886=Reactome:REACT_118782, GO:0001848=PMID:11367526, GO:0004252=Reactome:REACT_7948, GO:0045087=Reactome:REACT_6802, GO:0006508=GO_REF:0000037, GO:0005576=Reactome:REACT_118727} P00751 Complement factor B protein 20060216 {GO:0006957=TAS, GO:0030449=TAS, GO:0006956=TAS, GO:0005886=TAS, GO:0001848=TAS, GO:0004252=TAS, GO:0045087=TAS, GO:0006508=IEA, GO:0005576=TAS} complement activation, complement activation, alternative pathway, innate immune response, proteolysis, regulation of complement activation extracellular region, plasma membrane complement binding, serine-type endopeptidase activity Human CFD Reactome UniProtKB {GO:0006957=Reactome:REACT_8001, GO:0006956=Reactome:REACT_8024, GO:0004252=GO_REF:0000002, GO:0007596=Reactome:REACT_604, GO:0045087=Reactome:REACT_6802, GO:0002576=Reactome:REACT_318, GO:0006508=GO_REF:0000037, GO:0030168=Reactome:REACT_798, GO:0008236=PMID:1374388, GO:0031093=Reactome:REACT_21351, GO:0005576=Reactome:REACT_21351, GO:0005615=GO_REF:0000019} P00746 Complement factor D protein 20130301 {GO:0006957=TAS, GO:0006956=TAS, GO:0004252=IEA, GO:0007596=TAS, GO:0045087=TAS, GO:0002576=TAS, GO:0006508=IEA, GO:0030168=TAS, GO:0008236=TAS, GO:0031093=TAS, GO:0005576=TAS, GO:0005615=IEA} blood coagulation, complement activation, complement activation, alternative pathway, innate immune response, platelet activation, platelet degranulation, proteolysis extracellular region, extracellular space, platelet alpha granule lumen serine-type endopeptidase activity, serine-type peptidase activity Human CFDP1 UniProtKB UniProtKB {GO:0008150=GO_REF:0000015, GO:0003674=GO_REF:0000015, GO:0043066=GO_REF:0000019, GO:0042127=GO_REF:0000019, GO:0008360=GO_REF:0000019, GO:0007275=GO_REF:0000037, GO:0005575=GO_REF:0000015, GO:0007155=GO_REF:0000019} Q9UEE9 Craniofacial development protein 1 protein 20061106 {GO:0008150=ND, GO:0003674=ND, GO:0043066=IEA, GO:0042127=IEA, GO:0008360=IEA, GO:0007275=IEA, GO:0005575=ND, GO:0007155=IEA} biological_process, cell adhesion, multicellular organismal development, negative regulation of apoptotic process, regulation of cell proliferation, regulation of cell shape cellular_component molecular_function Human CFH BHF-UCL UniProtKB {GO:0005515=PMID:18627465, GO:0006957=GO_REF:0000037, GO:0030449=Reactome:REACT_118707, GO:0006956=PMID:9312129, GO:0045087=Reactome:REACT_6802, GO:0043395=PMID:22471560, GO:0005576=Reactome:REACT_118710, GO:0008201=PMID:22471560, GO:0005615=PMID:9312129} P08603 Complement factor H protein 20121220 {GO:0005515=IPI, GO:0006957=IEA, GO:0030449=TAS, GO:0006956=TAS, GO:0045087=TAS, GO:0043395=IDA, GO:0005576=TAS, GO:0008201=IDA, GO:0005615=TAS} complement activation, complement activation, alternative pathway, innate immune response, regulation of complement activation extracellular region, extracellular space heparan sulfate proteoglycan binding, heparin binding, protein binding Human CFHR1 PINC UniProtKB {GO:0006956=PMID:1711047, GO:0005615=PMID:1711047} Q03591 Complement factor H-related protein 1 protein 20030904 {GO:0006956=TAS, GO:0005615=TAS} complement activation extracellular space Human CFHR2 UniProtKB UniProtKB {GO:0005576=GO_REF:0000039} P36980 Complement factor H-related protein 2 protein 20130413 {GO:0005576=IEA} extracellular region Human UniProtKB-SubCell:SL-0243 CFHR3 PINC UniProtKB {GO:0005615=PMID:8428964} Q02985 Complement factor H-related protein 3 protein 20030904 {GO:0005615=TAS} extracellular space Human CFHR4 GOC UniProtKB {GO:0006869=PMID:9038172, GO:0005576=GO_REF:0000039, GO:0005319=PMID:9038172} Q92496 Complement factor H-related protein 4 protein 20130413 {GO:0006869=TAS, GO:0005576=IEA, GO:0005319=TAS} lipid transport extracellular region lipid transporter activity Human CFHR5 UniProtKB UniProtKB {GO:0006957=PMID:11058592, GO:0005576=PMID:11058592} Q9BXR6 Complement factor H-related protein 5 protein 20010921 {GO:0006957=NAS, GO:0005576=NAS} complement activation, alternative pathway extracellular region Human CFI Reactome UniProtKB {GO:0030449=Reactome:REACT_118707, GO:0004252=GO_REF:0000002, GO:0016020=GO_REF:0000002, GO:0045087=Reactome:REACT_6802, GO:0006958=GO_REF:0000037, GO:0006508=GO_REF:0000037, GO:0005576=Reactome:REACT_118844, GO:0005615=GO_REF:0000039, GO:0046872=GO_REF:0000037, GO:0005044=GO_REF:0000002} P05156 Complement factor I protein 20101013 {GO:0030449=TAS, GO:0004252=IEA, GO:0016020=IEA, GO:0045087=TAS, GO:0006958=IEA, GO:0006508=IEA, GO:0005576=TAS, GO:0005615=IEA, GO:0046872=IEA, GO:0005044=IEA} complement activation, classical pathway, innate immune response, proteolysis, regulation of complement activation extracellular region, extracellular space, membrane metal ion binding, scavenger receptor activity, serine-type endopeptidase activity Human CFL1 IntAct UniProtKB {GO:0005515=PMID:16713569, GO:0030036=PMID:10436159, GO:0001755=GO_REF:0000019, GO:0030010=GO_REF:0000019, GO:0005634=PMID:16130169, GO:0007266=PMID:10436159, GO:0015629=GO_REF:0000002, GO:0016363=GO_REF:0000039, GO:0000910=GO_REF:0000019, GO:0005737=PMID:16130169, GO:0007411=Reactome:REACT_18266, GO:0030836=GO_REF:0000019, GO:0007010=PMID:21834987, GO:0022604=PMID:21834987, GO:0030042=GO_REF:0000002, GO:0043200=GO_REF:0000019, GO:0043066=PMID:16130169, GO:0031258=GO_REF:0000039, GO:0030168=Reactome:REACT_798, GO:0003779=GO_REF:0000037, GO:0032587=GO_REF:0000039, GO:0009615=PMID:16548883, GO:0001842=GO_REF:0000019, GO:0007596=Reactome:REACT_604, GO:0045087=Reactome:REACT_6802, GO:0002576=Reactome:REACT_318, GO:0006468=GO_REF:0000019, GO:0030864=GO_REF:0000019, GO:0038096=Reactome:REACT_160123} P23528 Cofilin-1 protein 20130415 {GO:0005515=IPI, GO:0030036=TAS, GO:0001755=IEA, GO:0030010=IEA, GO:0005634=TAS, GO:0007266=TAS, GO:0015629=IEA, GO:0016363=IEA, GO:0000910=IEA, GO:0005737=TAS, GO:0007411=TAS, GO:0030836=IEA, GO:0007010=IMP, GO:0022604=IMP, GO:0030042=IEA, GO:0043200=IEA, GO:0043066=TAS, GO:0031258=IEA, GO:0030168=TAS, GO:0003779=IEA, GO:0032587=IEA, GO:0009615=IEP, GO:0001842=IEA, GO:0007596=TAS, GO:0045087=TAS, GO:0002576=TAS, GO:0006468=IEA, GO:0030864=IEA, GO:0038096=TAS} Fc-gamma receptor signaling pathway involved in phagocytosis, Rho protein signal transduction, actin cytoskeleton organization, actin filament depolymerization, axon guidance, blood coagulation, cytokinesis, cytoskeleton organization, establishment of cell polarity, innate immune response, negative regulation of apoptotic process, neural crest cell migration, neural fold formation, platelet activation, platelet degranulation, positive regulation of actin filament depolymerization, protein phosphorylation, regulation of cell morphogenesis, response to amino acid stimulus, response to virus actin cytoskeleton, cortical actin cytoskeleton, cytoplasm, lamellipodium membrane, nuclear matrix, nucleus, ruffle membrane actin binding, protein binding Human UniProtKB:P54253 CFL2 IntAct UniProtKB {GO:0005515=PMID:16189514, GO:0005737=GO_REF:0000037, GO:0030042=GO_REF:0000002, GO:0003779=GO_REF:0000037, GO:0015629=GO_REF:0000002, GO:0016363=GO_REF:0000039} Q9Y281 Cofilin-2 protein 20130415 {GO:0005515=IPI, GO:0005737=IEA, GO:0030042=IEA, GO:0003779=IEA, GO:0015629=IEA, GO:0016363=IEA} actin filament depolymerization actin cytoskeleton, cytoplasm, nuclear matrix actin binding, protein binding Human UniProtKB:P63261 CFLAR GOC UniProtKB {GO:0005515=PMID:9208847, GO:2001237=PMID:22266862, GO:0043066=PMID:18202225, GO:0006915=GO_REF:0000037, GO:1901740=GO_REF:0000024, GO:0014732=GO_REF:0000024, GO:0042981=GO_REF:0000002, GO:0043085=PMID:9208847, GO:0002020=PMID:9208847, GO:0004197=GO_REF:0000002, GO:0005737=PMID:18073330, GO:0007519=GO_REF:0000024, GO:0019048=GO_REF:0000037, GO:0006508=GO_REF:0000002, GO:0043403=GO_REF:0000024, GO:0014842=GO_REF:0000024, GO:0043123=PMID:12761501, GO:0014866=GO_REF:0000024} O15519 CASP8 and FADD-like apoptosis regulator protein 20130413 {GO:0005515=IPI, GO:2001237=IMP, GO:0043066=IMP, GO:0006915=IEA, GO:1901740=ISS, GO:0014732=ISS, GO:0042981=IEA, GO:0043085=IDA, GO:0002020=IPI, GO:0004197=IEA, GO:0005737=IDA, GO:0007519=ISS, GO:0019048=IEA, GO:0006508=IEA, GO:0043403=ISS, GO:0014842=ISS, GO:0043123=IEP, GO:0014866=ISS} apoptotic process, negative regulation of apoptotic process, negative regulation of extrinsic apoptotic signaling pathway, negative regulation of myoblast fusion, positive regulation of I-kappaB kinase/NF-kappaB cascade, positive regulation of catalytic activity, proteolysis, regulation of apoptotic process, regulation of satellite cell proliferation, skeletal muscle atrophy, skeletal muscle tissue development, skeletal muscle tissue regeneration, skeletal myofibril assembly, virus-host interaction cytoplasm cysteine-type endopeptidase activity, protease binding, protein binding Human CFP Reactome UniProtKB {GO:0006957=Reactome:REACT_8001, GO:0030449=Reactome:REACT_118707, GO:0006956=Reactome:REACT_8024, GO:0006955=PMID:8530058, GO:0045087=Reactome:REACT_6802, GO:0005576=Reactome:REACT_118641, GO:0005615=PMID:8530058, GO:0042742=PMID:8530058} P27918 Properdin protein 20130301 {GO:0006957=TAS, GO:0030449=TAS, GO:0006956=TAS, GO:0006955=TAS, GO:0045087=TAS, GO:0005576=TAS, GO:0005615=TAS, GO:0042742=TAS} complement activation, complement activation, alternative pathway, defense response to bacterium, immune response, innate immune response, regulation of complement activation extracellular region, extracellular space Human CFTR IntAct UniProtKB {GO:0005515=PMID:22121115, GO:0030321=GO_REF:0000019, GO:0006695=GO_REF:0000019, GO:0043627=GO_REF:0000019, GO:0005886=Reactome:REACT_111162, GO:0030324=GO_REF:0000019, GO:0043434=GO_REF:0000019, GO:0042626=GO_REF:0000002, GO:0030301=GO_REF:0000019, GO:0031205=PMID:9792704, GO:0005254=PMID:22178883, GO:0032870=GO_REF:0000019, GO:0016323=PMID:11707463, GO:0016324=PMID:12801959, GO:0042311=GO_REF:0000019, GO:0045909=GO_REF:0000019, GO:0006810=PMID:7541313, GO:0006833=GO_REF:0000019, GO:0034097=GO_REF:0000019, GO:0016887=GO_REF:0000002, GO:0030659=GO_REF:0000019, GO:0005260=PMID:11707463, GO:0005224=PMID:10581360, GO:0007585=PMID:9875854, GO:0042493=GO_REF:0000019, GO:0034707=GO_REF:0000037, GO:0030165=PMID:11707463, GO:0055085=Reactome:REACT_15518, GO:0005524=GO_REF:0000037, GO:0019869=PMID:22178883, GO:0043234=PMID:17462998, GO:0005902=GO_REF:0000019, GO:0031901=GO_REF:0000039, GO:0015701=GO_REF:0000019, GO:0016021=GO_REF:0000002, GO:0019899=PMID:19398555, GO:0015705=GO_REF:0000019, GO:0005769=PMID:19398555} P13569 Cystic fibrosis transmembrane conductance regulator protein 20130415 {GO:0005515=IPI, GO:0030321=IEA, GO:0006695=IEA, GO:0043627=IEA, GO:0005886=TAS, GO:0030324=IEA, GO:0043434=IEA, GO:0042626=IEA, GO:0030301=IEA, GO:0031205=IDA, GO:0005254=IDA, GO:0032870=IEA, GO:0016323=NAS, GO:0016324=IDA, GO:0042311=IEA, GO:0045909=IEA, GO:0006810=TAS, GO:0006833=IEA, GO:0034097=IEA, GO:0016887=IEA, GO:0030659=IEA, GO:0005260=NAS, GO:0005224=TAS, GO:0007585=TAS, GO:0042493=IEA, GO:0034707=IEA, GO:0030165=IDA, GO:0055085=TAS, GO:0005524=IEA, GO:0019869=IDA, GO:0043234=IDA, GO:0005902=IEA, GO:0031901=IEA, GO:0015701=IEA, GO:0016021=IEA, GO:0019899=IPI, GO:0015705=IEA, GO:0005769=IDA} bicarbonate transport, cellular response to hormone stimulus, cholesterol biosynthetic process, cholesterol transport, iodide transport, lung development, positive regulation of vasodilation, respiratory gaseous exchange, response to cytokine stimulus, response to drug, response to estrogen stimulus, response to peptide hormone stimulus, transepithelial chloride transport, transmembrane transport, transport, vasodilation, water transport apical plasma membrane, basolateral plasma membrane, chloride channel complex, cytoplasmic vesicle membrane, early endosome, early endosome membrane, endoplasmic reticulum Sec complex, integral to membrane, microvillus, plasma membrane, protein complex ATP binding, ATP-binding and phosphorylation-dependent chloride channel activity, ATPase activity, ATPase activity, coupled to transmembrane movement of substances, PDZ domain binding, channel-conductance-controlling ATPase activity, chloride channel activity, chloride channel inhibitor activity, enzyme binding, protein binding Human UniProtKB:Q96RN1 CGA BHF-UCL UniProtKB {GO:0005515=PMID:15662415, GO:0008406=GO_REF:0000019, GO:0046621=GO_REF:0000019, GO:0008284=PMID:20613903, GO:0030335=PMID:20613903, GO:0007267=PMID:481597, GO:0005576=Reactome:REACT_22268, GO:0030878=GO_REF:0000019, GO:0032870=GO_REF:0000019, GO:0007165=PMID:481597, GO:0048589=GO_REF:0000019, GO:0016486=Reactome:REACT_15452, GO:0046884=GO_REF:0000019, GO:0032275=GO_REF:0000019, GO:0005179=GO_REF:0000037, GO:0006590=GO_REF:0000019, GO:0044267=Reactome:REACT_17015} P01215 Glycoprotein hormones alpha chain protein 20120821 {GO:0005515=IPI, GO:0008406=IEA, GO:0046621=IEA, GO:0008284=NAS, GO:0030335=NAS, GO:0007267=TAS, GO:0005576=TAS, GO:0030878=IEA, GO:0032870=IEA, GO:0007165=TAS, GO:0048589=IEA, GO:0016486=TAS, GO:0046884=IEA, GO:0032275=IEA, GO:0005179=IEA, GO:0006590=IEA, GO:0044267=TAS} cell-cell signaling, cellular protein metabolic process, cellular response to hormone stimulus, developmental growth, follicle-stimulating hormone secretion, gonad development, luteinizing hormone secretion, negative regulation of organ growth, peptide hormone processing, positive regulation of cell migration, positive regulation of cell proliferation, signal transduction, thyroid gland development, thyroid hormone generation extracellular region hormone activity, protein binding Human CGB Reactome UniProtKB {GO:0007165=PMID:10468638, GO:0016486=Reactome:REACT_15452, GO:0005179=GO_REF:0000037, GO:0007267=PMID:6194155, GO:0006915=PMID:7723844, GO:0005576=Reactome:REACT_15432, GO:0007292=PMID:10468638, GO:0044267=Reactome:REACT_17015} P01233 Choriogonadotropin subunit beta protein 20081001 {GO:0007165=TAS, GO:0016486=TAS, GO:0005179=IEA, GO:0007267=TAS, GO:0006915=TAS, GO:0005576=TAS, GO:0007292=TAS, GO:0044267=TAS} apoptotic process, cell-cell signaling, cellular protein metabolic process, female gamete generation, peptide hormone processing, signal transduction extracellular region hormone activity Human CGB5 null null {} null null null null {} null null null CGGBP1 HPA UniProtKB {GO:0006355=GO_REF:0000037, GO:0003690=PMID:8626781, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0006351=GO_REF:0000037} Q9UFW8 CGG triplet repeat-binding protein 1 protein 20110516 {GO:0006355=IEA, GO:0003690=TAS, GO:0005730=IDA, GO:0005634=IDA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleolus, nucleus double-stranded DNA binding NOT Human CGN Reactome UniProtKB {GO:0005515=PMID:11042084, GO:0008150=GO_REF:0000015, GO:0043296=GO_REF:0000019, GO:0003774=GO_REF:0000002, GO:0030054=Reactome:REACT_121319, GO:0007179=Reactome:REACT_120726, GO:0003779=GO_REF:0000024, GO:0005923=PMID:22006950, GO:0016459=GO_REF:0000002} Q9P2M7 Cingulin protein 20120223 {GO:0005515=IPI, GO:0008150=ND, GO:0043296=IEA, GO:0003774=IEA, GO:0030054=TAS, GO:0007179=TAS, GO:0003779=ISS, GO:0005923=IDA, GO:0016459=IEA} biological_process, transforming growth factor beta receptor signaling pathway apical junction complex, cell junction, myosin complex, tight junction actin binding, motor activity, protein binding Human CGNL1 UniProtKB UniProtKB {GO:0003774=GO_REF:0000002, GO:0005923=GO_REF:0000039, GO:0016459=GO_REF:0000002} Q0VF96 Cingulin-like protein 1 protein 20130413 {GO:0003774=IEA, GO:0005923=IEA, GO:0016459=IEA} myosin complex, tight junction motor activity Human UniProtKB-SubCell:SL-0265 CGRRF1 PINC UniProtKB {GO:0008285=PMID:8968090, GO:0006950=PMID:8968090, GO:0005634=GO_REF:0000039, GO:0007050=GO_REF:0000037, GO:0008270=GO_REF:0000002} Q99675 Cell growth regulator with RING finger domain protein 1 protein 20030904 {GO:0008285=TAS, GO:0006950=TAS, GO:0005634=IEA, GO:0007050=IEA, GO:0008270=IEA} cell cycle arrest, negative regulation of cell proliferation, response to stress nucleus zinc ion binding Human CH25H Reactome UniProtKB {GO:0006629=PMID:9852097, GO:0005506=GO_REF:0000002, GO:0001567=GO_REF:0000003, GO:0006699=Reactome:REACT_11054, GO:0008395=Reactome:REACT_10030, GO:0044281=Reactome:REACT_111217, GO:0005829=Reactome:REACT_10030, GO:0016126=GO_REF:0000037, GO:0005789=GO_REF:0000039, GO:0006633=GO_REF:0000002, GO:0008206=Reactome:REACT_11040, GO:0016021=GO_REF:0000037, GO:0008203=GO_REF:0000019} O95992 Cholesterol 25-hydroxylase protein 20130213 {GO:0006629=TAS, GO:0005506=IEA, GO:0001567=IEA, GO:0006699=TAS, GO:0008395=TAS, GO:0044281=TAS, GO:0005829=TAS, GO:0016126=IEA, GO:0005789=IEA, GO:0006633=IEA, GO:0008206=TAS, GO:0016021=IEA, GO:0008203=IEA} bile acid biosynthetic process, bile acid metabolic process, cholesterol metabolic process, fatty acid biosynthetic process, lipid metabolic process, small molecule metabolic process, sterol biosynthetic process cytosol, endoplasmic reticulum membrane, integral to membrane cholesterol 25-hydroxylase activity, iron ion binding, steroid hydroxylase activity Human CHAC1 IntAct UniProtKB {GO:0005515=PMID:16189514, GO:0006986=GO_REF:0000037, GO:0005802=GO_REF:0000024, GO:0045746=PMID:22445366, GO:0005794=GO_REF:0000039, GO:0007219=GO_REF:0000037, GO:0070059=PMID:19109178, GO:0005112=GO_REF:0000024, GO:0010955=PMID:22445366, GO:0005829=PMID:19109178, GO:0022008=GO_REF:0000024} Q9BUX1 Cation transport regulator-like protein 1 protein 20130415 {GO:0005515=IPI, GO:0006986=IEA, GO:0005802=ISS, GO:0045746=IMP, GO:0005794=IEA, GO:0007219=IEA, GO:0070059=IMP, GO:0005112=ISS, GO:0010955=IMP, GO:0005829=IDA, GO:0022008=ISS} Notch signaling pathway, intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress, negative regulation of Notch signaling pathway, negative regulation of protein processing, neurogenesis, response to unfolded protein Golgi apparatus, cytosol, trans-Golgi network Notch binding, protein binding Human UniProtKB:Q9BQY4 CHAC2 UniProtKB UniProtKB {GO:0008150=GO_REF:0000015, GO:0003674=GO_REF:0000015, GO:0005575=GO_REF:0000015} Q8WUX2 Cation transport regulator-like protein 2 protein 20080507 {GO:0008150=ND, GO:0003674=ND, GO:0005575=ND} biological_process cellular_component molecular_function Human CHAD UniProtKB UniProtKB {GO:0001502=GO_REF:0000019, GO:0005578=GO_REF:0000029, GO:0001558=GO_REF:0000029, GO:0005201=GO_REF:0000029} O15335 Chondroadherin protein 20021106 {GO:0001502=IEA, GO:0005578=TAS, GO:0001558=NAS, GO:0005201=NAS} cartilage condensation, regulation of cell growth proteinaceous extracellular matrix extracellular matrix structural constituent Human CHAF1A BHF-UCL UniProtKB {GO:0005515=PMID:21570500, GO:0006355=GO_REF:0000037, GO:0033186=PMID:8858152, GO:0070087=PMID:15882967, GO:0006335=PMID:7600578, GO:0071778=PMID:12837248, GO:0006351=GO_REF:0000037, GO:0006260=GO_REF:0000037, GO:0007049=GO_REF:0000037, GO:0006281=GO_REF:0000037, GO:0006461=PMID:7600578, GO:0031497=PMID:8858152, GO:0003682=PMID:7600578, GO:0051082=PMID:7600578} Q13111 Chromatin assembly factor 1 subunit A protein 20100127 {GO:0005515=IPI, GO:0006355=IEA, GO:0033186=IDA, GO:0070087=IPI, GO:0006335=TAS, GO:0071778=IDA, GO:0006351=IEA, GO:0006260=IEA, GO:0007049=IEA, GO:0006281=IEA, GO:0006461=TAS, GO:0031497=IDA, GO:0003682=TAS, GO:0051082=TAS} DNA repair, DNA replication, DNA replication-dependent nucleosome assembly, cell cycle, chromatin assembly, protein complex assembly, regulation of transcription, DNA-dependent, transcription, DNA-dependent CAF-1 complex, WINAC complex chromatin binding, chromo shadow domain binding, protein binding, unfolded protein binding Human UniProtKB:P45973 CHAF1B HPA UniProtKB {GO:0006355=GO_REF:0000037, GO:0033186=PMID:8858152, GO:0005730=GO_REF:0000052, GO:0006335=PMID:7600578, GO:0005634=GO_REF:0000052, GO:0006351=GO_REF:0000037, GO:0005829=PMID:16780588, GO:0006260=GO_REF:0000037, GO:0042393=PMID:7600578, GO:0007049=GO_REF:0000037, GO:0005737=PMID:9614144, GO:0006461=PMID:7600578, GO:0006281=GO_REF:0000037, GO:0031497=PMID:8858152, GO:0003682=PMID:7600578, GO:0005654=PMID:16780588, GO:0051082=PMID:7600578} Q13112 Chromatin assembly factor 1 subunit B protein 20111111 {GO:0006355=IEA, GO:0033186=IDA, GO:0005730=IDA, GO:0006335=TAS, GO:0005634=IDA, GO:0006351=IEA, GO:0005829=IDA, GO:0006260=IEA, GO:0042393=NAS, GO:0007049=IEA, GO:0005737=NAS, GO:0006461=TAS, GO:0006281=IEA, GO:0031497=IDA, GO:0003682=TAS, GO:0005654=IDA, GO:0051082=TAS} DNA repair, DNA replication, DNA replication-dependent nucleosome assembly, cell cycle, chromatin assembly, protein complex assembly, regulation of transcription, DNA-dependent, transcription, DNA-dependent CAF-1 complex, cytoplasm, cytosol, nucleolus, nucleoplasm, nucleus chromatin binding, histone binding, unfolded protein binding NOT Human CHAMP1 HPA UniProtKB {GO:0005515=PMID:21063390, GO:0000793=PMID:21063390, GO:0034501=PMID:21063390, GO:0005819=PMID:21063390, GO:0005730=GO_REF:0000052, GO:0035372=PMID:21063390, GO:0005634=GO_REF:0000052, GO:0031134=PMID:21063390, GO:0003676=GO_REF:0000002, GO:0005737=GO_REF:0000037, GO:0051315=PMID:21063390, GO:0000777=PMID:21063390, GO:0008270=GO_REF:0000002} Q96JM3 Chromosome alignment-maintaining phosphoprotein 1 protein 20101115 {GO:0005515=IPI, GO:0000793=IDA, GO:0034501=IMP, GO:0005819=IDA, GO:0005730=IDA, GO:0035372=IMP, GO:0005634=IDA, GO:0031134=IMP, GO:0003676=IEA, GO:0005737=IEA, GO:0051315=IMP, GO:0000777=IDA, GO:0008270=IEA} attachment of spindle microtubules to kinetochore involved in mitotic sister chromatid segregation, protein localization to kinetochore, protein localization to microtubule, sister chromatid biorientation condensed chromosome, condensed chromosome kinetochore, cytoplasm, nucleolus, nucleus, spindle nucleic acid binding, protein binding, zinc ion binding NOT Human CHAT Reactome UniProtKB {GO:0030424=GO_REF:0000019, GO:0016746=GO_REF:0000038, GO:0004102=GO_REF:0000003, GO:0043179=GO_REF:0000019, GO:0007268=Reactome:REACT_13685, GO:0005634=PMID:10861222, GO:0044281=Reactome:REACT_111217, GO:0007274=GO_REF:0000019, GO:0007269=Reactome:REACT_13723, GO:0016358=GO_REF:0000019, GO:0005829=Reactome:REACT_15484, GO:0005739=GO_REF:0000019, GO:0005737=PMID:10861222, GO:0007529=GO_REF:0000019, GO:0007628=GO_REF:0000019, GO:0043025=GO_REF:0000019, GO:0007622=GO_REF:0000019, GO:0042136=GO_REF:0000037, GO:0006644=Reactome:REACT_120870, GO:0046474=Reactome:REACT_121401, GO:0006656=Reactome:REACT_121238} P28329 Choline O-acetyltransferase protein 20130301 {GO:0030424=IEA, GO:0016746=IEA, GO:0004102=IEA, GO:0043179=IEA, GO:0007268=TAS, GO:0005634=TAS, GO:0044281=TAS, GO:0007274=IEA, GO:0007269=TAS, GO:0016358=IEA, GO:0005829=TAS, GO:0005739=IEA, GO:0005737=TAS, GO:0007529=IEA, GO:0007628=IEA, GO:0043025=IEA, GO:0007622=IEA, GO:0042136=IEA, GO:0006644=TAS, GO:0046474=TAS, GO:0006656=TAS} adult walking behavior, dendrite development, establishment of synaptic specificity at neuromuscular junction, glycerophospholipid biosynthetic process, neuromuscular synaptic transmission, neurotransmitter biosynthetic process, neurotransmitter secretion, phosphatidylcholine biosynthetic process, phospholipid metabolic process, rhythmic behavior, rhythmic excitation, small molecule metabolic process, synaptic transmission axon, cytoplasm, cytosol, mitochondrion, neuronal cell body, nucleus choline O-acetyltransferase activity, transferase activity, transferring acyl groups Human CHCHD1 HPA UniProtKB {GO:0005515=PMID:22190034, GO:0005739=GO_REF:0000052, GO:0005737=GO_REF:0000052, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052} Q96BP2 Coiled-coil-helix-coiled-coil-helix domain-containing protein 1 protein 20111111 {GO:0005515=IPI, GO:0005739=IDA, GO:0005737=IDA, GO:0005730=IDA, GO:0005634=IDA} cytoplasm, mitochondrion, nucleolus, nucleus protein binding Human CHCHD2 UniProtKB UniProtKB {GO:0005739=GO_REF:0000039} Q9Y6H1 Coiled-coil-helix-coiled-coil-helix domain-containing protein 2, mitochondrial protein 20130413 {GO:0005739=IEA} mitochondrion Human UniProtKB-SubCell:SL-0173 CHCHD3 HPA UniProtKB {GO:0005515=PMID:19389623, GO:0005739=GO_REF:0000052, GO:0005737=PMID:22567091, GO:0032947=GO_REF:0000024, GO:0008053=PMID:21081504, GO:0019902=PMID:19389623, GO:0005743=GO_REF:0000024, GO:0007007=PMID:21081504, GO:0005634=PMID:22567091, GO:0000122=PMID:22567091, GO:0001227=PMID:22567091} Q9NX63 Coiled-coil-helix-coiled-coil-helix domain-containing protein 3, mitochondrial protein 20111111 {GO:0005515=IPI, GO:0005739=IDA, GO:0005737=IDA, GO:0032947=ISS, GO:0008053=IMP, GO:0019902=IDA, GO:0005743=ISS, GO:0007007=IMP, GO:0005634=IDA, GO:0000122=IDA, GO:0001227=IDA} inner mitochondrial membrane organization, mitochondrial fusion, negative regulation of transcription from RNA polymerase II promoter cytoplasm, mitochondrial inner membrane, mitochondrion, nucleus RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription, phosphatase binding, protein binding, protein complex scaffold Human CHCHD4 Reactome UniProtKB {GO:0005758=PMID:16185709, GO:0006626=Reactome:REACT_118595, GO:0015035=PMID:19182799, GO:0051084=PMID:21059946, GO:0044267=Reactome:REACT_17015, GO:0045041=PMID:16185709, GO:0022417=PMID:21059946} Q8N4Q1 Mitochondrial intermembrane space import and assembly protein 40 protein 20110427 {GO:0005758=IDA, GO:0006626=TAS, GO:0015035=IMP, GO:0051084=IMP, GO:0044267=TAS, GO:0045041=IMP, GO:0022417=IMP} 'de novo' posttranslational protein folding, cellular protein metabolic process, protein import into mitochondrial intermembrane space, protein maturation by protein folding, protein targeting to mitochondrion mitochondrial intermembrane space protein disulfide oxidoreductase activity Human CHCHD6 UniProtKB UniProtKB {GO:0005739=PMID:22228767, GO:0005515=PMID:22228767, GO:0005743=PMID:22228767, GO:0042407=PMID:22228767, GO:0006974=PMID:22228767} Q9BRQ6 Coiled-coil-helix-coiled-coil-helix domain-containing protein 6, mitochondrial protein 20120228 {GO:0005739=IMP, GO:0005515=IPI, GO:0005743=IDA, GO:0042407=IMP, GO:0006974=IDA} cristae formation, response to DNA damage stimulus mitochondrial inner membrane, mitochondrion protein binding Human UniProtKB:Q9NRI5 CHD1 PINC UniProtKB {GO:0005737=GO_REF:0000039, GO:0004003=PMID:9326634, GO:0006357=PMID:9326634, GO:0005634=GO_REF:0000039, GO:0006338=GO_REF:0000019, GO:0035064=PMID:21029866, GO:0005524=GO_REF:0000037, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} O14646 Chromodomain-helicase-DNA-binding protein 1 protein 20030904 {GO:0005737=IEA, GO:0004003=TAS, GO:0006357=TAS, GO:0005634=IEA, GO:0006338=IEA, GO:0035064=IDA, GO:0005524=IEA, GO:0003677=IEA, GO:0006351=IEA} chromatin remodeling, regulation of transcription from RNA polymerase II promoter, transcription, DNA-dependent cytoplasm, nucleus ATP binding, ATP-dependent DNA helicase activity, DNA binding, methylated histone residue binding Human CHD1L HPA UniProtKB {GO:0005515=PMID:19661379, GO:0006200=PMID:19661379, GO:0005886=GO_REF:0000052, GO:0004386=GO_REF:0000002, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0003676=GO_REF:0000002, GO:0005524=GO_REF:0000037, GO:0003677=GO_REF:0000002, GO:0006974=PMID:19661379, GO:0005737=GO_REF:0000052, GO:0004003=PMID:19661379, GO:0006281=PMID:19661379, GO:0000166=PMID:19661379, GO:0006338=PMID:19661379, GO:0016887=PMID:19661379} Q86WJ1 Chromodomain-helicase-DNA-binding protein 1-like protein 20101115 {GO:0005515=IPI, GO:0006200=IMP, GO:0005886=IDA, GO:0004386=IEA, GO:0005730=IDA, GO:0005634=IDA, GO:0003676=IEA, GO:0005524=IEA, GO:0003677=IEA, GO:0006974=IDA, GO:0005737=IDA, GO:0004003=TAS, GO:0006281=TAS, GO:0000166=IDA, GO:0006338=IDA, GO:0016887=IMP} ATP catabolic process, DNA repair, chromatin remodeling, response to DNA damage stimulus cytoplasm, nucleolus, nucleus, plasma membrane ATP binding, ATP-dependent DNA helicase activity, ATPase activity, DNA binding, helicase activity, nucleic acid binding, nucleotide binding, protein binding Human CHD2 PINC UniProtKB {GO:0004003=PMID:9326634, GO:0006357=PMID:9326634, GO:0004386=GO_REF:0000002, GO:0005634=GO_REF:0000039, GO:0003676=GO_REF:0000002, GO:0005524=GO_REF:0000037, GO:0003677=GO_REF:0000037} O14647 Chromodomain-helicase-DNA-binding protein 2 protein 20030904 {GO:0004003=TAS, GO:0006357=TAS, GO:0004386=IEA, GO:0005634=IEA, GO:0003676=IEA, GO:0005524=IEA, GO:0003677=IEA} regulation of transcription from RNA polymerase II promoter nucleus ATP binding, ATP-dependent DNA helicase activity, DNA binding, helicase activity, nucleic acid binding Human CHD3 HPA UniProtKB {GO:0005515=PMID:20676135, GO:0008026=GO_REF:0000002, GO:0005813=PMID:17626165, GO:0006355=PMID:9688266, GO:0006357=PMID:9326634, GO:0004386=PMID:9688266, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0016818=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0005524=GO_REF:0000037, GO:0006351=GO_REF:0000037, GO:0006333=GO_REF:0000019, GO:0051297=PMID:17626165, GO:0005737=PMID:17626165, GO:0004003=PMID:9326634, GO:0016581=PMID:17827154, GO:0008270=PMID:9688266, GO:0007051=PMID:17626165, GO:0045111=GO_REF:0000052, GO:0016568=GO_REF:0000037} Q12873 Chromodomain-helicase-DNA-binding protein 3 protein 20120912 {GO:0005515=IPI, GO:0008026=IEA, GO:0005813=IDA, GO:0006355=NAS, GO:0006357=TAS, GO:0004386=NAS, GO:0005730=IDA, GO:0005634=IDA, GO:0016818=IEA, GO:0003677=IEA, GO:0005524=IEA, GO:0006351=IEA, GO:0006333=IEA, GO:0051297=IDA, GO:0005737=IDA, GO:0004003=TAS, GO:0016581=IDA, GO:0008270=NAS, GO:0007051=IDA, GO:0045111=IDA, GO:0016568=IEA} centrosome organization, chromatin assembly or disassembly, chromatin modification, regulation of transcription from RNA polymerase II promoter, regulation of transcription, DNA-dependent, spindle organization, transcription, DNA-dependent NuRD complex, centrosome, cytoplasm, intermediate filament cytoskeleton, nucleolus, nucleus ATP binding, ATP-dependent DNA helicase activity, ATP-dependent helicase activity, DNA binding, helicase activity, hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides, protein binding, zinc ion binding Human CHD4 HPA UniProtKB {GO:0001103=PMID:22926524, GO:0008026=GO_REF:0000002, GO:0005515=PMID:17314511, GO:0005813=PMID:17626165, GO:0006355=GO_REF:0000002, GO:0006357=PMID:9326634, GO:0005634=GO_REF:0000052, GO:0016818=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0005524=GO_REF:0000037, GO:0006351=GO_REF:0000037, GO:0005737=PMID:17626165, GO:0004003=PMID:9326634, GO:0016581=PMID:19644445, GO:0008270=GO_REF:0000002, GO:0008134=GO_REF:0000019, GO:0016568=GO_REF:0000037} Q14839 Chromodomain-helicase-DNA-binding protein 4 protein 20111111 {GO:0001103=IPI, GO:0008026=IEA, GO:0005515=IPI, GO:0005813=IDA, GO:0006355=IEA, GO:0006357=TAS, GO:0005634=IDA, GO:0016818=IEA, GO:0003677=IEA, GO:0005524=IEA, GO:0006351=IEA, GO:0005737=IDA, GO:0004003=TAS, GO:0016581=IDA, GO:0008270=IEA, GO:0008134=IEA, GO:0016568=IEA} chromatin modification, regulation of transcription from RNA polymerase II promoter, regulation of transcription, DNA-dependent, transcription, DNA-dependent NuRD complex, centrosome, cytoplasm, nucleus ATP binding, ATP-dependent DNA helicase activity, ATP-dependent helicase activity, DNA binding, RNA polymerase II repressing transcription factor binding, hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides, protein binding, transcription factor binding, zinc ion binding Human CHD5 UniProtKB UniProtKB {GO:0008026=GO_REF:0000002, GO:0006355=GO_REF:0000037, GO:0004386=GO_REF:0000002, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0016818=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0005524=GO_REF:0000037, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037, GO:0016568=GO_REF:0000037} Q8TDI0 Chromodomain-helicase-DNA-binding protein 5 protein 20130413 {GO:0008026=IEA, GO:0006355=IEA, GO:0004386=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0016818=IEA, GO:0003676=IEA, GO:0005524=IEA, GO:0003677=IEA, GO:0006351=IEA, GO:0016568=IEA} chromatin modification, regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus ATP binding, ATP-dependent helicase activity, DNA binding, helicase activity, hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides, nucleic acid binding, zinc ion binding Human UniProtKB-SubCell:SL-0191 CHD6 UniProtKB UniProtKB {GO:0008026=GO_REF:0000002, GO:0006355=PMID:12592387, GO:0003682=PMID:12592387, GO:0006338=PMID:12592387, GO:0005634=PMID:12592387, GO:0005524=GO_REF:0000037, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037, GO:0007399=PMID:12592387} Q8TD26 Chromodomain-helicase-DNA-binding protein 6 protein 20030424 {GO:0008026=IEA, GO:0006355=NAS, GO:0003682=NAS, GO:0006338=NAS, GO:0005634=NAS, GO:0005524=IEA, GO:0003677=IEA, GO:0006351=IEA, GO:0007399=NAS} chromatin remodeling, nervous system development, regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus ATP binding, ATP-dependent helicase activity, DNA binding, chromatin binding Human CHD7 BHF-UCL UniProtKB {GO:0060123=PMID:9556299, GO:0005515=PMID:20453063, GO:0016817=GO_REF:0000002, GO:0060041=PMID:15300250, GO:0008015=GO_REF:0000019, GO:0007605=GO_REF:0000019, GO:0048844=GO_REF:0000019, GO:0005634=PMID:17299439, GO:0048752=GO_REF:0000019, GO:0007512=GO_REF:0000019, GO:0007628=GO_REF:0000019, GO:0060021=PMID:15300250, GO:0043010=GO_REF:0000019, GO:0040018=GO_REF:0000019, GO:0048806=PMID:15300250, GO:0006355=PMID:17937444, GO:0042472=PMID:15300250, GO:0021545=PMID:9556299, GO:0004386=GO_REF:0000037, GO:0007417=PMID:9556299, GO:0001701=PMID:15300250, GO:0003677=GO_REF:0000037, GO:0005524=GO_REF:0000037, GO:0006351=GO_REF:0000037, GO:0001501=PMID:16155193, GO:0003007=PMID:15300250, GO:0030217=PMID:17684005, GO:0050890=PMID:16155193, GO:0003682=PMID:17299439, GO:0060324=PMID:15300250, GO:0035116=GO_REF:0000019, GO:0060173=PMID:17937444, GO:0030540=GO_REF:0000019, GO:0043584=PMID:15300250, GO:0016568=GO_REF:0000037} Q9P2D1 Chromodomain-helicase-DNA-binding protein 7 protein 20080923 {GO:0060123=IMP, GO:0005515=IPI, GO:0016817=IEA, GO:0060041=IMP, GO:0008015=IEA, GO:0007605=IEA, GO:0048844=IEA, GO:0005634=TAS, GO:0048752=IEA, GO:0007512=IEA, GO:0007628=IEA, GO:0060021=IMP, GO:0043010=IEA, GO:0040018=IEA, GO:0048806=IMP, GO:0006355=NAS, GO:0042472=IMP, GO:0021545=IMP, GO:0004386=IEA, GO:0007417=IMP, GO:0001701=IMP, GO:0003677=IEA, GO:0005524=IEA, GO:0006351=IEA, GO:0001501=IMP, GO:0003007=IMP, GO:0030217=IMP, GO:0050890=IMP, GO:0003682=TAS, GO:0060324=IMP, GO:0035116=IEA, GO:0060173=IMP, GO:0030540=IEA, GO:0043584=IMP, GO:0016568=IEA} T cell differentiation, adult heart development, adult walking behavior, artery morphogenesis, blood circulation, camera-type eye development, central nervous system development, chromatin modification, cognition, cranial nerve development, embryonic hindlimb morphogenesis, face development, female genitalia development, genitalia development, heart morphogenesis, in utero embryonic development, inner ear morphogenesis, limb development, nose development, palate development, positive regulation of multicellular organism growth, regulation of growth hormone secretion, regulation of transcription, DNA-dependent, retina development in camera-type eye, semicircular canal morphogenesis, sensory perception of sound, skeletal system development, transcription, DNA-dependent nucleus ATP binding, DNA binding, chromatin binding, helicase activity, hydrolase activity, acting on acid anhydrides, protein binding Human CHD8 GOC UniProtKB {GO:0005515=PMID:20453063, GO:0008013=PMID:18378692, GO:0030178=PMID:18378692, GO:0005634=PMID:20453063, GO:0035064=PMID:17938208, GO:0042393=GO_REF:0000024, GO:0002039=GO_REF:0000024, GO:0045944=PMID:17938208, GO:0071339=PMID:15960975, GO:0045945=PMID:17938208, GO:0032508=PMID:18378692, GO:0060070=PMID:18378692, GO:0008094=PMID:18378692, GO:0043066=GO_REF:0000019, GO:0043044=PMID:18378692, GO:0004386=GO_REF:0000002, GO:0001701=GO_REF:0000019, GO:0005524=PMID:18378692, GO:0003677=PMID:18378692, GO:0003678=PMID:18378692, GO:0006351=GO_REF:0000037, GO:0043234=PMID:18378692, GO:0045893=PMID:17938208, GO:0045892=PMID:18378692, GO:0070016=GO_REF:0000019} Q9HCK8 Chromodomain-helicase-DNA-binding protein 8 protein 20130413 {GO:0005515=IPI, GO:0008013=IDA, GO:0030178=IDA, GO:0005634=IDA, GO:0035064=IDA, GO:0042393=ISS, GO:0002039=ISS, GO:0045944=IMP, GO:0071339=IDA, GO:0045945=IMP, GO:0032508=IMP, GO:0060070=IDA, GO:0008094=IDA, GO:0043066=IEA, GO:0043044=IMP, GO:0004386=IEA, GO:0001701=IEA, GO:0005524=IDA, GO:0003677=IMP, GO:0003678=IMP, GO:0006351=IEA, GO:0043234=IDA, GO:0045893=IDA, GO:0045892=IMP, GO:0070016=IEA} ATP-dependent chromatin remodeling, DNA duplex unwinding, canonical Wnt receptor signaling pathway, in utero embryonic development, negative regulation of Wnt receptor signaling pathway, negative regulation of apoptotic process, negative regulation of transcription, DNA-dependent, positive regulation of transcription from RNA polymerase II promoter, positive regulation of transcription from RNA polymerase III promoter, positive regulation of transcription, DNA-dependent, transcription, DNA-dependent MLL1 complex, nucleus, protein complex ATP binding, DNA binding, DNA helicase activity, DNA-dependent ATPase activity, armadillo repeat domain binding, beta-catenin binding, helicase activity, histone binding, methylated histone residue binding, p53 binding, protein binding Human CHD9 Reactome UniProtKB {GO:0005737=GO_REF:0000039, GO:0006355=GO_REF:0000037, GO:0016817=GO_REF:0000002, GO:0004386=GO_REF:0000037, GO:0005654=Reactome:REACT_19175, GO:0005634=GO_REF:0000038, GO:0044281=Reactome:REACT_111217, GO:0005524=GO_REF:0000037, GO:0003677=GO_REF:0000037, GO:0044255=Reactome:REACT_22279, GO:0006351=GO_REF:0000037, GO:0016568=GO_REF:0000037} Q3L8U1 Chromodomain-helicase-DNA-binding protein 9 protein 20130301 {GO:0005737=IEA, GO:0006355=IEA, GO:0016817=IEA, GO:0004386=IEA, GO:0005654=TAS, GO:0005634=IEA, GO:0044281=TAS, GO:0005524=IEA, GO:0003677=IEA, GO:0044255=TAS, GO:0006351=IEA, GO:0016568=IEA} cellular lipid metabolic process, chromatin modification, regulation of transcription, DNA-dependent, small molecule metabolic process, transcription, DNA-dependent cytoplasm, nucleoplasm, nucleus ATP binding, DNA binding, helicase activity, hydrolase activity, acting on acid anhydrides Human CHDH UniPathway UniProtKB {GO:0050660=GO_REF:0000002, GO:0019285=GO_REF:0000041, GO:0005743=GO_REF:0000039, GO:0008812=GO_REF:0000003} Q8NE62 Choline dehydrogenase, mitochondrial protein 20130413 {GO:0050660=IEA, GO:0019285=IEA, GO:0005743=IEA, GO:0008812=IEA} glycine betaine biosynthetic process from choline mitochondrial inner membrane choline dehydrogenase activity, flavin adenine dinucleotide binding Human UniPathway:UPA00529 CHEK1 GOC UniProtKB {GO:0005515=PMID:22939624, GO:0033261=GO_REF:0000019, GO:0005657=GO_REF:0000019, GO:0031572=PMID:20932473, GO:0005634=PMID:15311285, GO:0010569=PMID:15665856, GO:0005829=Reactome:REACT_111221, GO:0042127=GO_REF:0000019, GO:0000086=GO_REF:0000019, GO:0018107=PMID:15665856, GO:0010767=GO_REF:0000024, GO:2000615=GO_REF:0000024, GO:0000785=GO_REF:0000024, GO:0000781=PMID:15149599, GO:0005813=PMID:15311285, GO:0000794=PMID:9382850, GO:0046602=PMID:15311285, GO:0071313=GO_REF:0000019, GO:0035407=PMID:18243098, GO:0005524=GO_REF:0000037, GO:0035402=PMID:18243098, GO:0006974=PMID:20932473, GO:0006975=PMID:16963448, GO:0006260=Reactome:REACT_6769, GO:0045839=PMID:15311285, GO:0006281=PMID:19716789, GO:0004674=PMID:16963448, GO:0000075=Reactome:REACT_1538, GO:0005654=Reactome:REACT_6869, GO:0000077=PMID:16963448, GO:0090399=PMID:15149599, GO:0071260=PMID:19593445, GO:0048096=GO_REF:0000024} O14757 Serine/threonine-protein kinase Chk1 protein 20130413 {GO:0005515=IPI, GO:0033261=IEA, GO:0005657=IEA, GO:0031572=IMP, GO:0005634=IDA, GO:0010569=IDA, GO:0005829=TAS, GO:0042127=IEA, GO:0000086=IEA, GO:0018107=IDA, GO:0010767=ISS, GO:2000615=ISS, GO:0000785=ISS, GO:0000781=IDA, GO:0005813=IDA, GO:0000794=IDA, GO:0046602=IDA, GO:0071313=IEA, GO:0035407=IDA, GO:0005524=IEA, GO:0035402=IDA, GO:0006974=IMP, GO:0006975=IDA, GO:0006260=TAS, GO:0045839=IDA, GO:0006281=IMP, GO:0004674=IDA, GO:0000075=TAS, GO:0005654=TAS, GO:0000077=IDA, GO:0090399=NAS, GO:0071260=IEP, GO:0048096=ISS} DNA damage checkpoint, DNA damage induced protein phosphorylation, DNA repair, DNA replication, G2 DNA damage checkpoint, G2/M transition of mitotic cell cycle, cell cycle checkpoint, cellular response to caffeine, cellular response to mechanical stimulus, chromatin-mediated maintenance of transcription, histone H3-T11 phosphorylation, negative regulation of mitosis, peptidyl-threonine phosphorylation, regulation of S phase, regulation of cell proliferation, regulation of double-strand break repair via homologous recombination, regulation of histone H3-K9 acetylation, regulation of mitotic centrosome separation, regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage, replicative senescence, response to DNA damage stimulus centrosome, chromatin, chromosome, telomeric region, condensed nuclear chromosome, cytosol, nucleoplasm, nucleus, replication fork ATP binding, histone kinase activity (H3-T11 specific), protein binding, protein serine/threonine kinase activity Human CHEK2 BHF-UCL UniProtKB {GO:0005515=PMID:17525332, GO:0046872=GO_REF:0000037, GO:0042803=PMID:16794575, GO:0006302=PMID:18317453, GO:0046777=PMID:18644861, GO:0000086=PMID:16481012, GO:0090307=PMID:20364141, GO:0044257=PMID:11298456, GO:0010332=GO_REF:0000019, GO:0031625=PMID:22266820, GO:0016772=GO_REF:0000002, GO:0072428=PMID:11298456, GO:0000781=PMID:15149599, GO:0006355=PMID:12717439, GO:0008630=PMID:12717439, GO:0019901=PMID:16481012, GO:0042176=PMID:17101782, GO:0006915=GO_REF:0000019, GO:0005524=GO_REF:0000037, GO:0006974=PMID:16481012, GO:0006351=GO_REF:0000037, GO:0006975=PMID:11298456, GO:0042770=PMID:14744935, GO:0004672=GO_REF:0000002, GO:0004674=PMID:16794575, GO:0016605=PMID:12402044, GO:0000075=Reactome:REACT_1538, GO:0005654=Reactome:REACT_1603, GO:0000077=PMID:10617473, GO:0090399=PMID:15149599, GO:0045893=PMID:17101782, GO:0051301=GO_REF:0000037} O96017 Serine/threonine-protein kinase Chk2 protein 20110110 {GO:0005515=IPI, GO:0046872=IEA, GO:0042803=IDA, GO:0006302=IMP, GO:0046777=IDA, GO:0000086=IMP, GO:0090307=IMP, GO:0044257=IMP, GO:0010332=IEA, GO:0031625=IPI, GO:0016772=IEA, GO:0072428=IMP, GO:0000781=IDA, GO:0006355=IDA, GO:0008630=IMP, GO:0019901=IPI, GO:0042176=IMP, GO:0006915=IEA, GO:0005524=IEA, GO:0006974=IMP, GO:0006351=IEA, GO:0006975=IMP, GO:0042770=IDA, GO:0004672=IEA, GO:0004674=IDA, GO:0016605=IDA, GO:0000075=TAS, GO:0005654=TAS, GO:0000077=TAS, GO:0090399=NAS, GO:0045893=IDA, GO:0051301=IEA} DNA damage checkpoint, DNA damage induced protein phosphorylation, G2/M transition of mitotic cell cycle, apoptotic process, cell cycle checkpoint, cell division, cellular protein catabolic process, double-strand break repair, intrinsic apoptotic signaling pathway in response to DNA damage, positive regulation of transcription, DNA-dependent, protein autophosphorylation, regulation of protein catabolic process, regulation of transcription, DNA-dependent, replicative senescence, response to DNA damage stimulus, response to gamma radiation, signal transduction in response to DNA damage, signal transduction involved in intra-S DNA damage checkpoint, spindle assembly involved in mitosis, transcription, DNA-dependent PML body, chromosome, telomeric region, nucleoplasm ATP binding, metal ion binding, protein binding, protein homodimerization activity, protein kinase activity, protein kinase binding, protein serine/threonine kinase activity, transferase activity, transferring phosphorus-containing groups, ubiquitin protein ligase binding Human CHERP MGI UniProtKB {GO:0006396=GO_REF:0000002, GO:0048471=PMID:12656674, GO:0005737=PMID:10794731, GO:0008285=PMID:10794731, GO:0051209=PMID:12656674, GO:0003723=GO_REF:0000002, GO:0006874=PMID:10794731, GO:0033017=GO_REF:0000024, GO:0051533=PMID:12656674, GO:0007399=PMID:8896557, GO:0044325=PMID:21454501} Q8IWX8 Calcium homeostasis endoplasmic reticulum protein protein 20091110 {GO:0006396=IEA, GO:0048471=IDA, GO:0005737=IDA, GO:0008285=IDA, GO:0051209=IMP, GO:0003723=IEA, GO:0006874=IDA, GO:0033017=ISS, GO:0051533=IMP, GO:0007399=TAS, GO:0044325=IPI} RNA processing, cellular calcium ion homeostasis, negative regulation of cell proliferation, nervous system development, positive regulation of NFAT protein import into nucleus, release of sequestered calcium ion into cytosol cytoplasm, perinuclear region of cytoplasm, sarcoplasmic reticulum membrane RNA binding, ion channel binding Human CHFR UniProtKB UniProtKB {GO:0000209=PMID:19182791, GO:0005515=PMID:19182791, GO:0006511=GO_REF:0000019, GO:0004842=PMID:19182791, GO:0007093=PMID:19182791, GO:0005634=PMID:18172500, GO:0007067=GO_REF:0000037, GO:0000166=PMID:18172500, GO:0016605=PMID:15467728, GO:0019941=PMID:19182791, GO:0008270=GO_REF:0000002, GO:0000278=GO_REF:0000019, GO:0051301=GO_REF:0000037} Q96EP1 E3 ubiquitin-protein ligase CHFR protein 20090814 {GO:0000209=IDA, GO:0005515=IPI, GO:0006511=IEA, GO:0004842=IDA, GO:0007093=IMP, GO:0005634=IDA, GO:0007067=IEA, GO:0000166=IDA, GO:0016605=IDA, GO:0019941=IDA, GO:0008270=IEA, GO:0000278=IEA, GO:0051301=IEA} cell division, mitosis, mitotic cell cycle, mitotic cell cycle checkpoint, modification-dependent protein catabolic process, protein polyubiquitination, ubiquitin-dependent protein catabolic process PML body, nucleus nucleotide binding, protein binding, ubiquitin-protein ligase activity, zinc ion binding Human CHGA PINC UniProtKB {GO:0008217=PMID:8406464, GO:0005576=GO_REF:0000039, GO:0030141=GO_REF:0000002, GO:0030658=GO_REF:0000039} P10645 Chromogranin-A protein 20030904 {GO:0008217=TAS, GO:0005576=IEA, GO:0030141=IEA, GO:0030658=IEA} regulation of blood pressure extracellular region, secretory granule, transport vesicle membrane Human CHGB IntAct UniProtKB {GO:0005515=PMID:20195357, GO:0005179=PMID:3608978, GO:0005576=GO_REF:0000039, GO:0030141=GO_REF:0000019} P05060 Secretogranin-1 protein 20130415 {GO:0005515=IPI, GO:0005179=TAS, GO:0005576=IEA, GO:0030141=IEA} extracellular region, secretory granule hormone activity, protein binding Human UniProtKB:Q15796 CHI3L1 UniProtKB UniProtKB {GO:0051897=PMID:21385870, GO:0006032=GO_REF:0000002, GO:0010800=GO_REF:0000024, GO:0007250=GO_REF:0000024, GO:0030324=PMID:18403759, GO:0005975=GO_REF:0000002, GO:0005783=GO_REF:0000024, GO:0051216=PMID:8245017, GO:0005578=PMID:8245017, GO:0045766=PMID:21385870, GO:0004553=GO_REF:0000002, GO:0009612=PMID:20650887, GO:0008061=PMID:12775711, GO:0005737=GO_REF:0000024, GO:0006954=PMID:16234240, GO:0071356=GO_REF:0000024, GO:0070741=PMID:21478032, GO:0034612=PMID:16234240, GO:0070374=PMID:21385870, GO:0070555=PMID:16234240, GO:0004568=PMID:9492324, GO:0072606=GO_REF:0000024, GO:0005201=PMID:8245017} P36222 Chitinase-3-like protein 1 protein 20111221 {GO:0051897=IMP, GO:0006032=IEA, GO:0010800=ISS, GO:0007250=ISS, GO:0030324=IMP, GO:0005975=IEA, GO:0005783=ISS, GO:0051216=NAS, GO:0005578=NAS, GO:0045766=IMP, GO:0004553=IEA, GO:0009612=IEP, GO:0008061=IDA, GO:0005737=ISS, GO:0006954=IEP, GO:0071356=ISS, GO:0070741=IEP, GO:0034612=IEP, GO:0070374=IMP, GO:0070555=IEP, GO:0004568=IDA, GO:0072606=ISS, GO:0005201=NAS} activation of NF-kappaB-inducing kinase activity, carbohydrate metabolic process, cartilage development, cellular response to tumor necrosis factor, chitin catabolic process, inflammatory response, interleukin-8 secretion, lung development, positive regulation of ERK1 and ERK2 cascade, positive regulation of angiogenesis, positive regulation of peptidyl-threonine phosphorylation, positive regulation of protein kinase B signaling cascade, response to interleukin-1, response to interleukin-6, response to mechanical stimulus, response to tumor necrosis factor cytoplasm, endoplasmic reticulum, proteinaceous extracellular matrix chitin binding, chitinase activity, extracellular matrix structural constituent, hydrolase activity, hydrolyzing O-glycosyl compounds Human CHI3L2 PINC UniProtKB {GO:0008061=PMID:22742450, GO:0006032=GO_REF:0000002, GO:0005975=GO_REF:0000002, GO:0005615=PMID:8702629, GO:0004553=GO_REF:0000002, GO:0004568=PMID:22742450} Q15782 Chitinase-3-like protein 2 protein 20030904 {GO:0008061=IDA, GO:0006032=IEA, GO:0005975=IEA, GO:0005615=TAS, GO:0004553=IEA, GO:0004568=IDA} carbohydrate metabolic process, chitin catabolic process extracellular space chitin binding, chitinase activity, hydrolase activity, hydrolyzing O-glycosyl compounds Human CHIC1 UniProtKB UniProtKB {GO:0005886=GO_REF:0000039, GO:0016023=GO_REF:0000039} Q5VXU3 Cysteine-rich hydrophobic domain 1 protein protein 20130413 {GO:0005886=IEA, GO:0016023=IEA} cytoplasmic membrane-bounded vesicle, plasma membrane Human UniProtKB-SubCell:SL-0088 CHIC2 IntAct UniProtKB {GO:0005515=PMID:19060904, GO:0003674=GO_REF:0000015, GO:0008150=GO_REF:0000015, GO:0005886=GO_REF:0000039, GO:0005798=GO_REF:0000019, GO:0005575=GO_REF:0000015} Q9UKJ5 Cysteine-rich hydrophobic domain 2 protein protein 20130415 {GO:0005515=IPI, GO:0003674=ND, GO:0008150=ND, GO:0005886=IEA, GO:0005798=IEA, GO:0005575=ND} biological_process Golgi-associated vesicle, cellular_component, plasma membrane molecular_function, protein binding Human UniProtKB:Q9H8W4 CHID1 UniProtKB UniProtKB {GO:0006032=GO_REF:0000002, GO:0005975=GO_REF:0000002, GO:0045087=GO_REF:0000037, GO:0005576=GO_REF:0000039, GO:0003824=GO_REF:0000002, GO:0005764=GO_REF:0000039, GO:0004568=GO_REF:0000002} Q9BWS9 Chitinase domain-containing protein 1 protein 20130413 {GO:0006032=IEA, GO:0005975=IEA, GO:0045087=IEA, GO:0005576=IEA, GO:0003824=IEA, GO:0005764=IEA, GO:0004568=IEA} carbohydrate metabolic process, chitin catabolic process, innate immune response extracellular region, lysosome catalytic activity, chitinase activity Human UniProtKB-SubCell:SL-0158 CHKA GOC UniProtKB {GO:0006629=PMID:10363580, GO:0033265=GO_REF:0000019, GO:0004305=PMID:19915674, GO:0006646=Reactome:REACT_120919, GO:0004104=GO_REF:0000019, GO:0004103=PMID:19915674, GO:0044281=Reactome:REACT_111217, GO:0005524=GO_REF:0000019, GO:0019695=GO_REF:0000019, GO:0042803=GO_REF:0000019, GO:0005829=Reactome:REACT_121281, GO:0007165=PMID:10363580, GO:0016301=GO_REF:0000002, GO:0008144=PMID:19915674, GO:0006869=PMID:10363580, GO:0004871=PMID:10363580, GO:0006657=PMID:19915674, GO:0006644=Reactome:REACT_120870, GO:0046474=Reactome:REACT_121401, GO:0006656=Reactome:REACT_121238} P35790 Choline kinase alpha protein 20130413 {GO:0006629=TAS, GO:0033265=IEA, GO:0004305=IDA, GO:0006646=TAS, GO:0004104=IEA, GO:0004103=IDA, GO:0044281=TAS, GO:0005524=IEA, GO:0019695=IEA, GO:0042803=IEA, GO:0005829=TAS, GO:0007165=TAS, GO:0016301=IEA, GO:0008144=IDA, GO:0006869=TAS, GO:0004871=TAS, GO:0006657=IDA, GO:0006644=TAS, GO:0046474=TAS, GO:0006656=TAS} CDP-choline pathway, choline metabolic process, glycerophospholipid biosynthetic process, lipid metabolic process, lipid transport, phosphatidylcholine biosynthetic process, phosphatidylethanolamine biosynthetic process, phospholipid metabolic process, signal transduction, small molecule metabolic process cytosol ATP binding, choline binding, choline kinase activity, cholinesterase activity, drug binding, ethanolamine kinase activity, kinase activity, protein homodimerization activity, signal transducer activity Human CHKB HPA UniProtKB {GO:0004305=PMID:19915674, GO:0006646=Reactome:REACT_120919, GO:0005737=GO_REF:0000052, GO:0004103=PMID:19915674, GO:0044281=Reactome:REACT_111217, GO:0006657=PMID:19915674, GO:0006644=Reactome:REACT_120870, GO:0005524=GO_REF:0000037, GO:0046474=Reactome:REACT_121401, GO:0006656=Reactome:REACT_121238, GO:0005829=Reactome:REACT_121281} Q9Y259 Choline/ethanolamine kinase protein 20090616 {GO:0004305=IDA, GO:0006646=TAS, GO:0005737=IDA, GO:0004103=IDA, GO:0044281=TAS, GO:0006657=IDA, GO:0006644=TAS, GO:0005524=IEA, GO:0046474=TAS, GO:0006656=TAS, GO:0005829=TAS} CDP-choline pathway, glycerophospholipid biosynthetic process, phosphatidylcholine biosynthetic process, phosphatidylethanolamine biosynthetic process, phospholipid metabolic process, small molecule metabolic process cytoplasm, cytosol ATP binding, choline kinase activity, ethanolamine kinase activity Human CHL1 Reactome UniProtKB {GO:0008344=GO_REF:0000019, GO:0005886=GO_REF:0000039, GO:0005578=GO_REF:0000039, GO:0045177=GO_REF:0000019, GO:0002020=GO_REF:0000019, GO:0030425=GO_REF:0000019, GO:0007165=PMID:9799093, GO:0043524=GO_REF:0000019, GO:0050890=GO_REF:0000019, GO:0007411=Reactome:REACT_18266, GO:0016021=GO_REF:0000037, GO:0001764=GO_REF:0000019, GO:0007155=GO_REF:0000037} O00533 Neural cell adhesion molecule L1-like protein protein 20091012 {GO:0008344=IEA, GO:0005886=IEA, GO:0005578=IEA, GO:0045177=IEA, GO:0002020=IEA, GO:0030425=IEA, GO:0007165=TAS, GO:0043524=IEA, GO:0050890=IEA, GO:0007411=TAS, GO:0016021=IEA, GO:0001764=IEA, GO:0007155=IEA} adult locomotory behavior, axon guidance, cell adhesion, cognition, negative regulation of neuron apoptotic process, neuron migration, signal transduction apical part of cell, dendrite, integral to membrane, plasma membrane, proteinaceous extracellular matrix protease binding Human CHM PINC UniProtKB {GO:0018344=PMID:8380507, GO:0001568=GO_REF:0000019, GO:0005968=GO_REF:0000002, GO:0004663=GO_REF:0000002, GO:0007601=GO_REF:0000037, GO:0006886=GO_REF:0000002, GO:0050896=GO_REF:0000037, GO:0005096=GO_REF:0000037} P24386 Rab proteins geranylgeranyltransferase component A 1 protein 20031119 {GO:0018344=TAS, GO:0001568=IEA, GO:0005968=IEA, GO:0004663=IEA, GO:0007601=IEA, GO:0006886=IEA, GO:0050896=IEA, GO:0005096=IEA} blood vessel development, intracellular protein transport, protein geranylgeranylation, response to stimulus, visual perception Rab-protein geranylgeranyltransferase complex GTPase activator activity, Rab geranylgeranyltransferase activity Human CHML PINC UniProtKB {GO:0005968=GO_REF:0000002, GO:0004663=GO_REF:0000002, GO:0007601=PMID:1301160, GO:0006886=GO_REF:0000002, GO:0005096=GO_REF:0000037} P26374 Rab proteins geranylgeranyltransferase component A 2 protein 20030904 {GO:0005968=IEA, GO:0004663=IEA, GO:0007601=TAS, GO:0006886=IEA, GO:0005096=IEA} intracellular protein transport, visual perception Rab-protein geranylgeranyltransferase complex GTPase activator activity, Rab geranylgeranyltransferase activity Human CHMP1A IntAct UniProtKB {GO:0005515=PMID:21988832, GO:0007076=PMID:11559747, GO:0000794=PMID:11559747, GO:0005815=PMID:11559748, GO:0019904=PMID:17928862, GO:0016458=PMID:11559747, GO:0015031=GO_REF:0000037, GO:0006351=GO_REF:0000037, GO:0016363=PMID:11559747, GO:0045749=PMID:11559747, GO:0012505=PMID:11559748, GO:0045014=PMID:9837962, GO:0000910=PMID:19129479, GO:0008270=PMID:8863740, GO:0016192=PMID:11559748, GO:0045892=PMID:11559747, GO:0008237=PMID:8863740, GO:0010008=GO_REF:0000039, GO:0005769=PMID:11559748} Q9HD42 Charged multivesicular body protein 1a protein 20130415 {GO:0005515=IPI, GO:0007076=IDA, GO:0000794=IDA, GO:0005815=IDA, GO:0019904=IPI, GO:0016458=IDA, GO:0015031=IEA, GO:0006351=IEA, GO:0016363=IDA, GO:0045749=IMP, GO:0012505=IDA, GO:0045014=IDA, GO:0000910=IMP, GO:0008270=TAS, GO:0016192=IDA, GO:0045892=IDA, GO:0008237=TAS, GO:0010008=IEA, GO:0005769=IDA} cytokinesis, gene silencing, mitotic chromosome condensation, negative regulation of S phase of mitotic cell cycle, negative regulation of transcription by glucose, negative regulation of transcription, DNA-dependent, protein transport, transcription, DNA-dependent, vesicle-mediated transport condensed nuclear chromosome, early endosome, endomembrane system, endosome membrane, microtubule organizing center, nuclear matrix metallopeptidase activity, protein binding, protein domain specific binding, zinc ion binding Human UniProtKB:O95630 CHMP1B IntAct UniProtKB {GO:0005515=PMID:21988832, GO:0000910=PMID:19129479, GO:0007049=GO_REF:0000037, GO:0019904=PMID:17928862, GO:0031902=GO_REF:0000039, GO:0015031=GO_REF:0000037, GO:0005829=GO_REF:0000039} Q7LBR1 Charged multivesicular body protein 1b protein 20130415 {GO:0005515=IPI, GO:0000910=IMP, GO:0007049=IEA, GO:0019904=IPI, GO:0031902=IEA, GO:0015031=IEA, GO:0005829=IEA} cell cycle, cytokinesis, protein transport cytosol, late endosome membrane protein binding, protein domain specific binding Human UniProtKB:O95630 CHMP2A Reactome UniProtKB {GO:0005515=PMID:19525971, GO:0016197=Reactome:REACT_27258, GO:0019904=PMID:17928862, GO:0031902=GO_REF:0000039, GO:0015031=GO_REF:0000037, GO:0016044=Reactome:REACT_11123, GO:0005829=Reactome:REACT_27290} O43633 Charged multivesicular body protein 2a protein 20130301 {GO:0005515=IPI, GO:0016197=TAS, GO:0019904=IPI, GO:0031902=IEA, GO:0015031=IEA, GO:0016044=TAS, GO:0005829=TAS} cellular membrane organization, endosomal transport, protein transport cytosol, late endosome membrane protein binding, protein domain specific binding Human CHMP2B HPA UniProtKB {GO:0005739=GO_REF:0000052, GO:0005622=GO_REF:0000054, GO:0008219=GO_REF:0000037, GO:0005737=GO_REF:0000052, GO:0016197=Reactome:REACT_27258, GO:0019904=PMID:17928862, GO:0031902=GO_REF:0000039, GO:0005634=GO_REF:0000052, GO:0015031=GO_REF:0000037, GO:0016044=Reactome:REACT_11123, GO:0005829=Reactome:REACT_27290} Q9UQN3 Charged multivesicular body protein 2b protein 20101115 {GO:0005739=IDA, GO:0005622=IDA, GO:0008219=IEA, GO:0005737=IDA, GO:0016197=TAS, GO:0019904=IPI, GO:0031902=IEA, GO:0005634=IDA, GO:0015031=IEA, GO:0016044=TAS, GO:0005829=TAS} cell death, cellular membrane organization, endosomal transport, protein transport cytoplasm, cytosol, intracellular, late endosome membrane, mitochondrion, nucleus protein domain specific binding Human CHMP3 IntAct UniProtKB {GO:0005515=PMID:19615732, GO:0007049=GO_REF:0000037, GO:0016197=Reactome:REACT_27258, GO:0031902=GO_REF:0000039, GO:0006915=GO_REF:0000037, GO:0015031=GO_REF:0000037, GO:0016044=Reactome:REACT_11123, GO:0005829=Reactome:REACT_27290, GO:0051301=GO_REF:0000037} Q9Y3E7 Charged multivesicular body protein 3 protein 20130415 {GO:0005515=IPI, GO:0007049=IEA, GO:0016197=TAS, GO:0031902=IEA, GO:0006915=IEA, GO:0015031=IEA, GO:0016044=TAS, GO:0005829=TAS, GO:0051301=IEA} apoptotic process, cell cycle, cell division, cellular membrane organization, endosomal transport, protein transport cytosol, late endosome membrane protein binding Human UniProtKB:O95630 CHMP4A Reactome UniProtKB {GO:0016197=Reactome:REACT_27258, GO:0031902=GO_REF:0000039, GO:0015031=GO_REF:0000037, GO:0016044=Reactome:REACT_11123, GO:0030659=GO_REF:0000039, GO:0005829=Reactome:REACT_27290, GO:0008289=GO_REF:0000037} Q9BY43 Charged multivesicular body protein 4a protein 20130301 {GO:0016197=TAS, GO:0031902=IEA, GO:0015031=IEA, GO:0016044=TAS, GO:0030659=IEA, GO:0005829=TAS, GO:0008289=IEA} cellular membrane organization, endosomal transport, protein transport cytoplasmic vesicle membrane, cytosol, late endosome membrane lipid binding Human CHMP4B Reactome UniProtKB {GO:0005515=PMID:20208530, GO:0016197=Reactome:REACT_27258, GO:0031902=GO_REF:0000039, GO:0015031=GO_REF:0000037, GO:0016044=Reactome:REACT_11123, GO:0005829=Reactome:REACT_27290} Q9H444 Charged multivesicular body protein 4b protein 20130301 {GO:0005515=IPI, GO:0016197=TAS, GO:0031902=IEA, GO:0015031=IEA, GO:0016044=TAS, GO:0005829=TAS} cellular membrane organization, endosomal transport, protein transport cytosol, late endosome membrane protein binding Human CHMP4C Reactome UniProtKB {GO:0016197=Reactome:REACT_27258, GO:0031902=GO_REF:0000039, GO:0015031=GO_REF:0000037, GO:0016044=Reactome:REACT_11123, GO:0005829=Reactome:REACT_27290} Q96CF2 Charged multivesicular body protein 4c protein 20130301 {GO:0016197=TAS, GO:0031902=IEA, GO:0015031=IEA, GO:0016044=TAS, GO:0005829=TAS} cellular membrane organization, endosomal transport, protein transport cytosol, late endosome membrane Human CHMP5 IntAct UniProtKB {GO:0005515=PMID:21988832, GO:0001919=GO_REF:0000019, GO:0016197=Reactome:REACT_27258, GO:0008333=GO_REF:0000019, GO:0005634=GO_REF:0000019, GO:0015031=GO_REF:0000037, GO:0007040=GO_REF:0000019, GO:0016044=Reactome:REACT_11123, GO:0010008=GO_REF:0000039, GO:0005829=Reactome:REACT_27184} Q9NZZ3 Charged multivesicular body protein 5 protein 20130415 {GO:0005515=IPI, GO:0001919=IEA, GO:0016197=TAS, GO:0008333=IEA, GO:0005634=IEA, GO:0015031=IEA, GO:0007040=IEA, GO:0016044=TAS, GO:0010008=IEA, GO:0005829=TAS} cellular membrane organization, endosomal transport, endosome to lysosome transport, lysosome organization, protein transport, regulation of receptor recycling cytosol, endosome membrane, nucleus protein binding Human UniProtKB:O95630 CHMP6 Reactome UniProtKB {GO:0047485=PMID:18606141, GO:0016197=Reactome:REACT_27258, GO:0031902=GO_REF:0000039, GO:0015031=GO_REF:0000037, GO:0016044=Reactome:REACT_11123, GO:0005829=Reactome:REACT_27290, GO:0012505=GO_REF:0000039} Q96FZ7 Charged multivesicular body protein 6 protein 20100729 {GO:0047485=IPI, GO:0016197=TAS, GO:0031902=IEA, GO:0015031=IEA, GO:0016044=TAS, GO:0005829=TAS, GO:0012505=IEA} cellular membrane organization, endosomal transport, protein transport cytosol, endomembrane system, late endosome membrane protein N-terminus binding Human CHMP7 HPA UniProtKB {GO:0000815=PMID:16856878, GO:0005737=GO_REF:0000052, GO:0045324=PMID:16856878, GO:0016197=Reactome:REACT_27258, GO:0008565=PMID:16856878, GO:0005634=GO_REF:0000052, GO:0016044=Reactome:REACT_11123, GO:0005829=Reactome:REACT_27290} Q8WUX9 Charged multivesicular body protein 7 protein 20110516 {GO:0000815=IDA, GO:0005737=IDA, GO:0045324=IMP, GO:0016197=TAS, GO:0008565=IMP, GO:0005634=IDA, GO:0016044=TAS, GO:0005829=TAS} cellular membrane organization, endosomal transport, late endosome to vacuole transport ESCRT III complex, cytoplasm, cytosol, nucleus protein transporter activity Human CHN1 Reactome UniProtKB {GO:0051056=Reactome:REACT_11051, GO:0048013=GO_REF:0000024, GO:0007264=Reactome:REACT_11044, GO:0046872=GO_REF:0000037, GO:0005829=Reactome:REACT_9982, GO:0005622=GO_REF:0000002, GO:0035556=GO_REF:0000002, GO:0007165=GO_REF:0000002, GO:0008045=GO_REF:0000024, GO:0032314=GO_REF:0000019, GO:0046875=GO_REF:0000019, GO:0005070=PMID:8336731, GO:0050770=GO_REF:0000024, GO:0005096=GO_REF:0000037} P15882 N-chimaerin protein 20130301 {GO:0051056=TAS, GO:0048013=ISS, GO:0007264=TAS, GO:0046872=IEA, GO:0005829=TAS, GO:0005622=IEA, GO:0035556=IEA, GO:0007165=IEA, GO:0008045=ISS, GO:0032314=IEA, GO:0046875=IEA, GO:0005070=TAS, GO:0050770=ISS, GO:0005096=IEA} ephrin receptor signaling pathway, intracellular signal transduction, motor neuron axon guidance, regulation of Rac GTPase activity, regulation of axonogenesis, regulation of small GTPase mediated signal transduction, signal transduction, small GTPase mediated signal transduction cytosol, intracellular GTPase activator activity, SH3/SH2 adaptor activity, ephrin receptor binding, metal ion binding Human CHN2 GOC UniProtKB {GO:0043547=PMID:7614486, GO:0035556=GO_REF:0000002, GO:0005622=GO_REF:0000002, GO:0051056=Reactome:REACT_11051, GO:0007165=GO_REF:0000002, GO:0016020=GO_REF:0000039, GO:0007264=Reactome:REACT_11044, GO:0005070=PMID:8175705, GO:0046872=GO_REF:0000037, GO:0005829=Reactome:REACT_9982, GO:0005096=GO_REF:0000037} P52757 Beta-chimaerin protein 20130413 {GO:0043547=TAS, GO:0035556=IEA, GO:0005622=IEA, GO:0051056=TAS, GO:0007165=IEA, GO:0016020=IEA, GO:0007264=TAS, GO:0005070=TAS, GO:0046872=IEA, GO:0005829=TAS, GO:0005096=IEA} intracellular signal transduction, positive regulation of GTPase activity, regulation of small GTPase mediated signal transduction, signal transduction, small GTPase mediated signal transduction cytosol, intracellular, membrane GTPase activator activity, SH3/SH2 adaptor activity, metal ion binding Human CHODL HGNC UniProtKB {GO:0048471=PMID:12079284, GO:0005737=PMID:22042635, GO:0007517=PMID:12079284, GO:0005540=PMID:12079284, GO:0030246=GO_REF:0000002, GO:0016021=GO_REF:0000037} Q9H9P2 Chondrolectin protein 20051208 {GO:0048471=IDA, GO:0005737=IDA, GO:0007517=NAS, GO:0005540=IDA, GO:0030246=IEA, GO:0016021=IEA} muscle organ development cytoplasm, integral to membrane, perinuclear region of cytoplasm carbohydrate binding, hyaluronic acid binding Human CHORDC1 IntAct UniProtKB {GO:0005515=PMID:19875381, GO:0080134=GO_REF:0000024, GO:0061077=GO_REF:0000024, GO:0051879=PMID:19875381, GO:0006950=GO_REF:0000037, GO:0008270=GO_REF:0000019, GO:0005575=GO_REF:0000015, GO:2000299=GO_REF:0000019, GO:0010824=GO_REF:0000019} Q9UHD1 Cysteine and histidine-rich domain-containing protein 1 protein 20130415 {GO:0005515=IPI, GO:0080134=ISS, GO:0061077=ISS, GO:0051879=IPI, GO:0006950=IEA, GO:0008270=IEA, GO:0005575=ND, GO:2000299=IEA, GO:0010824=IEA} chaperone-mediated protein folding, negative regulation of Rho-dependent protein serine/threonine kinase activity, regulation of centrosome duplication, regulation of response to stress, response to stress cellular_component Hsp90 protein binding, protein binding, zinc ion binding Human UniProtKB:P07900 CHP2 UniProtKB UniProtKB {GO:0005515=PMID:21392185, GO:0005737=PMID:21392185, GO:0008284=PMID:21392185, GO:0005886=PMID:21392185, GO:0045944=PMID:18815128, GO:0005509=PMID:21392185, GO:0010922=PMID:18815128, GO:0071277=PMID:18815128, GO:0042307=PMID:18815128, GO:0005634=PMID:21392185, GO:0070886=PMID:18815128, GO:0015031=GO_REF:0000037} O43745 Calcineurin B homologous protein 2 protein 20120626 {GO:0005515=IPI, GO:0005737=IDA, GO:0008284=IDA, GO:0005886=IDA, GO:0045944=IDA, GO:0005509=IDA, GO:0010922=IDA, GO:0071277=IDA, GO:0042307=IDA, GO:0005634=IDA, GO:0070886=IDA, GO:0015031=IEA} cellular response to calcium ion, positive regulation of calcineurin-NFAT signaling cascade, positive regulation of cell proliferation, positive regulation of phosphatase activity, positive regulation of protein import into nucleus, positive regulation of transcription from RNA polymerase II promoter, protein transport cytoplasm, nucleus, plasma membrane calcium ion binding, protein binding Human CHPF Reactome UniProtKB {GO:0030206=Reactome:REACT_120989, GO:0000139=Reactome:REACT_121192, GO:0016758=GO_REF:0000002, GO:0005975=Reactome:REACT_474, GO:0032580=GO_REF:0000039, GO:0044281=Reactome:REACT_111217, GO:0016021=GO_REF:0000037, GO:0030204=Reactome:REACT_121206, GO:0030203=Reactome:REACT_121315, GO:0050510=GO_REF:0000003, GO:0047238=GO_REF:0000003, GO:0046872=GO_REF:0000037} Q8IZ52 Chondroitin sulfate synthase 2 protein 20130301 {GO:0030206=TAS, GO:0000139=TAS, GO:0016758=IEA, GO:0005975=TAS, GO:0032580=IEA, GO:0044281=TAS, GO:0016021=IEA, GO:0030204=TAS, GO:0030203=TAS, GO:0050510=IEA, GO:0047238=IEA, GO:0046872=IEA} carbohydrate metabolic process, chondroitin sulfate biosynthetic process, chondroitin sulfate metabolic process, glycosaminoglycan metabolic process, small molecule metabolic process Golgi cisterna membrane, Golgi membrane, integral to membrane N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity, glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity, metal ion binding, transferase activity, transferring hexosyl groups Human CHPT1 Reactome UniProtKB {GO:0006629=PMID:10893425, GO:0006663=PMID:10893425, GO:0044281=Reactome:REACT_111217, GO:0008654=GO_REF:0000002, GO:0001558=PMID:10893425, GO:0046872=GO_REF:0000037, GO:0043231=PMID:10893425, GO:0019992=PMID:10893425, GO:0016780=GO_REF:0000002, GO:0000139=Reactome:REACT_120834, GO:0016020=PMID:10893425, GO:0016021=GO_REF:0000037, GO:0004142=Reactome:REACT_120834, GO:0006644=Reactome:REACT_120870, GO:0006657=PMID:10893425, GO:0046474=Reactome:REACT_121401, GO:0006656=Reactome:REACT_121238} Q8WUD6 Cholinephosphotransferase 1 protein 20110824 {GO:0006629=TAS, GO:0006663=IDA, GO:0044281=TAS, GO:0008654=IEA, GO:0001558=NAS, GO:0046872=IEA, GO:0043231=NAS, GO:0019992=NAS, GO:0016780=IEA, GO:0000139=TAS, GO:0016020=NAS, GO:0016021=IEA, GO:0004142=TAS, GO:0006644=TAS, GO:0006657=NAS, GO:0046474=TAS, GO:0006656=TAS} CDP-choline pathway, glycerophospholipid biosynthetic process, lipid metabolic process, phosphatidylcholine biosynthetic process, phospholipid biosynthetic process, phospholipid metabolic process, platelet activating factor biosynthetic process, regulation of cell growth, small molecule metabolic process Golgi membrane, integral to membrane, intracellular membrane-bounded organelle, membrane diacylglycerol binding, diacylglycerol cholinephosphotransferase activity, metal ion binding, phosphotransferase activity, for other substituted phosphate groups Human CHRAC1 UniProtKB UniProtKB {GO:0043565=GO_REF:0000002, GO:0005622=GO_REF:0000002, GO:0008623=PMID:10880450, GO:0008622=PMID:10880450, GO:0046982=GO_REF:0000002, GO:0003887=PMID:10880450, GO:0006338=PMID:10880450, GO:0003677=PMID:10880450} Q9NRG0 Chromatin accessibility complex protein 1 protein 20030110 {GO:0043565=IEA, GO:0005622=IEA, GO:0008623=NAS, GO:0008622=NAS, GO:0046982=IEA, GO:0003887=NAS, GO:0006338=NAS, GO:0003677=NAS} chromatin remodeling CHRAC, epsilon DNA polymerase complex, intracellular DNA binding, DNA-directed DNA polymerase activity, protein heterodimerization activity, sequence-specific DNA binding Human CHRD BHF-UCL UniProtKB {GO:0005515=PMID:21988832, GO:0030336=PMID:16449796, GO:0001707=GO_REF:0000019, GO:0033504=PMID:11790302, GO:0021919=PMID:11472837, GO:0002053=PMID:18533030, GO:0005615=PMID:16449796, GO:0001649=GO_REF:0000019, GO:0001702=GO_REF:0000019, GO:0045785=PMID:16449796, GO:0030514=PMID:11472837, GO:0001501=PMID:9782094, GO:0045668=PMID:18533030, GO:0019955=PMID:16449796, GO:0030900=GO_REF:0000019, GO:0008201=GO_REF:0000019, GO:0045545=GO_REF:0000019} Q9H2X0 Chordin protein 20120508 {GO:0005515=IPI, GO:0030336=IDA, GO:0001707=IEA, GO:0033504=TAS, GO:0021919=IMP, GO:0002053=IMP, GO:0005615=NAS, GO:0001649=IEA, GO:0001702=IEA, GO:0045785=IDA, GO:0030514=IMP, GO:0001501=TAS, GO:0045668=IMP, GO:0019955=NAS, GO:0030900=IEA, GO:0008201=IEA, GO:0045545=IEA} BMP signaling pathway involved in spinal cord dorsal/ventral patterning, floor plate development, forebrain development, gastrulation with mouth forming second, mesoderm formation, negative regulation of BMP signaling pathway, negative regulation of cell migration, negative regulation of osteoblast differentiation, osteoblast differentiation, positive regulation of cell adhesion, positive regulation of mesenchymal cell proliferation, skeletal system development extracellular space cytokine binding, heparin binding, protein binding, syndecan binding Human CHRDL1 Reactome UniProtKB {GO:0048749=PMID:22284829, GO:0001503=GO_REF:0000037, GO:0001654=PMID:22284829, GO:0005576=Reactome:REACT_12026, GO:0030509=Reactome:REACT_12034, GO:0030154=GO_REF:0000037, GO:0007399=GO_REF:0000037} Q9BU40 Chordin-like protein 1 protein 20130301 {GO:0048749=IMP, GO:0001503=IEA, GO:0001654=IMP, GO:0005576=TAS, GO:0030509=TAS, GO:0030154=IEA, GO:0007399=IEA} BMP signaling pathway, cell differentiation, compound eye development, eye development, nervous system development, ossification extracellular region Human CHRDL2 HPA UniProtKB {GO:0005739=GO_REF:0000052, GO:0001503=GO_REF:0000037, GO:0051216=GO_REF:0000037, GO:0005576=GO_REF:0000039, GO:0030154=GO_REF:0000037} Q6WN34 Chordin-like protein 2 protein 20090616 {GO:0005739=IDA, GO:0001503=IEA, GO:0051216=IEA, GO:0005576=IEA, GO:0030154=IEA} cartilage development, cell differentiation, ossification extracellular region, mitochondrion Human CHRFAM7A UniProtKB UniProtKB {GO:0005230=GO_REF:0000002, GO:0045211=GO_REF:0000002, GO:0016021=GO_REF:0000037} Q494W8 CHRNA7-FAM7A fusion protein protein 20130413 {GO:0005230=IEA, GO:0045211=IEA, GO:0016021=IEA} integral to membrane, postsynaptic membrane extracellular ligand-gated ion channel activity Human UniProtKB-KW:KW-0812 CHRM1 ENSEMBL UniProtKB {GO:0008284=PMID:2739737, GO:0030054=GO_REF:0000037, GO:0005886=Reactome:REACT_22436, GO:0008283=PMID:1905013, GO:0043269=GO_REF:0000002, GO:0007205=PMID:9603968, GO:0032279=GO_REF:0000019, GO:0040012=GO_REF:0000019, GO:0043270=PMID:14657398, GO:0045211=GO_REF:0000039, GO:0008144=GO_REF:0000019, GO:0043679=GO_REF:0000019, GO:0060079=GO_REF:0000002, GO:0014069=GO_REF:0000019, GO:0007274=GO_REF:0000019, GO:1900274=GO_REF:0000002, GO:0007213=PMID:8139539, GO:0016907=GO_REF:0000019, GO:0007399=PMID:2739737, GO:0007165=PMID:9614217, GO:0016020=PMID:7925360, GO:0007186=PMID:7925360, GO:0005887=GO_REF:0000002, GO:0004435=PMID:9614217, GO:0007207=PMID:8139539, GO:0006464=PMID:1411529} Q96RH1 Muscarinic acetylcholine receptor M1 protein 20130413 {GO:0008284=TAS, GO:0030054=IEA, GO:0005886=TAS, GO:0008283=TAS, GO:0043269=IEA, GO:0007205=TAS, GO:0032279=IEA, GO:0040012=IEA, GO:0043270=IGI, GO:0045211=IEA, GO:0008144=IEA, GO:0043679=IEA, GO:0060079=IEA, GO:0014069=IEA, GO:0007274=IEA, GO:1900274=IEA, GO:0007213=TAS, GO:0016907=IEA, GO:0007399=TAS, GO:0007165=TAS, GO:0016020=TAS, GO:0007186=TAS, GO:0005887=IEA, GO:0004435=TAS, GO:0007207=TAS, GO:0006464=TAS} G-protein coupled acetylcholine receptor signaling pathway, G-protein coupled receptor signaling pathway, cell proliferation, cellular protein modification process, nervous system development, neuromuscular synaptic transmission, phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway, positive regulation of cell proliferation, positive regulation of ion transport, protein kinase C-activating G-protein coupled receptor signaling pathway, regulation of excitatory postsynaptic membrane potential, regulation of ion transport, regulation of locomotion, regulation of phospholipase C activity, signal transduction asymmetric synapse, axon terminus, cell junction, integral to plasma membrane, membrane, plasma membrane, postsynaptic density, postsynaptic membrane G-protein coupled acetylcholine receptor activity, drug binding, phosphatidylinositol phospholipase C activity Human Ensembl:ENSRNOP00000024785 CHRM2 LIFEdb UniProtKB {GO:0030054=GO_REF:0000037, GO:0005886=GO_REF:0000054, GO:0008016=GO_REF:0000002, GO:0009615=PMID:16548883, GO:0043269=GO_REF:0000002, GO:0016907=GO_REF:0000019, GO:0007399=PMID:2739737, GO:0007186=PMID:9603968, GO:0005887=GO_REF:0000002, GO:0007187=PMID:10895079, GO:0045211=GO_REF:0000039, GO:0007207=PMID:2739737, GO:0030815=GO_REF:0000002, GO:0007188=PMID:8139539} P08172 Muscarinic acetylcholine receptor M2 protein 20100607 {GO:0030054=IEA, GO:0005886=IDA, GO:0008016=IEA, GO:0009615=IEP, GO:0043269=IEA, GO:0016907=IEA, GO:0007399=TAS, GO:0007186=TAS, GO:0005887=IEA, GO:0007187=TAS, GO:0045211=IEA, GO:0007207=TAS, GO:0030815=IEA, GO:0007188=TAS} G-protein coupled receptor signaling pathway, G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger, adenylate cyclase-modulating G-protein coupled receptor signaling pathway, negative regulation of cAMP metabolic process, nervous system development, phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway, regulation of heart contraction, regulation of ion transport, response to virus cell junction, integral to plasma membrane, plasma membrane, postsynaptic membrane G-protein coupled acetylcholine receptor activity Human CHRM3 Reactome UniProtKB {GO:0030054=GO_REF:0000037, GO:0005886=Reactome:REACT_22436, GO:0008283=PMID:8063729, GO:0044281=Reactome:REACT_111217, GO:0030425=GO_REF:0000019, GO:0043269=GO_REF:0000002, GO:0032279=GO_REF:0000019, GO:0006939=GO_REF:0000019, GO:0016323=GO_REF:0000039, GO:0045987=GO_REF:0000019, GO:0008144=GO_REF:0000019, GO:0045211=GO_REF:0000039, GO:0042166=GO_REF:0000019, GO:0043679=GO_REF:0000019, GO:0004872=PMID:10940357, GO:0007586=GO_REF:0000019, GO:1900274=GO_REF:0000002, GO:0016907=GO_REF:0000019, GO:0007399=PMID:2739737, GO:0007165=PMID:10940357, GO:0006112=Reactome:REACT_1505, GO:0050796=Reactome:REACT_18325, GO:0007186=PMID:9603968, GO:0004435=PMID:1905013, GO:0005887=GO_REF:0000002, GO:0003056=GO_REF:0000019, GO:0006464=PMID:10051746} P20309 Muscarinic acetylcholine receptor M3 protein 20130111 {GO:0030054=IEA, GO:0005886=TAS, GO:0008283=TAS, GO:0044281=TAS, GO:0030425=IEA, GO:0043269=IEA, GO:0032279=IEA, GO:0006939=IEA, GO:0016323=IEA, GO:0045987=IEA, GO:0008144=IEA, GO:0045211=IEA, GO:0042166=IEA, GO:0043679=IEA, GO:0004872=TAS, GO:0007586=IEA, GO:1900274=IEA, GO:0016907=IEA, GO:0007399=TAS, GO:0007165=TAS, GO:0006112=TAS, GO:0050796=TAS, GO:0007186=TAS, GO:0004435=TAS, GO:0005887=IEA, GO:0003056=IEA, GO:0006464=TAS} G-protein coupled receptor signaling pathway, cell proliferation, cellular protein modification process, digestion, energy reserve metabolic process, nervous system development, positive regulation of smooth muscle contraction, regulation of insulin secretion, regulation of ion transport, regulation of phospholipase C activity, regulation of vascular smooth muscle contraction, signal transduction, small molecule metabolic process, smooth muscle contraction asymmetric synapse, axon terminus, basolateral plasma membrane, cell junction, dendrite, integral to plasma membrane, plasma membrane, postsynaptic membrane G-protein coupled acetylcholine receptor activity, acetylcholine binding, drug binding, phosphatidylinositol phospholipase C activity, receptor activity Human CHRM4 Reactome UniProtKB {GO:0010033=GO_REF:0000002, GO:0030054=GO_REF:0000037, GO:0005886=Reactome:REACT_22289, GO:0008283=PMID:2739737, GO:0007197=GO_REF:0000019, GO:0014056=GO_REF:0000002, GO:0007213=PMID:3443095, GO:0016907=GO_REF:0000019, GO:0040012=GO_REF:0000002, GO:0007165=PMID:9603968, GO:0005887=GO_REF:0000002, GO:0045211=GO_REF:0000039, GO:0007166=PMID:2739737} P08173 Muscarinic acetylcholine receptor M4 protein 20090210 {GO:0010033=IEA, GO:0030054=IEA, GO:0005886=TAS, GO:0008283=TAS, GO:0007197=IEA, GO:0014056=IEA, GO:0007213=TAS, GO:0016907=IEA, GO:0040012=IEA, GO:0007165=TAS, GO:0005887=IEA, GO:0045211=IEA, GO:0007166=TAS} G-protein coupled acetylcholine receptor signaling pathway, adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway, cell proliferation, cell surface receptor signaling pathway, regulation of acetylcholine secretion, regulation of locomotion, response to organic substance, signal transduction cell junction, integral to plasma membrane, plasma membrane, postsynaptic membrane G-protein coupled acetylcholine receptor activity Human CHRM5 Reactome UniProtKB {GO:0030054=GO_REF:0000037, GO:0005886=Reactome:REACT_22436, GO:0008283=PMID:8063729, GO:0015872=GO_REF:0000019, GO:0007197=PMID:8663391, GO:1900274=GO_REF:0000002, GO:0007213=PMID:3272174, GO:0016907=GO_REF:0000019, GO:0060304=GO_REF:0000019, GO:0043269=GO_REF:0000002, GO:0005887=GO_REF:0000002, GO:0004435=PMID:1905013, GO:0045211=GO_REF:0000039, GO:0030815=GO_REF:0000002} P08912 Muscarinic acetylcholine receptor M5 protein 20130111 {GO:0030054=IEA, GO:0005886=TAS, GO:0008283=TAS, GO:0015872=IEA, GO:0007197=TAS, GO:1900274=IEA, GO:0007213=TAS, GO:0016907=IEA, GO:0060304=IEA, GO:0043269=IEA, GO:0005887=IEA, GO:0004435=TAS, GO:0045211=IEA, GO:0030815=IEA} G-protein coupled acetylcholine receptor signaling pathway, adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway, cell proliferation, dopamine transport, negative regulation of cAMP metabolic process, regulation of ion transport, regulation of phosphatidylinositol dephosphorylation, regulation of phospholipase C activity cell junction, integral to plasma membrane, plasma membrane, postsynaptic membrane G-protein coupled acetylcholine receptor activity, phosphatidylinositol phospholipase C activity Human CHRNA1 BHF-UCL UniProtKB {GO:0048630=PMID:18252226, GO:0005230=GO_REF:0000002, GO:0031594=PMID:8872460, GO:0030054=GO_REF:0000037, GO:0005886=PMID:8872460, GO:0007268=Reactome:REACT_13685, GO:0019228=PMID:8872460, GO:0046716=PMID:8872460, GO:0050905=PMID:9546329, GO:0050881=PMID:18252226, GO:0007528=PMID:9221765, GO:0045211=PMID:18252226, GO:0015464=PMID:8872460, GO:0042391=PMID:8872460, GO:0006810=PMID:7619526, GO:0042166=PMID:8872460, GO:0009986=PMID:12928480, GO:0007274=PMID:9221765, GO:0005892=PMID:8872460, GO:0007165=PMID:7619526, GO:0003009=PMID:8872460, GO:0016021=GO_REF:0000038, GO:0070050=PMID:8872460, GO:0005216=PMID:6688857, GO:0004889=PMID:8872460} P02708 Acetylcholine receptor subunit alpha protein 20080923 {GO:0048630=IMP, GO:0005230=IEA, GO:0031594=ISS, GO:0030054=IEA, GO:0005886=ISS, GO:0007268=TAS, GO:0019228=IMP, GO:0046716=IMP, GO:0050905=IMP, GO:0050881=IMP, GO:0007528=IMP, GO:0045211=NAS, GO:0015464=ISS, GO:0042391=IMP, GO:0006810=TAS, GO:0042166=ISS, GO:0009986=IDA, GO:0007274=IMP, GO:0005892=ISS, GO:0007165=TAS, GO:0003009=IMP, GO:0016021=IEA, GO:0070050=IMP, GO:0005216=TAS, GO:0004889=ISS} muscle cell homeostasis, musculoskeletal movement, neuromuscular junction development, neuromuscular process, neuromuscular synaptic transmission, neuron homeostasis, regulation of action potential in neuron, regulation of membrane potential, signal transduction, skeletal muscle contraction, skeletal muscle tissue growth, synaptic transmission, transport acetylcholine-gated channel complex, cell junction, cell surface, integral to membrane, neuromuscular junction, plasma membrane, postsynaptic membrane acetylcholine binding, acetylcholine receptor activity, acetylcholine-activated cation-selective channel activity, extracellular ligand-gated ion channel activity, ion channel activity contributes_to Human UniProtKB:P04756 CHRNA2 Reactome UniProtKB {GO:0007165=PMID:8906617, GO:0030054=GO_REF:0000037, GO:0005886=Reactome:REACT_22409, GO:0015464=PMID:8906617, GO:0045211=GO_REF:0000039, GO:0007268=Reactome:REACT_13685, GO:0016021=PMID:8906617, GO:0005892=PMID:8906617, GO:0004889=PMID:8906617, GO:0006811=PMID:8906617, GO:0071944=GO_REF:0000019} Q15822 Neuronal acetylcholine receptor subunit alpha-2 protein 20100429 {GO:0007165=IDA, GO:0030054=IEA, GO:0005886=TAS, GO:0015464=IDA, GO:0045211=IEA, GO:0007268=TAS, GO:0016021=NAS, GO:0005892=IDA, GO:0004889=IDA, GO:0006811=NAS, GO:0071944=IEA} ion transport, signal transduction, synaptic transmission acetylcholine-gated channel complex, cell junction, cell periphery, integral to membrane, plasma membrane, postsynaptic membrane acetylcholine receptor activity, acetylcholine-activated cation-selective channel activity Human CHRNA3 Reactome UniProtKB {GO:0030054=GO_REF:0000037, GO:0005886=Reactome:REACT_22438, GO:0007268=Reactome:REACT_13685, GO:0006940=GO_REF:0000024, GO:0060084=PMID:11450844, GO:0014056=GO_REF:0000024, GO:0030425=GO_REF:0000024, GO:0007171=GO_REF:0000024, GO:0015464=PMID:8906617, GO:0045211=GO_REF:0000039, GO:0042391=GO_REF:0000024, GO:0042166=PMID:8906617, GO:0043025=GO_REF:0000024, GO:0007626=GO_REF:0000024, GO:0006811=PMID:8906617, GO:0015276=PMID:20438829, GO:0060079=GO_REF:0000024, GO:0014069=GO_REF:0000024, GO:0005892=PMID:8906617, GO:0007271=GO_REF:0000024, GO:0007399=PMID:11450844, GO:0035095=PMID:18227835, GO:0048814=GO_REF:0000024, GO:0007165=PMID:8906617, GO:0016021=PMID:8906617, GO:0004889=PMID:8906617} P32297 Neuronal acetylcholine receptor subunit alpha-3 protein 20100429 {GO:0030054=IEA, GO:0005886=TAS, GO:0007268=TAS, GO:0006940=ISS, GO:0060084=IMP, GO:0014056=ISS, GO:0030425=ISS, GO:0007171=ISS, GO:0015464=IDA, GO:0045211=IEA, GO:0042391=ISS, GO:0042166=IC, GO:0043025=ISS, GO:0007626=ISS, GO:0006811=NAS, GO:0015276=TAS, GO:0060079=ISS, GO:0014069=ISS, GO:0005892=IDA, GO:0007271=ISS, GO:0007399=IMP, GO:0035095=IMP, GO:0048814=ISS, GO:0007165=IDA, GO:0016021=NAS, GO:0004889=IDA} activation of transmembrane receptor protein tyrosine kinase activity, behavioral response to nicotine, ion transport, locomotory behavior, nervous system development, regulation of acetylcholine secretion, regulation of dendrite morphogenesis, regulation of excitatory postsynaptic membrane potential, regulation of membrane potential, regulation of smooth muscle contraction, signal transduction, synaptic transmission, synaptic transmission involved in micturition, synaptic transmission, cholinergic acetylcholine-gated channel complex, cell junction, dendrite, integral to membrane, neuronal cell body, plasma membrane, postsynaptic density, postsynaptic membrane acetylcholine binding, acetylcholine receptor activity, acetylcholine-activated cation-selective channel activity, ligand-gated ion channel activity Human CHRNA4 Reactome UniProtKB {GO:0051899=GO_REF:0000024, GO:0030054=GO_REF:0000037, GO:0005886=Reactome:REACT_22438, GO:0007268=Reactome:REACT_13685, GO:0030425=GO_REF:0000024, GO:0014059=GO_REF:0000024, GO:0015464=PMID:8906617, GO:0045211=GO_REF:0000039, GO:0042391=GO_REF:0000024, GO:0042166=PMID:8906617, GO:0043025=GO_REF:0000024, GO:0007626=GO_REF:0000019, GO:0006816=GO_REF:0000024, GO:0006979=PMID:16332175, GO:0006811=PMID:8906617, GO:0015276=PMID:20438829, GO:0001666=PMID:12189247, GO:0005892=PMID:8906617, GO:0007271=GO_REF:0000024, GO:0019233=GO_REF:0000024, GO:0035095=PMID:17955458, GO:0042113=GO_REF:0000024, GO:0007165=PMID:8906617, GO:0060080=GO_REF:0000024, GO:0006281=PMID:16332175, GO:0050890=PMID:14623738, GO:0016020=GO_REF:0000024, GO:0050877=PMID:17613539, GO:0016021=PMID:8906617, GO:0001508=GO_REF:0000024, GO:0004889=PMID:20438829, GO:0009897=GO_REF:0000024, GO:0035094=PMID:12189247} P43681 Neuronal acetylcholine receptor subunit alpha-4 protein 20100429 {GO:0051899=ISS, GO:0030054=IEA, GO:0005886=TAS, GO:0007268=TAS, GO:0030425=ISS, GO:0014059=ISS, GO:0015464=IDA, GO:0045211=IEA, GO:0042391=ISS, GO:0042166=IC, GO:0043025=ISS, GO:0007626=IEA, GO:0006816=ISS, GO:0006979=IMP, GO:0006811=NAS, GO:0015276=TAS, GO:0001666=IDA, GO:0005892=IDA, GO:0007271=ISS, GO:0019233=ISS, GO:0035095=IMP, GO:0042113=ISS, GO:0007165=IDA, GO:0060080=ISS, GO:0006281=IMP, GO:0050890=IMP, GO:0016020=ISS, GO:0050877=IMP, GO:0016021=NAS, GO:0001508=ISS, GO:0004889=TAS, GO:0009897=ISS, GO:0035094=IDA} B cell activation, DNA repair, behavioral response to nicotine, calcium ion transport, cognition, ion transport, locomotory behavior, membrane depolarization, neurological system process, regulation of action potential, regulation of dopamine secretion, regulation of inhibitory postsynaptic membrane potential, regulation of membrane potential, response to hypoxia, response to nicotine, response to oxidative stress, sensory perception of pain, signal transduction, synaptic transmission, synaptic transmission, cholinergic acetylcholine-gated channel complex, cell junction, dendrite, external side of plasma membrane, integral to membrane, membrane, neuronal cell body, plasma membrane, postsynaptic membrane acetylcholine binding, acetylcholine receptor activity, acetylcholine-activated cation-selective channel activity, ligand-gated ion channel activity Human CHRNA5 Reactome UniProtKB {GO:0030054=GO_REF:0000037, GO:0005886=Reactome:REACT_22409, GO:0007268=Reactome:REACT_13685, GO:0005892=PMID:1542648, GO:0035095=PMID:18227835, GO:0007165=PMID:9009220, GO:0045211=GO_REF:0000039, GO:0015464=PMID:1542648, GO:0006810=PMID:1542648, GO:0016021=GO_REF:0000038, GO:0004889=PMID:1542648, GO:0006811=GO_REF:0000002, GO:0015276=PMID:20438829} P30532 Neuronal acetylcholine receptor subunit alpha-5 protein 20100429 {GO:0030054=IEA, GO:0005886=TAS, GO:0007268=TAS, GO:0005892=IC, GO:0035095=IMP, GO:0007165=NAS, GO:0045211=IEA, GO:0015464=IDA, GO:0006810=NAS, GO:0016021=IEA, GO:0004889=NAS, GO:0006811=IEA, GO:0015276=TAS} behavioral response to nicotine, ion transport, signal transduction, synaptic transmission, transport acetylcholine-gated channel complex, cell junction, integral to membrane, plasma membrane, postsynaptic membrane acetylcholine receptor activity, acetylcholine-activated cation-selective channel activity, ligand-gated ion channel activity Human CHRNA7 Reactome UniProtKB {GO:0005230=GO_REF:0000002, GO:0008284=PMID:16280133, GO:0030054=GO_REF:0000037, GO:0005886=Reactome:REACT_22243, GO:0007268=Reactome:REACT_13685, GO:0042221=PMID:18387948, GO:0042803=PMID:8145738, GO:0000187=PMID:10771023, GO:0001540=PMID:10681545, GO:0045211=GO_REF:0000039, GO:0015464=PMID:8906617, GO:0042166=PMID:8145738, GO:0006816=PMID:8145738, GO:0007613=PMID:10681545, GO:0006811=PMID:8906617, GO:0001666=PMID:12189247, GO:0006874=PMID:16280133, GO:0032720=PMID:12508119, GO:0045766=PMID:16280133, GO:0005892=PMID:8906617, GO:0007165=PMID:8906617, GO:0050890=PMID:10681545, GO:0015643=PMID:12508119, GO:0016021=PMID:8906617, GO:0004889=PMID:12508119, GO:0017081=PMID:8145738, GO:0035094=PMID:8145738} P36544 Neuronal acetylcholine receptor subunit alpha-7 protein 20100429 {GO:0005230=IEA, GO:0008284=IMP, GO:0030054=IEA, GO:0005886=TAS, GO:0007268=TAS, GO:0042221=IDA, GO:0042803=IDA, GO:0000187=IDA, GO:0001540=IPI, GO:0045211=IEA, GO:0015464=IDA, GO:0042166=IDA, GO:0006816=IDA, GO:0007613=NAS, GO:0006811=NAS, GO:0001666=IDA, GO:0006874=IMP, GO:0032720=IDA, GO:0045766=IMP, GO:0005892=IDA, GO:0007165=IDA, GO:0050890=NAS, GO:0015643=IDA, GO:0016021=NAS, GO:0004889=IDA, GO:0017081=IDA, GO:0035094=IDA} activation of MAPK activity, calcium ion transport, cellular calcium ion homeostasis, cognition, ion transport, memory, negative regulation of tumor necrosis factor production, positive regulation of angiogenesis, positive regulation of cell proliferation, response to chemical stimulus, response to hypoxia, response to nicotine, signal transduction, synaptic transmission acetylcholine-gated channel complex, cell junction, integral to membrane, plasma membrane, postsynaptic membrane acetylcholine binding, acetylcholine receptor activity, acetylcholine-activated cation-selective channel activity, beta-amyloid binding, chloride channel regulator activity, extracellular ligand-gated ion channel activity, protein homodimerization activity, toxic substance binding Human CHRNA9 Reactome UniProtKB {GO:0005262=GO_REF:0000037, GO:0042472=GO_REF:0000019, GO:0030054=GO_REF:0000037, GO:0005886=Reactome:REACT_22243, GO:0045211=GO_REF:0000039, GO:0050910=GO_REF:0000019, GO:0007268=Reactome:REACT_13685, GO:0007204=PMID:18420419, GO:0005892=GO_REF:0000019, GO:0004889=GO_REF:0000019} Q9UGM1 Neuronal acetylcholine receptor subunit alpha-9 protein 20130301 {GO:0005262=IEA, GO:0042472=IEA, GO:0030054=IEA, GO:0005886=TAS, GO:0045211=IEA, GO:0050910=IEA, GO:0007268=TAS, GO:0007204=IGI, GO:0005892=IEA, GO:0004889=IEA} detection of mechanical stimulus involved in sensory perception of sound, elevation of cytosolic calcium ion concentration, inner ear morphogenesis, synaptic transmission acetylcholine-gated channel complex, cell junction, plasma membrane, postsynaptic membrane acetylcholine-activated cation-selective channel activity, calcium channel activity Human CHRNB1 UniProtKB UniProtKB {GO:0030054=GO_REF:0000037, GO:0005886=GO_REF:0000038, GO:0045202=PMID:8872460, GO:0007274=PMID:8651643, GO:0005892=PMID:8872460, GO:0007271=PMID:8872460, GO:0035095=PMID:16874522, GO:0048747=PMID:8651643, GO:0007165=PMID:8872460, GO:0006936=PMID:8651643, GO:0005887=PMID:8872460, GO:0015464=PMID:8872460, GO:0045211=GO_REF:0000039, GO:0042391=GO_REF:0000024, GO:0042166=GO_REF:0000024, GO:0050877=PMID:11104662, GO:0001941=PMID:8651643, GO:0016021=GO_REF:0000038, GO:0004889=GO_REF:0000024, GO:0006812=PMID:8872460, GO:0015267=PMID:8872460, GO:0015276=GO_REF:0000024} P11230 Acetylcholine receptor subunit beta protein 20080623 {GO:0030054=IEA, GO:0005886=IEA, GO:0045202=IMP, GO:0007274=IMP, GO:0005892=IMP, GO:0007271=IMP, GO:0035095=IMP, GO:0048747=IMP, GO:0007165=IMP, GO:0006936=IMP, GO:0005887=NAS, GO:0015464=IMP, GO:0045211=IEA, GO:0042391=ISS, GO:0042166=ISS, GO:0050877=IMP, GO:0001941=IMP, GO:0016021=IEA, GO:0004889=ISS, GO:0006812=IMP, GO:0015267=IMP, GO:0015276=ISS} behavioral response to nicotine, cation transport, muscle contraction, muscle fiber development, neurological system process, neuromuscular synaptic transmission, postsynaptic membrane organization, regulation of membrane potential, signal transduction, synaptic transmission, cholinergic acetylcholine-gated channel complex, cell junction, integral to membrane, integral to plasma membrane, plasma membrane, postsynaptic membrane, synapse acetylcholine binding, acetylcholine receptor activity, acetylcholine-activated cation-selective channel activity, channel activity, ligand-gated ion channel activity contributes_to Human UniProtKB:P09690 CHRNB2 Reactome UniProtKB {GO:0030054=GO_REF:0000037, GO:0007605=GO_REF:0000024, GO:0042220=GO_REF:0000024, GO:0060084=GO_REF:0000024, GO:0045759=GO_REF:0000024, GO:0006939=GO_REF:0000024, GO:0045211=GO_REF:0000039, GO:0015464=PMID:8906617, GO:0042166=PMID:8906617, GO:0007613=PMID:15964197, GO:0001661=GO_REF:0000019, GO:0007612=PMID:15964197, GO:0015276=PMID:20438829, GO:0008306=GO_REF:0000024, GO:0051963=GO_REF:0000024, GO:0007271=GO_REF:0000024, GO:0005892=PMID:8906617, GO:0042113=GO_REF:0000024, GO:0032226=GO_REF:0000019, GO:0032225=GO_REF:0000024, GO:0008542=PMID:15964197, GO:0035176=GO_REF:0000024, GO:0050877=PMID:17900292, GO:0021631=GO_REF:0000024, GO:0009897=GO_REF:0000024, GO:0004889=PMID:20438829, GO:0051899=GO_REF:0000024, GO:0005886=Reactome:REACT_22438, GO:0030890=GO_REF:0000024, GO:0045471=GO_REF:0000024, GO:0007268=Reactome:REACT_13685, GO:0045188=GO_REF:0000019, GO:0014059=GO_REF:0000024, GO:0042053=GO_REF:0000024, GO:0021771=GO_REF:0000024, GO:0006816=GO_REF:0000024, GO:0007626=GO_REF:0000024, GO:0006811=PMID:8906617, GO:0001666=PMID:12189247, GO:0021952=GO_REF:0000024, GO:0021562=GO_REF:0000024, GO:0019233=GO_REF:0000024, GO:0035095=PMID:17559419, GO:0048814=GO_REF:0000024, GO:0007165=PMID:8906617, GO:0050890=PMID:17559419, GO:0042320=GO_REF:0000024, GO:0016021=PMID:8906617, GO:0007601=GO_REF:0000024, GO:0035094=PMID:12189247, GO:0033603=GO_REF:0000024} P17787 Neuronal acetylcholine receptor subunit beta-2 protein 20100429 {GO:0030054=IEA, GO:0007605=ISS, GO:0042220=ISS, GO:0060084=ISS, GO:0045759=ISS, GO:0006939=ISS, GO:0045211=IEA, GO:0015464=IDA, GO:0042166=IC, GO:0007613=IMP, GO:0001661=IEA, GO:0007612=IMP, GO:0015276=TAS, GO:0008306=ISS, GO:0051963=ISS, GO:0007271=ISS, GO:0005892=IDA, GO:0042113=ISS, GO:0032226=IEA, GO:0032225=ISS, GO:0008542=IMP, GO:0035176=ISS, GO:0050877=IMP, GO:0021631=ISS, GO:0009897=ISS, GO:0004889=TAS, GO:0051899=ISS, GO:0005886=TAS, GO:0030890=ISS, GO:0045471=ISS, GO:0007268=TAS, GO:0045188=IEA, GO:0014059=ISS, GO:0042053=ISS, GO:0021771=ISS, GO:0006816=ISS, GO:0007626=ISS, GO:0006811=NAS, GO:0001666=IDA, GO:0021952=ISS, GO:0021562=ISS, GO:0019233=ISS, GO:0035095=IMP, GO:0048814=ISS, GO:0007165=IDA, GO:0050890=IMP, GO:0042320=ISS, GO:0016021=NAS, GO:0007601=ISS, GO:0035094=IDA, GO:0033603=ISS} B cell activation, associative learning, behavioral response to nicotine, calcium ion transport, central nervous system projection neuron axonogenesis, cognition, conditioned taste aversion, ion transport, lateral geniculate nucleus development, learning, locomotory behavior, membrane depolarization, memory, negative regulation of action potential, neurological system process, optic nerve morphogenesis, positive regulation of B cell proliferation, positive regulation of dopamine secretion, positive regulation of synaptic transmission, dopaminergic, regulation of circadian sleep/wake cycle, REM sleep, regulation of circadian sleep/wake cycle, non-REM sleep, regulation of dendrite morphogenesis, regulation of dopamine metabolic process, regulation of dopamine secretion, regulation of synapse assembly, regulation of synaptic transmission, dopaminergic, response to cocaine, response to ethanol, response to hypoxia, response to nicotine, sensory perception of pain, sensory perception of sound, signal transduction, smooth muscle contraction, social behavior, synaptic transmission, synaptic transmission involved in micturition, synaptic transmission, cholinergic, vestibulocochlear nerve development, visual learning, visual perception acetylcholine-gated channel complex, cell junction, external side of plasma membrane, integral to membrane, plasma membrane, postsynaptic membrane acetylcholine binding, acetylcholine receptor activity, acetylcholine-activated cation-selective channel activity, ligand-gated ion channel activity Human CHRNB4 Reactome UniProtKB {GO:0005230=GO_REF:0000002, GO:0030054=GO_REF:0000037, GO:0005886=Reactome:REACT_22438, GO:0007268=Reactome:REACT_13685, GO:0046928=PMID:11742001, GO:0006940=GO_REF:0000019, GO:0060084=PMID:11450844, GO:0007271=PMID:1330682, GO:0005892=PMID:11742001, GO:0006939=GO_REF:0000019, GO:0035095=GO_REF:0000019, GO:0007165=PMID:8906617, GO:0005887=PMID:11742001, GO:0015464=PMID:8906617, GO:0045211=GO_REF:0000039, GO:0007626=GO_REF:0000019, GO:0016021=PMID:8906617, GO:0001508=GO_REF:0000019, GO:0004889=PMID:11742001, GO:0015276=PMID:20438829, GO:0006811=PMID:8906617} P30926 Neuronal acetylcholine receptor subunit beta-4 protein 20100429 {GO:0005230=IEA, GO:0030054=IEA, GO:0005886=TAS, GO:0007268=TAS, GO:0046928=NAS, GO:0006940=IEA, GO:0060084=IMP, GO:0007271=TAS, GO:0005892=TAS, GO:0006939=IEA, GO:0035095=IEA, GO:0007165=IDA, GO:0005887=IC, GO:0015464=IDA, GO:0045211=IEA, GO:0007626=IEA, GO:0016021=NAS, GO:0001508=IEA, GO:0004889=TAS, GO:0015276=TAS, GO:0006811=TAS} behavioral response to nicotine, ion transport, locomotory behavior, regulation of action potential, regulation of neurotransmitter secretion, regulation of smooth muscle contraction, signal transduction, smooth muscle contraction, synaptic transmission, synaptic transmission involved in micturition, synaptic transmission, cholinergic acetylcholine-gated channel complex, cell junction, integral to membrane, integral to plasma membrane, plasma membrane, postsynaptic membrane acetylcholine receptor activity, acetylcholine-activated cation-selective channel activity, extracellular ligand-gated ion channel activity, ligand-gated ion channel activity Human CHRND BHF-UCL UniProtKB {GO:0048630=PMID:18252226, GO:0005230=GO_REF:0000002, GO:0030054=GO_REF:0000037, GO:0005886=Reactome:REACT_22438, GO:0007268=Reactome:REACT_13685, GO:0005892=GO_REF:0000019, GO:0050905=PMID:18252226, GO:0007165=PMID:8872460, GO:0006936=PMID:8872460, GO:0050881=PMID:18252226, GO:0045211=PMID:18252226, GO:0042391=GO_REF:0000019, GO:0042166=GO_REF:0000019, GO:0006810=PMID:8872460, GO:0016021=GO_REF:0000038, GO:0004889=GO_REF:0000019, GO:0006811=GO_REF:0000002} Q07001 Acetylcholine receptor subunit delta protein 20080923 {GO:0048630=IMP, GO:0005230=IEA, GO:0030054=IEA, GO:0005886=TAS, GO:0007268=TAS, GO:0005892=IEA, GO:0050905=NAS, GO:0007165=TAS, GO:0006936=TAS, GO:0050881=IMP, GO:0045211=NAS, GO:0042391=IEA, GO:0042166=IEA, GO:0006810=TAS, GO:0016021=IEA, GO:0004889=IEA, GO:0006811=IEA} ion transport, muscle contraction, musculoskeletal movement, neuromuscular process, regulation of membrane potential, signal transduction, skeletal muscle tissue growth, synaptic transmission, transport acetylcholine-gated channel complex, cell junction, integral to membrane, plasma membrane, postsynaptic membrane acetylcholine binding, acetylcholine-activated cation-selective channel activity, extracellular ligand-gated ion channel activity Human CHRNE GOC UniProtKB {GO:0030054=GO_REF:0000037, GO:0005886=Reactome:REACT_22438, GO:0008324=PMID:8872460, GO:0007268=Reactome:REACT_13685, GO:0005892=PMID:7531341, GO:0007271=PMID:8872460, GO:0007165=PMID:8872460, GO:0006936=PMID:8872460, GO:0005887=PMID:8872460, GO:0045211=GO_REF:0000039, GO:0015464=PMID:8872460, GO:0042391=GO_REF:0000019, GO:0006810=PMID:8872460, GO:0006812=PMID:8872460, GO:0004889=GO_REF:0000019} Q04844 Acetylcholine receptor subunit epsilon protein 20130413 {GO:0030054=IEA, GO:0005886=TAS, GO:0008324=TAS, GO:0007268=TAS, GO:0005892=TAS, GO:0007271=TAS, GO:0007165=TAS, GO:0006936=TAS, GO:0005887=TAS, GO:0045211=IEA, GO:0015464=TAS, GO:0042391=IEA, GO:0006810=TAS, GO:0006812=TAS, GO:0004889=IEA} cation transport, muscle contraction, regulation of membrane potential, signal transduction, synaptic transmission, synaptic transmission, cholinergic, transport acetylcholine-gated channel complex, cell junction, integral to plasma membrane, plasma membrane, postsynaptic membrane acetylcholine receptor activity, acetylcholine-activated cation-selective channel activity, cation transmembrane transporter activity Human CHRNG Reactome UniProtKB {GO:0030054=GO_REF:0000037, GO:0005886=Reactome:REACT_22438, GO:0007268=Reactome:REACT_13685, GO:0005892=GO_REF:0000019, GO:0007165=PMID:3967651, GO:0006936=PMID:8040310, GO:0005887=PMID:3967651, GO:0045211=GO_REF:0000039, GO:0015464=PMID:3967651, GO:0042391=GO_REF:0000019, GO:0006810=PMID:3967651, GO:0016021=GO_REF:0000038, GO:0004889=GO_REF:0000019, GO:0015267=PMID:3967651} P07510 Acetylcholine receptor subunit gamma protein 20130301 {GO:0030054=IEA, GO:0005886=TAS, GO:0007268=TAS, GO:0005892=IEA, GO:0007165=TAS, GO:0006936=TAS, GO:0005887=TAS, GO:0045211=IEA, GO:0015464=TAS, GO:0042391=IEA, GO:0006810=TAS, GO:0016021=IEA, GO:0004889=IEA, GO:0015267=TAS} muscle contraction, regulation of membrane potential, signal transduction, synaptic transmission, transport acetylcholine-gated channel complex, cell junction, integral to membrane, integral to plasma membrane, plasma membrane, postsynaptic membrane acetylcholine receptor activity, acetylcholine-activated cation-selective channel activity, channel activity Human CHST1 Reactome UniProtKB {GO:0006790=PMID:10330415, GO:0005976=PMID:9405439, GO:0005975=Reactome:REACT_474, GO:0044281=Reactome:REACT_111217, GO:0042339=Reactome:REACT_121288, GO:0006954=GO_REF:0000037, GO:0045130=PMID:9405439, GO:0000139=Reactome:REACT_121317, GO:0018146=Reactome:REACT_121120, GO:0008146=PMID:10330415, GO:0016021=PMID:9405439, GO:0006012=PMID:10330415, GO:0030203=Reactome:REACT_121315} O43916 Carbohydrate sulfotransferase 1 protein 20130301 {GO:0006790=IDA, GO:0005976=TAS, GO:0005975=TAS, GO:0044281=TAS, GO:0042339=TAS, GO:0006954=IEA, GO:0045130=IDA, GO:0000139=TAS, GO:0018146=TAS, GO:0008146=IDA, GO:0016021=NAS, GO:0006012=IDA, GO:0030203=TAS} carbohydrate metabolic process, galactose metabolic process, glycosaminoglycan metabolic process, inflammatory response, keratan sulfate biosynthetic process, keratan sulfate metabolic process, polysaccharide metabolic process, small molecule metabolic process, sulfur compound metabolic process Golgi membrane, integral to membrane keratan sulfotransferase activity, sulfotransferase activity Human CHST10 PINC UniProtKB {GO:0016051=GO_REF:0000002, GO:0005794=PMID:9478973, GO:0016232=GO_REF:0000019, GO:0016020=PMID:9478973, GO:0000139=GO_REF:0000039, GO:0007616=GO_REF:0000019, GO:0008146=PMID:9478973, GO:0007612=GO_REF:0000019, GO:0016021=GO_REF:0000037, GO:0007155=PMID:9478973} O43529 Carbohydrate sulfotransferase 10 protein 20030904 {GO:0016051=IEA, GO:0005794=TAS, GO:0016232=IEA, GO:0016020=TAS, GO:0000139=IEA, GO:0007616=IEA, GO:0008146=TAS, GO:0007612=IEA, GO:0016021=IEA, GO:0007155=TAS} carbohydrate biosynthetic process, cell adhesion, learning, long-term memory Golgi apparatus, Golgi membrane, integral to membrane, membrane HNK-1 sulfotransferase activity, sulfotransferase activity Human CHST12 Reactome UniProtKB {GO:0005975=Reactome:REACT_474, GO:0044281=Reactome:REACT_111217, GO:0050656=PMID:10781601, GO:0016051=GO_REF:0000002, GO:0047756=PMID:10781601, GO:0030208=PMID:10781601, GO:0030206=Reactome:REACT_120989, GO:0030173=PMID:10781601, GO:0000139=Reactome:REACT_121270, GO:0008146=GO_REF:0000002, GO:0016021=GO_REF:0000002, GO:0030204=Reactome:REACT_121206, GO:0030203=Reactome:REACT_121315} Q9NRB3 Carbohydrate sulfotransferase 12 protein 20130301 {GO:0005975=TAS, GO:0044281=TAS, GO:0050656=NAS, GO:0016051=IEA, GO:0047756=IDA, GO:0030208=IDA, GO:0030206=TAS, GO:0030173=NAS, GO:0000139=TAS, GO:0008146=IEA, GO:0016021=IEA, GO:0030204=TAS, GO:0030203=TAS} carbohydrate biosynthetic process, carbohydrate metabolic process, chondroitin sulfate biosynthetic process, chondroitin sulfate metabolic process, dermatan sulfate biosynthetic process, glycosaminoglycan metabolic process, small molecule metabolic process Golgi membrane, integral to Golgi membrane, integral to membrane 3'-phosphoadenosine 5'-phosphosulfate binding, chondroitin 4-sulfotransferase activity, sulfotransferase activity Human CHST14 Reactome UniProtKB {GO:0030208=Reactome:REACT_120800, GO:0016051=GO_REF:0000002, GO:0000139=Reactome:REACT_120903, GO:0005975=Reactome:REACT_474, GO:0042301=PMID:11470797, GO:0008146=GO_REF:0000002, GO:0001537=PMID:11470797, GO:0044281=Reactome:REACT_111217, GO:0016021=PMID:11470797, GO:0030204=Reactome:REACT_121206, GO:0030203=Reactome:REACT_121315, GO:0050655=PMID:11470797} Q8NCH0 Carbohydrate sulfotransferase 14 protein 20130301 {GO:0030208=TAS, GO:0016051=IEA, GO:0000139=TAS, GO:0005975=TAS, GO:0042301=NAS, GO:0008146=IEA, GO:0001537=IDA, GO:0044281=TAS, GO:0016021=NAS, GO:0030204=TAS, GO:0030203=TAS, GO:0050655=IDA} carbohydrate biosynthetic process, carbohydrate metabolic process, chondroitin sulfate metabolic process, dermatan sulfate biosynthetic process, dermatan sulfate proteoglycan metabolic process, glycosaminoglycan metabolic process, small molecule metabolic process Golgi membrane, integral to membrane N-acetylgalactosamine 4-O-sulfotransferase activity, phosphate ion binding, sulfotransferase activity Human CHST15 Reactome UniProtKB {GO:0030206=Reactome:REACT_120989, GO:0000139=Reactome:REACT_120940, GO:0005975=Reactome:REACT_474, GO:0044281=Reactome:REACT_111217, GO:0019319=PMID:11572857, GO:0016021=PMID:11572857, GO:0050659=PMID:11572857, GO:0030204=Reactome:REACT_121206, GO:0050656=PMID:11572857, GO:0030203=Reactome:REACT_121315} Q7LFX5 Carbohydrate sulfotransferase 15 protein 20130301 {GO:0030206=TAS, GO:0000139=TAS, GO:0005975=TAS, GO:0044281=TAS, GO:0019319=IDA, GO:0016021=NAS, GO:0050659=IDA, GO:0030204=TAS, GO:0050656=IDA, GO:0030203=TAS} carbohydrate metabolic process, chondroitin sulfate biosynthetic process, chondroitin sulfate metabolic process, glycosaminoglycan metabolic process, hexose biosynthetic process, small molecule metabolic process Golgi membrane, integral to membrane 3'-phosphoadenosine 5'-phosphosulfate binding, N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase activity Human CHST3 Reactome UniProtKB {GO:0006790=PMID:9883891, GO:0030206=Reactome:REACT_120989, GO:0000139=Reactome:REACT_120725, GO:0005975=Reactome:REACT_474, GO:0050698=GO_REF:0000019, GO:0008146=PMID:9883891, GO:0008459=PMID:9883891, GO:0044281=Reactome:REACT_111217, GO:0016021=GO_REF:0000037, GO:0030204=Reactome:REACT_121206, GO:0043029=GO_REF:0000019, GO:0030203=Reactome:REACT_121315} Q7LGC8 Carbohydrate sulfotransferase 3 protein 20130301 {GO:0006790=IDA, GO:0030206=TAS, GO:0000139=TAS, GO:0005975=TAS, GO:0050698=IEA, GO:0008146=TAS, GO:0008459=IDA, GO:0044281=TAS, GO:0016021=IEA, GO:0030204=TAS, GO:0043029=IEA, GO:0030203=TAS} T cell homeostasis, carbohydrate metabolic process, chondroitin sulfate biosynthetic process, chondroitin sulfate metabolic process, glycosaminoglycan metabolic process, small molecule metabolic process, sulfur compound metabolic process Golgi membrane, integral to membrane chondroitin 6-sulfotransferase activity, proteoglycan sulfotransferase activity, sulfotransferase activity Human CHST4 PINC UniProtKB {GO:0005802=PMID:12855678, GO:0006790=PMID:10330415, GO:0005975=GO_REF:0000037, GO:0031228=PMID:12855678, GO:0006044=PMID:10330415, GO:0007267=PMID:10330415, GO:0006928=PMID:10330415, GO:0050901=GO_REF:0000019, GO:0006955=PMID:10330415, GO:0006954=GO_REF:0000037, GO:0008146=PMID:10330415, GO:0006477=GO_REF:0000019, GO:0016021=GO_REF:0000037, GO:0001517=PMID:10330415, GO:0007155=PMID:10330415} Q8NCG5 Carbohydrate sulfotransferase 4 protein 20061107 {GO:0005802=IDA, GO:0006790=IDA, GO:0005975=IEA, GO:0031228=NAS, GO:0006044=IDA, GO:0007267=TAS, GO:0006928=TAS, GO:0050901=IEA, GO:0006955=TAS, GO:0006954=IEA, GO:0008146=TAS, GO:0006477=IEA, GO:0016021=IEA, GO:0001517=IDA, GO:0007155=TAS} N-acetylglucosamine metabolic process, carbohydrate metabolic process, cell adhesion, cell-cell signaling, cellular component movement, immune response, inflammatory response, leukocyte tethering or rolling, protein sulfation, sulfur compound metabolic process integral to membrane, intrinsic to Golgi membrane, trans-Golgi network N-acetylglucosamine 6-O-sulfotransferase activity, sulfotransferase activity Human CHST7 Reactome UniProtKB {GO:0006790=PMID:10913333, GO:0030206=Reactome:REACT_120989, GO:0000139=Reactome:REACT_120725, GO:0005976=PMID:10781596, GO:0005975=Reactome:REACT_474, GO:0006044=PMID:10913333, GO:0008459=PMID:10781596, GO:0044281=Reactome:REACT_111217, GO:0001517=PMID:10913333, GO:0016021=PMID:10913333, GO:0030204=Reactome:REACT_121206, GO:0030203=Reactome:REACT_121315} Q9NS84 Carbohydrate sulfotransferase 7 protein 20130301 {GO:0006790=IDA, GO:0030206=TAS, GO:0000139=TAS, GO:0005976=TAS, GO:0005975=TAS, GO:0006044=IDA, GO:0008459=IDA, GO:0044281=TAS, GO:0001517=IDA, GO:0016021=NAS, GO:0030204=TAS, GO:0030203=TAS} N-acetylglucosamine metabolic process, carbohydrate metabolic process, chondroitin sulfate biosynthetic process, chondroitin sulfate metabolic process, glycosaminoglycan metabolic process, polysaccharide metabolic process, small molecule metabolic process, sulfur compound metabolic process Golgi membrane, integral to membrane N-acetylglucosamine 6-O-sulfotransferase activity, chondroitin 6-sulfotransferase activity Human CHST9 Reactome UniProtKB {GO:0006790=PMID:11445554, GO:0005975=Reactome:REACT_474, GO:0005576=GO_REF:0000039, GO:0001537=PMID:11139592, GO:0044281=Reactome:REACT_111217, GO:0030166=GO_REF:0000024, GO:0016051=GO_REF:0000002, GO:0030206=Reactome:REACT_120989, GO:0000139=Reactome:REACT_121270, GO:0042446=GO_REF:0000024, GO:0016021=PMID:11139592, GO:0030204=Reactome:REACT_121206, GO:0030203=Reactome:REACT_121315} Q7L1S5 Carbohydrate sulfotransferase 9 protein 20130301 {GO:0006790=IDA, GO:0005975=TAS, GO:0005576=IEA, GO:0001537=IDA, GO:0044281=TAS, GO:0030166=ISS, GO:0016051=IEA, GO:0030206=TAS, GO:0000139=TAS, GO:0042446=ISS, GO:0016021=NAS, GO:0030204=TAS, GO:0030203=TAS} carbohydrate biosynthetic process, carbohydrate metabolic process, chondroitin sulfate biosynthetic process, chondroitin sulfate metabolic process, glycosaminoglycan metabolic process, hormone biosynthetic process, proteoglycan biosynthetic process, small molecule metabolic process, sulfur compound metabolic process Golgi membrane, extracellular region, integral to membrane N-acetylgalactosamine 4-O-sulfotransferase activity Human CHSY1 Reactome UniProtKB {GO:0005975=Reactome:REACT_474, GO:0005576=PMID:21129727, GO:0044281=Reactome:REACT_111217, GO:0050510=GO_REF:0000003, GO:0046872=GO_REF:0000037, GO:0030279=PMID:21129727, GO:0030206=Reactome:REACT_120989, GO:0000139=Reactome:REACT_121192, GO:0032580=GO_REF:0000039, GO:0031667=GO_REF:0000019, GO:0016021=GO_REF:0000037, GO:0030204=Reactome:REACT_121206, GO:0047238=PMID:11514575, GO:0030203=Reactome:REACT_121315} Q86X52 Chondroitin sulfate synthase 1 protein 20130301 {GO:0005975=TAS, GO:0005576=IDA, GO:0044281=TAS, GO:0050510=IEA, GO:0046872=IEA, GO:0030279=IMP, GO:0030206=TAS, GO:0000139=TAS, GO:0032580=IEA, GO:0031667=IEA, GO:0016021=IEA, GO:0030204=TAS, GO:0047238=IDA, GO:0030203=TAS} carbohydrate metabolic process, chondroitin sulfate biosynthetic process, chondroitin sulfate metabolic process, glycosaminoglycan metabolic process, negative regulation of ossification, response to nutrient levels, small molecule metabolic process Golgi cisterna membrane, Golgi membrane, extracellular region, integral to membrane N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity, glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity, metal ion binding Human CHTF18 UniProtKB UniProtKB {GO:0006260=GO_REF:0000037, GO:0005737=GO_REF:0000019, GO:0007049=GO_REF:0000037, GO:0017111=GO_REF:0000002, GO:0005634=GO_REF:0000039, GO:0003677=GO_REF:0000037, GO:0005524=GO_REF:0000037} Q8WVB6 Chromosome transmission fidelity protein 18 homolog protein 20130413 {GO:0006260=IEA, GO:0005737=IEA, GO:0007049=IEA, GO:0017111=IEA, GO:0005634=IEA, GO:0003677=IEA, GO:0005524=IEA} DNA replication, cell cycle cytoplasm, nucleus ATP binding, DNA binding, nucleoside-triphosphatase activity Human UniProtKB-SubCell:SL-0191 CHTF8 UniProtKB UniProtKB {GO:0006260=GO_REF:0000037, GO:0007049=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0003677=GO_REF:0000037} P0CG13 Chromosome transmission fidelity protein 8 homolog protein 20130413 {GO:0006260=IEA, GO:0007049=IEA, GO:0005634=IEA, GO:0003677=IEA} DNA replication, cell cycle nucleus DNA binding Human UniProtKB-SubCell:SL-0191 CHTOP HPA UniProtKB {GO:0005515=PMID:19858291, GO:0006355=GO_REF:0000037, GO:0003723=GO_REF:0000037, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0005654=GO_REF:0000039, GO:0006351=GO_REF:0000037, GO:0043231=GO_REF:0000052} Q9Y3Y2 Chromatin target of PRMT1 protein protein 20101115 {GO:0005515=IPI, GO:0006355=IEA, GO:0003723=IEA, GO:0005730=IDA, GO:0005634=IDA, GO:0005654=IEA, GO:0006351=IEA, GO:0043231=IDA} regulation of transcription, DNA-dependent, transcription, DNA-dependent intracellular membrane-bounded organelle, nucleolus, nucleoplasm, nucleus RNA binding, protein binding Human CHUK BHF-UCL UniProtKB {GO:0005515=PMID:22810585, GO:0035631=GO_REF:0000024, GO:0007249=PMID:18626576, GO:0009653=PMID:10747982, GO:0043231=GO_REF:0000052, GO:0042802=PMID:21765415, GO:0002756=Reactome:REACT_6809, GO:0007173=Reactome:REACT_9417, GO:0002755=Reactome:REACT_27215, GO:0032496=GO_REF:0000019, GO:0043123=Reactome:REACT_24918, GO:0033194=GO_REF:0000019, GO:0038124=Reactome:REACT_8006, GO:0046982=GO_REF:0000019, GO:0038123=Reactome:REACT_8005, GO:0034134=Reactome:REACT_7980, GO:0009636=GO_REF:0000019, GO:0002224=Reactome:REACT_9020, GO:0033598=GO_REF:0000019, GO:0008543=Reactome:REACT_9470, GO:0045087=Reactome:REACT_6802, GO:0009898=GO_REF:0000024, GO:0034166=Reactome:REACT_9027, GO:0035666=Reactome:REACT_25281, GO:0051146=GO_REF:0000019, GO:0034162=Reactome:REACT_9047, GO:0050852=Reactome:REACT_12526, GO:0034142=Reactome:REACT_6894, GO:0008384=PMID:18626576, GO:0008385=PMID:18626576, GO:0070423=Reactome:REACT_75776, GO:0005634=GO_REF:0000052, GO:0007266=GO_REF:0000019, GO:0035872=Reactome:REACT_75913, GO:0005829=Reactome:REACT_147740, GO:0005737=GO_REF:0000052, GO:0006955=PMID:9346484, GO:0006954=PMID:18626576, GO:0051092=Reactome:REACT_21281, GO:0042475=GO_REF:0000019, GO:0032481=Reactome:REACT_118823, GO:0043200=GO_REF:0000019, GO:0034138=Reactome:REACT_6783, GO:0048011=Reactome:REACT_11061, GO:0002011=GO_REF:0000019, GO:0042493=GO_REF:0000019, GO:0007252=PMID:9252186, GO:0048015=Reactome:REACT_12464, GO:0005730=GO_REF:0000052, GO:0030316=GO_REF:0000019, GO:0009615=PMID:18626576, GO:0005524=GO_REF:0000037, GO:0004672=PMID:20434986, GO:0003009=GO_REF:0000019, GO:0007595=GO_REF:0000019, GO:0006468=PMID:20434986, GO:0034146=Reactome:REACT_9061, GO:0060749=GO_REF:0000019} O15111 Inhibitor of nuclear factor kappa-B kinase subunit alpha protein 20110110 {GO:0005515=IPI, GO:0035631=ISS, GO:0007249=TAS, GO:0009653=TAS, GO:0043231=IDA, GO:0042802=IPI, GO:0002756=TAS, GO:0007173=TAS, GO:0002755=TAS, GO:0032496=IEA, GO:0043123=TAS, GO:0033194=IEA, GO:0038124=TAS, GO:0046982=IEA, GO:0038123=TAS, GO:0034134=TAS, GO:0009636=IEA, GO:0002224=TAS, GO:0033598=IEA, GO:0008543=TAS, GO:0045087=TAS, GO:0009898=ISS, GO:0034166=TAS, GO:0035666=TAS, GO:0051146=IEA, GO:0034162=TAS, GO:0050852=TAS, GO:0034142=TAS, GO:0008384=TAS, GO:0008385=TAS, GO:0070423=TAS, GO:0005634=IDA, GO:0007266=IEA, GO:0035872=TAS, GO:0005829=TAS, GO:0005737=IDA, GO:0006955=TAS, GO:0006954=TAS, GO:0051092=TAS, GO:0042475=IEA, GO:0032481=TAS, GO:0043200=IEA, GO:0034138=TAS, GO:0048011=TAS, GO:0002011=IEA, GO:0042493=IEA, GO:0007252=TAS, GO:0048015=TAS, GO:0005730=IDA, GO:0030316=IEA, GO:0009615=TAS, GO:0005524=IEA, GO:0004672=IDA, GO:0003009=IEA, GO:0007595=IEA, GO:0006468=IDA, GO:0034146=TAS, GO:0060749=IEA} I-kappaB kinase/NF-kappaB cascade, I-kappaB phosphorylation, MyD88-dependent toll-like receptor signaling pathway, MyD88-independent toll-like receptor signaling pathway, Rho protein signal transduction, T cell receptor signaling pathway, TRIF-dependent toll-like receptor signaling pathway, anatomical structure morphogenesis, epidermal growth factor receptor signaling pathway, fibroblast growth factor receptor signaling pathway, immune response, inflammatory response, innate immune response, lactation, mammary gland alveolus development, mammary gland epithelial cell proliferation, morphogenesis of an epithelial sheet, neurotrophin TRK receptor signaling pathway, nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway, nucleotide-binding oligomerization domain containing signaling pathway, odontogenesis of dentin-containing tooth, osteoclast differentiation, phosphatidylinositol-mediated signaling, positive regulation of I-kappaB kinase/NF-kappaB cascade, positive regulation of NF-kappaB transcription factor activity, positive regulation of type I interferon production, protein phosphorylation, response to amino acid stimulus, response to drug, response to hydroperoxide, response to lipopolysaccharide, response to toxic substance, response to virus, skeletal muscle contraction, striated muscle cell differentiation, toll-like receptor 10 signaling pathway, toll-like receptor 2 signaling pathway, toll-like receptor 3 signaling pathway, toll-like receptor 4 signaling pathway, toll-like receptor 5 signaling pathway, toll-like receptor 9 signaling pathway, toll-like receptor TLR1:TLR2 signaling pathway, toll-like receptor TLR6:TLR2 signaling pathway, toll-like receptor signaling pathway CD40 receptor complex, IkappaB kinase complex, cytoplasm, cytosol, internal side of plasma membrane, intracellular membrane-bounded organelle, nucleolus, nucleus ATP binding, IkappaB kinase activity, identical protein binding, protein binding, protein heterodimerization activity, protein kinase activity Human UniProtKB:Q60680 CHURC1 UniProtKB UniProtKB {GO:0008270=GO_REF:0000002, GO:0007275=GO_REF:0000037, GO:0045893=GO_REF:0000002, GO:0006351=GO_REF:0000037} Q8WUH1 Protein Churchill protein 20130413 {GO:0008270=IEA, GO:0007275=IEA, GO:0045893=IEA, GO:0006351=IEA} multicellular organismal development, positive regulation of transcription, DNA-dependent, transcription, DNA-dependent zinc ion binding Human UniProtKB-KW:KW-0217 CIAO1 Reactome UniProtKB {GO:0008284=PMID:9556563, GO:0007059=GO_REF:0000037, GO:0006357=PMID:9556563, GO:0016226=PMID:17937914, GO:0097361=PMID:22678361, GO:0044281=Reactome:REACT_111217, GO:0071817=PMID:20797633} O76071 Probable cytosolic iron-sulfur protein assembly protein CIAO1 protein 20120307 {GO:0008284=TAS, GO:0007059=IEA, GO:0006357=TAS, GO:0016226=IGI, GO:0097361=IDA, GO:0044281=TAS, GO:0071817=IDA} chromosome segregation, iron-sulfur cluster assembly, positive regulation of cell proliferation, regulation of transcription from RNA polymerase II promoter, small molecule metabolic process CIA complex, MMXD complex Human CIAPIN1 HPA UniProtKB {GO:0030097=GO_REF:0000019, GO:0043066=PMID:14970183, GO:0005737=PMID:16957168, GO:0051536=GO_REF:0000002, GO:0016226=GO_REF:0000002, GO:0008168=GO_REF:0000002, GO:0005730=GO_REF:0000052, GO:0006915=GO_REF:0000037, GO:0005634=GO_REF:0000052, GO:0044281=Reactome:REACT_111217} Q6FI81 Anamorsin protein 20110516 {GO:0030097=IEA, GO:0043066=ISS, GO:0005737=IDA, GO:0051536=IEA, GO:0016226=IEA, GO:0008168=IEA, GO:0005730=IDA, GO:0006915=IEA, GO:0005634=IDA, GO:0044281=TAS} apoptotic process, hemopoiesis, iron-sulfur cluster assembly, negative regulation of apoptotic process, small molecule metabolic process cytoplasm, nucleolus, nucleus iron-sulfur cluster binding, methyltransferase activity NOT Human CIB1 BHF-UCL UniProtKB {GO:0005515=PMID:20639889, GO:0008285=PMID:21264284, GO:0005783=PMID:10366599, GO:0005509=PMID:15475008, GO:0006915=PMID:10366599, GO:0030175=GO_REF:0000039, GO:0006974=PMID:12011095, GO:0006302=PMID:9372844, GO:0042383=PMID:20639889, GO:0016324=GO_REF:0000039, GO:0005737=PMID:20639889, GO:0016020=PMID:10366599, GO:0007113=PMID:21264284, GO:0005654=PMID:10366599, GO:0043495=PMID:20639889, GO:0007155=PMID:9030514, GO:0090004=PMID:20639889} Q99828 Calcium and integrin-binding protein 1 protein 20121209 {GO:0005515=IPI, GO:0008285=IMP, GO:0005783=IMP, GO:0005509=IMP, GO:0006915=IMP, GO:0030175=IEA, GO:0006974=IDA, GO:0006302=TAS, GO:0042383=IDA, GO:0016324=IEA, GO:0005737=IDA, GO:0016020=IDA, GO:0007113=IDA, GO:0005654=IMP, GO:0043495=IGI, GO:0007155=TAS, GO:0090004=IGI} apoptotic process, cell adhesion, double-strand break repair, endomitotic cell cycle, negative regulation of cell proliferation, positive regulation of establishment of protein localization to plasma membrane, response to DNA damage stimulus apical plasma membrane, cytoplasm, endoplasmic reticulum, filopodium, membrane, nucleoplasm, sarcolemma calcium ion binding, protein anchor, protein binding Human UniProtKB:Q63810-2 CIB2 UniProtKB UniProtKB {GO:0005515=PMID:23023331, GO:0001917=GO_REF:0000024, GO:0007229=GO_REF:0000038, GO:0005509=GO_REF:0000002, GO:0045494=GO_REF:0000024, GO:0055074=GO_REF:0000024} Q05BT6 CIB2 protein protein 20130413 {GO:0005515=IPI, GO:0001917=ISS, GO:0007229=IEA, GO:0005509=IEA, GO:0045494=ISS, GO:0055074=ISS} calcium ion homeostasis, integrin-mediated signaling pathway, photoreceptor cell maintenance photoreceptor inner segment calcium ion binding, protein binding Human UniProtKB-KW:KW-0401 CIC IntAct UniProtKB {GO:0005515=PMID:16713569, GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q96RK0 Protein capicua homolog protein 20130415 {GO:0005515=IPI, GO:0006355=IEA, GO:0005634=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus DNA binding, protein binding Human UniProtKB:Q9HC77 CIDEA BHF-UCL UniProtKB {GO:0006629=GO_REF:0000024, GO:0005811=PMID:18509062, GO:0008219=PMID:17080483, GO:0006355=GO_REF:0000037, GO:0035634=GO_REF:0000019, GO:0043066=PMID:17080483, GO:0001659=GO_REF:0000024, GO:0050995=GO_REF:0000024, GO:0008630=PMID:9564035, GO:0019915=GO_REF:0000024, GO:0006915=PMID:9564035, GO:0032720=PMID:15919794, GO:0005634=PMID:17080483, GO:0005740=GO_REF:0000024, GO:0050710=PMID:15919794, GO:0006351=GO_REF:0000037, GO:0042803=PMID:17080483, GO:0005739=GO_REF:0000024, GO:0005737=PMID:17080483, GO:0006309=PMID:9564035, GO:0010890=PMID:18509062, GO:0030512=PMID:17080483} O60543 Cell death activator CIDE-A protein 20121007 {GO:0006629=ISS, GO:0005811=IDA, GO:0008219=ISS, GO:0006355=IEA, GO:0035634=IEA, GO:0043066=ISS, GO:0001659=ISS, GO:0050995=ISS, GO:0008630=TAS, GO:0019915=ISS, GO:0006915=ISS, GO:0032720=IMP, GO:0005634=ISS, GO:0005740=ISS, GO:0050710=IMP, GO:0006351=IEA, GO:0042803=ISS, GO:0005739=ISS, GO:0005737=ISS, GO:0006309=ISS, GO:0010890=ISS, GO:0030512=ISS} apoptotic DNA fragmentation, apoptotic process, cell death, intrinsic apoptotic signaling pathway in response to DNA damage, lipid metabolic process, lipid storage, negative regulation of apoptotic process, negative regulation of cytokine secretion, negative regulation of lipid catabolic process, negative regulation of transforming growth factor beta receptor signaling pathway, negative regulation of tumor necrosis factor production, positive regulation of sequestering of triglyceride, regulation of transcription, DNA-dependent, response to stilbenoid, temperature homeostasis, transcription, DNA-dependent cytoplasm, lipid particle, mitochondrial envelope, mitochondrion, nucleus protein homodimerization activity Human UniProtKB:O70302 CIDEB MGI UniProtKB {GO:0008630=PMID:10619428, GO:0006917=PMID:12429024, GO:0005829=PMID:12429024} Q9UHD4 Cell death activator CIDE-B protein 20040116 {GO:0008630=TAS, GO:0006917=IDA, GO:0005829=IDA} induction of apoptosis, intrinsic apoptotic signaling pathway in response to DNA damage cytosol Human CIDEC HPA UniProtKB {GO:0005811=GO_REF:0000039, GO:0003674=GO_REF:0000015, GO:0005737=GO_REF:0000052, GO:0006355=GO_REF:0000037, GO:0005783=GO_REF:0000039, GO:0006915=GO_REF:0000037, GO:0005634=GO_REF:0000052, GO:0006917=PMID:12429024, GO:0005925=GO_REF:0000052, GO:0006351=GO_REF:0000037, GO:0005829=PMID:12429024} Q96AQ7 Cell death activator CIDE-3 protein 20100326 {GO:0005811=IEA, GO:0003674=ND, GO:0005737=IDA, GO:0006355=IEA, GO:0005783=IEA, GO:0006915=IEA, GO:0005634=IDA, GO:0006917=IDA, GO:0005925=IDA, GO:0006351=IEA, GO:0005829=IDA} apoptotic process, induction of apoptosis, regulation of transcription, DNA-dependent, transcription, DNA-dependent cytoplasm, cytosol, endoplasmic reticulum, focal adhesion, lipid particle, nucleus molecular_function Human CIITA BHF-UCL UniProtKB {GO:0005515=PMID:21890893, GO:0006355=GO_REF:0000002, GO:0044212=PMID:19041327, GO:0019221=Reactome:REACT_25229, GO:0003713=PMID:7749984, GO:0000122=PMID:19041327, GO:0008022=PMID:16600381, GO:0005524=GO_REF:0000037, GO:0003677=PMID:15771576, GO:0032403=PMID:17493635, GO:0006351=GO_REF:0000037, GO:0045348=PMID:9171108, GO:0006955=PMID:8402893, GO:0045345=PMID:20639463, GO:0032966=PMID:19041327, GO:0045944=PMID:20639463, GO:0016605=PMID:23007646, GO:0005654=Reactome:REACT_25082, GO:0034341=PMID:19041327, GO:0045893=PMID:19041327, GO:0033613=PMID:9171108, GO:0045892=PMID:19041327, GO:0046677=PMID:107465, GO:0060333=Reactome:REACT_25078} P33076 MHC class II transactivator protein 20110309 {GO:0005515=IPI, GO:0006355=IEA, GO:0044212=IDA, GO:0019221=TAS, GO:0003713=TAS, GO:0000122=IMP, GO:0008022=IPI, GO:0005524=IEA, GO:0003677=TAS, GO:0032403=IDA, GO:0006351=IEA, GO:0045348=IC, GO:0006955=TAS, GO:0045345=IDA, GO:0032966=IC, GO:0045944=IDA, GO:0016605=IDA, GO:0005654=TAS, GO:0034341=IDA, GO:0045893=IDA, GO:0033613=IPI, GO:0045892=IDA, GO:0046677=IDA, GO:0060333=TAS} cytokine-mediated signaling pathway, immune response, interferon-gamma-mediated signaling pathway, negative regulation of collagen biosynthetic process, negative regulation of transcription from RNA polymerase II promoter, negative regulation of transcription, DNA-dependent, positive regulation of MHC class I biosynthetic process, positive regulation of MHC class II biosynthetic process, positive regulation of transcription from RNA polymerase II promoter, positive regulation of transcription, DNA-dependent, regulation of transcription, DNA-dependent, response to antibiotic, response to interferon-gamma, transcription, DNA-dependent PML body, nucleoplasm ATP binding, DNA binding, activating transcription factor binding, protein C-terminus binding, protein binding, protein complex binding, transcription coactivator activity, transcription regulatory region DNA binding Human CINP UniProtKB UniProtKB {GO:0005515=PMID:21131973, GO:0006260=GO_REF:0000037, GO:0007049=GO_REF:0000037, GO:0006281=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0051301=GO_REF:0000037} Q9BW66 Cyclin-dependent kinase 2-interacting protein protein 20110502 {GO:0005515=IPI, GO:0006260=IEA, GO:0007049=IEA, GO:0006281=IEA, GO:0005634=IEA, GO:0051301=IEA} DNA repair, DNA replication, cell cycle, cell division nucleus protein binding Human UniProtKB:O94986 CIR1 BHF-UCL UniProtKB {GO:0005515=PMID:15652350, GO:0008380=GO_REF:0000037, GO:0006397=GO_REF:0000037, GO:0005737=GO_REF:0000037, GO:0003700=PMID:9874765, GO:0000118=PMID:9874765, GO:0016607=GO_REF:0000039, GO:0005815=GO_REF:0000039, GO:0003705=PMID:18663143, GO:0003714=PMID:9874765, GO:0005634=PMID:9874765, GO:0045892=PMID:9874765} Q86X95 Corepressor interacting with RBPJ 1 protein 20120925 {GO:0005515=IPI, GO:0008380=IEA, GO:0006397=IEA, GO:0005737=IEA, GO:0003700=TAS, GO:0000118=IDA, GO:0016607=IEA, GO:0005815=IEA, GO:0003705=TAS, GO:0003714=TAS, GO:0005634=IDA, GO:0045892=IDA} RNA splicing, mRNA processing, negative regulation of transcription, DNA-dependent cytoplasm, histone deacetylase complex, microtubule organizing center, nuclear speck, nucleus RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity, protein binding, sequence-specific DNA binding transcription factor activity, transcription corepressor activity Human CIRBP GOC UniProtKB {GO:0017148=GO_REF:0000024, GO:0005515=PMID:16513844, GO:0010494=GO_REF:0000024, GO:0009409=PMID:9151692, GO:0045727=PMID:11574538, GO:0005634=PMID:11574538, GO:0030371=GO_REF:0000024, GO:0003676=GO_REF:0000002, GO:0005737=GO_REF:0000024, GO:0034063=GO_REF:0000024, GO:0000166=GO_REF:0000002, GO:0070181=PMID:11574538, GO:0005654=GO_REF:0000039, GO:0048255=PMID:11574538, GO:0003730=PMID:16513844, GO:0009411=PMID:11574538} Q14011 Cold-inducible RNA-binding protein protein 20130413 {GO:0017148=ISS, GO:0005515=IPI, GO:0010494=ISS, GO:0009409=TAS, GO:0045727=IDA, GO:0005634=IDA, GO:0030371=ISS, GO:0003676=IEA, GO:0005737=ISS, GO:0034063=ISS, GO:0000166=IEA, GO:0070181=IDA, GO:0005654=IEA, GO:0048255=IDA, GO:0003730=IDA, GO:0009411=IDA} mRNA stabilization, negative regulation of translation, positive regulation of translation, response to UV, response to cold, stress granule assembly cytoplasm, cytoplasmic stress granule, nucleoplasm, nucleus SSU rRNA binding, mRNA 3'-UTR binding, nucleic acid binding, nucleotide binding, protein binding, translation repressor activity Human UniProtKB:P60824 CIRH1A UniProtKB UniProtKB {GO:0005515=PMID:19732766, GO:0003674=GO_REF:0000015, GO:0008150=GO_REF:0000015, GO:0006355=PMID:19732766, GO:0005730=PMID:16225863, GO:0006351=GO_REF:0000037} Q969X6 Cirhin protein 20120620 {GO:0005515=IPI, GO:0003674=ND, GO:0008150=ND, GO:0006355=IDA, GO:0005730=IDA, GO:0006351=IEA} biological_process, regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleolus molecular_function, protein binding Human UniProtKB:P15822 CISD1 UniProtKB UniProtKB {GO:0005739=GO_REF:0000024, GO:0051537=GO_REF:0000037, GO:0005741=GO_REF:0000039, GO:0016021=GO_REF:0000037, GO:0043457=GO_REF:0000019, GO:0046872=GO_REF:0000037} Q9NZ45 CDGSH iron-sulfur domain-containing protein 1 protein 20041006 {GO:0005739=ISS, GO:0051537=IEA, GO:0005741=IEA, GO:0016021=IEA, GO:0043457=IEA, GO:0046872=IEA} regulation of cellular respiration integral to membrane, mitochondrial outer membrane, mitochondrion 2 iron, 2 sulfur cluster binding, metal ion binding Human UniProtKB:Q91WS0 CISD2 HPA UniProtKB {GO:0005515=PMID:20010695, GO:0000422=GO_REF:0000019, GO:0051537=PMID:19580816, GO:0005783=GO_REF:0000052, GO:0010259=GO_REF:0000024, GO:0005741=GO_REF:0000024, GO:0046872=GO_REF:0000037, GO:0042803=PMID:19580816, GO:0043231=GO_REF:0000002, GO:0043234=GO_REF:0000054, GO:0005789=PMID:20010695, GO:0010506=PMID:20010695, GO:0016021=GO_REF:0000037} Q8N5K1 CDGSH iron-sulfur domain-containing protein 2 protein 20090616 {GO:0005515=IPI, GO:0000422=IEA, GO:0051537=IDA, GO:0005783=IDA, GO:0010259=ISS, GO:0005741=ISS, GO:0046872=IEA, GO:0042803=IDA, GO:0043231=IEA, GO:0043234=IDA, GO:0005789=IDA, GO:0010506=IMP, GO:0016021=IEA} mitochondrion degradation, multicellular organismal aging, regulation of autophagy endoplasmic reticulum, endoplasmic reticulum membrane, integral to membrane, intracellular membrane-bounded organelle, mitochondrial outer membrane, protein complex 2 iron, 2 sulfur cluster binding, metal ion binding, protein binding, protein homodimerization activity Human CISH Reactome UniProtKB {GO:0035556=PMID:10902923, GO:0003674=GO_REF:0000015, GO:0016567=GO_REF:0000041, GO:0005886=GO_REF:0000019, GO:0060397=Reactome:REACT_111133, GO:0005575=GO_REF:0000015, GO:0009968=GO_REF:0000037, GO:0001558=PMID:9465889, GO:0007205=GO_REF:0000019, GO:0005829=Reactome:REACT_111181} Q9NSE2 Cytokine-inducible SH2-containing protein protein 20130301 {GO:0035556=NAS, GO:0003674=ND, GO:0016567=IEA, GO:0005886=IEA, GO:0060397=TAS, GO:0005575=ND, GO:0009968=IEA, GO:0001558=NAS, GO:0007205=IEA, GO:0005829=TAS} JAK-STAT cascade involved in growth hormone signaling pathway, intracellular signal transduction, negative regulation of signal transduction, protein kinase C-activating G-protein coupled receptor signaling pathway, protein ubiquitination, regulation of cell growth cellular_component, cytosol, plasma membrane molecular_function Human CIT UniProtKB UniProtKB {GO:0005773=GO_REF:0000019, GO:0017124=GO_REF:0000037, GO:0048699=PMID:11086988, GO:0007283=GO_REF:0000019, GO:0015629=GO_REF:0000019, GO:0005524=GO_REF:0000037, GO:0001726=GO_REF:0000019, GO:0016358=GO_REF:0000019, GO:0046872=GO_REF:0000037, GO:0035556=GO_REF:0000002, GO:0007067=PMID:11086988, GO:0005083=GO_REF:0000002, GO:0000070=GO_REF:0000019, GO:0004672=GO_REF:0000002, GO:0005543=GO_REF:0000002, GO:0004674=PMID:9792683, GO:0050774=GO_REF:0000019, GO:0007091=GO_REF:0000019} O14578 Citron Rho-interacting kinase protein 20051020 {GO:0005773=IEA, GO:0017124=IEA, GO:0048699=ISS, GO:0007283=IEA, GO:0015629=IEA, GO:0005524=IEA, GO:0001726=IEA, GO:0016358=IEA, GO:0046872=IEA, GO:0035556=IEA, GO:0007067=ISS, GO:0005083=IEA, GO:0000070=IEA, GO:0004672=IEA, GO:0005543=IEA, GO:0004674=ISS, GO:0050774=IEA, GO:0007091=IEA} dendrite development, generation of neurons, intracellular signal transduction, metaphase/anaphase transition of mitotic cell cycle, mitosis, mitotic sister chromatid segregation, negative regulation of dendrite morphogenesis, spermatogenesis actin cytoskeleton, ruffle, vacuole ATP binding, SH3 domain binding, metal ion binding, phospholipid binding, protein kinase activity, protein serine/threonine kinase activity, small GTPase regulator activity Human UniProtKB:P49025 CITED1 BHF-UCL UniProtKB {GO:0001656=PMID:17336183, GO:0005515=PMID:11581164, GO:0060711=GO_REF:0000019, GO:0001658=GO_REF:0000024, GO:0043627=PMID:17938205, GO:0003700=PMID:8901575, GO:0044212=PMID:11581164, GO:0060712=GO_REF:0000019, GO:0051591=GO_REF:0000024, GO:0042803=PMID:21172805, GO:0043524=PMID:21172805, GO:0000578=GO_REF:0000019, GO:0042438=GO_REF:0000024, GO:0070670=GO_REF:0000024, GO:0032496=GO_REF:0000024, GO:0007179=PMID:9707553, GO:0032868=GO_REF:0000024, GO:0071107=GO_REF:0000024, GO:0071104=GO_REF:0000024, GO:0071105=GO_REF:0000024, GO:0003713=PMID:9707553, GO:0060231=PMID:17336183, GO:0001890=GO_REF:0000024, GO:0007420=GO_REF:0000019, GO:0070741=GO_REF:0000024, GO:0045893=PMID:9707553, GO:0045892=PMID:11581164, GO:0008283=PMID:17336183, GO:0030178=PMID:17336183, GO:0005634=PMID:9434189, GO:0060395=PMID:9707553, GO:0005829=PMID:16864582, GO:0005737=PMID:17710162, GO:0034341=GO_REF:0000024, GO:0034097=GO_REF:0000024, GO:0070555=GO_REF:0000024, GO:0071559=PMID:9707553, GO:0030511=PMID:17336183, GO:0006355=GO_REF:0000002, GO:0006357=PMID:9434189, GO:0070410=PMID:9707553, GO:0006915=GO_REF:0000037, GO:0030318=PMID:8901575, GO:0003340=GO_REF:0000019, GO:0008022=PMID:15843474, GO:0050693=PMID:11581164, GO:0006351=GO_REF:0000037, GO:0006913=PMID:16864582, GO:0010628=GO_REF:0000024, GO:0045668=GO_REF:0000024, GO:0003682=GO_REF:0000024, GO:0043473=PMID:8901575, GO:0001570=GO_REF:0000019, GO:0070669=GO_REF:0000024} Q99966 Cbp/p300-interacting transactivator 1 protein 20080923 {GO:0001656=TAS, GO:0005515=IPI, GO:0060711=IEA, GO:0001658=ISS, GO:0043627=TAS, GO:0003700=NAS, GO:0044212=IDA, GO:0060712=IEA, GO:0051591=ISS, GO:0042803=IDA, GO:0043524=IDA, GO:0000578=IEA, GO:0042438=ISS, GO:0070670=ISS, GO:0032496=ISS, GO:0007179=IDA, GO:0032868=ISS, GO:0071107=ISS, GO:0071104=ISS, GO:0071105=ISS, GO:0003713=IDA, GO:0060231=TAS, GO:0001890=ISS, GO:0007420=IEA, GO:0070741=ISS, GO:0045893=IDA, GO:0045892=IDA, GO:0008283=TAS, GO:0030178=TAS, GO:0005634=IDA, GO:0060395=IDA, GO:0005829=IDA, GO:0005737=IDA, GO:0034341=ISS, GO:0034097=ISS, GO:0070555=ISS, GO:0071559=IDA, GO:0030511=TAS, GO:0006355=IEA, GO:0006357=TAS, GO:0070410=IPI, GO:0006915=IEA, GO:0030318=IMP, GO:0003340=IEA, GO:0008022=IPI, GO:0050693=IDA, GO:0006351=IEA, GO:0006913=IDA, GO:0010628=ISS, GO:0045668=ISS, GO:0003682=ISS, GO:0043473=IMP, GO:0001570=IEA, GO:0070669=ISS} SMAD protein signal transduction, apoptotic process, brain development, branching involved in ureteric bud morphogenesis, cell proliferation, embryonic axis specification, labyrinthine layer development, melanin biosynthetic process, melanocyte differentiation, mesenchymal to epithelial transition, metanephros development, negative regulation of Wnt receptor signaling pathway, negative regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis, negative regulation of neuron apoptotic process, negative regulation of osteoblast differentiation, negative regulation of transcription, DNA-dependent, nucleocytoplasmic transport, pigmentation, placenta development, positive regulation of gene expression, positive regulation of transcription, DNA-dependent, positive regulation of transforming growth factor beta receptor signaling pathway, regulation of transcription from RNA polymerase II promoter, regulation of transcription, DNA-dependent, response to cAMP, response to cytokine stimulus, response to estrogen stimulus, response to insulin stimulus, response to interferon-gamma, response to interleukin-1, response to interleukin-11, response to interleukin-2, response to interleukin-4, response to interleukin-6, response to interleukin-9, response to lipopolysaccharide, response to parathyroid hormone stimulus, response to transforming growth factor beta stimulus, spongiotrophoblast layer development, transcription, DNA-dependent, transforming growth factor beta receptor signaling pathway, vasculogenesis cytoplasm, cytosol, nucleus LBD domain binding, chromatin binding, co-SMAD binding, protein C-terminus binding, protein binding, protein homodimerization activity, sequence-specific DNA binding transcription factor activity, transcription coactivator activity, transcription regulatory region DNA binding Human CITED2 BHF-UCL UniProtKB {GO:0005515=PMID:12586840, GO:0000790=GO_REF:0000024, GO:0043627=PMID:11581164, GO:0003700=GO_REF:0000024, GO:0034405=PMID:12960175, GO:0048538=GO_REF:0000019, GO:0046332=GO_REF:0000019, GO:0048536=GO_REF:0000024, GO:0048596=GO_REF:0000019, GO:0001947=GO_REF:0000019, GO:0007507=GO_REF:0000024, GO:1900164=GO_REF:0000024, GO:0007179=GO_REF:0000019, GO:0035802=GO_REF:0000024, GO:0035035=PMID:22735262, GO:0001102=GO_REF:0000019, GO:0030336=PMID:18054336, GO:0001105=GO_REF:0000019, GO:0022409=GO_REF:0000024, GO:0001106=PMID:22735262, GO:0007569=GO_REF:0000019, GO:0003714=PMID:17906695, GO:0003713=PMID:22735262, GO:0060136=GO_REF:0000019, GO:0001843=GO_REF:0000019, GO:0001892=GO_REF:0000019, GO:0000122=PMID:17906695, GO:0061428=PMID:22735262, GO:0007417=GO_REF:0000019, GO:0045787=GO_REF:0000024, GO:0001889=GO_REF:0000024, GO:0061156=GO_REF:0000019, GO:0060349=GO_REF:0000019, GO:0007422=GO_REF:0000019, GO:0045893=PMID:9434189, GO:0045892=PMID:15051727, GO:0007368=GO_REF:0000024, GO:0008283=PMID:15051727, GO:0005634=PMID:22735262, GO:0070986=GO_REF:0000024, GO:0007530=GO_REF:0000024, GO:0046697=GO_REF:0000019, GO:0035360=PMID:15051727, GO:0002089=GO_REF:0000019, GO:0002244=GO_REF:0000019, GO:0045944=PMID:22735262, GO:0048821=GO_REF:0000019, GO:0060971=GO_REF:0000024, GO:0030851=GO_REF:0000019, GO:0021602=GO_REF:0000019, GO:0030511=GO_REF:0000024, GO:0001666=PMID:17906695, GO:0043066=GO_REF:0000024, GO:0003197=GO_REF:0000019, GO:0060412=GO_REF:0000024, GO:0003156=GO_REF:0000024, GO:0050693=PMID:15051727, GO:0001829=GO_REF:0000019, GO:0003151=GO_REF:0000024, GO:0009612=GO_REF:0000019, GO:0010628=PMID:15051727, GO:0003682=GO_REF:0000024, GO:0061308=GO_REF:0000019, GO:0010629=PMID:15051727, GO:0001570=GO_REF:0000019, GO:0008584=GO_REF:0000019, GO:2000020=GO_REF:0000024} Q99967 Cbp/p300-interacting transactivator 2 protein 20120517 {GO:0005515=IPI, GO:0000790=ISS, GO:0043627=IDA, GO:0003700=ISS, GO:0034405=IMP, GO:0048538=IEA, GO:0046332=IEA, GO:0048536=ISS, GO:0048596=IEA, GO:0001947=IEA, GO:0007507=ISS, GO:1900164=ISS, GO:0007179=IEA, GO:0035802=ISS, GO:0035035=IDA, GO:0001102=IEA, GO:0030336=IMP, GO:0001105=IEA, GO:0022409=ISS, GO:0001106=IDA, GO:0007569=IEA, GO:0003714=IMP, GO:0003713=IDA, GO:0060136=IEA, GO:0001843=IEA, GO:0001892=IEA, GO:0000122=IMP, GO:0061428=IDA, GO:0007417=IEA, GO:0045787=ISS, GO:0001889=ISS, GO:0061156=IEA, GO:0060349=IEA, GO:0007422=IEA, GO:0045893=IDA, GO:0045892=IDA, GO:0007368=ISS, GO:0008283=IDA, GO:0005634=IDA, GO:0070986=ISS, GO:0007530=ISS, GO:0046697=IEA, GO:0035360=IDA, GO:0002089=IEA, GO:0002244=IEA, GO:0045944=IDA, GO:0048821=IEA, GO:0060971=ISS, GO:0030851=IEA, GO:0021602=IEA, GO:0030511=ISS, GO:0001666=IMP, GO:0043066=ISS, GO:0003197=IEA, GO:0060412=ISS, GO:0003156=ISS, GO:0050693=IPI, GO:0001829=IEA, GO:0003151=ISS, GO:0009612=IEA, GO:0010628=IDA, GO:0003682=ISS, GO:0061308=IEA, GO:0010629=IDA, GO:0001570=IEA, GO:0008584=IEA, GO:2000020=ISS} adrenal cortex formation, bone morphogenesis, cardiac neural crest cell development involved in heart development, cell aging, cell proliferation, central nervous system development, cranial nerve morphogenesis, decidualization, determination of left/right symmetry, embryonic camera-type eye morphogenesis, embryonic heart tube left/right pattern formation, embryonic placenta development, embryonic process involved in female pregnancy, endocardial cushion development, erythrocyte development, granulocyte differentiation, heart development, heart looping, hematopoietic progenitor cell differentiation, left/right axis specification, lens morphogenesis in camera-type eye, liver development, male gonad development, negative regulation of apoptotic process, negative regulation of cell migration, negative regulation of gene expression, negative regulation of transcription from RNA polymerase II promoter, negative regulation of transcription from RNA polymerase II promoter in response to hypoxia, negative regulation of transcription, DNA-dependent, neural tube closure, nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry, outflow tract morphogenesis, peripheral nervous system development, positive regulation of cell cycle, positive regulation of cell-cell adhesion, positive regulation of gene expression, positive regulation of male gonad development, positive regulation of peroxisome proliferator activated receptor signaling pathway, positive regulation of transcription from RNA polymerase II promoter, positive regulation of transcription, DNA-dependent, positive regulation of transforming growth factor beta receptor signaling pathway, pulmonary artery morphogenesis, regulation of organ formation, response to estrogen stimulus, response to fluid shear stress, response to hypoxia, response to mechanical stimulus, sex determination, spleen development, thymus development, transforming growth factor beta receptor signaling pathway, trophectodermal cell differentiation, vasculogenesis, ventricular septum morphogenesis nuclear chromatin, nucleus LBD domain binding, RNA polymerase II activating transcription factor binding, RNA polymerase II transcription coactivator activity, RNA polymerase II transcription corepressor activity, SMAD binding, chromatin binding, histone acetyltransferase binding, protein binding, sequence-specific DNA binding transcription factor activity, transcription coactivator activity, transcription corepressor activity Human UniProtKB:O35740 CITED4 UniProtKB UniProtKB {GO:0043627=GO_REF:0000024, GO:0005737=GO_REF:0000039, GO:0003713=GO_REF:0000024, GO:0005634=GO_REF:0000039, GO:0045893=GO_REF:0000019, GO:0006351=GO_REF:0000037} Q96RK1 Cbp/p300-interacting transactivator 4 protein 20110420 {GO:0043627=ISS, GO:0005737=IEA, GO:0003713=ISS, GO:0005634=IEA, GO:0045893=IEA, GO:0006351=IEA} positive regulation of transcription, DNA-dependent, response to estrogen stimulus, transcription, DNA-dependent cytoplasm, nucleus transcription coactivator activity Human UniProtKB:Q9WUL8 CIZ1 IntAct UniProtKB {GO:0005515=PMID:18654987, GO:0032298=GO_REF:0000019, GO:0030332=GO_REF:0000019, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0051658=GO_REF:0000019} Q9ULV3 Cip1-interacting zinc finger protein protein 20130415 {GO:0005515=IPI, GO:0032298=IEA, GO:0030332=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003676=IEA, GO:0051658=IEA} maintenance of nucleus location, positive regulation of DNA-dependent DNA replication initiation nucleus cyclin binding, nucleic acid binding, protein binding, zinc ion binding Human UniProtKB:Q9P0V3 CKAP2 HPA UniProtKB {GO:0005881=PMID:16061649, GO:0005813=PMID:21399614, GO:0000922=GO_REF:0000039, GO:0005737=GO_REF:0000052, GO:0000281=PMID:16061649, GO:0045944=PMID:16061649, GO:0015630=GO_REF:0000052, GO:0007026=GO_REF:0000019, GO:0006915=GO_REF:0000037} Q8WWK9 Cytoskeleton-associated protein 2 protein 20101115 {GO:0005881=IDA, GO:0005813=IDA, GO:0000922=IEA, GO:0005737=IDA, GO:0000281=IGI, GO:0045944=IGI, GO:0015630=IDA, GO:0007026=IEA, GO:0006915=IEA} apoptotic process, cytokinesis after mitosis, negative regulation of microtubule depolymerization, positive regulation of transcription from RNA polymerase II promoter centrosome, cytoplasm, cytoplasmic microtubule, microtubule cytoskeleton, spindle pole Human CKAP2L UniProtKB UniProtKB {GO:0005813=PMID:21399614} Q8IYA6 Cytoskeleton-associated protein 2-like protein 20110517 {GO:0005813=IDA} centrosome Human CKAP4 PINC UniProtKB {GO:0048471=GO_REF:0000039, GO:0016020=PMID:8314870, GO:0005886=GO_REF:0000039, GO:0005789=GO_REF:0000039, GO:0016021=GO_REF:0000037, GO:0005856=GO_REF:0000039} Q07065 Cytoskeleton-associated protein 4 protein 20030904 {GO:0048471=IEA, GO:0016020=TAS, GO:0005886=IEA, GO:0005789=IEA, GO:0016021=IEA, GO:0005856=IEA} cytoskeleton, endoplasmic reticulum membrane, integral to membrane, membrane, perinuclear region of cytoplasm, plasma membrane Human CKAP5 IntAct UniProtKB {GO:0005515=PMID:17474147, GO:0000236=Reactome:REACT_682, GO:0005813=PMID:14718566, GO:0030951=PMID:14718566, GO:0035371=PMID:21646404, GO:0050658=PMID:15703215, GO:0005829=Reactome:REACT_150414, GO:0051297=PMID:14718566, GO:0043234=PMID:18468998, GO:0000922=PMID:21646404, GO:0000086=Reactome:REACT_2203, GO:0000087=Reactome:REACT_910, GO:0015630=PMID:15703215, GO:0000930=PMID:14718566, GO:0007051=PMID:14718566, GO:0000278=Reactome:REACT_152, GO:0000090=Reactome:REACT_1275, GO:0051301=GO_REF:0000037} Q14008 Cytoskeleton-associated protein 5 protein 20130415 {GO:0005515=IPI, GO:0000236=TAS, GO:0005813=IDA, GO:0030951=IMP, GO:0035371=IDA, GO:0050658=ISS, GO:0005829=TAS, GO:0051297=IMP, GO:0043234=IDA, GO:0000922=IDA, GO:0000086=TAS, GO:0000087=TAS, GO:0015630=ISS, GO:0000930=IDA, GO:0007051=IMP, GO:0000278=TAS, GO:0000090=TAS, GO:0051301=IEA} G2/M transition of mitotic cell cycle, M phase of mitotic cell cycle, RNA transport, cell division, centrosome organization, establishment or maintenance of microtubule cytoskeleton polarity, mitotic anaphase, mitotic cell cycle, mitotic prometaphase, spindle organization centrosome, cytosol, gamma-tubulin complex, microtubule cytoskeleton, microtubule plus end, protein complex, spindle pole protein binding Human UniProtKB:P16333 CKB IntAct UniProtKB {GO:0005515=PMID:19060904, GO:0004111=GO_REF:0000003, GO:0005739=GO_REF:0000019, GO:0034641=Reactome:REACT_13, GO:0030644=GO_REF:0000019, GO:0006600=Reactome:REACT_813, GO:0007420=GO_REF:0000019, GO:0016301=GO_REF:0000038, GO:0044281=Reactome:REACT_111217, GO:0005524=GO_REF:0000037, GO:0005829=Reactome:REACT_11156} P12277 Creatine kinase B-type protein 20130415 {GO:0005515=IPI, GO:0004111=IEA, GO:0005739=IEA, GO:0034641=TAS, GO:0030644=IEA, GO:0006600=TAS, GO:0007420=IEA, GO:0016301=IEA, GO:0044281=TAS, GO:0005524=IEA, GO:0005829=TAS} brain development, cellular chloride ion homeostasis, cellular nitrogen compound metabolic process, creatine metabolic process, small molecule metabolic process cytosol, mitochondrion ATP binding, creatine kinase activity, kinase activity, protein binding Human UniProtKB:Q96DX5 CKLF UniProtKB UniProtKB {GO:0008009=PMID:11415443, GO:0008283=PMID:11415443, GO:0030593=PMID:11415443, GO:0005576=PMID:11415443, GO:0048247=PMID:11415443, GO:0016021=PMID:11415443, GO:0048246=PMID:11415443, GO:0032940=PMID:11415443, GO:0005615=GO_REF:0000037} Q9UBR5 Chemokine-like factor protein 20040408 {GO:0008009=IDA, GO:0008283=IDA, GO:0030593=IDA, GO:0005576=IDA, GO:0048247=IDA, GO:0016021=IDA, GO:0048246=IDA, GO:0032940=IDA, GO:0005615=IEA} cell proliferation, lymphocyte chemotaxis, macrophage chemotaxis, neutrophil chemotaxis, secretion by cell extracellular region, extracellular space, integral to membrane chemokine activity Human CKM Reactome UniProtKB {GO:0004111=GO_REF:0000003, GO:0034641=Reactome:REACT_13, GO:0005737=GO_REF:0000029, GO:0006600=Reactome:REACT_813, GO:0046314=GO_REF:0000019, GO:0044281=Reactome:REACT_111217, GO:0005524=GO_REF:0000037, GO:0005829=Reactome:REACT_11156} P06732 Creatine kinase M-type protein 20070718 {GO:0004111=IEA, GO:0034641=TAS, GO:0005737=NAS, GO:0006600=TAS, GO:0046314=IEA, GO:0044281=TAS, GO:0005524=IEA, GO:0005829=TAS} cellular nitrogen compound metabolic process, creatine metabolic process, phosphocreatine biosynthetic process, small molecule metabolic process cytoplasm, cytosol ATP binding, creatine kinase activity Human CKMT1A Reactome UniProtKB {GO:0005739=PMID:2914937, GO:0004111=GO_REF:0000003, GO:0034641=Reactome:REACT_13, GO:0006600=Reactome:REACT_813, GO:0016301=GO_REF:0000038, GO:0005743=Reactome:REACT_11155, GO:0044281=Reactome:REACT_111217, GO:0005524=GO_REF:0000037} P12532 Creatine kinase U-type, mitochondrial protein 20070718 {GO:0005739=TAS, GO:0004111=IEA, GO:0034641=TAS, GO:0006600=TAS, GO:0016301=IEA, GO:0005743=TAS, GO:0044281=TAS, GO:0005524=IEA} cellular nitrogen compound metabolic process, creatine metabolic process, small molecule metabolic process mitochondrial inner membrane, mitochondrion ATP binding, creatine kinase activity, kinase activity Human CKMT1B InterPro UniProtKB {GO:0016301=GO_REF:0000002, GO:0005524=GO_REF:0000038} J3KQ93 Creatine kinase U-type, mitochondrial protein 20130413 {GO:0016301=IEA, GO:0005524=IEA} ATP binding, kinase activity Human InterPro:IPR022414 CKMT2 Reactome UniProtKB {GO:0004111=GO_REF:0000003, GO:0005739=PMID:2324105, GO:0034641=Reactome:REACT_13, GO:0006936=PMID:2324105, GO:0006600=Reactome:REACT_813, GO:0016301=GO_REF:0000002, GO:0005743=Reactome:REACT_11155, GO:0044281=Reactome:REACT_111217, GO:0005524=GO_REF:0000037} P17540 Creatine kinase S-type, mitochondrial protein 20070718 {GO:0004111=IEA, GO:0005739=TAS, GO:0034641=TAS, GO:0006936=TAS, GO:0006600=TAS, GO:0016301=IEA, GO:0005743=TAS, GO:0044281=TAS, GO:0005524=IEA} cellular nitrogen compound metabolic process, creatine metabolic process, muscle contraction, small molecule metabolic process mitochondrial inner membrane, mitochondrion ATP binding, creatine kinase activity, kinase activity Human CKS1B UniProtKB UniProtKB {GO:0005515=PMID:12813041, GO:0000084=Reactome:REACT_899, GO:0007049=GO_REF:0000002, GO:0000082=Reactome:REACT_1783, GO:0016301=GO_REF:0000038, GO:0008283=PMID:2227411, GO:0005654=Reactome:REACT_111194, GO:0016538=GO_REF:0000002, GO:0000079=PMID:8601310, GO:0000278=Reactome:REACT_152, GO:0000080=Reactome:REACT_1590, GO:0051301=GO_REF:0000037} Q9BZU3 PNAS-18 protein 20130413 {GO:0005515=IPI, GO:0000084=TAS, GO:0007049=IEA, GO:0000082=TAS, GO:0016301=IEA, GO:0008283=TAS, GO:0005654=TAS, GO:0016538=IEA, GO:0000079=TAS, GO:0000278=TAS, GO:0000080=TAS, GO:0051301=IEA} G1 phase of mitotic cell cycle, G1/S transition of mitotic cell cycle, S phase of mitotic cell cycle, cell cycle, cell division, cell proliferation, mitotic cell cycle, regulation of cyclin-dependent protein serine/threonine kinase activity nucleoplasm cyclin-dependent protein serine/threonine kinase regulator activity, kinase activity, protein binding Human UniProtKB-KW:KW-0418 CKS2 PINC UniProtKB {GO:0007049=PMID:15504738, GO:0007127=GO_REF:0000019, GO:0008283=PMID:8211159, GO:0048015=PMID:15504738, GO:0016538=GO_REF:0000002, GO:0000079=PMID:2227411, GO:0007051=PMID:15504738, GO:0051301=GO_REF:0000037} P33552 Cyclin-dependent kinases regulatory subunit 2 protein 20030904 {GO:0007049=NAS, GO:0007127=IEA, GO:0008283=TAS, GO:0048015=NAS, GO:0016538=IEA, GO:0000079=TAS, GO:0007051=NAS, GO:0051301=IEA} cell cycle, cell division, cell proliferation, meiosis I, phosphatidylinositol-mediated signaling, regulation of cyclin-dependent protein serine/threonine kinase activity, spindle organization cyclin-dependent protein serine/threonine kinase regulator activity Human CLASP1 IntAct UniProtKB {GO:0005515=PMID:11290329, GO:0005828=PMID:12837247, GO:0008017=PMID:12837247, GO:0000236=Reactome:REACT_682, GO:0005881=PMID:11290329, GO:0030981=PMID:12837247, GO:0034453=PMID:17543864, GO:0001578=PMID:12837247, GO:0051294=PMID:21822276, GO:0005829=Reactome:REACT_150414, GO:0051010=PMID:12837247, GO:0007411=Reactome:REACT_18266, GO:0000086=Reactome:REACT_2203, GO:0031023=PMID:17543864, GO:0000087=Reactome:REACT_910, GO:0005876=PMID:12837247, GO:0005938=PMID:17113391, GO:0010458=PMID:16866869, GO:0005813=PMID:21399614, GO:0005794=PMID:15631994, GO:0031111=PMID:12837247, GO:0000226=PMID:15631994, GO:0007163=PMID:15928712, GO:0007020=PMID:17543864, GO:0000777=GO_REF:0000039, GO:0007026=PMID:16866869, GO:0000776=PMID:12837247, GO:0043515=PMID:12837247, GO:0000278=Reactome:REACT_152, GO:0000090=Reactome:REACT_1275, GO:0031592=PMID:16914514, GO:0051301=PMID:21822276} Q7Z460 CLIP-associating protein 1 protein 20130415 {GO:0005515=IPI, GO:0005828=TAS, GO:0008017=IMP, GO:0000236=TAS, GO:0005881=IDA, GO:0030981=IDA, GO:0034453=IMP, GO:0001578=IMP, GO:0051294=IMP, GO:0005829=TAS, GO:0051010=IDA, GO:0007411=TAS, GO:0000086=TAS, GO:0031023=IMP, GO:0000087=TAS, GO:0005876=IDA, GO:0005938=IDA, GO:0010458=IMP, GO:0005813=IDA, GO:0005794=IDA, GO:0031111=IMP, GO:0000226=IGI, GO:0007163=NAS, GO:0007020=IMP, GO:0000777=IEA, GO:0007026=IMP, GO:0000776=IDA, GO:0043515=IMP, GO:0000278=TAS, GO:0000090=TAS, GO:0031592=IDA, GO:0051301=IDA} G2/M transition of mitotic cell cycle, M phase of mitotic cell cycle, axon guidance, cell division, establishment of spindle orientation, establishment or maintenance of cell polarity, exit from mitosis, microtubule anchoring, microtubule bundle formation, microtubule cytoskeleton organization, microtubule nucleation, microtubule organizing center organization, mitotic anaphase, mitotic cell cycle, mitotic prometaphase, negative regulation of microtubule depolymerization, negative regulation of microtubule polymerization or depolymerization Golgi apparatus, cell cortex, centrosomal corona, centrosome, condensed chromosome kinetochore, cortical microtubule cytoskeleton, cytoplasmic microtubule, cytosol, kinetochore, kinetochore microtubule, spindle microtubule kinetochore binding, microtubule binding, microtubule plus-end binding, protein binding Human UniProtKB:O55156 CLASP2 IntAct UniProtKB {GO:0005828=PMID:12837247, GO:0008017=GO_REF:0000019, GO:0005515=PMID:11290329, GO:0005802=PMID:17543864, GO:0000236=Reactome:REACT_682, GO:0005881=PMID:11290329, GO:0034453=PMID:17543864, GO:0005886=PMID:20937854, GO:0005829=Reactome:REACT_150414, GO:0005737=PMID:11290329, GO:0051010=PMID:19632184, GO:0007411=Reactome:REACT_18266, GO:0008107=PMID:11290329, GO:0031023=PMID:17543864, GO:0000087=Reactome:REACT_910, GO:0005938=PMID:17113391, GO:0005794=PMID:11290329, GO:0005815=GO_REF:0000039, GO:0031110=PMID:11290329, GO:0005874=PMID:20937854, GO:0032886=PMID:20937854, GO:0032587=PMID:20937854, GO:0007163=PMID:15928712, GO:0016477=GO_REF:0000019, GO:0007020=PMID:17543864, GO:0000777=GO_REF:0000039, GO:0007026=PMID:11290329, GO:0000278=Reactome:REACT_152, GO:0000090=Reactome:REACT_1275, GO:0051301=GO_REF:0000037} O75122 CLIP-associating protein 2 protein 20130415 {GO:0005828=TAS, GO:0008017=IEA, GO:0005515=IPI, GO:0005802=IDA, GO:0000236=TAS, GO:0005881=IDA, GO:0034453=IMP, GO:0005886=IDA, GO:0005829=TAS, GO:0005737=NAS, GO:0051010=IDA, GO:0007411=TAS, GO:0008107=NAS, GO:0031023=IMP, GO:0000087=TAS, GO:0005938=IDA, GO:0005794=IDA, GO:0005815=IEA, GO:0031110=IMP, GO:0005874=IDA, GO:0032886=IMP, GO:0032587=IDA, GO:0007163=TAS, GO:0016477=IEA, GO:0007020=IMP, GO:0000777=IEA, GO:0007026=NAS, GO:0000278=TAS, GO:0000090=TAS, GO:0051301=IEA} M phase of mitotic cell cycle, axon guidance, cell division, cell migration, establishment or maintenance of cell polarity, microtubule anchoring, microtubule nucleation, microtubule organizing center organization, mitotic anaphase, mitotic cell cycle, mitotic prometaphase, negative regulation of microtubule depolymerization, regulation of microtubule polymerization or depolymerization, regulation of microtubule-based process Golgi apparatus, cell cortex, condensed chromosome kinetochore, cytoplasm, cytoplasmic microtubule, cytosol, kinetochore microtubule, microtubule, microtubule organizing center, plasma membrane, ruffle membrane, trans-Golgi network galactoside 2-alpha-L-fucosyltransferase activity, microtubule binding, microtubule plus-end binding, protein binding Human UniProtKB:O55156 CLASRP UniProtKB UniProtKB {GO:0008380=GO_REF:0000037, GO:0006397=GO_REF:0000037, GO:0005634=GO_REF:0000039} Q8N2M8 CLK4-associating serine/arginine rich protein protein 20130413 {GO:0008380=IEA, GO:0006397=IEA, GO:0005634=IEA} RNA splicing, mRNA processing nucleus Human UniProtKB-SubCell:SL-0191 CLCA1 GOC UniProtKB {GO:0006821=PMID:9828122, GO:0005887=PMID:9828122, GO:0006810=PMID:9828122, GO:0006816=GO_REF:0000037, GO:0030141=GO_REF:0000019, GO:0005254=PMID:9828122, GO:0005615=GO_REF:0000039} A8K7I4 Calcium-activated chloride channel regulator 1 protein 20130413 {GO:0006821=TAS, GO:0005887=TAS, GO:0006810=TAS, GO:0006816=IEA, GO:0030141=IEA, GO:0005254=TAS, GO:0005615=IEA} calcium ion transport, chloride transport, transport extracellular space, integral to plasma membrane, secretory granule chloride channel activity Human CLCA2 PINC UniProtKB {GO:0030054=GO_REF:0000039, GO:0009925=GO_REF:0000039, GO:0005887=PMID:10362588, GO:0006810=PMID:10362588, GO:0005576=GO_REF:0000039, GO:0007155=GO_REF:0000037, GO:0005254=GO_REF:0000019, GO:0015276=GO_REF:0000019} Q9UQC9 Calcium-activated chloride channel regulator 2 protein 20090630 {GO:0030054=IEA, GO:0009925=IEA, GO:0005887=TAS, GO:0006810=TAS, GO:0005576=IEA, GO:0007155=IEA, GO:0005254=IEA, GO:0015276=IEA} cell adhesion, transport basal plasma membrane, cell junction, extracellular region, integral to plasma membrane chloride channel activity, ligand-gated ion channel activity Human CLCC1 HPA UniProtKB {GO:0005794=GO_REF:0000039, GO:0005783=GO_REF:0000052, GO:0005634=GO_REF:0000039, GO:0016021=GO_REF:0000037, GO:0043231=GO_REF:0000052} Q96S66 Chloride channel CLIC-like protein 1 protein 20101115 {GO:0005794=IEA, GO:0005783=IDA, GO:0005634=IEA, GO:0016021=IEA, GO:0043231=IDA} Golgi apparatus, endoplasmic reticulum, integral to membrane, intracellular membrane-bounded organelle, nucleus Human CLCF1 BHF-UCL UniProtKB {GO:0005515=PMID:10966616, GO:0043066=PMID:14632778, GO:0008284=PMID:11285233, GO:0048295=GO_REF:0000024, GO:0046982=PMID:10966616, GO:0030890=GO_REF:0000024, GO:0042517=PMID:11285233, GO:0019221=PMID:10500198, GO:0097059=PMID:11285233, GO:0005102=PMID:15272019, GO:0005576=PMID:10966616, GO:0005125=PMID:10966616, GO:0007259=GO_REF:0000024, GO:0097058=PMID:10966616, GO:0005127=PMID:11285233, GO:0043524=PMID:11285233, GO:0048711=GO_REF:0000024, GO:0002639=GO_REF:0000024, GO:0030183=GO_REF:0000024, GO:0008083=PMID:14632778, GO:0007166=GO_REF:0000024} Q9UBD9 Cardiotrophin-like cytokine factor 1 protein 20120404 {GO:0005515=IPI, GO:0043066=TAS, GO:0008284=IDA, GO:0048295=ISS, GO:0046982=IDA, GO:0030890=ISS, GO:0042517=IDA, GO:0019221=NAS, GO:0097059=IDA, GO:0005102=IPI, GO:0005576=IDA, GO:0005125=IDA, GO:0007259=ISS, GO:0097058=IDA, GO:0005127=IDA, GO:0043524=IDA, GO:0048711=ISS, GO:0002639=ISS, GO:0030183=ISS, GO:0008083=TAS, GO:0007166=ISS} B cell differentiation, JAK-STAT cascade, cell surface receptor signaling pathway, cytokine-mediated signaling pathway, negative regulation of apoptotic process, negative regulation of neuron apoptotic process, positive regulation of B cell proliferation, positive regulation of astrocyte differentiation, positive regulation of cell proliferation, positive regulation of immunoglobulin production, positive regulation of isotype switching to IgE isotypes, positive regulation of tyrosine phosphorylation of Stat3 protein CNTFR-CLCF1 complex, CRLF-CLCF1 complex, extracellular region ciliary neurotrophic factor receptor binding, cytokine activity, growth factor activity, protein binding, protein heterodimerization activity, receptor binding Human CLCN1 Reactome UniProtKB {GO:0042383=GO_REF:0000019, GO:0034220=Reactome:REACT_25300, GO:0006936=PMID:1379744, GO:0005886=Reactome:REACT_160109, GO:0016020=GO_REF:0000002, GO:0005887=PMID:9122265, GO:0005247=GO_REF:0000002, GO:0006810=PMID:9122265, GO:0034707=GO_REF:0000037, GO:0055085=Reactome:REACT_15518, GO:0005254=PMID:1379744, GO:0019227=GO_REF:0000019} P35523 Chloride channel protein 1 protein 20130301 {GO:0042383=IEA, GO:0034220=TAS, GO:0006936=TAS, GO:0005886=TAS, GO:0016020=IEA, GO:0005887=TAS, GO:0005247=IEA, GO:0006810=TAS, GO:0034707=IEA, GO:0055085=TAS, GO:0005254=TAS, GO:0019227=IEA} ion transmembrane transport, muscle contraction, neuronal action potential propagation, transmembrane transport, transport chloride channel complex, integral to plasma membrane, membrane, plasma membrane, sarcolemma chloride channel activity, voltage-gated chloride channel activity Human CLCN2 Reactome UniProtKB {GO:0034220=Reactome:REACT_25300, GO:0005886=Reactome:REACT_160109, GO:0060041=GO_REF:0000019, GO:0005247=GO_REF:0000019, GO:0006810=PMID:7795595, GO:0034707=GO_REF:0000037, GO:0055085=Reactome:REACT_15518, GO:0060689=GO_REF:0000019} P51788 Chloride channel protein 2 protein 20130301 {GO:0034220=TAS, GO:0005886=TAS, GO:0060041=IEA, GO:0005247=IEA, GO:0006810=TAS, GO:0034707=IEA, GO:0055085=TAS, GO:0060689=IEA} cell differentiation involved in salivary gland development, ion transmembrane transport, retina development in camera-type eye, transmembrane transport, transport chloride channel complex, plasma membrane voltage-gated chloride channel activity Human CLCN3 Reactome UniProtKB {GO:0005515=PMID:12471024, GO:0005254=PMID:12471024, GO:0006885=PMID:12471024, GO:0042803=PMID:12471024, GO:0005622=GO_REF:0000019, GO:0016324=GO_REF:0000019, GO:0015297=GO_REF:0000037, GO:0034220=Reactome:REACT_25300, GO:0006810=PMID:7665160, GO:0030658=GO_REF:0000039, GO:0012506=PMID:12471024, GO:0005794=PMID:12471024, GO:0046982=PMID:12471024, GO:0009986=PMID:12471024, GO:0005770=PMID:12471024, GO:0005247=GO_REF:0000019, GO:0030165=PMID:12471024, GO:0055085=Reactome:REACT_15518, GO:0005524=GO_REF:0000037, GO:0000139=GO_REF:0000039, GO:0016020=GO_REF:0000002, GO:0048388=PMID:12471024, GO:0031901=GO_REF:0000039, GO:0031902=Reactome:REACT_160116, GO:0016021=PMID:12471024, GO:0005769=PMID:12471024} P51790 H(+)/Cl(-) exchange transporter 3 protein 20130301 {GO:0005515=IPI, GO:0005254=TAS, GO:0006885=TAS, GO:0042803=NAS, GO:0005622=IEA, GO:0016324=IEA, GO:0015297=IEA, GO:0034220=TAS, GO:0006810=TAS, GO:0030658=IEA, GO:0012506=IDA, GO:0005794=IDA, GO:0046982=IDA, GO:0009986=NAS, GO:0005770=IDA, GO:0005247=IEA, GO:0030165=IDA, GO:0055085=TAS, GO:0005524=IEA, GO:0000139=IEA, GO:0016020=IEA, GO:0048388=TAS, GO:0031901=IEA, GO:0031902=TAS, GO:0016021=TAS, GO:0005769=IDA} endosomal lumen acidification, ion transmembrane transport, regulation of pH, transmembrane transport, transport Golgi apparatus, Golgi membrane, apical plasma membrane, cell surface, early endosome, early endosome membrane, integral to membrane, intracellular, late endosome, late endosome membrane, membrane, transport vesicle membrane, vesicle membrane ATP binding, PDZ domain binding, antiporter activity, chloride channel activity, protein binding, protein heterodimerization activity, protein homodimerization activity, voltage-gated chloride channel activity Human CLCN4 Reactome UniProtKB {GO:0006821=PMID:10564087, GO:0005247=GO_REF:0000002, GO:0005524=GO_REF:0000037, GO:0005254=PMID:10564087, GO:0055085=Reactome:REACT_15518, GO:0015297=GO_REF:0000037, GO:0034220=Reactome:REACT_25300, GO:0031901=GO_REF:0000039, GO:0031902=GO_REF:0000039, GO:0006810=PMID:8069296, GO:0016021=GO_REF:0000037, GO:0005216=GO_REF:0000002, GO:0010008=Reactome:REACT_160268} P51793 H(+)/Cl(-) exchange transporter 4 protein 20130301 {GO:0006821=IDA, GO:0005247=IEA, GO:0005524=IEA, GO:0005254=IDA, GO:0055085=TAS, GO:0015297=IEA, GO:0034220=TAS, GO:0031901=IEA, GO:0031902=IEA, GO:0006810=TAS, GO:0016021=IEA, GO:0005216=IEA, GO:0010008=TAS} chloride transport, ion transmembrane transport, transmembrane transport, transport early endosome membrane, endosome membrane, integral to membrane, late endosome membrane ATP binding, antiporter activity, chloride channel activity, ion channel activity, voltage-gated chloride channel activity Human CLCN5 Reactome UniProtKB {GO:0007588=PMID:8559248, GO:0005247=GO_REF:0000002, GO:0045177=PMID:14675051, GO:0055085=Reactome:REACT_15518, GO:0005524=GO_REF:0000037, GO:0005254=PMID:8559248, GO:0006897=GO_REF:0000019, GO:0015297=GO_REF:0000037, GO:0034220=Reactome:REACT_25300, GO:0000139=GO_REF:0000039, GO:0016020=PMID:14675051, GO:0005887=PMID:8559248, GO:0006810=PMID:8559248, GO:0010008=Reactome:REACT_160268} P51795 H(+)/Cl(-) exchange transporter 5 protein 20130301 {GO:0007588=TAS, GO:0005247=IEA, GO:0045177=IDA, GO:0055085=TAS, GO:0005524=IEA, GO:0005254=TAS, GO:0006897=IEA, GO:0015297=IEA, GO:0034220=TAS, GO:0000139=IEA, GO:0016020=IDA, GO:0005887=TAS, GO:0006810=TAS, GO:0010008=TAS} endocytosis, excretion, ion transmembrane transport, transmembrane transport, transport Golgi membrane, apical part of cell, endosome membrane, integral to plasma membrane, membrane ATP binding, antiporter activity, chloride channel activity, voltage-gated chloride channel activity Human CLCN6 InterPro UniProtKB {GO:0007165=PMID:9224655, GO:0006821=PMID:8543009, GO:0034220=Reactome:REACT_25300, GO:0015297=GO_REF:0000037, GO:0016020=GO_REF:0000002, GO:0005247=GO_REF:0000002, GO:0016021=PMID:8543009, GO:0055085=Reactome:REACT_15518, GO:0005524=GO_REF:0000037, GO:0010008=Reactome:REACT_160268, GO:0006884=PMID:8543009} Q5SNW4 Chloride transport protein 6 protein 20130413 {GO:0007165=NAS, GO:0006821=NAS, GO:0034220=TAS, GO:0015297=IEA, GO:0016020=IEA, GO:0005247=IEA, GO:0016021=NAS, GO:0055085=TAS, GO:0005524=IEA, GO:0010008=TAS, GO:0006884=NAS} cell volume homeostasis, chloride transport, ion transmembrane transport, signal transduction, transmembrane transport endosome membrane, integral to membrane, membrane ATP binding, antiporter activity, voltage-gated chloride channel activity Human InterPro:IPR002248 CLCN7 Reactome UniProtKB {GO:0034220=Reactome:REACT_25300, GO:0015297=GO_REF:0000037, GO:0016020=GO_REF:0000002, GO:0005247=GO_REF:0000002, GO:0006810=PMID:8543009, GO:0016021=GO_REF:0000037, GO:0031410=GO_REF:0000019, GO:0005765=Reactome:REACT_160230, GO:0055085=Reactome:REACT_15518, GO:0005254=PMID:8543009, GO:0005524=GO_REF:0000037, GO:0009268=GO_REF:0000019} P51798 H(+)/Cl(-) exchange transporter 7 protein 20121126 {GO:0034220=TAS, GO:0015297=IEA, GO:0016020=IEA, GO:0005247=IEA, GO:0006810=TAS, GO:0016021=IEA, GO:0031410=IEA, GO:0005765=TAS, GO:0055085=TAS, GO:0005254=TAS, GO:0005524=IEA, GO:0009268=IEA} ion transmembrane transport, response to pH, transmembrane transport, transport cytoplasmic vesicle, integral to membrane, lysosomal membrane, membrane ATP binding, antiporter activity, chloride channel activity, voltage-gated chloride channel activity Human CLCNKA Reactome UniProtKB {GO:0007588=PMID:8041726, GO:0034220=Reactome:REACT_25300, GO:0005886=Reactome:REACT_160109, GO:0005887=PMID:8041726, GO:0005247=GO_REF:0000002, GO:0006810=PMID:8041726, GO:0034707=GO_REF:0000037, GO:0055085=Reactome:REACT_15518} P51800 Chloride channel protein ClC-Ka protein 20121126 {GO:0007588=TAS, GO:0034220=TAS, GO:0005886=TAS, GO:0005887=TAS, GO:0005247=IEA, GO:0006810=TAS, GO:0034707=IEA, GO:0055085=TAS} excretion, ion transmembrane transport, transmembrane transport, transport chloride channel complex, integral to plasma membrane, plasma membrane voltage-gated chloride channel activity Human CLCNKB Reactome UniProtKB {GO:0007588=PMID:9326936, GO:0034220=Reactome:REACT_25300, GO:0005886=Reactome:REACT_160109, GO:0005887=PMID:8041726, GO:0005247=GO_REF:0000002, GO:0006810=PMID:8041726, GO:0034707=GO_REF:0000037, GO:0055085=Reactome:REACT_15518} P51801 Chloride channel protein ClC-Kb protein 20121126 {GO:0007588=TAS, GO:0034220=TAS, GO:0005886=TAS, GO:0005887=TAS, GO:0005247=IEA, GO:0006810=TAS, GO:0034707=IEA, GO:0055085=TAS} excretion, ion transmembrane transport, transmembrane transport, transport chloride channel complex, integral to plasma membrane, plasma membrane voltage-gated chloride channel activity Human CLDN1 MGI UniProtKB {GO:0016324=GO_REF:0000019, GO:0016338=GO_REF:0000024, GO:0005887=PMID:9647647, GO:0005198=GO_REF:0000002, GO:0019048=GO_REF:0000037, GO:0016021=PMID:9931503, GO:0005923=GO_REF:0000024, GO:0007155=PMID:9647647, GO:0016328=GO_REF:0000019, GO:0045216=PMID:20164257, GO:0042802=GO_REF:0000024} O95832 Claudin-1 protein 20120514 {GO:0016324=IEA, GO:0016338=ISS, GO:0005887=TAS, GO:0005198=IEA, GO:0019048=IEA, GO:0016021=TAS, GO:0005923=ISS, GO:0007155=TAS, GO:0016328=IEA, GO:0045216=IMP, GO:0042802=ISS} calcium-independent cell-cell adhesion, cell adhesion, cell-cell junction organization, virus-host interaction apical plasma membrane, integral to membrane, integral to plasma membrane, lateral plasma membrane, tight junction identical protein binding, structural molecule activity Human CLDN10 ENSEMBL UniProtKB {GO:0016338=GO_REF:0000024, GO:0016020=GO_REF:0000002, GO:0005886=GO_REF:0000039, GO:0005198=GO_REF:0000002, GO:0005923=GO_REF:0000019, GO:0016021=GO_REF:0000037, GO:0007155=PMID:10508613, GO:0042802=GO_REF:0000024} Q5W075 Claudin-10 protein 20130413 {GO:0016338=ISS, GO:0016020=IEA, GO:0005886=IEA, GO:0005198=IEA, GO:0005923=IEA, GO:0016021=IEA, GO:0007155=TAS, GO:0042802=ISS} calcium-independent cell-cell adhesion, cell adhesion integral to membrane, membrane, plasma membrane, tight junction identical protein binding, structural molecule activity Human Ensembl:ENSMUSP00000097889 CLDN11 UniProtKB UniProtKB {GO:0016338=GO_REF:0000024, GO:0005886=GO_REF:0000039, GO:0005198=GO_REF:0000002, GO:0007283=GO_REF:0000019, GO:0016021=GO_REF:0000037, GO:0005923=GO_REF:0000024, GO:0008366=GO_REF:0000019, GO:0042802=GO_REF:0000024} O75508 Claudin-11 protein 20050322 {GO:0016338=ISS, GO:0005886=IEA, GO:0005198=IEA, GO:0007283=IEA, GO:0016021=IEA, GO:0005923=ISS, GO:0008366=IEA, GO:0042802=ISS} axon ensheathment, calcium-independent cell-cell adhesion, spermatogenesis integral to membrane, plasma membrane, tight junction identical protein binding, structural molecule activity Human UniProtKB:O88551 CLDN12 Reactome UniProtKB {GO:0016338=GO_REF:0000024, GO:0070830=Reactome:REACT_19373, GO:0005886=GO_REF:0000039, GO:0005198=GO_REF:0000002, GO:0034329=Reactome:REACT_20676, GO:0016021=GO_REF:0000037, GO:0005923=GO_REF:0000024, GO:0045216=Reactome:REACT_19331, GO:0042802=GO_REF:0000024, GO:0071944=GO_REF:0000019} P56749 Claudin-12 protein 20130228 {GO:0016338=ISS, GO:0070830=TAS, GO:0005886=IEA, GO:0005198=IEA, GO:0034329=TAS, GO:0016021=IEA, GO:0005923=ISS, GO:0045216=TAS, GO:0042802=ISS, GO:0071944=IEA} calcium-independent cell-cell adhesion, cell junction assembly, cell-cell junction organization, tight junction assembly cell periphery, integral to membrane, plasma membrane, tight junction identical protein binding, structural molecule activity Human CLDN15 Reactome UniProtKB {GO:0016338=GO_REF:0000024, GO:0070830=Reactome:REACT_19373, GO:0005886=GO_REF:0000039, GO:0005198=GO_REF:0000002, GO:0034329=Reactome:REACT_20676, GO:0016021=GO_REF:0000037, GO:0005923=GO_REF:0000024, GO:0045216=Reactome:REACT_19331, GO:0042802=GO_REF:0000024} P56746 Claudin-15 protein 20130228 {GO:0016338=ISS, GO:0070830=TAS, GO:0005886=IEA, GO:0005198=IEA, GO:0034329=TAS, GO:0016021=IEA, GO:0005923=ISS, GO:0045216=TAS, GO:0042802=ISS} calcium-independent cell-cell adhesion, cell junction assembly, cell-cell junction organization, tight junction assembly integral to membrane, plasma membrane, tight junction identical protein binding, structural molecule activity Human CLDN16 GOC UniProtKB {GO:0007588=PMID:10390358, GO:0015693=PMID:10390358, GO:0016338=GO_REF:0000024, GO:0005886=GO_REF:0000039, GO:0016020=GO_REF:0000002, GO:0005198=GO_REF:0000002, GO:0015095=PMID:10390358, GO:0006875=PMID:10390358, GO:0016021=GO_REF:0000037, GO:0005923=GO_REF:0000024, GO:0042802=GO_REF:0000024} Q9Y5I7 Claudin-16 protein 20130413 {GO:0007588=TAS, GO:0015693=TAS, GO:0016338=ISS, GO:0005886=IEA, GO:0016020=IEA, GO:0005198=IEA, GO:0015095=TAS, GO:0006875=TAS, GO:0016021=IEA, GO:0005923=ISS, GO:0042802=ISS} calcium-independent cell-cell adhesion, cellular metal ion homeostasis, excretion, magnesium ion transport integral to membrane, membrane, plasma membrane, tight junction identical protein binding, magnesium ion transmembrane transporter activity, structural molecule activity Human CLDN17 Reactome UniProtKB {GO:0016338=GO_REF:0000024, GO:0005794=PMID:16780588, GO:0070830=Reactome:REACT_19373, GO:0005886=PMID:16780588, GO:0005198=GO_REF:0000002, GO:0034329=Reactome:REACT_20676, GO:0005923=GO_REF:0000024, GO:0016021=GO_REF:0000037, GO:0045216=Reactome:REACT_19331, GO:0042802=GO_REF:0000024} P56750 Claudin-17 protein 20130228 {GO:0016338=ISS, GO:0005794=IDA, GO:0070830=TAS, GO:0005886=IDA, GO:0005198=IEA, GO:0034329=TAS, GO:0005923=ISS, GO:0016021=IEA, GO:0045216=TAS, GO:0042802=ISS} calcium-independent cell-cell adhesion, cell junction assembly, cell-cell junction organization, tight junction assembly Golgi apparatus, integral to membrane, plasma membrane, tight junction identical protein binding, structural molecule activity Human CLDN18 Reactome UniProtKB {GO:0016338=GO_REF:0000024, GO:0070830=Reactome:REACT_19373, GO:0005886=GO_REF:0000039, GO:0005198=GO_REF:0000002, GO:0034329=Reactome:REACT_20676, GO:0016021=GO_REF:0000037, GO:0005923=GO_REF:0000024, GO:0045216=Reactome:REACT_19331, GO:0042802=GO_REF:0000024} P56856 Claudin-18 protein 20130228 {GO:0016338=ISS, GO:0070830=TAS, GO:0005886=IEA, GO:0005198=IEA, GO:0034329=TAS, GO:0016021=IEA, GO:0005923=ISS, GO:0045216=TAS, GO:0042802=ISS} calcium-independent cell-cell adhesion, cell junction assembly, cell-cell junction organization, tight junction assembly integral to membrane, plasma membrane, tight junction identical protein binding, structural molecule activity Human CLDN19 MGI UniProtKB {GO:0005634=GO_REF:0000019, GO:0019227=GO_REF:0000019, GO:0042802=GO_REF:0000024, GO:0043297=GO_REF:0000019, GO:0016323=PMID:16427635, GO:0043296=PMID:16427635, GO:0005737=GO_REF:0000019, GO:0016338=GO_REF:0000024, GO:0005198=GO_REF:0000019, GO:0016021=GO_REF:0000037, GO:0005923=PMID:16427635, GO:0007601=GO_REF:0000037, GO:0050896=GO_REF:0000037} Q8N6F1 Claudin-19 protein 20070604 {GO:0005634=IEA, GO:0019227=IEA, GO:0042802=ISS, GO:0043297=IEA, GO:0016323=IDA, GO:0043296=IDA, GO:0005737=IEA, GO:0016338=ISS, GO:0005198=IEA, GO:0016021=IEA, GO:0005923=IDA, GO:0007601=IEA, GO:0050896=IEA} apical junction assembly, calcium-independent cell-cell adhesion, neuronal action potential propagation, response to stimulus, visual perception apical junction complex, basolateral plasma membrane, cytoplasm, integral to membrane, nucleus, tight junction identical protein binding, structural molecule activity Human CLDN2 UniProtKB UniProtKB {GO:0016338=GO_REF:0000024, GO:0005886=GO_REF:0000039, GO:0005198=GO_REF:0000002, GO:0005923=GO_REF:0000024, GO:0016021=GO_REF:0000037, GO:0042802=GO_REF:0000024} P57739 Claudin-2 protein 20050322 {GO:0016338=ISS, GO:0005886=IEA, GO:0005198=IEA, GO:0005923=ISS, GO:0016021=IEA, GO:0042802=ISS} calcium-independent cell-cell adhesion integral to membrane, plasma membrane, tight junction identical protein binding, structural molecule activity Human UniProtKB:O88552 CLDN20 Reactome UniProtKB {GO:0016338=GO_REF:0000024, GO:0070830=Reactome:REACT_19373, GO:0005886=GO_REF:0000039, GO:0005198=GO_REF:0000002, GO:0034329=Reactome:REACT_20676, GO:0005923=GO_REF:0000024, GO:0016021=GO_REF:0000037, GO:0045216=Reactome:REACT_19331, GO:0042802=GO_REF:0000024} P56880 Claudin-20 protein 20130228 {GO:0016338=ISS, GO:0070830=TAS, GO:0005886=IEA, GO:0005198=IEA, GO:0034329=TAS, GO:0005923=ISS, GO:0016021=IEA, GO:0045216=TAS, GO:0042802=ISS} calcium-independent cell-cell adhesion, cell junction assembly, cell-cell junction organization, tight junction assembly integral to membrane, plasma membrane, tight junction identical protein binding, structural molecule activity Human CLDN3 PINC UniProtKB {GO:0001666=PMID:15174142, GO:0016338=GO_REF:0000019, GO:0005887=PMID:9334247, GO:0005198=GO_REF:0000002, GO:0016021=PMID:9441748, GO:0005923=GO_REF:0000039, GO:0004888=PMID:9334247, GO:0042802=GO_REF:0000019} O15551 Claudin-3 protein 20030904 {GO:0001666=IEP, GO:0016338=IEA, GO:0005887=TAS, GO:0005198=IEA, GO:0016021=TAS, GO:0005923=IEA, GO:0004888=TAS, GO:0042802=IEA} calcium-independent cell-cell adhesion, response to hypoxia integral to membrane, integral to plasma membrane, tight junction identical protein binding, structural molecule activity, transmembrane signaling receptor activity Human CLDN4 UniProtKB UniProtKB {GO:0007565=GO_REF:0000019, GO:0005886=PMID:9892664, GO:0016328=GO_REF:0000019, GO:0016327=GO_REF:0000019, GO:0042802=GO_REF:0000024, GO:0016324=GO_REF:0000019, GO:0009925=GO_REF:0000019, GO:0016338=GO_REF:0000024, GO:0005198=GO_REF:0000002, GO:0005887=PMID:9334247, GO:0032570=GO_REF:0000019, GO:0005923=GO_REF:0000024, GO:0004888=PMID:9334247} O14493 Claudin-4 protein 20050322 {GO:0007565=IEA, GO:0005886=TAS, GO:0016328=IEA, GO:0016327=IEA, GO:0042802=ISS, GO:0016324=IEA, GO:0009925=IEA, GO:0016338=ISS, GO:0005198=IEA, GO:0005887=TAS, GO:0032570=IEA, GO:0005923=ISS, GO:0004888=TAS} calcium-independent cell-cell adhesion, female pregnancy, response to progesterone stimulus apical plasma membrane, apicolateral plasma membrane, basal plasma membrane, integral to plasma membrane, lateral plasma membrane, plasma membrane, tight junction identical protein binding, structural molecule activity, transmembrane signaling receptor activity Human UniProtKB:Q9Z0G9 CLDN5 UniProtKB UniProtKB {GO:0043220=GO_REF:0000019, GO:0016338=GO_REF:0000024, GO:0005886=GO_REF:0000039, GO:0005911=PMID:18065521, GO:0005198=GO_REF:0000002, GO:0042552=GO_REF:0000019, GO:0033270=GO_REF:0000019, GO:0005923=GO_REF:0000024, GO:0016021=GO_REF:0000037, GO:0042802=GO_REF:0000024} O00501 Claudin-5 protein 20091030 {GO:0043220=IEA, GO:0016338=ISS, GO:0005886=IEA, GO:0005911=IDA, GO:0005198=IEA, GO:0042552=IEA, GO:0033270=IEA, GO:0005923=ISS, GO:0016021=IEA, GO:0042802=ISS} calcium-independent cell-cell adhesion, myelination Schmidt-Lanterman incisure, cell-cell junction, integral to membrane, paranode region of axon, plasma membrane, tight junction identical protein binding, structural molecule activity Human CLDN6 UniProtKB UniProtKB {GO:0016338=GO_REF:0000024, GO:0005886=GO_REF:0000039, GO:0016020=GO_REF:0000002, GO:0005198=GO_REF:0000002, GO:0016021=GO_REF:0000037, GO:0005923=GO_REF:0000024, GO:0042802=GO_REF:0000024} P56747 Claudin-6 protein 20050322 {GO:0016338=ISS, GO:0005886=IEA, GO:0016020=IEA, GO:0005198=IEA, GO:0016021=IEA, GO:0005923=ISS, GO:0042802=ISS} calcium-independent cell-cell adhesion integral to membrane, membrane, plasma membrane, tight junction identical protein binding, structural molecule activity Human UniProtKB:Q9Z0G9 CLDN7 UniProtKB UniProtKB {GO:0005515=PMID:16054130, GO:0016338=GO_REF:0000024, GO:0005886=GO_REF:0000038, GO:0005198=GO_REF:0000002, GO:0016021=GO_REF:0000037, GO:0005923=GO_REF:0000024, GO:0016328=GO_REF:0000039, GO:0042802=GO_REF:0000024} O95471 Claudin-7 protein 20101004 {GO:0005515=IPI, GO:0016338=ISS, GO:0005886=IEA, GO:0005198=IEA, GO:0016021=IEA, GO:0005923=ISS, GO:0016328=IEA, GO:0042802=ISS} calcium-independent cell-cell adhesion integral to membrane, lateral plasma membrane, plasma membrane, tight junction identical protein binding, protein binding, structural molecule activity Human UniProtKB:P16422 CLDN8 UniProtKB UniProtKB {GO:0016338=GO_REF:0000024, GO:0005886=PMID:16780588, GO:0005783=PMID:16780588, GO:0005198=GO_REF:0000002, GO:0005923=GO_REF:0000024, GO:0016021=GO_REF:0000037, GO:0042802=GO_REF:0000024} P56748 Claudin-8 protein 20050322 {GO:0016338=ISS, GO:0005886=IDA, GO:0005783=IDA, GO:0005198=IEA, GO:0005923=ISS, GO:0016021=IEA, GO:0042802=ISS} calcium-independent cell-cell adhesion endoplasmic reticulum, integral to membrane, plasma membrane, tight junction identical protein binding, structural molecule activity Human UniProtKB:Q9Z0G9 CLDND1 UniProtKB UniProtKB {GO:0016324=GO_REF:0000019, GO:0016021=GO_REF:0000037} Q9NY35 Claudin domain-containing protein 1 protein 20130413 {GO:0016324=IEA, GO:0016021=IEA} apical plasma membrane, integral to membrane Human UniProtKB-KW:KW-0812 CLEC11A HPA UniProtKB {GO:0005813=GO_REF:0000052, GO:0008284=PMID:11920266, GO:0005737=GO_REF:0000039, GO:0030246=PMID:9705843, GO:0005576=PMID:9442024, GO:0008083=PMID:11920266} Q9Y240 C-type lectin domain family 11 member A protein 20110516 {GO:0005813=IDA, GO:0008284=IDA, GO:0005737=IEA, GO:0030246=NAS, GO:0005576=IDA, GO:0008083=IDA} positive regulation of cell proliferation centrosome, cytoplasm, extracellular region carbohydrate binding, growth factor activity Human CLEC16A null null {} null null null null {} null null null CLEC17A UniProtKB UniProtKB {GO:0009986=PMID:19419970, GO:0042806=PMID:19419970, GO:0016021=GO_REF:0000037, GO:0005537=PMID:19419970, GO:0046872=GO_REF:0000037} Q6ZS10 C-type lectin domain family 17, member A protein 20100517 {GO:0009986=IDA, GO:0042806=IDA, GO:0016021=IEA, GO:0005537=IDA, GO:0046872=IEA} cell surface, integral to membrane fucose binding, mannose binding, metal ion binding Human CLEC18C UniProtKB UniProtKB {GO:0030246=GO_REF:0000002, GO:0005576=GO_REF:0000039} Q8NCF0 C-type lectin domain family 18 member C protein 20130413 {GO:0030246=IEA, GO:0005576=IEA} extracellular region carbohydrate binding Human UniProtKB-SubCell:SL-0243 CLEC1A PINC UniProtKB {GO:0005622=PMID:10671229, GO:0005887=PMID:10671229, GO:0030246=GO_REF:0000002, GO:0006952=PMID:10671229, GO:0007166=PMID:10671229, GO:0004888=PMID:10671229} Q8NC01 C-type lectin domain family 1 member A protein 20061106 {GO:0005622=TAS, GO:0005887=TAS, GO:0030246=IEA, GO:0006952=TAS, GO:0007166=TAS, GO:0004888=TAS} cell surface receptor signaling pathway, defense response integral to plasma membrane, intracellular carbohydrate binding, transmembrane signaling receptor activity Human CLEC1B PINC UniProtKB {GO:0005515=PMID:19785988, GO:0005887=GO_REF:0000019, GO:0030246=GO_REF:0000002, GO:0006952=PMID:10671229, GO:0007166=PMID:10671229, GO:0004888=PMID:10671229} Q9P126 C-type lectin domain family 1 member B protein 20030904 {GO:0005515=IPI, GO:0005887=IEA, GO:0030246=IEA, GO:0006952=TAS, GO:0007166=TAS, GO:0004888=TAS} cell surface receptor signaling pathway, defense response integral to plasma membrane carbohydrate binding, protein binding, transmembrane signaling receptor activity Human CLEC2A UniProtKB UniProtKB {GO:0005515=PMID:20194751, GO:0005886=GO_REF:0000039, GO:0042267=PMID:20194751, GO:0030246=GO_REF:0000002, GO:0016021=GO_REF:0000037, GO:0042803=PMID:20194751} Q6UVW9 C-type lectin domain family 2 member A protein 20101217 {GO:0005515=IPI, GO:0005886=IEA, GO:0042267=TAS, GO:0030246=IEA, GO:0016021=IEA, GO:0042803=IDA} natural killer cell mediated cytotoxicity integral to membrane, plasma membrane carbohydrate binding, protein binding, protein homodimerization activity Human CLEC2B PINC UniProtKB {GO:0005887=PMID:9038101, GO:0030246=GO_REF:0000002} Q92478 C-type lectin domain family 2 member B protein 20030904 {GO:0005887=TAS, GO:0030246=IEA} integral to plasma membrane carbohydrate binding Human CLEC2D PINC UniProtKB {GO:0016020=PMID:10541800, GO:0009986=PMID:20843815, GO:0005887=PMID:10541800, GO:0005783=PMID:20843815, GO:0030246=GO_REF:0000002, GO:0007166=PMID:10541800, GO:0004888=PMID:10541800} Q9UHP7 C-type lectin domain family 2 member D protein 20030904 {GO:0016020=TAS, GO:0009986=IDA, GO:0005887=TAS, GO:0005783=IDA, GO:0030246=IEA, GO:0007166=TAS, GO:0004888=TAS} cell surface receptor signaling pathway cell surface, endoplasmic reticulum, integral to plasma membrane, membrane carbohydrate binding, transmembrane signaling receptor activity Human CLEC2L UniProtKB UniProtKB {GO:0030246=GO_REF:0000002, GO:0016021=GO_REF:0000037} P0C7M8 C-type lectin domain family 2 member L protein 20130413 {GO:0030246=IEA, GO:0016021=IEA} integral to membrane carbohydrate binding Human UniProtKB-KW:KW-0812 CLEC3B BHF-UCL UniProtKB {GO:0031012=PMID:22261194, GO:0005737=PMID:7798325, GO:0001501=GO_REF:0000019, GO:0001503=PMID:7798325, GO:0010756=GO_REF:0000024, GO:0005509=PMID:9786936, GO:0030246=GO_REF:0000002, GO:0005576=PMID:14718574, GO:0030282=PMID:7589422, GO:0008201=PMID:10727405, GO:0005615=PMID:7798325, GO:0036143=PMID:9786936} P05452 Tetranectin protein 20120228 {GO:0031012=ISS, GO:0005737=IDA, GO:0001501=IEA, GO:0001503=IEP, GO:0010756=ISS, GO:0005509=IDA, GO:0030246=IEA, GO:0005576=NAS, GO:0030282=IEP, GO:0008201=IDA, GO:0005615=IDA, GO:0036143=IPI} bone mineralization, ossification, positive regulation of plasminogen activation, skeletal system development cytoplasm, extracellular matrix, extracellular region, extracellular space calcium ion binding, carbohydrate binding, heparin binding, kringle domain binding colocalizes_with Human UniProtKB:F1SRC8 CLEC4A PINC UniProtKB {GO:0005887=PMID:10438934, GO:0045087=GO_REF:0000037, GO:0030246=GO_REF:0000002, GO:0007155=PMID:10438934, GO:0007166=PMID:10438934, GO:0004888=PMID:10438934} Q9UMR7 C-type lectin domain family 4 member A protein 20030904 {GO:0005887=TAS, GO:0045087=IEA, GO:0030246=IEA, GO:0007155=TAS, GO:0007166=TAS, GO:0004888=TAS} cell adhesion, cell surface receptor signaling pathway, innate immune response integral to plasma membrane carbohydrate binding, transmembrane signaling receptor activity Human CLEC4C UniProtKB UniProtKB {GO:0045087=GO_REF:0000037, GO:0030246=GO_REF:0000002, GO:0016021=GO_REF:0000037} Q8WTT0 C-type lectin domain family 4 member C protein 20130413 {GO:0045087=IEA, GO:0030246=IEA, GO:0016021=IEA} innate immune response integral to membrane carbohydrate binding Human UniProtKB-KW:KW-0399 CLEC4F UniProtKB UniProtKB {GO:0030246=GO_REF:0000002, GO:0016021=GO_REF:0000037, GO:0006897=GO_REF:0000037} Q8N1N0 C-type lectin domain family 4 member F protein 20130413 {GO:0030246=IEA, GO:0016021=IEA, GO:0006897=IEA} endocytosis integral to membrane carbohydrate binding Human UniProtKB-KW:KW-0812 CLEC4G UniProtKB UniProtKB {GO:0030246=GO_REF:0000002, GO:0016021=GO_REF:0000037} Q6UXB4 C-type lectin domain family 4 member G protein 20130413 {GO:0030246=IEA, GO:0016021=IEA} integral to membrane carbohydrate binding Human UniProtKB-KW:KW-0812 CLEC4M PINC UniProtKB {GO:0019062=PMID:11337487, GO:0009988=PMID:11337487, GO:0046790=PMID:11337487, GO:0005576=GO_REF:0000039, GO:0046795=PMID:11337487, GO:0019079=PMID:11337487, GO:0005537=GO_REF:0000037, GO:0046872=GO_REF:0000037, GO:0006897=GO_REF:0000037, GO:0035556=PMID:11337487, GO:0046968=PMID:11337487, GO:0005737=PMID:11337487, GO:0030369=PMID:11257134, GO:0016020=PMID:11337487, GO:0005887=PMID:10072769, GO:0019882=PMID:11337487, GO:0045087=GO_REF:0000037, GO:0019048=PMID:11337487, GO:0042605=PMID:11337487, GO:0007159=PMID:11337487, GO:0030246=PMID:11337487, GO:0004872=PMID:11257134} Q9H2X3 C-type lectin domain family 4 member M protein 20050308 {GO:0019062=TAS, GO:0009988=TAS, GO:0046790=TAS, GO:0005576=IEA, GO:0046795=TAS, GO:0019079=NAS, GO:0005537=IEA, GO:0046872=IEA, GO:0006897=IEA, GO:0035556=NAS, GO:0046968=NAS, GO:0005737=NAS, GO:0030369=NAS, GO:0016020=TAS, GO:0005887=TAS, GO:0019882=NAS, GO:0045087=IEA, GO:0019048=TAS, GO:0042605=NAS, GO:0007159=NAS, GO:0030246=NAS, GO:0004872=NAS} antigen processing and presentation, cell-cell recognition, endocytosis, innate immune response, intracellular signal transduction, intracellular virion transport, leukocyte cell-cell adhesion, peptide antigen transport, viral attachment to host cell, viral genome replication, virus-host interaction cytoplasm, extracellular region, integral to plasma membrane, membrane ICAM-3 receptor activity, carbohydrate binding, mannose binding, metal ion binding, peptide antigen binding, receptor activity, virion binding Human CLEC5A GOC UniProtKB {GO:0043066=GO_REF:0000024, GO:0009986=GO_REF:0000024, GO:0005886=Reactome:REACT_147800, GO:0050715=GO_REF:0000019, GO:0009615=PMID:18496526, GO:0007165=PMID:10449773, GO:0006968=PMID:10449773, GO:0002076=GO_REF:0000024, GO:0001618=PMID:18496526, GO:0005887=PMID:10449773, GO:0019048=GO_REF:0000037, GO:0045087=Reactome:REACT_6802, GO:0030246=GO_REF:0000002} Q9NY25 C-type lectin domain family 5 member A protein 20130413 {GO:0043066=ISS, GO:0009986=ISS, GO:0005886=TAS, GO:0050715=IEA, GO:0009615=IDA, GO:0007165=TAS, GO:0006968=TAS, GO:0002076=ISS, GO:0001618=IDA, GO:0005887=TAS, GO:0019048=IEA, GO:0045087=TAS, GO:0030246=IEA} cellular defense response, innate immune response, negative regulation of apoptotic process, osteoblast development, positive regulation of cytokine secretion, response to virus, signal transduction, virus-host interaction cell surface, integral to plasma membrane, plasma membrane carbohydrate binding, viral receptor activity Human CLEC7A GOC UniProtKB {GO:0042287=PMID:11567029, GO:0008037=PMID:11567029, GO:0005886=GO_REF:0000039, GO:0042832=PMID:11567029, GO:0006910=PMID:11567029, GO:0046872=GO_REF:0000037, GO:0002221=PMID:11567029, GO:0042110=PMID:11567029, GO:0005737=GO_REF:0000039, GO:0009756=PMID:11567029, GO:0006954=GO_REF:0000037, GO:0045087=GO_REF:0000037, GO:0030246=PMID:11567029, GO:0016021=PMID:11567029, GO:0008329=PMID:11567029} Q9BXN2 C-type lectin domain family 7 member A protein 20130413 {GO:0042287=NAS, GO:0008037=IDA, GO:0005886=IEA, GO:0042832=NAS, GO:0006910=IDA, GO:0046872=IEA, GO:0002221=IDA, GO:0042110=TAS, GO:0005737=IEA, GO:0009756=TAS, GO:0006954=IEA, GO:0045087=IEA, GO:0030246=IDA, GO:0016021=TAS, GO:0008329=IDA} T cell activation, carbohydrate mediated signaling, cell recognition, defense response to protozoan, inflammatory response, innate immune response, pattern recognition receptor signaling pathway, phagocytosis, recognition cytoplasm, integral to membrane, plasma membrane MHC protein binding, carbohydrate binding, metal ion binding, pattern recognition receptor activity Human CLGN PINC UniProtKB {GO:0007338=PMID:9177349, GO:0006461=GO_REF:0000019, GO:0005783=PMID:9177349, GO:0006457=GO_REF:0000002, GO:0005509=GO_REF:0000002, GO:0005789=GO_REF:0000039, GO:0016021=GO_REF:0000037, GO:0005635=GO_REF:0000019, GO:0051082=GO_REF:0000002, GO:0007339=GO_REF:0000019} O14967 Calmegin protein 20030904 {GO:0007338=TAS, GO:0006461=IEA, GO:0005783=TAS, GO:0006457=IEA, GO:0005509=IEA, GO:0005789=IEA, GO:0016021=IEA, GO:0005635=IEA, GO:0051082=IEA, GO:0007339=IEA} binding of sperm to zona pellucida, protein complex assembly, protein folding, single fertilization endoplasmic reticulum, endoplasmic reticulum membrane, integral to membrane, nuclear envelope calcium ion binding, unfolded protein binding Human CLIC1 BHF-UCL UniProtKB {GO:0005515=PMID:12681486, GO:0006821=PMID:9139710, GO:0048471=PMID:12681486, GO:0031965=GO_REF:0000039, GO:0005886=GO_REF:0000039, GO:0005247=GO_REF:0000002, GO:0034707=GO_REF:0000037, GO:0051881=GO_REF:0000019, GO:0005634=PMID:16130169, GO:0005635=PMID:9139710, GO:0005254=PMID:9139710, GO:0045669=GO_REF:0000019, GO:0005903=PMID:10793131, GO:0005739=GO_REF:0000019, GO:0007165=PMID:16130169, GO:0005737=PMID:10793131} O00299 Chloride intracellular channel protein 1 protein 20130215 {GO:0005515=IPI, GO:0006821=IDA, GO:0048471=IDA, GO:0031965=IEA, GO:0005886=IEA, GO:0005247=IEA, GO:0034707=IEA, GO:0051881=IEA, GO:0005634=TAS, GO:0005635=IDA, GO:0005254=IDA, GO:0045669=IEA, GO:0005903=TAS, GO:0005739=IEA, GO:0007165=TAS, GO:0005737=IDA} chloride transport, positive regulation of osteoblast differentiation, regulation of mitochondrial membrane potential, signal transduction brush border, chloride channel complex, cytoplasm, mitochondrion, nuclear envelope, nuclear membrane, nucleus, perinuclear region of cytoplasm, plasma membrane chloride channel activity, protein binding, voltage-gated chloride channel activity Human CLIC2 BHF-UCL UniProtKB {GO:0005515=PMID:12681486, GO:0005247=GO_REF:0000002, GO:0034707=GO_REF:0000037, GO:0051099=PMID:15916532, GO:0010881=PMID:15147738, GO:0005634=PMID:16130169, GO:0004364=PMID:15147738, GO:0005254=PMID:9339381, GO:0005622=GO_REF:0000054, GO:0004602=PMID:15147738, GO:0007165=PMID:16130169, GO:0005737=PMID:15916532, GO:0010880=PMID:15916532, GO:0060315=PMID:15916532, GO:0006810=PMID:9339381} O15247 Chloride intracellular channel protein 2 protein 20130215 {GO:0005515=IPI, GO:0005247=IEA, GO:0034707=IEA, GO:0051099=IDA, GO:0010881=IC, GO:0005634=TAS, GO:0004364=IDA, GO:0005254=TAS, GO:0005622=IDA, GO:0004602=IDA, GO:0007165=TAS, GO:0005737=IDA, GO:0010880=IDA, GO:0060315=IDA, GO:0006810=TAS} negative regulation of ryanodine-sensitive calcium-release channel activity, positive regulation of binding, regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion, regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum, signal transduction, transport chloride channel complex, cytoplasm, intracellular, nucleus chloride channel activity, glutathione peroxidase activity, glutathione transferase activity, protein binding, voltage-gated chloride channel activity Human UniProtKB:P0DI81 CLIC3 HPA UniProtKB {GO:0005515=PMID:9880541, GO:0007165=PMID:9880541, GO:0006821=PMID:9880541, GO:0005737=PMID:9880541, GO:0016020=GO_REF:0000002, GO:0005247=GO_REF:0000002, GO:0034707=GO_REF:0000037, GO:0005634=GO_REF:0000052, GO:0005254=PMID:9880541} Q5SQ17 Chloride intracellular channel protein 3 protein 20080205 {GO:0005515=IPI, GO:0007165=TAS, GO:0006821=IMP, GO:0005737=IDA, GO:0016020=IEA, GO:0005247=IEA, GO:0034707=IEA, GO:0005634=IDA, GO:0005254=IMP} chloride transport, signal transduction chloride channel complex, cytoplasm, membrane, nucleus chloride channel activity, protein binding, voltage-gated chloride channel activity Human CLIC4 HPA UniProtKB {GO:0005515=PMID:12163479, GO:0006821=PMID:10793131, GO:0048471=PMID:14569596, GO:0005886=PMID:19776349, GO:0035088=PMID:14569596, GO:0061299=GO_REF:0000019, GO:0015629=PMID:12163372, GO:0005254=PMID:9295337, GO:0030154=PMID:12163372, GO:0016363=PMID:14569596, GO:0005829=PMID:19776349, GO:0005622=GO_REF:0000054, GO:0005739=PMID:14569596, GO:0005737=GO_REF:0000052, GO:0035264=GO_REF:0000019, GO:0007035=GO_REF:0000019, GO:0005911=PMID:14569596, GO:0015630=PMID:14569596, GO:0071277=PMID:17636002, GO:0030659=GO_REF:0000039, GO:0005773=GO_REF:0000019, GO:0030336=PMID:12163372, GO:0005813=PMID:14569596, GO:0009986=PMID:14569596, GO:0005247=GO_REF:0000002, GO:0034707=GO_REF:0000037, GO:0030496=PMID:14569596, GO:0045177=PMID:14569596, GO:0001525=GO_REF:0000019, GO:0009566=GO_REF:0000019, GO:0005902=PMID:14569596, GO:0051493=PMID:14569596, GO:0030216=PMID:17636002, GO:0001886=GO_REF:0000019, GO:0048754=GO_REF:0000019} Q9Y696 Chloride intracellular channel protein 4 protein 20080818 {GO:0005515=IPI, GO:0006821=NAS, GO:0048471=IDA, GO:0005886=IDA, GO:0035088=NAS, GO:0061299=IEA, GO:0015629=TAS, GO:0005254=TAS, GO:0030154=TAS, GO:0016363=IDA, GO:0005829=IDA, GO:0005622=IDA, GO:0005739=IDA, GO:0005737=IDA, GO:0035264=IEA, GO:0007035=IEA, GO:0005911=IDA, GO:0015630=IDA, GO:0071277=IMP, GO:0030659=IEA, GO:0005773=IEA, GO:0030336=IDA, GO:0005813=IDA, GO:0009986=IDA, GO:0005247=IEA, GO:0034707=IEA, GO:0030496=IDA, GO:0045177=IDA, GO:0001525=IEA, GO:0009566=IEA, GO:0005902=IDA, GO:0051493=NAS, GO:0030216=IMP, GO:0001886=IEA, GO:0048754=IEA} angiogenesis, branching morphogenesis of an epithelial tube, cell differentiation, cellular response to calcium ion, chloride transport, endothelial cell morphogenesis, establishment or maintenance of apical/basal cell polarity, fertilization, keratinocyte differentiation, multicellular organism growth, negative regulation of cell migration, regulation of cytoskeleton organization, retina vasculature morphogenesis in camera-type eye, vacuolar acidification actin cytoskeleton, apical part of cell, cell surface, cell-cell junction, centrosome, chloride channel complex, cytoplasm, cytoplasmic vesicle membrane, cytosol, intracellular, microtubule cytoskeleton, microvillus, midbody, mitochondrion, nuclear matrix, perinuclear region of cytoplasm, plasma membrane, vacuole chloride channel activity, protein binding, voltage-gated chloride channel activity Human CLIC5 PINC UniProtKB {GO:0005515=PMID:10793131, GO:0006821=PMID:10793131, GO:0007565=PMID:10793131, GO:0005794=GO_REF:0000039, GO:0005815=GO_REF:0000039, GO:0005247=GO_REF:0000002, GO:0007605=GO_REF:0000019, GO:0034707=GO_REF:0000037, GO:0002024=GO_REF:0000019, GO:0060088=GO_REF:0000019, GO:0032420=GO_REF:0000019, GO:0015629=PMID:10793131, GO:0008104=GO_REF:0000019, GO:0006810=PMID:10793131, GO:0050885=GO_REF:0000019, GO:0005938=GO_REF:0000039} Q9NZA1 Chloride intracellular channel protein 5 protein 20030904 {GO:0005515=IPI, GO:0006821=IDA, GO:0007565=TAS, GO:0005794=IEA, GO:0005815=IEA, GO:0005247=IEA, GO:0007605=IEA, GO:0034707=IEA, GO:0002024=IEA, GO:0060088=IEA, GO:0032420=IEA, GO:0015629=IDA, GO:0008104=IEA, GO:0006810=NAS, GO:0050885=IEA, GO:0005938=IEA} auditory receptor cell stereocilium organization, chloride transport, diet induced thermogenesis, female pregnancy, neuromuscular process controlling balance, protein localization, sensory perception of sound, transport Golgi apparatus, actin cytoskeleton, cell cortex, chloride channel complex, microtubule organizing center, stereocilium protein binding, voltage-gated chloride channel activity Human CLIC6 UniProtKB UniProtKB {GO:0005737=GO_REF:0000039, GO:0031749=GO_REF:0000019, GO:0005886=GO_REF:0000039, GO:0005247=GO_REF:0000002, GO:0034707=GO_REF:0000037, GO:0008022=GO_REF:0000019, GO:0042803=GO_REF:0000019, GO:0031751=GO_REF:0000019, GO:0031750=GO_REF:0000019} Q96NY7 Chloride intracellular channel protein 6 protein 20130413 {GO:0005737=IEA, GO:0031749=IEA, GO:0005886=IEA, GO:0005247=IEA, GO:0034707=IEA, GO:0008022=IEA, GO:0042803=IEA, GO:0031751=IEA, GO:0031750=IEA} chloride channel complex, cytoplasm, plasma membrane D2 dopamine receptor binding, D3 dopamine receptor binding, D4 dopamine receptor binding, protein C-terminus binding, protein homodimerization activity, voltage-gated chloride channel activity Human UniProtKB-SubCell:SL-0039 CLINT1 BHF-UCL UniProtKB {GO:0005515=PMID:12429846, GO:0048471=GO_REF:0000039, GO:0005794=PMID:10942595, GO:0016020=GO_REF:0000039, GO:0030276=PMID:12429846, GO:0030136=GO_REF:0000039, GO:0006892=Reactome:REACT_11235, GO:0016044=Reactome:REACT_11123, GO:0005829=Reactome:REACT_19237, GO:0008289=GO_REF:0000037, GO:0006897=GO_REF:0000037} Q14677 Clathrin interactor 1 protein 20110126 {GO:0005515=IPI, GO:0048471=IEA, GO:0005794=IDA, GO:0016020=IEA, GO:0030276=IPI, GO:0030136=IEA, GO:0006892=TAS, GO:0016044=TAS, GO:0005829=TAS, GO:0008289=IEA, GO:0006897=IEA} cellular membrane organization, endocytosis, post-Golgi vesicle-mediated transport Golgi apparatus, clathrin-coated vesicle, cytosol, membrane, perinuclear region of cytoplasm clathrin binding, lipid binding, protein binding Human UniProtKB:Q9UJY4 CLIP1 HPA UniProtKB {GO:0005515=PMID:17828275, GO:0008017=PMID:17889670, GO:0005882=PMID:1600942, GO:0000236=Reactome:REACT_682, GO:0005881=GO_REF:0000019, GO:0001578=PMID:17889670, GO:0035371=PMID:12433698, GO:0042803=PMID:15928712, GO:0046872=PMID:15928712, GO:0005829=Reactome:REACT_150414, GO:0044354=PMID:12433698, GO:0005737=GO_REF:0000052, GO:0015631=PMID:17889670, GO:0051010=PMID:12433698, GO:0015630=PMID:17889670, GO:0000087=Reactome:REACT_910, GO:0006810=GO_REF:0000037, GO:0030659=GO_REF:0000039, GO:0031116=PMID:17889670, GO:0005813=PMID:21399614, GO:0005874=GO_REF:0000024, GO:0003676=GO_REF:0000002, GO:0001726=GO_REF:0000039, GO:0007067=PMID:15928712, GO:0000776=PMID:15928712, GO:0008270=PMID:17828275, GO:0000278=Reactome:REACT_152, GO:0000090=Reactome:REACT_1275, GO:0005768=PMID:1356075} P30622 CAP-Gly domain-containing linker protein 1 protein 20111111 {GO:0005515=IPI, GO:0008017=IDA, GO:0005882=TAS, GO:0000236=TAS, GO:0005881=IEA, GO:0001578=IMP, GO:0035371=IDA, GO:0042803=TAS, GO:0046872=NAS, GO:0005829=TAS, GO:0044354=IDA, GO:0005737=IDA, GO:0015631=IDA, GO:0051010=IDA, GO:0015630=IMP, GO:0000087=TAS, GO:0006810=IEA, GO:0030659=IEA, GO:0031116=IMP, GO:0005813=IDA, GO:0005874=ISS, GO:0003676=IEA, GO:0001726=IEA, GO:0007067=TAS, GO:0000776=TAS, GO:0008270=IDA, GO:0000278=TAS, GO:0000090=TAS, GO:0005768=TAS} M phase of mitotic cell cycle, microtubule bundle formation, mitosis, mitotic anaphase, mitotic cell cycle, mitotic prometaphase, positive regulation of microtubule polymerization, transport centrosome, cytoplasm, cytoplasmic microtubule, cytoplasmic vesicle membrane, cytosol, endosome, intermediate filament, kinetochore, macropinosome, microtubule, microtubule cytoskeleton, microtubule plus end, ruffle metal ion binding, microtubule binding, microtubule plus-end binding, nucleic acid binding, protein binding, protein homodimerization activity, tubulin binding, zinc ion binding Human CLIP2 PINC UniProtKB {GO:0005881=GO_REF:0000019, GO:0005875=PMID:9799601} Q9UDT6 CAP-Gly domain-containing linker protein 2 protein 20061106 {GO:0005881=IEA, GO:0005875=TAS} cytoplasmic microtubule, microtubule associated complex Human CLIP3 UniProtKB UniProtKB {GO:0005802=GO_REF:0000024, GO:0008017=PMID:20052288, GO:0031115=PMID:15262990, GO:0043065=PMID:20052288, GO:0005795=GO_REF:0000039, GO:0005886=PMID:19139280, GO:0035594=PMID:20052288, GO:0018230=PMID:15262990, GO:0044091=PMID:11854307, GO:0032588=PMID:15262990, GO:0010828=GO_REF:0000024, GO:0045807=PMID:11854307, GO:0031901=PMID:11854307, GO:0001934=GO_REF:0000024, GO:0045444=GO_REF:0000024, GO:0045121=PMID:15262990, GO:0072321=PMID:20052288, GO:0055038=PMID:11854307, GO:0090004=GO_REF:0000024} Q96DZ5 CAP-Gly domain-containing linker protein 3 protein 20120613 {GO:0005802=ISS, GO:0008017=IMP, GO:0031115=IMP, GO:0043065=IMP, GO:0005795=IEA, GO:0005886=IDA, GO:0035594=IDA, GO:0018230=IMP, GO:0044091=IMP, GO:0032588=IMP, GO:0010828=ISS, GO:0045807=IMP, GO:0031901=IDA, GO:0001934=ISS, GO:0045444=ISS, GO:0045121=IDA, GO:0072321=IMP, GO:0055038=IDA, GO:0090004=ISS} chaperone-mediated protein transport, fat cell differentiation, membrane biogenesis, negative regulation of microtubule polymerization, peptidyl-L-cysteine S-palmitoylation, positive regulation of apoptotic process, positive regulation of endocytosis, positive regulation of establishment of protein localization to plasma membrane, positive regulation of glucose transport, positive regulation of protein phosphorylation Golgi stack, early endosome membrane, membrane raft, plasma membrane, recycling endosome membrane, trans-Golgi network, trans-Golgi network membrane ganglioside binding, microtubule binding Human UniProtKB:B9EHT4 CLIP4 null null {} null null null null {} null null null CLK1 PINC UniProtKB {GO:0005737=GO_REF:0000019, GO:0046777=GO_REF:0000019, GO:0018105=GO_REF:0000019, GO:0008283=PMID:1704889, GO:0004674=PMID:10480872, GO:0018107=GO_REF:0000019, GO:0043484=PMID:19168442, GO:0005634=GO_REF:0000039, GO:0018108=GO_REF:0000019, GO:0004712=GO_REF:0000003, GO:0004715=PMID:1825055, GO:0005524=GO_REF:0000037} P49759 Dual specificity protein kinase CLK1 protein 20030904 {GO:0005737=IEA, GO:0046777=IEA, GO:0018105=IEA, GO:0008283=TAS, GO:0004674=IDA, GO:0018107=IEA, GO:0043484=IMP, GO:0005634=IEA, GO:0018108=IEA, GO:0004712=IEA, GO:0004715=TAS, GO:0005524=IEA} cell proliferation, peptidyl-serine phosphorylation, peptidyl-threonine phosphorylation, peptidyl-tyrosine phosphorylation, protein autophosphorylation, regulation of RNA splicing cytoplasm, nucleus ATP binding, non-membrane spanning protein tyrosine kinase activity, protein serine/threonine kinase activity, protein serine/threonine/tyrosine kinase activity Human CLK2 IntAct UniProtKB {GO:0005515=PMID:21988832, GO:0045721=GO_REF:0000024, GO:0018108=GO_REF:0000019, GO:0005634=PMID:9637771, GO:0005524=GO_REF:0000037, GO:0046777=GO_REF:0000024, GO:0016607=GO_REF:0000039, GO:0004674=PMID:10480872, GO:0010212=PMID:20682768, GO:0004712=GO_REF:0000003, GO:0043484=PMID:9637771, GO:0006468=PMID:9637771, GO:0004713=GO_REF:0000019, GO:0032526=GO_REF:0000019} P49760 Dual specificity protein kinase CLK2 protein 20130415 {GO:0005515=IPI, GO:0045721=ISS, GO:0018108=IEA, GO:0005634=IDA, GO:0005524=IEA, GO:0046777=ISS, GO:0016607=IEA, GO:0004674=IDA, GO:0010212=IMP, GO:0004712=IEA, GO:0043484=IDA, GO:0006468=IDA, GO:0004713=IEA, GO:0032526=IEA} negative regulation of gluconeogenesis, peptidyl-tyrosine phosphorylation, protein autophosphorylation, protein phosphorylation, regulation of RNA splicing, response to ionizing radiation, response to retinoic acid nuclear speck, nucleus ATP binding, protein binding, protein serine/threonine kinase activity, protein serine/threonine/tyrosine kinase activity, protein tyrosine kinase activity Human UniProtKB:P08621 CLK3 HPA UniProtKB {GO:0001669=GO_REF:0000039, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0018108=GO_REF:0000019, GO:0005524=GO_REF:0000037, GO:0004672=GO_REF:0000002, GO:0046777=GO_REF:0000019, GO:0016607=GO_REF:0000039, GO:0004674=GO_REF:0000024, GO:0006468=PMID:9637771, GO:0004712=GO_REF:0000003, GO:0043484=PMID:9637771, GO:0045111=GO_REF:0000052, GO:0004713=GO_REF:0000019} P49761 Dual specificity protein kinase CLK3 protein 20120912 {GO:0001669=IEA, GO:0005730=IDA, GO:0005634=IDA, GO:0018108=IEA, GO:0005524=IEA, GO:0004672=IEA, GO:0046777=IEA, GO:0016607=IEA, GO:0004674=ISS, GO:0006468=IDA, GO:0004712=IEA, GO:0043484=IDA, GO:0045111=IDA, GO:0004713=IEA} peptidyl-tyrosine phosphorylation, protein autophosphorylation, protein phosphorylation, regulation of RNA splicing acrosomal vesicle, intermediate filament cytoskeleton, nuclear speck, nucleolus, nucleus ATP binding, protein kinase activity, protein serine/threonine kinase activity, protein serine/threonine/tyrosine kinase activity, protein tyrosine kinase activity Human CLK4 UniProtKB UniProtKB {GO:0046777=GO_REF:0000019, GO:0004674=GO_REF:0000024, GO:0043484=PMID:19168442, GO:0005634=GO_REF:0000039, GO:0018108=GO_REF:0000019, GO:0004712=GO_REF:0000003, GO:0004713=GO_REF:0000019, GO:0005524=GO_REF:0000037} Q9HAZ1 Dual specificity protein kinase CLK4 protein 20110904 {GO:0046777=IEA, GO:0004674=ISS, GO:0043484=IMP, GO:0005634=IEA, GO:0018108=IEA, GO:0004712=IEA, GO:0004713=IEA, GO:0005524=IEA} peptidyl-tyrosine phosphorylation, protein autophosphorylation, regulation of RNA splicing nucleus ATP binding, protein serine/threonine kinase activity, protein serine/threonine/tyrosine kinase activity, protein tyrosine kinase activity Human UniProtKB:O35493 CLMN ENSEMBL UniProtKB {GO:0005737=GO_REF:0000019, GO:0008285=GO_REF:0000019, GO:0003779=GO_REF:0000037, GO:0016021=GO_REF:0000037, GO:0031175=GO_REF:0000019} Q96JQ2 Calmin protein 20130413 {GO:0005737=IEA, GO:0008285=IEA, GO:0003779=IEA, GO:0016021=IEA, GO:0031175=IEA} negative regulation of cell proliferation, neuron projection development cytoplasm, integral to membrane actin binding Human Ensembl:ENSMUSP00000105563 CLN3 InterPro UniProtKB {GO:0005802=PMID:15240864, GO:0005515=PMID:22261744, GO:0008219=GO_REF:0000037, GO:0016242=GO_REF:0000024, GO:0005765=PMID:9384607, GO:0005764=PMID:10924275, GO:0030163=PMID:10740217, GO:0043524=GO_REF:0000024, GO:0007034=GO_REF:0000033, GO:0006457=PMID:8980123, GO:0047496=PMID:22261744, GO:0016485=GO_REF:0000024, GO:0050885=GO_REF:0000024, GO:0008306=GO_REF:0000024, GO:0006684=PMID:15240864, GO:0005794=PMID:15240864, GO:0005795=PMID:15240864, GO:0043086=GO_REF:0000024, GO:0006898=PMID:15471887, GO:0006681=PMID:15240864, GO:0035235=GO_REF:0000024, GO:0045121=PMID:15240864, GO:0035752=PMID:10924275, GO:0051082=PMID:8980123, GO:0007042=PMID:11722572, GO:0001508=GO_REF:0000024, GO:0015809=PMID:16251196, GO:0007040=GO_REF:0000024, GO:0016044=GO_REF:0000024, GO:0006678=PMID:15240864, GO:0043005=PMID:10332042, GO:0005886=PMID:15240864, GO:0001575=PMID:15240864, GO:0005783=PMID:10191111, GO:0006672=PMID:15240864, GO:0005634=PMID:10191116, GO:0030176=PMID:12706816, GO:0005739=PMID:8980123, GO:0005737=PMID:10191116, GO:0000046=GO_REF:0000024, GO:0042987=PMID:10924275, GO:0006520=GO_REF:0000024, GO:0043066=PMID:15240864, GO:0005776=GO_REF:0000024, GO:0005770=PMID:22261744, GO:0051480=GO_REF:0000024, GO:0016236=PMID:9949212, GO:0008021=PMID:11590129, GO:0045861=GO_REF:0000024, GO:0000139=PMID:10191111, GO:0016020=GO_REF:0000002, GO:0005901=PMID:15240864, GO:0016021=PMID:10191112, GO:0005769=PMID:15240864, GO:0042133=GO_REF:0000024} Q9UBH5 Battenin protein 20130413 {GO:0005802=IDA, GO:0005515=IPI, GO:0008219=IEA, GO:0016242=ISS, GO:0005765=IDA, GO:0005764=IDA, GO:0030163=NAS, GO:0043524=ISS, GO:0007034=IBA, GO:0006457=TAS, GO:0047496=IMP, GO:0016485=ISS, GO:0050885=ISS, GO:0008306=ISS, GO:0006684=IMP, GO:0005794=IDA, GO:0005795=IDA, GO:0043086=ISS, GO:0006898=IMP, GO:0006681=IMP, GO:0035235=ISS, GO:0045121=IDA, GO:0035752=IDA, GO:0051082=TAS, GO:0007042=IMP, GO:0001508=ISS, GO:0015809=IDA, GO:0007040=ISS, GO:0016044=ISS, GO:0006678=IMP, GO:0043005=IDA, GO:0005886=IDA, GO:0001575=IMP, GO:0005783=IDA, GO:0006672=IDA, GO:0005634=IDA, GO:0030176=IDA, GO:0005739=TAS, GO:0005737=IDA, GO:0000046=ISS, GO:0042987=IDA, GO:0006520=ISS, GO:0043066=IMP, GO:0005776=ISS, GO:0005770=IDA, GO:0051480=ISS, GO:0016236=NAS, GO:0008021=IDA, GO:0045861=ISS, GO:0000139=IDA, GO:0016020=IEA, GO:0005901=IDA, GO:0016021=IDA, GO:0005769=IDA, GO:0042133=ISS} amyloid precursor protein catabolic process, arginine transport, associative learning, autophagic vacuole fusion, cell death, cellular amino acid metabolic process, cellular membrane organization, ceramide metabolic process, cytosolic calcium ion homeostasis, galactosylceramide metabolic process, globoside metabolic process, glucosylceramide metabolic process, ionotropic glutamate receptor signaling pathway, lysosomal lumen acidification, lysosomal lumen pH elevation, lysosome organization, macroautophagy, negative regulation of apoptotic process, negative regulation of catalytic activity, negative regulation of macroautophagy, negative regulation of neuron apoptotic process, negative regulation of proteolysis, neuromuscular process controlling balance, neurotransmitter metabolic process, protein catabolic process, protein folding, protein processing, receptor-mediated endocytosis, regulation of action potential, sphingomyelin metabolic process, vacuolar transport, vesicle transport along microtubule Golgi apparatus, Golgi membrane, Golgi stack, autophagic vacuole, caveola, cytoplasm, early endosome, endoplasmic reticulum, integral to endoplasmic reticulum membrane, integral to membrane, late endosome, lysosomal membrane, lysosome, membrane, membrane raft, mitochondrion, neuron projection, nucleus, plasma membrane, synaptic vesicle, trans-Golgi network protein binding, unfolded protein binding Human InterPro:IPR003492 CLN5 UniProtKB UniProtKB {GO:0005515=PMID:12134079, GO:0008219=GO_REF:0000037, GO:0005775=GO_REF:0000019, GO:0048471=PMID:10992246, GO:0070085=PMID:16399764, GO:0005794=PMID:12134079, GO:0005783=PMID:12134079, GO:0042551=PMID:10992246, GO:0005765=PMID:12134079, GO:0005537=PMID:16399764, GO:0005764=PMID:11971870, GO:0030163=PMID:10740217, GO:0007420=PMID:10992246, GO:0007042=PMID:11722572, GO:0016021=PMID:12134079, GO:0007601=GO_REF:0000019, GO:0006465=PMID:20052765, GO:0022008=PMID:10992246} O75503 Ceroid-lipofuscinosis neuronal protein 5 protein 20120628 {GO:0005515=IPI, GO:0008219=IEA, GO:0005775=IEA, GO:0048471=IDA, GO:0070085=IDA, GO:0005794=IDA, GO:0005783=IDA, GO:0042551=NAS, GO:0005765=IDA, GO:0005537=IDA, GO:0005764=IDA, GO:0030163=NAS, GO:0007420=IEP, GO:0007042=IMP, GO:0016021=IDA, GO:0007601=IEA, GO:0006465=IDA, GO:0022008=IEP} brain development, cell death, glycosylation, lysosomal lumen acidification, neurogenesis, neuron maturation, protein catabolic process, signal peptide processing, visual perception Golgi apparatus, endoplasmic reticulum, integral to membrane, lysosomal membrane, lysosome, perinuclear region of cytoplasm, vacuolar lumen mannose binding, protein binding Human CLN6 UniProtKB UniProtKB {GO:0005515=PMID:19235893, GO:0044265=GO_REF:0000019, GO:0008219=GO_REF:0000037, GO:0005783=PMID:15265688, GO:0031987=GO_REF:0000019, GO:0045862=PMID:15010453, GO:0042803=PMID:15010453, GO:0030163=PMID:10740217, GO:0005789=GO_REF:0000039, GO:0001573=PMID:16857350, GO:0005788=PMID:15010453, GO:0016021=PMID:11727201, GO:0007042=PMID:11722572, GO:0030203=PMID:16857350, GO:0007601=GO_REF:0000019, GO:0008203=PMID:16857350} Q9NWW5 Ceroid-lipofuscinosis neuronal protein 6 protein 20120615 {GO:0005515=IPI, GO:0044265=IEA, GO:0008219=IEA, GO:0005783=IDA, GO:0031987=IEA, GO:0045862=IMP, GO:0042803=IDA, GO:0030163=NAS, GO:0005789=IEA, GO:0001573=IMP, GO:0005788=IDA, GO:0016021=NAS, GO:0007042=IMP, GO:0030203=IMP, GO:0007601=IEA, GO:0008203=IMP} cell death, cellular macromolecule catabolic process, cholesterol metabolic process, ganglioside metabolic process, glycosaminoglycan metabolic process, locomotion involved in locomotory behavior, lysosomal lumen acidification, positive regulation of proteolysis, protein catabolic process, visual perception endoplasmic reticulum, endoplasmic reticulum lumen, endoplasmic reticulum membrane, integral to membrane protein binding, protein homodimerization activity Human UniProtKB:Q16555 CLN8 UniProtKB UniProtKB {GO:0008361=GO_REF:0000019, GO:0008219=GO_REF:0000037, GO:0060041=GO_REF:0000019, GO:0005783=PMID:10861296, GO:0006672=PMID:16086686, GO:0045494=GO_REF:0000019, GO:0005739=GO_REF:0000019, GO:0030163=PMID:10740217, GO:0050881=GO_REF:0000019, GO:0033116=GO_REF:0000039, GO:0050884=GO_REF:0000019, GO:0007628=GO_REF:0000019, GO:0050885=GO_REF:0000019, GO:0046513=PMID:12151215, GO:0044257=GO_REF:0000019, GO:0008203=PMID:16086686, GO:0008306=GO_REF:0000019, GO:0008610=PMID:12151215, GO:0043066=GO_REF:0000019, GO:0021523=GO_REF:0000019, GO:0060052=GO_REF:0000019, GO:0005793=PMID:10861296, GO:0051348=GO_REF:0000019, GO:0045861=PMID:12151215, GO:0007399=PMID:10508524, GO:0006869=PMID:12151215, GO:0035176=GO_REF:0000019, GO:0005789=GO_REF:0000039, GO:0007006=GO_REF:0000019, GO:0051935=GO_REF:0000019, GO:0016021=PMID:10861296, GO:0006644=PMID:16086686, GO:0007040=GO_REF:0000019, GO:0001306=GO_REF:0000019} Q9UBY8 Protein CLN8 protein 20060915 {GO:0008361=IEA, GO:0008219=IEA, GO:0060041=IEA, GO:0005783=IDA, GO:0006672=IMP, GO:0045494=IEA, GO:0005739=IEA, GO:0030163=NAS, GO:0050881=IEA, GO:0033116=IEA, GO:0050884=IEA, GO:0007628=IEA, GO:0050885=IEA, GO:0046513=NAS, GO:0044257=IEA, GO:0008203=IMP, GO:0008306=IEA, GO:0008610=NAS, GO:0043066=IEA, GO:0021523=IEA, GO:0060052=IEA, GO:0005793=IDA, GO:0051348=IEA, GO:0045861=NAS, GO:0007399=IMP, GO:0006869=NAS, GO:0035176=IEA, GO:0005789=IEA, GO:0007006=IEA, GO:0051935=IEA, GO:0016021=NAS, GO:0006644=IMP, GO:0007040=IEA, GO:0001306=IEA} L-glutamate uptake involved in synaptic transmission, adult walking behavior, age-dependent response to oxidative stress, associative learning, cell death, cellular protein catabolic process, ceramide biosynthetic process, ceramide metabolic process, cholesterol metabolic process, lipid biosynthetic process, lipid transport, lysosome organization, mitochondrial membrane organization, musculoskeletal movement, negative regulation of apoptotic process, negative regulation of proteolysis, negative regulation of transferase activity, nervous system development, neurofilament cytoskeleton organization, neuromuscular process controlling balance, neuromuscular process controlling posture, phospholipid metabolic process, photoreceptor cell maintenance, protein catabolic process, regulation of cell size, retina development in camera-type eye, social behavior, somatic motor neuron differentiation endoplasmic reticulum, endoplasmic reticulum membrane, endoplasmic reticulum-Golgi intermediate compartment, endoplasmic reticulum-Golgi intermediate compartment membrane, integral to membrane, mitochondrion Human CLNK UniProtKB UniProtKB {GO:0035556=PMID:10744659, GO:0005622=PMID:10744659, GO:0006955=PMID:10744659, GO:0005070=PMID:10744659, GO:0007169=GO_REF:0000019} Q7Z7G1 Cytokine-dependent hematopoietic cell linker protein 20010913 {GO:0035556=IDA, GO:0005622=NAS, GO:0006955=NAS, GO:0005070=NAS, GO:0007169=IEA} immune response, intracellular signal transduction, transmembrane receptor protein tyrosine kinase signaling pathway intracellular SH3/SH2 adaptor activity Human CLNS1A IntAct UniProtKB {GO:0005515=PMID:21988832, GO:0006821=GO_REF:0000002, GO:0010467=Reactome:REACT_71, GO:0005886=PMID:9359436, GO:0016070=Reactome:REACT_21257, GO:0008015=PMID:9359436, GO:0005634=GO_REF:0000039, GO:0034660=Reactome:REACT_11052, GO:0000387=Reactome:REACT_11066, GO:0006884=GO_REF:0000002, GO:0005829=Reactome:REACT_10041, GO:0006810=PMID:7887970, GO:0005856=GO_REF:0000039} P54105 Methylosome subunit pICln protein 20130415 {GO:0005515=IPI, GO:0006821=IEA, GO:0010467=TAS, GO:0005886=TAS, GO:0016070=TAS, GO:0008015=TAS, GO:0005634=IEA, GO:0034660=TAS, GO:0000387=TAS, GO:0006884=IEA, GO:0005829=TAS, GO:0006810=TAS, GO:0005856=IEA} RNA metabolic process, blood circulation, cell volume homeostasis, chloride transport, gene expression, ncRNA metabolic process, spliceosomal snRNP assembly, transport cytoskeleton, cytosol, nucleus, plasma membrane protein binding Human UniProtKB:P62318 CLOCK HPA UniProtKB {GO:0001190=GO_REF:0000024, GO:0003700=GO_REF:0000024, GO:0000982=GO_REF:0000024, GO:0009648=PMID:10198158, GO:0005634=GO_REF:0000052, GO:0005829=Reactome:REACT_118740, GO:0043231=GO_REF:0000052, GO:0005737=GO_REF:0000019, GO:0045944=PMID:9576906, GO:0046983=GO_REF:0000002, GO:0004871=GO_REF:0000002, GO:0004402=GO_REF:0000003, GO:0005667=PMID:9576906, GO:0006355=GO_REF:0000024, GO:0006357=PMID:10198158, GO:0005694=PMID:21659603, GO:0005730=GO_REF:0000052, GO:0070888=PMID:18411297, GO:0000978=PMID:18411297, GO:0003677=GO_REF:0000038, GO:0071479=PMID:21659603, GO:0032922=GO_REF:0000024, GO:0007165=PMID:10198158, GO:0007623=PMID:10198158, GO:0000077=PMID:21659603} O15516 Circadian locomoter output cycles protein kaput protein 20101115 {GO:0001190=ISS, GO:0003700=ISS, GO:0000982=ISS, GO:0009648=TAS, GO:0005634=IDA, GO:0005829=TAS, GO:0043231=IDA, GO:0005737=IEA, GO:0045944=IGI, GO:0046983=IEA, GO:0004871=IEA, GO:0004402=IEA, GO:0005667=IPI, GO:0006355=ISS, GO:0006357=TAS, GO:0005694=IDA, GO:0005730=IDA, GO:0070888=IDA, GO:0000978=IDA, GO:0003677=IEA, GO:0071479=IDA, GO:0032922=ISS, GO:0007165=TAS, GO:0007623=TAS, GO:0000077=IMP} DNA damage checkpoint, cellular response to ionizing radiation, circadian regulation of gene expression, circadian rhythm, photoperiodism, positive regulation of transcription from RNA polymerase II promoter, regulation of transcription from RNA polymerase II promoter, regulation of transcription, DNA-dependent, signal transduction chromosome, cytoplasm, cytosol, intracellular membrane-bounded organelle, nucleolus, nucleus, transcription factor complex DNA binding, E-box binding, RNA polymerase II core promoter proximal region sequence-specific DNA binding, RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity, RNA polymerase II transcription factor binding transcription factor activity involved in positive regulation of transcription, histone acetyltransferase activity, protein dimerization activity, sequence-specific DNA binding transcription factor activity, signal transducer activity Human CLP1 Reactome UniProtKB {GO:0008380=Reactome:REACT_1735, GO:0006388=PMID:17495927, GO:0030423=PMID:17495927, GO:0010467=Reactome:REACT_71, GO:0006369=Reactome:REACT_894, GO:0006366=Reactome:REACT_1366, GO:0031124=Reactome:REACT_1849, GO:0000214=PMID:17495927, GO:0005524=PMID:8896421, GO:0035087=PMID:17495927, GO:0046404=GO_REF:0000003, GO:0000398=Reactome:REACT_467, GO:0005654=Reactome:REACT_1935, GO:0051736=PMID:17495927, GO:0051733=PMID:17495927} Q92989 Polyribonucleotide 5'-hydroxyl-kinase Clp1 protein 20130213 {GO:0008380=TAS, GO:0006388=IDA, GO:0030423=IMP, GO:0010467=TAS, GO:0006369=TAS, GO:0006366=TAS, GO:0031124=TAS, GO:0000214=IDA, GO:0005524=TAS, GO:0035087=IDA, GO:0046404=IEA, GO:0000398=TAS, GO:0005654=TAS, GO:0051736=IDA, GO:0051733=IDA} RNA splicing, gene expression, mRNA 3'-end processing, mRNA splicing, via spliceosome, siRNA loading onto RISC involved in RNA interference, tRNA splicing, via endonucleolytic cleavage and ligation, targeting of mRNA for destruction involved in RNA interference, termination of RNA polymerase II transcription, transcription from RNA polymerase II promoter nucleoplasm, tRNA-intron endonuclease complex ATP binding, ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity, ATP-dependent polyribonucleotide 5'-hydroxyl-kinase activity, polydeoxyribonucleotide kinase activity Human CLPB UniProtKB UniProtKB {GO:0034605=PMID:2745427, GO:0005739=GO_REF:0000019, GO:0003674=GO_REF:0000015, GO:0017111=GO_REF:0000002, GO:0005575=GO_REF:0000015, GO:0005524=GO_REF:0000037} Q9H078 Caseinolytic peptidase B protein homolog protein 20081219 {GO:0034605=IDA, GO:0005739=IEA, GO:0003674=ND, GO:0017111=IEA, GO:0005575=ND, GO:0005524=IEA} cellular response to heat cellular_component, mitochondrion ATP binding, molecular_function, nucleoside-triphosphatase activity Human CLPP HPA UniProtKB {GO:0005739=GO_REF:0000052, GO:0005515=PMID:16115876, GO:0004252=GO_REF:0000002, GO:0005759=GO_REF:0000039, GO:0006508=GO_REF:0000037, GO:0008233=PMID:8543061, GO:0005524=GO_REF:0000037} Q16740 Putative ATP-dependent Clp protease proteolytic subunit, mitochondrial protein 20080205 {GO:0005739=IDA, GO:0005515=IPI, GO:0004252=IEA, GO:0005759=IEA, GO:0006508=IEA, GO:0008233=TAS, GO:0005524=IEA} proteolysis mitochondrial matrix, mitochondrion ATP binding, peptidase activity, protein binding, serine-type endopeptidase activity Human CLPS Reactome UniProtKB {GO:0006629=Reactome:REACT_602, GO:0016042=GO_REF:0000037, GO:0007603=Reactome:REACT_160125, GO:0044241=Reactome:REACT_9518, GO:0005576=Reactome:REACT_25240, GO:0044281=Reactome:REACT_111217, GO:0008047=GO_REF:0000002, GO:0001523=Reactome:REACT_24968} P04118 Colipase protein 20070202 {GO:0006629=TAS, GO:0016042=IEA, GO:0007603=TAS, GO:0044241=TAS, GO:0005576=TAS, GO:0044281=TAS, GO:0008047=IEA, GO:0001523=TAS} lipid catabolic process, lipid digestion, lipid metabolic process, phototransduction, visible light, retinoid metabolic process, small molecule metabolic process extracellular region enzyme activator activity Human CLPTM1 BHF-UCL UniProtKB {GO:0005515=PMID:21903422, GO:0005887=PMID:9828125, GO:0033081=GO_REF:0000024, GO:0007275=GO_REF:0000037, GO:0016021=GO_REF:0000038, GO:0030154=GO_REF:0000037, GO:0009897=GO_REF:0000024} O96005 Cleft lip and palate transmembrane protein 1 protein 20071212 {GO:0005515=IPI, GO:0005887=TAS, GO:0033081=ISS, GO:0007275=IEA, GO:0016021=IEA, GO:0030154=IEA, GO:0009897=ISS} cell differentiation, multicellular organismal development, regulation of T cell differentiation in thymus external side of plasma membrane, integral to membrane, integral to plasma membrane protein binding Human UniProtKB:Q8VBZ3 CLPTM1L UniProtKB UniProtKB {GO:0006915=GO_REF:0000037, GO:0016021=GO_REF:0000037} Q96KA5 Cleft lip and palate transmembrane protein 1-like protein protein 20130413 {GO:0006915=IEA, GO:0016021=IEA} apoptotic process integral to membrane Human UniProtKB-KW:KW-0812 CLPX GOC UniProtKB {GO:0042645=PMID:18063578, GO:0005515=PMID:11923310, GO:0005743=GO_REF:0000024, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0005524=GO_REF:0000024, GO:0046872=GO_REF:0000037, GO:0005739=GO_REF:0000052, GO:0016504=PMID:16115876, GO:0010952=PMID:16115876, GO:0006457=GO_REF:0000002, GO:0009841=PMID:16115876, GO:0051603=PMID:16115876, GO:0004176=PMID:16115876, GO:0051082=GO_REF:0000002, GO:0016887=GO_REF:0000024} O76031 ATP-dependent Clp protease ATP-binding subunit clpX-like, mitochondrial protein 20130413 {GO:0042645=IDA, GO:0005515=IPI, GO:0005743=ISS, GO:0005730=IDA, GO:0005634=IDA, GO:0005524=ISS, GO:0046872=IEA, GO:0005739=IDA, GO:0016504=IDA, GO:0010952=IDA, GO:0006457=IEA, GO:0009841=IDA, GO:0051603=IDA, GO:0004176=IDA, GO:0051082=IEA, GO:0016887=ISS} positive regulation of peptidase activity, protein folding, proteolysis involved in cellular protein catabolic process mitochondrial endopeptidase Clp complex, mitochondrial inner membrane, mitochondrial nucleoid, mitochondrion, nucleolus, nucleus ATP binding, ATP-dependent peptidase activity, ATPase activity, metal ion binding, peptidase activator activity, protein binding, unfolded protein binding Human CLSPN IntAct UniProtKB {GO:0005515=PMID:18662541, GO:0010997=PMID:18662541, GO:0031572=PMID:18662541, GO:0006915=Reactome:REACT_578, GO:0003677=GO_REF:0000037, GO:0006921=Reactome:REACT_995, GO:0032147=PMID:16885022, GO:0006260=Reactome:REACT_6769, GO:0006281=GO_REF:0000037, GO:0018105=PMID:16885022, GO:0000075=Reactome:REACT_1538, GO:0005654=Reactome:REACT_13652, GO:0000077=PMID:16963448, GO:0033314=PMID:16885022} Q9HAW4 Claspin protein 20130415 {GO:0005515=IPI, GO:0010997=IPI, GO:0031572=IDA, GO:0006915=TAS, GO:0003677=IEA, GO:0006921=TAS, GO:0032147=IDA, GO:0006260=TAS, GO:0006281=IEA, GO:0018105=IDA, GO:0000075=TAS, GO:0005654=TAS, GO:0000077=IMP, GO:0033314=IMP} DNA damage checkpoint, DNA repair, DNA replication, G2 DNA damage checkpoint, activation of protein kinase activity, apoptotic process, cell cycle checkpoint, cellular component disassembly involved in execution phase of apoptosis, mitotic DNA replication checkpoint, peptidyl-serine phosphorylation nucleoplasm DNA binding, anaphase-promoting complex binding, protein binding Human UniProtKB:Q9UM11 CLSTN1 UniProtKB UniProtKB {GO:0030054=GO_REF:0000037, GO:0000139=GO_REF:0000039, GO:0005886=GO_REF:0000037, GO:0045211=GO_REF:0000039, GO:0005509=GO_REF:0000002, GO:0005789=GO_REF:0000039, GO:0005634=GO_REF:0000039, GO:0005576=GO_REF:0000019, GO:0042995=GO_REF:0000039, GO:0016021=GO_REF:0000038, GO:0007156=GO_REF:0000002} Q5SR54 Calsyntenin-1 protein 20130413 {GO:0030054=IEA, GO:0000139=IEA, GO:0005886=IEA, GO:0045211=IEA, GO:0005509=IEA, GO:0005789=IEA, GO:0005634=IEA, GO:0005576=IEA, GO:0042995=IEA, GO:0016021=IEA, GO:0007156=IEA} homophilic cell adhesion Golgi membrane, cell junction, cell projection, endoplasmic reticulum membrane, extracellular region, integral to membrane, nucleus, plasma membrane, postsynaptic membrane calcium ion binding Human UniProtKB-KW:KW-0812 CLSTN3 UniProtKB UniProtKB {GO:0005886=GO_REF:0000039, GO:0000139=GO_REF:0000039, GO:0045211=GO_REF:0000019, GO:0005509=GO_REF:0000002, GO:0005789=GO_REF:0000039, GO:0016021=GO_REF:0000037, GO:0007156=GO_REF:0000002} Q9BQT9 Calsyntenin-3 protein 20130413 {GO:0005886=IEA, GO:0000139=IEA, GO:0045211=IEA, GO:0005509=IEA, GO:0005789=IEA, GO:0016021=IEA, GO:0007156=IEA} homophilic cell adhesion Golgi membrane, endoplasmic reticulum membrane, integral to membrane, plasma membrane, postsynaptic membrane calcium ion binding Human UniProtKB-SubCell:SL-0039 CLTA BHF-UCL UniProtKB {GO:0042277=GO_REF:0000019, GO:0048011=Reactome:REACT_11061, GO:0030132=GO_REF:0000002, GO:0005886=Reactome:REACT_120835, GO:0042059=Reactome:REACT_12484, GO:0006892=Reactome:REACT_11235, GO:0032588=Reactome:REACT_121003, GO:0006886=GO_REF:0000029, GO:0006897=GO_REF:0000019, GO:0030118=PMID:3267234, GO:0005829=Reactome:REACT_121003, GO:0019886=Reactome:REACT_121399, GO:0003674=GO_REF:0000015, GO:0007173=Reactome:REACT_9417, GO:0007411=Reactome:REACT_18266, GO:0005198=GO_REF:0000002, GO:0016023=GO_REF:0000024, GO:0030130=GO_REF:0000002, GO:0016192=GO_REF:0000002, GO:0030669=Reactome:REACT_121177, GO:0016044=Reactome:REACT_11123} P09496 Clathrin light chain A protein 20120517 {GO:0042277=IEA, GO:0048011=TAS, GO:0030132=IEA, GO:0005886=TAS, GO:0042059=TAS, GO:0006892=TAS, GO:0032588=TAS, GO:0006886=NAS, GO:0006897=IEA, GO:0030118=NAS, GO:0005829=TAS, GO:0019886=TAS, GO:0003674=ND, GO:0007173=TAS, GO:0007411=TAS, GO:0005198=IEA, GO:0016023=ISS, GO:0030130=IEA, GO:0016192=IEA, GO:0030669=TAS, GO:0016044=TAS} antigen processing and presentation of exogenous peptide antigen via MHC class II, axon guidance, cellular membrane organization, endocytosis, epidermal growth factor receptor signaling pathway, intracellular protein transport, negative regulation of epidermal growth factor receptor signaling pathway, neurotrophin TRK receptor signaling pathway, post-Golgi vesicle-mediated transport, vesicle-mediated transport clathrin coat, clathrin coat of coated pit, clathrin coat of trans-Golgi network vesicle, clathrin-coated endocytic vesicle membrane, cytoplasmic membrane-bounded vesicle, cytosol, plasma membrane, trans-Golgi network membrane molecular_function, peptide binding, structural molecule activity Human UniProtKB:O08585 CLTB UniProtKB UniProtKB {GO:0005515=PMID:15533940, GO:0005802=GO_REF:0000019, GO:0042277=GO_REF:0000019, GO:0060170=GO_REF:0000019, GO:0030132=GO_REF:0000002, GO:0005198=GO_REF:0000002, GO:0030130=GO_REF:0000002, GO:0016192=GO_REF:0000002, GO:0006886=GO_REF:0000029, GO:0030118=GO_REF:0000024} P09497 Clathrin light chain B protein 20091109 {GO:0005515=IPI, GO:0005802=IEA, GO:0042277=IEA, GO:0060170=IEA, GO:0030132=IEA, GO:0005198=IEA, GO:0030130=IEA, GO:0016192=IEA, GO:0006886=NAS, GO:0030118=ISS} intracellular protein transport, vesicle-mediated transport cilium membrane, clathrin coat, clathrin coat of coated pit, clathrin coat of trans-Golgi network vesicle, trans-Golgi network peptide binding, protein binding, structural molecule activity Human UniProtKB:P08082 CLTC BHF-UCL UniProtKB {GO:0005515=PMID:12429846, GO:0042470=GO_REF:0000039, GO:0030132=GO_REF:0000002, GO:0030136=PMID:19478182, GO:0006892=Reactome:REACT_11235, GO:0005819=PMID:15858577, GO:0032588=Reactome:REACT_121003, GO:0006886=PMID:1765375, GO:0006898=PMID:15858577, GO:0005829=Reactome:REACT_121003, GO:0030118=PMID:1765375, GO:0031623=PMID:14985334, GO:0005739=GO_REF:0000019, GO:0033572=PMID:14985334, GO:0019886=Reactome:REACT_121399, GO:0007067=PMID:15858577, GO:0005198=PMID:1765375, GO:0030130=GO_REF:0000002, GO:0016192=GO_REF:0000002, GO:0030669=Reactome:REACT_121177, GO:0016044=Reactome:REACT_11123} Q00610 Clathrin heavy chain 1 protein 20100203 {GO:0005515=IPI, GO:0042470=IEA, GO:0030132=IEA, GO:0030136=IDA, GO:0006892=TAS, GO:0005819=IDA, GO:0032588=TAS, GO:0006886=NAS, GO:0006898=IMP, GO:0005829=TAS, GO:0030118=NAS, GO:0031623=IMP, GO:0005739=IEA, GO:0033572=IMP, GO:0019886=TAS, GO:0007067=IMP, GO:0005198=NAS, GO:0030130=IEA, GO:0016192=IEA, GO:0030669=TAS, GO:0016044=TAS} antigen processing and presentation of exogenous peptide antigen via MHC class II, cellular membrane organization, intracellular protein transport, mitosis, post-Golgi vesicle-mediated transport, receptor internalization, receptor-mediated endocytosis, transferrin transport, vesicle-mediated transport clathrin coat, clathrin coat of coated pit, clathrin coat of trans-Golgi network vesicle, clathrin-coated endocytic vesicle membrane, clathrin-coated vesicle, cytosol, melanosome, mitochondrion, spindle, trans-Golgi network membrane protein binding, structural molecule activity Human CLTCL1 GOC UniProtKB {GO:0005802=PMID:19509056, GO:0005515=PMID:19478182, GO:0030132=GO_REF:0000002, GO:0030135=PMID:19509056, GO:0030136=PMID:19478182, GO:0005819=PMID:19509056, GO:0009653=PMID:8733128, GO:0006886=GO_REF:0000002, GO:0006898=PMID:19509056, GO:0007165=PMID:8844170, GO:0005905=PMID:19509056, GO:0007067=PMID:19509056, GO:0005198=GO_REF:0000002, GO:0046326=PMID:19478182, GO:0030130=GO_REF:0000002, GO:0004871=PMID:8844170, GO:0016192=GO_REF:0000002} P53675 Clathrin heavy chain 2 protein 20130413 {GO:0005802=IDA, GO:0005515=IPI, GO:0030132=IEA, GO:0030135=IDA, GO:0030136=IDA, GO:0005819=IDA, GO:0009653=TAS, GO:0006886=IEA, GO:0006898=IDA, GO:0007165=TAS, GO:0005905=IDA, GO:0007067=IDA, GO:0005198=IEA, GO:0046326=IMP, GO:0030130=IEA, GO:0004871=TAS, GO:0016192=IEA} anatomical structure morphogenesis, intracellular protein transport, mitosis, positive regulation of glucose import, receptor-mediated endocytosis, signal transduction, vesicle-mediated transport clathrin coat of coated pit, clathrin coat of trans-Golgi network vesicle, clathrin-coated vesicle, coated pit, coated vesicle, spindle, trans-Golgi network protein binding, signal transducer activity, structural molecule activity Human CLU BHF-UCL UniProtKB {GO:0005515=PMID:16113678, GO:0006629=PMID:2387851, GO:0008219=GO_REF:0000002, GO:0048471=PMID:20068069, GO:0005783=GO_REF:0000039, GO:0032436=PMID:20068069, GO:0001836=PMID:16113678, GO:0005634=GO_REF:0000039, GO:0005615=PMID:19996109, GO:0005829=GO_REF:0000039, GO:0005739=PMID:16113678, GO:0051787=PMID:19996109, GO:0051788=PMID:19996109, GO:0006956=PMID:1585460, GO:0051092=PMID:20068069, GO:0006958=GO_REF:0000037, GO:0031093=Reactome:REACT_21351, GO:0016887=PMID:11123922, GO:0031625=PMID:20068069, GO:0032463=PMID:16113678, GO:0043066=PMID:16113678, GO:0031966=GO_REF:0000039, GO:0043691=PMID:16682745, GO:0034366=PMID:16682745, GO:0050821=PMID:11123922, GO:0030168=Reactome:REACT_798, GO:0005576=Reactome:REACT_21351, GO:0009615=PMID:16548883, GO:2000060=PMID:20068069, GO:0061077=PMID:11123922, GO:0042583=GO_REF:0000039, GO:0007596=Reactome:REACT_604, GO:0045087=GO_REF:0000037, GO:0002576=Reactome:REACT_318} P10909 Clusterin protein 20100113 {GO:0005515=IPI, GO:0006629=NAS, GO:0008219=IEA, GO:0048471=IDA, GO:0005783=IEA, GO:0032436=IMP, GO:0001836=IC, GO:0005634=IEA, GO:0005615=IDA, GO:0005829=IEA, GO:0005739=IDA, GO:0051787=IPI, GO:0051788=IDA, GO:0006956=TAS, GO:0051092=IMP, GO:0006958=IEA, GO:0031093=TAS, GO:0016887=IDA, GO:0031625=IDA, GO:0032463=IMP, GO:0043066=IMP, GO:0031966=IEA, GO:0043691=TAS, GO:0034366=IDA, GO:0050821=IDA, GO:0030168=TAS, GO:0005576=TAS, GO:0009615=IEP, GO:2000060=IMP, GO:0061077=IDA, GO:0042583=IEA, GO:0007596=TAS, GO:0045087=IEA, GO:0002576=TAS} blood coagulation, cell death, chaperone-mediated protein folding, complement activation, complement activation, classical pathway, innate immune response, lipid metabolic process, negative regulation of apoptotic process, negative regulation of protein homooligomerization, platelet activation, platelet degranulation, positive regulation of NF-kappaB transcription factor activity, positive regulation of proteasomal ubiquitin-dependent protein catabolic process, positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process, protein stabilization, release of cytochrome c from mitochondria, response to misfolded protein, response to virus, reverse cholesterol transport chromaffin granule, cytosol, endoplasmic reticulum, extracellular region, extracellular space, mitochondrial membrane, mitochondrion, nucleus, perinuclear region of cytoplasm, platelet alpha granule lumen, spherical high-density lipoprotein particle ATPase activity, misfolded protein binding, protein binding, ubiquitin protein ligase binding Human CLUAP1 IntAct UniProtKB {GO:0005515=PMID:16189514, GO:0005929=GO_REF:0000039, GO:0030030=GO_REF:0000037, GO:0005634=GO_REF:0000039} Q96AJ1 Clusterin-associated protein 1 protein 20130415 {GO:0005515=IPI, GO:0005929=IEA, GO:0030030=IEA, GO:0005634=IEA} cell projection organization cilium, nucleus protein binding Human UniProtKB:P43364 CLYBL UniProtKB UniProtKB {GO:0005739=GO_REF:0000039, GO:0006725=GO_REF:0000002, GO:0008815=GO_REF:0000002, GO:0016830=GO_REF:0000002, GO:0003824=GO_REF:0000002, GO:0046872=GO_REF:0000037, GO:0009346=GO_REF:0000002} Q8N0X4 Citrate lyase subunit beta-like protein, mitochondrial protein 20130413 {GO:0005739=IEA, GO:0006725=IEA, GO:0008815=IEA, GO:0016830=IEA, GO:0003824=IEA, GO:0046872=IEA, GO:0009346=IEA} cellular aromatic compound metabolic process citrate lyase complex, mitochondrion carbon-carbon lyase activity, catalytic activity, citrate (pro-3S)-lyase activity, metal ion binding Human UniProtKB-SubCell:SL-0173 CMA1 ENSEMBL UniProtKB {GO:0042277=GO_REF:0000019, GO:0004252=GO_REF:0000019, GO:0002003=Reactome:REACT_147707, GO:0050727=PMID:1919436, GO:0005576=GO_REF:0000019, GO:0045766=GO_REF:0000019, GO:0050720=PMID:1919436, GO:0005622=GO_REF:0000019, GO:0022617=Reactome:REACT_118572, GO:0030198=Reactome:REACT_118779, GO:0006508=GO_REF:0000019, GO:0008236=PMID:2071582, GO:0030901=GO_REF:0000019, GO:0071333=GO_REF:0000019, GO:0044267=Reactome:REACT_17015, GO:0006518=GO_REF:0000019} Q3SY37 Chymase protein 20130413 {GO:0042277=IEA, GO:0004252=IEA, GO:0002003=TAS, GO:0050727=IC, GO:0005576=IEA, GO:0045766=IEA, GO:0050720=IDA, GO:0005622=IEA, GO:0022617=TAS, GO:0030198=TAS, GO:0006508=IEA, GO:0008236=TAS, GO:0030901=IEA, GO:0071333=IEA, GO:0044267=TAS, GO:0006518=IEA} angiotensin maturation, cellular protein metabolic process, cellular response to glucose stimulus, extracellular matrix disassembly, extracellular matrix organization, interleukin-1 beta biosynthetic process, midbrain development, peptide metabolic process, positive regulation of angiogenesis, proteolysis, regulation of inflammatory response extracellular region, intracellular peptide binding, serine-type endopeptidase activity, serine-type peptidase activity Human Ensembl:ENSRNOP00000061330 CMAS UniPathway UniProtKB {GO:0006054=GO_REF:0000041, GO:0008781=GO_REF:0000003, GO:0005634=GO_REF:0000039, GO:0009103=GO_REF:0000002} Q8NFW8 N-acylneuraminate cytidylyltransferase protein 20130413 {GO:0006054=IEA, GO:0008781=IEA, GO:0005634=IEA, GO:0009103=IEA} N-acetylneuraminate metabolic process, lipopolysaccharide biosynthetic process nucleus N-acylneuraminate cytidylyltransferase activity Human UniPathway:UPA00628 CMBL UniProtKB UniProtKB {GO:0016787=GO_REF:0000037, GO:0005829=GO_REF:0000039} Q96DG6 Carboxymethylenebutenolidase homolog protein 20130413 {GO:0016787=IEA, GO:0005829=IEA} cytosol hydrolase activity Human UniProtKB-SubCell:SL-0091 CMIP UniProtKB UniProtKB {GO:0005737=GO_REF:0000039, GO:0005543=GO_REF:0000002, GO:0005634=GO_REF:0000039} Q8IY22 C-Maf-inducing protein protein 20130413 {GO:0005737=IEA, GO:0005543=IEA, GO:0005634=IEA} cytoplasm, nucleus phospholipid binding Human UniProtKB-SubCell:SL-0086 CMKLR1 GOC UniProtKB {GO:0005515=PMID:14530373, GO:0050848=PMID:14530373, GO:0070098=PMID:9425281, GO:0005886=PMID:14530373, GO:0004930=PMID:9603476, GO:0032088=PMID:15753205, GO:0006955=PMID:9425281, GO:0001501=PMID:9144535, GO:0006935=PMID:14530373, GO:0007186=PMID:14530373, GO:0005887=PMID:9425281, GO:0032695=GO_REF:0000024, GO:0004950=GO_REF:0000002, GO:0010759=PMID:19443732, GO:0004872=PMID:9144535, GO:0016021=PMID:9603476} Q99788 Chemokine-like receptor 1 protein 20130413 {GO:0005515=IPI, GO:0050848=IDA, GO:0070098=TAS, GO:0005886=IDA, GO:0004930=NAS, GO:0032088=IDA, GO:0006955=TAS, GO:0001501=TAS, GO:0006935=IDA, GO:0007186=IDA, GO:0005887=TAS, GO:0032695=ISS, GO:0004950=IEA, GO:0010759=IMP, GO:0004872=TAS, GO:0016021=NAS} G-protein coupled receptor signaling pathway, chemokine-mediated signaling pathway, chemotaxis, immune response, negative regulation of NF-kappaB transcription factor activity, negative regulation of interleukin-12 production, positive regulation of macrophage chemotaxis, regulation of calcium-mediated signaling, skeletal system development integral to membrane, integral to plasma membrane, plasma membrane G-protein coupled receptor activity, chemokine receptor activity, protein binding, receptor activity Human CMPK1 InterPro UniProtKB {GO:0006240=GO_REF:0000019, GO:0015949=Reactome:REACT_21330, GO:0018963=GO_REF:0000019, GO:0004127=GO_REF:0000003, GO:0004849=PMID:10462544, GO:0046705=GO_REF:0000019, GO:0006222=PMID:10462544, GO:0009220=PMID:10462544, GO:0055086=Reactome:REACT_1698, GO:0005634=GO_REF:0000039, GO:0044281=Reactome:REACT_111217, GO:0006227=GO_REF:0000019, GO:0005524=GO_REF:0000002, GO:0006225=GO_REF:0000019, GO:0005829=Reactome:REACT_1618, GO:0019205=GO_REF:0000002, GO:0005737=PMID:10462544, GO:0006139=GO_REF:0000002, GO:0022602=GO_REF:0000019, GO:0033862=GO_REF:0000019} Q5T0D2 UMP-CMP kinase protein 20130413 {GO:0006240=IEA, GO:0015949=TAS, GO:0018963=IEA, GO:0004127=IEA, GO:0004849=TAS, GO:0046705=IEA, GO:0006222=TAS, GO:0009220=TAS, GO:0055086=TAS, GO:0005634=IEA, GO:0044281=TAS, GO:0006227=IEA, GO:0005524=IEA, GO:0006225=IEA, GO:0005829=TAS, GO:0019205=IEA, GO:0005737=TAS, GO:0006139=IEA, GO:0022602=IEA, GO:0033862=IEA} CDP biosynthetic process, UDP biosynthetic process, UMP biosynthetic process, dCDP biosynthetic process, dUDP biosynthetic process, nucleobase-containing compound metabolic process, nucleobase-containing small molecule interconversion, nucleobase-containing small molecule metabolic process, ovulation cycle process, phthalate metabolic process, pyrimidine ribonucleotide biosynthetic process, small molecule metabolic process cytoplasm, cytosol, nucleus ATP binding, UMP kinase activity, cytidylate kinase activity, nucleobase-containing compound kinase activity, uridine kinase activity Human InterPro:IPR000850 CMPK2 HPA UniProtKB {GO:0005739=GO_REF:0000052, GO:0071222=GO_REF:0000019, GO:0004127=PMID:17999954, GO:0005730=GO_REF:0000052, GO:0033862=PMID:17999954, GO:0005634=GO_REF:0000052, GO:0006233=GO_REF:0000019, GO:0006227=GO_REF:0000019, GO:0005524=GO_REF:0000037, GO:0004798=GO_REF:0000019} Q5EBM0 UMP-CMP kinase 2, mitochondrial protein 20111111 {GO:0005739=IDA, GO:0071222=IEA, GO:0004127=IDA, GO:0005730=IDA, GO:0033862=IDA, GO:0005634=IDA, GO:0006233=IEA, GO:0006227=IEA, GO:0005524=IEA, GO:0004798=IEA} cellular response to lipopolysaccharide, dTDP biosynthetic process, dUDP biosynthetic process mitochondrion, nucleolus, nucleus ATP binding, UMP kinase activity, cytidylate kinase activity, thymidylate kinase activity Human CMTM2 HPA UniProtKB {GO:0006935=GO_REF:0000037, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0016021=GO_REF:0000037, GO:0005615=GO_REF:0000037, GO:0005125=GO_REF:0000037} Q8TAZ6 CKLF-like MARVEL transmembrane domain-containing protein 2 protein 20090616 {GO:0006935=IEA, GO:0005730=IDA, GO:0005634=IDA, GO:0016021=IEA, GO:0005615=IEA, GO:0005125=IEA} chemotaxis extracellular space, integral to membrane, nucleolus, nucleus cytokine activity NOT Human CMTM3 UniProtKB UniProtKB {GO:0006935=GO_REF:0000037, GO:0016020=GO_REF:0000002, GO:0016021=GO_REF:0000037, GO:0005615=GO_REF:0000037, GO:0005125=GO_REF:0000037} Q96MX0 CKLF-like MARVEL transmembrane domain-containing protein 3 protein 20130413 {GO:0006935=IEA, GO:0016020=IEA, GO:0016021=IEA, GO:0005615=IEA, GO:0005125=IEA} chemotaxis extracellular space, integral to membrane, membrane cytokine activity Human UniProtKB-KW:KW-0812 CMTM4 UniProtKB UniProtKB {GO:0006935=GO_REF:0000037, GO:0016021=GO_REF:0000037, GO:0005615=GO_REF:0000037, GO:0005125=GO_REF:0000037} Q8IZR5 CKLF-like MARVEL transmembrane domain-containing protein 4 protein 20130413 {GO:0006935=IEA, GO:0016021=IEA, GO:0005615=IEA, GO:0005125=IEA} chemotaxis extracellular space, integral to membrane cytokine activity Human UniProtKB-KW:KW-0812 CMTM6 UniProtKB UniProtKB {GO:0006935=GO_REF:0000037, GO:0016021=GO_REF:0000037, GO:0005615=GO_REF:0000037, GO:0005125=GO_REF:0000037} Q9NX76 CKLF-like MARVEL transmembrane domain-containing protein 6 protein 20130413 {GO:0006935=IEA, GO:0016021=IEA, GO:0005615=IEA, GO:0005125=IEA} chemotaxis extracellular space, integral to membrane cytokine activity Human UniProtKB-KW:KW-0812 CMTM7 UniProtKB UniProtKB {GO:0006935=GO_REF:0000037, GO:0016021=GO_REF:0000037, GO:0005615=GO_REF:0000037, GO:0005125=GO_REF:0000037} Q96FZ5 CKLF-like MARVEL transmembrane domain-containing protein 7 protein 20130413 {GO:0006935=IEA, GO:0016021=IEA, GO:0005615=IEA, GO:0005125=IEA} chemotaxis extracellular space, integral to membrane cytokine activity Human UniProtKB-KW:KW-0812 CMTM8 UniProtKB UniProtKB {GO:0005737=GO_REF:0000039, GO:0006935=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0016021=GO_REF:0000037, GO:0005615=GO_REF:0000037, GO:0005125=GO_REF:0000037} Q8IZV2 CKLF-like MARVEL transmembrane domain-containing protein 8 protein 20130413 {GO:0005737=IEA, GO:0006935=IEA, GO:0005634=IEA, GO:0016021=IEA, GO:0005615=IEA, GO:0005125=IEA} chemotaxis cytoplasm, extracellular space, integral to membrane, nucleus cytokine activity Human UniProtKB-SubCell:SL-0086 CMYA5 UniProtKB UniProtKB {GO:0048471=GO_REF:0000039, GO:0032513=GO_REF:0000019, GO:0043034=GO_REF:0000019, GO:0014733=GO_REF:0000019, GO:0031430=GO_REF:0000039, GO:0070885=GO_REF:0000019, GO:0042802=GO_REF:0000019} Q8N3K9 Cardiomyopathy-associated protein 5 protein 20130413 {GO:0048471=IEA, GO:0032513=IEA, GO:0043034=IEA, GO:0014733=IEA, GO:0031430=IEA, GO:0070885=IEA, GO:0042802=IEA} negative regulation of calcineurin-NFAT signaling cascade, negative regulation of protein phosphatase type 2B activity, regulation of skeletal muscle adaptation M band, costamere, perinuclear region of cytoplasm identical protein binding Human UniProtKB-SubCell:SL-0198 CNBP PINC UniProtKB {GO:0006695=PMID:2562787, GO:0008284=GO_REF:0000024, GO:0006355=PMID:2562787, GO:0003700=PMID:2562787, GO:0005783=GO_REF:0000024, GO:0005634=GO_REF:0000024, GO:0003676=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037, GO:0005829=GO_REF:0000024, GO:0045944=GO_REF:0000024, GO:0008270=GO_REF:0000002, GO:0045893=GO_REF:0000024} P62633 Cellular nucleic acid-binding protein protein 20061109 {GO:0006695=TAS, GO:0008284=ISS, GO:0006355=TAS, GO:0003700=TAS, GO:0005783=ISS, GO:0005634=ISS, GO:0003676=IEA, GO:0003677=IEA, GO:0006351=IEA, GO:0005829=ISS, GO:0045944=ISS, GO:0008270=IEA, GO:0045893=ISS} cholesterol biosynthetic process, positive regulation of cell proliferation, positive regulation of transcription from RNA polymerase II promoter, positive regulation of transcription, DNA-dependent, regulation of transcription, DNA-dependent, transcription, DNA-dependent cytosol, endoplasmic reticulum, nucleus DNA binding, nucleic acid binding, sequence-specific DNA binding transcription factor activity, zinc ion binding Human CNDP1 UniProtKB UniProtKB {GO:0034701=GO_REF:0000002, GO:0004180=GO_REF:0000037, GO:0006508=GO_REF:0000037, GO:0005576=GO_REF:0000039, GO:0016805=GO_REF:0000002, GO:0046872=GO_REF:0000037, GO:0008237=GO_REF:0000037} Q96KN2 Beta-Ala-His dipeptidase protein 20130413 {GO:0034701=IEA, GO:0004180=IEA, GO:0006508=IEA, GO:0005576=IEA, GO:0016805=IEA, GO:0046872=IEA, GO:0008237=IEA} proteolysis extracellular region carboxypeptidase activity, dipeptidase activity, metal ion binding, metallopeptidase activity, tripeptidase activity Human UniProtKB-SubCell:SL-0243 CNDP2 Reactome UniProtKB {GO:0006805=Reactome:REACT_13433, GO:0034701=GO_REF:0000002, GO:0044281=Reactome:REACT_111217, GO:0016805=GO_REF:0000002, GO:0046872=GO_REF:0000037, GO:0005829=Reactome:REACT_75845, GO:0034641=Reactome:REACT_13, GO:0000096=Reactome:REACT_115639, GO:0006750=Reactome:REACT_6960, GO:0006508=GO_REF:0000019, GO:0004180=Reactome:REACT_75845, GO:0008233=GO_REF:0000019, GO:0008237=GO_REF:0000037} Q96KP4 Cytosolic non-specific dipeptidase protein 20110503 {GO:0006805=TAS, GO:0034701=IEA, GO:0044281=TAS, GO:0016805=IEA, GO:0046872=IEA, GO:0005829=TAS, GO:0034641=TAS, GO:0000096=TAS, GO:0006750=TAS, GO:0006508=IEA, GO:0004180=TAS, GO:0008233=IEA, GO:0008237=IEA} cellular nitrogen compound metabolic process, glutathione biosynthetic process, proteolysis, small molecule metabolic process, sulfur amino acid metabolic process, xenobiotic metabolic process cytosol carboxypeptidase activity, dipeptidase activity, metal ion binding, metallopeptidase activity, peptidase activity, tripeptidase activity Human CNGA1 PINC UniProtKB {GO:0030553=GO_REF:0000037, GO:0005887=PMID:7479749, GO:0042622=GO_REF:0000019, GO:0006810=PMID:7479749, GO:0016021=GO_REF:0000038, GO:0007601=GO_REF:0000037, GO:0005216=GO_REF:0000002, GO:0050896=GO_REF:0000037} P29973 cGMP-gated cation channel alpha-1 protein 20030904 {GO:0030553=IEA, GO:0005887=TAS, GO:0042622=IEA, GO:0006810=TAS, GO:0016021=IEA, GO:0007601=IEA, GO:0005216=IEA, GO:0050896=IEA} response to stimulus, transport, visual perception integral to membrane, integral to plasma membrane, photoreceptor outer segment membrane cGMP binding, ion channel activity Human CNGA2 UniProtKB UniProtKB {GO:0007608=GO_REF:0000029, GO:0005516=GO_REF:0000037, GO:0030552=GO_REF:0000037, GO:0005222=GO_REF:0000029, GO:0050896=GO_REF:0000037, GO:0017071=GO_REF:0000029} Q16280 Cyclic nucleotide-gated olfactory channel protein 20021104 {GO:0007608=NAS, GO:0005516=IEA, GO:0030552=IEA, GO:0005222=NAS, GO:0050896=IEA, GO:0017071=NAS} response to stimulus, sensory perception of smell intracellular cyclic nucleotide activated cation channel complex cAMP binding, calmodulin binding, intracellular cAMP activated cation channel activity Human CNGA3 PINC UniProtKB {GO:0007165=PMID:9517456, GO:0046549=GO_REF:0000019, GO:0005886=GO_REF:0000019, GO:0030553=GO_REF:0000037, GO:0005221=GO_REF:0000019, GO:0006810=PMID:9517456, GO:0016021=GO_REF:0000037, GO:0007601=GO_REF:0000037, GO:0005216=GO_REF:0000002, GO:0015276=PMID:9517456, GO:0001750=GO_REF:0000019} Q16281 Cyclic nucleotide-gated cation channel alpha-3 protein 20030904 {GO:0007165=TAS, GO:0046549=IEA, GO:0005886=IEA, GO:0030553=IEA, GO:0005221=IEA, GO:0006810=TAS, GO:0016021=IEA, GO:0007601=IEA, GO:0005216=IEA, GO:0015276=TAS, GO:0001750=IEA} retinal cone cell development, signal transduction, transport, visual perception integral to membrane, photoreceptor outer segment, plasma membrane cGMP binding, intracellular cyclic nucleotide activated cation channel activity, ion channel activity, ligand-gated ion channel activity Human CNGA4 ENSEMBL UniProtKB {GO:0007608=GO_REF:0000019, GO:0030552=GO_REF:0000037, GO:0016021=GO_REF:0000037, GO:0005216=GO_REF:0000002, GO:0050896=GO_REF:0000037} Q8IV77 Cyclic nucleotide-gated cation channel alpha-4 protein 20130413 {GO:0007608=IEA, GO:0030552=IEA, GO:0016021=IEA, GO:0005216=IEA, GO:0050896=IEA} response to stimulus, sensory perception of smell integral to membrane cAMP binding, ion channel activity Human Ensembl:ENSMUSP00000033187 CNGB1 PINC UniProtKB {GO:0043855=GO_REF:0000019, GO:0007608=GO_REF:0000019, GO:0030552=GO_REF:0000037, GO:0033365=GO_REF:0000019, GO:0016020=GO_REF:0000019, GO:0005222=GO_REF:0000029, GO:0006810=PMID:7682292, GO:0045494=GO_REF:0000019, GO:0007602=GO_REF:0000019, GO:0007601=PMID:7682292, GO:0015276=PMID:7682292, GO:0017071=GO_REF:0000029} Q14028 Cyclic nucleotide-gated cation channel beta-1 protein 20030904 {GO:0043855=IEA, GO:0007608=IEA, GO:0030552=IEA, GO:0033365=IEA, GO:0016020=IEA, GO:0005222=NAS, GO:0006810=TAS, GO:0045494=IEA, GO:0007602=IEA, GO:0007601=TAS, GO:0015276=TAS, GO:0017071=NAS} photoreceptor cell maintenance, phototransduction, protein localization to organelle, sensory perception of smell, transport, visual perception intracellular cyclic nucleotide activated cation channel complex, membrane cAMP binding, cyclic nucleotide-gated ion channel activity, intracellular cAMP activated cation channel activity, ligand-gated ion channel activity Human CNGB3 PINC UniProtKB {GO:0005223=GO_REF:0000019, GO:0007165=PMID:10888875, GO:0030553=GO_REF:0000037, GO:0006810=PMID:10888875, GO:0016021=GO_REF:0000037, GO:0007601=GO_REF:0000037, GO:0001750=GO_REF:0000019} Q9NQW8 Cyclic nucleotide-gated cation channel beta-3 protein 20050308 {GO:0005223=IEA, GO:0007165=NAS, GO:0030553=IEA, GO:0006810=NAS, GO:0016021=IEA, GO:0007601=IEA, GO:0001750=IEA} signal transduction, transport, visual perception integral to membrane, photoreceptor outer segment cGMP binding, intracellular cGMP activated cation channel activity Human CNIH4 LIFEdb UniProtKB {GO:0035556=GO_REF:0000002, GO:0016020=GO_REF:0000002, GO:0005783=GO_REF:0000054, GO:0016021=GO_REF:0000037} Q9P003 Protein cornichon homolog 4 protein 20100607 {GO:0035556=IEA, GO:0016020=IEA, GO:0005783=IDA, GO:0016021=IEA} intracellular signal transduction endoplasmic reticulum, integral to membrane, membrane Human CNKSR1 IntAct UniProtKB {GO:0005515=PMID:15670823, GO:0005543=GO_REF:0000002, GO:0005886=PMID:9814705, GO:0005911=PMID:9814705, GO:0016301=GO_REF:0000038, GO:0007265=PMID:14749388, GO:0007266=PMID:14749388, GO:0030674=PMID:14749388, GO:0005938=PMID:15075335, GO:0007169=PMID:9814705} Q969H4 Connector enhancer of kinase suppressor of ras 1 protein 20130415 {GO:0005515=IPI, GO:0005543=IEA, GO:0005886=TAS, GO:0005911=TAS, GO:0016301=IEA, GO:0007265=IPI, GO:0007266=IPI, GO:0030674=IDA, GO:0005938=IDA, GO:0007169=TAS} Ras protein signal transduction, Rho protein signal transduction, transmembrane receptor protein tyrosine kinase signaling pathway cell cortex, cell-cell junction, plasma membrane kinase activity, phospholipid binding, protein binding, protein binding, bridging Human UniProtKB:P61586 CNKSR2 UniProtKB UniProtKB {GO:0043005=GO_REF:0000019, GO:0005737=GO_REF:0000039, GO:0005543=GO_REF:0000002, GO:0045211=GO_REF:0000019, GO:0043025=GO_REF:0000019, GO:0009966=GO_REF:0000002} Q8WXI2 Connector enhancer of kinase suppressor of ras 2 protein 20130413 {GO:0043005=IEA, GO:0005737=IEA, GO:0005543=IEA, GO:0045211=IEA, GO:0043025=IEA, GO:0009966=IEA} regulation of signal transduction cytoplasm, neuron projection, neuronal cell body, postsynaptic membrane phospholipid binding Human UniProtKB-SubCell:SL-0086 CNKSR3 UniProtKB UniProtKB {GO:0005737=GO_REF:0000002, GO:0016020=GO_REF:0000002, GO:0010765=GO_REF:0000024, GO:0033137=GO_REF:0000024, GO:0070373=GO_REF:0000024, GO:0009966=GO_REF:0000002} Q6P9H4 Connector enhancer of kinase suppressor of ras 3 protein 20100528 {GO:0005737=IEA, GO:0016020=IEA, GO:0010765=ISS, GO:0033137=ISS, GO:0070373=ISS, GO:0009966=IEA} negative regulation of ERK1 and ERK2 cascade, negative regulation of peptidyl-serine phosphorylation, positive regulation of sodium ion transport, regulation of signal transduction cytoplasm, membrane Human UniProtKB:Q8BMA3 CNN1 MGI UniProtKB {GO:0005516=GO_REF:0000037, GO:0031032=GO_REF:0000002, GO:0003779=GO_REF:0000019, GO:0006940=PMID:14550641, GO:0005856=PMID:8616889} P51911 Calponin-1 protein 20100316 {GO:0005516=IEA, GO:0031032=IEA, GO:0003779=IEA, GO:0006940=TAS, GO:0005856=IDA} actomyosin structure organization, regulation of smooth muscle contraction cytoskeleton actin binding, calmodulin binding Human CNN2 PINC UniProtKB {GO:0030097=GO_REF:0000019, GO:0005516=GO_REF:0000037, GO:0030336=GO_REF:0000019, GO:0001725=PMID:16236705, GO:0031032=GO_REF:0000002, GO:0003779=GO_REF:0000037, GO:0010628=GO_REF:0000019, GO:0050765=GO_REF:0000019, GO:0032970=PMID:16236705, GO:0005911=PMID:8889829, GO:0042127=GO_REF:0000019, GO:0007010=PMID:8889829, GO:0042060=GO_REF:0000019, GO:0071260=PMID:16236705, GO:0005856=PMID:8889829} Q99439 Calponin-2 protein 20030904 {GO:0030097=IEA, GO:0005516=IEA, GO:0030336=IEA, GO:0001725=IDA, GO:0031032=IEA, GO:0003779=IEA, GO:0010628=IEA, GO:0050765=IEA, GO:0032970=IDA, GO:0005911=TAS, GO:0042127=IEA, GO:0007010=TAS, GO:0042060=IEA, GO:0071260=IDA, GO:0005856=TAS} actomyosin structure organization, cellular response to mechanical stimulus, cytoskeleton organization, hemopoiesis, negative regulation of cell migration, negative regulation of phagocytosis, positive regulation of gene expression, regulation of actin filament-based process, regulation of cell proliferation, wound healing cell-cell junction, cytoskeleton, stress fiber actin binding, calmodulin binding Human CNN3 UniProtKB UniProtKB {GO:0006939=GO_REF:0000029, GO:0008017=GO_REF:0000019, GO:0030172=GO_REF:0000029, GO:0005516=GO_REF:0000029, GO:0043025=GO_REF:0000019, GO:0014069=GO_REF:0000019, GO:0031032=GO_REF:0000002, GO:0032780=GO_REF:0000019, GO:0003779=GO_REF:0000029, GO:0005575=GO_REF:0000015, GO:0005523=GO_REF:0000029} Q15417 Calponin-3 protein 20061026 {GO:0006939=NAS, GO:0008017=IEA, GO:0030172=NAS, GO:0005516=NAS, GO:0043025=IEA, GO:0014069=IEA, GO:0031032=IEA, GO:0032780=IEA, GO:0003779=NAS, GO:0005575=ND, GO:0005523=NAS} actomyosin structure organization, negative regulation of ATPase activity, smooth muscle contraction cellular_component, neuronal cell body, postsynaptic density actin binding, calmodulin binding, microtubule binding, tropomyosin binding, troponin C binding Human CNNM2 MGI UniProtKB {GO:0016323=PMID:21397062, GO:0015693=GO_REF:0000019, GO:0010960=PMID:21397062, GO:0016021=GO_REF:0000037} Q9H8M5 Metal transporter CNNM2 protein 20120328 {GO:0016323=IMP, GO:0015693=IEA, GO:0010960=IMP, GO:0016021=IEA} magnesium ion homeostasis, magnesium ion transport basolateral plasma membrane, integral to membrane Human CNNM3 IntAct UniProtKB {GO:0005515=PMID:19060904, GO:0005886=GO_REF:0000039, GO:0016021=GO_REF:0000037, GO:0006811=GO_REF:0000037} Q8NE01 Metal transporter CNNM3 protein 20130415 {GO:0005515=IPI, GO:0005886=IEA, GO:0016021=IEA, GO:0006811=IEA} ion transport integral to membrane, plasma membrane protein binding Human UniProtKB:Q99750 CNNM4 UniProtKB UniProtKB {GO:0005886=GO_REF:0000039, GO:0016021=GO_REF:0000037, GO:0031214=GO_REF:0000037, GO:0007601=GO_REF:0000037, GO:0050896=GO_REF:0000037, GO:0006811=GO_REF:0000037} Q6P4Q7 Metal transporter CNNM4 protein 20130413 {GO:0005886=IEA, GO:0016021=IEA, GO:0031214=IEA, GO:0007601=IEA, GO:0050896=IEA, GO:0006811=IEA} biomineral tissue development, ion transport, response to stimulus, visual perception integral to membrane, plasma membrane Human UniProtKB-SubCell:SL-0039 CNOT1 IntAct UniProtKB {GO:0005515=PMID:23232451, GO:0010467=Reactome:REACT_71, GO:0016070=Reactome:REACT_21257, GO:0016071=Reactome:REACT_20605, GO:0030331=PMID:16778766, GO:0060213=PMID:21278420, GO:0000122=PMID:16778766, GO:0042974=PMID:16778766, GO:0006351=GO_REF:0000037, GO:0030014=PMID:19558367, GO:2000036=PMID:22367759, GO:0005829=Reactome:REACT_20651, GO:0004535=PMID:21976065, GO:0010606=PMID:21976065, GO:1900153=PMID:21278420, GO:0048387=PMID:16778766, GO:0000932=GO_REF:0000024, GO:0033147=PMID:16778766, GO:0000289=Reactome:REACT_20514, GO:0000288=Reactome:REACT_20639} A5YKK6 CCR4-NOT transcription complex subunit 1 protein 20130415 {GO:0005515=IPI, GO:0010467=TAS, GO:0016070=TAS, GO:0016071=TAS, GO:0030331=IDA, GO:0060213=IMP, GO:0000122=IDA, GO:0042974=IDA, GO:0006351=IEA, GO:0030014=IDA, GO:2000036=IMP, GO:0005829=TAS, GO:0004535=IDA, GO:0010606=IDA, GO:1900153=IMP, GO:0048387=IDA, GO:0000932=ISS, GO:0033147=IDA, GO:0000289=TAS, GO:0000288=TAS} RNA metabolic process, gene expression, mRNA metabolic process, negative regulation of intracellular estrogen receptor signaling pathway, negative regulation of retinoic acid receptor signaling pathway, negative regulation of transcription from RNA polymerase II promoter, nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay, nuclear-transcribed mRNA poly(A) tail shortening, positive regulation of cytoplasmic mRNA processing body assembly, positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay, positive regulation of nuclear-transcribed mRNA poly(A) tail shortening, regulation of stem cell maintenance, transcription, DNA-dependent CCR4-NOT complex, cytoplasmic mRNA processing body, cytosol estrogen receptor binding, poly(A)-specific ribonuclease activity, protein binding, retinoic acid receptor binding Human UniProtKB:Q9UKZ1 CNOT10 IntAct UniProtKB {GO:0005515=PMID:23232451, GO:0010467=Reactome:REACT_71, GO:0016070=Reactome:REACT_21257, GO:0016071=Reactome:REACT_20605, GO:0000289=Reactome:REACT_20514, GO:0030014=PMID:19558367, GO:0005829=Reactome:REACT_20651, GO:0000288=Reactome:REACT_20639} Q9H9A5 CCR4-NOT transcription complex subunit 10 protein 20130415 {GO:0005515=IPI, GO:0010467=TAS, GO:0016070=TAS, GO:0016071=TAS, GO:0000289=TAS, GO:0030014=IDA, GO:0005829=TAS, GO:0000288=TAS} RNA metabolic process, gene expression, mRNA metabolic process, nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay, nuclear-transcribed mRNA poly(A) tail shortening CCR4-NOT complex, cytosol protein binding Human UniProtKB:Q9UKZ1 CNOT2 IntAct UniProtKB {GO:0005515=PMID:21981923, GO:0010467=Reactome:REACT_71, GO:0006355=GO_REF:0000002, GO:0001104=PMID:10637334, GO:0016070=Reactome:REACT_21257, GO:0006357=PMID:10637334, GO:0016071=Reactome:REACT_20605, GO:0005634=PMID:10637334, GO:0001226=PMID:16712523, GO:0000122=PMID:14707134, GO:0030014=PMID:19558367, GO:2000036=PMID:22367759, GO:0005829=Reactome:REACT_20651, GO:0004535=PMID:21299754, GO:0005737=PMID:21299754, GO:0010606=PMID:21299754, GO:0033147=PMID:16778766, GO:0000289=Reactome:REACT_20514, GO:0000288=Reactome:REACT_20639} Q9NZN8 CCR4-NOT transcription complex subunit 2 protein 20130415 {GO:0005515=IPI, GO:0010467=TAS, GO:0006355=IEA, GO:0001104=TAS, GO:0016070=TAS, GO:0006357=NAS, GO:0016071=TAS, GO:0005634=NAS, GO:0001226=IDA, GO:0000122=IDA, GO:0030014=IDA, GO:2000036=IMP, GO:0005829=TAS, GO:0004535=IMP, GO:0005737=IDA, GO:0010606=IMP, GO:0033147=IMP, GO:0000289=TAS, GO:0000288=TAS} RNA metabolic process, gene expression, mRNA metabolic process, negative regulation of intracellular estrogen receptor signaling pathway, negative regulation of transcription from RNA polymerase II promoter, nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay, nuclear-transcribed mRNA poly(A) tail shortening, positive regulation of cytoplasmic mRNA processing body assembly, regulation of stem cell maintenance, regulation of transcription from RNA polymerase II promoter, regulation of transcription, DNA-dependent CCR4-NOT complex, cytoplasm, cytosol, nucleus RNA polymerase II transcription cofactor activity, RNA polymerase II transcription corepressor binding, poly(A)-specific ribonuclease activity, protein binding Human UniProtKB:Q9HCJ0 CNOT3 HPA UniProtKB {GO:0005515=PMID:10637334, GO:0010467=Reactome:REACT_71, GO:0006355=GO_REF:0000037, GO:0016070=Reactome:REACT_21257, GO:0016071=Reactome:REACT_20605, GO:0005634=GO_REF:0000039, GO:0006351=GO_REF:0000037, GO:0030014=PMID:19558367, GO:2000036=PMID:22367759, GO:0005829=Reactome:REACT_20651, GO:0005737=GO_REF:0000052, GO:0000932=GO_REF:0000024, GO:0000289=Reactome:REACT_20514, GO:0000288=Reactome:REACT_20639} O75175 CCR4-NOT transcription complex subunit 3 protein 20080205 {GO:0005515=IPI, GO:0010467=TAS, GO:0006355=IEA, GO:0016070=TAS, GO:0016071=TAS, GO:0005634=IEA, GO:0006351=IEA, GO:0030014=IDA, GO:2000036=IMP, GO:0005829=TAS, GO:0005737=IDA, GO:0000932=ISS, GO:0000289=TAS, GO:0000288=TAS} RNA metabolic process, gene expression, mRNA metabolic process, nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay, nuclear-transcribed mRNA poly(A) tail shortening, regulation of stem cell maintenance, regulation of transcription, DNA-dependent, transcription, DNA-dependent CCR4-NOT complex, cytoplasm, cytoplasmic mRNA processing body, cytosol, nucleus protein binding Human CNOT4 Reactome UniProtKB {GO:0005515=PMID:15001359, GO:0010467=Reactome:REACT_71, GO:0006355=GO_REF:0000037, GO:0004842=PMID:15001359, GO:0016070=Reactome:REACT_21257, GO:0016071=Reactome:REACT_20605, GO:0003723=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0006351=GO_REF:0000037, GO:0030014=PMID:19558367, GO:0051865=PMID:15001359, GO:0005829=Reactome:REACT_20651, GO:0000166=GO_REF:0000002, GO:0008270=GO_REF:0000002, GO:0000289=Reactome:REACT_20514, GO:0000288=Reactome:REACT_20639} O95628 CCR4-NOT transcription complex subunit 4 protein 20090723 {GO:0005515=IPI, GO:0010467=TAS, GO:0006355=IEA, GO:0004842=IDA, GO:0016070=TAS, GO:0016071=TAS, GO:0003723=IEA, GO:0005634=IEA, GO:0006351=IEA, GO:0030014=IDA, GO:0051865=IDA, GO:0005829=TAS, GO:0000166=IEA, GO:0008270=IEA, GO:0000289=TAS, GO:0000288=TAS} RNA metabolic process, gene expression, mRNA metabolic process, nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay, nuclear-transcribed mRNA poly(A) tail shortening, protein autoubiquitination, regulation of transcription, DNA-dependent, transcription, DNA-dependent CCR4-NOT complex, cytosol, nucleus RNA binding, nucleotide binding, protein binding, ubiquitin-protein ligase activity, zinc ion binding Human CNOT6 IntAct UniProtKB {GO:0005515=PMID:21981923, GO:0010467=Reactome:REACT_71, GO:2000327=PMID:18180299, GO:0006355=GO_REF:0000037, GO:0008284=PMID:21233283, GO:0016070=Reactome:REACT_21257, GO:0016071=Reactome:REACT_20605, GO:0003723=GO_REF:0000037, GO:0004532=PMID:11889047, GO:0043928=PMID:20065043, GO:0005634=GO_REF:0000039, GO:0070966=PMID:15314026, GO:0046872=GO_REF:0000037, GO:0030014=PMID:19558367, GO:0006351=GO_REF:0000037, GO:0005829=Reactome:REACT_20651, GO:0004535=Reactome:REACT_20651, GO:0010606=PMID:21233283, GO:0035195=PMID:20065043, GO:0000289=Reactome:REACT_20514, GO:0000288=Reactome:REACT_20639} Q9ULM6 CCR4-NOT transcription complex subunit 6 protein 20130415 {GO:0005515=IPI, GO:0010467=TAS, GO:2000327=IDA, GO:0006355=IEA, GO:0008284=IMP, GO:0016070=TAS, GO:0016071=TAS, GO:0003723=IEA, GO:0004532=IDA, GO:0043928=IDA, GO:0005634=IEA, GO:0070966=IMP, GO:0046872=IEA, GO:0030014=IDA, GO:0006351=IEA, GO:0005829=TAS, GO:0004535=TAS, GO:0010606=IMP, GO:0035195=TAS, GO:0000289=TAS, GO:0000288=TAS} RNA metabolic process, exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay, gene expression, gene silencing by miRNA, mRNA metabolic process, nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay, nuclear-transcribed mRNA catabolic process, no-go decay, nuclear-transcribed mRNA poly(A) tail shortening, positive regulation of cell proliferation, positive regulation of cytoplasmic mRNA processing body assembly, positive regulation of ligand-dependent nuclear receptor transcription coactivator activity, regulation of transcription, DNA-dependent, transcription, DNA-dependent CCR4-NOT complex, cytosol, nucleus RNA binding, exoribonuclease activity, metal ion binding, poly(A)-specific ribonuclease activity, protein binding Human UniProtKB:Q9HCJ0 CNOT6L Reactome UniProtKB {GO:0010467=Reactome:REACT_71, GO:0008284=PMID:21233283, GO:0016070=Reactome:REACT_21257, GO:0016071=Reactome:REACT_20605, GO:0005634=PMID:21233283, GO:0046872=GO_REF:0000037, GO:0030014=PMID:19558367, GO:0005829=Reactome:REACT_20651, GO:0061157=GO_REF:0000019, GO:0004535=Reactome:REACT_20651, GO:0005737=PMID:21233283, GO:0010606=PMID:21233283, GO:0000289=Reactome:REACT_20514, GO:0000288=Reactome:REACT_20639} Q96LI5 CCR4-NOT transcription complex subunit 6-like protein 20130301 {GO:0010467=TAS, GO:0008284=IMP, GO:0016070=TAS, GO:0016071=TAS, GO:0005634=IDA, GO:0046872=IEA, GO:0030014=IDA, GO:0005829=TAS, GO:0061157=IEA, GO:0004535=TAS, GO:0005737=IDA, GO:0010606=IMP, GO:0000289=TAS, GO:0000288=TAS} RNA metabolic process, gene expression, mRNA destabilization, mRNA metabolic process, nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay, nuclear-transcribed mRNA poly(A) tail shortening, positive regulation of cell proliferation, positive regulation of cytoplasmic mRNA processing body assembly CCR4-NOT complex, cytoplasm, cytosol, nucleus metal ion binding, poly(A)-specific ribonuclease activity Human CNOT7 IntAct UniProtKB {GO:0005515=PMID:22977175, GO:0010467=Reactome:REACT_71, GO:0008284=PMID:19605561, GO:0008285=PMID:19276069, GO:0003700=PMID:9820826, GO:0000290=GO_REF:0000019, GO:0004532=PMID:19276069, GO:0005634=PMID:9820826, GO:0031047=GO_REF:0000024, GO:0030014=PMID:19558367, GO:0005829=Reactome:REACT_20651, GO:0000932=GO_REF:0000024, GO:0045944=GO_REF:0000019, GO:0004871=PMID:9820826, GO:0000289=Reactome:REACT_20514, GO:0000288=Reactome:REACT_20639, GO:0033962=GO_REF:0000019, GO:0016070=Reactome:REACT_21257, GO:0016071=Reactome:REACT_20605, GO:0005975=PMID:9820826, GO:0060213=PMID:21278420, GO:0043928=PMID:20065043, GO:0003676=GO_REF:0000002, GO:0006351=GO_REF:0000037, GO:0004535=PMID:19276069, GO:0007165=PMID:9820826, GO:0000175=PMID:15769875, GO:1900153=PMID:21278420, GO:0035195=PMID:20065043} Q9UIV1 CCR4-NOT transcription complex subunit 7 protein 20130415 {GO:0005515=IPI, GO:0010467=TAS, GO:0008284=IMP, GO:0008285=IDA, GO:0003700=TAS, GO:0000290=IEA, GO:0004532=IDA, GO:0005634=IDA, GO:0031047=ISS, GO:0030014=IDA, GO:0005829=TAS, GO:0000932=ISS, GO:0045944=IEA, GO:0004871=TAS, GO:0000289=TAS, GO:0000288=TAS, GO:0033962=IEA, GO:0016070=TAS, GO:0016071=TAS, GO:0005975=TAS, GO:0060213=IMP, GO:0043928=IDA, GO:0003676=IEA, GO:0006351=IEA, GO:0004535=IDA, GO:0007165=TAS, GO:0000175=IDA, GO:1900153=IMP, GO:0035195=TAS} RNA metabolic process, carbohydrate metabolic process, cytoplasmic mRNA processing body assembly, deadenylation-dependent decapping of nuclear-transcribed mRNA, exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay, gene expression, gene silencing by RNA, gene silencing by miRNA, mRNA metabolic process, negative regulation of cell proliferation, nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay, nuclear-transcribed mRNA poly(A) tail shortening, positive regulation of cell proliferation, positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay, positive regulation of nuclear-transcribed mRNA poly(A) tail shortening, positive regulation of transcription from RNA polymerase II promoter, signal transduction, transcription, DNA-dependent CCR4-NOT complex, cytoplasmic mRNA processing body, cytosol, nucleus 3'-5'-exoribonuclease activity, exoribonuclease activity, nucleic acid binding, poly(A)-specific ribonuclease activity, protein binding, sequence-specific DNA binding transcription factor activity, signal transducer activity Human UniProtKB:A5YKK6 CNOT8 IntAct UniProtKB {GO:0005515=PMID:22977175, GO:0010467=Reactome:REACT_71, GO:0006355=PMID:10036195, GO:0008284=PMID:19605561, GO:0003700=PMID:10036195, GO:0008285=PMID:9820826, GO:0016070=Reactome:REACT_21257, GO:0016071=Reactome:REACT_20605, GO:0043928=PMID:20065043, GO:0005634=PMID:10036195, GO:0003676=GO_REF:0000002, GO:0006351=GO_REF:0000037, GO:0030014=PMID:19558367, GO:0005829=Reactome:REACT_20651, GO:0005622=GO_REF:0000054, GO:0004535=PMID:15769875, GO:0000175=PMID:15769875, GO:0035195=PMID:20065043, GO:0000289=Reactome:REACT_20514, GO:0000288=Reactome:REACT_20639} Q9UFF9 CCR4-NOT transcription complex subunit 8 protein 20130415 {GO:0005515=IPI, GO:0010467=TAS, GO:0006355=NAS, GO:0008284=IMP, GO:0003700=NAS, GO:0008285=TAS, GO:0016070=TAS, GO:0016071=TAS, GO:0043928=IDA, GO:0005634=NAS, GO:0003676=IEA, GO:0006351=IEA, GO:0030014=IDA, GO:0005829=TAS, GO:0005622=IDA, GO:0004535=IDA, GO:0000175=IDA, GO:0035195=TAS, GO:0000289=TAS, GO:0000288=TAS} RNA metabolic process, exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay, gene expression, gene silencing by miRNA, mRNA metabolic process, negative regulation of cell proliferation, nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay, nuclear-transcribed mRNA poly(A) tail shortening, positive regulation of cell proliferation, regulation of transcription, DNA-dependent, transcription, DNA-dependent CCR4-NOT complex, cytosol, intracellular, nucleus 3'-5'-exoribonuclease activity, nucleic acid binding, poly(A)-specific ribonuclease activity, protein binding, sequence-specific DNA binding transcription factor activity Human UniProtKB:A5YKK6 CNP BHF-UCL UniProtKB {GO:0008344=GO_REF:0000019, GO:0048471=GO_REF:0000019, GO:0005886=GO_REF:0000019, GO:0003723=GO_REF:0000037, GO:0005743=GO_REF:0000019, GO:0007268=PMID:1322358, GO:0005741=GO_REF:0000019, GO:0007409=GO_REF:0000019, GO:0005615=PMID:12379507, GO:0031143=GO_REF:0000019, GO:0035749=GO_REF:0000019, GO:0030551=GO_REF:0000019, GO:0005737=PMID:12379507, GO:0032496=GO_REF:0000019, GO:0035748=GO_REF:0000019, GO:0046902=GO_REF:0000019, GO:0042470=GO_REF:0000039, GO:0016070=GO_REF:0000002, GO:0009214=GO_REF:0000002, GO:0004113=GO_REF:0000003, GO:0007568=GO_REF:0000019, GO:0009636=GO_REF:0000019, GO:0000226=GO_REF:0000019, GO:0005902=GO_REF:0000019, GO:0016020=GO_REF:0000002, GO:0030900=GO_REF:0000019} P09543 2',3'-cyclic-nucleotide 3'-phosphodiesterase protein 20080215 {GO:0008344=IEA, GO:0048471=IEA, GO:0005886=IEA, GO:0003723=IEA, GO:0005743=IEA, GO:0007268=TAS, GO:0005741=IEA, GO:0007409=IEA, GO:0005615=IDA, GO:0031143=IEA, GO:0035749=IEA, GO:0030551=IEA, GO:0005737=IDA, GO:0032496=IEA, GO:0035748=IEA, GO:0046902=IEA, GO:0042470=IEA, GO:0016070=IEA, GO:0009214=IEA, GO:0004113=IEA, GO:0007568=IEA, GO:0009636=IEA, GO:0000226=IEA, GO:0005902=IEA, GO:0016020=IEA, GO:0030900=IEA} RNA metabolic process, adult locomotory behavior, aging, axonogenesis, cyclic nucleotide catabolic process, forebrain development, microtubule cytoskeleton organization, regulation of mitochondrial membrane permeability, response to lipopolysaccharide, response to toxic substance, synaptic transmission cytoplasm, extracellular space, melanosome, membrane, microvillus, mitochondrial inner membrane, mitochondrial outer membrane, myelin sheath abaxonal region, myelin sheath adaxonal region, perinuclear region of cytoplasm, plasma membrane, pseudopodium 2',3'-cyclic-nucleotide 3'-phosphodiesterase activity, RNA binding, cyclic nucleotide binding Human CNPPD1 UniProtKB UniProtKB {GO:0019901=GO_REF:0000002, GO:0016021=GO_REF:0000037, GO:0000079=GO_REF:0000002} Q9BV87 Protein CNPPD1 protein 20130413 {GO:0019901=IEA, GO:0016021=IEA, GO:0000079=IEA} regulation of cyclin-dependent protein serine/threonine kinase activity integral to membrane protein kinase binding Human UniProtKB-KW:KW-0812 CNPY2 BHF-UCL UniProtKB {GO:0005515=PMID:12826659, GO:0005887=PMID:10072769, GO:0005783=GO_REF:0000039, GO:0010629=PMID:22378787, GO:0010988=PMID:22378787, GO:0045716=PMID:22378787} Q9Y2B0 Protein canopy homolog 2 protein 20120601 {GO:0005515=IPI, GO:0005887=TAS, GO:0005783=IEA, GO:0010629=ISS, GO:0010988=ISS, GO:0045716=ISS} negative regulation of gene expression, positive regulation of low-density lipoprotein particle receptor biosynthetic process, regulation of low-density lipoprotein particle clearance endoplasmic reticulum, integral to plasma membrane protein binding Human UniProtKB:Q9QXT0 CNPY4 UniProtKB UniProtKB {GO:0005102=GO_REF:0000019, GO:0005576=GO_REF:0000039} Q8N129 Protein canopy homolog 4 protein 20130413 {GO:0005102=IEA, GO:0005576=IEA} extracellular region receptor binding Human UniProtKB-SubCell:SL-0243 CNR1 Reactome UniProtKB {GO:0002866=GO_REF:0000019, GO:0005886=Reactome:REACT_22289, GO:0060405=GO_REF:0000019, GO:0031999=GO_REF:0000019, GO:0045471=GO_REF:0000019, GO:0007283=GO_REF:0000019, GO:0045776=GO_REF:0000019, GO:0042220=GO_REF:0000019, GO:0045777=GO_REF:0000019, GO:0033004=GO_REF:0000019, GO:0045759=GO_REF:0000019, GO:0004949=PMID:18761332, GO:0031622=GO_REF:0000019, GO:0008144=GO_REF:0000019, GO:0032496=GO_REF:0000019, GO:0007610=PMID:1718258, GO:0007613=GO_REF:0000019, GO:0051966=GO_REF:0000019, GO:0060259=GO_REF:0000019, GO:0043065=GO_REF:0000019, GO:0007584=GO_REF:0000019, GO:0060135=GO_REF:0000019, GO:0007568=GO_REF:0000019, GO:0006950=GO_REF:0000019, GO:0043278=GO_REF:0000019, GO:0019233=GO_REF:0000019, GO:0051001=GO_REF:0000019, GO:0050796=GO_REF:0000019, GO:0007187=PMID:1718258, GO:0005887=PMID:1718258, GO:0032228=GO_REF:0000019, GO:0010976=GO_REF:0000019, GO:0007188=PMID:18761332, GO:0016021=GO_REF:0000002, GO:0033602=GO_REF:0000019, GO:0035094=GO_REF:0000019} P21554 Cannabinoid receptor 1 protein 20090430 {GO:0002866=IEA, GO:0005886=TAS, GO:0060405=IEA, GO:0031999=IEA, GO:0045471=IEA, GO:0007283=IEA, GO:0045776=IEA, GO:0042220=IEA, GO:0045777=IEA, GO:0033004=IEA, GO:0045759=IEA, GO:0004949=IDA, GO:0031622=IEA, GO:0008144=IEA, GO:0032496=IEA, GO:0007610=TAS, GO:0007613=IEA, GO:0051966=IEA, GO:0060259=IEA, GO:0043065=IEA, GO:0007584=IEA, GO:0060135=IEA, GO:0007568=IEA, GO:0006950=IEA, GO:0043278=IEA, GO:0019233=IEA, GO:0051001=IEA, GO:0050796=IEA, GO:0007187=TAS, GO:0005887=TAS, GO:0032228=IEA, GO:0010976=IEA, GO:0007188=IDA, GO:0016021=IEA, GO:0033602=IEA, GO:0035094=IEA} G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger, adenylate cyclase-modulating G-protein coupled receptor signaling pathway, aging, behavior, maternal process involved in female pregnancy, memory, negative regulation of action potential, negative regulation of blood pressure, negative regulation of dopamine secretion, negative regulation of fatty acid beta-oxidation, negative regulation of mast cell activation, negative regulation of nitric-oxide synthase activity, positive regulation of acute inflammatory response to antigenic stimulus, positive regulation of apoptotic process, positive regulation of blood pressure, positive regulation of fever generation, positive regulation of neuron projection development, regulation of feeding behavior, regulation of insulin secretion, regulation of penile erection, regulation of synaptic transmission, GABAergic, regulation of synaptic transmission, glutamatergic, response to cocaine, response to ethanol, response to lipopolysaccharide, response to morphine, response to nicotine, response to nutrient, response to stress, sensory perception of pain, spermatogenesis integral to membrane, integral to plasma membrane, plasma membrane cannabinoid receptor activity, drug binding Human CNR2 Reactome UniProtKB {GO:0005886=Reactome:REACT_22289, GO:0033004=GO_REF:0000019, GO:0045759=GO_REF:0000019, GO:0019233=GO_REF:0000019, GO:0030425=GO_REF:0000039, GO:0004949=GO_REF:0000019, GO:0031234=GO_REF:0000019, GO:0006955=PMID:7556170, GO:0001975=GO_REF:0000019, GO:0006954=GO_REF:0000037, GO:0051001=GO_REF:0000019, GO:0007187=PMID:8679694, GO:0005887=PMID:8679694, GO:0050728=GO_REF:0000019, GO:0032496=GO_REF:0000019, GO:0007610=GO_REF:0000019, GO:0032229=GO_REF:0000019, GO:0043204=GO_REF:0000039} P34972 Cannabinoid receptor 2 protein 20090430 {GO:0005886=TAS, GO:0033004=IEA, GO:0045759=IEA, GO:0019233=IEA, GO:0030425=IEA, GO:0004949=IEA, GO:0031234=IEA, GO:0006955=TAS, GO:0001975=IEA, GO:0006954=IEA, GO:0051001=IEA, GO:0007187=TAS, GO:0005887=TAS, GO:0050728=IEA, GO:0032496=IEA, GO:0007610=IEA, GO:0032229=IEA, GO:0043204=IEA} G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger, behavior, immune response, inflammatory response, negative regulation of action potential, negative regulation of inflammatory response, negative regulation of mast cell activation, negative regulation of nitric-oxide synthase activity, negative regulation of synaptic transmission, GABAergic, response to amphetamine, response to lipopolysaccharide, sensory perception of pain dendrite, extrinsic to internal side of plasma membrane, integral to plasma membrane, perikaryon, plasma membrane cannabinoid receptor activity Human CNRIP1 null null {} null null null null {} null null null CNST IntAct UniProtKB {GO:0005515=PMID:22321011, GO:0030133=PMID:19864490, GO:0005802=PMID:19864490, GO:0043234=GO_REF:0000054, GO:0005794=GO_REF:0000039, GO:0005886=PMID:19864490, GO:0019902=PMID:19389623, GO:0010923=PMID:19389623, GO:0042998=PMID:19864490, GO:0016021=GO_REF:0000037, GO:0071253=GO_REF:0000024} Q6PJW8 Consortin protein 20130415 {GO:0005515=IPI, GO:0030133=IDA, GO:0005802=IDA, GO:0043234=IDA, GO:0005794=IEA, GO:0005886=IDA, GO:0019902=IDA, GO:0010923=IDA, GO:0042998=IMP, GO:0016021=IEA, GO:0071253=ISS} negative regulation of phosphatase activity, positive regulation of Golgi to plasma membrane protein transport Golgi apparatus, integral to membrane, plasma membrane, protein complex, trans-Golgi network, transport vesicle connexin binding, phosphatase binding, protein binding Human UniProtKB:P62136 CNTF HPA UniProtKB {GO:0005138=PMID:12643274, GO:0046533=GO_REF:0000019, GO:0008284=GO_REF:0000019, GO:0042517=PMID:12643274, GO:0070120=PMID:12643274, GO:0005615=PMID:12643274, GO:0043231=GO_REF:0000052, GO:0097058=PMID:10966616, GO:0005127=PMID:1714745, GO:0048644=GO_REF:0000019, GO:0007165=PMID:1840538, GO:0043524=PMID:10966616, GO:0005737=GO_REF:0000039, GO:0048666=GO_REF:0000019, GO:0040007=GO_REF:0000002, GO:0008083=PMID:12643274, GO:0046668=GO_REF:0000019} P26441 Ciliary neurotrophic factor protein 20101115 {GO:0005138=IPI, GO:0046533=IEA, GO:0008284=IEA, GO:0042517=IDA, GO:0070120=IDA, GO:0005615=IC, GO:0043231=IDA, GO:0097058=IDA, GO:0005127=TAS, GO:0048644=IEA, GO:0007165=NAS, GO:0043524=IDA, GO:0005737=IEA, GO:0048666=IEA, GO:0040007=IEA, GO:0008083=IDA, GO:0046668=IEA} ciliary neurotrophic factor-mediated signaling pathway, growth, muscle organ morphogenesis, negative regulation of neuron apoptotic process, negative regulation of photoreceptor cell differentiation, neuron development, positive regulation of cell proliferation, positive regulation of tyrosine phosphorylation of Stat3 protein, regulation of retinal cell programmed cell death, signal transduction CRLF-CLCF1 complex, cytoplasm, extracellular space, intracellular membrane-bounded organelle ciliary neurotrophic factor receptor binding, growth factor activity, interleukin-6 receptor binding Human CNTFR ENSEMBL UniProtKB {GO:0008284=GO_REF:0000019, GO:0003360=GO_REF:0000019, GO:0005886=GO_REF:0000039, GO:0097059=PMID:11285233, GO:0005102=PMID:12707266, GO:0031225=GO_REF:0000037, GO:0070120=PMID:12643274, GO:0007399=PMID:7585948, GO:0007165=PMID:1648265, GO:0043524=GO_REF:0000019, GO:0001967=GO_REF:0000019, GO:0019955=PMID:15272019, GO:0016020=GO_REF:0000002, GO:0060538=GO_REF:0000019, GO:0007548=GO_REF:0000019, GO:0004897=GO_REF:0000019, GO:0019898=PMID:1648265} Q5T8H6 Ciliary neurotrophic factor receptor subunit alpha protein 20130413 {GO:0008284=IEA, GO:0003360=IEA, GO:0005886=IEA, GO:0097059=IDA, GO:0005102=IPI, GO:0031225=IEA, GO:0070120=IDA, GO:0007399=TAS, GO:0007165=NAS, GO:0043524=IEA, GO:0001967=IEA, GO:0019955=IPI, GO:0016020=IEA, GO:0060538=IEA, GO:0007548=IEA, GO:0004897=IEA, GO:0019898=TAS} brainstem development, ciliary neurotrophic factor-mediated signaling pathway, negative regulation of neuron apoptotic process, nervous system development, positive regulation of cell proliferation, sex differentiation, signal transduction, skeletal muscle organ development, suckling behavior CNTFR-CLCF1 complex, anchored to membrane, extrinsic to membrane, membrane, plasma membrane ciliary neurotrophic factor receptor activity, cytokine binding, receptor binding Human Ensembl:ENSMUSP00000100026 CNTLN HPA UniProtKB {GO:0005739=GO_REF:0000052, GO:0005813=GO_REF:0000052, GO:0016020=GO_REF:0000002, GO:0005814=GO_REF:0000039, GO:0000155=GO_REF:0000002} Q9NXG0 Centlein protein 20110516 {GO:0005739=IDA, GO:0005813=IDA, GO:0016020=IEA, GO:0005814=IEA, GO:0000155=IEA} centriole, centrosome, membrane, mitochondrion phosphorelay sensor kinase activity Human CNTN1 Reactome UniProtKB {GO:0005886=GO_REF:0000039, GO:0021549=GO_REF:0000019, GO:0031225=GO_REF:0000037, GO:0031175=GO_REF:0000019, GO:0010628=GO_REF:0000019, GO:0001948=GO_REF:0000019, GO:0016020=PMID:7959734, GO:0007219=Reactome:REACT_118859, GO:0010765=GO_REF:0000019, GO:0007411=Reactome:REACT_18266, GO:0010976=GO_REF:0000019, GO:0030246=GO_REF:0000019, GO:0007155=GO_REF:0000037} Q12860 Contactin-1 protein 20100322 {GO:0005886=IEA, GO:0021549=IEA, GO:0031225=IEA, GO:0031175=IEA, GO:0010628=IEA, GO:0001948=IEA, GO:0016020=TAS, GO:0007219=TAS, GO:0010765=IEA, GO:0007411=TAS, GO:0010976=IEA, GO:0030246=IEA, GO:0007155=IEA} Notch signaling pathway, axon guidance, cell adhesion, cerebellum development, neuron projection development, positive regulation of gene expression, positive regulation of neuron projection development, positive regulation of sodium ion transport anchored to membrane, membrane, plasma membrane carbohydrate binding, glycoprotein binding Human CNTN2 BHF-UCL UniProtKB {GO:0005886=GO_REF:0000024, GO:0022010=GO_REF:0000019, GO:0045202=GO_REF:0000024, GO:0031225=GO_REF:0000037, GO:0043621=GO_REF:0000019, GO:0042802=PMID:12963709, GO:0031623=GO_REF:0000019, GO:0007413=GO_REF:0000019, GO:0001948=GO_REF:0000019, GO:0048168=GO_REF:0000019, GO:0007411=Reactome:REACT_18266, GO:0043209=GO_REF:0000024, GO:0008076=GO_REF:0000019, GO:0007628=GO_REF:0000019, GO:0043025=GO_REF:0000019, GO:0060168=GO_REF:0000019, GO:0007612=GO_REF:0000019, GO:0007155=GO_REF:0000037, GO:0009986=GO_REF:0000019, GO:0044224=GO_REF:0000024, GO:0031133=GO_REF:0000019, GO:0000226=GO_REF:0000019, GO:0021853=GO_REF:0000019, GO:0048710=GO_REF:0000019, GO:0033268=GO_REF:0000024, GO:0010954=GO_REF:0000019, GO:0045665=GO_REF:0000019, GO:0045163=GO_REF:0000024, GO:0005887=PMID:8425542, GO:0030246=GO_REF:0000019, GO:0034613=GO_REF:0000024, GO:0001764=GO_REF:0000019, GO:0071206=GO_REF:0000019} Q02246 Contactin-2 protein 20091117 {GO:0005886=ISS, GO:0022010=IEA, GO:0045202=ISS, GO:0031225=IEA, GO:0043621=IEA, GO:0042802=TAS, GO:0031623=IEA, GO:0007413=IEA, GO:0001948=IEA, GO:0048168=IEA, GO:0007411=TAS, GO:0043209=ISS, GO:0008076=IEA, GO:0007628=IEA, GO:0043025=IEA, GO:0060168=IEA, GO:0007612=IEA, GO:0007155=IEA, GO:0009986=IEA, GO:0044224=ISS, GO:0031133=IEA, GO:0000226=IEA, GO:0021853=IEA, GO:0048710=IEA, GO:0033268=ISS, GO:0010954=IEA, GO:0045665=IEA, GO:0045163=ISS, GO:0005887=TAS, GO:0030246=IEA, GO:0034613=ISS, GO:0001764=IEA, GO:0071206=IEA} adult walking behavior, axon guidance, axonal fasciculation, cell adhesion, cellular protein localization, central nervous system myelination, cerebral cortex GABAergic interneuron migration, clustering of voltage-gated potassium channels, establishment of protein localization to juxtaparanode region of axon, learning, microtubule cytoskeleton organization, negative regulation of neuron differentiation, neuron migration, positive regulation of adenosine receptor signaling pathway, positive regulation of protein processing, receptor internalization, regulation of astrocyte differentiation, regulation of axon diameter, regulation of neuronal synaptic plasticity anchored to membrane, cell surface, integral to plasma membrane, juxtaparanode region of axon, myelin sheath, neuronal cell body, node of Ranvier, plasma membrane, synapse, voltage-gated potassium channel complex carbohydrate binding, glycoprotein binding, identical protein binding, protein self-association Human UniProtKB:P22063 CNTN3 UniProtKB UniProtKB {GO:0005886=GO_REF:0000039, GO:0031225=GO_REF:0000037, GO:0007155=GO_REF:0000037, GO:0007399=GO_REF:0000019} Q9P232 Contactin-3 protein 20130413 {GO:0005886=IEA, GO:0031225=IEA, GO:0007155=IEA, GO:0007399=IEA} cell adhesion, nervous system development anchored to membrane, plasma membrane Human UniProtKB-SubCell:SL-0039 CNTN4 UniProtKB UniProtKB {GO:0030424=PMID:14571131, GO:0005886=PMID:15106122, GO:0005576=GO_REF:0000039, GO:0031225=GO_REF:0000037, GO:0007409=PMID:14571131, GO:0031175=GO_REF:0000024, GO:0007399=PMID:15106122, GO:0007413=PMID:15106122, GO:0045665=PMID:14571131, GO:0007420=GO_REF:0000024, GO:0048167=PMID:15106122, GO:0007411=PMID:15106122, GO:0007158=PMID:14571131} Q8IWV2 Contactin-4 protein 20051129 {GO:0030424=NAS, GO:0005886=NAS, GO:0005576=IEA, GO:0031225=IEA, GO:0007409=TAS, GO:0031175=ISS, GO:0007399=IMP, GO:0007413=TAS, GO:0045665=IMP, GO:0007420=ISS, GO:0048167=TAS, GO:0007411=TAS, GO:0007158=TAS} axon guidance, axonal fasciculation, axonogenesis, brain development, negative regulation of neuron differentiation, nervous system development, neuron cell-cell adhesion, neuron projection development, regulation of synaptic plasticity anchored to membrane, axon, extracellular region, plasma membrane Human CNTN5 HPA UniProtKB {GO:0005737=GO_REF:0000052, GO:0005886=GO_REF:0000039, GO:0007605=GO_REF:0000019, GO:0031225=GO_REF:0000037, GO:0007155=GO_REF:0000037} O94779 Contactin-5 protein 20110516 {GO:0005737=IDA, GO:0005886=IEA, GO:0007605=IEA, GO:0031225=IEA, GO:0007155=IEA} cell adhesion, sensory perception of sound anchored to membrane, cytoplasm, plasma membrane Human CNTN6 Reactome UniProtKB {GO:0005886=GO_REF:0000039, GO:0007219=GO_REF:0000037, GO:0007411=Reactome:REACT_18266, GO:0031225=GO_REF:0000037, GO:0007417=PMID:9486763, GO:0007155=GO_REF:0000037} Q9UQ52 Contactin-6 protein 20091012 {GO:0005886=IEA, GO:0007219=IEA, GO:0007411=TAS, GO:0031225=IEA, GO:0007417=TAS, GO:0007155=IEA} Notch signaling pathway, axon guidance, cell adhesion, central nervous system development anchored to membrane, plasma membrane Human CNTNAP1 BHF-UCL UniProtKB {GO:0005515=PMID:17474147, GO:0017124=GO_REF:0000019, GO:0002175=GO_REF:0000024, GO:0030913=GO_REF:0000024, GO:0033270=GO_REF:0000024, GO:0007165=PMID:9118959, GO:0005887=PMID:9118959, GO:0007411=Reactome:REACT_18266, GO:0048812=GO_REF:0000024, GO:0005070=PMID:9118959, GO:0008076=GO_REF:0000024, GO:0007010=GO_REF:0000024, GO:0050884=GO_REF:0000019, GO:0050885=GO_REF:0000019, GO:0004872=PMID:9118959, GO:0008088=GO_REF:0000024, GO:0007155=GO_REF:0000037} P78357 Contactin-associated protein 1 protein 20110818 {GO:0005515=IPI, GO:0017124=IEA, GO:0002175=ISS, GO:0030913=ISS, GO:0033270=ISS, GO:0007165=TAS, GO:0005887=TAS, GO:0007411=TAS, GO:0048812=ISS, GO:0005070=TAS, GO:0008076=ISS, GO:0007010=ISS, GO:0050884=IEA, GO:0050885=IEA, GO:0004872=TAS, GO:0008088=ISS, GO:0007155=IEA} axon cargo transport, axon guidance, cell adhesion, cytoskeleton organization, neuromuscular process controlling balance, neuromuscular process controlling posture, neuron projection morphogenesis, paranodal junction assembly, protein localization to paranode region of axon, signal transduction integral to plasma membrane, paranode region of axon, voltage-gated potassium channel complex SH3 domain binding, SH3/SH2 adaptor activity, protein binding, receptor activity Human UniProtKB:O54991 CNTNAP2 BHF-UCL UniProtKB {GO:0030424=GO_REF:0000024, GO:0021987=PMID:18987363, GO:0008038=PMID:10624965, GO:0019226=PMID:11352571, GO:0031175=GO_REF:0000019, GO:0030425=GO_REF:0000024, GO:0021794=PMID:18179893, GO:0008076=PMID:10624965, GO:0043025=GO_REF:0000024, GO:0043204=GO_REF:0000024, GO:0007610=PMID:18179893, GO:0030673=PMID:19706678, GO:0007155=GO_REF:0000037, GO:0071109=PMID:18179893, GO:0005794=PMID:19166515, GO:0009986=PMID:19706678, GO:0044224=GO_REF:0000024, GO:0071625=PMID:19896112, GO:0021756=PMID:18179893, GO:0016020=PMID:10624965, GO:0007420=PMID:10624965, GO:0045163=GO_REF:0000024, GO:0021761=PMID:18179895, GO:0071205=GO_REF:0000019, GO:0016021=PMID:11352571, GO:0034613=GO_REF:0000024, GO:0019899=PMID:19166515, GO:0005769=PMID:19706678} Q9UHC6 Contactin-associated protein-like 2 protein 20110725 {GO:0030424=ISS, GO:0021987=IEP, GO:0008038=NAS, GO:0019226=NAS, GO:0031175=IEA, GO:0030425=ISS, GO:0021794=IEP, GO:0008076=IDA, GO:0043025=ISS, GO:0043204=ISS, GO:0007610=IMP, GO:0030673=IDA, GO:0007155=IEA, GO:0071109=IEP, GO:0005794=IDA, GO:0009986=IDA, GO:0044224=ISS, GO:0071625=IMP, GO:0021756=IEP, GO:0016020=IDA, GO:0007420=TAS, GO:0045163=ISS, GO:0021761=IEP, GO:0071205=IEA, GO:0016021=NAS, GO:0034613=ISS, GO:0019899=IPI, GO:0005769=IDA} behavior, brain development, cell adhesion, cellular protein localization, cerebral cortex development, clustering of voltage-gated potassium channels, limbic system development, neuron projection development, neuron recognition, protein localization to juxtaparanode region of axon, striatum development, superior temporal gyrus development, thalamus development, transmission of nerve impulse, vocalization behavior Golgi apparatus, axolemma, axon, cell surface, dendrite, early endosome, integral to membrane, juxtaparanode region of axon, membrane, neuronal cell body, perikaryon, voltage-gated potassium channel complex enzyme binding Human CNTNAP3 UniProtKB UniProtKB {GO:0008037=PMID:12093160, GO:0005886=GO_REF:0000039, GO:0005576=GO_REF:0000039, GO:0016021=PMID:12093160, GO:0007155=GO_REF:0000037} Q9BZ76 Contactin-associated protein-like 3 protein 20021104 {GO:0008037=NAS, GO:0005886=IEA, GO:0005576=IEA, GO:0016021=NAS, GO:0007155=IEA} cell adhesion, cell recognition extracellular region, integral to membrane, plasma membrane Human CNTNAP3B UniProtKB UniProtKB {GO:0016021=GO_REF:0000037, GO:0007155=GO_REF:0000037} Q96NU0 Contactin-associated protein-like 3B protein 20130413 {GO:0016021=IEA, GO:0007155=IEA} cell adhesion integral to membrane Human UniProtKB-KW:KW-0812 CNTNAP4 UniProtKB UniProtKB {GO:0016021=GO_REF:0000037, GO:0007155=GO_REF:0000037} Q9C0A0 Contactin-associated protein-like 4 protein 20130413 {GO:0016021=IEA, GO:0007155=IEA} cell adhesion integral to membrane Human UniProtKB-KW:KW-0812 CNTRL Reactome UniProtKB {GO:0005515=PMID:17140400, GO:0005813=PMID:15337773, GO:0000086=Reactome:REACT_2203, GO:0000278=Reactome:REACT_152, GO:0005829=Reactome:REACT_121382, GO:0051301=GO_REF:0000037} Q7Z7A1 Centriolin protein 20121108 {GO:0005515=IPI, GO:0005813=IDA, GO:0000086=TAS, GO:0000278=TAS, GO:0005829=TAS, GO:0051301=IEA} G2/M transition of mitotic cell cycle, cell division, mitotic cell cycle centrosome, cytosol protein binding Human CNTROB HPA UniProtKB {GO:0005515=PMID:16275750, GO:0000910=PMID:16275750, GO:0005737=GO_REF:0000052, GO:0005813=GO_REF:0000052, GO:0007099=PMID:16275750, GO:0005814=PMID:16275750, GO:0051299=PMID:16275750, GO:0019904=PMID:11984006} Q8N137 Centrobin protein 20100326 {GO:0005515=IPI, GO:0000910=IMP, GO:0005737=IDA, GO:0005813=IDA, GO:0007099=IMP, GO:0005814=IDA, GO:0051299=IMP, GO:0019904=IPI} centriole replication, centrosome separation, cytokinesis centriole, centrosome, cytoplasm protein binding, protein domain specific binding Human COA5 ENSEMBL UniProtKB {GO:0005739=GO_REF:0000019} Q86WW8 Cytochrome c oxidase assembly factor 5 protein 20130413 {GO:0005739=IEA} mitochondrion Human Ensembl:ENSMUSP00000027286 COASY HPA UniProtKB {GO:0004595=PMID:11994049, GO:0015939=Reactome:REACT_11172, GO:0005730=GO_REF:0000052, GO:0006767=Reactome:REACT_11238, GO:0015937=PMID:11923312, GO:0005741=Reactome:REACT_11222, GO:0005634=GO_REF:0000052, GO:0005575=GO_REF:0000015, GO:0044281=Reactome:REACT_111217, GO:0005524=GO_REF:0000037, GO:0005737=GO_REF:0000052, GO:0004140=PMID:11923312, GO:0006766=Reactome:REACT_11193, GO:0009108=Reactome:REACT_11218} Q13057 Bifunctional coenzyme A synthase protein 20100326 {GO:0004595=IDA, GO:0015939=TAS, GO:0005730=IDA, GO:0006767=TAS, GO:0015937=IDA, GO:0005741=TAS, GO:0005634=IDA, GO:0005575=ND, GO:0044281=TAS, GO:0005524=IEA, GO:0005737=IDA, GO:0004140=IDA, GO:0006766=TAS, GO:0009108=TAS} coenzyme A biosynthetic process, coenzyme biosynthetic process, pantothenate metabolic process, small molecule metabolic process, vitamin metabolic process, water-soluble vitamin metabolic process cellular_component, cytoplasm, mitochondrial outer membrane, nucleolus, nucleus ATP binding, dephospho-CoA kinase activity, pantetheine-phosphate adenylyltransferase activity Human COBL BHF-UCL UniProtKB {GO:0030424=GO_REF:0000024, GO:0048471=GO_REF:0000024, GO:0005886=GO_REF:0000039, GO:0033504=GO_REF:0000024, GO:0001757=GO_REF:0000024, GO:0005884=GO_REF:0000024, GO:0001843=GO_REF:0000024, GO:0003779=GO_REF:0000002, GO:0048565=GO_REF:0000024, GO:0044294=GO_REF:0000024, GO:0044295=GO_REF:0000024, GO:0001726=GO_REF:0000024, GO:0030425=GO_REF:0000024, GO:0001889=GO_REF:0000024, GO:0003785=GO_REF:0000024, GO:0000578=GO_REF:0000024, GO:0016020=GO_REF:0000024, GO:0051639=GO_REF:0000024, GO:0048669=GO_REF:0000024, GO:0030041=GO_REF:0000024, GO:0043025=GO_REF:0000024, GO:0030903=GO_REF:0000024, GO:0005938=GO_REF:0000024, GO:1900006=GO_REF:0000024} O75128 Protein cordon-bleu protein 20120808 {GO:0030424=ISS, GO:0048471=ISS, GO:0005886=IEA, GO:0033504=ISS, GO:0001757=ISS, GO:0005884=ISS, GO:0001843=ISS, GO:0003779=IEA, GO:0048565=ISS, GO:0044294=ISS, GO:0044295=ISS, GO:0001726=ISS, GO:0030425=ISS, GO:0001889=ISS, GO:0003785=ISS, GO:0000578=ISS, GO:0016020=ISS, GO:0051639=ISS, GO:0048669=ISS, GO:0030041=ISS, GO:0043025=ISS, GO:0030903=ISS, GO:0005938=ISS, GO:1900006=ISS} actin filament network formation, actin filament polymerization, collateral sprouting in absence of injury, digestive tract development, embryonic axis specification, floor plate development, liver development, neural tube closure, notochord development, positive regulation of dendrite development, somite specification actin filament, axon, axonal growth cone, cell cortex, dendrite, dendritic growth cone, membrane, neuronal cell body, perinuclear region of cytoplasm, plasma membrane, ruffle actin binding, actin monomer binding Human UniProtKB:Q5NBX1 COBLL1 InterPro UniProtKB {GO:0003779=GO_REF:0000002} Q53SF7 Cordon-bleu protein-like 1 protein 20130413 {GO:0003779=IEA} actin binding Human InterPro:IPR003124 COCH UniProtKB UniProtKB {GO:0005515=PMID:21886777, GO:0008360=PMID:21886777, GO:0007605=GO_REF:0000019, GO:0005578=GO_REF:0000039} O43405 Cochlin protein 20120615 {GO:0005515=IPI, GO:0008360=IMP, GO:0007605=IEA, GO:0005578=IEA} regulation of cell shape, sensory perception of sound proteinaceous extracellular matrix protein binding Human COG1 IntAct UniProtKB {GO:0005515=PMID:15047703, GO:0005794=PMID:11980916, GO:0000139=GO_REF:0000039, GO:0007030=PMID:11980916, GO:0006891=PMID:11980916, GO:0017119=PMID:15047703, GO:0015031=GO_REF:0000037} Q8WTW3 Conserved oligomeric Golgi complex subunit 1 protein 20130415 {GO:0005515=IPI, GO:0005794=IDA, GO:0000139=IEA, GO:0007030=NAS, GO:0006891=NAS, GO:0017119=IDA, GO:0015031=IEA} Golgi organization, intra-Golgi vesicle-mediated transport, protein transport Golgi apparatus, Golgi membrane, Golgi transport complex protein binding Human UniProtKB:Q9H9E3 COG2 IntAct UniProtKB {GO:0005515=PMID:15047703, GO:0009312=PMID:7962052, GO:0005795=PMID:7962052, GO:0000139=GO_REF:0000039, GO:0016020=GO_REF:0000002, GO:0008565=PMID:7962052, GO:0007030=PMID:7962052, GO:0017119=PMID:15047703, GO:0006891=PMID:7962052, GO:0006486=PMID:7962052, GO:0015031=GO_REF:0000002, GO:0006886=PMID:7962052} Q14746 Conserved oligomeric Golgi complex subunit 2 protein 20130415 {GO:0005515=IPI, GO:0009312=TAS, GO:0005795=IDA, GO:0000139=IEA, GO:0016020=IEA, GO:0008565=IMP, GO:0007030=IMP, GO:0017119=IDA, GO:0006891=IMP, GO:0006486=TAS, GO:0015031=IEA, GO:0006886=TAS} Golgi organization, intra-Golgi vesicle-mediated transport, intracellular protein transport, oligosaccharide biosynthetic process, protein glycosylation, protein transport Golgi membrane, Golgi stack, Golgi transport complex, membrane protein binding, protein transporter activity Human UniProtKB:Q9H9E3 COG3 HPA UniProtKB {GO:0005515=PMID:19536132, GO:0005801=GO_REF:0000002, GO:0005794=GO_REF:0000052, GO:0005886=GO_REF:0000052, GO:0033365=PMID:16420527, GO:0006890=PMID:16420527, GO:0005730=GO_REF:0000052, GO:0050821=PMID:16420527, GO:0006891=PMID:11929878, GO:0005634=GO_REF:0000052, GO:0006886=GO_REF:0000002, GO:0006888=PMID:11929878, GO:0005737=GO_REF:0000052, GO:0032580=GO_REF:0000039, GO:0008565=PMID:11929878, GO:0017119=PMID:15047703, GO:0006486=PMID:16420527} Q96JB2 Conserved oligomeric Golgi complex subunit 3 protein 20110516 {GO:0005515=IPI, GO:0005801=IEA, GO:0005794=IDA, GO:0005886=IDA, GO:0033365=IMP, GO:0006890=IMP, GO:0005730=IDA, GO:0050821=IMP, GO:0006891=IDA, GO:0005634=IDA, GO:0006886=IEA, GO:0006888=IDA, GO:0005737=IDA, GO:0032580=IEA, GO:0008565=IDA, GO:0017119=IDA, GO:0006486=IMP} ER to Golgi vesicle-mediated transport, intra-Golgi vesicle-mediated transport, intracellular protein transport, protein glycosylation, protein localization to organelle, protein stabilization, retrograde vesicle-mediated transport, Golgi to ER Golgi apparatus, Golgi cisterna membrane, Golgi transport complex, cis-Golgi network, cytoplasm, nucleolus, nucleus, plasma membrane protein binding, protein transporter activity Human COG4 IntAct UniProtKB {GO:0005515=PMID:15047703, GO:0048213=PMID:19536132, GO:0000139=GO_REF:0000039, GO:0006890=PMID:19536132, GO:0007030=PMID:19536132, GO:0017119=PMID:15047703, GO:0015031=GO_REF:0000037} Q9H9E3 Conserved oligomeric Golgi complex subunit 4 protein 20130415 {GO:0005515=IPI, GO:0048213=IMP, GO:0000139=IEA, GO:0006890=IMP, GO:0007030=IMP, GO:0017119=IDA, GO:0015031=IEA} Golgi organization, Golgi vesicle prefusion complex stabilization, protein transport, retrograde vesicle-mediated transport, Golgi to ER Golgi membrane, Golgi transport complex protein binding Human UniProtKB:Q9UP83 COG5 HPA UniProtKB {GO:0005515=PMID:15047703, GO:0003674=GO_REF:0000015, GO:0005794=GO_REF:0000052, GO:0000139=GO_REF:0000039, GO:0005730=GO_REF:0000052, GO:0006891=PMID:9792665, GO:0017119=PMID:15047703, GO:0005634=GO_REF:0000052, GO:0015031=GO_REF:0000037, GO:0005829=GO_REF:0000039} Q9UP83 Conserved oligomeric Golgi complex subunit 5 protein 20100326 {GO:0005515=IPI, GO:0003674=ND, GO:0005794=IDA, GO:0000139=IEA, GO:0005730=IDA, GO:0006891=NAS, GO:0017119=IDA, GO:0005634=IDA, GO:0015031=IEA, GO:0005829=IEA} intra-Golgi vesicle-mediated transport, protein transport Golgi apparatus, Golgi membrane, Golgi transport complex, cytosol, nucleolus, nucleus molecular_function, protein binding Human COG6 UniProtKB UniProtKB {GO:0070085=PMID:20605848, GO:0000139=GO_REF:0000039, GO:0017119=PMID:15047703, GO:0006891=GO_REF:0000002, GO:0015031=GO_REF:0000037} Q9Y2V7 Conserved oligomeric Golgi complex subunit 6 protein 20120618 {GO:0070085=IMP, GO:0000139=IEA, GO:0017119=IDA, GO:0006891=IEA, GO:0015031=IEA} glycosylation, intra-Golgi vesicle-mediated transport, protein transport Golgi membrane, Golgi transport complex Human COG7 IntAct UniProtKB {GO:0005515=PMID:21903422, GO:0005794=PMID:11980916, GO:0033365=PMID:16420527, GO:0000139=GO_REF:0000039, GO:0034067=PMID:16510524, GO:0006890=PMID:16420527, GO:0050821=PMID:16420527, GO:0017119=PMID:15047703, GO:0006486=PMID:16420527, GO:0006886=PMID:15107842} P83436 Conserved oligomeric Golgi complex subunit 7 protein 20130415 {GO:0005515=IPI, GO:0005794=IDA, GO:0033365=IMP, GO:0000139=IEA, GO:0034067=IMP, GO:0006890=IMP, GO:0050821=IMP, GO:0017119=IDA, GO:0006486=IMP, GO:0006886=IMP} intracellular protein transport, protein glycosylation, protein localization to Golgi apparatus, protein localization to organelle, protein stabilization, retrograde vesicle-mediated transport, Golgi to ER Golgi apparatus, Golgi membrane, Golgi transport complex protein binding Human UniProtKB:P70191 COG8 UniProtKB UniProtKB {GO:0000139=GO_REF:0000039, GO:0017119=PMID:15047703, GO:0015031=GO_REF:0000037} Q96MW5 Conserved oligomeric Golgi complex subunit 8 protein 20071221 {GO:0000139=IEA, GO:0017119=IDA, GO:0015031=IEA} protein transport Golgi membrane, Golgi transport complex Human COIL BHF-UCL UniProtKB {GO:0005515=PMID:21920476, GO:0001674=GO_REF:0000019, GO:0015030=PMID:16687569, GO:0005730=PMID:12757932, GO:0015036=GO_REF:0000019, GO:0005634=PMID:7971277, GO:0005654=PMID:12757932, GO:0008022=PMID:12757932, GO:0042802=PMID:16713569} P38432 Coilin protein 20091118 {GO:0005515=IPI, GO:0001674=IEA, GO:0015030=IDA, GO:0005730=IDA, GO:0015036=IEA, GO:0005634=TAS, GO:0005654=IDA, GO:0008022=IPI, GO:0042802=IPI} Cajal body, female germ cell nucleus, nucleolus, nucleoplasm, nucleus disulfide oxidoreductase activity, identical protein binding, protein C-terminus binding, protein binding Human COL10A1 ENSEMBL UniProtKB {GO:0001501=PMID:8554571, GO:0005581=GO_REF:0000019, GO:0022617=Reactome:REACT_118572, GO:0030198=Reactome:REACT_118779, GO:0030574=Reactome:REACT_150401, GO:0005788=Reactome:REACT_121366, GO:0005576=Reactome:REACT_150398, GO:0005938=GO_REF:0000019, GO:0046872=GO_REF:0000037} Q5QPC8 Collagen alpha-1(X) chain protein 20130413 {GO:0001501=TAS, GO:0005581=IEA, GO:0022617=TAS, GO:0030198=TAS, GO:0030574=TAS, GO:0005788=TAS, GO:0005576=TAS, GO:0005938=IEA, GO:0046872=IEA} collagen catabolic process, extracellular matrix disassembly, extracellular matrix organization, skeletal system development cell cortex, collagen, endoplasmic reticulum lumen, extracellular region metal ion binding Human Ensembl:ENSMUSP00000101150 COL11A1 Reactome UniProtKB {GO:0042472=GO_REF:0000019, GO:0055010=GO_REF:0000019, GO:0005592=PMID:3182841, GO:0007605=PMID:10573014, GO:0050840=PMID:3182841, GO:0005576=Reactome:REACT_150444, GO:0048704=GO_REF:0000019, GO:0006029=GO_REF:0000019, GO:0046872=GO_REF:0000037, GO:0022617=Reactome:REACT_118572, GO:0002063=GO_REF:0000019, GO:0001502=GO_REF:0000019, GO:0030198=Reactome:REACT_118779, GO:0030199=PMID:3182841, GO:0050910=PMID:10889003, GO:0030574=Reactome:REACT_150401, GO:0005788=Reactome:REACT_121366, GO:0030674=PMID:10486316, GO:0007601=PMID:8872475, GO:0005201=PMID:10486316} P12107 Collagen alpha-1(XI) chain protein 20130301 {GO:0042472=IEA, GO:0055010=IEA, GO:0005592=IDA, GO:0007605=IMP, GO:0050840=NAS, GO:0005576=TAS, GO:0048704=IEA, GO:0006029=IEA, GO:0046872=IEA, GO:0022617=TAS, GO:0002063=IEA, GO:0001502=IEA, GO:0030198=TAS, GO:0030199=NAS, GO:0050910=IMP, GO:0030574=TAS, GO:0005788=TAS, GO:0030674=NAS, GO:0007601=IMP, GO:0005201=NAS} cartilage condensation, chondrocyte development, collagen catabolic process, collagen fibril organization, detection of mechanical stimulus involved in sensory perception of sound, embryonic skeletal system morphogenesis, extracellular matrix disassembly, extracellular matrix organization, inner ear morphogenesis, proteoglycan metabolic process, sensory perception of sound, ventricular cardiac muscle tissue morphogenesis, visual perception collagen type XI, endoplasmic reticulum lumen, extracellular region extracellular matrix binding, extracellular matrix structural constituent, metal ion binding, protein binding, bridging Human COL11A2 ENSEMBL UniProtKB {GO:0005581=GO_REF:0000038, GO:0005592=GO_REF:0000019, GO:0051216=PMID:9188673, GO:0007605=GO_REF:0000019, GO:0048705=GO_REF:0000019, GO:0005576=Reactome:REACT_150444, GO:0046872=GO_REF:0000037, GO:0001501=PMID:7859284, GO:0001894=GO_REF:0000019, GO:0001503=GO_REF:0000019, GO:0022617=Reactome:REACT_118572, GO:0030020=PMID:8838804, GO:0002062=GO_REF:0000019, GO:0030198=Reactome:REACT_118779, GO:0030199=GO_REF:0000019, GO:0030574=Reactome:REACT_150401, GO:0005840=GO_REF:0000038, GO:0005788=Reactome:REACT_121366, GO:0060021=PMID:12673280, GO:0030674=PMID:10677296, GO:0005201=GO_REF:0000002, GO:0060023=PMID:10677296} Q4VXY6 Collagen type XI alpha 2 protein 20130413 {GO:0005581=IEA, GO:0005592=IEA, GO:0051216=IMP, GO:0007605=IEA, GO:0048705=IEA, GO:0005576=TAS, GO:0046872=IEA, GO:0001501=NAS, GO:0001894=IEA, GO:0001503=IEA, GO:0022617=TAS, GO:0030020=NAS, GO:0002062=IEA, GO:0030198=TAS, GO:0030199=IEA, GO:0030574=TAS, GO:0005840=IEA, GO:0005788=TAS, GO:0060021=IMP, GO:0030674=NAS, GO:0005201=IEA, GO:0060023=IMP} cartilage development, chondrocyte differentiation, collagen catabolic process, collagen fibril organization, extracellular matrix disassembly, extracellular matrix organization, ossification, palate development, sensory perception of sound, skeletal system development, skeletal system morphogenesis, soft palate development, tissue homeostasis collagen, collagen type XI, endoplasmic reticulum lumen, extracellular region, ribosome extracellular matrix structural constituent, extracellular matrix structural constituent conferring tensile strength, metal ion binding, protein binding, bridging Human Ensembl:ENSMUSP00000084772 COL12A1 Reactome UniProtKB {GO:0001501=PMID:3476925, GO:0022617=Reactome:REACT_118572, GO:0030020=PMID:1427837, GO:0030198=Reactome:REACT_118779, GO:0030199=PMID:1427837, GO:0030574=Reactome:REACT_150401, GO:0005788=Reactome:REACT_121366, GO:0005595=PMID:1427837, GO:0005576=Reactome:REACT_150466, GO:0007155=GO_REF:0000037} Q99715 Collagen alpha-1(XII) chain protein 20130301 {GO:0001501=TAS, GO:0022617=TAS, GO:0030020=NAS, GO:0030198=TAS, GO:0030199=NAS, GO:0030574=TAS, GO:0005788=TAS, GO:0005595=NAS, GO:0005576=TAS, GO:0007155=IEA} cell adhesion, collagen catabolic process, collagen fibril organization, extracellular matrix disassembly, extracellular matrix organization, skeletal system development collagen type XII, endoplasmic reticulum lumen, extracellular region extracellular matrix structural constituent conferring tensile strength Human COL13A1 Reactome UniProtKB {GO:0005515=PMID:11956183, GO:0005886=GO_REF:0000039, GO:0005576=Reactome:REACT_150341, GO:0005600=PMID:2459707, GO:0030154=GO_REF:0000037, GO:0001958=GO_REF:0000024, GO:0016337=PMID:10865988, GO:0022617=Reactome:REACT_118572, GO:0007160=PMID:11956183, GO:0030198=Reactome:REACT_118779, GO:0005911=GO_REF:0000019, GO:0030574=Reactome:REACT_150401, GO:0005788=Reactome:REACT_121254, GO:0016021=GO_REF:0000037, GO:0008201=PMID:11956183, GO:0005201=GO_REF:0000029, GO:0001763=GO_REF:0000024} Q5TAT6 Collagen alpha-1(XIII) chain protein 20130301 {GO:0005515=IPI, GO:0005886=IEA, GO:0005576=TAS, GO:0005600=TAS, GO:0030154=IEA, GO:0001958=ISS, GO:0016337=IEP, GO:0022617=TAS, GO:0007160=IPI, GO:0030198=TAS, GO:0005911=IEA, GO:0030574=TAS, GO:0005788=TAS, GO:0016021=IEA, GO:0008201=IDA, GO:0005201=NAS, GO:0001763=ISS} cell differentiation, cell-cell adhesion, cell-matrix adhesion, collagen catabolic process, endochondral ossification, extracellular matrix disassembly, extracellular matrix organization, morphogenesis of a branching structure cell-cell junction, collagen type XIII, endoplasmic reticulum lumen, extracellular region, integral to membrane, plasma membrane extracellular matrix structural constituent, heparin binding, protein binding Human COL14A1 BHF-UCL UniProtKB {GO:0005581=PMID:9427527, GO:0005518=PMID:2187872, GO:0005578=PMID:2187872, GO:0005596=PMID:9427527, GO:0005576=Reactome:REACT_121366, GO:0031012=PMID:22261194, GO:0016337=PMID:9427527, GO:0022617=Reactome:REACT_118572, GO:0030198=Reactome:REACT_118779, GO:0030199=PMID:2187872, GO:0030574=Reactome:REACT_150401, GO:0005788=Reactome:REACT_121366, GO:0030674=PMID:9427527, GO:0005201=PMID:9427527} Q05707 Collagen alpha-1(XIV) chain protein 20120228 {GO:0005581=NAS, GO:0005518=NAS, GO:0005578=NAS, GO:0005596=NAS, GO:0005576=TAS, GO:0031012=ISS, GO:0016337=NAS, GO:0022617=TAS, GO:0030198=TAS, GO:0030199=NAS, GO:0030574=TAS, GO:0005788=TAS, GO:0030674=NAS, GO:0005201=NAS} cell-cell adhesion, collagen catabolic process, collagen fibril organization, extracellular matrix disassembly, extracellular matrix organization collagen, collagen type XIV, endoplasmic reticulum lumen, extracellular matrix, extracellular region, proteinaceous extracellular matrix collagen binding, extracellular matrix structural constituent, protein binding, bridging colocalizes_with Human UniProtKB:F1S285 COL15A1 BHF-UCL UniProtKB {GO:0005576=Reactome:REACT_150289, GO:0001525=GO_REF:0000037, GO:0005582=PMID:9651385, GO:0030154=GO_REF:0000037, GO:0005604=GO_REF:0000019, GO:0031012=PMID:22261194, GO:0007165=PMID:10891348, GO:0022617=Reactome:REACT_118572, GO:0030198=Reactome:REACT_118779, GO:0030574=Reactome:REACT_150401, GO:0005788=Reactome:REACT_121366, GO:0016021=PMID:10891348, GO:0007155=PMID:9651385, GO:0005201=PMID:9651385} P39059 Collagen alpha-1(XV) chain protein 20120228 {GO:0005576=TAS, GO:0001525=IEA, GO:0005582=TAS, GO:0030154=IEA, GO:0005604=IEA, GO:0031012=ISS, GO:0007165=NAS, GO:0022617=TAS, GO:0030198=TAS, GO:0030574=TAS, GO:0005788=TAS, GO:0016021=NAS, GO:0007155=IC, GO:0005201=IC} angiogenesis, cell adhesion, cell differentiation, collagen catabolic process, extracellular matrix disassembly, extracellular matrix organization, signal transduction basement membrane, collagen type XV, endoplasmic reticulum lumen, extracellular matrix, extracellular region, integral to membrane extracellular matrix structural constituent colocalizes_with Human UniProtKB:F1SSE8 COL16A1 Reactome UniProtKB {GO:0005515=PMID:15165854, GO:0007565=PMID:1284248, GO:0005178=PMID:16754661, GO:0022617=Reactome:REACT_118572, GO:0071230=GO_REF:0000019, GO:0030198=Reactome:REACT_118779, GO:0007229=PMID:16754661, GO:0030574=Reactome:REACT_150401, GO:0005788=Reactome:REACT_121366, GO:0005576=Reactome:REACT_121366, GO:0007155=PMID:16754661, GO:0005597=PMID:1284248} Q07092 Collagen alpha-1(XVI) chain protein 20130301 {GO:0005515=IPI, GO:0007565=TAS, GO:0005178=IDA, GO:0022617=TAS, GO:0071230=IEA, GO:0030198=TAS, GO:0007229=TAS, GO:0030574=TAS, GO:0005788=TAS, GO:0005576=TAS, GO:0007155=IDA, GO:0005597=TAS} cell adhesion, cellular response to amino acid stimulus, collagen catabolic process, extracellular matrix disassembly, extracellular matrix organization, female pregnancy, integrin-mediated signaling pathway collagen type XVI, endoplasmic reticulum lumen, extracellular region integrin binding, protein binding Human COL17A1 Reactome UniProtKB {GO:0005515=PMID:12482924, GO:0030056=PMID:12482924, GO:0005581=GO_REF:0000037, GO:0005886=Reactome:REACT_150217, GO:0034329=Reactome:REACT_20676, GO:0005576=Reactome:REACT_150205, GO:0005604=GO_REF:0000039, GO:0007160=PMID:9012408, GO:0008544=PMID:9012408, GO:0022617=Reactome:REACT_118572, GO:0030198=Reactome:REACT_118779, GO:0005911=PMID:9012408, GO:0005887=PMID:9012408, GO:0030574=Reactome:REACT_150401, GO:0031581=Reactome:REACT_20537, GO:0005788=Reactome:REACT_121254} Q9UMD9 Collagen alpha-1(XVII) chain protein 20130213 {GO:0005515=IPI, GO:0030056=IDA, GO:0005581=IEA, GO:0005886=TAS, GO:0034329=TAS, GO:0005576=TAS, GO:0005604=IEA, GO:0007160=TAS, GO:0008544=TAS, GO:0022617=TAS, GO:0030198=TAS, GO:0005911=TAS, GO:0005887=TAS, GO:0030574=TAS, GO:0031581=TAS, GO:0005788=TAS} cell junction assembly, cell-matrix adhesion, collagen catabolic process, epidermis development, extracellular matrix disassembly, extracellular matrix organization, hemidesmosome assembly basement membrane, cell-cell junction, collagen, endoplasmic reticulum lumen, extracellular region, hemidesmosome, integral to plasma membrane, plasma membrane protein binding Human COL18A1 IntAct UniProtKB {GO:0005581=GO_REF:0000037, GO:0008284=GO_REF:0000019, GO:0008285=PMID:9008168, GO:0030335=GO_REF:0000019, GO:0043065=GO_REF:0000019, GO:0005576=Reactome:REACT_150437, GO:0001525=GO_REF:0000019, GO:0046872=GO_REF:0000037, GO:0042802=PMID:16269408, GO:0005604=GO_REF:0000019, GO:0031012=GO_REF:0000002, GO:0022617=Reactome:REACT_118572, GO:0001886=GO_REF:0000019, GO:0030198=Reactome:REACT_118779, GO:0005198=GO_REF:0000002, GO:0030574=Reactome:REACT_150401, GO:0005788=Reactome:REACT_121366, GO:0009887=PMID:10942434, GO:0007155=GO_REF:0000037, GO:0007601=PMID:10942434} P39060 Collagen alpha-1(XVIII) chain protein 20130415 {GO:0005581=IEA, GO:0008284=IEA, GO:0008285=TAS, GO:0030335=IEA, GO:0043065=IEA, GO:0005576=TAS, GO:0001525=IEA, GO:0046872=IEA, GO:0042802=IPI, GO:0005604=IEA, GO:0031012=IEA, GO:0022617=TAS, GO:0001886=IEA, GO:0030198=TAS, GO:0005198=IEA, GO:0030574=TAS, GO:0005788=TAS, GO:0009887=TAS, GO:0007155=IEA, GO:0007601=TAS} angiogenesis, cell adhesion, collagen catabolic process, endothelial cell morphogenesis, extracellular matrix disassembly, extracellular matrix organization, negative regulation of cell proliferation, organ morphogenesis, positive regulation of apoptotic process, positive regulation of cell migration, positive regulation of cell proliferation, visual perception basement membrane, collagen, endoplasmic reticulum lumen, extracellular matrix, extracellular region identical protein binding, metal ion binding, structural molecule activity Human UniProtKB:P39060 COL19A1 Reactome UniProtKB {GO:0005581=PMID:7775380, GO:0005578=PMID:1639419, GO:0005576=Reactome:REACT_150411, GO:0030154=GO_REF:0000037, GO:0016337=PMID:1639419, GO:0001501=PMID:9143499, GO:0022617=Reactome:REACT_118572, GO:0007519=GO_REF:0000019, GO:0030198=Reactome:REACT_118779, GO:0030574=Reactome:REACT_150401, GO:0005788=Reactome:REACT_121366, GO:0030674=PMID:1639419, GO:0007155=PMID:7775380, GO:0005201=PMID:7775380} Q14993 Collagen alpha-1(XIX) chain protein 20130301 {GO:0005581=NAS, GO:0005578=NAS, GO:0005576=TAS, GO:0030154=IEA, GO:0016337=NAS, GO:0001501=TAS, GO:0022617=TAS, GO:0007519=IEA, GO:0030198=TAS, GO:0030574=TAS, GO:0005788=TAS, GO:0030674=NAS, GO:0007155=NAS, GO:0005201=NAS} cell adhesion, cell differentiation, cell-cell adhesion, collagen catabolic process, extracellular matrix disassembly, extracellular matrix organization, skeletal muscle tissue development, skeletal system development collagen, endoplasmic reticulum lumen, extracellular region, proteinaceous extracellular matrix extracellular matrix structural constituent, protein binding, bridging Human COL1A1 BHF-UCL UniProtKB {GO:0005515=PMID:14749390, GO:0042542=GO_REF:0000019, GO:0034504=PMID:20018240, GO:0034505=PMID:17118335, GO:0071300=GO_REF:0000019, GO:0007605=PMID:17489845, GO:0090263=PMID:20018240, GO:0010718=PMID:20018240, GO:0048706=PMID:18553566, GO:0010812=GO_REF:0000019, GO:0043434=GO_REF:0000019, GO:0071560=GO_REF:0000019, GO:0050900=Reactome:REACT_12051, GO:0015031=GO_REF:0000019, GO:0051591=GO_REF:0000019, GO:0046872=GO_REF:0000037, GO:0042802=PMID:17211858, GO:0005584=PMID:14976317, GO:0070208=GO_REF:0000019, GO:0022617=Reactome:REACT_118572, GO:0071230=GO_REF:0000019, GO:0030198=Reactome:REACT_118779, GO:0060351=GO_REF:0000019, GO:0030199=PMID:17211858, GO:0030574=Reactome:REACT_150401, GO:0030335=PMID:20018240, GO:0001568=PMID:17211858, GO:0048407=PMID:8900172, GO:0007584=GO_REF:0000019, GO:0030168=Reactome:REACT_798, GO:0031960=GO_REF:0000019, GO:0005576=Reactome:REACT_150470, GO:0001649=GO_REF:0000019, GO:0031012=PMID:22261194, GO:0001958=GO_REF:0000019, GO:0001501=PMID:8097422, GO:0001957=GO_REF:0000019, GO:0060346=GO_REF:0000019, GO:0060325=GO_REF:0000019, GO:0007596=Reactome:REACT_604, GO:0005788=Reactome:REACT_121366, GO:0043589=PMID:17211858, GO:0032964=PMID:15095409, GO:0045893=PMID:20018240, GO:0071260=GO_REF:0000019, GO:0007601=PMID:17557158, GO:0005201=GO_REF:0000019} P02452 Collagen alpha-1(I) chain protein 20120228 {GO:0005515=IPI, GO:0042542=IEA, GO:0034504=IDA, GO:0034505=IMP, GO:0071300=IEA, GO:0007605=IMP, GO:0090263=IDA, GO:0010718=IDA, GO:0048706=IMP, GO:0010812=IEA, GO:0043434=IEA, GO:0071560=IEA, GO:0050900=TAS, GO:0015031=IEA, GO:0051591=IEA, GO:0046872=IEA, GO:0042802=IDA, GO:0005584=IMP, GO:0070208=IEA, GO:0022617=TAS, GO:0071230=IEA, GO:0030198=TAS, GO:0060351=IEA, GO:0030199=IMP, GO:0030574=TAS, GO:0030335=IDA, GO:0001568=IMP, GO:0048407=IDA, GO:0007584=IEA, GO:0030168=TAS, GO:0031960=IEA, GO:0005576=TAS, GO:0001649=IEA, GO:0031012=ISS, GO:0001958=IEA, GO:0001501=IMP, GO:0001957=IEA, GO:0060346=IEA, GO:0060325=IEA, GO:0007596=TAS, GO:0005788=TAS, GO:0043589=IMP, GO:0032964=IMP, GO:0045893=IDA, GO:0071260=IEA, GO:0007601=IMP, GO:0005201=IEA} blood coagulation, blood vessel development, bone trabecula formation, cartilage development involved in endochondral bone morphogenesis, cellular response to amino acid stimulus, cellular response to mechanical stimulus, cellular response to retinoic acid, cellular response to transforming growth factor beta stimulus, collagen biosynthetic process, collagen catabolic process, collagen fibril organization, embryonic skeletal system development, endochondral ossification, extracellular matrix disassembly, extracellular matrix organization, face morphogenesis, intramembranous ossification, leukocyte migration, negative regulation of cell-substrate adhesion, osteoblast differentiation, platelet activation, positive regulation of canonical Wnt receptor signaling pathway, positive regulation of cell migration, positive regulation of epithelial to mesenchymal transition, positive regulation of transcription, DNA-dependent, protein heterotrimerization, protein localization to nucleus, protein transport, response to cAMP, response to corticosteroid stimulus, response to hydrogen peroxide, response to nutrient, response to peptide hormone stimulus, sensory perception of sound, skeletal system development, skin morphogenesis, tooth mineralization, visual perception collagen type I, endoplasmic reticulum lumen, extracellular matrix, extracellular region extracellular matrix structural constituent, identical protein binding, metal ion binding, platelet-derived growth factor binding, protein binding colocalizes_with Human UniProtKB:Q1HNM7 COL1A2 Reactome UniProtKB {GO:0005515=PMID:18375391, GO:0046332=GO_REF:0000019, GO:0007266=PMID:17217948, GO:0050900=Reactome:REACT_12051, GO:0005615=PMID:18375391, GO:0046872=GO_REF:0000037, GO:0042802=PMID:17211858, GO:0005584=PMID:18375391, GO:0070208=GO_REF:0000019, GO:0071230=GO_REF:0000019, GO:0022617=Reactome:REACT_118572, GO:0030198=Reactome:REACT_118779, GO:0030199=PMID:17211858, GO:0030574=Reactome:REACT_150401, GO:0042476=PMID:1740554, GO:0007179=PMID:17217948, GO:0030674=PMID:18375391, GO:0001568=PMID:17211858, GO:0048407=PMID:8900172, GO:0030168=Reactome:REACT_798, GO:0005576=Reactome:REACT_150470, GO:0001501=PMID:18375391, GO:0007596=Reactome:REACT_604, GO:0008217=PMID:17334644, GO:0005788=Reactome:REACT_121366, GO:0043589=PMID:17211858, GO:0005201=PMID:8982144} P08123 Collagen alpha-2(I) chain protein 20130301 {GO:0005515=IPI, GO:0046332=IEA, GO:0007266=IDA, GO:0050900=TAS, GO:0005615=IDA, GO:0046872=IEA, GO:0042802=IDA, GO:0005584=IDA, GO:0070208=IEA, GO:0071230=IEA, GO:0022617=TAS, GO:0030198=TAS, GO:0030199=IMP, GO:0030574=TAS, GO:0042476=NAS, GO:0007179=IDA, GO:0030674=IMP, GO:0001568=IMP, GO:0048407=IDA, GO:0030168=TAS, GO:0005576=TAS, GO:0001501=IMP, GO:0007596=TAS, GO:0008217=IMP, GO:0005788=TAS, GO:0043589=IMP, GO:0005201=NAS} Rho protein signal transduction, blood coagulation, blood vessel development, cellular response to amino acid stimulus, collagen catabolic process, collagen fibril organization, extracellular matrix disassembly, extracellular matrix organization, leukocyte migration, odontogenesis, platelet activation, protein heterotrimerization, regulation of blood pressure, skeletal system development, skin morphogenesis, transforming growth factor beta receptor signaling pathway collagen type I, endoplasmic reticulum lumen, extracellular region, extracellular space SMAD binding, extracellular matrix structural constituent, identical protein binding, metal ion binding, platelet-derived growth factor binding, protein binding, protein binding, bridging Human COL20A1 Reactome UniProtKB {GO:0005581=GO_REF:0000037, GO:0030198=Reactome:REACT_118779, GO:0005788=Reactome:REACT_121366, GO:0005576=Reactome:REACT_121366, GO:0005615=GO_REF:0000039} Q9P218 Collagen alpha-1(XX) chain protein 20130301 {GO:0005581=IEA, GO:0030198=TAS, GO:0005788=TAS, GO:0005576=TAS, GO:0005615=IEA} extracellular matrix organization collagen, endoplasmic reticulum lumen, extracellular region, extracellular space Human COL23A1 Reactome UniProtKB {GO:0005581=GO_REF:0000037, GO:0022617=Reactome:REACT_118572, GO:0005886=Reactome:REACT_120755, GO:0030198=Reactome:REACT_118779, GO:0030574=Reactome:REACT_150401, GO:0005788=Reactome:REACT_121366, GO:0016021=GO_REF:0000037} Q86Y22 Collagen alpha-1(XXIII) chain protein 20130301 {GO:0005581=IEA, GO:0022617=TAS, GO:0005886=TAS, GO:0030198=TAS, GO:0030574=TAS, GO:0005788=TAS, GO:0016021=IEA} collagen catabolic process, extracellular matrix disassembly, extracellular matrix organization collagen, endoplasmic reticulum lumen, integral to membrane, plasma membrane Human COL25A1 Reactome UniProtKB {GO:0005581=GO_REF:0000037, GO:0001540=PMID:11927537, GO:0022617=Reactome:REACT_118572, GO:0005886=Reactome:REACT_150355, GO:0030198=Reactome:REACT_118779, GO:0005887=PMID:11927537, GO:0030574=Reactome:REACT_150401, GO:0005788=Reactome:REACT_121254, GO:0005576=Reactome:REACT_150355, GO:0016021=PMID:11927537, GO:0008201=PMID:15522881, GO:0005615=PMID:11927537} Q9BXS0 Collagen alpha-1(XXV) chain protein 20130301 {GO:0005581=IEA, GO:0001540=IDA, GO:0022617=TAS, GO:0005886=TAS, GO:0030198=TAS, GO:0005887=IDA, GO:0030574=TAS, GO:0005788=TAS, GO:0005576=TAS, GO:0016021=NAS, GO:0008201=IDA, GO:0005615=IDA} collagen catabolic process, extracellular matrix disassembly, extracellular matrix organization collagen, endoplasmic reticulum lumen, extracellular region, extracellular space, integral to membrane, integral to plasma membrane, plasma membrane beta-amyloid binding, heparin binding Human COL27A1 Reactome UniProtKB {GO:0030198=Reactome:REACT_118779, GO:0005788=Reactome:REACT_121366, GO:0005576=Reactome:REACT_150338, GO:0005583=GO_REF:0000019, GO:0046872=GO_REF:0000037, GO:0005201=GO_REF:0000002} Q8IZC6 Collagen alpha-1(XXVII) chain protein 20130301 {GO:0030198=TAS, GO:0005788=TAS, GO:0005576=TAS, GO:0005583=IEA, GO:0046872=IEA, GO:0005201=IEA} extracellular matrix organization endoplasmic reticulum lumen, extracellular region, fibrillar collagen extracellular matrix structural constituent, metal ion binding Human COL2A1 BHF-UCL UniProtKB {GO:0010468=GO_REF:0000019, GO:0071773=GO_REF:0000019, GO:0051216=PMID:7550321, GO:0007605=PMID:16752401, GO:0005615=GO_REF:0000019, GO:0005585=PMID:8660302, GO:0046872=GO_REF:0000037, GO:0042802=PMID:2587267, GO:0030020=PMID:8660302, GO:0001894=GO_REF:0000019, GO:0022617=Reactome:REACT_118572, GO:0030198=Reactome:REACT_118779, GO:0002062=GO_REF:0000019, GO:0007411=Reactome:REACT_18266, GO:0030199=PMID:1429602, GO:0060351=GO_REF:0000019, GO:0030574=Reactome:REACT_150401, GO:0060021=GO_REF:0000019, GO:0043066=GO_REF:0000019, GO:0042472=GO_REF:0000019, GO:0071599=GO_REF:0000019, GO:0048407=PMID:8900172, GO:0005576=Reactome:REACT_150444, GO:0006029=GO_REF:0000019, GO:0007417=GO_REF:0000019, GO:0005604=GO_REF:0000019, GO:0003007=GO_REF:0000019, GO:0001958=GO_REF:0000019, GO:0001501=PMID:1429602, GO:0001502=GO_REF:0000019, GO:0060272=PMID:16752401, GO:0060174=GO_REF:0000019, GO:0005788=Reactome:REACT_121366, GO:0030903=GO_REF:0000019, GO:0007601=PMID:16752401} P02458 Collagen alpha-1(II) chain protein 20080919 {GO:0010468=IEA, GO:0071773=IEA, GO:0051216=TAS, GO:0007605=IMP, GO:0005615=IEA, GO:0005585=IDA, GO:0046872=IEA, GO:0042802=NAS, GO:0030020=IC, GO:0001894=IEA, GO:0022617=TAS, GO:0030198=TAS, GO:0002062=IEA, GO:0007411=TAS, GO:0030199=IMP, GO:0060351=IEA, GO:0030574=TAS, GO:0060021=IEA, GO:0043066=IEA, GO:0042472=IEA, GO:0071599=IEA, GO:0048407=IDA, GO:0005576=TAS, GO:0006029=IEA, GO:0007417=IEA, GO:0005604=IEA, GO:0003007=IEA, GO:0001958=IEA, GO:0001501=IMP, GO:0001502=IEA, GO:0060272=IMP, GO:0060174=IEA, GO:0005788=TAS, GO:0030903=IEA, GO:0007601=IMP} axon guidance, cartilage condensation, cartilage development, cartilage development involved in endochondral bone morphogenesis, cellular response to BMP stimulus, central nervous system development, chondrocyte differentiation, collagen catabolic process, collagen fibril organization, embryonic skeletal joint morphogenesis, endochondral ossification, extracellular matrix disassembly, extracellular matrix organization, heart morphogenesis, inner ear morphogenesis, limb bud formation, negative regulation of apoptotic process, notochord development, otic vesicle development, palate development, proteoglycan metabolic process, regulation of gene expression, sensory perception of sound, skeletal system development, tissue homeostasis, visual perception basement membrane, collagen type II, endoplasmic reticulum lumen, extracellular region, extracellular space extracellular matrix structural constituent conferring tensile strength, identical protein binding, metal ion binding, platelet-derived growth factor binding Human GO:0005594 COL3A1 Reactome UniProtKB {GO:0005515=PMID:2839553, GO:0005581=GO_REF:0000002, GO:0005586=PMID:7487954, GO:0046332=GO_REF:0000019, GO:0005615=PMID:7487954, GO:0046872=GO_REF:0000037, GO:0007507=PMID:7546986, GO:0022617=Reactome:REACT_118572, GO:0071230=GO_REF:0000019, GO:0030198=Reactome:REACT_118779, GO:0007411=Reactome:REACT_18266, GO:0030199=PMID:1672129, GO:0030574=Reactome:REACT_150401, GO:0007179=PMID:16360482, GO:0043206=PMID:14970208, GO:0034097=PMID:9076960, GO:0009314=PMID:14736764, GO:0001568=GO_REF:0000019, GO:0048407=PMID:8900172, GO:0030168=PMID:9573018, GO:0005576=Reactome:REACT_150439, GO:0048565=GO_REF:0000019, GO:0031012=PMID:7487954, GO:0001501=GO_REF:0000019, GO:0005178=PMID:9573018, GO:0018149=PMID:16754721, GO:0007160=PMID:16912226, GO:0050777=PMID:16754721, GO:0007229=PMID:14970208, GO:0042060=PMID:1466622, GO:0005788=Reactome:REACT_121366, GO:0043588=PMID:9036918, GO:0032964=PMID:2981879, GO:0005201=PMID:7487954} P02461 Collagen alpha-1(III) chain protein 20130301 {GO:0005515=IPI, GO:0005581=IEA, GO:0005586=IMP, GO:0046332=IEA, GO:0005615=IDA, GO:0046872=IEA, GO:0007507=IMP, GO:0022617=TAS, GO:0071230=IEA, GO:0030198=TAS, GO:0007411=TAS, GO:0030199=NAS, GO:0030574=TAS, GO:0007179=IDA, GO:0043206=IMP, GO:0034097=IDA, GO:0009314=IDA, GO:0001568=IEA, GO:0048407=IDA, GO:0030168=NAS, GO:0005576=TAS, GO:0048565=IEA, GO:0031012=IMP, GO:0001501=IEA, GO:0005178=IMP, GO:0018149=IDA, GO:0007160=IDA, GO:0050777=IMP, GO:0007229=IMP, GO:0042060=IDA, GO:0005788=TAS, GO:0043588=IMP, GO:0032964=IMP, GO:0005201=IMP} axon guidance, blood vessel development, cell-matrix adhesion, cellular response to amino acid stimulus, collagen biosynthetic process, collagen catabolic process, collagen fibril organization, digestive tract development, extracellular fibril organization, extracellular matrix disassembly, extracellular matrix organization, heart development, integrin-mediated signaling pathway, negative regulation of immune response, peptide cross-linking, platelet activation, response to cytokine stimulus, response to radiation, skeletal system development, skin development, transforming growth factor beta receptor signaling pathway, wound healing collagen, collagen type III, endoplasmic reticulum lumen, extracellular matrix, extracellular region, extracellular space SMAD binding, extracellular matrix structural constituent, integrin binding, metal ion binding, platelet-derived growth factor binding, protein binding Human COL4A1 BHF-UCL UniProtKB {GO:0005515=PMID:12011424, GO:0048407=PMID:8900172, GO:0005587=GO_REF:0000019, GO:0005576=Reactome:REACT_150470, GO:0001525=GO_REF:0000037, GO:0031012=PMID:22261194, GO:0071230=GO_REF:0000019, GO:0022617=Reactome:REACT_118572, GO:0007528=GO_REF:0000019, GO:0007411=Reactome:REACT_18266, GO:0030198=Reactome:REACT_118779, GO:0030574=Reactome:REACT_150401, GO:0005788=Reactome:REACT_121366, GO:0005201=GO_REF:0000002} P02462 Collagen alpha-1(IV) chain protein 20120228 {GO:0005515=IPI, GO:0048407=IDA, GO:0005587=IEA, GO:0005576=TAS, GO:0001525=IEA, GO:0031012=ISS, GO:0071230=IEA, GO:0022617=TAS, GO:0007528=IEA, GO:0007411=TAS, GO:0030198=TAS, GO:0030574=TAS, GO:0005788=TAS, GO:0005201=IEA} angiogenesis, axon guidance, cellular response to amino acid stimulus, collagen catabolic process, extracellular matrix disassembly, extracellular matrix organization, neuromuscular junction development collagen type IV, endoplasmic reticulum lumen, extracellular matrix, extracellular region extracellular matrix structural constituent, platelet-derived growth factor binding, protein binding colocalizes_with Human UniProtKB:F1KQQ4 COL4A2 BHF-UCL UniProtKB {GO:0005515=PMID:12011424, GO:0005587=PMID:2846280, GO:0071560=GO_REF:0000019, GO:0005576=Reactome:REACT_150470, GO:0001525=GO_REF:0000037, GO:0006351=GO_REF:0000019, GO:0031012=PMID:22261194, GO:0022617=Reactome:REACT_118572, GO:0030198=Reactome:REACT_118779, GO:0007411=Reactome:REACT_18266, GO:0016525=PMID:10625665, GO:0030574=Reactome:REACT_150401, GO:0005788=Reactome:REACT_121366, GO:0005201=PMID:8317999} P08572 Collagen alpha-2(IV) chain protein 20120228 {GO:0005515=IPI, GO:0005587=TAS, GO:0071560=IEA, GO:0005576=TAS, GO:0001525=IEA, GO:0006351=IEA, GO:0031012=ISS, GO:0022617=TAS, GO:0030198=TAS, GO:0007411=TAS, GO:0016525=IDA, GO:0030574=TAS, GO:0005788=TAS, GO:0005201=TAS} angiogenesis, axon guidance, cellular response to transforming growth factor beta stimulus, collagen catabolic process, extracellular matrix disassembly, extracellular matrix organization, negative regulation of angiogenesis, transcription, DNA-dependent collagen type IV, endoplasmic reticulum lumen, extracellular matrix, extracellular region extracellular matrix structural constituent, protein binding colocalizes_with Human UniProtKB:F1RLL9 COL4A3 Reactome UniProtKB {GO:0005515=PMID:12682293, GO:0008285=PMID:10837460, GO:0006919=PMID:10766752, GO:0008283=PMID:10766752, GO:0008015=PMID:10766752, GO:0007605=PMID:7987396, GO:0005587=PMID:10766752, GO:0005576=Reactome:REACT_150470, GO:0006917=PMID:10766752, GO:0032836=GO_REF:0000024, GO:0005604=PMID:10766752, GO:0005178=PMID:10766752, GO:0022617=Reactome:REACT_118572, GO:0030198=Reactome:REACT_118779, GO:0007411=Reactome:REACT_18266, GO:0005198=PMID:3025878, GO:0008191=PMID:10766752, GO:0030574=Reactome:REACT_150401, GO:0016525=PMID:10766752, GO:0005788=Reactome:REACT_121366, GO:0007155=GO_REF:0000037, GO:0007166=PMID:10766752, GO:0005201=GO_REF:0000002} Q01955 Collagen alpha-3(IV) chain protein 20130301 {GO:0005515=IPI, GO:0008285=TAS, GO:0006919=IDA, GO:0008283=IDA, GO:0008015=TAS, GO:0007605=TAS, GO:0005587=IDA, GO:0005576=TAS, GO:0006917=IDA, GO:0032836=ISS, GO:0005604=IDA, GO:0005178=TAS, GO:0022617=TAS, GO:0030198=TAS, GO:0007411=TAS, GO:0005198=NAS, GO:0008191=NAS, GO:0030574=TAS, GO:0016525=IDA, GO:0005788=TAS, GO:0007155=IEA, GO:0007166=NAS, GO:0005201=IEA} activation of cysteine-type endopeptidase activity involved in apoptotic process, axon guidance, blood circulation, cell adhesion, cell proliferation, cell surface receptor signaling pathway, collagen catabolic process, extracellular matrix disassembly, extracellular matrix organization, glomerular basement membrane development, induction of apoptosis, negative regulation of angiogenesis, negative regulation of cell proliferation, sensory perception of sound basement membrane, collagen type IV, endoplasmic reticulum lumen, extracellular region extracellular matrix structural constituent, integrin binding, metalloendopeptidase inhibitor activity, protein binding, structural molecule activity Human COL4A3BP HPA UniProtKB {GO:0005515=PMID:10212244, GO:0034976=GO_REF:0000019, GO:0048471=PMID:16895911, GO:0008283=GO_REF:0000019, GO:0006672=GO_REF:0000019, GO:0070273=PMID:14685229, GO:0005634=GO_REF:0000052, GO:0044281=Reactome:REACT_111217, GO:0005829=Reactome:REACT_19306, GO:0005739=GO_REF:0000019, GO:0006955=PMID:11007769, GO:0006936=GO_REF:0000019, GO:0006665=Reactome:REACT_19323, GO:0035621=PMID:18184806, GO:0035620=PMID:18184806, GO:0005794=GO_REF:0000052, GO:0030148=Reactome:REACT_115810, GO:0005730=GO_REF:0000052, GO:0055088=GO_REF:0000019, GO:0001701=GO_REF:0000019, GO:0007165=GO_REF:0000019, GO:0000902=GO_REF:0000019, GO:0003007=GO_REF:0000019, GO:0004672=PMID:10212244, GO:0070584=GO_REF:0000019, GO:0097001=PMID:18184806, GO:0005789=Reactome:REACT_19306, GO:0006468=PMID:10212244, GO:0007029=GO_REF:0000019} Q9Y5P4 Collagen type IV alpha-3-binding protein protein 20110516 {GO:0005515=IPI, GO:0034976=IEA, GO:0048471=IDA, GO:0008283=IEA, GO:0006672=IEA, GO:0070273=IDA, GO:0005634=IDA, GO:0044281=TAS, GO:0005829=TAS, GO:0005739=IEA, GO:0006955=NAS, GO:0006936=IEA, GO:0006665=TAS, GO:0035621=IMP, GO:0035620=IDA, GO:0005794=IDA, GO:0030148=TAS, GO:0005730=IDA, GO:0055088=IEA, GO:0001701=IEA, GO:0007165=IEA, GO:0000902=IEA, GO:0003007=IEA, GO:0004672=TAS, GO:0070584=IEA, GO:0097001=IDA, GO:0005789=TAS, GO:0006468=TAS, GO:0007029=IEA} ER to Golgi ceramide transport, cell morphogenesis, cell proliferation, ceramide metabolic process, endoplasmic reticulum organization, heart morphogenesis, immune response, in utero embryonic development, lipid homeostasis, mitochondrion morphogenesis, muscle contraction, protein phosphorylation, response to endoplasmic reticulum stress, signal transduction, small molecule metabolic process, sphingolipid biosynthetic process, sphingolipid metabolic process Golgi apparatus, cytosol, endoplasmic reticulum membrane, mitochondrion, nucleolus, nucleus, perinuclear region of cytoplasm ceramide binding, ceramide transporter activity, phosphatidylinositol-4-phosphate binding, protein binding, protein kinase activity Human COL4A4 Reactome UniProtKB {GO:0005581=GO_REF:0000038, GO:0022617=Reactome:REACT_118572, GO:0030198=Reactome:REACT_118779, GO:0007411=Reactome:REACT_18266, GO:0030574=Reactome:REACT_150401, GO:0005605=PMID:2211832, GO:0005587=PMID:7523402, GO:0005788=Reactome:REACT_121366, GO:0005576=Reactome:REACT_150470, GO:0032836=PMID:17942953, GO:0005201=PMID:17942953} P53420 Collagen alpha-4(IV) chain protein 20130301 {GO:0005581=IEA, GO:0022617=TAS, GO:0030198=TAS, GO:0007411=TAS, GO:0030574=TAS, GO:0005605=IDA, GO:0005587=IDA, GO:0005788=TAS, GO:0005576=TAS, GO:0032836=IMP, GO:0005201=IMP} axon guidance, collagen catabolic process, extracellular matrix disassembly, extracellular matrix organization, glomerular basement membrane development basal lamina, collagen, collagen type IV, endoplasmic reticulum lumen, extracellular region extracellular matrix structural constituent Human COL4A5 Reactome UniProtKB {GO:0005581=GO_REF:0000038, GO:0031594=GO_REF:0000019, GO:0022617=Reactome:REACT_118572, GO:0030198=Reactome:REACT_118779, GO:0007411=Reactome:REACT_18266, GO:0007528=GO_REF:0000019, GO:0030574=Reactome:REACT_150401, GO:0005605=GO_REF:0000019, GO:0005587=GO_REF:0000019, GO:0005788=Reactome:REACT_121366, GO:0005576=Reactome:REACT_150470, GO:0005201=GO_REF:0000002} P29400 Collagen alpha-5(IV) chain protein 20130301 {GO:0005581=IEA, GO:0031594=IEA, GO:0022617=TAS, GO:0030198=TAS, GO:0007411=TAS, GO:0007528=IEA, GO:0030574=TAS, GO:0005605=IEA, GO:0005587=IEA, GO:0005788=TAS, GO:0005576=TAS, GO:0005201=IEA} axon guidance, collagen catabolic process, extracellular matrix disassembly, extracellular matrix organization, neuromuscular junction development basal lamina, collagen, collagen type IV, endoplasmic reticulum lumen, extracellular region, neuromuscular junction extracellular matrix structural constituent Human COL4A6 Reactome UniProtKB {GO:0005581=GO_REF:0000038, GO:0022617=Reactome:REACT_118572, GO:0071230=GO_REF:0000019, GO:0030198=Reactome:REACT_118779, GO:0030574=Reactome:REACT_150401, GO:0005587=PMID:8125972, GO:0005788=Reactome:REACT_121366, GO:0005576=Reactome:REACT_150470, GO:0007155=GO_REF:0000037, GO:0005201=GO_REF:0000029} Q14031 Collagen alpha-6(IV) chain protein 20130301 {GO:0005581=IEA, GO:0022617=TAS, GO:0071230=IEA, GO:0030198=TAS, GO:0030574=TAS, GO:0005587=NAS, GO:0005788=TAS, GO:0005576=TAS, GO:0007155=IEA, GO:0005201=NAS} cell adhesion, cellular response to amino acid stimulus, collagen catabolic process, extracellular matrix disassembly, extracellular matrix organization collagen, collagen type IV, endoplasmic reticulum lumen, extracellular region extracellular matrix structural constituent Human COL5A1 Reactome UniProtKB {GO:0005581=GO_REF:0000002, GO:0035313=PMID:18305566, GO:0048592=PMID:16431952, GO:0005588=PMID:9683580, GO:0046872=GO_REF:0000037, GO:0022617=Reactome:REACT_118572, GO:0030198=Reactome:REACT_118779, GO:0007411=Reactome:REACT_18266, GO:0030199=PMID:15095409, GO:0030574=Reactome:REACT_150401, GO:0045112=PMID:18305566, GO:0043206=PMID:14970208, GO:0007155=PMID:18305566, GO:0008201=PMID:2203476, GO:0001568=GO_REF:0000019, GO:0048407=PMID:8900172, GO:0043394=PMID:9099729, GO:0005576=Reactome:REACT_150374, GO:0005604=GO_REF:0000019, GO:0031012=PMID:14970208, GO:0003007=GO_REF:0000019, GO:0005178=PMID:14970208, GO:0016477=PMID:18305566, GO:0051128=GO_REF:0000019, GO:0005788=Reactome:REACT_121366, GO:0043588=PMID:9683580, GO:0032964=PMID:15095409, GO:0005201=GO_REF:0000019} P20908 Collagen alpha-1(V) chain protein 20130301 {GO:0005581=IEA, GO:0035313=IMP, GO:0048592=IMP, GO:0005588=IMP, GO:0046872=IEA, GO:0022617=TAS, GO:0030198=TAS, GO:0007411=TAS, GO:0030199=IMP, GO:0030574=TAS, GO:0045112=IMP, GO:0043206=IMP, GO:0007155=IMP, GO:0008201=IDA, GO:0001568=IEA, GO:0048407=IDA, GO:0043394=IPI, GO:0005576=TAS, GO:0005604=IEA, GO:0031012=IMP, GO:0003007=IEA, GO:0005178=NAS, GO:0016477=IMP, GO:0051128=IEA, GO:0005788=TAS, GO:0043588=IMP, GO:0032964=IMP, GO:0005201=IEA} axon guidance, blood vessel development, cell adhesion, cell migration, collagen biosynthetic process, collagen catabolic process, collagen fibril organization, extracellular fibril organization, extracellular matrix disassembly, extracellular matrix organization, eye morphogenesis, heart morphogenesis, integrin biosynthetic process, regulation of cellular component organization, skin development, wound healing, spreading of epidermal cells basement membrane, collagen, collagen type V, endoplasmic reticulum lumen, extracellular matrix, extracellular region extracellular matrix structural constituent, heparin binding, integrin binding, metal ion binding, platelet-derived growth factor binding, proteoglycan binding Human COL5A2 Reactome UniProtKB {GO:0046332=GO_REF:0000019, GO:0048592=PMID:16431952, GO:0005576=Reactome:REACT_150374, GO:0005588=PMID:9425231, GO:0046872=GO_REF:0000037, GO:0031012=PMID:17666000, GO:0003674=GO_REF:0000015, GO:0001501=GO_REF:0000019, GO:0022617=Reactome:REACT_118572, GO:0071230=GO_REF:0000019, GO:0030198=Reactome:REACT_118779, GO:0007411=Reactome:REACT_18266, GO:0030199=PMID:9425231, GO:0030574=Reactome:REACT_150401, GO:0005788=Reactome:REACT_121366, GO:0043588=PMID:9425231, GO:0005201=GO_REF:0000002} P05997 Collagen alpha-2(V) chain protein 20130301 {GO:0046332=IEA, GO:0048592=IMP, GO:0005576=TAS, GO:0005588=IMP, GO:0046872=IEA, GO:0031012=NAS, GO:0003674=ND, GO:0001501=IEA, GO:0022617=TAS, GO:0071230=IEA, GO:0030198=TAS, GO:0007411=TAS, GO:0030199=IMP, GO:0030574=TAS, GO:0005788=TAS, GO:0043588=IMP, GO:0005201=IEA} axon guidance, cellular response to amino acid stimulus, collagen catabolic process, collagen fibril organization, extracellular matrix disassembly, extracellular matrix organization, eye morphogenesis, skeletal system development, skin development collagen type V, endoplasmic reticulum lumen, extracellular matrix, extracellular region SMAD binding, extracellular matrix structural constituent, metal ion binding, molecular_function Human COL5A3 Reactome UniProtKB {GO:0005518=PMID:10722718, GO:0043394=GO_REF:0000019, GO:0005576=Reactome:REACT_150374, GO:0005588=PMID:10722718, GO:0007160=GO_REF:0000019, GO:0022617=Reactome:REACT_118572, GO:0007411=Reactome:REACT_18266, GO:0030198=Reactome:REACT_118779, GO:0030199=PMID:10722718, GO:0030574=Reactome:REACT_150401, GO:0005788=Reactome:REACT_121366, GO:0043588=PMID:10722718, GO:0008201=GO_REF:0000019, GO:0005201=PMID:10722718} P25940 Collagen alpha-3(V) chain protein 20130301 {GO:0005518=NAS, GO:0043394=IEA, GO:0005576=TAS, GO:0005588=NAS, GO:0007160=IEA, GO:0022617=TAS, GO:0007411=TAS, GO:0030198=TAS, GO:0030199=NAS, GO:0030574=TAS, GO:0005788=TAS, GO:0043588=NAS, GO:0008201=IEA, GO:0005201=NAS} axon guidance, cell-matrix adhesion, collagen catabolic process, collagen fibril organization, extracellular matrix disassembly, extracellular matrix organization, skin development collagen type V, endoplasmic reticulum lumen, extracellular region collagen binding, extracellular matrix structural constituent, heparin binding, proteoglycan binding Human COL6A1 BHF-UCL UniProtKB {GO:0048407=PMID:8900172, GO:0005589=PMID:2551668, GO:0005576=Reactome:REACT_150311, GO:0031012=PMID:22261194, GO:0042383=GO_REF:0000019, GO:0070208=PMID:18400749, GO:0043234=PMID:18400749, GO:0071230=GO_REF:0000019, GO:0022617=Reactome:REACT_118572, GO:0007411=Reactome:REACT_18266, GO:0030198=Reactome:REACT_118779, GO:0030574=Reactome:REACT_150401, GO:0005788=Reactome:REACT_121366, GO:0007155=GO_REF:0000029} P12109 Collagen alpha-1(VI) chain protein 20120228 {GO:0048407=IDA, GO:0005589=NAS, GO:0005576=TAS, GO:0031012=ISS, GO:0042383=IEA, GO:0070208=IPI, GO:0043234=IPI, GO:0071230=IEA, GO:0022617=TAS, GO:0007411=TAS, GO:0030198=TAS, GO:0030574=TAS, GO:0005788=TAS, GO:0007155=NAS} axon guidance, cell adhesion, cellular response to amino acid stimulus, collagen catabolic process, extracellular matrix disassembly, extracellular matrix organization, protein heterotrimerization collagen type VI, endoplasmic reticulum lumen, extracellular matrix, extracellular region, protein complex, sarcolemma platelet-derived growth factor binding colocalizes_with Human UniProtKB:Q1T7A8 COL6A2 BHF-UCL UniProtKB {GO:0005515=PMID:12812986, GO:0005581=GO_REF:0000037, GO:0005578=GO_REF:0000029, GO:0005576=Reactome:REACT_150311, GO:0031012=PMID:22261194, GO:0042383=GO_REF:0000019, GO:0070208=PMID:18400749, GO:0043234=PMID:18400749, GO:0016337=GO_REF:0000029, GO:0022617=Reactome:REACT_118572, GO:0030198=Reactome:REACT_118779, GO:0007411=Reactome:REACT_18266, GO:0030574=Reactome:REACT_150401, GO:0005788=Reactome:REACT_121366, GO:0030674=GO_REF:0000029, GO:0005201=GO_REF:0000029} P12110 Collagen alpha-2(VI) chain protein 20120228 {GO:0005515=IPI, GO:0005581=IEA, GO:0005578=NAS, GO:0005576=TAS, GO:0031012=ISS, GO:0042383=IEA, GO:0070208=IPI, GO:0043234=IPI, GO:0016337=NAS, GO:0022617=TAS, GO:0030198=TAS, GO:0007411=TAS, GO:0030574=TAS, GO:0005788=TAS, GO:0030674=NAS, GO:0005201=NAS} axon guidance, cell-cell adhesion, collagen catabolic process, extracellular matrix disassembly, extracellular matrix organization, protein heterotrimerization collagen, endoplasmic reticulum lumen, extracellular matrix, extracellular region, protein complex, proteinaceous extracellular matrix, sarcolemma extracellular matrix structural constituent, protein binding, protein binding, bridging colocalizes_with Human UniProtKB:Q1T7A6 COL6A3 BHF-UCL UniProtKB {GO:0031012=PMID:22261194, GO:0042383=GO_REF:0000019, GO:0007517=PMID:8782832, GO:0022617=Reactome:REACT_118572, GO:0030198=Reactome:REACT_118779, GO:0007411=Reactome:REACT_18266, GO:0004867=GO_REF:0000037, GO:0030574=Reactome:REACT_150401, GO:0005788=Reactome:REACT_121366, GO:0005576=Reactome:REACT_150311, GO:0005589=PMID:8782832, GO:0007155=GO_REF:0000037} P12111 Collagen alpha-3(VI) chain protein 20120228 {GO:0031012=ISS, GO:0042383=IEA, GO:0007517=TAS, GO:0022617=TAS, GO:0030198=TAS, GO:0007411=TAS, GO:0004867=IEA, GO:0030574=TAS, GO:0005788=TAS, GO:0005576=TAS, GO:0005589=TAS, GO:0007155=IEA} axon guidance, cell adhesion, collagen catabolic process, extracellular matrix disassembly, extracellular matrix organization, muscle organ development collagen type VI, endoplasmic reticulum lumen, extracellular matrix, extracellular region, sarcolemma serine-type endopeptidase inhibitor activity colocalizes_with Human UniProtKB:Q1T7A5 COL6A5 BHF-UCL UniProtKB {GO:0031012=PMID:22261194, GO:0005581=GO_REF:0000037, GO:0022617=Reactome:REACT_118572, GO:0030198=Reactome:REACT_118779, GO:0030574=Reactome:REACT_150401, GO:0005576=Reactome:REACT_150235, GO:0007155=GO_REF:0000037} A8TX70 Collagen alpha-5(VI) chain protein 20120228 {GO:0031012=ISS, GO:0005581=IEA, GO:0022617=TAS, GO:0030198=TAS, GO:0030574=TAS, GO:0005576=TAS, GO:0007155=IEA} cell adhesion, collagen catabolic process, extracellular matrix disassembly, extracellular matrix organization collagen, extracellular matrix, extracellular region colocalizes_with Human UniProtKB:F1RS99 COL7A1 BHF-UCL UniProtKB {GO:0031012=PMID:22261194, GO:0005515=PMID:19269366, GO:0022617=Reactome:REACT_118572, GO:0008544=PMID:8170945, GO:0030198=Reactome:REACT_118779, GO:0004867=GO_REF:0000037, GO:0005590=PMID:9375848, GO:0030574=Reactome:REACT_150401, GO:0005788=Reactome:REACT_121366, GO:0005576=Reactome:REACT_150470, GO:0007155=GO_REF:0000037, GO:0005604=GO_REF:0000039} Q02388 Collagen alpha-1(VII) chain protein 20120228 {GO:0031012=ISS, GO:0005515=IPI, GO:0022617=TAS, GO:0008544=TAS, GO:0030198=TAS, GO:0004867=IEA, GO:0005590=TAS, GO:0030574=TAS, GO:0005788=TAS, GO:0005576=TAS, GO:0007155=IEA, GO:0005604=IEA} cell adhesion, collagen catabolic process, epidermis development, extracellular matrix disassembly, extracellular matrix organization basement membrane, collagen type VII, endoplasmic reticulum lumen, extracellular matrix, extracellular region protein binding, serine-type endopeptidase inhibitor activity colocalizes_with Human UniProtKB:F1SKM1 COL8A1 Reactome UniProtKB {GO:0022617=Reactome:REACT_118572, GO:0030198=Reactome:REACT_118779, GO:0005591=PMID:2029894, GO:0030574=Reactome:REACT_150401, GO:0010811=GO_REF:0000019, GO:0005788=Reactome:REACT_121366, GO:0005576=Reactome:REACT_150344, GO:0001525=GO_REF:0000037, GO:0048593=GO_REF:0000019, GO:0007155=GO_REF:0000037, GO:0050673=GO_REF:0000019, GO:0005604=GO_REF:0000039} P27658 Collagen alpha-1(VIII) chain protein 20130301 {GO:0022617=TAS, GO:0030198=TAS, GO:0005591=TAS, GO:0030574=TAS, GO:0010811=IEA, GO:0005788=TAS, GO:0005576=TAS, GO:0001525=IEA, GO:0048593=IEA, GO:0007155=IEA, GO:0050673=IEA, GO:0005604=IEA} angiogenesis, camera-type eye morphogenesis, cell adhesion, collagen catabolic process, epithelial cell proliferation, extracellular matrix disassembly, extracellular matrix organization, positive regulation of cell-substrate adhesion basement membrane, collagen type VIII, endoplasmic reticulum lumen, extracellular region Human COL8A2 Reactome UniProtKB {GO:0005581=GO_REF:0000037, GO:0005578=PMID:2019595, GO:0005576=Reactome:REACT_150344, GO:0048593=GO_REF:0000019, GO:0001525=GO_REF:0000037, GO:0050673=GO_REF:0000019, GO:0005604=PMID:2019595, GO:0016337=PMID:2019595, GO:0022617=Reactome:REACT_118572, GO:0030198=Reactome:REACT_118779, GO:0030574=Reactome:REACT_150401, GO:0005788=Reactome:REACT_121366, GO:0030674=PMID:2019595, GO:0005201=PMID:2019595} P25067 Collagen alpha-2(VIII) chain protein 20130301 {GO:0005581=IEA, GO:0005578=NAS, GO:0005576=TAS, GO:0048593=IEA, GO:0001525=IEA, GO:0050673=IEA, GO:0005604=NAS, GO:0016337=NAS, GO:0022617=TAS, GO:0030198=TAS, GO:0030574=TAS, GO:0005788=TAS, GO:0030674=NAS, GO:0005201=NAS} angiogenesis, camera-type eye morphogenesis, cell-cell adhesion, collagen catabolic process, epithelial cell proliferation, extracellular matrix disassembly, extracellular matrix organization basement membrane, collagen, endoplasmic reticulum lumen, extracellular region, proteinaceous extracellular matrix extracellular matrix structural constituent, protein binding, bridging Human COL9A1 BHF-UCL UniProtKB {GO:0003417=GO_REF:0000019, GO:0030020=PMID:8660302, GO:0022617=Reactome:REACT_118572, GO:0001894=GO_REF:0000019, GO:0030198=Reactome:REACT_118779, GO:0007411=Reactome:REACT_18266, GO:0030574=Reactome:REACT_150401, GO:0005788=Reactome:REACT_121366, GO:0009887=PMID:3473493, GO:0005576=Reactome:REACT_18390, GO:0005594=PMID:8660302, GO:0046872=GO_REF:0000037} P20849 Collagen alpha-1(IX) chain protein 20080919 {GO:0003417=IEA, GO:0030020=IC, GO:0022617=TAS, GO:0001894=IEA, GO:0030198=TAS, GO:0007411=TAS, GO:0030574=TAS, GO:0005788=TAS, GO:0009887=TAS, GO:0005576=TAS, GO:0005594=IDA, GO:0046872=IEA} axon guidance, collagen catabolic process, extracellular matrix disassembly, extracellular matrix organization, growth plate cartilage development, organ morphogenesis, tissue homeostasis collagen type IX, endoplasmic reticulum lumen, extracellular region extracellular matrix structural constituent conferring tensile strength, metal ion binding Human COL9A2 BHF-UCL UniProtKB {GO:0001501=PMID:10364514, GO:0030020=PMID:8660302, GO:0022617=Reactome:REACT_118572, GO:0030198=Reactome:REACT_118779, GO:0007411=Reactome:REACT_18266, GO:0030574=Reactome:REACT_150401, GO:0005788=Reactome:REACT_121366, GO:0005594=PMID:8660302, GO:0005576=Reactome:REACT_121366} Q14055 Collagen alpha-2(IX) chain protein 20080919 {GO:0001501=TAS, GO:0030020=IC, GO:0022617=TAS, GO:0030198=TAS, GO:0007411=TAS, GO:0030574=TAS, GO:0005788=TAS, GO:0005594=IDA, GO:0005576=TAS} axon guidance, collagen catabolic process, extracellular matrix disassembly, extracellular matrix organization, skeletal system development collagen type IX, endoplasmic reticulum lumen, extracellular region extracellular matrix structural constituent conferring tensile strength Human GO:0005594 COL9A3 BHF-UCL UniProtKB {GO:0008585=GO_REF:0000019, GO:0030020=PMID:8660302, GO:0022617=Reactome:REACT_118572, GO:0030198=Reactome:REACT_118779, GO:0007411=Reactome:REACT_18266, GO:0030574=Reactome:REACT_150401, GO:0005788=Reactome:REACT_121366, GO:0005594=PMID:8660302, GO:0005576=Reactome:REACT_121366, GO:0008584=GO_REF:0000019} Q14050 Collagen alpha-3(IX) chain protein 20080919 {GO:0008585=IEA, GO:0030020=IC, GO:0022617=TAS, GO:0030198=TAS, GO:0007411=TAS, GO:0030574=TAS, GO:0005788=TAS, GO:0005594=IDA, GO:0005576=TAS, GO:0008584=IEA} axon guidance, collagen catabolic process, extracellular matrix disassembly, extracellular matrix organization, female gonad development, male gonad development collagen type IX, endoplasmic reticulum lumen, extracellular region extracellular matrix structural constituent conferring tensile strength Human GO:0005594 COLEC12 GOC UniProtKB {GO:0005581=GO_REF:0000037, GO:0030169=PMID:11564734, GO:0006952=PMID:11162630, GO:0006910=PMID:11564734, GO:0046872=GO_REF:0000037, GO:0009756=PMID:11564734, GO:0002221=PMID:11564734, GO:0005534=PMID:11564734, GO:0045087=PMID:11564734, GO:0051260=PMID:11564734, GO:0016021=PMID:11162630, GO:0005044=PMID:11162630, GO:0008329=PMID:11564734} Q5KU26 Collectin-12 protein 20130413 {GO:0005581=IEA, GO:0030169=IDA, GO:0006952=TAS, GO:0006910=IDA, GO:0046872=IEA, GO:0009756=NAS, GO:0002221=IDA, GO:0005534=NAS, GO:0045087=TAS, GO:0051260=NAS, GO:0016021=TAS, GO:0005044=TAS, GO:0008329=IDA} carbohydrate mediated signaling, defense response, innate immune response, pattern recognition receptor signaling pathway, phagocytosis, recognition, protein homooligomerization collagen, integral to membrane galactose binding, low-density lipoprotein particle binding, metal ion binding, pattern recognition receptor activity, scavenger receptor activity Human COLQ IntAct UniProtKB {GO:0005515=PMID:15526038, GO:0005581=GO_REF:0000037, GO:0030054=GO_REF:0000037, GO:0008105=PMID:9689136, GO:0005605=PMID:9689136, GO:0001507=PMID:9689136, GO:0045202=GO_REF:0000039, GO:0005615=PMID:9689136} Q9Y215 Acetylcholinesterase collagenic tail peptide protein 20130415 {GO:0005515=IPI, GO:0005581=IEA, GO:0030054=IEA, GO:0008105=TAS, GO:0005605=TAS, GO:0001507=TAS, GO:0045202=IEA, GO:0005615=TAS} acetylcholine catabolic process in synaptic cleft, asymmetric protein localization basal lamina, cell junction, collagen, extracellular space, synapse protein binding Human UniProtKB:P22303 COMMD1 HPA UniProtKB {GO:0005515=PMID:15799966, GO:0030054=GO_REF:0000052, GO:0055070=PMID:14685266, GO:0005507=PMID:17309234, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0032434=PMID:17183367, GO:0032088=PMID:16573520, GO:0042803=PMID:15799966, GO:0042802=PMID:15799966, GO:0005737=GO_REF:0000052, GO:0031398=PMID:17183367, GO:0031462=PMID:17183367} Q8N668 COMM domain-containing protein 1 protein 20101115 {GO:0005515=IPI, GO:0030054=IDA, GO:0055070=IDA, GO:0005507=IDA, GO:0005730=IDA, GO:0005634=IDA, GO:0032434=IMP, GO:0032088=IDA, GO:0042803=IPI, GO:0042802=IPI, GO:0005737=IDA, GO:0031398=IDA, GO:0031462=IDA} copper ion homeostasis, negative regulation of NF-kappaB transcription factor activity, positive regulation of protein ubiquitination, regulation of proteasomal ubiquitin-dependent protein catabolic process Cul2-RING ubiquitin ligase complex, cell junction, cytoplasm, nucleolus, nucleus copper ion binding, identical protein binding, protein binding, protein homodimerization activity Human COMMD10 UniProtKB UniProtKB {GO:0005515=PMID:15799966} Q9Y6G5 COMM domain-containing protein 10 protein 20101213 {GO:0005515=IPI} protein binding Human UniProtKB:Q8N668 COMMD2 UniProtKB UniProtKB {GO:0005515=PMID:15799966} Q86X83 COMM domain-containing protein 2 protein 20101213 {GO:0005515=IPI} protein binding Human UniProtKB:Q8N668 COMMD3 IntAct UniProtKB {GO:0005515=PMID:15799966} Q9UBI1 COMM domain-containing protein 3 protein 20130415 {GO:0005515=IPI} protein binding Human UniProtKB:Q8N668 COMMD4 IntAct UniProtKB {GO:0005515=PMID:15799966, GO:0005737=GO_REF:0000054} Q9H0A8 COMM domain-containing protein 4 protein 20130415 {GO:0005515=IPI, GO:0005737=IDA} cytoplasm protein binding Human UniProtKB:Q8N668 COMMD5 UniProtKB UniProtKB {GO:0005515=PMID:15799966, GO:0005634=GO_REF:0000039} Q9GZQ3 COMM domain-containing protein 5 protein 20101213 {GO:0005515=IPI, GO:0005634=IEA} nucleus protein binding Human UniProtKB:Q8N668 COMMD6 IntAct UniProtKB {GO:0005515=PMID:15799966, GO:0005737=GO_REF:0000039, GO:0051059=PMID:16573520, GO:0032088=PMID:16573520, GO:0005634=GO_REF:0000039} Q7Z4G1 COMM domain-containing protein 6 protein 20130415 {GO:0005515=IPI, GO:0005737=IEA, GO:0051059=IPI, GO:0032088=IDA, GO:0005634=IEA} negative regulation of NF-kappaB transcription factor activity cytoplasm, nucleus NF-kappaB binding, protein binding Human UniProtKB:Q8N668 COMMD7 UniProtKB UniProtKB {GO:0005515=PMID:15799966, GO:0051059=PMID:15799966, GO:0032088=PMID:15799966, GO:0005575=GO_REF:0000015, GO:0045892=PMID:15799966, GO:0033209=PMID:15799966} Q86VX2 COMM domain-containing protein 7 protein 20101213 {GO:0005515=IPI, GO:0051059=IDA, GO:0032088=IDA, GO:0005575=ND, GO:0045892=IDA, GO:0033209=IDA} negative regulation of NF-kappaB transcription factor activity, negative regulation of transcription, DNA-dependent, tumor necrosis factor-mediated signaling pathway cellular_component NF-kappaB binding, protein binding Human UniProtKB:Q8N668 COMMD8 UniProtKB UniProtKB {GO:0005515=PMID:15799966} Q9NX08 COMM domain-containing protein 8 protein 20101213 {GO:0005515=IPI} protein binding Human UniProtKB:Q8N668 COMMD9 null null {} null null null null {} null null null COMP UniProtKB UniProtKB {GO:0005515=PMID:16051604, GO:0003417=GO_REF:0000019, GO:0043066=PMID:17993464, GO:0005509=PMID:11084047, GO:0005518=PMID:11084047, GO:0005578=GO_REF:0000039, GO:0006915=GO_REF:0000037, GO:0005576=GO_REF:0000002, GO:0043395=PMID:17588949, GO:0001501=PMID:7670472, GO:0009887=PMID:7713493, GO:0060173=PMID:16542502, GO:0007155=GO_REF:0000037, GO:0008201=PMID:17588949, GO:0005201=PMID:7713493} P49747 Cartilage oligomeric matrix protein protein 20090909 {GO:0005515=IPI, GO:0003417=IEA, GO:0043066=IDA, GO:0005509=IDA, GO:0005518=IDA, GO:0005578=IEA, GO:0006915=IEA, GO:0005576=IEA, GO:0043395=IDA, GO:0001501=TAS, GO:0009887=TAS, GO:0060173=IDA, GO:0007155=IEA, GO:0008201=IDA, GO:0005201=TAS} apoptotic process, cell adhesion, growth plate cartilage development, limb development, negative regulation of apoptotic process, organ morphogenesis, skeletal system development extracellular region, proteinaceous extracellular matrix calcium ion binding, collagen binding, extracellular matrix structural constituent, heparan sulfate proteoglycan binding, heparin binding, protein binding Human UniProtKB:P08648 COMT HPA UniProtKB {GO:0014070=GO_REF:0000019, GO:0006805=Reactome:REACT_13433, GO:0005886=Reactome:REACT_15553, GO:0007268=Reactome:REACT_13685, GO:0044281=Reactome:REACT_111217, GO:0032259=Reactome:REACT_6946, GO:0043231=GO_REF:0000052, GO:0050668=GO_REF:0000019, GO:0005829=Reactome:REACT_6885, GO:0005739=GO_REF:0000019, GO:0048609=GO_REF:0000019, GO:0045963=GO_REF:0000019, GO:0032496=GO_REF:0000019, GO:0007612=GO_REF:0000019, GO:0007565=GO_REF:0000019, GO:0000287=GO_REF:0000002, GO:0042493=GO_REF:0000019, GO:0016206=GO_REF:0000003, GO:0048662=GO_REF:0000019, GO:0008171=PMID:1707278, GO:0008210=GO_REF:0000019, GO:0016020=GO_REF:0000019, GO:0006584=GO_REF:0000002, GO:0042420=GO_REF:0000019, GO:0048265=GO_REF:0000019, GO:0042136=Reactome:REACT_13583, GO:0016021=GO_REF:0000037, GO:0042135=GO_REF:0000037} P21964 Catechol O-methyltransferase protein 20101115 {GO:0014070=IEA, GO:0006805=TAS, GO:0005886=TAS, GO:0007268=TAS, GO:0044281=TAS, GO:0032259=TAS, GO:0043231=IDA, GO:0050668=IEA, GO:0005829=TAS, GO:0005739=IEA, GO:0048609=IEA, GO:0045963=IEA, GO:0032496=IEA, GO:0007612=IEA, GO:0007565=IEA, GO:0000287=IEA, GO:0042493=IEA, GO:0016206=IEA, GO:0048662=IEA, GO:0008171=TAS, GO:0008210=IEA, GO:0016020=IEA, GO:0006584=IEA, GO:0042420=IEA, GO:0048265=IEA, GO:0042136=TAS, GO:0016021=IEA, GO:0042135=IEA} catecholamine metabolic process, dopamine catabolic process, estrogen metabolic process, female pregnancy, learning, methylation, multicellular organismal reproductive process, negative regulation of dopamine metabolic process, negative regulation of smooth muscle cell proliferation, neurotransmitter biosynthetic process, neurotransmitter catabolic process, positive regulation of homocysteine metabolic process, response to drug, response to lipopolysaccharide, response to organic cyclic compound, response to pain, small molecule metabolic process, synaptic transmission, xenobiotic metabolic process cytosol, integral to membrane, intracellular membrane-bounded organelle, membrane, mitochondrion, plasma membrane O-methyltransferase activity, catechol O-methyltransferase activity, magnesium ion binding Human COMTD1 ENSEMBL UniProtKB {GO:0005739=GO_REF:0000019, GO:0016021=GO_REF:0000037, GO:0008171=GO_REF:0000002} Q86VU5 Catechol O-methyltransferase domain-containing protein 1 protein 20130413 {GO:0005739=IEA, GO:0016021=IEA, GO:0008171=IEA} integral to membrane, mitochondrion O-methyltransferase activity Human Ensembl:ENSMUSP00000119330 COPA Reactome UniProtKB {GO:0005737=PMID:9115636, GO:0030126=PMID:14729954, GO:0005179=GO_REF:0000037, GO:0005198=GO_REF:0000002, GO:0006890=Reactome:REACT_11208, GO:0030157=PMID:1429581, GO:0005615=PMID:1429581, GO:0006886=GO_REF:0000002, GO:0048205=Reactome:REACT_11096, GO:0016044=Reactome:REACT_11123, GO:0005829=Reactome:REACT_11243} P53621 Coatomer subunit alpha protein 20130213 {GO:0005737=IDA, GO:0030126=IDA, GO:0005179=IEA, GO:0005198=IEA, GO:0006890=TAS, GO:0030157=IDA, GO:0005615=IDA, GO:0006886=IEA, GO:0048205=TAS, GO:0016044=TAS, GO:0005829=TAS} COPI coating of Golgi vesicle, cellular membrane organization, intracellular protein transport, pancreatic juice secretion, retrograde vesicle-mediated transport, Golgi to ER COPI vesicle coat, cytoplasm, cytosol, extracellular space hormone activity, structural molecule activity Human COPB1 Reactome UniProtKB {GO:0005515=PMID:18556652, GO:0030126=GO_REF:0000024, GO:0005793=GO_REF:0000039, GO:0005886=GO_REF:0000039, GO:0006890=Reactome:REACT_11208, GO:0005798=PMID:1840503, GO:0006891=GO_REF:0000024, GO:0006886=GO_REF:0000002, GO:0048205=Reactome:REACT_11096, GO:0030117=GO_REF:0000002, GO:0005829=Reactome:REACT_11243, GO:0000139=PMID:1840503, GO:0005198=GO_REF:0000002, GO:0019048=GO_REF:0000037, GO:0016192=GO_REF:0000002, GO:0016044=Reactome:REACT_11123} P53618 Coatomer subunit beta protein 20130213 {GO:0005515=IPI, GO:0030126=ISS, GO:0005793=IEA, GO:0005886=IEA, GO:0006890=TAS, GO:0005798=TAS, GO:0006891=ISS, GO:0006886=IEA, GO:0048205=TAS, GO:0030117=IEA, GO:0005829=TAS, GO:0000139=TAS, GO:0005198=IEA, GO:0019048=IEA, GO:0016192=IEA, GO:0016044=TAS} COPI coating of Golgi vesicle, cellular membrane organization, intra-Golgi vesicle-mediated transport, intracellular protein transport, retrograde vesicle-mediated transport, Golgi to ER, vesicle-mediated transport, virus-host interaction COPI vesicle coat, Golgi membrane, Golgi-associated vesicle, cytosol, endoplasmic reticulum-Golgi intermediate compartment, membrane coat, plasma membrane protein binding, structural molecule activity Human COPB2 HPA UniProtKB {GO:0030126=PMID:14729954, GO:0005794=GO_REF:0000052, GO:0006890=Reactome:REACT_11208, GO:0006891=PMID:8335000, GO:0015629=GO_REF:0000052, GO:0006886=GO_REF:0000002, GO:0030117=GO_REF:0000002, GO:0048205=Reactome:REACT_11096, GO:0005829=Reactome:REACT_11243, GO:0005737=GO_REF:0000052, GO:0005198=GO_REF:0000002, GO:0016192=GO_REF:0000002, GO:0016044=Reactome:REACT_11123} P35606 Coatomer subunit beta' protein 20110516 {GO:0030126=IDA, GO:0005794=IDA, GO:0006890=TAS, GO:0006891=IDA, GO:0015629=IDA, GO:0006886=IEA, GO:0030117=IEA, GO:0048205=TAS, GO:0005829=TAS, GO:0005737=IDA, GO:0005198=IEA, GO:0016192=IEA, GO:0016044=TAS} COPI coating of Golgi vesicle, cellular membrane organization, intra-Golgi vesicle-mediated transport, intracellular protein transport, retrograde vesicle-mediated transport, Golgi to ER, vesicle-mediated transport COPI vesicle coat, Golgi apparatus, actin cytoskeleton, cytoplasm, cytosol, membrane coat structural molecule activity Human COPE LIFEdb UniProtKB {GO:0030126=GO_REF:0000024, GO:0005794=GO_REF:0000054, GO:0005198=GO_REF:0000002, GO:0006890=Reactome:REACT_11208, GO:0006891=GO_REF:0000024, GO:0015031=GO_REF:0000037, GO:0048205=Reactome:REACT_11096, GO:0016044=Reactome:REACT_11123, GO:0005829=Reactome:REACT_11243} O14579 Coatomer subunit epsilon protein 20100607 {GO:0030126=ISS, GO:0005794=IDA, GO:0005198=IEA, GO:0006890=TAS, GO:0006891=ISS, GO:0015031=IEA, GO:0048205=TAS, GO:0016044=TAS, GO:0005829=TAS} COPI coating of Golgi vesicle, cellular membrane organization, intra-Golgi vesicle-mediated transport, protein transport, retrograde vesicle-mediated transport, Golgi to ER COPI vesicle coat, Golgi apparatus, cytosol structural molecule activity Human COPG2 MGI UniProtKB {GO:0030126=PMID:1472999, GO:0005198=GO_REF:0000002, GO:0006890=PMID:11030615, GO:0006891=PMID:11056392, GO:0016192=GO_REF:0000002, GO:0006886=GO_REF:0000002, GO:0030117=GO_REF:0000002} Q9UBF2 Coatomer subunit gamma-2 protein 20060111 {GO:0030126=IDA, GO:0005198=IEA, GO:0006890=TAS, GO:0006891=IDA, GO:0016192=IEA, GO:0006886=IEA, GO:0030117=IEA} intra-Golgi vesicle-mediated transport, intracellular protein transport, retrograde vesicle-mediated transport, Golgi to ER, vesicle-mediated transport COPI vesicle coat, membrane coat structural molecule activity Human COPS2 UniProtKB UniProtKB {GO:0005515=PMID:17438371, GO:0007165=PMID:9535219, GO:0005737=PMID:9535219, GO:0008180=PMID:18850735, GO:0006366=PMID:7776974, GO:0008283=GO_REF:0000019, GO:0030182=GO_REF:0000019, GO:0003714=GO_REF:0000019, GO:0010388=PMID:19141280, GO:0004871=PMID:9535219, GO:0000122=GO_REF:0000019} P61201 COP9 signalosome complex subunit 2 protein 20110518 {GO:0005515=IPI, GO:0007165=NAS, GO:0005737=IDA, GO:0008180=IDA, GO:0006366=TAS, GO:0008283=IEA, GO:0030182=IEA, GO:0003714=IEA, GO:0010388=IDA, GO:0004871=NAS, GO:0000122=IEA} cell proliferation, cullin deneddylation, negative regulation of transcription from RNA polymerase II promoter, neuron differentiation, signal transduction, transcription from RNA polymerase II promoter cytoplasm, signalosome protein binding, signal transducer activity, transcription corepressor activity Human COPS3 HPA UniProtKB {GO:0005515=PMID:12620389, GO:0007165=PMID:9535219, GO:0005737=GO_REF:0000052, GO:0008180=PMID:18850735, GO:0010388=PMID:19141280, GO:0005634=GO_REF:0000052, GO:0009416=PMID:9535219, GO:0001701=GO_REF:0000019} Q9UNS2 COP9 signalosome complex subunit 3 protein 20100326 {GO:0005515=IPI, GO:0007165=TAS, GO:0005737=IDA, GO:0008180=IDA, GO:0010388=IDA, GO:0005634=IDA, GO:0009416=TAS, GO:0001701=IEA} cullin deneddylation, in utero embryonic development, response to light stimulus, signal transduction cytoplasm, nucleus, signalosome protein binding Human COPS4 HPA UniProtKB {GO:0005515=PMID:20195357, GO:0005737=GO_REF:0000039, GO:0008180=PMID:18850735, GO:0010388=PMID:19141280, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052} Q9BT78 COP9 signalosome complex subunit 4 protein 20120912 {GO:0005515=IPI, GO:0005737=IEA, GO:0008180=IDA, GO:0010388=IDA, GO:0005730=IDA, GO:0005634=IDA} cullin deneddylation cytoplasm, nucleolus, nucleus, signalosome protein binding NOT Human COPS5 GOC UniProtKB {GO:0005515=PMID:21499297, GO:0000338=PMID:19214193, GO:0048471=GO_REF:0000039, GO:0005852=PMID:9341143, GO:0006366=PMID:8837781, GO:0003713=PMID:8837781, GO:0010388=PMID:19141280, GO:0005730=GO_REF:0000052, GO:0003743=PMID:9341143, GO:0005634=GO_REF:0000052, GO:0006412=PMID:9341143, GO:0006413=PMID:9341143, GO:0046872=GO_REF:0000037, GO:0046328=PMID:16410250, GO:0005737=PMID:17050680, GO:0008180=PMID:18850735, GO:0045944=PMID:16410250, GO:0051726=GO_REF:0000019, GO:0006508=GO_REF:0000037, GO:0008237=PMID:19214193} Q92905 COP9 signalosome complex subunit 5 protein 20130413 {GO:0005515=IPI, GO:0000338=IMP, GO:0048471=IEA, GO:0005852=TAS, GO:0006366=TAS, GO:0003713=TAS, GO:0010388=IDA, GO:0005730=IDA, GO:0003743=TAS, GO:0005634=IDA, GO:0006412=TAS, GO:0006413=TAS, GO:0046872=IEA, GO:0046328=IDA, GO:0005737=IDA, GO:0008180=IDA, GO:0045944=IDA, GO:0051726=IEA, GO:0006508=IEA, GO:0008237=IMP} cullin deneddylation, positive regulation of transcription from RNA polymerase II promoter, protein deneddylation, proteolysis, regulation of JNK cascade, regulation of cell cycle, transcription from RNA polymerase II promoter, translation, translational initiation cytoplasm, eukaryotic translation initiation factor 3 complex, nucleolus, nucleus, perinuclear region of cytoplasm, signalosome metal ion binding, metallopeptidase activity, protein binding, transcription coactivator activity, translation initiation factor activity Human COPS6 HPA UniProtKB {GO:0005515=PMID:21625211, GO:0005737=GO_REF:0000039, GO:0008180=PMID:18850735, GO:0019048=GO_REF:0000037, GO:0010388=PMID:19141280, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052} Q7L5N1 COP9 signalosome complex subunit 6 protein 20111111 {GO:0005515=IPI, GO:0005737=IEA, GO:0008180=IDA, GO:0019048=IEA, GO:0010388=IDA, GO:0005730=IDA, GO:0005634=IDA} cullin deneddylation, virus-host interaction cytoplasm, nucleolus, nucleus, signalosome protein binding NOT Human COPS7A HPA UniProtKB {GO:0005737=GO_REF:0000052, GO:0008180=PMID:18850735, GO:0010388=PMID:19141280, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052} Q9UBW8 COP9 signalosome complex subunit 7a protein 20101115 {GO:0005737=IDA, GO:0008180=IDA, GO:0010388=IDA, GO:0005730=IDA, GO:0005634=IDA} cullin deneddylation cytoplasm, nucleolus, nucleus, signalosome Human COPS7B HPA UniProtKB {GO:0005737=GO_REF:0000052, GO:0008180=PMID:18850735, GO:0010388=PMID:19141280} Q9H9Q2 COP9 signalosome complex subunit 7b protein 20110516 {GO:0005737=IDA, GO:0008180=IDA, GO:0010388=IDA} cullin deneddylation cytoplasm, signalosome Human COPS8 HPA UniProtKB {GO:0005737=GO_REF:0000052, GO:0008180=PMID:18850735, GO:0010388=PMID:19141280, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052} Q99627 COP9 signalosome complex subunit 8 protein 20110516 {GO:0005737=IDA, GO:0008180=IDA, GO:0010388=IDA, GO:0005730=IDA, GO:0005634=IDA} cullin deneddylation cytoplasm, nucleolus, nucleus, signalosome Human COPZ1 Reactome UniProtKB {GO:0030126=PMID:14729954, GO:0006890=Reactome:REACT_11208, GO:0006810=GO_REF:0000002, GO:0006891=GO_REF:0000024, GO:0016192=GO_REF:0000002, GO:0006886=GO_REF:0000002, GO:0048205=Reactome:REACT_11096, GO:0016044=Reactome:REACT_11123, GO:0030117=GO_REF:0000002, GO:0005829=Reactome:REACT_11243} P61923 Coatomer subunit zeta-1 protein 20130213 {GO:0030126=IDA, GO:0006890=TAS, GO:0006810=IEA, GO:0006891=ISS, GO:0016192=IEA, GO:0006886=IEA, GO:0048205=TAS, GO:0016044=TAS, GO:0030117=IEA, GO:0005829=TAS} COPI coating of Golgi vesicle, cellular membrane organization, intra-Golgi vesicle-mediated transport, intracellular protein transport, retrograde vesicle-mediated transport, Golgi to ER, transport, vesicle-mediated transport COPI vesicle coat, cytosol, membrane coat Human COPZ2 MGI UniProtKB {GO:0005801=PMID:11056392, GO:0030126=PMID:14729954, GO:0006810=GO_REF:0000002, GO:0016192=GO_REF:0000037, GO:0006886=PMID:11056392} Q9P299 Coatomer subunit zeta-2 protein 20060111 {GO:0005801=NAS, GO:0030126=IDA, GO:0006810=IEA, GO:0016192=IEA, GO:0006886=NAS} intracellular protein transport, transport, vesicle-mediated transport COPI vesicle coat, cis-Golgi network Human COQ10A UniProtKB UniProtKB {GO:0005743=GO_REF:0000039} Q96MF6 Coenzyme Q-binding protein COQ10 homolog A, mitochondrial protein 20130413 {GO:0005743=IEA} mitochondrial inner membrane Human UniProtKB-SubCell:SL-0168 COQ10B UniProtKB UniProtKB {GO:0005739=GO_REF:0000019, GO:0005743=GO_REF:0000039} Q9H8M1 Coenzyme Q-binding protein COQ10 homolog B, mitochondrial protein 20130413 {GO:0005739=IEA, GO:0005743=IEA} mitochondrial inner membrane, mitochondrion Human UniProtKB-SubCell:SL-0168 COQ2 Reactome UniProtKB {GO:0005739=PMID:15153069, GO:0006744=Reactome:REACT_160111, GO:0047293=GO_REF:0000003, GO:0005743=Reactome:REACT_160153, GO:0044281=Reactome:REACT_111217, GO:0016021=PMID:15153069, GO:0008299=GO_REF:0000037, GO:0006071=PMID:15153069, GO:0002083=GO_REF:0000003, GO:0004659=GO_REF:0000002} Q96H96 4-hydroxybenzoate polyprenyltransferase, mitochondrial protein 20130301 {GO:0005739=RCA, GO:0006744=TAS, GO:0047293=IEA, GO:0005743=TAS, GO:0044281=TAS, GO:0016021=RCA, GO:0008299=IEA, GO:0006071=IGI, GO:0002083=IEA, GO:0004659=IEA} glycerol metabolic process, isoprenoid biosynthetic process, small molecule metabolic process, ubiquinone biosynthetic process integral to membrane, mitochondrial inner membrane, mitochondrion 4-hydroxybenzoate decaprenyltransferase activity, 4-hydroxybenzoate nonaprenyltransferase activity, prenyltransferase activity Human COQ4 LIFEdb UniProtKB {GO:0005739=GO_REF:0000054, GO:0006744=GO_REF:0000041, GO:0005743=GO_REF:0000039} Q9Y3A0 Ubiquinone biosynthesis protein COQ4 homolog, mitochondrial protein 20100607 {GO:0005739=IDA, GO:0006744=IEA, GO:0005743=IEA} ubiquinone biosynthetic process mitochondrial inner membrane, mitochondrion Human COQ5 Reactome UniProtKB {GO:0005739=GO_REF:0000039, GO:0006744=Reactome:REACT_160111, GO:0008168=GO_REF:0000037, GO:0044281=Reactome:REACT_111217} Q5HYK3 2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial protein 20130301 {GO:0005739=IEA, GO:0006744=TAS, GO:0008168=IEA, GO:0044281=TAS} small molecule metabolic process, ubiquinone biosynthetic process mitochondrion methyltransferase activity Human COQ6 LIFEdb UniProtKB {GO:0005739=GO_REF:0000054, GO:0006744=Reactome:REACT_160111, GO:0005794=GO_REF:0000039, GO:0050660=GO_REF:0000002, GO:0016709=GO_REF:0000002, GO:0044281=Reactome:REACT_111217, GO:0042995=GO_REF:0000039} Q9Y2Z9 Ubiquinone biosynthesis monooxygenase COQ6 protein 20100607 {GO:0005739=IDA, GO:0006744=TAS, GO:0005794=IEA, GO:0050660=IEA, GO:0016709=IEA, GO:0044281=TAS, GO:0042995=IEA} small molecule metabolic process, ubiquinone biosynthetic process Golgi apparatus, cell projection, mitochondrion flavin adenine dinucleotide binding, oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen Human COQ7 Reactome UniProtKB {GO:0005743=GO_REF:0000039, GO:0046914=GO_REF:0000002, GO:0005634=GO_REF:0000054, GO:0044281=Reactome:REACT_111217, GO:0001701=GO_REF:0000019, GO:0008340=GO_REF:0000019, GO:0001841=GO_REF:0000019, GO:0005739=GO_REF:0000019, GO:0006744=Reactome:REACT_160111, GO:0070584=GO_REF:0000019, GO:0042775=GO_REF:0000019, GO:0016491=GO_REF:0000002, GO:0034599=GO_REF:0000019, GO:0001306=GO_REF:0000019, GO:0055114=GO_REF:0000002, GO:0022008=GO_REF:0000019} Q99807 Ubiquinone biosynthesis protein COQ7 homolog protein 20120315 {GO:0005743=IEA, GO:0046914=IEA, GO:0005634=IDA, GO:0044281=TAS, GO:0001701=IEA, GO:0008340=IEA, GO:0001841=IEA, GO:0005739=IEA, GO:0006744=TAS, GO:0070584=IEA, GO:0042775=IEA, GO:0016491=IEA, GO:0034599=IEA, GO:0001306=IEA, GO:0055114=IEA, GO:0022008=IEA} age-dependent response to oxidative stress, cellular response to oxidative stress, determination of adult lifespan, in utero embryonic development, mitochondrial ATP synthesis coupled electron transport, mitochondrion morphogenesis, neural tube formation, neurogenesis, oxidation-reduction process, small molecule metabolic process, ubiquinone biosynthetic process mitochondrial inner membrane, mitochondrion, nucleus oxidoreductase activity, transition metal ion binding Human COQ9 UniPathway UniProtKB {GO:0005739=GO_REF:0000039, GO:0006744=GO_REF:0000041} O75208 Ubiquinone biosynthesis protein COQ9, mitochondrial protein 20130413 {GO:0005739=IEA, GO:0006744=IEA} ubiquinone biosynthetic process mitochondrion Human UniPathway:UPA00232 CORIN UniProtKB UniProtKB {GO:0007565=PMID:22437503, GO:0004252=PMID:10880574, GO:0009986=GO_REF:0000019, GO:0005886=GO_REF:0000039, GO:0005576=GO_REF:0000039, GO:0016020=GO_REF:0000002, GO:0016486=PMID:10880574, GO:0008217=GO_REF:0000024, GO:0006508=GO_REF:0000037, GO:0035813=GO_REF:0000024, GO:0016021=GO_REF:0000037, GO:0003050=GO_REF:0000024, GO:0070008=GO_REF:0000002, GO:0005044=GO_REF:0000002} Q9Y5Q5 Atrial natriuretic peptide-converting enzyme protein 20120430 {GO:0007565=IMP, GO:0004252=IDA, GO:0009986=IEA, GO:0005886=IEA, GO:0005576=IEA, GO:0016020=IEA, GO:0016486=IDA, GO:0008217=ISS, GO:0006508=IEA, GO:0035813=ISS, GO:0016021=IEA, GO:0003050=ISS, GO:0070008=IEA, GO:0005044=IEA} female pregnancy, peptide hormone processing, proteolysis, regulation of blood pressure, regulation of renal sodium excretion, regulation of systemic arterial blood pressure by atrial natriuretic peptide cell surface, extracellular region, integral to membrane, membrane, plasma membrane scavenger receptor activity, serine-type endopeptidase activity, serine-type exopeptidase activity Human UniProtKB:Q9Z319 CORO1A IntAct UniProtKB {GO:0008092=GO_REF:0000024, GO:0005515=PMID:21988832, GO:0006909=PMID:17442961, GO:0030036=PMID:17442961, GO:0008360=GO_REF:0000033, GO:0005884=PMID:15800061, GO:0006928=PMID:17341475, GO:0005634=PMID:17341475, GO:0042803=PMID:15601263, GO:0042802=GO_REF:0000019, GO:0051015=PMID:15601263, GO:0030833=GO_REF:0000019, GO:0048873=GO_REF:0000019, GO:0042102=GO_REF:0000019, GO:0030670=GO_REF:0000039, GO:0007015=GO_REF:0000019, GO:0006816=GO_REF:0000019, GO:0034097=GO_REF:0000019, GO:0043029=GO_REF:0000019, GO:0031252=GO_REF:0000019, GO:0001772=GO_REF:0000019, GO:0030335=GO_REF:0000019, GO:0030595=GO_REF:0000033, GO:0031589=PMID:17442961, GO:0001845=PMID:12132654, GO:0008022=PMID:9365277, GO:0050918=PMID:17442961, GO:0043234=PMID:11094157, GO:0032796=GO_REF:0000033, GO:0045087=PMID:17341475, GO:0051126=PMID:17442961, GO:0030864=PMID:15800061, GO:0043548=PMID:11094157} P31146 Coronin-1A protein 20130415 {GO:0008092=ISS, GO:0005515=IPI, GO:0006909=IMP, GO:0030036=IMP, GO:0008360=IBA, GO:0005884=IDA, GO:0006928=NAS, GO:0005634=IDA, GO:0042803=IDA, GO:0042802=IEA, GO:0051015=IDA, GO:0030833=IEA, GO:0048873=IEA, GO:0042102=IEA, GO:0030670=IEA, GO:0007015=IEA, GO:0006816=IEA, GO:0034097=IEA, GO:0043029=IEA, GO:0031252=IEA, GO:0001772=IEA, GO:0030335=IEA, GO:0030595=IBA, GO:0031589=IMP, GO:0001845=IMP, GO:0008022=IPI, GO:0050918=IDA, GO:0043234=IDA, GO:0032796=IBA, GO:0045087=NAS, GO:0051126=IDA, GO:0030864=IDA, GO:0043548=IDA} T cell homeostasis, actin cytoskeleton organization, actin filament organization, calcium ion transport, cell-substrate adhesion, cellular component movement, homeostasis of number of cells within a tissue, innate immune response, leukocyte chemotaxis, negative regulation of actin nucleation, phagocytosis, phagolysosome assembly, positive chemotaxis, positive regulation of T cell proliferation, positive regulation of cell migration, regulation of actin filament polymerization, regulation of cell shape, response to cytokine stimulus, uropod organization actin filament, cell leading edge, cortical actin cytoskeleton, immunological synapse, nucleus, phagocytic vesicle membrane, protein complex actin filament binding, cytoskeletal protein binding, identical protein binding, phosphatidylinositol 3-kinase binding, protein C-terminus binding, protein binding, protein homodimerization activity Human UniProtKB:P40763 CORO1B IntAct UniProtKB {GO:0005515=PMID:17350576, GO:0005737=GO_REF:0000037, GO:0051015=GO_REF:0000033, GO:0030036=GO_REF:0000033, GO:0015629=GO_REF:0000033} Q9BR76 Coronin-1B protein 20130415 {GO:0005515=IPI, GO:0005737=IEA, GO:0051015=IBA, GO:0030036=IBA, GO:0015629=IBA} actin cytoskeleton organization actin cytoskeleton, cytoplasm actin filament binding, protein binding Human UniProtKB:Q8WYL5 CORO1C PINC UniProtKB {GO:0006909=PMID:9778037, GO:0007165=PMID:9778037, GO:0051015=GO_REF:0000033, GO:0030036=GO_REF:0000033, GO:0015629=GO_REF:0000033} Q9ULV4 Coronin-1C protein 20030904 {GO:0006909=TAS, GO:0007165=TAS, GO:0051015=IBA, GO:0030036=IBA, GO:0015629=IBA} actin cytoskeleton organization, phagocytosis, signal transduction actin cytoskeleton actin filament binding Human CORO2A PINC UniProtKB {GO:0035556=PMID:8985118, GO:0051015=GO_REF:0000033, GO:0030036=GO_REF:0000033, GO:0017053=PMID:12628926, GO:0015629=GO_REF:0000033} Q92828 Coronin-2A protein 20030904 {GO:0035556=TAS, GO:0051015=IBA, GO:0030036=IBA, GO:0017053=IDA, GO:0015629=IBA} actin cytoskeleton organization, intracellular signal transduction actin cytoskeleton, transcriptional repressor complex actin filament binding Human CORO2B UniProtKB UniProtKB {GO:0005737=GO_REF:0000037, GO:0051015=GO_REF:0000033, GO:0030036=PMID:10224093, GO:0016020=PMID:10224093, GO:0003779=PMID:10224093, GO:0015629=GO_REF:0000033} Q9UQ03 Coronin-2B protein 20030403 {GO:0005737=IEA, GO:0051015=IBA, GO:0030036=NAS, GO:0016020=NAS, GO:0003779=NAS, GO:0015629=IBA} actin cytoskeleton organization actin cytoskeleton, cytoplasm, membrane actin binding, actin filament binding Human CORO7 UniProtKB UniProtKB {GO:0051015=GO_REF:0000033, GO:0030036=GO_REF:0000033, GO:0005794=GO_REF:0000024, GO:0000139=GO_REF:0000039, GO:0016023=GO_REF:0000039, GO:0016021=GO_REF:0000024, GO:0015629=GO_REF:0000033, GO:0005829=GO_REF:0000039} P57737 Coronin-7 protein 20041201 {GO:0051015=IRD, GO:0030036=IRD, GO:0005794=ISS, GO:0000139=IEA, GO:0016023=IEA, GO:0016021=ISS, GO:0015629=IRD, GO:0005829=IEA} actin cytoskeleton organization Golgi apparatus, Golgi membrane, actin cytoskeleton, cytoplasmic membrane-bounded vesicle, cytosol, integral to membrane actin filament binding Human UniProtKB:Q9D2V7 CORT UniProtKB UniProtKB {GO:0001664=PMID:12915402, GO:0007268=PMID:9125122, GO:0005184=PMID:9125122, GO:0007193=PMID:9125122, GO:0005615=PMID:9125122} O00230 Cortistatin protein 20120802 {GO:0001664=IPI, GO:0007268=NAS, GO:0005184=IDA, GO:0007193=IDA, GO:0005615=NAS} adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway, synaptic transmission extracellular space G-protein coupled receptor binding, neuropeptide hormone activity Human COTL1 IntAct UniProtKB {GO:0005515=PMID:11297527, GO:0005622=GO_REF:0000002, GO:0008150=GO_REF:0000015, GO:0031965=GO_REF:0000039, GO:0005737=GO_REF:0000037, GO:0050832=GO_REF:0000019, GO:0003779=PMID:11583571, GO:0005575=GO_REF:0000015, GO:0005856=GO_REF:0000039, GO:0019899=PMID:11297527} Q14019 Coactosin-like protein protein 20130415 {GO:0005515=IPI, GO:0005622=IEA, GO:0008150=ND, GO:0031965=IEA, GO:0005737=IEA, GO:0050832=IEA, GO:0003779=IDA, GO:0005575=ND, GO:0005856=IEA, GO:0019899=IPI} biological_process, defense response to fungus cellular_component, cytoplasm, cytoskeleton, intracellular, nuclear membrane actin binding, enzyme binding, protein binding Human UniProtKB:P09917 COX11 PINC UniProtKB {GO:0005739=PMID:9878253, GO:0008535=PMID:9878253, GO:0007585=PMID:9878253, GO:0005507=GO_REF:0000002, GO:0004129=PMID:9878253, GO:0005743=GO_REF:0000039, GO:0009055=PMID:9878253, GO:0016021=GO_REF:0000037} Q9Y6N1 Cytochrome c oxidase assembly protein COX11, mitochondrial protein 20030904 {GO:0005739=TAS, GO:0008535=TAS, GO:0007585=TAS, GO:0005507=IEA, GO:0004129=TAS, GO:0005743=IEA, GO:0009055=TAS, GO:0016021=IEA} respiratory chain complex IV assembly, respiratory gaseous exchange integral to membrane, mitochondrial inner membrane, mitochondrion copper ion binding, cytochrome-c oxidase activity, electron carrier activity Human COX15 BHF-UCL UniProtKB {GO:0005739=PMID:9878253, GO:0045333=PMID:12474143, GO:0005746=PMID:9878253, GO:0008535=PMID:12474143, GO:0007585=PMID:9878253, GO:0006123=PMID:12474143, GO:0004129=PMID:12474143, GO:0016021=GO_REF:0000037, GO:0016627=GO_REF:0000002, GO:0006784=PMID:12474143, GO:0055114=PMID:9878253} Q7KZN9 Cytochrome c oxidase assembly protein COX15 homolog protein 20130214 {GO:0005739=IDA, GO:0045333=IC, GO:0005746=TAS, GO:0008535=IMP, GO:0007585=TAS, GO:0006123=IC, GO:0004129=IGI, GO:0016021=IEA, GO:0016627=IEA, GO:0006784=IGI, GO:0055114=TAS} cellular respiration, heme a biosynthetic process, mitochondrial electron transport, cytochrome c to oxygen, oxidation-reduction process, respiratory chain complex IV assembly, respiratory gaseous exchange integral to membrane, mitochondrial respiratory chain, mitochondrion cytochrome-c oxidase activity, oxidoreductase activity, acting on the CH-CH group of donors Human COX17 PINC UniProtKB {GO:0007507=GO_REF:0000019, GO:0005758=GO_REF:0000039, GO:0005737=PMID:9050918, GO:0005507=PMID:9050918, GO:0007420=GO_REF:0000019, GO:0006091=PMID:9050918, GO:0016531=GO_REF:0000002, GO:0006825=GO_REF:0000002} Q14061 Cytochrome c oxidase copper chaperone protein 20030904 {GO:0007507=IEA, GO:0005758=IEA, GO:0005737=TAS, GO:0005507=TAS, GO:0007420=IEA, GO:0006091=TAS, GO:0016531=IEA, GO:0006825=IEA} brain development, copper ion transport, generation of precursor metabolites and energy, heart development cytoplasm, mitochondrial intermembrane space copper chaperone activity, copper ion binding Human COX4I1 InterPro UniProtKB {GO:0005739=GO_REF:0000052, GO:0022904=Reactome:REACT_22393, GO:0007584=GO_REF:0000019, GO:0004129=GO_REF:0000002, GO:0005743=Reactome:REACT_6149, GO:0005634=GO_REF:0000052, GO:0044281=Reactome:REACT_111217, GO:0006091=PMID:2157630} Q86WV2 COX4I1 protein protein 20130413 {GO:0005739=IDA, GO:0022904=TAS, GO:0007584=IEA, GO:0004129=IEA, GO:0005743=TAS, GO:0005634=IDA, GO:0044281=TAS, GO:0006091=TAS} generation of precursor metabolites and energy, respiratory electron transport chain, response to nutrient, small molecule metabolic process mitochondrial inner membrane, mitochondrion, nucleus cytochrome-c oxidase activity Human InterPro:IPR004203 COX4I2 UniProtKB UniProtKB {GO:0045333=PMID:11911854, GO:0004129=PMID:11311561, GO:0006091=PMID:11311561, GO:0005751=PMID:11311561, GO:0055114=PMID:11311561} Q96KJ9 Cytochrome c oxidase subunit 4 isoform 2, mitochondrial protein 20020730 {GO:0045333=NAS, GO:0004129=IDA, GO:0006091=NAS, GO:0005751=IC, GO:0055114=NAS} cellular respiration, generation of precursor metabolites and energy, oxidation-reduction process mitochondrial respiratory chain complex IV cytochrome-c oxidase activity Human COX5A Reactome UniProtKB {GO:0022904=Reactome:REACT_22393, GO:0004129=GO_REF:0000002, GO:0005743=Reactome:REACT_6149, GO:0009055=PMID:2853101, GO:0044281=Reactome:REACT_111217, GO:0046872=GO_REF:0000037} P20674 Cytochrome c oxidase subunit 5A, mitochondrial protein 20050517 {GO:0022904=TAS, GO:0004129=IEA, GO:0005743=TAS, GO:0009055=TAS, GO:0044281=TAS, GO:0046872=IEA} respiratory electron transport chain, small molecule metabolic process mitochondrial inner membrane cytochrome-c oxidase activity, electron carrier activity, metal ion binding Human COX5B HPA UniProtKB {GO:0005739=GO_REF:0000052, GO:0022904=Reactome:REACT_22393, GO:0007585=PMID:1646156, GO:0004129=GO_REF:0000002, GO:0005743=Reactome:REACT_6149, GO:0044281=Reactome:REACT_111217, GO:0046872=GO_REF:0000037} P10606 Cytochrome c oxidase subunit 5B, mitochondrial protein 20101115 {GO:0005739=IDA, GO:0022904=TAS, GO:0007585=TAS, GO:0004129=IEA, GO:0005743=TAS, GO:0044281=TAS, GO:0046872=IEA} respiratory electron transport chain, respiratory gaseous exchange, small molecule metabolic process mitochondrial inner membrane, mitochondrion cytochrome-c oxidase activity, metal ion binding Human COX6A1 Reactome UniProtKB {GO:0022904=Reactome:REACT_22393, GO:0004129=GO_REF:0000002, GO:0005743=Reactome:REACT_6149, GO:0044281=Reactome:REACT_111217, GO:0006091=PMID:2549515, GO:0005751=GO_REF:0000002} P12074 Cytochrome c oxidase subunit 6A1, mitochondrial protein 20050517 {GO:0022904=TAS, GO:0004129=IEA, GO:0005743=TAS, GO:0044281=TAS, GO:0006091=TAS, GO:0005751=IEA} generation of precursor metabolites and energy, respiratory electron transport chain, small molecule metabolic process mitochondrial inner membrane, mitochondrial respiratory chain complex IV cytochrome-c oxidase activity Human COX6A2 PINC UniProtKB {GO:0004129=GO_REF:0000002, GO:0006091=PMID:9284905, GO:0005751=GO_REF:0000002} Q02221 Cytochrome c oxidase subunit 6A2, mitochondrial protein 20030904 {GO:0004129=IEA, GO:0006091=TAS, GO:0005751=IEA} generation of precursor metabolites and energy mitochondrial respiratory chain complex IV cytochrome-c oxidase activity Human COX6B1 HPA UniProtKB {GO:0022904=Reactome:REACT_22393, GO:0005739=GO_REF:0000052, GO:0005758=GO_REF:0000039, GO:0004129=PMID:2172092, GO:0005743=Reactome:REACT_6149, GO:0044281=Reactome:REACT_111217, GO:0055114=GO_REF:0000029} P14854 Cytochrome c oxidase subunit 6B1 protein 20080205 {GO:0022904=TAS, GO:0005739=IDA, GO:0005758=IEA, GO:0004129=NAS, GO:0005743=TAS, GO:0044281=TAS, GO:0055114=NAS} oxidation-reduction process, respiratory electron transport chain, small molecule metabolic process mitochondrial inner membrane, mitochondrial intermembrane space, mitochondrion cytochrome-c oxidase activity Human COX6C Reactome UniProtKB {GO:0022904=Reactome:REACT_22393, GO:0004129=GO_REF:0000002, GO:0005743=Reactome:REACT_6149, GO:0044281=Reactome:REACT_111217, GO:0006091=PMID:2849755, GO:0016021=GO_REF:0000037} P09669 Cytochrome c oxidase subunit 6C protein 20050517 {GO:0022904=TAS, GO:0004129=IEA, GO:0005743=TAS, GO:0044281=TAS, GO:0006091=TAS, GO:0016021=IEA} generation of precursor metabolites and energy, respiratory electron transport chain, small molecule metabolic process integral to membrane, mitochondrial inner membrane cytochrome-c oxidase activity Human COX7A2 InterPro UniProtKB {GO:0005746=GO_REF:0000002, GO:0004129=GO_REF:0000002, GO:0009055=GO_REF:0000002} P14406 Cytochrome c oxidase subunit 7A2, mitochondrial protein 20130413 {GO:0005746=IEA, GO:0004129=IEA, GO:0009055=IEA} mitochondrial respiratory chain cytochrome-c oxidase activity, electron carrier activity Human InterPro:IPR003177 COX7A2L Reactome UniProtKB {GO:0022904=Reactome:REACT_22393, GO:0005746=GO_REF:0000002, GO:0004129=GO_REF:0000002, GO:0005743=Reactome:REACT_6149, GO:0009055=GO_REF:0000002, GO:0044281=Reactome:REACT_111217} O14548 Cytochrome c oxidase subunit 7A-related protein, mitochondrial protein 20050517 {GO:0022904=TAS, GO:0005746=IEA, GO:0004129=IEA, GO:0005743=TAS, GO:0009055=IEA, GO:0044281=TAS} respiratory electron transport chain, small molecule metabolic process mitochondrial inner membrane, mitochondrial respiratory chain cytochrome-c oxidase activity, electron carrier activity Human COX7B Reactome UniProtKB {GO:0022904=Reactome:REACT_22393, GO:0005746=GO_REF:0000002, GO:0004129=GO_REF:0000002, GO:0005743=Reactome:REACT_6149, GO:0044281=Reactome:REACT_111217, GO:0016021=GO_REF:0000037, GO:0007417=PMID:23122588} P24311 Cytochrome c oxidase subunit 7B, mitochondrial protein 20050517 {GO:0022904=TAS, GO:0005746=IEA, GO:0004129=IEA, GO:0005743=TAS, GO:0044281=TAS, GO:0016021=IEA, GO:0007417=IMP} central nervous system development, respiratory electron transport chain, small molecule metabolic process integral to membrane, mitochondrial inner membrane, mitochondrial respiratory chain cytochrome-c oxidase activity Human COX7C Reactome UniProtKB {GO:0022904=Reactome:REACT_22393, GO:0004129=GO_REF:0000002, GO:0005743=Reactome:REACT_6149, GO:0044281=Reactome:REACT_111217, GO:0006091=PMID:2155413, GO:0016021=GO_REF:0000037} P15954 Cytochrome c oxidase subunit 7C, mitochondrial protein 20050517 {GO:0022904=TAS, GO:0004129=IEA, GO:0005743=TAS, GO:0044281=TAS, GO:0006091=TAS, GO:0016021=IEA} generation of precursor metabolites and energy, respiratory electron transport chain, small molecule metabolic process integral to membrane, mitochondrial inner membrane cytochrome-c oxidase activity Human COX8A Reactome UniProtKB {GO:0022904=Reactome:REACT_22393, GO:0004129=GO_REF:0000002, GO:0005743=Reactome:REACT_6149, GO:0044281=Reactome:REACT_111217, GO:0006091=PMID:2543673, GO:0016021=GO_REF:0000037} P10176 Cytochrome c oxidase subunit 8A, mitochondrial protein 20050517 {GO:0022904=TAS, GO:0004129=IEA, GO:0005743=TAS, GO:0044281=TAS, GO:0006091=TAS, GO:0016021=IEA} generation of precursor metabolites and energy, respiratory electron transport chain, small molecule metabolic process integral to membrane, mitochondrial inner membrane cytochrome-c oxidase activity Human CP BHF-UCL UniProtKB {GO:0006879=Reactome:REACT_25060, GO:0004322=GO_REF:0000003, GO:0005507=GO_REF:0000019, GO:0051087=PMID:19996109, GO:0005576=Reactome:REACT_25098, GO:0005615=PMID:19996109, GO:0055085=Reactome:REACT_19118, GO:0006825=GO_REF:0000037} P00450 Ceruloplasmin protein 20100113 {GO:0006879=TAS, GO:0004322=IEA, GO:0005507=IEA, GO:0051087=IPI, GO:0005576=TAS, GO:0005615=IDA, GO:0055085=TAS, GO:0006825=IEA} cellular iron ion homeostasis, copper ion transport, transmembrane transport extracellular region, extracellular space chaperone binding, copper ion binding, ferroxidase activity Human UniProtKB:P10909 CPA1 UniProtKB UniProtKB {GO:0006508=GO_REF:0000019, GO:0008270=GO_REF:0000002, GO:0005615=PMID:2920728, GO:0004181=GO_REF:0000002} P15085 Carboxypeptidase A1 protein 20060508 {GO:0006508=IEA, GO:0008270=IEA, GO:0005615=IDA, GO:0004181=IEA} proteolysis extracellular space metallocarboxypeptidase activity, zinc ion binding Human CPA4 UniProtKB UniProtKB {GO:0016573=PMID:10383164, GO:0004180=GO_REF:0000002, GO:0006508=GO_REF:0000029, GO:0005576=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0005575=GO_REF:0000015, GO:0004181=PMID:10383164} Q9UI42 Carboxypeptidase A4 protein 20061026 {GO:0016573=NAS, GO:0004180=IEA, GO:0006508=NAS, GO:0005576=IEA, GO:0008270=IEA, GO:0005575=ND, GO:0004181=NAS} histone acetylation, proteolysis cellular_component, extracellular region carboxypeptidase activity, metallocarboxypeptidase activity, zinc ion binding Human CPAMD8 UniProtKB UniProtKB {GO:0005886=GO_REF:0000039, GO:0004866=GO_REF:0000002, GO:0004867=GO_REF:0000037, GO:0005576=GO_REF:0000002, GO:0005615=GO_REF:0000002} Q8IZJ3 C3 and PZP-like alpha-2-macroglobulin domain-containing protein 8 protein 20130413 {GO:0005886=IEA, GO:0004866=IEA, GO:0004867=IEA, GO:0005576=IEA, GO:0005615=IEA} extracellular region, extracellular space, plasma membrane endopeptidase inhibitor activity, serine-type endopeptidase inhibitor activity Human UniProtKB-SubCell:SL-0039 CPB1 PINC UniProtKB {GO:0006508=GO_REF:0000037, GO:0004180=PMID:1370825, GO:0005576=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0004181=GO_REF:0000002} P15086 Carboxypeptidase B protein 20030904 {GO:0006508=IEA, GO:0004180=TAS, GO:0005576=IEA, GO:0008270=IEA, GO:0004181=IEA} proteolysis extracellular region carboxypeptidase activity, metallocarboxypeptidase activity, zinc ion binding Human CPB2 ENSEMBL UniProtKB {GO:0009408=GO_REF:0000019, GO:0007596=GO_REF:0000037, GO:0042493=GO_REF:0000019, GO:0006508=GO_REF:0000019, GO:0051918=GO_REF:0000019, GO:0008270=GO_REF:0000002, GO:0042730=GO_REF:0000019, GO:0005615=GO_REF:0000019, GO:0004181=GO_REF:0000002} Q96IY4 Carboxypeptidase B2 protein 20130413 {GO:0009408=IEA, GO:0007596=IEA, GO:0042493=IEA, GO:0006508=IEA, GO:0051918=IEA, GO:0008270=IEA, GO:0042730=IEA, GO:0005615=IEA, GO:0004181=IEA} blood coagulation, fibrinolysis, negative regulation of fibrinolysis, proteolysis, response to drug, response to heat extracellular space metallocarboxypeptidase activity, zinc ion binding Human Ensembl:ENSRNOP00000014909 CPD PINC UniProtKB {GO:0004185=GO_REF:0000002, GO:0016020=PMID:9064476, GO:0006508=GO_REF:0000037, GO:0008270=GO_REF:0000002, GO:0016021=GO_REF:0000037, GO:0004181=GO_REF:0000002} O75976 Carboxypeptidase D protein 20030904 {GO:0004185=IEA, GO:0016020=TAS, GO:0006508=IEA, GO:0008270=IEA, GO:0016021=IEA, GO:0004181=IEA} proteolysis integral to membrane, membrane metallocarboxypeptidase activity, serine-type carboxypeptidase activity, zinc ion binding Human CPE BHF-UCL UniProtKB {GO:0005794=PMID:19166515, GO:0005886=PMID:9019408, GO:0005576=GO_REF:0000039, GO:0005634=GO_REF:0000039, GO:0003214=PMID:19593212, GO:0072657=PMID:19166515, GO:0042043=PMID:19166515, GO:0007218=PMID:2334405, GO:0008152=PMID:7663508, GO:0006508=GO_REF:0000037, GO:0004180=PMID:9019408, GO:0008270=GO_REF:0000002, GO:0030070=GO_REF:0000019, GO:0050839=PMID:19166515, GO:0044267=Reactome:REACT_17015, GO:0006464=PMID:2334405, GO:0030658=GO_REF:0000039, GO:0030667=Reactome:REACT_15374, GO:0004181=GO_REF:0000002} P16870 Carboxypeptidase E protein 20100819 {GO:0005794=IDA, GO:0005886=TAS, GO:0005576=IEA, GO:0005634=IEA, GO:0003214=IMP, GO:0072657=IDA, GO:0042043=IPI, GO:0007218=NAS, GO:0008152=TAS, GO:0006508=IEA, GO:0004180=TAS, GO:0008270=IEA, GO:0030070=IEA, GO:0050839=IPI, GO:0044267=TAS, GO:0006464=NAS, GO:0030658=IEA, GO:0030667=TAS, GO:0004181=IEA} cardiac left ventricle morphogenesis, cellular protein metabolic process, cellular protein modification process, insulin processing, metabolic process, neuropeptide signaling pathway, protein localization to membrane, proteolysis Golgi apparatus, extracellular region, nucleus, plasma membrane, secretory granule membrane, transport vesicle membrane carboxypeptidase activity, cell adhesion molecule binding, metallocarboxypeptidase activity, neurexin family protein binding, zinc ion binding Human CPEB1 UniProtKB UniProtKB {GO:0006397=GO_REF:0000037, GO:0030054=GO_REF:0000037, GO:0005886=GO_REF:0000037, GO:0000166=GO_REF:0000002, GO:0000932=GO_REF:0000039, GO:0045211=GO_REF:0000037, GO:0003723=GO_REF:0000037, GO:0014069=GO_REF:0000039, GO:0003676=GO_REF:0000002, GO:0006417=GO_REF:0000037} Q9BZB8 Cytoplasmic polyadenylation element-binding protein 1 protein 20130413 {GO:0006397=IEA, GO:0030054=IEA, GO:0005886=IEA, GO:0000166=IEA, GO:0000932=IEA, GO:0045211=IEA, GO:0003723=IEA, GO:0014069=IEA, GO:0003676=IEA, GO:0006417=IEA} mRNA processing, regulation of translation cell junction, cytoplasmic mRNA processing body, plasma membrane, postsynaptic density, postsynaptic membrane RNA binding, nucleic acid binding, nucleotide binding Human UniProtKB-SubCell:SL-0297 CPEB4 ENSEMBL UniProtKB {GO:0000166=GO_REF:0000002, GO:0003723=GO_REF:0000019, GO:0045202=GO_REF:0000019, GO:0003676=GO_REF:0000002} Q17RY0 Cytoplasmic polyadenylation element-binding protein 4 protein 20130413 {GO:0000166=IEA, GO:0003723=IEA, GO:0045202=IEA, GO:0003676=IEA} synapse RNA binding, nucleic acid binding, nucleotide binding Human Ensembl:ENSMUSP00000020543 CPLX1 Reactome UniProtKB {GO:0019905=GO_REF:0000002, GO:0005326=GO_REF:0000019, GO:0045202=GO_REF:0000019, GO:0007268=Reactome:REACT_13685, GO:0006887=PMID:7553862, GO:0014047=Reactome:REACT_12591, GO:0016079=GO_REF:0000019, GO:0007269=Reactome:REACT_13723, GO:0030425=GO_REF:0000019, GO:0005829=Reactome:REACT_23973, GO:0043025=GO_REF:0000019, GO:0006836=GO_REF:0000002, GO:0017075=GO_REF:0000019, GO:0070032=GO_REF:0000019, GO:0030073=GO_REF:0000019} O14810 Complexin-1 protein 20130213 {GO:0019905=IEA, GO:0005326=IEA, GO:0045202=IEA, GO:0007268=TAS, GO:0006887=TAS, GO:0014047=TAS, GO:0016079=IEA, GO:0007269=TAS, GO:0030425=IEA, GO:0005829=TAS, GO:0043025=IEA, GO:0006836=IEA, GO:0017075=IEA, GO:0070032=IEA, GO:0030073=IEA} exocytosis, glutamate secretion, insulin secretion, neurotransmitter secretion, neurotransmitter transport, synaptic transmission, synaptic vesicle exocytosis cytosol, dendrite, neuronal cell body, synapse, synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex neurotransmitter transporter activity, syntaxin binding, syntaxin-1 binding Human CPLX2 PINC UniProtKB {GO:0019905=GO_REF:0000002, GO:0043303=GO_REF:0000037, GO:0031201=GO_REF:0000019, GO:0045202=GO_REF:0000019, GO:0016079=GO_REF:0000019, GO:0030425=GO_REF:0000019, GO:0030154=GO_REF:0000037, GO:0006904=PMID:7553862, GO:0007399=GO_REF:0000037, GO:0005829=GO_REF:0000039, GO:0031915=GO_REF:0000024, GO:0043025=GO_REF:0000019, GO:0006836=GO_REF:0000002, GO:0017075=GO_REF:0000019} Q6PUV4 Complexin-2 protein 20040715 {GO:0019905=IEA, GO:0043303=IEA, GO:0031201=IEA, GO:0045202=IEA, GO:0016079=IEA, GO:0030425=IEA, GO:0030154=IEA, GO:0006904=TAS, GO:0007399=IEA, GO:0005829=IEA, GO:0031915=ISS, GO:0043025=IEA, GO:0006836=IEA, GO:0017075=IEA} cell differentiation, mast cell degranulation, nervous system development, neurotransmitter transport, positive regulation of synaptic plasticity, synaptic vesicle exocytosis, vesicle docking involved in exocytosis SNARE complex, cytosol, dendrite, neuronal cell body, synapse syntaxin binding, syntaxin-1 binding Human CPM HPA UniProtKB {GO:0005737=GO_REF:0000052, GO:0005886=GO_REF:0000052, GO:0004180=PMID:7797563, GO:0005730=GO_REF:0000052, GO:0006508=GO_REF:0000037, GO:0005634=GO_REF:0000052, GO:0008270=GO_REF:0000002, GO:0031225=GO_REF:0000037, GO:0009653=PMID:7797563, GO:0004181=GO_REF:0000002} P14384 Carboxypeptidase M protein 20101115 {GO:0005737=IDA, GO:0005886=IDA, GO:0004180=TAS, GO:0005730=IDA, GO:0006508=IEA, GO:0005634=IDA, GO:0008270=IEA, GO:0031225=IEA, GO:0009653=TAS, GO:0004181=IEA} anatomical structure morphogenesis, proteolysis anchored to membrane, cytoplasm, nucleolus, nucleus, plasma membrane carboxypeptidase activity, metallocarboxypeptidase activity, zinc ion binding Human CPN1 UniProtKB UniProtKB {GO:0006508=GO_REF:0000019, GO:0051384=GO_REF:0000019, GO:0008270=GO_REF:0000002, GO:0005615=GO_REF:0000039, GO:0004181=GO_REF:0000002} P15169 Carboxypeptidase N catalytic chain protein 20130413 {GO:0006508=IEA, GO:0051384=IEA, GO:0008270=IEA, GO:0005615=IEA, GO:0004181=IEA} proteolysis, response to glucocorticoid stimulus extracellular space metallocarboxypeptidase activity, zinc ion binding Human UniProtKB-SubCell:SL-0112 CPN2 GOC UniProtKB {GO:0050790=PMID:2378615, GO:0050821=PMID:2378615, GO:0030234=PMID:2378615, GO:0005576=PMID:2378615} P22792 Carboxypeptidase N subunit 2 protein 20130413 {GO:0050790=NAS, GO:0050821=NAS, GO:0030234=NAS, GO:0005576=NAS} protein stabilization, regulation of catalytic activity extracellular region enzyme regulator activity Human CPNE1 HPA UniProtKB {GO:0005544=PMID:9430674, GO:0006629=PMID:9430674, GO:0005215=PMID:9430674, GO:0005730=GO_REF:0000052, GO:0001786=PMID:9430674, GO:0005634=GO_REF:0000052, GO:0016192=PMID:9430674} Q99829 Copine-1 protein 20120912 {GO:0005544=TAS, GO:0006629=TAS, GO:0005215=TAS, GO:0005730=IDA, GO:0001786=IDA, GO:0005634=IDA, GO:0016192=TAS} lipid metabolic process, vesicle-mediated transport nucleolus, nucleus calcium-dependent phospholipid binding, phosphatidylserine binding, transporter activity NOT Human CPNE2 null null {} null null null null {} null null null CPNE3 PINC UniProtKB {GO:0006629=PMID:9430674, GO:0005544=PMID:11041869, GO:0005215=PMID:9430674, GO:0005737=PMID:11041869, GO:0004674=PMID:11041869, GO:0016192=PMID:9430674, GO:0005829=PMID:12949241} O75131 Copine-3 protein 20030904 {GO:0006629=TAS, GO:0005544=TAS, GO:0005215=TAS, GO:0005737=NAS, GO:0004674=IDA, GO:0016192=TAS, GO:0005829=IDA} lipid metabolic process, vesicle-mediated transport cytoplasm, cytosol calcium-dependent phospholipid binding, protein serine/threonine kinase activity, transporter activity Human CPNE4 null null {} null null null null {} null null null CPNE5 ENSEMBL UniProtKB {GO:0043005=GO_REF:0000019, GO:0043025=GO_REF:0000019} Q9HCH3 Copine-5 protein 20130413 {GO:0043005=IEA, GO:0043025=IEA} neuron projection, neuronal cell body Human Ensembl:ENSMUSP00000024805 CPNE6 PINC UniProtKB {GO:0006629=PMID:9645480, GO:0005215=PMID:9645480, GO:0030424=GO_REF:0000019, GO:0016020=GO_REF:0000019, GO:0005509=PMID:9645480, GO:0001786=GO_REF:0000019, GO:0007268=PMID:9645480, GO:0016192=PMID:9645480, GO:0030425=GO_REF:0000019, GO:0007399=PMID:9645480} O95741 Copine-6 protein 20030904 {GO:0006629=TAS, GO:0005215=TAS, GO:0030424=IEA, GO:0016020=IEA, GO:0005509=TAS, GO:0001786=IEA, GO:0007268=TAS, GO:0016192=TAS, GO:0030425=IEA, GO:0007399=TAS} lipid metabolic process, nervous system development, synaptic transmission, vesicle-mediated transport axon, dendrite, membrane calcium ion binding, phosphatidylserine binding, transporter activity Human CPNE7 GOC UniProtKB {GO:0006629=PMID:10534407, GO:0005215=PMID:10534407, GO:0006810=PMID:10534407} Q9UBL6 Copine-7 protein 20130413 {GO:0006629=TAS, GO:0005215=TAS, GO:0006810=TAS} lipid metabolic process, transport transporter activity Human CPNE8 null null {} null null null null {} null null null CPNE9 null null {} null null null null {} null null null CPOX HPA UniProtKB {GO:0010288=GO_REF:0000019, GO:0046685=GO_REF:0000019, GO:0005743=GO_REF:0000019, GO:0044281=Reactome:REACT_111217, GO:0006782=GO_REF:0000041, GO:0042803=PMID:16176984, GO:0006783=Reactome:REACT_9465, GO:0005739=GO_REF:0000052, GO:0005758=Reactome:REACT_9421, GO:0005737=GO_REF:0000052, GO:0051597=GO_REF:0000019, GO:0006778=Reactome:REACT_9431, GO:0006779=GO_REF:0000002, GO:0010039=GO_REF:0000019, GO:0017085=GO_REF:0000019, GO:0004109=Reactome:REACT_9421} P36551 Coproporphyrinogen-III oxidase, mitochondrial protein 20101115 {GO:0010288=IEA, GO:0046685=IEA, GO:0005743=IEA, GO:0044281=TAS, GO:0006782=IEA, GO:0042803=IDA, GO:0006783=TAS, GO:0005739=IDA, GO:0005758=TAS, GO:0005737=IDA, GO:0051597=IEA, GO:0006778=TAS, GO:0006779=IEA, GO:0010039=IEA, GO:0017085=IEA, GO:0004109=TAS} heme biosynthetic process, porphyrin-containing compound biosynthetic process, porphyrin-containing compound metabolic process, protoporphyrinogen IX biosynthetic process, response to arsenic-containing substance, response to insecticide, response to iron ion, response to lead ion, response to methylmercury, small molecule metabolic process cytoplasm, mitochondrial inner membrane, mitochondrial intermembrane space, mitochondrion coproporphyrinogen oxidase activity, protein homodimerization activity Human CPPED1 UniProtKB UniProtKB {GO:0016787=GO_REF:0000037, GO:0046872=GO_REF:0000037} Q9BRF8 Calcineurin-like phosphoesterase domain-containing protein 1 protein 20130413 {GO:0016787=IEA, GO:0046872=IEA} hydrolase activity, metal ion binding Human UniProtKB-KW:KW-0479 CPS1 BHF-UCL UniProtKB {GO:0042645=PMID:18063578, GO:0019240=PMID:14718356, GO:0005515=PMID:12620389, GO:0005743=GO_REF:0000019, GO:0044281=Reactome:REACT_111217, GO:0014075=GO_REF:0000019, GO:0032094=GO_REF:0000019, GO:0010043=GO_REF:0000019, GO:0032403=GO_REF:0000019, GO:0050667=PMID:20031578, GO:0046872=GO_REF:0000002, GO:0072341=PMID:20031578, GO:0034641=Reactome:REACT_13, GO:0005543=GO_REF:0000019, GO:0042594=GO_REF:0000019, GO:0070409=PMID:7416778, GO:0071377=GO_REF:0000019, GO:0045909=PMID:14718356, GO:0005759=Reactome:REACT_1701, GO:0032496=PMID:15897806, GO:0046209=PMID:14718356, GO:0019433=PMID:9711878, GO:0043200=GO_REF:0000019, GO:0055081=GO_REF:0000019, GO:0060416=GO_REF:0000019, GO:0042493=GO_REF:0000019, GO:0005509=GO_REF:0000019, GO:0005730=GO_REF:0000039, GO:0009636=GO_REF:0000019, GO:0004087=PMID:9711878, GO:0005524=GO_REF:0000037, GO:0044344=GO_REF:0000019, GO:0043234=GO_REF:0000019, GO:0004175=GO_REF:0000019, GO:0071400=GO_REF:0000019, GO:0007494=GO_REF:0000019, GO:0000050=PMID:1840546, GO:0006543=GO_REF:0000002, GO:0016595=GO_REF:0000019, GO:0071548=GO_REF:0000019, GO:0071320=GO_REF:0000019, GO:0005980=PMID:9711878, GO:0070365=GO_REF:0000019} P31327 "Carbamoyl-phosphate synthase ""ammonia"", mitochondrial" protein 20090218 {GO:0042645=IDA, GO:0019240=NAS, GO:0005515=IPI, GO:0005743=IEA, GO:0044281=TAS, GO:0014075=IEA, GO:0032094=IEA, GO:0010043=IEA, GO:0032403=IEA, GO:0050667=IDA, GO:0046872=IEA, GO:0072341=IDA, GO:0034641=TAS, GO:0005543=IEA, GO:0042594=IEA, GO:0070409=IMP, GO:0071377=IEA, GO:0045909=IMP, GO:0005759=TAS, GO:0032496=IDA, GO:0046209=IMP, GO:0019433=IMP, GO:0043200=IEA, GO:0055081=IEA, GO:0060416=IEA, GO:0042493=IEA, GO:0005509=IEA, GO:0005730=IEA, GO:0009636=IEA, GO:0004087=IMP, GO:0005524=IEA, GO:0044344=IEA, GO:0043234=IEA, GO:0004175=IEA, GO:0071400=IEA, GO:0007494=IEA, GO:0000050=NAS, GO:0006543=IEA, GO:0016595=IEA, GO:0071548=IEA, GO:0071320=IEA, GO:0005980=IMP, GO:0070365=IEA} anion homeostasis, carbamoyl phosphate biosynthetic process, cellular nitrogen compound metabolic process, cellular response to cAMP, cellular response to fibroblast growth factor stimulus, cellular response to glucagon stimulus, cellular response to oleic acid, citrulline biosynthetic process, glutamine catabolic process, glycogen catabolic process, hepatocyte differentiation, homocysteine metabolic process, midgut development, nitric oxide metabolic process, positive regulation of vasodilation, response to amine stimulus, response to amino acid stimulus, response to dexamethasone stimulus, response to drug, response to food, response to growth hormone stimulus, response to lipopolysaccharide, response to starvation, response to toxic substance, response to zinc ion, small molecule metabolic process, triglyceride catabolic process, urea cycle mitochondrial inner membrane, mitochondrial matrix, mitochondrial nucleoid, nucleolus, protein complex ATP binding, calcium ion binding, carbamoyl-phosphate synthase (ammonia) activity, endopeptidase activity, glutamate binding, metal ion binding, modified amino acid binding, phospholipid binding, protein binding, protein complex binding Human CPSF1 Reactome UniProtKB {GO:0006379=PMID:7590244, GO:0005515=PMID:21102410, GO:0008380=Reactome:REACT_1735, GO:0006378=PMID:7590244, GO:0006369=Reactome:REACT_894, GO:0010467=Reactome:REACT_71, GO:0006366=Reactome:REACT_1366, GO:0031124=Reactome:REACT_1849, GO:0006406=Reactome:REACT_1281, GO:0000398=Reactome:REACT_467, GO:0005847=PMID:21102410, GO:0005654=Reactome:REACT_1935, GO:0003730=PMID:7590244} Q10570 Cleavage and polyadenylation specificity factor subunit 1 protein 20130213 {GO:0006379=IDA, GO:0005515=IPI, GO:0008380=TAS, GO:0006378=IDA, GO:0006369=TAS, GO:0010467=TAS, GO:0006366=TAS, GO:0031124=TAS, GO:0006406=TAS, GO:0000398=TAS, GO:0005847=IDA, GO:0005654=TAS, GO:0003730=IDA} RNA splicing, gene expression, mRNA 3'-end processing, mRNA cleavage, mRNA export from nucleus, mRNA polyadenylation, mRNA splicing, via spliceosome, termination of RNA polymerase II transcription, transcription from RNA polymerase II promoter mRNA cleavage and polyadenylation specificity factor complex, nucleoplasm mRNA 3'-UTR binding, protein binding Human CPSF2 Reactome UniProtKB {GO:0006379=GO_REF:0000002, GO:0005515=PMID:18688255, GO:0008380=Reactome:REACT_1735, GO:0010467=Reactome:REACT_71, GO:0006378=GO_REF:0000002, GO:0006369=Reactome:REACT_894, GO:0006398=PMID:18688255, GO:0006366=Reactome:REACT_1366, GO:0003723=GO_REF:0000037, GO:0031124=Reactome:REACT_1849, GO:0006406=Reactome:REACT_1281, GO:0016787=GO_REF:0000002, GO:0000398=Reactome:REACT_467, GO:0005847=PMID:18305108, GO:0005654=Reactome:REACT_1935} Q9P2I0 Cleavage and polyadenylation specificity factor subunit 2 protein 20130213 {GO:0006379=IEA, GO:0005515=IPI, GO:0008380=TAS, GO:0010467=TAS, GO:0006378=IEA, GO:0006369=TAS, GO:0006398=IDA, GO:0006366=TAS, GO:0003723=IEA, GO:0031124=TAS, GO:0006406=TAS, GO:0016787=IEA, GO:0000398=TAS, GO:0005847=IDA, GO:0005654=TAS} RNA splicing, gene expression, histone mRNA 3'-end processing, mRNA 3'-end processing, mRNA cleavage, mRNA export from nucleus, mRNA polyadenylation, mRNA splicing, via spliceosome, termination of RNA polymerase II transcription, transcription from RNA polymerase II promoter mRNA cleavage and polyadenylation specificity factor complex, nucleoplasm RNA binding, hydrolase activity, protein binding Human CPSF3 Reactome UniProtKB {GO:0008380=Reactome:REACT_1735, GO:0005515=PMID:18688255, GO:0006379=PMID:8929409, GO:0010467=Reactome:REACT_71, GO:0006369=Reactome:REACT_894, GO:0006378=PMID:8929409, GO:0008409=GO_REF:0000024, GO:0006398=PMID:18688255, GO:0006366=Reactome:REACT_1366, GO:0003723=GO_REF:0000024, GO:0031124=Reactome:REACT_1849, GO:0004521=GO_REF:0000024, GO:0046872=GO_REF:0000037, GO:0006406=Reactome:REACT_1281, GO:0000398=Reactome:REACT_467, GO:0030529=GO_REF:0000037, GO:0005847=PMID:18305108, GO:0005654=Reactome:REACT_1935} Q9UKF6 Cleavage and polyadenylation specificity factor subunit 3 protein 20130213 {GO:0008380=TAS, GO:0005515=IPI, GO:0006379=TAS, GO:0010467=TAS, GO:0006369=TAS, GO:0006378=TAS, GO:0008409=ISS, GO:0006398=IDA, GO:0006366=TAS, GO:0003723=ISS, GO:0031124=TAS, GO:0004521=ISS, GO:0046872=IEA, GO:0006406=TAS, GO:0000398=TAS, GO:0030529=IEA, GO:0005847=IDA, GO:0005654=TAS} RNA splicing, gene expression, histone mRNA 3'-end processing, mRNA 3'-end processing, mRNA cleavage, mRNA export from nucleus, mRNA polyadenylation, mRNA splicing, via spliceosome, termination of RNA polymerase II transcription, transcription from RNA polymerase II promoter mRNA cleavage and polyadenylation specificity factor complex, nucleoplasm, ribonucleoprotein complex 5'-3' exonuclease activity, RNA binding, endoribonuclease activity, metal ion binding, protein binding Human CPSF3L UniProtKB UniProtKB {GO:0005737=GO_REF:0000039, GO:0016787=GO_REF:0000037, GO:0005634=GO_REF:0000039} Q5TA45 Integrator complex subunit 11 protein 20130413 {GO:0005737=IEA, GO:0016787=IEA, GO:0005634=IEA} cytoplasm, nucleus hydrolase activity Human UniProtKB-SubCell:SL-0086 CPSF4 HPA UniProtKB {GO:0006397=GO_REF:0000037, GO:0019054=Reactome:REACT_6222, GO:0003723=GO_REF:0000037, GO:0005730=GO_REF:0000052, GO:0019058=Reactome:REACT_6167, GO:0005634=GO_REF:0000052, GO:0003676=GO_REF:0000002, GO:0005739=GO_REF:0000052, GO:0046778=Reactome:REACT_6173, GO:0019048=Reactome:REACT_6323, GO:0005847=PMID:21102410, GO:0008270=GO_REF:0000002, GO:0005654=Reactome:REACT_6168} O95639 Cleavage and polyadenylation specificity factor subunit 4 protein 20120912 {GO:0006397=IEA, GO:0019054=TAS, GO:0003723=IEA, GO:0005730=IDA, GO:0019058=TAS, GO:0005634=IDA, GO:0003676=IEA, GO:0005739=IDA, GO:0046778=TAS, GO:0019048=TAS, GO:0005847=IDA, GO:0008270=IEA, GO:0005654=TAS} mRNA processing, modification by virus of host mRNA processing, modulation by virus of host cellular process, viral infectious cycle, virus-host interaction mRNA cleavage and polyadenylation specificity factor complex, mitochondrion, nucleolus, nucleoplasm, nucleus RNA binding, nucleic acid binding, zinc ion binding Human CPSF6 HPA UniProtKB {GO:0006397=PMID:14690600, GO:0005515=PMID:19447967, GO:0006378=PMID:20695905, GO:0051262=PMID:20695905, GO:0003723=PMID:15169763, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0003676=GO_REF:0000002, GO:0003729=PMID:21295486, GO:0042382=PMID:9659921, GO:0000166=GO_REF:0000002, GO:0030529=PMID:18809582, GO:0005849=PMID:20695905} Q16630 Cleavage and polyadenylation specificity factor subunit 6 protein 20110516 {GO:0006397=IDA, GO:0005515=IPI, GO:0006378=IMP, GO:0051262=IDA, GO:0003723=IDA, GO:0005730=IDA, GO:0005634=IDA, GO:0003676=IEA, GO:0003729=IDA, GO:0042382=IDA, GO:0000166=IEA, GO:0030529=IDA, GO:0005849=IDA} mRNA polyadenylation, mRNA processing, protein tetramerization mRNA cleavage factor complex, nucleolus, nucleus, paraspeckles, ribonucleoprotein complex RNA binding, mRNA binding, nucleic acid binding, nucleotide binding, protein binding NOT Human CPSF7 IntAct UniProtKB {GO:0005515=PMID:16713569, GO:0008380=Reactome:REACT_1735, GO:0006369=Reactome:REACT_894, GO:0010467=Reactome:REACT_71, GO:0051262=PMID:20695905, GO:0006366=Reactome:REACT_1366, GO:0003723=GO_REF:0000037, GO:0031124=Reactome:REACT_1849, GO:0005634=PMID:20695905, GO:0003676=GO_REF:0000002, GO:0000166=GO_REF:0000002, GO:0000398=Reactome:REACT_467, GO:0005849=PMID:20695905, GO:0005654=Reactome:REACT_1935} Q8N684 Cleavage and polyadenylation specificity factor subunit 7 protein 20130415 {GO:0005515=IPI, GO:0008380=TAS, GO:0006369=TAS, GO:0010467=TAS, GO:0051262=IDA, GO:0006366=TAS, GO:0003723=IEA, GO:0031124=TAS, GO:0005634=IDA, GO:0003676=IEA, GO:0000166=IEA, GO:0000398=TAS, GO:0005849=IDA, GO:0005654=TAS} RNA splicing, gene expression, mRNA 3'-end processing, mRNA splicing, via spliceosome, protein tetramerization, termination of RNA polymerase II transcription, transcription from RNA polymerase II promoter mRNA cleavage factor complex, nucleoplasm, nucleus RNA binding, nucleic acid binding, nucleotide binding, protein binding Human UniProtKB:P54253 CPT1A HPA UniProtKB {GO:0014070=GO_REF:0000019, GO:0001676=PMID:11350182, GO:0006635=GO_REF:0000041, GO:0016746=GO_REF:0000002, GO:0004095=PMID:11350182, GO:0006853=Reactome:REACT_11082, GO:0042493=GO_REF:0000019, GO:0005743=GO_REF:0000019, GO:0005741=Reactome:REACT_115644, GO:0044281=Reactome:REACT_111217, GO:0042802=GO_REF:0000019, GO:0005739=GO_REF:0000052, GO:0050796=GO_REF:0000019, GO:0032000=GO_REF:0000019, GO:0006006=GO_REF:0000019, GO:0006641=GO_REF:0000019, GO:0051260=GO_REF:0000019, GO:0042755=GO_REF:0000019, GO:0031307=GO_REF:0000024, GO:0009437=PMID:11350182, GO:0044255=Reactome:REACT_22279} P50416 Carnitine O-palmitoyltransferase 1, liver isoform protein 20080205 {GO:0014070=IEA, GO:0001676=IDA, GO:0006635=IEA, GO:0016746=IEA, GO:0004095=IDA, GO:0006853=TAS, GO:0042493=IEA, GO:0005743=IEA, GO:0005741=TAS, GO:0044281=TAS, GO:0042802=IEA, GO:0005739=IDA, GO:0050796=IEA, GO:0032000=IEA, GO:0006006=IEA, GO:0006641=IEA, GO:0051260=IEA, GO:0042755=IEA, GO:0031307=ISS, GO:0009437=IDA, GO:0044255=TAS} carnitine metabolic process, carnitine shuttle, cellular lipid metabolic process, eating behavior, fatty acid beta-oxidation, glucose metabolic process, long-chain fatty acid metabolic process, positive regulation of fatty acid beta-oxidation, protein homooligomerization, regulation of insulin secretion, response to drug, response to organic cyclic compound, small molecule metabolic process, triglyceride metabolic process integral to mitochondrial outer membrane, mitochondrial inner membrane, mitochondrial outer membrane, mitochondrion carnitine O-palmitoyltransferase activity, identical protein binding, transferase activity, transferring acyl groups Human CPT1B Reactome UniProtKB {GO:0005739=PMID:10408760, GO:0006635=GO_REF:0000041, GO:0016746=GO_REF:0000038, GO:0004095=GO_REF:0000003, GO:0006853=Reactome:REACT_11082, GO:0005741=Reactome:REACT_11185, GO:0044281=Reactome:REACT_111217, GO:0016021=GO_REF:0000037, GO:0015909=GO_REF:0000019, GO:0044255=Reactome:REACT_22279} Q92523 Carnitine O-palmitoyltransferase 1, muscle isoform protein 20130301 {GO:0005739=TAS, GO:0006635=IEA, GO:0016746=IEA, GO:0004095=IEA, GO:0006853=TAS, GO:0005741=TAS, GO:0044281=TAS, GO:0016021=IEA, GO:0015909=IEA, GO:0044255=TAS} carnitine shuttle, cellular lipid metabolic process, fatty acid beta-oxidation, long-chain fatty acid transport, small molecule metabolic process integral to membrane, mitochondrial outer membrane, mitochondrion carnitine O-palmitoyltransferase activity, transferase activity, transferring acyl groups Human CPT2 HPA UniProtKB {GO:0005739=GO_REF:0000052, GO:0006635=GO_REF:0000029, GO:0004095=PMID:1988962, GO:0006853=Reactome:REACT_11082, GO:0005730=GO_REF:0000052, GO:0005743=Reactome:REACT_115927, GO:0005634=GO_REF:0000052, GO:0044281=Reactome:REACT_111217, GO:0044255=Reactome:REACT_22279} P23786 Carnitine O-palmitoyltransferase 2, mitochondrial protein 20111111 {GO:0005739=IDA, GO:0006635=NAS, GO:0004095=NAS, GO:0006853=TAS, GO:0005730=IDA, GO:0005743=TAS, GO:0005634=IDA, GO:0044281=TAS, GO:0044255=TAS} carnitine shuttle, cellular lipid metabolic process, fatty acid beta-oxidation, small molecule metabolic process mitochondrial inner membrane, mitochondrion, nucleolus, nucleus carnitine O-palmitoyltransferase activity Human CPVL UniProtKB UniProtKB {GO:0004185=GO_REF:0000002, GO:0006508=GO_REF:0000037} Q9H3G5 Probable serine carboxypeptidase CPVL protein 20130413 {GO:0004185=IEA, GO:0006508=IEA} proteolysis serine-type carboxypeptidase activity Human UniProtKB-KW:KW-0645 CPXCR1 InterPro UniProtKB {GO:0008270=GO_REF:0000002} Q8N123 CPX chromosomal region candidate gene 1 protein protein 20130413 {GO:0008270=IEA} zinc ion binding Human InterPro:IPR007087 CPXM1 ENSEMBL UniProtKB {GO:0006508=GO_REF:0000037, GO:0008270=GO_REF:0000002, GO:0007155=GO_REF:0000002, GO:0005615=GO_REF:0000019, GO:0004181=GO_REF:0000002} Q96SM3 Probable carboxypeptidase X1 protein 20130413 {GO:0006508=IEA, GO:0008270=IEA, GO:0007155=IEA, GO:0005615=IEA, GO:0004181=IEA} cell adhesion, proteolysis extracellular space metallocarboxypeptidase activity, zinc ion binding Human Ensembl:ENSMUSP00000028897 CPXM2 InterPro UniProtKB {GO:0006508=GO_REF:0000002, GO:0008270=GO_REF:0000002, GO:0007155=GO_REF:0000002, GO:0004181=GO_REF:0000002} Q8N436 Inactive carboxypeptidase-like protein X2 protein 20130413 {GO:0006508=IEA, GO:0008270=IEA, GO:0007155=IEA, GO:0004181=IEA} cell adhesion, proteolysis metallocarboxypeptidase activity, zinc ion binding Human InterPro:IPR000834 CR1 Reactome UniProtKB {GO:0030449=Reactome:REACT_118707, GO:0009986=PMID:2972794, GO:0005886=Reactome:REACT_118692, GO:0001861=PMID:2972794, GO:0001855=PMID:2972794, GO:0001851=PMID:2972794, GO:0005887=PMID:6910481, GO:0045087=Reactome:REACT_6802, GO:0006958=GO_REF:0000037, GO:1900005=PMID:2972794, GO:0045959=PMID:10531307, GO:1900004=PMID:6910481, GO:0045957=PMID:10531307, GO:0004877=PMID:2972794} P17927 Complement receptor type 1 protein 20130213 {GO:0030449=TAS, GO:0009986=IDA, GO:0005886=TAS, GO:0001861=IDA, GO:0001855=IDA, GO:0001851=IDA, GO:0005887=IDA, GO:0045087=TAS, GO:0006958=IEA, GO:1900005=IDA, GO:0045959=IDA, GO:1900004=IDA, GO:0045957=IDA, GO:0004877=IDA} complement activation, classical pathway, innate immune response, negative regulation of complement activation, alternative pathway, negative regulation of complement activation, classical pathway, negative regulation of serine-type endopeptidase activity, positive regulation of serine-type endopeptidase activity, regulation of complement activation cell surface, integral to plasma membrane, plasma membrane complement component C3b binding, complement component C3b receptor activity, complement component C4b binding, complement component C4b receptor activity Human CR2 MGI UniProtKB {GO:0042113=GO_REF:0000019, GO:0006955=PMID:2827171, GO:0005886=PMID:2563370, GO:0045087=GO_REF:0000037, GO:0006958=GO_REF:0000037, GO:0016021=PMID:2827171, GO:0042803=PMID:11728339, GO:0009897=GO_REF:0000019, GO:0004888=PMID:2827171, GO:0004875=PMID:2827171} P20023 Complement receptor type 2 protein 20110203 {GO:0042113=IEA, GO:0006955=NAS, GO:0005886=NAS, GO:0045087=IEA, GO:0006958=IEA, GO:0016021=NAS, GO:0042803=IDA, GO:0009897=IEA, GO:0004888=NAS, GO:0004875=NAS} B cell activation, complement activation, classical pathway, immune response, innate immune response external side of plasma membrane, integral to membrane, plasma membrane complement receptor activity, protein homodimerization activity, transmembrane signaling receptor activity Human CRABP1 PINC UniProtKB {GO:0007165=PMID:1309505, GO:0005215=GO_REF:0000002, GO:0001972=GO_REF:0000019, GO:0005501=PMID:1309505, GO:0016918=GO_REF:0000037, GO:0007275=PMID:1309505, GO:0019841=GO_REF:0000037, GO:0005829=GO_REF:0000019} P29762 Cellular retinoic acid-binding protein 1 protein 20030904 {GO:0007165=TAS, GO:0005215=IEA, GO:0001972=IEA, GO:0005501=TAS, GO:0016918=IEA, GO:0007275=TAS, GO:0019841=IEA, GO:0005829=IEA} multicellular organismal development, signal transduction cytosol retinal binding, retinoic acid binding, retinoid binding, retinol binding, transporter activity Human CRABP2 ENSEMBL UniProtKB {GO:0005215=GO_REF:0000002, GO:0006355=PMID:1334086, GO:0005783=GO_REF:0000039, GO:0016918=GO_REF:0000037, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0019841=GO_REF:0000037, GO:0007165=PMID:1654334, GO:0005737=GO_REF:0000019, GO:0008544=PMID:1654334, GO:0042573=GO_REF:0000019, GO:0001972=GO_REF:0000019, GO:0005501=PMID:1334086, GO:0035115=GO_REF:0000019} Q5SYZ4 Cellular retinoic acid-binding protein 2 protein 20130413 {GO:0005215=IEA, GO:0006355=TAS, GO:0005783=IEA, GO:0016918=IEA, GO:0005730=IDA, GO:0005634=IDA, GO:0019841=IEA, GO:0007165=TAS, GO:0005737=IEA, GO:0008544=TAS, GO:0042573=IEA, GO:0001972=IEA, GO:0005501=TAS, GO:0035115=IEA} embryonic forelimb morphogenesis, epidermis development, regulation of transcription, DNA-dependent, retinoic acid metabolic process, signal transduction cytoplasm, endoplasmic reticulum, nucleolus, nucleus retinal binding, retinoic acid binding, retinoid binding, retinol binding, transporter activity Human Ensembl:ENSMUSP00000005019 CRADD BHF-UCL UniProtKB {GO:0005515=PMID:16652156, GO:0008625=PMID:9044836, GO:0005622=GO_REF:0000002, GO:0070513=PMID:9044836, GO:0005737=GO_REF:0000024, GO:0005634=GO_REF:0000024, GO:0042981=GO_REF:0000002, GO:0006917=PMID:9044836, GO:0030674=PMID:9044836, GO:0002020=PMID:9044836, GO:0071260=PMID:19593445} P78560 Death domain-containing protein CRADD protein 20090323 {GO:0005515=IPI, GO:0008625=TAS, GO:0005622=IEA, GO:0070513=IPI, GO:0005737=ISS, GO:0005634=ISS, GO:0042981=IEA, GO:0006917=IDA, GO:0030674=IPI, GO:0002020=IPI, GO:0071260=IEP} cellular response to mechanical stimulus, extrinsic apoptotic signaling pathway via death domain receptors, induction of apoptosis, regulation of apoptotic process cytoplasm, intracellular, nucleus death domain binding, protease binding, protein binding, protein binding, bridging Human UniProtKB:P42575 CRAMP1L UniProtKB UniProtKB {GO:0003682=GO_REF:0000002, GO:0005634=GO_REF:0000039, GO:0003677=GO_REF:0000037} Q96RY5 Protein cramped-like protein 20130413 {GO:0003682=IEA, GO:0005634=IEA, GO:0003677=IEA} nucleus DNA binding, chromatin binding Human UniProtKB-SubCell:SL-0191 CRAT Reactome UniProtKB {GO:0004092=PMID:15099582, GO:0016746=GO_REF:0000002, GO:0005782=Reactome:REACT_16977, GO:0005783=GO_REF:0000039, GO:0005743=GO_REF:0000039, GO:0005102=PMID:20178365, GO:0044281=Reactome:REACT_111217, GO:0019254=PMID:2351134, GO:0005739=PMID:2351134, GO:0006810=GO_REF:0000037, GO:0033540=Reactome:REACT_17062, GO:0044255=Reactome:REACT_16957, GO:0005777=PMID:2351134} P43155 Carnitine O-acetyltransferase protein 20130301 {GO:0004092=IDA, GO:0016746=IEA, GO:0005782=TAS, GO:0005783=IEA, GO:0005743=IEA, GO:0005102=IPI, GO:0044281=TAS, GO:0019254=IDA, GO:0005739=IDA, GO:0006810=IEA, GO:0033540=TAS, GO:0044255=TAS, GO:0005777=IDA} carnitine metabolic process, CoA-linked, cellular lipid metabolic process, fatty acid beta-oxidation using acyl-CoA oxidase, small molecule metabolic process, transport endoplasmic reticulum, mitochondrial inner membrane, mitochondrion, peroxisomal matrix, peroxisome carnitine O-acetyltransferase activity, receptor binding, transferase activity, transferring acyl groups Human CRB1 PINC UniProtKB {GO:0007009=GO_REF:0000019, GO:0005902=GO_REF:0000019, GO:0016324=GO_REF:0000039, GO:0007163=PMID:10508521, GO:0005886=GO_REF:0000019, GO:0005509=GO_REF:0000002, GO:0007267=PMID:10508521, GO:0005576=GO_REF:0000039, GO:0016021=GO_REF:0000037, GO:0042462=GO_REF:0000019} P82279 Protein crumbs homolog 1 protein 20030904 {GO:0007009=IEA, GO:0005902=IEA, GO:0016324=IEA, GO:0007163=TAS, GO:0005886=IEA, GO:0005509=IEA, GO:0007267=TAS, GO:0005576=IEA, GO:0016021=IEA, GO:0042462=IEA} cell-cell signaling, establishment or maintenance of cell polarity, eye photoreceptor cell development, plasma membrane organization apical plasma membrane, extracellular region, integral to membrane, microvillus, plasma membrane calcium ion binding Human CRB2 UniProtKB UniProtKB {GO:0005886=GO_REF:0000039, GO:0005509=GO_REF:0000002, GO:0005576=GO_REF:0000039, GO:0016021=GO_REF:0000037} Q5IJ48 Protein crumbs homolog 2 protein 20130413 {GO:0005886=IEA, GO:0005509=IEA, GO:0005576=IEA, GO:0016021=IEA} extracellular region, integral to membrane, plasma membrane calcium ion binding Human UniProtKB-SubCell:SL-0039 CRB3 BHF-UCL UniProtKB {GO:0017124=PMID:17332497, GO:0016324=GO_REF:0000039, GO:0070830=Reactome:REACT_19373, GO:0005886=Reactome:REACT_19144, GO:0034329=Reactome:REACT_20676, GO:0019904=PMID:17332497, GO:0005923=GO_REF:0000039, GO:0016021=GO_REF:0000037, GO:0072659=PMID:17332497, GO:0045216=Reactome:REACT_19331} Q9BUF7 Protein crumbs homolog 3 protein 20110307 {GO:0017124=IPI, GO:0016324=IEA, GO:0070830=TAS, GO:0005886=TAS, GO:0034329=TAS, GO:0019904=IPI, GO:0005923=IEA, GO:0016021=IEA, GO:0072659=IDA, GO:0045216=TAS} cell junction assembly, cell-cell junction organization, protein localization to plasma membrane, tight junction assembly apical plasma membrane, integral to membrane, plasma membrane, tight junction SH3 domain binding, protein domain specific binding Human UniProtKB:Q5T2T1 CRBN HPA UniProtKB {GO:0005515=PMID:20223979, GO:0032463=GO_REF:0000019, GO:0090073=GO_REF:0000019, GO:0016567=PMID:20223979, GO:0005730=GO_REF:0000052, GO:0005634=PMID:20223979, GO:0005737=PMID:20223979, GO:0016020=GO_REF:0000039, GO:0004176=GO_REF:0000002, GO:0006508=GO_REF:0000002, GO:0043161=PMID:20223979, GO:0031464=PMID:20223979, GO:0034766=GO_REF:0000019} Q96SW2 Protein cereblon protein 20111111 {GO:0005515=IPI, GO:0032463=IEA, GO:0090073=IEA, GO:0016567=IMP, GO:0005730=IDA, GO:0005634=IDA, GO:0005737=IDA, GO:0016020=IEA, GO:0004176=IEA, GO:0006508=IEA, GO:0043161=IMP, GO:0031464=IDA, GO:0034766=IEA} negative regulation of ion transmembrane transport, negative regulation of protein homooligomerization, positive regulation of protein homodimerization activity, proteasomal ubiquitin-dependent protein catabolic process, protein ubiquitination, proteolysis Cul4A-RING ubiquitin ligase complex, cytoplasm, membrane, nucleolus, nucleus ATP-dependent peptidase activity, protein binding Human CRCP UniProtKB UniProtKB {GO:0004948=PMID:8622957, GO:0009360=PMID:12482973, GO:0001669=GO_REF:0000019, GO:0005886=GO_REF:0000039, GO:0003899=PMID:12482973, GO:0005634=GO_REF:0000039, GO:0006383=PMID:12482973, GO:0006351=GO_REF:0000002, GO:0051607=GO_REF:0000037, GO:0000166=GO_REF:0000002, GO:0007218=GO_REF:0000019, GO:0045087=GO_REF:0000037, GO:0007340=PMID:10067875, GO:0001635=GO_REF:0000019} O75575 DNA-directed RNA polymerase III subunit RPC9 protein 20080312 {GO:0004948=NAS, GO:0009360=IDA, GO:0001669=IEA, GO:0005886=IEA, GO:0003899=IDA, GO:0005634=IEA, GO:0006383=IDA, GO:0006351=IEA, GO:0051607=IEA, GO:0000166=IEA, GO:0007218=IEA, GO:0045087=IEA, GO:0007340=NAS, GO:0001635=IEA} acrosome reaction, defense response to virus, innate immune response, neuropeptide signaling pathway, transcription from RNA polymerase III promoter, transcription, DNA-dependent DNA polymerase III complex, acrosomal vesicle, nucleus, plasma membrane DNA-directed RNA polymerase activity, calcitonin gene-related polypeptide receptor activity, calcitonin receptor activity, nucleotide binding Human CRCT1 null null {} null null null null {} null null null CREB1 BHF-UCL UniProtKB {GO:0005515=PMID:21988832, GO:0008361=GO_REF:0000019, GO:0000790=GO_REF:0000019, GO:0001190=PMID:19861239, GO:0003700=PMID:8798441, GO:0003705=PMID:19861239, GO:0007409=GO_REF:0000019, GO:0051403=Reactome:REACT_21308, GO:0046889=GO_REF:0000024, GO:0002756=Reactome:REACT_6809, GO:0010944=PMID:19861239, GO:0007173=Reactome:REACT_9417, GO:0007411=Reactome:REACT_18266, GO:0002755=Reactome:REACT_27215, GO:0046887=GO_REF:0000019, GO:0003712=PMID:8552098, GO:0001102=PMID:19861239, GO:0038124=Reactome:REACT_8006, GO:0038123=Reactome:REACT_8005, GO:0005719=PMID:19861239, GO:0034134=Reactome:REACT_7980, GO:0002224=Reactome:REACT_9020, GO:0008543=Reactome:REACT_9470, GO:0045087=Reactome:REACT_6802, GO:0045600=GO_REF:0000024, GO:0000980=PMID:19861239, GO:0005654=Reactome:REACT_147870, GO:0034166=Reactome:REACT_9027, GO:0035666=Reactome:REACT_25281, GO:0045893=GO_REF:0000024, GO:0034162=Reactome:REACT_9047, GO:0034142=Reactome:REACT_6894, GO:0035497=PMID:19861239, GO:0021983=GO_REF:0000019, GO:0007268=Reactome:REACT_13685, GO:0005634=GO_REF:0000052, GO:0007202=Reactome:REACT_12079, GO:0045944=PMID:19861239, GO:0040018=GO_REF:0000019, GO:0034138=Reactome:REACT_6783, GO:0005667=GO_REF:0000019, GO:0048011=Reactome:REACT_11061, GO:0010033=PMID:8798441, GO:0042493=GO_REF:0000019, GO:0048015=Reactome:REACT_12464, GO:0005730=GO_REF:0000052, GO:0050821=GO_REF:0000024, GO:0003677=GO_REF:0000002, GO:0043565=GO_REF:0000019, GO:0007165=Reactome:REACT_12478, GO:0071363=GO_REF:0000019, GO:0007595=GO_REF:0000019, GO:0019048=GO_REF:0000037, GO:0006468=PMID:8798441, GO:0034146=Reactome:REACT_9061} P16220 Cyclic AMP-responsive element-binding protein 1 protein 20111201 {GO:0005515=IPI, GO:0008361=IEA, GO:0000790=IEA, GO:0001190=IDA, GO:0003700=IDA, GO:0003705=IDA, GO:0007409=IEA, GO:0051403=TAS, GO:0046889=ISS, GO:0002756=TAS, GO:0010944=IDA, GO:0007173=TAS, GO:0007411=TAS, GO:0002755=TAS, GO:0046887=IEA, GO:0003712=TAS, GO:0001102=IPI, GO:0038124=TAS, GO:0038123=TAS, GO:0005719=IDA, GO:0034134=TAS, GO:0002224=TAS, GO:0008543=TAS, GO:0045087=TAS, GO:0045600=ISS, GO:0000980=IDA, GO:0005654=TAS, GO:0034166=TAS, GO:0035666=TAS, GO:0045893=ISS, GO:0034162=TAS, GO:0034142=TAS, GO:0035497=IDA, GO:0021983=IEA, GO:0007268=TAS, GO:0005634=IDA, GO:0007202=TAS, GO:0045944=IDA, GO:0040018=IEA, GO:0034138=TAS, GO:0005667=IEA, GO:0048011=TAS, GO:0010033=IDA, GO:0042493=IEA, GO:0048015=TAS, GO:0005730=IDA, GO:0050821=ISS, GO:0003677=IEA, GO:0043565=IEA, GO:0007165=TAS, GO:0071363=IEA, GO:0007595=IEA, GO:0019048=IEA, GO:0006468=IDA, GO:0034146=TAS} MyD88-dependent toll-like receptor signaling pathway, MyD88-independent toll-like receptor signaling pathway, TRIF-dependent toll-like receptor signaling pathway, activation of phospholipase C activity, axon guidance, axonogenesis, cellular response to growth factor stimulus, epidermal growth factor receptor signaling pathway, fibroblast growth factor receptor signaling pathway, innate immune response, lactation, negative regulation of transcription by competitive promoter binding, neurotrophin TRK receptor signaling pathway, phosphatidylinositol-mediated signaling, pituitary gland development, positive regulation of fat cell differentiation, positive regulation of hormone secretion, positive regulation of lipid biosynthetic process, positive regulation of multicellular organism growth, positive regulation of transcription from RNA polymerase II promoter, positive regulation of transcription, DNA-dependent, protein phosphorylation, protein stabilization, regulation of cell size, response to drug, response to organic substance, signal transduction, stress-activated MAPK cascade, synaptic transmission, toll-like receptor 10 signaling pathway, toll-like receptor 2 signaling pathway, toll-like receptor 3 signaling pathway, toll-like receptor 4 signaling pathway, toll-like receptor 5 signaling pathway, toll-like receptor 9 signaling pathway, toll-like receptor TLR1:TLR2 signaling pathway, toll-like receptor TLR6:TLR2 signaling pathway, toll-like receptor signaling pathway, virus-host interaction nuclear chromatin, nuclear euchromatin, nucleolus, nucleoplasm, nucleus, transcription factor complex DNA binding, RNA polymerase II activating transcription factor binding, RNA polymerase II distal enhancer sequence-specific DNA binding, RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity, RNA polymerase II transcription factor binding transcription factor activity involved in positive regulation of transcription, cAMP response element binding, protein binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, transcription cofactor activity Human CREB3 IntAct UniProtKB {GO:0005515=PMID:20195357, GO:0043565=GO_REF:0000019, GO:0006986=GO_REF:0000037, GO:0003700=GO_REF:0000002, GO:0006935=GO_REF:0000037, GO:0045944=PMID:98051186, GO:0019048=GO_REF:0000037, GO:0005789=GO_REF:0000039, GO:0005634=PMID:20546900, GO:0090026=PMID:17296613, GO:0016021=GO_REF:0000037, GO:0006351=GO_REF:0000037} O43889 Cyclic AMP-responsive element-binding protein 3 protein 20130415 {GO:0005515=IPI, GO:0043565=IEA, GO:0006986=IEA, GO:0003700=IEA, GO:0006935=IEA, GO:0045944=IDA, GO:0019048=IEA, GO:0005789=IEA, GO:0005634=IDA, GO:0090026=IDA, GO:0016021=IEA, GO:0006351=IEA} chemotaxis, positive regulation of monocyte chemotaxis, positive regulation of transcription from RNA polymerase II promoter, response to unfolded protein, transcription, DNA-dependent, virus-host interaction endoplasmic reticulum membrane, integral to membrane, nucleus protein binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity Human UniProtKB:P05412 CREB3L1 UniProtKB UniProtKB {GO:0006986=GO_REF:0000037, GO:0043565=GO_REF:0000002, GO:0030500=GO_REF:0000019, GO:0001077=GO_REF:0000019, GO:0003700=GO_REF:0000002, GO:0005783=GO_REF:0000019, GO:0003682=GO_REF:0000019, GO:0005789=GO_REF:0000039, GO:0005634=GO_REF:0000039, GO:0016021=GO_REF:0000037} Q96BA8 Cyclic AMP-responsive element-binding protein 3-like protein 1 protein 20130413 {GO:0006986=IEA, GO:0043565=IEA, GO:0030500=IEA, GO:0001077=IEA, GO:0003700=IEA, GO:0005783=IEA, GO:0003682=IEA, GO:0005789=IEA, GO:0005634=IEA, GO:0016021=IEA} regulation of bone mineralization, response to unfolded protein endoplasmic reticulum, endoplasmic reticulum membrane, integral to membrane, nucleus RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription, chromatin binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity Human UniProtKB-SubCell:SL-0097 CREB3L2 UniProtKB UniProtKB {GO:0006986=GO_REF:0000037, GO:0034976=PMID:17178827, GO:0003700=GO_REF:0000002, GO:0044212=PMID:17178827, GO:0051216=GO_REF:0000024, GO:0035497=PMID:17178827, GO:0005783=PMID:17178827, GO:0005634=PMID:17178827, GO:0006351=GO_REF:0000037, GO:0043565=GO_REF:0000002, GO:0006888=GO_REF:0000019, GO:0002062=GO_REF:0000024, GO:0005789=GO_REF:0000039, GO:0016021=GO_REF:0000037, GO:0045893=PMID:17178827} Q70SY1 Cyclic AMP-responsive element-binding protein 3-like protein 2 protein 20100504 {GO:0006986=IEA, GO:0034976=IEP, GO:0003700=IEA, GO:0044212=IMP, GO:0051216=ISS, GO:0035497=IMP, GO:0005783=IDA, GO:0005634=IDA, GO:0006351=IEA, GO:0043565=IEA, GO:0006888=IEA, GO:0002062=ISS, GO:0005789=IEA, GO:0016021=IEA, GO:0045893=IDA} ER to Golgi vesicle-mediated transport, cartilage development, chondrocyte differentiation, positive regulation of transcription, DNA-dependent, response to endoplasmic reticulum stress, response to unfolded protein, transcription, DNA-dependent endoplasmic reticulum, endoplasmic reticulum membrane, integral to membrane, nucleus cAMP response element binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, transcription regulatory region DNA binding Human UniProtKB:Q8BH52 CREB3L3 InterPro UniProtKB {GO:0005515=PMID:16469704, GO:0006986=GO_REF:0000037, GO:0043565=GO_REF:0000002, GO:0005737=GO_REF:0000052, GO:0003700=GO_REF:0000002, GO:0005789=GO_REF:0000039, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0016021=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q9Y4A3 R33590_1 protein 20130413 {GO:0005515=IPI, GO:0006986=IEA, GO:0043565=IEA, GO:0005737=IDA, GO:0003700=IEA, GO:0005789=IEA, GO:0005730=IDA, GO:0005634=IDA, GO:0016021=IEA, GO:0006351=IEA} response to unfolded protein, transcription, DNA-dependent cytoplasm, endoplasmic reticulum membrane, integral to membrane, nucleolus, nucleus protein binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity Human InterPro:IPR004827 CREB3L4 UniProtKB UniProtKB {GO:0006986=GO_REF:0000037, GO:0043565=GO_REF:0000002, GO:0003700=GO_REF:0000002, GO:0000139=GO_REF:0000039, GO:0005783=GO_REF:0000019, GO:0045944=GO_REF:0000019, GO:0005789=GO_REF:0000039, GO:0005634=GO_REF:0000039, GO:0016021=GO_REF:0000037, GO:0007283=GO_REF:0000019, GO:0006351=GO_REF:0000037} Q8TEY5 Cyclic AMP-responsive element-binding protein 3-like protein 4 protein 20130413 {GO:0006986=IEA, GO:0043565=IEA, GO:0003700=IEA, GO:0000139=IEA, GO:0005783=IEA, GO:0045944=IEA, GO:0005789=IEA, GO:0005634=IEA, GO:0016021=IEA, GO:0007283=IEA, GO:0006351=IEA} positive regulation of transcription from RNA polymerase II promoter, response to unfolded protein, spermatogenesis, transcription, DNA-dependent Golgi membrane, endoplasmic reticulum, endoplasmic reticulum membrane, integral to membrane, nucleus sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity Human UniProtKB-SubCell:SL-0097 CREB5 PINC UniProtKB {GO:0005515=PMID:8440710, GO:0043565=GO_REF:0000002, GO:0001077=GO_REF:0000019, GO:0003700=PMID:8378084, GO:0006366=PMID:8378084, GO:0045444=GO_REF:0000019, GO:0008270=GO_REF:0000002, GO:0005634=PMID:8378084, GO:0045893=PMID:8378084, GO:0003676=GO_REF:0000002, GO:0060612=GO_REF:0000019} Q02930 Cyclic AMP-responsive element-binding protein 5 protein 20030904 {GO:0005515=IPI, GO:0043565=IEA, GO:0001077=IEA, GO:0003700=IDA, GO:0006366=TAS, GO:0045444=IEA, GO:0008270=IEA, GO:0005634=IC, GO:0045893=IDA, GO:0003676=IEA, GO:0060612=IEA} adipose tissue development, fat cell differentiation, positive regulation of transcription, DNA-dependent, transcription from RNA polymerase II promoter nucleus RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription, nucleic acid binding, protein binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, zinc ion binding Human CREBBP BHF-UCL UniProtKB {GO:0005515=PMID:16043483, GO:0001191=PMID:21539536, GO:0000987=PMID:21539536, GO:0010467=Reactome:REACT_71, GO:0000790=PMID:21539536, GO:0003700=PMID:7913207, GO:0006367=Reactome:REACT_14835, GO:0018076=PMID:12435739, GO:0007219=Reactome:REACT_118859, GO:0000123=GO_REF:0000019, GO:0044255=Reactome:REACT_22279, GO:0003712=GO_REF:0000002, GO:0001102=PMID:11001584, GO:0001105=PMID:11001584, GO:0003713=PMID:12169688, GO:0033554=Reactome:REACT_120956, GO:0000122=PMID:21539536, GO:0045087=Reactome:REACT_6802, GO:0016407=PMID:11742995, GO:0008270=GO_REF:0000002, GO:0005654=Reactome:REACT_160309, GO:0045893=PMID:11742995, GO:0042733=PMID:11001584, GO:0008134=PMID:15509593, GO:0061418=Reactome:REACT_120815, GO:0005634=PMID:12169688, GO:0044281=Reactome:REACT_111217, GO:0002039=PMID:9194565, GO:0005737=PMID:12929931, GO:0045944=GO_REF:0000019, GO:0001085=PMID:21539536, GO:0004871=PMID:8028671, GO:0030718=GO_REF:0000019, GO:0004402=PMID:11742995, GO:0001666=PMID:15261140, GO:0005667=GO_REF:0000019, GO:0006355=PMID:12169688, GO:0016573=PMID:11742995, GO:0043426=PMID:8621548, GO:0071456=Reactome:REACT_121311, GO:0042592=PMID:15261140, GO:0003677=GO_REF:0000019, GO:0007165=PMID:15261140, GO:0016604=PMID:15488321, GO:0001078=PMID:21539536, GO:0000940=GO_REF:0000019, GO:0006461=PMID:7913207, GO:0008589=PMID:11001584, GO:0019048=GO_REF:0000037, GO:0003682=GO_REF:0000019} Q92793 CREB-binding protein protein 20111118 {GO:0005515=IPI, GO:0001191=IDA, GO:0000987=IDA, GO:0010467=TAS, GO:0000790=IDA, GO:0003700=TAS, GO:0006367=TAS, GO:0018076=IDA, GO:0007219=TAS, GO:0000123=IEA, GO:0044255=TAS, GO:0003712=IEA, GO:0001102=TAS, GO:0001105=TAS, GO:0003713=IDA, GO:0033554=TAS, GO:0000122=IDA, GO:0045087=TAS, GO:0016407=IDA, GO:0008270=IEA, GO:0005654=TAS, GO:0045893=IDA, GO:0042733=TAS, GO:0008134=IPI, GO:0061418=TAS, GO:0005634=IC, GO:0044281=TAS, GO:0002039=IPI, GO:0005737=IDA, GO:0045944=IEA, GO:0001085=IPI, GO:0004871=TAS, GO:0030718=IEA, GO:0004402=IDA, GO:0001666=TAS, GO:0005667=IEA, GO:0006355=IDA, GO:0016573=IDA, GO:0043426=IDA, GO:0071456=TAS, GO:0042592=NAS, GO:0003677=IEA, GO:0007165=NAS, GO:0016604=IDA, GO:0001078=IDA, GO:0000940=IEA, GO:0006461=TAS, GO:0008589=TAS, GO:0019048=IEA, GO:0003682=IEA} N-terminal peptidyl-lysine acetylation, Notch signaling pathway, cellular lipid metabolic process, cellular response to hypoxia, cellular response to stress, embryonic digit morphogenesis, gene expression, germ-line stem cell maintenance, histone acetylation, homeostatic process, innate immune response, negative regulation of transcription from RNA polymerase II promoter, positive regulation of transcription from RNA polymerase II promoter, positive regulation of transcription, DNA-dependent, protein complex assembly, regulation of smoothened signaling pathway, regulation of transcription from RNA polymerase II promoter in response to hypoxia, regulation of transcription, DNA-dependent, response to hypoxia, signal transduction, small molecule metabolic process, transcription initiation from RNA polymerase II promoter, virus-host interaction condensed chromosome outer kinetochore, cytoplasm, histone acetyltransferase complex, nuclear body, nuclear chromatin, nucleoplasm, nucleus, transcription factor complex DNA binding, MRF binding, RNA polymerase II activating transcription factor binding, RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription, RNA polymerase II transcription coactivator activity, RNA polymerase II transcription factor binding, RNA polymerase II transcription factor binding transcription factor activity involved in negative regulation of transcription, acetyltransferase activity, chromatin binding, core promoter proximal region sequence-specific DNA binding, histone acetyltransferase activity, p53 binding, protein binding, sequence-specific DNA binding transcription factor activity, signal transducer activity, transcription coactivator activity, transcription cofactor activity, transcription factor binding, zinc ion binding Human CREBL2 UniProtKB UniProtKB {GO:0003700=GO_REF:0000002, GO:0050821=GO_REF:0000024, GO:0005634=GO_REF:0000024, GO:0006351=GO_REF:0000037, GO:0030154=GO_REF:0000037, GO:0043565=GO_REF:0000002, GO:0007165=PMID:9693048, GO:0046889=GO_REF:0000024, GO:0007049=GO_REF:0000037, GO:0033138=GO_REF:0000024, GO:0046326=GO_REF:0000024, GO:0045600=GO_REF:0000024, GO:0045893=GO_REF:0000024} O60519 cAMP-responsive element-binding protein-like 2 protein 20111216 {GO:0003700=IEA, GO:0050821=ISS, GO:0005634=ISS, GO:0006351=IEA, GO:0030154=IEA, GO:0043565=IEA, GO:0007165=TAS, GO:0046889=ISS, GO:0007049=IEA, GO:0033138=ISS, GO:0046326=ISS, GO:0045600=ISS, GO:0045893=ISS} cell cycle, cell differentiation, positive regulation of fat cell differentiation, positive regulation of glucose import, positive regulation of lipid biosynthetic process, positive regulation of peptidyl-serine phosphorylation, positive regulation of transcription, DNA-dependent, protein stabilization, signal transduction, transcription, DNA-dependent nucleus sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity Human UniProtKB:Q32M00 CREBZF IntAct UniProtKB {GO:0005515=PMID:19690166, GO:0043565=GO_REF:0000002, GO:0051090=PMID:15705566, GO:0003700=GO_REF:0000002, GO:0045814=PMID:15705566, GO:0005634=PMID:15705566, GO:0009615=PMID:10871379, GO:0003677=PMID:10871379, GO:0045892=PMID:15705566, GO:0006351=PMID:10871379} Q9NS37 CREB/ATF bZIP transcription factor protein 20130415 {GO:0005515=IPI, GO:0043565=IEA, GO:0051090=IDA, GO:0003700=IEA, GO:0045814=IEP, GO:0005634=IDA, GO:0009615=IDA, GO:0003677=NAS, GO:0045892=IMP, GO:0006351=IDA} negative regulation of gene expression, epigenetic, negative regulation of transcription, DNA-dependent, regulation of sequence-specific DNA binding transcription factor activity, response to virus, transcription, DNA-dependent nucleus DNA binding, protein binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity Human UniProtKB:Q96EB6 CREG1 PINC UniProtKB {GO:0005667=GO_REF:0000019, GO:0006357=PMID:9710587, GO:0008283=PMID:9710587, GO:0003714=PMID:9710587, GO:0010181=GO_REF:0000002, GO:0016491=GO_REF:0000002, GO:0007275=PMID:9710587, GO:0005576=GO_REF:0000039, GO:0040008=GO_REF:0000037, GO:0008134=GO_REF:0000019} O75629 Protein CREG1 protein 20030904 {GO:0005667=IEA, GO:0006357=TAS, GO:0008283=TAS, GO:0003714=TAS, GO:0010181=IEA, GO:0016491=IEA, GO:0007275=TAS, GO:0005576=IEA, GO:0040008=IEA, GO:0008134=IEA} cell proliferation, multicellular organismal development, regulation of growth, regulation of transcription from RNA polymerase II promoter extracellular region, transcription factor complex FMN binding, oxidoreductase activity, transcription corepressor activity, transcription factor binding Human CRELD1 BHF-UCL UniProtKB {GO:0003279=PMID:18076106, GO:0003197=PMID:18076106, GO:0005509=GO_REF:0000002, GO:0016021=GO_REF:0000037} Q96HD1 Cysteine-rich with EGF-like domain protein 1 protein 20100520 {GO:0003279=TAS, GO:0003197=TAS, GO:0005509=IEA, GO:0016021=IEA} cardiac septum development, endocardial cushion development integral to membrane calcium ion binding Human CRELD2 IntAct UniProtKB {GO:0005515=PMID:21988832, GO:0005794=GO_REF:0000019, GO:0005783=GO_REF:0000039, GO:0005509=GO_REF:0000002, GO:0005615=GO_REF:0000019} Q6UXH1 Cysteine-rich with EGF-like domain protein 2 protein 20130415 {GO:0005515=IPI, GO:0005794=IEA, GO:0005783=IEA, GO:0005509=IEA, GO:0005615=IEA} Golgi apparatus, endoplasmic reticulum, extracellular space calcium ion binding, protein binding Human UniProtKB:P42771 CREM InterPro UniProtKB {GO:0005667=GO_REF:0000019, GO:0006355=PMID:8206879, GO:0003700=GO_REF:0000002, GO:0006687=GO_REF:0000019, GO:0005634=GO_REF:0000002, GO:0007275=GO_REF:0000037, GO:0007283=GO_REF:0000037, GO:0003677=PMID:7916662, GO:0006351=GO_REF:0000037, GO:0030154=GO_REF:0000037, GO:0043565=GO_REF:0000002, GO:0007165=PMID:7916662, GO:0008140=PMID:8206879, GO:0045944=GO_REF:0000019} Q5W1A7 cAMP responsive element modulator, isoform CRA_b protein 20130413 {GO:0005667=IEA, GO:0006355=IDA, GO:0003700=IEA, GO:0006687=IEA, GO:0005634=IEA, GO:0007275=IEA, GO:0007283=IEA, GO:0003677=NAS, GO:0006351=IEA, GO:0030154=IEA, GO:0043565=IEA, GO:0007165=TAS, GO:0008140=NAS, GO:0045944=IEA} cell differentiation, glycosphingolipid metabolic process, multicellular organismal development, positive regulation of transcription from RNA polymerase II promoter, regulation of transcription, DNA-dependent, signal transduction, spermatogenesis, transcription, DNA-dependent nucleus, transcription factor complex DNA binding, cAMP response element binding protein binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity Human InterPro:IPR004827 CRH BHF-UCL UniProtKB {GO:0005515=PMID:18801728, GO:0043627=GO_REF:0000019, GO:0032811=GO_REF:0000019, GO:0033685=GO_REF:0000019, GO:0006704=GO_REF:0000019, GO:2000310=PMID:12895416, GO:2000854=GO_REF:0000019, GO:0005615=PMID:18559919, GO:0007611=PMID:7477348, GO:0060548=GO_REF:0000019, GO:0005184=PMID:7867564, GO:0010942=GO_REF:0000019, GO:0035641=GO_REF:0000019, GO:0008306=GO_REF:0000019, GO:0014062=GO_REF:0000019, GO:0051412=GO_REF:0000019, GO:0007565=PMID:18559919, GO:0007567=PMID:7585095, GO:0007616=GO_REF:0000019, GO:0050801=GO_REF:0000019, GO:0071314=GO_REF:0000019, GO:0010841=PMID:18329818, GO:0010700=GO_REF:0000019, GO:0033494=GO_REF:0000019, GO:0005179=PMID:7585095, GO:0016101=GO_REF:0000019, GO:0007631=GO_REF:0000019, GO:0045472=GO_REF:0000019, GO:0008284=GO_REF:0000019, GO:0030325=GO_REF:0000019, GO:0030324=GO_REF:0000019, GO:0045471=GO_REF:0000019, GO:0030819=GO_REF:0000019, GO:0007268=PMID:7477348, GO:0045776=GO_REF:0000019, GO:0090280=GO_REF:0000019, GO:0005737=GO_REF:0000019, GO:0006954=PMID:18559919, GO:0043196=GO_REF:0000019, GO:0001963=PMID:12895416, GO:0043204=GO_REF:0000019, GO:0060456=GO_REF:0000019, GO:0051461=GO_REF:0000019, GO:2000987=GO_REF:0000019, GO:0051464=PMID:18329818, GO:0070093=GO_REF:0000019, GO:0035902=GO_REF:0000019, GO:0051430=GO_REF:0000019, GO:0035774=GO_REF:0000019, GO:0042493=GO_REF:0000019, GO:0051431=GO_REF:0000019, GO:0005102=PMID:7477348, GO:0005576=Reactome:REACT_22268, GO:0021854=GO_REF:0000019, GO:0010628=GO_REF:0000019, GO:0007165=PMID:7867564, GO:0042322=PMID:18329818, GO:0010629=GO_REF:0000019, GO:0001934=GO_REF:0000019, GO:0048265=GO_REF:0000019, GO:0008628=GO_REF:0000019, GO:0017045=GO_REF:0000019, GO:0071549=GO_REF:0000019} P06850 Corticoliberin protein 20090114 {GO:0005515=IPI, GO:0043627=IEA, GO:0032811=IEA, GO:0033685=IEA, GO:0006704=IEA, GO:2000310=IDA, GO:2000854=IEA, GO:0005615=IDA, GO:0007611=TAS, GO:0060548=IEA, GO:0005184=TAS, GO:0010942=IEA, GO:0035641=IEA, GO:0008306=IEA, GO:0014062=IEA, GO:0051412=IEA, GO:0007565=IDA, GO:0007567=TAS, GO:0007616=IEA, GO:0050801=IEA, GO:0071314=IEA, GO:0010841=NAS, GO:0010700=IEA, GO:0033494=IEA, GO:0005179=TAS, GO:0016101=IEA, GO:0007631=IEA, GO:0045472=IEA, GO:0008284=IEA, GO:0030325=IEA, GO:0030324=IEA, GO:0045471=IEA, GO:0030819=IEA, GO:0007268=TAS, GO:0045776=IEA, GO:0090280=IEA, GO:0005737=IEA, GO:0006954=IDA, GO:0043196=IEA, GO:0001963=IDA, GO:0043204=IEA, GO:0060456=IEA, GO:0051461=IEA, GO:2000987=IEA, GO:0051464=IDA, GO:0070093=IEA, GO:0035902=IEA, GO:0051430=IEA, GO:0035774=IEA, GO:0042493=IEA, GO:0051431=IEA, GO:0005102=TAS, GO:0005576=TAS, GO:0021854=IEA, GO:0010628=IEA, GO:0007165=TAS, GO:0042322=NAS, GO:0010629=IEA, GO:0001934=IEA, GO:0048265=IEA, GO:0008628=IEA, GO:0017045=IEA, GO:0071549=IEA} adrenal gland development, associative learning, cellular response to cocaine, cellular response to dexamethasone stimulus, diterpenoid metabolic process, feeding behavior, female pregnancy, ferulate metabolic process, glucocorticoid biosynthetic process, hormone-mediated apoptotic signaling pathway, hypothalamus development, inflammatory response, ion homeostasis, learning or memory, locomotory exploration behavior, long-term memory, lung development, negative regulation of blood pressure, negative regulation of cell death, negative regulation of circadian sleep/wake cycle, REM sleep, negative regulation of epinephrine secretion, negative regulation of gene expression, negative regulation of glucagon secretion, negative regulation of luteinizing hormone secretion, negative regulation of norepinephrine secretion, parturition, positive regulation of behavioral fear response, positive regulation of cAMP biosynthetic process, positive regulation of calcium ion import, positive regulation of cell death, positive regulation of cell proliferation, positive regulation of circadian sleep/wake cycle, wakefulness, positive regulation of corticosterone secretion, positive regulation of corticotropin secretion, positive regulation of cortisol secretion, positive regulation of digestive system process, positive regulation of gene expression, positive regulation of insulin secretion involved in cellular response to glucose stimulus, positive regulation of protein phosphorylation, regulation of N-methyl-D-aspartate selective glutamate receptor activity, regulation of serotonin secretion, response to corticosterone stimulus, response to drug, response to estrogen stimulus, response to ethanol, response to ether, response to immobilization stress, response to pain, signal transduction, synaptic transmission, synaptic transmission, dopaminergic cytoplasm, extracellular region, extracellular space, perikaryon, varicosity corticotropin-releasing hormone activity, corticotropin-releasing hormone receptor 1 binding, corticotropin-releasing hormone receptor 2 binding, hormone activity, neuropeptide hormone activity, protein binding, receptor binding Human CRHBP UniProtKB UniProtKB {GO:0005515=PMID:18234674, GO:0005783=PMID:21624661, GO:0051424=PMID:1846945, GO:2000310=GO_REF:0000024, GO:0031045=GO_REF:0000024, GO:0005634=GO_REF:0000024, GO:0005615=PMID:18559919, GO:0030425=GO_REF:0000024, GO:0005622=GO_REF:0000024, GO:0045055=PMID:21624661, GO:0035865=PMID:21624661, GO:0006954=PMID:18559919, GO:0071392=PMID:15345745, GO:0001963=GO_REF:0000024, GO:0043196=GO_REF:0000024, GO:0071356=PMID:15345745, GO:0007611=PMID:7477348, GO:0071277=GO_REF:0000024, GO:0007610=GO_REF:0000024, GO:0043204=GO_REF:0000024, GO:0043679=GO_REF:0000024, GO:0030141=PMID:21624661, GO:0042277=GO_REF:0000024, GO:0007565=PMID:18559919, GO:0005794=PMID:21624661, GO:0005771=GO_REF:0000024, GO:0005874=GO_REF:0000024, GO:0071314=GO_REF:0000024, GO:0071391=PMID:15345745, GO:0033554=PMID:21039637, GO:0035690=GO_REF:0000024, GO:0097211=GO_REF:0000024, GO:0002125=GO_REF:0000024, GO:0007165=PMID:7477348, GO:0009755=PMID:18234674, GO:0048149=PMID:21039637, GO:0050795=PMID:21039637, GO:0051459=PMID:13150566, GO:0042445=GO_REF:0000019, GO:0005767=GO_REF:0000024, GO:0071320=GO_REF:0000024} P24387 Corticotropin-releasing factor-binding protein protein 20120111 {GO:0005515=IPI, GO:0005783=IDA, GO:0051424=IDA, GO:2000310=ISS, GO:0031045=ISS, GO:0005634=ISS, GO:0005615=IDA, GO:0030425=ISS, GO:0005622=ISS, GO:0045055=IDA, GO:0035865=IDA, GO:0006954=IDA, GO:0071392=IDA, GO:0001963=ISS, GO:0043196=ISS, GO:0071356=IDA, GO:0007611=TAS, GO:0071277=ISS, GO:0007610=ISS, GO:0043204=ISS, GO:0043679=ISS, GO:0030141=IDA, GO:0042277=ISS, GO:0007565=IDA, GO:0005794=IDA, GO:0005771=ISS, GO:0005874=ISS, GO:0071314=ISS, GO:0071391=IDA, GO:0033554=IMP, GO:0035690=ISS, GO:0097211=ISS, GO:0002125=ISS, GO:0007165=TAS, GO:0009755=IDA, GO:0048149=IMP, GO:0050795=IMP, GO:0051459=IDA, GO:0042445=IEA, GO:0005767=ISS, GO:0071320=ISS} behavior, behavioral response to ethanol, cellular response to cAMP, cellular response to calcium ion, cellular response to cocaine, cellular response to drug, cellular response to estradiol stimulus, cellular response to estrogen stimulus, cellular response to gonadotropin-releasing hormone, cellular response to potassium ion, cellular response to stress, cellular response to tumor necrosis factor, female pregnancy, hormone metabolic process, hormone-mediated signaling pathway, inflammatory response, learning or memory, maternal aggressive behavior, regulated secretory pathway, regulation of N-methyl-D-aspartate selective glutamate receptor activity, regulation of behavior, regulation of corticotropin secretion, signal transduction, synaptic transmission, dopaminergic Golgi apparatus, axon terminus, dendrite, dense core granule, endoplasmic reticulum, extracellular space, intracellular, microtubule, multivesicular body, nucleus, perikaryon, secondary lysosome, secretory granule, varicosity corticotropin-releasing hormone binding, peptide binding, protein binding Human UniProtKB:Q60571 CRHR1 IntAct UniProtKB {GO:0005515=PMID:18801728, GO:0005802=GO_REF:0000019, GO:0015056=GO_REF:0000019, GO:0005886=Reactome:REACT_22268, GO:0032811=GO_REF:0000019, GO:0051424=GO_REF:0000019, GO:0032099=GO_REF:0000019, GO:0048148=GO_REF:0000019, GO:0007200=GO_REF:0000019, GO:0060291=GO_REF:0000019, GO:0007204=GO_REF:0000019, GO:0032403=GO_REF:0000019, GO:0030425=GO_REF:0000019, GO:0007190=PMID:10598591, GO:0001965=GO_REF:0000019, GO:0006955=PMID:7692441, GO:0007218=GO_REF:0000019, GO:0030855=GO_REF:0000019, GO:0043025=GO_REF:0000019, GO:0007613=GO_REF:0000019, GO:0043404=GO_REF:0000019, GO:0035641=GO_REF:0000019, GO:0001666=GO_REF:0000019, GO:0035902=GO_REF:0000019, GO:0007565=PMID:7585095, GO:0007567=PMID:10598591, GO:0004930=GO_REF:0000002, GO:0005771=GO_REF:0000019, GO:1901215=GO_REF:0000019, GO:0045177=GO_REF:0000019, GO:0021854=GO_REF:0000019, GO:0031982=GO_REF:0000019, GO:0043306=GO_REF:0000019, GO:0033267=GO_REF:0000019, GO:0007186=PMID:8243652, GO:0016020=GO_REF:0000002, GO:0005887=PMID:10598591, GO:0008542=GO_REF:0000019, GO:0007188=PMID:7692441, GO:0042755=GO_REF:0000019, GO:0007189=GO_REF:0000019, GO:0016021=GO_REF:0000002, GO:0048266=GO_REF:0000019} P34998 Corticotropin-releasing factor receptor 1 protein 20130415 {GO:0005515=IPI, GO:0005802=IEA, GO:0015056=IEA, GO:0005886=TAS, GO:0032811=IEA, GO:0051424=IEA, GO:0032099=IEA, GO:0048148=IEA, GO:0007200=IEA, GO:0060291=IEA, GO:0007204=IEA, GO:0032403=IEA, GO:0030425=IEA, GO:0007190=TAS, GO:0001965=IEA, GO:0006955=TAS, GO:0007218=IEA, GO:0030855=IEA, GO:0043025=IEA, GO:0007613=IEA, GO:0043404=IEA, GO:0035641=IEA, GO:0001666=IEA, GO:0035902=IEA, GO:0007565=NAS, GO:0007567=TAS, GO:0004930=IEA, GO:0005771=IEA, GO:1901215=IEA, GO:0045177=IEA, GO:0021854=IEA, GO:0031982=IEA, GO:0043306=IEA, GO:0033267=IEA, GO:0007186=TAS, GO:0016020=IEA, GO:0005887=TAS, GO:0008542=IEA, GO:0007188=TAS, GO:0042755=IEA, GO:0007189=IEA, GO:0016021=IEA, GO:0048266=IEA} G-protein coupled receptor signaling pathway, activation of adenylate cyclase activity, adenylate cyclase-activating G-protein coupled receptor signaling pathway, adenylate cyclase-modulating G-protein coupled receptor signaling pathway, behavioral response to cocaine, behavioral response to pain, eating behavior, elevation of cytosolic calcium ion concentration, epithelial cell differentiation, female pregnancy, hypothalamus development, immune response, locomotory exploration behavior, long-term synaptic potentiation, memory, negative regulation of appetite, negative regulation of epinephrine secretion, negative regulation of neuron death, neuropeptide signaling pathway, parturition, phospholipase C-activating G-protein coupled receptor signaling pathway, positive regulation of mast cell degranulation, response to hypoxia, response to immobilization stress, visual learning apical part of cell, axon part, dendrite, integral to membrane, integral to plasma membrane, membrane, multivesicular body, neuronal cell body, plasma membrane, trans-Golgi network, vesicle G-protein alpha-subunit binding, G-protein coupled receptor activity, corticotrophin-releasing factor receptor activity, corticotropin-releasing hormone binding, corticotropin-releasing hormone receptor activity, protein binding, protein complex binding Human UniProtKB:P06850 CRHR2 Reactome UniProtKB {GO:0005515=PMID:11329063, GO:0015056=GO_REF:0000019, GO:0005794=GO_REF:0000019, GO:0005886=Reactome:REACT_22268, GO:0009986=GO_REF:0000019, GO:0004930=GO_REF:0000038, GO:0005783=GO_REF:0000019, GO:0005179=GO_REF:0000019, GO:0005887=PMID:8536644, GO:0016525=GO_REF:0000019, GO:0043950=GO_REF:0000019, GO:0007188=PMID:8536644, GO:0016021=GO_REF:0000038, GO:0043951=GO_REF:0000019} Q13324 Corticotropin-releasing factor receptor 2 protein 20090511 {GO:0005515=IPI, GO:0015056=IEA, GO:0005794=IEA, GO:0005886=TAS, GO:0009986=IEA, GO:0004930=IEA, GO:0005783=IEA, GO:0005179=IEA, GO:0005887=TAS, GO:0016525=IEA, GO:0043950=IEA, GO:0007188=TAS, GO:0016021=IEA, GO:0043951=IEA} adenylate cyclase-modulating G-protein coupled receptor signaling pathway, negative regulation of angiogenesis, negative regulation of cAMP-mediated signaling, positive regulation of cAMP-mediated signaling Golgi apparatus, cell surface, endoplasmic reticulum, integral to membrane, integral to plasma membrane, plasma membrane G-protein coupled receptor activity, corticotrophin-releasing factor receptor activity, hormone activity, protein binding Human CRIM1 GOC UniProtKB {GO:0005886=GO_REF:0000039, GO:0004867=GO_REF:0000002, GO:0005010=PMID:10642437, GO:0048009=PMID:10642437, GO:0005576=GO_REF:0000039, GO:0016021=GO_REF:0000037, GO:0001558=GO_REF:0000002, GO:0007399=PMID:10642437, GO:0005520=GO_REF:0000002} Q9NZV1 Cysteine-rich motor neuron 1 protein protein 20130413 {GO:0005886=IEA, GO:0004867=IEA, GO:0005010=TAS, GO:0048009=TAS, GO:0005576=IEA, GO:0016021=IEA, GO:0001558=IEA, GO:0007399=TAS, GO:0005520=IEA} insulin-like growth factor receptor signaling pathway, nervous system development, regulation of cell growth extracellular region, integral to membrane, plasma membrane insulin-like growth factor binding, insulin-like growth factor-activated receptor activity, serine-type endopeptidase inhibitor activity Human CRIP1 UniProtKB UniProtKB {GO:0010468=PMID:7999070, GO:0007507=PMID:7999070, GO:0042277=PMID:18670594, GO:0006955=PMID:20415737, GO:0003680=PMID:20108983, GO:0008301=PMID:20108983, GO:0008283=PMID:9126610, GO:0060741=PMID:9507743, GO:0008270=PMID:9126610, GO:0010043=PMID:7999070} P50238 Cysteine-rich protein 1 protein 20110822 {GO:0010468=IEP, GO:0007507=TAS, GO:0042277=IDA, GO:0006955=IEP, GO:0003680=IDA, GO:0008301=IDA, GO:0008283=TAS, GO:0060741=IEP, GO:0008270=IDA, GO:0010043=IDA} cell proliferation, heart development, immune response, prostate gland stromal morphogenesis, regulation of gene expression, response to zinc ion AT DNA binding, DNA binding, bending, peptide binding, zinc ion binding Human CRIP2 ENSEMBL UniProtKB {GO:0030097=GO_REF:0000019, GO:0008284=GO_REF:0000019, GO:0008270=GO_REF:0000002, GO:0005938=GO_REF:0000019} P52943 Cysteine-rich protein 2 protein 20130413 {GO:0030097=IEA, GO:0008284=IEA, GO:0008270=IEA, GO:0005938=IEA} hemopoiesis, positive regulation of cell proliferation cell cortex zinc ion binding Human Ensembl:ENSMUSP00000081943 CRIPAK IntAct UniProtKB {GO:0005515=PMID:16278681, GO:0043627=PMID:16278681, GO:0005737=PMID:16278681, GO:0051493=PMID:16278681, GO:0005886=PMID:16278681, GO:0005783=PMID:16278681, GO:0005634=PMID:16278681, GO:0006469=PMID:16278681, GO:0033147=PMID:16278681} Q8N1N5 Cysteine-rich PAK1 inhibitor protein 20130415 {GO:0005515=IPI, GO:0043627=IDA, GO:0005737=IDA, GO:0051493=IDA, GO:0005886=IDA, GO:0005783=IDA, GO:0005634=IDA, GO:0006469=IDA, GO:0033147=IDA} negative regulation of intracellular estrogen receptor signaling pathway, negative regulation of protein kinase activity, regulation of cytoskeleton organization, response to estrogen stimulus cytoplasm, endoplasmic reticulum, nucleus, plasma membrane protein binding Human UniProtKB:Q13153 CRIPT UniProtKB UniProtKB {GO:0005737=GO_REF:0000039, GO:0030054=GO_REF:0000037, GO:0043198=GO_REF:0000019, GO:0043025=GO_REF:0000019, GO:0014069=GO_REF:0000019, GO:0031122=GO_REF:0000019, GO:0030165=GO_REF:0000019, GO:0032403=GO_REF:0000019, GO:0045184=GO_REF:0000019} Q9P021 Cysteine-rich PDZ-binding protein protein 20130413 {GO:0005737=IEA, GO:0030054=IEA, GO:0043198=IEA, GO:0043025=IEA, GO:0014069=IEA, GO:0031122=IEA, GO:0030165=IEA, GO:0032403=IEA, GO:0045184=IEA} cytoplasmic microtubule organization, establishment of protein localization cell junction, cytoplasm, dendritic shaft, neuronal cell body, postsynaptic density PDZ domain binding, protein complex binding Human UniProtKB-SubCell:SL-0086 CRISP3 UniProtKB UniProtKB {GO:0003674=GO_REF:0000015, GO:0045087=PMID:12223513, GO:0005578=PMID:12223513, GO:0042581=PMID:12223513, GO:0006952=PMID:12647793, GO:0005576=PMID:12009203} P54108 Cysteine-rich secretory protein 3 protein 20061026 {GO:0003674=ND, GO:0045087=NAS, GO:0005578=NAS, GO:0042581=IDA, GO:0006952=NAS, GO:0005576=IDA} defense response, innate immune response extracellular region, proteinaceous extracellular matrix, specific granule molecular_function Human CRISPLD2 LIFEdb UniProtKB {GO:0030133=GO_REF:0000054, GO:0031012=GO_REF:0000019, GO:0030198=GO_REF:0000019, GO:0005576=GO_REF:0000039, GO:0008201=GO_REF:0000019} Q9H0B8 Cysteine-rich secretory protein LCCL domain-containing 2 protein 20100607 {GO:0030133=IDA, GO:0031012=IEA, GO:0030198=IEA, GO:0005576=IEA, GO:0008201=IEA} extracellular matrix organization extracellular matrix, extracellular region, transport vesicle heparin binding Human CRK IntAct UniProtKB {GO:0008286=Reactome:REACT_498, GO:0005515=PMID:23275563, GO:0048011=Reactome:REACT_11061, GO:0035020=GO_REF:0000019, GO:0005886=GO_REF:0000039, GO:0048013=PMID:11870224, GO:0006357=PMID:10748058, GO:0045309=GO_REF:0000019, GO:0030168=Reactome:REACT_798, GO:0005634=PMID:10748058, GO:0005829=Reactome:REACT_160134, GO:0000186=Reactome:REACT_12005, GO:0005737=PMID:11870224, GO:0046875=PMID:11870224, GO:0007596=Reactome:REACT_604, GO:0045087=Reactome:REACT_6802, GO:0005070=GO_REF:0000019, GO:0032956=PMID:11870224, GO:0032319=PMID:11870224, GO:0038096=Reactome:REACT_160123, GO:0042169=PMID:9472046} P46108 Adapter molecule crk protein 20130415 {GO:0008286=TAS, GO:0005515=IPI, GO:0048011=TAS, GO:0035020=IEA, GO:0005886=IEA, GO:0048013=IDA, GO:0006357=TAS, GO:0045309=IEA, GO:0030168=TAS, GO:0005634=TAS, GO:0005829=TAS, GO:0000186=TAS, GO:0005737=IC, GO:0046875=IPI, GO:0007596=TAS, GO:0045087=TAS, GO:0005070=IEA, GO:0032956=IDA, GO:0032319=IDA, GO:0038096=TAS, GO:0042169=IPI} Fc-gamma receptor signaling pathway involved in phagocytosis, activation of MAPKK activity, blood coagulation, ephrin receptor signaling pathway, innate immune response, insulin receptor signaling pathway, neurotrophin TRK receptor signaling pathway, platelet activation, regulation of Rac protein signal transduction, regulation of Rho GTPase activity, regulation of actin cytoskeleton organization, regulation of transcription from RNA polymerase II promoter cytoplasm, cytosol, nucleus, plasma membrane SH2 domain binding, SH3/SH2 adaptor activity, ephrin receptor binding, protein binding, protein phosphorylated amino acid binding Human UniProtKB:P54253 CRKL IntAct UniProtKB {GO:0005515=PMID:16284401, GO:0048011=Reactome:REACT_11061, GO:0001568=GO_REF:0000019, GO:0007254=PMID:8798523, GO:0048538=GO_REF:0000019, GO:0007265=PMID:8798523, GO:0009952=GO_REF:0000019, GO:0005829=Reactome:REACT_23925, GO:0007507=GO_REF:0000019, GO:0035556=PMID:8361759, GO:0060017=GO_REF:0000019, GO:0000186=Reactome:REACT_12005, GO:0005070=PMID:8798523, GO:0009887=GO_REF:0000019, GO:0004871=PMID:8798523, GO:0005768=Reactome:REACT_12015} P46109 Crk-like protein protein 20130415 {GO:0005515=IPI, GO:0048011=TAS, GO:0001568=IEA, GO:0007254=TAS, GO:0048538=IEA, GO:0007265=TAS, GO:0009952=IEA, GO:0005829=TAS, GO:0007507=IEA, GO:0035556=TAS, GO:0060017=IEA, GO:0000186=TAS, GO:0005070=TAS, GO:0009887=IEA, GO:0004871=TAS, GO:0005768=TAS} JNK cascade, Ras protein signal transduction, activation of MAPKK activity, anterior/posterior pattern specification, blood vessel development, heart development, intracellular signal transduction, neurotrophin TRK receptor signaling pathway, organ morphogenesis, parathyroid gland development, thymus development cytosol, endosome SH3/SH2 adaptor activity, protein binding, signal transducer activity Human UniProtKB:Q9EQG6 CRLF1 BHF-UCL UniProtKB {GO:0005515=PMID:10966616, GO:0001657=GO_REF:0000019, GO:0008284=PMID:10966616, GO:0005886=GO_REF:0000052, GO:0046982=PMID:10966616, GO:0042517=PMID:10966616, GO:2000672=GO_REF:0000019, GO:0005615=PMID:9686600, GO:0005125=PMID:10966616, GO:0097058=PMID:10966616, GO:0005127=PMID:10966616, GO:0043524=PMID:10966616, GO:0005737=GO_REF:0000052, GO:0019955=PMID:15034937, GO:0004872=PMID:9686600} O75462 Cytokine receptor-like factor 1 protein 20120404 {GO:0005515=IPI, GO:0001657=IEA, GO:0008284=IDA, GO:0005886=IDA, GO:0046982=IDA, GO:0042517=IDA, GO:2000672=IEA, GO:0005615=TAS, GO:0005125=IDA, GO:0097058=IDA, GO:0005127=IDA, GO:0043524=IDA, GO:0005737=IDA, GO:0019955=IPI, GO:0004872=TAS} negative regulation of motor neuron apoptotic process, negative regulation of neuron apoptotic process, positive regulation of cell proliferation, positive regulation of tyrosine phosphorylation of Stat3 protein, ureteric bud development CRLF-CLCF1 complex, cytoplasm, extracellular space, plasma membrane ciliary neurotrophic factor receptor binding, cytokine activity, cytokine binding, protein binding, protein heterodimerization activity, receptor activity Human CRLF2 UniProtKB UniProtKB {GO:0005886=GO_REF:0000039, GO:0005576=GO_REF:0000039, GO:0016021=GO_REF:0000037} Q9HC73 Cytokine receptor-like factor 2 protein 20130413 {GO:0005886=IEA, GO:0005576=IEA, GO:0016021=IEA} extracellular region, integral to membrane, plasma membrane Human UniProtKB-SubCell:SL-0039 CRLF3 UniProtKB UniProtKB {GO:0030308=PMID:19427400, GO:0005737=PMID:19427400, GO:0045944=PMID:19427400, GO:0045893=PMID:19427400, GO:0045749=PMID:19427400, GO:0071158=PMID:19427400, GO:0046427=PMID:19427400} Q8IUI8 Cytokine receptor-like factor 3 protein 20101115 {GO:0030308=IDA, GO:0005737=IDA, GO:0045944=IDA, GO:0045893=IDA, GO:0045749=IMP, GO:0071158=IDA, GO:0046427=IDA} negative regulation of S phase of mitotic cell cycle, negative regulation of cell growth, positive regulation of JAK-STAT cascade, positive regulation of cell cycle arrest, positive regulation of transcription from RNA polymerase II promoter, positive regulation of transcription, DNA-dependent cytoplasm Human CRLS1 Reactome UniProtKB {GO:0016780=GO_REF:0000002, GO:0016020=GO_REF:0000002, GO:0036148=Reactome:REACT_121324, GO:0005743=Reactome:REACT_121361, GO:0044281=Reactome:REACT_111217, GO:0032049=Reactome:REACT_120920, GO:0016021=GO_REF:0000037, GO:0008654=GO_REF:0000002, GO:0006644=Reactome:REACT_120870, GO:0046474=Reactome:REACT_121401} Q9UJA2 Cardiolipin synthase protein 20130301 {GO:0016780=IEA, GO:0016020=IEA, GO:0036148=TAS, GO:0005743=TAS, GO:0044281=TAS, GO:0032049=TAS, GO:0016021=IEA, GO:0008654=IEA, GO:0006644=TAS, GO:0046474=TAS} cardiolipin biosynthetic process, glycerophospholipid biosynthetic process, phosphatidylglycerol acyl-chain remodeling, phospholipid biosynthetic process, phospholipid metabolic process, small molecule metabolic process integral to membrane, membrane, mitochondrial inner membrane phosphotransferase activity, for other substituted phosphate groups Human CRMP1 HPA UniProtKB {GO:0005515=PMID:16169070, GO:0005815=GO_REF:0000039, GO:0016812=GO_REF:0000002, GO:0005819=GO_REF:0000039, GO:0030425=GO_REF:0000019, GO:0043231=GO_REF:0000052, GO:0007399=PMID:8973361, GO:0005829=Reactome:REACT_19321, GO:0005737=GO_REF:0000052, GO:0006139=PMID:8973361, GO:0007411=Reactome:REACT_18266, GO:0043025=GO_REF:0000019, GO:0006208=GO_REF:0000002} Q14194 Dihydropyrimidinase-related protein 1 protein 20110516 {GO:0005515=IPI, GO:0005815=IEA, GO:0016812=IEA, GO:0005819=IEA, GO:0030425=IEA, GO:0043231=IDA, GO:0007399=TAS, GO:0005829=TAS, GO:0005737=IDA, GO:0006139=TAS, GO:0007411=TAS, GO:0043025=IEA, GO:0006208=IEA} axon guidance, nervous system development, nucleobase-containing compound metabolic process, pyrimidine nucleobase catabolic process cytoplasm, cytosol, dendrite, intracellular membrane-bounded organelle, microtubule organizing center, neuronal cell body, spindle hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides, protein binding Human CRNKL1 UniProtKB UniProtKB {GO:0005622=GO_REF:0000002, GO:0000245=PMID:12084575, GO:0006396=GO_REF:0000002, GO:0005737=GO_REF:0000039, GO:0016607=GO_REF:0000039, GO:0000398=PMID:11991638, GO:0003723=PMID:12084575, GO:0005681=PMID:11991638, GO:0071013=PMID:11991638} Q9BZJ0 Crooked neck-like protein 1 protein 20110302 {GO:0005622=IEA, GO:0000245=IDA, GO:0006396=IEA, GO:0005737=IEA, GO:0016607=IEA, GO:0000398=IC, GO:0003723=IDA, GO:0005681=IDA, GO:0071013=IDA} RNA processing, mRNA splicing, via spliceosome, spliceosomal complex assembly catalytic step 2 spliceosome, cytoplasm, intracellular, nuclear speck, spliceosomal complex RNA binding Human CRNN UniProtKB UniProtKB {GO:0005737=PMID:14967811, GO:0016337=PMID:2631556, GO:0009408=PMID:11606197, GO:0016020=PMID:2980212, GO:0005509=PMID:11056050} Q9UBG3 Cornulin protein 20040809 {GO:0005737=TAS, GO:0016337=IDA, GO:0009408=IDA, GO:0016020=IDA, GO:0005509=NAS} cell-cell adhesion, response to heat cytoplasm, membrane calcium ion binding Human CROCC HPA UniProtKB {GO:0005515=PMID:18086858, GO:0005813=GO_REF:0000052, GO:0005886=GO_REF:0000052, GO:0005814=GO_REF:0000024, GO:0015629=GO_REF:0000052, GO:0051297=PMID:16203858, GO:0005737=GO_REF:0000052, GO:0007049=GO_REF:0000037, GO:0008104=PMID:18086858, GO:0005198=GO_REF:0000024, GO:0035253=GO_REF:0000024, GO:0030030=GO_REF:0000037, GO:0019894=GO_REF:0000024} Q5TZA2 Rootletin protein 20101115 {GO:0005515=IPI, GO:0005813=IDA, GO:0005886=IDA, GO:0005814=ISS, GO:0015629=IDA, GO:0051297=IDA, GO:0005737=IDA, GO:0007049=IEA, GO:0008104=IMP, GO:0005198=ISS, GO:0035253=ISS, GO:0030030=IEA, GO:0019894=ISS} cell cycle, cell projection organization, centrosome organization, protein localization actin cytoskeleton, centriole, centrosome, ciliary rootlet, cytoplasm, plasma membrane kinesin binding, protein binding, structural molecule activity Human CROT HPA UniProtKB {GO:0016746=GO_REF:0000038, GO:0006635=PMID:21619872, GO:0005782=Reactome:REACT_16985, GO:0005102=PMID:20178365, GO:0044281=Reactome:REACT_111217, GO:0008458=PMID:21619872, GO:0006091=PMID:10486279, GO:0043231=GO_REF:0000052, GO:0005739=GO_REF:0000019, GO:0006810=GO_REF:0000037, GO:0006631=PMID:21619872, GO:0051791=PMID:10486279, GO:0033540=Reactome:REACT_17017, GO:0015908=GO_REF:0000019, GO:0044255=Reactome:REACT_16957, GO:0005777=PMID:10486279} Q9UKG9 Peroxisomal carnitine O-octanoyltransferase protein 20100326 {GO:0016746=IEA, GO:0006635=IDA, GO:0005782=TAS, GO:0005102=IPI, GO:0044281=TAS, GO:0008458=IDA, GO:0006091=IDA, GO:0043231=IDA, GO:0005739=IEA, GO:0006810=IEA, GO:0006631=IMP, GO:0051791=IDA, GO:0033540=TAS, GO:0015908=IEA, GO:0044255=TAS, GO:0005777=NAS} cellular lipid metabolic process, fatty acid beta-oxidation, fatty acid beta-oxidation using acyl-CoA oxidase, fatty acid metabolic process, fatty acid transport, generation of precursor metabolites and energy, medium-chain fatty acid metabolic process, small molecule metabolic process, transport intracellular membrane-bounded organelle, mitochondrion, peroxisomal matrix, peroxisome carnitine O-octanoyltransferase activity, receptor binding, transferase activity, transferring acyl groups Human CRP BHF-UCL UniProtKB {GO:0033265=PMID:2477488, GO:0005515=PMID:17785206, GO:0051258=GO_REF:0000019, GO:0005886=GO_REF:0000019, GO:0045471=GO_REF:0000019, GO:0030175=GO_REF:0000019, GO:0005615=GO_REF:0000019, GO:0042803=GO_REF:0000019, GO:0046872=GO_REF:0000037, GO:0030426=GO_REF:0000019, GO:0005739=GO_REF:0000019, GO:0006954=PMID:10408362, GO:0015485=GO_REF:0000019, GO:0006958=GO_REF:0000019, GO:0071277=GO_REF:0000019, GO:0071333=GO_REF:0000019, GO:0008228=PMID:2477488, GO:1900006=GO_REF:0000019, GO:0010288=GO_REF:0000019, GO:0001666=GO_REF:0000019, GO:0010745=PMID:18322245, GO:0007568=GO_REF:0000019, GO:0030169=PMID:18322245, GO:0005576=PMID:14718574, GO:0006953=PMID:2477488, GO:0010888=PMID:18322245, GO:0051637=PMID:2477488, GO:0042060=GO_REF:0000019} P02741 C-reactive protein protein 20080707 {GO:0033265=TAS, GO:0005515=IPI, GO:0051258=IEA, GO:0005886=IEA, GO:0045471=IEA, GO:0030175=IEA, GO:0005615=IEA, GO:0042803=IEA, GO:0046872=IEA, GO:0030426=IEA, GO:0005739=IEA, GO:0006954=TAS, GO:0015485=IEA, GO:0006958=IEA, GO:0071277=IEA, GO:0071333=IEA, GO:0008228=TAS, GO:1900006=IEA, GO:0010288=IEA, GO:0001666=IEA, GO:0010745=IDA, GO:0007568=IEA, GO:0030169=IDA, GO:0005576=NAS, GO:0006953=TAS, GO:0010888=IDA, GO:0051637=TAS, GO:0042060=IEA} acute-phase response, aging, cellular response to calcium ion, cellular response to glucose stimulus, complement activation, classical pathway, inflammatory response, negative regulation of lipid storage, negative regulation of macrophage derived foam cell differentiation, opsonization, positive regulation of dendrite development, protein polymerization, response to ethanol, response to hypoxia, response to lead ion, wound healing extracellular region, extracellular space, filopodium, growth cone, mitochondrion, plasma membrane Gram-positive bacterial cell surface binding, cholesterol binding, choline binding, low-density lipoprotein particle binding, metal ion binding, protein binding, protein homodimerization activity Human CRTAM HGNC UniProtKB {GO:0008037=PMID:15811952, GO:0051606=PMID:15811952, GO:0005886=Reactome:REACT_11097, GO:0001913=PMID:15811952, GO:0045954=PMID:15811952, GO:0050776=Reactome:REACT_11152, GO:0005102=PMID:15811952, GO:0002860=PMID:15811952, GO:0002355=PMID:15811952, GO:0050798=PMID:15811952, GO:0050715=PMID:15811952, GO:0016021=GO_REF:0000037} O95727 Cytotoxic and regulatory T-cell molecule protein 20060628 {GO:0008037=IDA, GO:0051606=IDA, GO:0005886=TAS, GO:0001913=IDA, GO:0045954=IDA, GO:0050776=TAS, GO:0005102=IPI, GO:0002860=IDA, GO:0002355=IDA, GO:0050798=IDA, GO:0050715=IDA, GO:0016021=IEA} T cell mediated cytotoxicity, activated T cell proliferation, cell recognition, detection of stimulus, detection of tumor cell, positive regulation of cytokine secretion, positive regulation of natural killer cell mediated cytotoxicity, positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, regulation of immune response integral to membrane, plasma membrane receptor binding Human CRTAP Reactome UniProtKB {GO:0018400=GO_REF:0000019, GO:0030198=Reactome:REACT_118779, GO:0005578=GO_REF:0000039, GO:0005788=Reactome:REACT_120939, GO:0007283=GO_REF:0000019} O75718 Cartilage-associated protein protein 20120416 {GO:0018400=IEA, GO:0030198=TAS, GO:0005578=IEA, GO:0005788=TAS, GO:0007283=IEA} extracellular matrix organization, peptidyl-proline hydroxylation to 3-hydroxy-L-proline, spermatogenesis endoplasmic reticulum lumen, proteinaceous extracellular matrix Human CRTC1 HPA UniProtKB {GO:0005515=PMID:14506290, GO:0032793=GO_REF:0000002, GO:0008140=PMID:14536081, GO:0005737=GO_REF:0000052, GO:0005886=GO_REF:0000052, GO:0051289=GO_REF:0000002, GO:0045944=PMID:14536081, GO:0019048=GO_REF:0000037, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0006351=GO_REF:0000037} Q6UUV9 CREB-regulated transcription coactivator 1 protein 20101115 {GO:0005515=IPI, GO:0032793=IEA, GO:0008140=IDA, GO:0005737=IDA, GO:0005886=IDA, GO:0051289=IEA, GO:0045944=IDA, GO:0019048=IEA, GO:0005730=IDA, GO:0005634=IDA, GO:0006351=IEA} positive regulation of CREB transcription factor activity, positive regulation of transcription from RNA polymerase II promoter, protein homotetramerization, transcription, DNA-dependent, virus-host interaction cytoplasm, nucleolus, nucleus, plasma membrane cAMP response element binding protein binding, protein binding Human CRTC2 HPA UniProtKB {GO:0032793=GO_REF:0000002, GO:0008140=GO_REF:0000002, GO:0005737=GO_REF:0000002, GO:0051289=GO_REF:0000002, GO:0019048=GO_REF:0000037, GO:0006094=GO_REF:0000024, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0042593=GO_REF:0000024, GO:0006351=GO_REF:0000037} Q5T4K5 CREB-regulated transcription coactivator 2 protein 20111111 {GO:0032793=IEA, GO:0008140=IEA, GO:0005737=IEA, GO:0051289=IEA, GO:0019048=IEA, GO:0006094=ISS, GO:0005730=IDA, GO:0005634=IDA, GO:0042593=ISS, GO:0006351=IEA} gluconeogenesis, glucose homeostasis, positive regulation of CREB transcription factor activity, protein homotetramerization, transcription, DNA-dependent, virus-host interaction cytoplasm, nucleolus, nucleus cAMP response element binding protein binding NOT Human CRTC3 HPA UniProtKB {GO:0032793=GO_REF:0000002, GO:0008140=GO_REF:0000002, GO:0005737=GO_REF:0000052, GO:0051289=GO_REF:0000002, GO:0019048=GO_REF:0000037, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0006351=GO_REF:0000037} Q6UUV7 CREB-regulated transcription coactivator 3 protein 20110516 {GO:0032793=IEA, GO:0008140=IEA, GO:0005737=IDA, GO:0051289=IEA, GO:0019048=IEA, GO:0005730=IDA, GO:0005634=IDA, GO:0006351=IEA} positive regulation of CREB transcription factor activity, protein homotetramerization, transcription, DNA-dependent, virus-host interaction cytoplasm, nucleolus, nucleus cAMP response element binding protein binding Human CRX PINC UniProtKB {GO:0005667=GO_REF:0000019, GO:0003700=GO_REF:0000019, GO:0060041=GO_REF:0000019, GO:0005634=GO_REF:0000040, GO:0003677=GO_REF:0000002, GO:0006351=GO_REF:0000037, GO:0043565=GO_REF:0000002, GO:0043522=PMID:10887186, GO:0003682=GO_REF:0000019, GO:0045944=GO_REF:0000019, GO:0009887=PMID:9390563, GO:0007601=GO_REF:0000037, GO:0050896=GO_REF:0000037} O43186 Cone-rod homeobox protein protein 20031119 {GO:0005667=IEA, GO:0003700=IEA, GO:0060041=IEA, GO:0005634=IEA, GO:0003677=IEA, GO:0006351=IEA, GO:0043565=IEA, GO:0043522=IPI, GO:0003682=IEA, GO:0045944=IEA, GO:0009887=TAS, GO:0007601=IEA, GO:0050896=IEA} organ morphogenesis, positive regulation of transcription from RNA polymerase II promoter, response to stimulus, retina development in camera-type eye, transcription, DNA-dependent, visual perception nucleus, transcription factor complex DNA binding, chromatin binding, leucine zipper domain binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity Human CRY1 BHF-UCL UniProtKB {GO:0005515=PMID:9383998, GO:0000988=PMID:15147242, GO:0003904=PMID:8909283, GO:0019901=GO_REF:0000019, GO:0019902=PMID:9383998, GO:0009785=PMID:8909283, GO:0005634=GO_REF:0000039, GO:0000122=PMID:15147242, GO:0003677=PMID:9801304, GO:0006351=GO_REF:0000037, GO:0003914=PMID:8909283, GO:0005739=GO_REF:0000019, GO:0018298=GO_REF:0000037, GO:0009882=PMID:8909283, GO:0003690=PMID:9801304, GO:0006281=GO_REF:0000002, GO:0000166=GO_REF:0000037, GO:0007623=GO_REF:0000019, GO:0042752=GO_REF:0000024} Q16526 Cryptochrome-1 protein 20111104 {GO:0005515=IPI, GO:0000988=IDA, GO:0003904=IDA, GO:0019901=IEA, GO:0019902=IPI, GO:0009785=NAS, GO:0005634=IEA, GO:0000122=IDA, GO:0003677=TAS, GO:0006351=IEA, GO:0003914=IDA, GO:0005739=IEA, GO:0018298=IEA, GO:0009882=NAS, GO:0003690=IDA, GO:0006281=IEA, GO:0000166=IEA, GO:0007623=IEA, GO:0042752=ISS} DNA repair, blue light signaling pathway, circadian rhythm, negative regulation of transcription from RNA polymerase II promoter, protein-chromophore linkage, regulation of circadian rhythm, transcription, DNA-dependent mitochondrion, nucleus DNA (6-4) photolyase activity, DNA binding, blue light photoreceptor activity, deoxyribodipyrimidine photo-lyase activity, double-stranded DNA binding, nucleotide binding, phosphatase binding, protein binding, protein binding transcription factor activity, protein kinase binding Human CRY2 HPA UniProtKB {GO:0005515=PMID:9383998, GO:0000988=PMID:15147242, GO:0003904=PMID:8909283, GO:0005634=GO_REF:0000052, GO:0006606=GO_REF:0000019, GO:0005739=GO_REF:0000019, GO:0018298=GO_REF:0000037, GO:0005737=GO_REF:0000052, GO:0009882=PMID:8909283, GO:0000166=GO_REF:0000037, GO:0003697=PMID:12627958, GO:2000118=PMID:9753616, GO:0019902=PMID:9383998, GO:0009785=PMID:8909283, GO:0005576=PMID:9753616, GO:0000122=PMID:15147242, GO:0003677=PMID:12627958, GO:0006351=GO_REF:0000037, GO:0003913=GO_REF:0000002, GO:0003914=PMID:8909283, GO:0003684=PMID:12627958, GO:0006281=GO_REF:0000002, GO:0042752=GO_REF:0000019, GO:0007623=GO_REF:0000024, GO:0000719=PMID:12627958} Q49AN0 Cryptochrome-2 protein 20111111 {GO:0005515=IPI, GO:0000988=IDA, GO:0003904=IDA, GO:0005634=IDA, GO:0006606=IEA, GO:0005739=IEA, GO:0018298=IEA, GO:0005737=IDA, GO:0009882=NAS, GO:0000166=IEA, GO:0003697=IDA, GO:2000118=IDA, GO:0019902=IPI, GO:0009785=NAS, GO:0005576=IDA, GO:0000122=IDA, GO:0003677=IDA, GO:0006351=IEA, GO:0003913=IEA, GO:0003914=IDA, GO:0003684=IDA, GO:0006281=IEA, GO:0042752=IEA, GO:0007623=ISS, GO:0000719=IDA} DNA repair, blue light signaling pathway, circadian rhythm, negative regulation of transcription from RNA polymerase II promoter, photoreactive repair, protein import into nucleus, protein-chromophore linkage, regulation of circadian rhythm, regulation of sodium-dependent phosphate transport, transcription, DNA-dependent cytoplasm, extracellular region, mitochondrion, nucleus DNA (6-4) photolyase activity, DNA binding, DNA photolyase activity, blue light photoreceptor activity, damaged DNA binding, deoxyribodipyrimidine photo-lyase activity, nucleotide binding, phosphatase binding, protein binding, protein binding transcription factor activity, single-stranded DNA binding Human CRYAA HGNC UniProtKB {GO:0005515=PMID:14752512, GO:0042542=GO_REF:0000019, GO:0005212=GO_REF:0000037, GO:0030307=GO_REF:0000019, GO:0005634=PMID:19464326, GO:0046872=GO_REF:0000037, GO:0048596=GO_REF:0000019, GO:0042802=GO_REF:0000019, GO:0042026=GO_REF:0000024, GO:0005737=PMID:14752512, GO:0007015=GO_REF:0000019, GO:0070309=GO_REF:0000019, GO:0051260=PMID:16303126, GO:0043154=GO_REF:0000019, GO:0010288=GO_REF:0000019, GO:0001666=GO_REF:0000019, GO:0043066=PMID:14752512, GO:0032387=PMID:14752512, GO:0042493=GO_REF:0000019, GO:0051384=GO_REF:0000019, GO:0060561=GO_REF:0000019, GO:0070141=GO_REF:0000019, GO:0007021=GO_REF:0000019, GO:0010629=GO_REF:0000019, GO:0001934=GO_REF:0000019, GO:0007005=GO_REF:0000019, GO:0051082=PMID:8943244, GO:0000072=GO_REF:0000019, GO:0007601=PMID:9467006} P02489 Alpha-crystallin A chain protein 20070313 {GO:0005515=IPI, GO:0042542=IEA, GO:0005212=IEA, GO:0030307=IEA, GO:0005634=IDA, GO:0046872=IEA, GO:0048596=IEA, GO:0042802=IEA, GO:0042026=ISS, GO:0005737=IDA, GO:0007015=IEA, GO:0070309=IEA, GO:0051260=IDA, GO:0043154=IEA, GO:0010288=IEA, GO:0001666=IEA, GO:0043066=IDA, GO:0032387=IDA, GO:0042493=IEA, GO:0051384=IEA, GO:0060561=IEA, GO:0070141=IEA, GO:0007021=IEA, GO:0010629=IEA, GO:0001934=IEA, GO:0007005=IEA, GO:0051082=IPI, GO:0000072=IEA, GO:0007601=IMP} M phase specific microtubule process, actin filament organization, apoptotic process involved in morphogenesis, embryonic camera-type eye morphogenesis, lens fiber cell morphogenesis, mitochondrion organization, negative regulation of apoptotic process, negative regulation of cysteine-type endopeptidase activity involved in apoptotic process, negative regulation of gene expression, negative regulation of intracellular transport, positive regulation of cell growth, positive regulation of protein phosphorylation, protein homooligomerization, protein refolding, response to UV-A, response to drug, response to glucocorticoid stimulus, response to hydrogen peroxide, response to hypoxia, response to lead ion, tubulin complex assembly, visual perception cytoplasm, nucleus identical protein binding, metal ion binding, protein binding, structural constituent of eye lens, unfolded protein binding Human CRYAB LIFEdb UniProtKB {GO:0005515=PMID:16225851, GO:0008017=GO_REF:0000019, GO:0042542=GO_REF:0000019, GO:0005212=GO_REF:0000037, GO:0030018=GO_REF:0000019, GO:0030308=GO_REF:0000019, GO:0005886=GO_REF:0000019, GO:0005634=PMID:19464326, GO:0031109=GO_REF:0000019, GO:0032432=GO_REF:0000019, GO:0051403=GO_REF:0000019, GO:0042803=PMID:19646995, GO:0046872=GO_REF:0000037, GO:0005829=GO_REF:0000019, GO:0005739=GO_REF:0000019, GO:0005737=GO_REF:0000054, GO:0006936=PMID:9731540, GO:0002088=GO_REF:0000019, GO:0006457=GO_REF:0000019, GO:0015630=GO_REF:0000019, GO:0006006=GO_REF:0000019, GO:0051260=PMID:16303126, GO:0043154=GO_REF:0000019, GO:0032355=GO_REF:0000019, GO:0001666=GO_REF:0000019, GO:0043066=PMID:14752512, GO:0032387=PMID:14752512, GO:0005794=GO_REF:0000019, GO:0009986=GO_REF:0000019, GO:0007568=GO_REF:0000019, GO:0060561=GO_REF:0000019, GO:0007517=GO_REF:0000019, GO:0007021=GO_REF:0000019, GO:0010629=GO_REF:0000019, GO:0051082=PMID:16303126, GO:2000378=GO_REF:0000019} P02511 Alpha-crystallin B chain protein 20100607 {GO:0005515=IPI, GO:0008017=IEA, GO:0042542=IEA, GO:0005212=IEA, GO:0030018=IEA, GO:0030308=IEA, GO:0005886=IEA, GO:0005634=IDA, GO:0031109=IEA, GO:0032432=IEA, GO:0051403=IEA, GO:0042803=IPI, GO:0046872=IEA, GO:0005829=IEA, GO:0005739=IEA, GO:0005737=IDA, GO:0006936=TAS, GO:0002088=IEA, GO:0006457=IEA, GO:0015630=IEA, GO:0006006=IEA, GO:0051260=IDA, GO:0043154=IEA, GO:0032355=IEA, GO:0001666=IEA, GO:0043066=IDA, GO:0032387=IDA, GO:0005794=IEA, GO:0009986=IEA, GO:0007568=IEA, GO:0060561=IEA, GO:0007517=IEA, GO:0007021=IEA, GO:0010629=IEA, GO:0051082=IPI, GO:2000378=IEA} aging, apoptotic process involved in morphogenesis, glucose metabolic process, lens development in camera-type eye, microtubule polymerization or depolymerization, muscle contraction, muscle organ development, negative regulation of apoptotic process, negative regulation of cell growth, negative regulation of cysteine-type endopeptidase activity involved in apoptotic process, negative regulation of gene expression, negative regulation of intracellular transport, negative regulation of reactive oxygen species metabolic process, protein folding, protein homooligomerization, response to estradiol stimulus, response to hydrogen peroxide, response to hypoxia, stress-activated MAPK cascade, tubulin complex assembly Golgi apparatus, Z disc, actin filament bundle, cell surface, cytoplasm, cytosol, microtubule cytoskeleton, mitochondrion, nucleus, plasma membrane metal ion binding, microtubule binding, protein binding, protein homodimerization activity, structural constituent of eye lens, unfolded protein binding Human CRYBA1 UniProtKB UniProtKB {GO:0003674=GO_REF:0000015, GO:0005737=GO_REF:0000024, GO:0005212=GO_REF:0000037, GO:0002088=GO_REF:0000019, GO:0005634=GO_REF:0000024, GO:0007601=PMID:18587492, GO:0042803=GO_REF:0000019} P05813 Beta-crystallin A3 protein 20120713 {GO:0003674=ND, GO:0005737=ISS, GO:0005212=IEA, GO:0002088=IEA, GO:0005634=ISS, GO:0007601=IMP, GO:0042803=IEA} lens development in camera-type eye, visual perception cytoplasm, nucleus molecular_function, protein homodimerization activity, structural constituent of eye lens Human UniProtKB:P14881 CRYBA2 UniProtKB UniProtKB {GO:0008150=GO_REF:0000015, GO:0003674=GO_REF:0000015, GO:0005212=GO_REF:0000037, GO:0002088=GO_REF:0000019, GO:0005575=GO_REF:0000015, GO:0042803=GO_REF:0000019} P53672 Beta-crystallin A2 protein 20090204 {GO:0008150=ND, GO:0003674=ND, GO:0005212=IEA, GO:0002088=IEA, GO:0005575=ND, GO:0042803=IEA} biological_process, lens development in camera-type eye cellular_component molecular_function, protein homodimerization activity, structural constituent of eye lens Human CRYBA4 UniProtKB UniProtKB {GO:0003674=GO_REF:0000015, GO:0005212=GO_REF:0000019, GO:0043010=PMID:16960806, GO:0005575=GO_REF:0000015, GO:0007601=PMID:16960806} P53673 Beta-crystallin A4 protein 20120720 {GO:0003674=ND, GO:0005212=IEA, GO:0043010=IMP, GO:0005575=ND, GO:0007601=IMP} camera-type eye development, visual perception cellular_component molecular_function, structural constituent of eye lens Human CRYBB1 PINC UniProtKB {GO:0005212=GO_REF:0000019, GO:0007601=PMID:8626774} P53674 Beta-crystallin B1 protein 20030904 {GO:0005212=IEA, GO:0007601=TAS} visual perception structural constituent of eye lens Human CRYBB2 IntAct UniProtKB {GO:0005212=GO_REF:0000019, GO:0005198=PMID:8224918, GO:0043010=GO_REF:0000019, GO:0007601=GO_REF:0000019, GO:0042803=GO_REF:0000019, GO:0050896=GO_REF:0000037, GO:0042802=PMID:16319073} P43320 Beta-crystallin B2 protein 20130415 {GO:0005212=IEA, GO:0005198=NAS, GO:0043010=IEA, GO:0007601=IEA, GO:0042803=IEA, GO:0050896=IEA, GO:0042802=IPI} camera-type eye development, response to stimulus, visual perception identical protein binding, protein homodimerization activity, structural constituent of eye lens, structural molecule activity Human UniProtKB:P43320 CRYBB3 PINC UniProtKB {GO:0005212=GO_REF:0000019, GO:0007601=PMID:8999933} P26998 Beta-crystallin B3 protein 20030904 {GO:0005212=IEA, GO:0007601=TAS} visual perception structural constituent of eye lens Human CRYGC UniProtKB UniProtKB {GO:0005515=PMID:16303126, GO:0005212=PMID:12507494, GO:0005737=PMID:16303126, GO:0005634=PMID:16303126, GO:0043010=GO_REF:0000019, GO:0007601=PMID:18618005} P07315 Gamma-crystallin C protein 20090204 {GO:0005515=IPI, GO:0005212=NAS, GO:0005737=IDA, GO:0005634=IDA, GO:0043010=IEA, GO:0007601=IMP} camera-type eye development, visual perception cytoplasm, nucleus protein binding, structural constituent of eye lens Human CRYGD UniProtKB UniProtKB {GO:0005515=PMID:8943244, GO:0005737=GO_REF:0000024, GO:0005212=PMID:12507494, GO:0070306=GO_REF:0000024, GO:0002088=GO_REF:0000024, GO:0034614=PMID:8943244, GO:0005634=GO_REF:0000024, GO:0007601=PMID:9927684} P07320 Gamma-crystallin D protein 20120713 {GO:0005515=IPI, GO:0005737=ISS, GO:0005212=NAS, GO:0070306=ISS, GO:0002088=ISS, GO:0034614=IDA, GO:0005634=ISS, GO:0007601=IMP} cellular response to reactive oxygen species, lens development in camera-type eye, lens fiber cell differentiation, visual perception cytoplasm, nucleus protein binding, structural constituent of eye lens Human UniProtKB:P04342 CRYGS ENSEMBL UniProtKB {GO:0005212=GO_REF:0000019, GO:0002088=GO_REF:0000019, GO:0002009=GO_REF:0000019} P22914 Beta-crystallin S protein 20130413 {GO:0005212=IEA, GO:0002088=IEA, GO:0002009=IEA} lens development in camera-type eye, morphogenesis of an epithelium structural constituent of eye lens Human Ensembl:ENSMUSP00000043588 CRYL1 UniProtKB UniProtKB {GO:0050104=PMID:15809331, GO:0006631=GO_REF:0000002, GO:0070403=PMID:15809331, GO:0003857=GO_REF:0000002, GO:0042803=PMID:15809331, GO:0005829=GO_REF:0000024} Q9Y2S2 Lambda-crystallin homolog protein 20090720 {GO:0050104=IDA, GO:0006631=IEA, GO:0070403=IDA, GO:0003857=IEA, GO:0042803=IPI, GO:0005829=ISS} fatty acid metabolic process cytosol 3-hydroxyacyl-CoA dehydrogenase activity, L-gulonate 3-dehydrogenase activity, NAD+ binding, protein homodimerization activity Human CRYM HPA UniProtKB {GO:0050661=PMID:17242435, GO:0005886=GO_REF:0000052, GO:0007605=PMID:12471561, GO:0003714=PMID:11897713, GO:0042562=GO_REF:0000019, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0070327=PMID:11897713, GO:0000122=PMID:11897713, GO:0070324=PMID:9328354, GO:0042803=PMID:12590647, GO:0005739=GO_REF:0000019, GO:0047127=GO_REF:0000003, GO:0042403=GO_REF:0000019, GO:0005737=GO_REF:0000052} Q14894 Thiomorpholine-carboxylate dehydrogenase protein 20101115 {GO:0050661=IDA, GO:0005886=IDA, GO:0007605=IMP, GO:0003714=IMP, GO:0042562=IEA, GO:0005730=IDA, GO:0005634=IDA, GO:0070327=IMP, GO:0000122=IMP, GO:0070324=IDA, GO:0042803=IDA, GO:0005739=IEA, GO:0047127=IEA, GO:0042403=IEA, GO:0005737=IDA} negative regulation of transcription from RNA polymerase II promoter, sensory perception of sound, thyroid hormone metabolic process, thyroid hormone transport cytoplasm, mitochondrion, nucleolus, nucleus, plasma membrane NADP binding, hormone binding, protein homodimerization activity, thiomorpholine-carboxylate dehydrogenase activity, thyroid hormone binding, transcription corepressor activity Human CRYZ HPA UniProtKB {GO:0005794=GO_REF:0000052, GO:0042178=PMID:17497241, GO:0070404=PMID:17497241, GO:0003960=PMID:17497241, GO:0070402=PMID:17497241, GO:0043231=GO_REF:0000052, GO:0005829=PMID:17497241, GO:0005737=GO_REF:0000052, GO:0051289=PMID:17497241, GO:0016491=GO_REF:0000002, GO:0008270=GO_REF:0000002, GO:0003730=PMID:17497241, GO:0007601=PMID:7835889} Q08257 Quinone oxidoreductase protein 20100326 {GO:0005794=IDA, GO:0042178=IDA, GO:0070404=IDA, GO:0003960=IDA, GO:0070402=IDA, GO:0043231=IDA, GO:0005829=IDA, GO:0005737=IDA, GO:0051289=IPI, GO:0016491=IEA, GO:0008270=IEA, GO:0003730=IDA, GO:0007601=TAS} protein homotetramerization, visual perception, xenobiotic catabolic process Golgi apparatus, cytoplasm, cytosol, intracellular membrane-bounded organelle NADH binding, NADPH binding, NADPH:quinone reductase activity, mRNA 3'-UTR binding, oxidoreductase activity, zinc ion binding Human CRYZL1 UniProtKB UniProtKB {GO:0050661=PMID:10191096, GO:0016491=GO_REF:0000002, GO:0008270=GO_REF:0000002, GO:0003960=PMID:10191096, GO:0042375=PMID:10191096, GO:0005829=PMID:16780588} O95825 Quinone oxidoreductase-like protein 1 protein 20090218 {GO:0050661=NAS, GO:0016491=IEA, GO:0008270=IEA, GO:0003960=NAS, GO:0042375=NAS, GO:0005829=IDA} quinone cofactor metabolic process cytosol NADP binding, NADPH:quinone reductase activity, oxidoreductase activity, zinc ion binding Human CS HPA UniProtKB {GO:0005739=GO_REF:0000052, GO:0044262=GO_REF:0000002, GO:0006099=Reactome:REACT_1785, GO:0005975=PMID:9543345, GO:0005759=Reactome:REACT_1282, GO:0046912=GO_REF:0000002, GO:0004108=Reactome:REACT_1282, GO:0044281=Reactome:REACT_111217} O75390 Citrate synthase, mitochondrial protein 20110516 {GO:0005739=IDA, GO:0044262=IEA, GO:0006099=TAS, GO:0005975=IDA, GO:0005759=TAS, GO:0046912=IEA, GO:0004108=TAS, GO:0044281=TAS} carbohydrate metabolic process, cellular carbohydrate metabolic process, small molecule metabolic process, tricarboxylic acid cycle mitochondrial matrix, mitochondrion citrate (Si)-synthase activity, transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer Human CSAD InterPro UniProtKB {GO:0034641=Reactome:REACT_13, GO:0000096=Reactome:REACT_115639, GO:0000098=Reactome:REACT_115654, GO:0030170=GO_REF:0000002, GO:0016831=GO_REF:0000002, GO:0004782=GO_REF:0000003, GO:0044281=Reactome:REACT_111217, GO:0042412=GO_REF:0000041, GO:0019752=GO_REF:0000002} Q9Y602 Cysteine sulfinic acid decarboxylase, isoform CRA_c protein 20130413 {GO:0034641=TAS, GO:0000096=TAS, GO:0000098=TAS, GO:0030170=IEA, GO:0016831=IEA, GO:0004782=IEA, GO:0044281=TAS, GO:0042412=IEA, GO:0019752=IEA} carboxylic acid metabolic process, cellular nitrogen compound metabolic process, small molecule metabolic process, sulfur amino acid catabolic process, sulfur amino acid metabolic process, taurine biosynthetic process carboxy-lyase activity, pyridoxal phosphate binding, sulfinoalanine decarboxylase activity Human InterPro:IPR002129|InterPro:IPR015421 CSAG1 null null {} null null null null {} null null null CSDC2 UniProtKB UniProtKB {GO:0005737=GO_REF:0000029, GO:0006355=GO_REF:0000002, GO:0006398=GO_REF:0000029, GO:0003723=PMID:12801884, GO:0005634=GO_REF:0000029, GO:0003677=GO_REF:0000002} Q9Y534 Cold shock domain-containing protein C2 protein 20040206 {GO:0005737=NAS, GO:0006355=IEA, GO:0006398=NAS, GO:0003723=NAS, GO:0005634=NAS, GO:0003677=IEA} histone mRNA 3'-end processing, regulation of transcription, DNA-dependent cytoplasm, nucleus DNA binding, RNA binding Human CSDE1 PINC UniProtKB {GO:0006355=GO_REF:0000002, GO:0003723=GO_REF:0000037, GO:0005743=GO_REF:0000019, GO:0070966=PMID:15314026, GO:0003677=GO_REF:0000002, GO:0008584=PMID:2204029, GO:0070937=PMID:15314026} O75534 Cold shock domain-containing protein E1 protein 20030904 {GO:0006355=IEA, GO:0003723=IEA, GO:0005743=IEA, GO:0070966=IMP, GO:0003677=IEA, GO:0008584=TAS, GO:0070937=IDA} male gonad development, nuclear-transcribed mRNA catabolic process, no-go decay, regulation of transcription, DNA-dependent CRD-mediated mRNA stability complex, mitochondrial inner membrane DNA binding, RNA binding Human CSE1L IntAct UniProtKB {GO:0005515=PMID:17719542, GO:0005737=GO_REF:0000039, GO:0008283=PMID:7479798, GO:0005643=GO_REF:0000002, GO:0008565=GO_REF:0000002, GO:0006915=PMID:7479798, GO:0005634=PMID:9323134, GO:0008262=PMID:9323134, GO:0006886=GO_REF:0000002} P55060 Exportin-2 protein 20130415 {GO:0005515=IPI, GO:0005737=IEA, GO:0008283=TAS, GO:0005643=IEA, GO:0008565=IEA, GO:0006915=TAS, GO:0005634=TAS, GO:0008262=TAS, GO:0006886=IEA} apoptotic process, cell proliferation, intracellular protein transport cytoplasm, nuclear pore, nucleus importin-alpha export receptor activity, protein binding, protein transporter activity Human UniProtKB:P04637 CSF1 BHF-UCL UniProtKB {GO:0048471=PMID:1739124, GO:0008284=PMID:10652277, GO:0005886=GO_REF:0000039, GO:0008283=PMID:1791839, GO:0005157=PMID:19017797, GO:0046579=GO_REF:0000019, GO:0005615=PMID:2460758, GO:0030154=PMID:1791839, GO:0042803=PMID:3264878, GO:0006954=GO_REF:0000037, GO:0030278=GO_REF:0000019, GO:0048873=GO_REF:0000019, GO:0045657=PMID:18566389, GO:0045860=PMID:18566389, GO:0042476=GO_REF:0000019, GO:0030225=PMID:2460758, GO:0040018=GO_REF:0000019, GO:0030097=PMID:1791839, GO:0030335=PMID:18566389, GO:0010744=PMID:17244792, GO:0010743=PMID:18566389, GO:0030316=PMID:18606301, GO:0045672=PMID:15304486, GO:0060763=GO_REF:0000019, GO:0045651=PMID:2460758, GO:0005125=PMID:2460758, GO:0010628=PMID:1739124, GO:0043235=PMID:19017797, GO:0032270=PMID:1739124, GO:0003006=PMID:19017797, GO:0032946=PMID:2460758, GO:0016020=PMID:2460758, GO:0001503=GO_REF:0000019, GO:0042117=PMID:18566389, GO:0045087=GO_REF:0000037, GO:0016021=GO_REF:0000037, GO:0060611=GO_REF:0000019, GO:0008083=PMID:2460758, GO:0042488=GO_REF:0000019, GO:0001954=PMID:18566389, GO:0060444=GO_REF:0000019} P09603 Macrophage colony-stimulating factor 1 protein 20090115 {GO:0048471=IDA, GO:0008284=IDA, GO:0005886=IEA, GO:0008283=NAS, GO:0005157=ISS, GO:0046579=IEA, GO:0005615=IDA, GO:0030154=NAS, GO:0042803=IDA, GO:0006954=IEA, GO:0030278=IEA, GO:0048873=IEA, GO:0045657=ISS, GO:0045860=ISS, GO:0042476=IEA, GO:0030225=TAS, GO:0040018=IEA, GO:0030097=NAS, GO:0030335=ISS, GO:0010744=IDA, GO:0010743=NAS, GO:0030316=IDA, GO:0045672=IDA, GO:0060763=IEA, GO:0045651=IDA, GO:0005125=IDA, GO:0010628=IDA, GO:0043235=ISS, GO:0032270=IDA, GO:0003006=ISS, GO:0032946=IDA, GO:0016020=NAS, GO:0001503=IEA, GO:0042117=NAS, GO:0045087=IEA, GO:0016021=IEA, GO:0060611=IEA, GO:0008083=IDA, GO:0042488=IEA, GO:0001954=ISS, GO:0060444=IEA} branching involved in mammary gland duct morphogenesis, cell differentiation, cell proliferation, developmental process involved in reproduction, hemopoiesis, homeostasis of number of cells within a tissue, inflammatory response, innate immune response, macrophage differentiation, mammary duct terminal end bud growth, mammary gland fat development, monocyte activation, odontogenesis, ossification, osteoclast differentiation, positive regulation of Ras protein signal transduction, positive regulation of cell migration, positive regulation of cell proliferation, positive regulation of cell-matrix adhesion, positive regulation of cellular protein metabolic process, positive regulation of gene expression, positive regulation of macrophage derived foam cell differentiation, positive regulation of macrophage differentiation, positive regulation of monocyte differentiation, positive regulation of mononuclear cell proliferation, positive regulation of multicellular organism growth, positive regulation of odontogenesis of dentin-containing tooth, positive regulation of osteoclast differentiation, positive regulation of protein kinase activity, regulation of macrophage derived foam cell differentiation, regulation of ossification extracellular space, integral to membrane, membrane, perinuclear region of cytoplasm, plasma membrane, receptor complex cytokine activity, growth factor activity, macrophage colony-stimulating factor receptor binding, protein homodimerization activity Human UniProtKB:P07141 CSF1R GOC UniProtKB {GO:0008284=PMID:15117969, GO:0005886=PMID:2421165, GO:0071902=GO_REF:0000024, GO:0008283=PMID:7683918, GO:0061098=PMID:7681396, GO:0008360=PMID:15117969, GO:0019221=PMID:20504948, GO:0045124=GO_REF:0000024, GO:2000147=PMID:15117969, GO:0042803=PMID:19017797, GO:0031529=GO_REF:0000024, GO:2000249=GO_REF:0000024, GO:0006954=PMID:19132917, GO:0046777=PMID:20504948, GO:0030225=PMID:19132917, GO:0030224=PMID:19132917, GO:0070374=GO_REF:0000024, GO:0060603=PMID:15117969, GO:0090197=PMID:20829061, GO:0038145=PMID:8981357, GO:0030097=PMID:7683918, GO:0036006=PMID:20504948, GO:0030335=GO_REF:0000024, GO:0009986=GO_REF:0000024, GO:0042517=GO_REF:0000024, GO:0048015=GO_REF:0000024, GO:0046488=GO_REF:0000024, GO:0030316=GO_REF:0000024, GO:0007275=PMID:8981357, GO:0018108=PMID:20504948, GO:0005524=GO_REF:0000037, GO:0045217=PMID:15117969, GO:0043235=PMID:19017797, GO:0007165=PMID:8981357, GO:0019955=PMID:19017797, GO:0016020=GO_REF:0000002, GO:0005887=PMID:2421165, GO:0071345=GO_REF:0000024, GO:0045087=GO_REF:0000037, GO:0001934=PMID:20504948, GO:0005011=PMID:20504948, GO:0004714=GO_REF:0000002, GO:0007169=GO_REF:0000024} P07333 Macrophage colony-stimulating factor 1 receptor protein 20130413 {GO:0008284=IMP, GO:0005886=TAS, GO:0071902=ISS, GO:0008283=IMP, GO:0061098=IMP, GO:0008360=IMP, GO:0019221=IMP, GO:0045124=ISS, GO:2000147=IMP, GO:0042803=ISS, GO:0031529=ISS, GO:2000249=ISS, GO:0006954=TAS, GO:0046777=IDA, GO:0030225=TAS, GO:0030224=TAS, GO:0070374=ISS, GO:0060603=TAS, GO:0090197=IMP, GO:0038145=TAS, GO:0030097=IMP, GO:0036006=IMP, GO:0030335=ISS, GO:0009986=ISS, GO:0042517=ISS, GO:0048015=ISS, GO:0046488=ISS, GO:0030316=ISS, GO:0007275=TAS, GO:0018108=IDA, GO:0005524=IEA, GO:0045217=IMP, GO:0043235=ISS, GO:0007165=TAS, GO:0019955=ISS, GO:0016020=IEA, GO:0005887=TAS, GO:0071345=ISS, GO:0045087=IEA, GO:0001934=IMP, GO:0005011=IMP, GO:0004714=IEA, GO:0007169=ISS} cell proliferation, cell-cell junction maintenance, cellular response to cytokine stimulus, cellular response to macrophage colony-stimulating factor stimulus, cytokine-mediated signaling pathway, hemopoiesis, inflammatory response, innate immune response, macrophage colony-stimulating factor signaling pathway, macrophage differentiation, mammary gland duct morphogenesis, monocyte differentiation, multicellular organismal development, osteoclast differentiation, peptidyl-tyrosine phosphorylation, phosphatidylinositol metabolic process, phosphatidylinositol-mediated signaling, positive regulation of ERK1 and ERK2 cascade, positive regulation of cell migration, positive regulation of cell motility, positive regulation of cell proliferation, positive regulation of chemokine secretion, positive regulation of protein phosphorylation, positive regulation of protein serine/threonine kinase activity, positive regulation of protein tyrosine kinase activity, positive regulation of tyrosine phosphorylation of Stat3 protein, protein autophosphorylation, regulation of actin cytoskeleton reorganization, regulation of bone resorption, regulation of cell shape, ruffle organization, signal transduction, transmembrane receptor protein tyrosine kinase signaling pathway cell surface, integral to plasma membrane, membrane, plasma membrane, receptor complex ATP binding, cytokine binding, macrophage colony-stimulating factor receptor activity, protein homodimerization activity, transmembrane receptor protein tyrosine kinase activity Human CSF2 BHF-UCL UniProtKB {GO:0005515=PMID:18692472, GO:0071803=PMID:15220135, GO:0043066=PMID:10666185, GO:0008284=GO_REF:0000019, GO:0010744=PMID:19032770, GO:0045740=PMID:9722506, GO:0032747=PMID:20027291, GO:0042523=PMID:9722506, GO:0001892=GO_REF:0000019, GO:0005576=Reactome:REACT_24024, GO:0097028=PMID:21149635, GO:0005125=GO_REF:0000019, GO:0005615=GO_REF:0000019, GO:0010628=PMID:10666185, GO:0042045=GO_REF:0000019, GO:0006955=GO_REF:0000002, GO:0071222=GO_REF:0000019, GO:0042116=GO_REF:0000019, GO:0045918=PMID:10666185, GO:0043011=GO_REF:0000019, GO:0008083=GO_REF:0000037, GO:0005129=GO_REF:0000002} P04141 Granulocyte-macrophage colony-stimulating factor protein 20110220 {GO:0005515=IPI, GO:0071803=IDA, GO:0043066=IDA, GO:0008284=IEA, GO:0010744=IDA, GO:0045740=IDA, GO:0032747=IDA, GO:0042523=IDA, GO:0001892=IEA, GO:0005576=TAS, GO:0097028=IDA, GO:0005125=IEA, GO:0005615=IEA, GO:0010628=IDA, GO:0042045=IEA, GO:0006955=IEA, GO:0071222=IEA, GO:0042116=IEA, GO:0045918=IDA, GO:0043011=IEA, GO:0008083=IEA, GO:0005129=IEA} cellular response to lipopolysaccharide, dendritic cell differentiation, embryonic placenta development, epithelial fluid transport, immune response, macrophage activation, myeloid dendritic cell differentiation, negative regulation of apoptotic process, negative regulation of cytolysis, positive regulation of DNA replication, positive regulation of cell proliferation, positive regulation of gene expression, positive regulation of interleukin-23 production, positive regulation of macrophage derived foam cell differentiation, positive regulation of podosome assembly, positive regulation of tyrosine phosphorylation of Stat5 protein extracellular region, extracellular space cytokine activity, granulocyte macrophage colony-stimulating factor receptor binding, growth factor activity, protein binding Human CSF2RA Reactome UniProtKB {GO:0004896=GO_REF:0000002, GO:0005886=Reactome:REACT_24024, GO:0016020=GO_REF:0000002, GO:0005887=PMID:2555171, GO:0004872=PMID:1358805, GO:0005576=GO_REF:0000039} P15509 Granulocyte-macrophage colony-stimulating factor receptor subunit alpha protein 20100714 {GO:0004896=IEA, GO:0005886=TAS, GO:0016020=IEA, GO:0005887=TAS, GO:0004872=TAS, GO:0005576=IEA} extracellular region, integral to plasma membrane, membrane, plasma membrane cytokine receptor activity, receptor activity Human CSF2RB GOC UniProtKB {GO:0005515=PMID:20802515, GO:0038156=PMID:9410898, GO:0004896=GO_REF:0000002, GO:0007585=PMID:9410898, GO:0005886=Reactome:REACT_24024, GO:0004912=PMID:9410898, GO:0038043=PMID:9410898, GO:0004914=PMID:9410898, GO:0036016=PMID:9410898, GO:0007165=PMID:1702217, GO:0030526=PMID:9410898, GO:0016020=GO_REF:0000002, GO:0005887=PMID:1702217, GO:0004872=PMID:9410898} P32927 Cytokine receptor common subunit beta protein 20130413 {GO:0005515=IPI, GO:0038156=TAS, GO:0004896=IEA, GO:0007585=TAS, GO:0005886=TAS, GO:0004912=TAS, GO:0038043=TAS, GO:0004914=TAS, GO:0036016=TAS, GO:0007165=NAS, GO:0030526=TAS, GO:0016020=IEA, GO:0005887=NAS, GO:0004872=TAS} cellular response to interleukin-3, interleukin-3-mediated signaling pathway, interleukin-5-mediated signaling pathway, respiratory gaseous exchange, signal transduction granulocyte macrophage colony-stimulating factor receptor complex, integral to plasma membrane, membrane, plasma membrane cytokine receptor activity, interleukin-3 receptor activity, interleukin-5 receptor activity, protein binding, receptor activity Human CSF3 InterPro UniProtKB {GO:0051897=PMID:23001182, GO:0008284=GO_REF:0000019, GO:0019221=PMID:15664994, GO:0005130=PMID:2420009, GO:0050731=PMID:23001182, GO:2000251=PMID:23001182, GO:1901215=GO_REF:0000019, GO:0014068=PMID:23001182, GO:0005576=GO_REF:0000002, GO:0007275=PMID:2420009, GO:0042993=PMID:23001182, GO:0005125=GO_REF:0000002, GO:0005615=GO_REF:0000019, GO:0032092=PMID:23001182, GO:0033138=PMID:23001182, GO:0006955=GO_REF:0000002, GO:0071222=GO_REF:0000019, GO:0030838=PMID:23001182, GO:0071345=PMID:23001182, GO:0045944=PMID:23001182, GO:0030851=PMID:15664994, GO:0019899=PMID:12393522, GO:0008083=GO_REF:0000019} Q8N4W3 Colony stimulating factor 3 (Granulocyte) protein 20130413 {GO:0051897=IDA, GO:0008284=IEA, GO:0019221=NAS, GO:0005130=TAS, GO:0050731=IDA, GO:2000251=IDA, GO:1901215=IEA, GO:0014068=IDA, GO:0005576=IEA, GO:0007275=TAS, GO:0042993=IDA, GO:0005125=IEA, GO:0005615=IEA, GO:0032092=IDA, GO:0033138=IDA, GO:0006955=IEA, GO:0071222=IEA, GO:0030838=IDA, GO:0071345=IDA, GO:0045944=IDA, GO:0030851=NAS, GO:0019899=IPI, GO:0008083=IEA} cellular response to cytokine stimulus, cellular response to lipopolysaccharide, cytokine-mediated signaling pathway, granulocyte differentiation, immune response, multicellular organismal development, negative regulation of neuron death, positive regulation of actin cytoskeleton reorganization, positive regulation of actin filament polymerization, positive regulation of cell proliferation, positive regulation of peptidyl-serine phosphorylation, positive regulation of peptidyl-tyrosine phosphorylation, positive regulation of phosphatidylinositol 3-kinase cascade, positive regulation of protein binding, positive regulation of protein kinase B signaling cascade, positive regulation of transcription factor import into nucleus, positive regulation of transcription from RNA polymerase II promoter extracellular region, extracellular space cytokine activity, enzyme binding, granulocyte colony-stimulating factor receptor binding, growth factor activity Human InterPro:IPR003573 CSF3R PINC UniProtKB {GO:0007165=PMID:1371413, GO:0004896=GO_REF:0000002, GO:0016020=GO_REF:0000002, GO:0005887=PMID:7542747, GO:0030593=GO_REF:0000019, GO:0042475=GO_REF:0000019, GO:0006952=PMID:7542747, GO:0004872=PMID:7542747, GO:0005576=GO_REF:0000039, GO:0007155=GO_REF:0000037} Q99062 Granulocyte colony-stimulating factor receptor protein 20040811 {GO:0007165=NAS, GO:0004896=IEA, GO:0016020=IEA, GO:0005887=TAS, GO:0030593=IEA, GO:0042475=IEA, GO:0006952=TAS, GO:0004872=TAS, GO:0005576=IEA, GO:0007155=IEA} cell adhesion, defense response, neutrophil chemotaxis, odontogenesis of dentin-containing tooth, signal transduction extracellular region, integral to plasma membrane, membrane cytokine receptor activity, receptor activity Human CSGALNACT1 Reactome UniProtKB {GO:0008037=PMID:11514575, GO:0051216=GO_REF:0000019, GO:0008283=PMID:11514575, GO:0044281=Reactome:REACT_111217, GO:0009653=PMID:11514575, GO:0015014=PMID:11514575, GO:0046872=PMID:12163485, GO:0005622=PMID:12163485, GO:0030206=Reactome:REACT_120989, GO:0030198=PMID:11514575, GO:0032580=GO_REF:0000039, GO:0030204=Reactome:REACT_121206, GO:0030203=Reactome:REACT_121315, GO:0047238=PMID:12163485, GO:0047237=PMID:12163485, GO:0050653=PMID:12163485, GO:0008955=PMID:11514575, GO:0050650=PMID:11788602, GO:0050651=PMID:11788602, GO:0016758=GO_REF:0000002, GO:0005975=Reactome:REACT_474, GO:0019276=PMID:11514575, GO:0015020=PMID:11514575, GO:0008376=PMID:11514575, GO:0007399=PMID:11514575, GO:0030166=PMID:11788602, GO:0030173=PMID:11514575, GO:0001958=GO_REF:0000019, GO:0000139=Reactome:REACT_120769, GO:0046398=PMID:11514575, GO:0030210=PMID:11514575} Q8TDX6 Chondroitin sulfate N-acetylgalactosaminyltransferase 1 protein 20130301 {GO:0008037=NAS, GO:0051216=IEA, GO:0008283=NAS, GO:0044281=TAS, GO:0009653=NAS, GO:0015014=NAS, GO:0046872=NAS, GO:0005622=IC, GO:0030206=TAS, GO:0030198=NAS, GO:0032580=IEA, GO:0030204=TAS, GO:0030203=TAS, GO:0047238=IDA, GO:0047237=IDA, GO:0050653=IDA, GO:0008955=IDA, GO:0050650=ISS, GO:0050651=ISS, GO:0016758=IEA, GO:0005975=TAS, GO:0019276=IDA, GO:0015020=IDA, GO:0008376=IDA, GO:0007399=NAS, GO:0030166=ISS, GO:0030173=NAS, GO:0001958=IEA, GO:0000139=TAS, GO:0046398=IDA, GO:0030210=NAS} UDP-N-acetylgalactosamine metabolic process, UDP-glucuronate metabolic process, anatomical structure morphogenesis, carbohydrate metabolic process, cartilage development, cell proliferation, cell recognition, chondroitin sulfate biosynthetic process, chondroitin sulfate metabolic process, chondroitin sulfate proteoglycan biosynthetic process, chondroitin sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process, dermatan sulfate proteoglycan biosynthetic process, endochondral ossification, extracellular matrix organization, glycosaminoglycan metabolic process, heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process, heparin biosynthetic process, nervous system development, proteoglycan biosynthetic process, small molecule metabolic process Golgi cisterna membrane, Golgi membrane, integral to Golgi membrane, intracellular acetylgalactosaminyltransferase activity, glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity, glucuronosyltransferase activity, glucuronylgalactosylproteoglycan 4-beta-N-acetylgalactosaminyltransferase activity, metal ion binding, peptidoglycan glycosyltransferase activity, transferase activity, transferring hexosyl groups Human CSH1 Reactome UniProtKB {GO:0007165=PMID:593368, GO:0007565=PMID:1378436, GO:0005179=GO_REF:0000037, GO:0005576=Reactome:REACT_116060, GO:0060397=Reactome:REACT_111133, GO:0046872=GO_REF:0000037} P01243 Chorionic somatomammotropin hormone protein 20130301 {GO:0007165=NAS, GO:0007565=TAS, GO:0005179=IEA, GO:0005576=TAS, GO:0060397=TAS, GO:0046872=IEA} JAK-STAT cascade involved in growth hormone signaling pathway, female pregnancy, signal transduction extracellular region hormone activity, metal ion binding Human CSH2 UniProtKB UniProtKB {GO:0005179=GO_REF:0000038, GO:0005576=GO_REF:0000040} H0YN17 Chorionic somatomammotropin hormone protein 20130413 {GO:0005179=IEA, GO:0005576=IEA} extracellular region hormone activity Human UniProtKB-SubCell:SL-0243 CSHL1 UniProtKB UniProtKB {GO:0008150=GO_REF:0000015, GO:0005179=PMID:2744760, GO:0005576=GO_REF:0000039, GO:0005575=GO_REF:0000015, GO:0046872=GO_REF:0000037} Q14406 Chorionic somatomammotropin hormone-like 1 protein 20061026 {GO:0008150=ND, GO:0005179=NAS, GO:0005576=IEA, GO:0005575=ND, GO:0046872=IEA} biological_process cellular_component, extracellular region hormone activity, metal ion binding Human CSK HPA UniProtKB {GO:0005515=PMID:18614016, GO:0050852=Reactome:REACT_12526, GO:0008285=GO_REF:0000019, GO:0005886=Reactome:REACT_12601, GO:0032715=GO_REF:0000019, GO:0048709=GO_REF:0000019, GO:0031295=Reactome:REACT_19344, GO:0045779=GO_REF:0000019, GO:0043231=GO_REF:0000052, GO:0005829=Reactome:REACT_23821, GO:0050765=GO_REF:0000019, GO:0005737=GO_REF:0000052, GO:0046777=GO_REF:0000019, GO:0007173=Reactome:REACT_9417, GO:0005911=GO_REF:0000019, GO:0043406=GO_REF:0000019, GO:0071375=GO_REF:0000019, GO:0070373=GO_REF:0000019, GO:0010989=GO_REF:0000019, GO:0070064=GO_REF:0000019, GO:0033673=GO_REF:0000019, GO:0005813=GO_REF:0000052, GO:0005794=GO_REF:0000052, GO:0019903=GO_REF:0000019, GO:0030168=Reactome:REACT_798, GO:0008022=PMID:8890164, GO:0005524=GO_REF:0000037, GO:0007596=Reactome:REACT_604, GO:0007420=GO_REF:0000019, GO:0045121=GO_REF:0000019, GO:0006468=PMID:1945408, GO:0004713=Reactome:REACT_12640, GO:0004715=GO_REF:0000003, GO:0060368=GO_REF:0000019, GO:0034332=GO_REF:0000019} P41240 Tyrosine-protein kinase CSK protein 20101115 {GO:0005515=IPI, GO:0050852=TAS, GO:0008285=IEA, GO:0005886=TAS, GO:0032715=IEA, GO:0048709=IEA, GO:0031295=TAS, GO:0045779=IEA, GO:0043231=IDA, GO:0005829=TAS, GO:0050765=IEA, GO:0005737=IDA, GO:0046777=IEA, GO:0007173=TAS, GO:0005911=IEA, GO:0043406=IEA, GO:0071375=IEA, GO:0070373=IEA, GO:0010989=IEA, GO:0070064=IEA, GO:0033673=IEA, GO:0005813=IDA, GO:0005794=IDA, GO:0019903=IEA, GO:0030168=TAS, GO:0008022=TAS, GO:0005524=IEA, GO:0007596=TAS, GO:0007420=IEA, GO:0045121=IEA, GO:0006468=TAS, GO:0004713=TAS, GO:0004715=IEA, GO:0060368=IEA, GO:0034332=IEA} T cell costimulation, T cell receptor signaling pathway, adherens junction organization, blood coagulation, brain development, cellular response to peptide hormone stimulus, epidermal growth factor receptor signaling pathway, negative regulation of ERK1 and ERK2 cascade, negative regulation of bone resorption, negative regulation of cell proliferation, negative regulation of interleukin-6 production, negative regulation of kinase activity, negative regulation of low-density lipoprotein particle clearance, negative regulation of phagocytosis, oligodendrocyte differentiation, platelet activation, positive regulation of MAP kinase activity, protein autophosphorylation, protein phosphorylation, regulation of Fc receptor mediated stimulatory signaling pathway Golgi apparatus, cell-cell junction, centrosome, cytoplasm, cytosol, intracellular membrane-bounded organelle, membrane raft, plasma membrane ATP binding, non-membrane spanning protein tyrosine kinase activity, proline-rich region binding, protein C-terminus binding, protein binding, protein phosphatase binding, protein tyrosine kinase activity Human CSMD1 UniProtKB UniProtKB {GO:0016021=GO_REF:0000037} Q96PZ7 CUB and sushi domain-containing protein 1 protein 20130413 {GO:0016021=IEA} integral to membrane Human UniProtKB-KW:KW-0812 CSMD2 UniProtKB UniProtKB {GO:0005886=GO_REF:0000039, GO:0016021=GO_REF:0000037} Q7Z408 CUB and sushi domain-containing protein 2 protein 20130413 {GO:0005886=IEA, GO:0016021=IEA} integral to membrane, plasma membrane Human UniProtKB-SubCell:SL-0039 CSMD3 UniProtKB UniProtKB {GO:0005886=GO_REF:0000039, GO:0016021=GO_REF:0000037} Q7Z407 CUB and sushi domain-containing protein 3 protein 20130413 {GO:0005886=IEA, GO:0016021=IEA} integral to membrane, plasma membrane Human UniProtKB-SubCell:SL-0039 CSN1S1 UniProtKB UniProtKB {GO:0005215=GO_REF:0000002, GO:0005576=GO_REF:0000039} P47710 Alpha-S1-casein protein 20130413 {GO:0005215=IEA, GO:0005576=IEA} extracellular region transporter activity Human UniProtKB-SubCell:SL-0243 CSN2 GOC UniProtKB {GO:0004857=PMID:2387396, GO:0005215=GO_REF:0000002, GO:0005509=PMID:2387396, GO:0005576=Reactome:REACT_116088, GO:0006816=PMID:2387396, GO:0043086=PMID:2387396} P05814 Beta-casein protein 20130413 {GO:0004857=TAS, GO:0005215=IEA, GO:0005509=TAS, GO:0005576=TAS, GO:0006816=TAS, GO:0043086=TAS} calcium ion transport, negative regulation of catalytic activity extracellular region calcium ion binding, enzyme inhibitor activity, transporter activity Human CSN3 UniProtKB UniProtKB {GO:0007595=GO_REF:0000019, GO:0005576=GO_REF:0000029} P07498 Kappa-casein protein 20021104 {GO:0007595=IEA, GO:0005576=NAS} lactation extracellular region Human CSNK1A1 UniProtKB UniProtKB {GO:0005515=PMID:20708156, GO:0005813=PMID:21399614, GO:0005524=GO_REF:0000038, GO:0005829=Reactome:REACT_10134, GO:0007165=PMID:10777483, GO:0007067=GO_REF:0000037, GO:0004672=PMID:10777483, GO:0016607=PMID:18305108, GO:0004674=GO_REF:0000038, GO:0000777=GO_REF:0000039, GO:0005847=PMID:18305108, GO:0006468=PMID:18305108, GO:0016055=GO_REF:0000037, GO:0007166=PMID:10777483, GO:0051301=GO_REF:0000037} Q71TU5 Casein kinase I isoform alpha protein 20130413 {GO:0005515=IPI, GO:0005813=IDA, GO:0005524=IEA, GO:0005829=TAS, GO:0007165=NAS, GO:0007067=IEA, GO:0004672=TAS, GO:0016607=IDA, GO:0004674=IEA, GO:0000777=IEA, GO:0005847=IDA, GO:0006468=IDA, GO:0016055=IEA, GO:0007166=TAS, GO:0051301=IEA} Wnt receptor signaling pathway, cell division, cell surface receptor signaling pathway, mitosis, protein phosphorylation, signal transduction centrosome, condensed chromosome kinetochore, cytosol, mRNA cleavage and polyadenylation specificity factor complex, nuclear speck ATP binding, protein binding, protein kinase activity, protein serine/threonine kinase activity Human UniProtKB-KW:KW-0067 CSNK1A1L UniProtKB UniProtKB {GO:0000902=GO_REF:0000019, GO:0005737=GO_REF:0000039, GO:0004674=GO_REF:0000037, GO:0030529=GO_REF:0000019, GO:0016055=GO_REF:0000037, GO:0005524=GO_REF:0000037} Q8N752 Casein kinase I isoform alpha-like protein 20130413 {GO:0000902=IEA, GO:0005737=IEA, GO:0004674=IEA, GO:0030529=IEA, GO:0016055=IEA, GO:0005524=IEA} Wnt receptor signaling pathway, cell morphogenesis cytoplasm, ribonucleoprotein complex ATP binding, protein serine/threonine kinase activity Human UniProtKB-SubCell:SL-0086 CSNK1D BHF-UCL UniProtKB {GO:0005515=PMID:16618118, GO:0048471=PMID:16027726, GO:0005886=PMID:16027726, GO:0090263=PMID:20412773, GO:0032436=GO_REF:0000024, GO:0050321=GO_REF:0000003, GO:0005634=GO_REF:0000024, GO:0005829=Reactome:REACT_15470, GO:0000086=Reactome:REACT_2203, GO:0005876=PMID:10826492, GO:0016055=GO_REF:0000037, GO:0005813=PMID:21399614, GO:0005794=PMID:10826492, GO:0005819=PMID:10826492, GO:0051225=PMID:10826492, GO:0005524=GO_REF:0000037, GO:0032922=GO_REF:0000024, GO:0007165=PMID:8786104, GO:0004672=PMID:16618118, GO:0006281=PMID:8786104, GO:0004674=GO_REF:0000037, GO:0001934=PMID:20412773, GO:0042752=GO_REF:0000024, GO:0006468=PMID:16618118, GO:0000278=Reactome:REACT_152} P48730 Casein kinase I isoform delta protein 20100721 {GO:0005515=IPI, GO:0048471=IDA, GO:0005886=IDA, GO:0090263=IMP, GO:0032436=ISS, GO:0050321=IEA, GO:0005634=ISS, GO:0005829=TAS, GO:0000086=TAS, GO:0005876=IDA, GO:0016055=IEA, GO:0005813=IDA, GO:0005794=IDA, GO:0005819=IDA, GO:0051225=IDA, GO:0005524=IEA, GO:0032922=ISS, GO:0007165=TAS, GO:0004672=IDA, GO:0006281=TAS, GO:0004674=IEA, GO:0001934=IMP, GO:0042752=ISS, GO:0006468=IDA, GO:0000278=TAS} DNA repair, G2/M transition of mitotic cell cycle, Wnt receptor signaling pathway, circadian regulation of gene expression, mitotic cell cycle, positive regulation of canonical Wnt receptor signaling pathway, positive regulation of proteasomal ubiquitin-dependent protein catabolic process, positive regulation of protein phosphorylation, protein phosphorylation, regulation of circadian rhythm, signal transduction, spindle assembly Golgi apparatus, centrosome, cytosol, nucleus, perinuclear region of cytoplasm, plasma membrane, spindle, spindle microtubule ATP binding, protein binding, protein kinase activity, protein serine/threonine kinase activity, tau-protein kinase activity Human CSNK1E IntAct UniProtKB {GO:0005515=PMID:22939624, GO:0090263=GO_REF:0000019, GO:0030178=GO_REF:0000019, GO:0032436=GO_REF:0000024, GO:0005634=GO_REF:0000024, GO:0005524=GO_REF:0000037, GO:0005829=Reactome:REACT_15470, GO:0007165=PMID:7797465, GO:0005737=GO_REF:0000019, GO:0006281=PMID:7797465, GO:0004672=GO_REF:0000024, GO:0004674=PMID:7797465, GO:0000086=Reactome:REACT_2203, GO:0030529=GO_REF:0000019, GO:0006468=GO_REF:0000024, GO:0034613=GO_REF:0000019, GO:0000278=Reactome:REACT_152} P49674 Casein kinase I isoform epsilon protein 20130415 {GO:0005515=IPI, GO:0090263=IEA, GO:0030178=IEA, GO:0032436=ISS, GO:0005634=ISS, GO:0005524=IEA, GO:0005829=TAS, GO:0007165=TAS, GO:0005737=IEA, GO:0006281=TAS, GO:0004672=ISS, GO:0004674=TAS, GO:0000086=TAS, GO:0030529=IEA, GO:0006468=ISS, GO:0034613=IEA, GO:0000278=TAS} DNA repair, G2/M transition of mitotic cell cycle, cellular protein localization, mitotic cell cycle, negative regulation of Wnt receptor signaling pathway, positive regulation of canonical Wnt receptor signaling pathway, positive regulation of proteasomal ubiquitin-dependent protein catabolic process, protein phosphorylation, signal transduction cytoplasm, cytosol, nucleus, ribonucleoprotein complex ATP binding, protein binding, protein kinase activity, protein serine/threonine kinase activity Human UniProtKB:P08238 CSNK1G1 HPA UniProtKB {GO:0051219=GO_REF:0000019, GO:0042277=GO_REF:0000019, GO:0005737=GO_REF:0000052, GO:0046777=GO_REF:0000019, GO:0001948=GO_REF:0000019, GO:0000287=GO_REF:0000019, GO:0004674=GO_REF:0000019, GO:0016055=GO_REF:0000037, GO:0005524=GO_REF:0000019} Q9HCP0 Casein kinase I isoform gamma-1 protein 20090616 {GO:0051219=IEA, GO:0042277=IEA, GO:0005737=IDA, GO:0046777=IEA, GO:0001948=IEA, GO:0000287=IEA, GO:0004674=IEA, GO:0016055=IEA, GO:0005524=IEA} Wnt receptor signaling pathway, protein autophosphorylation cytoplasm ATP binding, glycoprotein binding, magnesium ion binding, peptide binding, phosphoprotein binding, protein serine/threonine kinase activity Human CSNK1G2 HPA UniProtKB {GO:0051219=GO_REF:0000019, GO:0006665=Reactome:REACT_19323, GO:0042277=GO_REF:0000019, GO:0000287=GO_REF:0000019, GO:0030148=Reactome:REACT_115810, GO:0044281=Reactome:REACT_111217, GO:0005524=GO_REF:0000019, GO:0005829=Reactome:REACT_19156, GO:0007165=PMID:9403068, GO:0005737=GO_REF:0000052, GO:0004672=GO_REF:0000002, GO:0001948=GO_REF:0000019, GO:0046777=GO_REF:0000019, GO:0004674=PMID:9403068, GO:0006468=PMID:9403068, GO:0016055=GO_REF:0000037} P78368 Casein kinase I isoform gamma-2 protein 20110516 {GO:0051219=IEA, GO:0006665=TAS, GO:0042277=IEA, GO:0000287=IEA, GO:0030148=TAS, GO:0044281=TAS, GO:0005524=IEA, GO:0005829=TAS, GO:0007165=TAS, GO:0005737=IDA, GO:0004672=IEA, GO:0001948=IEA, GO:0046777=IEA, GO:0004674=TAS, GO:0006468=TAS, GO:0016055=IEA} Wnt receptor signaling pathway, protein autophosphorylation, protein phosphorylation, signal transduction, small molecule metabolic process, sphingolipid biosynthetic process, sphingolipid metabolic process cytoplasm, cytosol ATP binding, glycoprotein binding, magnesium ion binding, peptide binding, phosphoprotein binding, protein kinase activity, protein serine/threonine kinase activity Human CSNK1G3 PINC UniProtKB {GO:0007165=PMID:9925945, GO:0005737=GO_REF:0000039, GO:0004672=PMID:9925945, GO:0004674=GO_REF:0000037, GO:0016055=GO_REF:0000037, GO:0005524=GO_REF:0000037, GO:0006464=PMID:9925945} Q9Y6M4 Casein kinase I isoform gamma-3 protein 20030904 {GO:0007165=TAS, GO:0005737=IEA, GO:0004672=TAS, GO:0004674=IEA, GO:0016055=IEA, GO:0005524=IEA, GO:0006464=TAS} Wnt receptor signaling pathway, cellular protein modification process, signal transduction cytoplasm ATP binding, protein kinase activity, protein serine/threonine kinase activity Human CSNK2A1 BHF-UCL UniProtKB {GO:0005515=PMID:23455922, GO:0000236=Reactome:REACT_682, GO:0045732=PMID:20625391, GO:0008284=PMID:20625391, GO:0008013=GO_REF:0000019, GO:0005886=PMID:10799509, GO:0030307=PMID:20625391, GO:0051879=PMID:19387550, GO:0030177=PMID:12700239, GO:0005634=PMID:21282530, GO:0005829=Reactome:REACT_150239, GO:0046777=GO_REF:0000019, GO:0019888=GO_REF:0000019, GO:0016581=PMID:17827154, GO:0016580=PMID:17827154, GO:0007411=Reactome:REACT_18266, GO:0000087=Reactome:REACT_910, GO:0071174=PMID:11704824, GO:0016055=GO_REF:0000037, GO:0043154=PMID:16193064, GO:0031519=PMID:21282530, GO:0006355=GO_REF:0000037, GO:0005524=GO_REF:0000037, GO:0006351=GO_REF:0000037, GO:0007165=PMID:2174700, GO:0047485=PMID:11972058, GO:0061077=PMID:19387550, GO:0004674=PMID:20864032, GO:0006468=PMID:20625391, GO:0000278=Reactome:REACT_152} P68400 Casein kinase II subunit alpha protein 20090625 {GO:0005515=IPI, GO:0000236=TAS, GO:0045732=IDA, GO:0008284=IDA, GO:0008013=IEA, GO:0005886=TAS, GO:0030307=IDA, GO:0051879=TAS, GO:0030177=IMP, GO:0005634=IDA, GO:0005829=TAS, GO:0046777=IEA, GO:0019888=IEA, GO:0016581=IDA, GO:0016580=IDA, GO:0007411=TAS, GO:0000087=TAS, GO:0071174=IMP, GO:0016055=IEA, GO:0043154=IMP, GO:0031519=IDA, GO:0006355=IEA, GO:0005524=IEA, GO:0006351=IEA, GO:0007165=TAS, GO:0047485=IPI, GO:0061077=TAS, GO:0004674=IDA, GO:0006468=IDA, GO:0000278=TAS} M phase of mitotic cell cycle, Wnt receptor signaling pathway, axon guidance, chaperone-mediated protein folding, mitotic cell cycle, mitotic prometaphase, mitotic spindle checkpoint, negative regulation of cysteine-type endopeptidase activity involved in apoptotic process, positive regulation of Wnt receptor signaling pathway, positive regulation of cell growth, positive regulation of cell proliferation, positive regulation of protein catabolic process, protein autophosphorylation, protein phosphorylation, regulation of transcription, DNA-dependent, signal transduction, transcription, DNA-dependent NuRD complex, PcG protein complex, Sin3 complex, cytosol, nucleus, plasma membrane ATP binding, Hsp90 protein binding, beta-catenin binding, protein N-terminus binding, protein binding, protein phosphatase regulator activity, protein serine/threonine kinase activity Human CSNK2A2 IntAct UniProtKB {GO:0005515=PMID:23455922, GO:0031519=PMID:21282530, GO:0000236=Reactome:REACT_682, GO:0006355=GO_REF:0000037, GO:0006915=GO_REF:0000037, GO:0005634=PMID:21282530, GO:0005524=GO_REF:0000037, GO:0006351=GO_REF:0000037, GO:0005829=Reactome:REACT_150239, GO:0004672=GO_REF:0000002, GO:0047485=PMID:11972058, GO:0007411=Reactome:REACT_18266, GO:0004674=GO_REF:0000019, GO:0000087=Reactome:REACT_910, GO:0051726=GO_REF:0000019, GO:0071174=PMID:11704824, GO:0000278=Reactome:REACT_152, GO:0016055=GO_REF:0000037} P19784 Casein kinase II subunit alpha' protein 20130415 {GO:0005515=IPI, GO:0031519=IDA, GO:0000236=TAS, GO:0006355=IEA, GO:0006915=IEA, GO:0005634=IDA, GO:0005524=IEA, GO:0006351=IEA, GO:0005829=TAS, GO:0004672=IEA, GO:0047485=IPI, GO:0007411=TAS, GO:0004674=IEA, GO:0000087=TAS, GO:0051726=IEA, GO:0071174=IMP, GO:0000278=TAS, GO:0016055=IEA} M phase of mitotic cell cycle, Wnt receptor signaling pathway, apoptotic process, axon guidance, mitotic cell cycle, mitotic prometaphase, mitotic spindle checkpoint, regulation of cell cycle, regulation of transcription, DNA-dependent, transcription, DNA-dependent PcG protein complex, cytosol, nucleus ATP binding, protein N-terminus binding, protein binding, protein kinase activity, protein serine/threonine kinase activity Human UniProtKB:P68400 CSNK2B UniProtKB UniProtKB {GO:0045859=PMID:2666134, GO:0005515=PMID:23455922, GO:0000236=Reactome:REACT_682, GO:0008285=PMID:19324893, GO:0005886=PMID:19233263, GO:0033211=PMID:19233263, GO:0005634=PMID:21282530, GO:0046872=GO_REF:0000037, GO:0043623=PMID:19324893, GO:0005829=Reactome:REACT_150239, GO:0042802=PMID:21988832, GO:0019887=GO_REF:0000002, GO:0005737=PMID:19233263, GO:0016301=GO_REF:0000038, GO:0007411=Reactome:REACT_18266, GO:0000087=Reactome:REACT_910, GO:0016055=GO_REF:0000037, GO:0005956=GO_REF:0000002, GO:0031519=PMID:21282530, GO:0019904=PMID:11984006, GO:0010862=PMID:19592636, GO:0005102=PMID:19233263, GO:0007165=PMID:2513884, GO:0004674=PMID:1856204, GO:0061154=PMID:19592636, GO:0051101=PMID:19324893, GO:0000278=Reactome:REACT_152, GO:0043537=PMID:19592636, GO:0008134=PMID:19324893} Q5SRQ6 Casein kinase 2, beta polypeptide, isoform CRA_d protein 20130413 {GO:0045859=NAS, GO:0005515=IPI, GO:0000236=TAS, GO:0008285=TAS, GO:0005886=IDA, GO:0033211=IDA, GO:0005634=IDA, GO:0046872=IEA, GO:0043623=NAS, GO:0005829=TAS, GO:0042802=IPI, GO:0019887=IEA, GO:0005737=IDA, GO:0016301=IEA, GO:0007411=TAS, GO:0000087=TAS, GO:0016055=IEA, GO:0005956=IEA, GO:0031519=IDA, GO:0019904=IPI, GO:0010862=IDA, GO:0005102=IPI, GO:0007165=TAS, GO:0004674=TAS, GO:0061154=IMP, GO:0051101=NAS, GO:0000278=TAS, GO:0043537=IDA, GO:0008134=IPI} M phase of mitotic cell cycle, Wnt receptor signaling pathway, adiponectin-mediated signaling pathway, axon guidance, cellular protein complex assembly, endothelial tube morphogenesis, mitotic cell cycle, mitotic prometaphase, negative regulation of blood vessel endothelial cell migration, negative regulation of cell proliferation, positive regulation of pathway-restricted SMAD protein phosphorylation, regulation of DNA binding, regulation of protein kinase activity, signal transduction PcG protein complex, cytoplasm, cytosol, nucleus, plasma membrane, protein kinase CK2 complex identical protein binding, kinase activity, metal ion binding, protein binding, protein domain specific binding, protein kinase regulator activity, protein serine/threonine kinase activity, receptor binding, transcription factor binding Human UniProtKB-KW:KW-0418 CSPG4 Reactome UniProtKB {GO:0048771=GO_REF:0000037, GO:0008347=GO_REF:0000019, GO:0031258=GO_REF:0000039, GO:0009986=PMID:10587647, GO:0019901=PMID:10587647, GO:0005975=Reactome:REACT_474, GO:0005796=Reactome:REACT_121341, GO:0008283=GO_REF:0000019, GO:0050731=PMID:10587647, GO:0005576=Reactome:REACT_121341, GO:0044281=Reactome:REACT_111217, GO:0001525=GO_REF:0000037, GO:0030208=Reactome:REACT_120800, GO:0035556=PMID:10587647, GO:0030207=Reactome:REACT_120888, GO:0000187=GO_REF:0000019, GO:0030206=Reactome:REACT_120989, GO:0016324=GO_REF:0000039, GO:0005887=PMID:8790396, GO:0004871=GO_REF:0000037, GO:0030204=Reactome:REACT_121206, GO:0030203=Reactome:REACT_121408, GO:0007169=GO_REF:0000019, GO:0043202=Reactome:REACT_121272} Q6UVK1 Chondroitin sulfate proteoglycan 4 protein 20130301 {GO:0048771=IEA, GO:0008347=IEA, GO:0031258=IEA, GO:0009986=TAS, GO:0019901=IPI, GO:0005975=TAS, GO:0005796=TAS, GO:0008283=IEA, GO:0050731=IDA, GO:0005576=TAS, GO:0044281=TAS, GO:0001525=IEA, GO:0030208=TAS, GO:0035556=IDA, GO:0030207=TAS, GO:0000187=IEA, GO:0030206=TAS, GO:0016324=IEA, GO:0005887=TAS, GO:0004871=IEA, GO:0030204=TAS, GO:0030203=TAS, GO:0007169=IEA, GO:0043202=TAS} activation of MAPK activity, angiogenesis, carbohydrate metabolic process, cell proliferation, chondroitin sulfate biosynthetic process, chondroitin sulfate catabolic process, chondroitin sulfate metabolic process, dermatan sulfate biosynthetic process, glial cell migration, glycosaminoglycan metabolic process, intracellular signal transduction, positive regulation of peptidyl-tyrosine phosphorylation, small molecule metabolic process, tissue remodeling, transmembrane receptor protein tyrosine kinase signaling pathway Golgi lumen, apical plasma membrane, cell surface, extracellular region, integral to plasma membrane, lamellipodium membrane, lysosomal lumen protein kinase binding, signal transducer activity Human CSPG5 IntAct UniProtKB {GO:0005515=PMID:12885772, GO:0031103=GO_REF:0000019, GO:0005794=PMID:12885772, GO:0005975=Reactome:REACT_474, GO:0005796=Reactome:REACT_121341, GO:0050804=GO_REF:0000019, GO:0005576=Reactome:REACT_121341, GO:0046907=PMID:12885772, GO:0044281=Reactome:REACT_111217, GO:0007399=PMID:12885772, GO:0030208=Reactome:REACT_120800, GO:0030207=Reactome:REACT_120888, GO:0030206=Reactome:REACT_120989, GO:0016020=PMID:9950058, GO:0005887=PMID:9950058, GO:0030660=PMID:12885772, GO:0005789=GO_REF:0000039, GO:0016021=PMID:12885772, GO:0030204=Reactome:REACT_121206, GO:0030203=Reactome:REACT_121408, GO:0008083=PMID:12885772, GO:0040008=GO_REF:0000037, GO:0043202=Reactome:REACT_121272} O95196 Chondroitin sulfate proteoglycan 5 protein 20130415 {GO:0005515=IPI, GO:0031103=IEA, GO:0005794=IDA, GO:0005975=TAS, GO:0005796=TAS, GO:0050804=IEA, GO:0005576=TAS, GO:0046907=TAS, GO:0044281=TAS, GO:0007399=TAS, GO:0030208=TAS, GO:0030207=TAS, GO:0030206=TAS, GO:0016020=TAS, GO:0005887=TAS, GO:0030660=IDA, GO:0005789=IEA, GO:0016021=TAS, GO:0030204=TAS, GO:0030203=TAS, GO:0008083=TAS, GO:0040008=IEA, GO:0043202=TAS} axon regeneration, carbohydrate metabolic process, chondroitin sulfate biosynthetic process, chondroitin sulfate catabolic process, chondroitin sulfate metabolic process, dermatan sulfate biosynthetic process, glycosaminoglycan metabolic process, intracellular transport, nervous system development, regulation of growth, regulation of synaptic transmission, small molecule metabolic process Golgi apparatus, Golgi lumen, Golgi-associated vesicle membrane, endoplasmic reticulum membrane, extracellular region, integral to membrane, integral to plasma membrane, lysosomal lumen, membrane growth factor activity, protein binding Human UniProtKB:Q8BH60 CSPP1 UniProtKB UniProtKB {GO:0005737=GO_REF:0000037, GO:0005813=PMID:21399614, GO:0000922=PMID:19129481, GO:0005874=GO_REF:0000037, GO:0005819=PMID:19129481, GO:0051781=PMID:19129481} Q1MSJ5 Centrosome and spindle pole-associated protein 1 protein 20110804 {GO:0005737=IEA, GO:0005813=IDA, GO:0000922=IDA, GO:0005874=IEA, GO:0005819=IDA, GO:0051781=IMP} positive regulation of cell division centrosome, cytoplasm, microtubule, spindle, spindle pole Human CSRNP1 HPA UniProtKB {GO:0003700=PMID:17726538, GO:0005730=GO_REF:0000052, GO:0048705=GO_REF:0000019, GO:0006915=PMID:11526492, GO:0005634=GO_REF:0000052, GO:0005575=GO_REF:0000015, GO:0009791=GO_REF:0000019, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037, GO:0003674=GO_REF:0000015, GO:0060325=GO_REF:0000019, GO:0045944=PMID:17726538, GO:0060021=GO_REF:0000019, GO:0048008=GO_REF:0000019} Q96S65 Cysteine/serine-rich nuclear protein 1 protein 20111111 {GO:0003700=ISS, GO:0005730=IDA, GO:0048705=IEA, GO:0006915=NAS, GO:0005634=IDA, GO:0005575=ND, GO:0009791=IEA, GO:0003677=IEA, GO:0006351=IEA, GO:0003674=ND, GO:0060325=IEA, GO:0045944=ISS, GO:0060021=IEA, GO:0048008=IEA} apoptotic process, face morphogenesis, palate development, platelet-derived growth factor receptor signaling pathway, positive regulation of transcription from RNA polymerase II promoter, post-embryonic development, skeletal system morphogenesis, transcription, DNA-dependent cellular_component, nucleolus, nucleus DNA binding, molecular_function, sequence-specific DNA binding transcription factor activity NOT Human CSRNP2 IntAct UniProtKB {GO:0005515=PMID:19389623, GO:0003700=PMID:17726538, GO:0019902=PMID:19389623, GO:0010923=PMID:19389623, GO:0045944=PMID:17726538, GO:0006915=GO_REF:0000037, GO:0005634=PMID:19389623, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q9H175 Cysteine/serine-rich nuclear protein 2 protein 20130415 {GO:0005515=IPI, GO:0003700=ISS, GO:0019902=IDA, GO:0010923=IDA, GO:0045944=ISS, GO:0006915=IEA, GO:0005634=IDA, GO:0003677=IEA, GO:0006351=IEA} apoptotic process, negative regulation of phosphatase activity, positive regulation of transcription from RNA polymerase II promoter, transcription, DNA-dependent nucleus DNA binding, phosphatase binding, protein binding, sequence-specific DNA binding transcription factor activity Human UniProtKB:P62136 CSRNP3 UniProtKB UniProtKB {GO:0043065=GO_REF:0000024, GO:0003700=PMID:17726538, GO:0010923=PMID:19389623, GO:0045944=PMID:17726538, GO:0006915=GO_REF:0000037, GO:0005634=PMID:17726538, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q8WYN3 Cysteine/serine-rich nuclear protein 3 protein 20111103 {GO:0043065=ISS, GO:0003700=ISS, GO:0010923=IDA, GO:0045944=ISS, GO:0006915=IEA, GO:0005634=ISS, GO:0003677=IEA, GO:0006351=IEA} apoptotic process, negative regulation of phosphatase activity, positive regulation of apoptotic process, positive regulation of transcription from RNA polymerase II promoter, transcription, DNA-dependent nucleus DNA binding, sequence-specific DNA binding transcription factor activity Human CSRP1 UniProtKB UniProtKB {GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002} P21291 Cysteine and glycine-rich protein 1 protein 20130413 {GO:0005634=IEA, GO:0008270=IEA} nucleus zinc ion binding Human UniProtKB-SubCell:SL-0191 CSRP2 UniProtKB UniProtKB {GO:0003674=GO_REF:0000015, GO:0005634=PMID:8626582, GO:0007275=GO_REF:0000037, GO:0008270=GO_REF:0000002, GO:0030154=PMID:8626582} Q16527 Cysteine and glycine-rich protein 2 protein 20061026 {GO:0003674=ND, GO:0005634=NAS, GO:0007275=IEA, GO:0008270=IEA, GO:0030154=NAS} cell differentiation, multicellular organismal development nucleus molecular_function, zinc ion binding Human CSRP2BP BHF-UCL UniProtKB {GO:0005515=PMID:19060904, GO:0005737=GO_REF:0000039, GO:0043966=PMID:18838386, GO:0016573=GO_REF:0000019, GO:0030274=PMID:10924333, GO:0005671=PMID:18838386, GO:0005634=PMID:10924333, GO:0009790=GO_REF:0000019, GO:0022402=GO_REF:0000019, GO:0004402=PMID:19103755} Q9H8E8 Cysteine-rich protein 2-binding protein protein 20101105 {GO:0005515=IPI, GO:0005737=IEA, GO:0043966=IDA, GO:0016573=IEA, GO:0030274=NAS, GO:0005671=IDA, GO:0005634=IPI, GO:0009790=IEA, GO:0022402=IEA, GO:0004402=IDA} cell cycle process, embryo development, histone H3 acetylation, histone acetylation Ada2/Gcn5/Ada3 transcription activator complex, cytoplasm, nucleus LIM domain binding, histone acetyltransferase activity, protein binding Human CSRP3 BHF-UCL UniProtKB {GO:0005515=PMID:12127981, GO:0030018=PMID:12507422, GO:0031433=PMID:15582318, GO:0042805=PMID:12507422, GO:0005634=GO_REF:0000039, GO:0035995=PMID:12507422, GO:0060048=PMID:12507422, GO:0003300=PMID:12507422, GO:0007519=PMID:7954791, GO:0055003=PMID:12507422, GO:0008270=GO_REF:0000002, GO:0005856=GO_REF:0000039, GO:0008307=PMID:12507422} P50461 Cysteine and glycine-rich protein 3 protein 20120927 {GO:0005515=IPI, GO:0030018=IDA, GO:0031433=IPI, GO:0042805=ISS, GO:0005634=IEA, GO:0035995=IMP, GO:0060048=IMP, GO:0003300=IMP, GO:0007519=TAS, GO:0055003=ISS, GO:0008270=IEA, GO:0005856=IEA, GO:0008307=IMP} cardiac muscle contraction, cardiac muscle hypertrophy, cardiac myofibril assembly, detection of muscle stretch, skeletal muscle tissue development Z disc, cytoskeleton, nucleus actinin binding, protein binding, structural constituent of muscle, telethonin binding, zinc ion binding Human CST1 UniProtKB UniProtKB {GO:0004869=GO_REF:0000037, GO:0005576=GO_REF:0000039} P01037 Cystatin-SN protein 20130413 {GO:0004869=IEA, GO:0005576=IEA} extracellular region cysteine-type endopeptidase inhibitor activity Human UniProtKB-SubCell:SL-0243 CST11 UniProtKB UniProtKB {GO:0005737=GO_REF:0000039, GO:0004869=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0042742=GO_REF:0000037} Q9H112 Cystatin-11 protein 20130413 {GO:0005737=IEA, GO:0004869=IEA, GO:0005634=IEA, GO:0042742=IEA} defense response to bacterium cytoplasm, nucleus cysteine-type endopeptidase inhibitor activity Human UniProtKB-SubCell:SL-0086 CST2 UniProtKB UniProtKB {GO:0004869=GO_REF:0000037, GO:0005576=GO_REF:0000039} P09228 Cystatin-SA protein 20130413 {GO:0004869=IEA, GO:0005576=IEA} extracellular region cysteine-type endopeptidase inhibitor activity Human UniProtKB-SubCell:SL-0243 CST3 GOC UniProtKB {GO:0005515=PMID:15127951, GO:0048471=GO_REF:0000019, GO:0008284=GO_REF:0000019, GO:0010711=PMID:10545518, GO:0004869=PMID:6203523, GO:0070301=GO_REF:0000019, GO:0004866=PMID:15127951, GO:0005783=GO_REF:0000019, GO:0010466=PMID:6203523, GO:0001654=GO_REF:0000019, GO:0002020=PMID:6203523, GO:0005615=PMID:18613859, GO:0048678=GO_REF:0000019, GO:0005764=GO_REF:0000019, GO:0010716=PMID:10545518, GO:0042747=GO_REF:0000019, GO:0009743=GO_REF:0000019, GO:0001540=PMID:18026102, GO:0060009=GO_REF:0000019, GO:0043067=GO_REF:0000019, GO:0060313=PMID:10545518, GO:0043292=GO_REF:0000019, GO:0060548=GO_REF:0000019, GO:0043025=GO_REF:0000019, GO:0031667=GO_REF:0000019, GO:0007431=GO_REF:0000019, GO:0060311=PMID:10545518, GO:0043206=PMID:18026102, GO:0032355=GO_REF:0000019, GO:0001775=GO_REF:0000019, GO:0001666=GO_REF:0000019, GO:0031965=GO_REF:0000019, GO:0010703=PMID:7890620, GO:0007566=GO_REF:0000019, GO:0005771=GO_REF:0000019, GO:0042493=GO_REF:0000019, GO:0045740=GO_REF:0000019, GO:0009636=GO_REF:0000019, GO:0006915=GO_REF:0000019, GO:0006952=PMID:6203523, GO:0005576=PMID:18026102, GO:0031982=GO_REF:0000019, GO:0005604=GO_REF:0000019, GO:0010951=PMID:15127951, GO:0033267=GO_REF:0000019, GO:0034103=PMID:10545518, GO:0007420=GO_REF:0000019} P01034 Cystatin-C protein 20130413 {GO:0005515=IPI, GO:0048471=IEA, GO:0008284=IEA, GO:0010711=IEP, GO:0004869=IDA, GO:0070301=IEA, GO:0004866=IDA, GO:0005783=IEA, GO:0010466=IDA, GO:0001654=IEA, GO:0002020=IPI, GO:0005615=IDA, GO:0048678=IEA, GO:0005764=IEA, GO:0010716=IEP, GO:0042747=IEA, GO:0009743=IEA, GO:0001540=IPI, GO:0060009=IEA, GO:0043067=IEA, GO:0060313=IEP, GO:0043292=IEA, GO:0060548=IEA, GO:0043025=IEA, GO:0031667=IEA, GO:0007431=IEA, GO:0060311=IMP, GO:0043206=IGI, GO:0032355=IEA, GO:0001775=IEA, GO:0001666=IEA, GO:0031965=IEA, GO:0010703=IC, GO:0007566=IEA, GO:0005771=IEA, GO:0042493=IEA, GO:0045740=IEA, GO:0009636=IEA, GO:0006915=IEA, GO:0006952=IDA, GO:0005576=IMP, GO:0031982=IEA, GO:0005604=IEA, GO:0010951=IDA, GO:0033267=IEA, GO:0034103=IEP, GO:0007420=IEA} Sertoli cell development, apoptotic process, brain development, cell activation, cellular response to hydrogen peroxide, circadian sleep/wake cycle, REM sleep, defense response, embryo implantation, extracellular fibril organization, eye development, negative regulation of blood vessel remodeling, negative regulation of cell death, negative regulation of collagen catabolic process, negative regulation of elastin catabolic process, negative regulation of endopeptidase activity, negative regulation of extracellular matrix disassembly, negative regulation of histolysis, negative regulation of peptidase activity, positive regulation of DNA replication, positive regulation of cell proliferation, regulation of programmed cell death, regulation of tissue remodeling, response to axon injury, response to carbohydrate stimulus, response to drug, response to estradiol stimulus, response to hypoxia, response to nutrient levels, response to toxic substance, salivary gland development axon part, basement membrane, contractile fiber, endoplasmic reticulum, extracellular region, extracellular space, lysosome, multivesicular body, neuronal cell body, nuclear membrane, perinuclear region of cytoplasm, vesicle beta-amyloid binding, cysteine-type endopeptidase inhibitor activity, endopeptidase inhibitor activity, protease binding, protein binding Human CST4 UniProtKB UniProtKB {GO:0004869=GO_REF:0000037, GO:0005576=GO_REF:0000039} P01036 Cystatin-S protein 20130413 {GO:0004869=IEA, GO:0005576=IEA} extracellular region cysteine-type endopeptidase inhibitor activity Human UniProtKB-SubCell:SL-0243 CST5 UniProtKB UniProtKB {GO:0005515=PMID:8083219, GO:0004869=PMID:8083219, GO:0005576=PMID:8083219} P28325 Cystatin-D protein 20081014 {GO:0005515=IPI, GO:0004869=IDA, GO:0005576=IDA} extracellular region cysteine-type endopeptidase inhibitor activity, protein binding Human UniProtKB:P07858 CST6 PINC UniProtKB {GO:0004869=GO_REF:0000037, GO:0008544=GO_REF:0000019, GO:0005576=GO_REF:0000039, GO:0009653=PMID:9099741, GO:0001533=GO_REF:0000019} Q15828 Cystatin-M protein 20031119 {GO:0004869=IEA, GO:0008544=IEA, GO:0005576=IEA, GO:0009653=TAS, GO:0001533=IEA} anatomical structure morphogenesis, epidermis development cornified envelope, extracellular region cysteine-type endopeptidase inhibitor activity Human CST7 GOC UniProtKB {GO:0010951=PMID:9632704, GO:0006955=PMID:9632704, GO:0005737=GO_REF:0000039, GO:0004869=GO_REF:0000037, GO:0004866=PMID:9632704, GO:0005576=GO_REF:0000039} O76096 Cystatin-F protein 20130413 {GO:0010951=TAS, GO:0006955=TAS, GO:0005737=IEA, GO:0004869=IEA, GO:0004866=TAS, GO:0005576=IEA} immune response, negative regulation of endopeptidase activity cytoplasm, extracellular region cysteine-type endopeptidase inhibitor activity, endopeptidase inhibitor activity Human CST9L UniProtKB UniProtKB {GO:0004869=GO_REF:0000037, GO:0005576=GO_REF:0000039} Q9H4G1 Cystatin-9-like protein 20130413 {GO:0004869=IEA, GO:0005576=IEA} extracellular region cysteine-type endopeptidase inhibitor activity Human UniProtKB-SubCell:SL-0243 CSTA HPA UniProtKB {GO:0005622=GO_REF:0000002, GO:0005737=GO_REF:0000052, GO:0016337=PMID:21944047, GO:0018149=PMID:10908733, GO:0004869=PMID:6203523, GO:0030216=PMID:10908733, GO:0005198=PMID:10908733, GO:0010466=PMID:6203523, GO:0005634=GO_REF:0000052, GO:0002020=PMID:6203523, GO:0030674=PMID:10908733, GO:0001533=PMID:10908733} P01040 Cystatin-A protein 20101115 {GO:0005622=IEA, GO:0005737=IDA, GO:0016337=IMP, GO:0018149=IDA, GO:0004869=IDA, GO:0030216=IDA, GO:0005198=IDA, GO:0010466=IDA, GO:0005634=IDA, GO:0002020=IPI, GO:0030674=IDA, GO:0001533=IDA} cell-cell adhesion, keratinocyte differentiation, negative regulation of peptidase activity, peptide cross-linking cornified envelope, cytoplasm, intracellular, nucleus cysteine-type endopeptidase inhibitor activity, protease binding, protein binding, bridging, structural molecule activity Human CSTB GOC UniProtKB {GO:0010951=PMID:3053245, GO:0008344=GO_REF:0000019, GO:0005737=GO_REF:0000052, GO:0004869=PMID:6203523, GO:0004866=PMID:3053245, GO:0010466=PMID:6203523, GO:0005730=GO_REF:0000052, GO:0042981=GO_REF:0000019, GO:0002020=PMID:6203523} P04080 Cystatin-B protein 20130413 {GO:0010951=TAS, GO:0008344=IEA, GO:0005737=IDA, GO:0004869=IDA, GO:0004866=TAS, GO:0010466=IDA, GO:0005730=IDA, GO:0042981=IEA, GO:0002020=IPI} adult locomotory behavior, negative regulation of endopeptidase activity, negative regulation of peptidase activity, regulation of apoptotic process cytoplasm, nucleolus cysteine-type endopeptidase inhibitor activity, endopeptidase inhibitor activity, protease binding Human CSTF1 IntAct UniProtKB {GO:0005515=PMID:21903422, GO:0006379=PMID:1358884, GO:0008380=Reactome:REACT_1735, GO:0006378=PMID:1358884, GO:0006396=PMID:1741396, GO:0006369=Reactome:REACT_894, GO:0010467=Reactome:REACT_71, GO:0006366=Reactome:REACT_1366, GO:0003723=PMID:1741396, GO:0031124=Reactome:REACT_1849, GO:0005634=PMID:1358884, GO:0000398=Reactome:REACT_467, GO:0005654=Reactome:REACT_1935} Q05048 Cleavage stimulation factor subunit 1 protein 20130415 {GO:0005515=IPI, GO:0006379=TAS, GO:0008380=TAS, GO:0006378=TAS, GO:0006396=TAS, GO:0006369=TAS, GO:0010467=TAS, GO:0006366=TAS, GO:0003723=TAS, GO:0031124=TAS, GO:0005634=TAS, GO:0000398=TAS, GO:0005654=TAS} RNA processing, RNA splicing, gene expression, mRNA 3'-end processing, mRNA cleavage, mRNA polyadenylation, mRNA splicing, via spliceosome, termination of RNA polymerase II transcription, transcription from RNA polymerase II promoter nucleoplasm, nucleus RNA binding, protein binding Human UniProtKB:Q9H0E2 CSTF2 HPA UniProtKB {GO:0008380=Reactome:REACT_1735, GO:0005515=PMID:18688255, GO:0006379=PMID:1741396, GO:0010467=Reactome:REACT_71, GO:0006369=Reactome:REACT_894, GO:0006378=PMID:1741396, GO:0006366=Reactome:REACT_1366, GO:0003723=GO_REF:0000037, GO:0031124=Reactome:REACT_1849, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0003676=GO_REF:0000002, GO:0071920=PMID:11598190, GO:0000166=GO_REF:0000002, GO:0000398=Reactome:REACT_467, GO:0005847=PMID:18305108, GO:0005654=Reactome:REACT_1935} P33240 Cleavage stimulation factor subunit 2 protein 20080205 {GO:0008380=TAS, GO:0005515=IPI, GO:0006379=TAS, GO:0010467=TAS, GO:0006369=TAS, GO:0006378=TAS, GO:0006366=TAS, GO:0003723=IEA, GO:0031124=TAS, GO:0005730=IDA, GO:0005634=IDA, GO:0003676=IEA, GO:0071920=IDA, GO:0000166=IEA, GO:0000398=TAS, GO:0005847=IDA, GO:0005654=TAS} RNA splicing, gene expression, mRNA 3'-end processing, mRNA cleavage, mRNA polyadenylation, mRNA splicing, via spliceosome, termination of RNA polymerase II transcription, transcription from RNA polymerase II promoter cleavage body, mRNA cleavage and polyadenylation specificity factor complex, nucleolus, nucleoplasm, nucleus RNA binding, nucleic acid binding, nucleotide binding, protein binding NOT Human CSTF2T LIFEdb UniProtKB {GO:0005622=GO_REF:0000054, GO:0006397=GO_REF:0000037, GO:0000166=GO_REF:0000002, GO:0003723=GO_REF:0000019, GO:0005634=GO_REF:0000039} Q9H0L4 Cleavage stimulation factor subunit 2 tau variant protein 20100607 {GO:0005622=IDA, GO:0006397=IEA, GO:0000166=IEA, GO:0003723=IEA, GO:0005634=IEA} mRNA processing intracellular, nucleus RNA binding, nucleotide binding Human CSTF3 HPA UniProtKB {GO:0006379=PMID:7984242, GO:0008380=Reactome:REACT_1735, GO:0006396=GO_REF:0000002, GO:0006378=PMID:7984242, GO:0006369=Reactome:REACT_894, GO:0010467=Reactome:REACT_71, GO:0006366=Reactome:REACT_1366, GO:0003723=PMID:1741396, GO:0005730=GO_REF:0000052, GO:0031124=Reactome:REACT_1849, GO:0005634=GO_REF:0000052, GO:0005622=GO_REF:0000002, GO:0000398=Reactome:REACT_467, GO:0005654=Reactome:REACT_1935} Q12996 Cleavage stimulation factor subunit 3 protein 20111111 {GO:0006379=TAS, GO:0008380=TAS, GO:0006396=IEA, GO:0006378=TAS, GO:0006369=TAS, GO:0010467=TAS, GO:0006366=TAS, GO:0003723=TAS, GO:0005730=IDA, GO:0031124=TAS, GO:0005634=IDA, GO:0005622=IEA, GO:0000398=TAS, GO:0005654=TAS} RNA processing, RNA splicing, gene expression, mRNA 3'-end processing, mRNA cleavage, mRNA polyadenylation, mRNA splicing, via spliceosome, termination of RNA polymerase II transcription, transcription from RNA polymerase II promoter intracellular, nucleolus, nucleoplasm, nucleus RNA binding NOT Human CTAG1A LIFEdb UniProtKB {GO:0005737=GO_REF:0000054} P78358 Cancer/testis antigen 1 protein 20100607 {GO:0005737=IDA} cytoplasm Human CTAG1B null null {} null null null null {} null null null CTAG2 LIFEdb UniProtKB {GO:0003674=GO_REF:0000015, GO:0008150=GO_REF:0000015, GO:0005813=GO_REF:0000054} O75638 Cancer/testis antigen 2 protein 20100607 {GO:0003674=ND, GO:0008150=ND, GO:0005813=IDA} biological_process centrosome molecular_function Human CTAGE1 UniProtKB UniProtKB {GO:0008150=GO_REF:0000015, GO:0005575=GO_REF:0000015, GO:0016021=GO_REF:0000037} Q9HC47 Cutaneous T-cell lymphoma-associated antigen 1 protein 20061026 {GO:0008150=ND, GO:0005575=ND, GO:0016021=IEA} biological_process cellular_component, integral to membrane Human CTAGE5 GOC UniProtKB {GO:0043085=PMID:9356211, GO:0008047=PMID:9356211} O15320 Cutaneous T-cell lymphoma-associated antigen 5 protein 20130413 {GO:0043085=TAS, GO:0008047=TAS} positive regulation of catalytic activity enzyme activator activity Human CTBP1 BHF-UCL UniProtKB {GO:0005515=PMID:16287852, GO:0034401=PMID:21102443, GO:0003700=GO_REF:0000019, GO:0008285=PMID:7479821, GO:0090241=PMID:21102443, GO:0005634=GO_REF:0000052, GO:0035067=PMID:21102443, GO:0019079=PMID:7479821, GO:0042803=GO_REF:0000019, GO:0005829=GO_REF:0000019, GO:0051287=GO_REF:0000024, GO:0017053=PMID:19162039, GO:0070491=PMID:19162039, GO:0051726=PMID:21102443, GO:0007030=GO_REF:0000019, GO:0005667=GO_REF:0000019, GO:0048037=GO_REF:0000002, GO:0001106=PMID:19162039, GO:0019904=PMID:19162039, GO:0005730=GO_REF:0000052, GO:0000122=PMID:19162039, GO:0008022=PMID:8440238, GO:0016616=GO_REF:0000002, GO:0050872=GO_REF:0000024, GO:0031065=PMID:21102443, GO:0019048=GO_REF:0000037, GO:0006468=PMID:8440238, GO:0045892=GO_REF:0000024, GO:0008134=PMID:16609867} Q13363 C-terminal-binding protein 1 protein 20121026 {GO:0005515=IPI, GO:0034401=IMP, GO:0003700=IEA, GO:0008285=TAS, GO:0090241=IMP, GO:0005634=IDA, GO:0035067=IMP, GO:0019079=TAS, GO:0042803=IEA, GO:0005829=IEA, GO:0051287=ISS, GO:0017053=IDA, GO:0070491=IPI, GO:0051726=IMP, GO:0007030=IEA, GO:0005667=IEA, GO:0048037=IEA, GO:0001106=IDA, GO:0019904=IDA, GO:0005730=IDA, GO:0000122=IMP, GO:0008022=TAS, GO:0016616=IEA, GO:0050872=ISS, GO:0031065=IMP, GO:0019048=IEA, GO:0006468=TAS, GO:0045892=ISS, GO:0008134=IPI} Golgi organization, negative regulation of cell proliferation, negative regulation of histone H4 acetylation, negative regulation of histone acetylation, negative regulation of transcription from RNA polymerase II promoter, negative regulation of transcription, DNA-dependent, positive regulation of histone deacetylation, protein phosphorylation, regulation of cell cycle, regulation of transcription by chromatin organization, viral genome replication, virus-host interaction, white fat cell differentiation cytosol, nucleolus, nucleus, transcription factor complex, transcriptional repressor complex NAD binding, RNA polymerase II transcription corepressor activity, cofactor binding, oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor, protein C-terminus binding, protein binding, protein domain specific binding, protein homodimerization activity, repressing transcription factor binding, sequence-specific DNA binding transcription factor activity, transcription factor binding Human CTBP2 InterPro UniProtKB {GO:0005515=PMID:21988832, GO:0030054=GO_REF:0000037, GO:0008285=PMID:9479502, GO:0003714=GO_REF:0000019, GO:0045202=GO_REF:0000039, GO:0005634=GO_REF:0000024, GO:0019079=PMID:9479502, GO:0006351=GO_REF:0000037, GO:0016616=GO_REF:0000002, GO:0051287=GO_REF:0000002, GO:0050872=GO_REF:0000024, GO:0017053=GO_REF:0000024, GO:0045892=GO_REF:0000024} Q5SQP8 C-terminal-binding protein 2 protein 20130413 {GO:0005515=IPI, GO:0030054=IEA, GO:0008285=TAS, GO:0003714=IEA, GO:0045202=IEA, GO:0005634=ISS, GO:0019079=TAS, GO:0006351=IEA, GO:0016616=IEA, GO:0051287=IEA, GO:0050872=ISS, GO:0017053=ISS, GO:0045892=ISS} negative regulation of cell proliferation, negative regulation of transcription, DNA-dependent, transcription, DNA-dependent, viral genome replication, white fat cell differentiation cell junction, nucleus, synapse, transcriptional repressor complex NAD binding, oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor, protein binding, transcription corepressor activity Human InterPro:IPR006139 CTBS UniProtKB UniProtKB {GO:0009313=GO_REF:0000019, GO:0006032=GO_REF:0000019, GO:0005764=GO_REF:0000039, GO:0004568=GO_REF:0000019} Q01459 Di-N-acetylchitobiase protein 20130413 {GO:0009313=IEA, GO:0006032=IEA, GO:0005764=IEA, GO:0004568=IEA} chitin catabolic process, oligosaccharide catabolic process lysosome chitinase activity Human UniProtKB-SubCell:SL-0158 CTC1 UniProtKB UniProtKB {GO:0005515=PMID:19854130, GO:0070188=GO_REF:0000024, GO:0000723=PMID:19854131, GO:0003697=GO_REF:0000024, GO:0045740=GO_REF:0000024, GO:0005634=PMID:19854130, GO:0000784=PMID:19854130} Q2NKJ3 CST complex subunit CTC1 protein 20100222 {GO:0005515=IPI, GO:0070188=ISS, GO:0000723=IMP, GO:0003697=ISS, GO:0045740=ISS, GO:0005634=IDA, GO:0000784=IDA} positive regulation of DNA replication, telomere maintenance Stn1-Ten1 complex, nuclear chromosome, telomeric region, nucleus protein binding, single-stranded DNA binding Human UniProtKB:Q8K2X3 CTCF UniProtKB UniProtKB {GO:0005515=PMID:19505873, GO:0000793=PMID:16107875, GO:0003700=PMID:9591631, GO:0044212=PMID:18413740, GO:0005634=PMID:9407128, GO:0035065=GO_REF:0000019, GO:0010216=GO_REF:0000019, GO:0007059=GO_REF:0000037, GO:0016584=PMID:18654629, GO:0070602=PMID:18550811, GO:0003714=PMID:8649389, GO:0005730=PMID:16595548, GO:0006351=GO_REF:0000037, GO:0040030=PMID:16815976, GO:0043565=PMID:17827499, GO:0010628=PMID:18347100, GO:0031060=GO_REF:0000019, GO:0006349=GO_REF:0000019, GO:0040029=PMID:16815976, GO:0043035=PMID:17827499, GO:0008270=PMID:8649389, GO:0005654=PMID:16107875, GO:0045893=PMID:19322193, GO:0045892=PMID:18413740, GO:0000775=PMID:18550811, GO:0016568=GO_REF:0000037} P49711 Transcriptional repressor CTCF protein 20120708 {GO:0005515=IPI, GO:0000793=IDA, GO:0003700=IDA, GO:0044212=IDA, GO:0005634=IDA, GO:0035065=IEA, GO:0010216=IEA, GO:0007059=IEA, GO:0016584=IDA, GO:0070602=NAS, GO:0003714=TAS, GO:0005730=IDA, GO:0006351=IEA, GO:0040030=IMP, GO:0043565=IDA, GO:0010628=IMP, GO:0031060=IEA, GO:0006349=IEA, GO:0040029=IMP, GO:0043035=IDA, GO:0008270=TAS, GO:0005654=IDA, GO:0045893=IMP, GO:0045892=IDA, GO:0000775=IDA, GO:0016568=IEA} chromatin modification, chromosome segregation, maintenance of DNA methylation, negative regulation of transcription, DNA-dependent, nucleosome positioning, positive regulation of gene expression, positive regulation of transcription, DNA-dependent, regulation of centromeric sister chromatid cohesion, regulation of gene expression by genetic imprinting, regulation of gene expression, epigenetic, regulation of histone acetylation, regulation of histone methylation, regulation of molecular function, epigenetic, transcription, DNA-dependent chromosome, centromeric region, condensed chromosome, nucleolus, nucleoplasm, nucleus chromatin insulator sequence binding, protein binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, transcription corepressor activity, transcription regulatory region DNA binding, zinc ion binding Human UniProtKB:Q01664 CTCFL HPA UniProtKB {GO:0005515=PMID:18765639, GO:0044212=PMID:18413740, GO:0016571=GO_REF:0000024, GO:0005634=GO_REF:0000052, GO:0003676=GO_REF:0000002, GO:0003677=PMID:18413740, GO:0006351=GO_REF:0000037, GO:0043565=GO_REF:0000024, GO:0010628=PMID:18413740, GO:0042393=GO_REF:0000024, GO:0005737=GO_REF:0000052, GO:0007049=GO_REF:0000037, GO:0006349=GO_REF:0000024, GO:0008270=GO_REF:0000002, GO:0045893=PMID:18413740, GO:0051569=PMID:18765639, GO:0043046=GO_REF:0000024} Q8NI51 Transcriptional repressor CTCFL protein 20101115 {GO:0005515=IPI, GO:0044212=IDA, GO:0016571=ISS, GO:0005634=IDA, GO:0003676=IEA, GO:0003677=IDA, GO:0006351=IEA, GO:0043565=ISS, GO:0010628=IDA, GO:0042393=ISS, GO:0005737=IDA, GO:0007049=IEA, GO:0006349=ISS, GO:0008270=IEA, GO:0045893=IDA, GO:0051569=IMP, GO:0043046=ISS} DNA methylation involved in gamete generation, cell cycle, histone methylation, positive regulation of gene expression, positive regulation of transcription, DNA-dependent, regulation of gene expression by genetic imprinting, regulation of histone H3-K4 methylation, transcription, DNA-dependent cytoplasm, nucleus DNA binding, histone binding, nucleic acid binding, protein binding, sequence-specific DNA binding, transcription regulatory region DNA binding, zinc ion binding Human CTDNEP1 IntAct UniProtKB {GO:0005515=PMID:22134922, GO:0031965=PMID:22134922, GO:0034504=PMID:22134922, GO:0010867=PMID:22134922, GO:0071595=PMID:22134922, GO:0005635=PMID:17420445, GO:0016791=GO_REF:0000002, GO:0005737=PMID:22134922, GO:0006470=PMID:22134922, GO:0005789=PMID:17420445, GO:0006998=PMID:17420445, GO:0016021=GO_REF:0000037, GO:0004722=PMID:17420445} O95476 CTD nuclear envelope phosphatase 1 protein 20130415 {GO:0005515=IPI, GO:0031965=IDA, GO:0034504=IDA, GO:0010867=IGI, GO:0071595=IDA, GO:0005635=IDA, GO:0016791=IEA, GO:0005737=IDA, GO:0006470=IDA, GO:0005789=IDA, GO:0006998=IDA, GO:0016021=IEA, GO:0004722=IMP} nuclear envelope organization, positive regulation of triglyceride biosynthetic process, protein dephosphorylation, protein localization to nucleus Nem1-Spo7 phosphatase complex, cytoplasm, endoplasmic reticulum membrane, integral to membrane, nuclear envelope, nuclear membrane phosphatase activity, protein binding, protein serine/threonine phosphatase activity Human UniProtKB:Q8N9A8 CTDP1 HPA UniProtKB {GO:0022415=Reactome:REACT_6361, GO:0010467=Reactome:REACT_71, GO:0010458=PMID:22692537, GO:0006368=Reactome:REACT_1845, GO:0005813=PMID:22692537, GO:0006366=Reactome:REACT_1366, GO:0003899=PMID:9765293, GO:0005730=GO_REF:0000052, GO:0005819=PMID:22692537, GO:0030496=PMID:22692537, GO:0005634=GO_REF:0000052, GO:0015629=GO_REF:0000052, GO:0051233=PMID:22692537, GO:0050434=Reactome:REACT_6162, GO:0007067=GO_REF:0000037, GO:0000922=PMID:22692537, GO:0005737=GO_REF:0000037, GO:0006470=PMID:22692537, GO:0016032=Reactome:REACT_6256, GO:0005654=Reactome:REACT_6355, GO:0004721=GO_REF:0000002, GO:0051301=GO_REF:0000037, GO:0008420=PMID:12721286} Q9Y5B0 RNA polymerase II subunit A C-terminal domain phosphatase protein 20110516 {GO:0022415=TAS, GO:0010467=TAS, GO:0010458=IMP, GO:0006368=TAS, GO:0005813=IDA, GO:0006366=TAS, GO:0003899=TAS, GO:0005730=IDA, GO:0005819=IDA, GO:0030496=IDA, GO:0005634=IDA, GO:0015629=IDA, GO:0051233=IDA, GO:0050434=TAS, GO:0007067=IEA, GO:0000922=IDA, GO:0005737=IEA, GO:0006470=IDA, GO:0016032=TAS, GO:0005654=TAS, GO:0004721=IEA, GO:0051301=IEA, GO:0008420=IDA} cell division, exit from mitosis, gene expression, mitosis, positive regulation of viral transcription, protein dephosphorylation, transcription elongation from RNA polymerase II promoter, transcription from RNA polymerase II promoter, viral reproduction, viral reproductive process actin cytoskeleton, centrosome, cytoplasm, midbody, nucleolus, nucleoplasm, nucleus, spindle, spindle midzone, spindle pole CTD phosphatase activity, DNA-directed RNA polymerase activity, phosphoprotein phosphatase activity Human CTDSP1 UniProtKB UniProtKB {GO:0005515=PMID:12721286, GO:0016791=GO_REF:0000002, GO:0006470=PMID:12721286, GO:0006357=PMID:12721286, GO:0045665=GO_REF:0000019, GO:0050768=GO_REF:0000019, GO:0005634=PMID:12721286, GO:0046872=GO_REF:0000037, GO:0008420=PMID:12721286} Q9GZU7 Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1 protein 20091123 {GO:0005515=IPI, GO:0016791=IEA, GO:0006470=IDA, GO:0006357=IDA, GO:0045665=IEA, GO:0050768=IEA, GO:0005634=IDA, GO:0046872=IEA, GO:0008420=IDA} negative regulation of neurogenesis, negative regulation of neuron differentiation, protein dephosphorylation, regulation of transcription from RNA polymerase II promoter nucleus CTD phosphatase activity, metal ion binding, phosphatase activity, protein binding Human CTDSP2 Reactome UniProtKB {GO:0016791=GO_REF:0000002, GO:0006470=PMID:12721286, GO:0005654=Reactome:REACT_115909, GO:0006987=Reactome:REACT_18368, GO:0044267=Reactome:REACT_17015, GO:0046872=GO_REF:0000037, GO:0030968=Reactome:REACT_18356, GO:0008420=PMID:12721286} O14595 Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 2 protein 20130301 {GO:0016791=IEA, GO:0006470=IDA, GO:0005654=TAS, GO:0006987=TAS, GO:0044267=TAS, GO:0046872=IEA, GO:0030968=TAS, GO:0008420=IDA} activation of signaling protein activity involved in unfolded protein response, cellular protein metabolic process, endoplasmic reticulum unfolded protein response, protein dephosphorylation nucleoplasm CTD phosphatase activity, metal ion binding, phosphatase activity Human CTDSPL UniProtKB UniProtKB {GO:0003674=GO_REF:0000015, GO:0008150=GO_REF:0000015, GO:0016791=GO_REF:0000002, GO:0005634=GO_REF:0000039, GO:0004721=GO_REF:0000003, GO:0005575=GO_REF:0000015, GO:0046872=GO_REF:0000037} O15194 CTD small phosphatase-like protein protein 20061026 {GO:0003674=ND, GO:0008150=ND, GO:0016791=IEA, GO:0005634=IEA, GO:0004721=IEA, GO:0005575=ND, GO:0046872=IEA} biological_process cellular_component, nucleus metal ion binding, molecular_function, phosphatase activity, phosphoprotein phosphatase activity Human CTDSPL2 UniProtKB UniProtKB {GO:0004721=GO_REF:0000037} Q05D32 CTD small phosphatase-like protein 2 protein 20130413 {GO:0004721=IEA} phosphoprotein phosphatase activity Human UniProtKB-KW:KW-0904 CTF1 PINC UniProtKB {GO:0005146=GO_REF:0000019, GO:0008284=PMID:7862649, GO:0048861=GO_REF:0000019, GO:0007517=PMID:8833032, GO:0008283=PMID:7738033, GO:0048666=GO_REF:0000019, GO:0007267=PMID:7862649, GO:0005576=PMID:7862649, GO:0005615=GO_REF:0000037, GO:0005125=GO_REF:0000037, GO:0007399=PMID:7738033} Q16619 Cardiotrophin-1 protein 20030904 {GO:0005146=IEA, GO:0008284=TAS, GO:0048861=IEA, GO:0007517=TAS, GO:0008283=TAS, GO:0048666=IEA, GO:0007267=TAS, GO:0005576=TAS, GO:0005615=IEA, GO:0005125=IEA, GO:0007399=TAS} cell proliferation, cell-cell signaling, leukemia inhibitory factor signaling pathway, muscle organ development, nervous system development, neuron development, positive regulation of cell proliferation extracellular region, extracellular space cytokine activity, leukemia inhibitory factor receptor binding Human CTGF HPA UniProtKB {GO:0060401=GO_REF:0000019, GO:0010467=Reactome:REACT_71, GO:0005801=GO_REF:0000019, GO:0006367=Reactome:REACT_118713, GO:0070278=GO_REF:0000019, GO:0001558=GO_REF:0000002, GO:0005615=GO_REF:0000019, GO:0035988=GO_REF:0000019, GO:0030154=GO_REF:0000019, GO:0043231=GO_REF:0000052, GO:0010942=GO_REF:0000019, GO:0005938=GO_REF:0000019, GO:0032355=GO_REF:0000019, GO:0044255=Reactome:REACT_22279, GO:0005520=GO_REF:0000002, GO:0005794=GO_REF:0000052, GO:0034059=GO_REF:0000019, GO:0051385=GO_REF:0000019, GO:0032330=GO_REF:0000019, GO:0043280=GO_REF:0000019, GO:0005178=GO_REF:0000019, GO:0070542=GO_REF:0000019, GO:0032967=GO_REF:0000019, GO:0001503=GO_REF:0000019, GO:0008544=PMID:10809757, GO:0001502=GO_REF:0000019, GO:0007229=GO_REF:0000019, GO:0008543=GO_REF:0000019, GO:0008083=GO_REF:0000019, GO:0008284=GO_REF:0000019, GO:0048471=GO_REF:0000019, GO:0005886=PMID:10809757, GO:0030324=GO_REF:0000019, GO:0043434=GO_REF:0000019, GO:0044281=Reactome:REACT_111217, GO:0005829=GO_REF:0000019, GO:0035556=GO_REF:0000019, GO:0010260=GO_REF:0000019, GO:0060452=GO_REF:0000019, GO:0001968=GO_REF:0000019, GO:0008201=GO_REF:0000019, GO:0043200=GO_REF:0000019, GO:0050867=GO_REF:0000019, GO:0072593=GO_REF:0000019, GO:0005578=GO_REF:0000039, GO:0009611=PMID:10809757, GO:0005576=Reactome:REACT_116163, GO:0070318=GO_REF:0000019, GO:0001525=GO_REF:0000019, GO:0009749=GO_REF:0000019, GO:0010628=GO_REF:0000019, GO:0006260=GO_REF:0000037, GO:0007160=GO_REF:0000019, GO:0016477=GO_REF:0000019, GO:0010629=GO_REF:0000019, GO:0001934=GO_REF:0000019} P29279 Connective tissue growth factor protein 20111111 {GO:0060401=IEA, GO:0010467=TAS, GO:0005801=IEA, GO:0006367=TAS, GO:0070278=IEA, GO:0001558=IEA, GO:0005615=IEA, GO:0035988=IEA, GO:0030154=IEA, GO:0043231=IDA, GO:0010942=IEA, GO:0005938=IEA, GO:0032355=IEA, GO:0044255=TAS, GO:0005520=IEA, GO:0005794=IDA, GO:0034059=IEA, GO:0051385=IEA, GO:0032330=IEA, GO:0043280=IEA, GO:0005178=IEA, GO:0070542=IEA, GO:0032967=IEA, GO:0001503=IEA, GO:0008544=TAS, GO:0001502=IEA, GO:0007229=IEA, GO:0008543=IEA, GO:0008083=IEA, GO:0008284=IEA, GO:0048471=IEA, GO:0005886=TAS, GO:0030324=IEA, GO:0043434=IEA, GO:0044281=TAS, GO:0005829=IEA, GO:0035556=IEA, GO:0010260=IEA, GO:0060452=IEA, GO:0001968=IEA, GO:0008201=IEA, GO:0043200=IEA, GO:0050867=IEA, GO:0072593=IEA, GO:0005578=IEA, GO:0009611=TAS, GO:0005576=TAS, GO:0070318=IEA, GO:0001525=IEA, GO:0009749=IEA, GO:0010628=IEA, GO:0006260=IEA, GO:0007160=IEA, GO:0016477=IEA, GO:0010629=IEA, GO:0001934=IEA} DNA replication, angiogenesis, cartilage condensation, cell differentiation, cell migration, cell-matrix adhesion, cellular lipid metabolic process, chondrocyte proliferation, cytosolic calcium ion transport, epidermis development, extracellular matrix constituent secretion, fibroblast growth factor receptor signaling pathway, gene expression, integrin-mediated signaling pathway, intracellular signal transduction, lung development, negative regulation of gene expression, organ senescence, ossification, positive regulation of G0 to G1 transition, positive regulation of cardiac muscle contraction, positive regulation of cell activation, positive regulation of cell death, positive regulation of cell proliferation, positive regulation of collagen biosynthetic process, positive regulation of cysteine-type endopeptidase activity involved in apoptotic process, positive regulation of gene expression, positive regulation of protein phosphorylation, reactive oxygen species metabolic process, regulation of cell growth, regulation of chondrocyte differentiation, response to amino acid stimulus, response to anoxia, response to estradiol stimulus, response to fatty acid, response to glucose stimulus, response to mineralocorticoid stimulus, response to peptide hormone stimulus, response to wounding, small molecule metabolic process, transcription initiation from RNA polymerase II promoter Golgi apparatus, cell cortex, cis-Golgi network, cytosol, extracellular region, extracellular space, intracellular membrane-bounded organelle, perinuclear region of cytoplasm, plasma membrane, proteinaceous extracellular matrix fibronectin binding, growth factor activity, heparin binding, insulin-like growth factor binding, integrin binding Human CTH HPA UniProtKB {GO:0005515=PMID:22169477, GO:0019344=PMID:10212249, GO:0005516=GO_REF:0000037, GO:0070814=PMID:19019829, GO:0019346=Reactome:REACT_115589, GO:0006534=PMID:1339280, GO:0005634=GO_REF:0000052, GO:0044540=PMID:22169477, GO:0044281=Reactome:REACT_111217, GO:0003824=GO_REF:0000002, GO:0030968=PMID:22169477, GO:0005829=Reactome:REACT_116121, GO:0018272=PMID:19019829, GO:0034641=Reactome:REACT_13, GO:0005737=GO_REF:0000052, GO:0051092=GO_REF:0000019, GO:0051289=PMID:19019829, GO:0004123=Reactome:REACT_116098, GO:0043123=GO_REF:0000019, GO:0016846=Reactome:REACT_115918, GO:0043066=GO_REF:0000019, GO:0047982=Reactome:REACT_116033, GO:0080146=Reactome:REACT_116121, GO:0000096=Reactome:REACT_115639, GO:0000098=Reactome:REACT_115654, GO:0030170=PMID:10212249, GO:0044524=PMID:22169477} P32929 Cystathionine gamma-lyase protein 20100326 {GO:0005515=IPI, GO:0019344=IDA, GO:0005516=IEA, GO:0070814=IDA, GO:0019346=TAS, GO:0006534=TAS, GO:0005634=IDA, GO:0044540=IMP, GO:0044281=TAS, GO:0003824=IEA, GO:0030968=TAS, GO:0005829=TAS, GO:0018272=IDA, GO:0034641=TAS, GO:0005737=IDA, GO:0051092=IEA, GO:0051289=IPI, GO:0004123=TAS, GO:0043123=IEA, GO:0016846=TAS, GO:0043066=IEA, GO:0047982=TAS, GO:0080146=TAS, GO:0000096=TAS, GO:0000098=TAS, GO:0030170=IDA, GO:0044524=IMP} cellular nitrogen compound metabolic process, cysteine biosynthetic process, cysteine metabolic process, endoplasmic reticulum unfolded protein response, hydrogen sulfide biosynthetic process, negative regulation of apoptotic process, positive regulation of I-kappaB kinase/NF-kappaB cascade, positive regulation of NF-kappaB transcription factor activity, protein homotetramerization, protein sulfhydration, protein-pyridoxal-5-phosphate linkage via peptidyl-N6-pyridoxal phosphate-L-lysine, small molecule metabolic process, sulfur amino acid catabolic process, sulfur amino acid metabolic process, transsulfuration cytoplasm, cytosol, nucleus L-cysteine desulfhydrase activity, L-cystine L-cysteine-lyase (deaminating), calmodulin binding, carbon-sulfur lyase activity, catalytic activity, cystathionine gamma-lyase activity, homocysteine desulfhydrase activity, protein binding, pyridoxal phosphate binding Human CTHRC1 MGI UniProtKB {GO:0017147=GO_REF:0000019, GO:0005581=GO_REF:0000037, GO:0043932=GO_REF:0000019, GO:0060122=GO_REF:0000019, GO:0090177=GO_REF:0000019, GO:0005615=PMID:18467647, GO:0032092=GO_REF:0000019, GO:0005109=GO_REF:0000019, GO:0031012=GO_REF:0000019, GO:0045669=GO_REF:0000019, GO:0005737=GO_REF:0000019, GO:0016477=GO_REF:0000019, GO:0090103=GO_REF:0000019, GO:0033690=GO_REF:0000019, GO:0090090=GO_REF:0000019, GO:0060071=GO_REF:0000019} Q96CG8 Collagen triple helix repeat-containing protein 1 protein 20111227 {GO:0017147=IEA, GO:0005581=IEA, GO:0043932=IEA, GO:0060122=IEA, GO:0090177=IEA, GO:0005615=IDA, GO:0032092=IEA, GO:0005109=IEA, GO:0031012=IEA, GO:0045669=IEA, GO:0005737=IEA, GO:0016477=IEA, GO:0090103=IEA, GO:0033690=IEA, GO:0090090=IEA, GO:0060071=IEA} Wnt receptor signaling pathway, planar cell polarity pathway, cell migration, cochlea morphogenesis, establishment of planar polarity involved in neural tube closure, inner ear receptor stereocilium organization, negative regulation of canonical Wnt receptor signaling pathway, ossification involved in bone remodeling, positive regulation of osteoblast differentiation, positive regulation of osteoblast proliferation, positive regulation of protein binding collagen, cytoplasm, extracellular matrix, extracellular space Wnt-protein binding, frizzled binding Human CTIF HPA UniProtKB {GO:0005515=PMID:19648179, GO:0005737=GO_REF:0000052, GO:0048471=PMID:19648179, GO:0000184=PMID:19648179, GO:0003723=GO_REF:0000002, GO:0006446=PMID:19648179, GO:0003677=GO_REF:0000002} O43310 CBP80/20-dependent translation initiation factor protein 20100326 {GO:0005515=IPI, GO:0005737=IDA, GO:0048471=IDA, GO:0000184=IMP, GO:0003723=IEA, GO:0006446=IMP, GO:0003677=IEA} nuclear-transcribed mRNA catabolic process, nonsense-mediated decay, regulation of translational initiation cytoplasm, perinuclear region of cytoplasm DNA binding, RNA binding, protein binding Human CTLA4 BHF-UCL UniProtKB {GO:0050853=PMID:17875758, GO:0005515=PMID:21982860, GO:0048471=PMID:15814706, GO:0043065=PMID:17875758, GO:0005794=PMID:15814706, GO:0005886=Reactome:REACT_19404, GO:0031295=Reactome:REACT_19344, GO:0030889=PMID:17875758, GO:0006974=PMID:17875758, GO:0006955=GO_REF:0000002, GO:0045334=PMID:15814706, GO:0005887=PMID:3220103, GO:0045590=PMID:18641304, GO:0009897=PMID:18641304} P16410 Cytotoxic T-lymphocyte protein 4 protein 20081121 {GO:0050853=IMP, GO:0005515=IPI, GO:0048471=IDA, GO:0043065=IMP, GO:0005794=IDA, GO:0005886=TAS, GO:0031295=TAS, GO:0030889=IMP, GO:0006974=IMP, GO:0006955=IEA, GO:0045334=IDA, GO:0005887=TAS, GO:0045590=IDA, GO:0009897=IDA} B cell receptor signaling pathway, T cell costimulation, immune response, negative regulation of B cell proliferation, negative regulation of regulatory T cell differentiation, positive regulation of apoptotic process, response to DNA damage stimulus Golgi apparatus, clathrin-coated endocytic vesicle, external side of plasma membrane, integral to plasma membrane, perinuclear region of cytoplasm, plasma membrane protein binding Human CTNNA1 ENSEMBL UniProtKB {GO:0005515=PMID:12477722, GO:0031103=GO_REF:0000019, GO:0043627=GO_REF:0000019, GO:0008013=PMID:7650039, GO:0005886=GO_REF:0000019, GO:0016342=PMID:7650039, GO:0016264=GO_REF:0000019, GO:0015629=GO_REF:0000002, GO:0051291=GO_REF:0000019, GO:0007406=GO_REF:0000019, GO:0005829=Reactome:REACT_21371, GO:0042692=Reactome:REACT_21303, GO:0043297=GO_REF:0000019, GO:0005915=GO_REF:0000019, GO:0045880=GO_REF:0000019, GO:0071681=PMID:10868478, GO:0001541=GO_REF:0000019, GO:0051015=GO_REF:0000019, GO:0014704=GO_REF:0000019, GO:0005911=PMID:7650039, GO:0042475=GO_REF:0000019, GO:0007155=GO_REF:0000002, GO:0043066=GO_REF:0000019, GO:0045296=GO_REF:0000002, GO:0045295=PMID:7890674, GO:0001669=GO_REF:0000019, GO:0034329=Reactome:REACT_20676, GO:0007568=GO_REF:0000019, GO:0045216=Reactome:REACT_19331, GO:0030027=GO_REF:0000019, GO:0051149=Reactome:REACT_21402, GO:0007163=GO_REF:0000019, GO:0005198=GO_REF:0000002, GO:0017166=PMID:9700171, GO:0008584=GO_REF:0000019, GO:0034332=Reactome:REACT_19195} Q8N1C0 Catenin alpha 1 isoform CTNNA1b protein 20130413 {GO:0005515=IPI, GO:0031103=IEA, GO:0043627=IEA, GO:0008013=IPI, GO:0005886=IEA, GO:0016342=IDA, GO:0016264=IEA, GO:0015629=IEA, GO:0051291=IEA, GO:0007406=IEA, GO:0005829=TAS, GO:0042692=TAS, GO:0043297=IEA, GO:0005915=IEA, GO:0045880=IEA, GO:0071681=IDA, GO:0001541=IEA, GO:0051015=IEA, GO:0014704=IEA, GO:0005911=IDA, GO:0042475=IEA, GO:0007155=IEA, GO:0043066=IEA, GO:0045296=IEA, GO:0045295=IPI, GO:0001669=IEA, GO:0034329=TAS, GO:0007568=IEA, GO:0045216=TAS, GO:0030027=IEA, GO:0051149=TAS, GO:0007163=IEA, GO:0005198=IEA, GO:0017166=IPI, GO:0008584=IEA, GO:0034332=TAS} adherens junction organization, aging, apical junction assembly, axon regeneration, cell adhesion, cell junction assembly, cell-cell junction organization, cellular response to indole-3-methanol, establishment or maintenance of cell polarity, gap junction assembly, male gonad development, muscle cell differentiation, negative regulation of apoptotic process, negative regulation of neuroblast proliferation, odontogenesis of dentin-containing tooth, ovarian follicle development, positive regulation of muscle cell differentiation, positive regulation of smoothened signaling pathway, protein heterooligomerization, response to estrogen stimulus acrosomal vesicle, actin cytoskeleton, catenin complex, cell-cell junction, cytosol, intercalated disc, lamellipodium, plasma membrane, zonula adherens actin filament binding, beta-catenin binding, cadherin binding, gamma-catenin binding, protein binding, structural molecule activity, vinculin binding Human Ensembl:ENSRNOP00000008041 CTNNA2 Reactome UniProtKB {GO:0005515=PMID:16182284, GO:0030424=GO_REF:0000024, GO:0045296=GO_REF:0000002, GO:0060134=GO_REF:0000024, GO:0007409=GO_REF:0000024, GO:0021942=GO_REF:0000024, GO:0015629=GO_REF:0000002, GO:0030027=GO_REF:0000019, GO:0005829=Reactome:REACT_21371, GO:0048854=GO_REF:0000024, GO:0042692=Reactome:REACT_21303, GO:0016323=GO_REF:0000019, GO:0048813=GO_REF:0000024, GO:0051823=GO_REF:0000024, GO:0016337=GO_REF:0000024, GO:0005737=PMID:16182284, GO:0051149=Reactome:REACT_21402, GO:0005913=GO_REF:0000019, GO:0005912=GO_REF:0000024, GO:0005198=GO_REF:0000002, GO:0005200=PMID:8432524, GO:0007155=GO_REF:0000002} P26232 Catenin alpha-2 protein 20130301 {GO:0005515=IPI, GO:0030424=ISS, GO:0045296=IEA, GO:0060134=ISS, GO:0007409=ISS, GO:0021942=ISS, GO:0015629=IEA, GO:0030027=IEA, GO:0005829=TAS, GO:0048854=ISS, GO:0042692=TAS, GO:0016323=IEA, GO:0048813=ISS, GO:0051823=ISS, GO:0016337=ISS, GO:0005737=IDA, GO:0051149=TAS, GO:0005913=IEA, GO:0005912=ISS, GO:0005198=IEA, GO:0005200=NAS, GO:0007155=IEA} axonogenesis, brain morphogenesis, cell adhesion, cell-cell adhesion, dendrite morphogenesis, muscle cell differentiation, positive regulation of muscle cell differentiation, prepulse inhibition, radial glia guided migration of Purkinje cell, regulation of synapse structural plasticity actin cytoskeleton, adherens junction, axon, basolateral plasma membrane, cell-cell adherens junction, cytoplasm, cytosol, lamellipodium cadherin binding, protein binding, structural constituent of cytoskeleton, structural molecule activity Human CTNNA3 IntAct UniProtKB {GO:0005916=PMID:11590244, GO:0005515=PMID:22190034, GO:0005737=GO_REF:0000037, GO:0016337=PMID:11590244, GO:0045296=PMID:11590244, GO:0005198=GO_REF:0000002, GO:0007155=GO_REF:0000002, GO:0015629=GO_REF:0000002, GO:0030027=GO_REF:0000019} Q9UI47 Catenin alpha-3 protein 20130415 {GO:0005916=IDA, GO:0005515=IPI, GO:0005737=IEA, GO:0016337=IPI, GO:0045296=TAS, GO:0005198=IEA, GO:0007155=IEA, GO:0015629=IEA, GO:0030027=IEA} cell adhesion, cell-cell adhesion actin cytoskeleton, cytoplasm, fascia adherens, lamellipodium cadherin binding, protein binding, structural molecule activity Human UniProtKB:P04591:PRO_0000038596 CTNNAL1 MGI UniProtKB {GO:0045296=GO_REF:0000002, GO:0005886=GO_REF:0000039, GO:0005198=GO_REF:0000002, GO:0007266=PMID:12270917, GO:0015629=GO_REF:0000002, GO:0007155=GO_REF:0000002, GO:0005829=PMID:12270917} Q9UBT7 Alpha-catulin protein 20091021 {GO:0045296=IEA, GO:0005886=IEA, GO:0005198=IEA, GO:0007266=IDA, GO:0015629=IEA, GO:0007155=IEA, GO:0005829=IDA} Rho protein signal transduction, cell adhesion actin cytoskeleton, cytosol, plasma membrane cadherin binding, structural molecule activity Human CTNNB1 BHF-UCL UniProtKB {GO:0005515=PMID:18287330, GO:0030057=GO_REF:0000033, GO:0043627=GO_REF:0000019, GO:0030054=PMID:19038973, GO:0003700=GO_REF:0000019, GO:0072033=GO_REF:0000033, GO:0044212=PMID:18579517, GO:0045453=GO_REF:0000019, GO:0030877=PMID:16188939, GO:0016342=PMID:20302655, GO:0031528=GO_REF:0000033, GO:0046332=PMID:18593713, GO:0072182=GO_REF:0000024, GO:0048599=GO_REF:0000033, GO:2000008=PMID:19996314, GO:0001711=GO_REF:0000033, GO:0031069=GO_REF:0000033, GO:0060916=GO_REF:0000033, GO:0016337=PMID:18593713, GO:0042129=GO_REF:0000033, GO:0045445=GO_REF:0000019, GO:0016055=PMID:10644691, GO:0001102=PMID:19443654, GO:0071664=GO_REF:0000019, GO:0005813=PMID:20300119, GO:0001708=GO_REF:0000019, GO:0045743=GO_REF:0000033, GO:0003713=PMID:11751639, GO:0001701=GO_REF:0000019, GO:0001702=GO_REF:0000033, GO:0044325=PMID:19996314, GO:0001889=GO_REF:0000033, GO:0000922=GO_REF:0000039, GO:0060440=GO_REF:0000033, GO:0051149=Reactome:REACT_21402, GO:0060441=GO_REF:0000019, GO:0061154=PMID:20123964, GO:0003136=GO_REF:0000033, GO:0043588=GO_REF:0000019, GO:0043587=GO_REF:0000033, GO:0046686=GO_REF:0000019, GO:0008134=PMID:20123964, GO:0051145=GO_REF:0000033, GO:0035315=PMID:19251162, GO:0048471=PMID:19038973, GO:0060066=GO_REF:0000019, GO:0035112=GO_REF:0000019, GO:0044336=PMID:12154096, GO:0048145=PMID:16858403, GO:0005634=PMID:9707618, GO:0001837=PMID:14679171, GO:0051291=GO_REF:0000019, GO:0044334=PMID:17072303, GO:0005829=Reactome:REACT_21371, GO:0014010=GO_REF:0000033, GO:0005916=GO_REF:0000033, GO:0005915=GO_REF:0000033, GO:0043296=GO_REF:0000019, GO:0005913=PMID:20086044, GO:0005912=PMID:16858403, GO:0002089=GO_REF:0000019, GO:0005911=PMID:19996314, GO:0042475=GO_REF:0000033, GO:0048469=GO_REF:0000019, GO:0004871=PMID:10192393, GO:0033234=PMID:22155184, GO:0060070=PMID:19187541, GO:0007016=GO_REF:0000033, GO:0022009=GO_REF:0000033, GO:0003266=GO_REF:0000019, GO:0001569=PMID:20123964, GO:0042493=PMID:18291362, GO:2000017=GO_REF:0000019, GO:0060742=GO_REF:0000019, GO:0045671=GO_REF:0000033, GO:0048660=PMID:17122440, GO:0007398=GO_REF:0000033, GO:0045669=GO_REF:0000033, GO:0003337=GO_REF:0000033, GO:0071363=PMID:16858403, GO:0016020=GO_REF:0000024, GO:0005198=GO_REF:0000033, GO:0034394=PMID:20086044, GO:0007494=GO_REF:0000019, GO:0035116=GO_REF:0000019, GO:0048262=GO_REF:0000033, GO:0030900=GO_REF:0000019, GO:0035115=GO_REF:0000019, GO:0001764=GO_REF:0000019, GO:0030902=GO_REF:0000033, GO:0030018=GO_REF:0000033, GO:0001658=GO_REF:0000033, GO:0045202=GO_REF:0000033, GO:0034750=GO_REF:0000019, GO:0048538=GO_REF:0000033, GO:0050681=PMID:15572661, GO:0072079=GO_REF:0000033, GO:0032403=GO_REF:0000019, GO:0010909=PMID:15853773, GO:0042692=Reactome:REACT_21303, GO:0030539=GO_REF:0000033, GO:0000578=GO_REF:0000033, GO:0003690=GO_REF:0000019, GO:0032993=PMID:10825188, GO:0061047=GO_REF:0000033, GO:0060479=GO_REF:0000033, GO:0043123=GO_REF:0000033, GO:0005938=PMID:19038973, GO:0032355=PMID:15304487, GO:0070602=PMID:20300119, GO:0033077=GO_REF:0000033, GO:0045296=PMID:18287330, GO:0019901=GO_REF:0000033, GO:0045294=PMID:7890674, GO:0019903=PMID:16574648, GO:0030331=PMID:15304487, GO:0048489=GO_REF:0000033, GO:0000122=GO_REF:0000033, GO:0060769=GO_REF:0000033, GO:0001840=GO_REF:0000019, GO:0030027=GO_REF:0000033, GO:0030997=PMID:18086858, GO:0050808=GO_REF:0000033, GO:0009898=GO_REF:0000033, GO:0060484=GO_REF:0000033, GO:0005924=PMID:20399743, GO:0019899=PMID:18356165, GO:0045893=PMID:18787224, GO:0061324=GO_REF:0000024, GO:0061198=GO_REF:0000019, GO:0045892=PMID:19653274, GO:0045603=GO_REF:0000019, GO:0042733=GO_REF:0000019, GO:0008285=PMID:12970740, GO:0005886=GO_REF:0000052, GO:0034333=PMID:20123964, GO:0072054=GO_REF:0000033, GO:0035257=PMID:12799378, GO:0009954=GO_REF:0000033, GO:0030326=GO_REF:0000033, GO:0072053=GO_REF:0000033, GO:0006921=Reactome:REACT_995, GO:0009950=GO_REF:0000033, GO:0071944=PMID:19038973, GO:0036023=GO_REF:0000024, GO:0071681=PMID:10868478, GO:0016323=GO_REF:0000019, GO:0005737=PMID:9707618, GO:0009948=GO_REF:0000019, GO:0043198=GO_REF:0000033, GO:0045944=PMID:15592430, GO:0070491=GO_REF:0000019, GO:0060492=GO_REF:0000033, GO:0031641=GO_REF:0000019, GO:0032331=GO_REF:0000033, GO:0007155=PMID:19101069, GO:0019900=PMID:8638126, GO:0034097=GO_REF:0000019, GO:0005667=PMID:11751639, GO:0043066=PMID:18787224, GO:0043065=PMID:12970740, GO:0035050=GO_REF:0000019, GO:0090279=PMID:19996314, GO:0030316=GO_REF:0000019, GO:0045765=PMID:18756595, GO:0070411=PMID:18593713, GO:0006915=Reactome:REACT_578, GO:0045177=GO_REF:0000019, GO:0002052=GO_REF:0000019, GO:0070412=PMID:20097766, GO:0060789=GO_REF:0000033, GO:0002053=GO_REF:0000019, GO:0008022=PMID:15843474, GO:0016328=PMID:12072559, GO:0006351=GO_REF:0000037, GO:0071407=GO_REF:0000019, GO:0070369=PMID:9065401, GO:0031016=GO_REF:0000033, GO:0007160=GO_REF:0000033, GO:0035255=GO_REF:0000019, GO:0003682=GO_REF:0000019, GO:0007403=GO_REF:0000033, GO:0048715=GO_REF:0000019, GO:0048617=GO_REF:0000033, GO:0034613=GO_REF:0000019, GO:0043410=GO_REF:0000033, GO:0030521=PMID:15572661} P35222 Catenin beta-1 protein 20100825 {GO:0005515=IPI, GO:0030057=IBA, GO:0043627=IEA, GO:0030054=IDA, GO:0003700=IEA, GO:0072033=IBA, GO:0044212=IDA, GO:0045453=IEA, GO:0030877=IDA, GO:0016342=IDA, GO:0031528=IBA, GO:0046332=IPI, GO:0072182=ISS, GO:0048599=IBA, GO:2000008=IDA, GO:0001711=IBA, GO:0031069=IBA, GO:0060916=IBA, GO:0016337=IMP, GO:0042129=IBA, GO:0045445=IEA, GO:0016055=IDA, GO:0001102=IPI, GO:0071664=IEA, GO:0005813=IDA, GO:0001708=IEA, GO:0045743=IBA, GO:0003713=IDA, GO:0001701=IEA, GO:0001702=IBA, GO:0044325=IPI, GO:0001889=IBA, GO:0000922=IEA, GO:0060440=IBA, GO:0051149=TAS, GO:0060441=IEA, GO:0061154=IMP, GO:0003136=IBA, GO:0043588=IEA, GO:0043587=IBA, GO:0046686=IEA, GO:0008134=IPI, GO:0051145=IBA, GO:0035315=TAS, GO:0048471=IDA, GO:0060066=IEA, GO:0035112=IEA, GO:0044336=IMP, GO:0048145=TAS, GO:0005634=IDA, GO:0001837=TAS, GO:0051291=IEA, GO:0044334=IMP, GO:0005829=TAS, GO:0014010=IBA, GO:0005916=IBA, GO:0005915=IBA, GO:0043296=IEA, GO:0005913=IDA, GO:0005912=IDA, GO:0002089=IEA, GO:0005911=IDA, GO:0042475=IBA, GO:0048469=IEA, GO:0004871=NAS, GO:0033234=IDA, GO:0060070=IDA, GO:0007016=IBA, GO:0022009=IBA, GO:0003266=IEA, GO:0001569=IC, GO:0042493=IEP, GO:2000017=IEA, GO:0060742=IEA, GO:0045671=IBA, GO:0048660=IMP, GO:0007398=IBA, GO:0045669=IBA, GO:0003337=IBA, GO:0071363=IMP, GO:0016020=ISS, GO:0005198=IBA, GO:0034394=IMP, GO:0007494=IEA, GO:0035116=IEA, GO:0048262=IBA, GO:0030900=IEA, GO:0035115=IEA, GO:0001764=IEA, GO:0030902=IBA, GO:0030018=IBA, GO:0001658=IBA, GO:0045202=IBA, GO:0034750=IEA, GO:0048538=IBA, GO:0050681=NAS, GO:0072079=IBA, GO:0032403=IEA, GO:0010909=IMP, GO:0042692=TAS, GO:0030539=IBA, GO:0000578=IBA, GO:0003690=IEA, GO:0032993=IDA, GO:0061047=IBA, GO:0060479=IBA, GO:0043123=IBA, GO:0005938=IDA, GO:0032355=IDA, GO:0070602=IMP, GO:0033077=IBA, GO:0045296=IPI, GO:0019901=IBA, GO:0045294=IPI, GO:0019903=IPI, GO:0030331=IPI, GO:0048489=IBA, GO:0000122=IBA, GO:0060769=IBA, GO:0001840=IEA, GO:0030027=IBA, GO:0030997=IDA, GO:0050808=IBA, GO:0009898=IBA, GO:0060484=IBA, GO:0005924=IDA, GO:0019899=IPI, GO:0045893=IDA, GO:0061324=ISS, GO:0061198=IEA, GO:0045892=IMP, GO:0045603=IEA, GO:0042733=IEA, GO:0008285=IDA, GO:0005886=IDA, GO:0034333=IMP, GO:0072054=IBA, GO:0035257=IPI, GO:0009954=IBA, GO:0030326=IBA, GO:0072053=IBA, GO:0006921=TAS, GO:0009950=IBA, GO:0071944=IDA, GO:0036023=ISS, GO:0071681=IDA, GO:0016323=IEA, GO:0005737=IDA, GO:0009948=IEA, GO:0043198=IBA, GO:0045944=IMP, GO:0070491=IEA, GO:0060492=IBA, GO:0031641=IEA, GO:0032331=IBA, GO:0007155=IMP, GO:0019900=IPI, GO:0034097=IEA, GO:0005667=IDA, GO:0043066=IMP, GO:0043065=IDA, GO:0035050=IEA, GO:0090279=IDA, GO:0030316=IEA, GO:0045765=TAS, GO:0070411=IPI, GO:0006915=TAS, GO:0045177=IEA, GO:0002052=IEA, GO:0070412=IPI, GO:0060789=IBA, GO:0002053=IEA, GO:0008022=IPI, GO:0016328=IDA, GO:0006351=IEA, GO:0071407=IEA, GO:0070369=IDA, GO:0031016=IBA, GO:0007160=IBA, GO:0035255=IEA, GO:0003682=IEA, GO:0007403=IBA, GO:0048715=IEA, GO:0048617=IBA, GO:0034613=IEA, GO:0043410=IBA, GO:0030521=NAS} Schwann cell proliferation, T cell differentiation in thymus, Wnt receptor signaling pathway, adherens junction assembly, androgen receptor signaling pathway, anterior/posterior axis specification, apoptotic process, bone resorption, branching involved in ureteric bud morphogenesis, canonical Wnt receptor signaling pathway, canonical Wnt receptor signaling pathway involved in negative regulation of apoptotic process, canonical Wnt receptor signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation, canonical Wnt receptor signaling pathway involved in positive regulation of epithelial to mesenchymal transition, cell adhesion, cell fate specification, cell maturation, cell-cell adhesion, cell-matrix adhesion, cellular component disassembly involved in execution phase of apoptosis, cellular protein localization, cellular response to growth factor stimulus, cellular response to indole-3-methanol, cellular response to organic cyclic compound, central nervous system vasculogenesis, cytoskeletal anchoring at plasma membrane, determination of dorsal/ventral asymmetry, dorsal/ventral axis specification, ectoderm development, embryonic axis specification, embryonic digit morphogenesis, embryonic foregut morphogenesis, embryonic forelimb morphogenesis, embryonic heart tube development, embryonic hindlimb morphogenesis, embryonic limb morphogenesis, embryonic skeletal limb joint morphogenesis, endodermal cell fate commitment, endothelial tube morphogenesis, epithelial cell differentiation involved in prostate gland development, epithelial to mesenchymal transition, epithelial tube branching involved in lung morphogenesis, forebrain development, fungiform papilla formation, gastrulation with mouth forming second, genitalia morphogenesis, glial cell fate determination, hair cell differentiation, hair follicle morphogenesis, hair follicle placode formation, hindbrain development, in utero embryonic development, lens morphogenesis in camera-type eye, liver development, lung cell differentiation, lung induction, lung-associated mesenchyme development, male genitalia development, mesenchymal cell proliferation involved in lung development, mesenchymal to epithelial transition involved in metanephros morphogenesis, midgut development, muscle cell differentiation, myoblast differentiation, negative regulation of apoptotic process, negative regulation of cell proliferation, negative regulation of chondrocyte differentiation, negative regulation of heart induction by canonical Wnt receptor signaling pathway, negative regulation of oligodendrocyte differentiation, negative regulation of osteoclast differentiation, negative regulation of protein sumoylation, negative regulation of transcription from RNA polymerase II promoter, negative regulation of transcription, DNA-dependent, nephron tubule formation, neural plate development, neuron migration, odontogenesis of dentin-containing tooth, oocyte development, osteoclast differentiation, oviduct development, pancreas development, patterning of blood vessels, positive regulation of I-kappaB kinase/NF-kappaB cascade, positive regulation of MAPK cascade, positive regulation of apoptotic process, positive regulation of branching involved in lung morphogenesis, positive regulation of determination of dorsal identity, positive regulation of endothelial cell differentiation, positive regulation of epithelial cell proliferation involved in prostate gland development, positive regulation of fibroblast growth factor receptor signaling pathway, positive regulation of heparan sulfate proteoglycan biosynthetic process, positive regulation of mesenchymal cell proliferation, positive regulation of muscle cell differentiation, positive regulation of neuroblast proliferation, positive regulation of osteoblast differentiation, positive regulation of transcription from RNA polymerase II promoter, positive regulation of transcription, DNA-dependent, protein heterooligomerization, protein localization to cell surface, proximal/distal pattern formation, regulation of T cell proliferation, regulation of angiogenesis, regulation of calcium ion import, regulation of centriole-centriole cohesion, regulation of centromeric sister chromatid cohesion, regulation of fibroblast proliferation, regulation of myelination, regulation of nephron tubule epithelial cell differentiation, regulation of protein localization to cell surface, regulation of secondary heart field cardioblast proliferation, regulation of smooth muscle cell proliferation, renal inner medulla development, renal outer medulla development, renal vesicle formation, response to cadmium ion, response to cytokine stimulus, response to drug, response to estradiol stimulus, response to estrogen stimulus, skin development, smooth muscle cell differentiation, synapse organization, synaptic vesicle transport, thymus development, tongue morphogenesis, trachea formation, transcription, DNA-dependent Scrib-APC-beta-catenin complex, Z disc, adherens junction, apical junction complex, apical part of cell, basolateral plasma membrane, beta-catenin destruction complex, beta-catenin-TCF7L2 complex, catenin complex, catenin-TCF7L2 complex, cell cortex, cell junction, cell periphery, cell-cell adherens junction, cell-cell junction, cell-substrate adherens junction, centrosome, cytoplasm, cytosol, dendritic shaft, desmosome, fascia adherens, internal side of plasma membrane, lamellipodium, lateral plasma membrane, membrane, microvillus membrane, nucleus, perinuclear region of cytoplasm, plasma membrane, protein-DNA complex, spindle pole, synapse, transcription factor complex, zonula adherens I-SMAD binding, R-SMAD binding, RNA polymerase II activating transcription factor binding, SMAD binding, alpha-catenin binding, androgen receptor binding, cadherin binding, chromatin binding, double-stranded DNA binding, enzyme binding, estrogen receptor binding, ion channel binding, ionotropic glutamate receptor binding, kinase binding, nuclear hormone receptor binding, protein C-terminus binding, protein binding, protein complex binding, protein kinase binding, protein phosphatase binding, repressing transcription factor binding, sequence-specific DNA binding transcription factor activity, signal transducer activity, structural molecule activity, transcription coactivator activity, transcription factor binding, transcription regulatory region DNA binding Human CTNNBIP1 BHF-UCL UniProtKB {GO:0002528=PMID:18287330, GO:0005515=PMID:21885566, GO:0032091=PMID:18287330, GO:0072201=PMID:18977368, GO:0001658=GO_REF:0000033, GO:0008013=PMID:18287330, GO:0030178=GO_REF:0000033, GO:0030877=PMID:16188939, GO:0005634=PMID:19569129, GO:0048662=GO_REF:0000019, GO:0000122=GO_REF:0000019, GO:0009952=GO_REF:0000033, GO:0043433=PMID:18977368, GO:0005829=PMID:18287330, GO:0043392=GO_REF:0000019, GO:0045669=PMID:18977368, GO:0060633=GO_REF:0000019, GO:0005737=PMID:19569129, GO:0045657=PMID:19569129, GO:0016055=GO_REF:0000019, GO:0070016=PMID:12408825} Q9NSA3 Beta-catenin-interacting protein 1 protein 20100722 {GO:0002528=IMP, GO:0005515=IPI, GO:0032091=IDA, GO:0072201=IMP, GO:0001658=IBA, GO:0008013=IPI, GO:0030178=IBA, GO:0030877=IDA, GO:0005634=IDA, GO:0048662=IEA, GO:0000122=IEA, GO:0009952=IBA, GO:0043433=IMP, GO:0005829=IDA, GO:0043392=IEA, GO:0045669=IMP, GO:0060633=IEA, GO:0005737=IDA, GO:0045657=IMP, GO:0016055=IEA, GO:0070016=IPI} Wnt receptor signaling pathway, anterior/posterior pattern specification, branching involved in ureteric bud morphogenesis, negative regulation of DNA binding, negative regulation of Wnt receptor signaling pathway, negative regulation of mesenchymal cell proliferation, negative regulation of protein binding, negative regulation of sequence-specific DNA binding transcription factor activity, negative regulation of smooth muscle cell proliferation, negative regulation of transcription from RNA polymerase II promoter, negative regulation of transcription initiation from RNA polymerase II promoter, positive regulation of monocyte differentiation, positive regulation of osteoblast differentiation, regulation of vascular permeability involved in acute inflammatory response beta-catenin destruction complex, cytoplasm, cytosol, nucleus armadillo repeat domain binding, beta-catenin binding, protein binding Human CTNNBL1 HPA UniProtKB {GO:0000974=PMID:15175653, GO:0005515=PMID:20176811, GO:0008380=GO_REF:0000037, GO:0006397=GO_REF:0000037, GO:0043065=PMID:12659813, GO:0005730=GO_REF:0000052, GO:0006915=GO_REF:0000037, GO:0005681=PMID:20176811, GO:0016445=PMID:18722174, GO:0005634=GO_REF:0000052, GO:0019899=PMID:18722174} Q8WYA6 Beta-catenin-like protein 1 protein 20080818 {GO:0000974=IDA, GO:0005515=IPI, GO:0008380=IEA, GO:0006397=IEA, GO:0043065=IDA, GO:0005730=IDA, GO:0006915=IEA, GO:0005681=IDA, GO:0016445=IMP, GO:0005634=IDA, GO:0019899=IPI} RNA splicing, apoptotic process, mRNA processing, positive regulation of apoptotic process, somatic diversification of immunoglobulins Prp19 complex, nucleolus, nucleus, spliceosomal complex enzyme binding, protein binding NOT Human CTNND1 BHF-UCL UniProtKB {GO:0005515=PMID:20123964, GO:0060690=GO_REF:0000019, GO:0005886=PMID:20123964, GO:0005634=PMID:20123964, GO:0001738=GO_REF:0000019, GO:0005829=PMID:20123964, GO:0016337=GO_REF:0000019, GO:0005737=PMID:17047063, GO:0005913=GO_REF:0000019, GO:0005911=PMID:12370829, GO:0016055=GO_REF:0000037, GO:0007155=PMID:8808291, GO:0090090=PMID:20123964, GO:0007435=GO_REF:0000019, GO:0006355=GO_REF:0000037, GO:0045296=PMID:12734196, GO:0019903=GO_REF:0000019, GO:0034329=Reactome:REACT_20676, GO:0019904=GO_REF:0000019, GO:0005102=PMID:19332538, GO:0030496=PMID:15166316, GO:0006351=GO_REF:0000037, GO:0030027=GO_REF:0000019, GO:0045216=Reactome:REACT_19331, GO:0030216=GO_REF:0000019, GO:0034332=Reactome:REACT_19195} O60716 Catenin delta-1 protein 20100721 {GO:0005515=IPI, GO:0060690=IEA, GO:0005886=IMP, GO:0005634=IDA, GO:0001738=IEA, GO:0005829=IMP, GO:0016337=IEA, GO:0005737=IDA, GO:0005913=IEA, GO:0005911=IDA, GO:0016055=IEA, GO:0007155=NAS, GO:0090090=IMP, GO:0007435=IEA, GO:0006355=IEA, GO:0045296=IPI, GO:0019903=IEA, GO:0034329=TAS, GO:0019904=IEA, GO:0005102=IPI, GO:0030496=IDA, GO:0006351=IEA, GO:0030027=IEA, GO:0045216=TAS, GO:0030216=IEA, GO:0034332=TAS} Wnt receptor signaling pathway, adherens junction organization, cell adhesion, cell junction assembly, cell-cell adhesion, cell-cell junction organization, epithelial cell differentiation involved in salivary gland development, keratinocyte differentiation, morphogenesis of a polarized epithelium, negative regulation of canonical Wnt receptor signaling pathway, regulation of transcription, DNA-dependent, salivary gland morphogenesis, transcription, DNA-dependent cell-cell adherens junction, cell-cell junction, cytoplasm, cytosol, lamellipodium, midbody, nucleus, plasma membrane cadherin binding, protein binding, protein domain specific binding, protein phosphatase binding, receptor binding Human CTNND2 PINC UniProtKB {GO:0005515=PMID:19706687, GO:0006355=GO_REF:0000037, GO:0007275=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0006351=GO_REF:0000037, GO:0007165=PMID:9223106, GO:0005737=PMID:9342840, GO:0005912=GO_REF:0000039, GO:0048167=GO_REF:0000019, GO:0043204=GO_REF:0000039, GO:0007612=GO_REF:0000019, GO:0007155=PMID:9223106, GO:0001763=GO_REF:0000019, GO:0007158=GO_REF:0000029} Q9UQB3 Catenin delta-2 protein 20050308 {GO:0005515=IPI, GO:0006355=IEA, GO:0007275=IEA, GO:0005634=IEA, GO:0006351=IEA, GO:0007165=TAS, GO:0005737=TAS, GO:0005912=IEA, GO:0048167=IEA, GO:0043204=IEA, GO:0007612=IEA, GO:0007155=TAS, GO:0001763=IEA, GO:0007158=NAS} cell adhesion, learning, morphogenesis of a branching structure, multicellular organismal development, neuron cell-cell adhesion, regulation of synaptic plasticity, regulation of transcription, DNA-dependent, signal transduction, transcription, DNA-dependent adherens junction, cytoplasm, nucleus, perikaryon protein binding Human CTPS2 Reactome UniProtKB {GO:0005739=GO_REF:0000019, GO:0015949=Reactome:REACT_21330, GO:0055086=Reactome:REACT_1698, GO:0006221=GO_REF:0000002, GO:0044281=Reactome:REACT_111217, GO:0006220=PMID:10899599, GO:0044210=GO_REF:0000041, GO:0005524=GO_REF:0000037, GO:0003883=Reactome:REACT_21305, GO:0005829=Reactome:REACT_21305, GO:0006541=GO_REF:0000037} Q9NRF8 CTP synthase 2 protein 20130213 {GO:0005739=IEA, GO:0015949=TAS, GO:0055086=TAS, GO:0006221=IEA, GO:0044281=TAS, GO:0006220=TAS, GO:0044210=IEA, GO:0005524=IEA, GO:0003883=EXP, GO:0005829=TAS, GO:0006541=IEA} 'de novo' CTP biosynthetic process, glutamine metabolic process, nucleobase-containing small molecule interconversion, nucleobase-containing small molecule metabolic process, pyrimidine nucleotide biosynthetic process, pyrimidine nucleotide metabolic process, small molecule metabolic process cytosol, mitochondrion ATP binding, CTP synthase activity Human CTR9 IntAct UniProtKB {GO:0005515=PMID:20541477, GO:0033523=PMID:16307923, GO:0080182=PMID:16024656, GO:0035327=GO_REF:0000024, GO:0000122=GO_REF:0000024, GO:0007259=GO_REF:0000024, GO:0001711=GO_REF:0000024, GO:0006351=GO_REF:0000037, GO:0071222=GO_REF:0000024, GO:0051571=PMID:16024656, GO:0016607=GO_REF:0000039, GO:0045638=PMID:20541477, GO:0045944=PMID:20178742, GO:0019827=PMID:19345177, GO:0032968=PMID:20178742, GO:2001162=PMID:16024656, GO:0016593=PMID:20178742, GO:0070102=GO_REF:0000024, GO:0016055=GO_REF:0000037, GO:0042169=GO_REF:0000019, GO:0010390=PMID:16307923} Q6PD62 RNA polymerase-associated protein CTR9 homolog protein 20130415 {GO:0005515=IPI, GO:0033523=IDA, GO:0080182=IMP, GO:0035327=ISS, GO:0000122=ISS, GO:0007259=ISS, GO:0001711=ISS, GO:0006351=IEA, GO:0071222=ISS, GO:0051571=IMP, GO:0016607=IEA, GO:0045638=IDA, GO:0045944=IDA, GO:0019827=IDA, GO:0032968=IDA, GO:2001162=IMP, GO:0016593=IDA, GO:0070102=ISS, GO:0016055=IEA, GO:0042169=IEA, GO:0010390=IDA} JAK-STAT cascade, Wnt receptor signaling pathway, cellular response to lipopolysaccharide, endodermal cell fate commitment, histone H2B ubiquitination, histone H3-K4 trimethylation, histone monoubiquitination, interleukin-6-mediated signaling pathway, negative regulation of myeloid cell differentiation, negative regulation of transcription from RNA polymerase II promoter, positive regulation of histone H3-K4 methylation, positive regulation of histone H3-K79 methylation, positive regulation of transcription elongation from RNA polymerase II promoter, positive regulation of transcription from RNA polymerase II promoter, stem cell maintenance, transcription, DNA-dependent Cdc73/Paf1 complex, nuclear speck, transcriptionally active chromatin SH2 domain binding, protein binding Human UniProtKB:Q03164 CTRB1 Reactome UniProtKB {GO:0022617=Reactome:REACT_118572, GO:0004252=PMID:2917002, GO:0030198=Reactome:REACT_118779, GO:0007586=GO_REF:0000037, GO:0006508=GO_REF:0000029, GO:0005576=Reactome:REACT_118776, GO:0005615=GO_REF:0000039} P17538 Chymotrypsinogen B protein 20130213 {GO:0022617=TAS, GO:0004252=NAS, GO:0030198=TAS, GO:0007586=IEA, GO:0006508=NAS, GO:0005576=TAS, GO:0005615=IEA} digestion, extracellular matrix disassembly, extracellular matrix organization, proteolysis extracellular region, extracellular space serine-type endopeptidase activity Human CTRC PINC UniProtKB {GO:0004252=GO_REF:0000002, GO:0006508=GO_REF:0000037, GO:0008233=PMID:8635596} Q99895 Chymotrypsin-C protein 20030904 {GO:0004252=IEA, GO:0006508=IEA, GO:0008233=TAS} proteolysis peptidase activity, serine-type endopeptidase activity Human CTRL PINC UniProtKB {GO:0004252=GO_REF:0000002, GO:0007586=PMID:9065485, GO:0006508=GO_REF:0000019, GO:0005615=PMID:9065485} P40313 Chymotrypsin-like protease CTRL-1 protein 20030904 {GO:0004252=IEA, GO:0007586=TAS, GO:0006508=IEA, GO:0005615=TAS} digestion, proteolysis extracellular space serine-type endopeptidase activity Human CTSA InterPro UniProtKB {GO:0006665=Reactome:REACT_19323, GO:0006687=Reactome:REACT_116105, GO:0005783=PMID:1387645, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0044281=Reactome:REACT_111217, GO:0043085=PMID:3107551, GO:0005764=PMID:3136930, GO:0006886=PMID:1387645, GO:0043231=GO_REF:0000052, GO:0005739=GO_REF:0000019, GO:0004185=GO_REF:0000002, GO:0006508=GO_REF:0000002, GO:0004180=PMID:2244901, GO:0008047=PMID:3107551, GO:0043202=Reactome:REACT_116118} Q5JZH0 Lysosomal protective protein 20 kDa chain protein 20130413 {GO:0006665=TAS, GO:0006687=TAS, GO:0005783=TAS, GO:0005730=IDA, GO:0005634=IDA, GO:0044281=TAS, GO:0043085=TAS, GO:0005764=NAS, GO:0006886=TAS, GO:0043231=IDA, GO:0005739=IEA, GO:0004185=IEA, GO:0006508=IEA, GO:0004180=TAS, GO:0008047=TAS, GO:0043202=TAS} glycosphingolipid metabolic process, intracellular protein transport, positive regulation of catalytic activity, proteolysis, small molecule metabolic process, sphingolipid metabolic process endoplasmic reticulum, intracellular membrane-bounded organelle, lysosomal lumen, lysosome, mitochondrion, nucleolus, nucleus carboxypeptidase activity, enzyme activator activity, serine-type carboxypeptidase activity Human InterPro:IPR001563|InterPro:IPR018202 CTSB HPA UniProtKB {GO:0005515=PMID:6203523, GO:0042470=GO_REF:0000039, GO:0048471=PMID:15614436, GO:0005730=GO_REF:0000052, GO:0005576=Reactome:REACT_150437, GO:0042981=PMID:16130169, GO:0002224=Reactome:REACT_6966, GO:0005615=PMID:22261194, GO:0005764=GO_REF:0000019, GO:0043231=GO_REF:0000052, GO:0004197=PMID:6203523, GO:0005739=GO_REF:0000019, GO:0005622=PMID:1645961, GO:0050790=GO_REF:0000002, GO:0022617=Reactome:REACT_118572, GO:0030198=Reactome:REACT_118779, GO:0045087=Reactome:REACT_6802, GO:0036021=Reactome:REACT_118824, GO:0030574=Reactome:REACT_150401, GO:0006508=PMID:7890620, GO:0008233=PMID:7890620} P07858 Cathepsin B protein 20120912 {GO:0005515=IPI, GO:0042470=IEA, GO:0048471=IDA, GO:0005730=IDA, GO:0005576=TAS, GO:0042981=TAS, GO:0002224=TAS, GO:0005615=ISS, GO:0005764=IEA, GO:0043231=IDA, GO:0004197=IDA, GO:0005739=IEA, GO:0005622=TAS, GO:0050790=IEA, GO:0022617=TAS, GO:0030198=TAS, GO:0045087=TAS, GO:0036021=TAS, GO:0030574=TAS, GO:0006508=IDA, GO:0008233=IDA} collagen catabolic process, extracellular matrix disassembly, extracellular matrix organization, innate immune response, proteolysis, regulation of apoptotic process, regulation of catalytic activity, toll-like receptor signaling pathway endolysosome lumen, extracellular region, extracellular space, intracellular, intracellular membrane-bounded organelle, lysosome, melanosome, mitochondrion, nucleolus, perinuclear region of cytoplasm cysteine-type endopeptidase activity, peptidase activity, protein binding Human CTSC PINC UniProtKB {GO:0031404=GO_REF:0000019, GO:0005794=GO_REF:0000019, GO:0010033=GO_REF:0000019, GO:0004252=GO_REF:0000019, GO:0005783=GO_REF:0000019, GO:0007568=GO_REF:0000019, GO:0043621=GO_REF:0000019, GO:0005764=PMID:7665576, GO:0042802=GO_REF:0000019, GO:0006955=PMID:9092576, GO:0001913=GO_REF:0000019, GO:0006508=GO_REF:0000002, GO:0008234=GO_REF:0000002} P53634 Dipeptidyl peptidase 1 protein 20030904 {GO:0031404=IEA, GO:0005794=IEA, GO:0010033=IEA, GO:0004252=IEA, GO:0005783=IEA, GO:0007568=IEA, GO:0043621=IEA, GO:0005764=TAS, GO:0042802=IEA, GO:0006955=TAS, GO:0001913=IEA, GO:0006508=IEA, GO:0008234=IEA} T cell mediated cytotoxicity, aging, immune response, proteolysis, response to organic substance Golgi apparatus, endoplasmic reticulum, lysosome chloride ion binding, cysteine-type peptidase activity, identical protein binding, protein self-association, serine-type endopeptidase activity Human CTSD BHF-UCL UniProtKB {GO:0008219=GO_REF:0000037, GO:0042470=GO_REF:0000039, GO:0005576=Reactome:REACT_150386, GO:0005615=PMID:22261194, GO:0005764=PMID:19723497, GO:0005739=GO_REF:0000019, GO:0019886=Reactome:REACT_121399, GO:0022617=Reactome:REACT_118572, GO:0030198=Reactome:REACT_118779, GO:0030574=Reactome:REACT_150401, GO:0006508=GO_REF:0000037, GO:0004190=GO_REF:0000019, GO:0000045=GO_REF:0000019, GO:0043202=Reactome:REACT_121107} P07339 Cathepsin D protein 20120228 {GO:0008219=IEA, GO:0042470=IEA, GO:0005576=TAS, GO:0005615=ISS, GO:0005764=IDA, GO:0005739=IEA, GO:0019886=TAS, GO:0022617=TAS, GO:0030198=TAS, GO:0030574=TAS, GO:0006508=IEA, GO:0004190=IEA, GO:0000045=IEA, GO:0043202=TAS} antigen processing and presentation of exogenous peptide antigen via MHC class II, autophagic vacuole assembly, cell death, collagen catabolic process, extracellular matrix disassembly, extracellular matrix organization, proteolysis extracellular region, extracellular space, lysosomal lumen, lysosome, melanosome, mitochondrion aspartic-type endopeptidase activity Human UniProtKB:P00795 CTSE PINC UniProtKB {GO:0019886=PMID:8765029, GO:0016540=GO_REF:0000019, GO:0007586=PMID:2674141, GO:0006508=GO_REF:0000037, GO:0004190=PMID:7789521, GO:0042803=GO_REF:0000019, GO:0005768=PMID:7983070} P14091 Cathepsin E protein 20030904 {GO:0019886=IDA, GO:0016540=IEA, GO:0007586=TAS, GO:0006508=IEA, GO:0004190=IDA, GO:0042803=IEA, GO:0005768=IDA} antigen processing and presentation of exogenous peptide antigen via MHC class II, digestion, protein autoprocessing, proteolysis endosome aspartic-type endopeptidase activity, protein homodimerization activity Human CTSF Reactome UniProtKB {GO:0004197=PMID:9822672, GO:0019886=Reactome:REACT_121399, GO:0006508=GO_REF:0000037, GO:0008234=GO_REF:0000002, GO:0005764=PMID:9822672, GO:0043202=Reactome:REACT_121107} Q9UBX1 Cathepsin F protein 20110201 {GO:0004197=TAS, GO:0019886=TAS, GO:0006508=IEA, GO:0008234=IEA, GO:0005764=TAS, GO:0043202=TAS} antigen processing and presentation of exogenous peptide antigen via MHC class II, proteolysis lysosomal lumen, lysosome cysteine-type endopeptidase activity, cysteine-type peptidase activity Human CTSG Reactome UniProtKB {GO:0002003=Reactome:REACT_147707, GO:0009986=GO_REF:0000039, GO:0005886=Reactome:REACT_147744, GO:0004252=PMID:8194606, GO:0050832=GO_REF:0000019, GO:0005576=Reactome:REACT_118608, GO:0006955=PMID:2569462, GO:0022617=Reactome:REACT_118572, GO:0030198=Reactome:REACT_118779, GO:0050778=GO_REF:0000019, GO:0032496=GO_REF:0000019, GO:0006508=PMID:11907569, GO:0008233=PMID:11907569, GO:0044130=GO_REF:0000019, GO:0030141=PMID:11907569, GO:0044267=Reactome:REACT_17015, GO:0008201=PMID:11907569, GO:0070946=GO_REF:0000019} P08311 Cathepsin G protein 20130301 {GO:0002003=TAS, GO:0009986=IEA, GO:0005886=TAS, GO:0004252=IDA, GO:0050832=IEA, GO:0005576=TAS, GO:0006955=TAS, GO:0022617=TAS, GO:0030198=TAS, GO:0050778=IEA, GO:0032496=IEA, GO:0006508=IDA, GO:0008233=IDA, GO:0044130=IEA, GO:0030141=IDA, GO:0044267=TAS, GO:0008201=IDA, GO:0070946=IEA} angiotensin maturation, cellular protein metabolic process, defense response to fungus, extracellular matrix disassembly, extracellular matrix organization, immune response, negative regulation of growth of symbiont in host, neutrophil mediated killing of gram-positive bacterium, positive regulation of immune response, proteolysis, response to lipopolysaccharide cell surface, extracellular region, plasma membrane, secretory granule heparin binding, peptidase activity, serine-type endopeptidase activity Human CTSH BHF-UCL UniProtKB {GO:0001656=GO_REF:0000024, GO:0005515=PMID:6203523, GO:0030984=GO_REF:0000019, GO:0008284=GO_REF:0000024, GO:0097067=GO_REF:0000019, GO:0004252=GO_REF:0000024, GO:0010813=PMID:15127951, GO:0010815=PMID:15127951, GO:0007283=GO_REF:0000019, GO:0043621=GO_REF:0000019, GO:0070324=PMID:21217776, GO:0005615=PMID:9050938, GO:0032403=GO_REF:0000019, GO:0031648=PMID:17500053, GO:0019882=PMID:15196205, GO:0033619=GO_REF:0000019, GO:0006508=PMID:6203523, GO:0043129=PMID:18216060, GO:0032526=GO_REF:0000024, GO:0070371=PMID:21217776, GO:0030108=PMID:16822283, GO:0043066=GO_REF:0000024, GO:0001669=GO_REF:0000019, GO:0001520=GO_REF:0000019, GO:0045766=GO_REF:0000024, GO:0002250=PMID:15196205, GO:0004197=PMID:6203523, GO:0010952=PMID:20435891, GO:0016505=PMID:20435891, GO:0004175=PMID:14766755, GO:0001913=GO_REF:0000024, GO:0002764=PMID:16822283, GO:0004177=GO_REF:0000019, GO:0008233=PMID:18216060, GO:0060448=GO_REF:0000024, GO:0010634=GO_REF:0000024, GO:0031638=GO_REF:0000019} P09668 Pro-cathepsin H protein 20080810 {GO:0001656=ISS, GO:0005515=IPI, GO:0030984=IEA, GO:0008284=ISS, GO:0097067=IEA, GO:0004252=ISS, GO:0010813=IDA, GO:0010815=IDA, GO:0007283=IEA, GO:0043621=IEA, GO:0070324=IDA, GO:0005615=IDA, GO:0032403=IEA, GO:0031648=IMP, GO:0019882=TAS, GO:0033619=IEA, GO:0006508=IDA, GO:0043129=IDA, GO:0032526=ISS, GO:0070371=IDA, GO:0030108=IDA, GO:0043066=ISS, GO:0001669=IEA, GO:0001520=IEA, GO:0045766=ISS, GO:0002250=IEP, GO:0004197=IDA, GO:0010952=IDA, GO:0016505=IDA, GO:0004175=IDA, GO:0001913=ISS, GO:0002764=IDA, GO:0004177=IEA, GO:0008233=IDA, GO:0060448=ISS, GO:0010634=ISS, GO:0031638=IEA} ERK1 and ERK2 cascade, T cell mediated cytotoxicity, adaptive immune response, antigen processing and presentation, bradykinin catabolic process, cellular response to thyroid hormone stimulus, dichotomous subdivision of terminal units involved in lung branching, immune response-regulating signaling pathway, membrane protein proteolysis, metanephros development, negative regulation of apoptotic process, neuropeptide catabolic process, positive regulation of angiogenesis, positive regulation of cell proliferation, positive regulation of epithelial cell migration, positive regulation of peptidase activity, protein destabilization, proteolysis, response to retinoic acid, spermatogenesis, surfactant homeostasis, zymogen activation acrosomal vesicle, extracellular space, outer dense fiber HLA-A specific activating MHC class I receptor activity, aminopeptidase activity, apoptotic protease activator activity, cysteine-type endopeptidase activity, endopeptidase activity, kininogen binding, peptidase activity, protein binding, protein complex binding, protein self-association, serine-type endopeptidase activity, thyroid hormone binding Human UniProtKB:P01034 CTSK InterPro UniProtKB {GO:0045453=GO_REF:0000019, GO:0005576=Reactome:REACT_150437, GO:0002224=Reactome:REACT_6966, GO:0005615=GO_REF:0000019, GO:0004197=PMID:9143502, GO:0001957=GO_REF:0000019, GO:0022617=Reactome:REACT_118572, GO:0030198=Reactome:REACT_118779, GO:0036021=Reactome:REACT_118824, GO:0045087=Reactome:REACT_6802, GO:0030574=Reactome:REACT_150401, GO:0006508=GO_REF:0000002, GO:0008234=GO_REF:0000002} Q5QP40 Cathepsin K protein 20130413 {GO:0045453=IEA, GO:0005576=TAS, GO:0002224=TAS, GO:0005615=IEA, GO:0004197=TAS, GO:0001957=IEA, GO:0022617=TAS, GO:0030198=TAS, GO:0036021=TAS, GO:0045087=TAS, GO:0030574=TAS, GO:0006508=IEA, GO:0008234=IEA} bone resorption, collagen catabolic process, extracellular matrix disassembly, extracellular matrix organization, innate immune response, intramembranous ossification, proteolysis, toll-like receptor signaling pathway endolysosome lumen, extracellular region, extracellular space cysteine-type endopeptidase activity, cysteine-type peptidase activity Human InterPro:IPR000668|InterPro:IPR013128|InterPro:IPR015644 CTSL1 InterPro UniProtKB {GO:0005515=PMID:17889653, GO:0005634=PMID:21326229, GO:0005576=Reactome:REACT_150437, GO:0002224=Reactome:REACT_6966, GO:0005764=GO_REF:0000029, GO:0071888=PMID:18495127, GO:0002250=PMID:15196205, GO:0004197=PMID:14511383, GO:0042393=PMID:21326229, GO:0019886=Reactome:REACT_121399, GO:0022617=Reactome:REACT_118572, GO:0019882=PMID:15196205, GO:0030198=Reactome:REACT_118779, GO:0036021=Reactome:REACT_118824, GO:0045087=Reactome:REACT_6802, GO:0030574=Reactome:REACT_150401, GO:0006508=GO_REF:0000002, GO:0008234=GO_REF:0000002, GO:0043202=Reactome:REACT_121107} Q5T8F0 Cathepsin L1 light chain protein 20130413 {GO:0005515=IPI, GO:0005634=TAS, GO:0005576=TAS, GO:0002224=TAS, GO:0005764=NAS, GO:0071888=NAS, GO:0002250=IEP, GO:0004197=IDA, GO:0042393=IDA, GO:0019886=TAS, GO:0022617=TAS, GO:0019882=TAS, GO:0030198=TAS, GO:0036021=TAS, GO:0045087=TAS, GO:0030574=TAS, GO:0006508=IEA, GO:0008234=IEA, GO:0043202=TAS} adaptive immune response, antigen processing and presentation, antigen processing and presentation of exogenous peptide antigen via MHC class II, collagen catabolic process, extracellular matrix disassembly, extracellular matrix organization, innate immune response, macrophage apoptotic process, proteolysis, toll-like receptor signaling pathway endolysosome lumen, extracellular region, lysosomal lumen, lysosome, nucleus cysteine-type endopeptidase activity, cysteine-type peptidase activity, histone binding, protein binding Human InterPro:IPR000668|InterPro:IPR013128 CTSL2 Reactome UniProtKB {GO:0030984=GO_REF:0000019, GO:0043005=GO_REF:0000019, GO:0048102=GO_REF:0000019, GO:0021675=GO_REF:0000019, GO:0010259=GO_REF:0000019, GO:0007283=GO_REF:0000019, GO:0032403=GO_REF:0000019, GO:0046697=GO_REF:0000019, GO:0019886=Reactome:REACT_121399, GO:0060008=GO_REF:0000019, GO:0022617=Reactome:REACT_118572, GO:0030198=Reactome:REACT_118779, GO:0006508=GO_REF:0000019, GO:0043204=GO_REF:0000019, GO:0043202=Reactome:REACT_121107, GO:0009267=GO_REF:0000019, GO:0042277=GO_REF:0000019, GO:0051384=GO_REF:0000019, GO:0005576=Reactome:REACT_118765, GO:0034698=GO_REF:0000019, GO:0009749=GO_REF:0000019, GO:0004197=GO_REF:0000019, GO:0005902=GO_REF:0000019, GO:0004177=GO_REF:0000019, GO:0008234=PMID:9563472, GO:0009897=GO_REF:0000019} O60911 Cathepsin L2 protein 20110201 {GO:0030984=IEA, GO:0043005=IEA, GO:0048102=IEA, GO:0021675=IEA, GO:0010259=IEA, GO:0007283=IEA, GO:0032403=IEA, GO:0046697=IEA, GO:0019886=TAS, GO:0060008=IEA, GO:0022617=TAS, GO:0030198=TAS, GO:0006508=IEA, GO:0043204=IEA, GO:0043202=TAS, GO:0009267=IEA, GO:0042277=IEA, GO:0051384=IEA, GO:0005576=TAS, GO:0034698=IEA, GO:0009749=IEA, GO:0004197=IEA, GO:0005902=IEA, GO:0004177=IEA, GO:0008234=TAS, GO:0009897=IEA} Sertoli cell differentiation, antigen processing and presentation of exogenous peptide antigen via MHC class II, autophagic cell death, cellular response to starvation, decidualization, extracellular matrix disassembly, extracellular matrix organization, multicellular organismal aging, nerve development, proteolysis, response to glucocorticoid stimulus, response to glucose stimulus, response to gonadotropin stimulus, spermatogenesis external side of plasma membrane, extracellular region, lysosomal lumen, microvillus, neuron projection, perikaryon aminopeptidase activity, cysteine-type endopeptidase activity, cysteine-type peptidase activity, kininogen binding, peptide binding, protein complex binding Human CTSO PINC UniProtKB {GO:0004197=PMID:7929457, GO:0006508=GO_REF:0000037, GO:0005764=GO_REF:0000039} P43234 Cathepsin O protein 20030904 {GO:0004197=TAS, GO:0006508=IEA, GO:0005764=IEA} proteolysis lysosome cysteine-type endopeptidase activity Human CTSS HPA UniProtKB {GO:0002474=Reactome:REACT_75820, GO:0002480=Reactome:REACT_111168, GO:0042590=Reactome:REACT_111119, GO:0005576=PMID:14718574, GO:0002224=Reactome:REACT_6966, GO:0005764=GO_REF:0000029, GO:0043231=GO_REF:0000052, GO:0002250=PMID:15196205, GO:0004197=PMID:1373132, GO:0019886=Reactome:REACT_121399, GO:0006955=PMID:8157683, GO:0016020=GO_REF:0000019, GO:0019882=PMID:15196205, GO:0045087=Reactome:REACT_6802, GO:0036021=Reactome:REACT_118824, GO:0006508=GO_REF:0000019, GO:0043202=Reactome:REACT_121306} P25774 Cathepsin S protein 20101115 {GO:0002474=TAS, GO:0002480=TAS, GO:0042590=TAS, GO:0005576=NAS, GO:0002224=TAS, GO:0005764=NAS, GO:0043231=IDA, GO:0002250=IEP, GO:0004197=TAS, GO:0019886=TAS, GO:0006955=TAS, GO:0016020=IEA, GO:0019882=TAS, GO:0045087=TAS, GO:0036021=TAS, GO:0006508=IEA, GO:0043202=TAS} adaptive immune response, antigen processing and presentation, antigen processing and presentation of exogenous peptide antigen via MHC class I, antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent, antigen processing and presentation of exogenous peptide antigen via MHC class II, antigen processing and presentation of peptide antigen via MHC class I, immune response, innate immune response, proteolysis, toll-like receptor signaling pathway endolysosome lumen, extracellular region, intracellular membrane-bounded organelle, lysosomal lumen, lysosome, membrane cysteine-type endopeptidase activity Human CTSW PINC UniProtKB {GO:0006955=PMID:9823953, GO:0006508=GO_REF:0000037, GO:0008234=GO_REF:0000037} P56202 Cathepsin W protein 20030904 {GO:0006955=TAS, GO:0006508=IEA, GO:0008234=IEA} immune response, proteolysis cysteine-type peptidase activity Human CTSZ Reactome UniProtKB {GO:0060441=GO_REF:0000019, GO:0005886=Reactome:REACT_147799, GO:0002003=Reactome:REACT_147707, GO:0005783=GO_REF:0000054, GO:0006508=GO_REF:0000037, GO:0008234=GO_REF:0000037, GO:0044267=Reactome:REACT_17015, GO:0005764=GO_REF:0000039} Q9UBR2 Cathepsin Z protein 20130301 {GO:0060441=IEA, GO:0005886=TAS, GO:0002003=TAS, GO:0005783=IDA, GO:0006508=IEA, GO:0008234=IEA, GO:0044267=TAS, GO:0005764=IEA} angiotensin maturation, cellular protein metabolic process, epithelial tube branching involved in lung morphogenesis, proteolysis endoplasmic reticulum, lysosome, plasma membrane cysteine-type peptidase activity Human CTTN BHF-UCL UniProtKB {GO:0005515=PMID:19146815, GO:0005737=PMID:10760273, GO:0043197=GO_REF:0000039, GO:0005856=GO_REF:0000039, GO:0005938=GO_REF:0000024, GO:0001726=GO_REF:0000024, GO:0030027=PMID:10760273} Q14247 Src substrate cortactin protein 20110112 {GO:0005515=IPI, GO:0005737=IDA, GO:0043197=IEA, GO:0005856=IEA, GO:0005938=ISS, GO:0001726=ISS, GO:0030027=IDA} cell cortex, cytoplasm, cytoskeleton, dendritic spine, lamellipodium, ruffle protein binding Human CTTNBP2 UniProtKB UniProtKB {GO:0017124=GO_REF:0000019, GO:0043197=GO_REF:0000039, GO:0007420=GO_REF:0000019, GO:0005938=GO_REF:0000039, GO:0008021=GO_REF:0000019} Q8WZ74 Cortactin-binding protein 2 protein 20130413 {GO:0017124=IEA, GO:0043197=IEA, GO:0007420=IEA, GO:0005938=IEA, GO:0008021=IEA} brain development cell cortex, dendritic spine, synaptic vesicle SH3 domain binding Human UniProtKB-SubCell:SL-0284 CTTNBP2NL IntAct UniProtKB {GO:0005515=PMID:23455922, GO:0005737=GO_REF:0000037, GO:0015629=GO_REF:0000054} Q9P2B4 CTTNBP2 N-terminal-like protein protein 20130415 {GO:0005515=IPI, GO:0005737=IEA, GO:0015629=IDA} actin cytoskeleton, cytoplasm protein binding Human UniProtKB:Q9Y6E0 CTU1 UniProtKB UniProtKB {GO:0005515=PMID:19017811, GO:0002098=PMID:19017811, GO:0005739=GO_REF:0000019, GO:0000049=GO_REF:0000037, GO:0034227=PMID:19017811, GO:0005524=GO_REF:0000002, GO:0016740=GO_REF:0000037, GO:0005829=GO_REF:0000024} Q7Z7A3 Cytoplasmic tRNA 2-thiolation protein 1 protein 20090529 {GO:0005515=IPI, GO:0002098=NAS, GO:0005739=IEA, GO:0000049=IEA, GO:0034227=NAS, GO:0005524=IEA, GO:0016740=IEA, GO:0005829=ISS} tRNA thio-modification, tRNA wobble uridine modification cytosol, mitochondrion ATP binding, protein binding, tRNA binding, transferase activity Human UniProtKB:P53088 CTU2 HPA UniProtKB {GO:0005739=GO_REF:0000052, GO:0005515=PMID:19017811, GO:0002098=PMID:19017811, GO:0043234=PMID:19017811, GO:0005737=GO_REF:0000052, GO:0034227=PMID:19017811, GO:0008033=GO_REF:0000038} Q2VPK5 Cytoplasmic tRNA 2-thiolation protein 2 protein 20111111 {GO:0005739=IDA, GO:0005515=IPI, GO:0002098=NAS, GO:0043234=IDA, GO:0005737=IDA, GO:0034227=NAS, GO:0008033=IEA} tRNA processing, tRNA thio-modification, tRNA wobble uridine modification cytoplasm, mitochondrion, protein complex protein binding Human CTXN1 UniProtKB UniProtKB {GO:0016021=GO_REF:0000037} P60606 Cortexin-1 protein 20130413 {GO:0016021=IEA} integral to membrane Human UniProtKB-KW:KW-0812 CUBN Reactome UniProtKB {GO:0006629=Reactome:REACT_602, GO:0005215=PMID:9478979, GO:0015889=PMID:10080186, GO:0005886=Reactome:REACT_13688, GO:0005783=GO_REF:0000019, GO:0030139=GO_REF:0000019, GO:0044281=Reactome:REACT_111217, GO:0031526=PMID:11994745, GO:0005765=GO_REF:0000039, GO:0042803=PMID:10552972, GO:0005829=Reactome:REACT_13608, GO:0042953=GO_REF:0000019, GO:0016324=GO_REF:0000019, GO:0001894=PMID:11994745, GO:0004872=PMID:10080186, GO:0008202=Reactome:REACT_11057, GO:0043202=Reactome:REACT_13664, GO:0008203=GO_REF:0000037, GO:0005794=GO_REF:0000019, GO:0031419=GO_REF:0000037, GO:0042359=Reactome:REACT_13523, GO:0005509=GO_REF:0000002, GO:0031232=PMID:11994745, GO:0006898=PMID:11994745, GO:0005905=GO_REF:0000019, GO:0016020=PMID:9478979, GO:0042157=Reactome:REACT_13621, GO:0010008=GO_REF:0000039} O60494 Cubilin protein 20080410 {GO:0006629=TAS, GO:0005215=TAS, GO:0015889=TAS, GO:0005886=TAS, GO:0005783=IEA, GO:0030139=IEA, GO:0044281=TAS, GO:0031526=NAS, GO:0005765=IEA, GO:0042803=IDA, GO:0005829=TAS, GO:0042953=IEA, GO:0016324=IEA, GO:0001894=NAS, GO:0004872=TAS, GO:0008202=TAS, GO:0043202=TAS, GO:0008203=IEA, GO:0005794=IEA, GO:0031419=IEA, GO:0042359=TAS, GO:0005509=IEA, GO:0031232=NAS, GO:0006898=NAS, GO:0005905=IEA, GO:0016020=TAS, GO:0042157=TAS, GO:0010008=IEA} cholesterol metabolic process, cobalamin transport, lipid metabolic process, lipoprotein metabolic process, lipoprotein transport, receptor-mediated endocytosis, small molecule metabolic process, steroid metabolic process, tissue homeostasis, vitamin D metabolic process Golgi apparatus, apical plasma membrane, brush border membrane, coated pit, cytosol, endocytic vesicle, endoplasmic reticulum, endosome membrane, extrinsic to external side of plasma membrane, lysosomal lumen, lysosomal membrane, membrane, plasma membrane calcium ion binding, cobalamin binding, protein homodimerization activity, receptor activity, transporter activity Human CUEDC1 null null {} null null null null {} null null null CUEDC2 HPA UniProtKB {GO:0005515=PMID:17347654, GO:0005737=GO_REF:0000052, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052} Q9H467 CUE domain-containing protein 2 protein 20110516 {GO:0005515=IPI, GO:0005737=IDA, GO:0005730=IDA, GO:0005634=IDA} cytoplasm, nucleolus, nucleus protein binding Human CUL1 IntAct UniProtKB {GO:0005515=PMID:20708156, GO:0031461=PMID:22405651, GO:0006513=GO_REF:0000019, GO:0016567=PMID:15103331, GO:0008285=PMID:8681378, GO:0008283=GO_REF:0000019, GO:0051437=Reactome:REACT_6821, GO:0031146=GO_REF:0000024, GO:0031145=Reactome:REACT_6828, GO:0051439=Reactome:REACT_6837, GO:0097193=PMID:8681378, GO:0005829=Reactome:REACT_118856, GO:0000084=Reactome:REACT_899, GO:0000082=Reactome:REACT_1783, GO:0007219=Reactome:REACT_118859, GO:0019048=GO_REF:0000037, GO:0009887=GO_REF:0000019, GO:0005654=Reactome:REACT_160209, GO:0007050=PMID:8681378, GO:0000278=Reactome:REACT_152, GO:0000080=Reactome:REACT_1590, GO:0031625=GO_REF:0000002, GO:0019005=PMID:23263282} Q13616 Cullin-1 protein 20130415 {GO:0005515=IPI, GO:0031461=IDA, GO:0006513=IEA, GO:0016567=IDA, GO:0008285=TAS, GO:0008283=IEA, GO:0051437=TAS, GO:0031146=ISS, GO:0031145=TAS, GO:0051439=TAS, GO:0097193=TAS, GO:0005829=TAS, GO:0000084=TAS, GO:0000082=TAS, GO:0007219=TAS, GO:0019048=IEA, GO:0009887=IEA, GO:0005654=TAS, GO:0007050=TAS, GO:0000278=TAS, GO:0000080=TAS, GO:0031625=IEA, GO:0019005=IDA} G1 phase of mitotic cell cycle, G1/S transition of mitotic cell cycle, Notch signaling pathway, S phase of mitotic cell cycle, SCF-dependent proteasomal ubiquitin-dependent protein catabolic process, anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process, cell cycle arrest, cell proliferation, intrinsic apoptotic signaling pathway, mitotic cell cycle, negative regulation of cell proliferation, organ morphogenesis, positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle, protein monoubiquitination, protein ubiquitination, regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle, virus-host interaction SCF ubiquitin ligase complex, cullin-RING ubiquitin ligase complex, cytosol, nucleoplasm protein binding, ubiquitin protein ligase binding Human UniProtKB:Q00987 CUL2 InterPro UniProtKB {GO:0005515=PMID:22190034, GO:0031461=GO_REF:0000002, GO:0006511=GO_REF:0000002, GO:0016567=GO_REF:0000041, GO:0008285=PMID:8681378, GO:0071456=Reactome:REACT_121311, GO:0061418=Reactome:REACT_120815, GO:0033554=Reactome:REACT_120956, GO:0097193=PMID:8681378, GO:0005829=Reactome:REACT_121002, GO:0000082=PMID:8681378, GO:0019048=GO_REF:0000037, GO:0031462=PMID:17636018, GO:0007050=PMID:8681378, GO:0005654=Reactome:REACT_121374, GO:0031625=GO_REF:0000002} Q5T2B7 Cullin-2 protein 20130413 {GO:0005515=IPI, GO:0031461=IEA, GO:0006511=IEA, GO:0016567=IEA, GO:0008285=TAS, GO:0071456=TAS, GO:0061418=TAS, GO:0033554=TAS, GO:0097193=TAS, GO:0005829=TAS, GO:0000082=TAS, GO:0019048=IEA, GO:0031462=IDA, GO:0007050=TAS, GO:0005654=TAS, GO:0031625=IEA} G1/S transition of mitotic cell cycle, cell cycle arrest, cellular response to hypoxia, cellular response to stress, intrinsic apoptotic signaling pathway, negative regulation of cell proliferation, protein ubiquitination, regulation of transcription from RNA polymerase II promoter in response to hypoxia, ubiquitin-dependent protein catabolic process, virus-host interaction Cul2-RING ubiquitin ligase complex, cullin-RING ubiquitin ligase complex, cytosol, nucleoplasm protein binding, ubiquitin protein ligase binding Human InterPro:IPR001373|InterPro:IPR016157|InterPro:IPR016158|InterPro:IPR019559 CUL3 IntAct UniProtKB {GO:0031208=PMID:19261606, GO:0005515=PMID:22939624, GO:0001831=GO_REF:0000019, GO:0031461=GO_REF:0000002, GO:0006511=GO_REF:0000002, GO:0005827=PMID:19995937, GO:0008284=PMID:9733711, GO:0004842=PMID:19261606, GO:0016567=PMID:19782033, GO:0007369=GO_REF:0000019, GO:0006513=PMID:22358839, GO:0035024=PMID:19782033, GO:0017145=GO_REF:0000024, GO:0043149=PMID:19782033, GO:0005634=GO_REF:0000039, GO:0048208=PMID:22358839, GO:0000910=PMID:19995937, GO:0000082=PMID:8681378, GO:0008054=PMID:10500095, GO:0040016=GO_REF:0000024, GO:0007050=PMID:8681378, GO:0016055=GO_REF:0000019, GO:0031625=GO_REF:0000002, GO:0000209=PMID:19261606, GO:0005794=GO_REF:0000039, GO:0051322=PMID:19995937, GO:0032467=PMID:19261606, GO:0030332=GO_REF:0000019, GO:0097193=PMID:8681378, GO:0006888=PMID:22358839, GO:0016477=PMID:19782033, GO:0007229=GO_REF:0000024, GO:0031463=PMID:19261606, GO:0043161=PMID:19261606, GO:0000090=PMID:17543862} Q13618 Cullin-3 protein 20130415 {GO:0031208=IDA, GO:0005515=IPI, GO:0001831=IEA, GO:0031461=IEA, GO:0006511=IEA, GO:0005827=IDA, GO:0008284=TAS, GO:0004842=IDA, GO:0016567=IDA, GO:0007369=IEA, GO:0006513=IDA, GO:0035024=IMP, GO:0017145=ISS, GO:0043149=IMP, GO:0005634=IEA, GO:0048208=IMP, GO:0000910=IMP, GO:0000082=TAS, GO:0008054=IDA, GO:0040016=ISS, GO:0007050=TAS, GO:0016055=IEA, GO:0031625=IEA, GO:0000209=IDA, GO:0005794=IEA, GO:0051322=IMP, GO:0032467=IMP, GO:0030332=IEA, GO:0097193=TAS, GO:0006888=IDA, GO:0016477=IMP, GO:0007229=ISS, GO:0031463=IDA, GO:0043161=IDA, GO:0000090=IMP} COPII vesicle coating, ER to Golgi vesicle-mediated transport, G1/S transition of mitotic cell cycle, Wnt receptor signaling pathway, anaphase, cell cycle arrest, cell migration, cyclin catabolic process, cytokinesis, embryonic cleavage, gastrulation, integrin-mediated signaling pathway, intrinsic apoptotic signaling pathway, mitotic anaphase, negative regulation of Rho protein signal transduction, positive regulation of cell proliferation, positive regulation of cytokinesis, proteasomal ubiquitin-dependent protein catabolic process, protein monoubiquitination, protein polyubiquitination, protein ubiquitination, stem cell division, stress fiber assembly, trophectodermal cellular morphogenesis, ubiquitin-dependent protein catabolic process Cul3-RING ubiquitin ligase complex, Golgi apparatus, cullin-RING ubiquitin ligase complex, nucleus, polar microtubule POZ domain binding, cyclin binding, protein binding, ubiquitin protein ligase binding, ubiquitin-protein ligase activity Human UniProtKB:P08238 CUL4A PINC UniProtKB {GO:0005515=PMID:12504025, GO:0006511=GO_REF:0000002, GO:0051246=GO_REF:0000019, GO:0016567=GO_REF:0000041, GO:0008285=PMID:8681378, GO:0080008=PMID:18381890, GO:0097193=PMID:8681378, GO:0000082=PMID:8681378, GO:0006281=GO_REF:0000037, GO:0019048=GO_REF:0000037, GO:0045750=GO_REF:0000019, GO:0007050=PMID:8681378, GO:0031464=PMID:20223979, GO:0031625=GO_REF:0000002} Q13619 Cullin-4A protein 20030904 {GO:0005515=IPI, GO:0006511=IEA, GO:0051246=IEA, GO:0016567=IEA, GO:0008285=TAS, GO:0080008=IDA, GO:0097193=TAS, GO:0000082=TAS, GO:0006281=IEA, GO:0019048=IEA, GO:0045750=IEA, GO:0007050=TAS, GO:0031464=IDA, GO:0031625=IEA} DNA repair, G1/S transition of mitotic cell cycle, cell cycle arrest, intrinsic apoptotic signaling pathway, negative regulation of cell proliferation, positive regulation of S phase of mitotic cell cycle, protein ubiquitination, regulation of protein metabolic process, ubiquitin-dependent protein catabolic process, virus-host interaction Cul4-RING ubiquitin ligase complex, Cul4A-RING ubiquitin ligase complex protein binding, ubiquitin protein ligase binding Human CUL4B HPA UniProtKB {GO:0005515=PMID:16964240, GO:0006511=GO_REF:0000002, GO:0031461=GO_REF:0000002, GO:0045732=GO_REF:0000019, GO:0016567=GO_REF:0000041, GO:0005886=GO_REF:0000052, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0007049=PMID:8681378, GO:0006281=GO_REF:0000037, GO:0045750=GO_REF:0000019, GO:0031465=PMID:18794347, GO:0031625=GO_REF:0000002} Q13620 Cullin-4B protein 20101115 {GO:0005515=IPI, GO:0006511=IEA, GO:0031461=IEA, GO:0045732=IEA, GO:0016567=IEA, GO:0005886=IDA, GO:0005730=IDA, GO:0005634=IDA, GO:0007049=NAS, GO:0006281=IEA, GO:0045750=IEA, GO:0031465=IDA, GO:0031625=IEA} DNA repair, cell cycle, positive regulation of S phase of mitotic cell cycle, positive regulation of protein catabolic process, protein ubiquitination, ubiquitin-dependent protein catabolic process Cul4B-RING ubiquitin ligase complex, cullin-RING ubiquitin ligase complex, nucleolus, nucleus, plasma membrane protein binding, ubiquitin protein ligase binding Human CUL5 GOC UniProtKB {GO:0005515=PMID:22190034, GO:0006511=GO_REF:0000002, GO:0031461=GO_REF:0000002, GO:0005262=PMID:9581826, GO:0008285=PMID:8681378, GO:0016567=GO_REF:0000041, GO:0005886=GO_REF:0000019, GO:0008283=PMID:9037604, GO:0051480=GO_REF:0000019, GO:0005634=GO_REF:0000019, GO:0006970=GO_REF:0000019, GO:0097193=PMID:9581826, GO:0005829=Reactome:REACT_115557, GO:0000082=PMID:8681378, GO:0019048=GO_REF:0000037, GO:0070588=PMID:9581826, GO:0016032=Reactome:REACT_6185, GO:0007050=PMID:8681378, GO:0004872=PMID:9581826, GO:0031466=PMID:22405651, GO:0031625=PMID:17636018} Q93034 Cullin-5 protein 20130413 {GO:0005515=IPI, GO:0006511=IEA, GO:0031461=IEA, GO:0005262=TAS, GO:0008285=TAS, GO:0016567=IEA, GO:0005886=IEA, GO:0008283=TAS, GO:0051480=IEA, GO:0005634=IEA, GO:0006970=IEA, GO:0097193=TAS, GO:0005829=TAS, GO:0000082=TAS, GO:0019048=IEA, GO:0070588=TAS, GO:0016032=TAS, GO:0007050=TAS, GO:0004872=TAS, GO:0031466=IDA, GO:0031625=IDA} G1/S transition of mitotic cell cycle, calcium ion transmembrane transport, cell cycle arrest, cell proliferation, cytosolic calcium ion homeostasis, intrinsic apoptotic signaling pathway, negative regulation of cell proliferation, protein ubiquitination, response to osmotic stress, ubiquitin-dependent protein catabolic process, viral reproduction, virus-host interaction Cul5-RING ubiquitin ligase complex, cullin-RING ubiquitin ligase complex, cytosol, nucleus, plasma membrane calcium channel activity, protein binding, receptor activity, ubiquitin protein ligase binding Human CUL7 HPA UniProtKB {GO:0005515=PMID:17298945, GO:0006511=GO_REF:0000002, GO:0048471=GO_REF:0000039, GO:0005794=GO_REF:0000039, GO:0016567=GO_REF:0000041, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0005829=Reactome:REACT_115788, GO:0030968=Reactome:REACT_18356, GO:0005737=GO_REF:0000052, GO:0005680=PMID:12481031, GO:0019048=GO_REF:0000037, GO:0006508=PMID:12481031, GO:0006987=Reactome:REACT_18368, GO:0001570=GO_REF:0000024, GO:0044267=Reactome:REACT_17015, GO:0031625=GO_REF:0000002} Q14999 Cullin-7 protein 20111111 {GO:0005515=IPI, GO:0006511=IEA, GO:0048471=IEA, GO:0005794=IEA, GO:0016567=IEA, GO:0005730=IDA, GO:0005634=IDA, GO:0005829=TAS, GO:0030968=TAS, GO:0005737=IDA, GO:0005680=NAS, GO:0019048=IEA, GO:0006508=NAS, GO:0006987=TAS, GO:0001570=ISS, GO:0044267=TAS, GO:0031625=IEA} activation of signaling protein activity involved in unfolded protein response, cellular protein metabolic process, endoplasmic reticulum unfolded protein response, protein ubiquitination, proteolysis, ubiquitin-dependent protein catabolic process, vasculogenesis, virus-host interaction Golgi apparatus, anaphase-promoting complex, cytoplasm, cytosol, nucleolus, nucleus, perinuclear region of cytoplasm protein binding, ubiquitin protein ligase binding Human CUL9 IntAct UniProtKB {GO:0005515=PMID:18230339, GO:0031461=GO_REF:0000002, GO:0006511=GO_REF:0000002, GO:0005737=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0005524=GO_REF:0000037, GO:0031625=GO_REF:0000002} Q8IWT3 Cullin-9 protein 20130415 {GO:0005515=IPI, GO:0031461=IEA, GO:0006511=IEA, GO:0005737=IEA, GO:0008270=IEA, GO:0005524=IEA, GO:0031625=IEA} ubiquitin-dependent protein catabolic process cullin-RING ubiquitin ligase complex, cytoplasm ATP binding, protein binding, ubiquitin protein ligase binding, zinc ion binding Human UniProtKB:P04637 CUTA IntAct UniProtKB {GO:0005515=PMID:20195357, GO:0008104=PMID:10800960, GO:0016020=PMID:10800960, GO:0010038=GO_REF:0000002, GO:0019899=PMID:10800960} O60888 Protein CutA protein 20130415 {GO:0005515=IPI, GO:0008104=IDA, GO:0016020=IDA, GO:0010038=IEA, GO:0019899=IPI} protein localization, response to metal ion membrane enzyme binding, protein binding Human UniProtKB:P22736 CUTC HPA UniProtKB {GO:0005737=GO_REF:0000052, GO:0051262=PMID:19878721, GO:0055070=PMID:16182249, GO:0016235=GO_REF:0000052, GO:0005507=PMID:19878721, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0006825=PMID:16182249} Q9NTM9 Copper homeostasis protein cutC homolog protein 20110516 {GO:0005737=IDA, GO:0051262=IPI, GO:0055070=NAS, GO:0016235=IDA, GO:0005507=IDA, GO:0005730=IDA, GO:0005634=IDA, GO:0006825=NAS} copper ion homeostasis, copper ion transport, protein tetramerization aggresome, cytoplasm, nucleolus, nucleus copper ion binding Human CUX1 InterPro UniProtKB {GO:0003700=GO_REF:0000002, GO:0042491=GO_REF:0000019, GO:0006357=PMID:1301999, GO:0030324=GO_REF:0000019, GO:0005730=GO_REF:0000052, GO:0006891=GO_REF:0000002, GO:0005634=GO_REF:0000052, GO:0007275=PMID:1301999, GO:0000122=GO_REF:0000019, GO:0006351=GO_REF:0000037, GO:0005829=Reactome:REACT_121382, GO:0043565=GO_REF:0000002, GO:0005737=GO_REF:0000052, GO:0030173=GO_REF:0000002, GO:0000139=GO_REF:0000019, GO:0003682=GO_REF:0000019, GO:0000301=GO_REF:0000019, GO:0030674=GO_REF:0000019} Q13948 Protein CASP protein 20130413 {GO:0003700=IEA, GO:0042491=IEA, GO:0006357=TAS, GO:0030324=IEA, GO:0005730=IDA, GO:0006891=IEA, GO:0005634=IDA, GO:0007275=TAS, GO:0000122=IEA, GO:0006351=IEA, GO:0005829=TAS, GO:0043565=IEA, GO:0005737=IDA, GO:0030173=IEA, GO:0000139=IEA, GO:0003682=IEA, GO:0000301=IEA, GO:0030674=IEA} auditory receptor cell differentiation, intra-Golgi vesicle-mediated transport, lung development, multicellular organismal development, negative regulation of transcription from RNA polymerase II promoter, regulation of transcription from RNA polymerase II promoter, retrograde transport, vesicle recycling within Golgi, transcription, DNA-dependent Golgi membrane, cytoplasm, cytosol, integral to Golgi membrane, nucleolus, nucleus chromatin binding, protein binding, bridging, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity Human InterPro:IPR012955 CUX2 UniProtKB UniProtKB {GO:0043565=GO_REF:0000002, GO:0006355=GO_REF:0000029, GO:0003700=GO_REF:0000029, GO:0071310=GO_REF:0000019, GO:0005634=GO_REF:0000029, GO:0045892=GO_REF:0000019, GO:0006351=GO_REF:0000037} O14529 Homeobox protein cut-like 2 protein 20021104 {GO:0043565=IEA, GO:0006355=NAS, GO:0003700=NAS, GO:0071310=IEA, GO:0005634=NAS, GO:0045892=IEA, GO:0006351=IEA} cellular response to organic substance, negative regulation of transcription, DNA-dependent, regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity Human CUZD1 UniProtKB UniProtKB {GO:0006931=PMID:15184879, GO:0007049=GO_REF:0000037, GO:0042589=GO_REF:0000024, GO:0008283=PMID:15184879, GO:0016021=PMID:15184879, GO:0032023=GO_REF:0000024, GO:0030658=GO_REF:0000039, GO:0051301=GO_REF:0000037} Q86UP6 CUB and zona pellucida-like domain-containing protein 1 protein 20060403 {GO:0006931=NAS, GO:0007049=IEA, GO:0042589=ISS, GO:0008283=NAS, GO:0016021=NAS, GO:0032023=ISS, GO:0030658=IEA, GO:0051301=IEA} cell cycle, cell division, cell proliferation, substrate-dependent cell migration, cell attachment to substrate, trypsinogen activation integral to membrane, transport vesicle membrane, zymogen granule membrane Human CWC15 UniProtKB UniProtKB {GO:0005515=PMID:20176811, GO:0000398=PMID:11991638, GO:0003723=GO_REF:0000024, GO:0005681=PMID:20176811, GO:0005634=PMID:20176811, GO:0071013=PMID:11991638} Q9P013 Spliceosome-associated protein CWC15 homolog protein 20120716 {GO:0005515=IPI, GO:0000398=IC, GO:0003723=ISS, GO:0005681=IDA, GO:0005634=IDA, GO:0071013=IDA} mRNA splicing, via spliceosome catalytic step 2 spliceosome, nucleus, spliceosomal complex RNA binding, protein binding Human CWC22 HPA UniProtKB {GO:0048024=PMID:11991638, GO:0005737=GO_REF:0000052, GO:0016070=GO_REF:0000002, GO:0000398=PMID:11991638, GO:0003723=PMID:11991638, GO:0005730=GO_REF:0000052, GO:0005681=PMID:11991638, GO:0005634=GO_REF:0000052, GO:0071013=PMID:11991638, GO:0003677=GO_REF:0000002} Q9HCG8 Pre-mRNA-splicing factor CWC22 homolog protein 20110516 {GO:0048024=IC, GO:0005737=IDA, GO:0016070=IEA, GO:0000398=IC, GO:0003723=IDA, GO:0005730=IDA, GO:0005681=IDA, GO:0005634=IDA, GO:0071013=IDA, GO:0003677=IEA} RNA metabolic process, mRNA splicing, via spliceosome, regulation of mRNA splicing, via spliceosome catalytic step 2 spliceosome, cytoplasm, nucleolus, nucleus, spliceosomal complex DNA binding, RNA binding Human CWC25 null null {} null null null null {} null null null CWC27 UniProtKB UniProtKB {GO:0000398=PMID:11991638, GO:0006457=GO_REF:0000037, GO:0003755=GO_REF:0000003, GO:0071013=PMID:11991638} Q6UX04 Peptidyl-prolyl cis-trans isomerase CWC27 homolog protein 20110302 {GO:0000398=IC, GO:0006457=IEA, GO:0003755=IEA, GO:0071013=IDA} mRNA splicing, via spliceosome, protein folding catalytic step 2 spliceosome peptidyl-prolyl cis-trans isomerase activity Human CWF19L1 UniProtKB UniProtKB {GO:0008150=GO_REF:0000015, GO:0003674=GO_REF:0000015, GO:0005575=GO_REF:0000015, GO:0003824=GO_REF:0000002} Q69YN2 CWF19-like protein 1 protein 20080829 {GO:0008150=ND, GO:0003674=ND, GO:0005575=ND, GO:0003824=IEA} biological_process cellular_component catalytic activity, molecular_function Human CWF19L2 InterPro UniProtKB {GO:0003824=GO_REF:0000002} Q2TBE0 CWF19-like protein 2 protein 20130413 {GO:0003824=IEA} catalytic activity Human InterPro:IPR011146 CX3CL1 Reactome UniProtKB {GO:0005515=PMID:9931005, GO:0005886=Reactome:REACT_14810, GO:0019221=PMID:11777952, GO:0005615=GO_REF:0000037, GO:0050902=PMID:12714508, GO:0032914=GO_REF:0000019, GO:0051041=PMID:12714508, GO:0006955=PMID:12714508, GO:0006935=PMID:21829356, GO:0007155=GO_REF:0000037, GO:0008009=PMID:21829356, GO:0043066=GO_REF:0000019, GO:0009986=PMID:12714508, GO:0030595=PMID:11777952, GO:0060055=GO_REF:0000019, GO:0030593=GO_REF:0000019, GO:0005102=PMID:12714508, GO:0005576=PMID:12714508, GO:0006952=PMID:12714508, GO:0045766=GO_REF:0000019, GO:0016020=GO_REF:0000002, GO:0050729=PMID:11777952, GO:0048247=GO_REF:0000019, GO:0048246=GO_REF:0000019, GO:0016021=PMID:12714508} P78423 Fractalkine protein 20100217 {GO:0005515=IPI, GO:0005886=TAS, GO:0019221=TAS, GO:0005615=IEA, GO:0050902=TAS, GO:0032914=IEA, GO:0051041=IDA, GO:0006955=TAS, GO:0006935=IDA, GO:0007155=IEA, GO:0008009=IDA, GO:0043066=IEA, GO:0009986=IDA, GO:0030595=TAS, GO:0060055=IEA, GO:0030593=IEA, GO:0005102=TAS, GO:0005576=IDA, GO:0006952=TAS, GO:0045766=IEA, GO:0016020=IEA, GO:0050729=IEP, GO:0048247=IEA, GO:0048246=IEA, GO:0016021=IDA} angiogenesis involved in wound healing, cell adhesion, chemotaxis, cytokine-mediated signaling pathway, defense response, immune response, leukocyte adhesive activation, leukocyte chemotaxis, lymphocyte chemotaxis, macrophage chemotaxis, negative regulation of apoptotic process, neutrophil chemotaxis, positive regulation of angiogenesis, positive regulation of calcium-independent cell-cell adhesion, positive regulation of inflammatory response, positive regulation of transforming growth factor beta1 production cell surface, extracellular region, extracellular space, integral to membrane, membrane, plasma membrane chemokine activity, protein binding, receptor binding Human CX3CR1 GOC UniProtKB {GO:0005515=PMID:9931005, GO:0043005=GO_REF:0000019, GO:0048471=GO_REF:0000019, GO:0005886=Reactome:REACT_14810, GO:0071560=GO_REF:0000019, GO:0007204=GO_REF:0000002, GO:0021795=GO_REF:0000019, GO:0006935=GO_REF:0000002, GO:0004950=PMID:10754298, GO:0002282=GO_REF:0000019, GO:0007155=GO_REF:0000002, GO:0043066=GO_REF:0000019, GO:0030336=GO_REF:0000019, GO:0070098=PMID:10754298, GO:0009611=PMID:10754298, GO:0045766=GO_REF:0000019, GO:0032809=GO_REF:0000019, GO:0006968=PMID:10754298, GO:0071222=GO_REF:0000019, GO:0016495=GO_REF:0000002, GO:0007186=PMID:10754298, GO:0005887=PMID:9390561, GO:0019048=GO_REF:0000037, GO:0016525=GO_REF:0000019, GO:0048246=GO_REF:0000019, GO:0016021=GO_REF:0000038} P49238 CX3C chemokine receptor 1 protein 20130413 {GO:0005515=IPI, GO:0043005=IEA, GO:0048471=IEA, GO:0005886=TAS, GO:0071560=IEA, GO:0007204=IEA, GO:0021795=IEA, GO:0006935=IEA, GO:0004950=TAS, GO:0002282=IEA, GO:0007155=IEA, GO:0043066=IEA, GO:0030336=IEA, GO:0070098=TAS, GO:0009611=TAS, GO:0045766=IEA, GO:0032809=IEA, GO:0006968=TAS, GO:0071222=IEA, GO:0016495=IEA, GO:0007186=TAS, GO:0005887=TAS, GO:0019048=IEA, GO:0016525=IEA, GO:0048246=IEA, GO:0016021=IEA} G-protein coupled receptor signaling pathway, cell adhesion, cellular defense response, cellular response to lipopolysaccharide, cellular response to transforming growth factor beta stimulus, cerebral cortex cell migration, chemokine-mediated signaling pathway, chemotaxis, elevation of cytosolic calcium ion concentration, macrophage chemotaxis, microglial cell activation involved in immune response, negative regulation of angiogenesis, negative regulation of apoptotic process, negative regulation of cell migration, positive regulation of angiogenesis, response to wounding, virus-host interaction integral to membrane, integral to plasma membrane, neuron projection, neuronal cell body membrane, perinuclear region of cytoplasm, plasma membrane C-X3-C chemokine receptor activity, chemokine receptor activity, protein binding Human CXADR HPA UniProtKB {GO:0005515=PMID:11734628, GO:0060044=GO_REF:0000019, GO:0043005=GO_REF:0000024, GO:0030054=GO_REF:0000052, GO:0005886=GO_REF:0000052, GO:0008013=PMID:12297051, GO:0005634=GO_REF:0000052, GO:0030175=GO_REF:0000024, GO:0050900=Reactome:REACT_12051, GO:0030426=GO_REF:0000024, GO:0086067=GO_REF:0000024, GO:0007507=GO_REF:0000024, GO:0016323=PMID:20361046, GO:0010669=PMID:15304526, GO:0005912=PMID:12297051, GO:0014704=GO_REF:0000019, GO:0005911=PMID:20235596, GO:0050839=PMID:15800062, GO:0071253=GO_REF:0000024, GO:0070633=PMID:15800062, GO:0007157=PMID:15800062, GO:0008354=GO_REF:0000024, GO:0031532=PMID:17675666, GO:0001669=GO_REF:0000024, GO:0030593=PMID:15800062, GO:0005730=GO_REF:0000052, GO:0005576=GO_REF:0000039, GO:0030165=PMID:15364909, GO:0045216=GO_REF:0000024, GO:0044297=GO_REF:0000024, GO:0016327=PMID:15364909, GO:0048739=GO_REF:0000024, GO:0043234=PMID:17675666, GO:0007596=Reactome:REACT_604, GO:0005887=PMID:9096397, GO:0019048=GO_REF:0000037, GO:0050776=Reactome:REACT_11152, GO:0045121=PMID:17675666, GO:0007005=GO_REF:0000024, GO:0005923=PMID:15800062} P78310 Coxsackievirus and adenovirus receptor protein 20120912 {GO:0005515=IPI, GO:0060044=IEA, GO:0043005=ISS, GO:0030054=IDA, GO:0005886=IDA, GO:0008013=IPI, GO:0005634=IDA, GO:0030175=ISS, GO:0050900=TAS, GO:0030426=ISS, GO:0086067=ISS, GO:0007507=ISS, GO:0016323=IDA, GO:0010669=IMP, GO:0005912=IDA, GO:0014704=IEA, GO:0005911=IDA, GO:0050839=IPI, GO:0071253=ISS, GO:0070633=IMP, GO:0007157=IDA, GO:0008354=ISS, GO:0031532=IDA, GO:0001669=ISS, GO:0030593=IMP, GO:0005730=IDA, GO:0005576=IEA, GO:0030165=IPI, GO:0045216=ISS, GO:0044297=ISS, GO:0016327=IDA, GO:0048739=ISS, GO:0043234=IDA, GO:0007596=TAS, GO:0005887=NAS, GO:0019048=IEA, GO:0050776=TAS, GO:0045121=IDA, GO:0007005=ISS, GO:0005923=IDA} AV node cell to bundle of His cell communication, actin cytoskeleton reorganization, blood coagulation, cardiac muscle fiber development, cell-cell junction organization, epithelial structure maintenance, germ cell migration, heart development, heterophilic cell-cell adhesion, leukocyte migration, mitochondrion organization, negative regulation of cardiac muscle cell proliferation, neutrophil chemotaxis, regulation of immune response, transepithelial transport, virus-host interaction acrosomal vesicle, adherens junction, apicolateral plasma membrane, basolateral plasma membrane, cell body, cell junction, cell-cell junction, extracellular region, filopodium, growth cone, integral to plasma membrane, intercalated disc, membrane raft, neuron projection, nucleolus, nucleus, plasma membrane, protein complex, tight junction PDZ domain binding, beta-catenin binding, cell adhesion molecule binding, connexin binding, protein binding Human CXCL1 GOC UniProtKB {GO:0008009=GO_REF:0000002, GO:0008285=PMID:9551928, GO:0030036=PMID:9725262, GO:0008283=PMID:8380167, GO:0005102=PMID:9079638, GO:0005576=Reactome:REACT_22289, GO:0043085=PMID:9079638, GO:0005615=GO_REF:0000037, GO:0007399=PMID:9058825, GO:0035556=PMID:9551928, GO:0007165=PMID:9725262, GO:0006955=GO_REF:0000002, GO:0006954=GO_REF:0000037, GO:0006935=PMID:10820279, GO:0007186=PMID:10820279, GO:0008047=PMID:9079638, GO:0008083=GO_REF:0000037} P09341 Growth-regulated alpha protein protein 20130413 {GO:0008009=IEA, GO:0008285=TAS, GO:0030036=TAS, GO:0008283=TAS, GO:0005102=TAS, GO:0005576=TAS, GO:0043085=TAS, GO:0005615=IEA, GO:0007399=TAS, GO:0035556=TAS, GO:0007165=TAS, GO:0006955=IEA, GO:0006954=IEA, GO:0006935=TAS, GO:0007186=TAS, GO:0008047=TAS, GO:0008083=IEA} G-protein coupled receptor signaling pathway, actin cytoskeleton organization, cell proliferation, chemotaxis, immune response, inflammatory response, intracellular signal transduction, negative regulation of cell proliferation, nervous system development, positive regulation of catalytic activity, signal transduction extracellular region, extracellular space chemokine activity, enzyme activator activity, growth factor activity, receptor binding Human CXCL10 BHF-UCL UniProtKB {GO:0008284=GO_REF:0000002, GO:0009306=GO_REF:0000019, GO:0008603=PMID:10903763, GO:0010996=GO_REF:0000019, GO:0008015=PMID:8798675, GO:0009409=GO_REF:0000019, GO:0007267=PMID:3925348, GO:0033280=GO_REF:0000019, GO:0005615=GO_REF:0000019, GO:0034605=GO_REF:0000019, GO:0006955=GO_REF:0000019, GO:0051607=GO_REF:0000019, GO:0006954=GO_REF:0000037, GO:0006935=GO_REF:0000037, GO:0032496=GO_REF:0000019, GO:0010332=GO_REF:0000019, GO:0008009=GO_REF:0000002, GO:0005102=PMID:10201891, GO:0005576=PMID:20041150, GO:0002690=GO_REF:0000019, GO:0007165=PMID:10201891, GO:0007517=PMID:8798675, GO:0016525=GO_REF:0000019, GO:0009897=GO_REF:0000019, GO:0007166=PMID:10903763} P02778 C-X-C motif chemokine 10 protein 20120622 {GO:0008284=IEA, GO:0009306=IEA, GO:0008603=TAS, GO:0010996=IEA, GO:0008015=TAS, GO:0009409=IEA, GO:0007267=TAS, GO:0033280=IEA, GO:0005615=IEA, GO:0034605=IEA, GO:0006955=IEA, GO:0051607=IEA, GO:0006954=IEA, GO:0006935=IEA, GO:0032496=IEA, GO:0010332=IEA, GO:0008009=IEA, GO:0005102=TAS, GO:0005576=IDA, GO:0002690=IEA, GO:0007165=TAS, GO:0007517=TAS, GO:0016525=IEA, GO:0009897=IEA, GO:0007166=TAS} blood circulation, cell surface receptor signaling pathway, cell-cell signaling, cellular response to heat, chemotaxis, defense response to virus, immune response, inflammatory response, muscle organ development, negative regulation of angiogenesis, positive regulation of cell proliferation, positive regulation of leukocyte chemotaxis, protein secretion, response to auditory stimulus, response to cold, response to gamma radiation, response to lipopolysaccharide, response to vitamin D, signal transduction external side of plasma membrane, extracellular region, extracellular space cAMP-dependent protein kinase regulator activity, chemokine activity, receptor binding Human CXCL11 Reactome UniProtKB {GO:0007165=PMID:10233762, GO:0008009=GO_REF:0000019, GO:0006955=GO_REF:0000019, GO:0006954=GO_REF:0000037, GO:0006935=GO_REF:0000037, GO:0007267=PMID:10233762, GO:0005576=Reactome:REACT_22289, GO:0005615=GO_REF:0000037} O14625 C-X-C motif chemokine 11 protein 20080717 {GO:0007165=TAS, GO:0008009=IEA, GO:0006955=IEA, GO:0006954=IEA, GO:0006935=IEA, GO:0007267=TAS, GO:0005576=TAS, GO:0005615=IEA} cell-cell signaling, chemotaxis, immune response, inflammatory response, signal transduction extracellular region, extracellular space chemokine activity Human CXCL12 BHF-UCL UniProtKB {GO:0008015=PMID:10772939, GO:0007281=GO_REF:0000019, GO:0005615=GO_REF:0000037, GO:0006955=GO_REF:0000002, GO:0042098=GO_REF:0000019, GO:0006935=PMID:10620615, GO:0007155=PMID:10198043, GO:0008009=GO_REF:0000019, GO:0043066=PMID:20388803, GO:0008354=GO_REF:0000019, GO:0001569=GO_REF:0000019, GO:0070098=PMID:20388803, GO:0001667=GO_REF:0000019, GO:0005102=PMID:10438529, GO:0006874=PMID:10772939, GO:0005576=Reactome:REACT_115653, GO:0045236=PMID:20388803, GO:0009615=PMID:10772939, GO:0050930=GO_REF:0000019, GO:0007165=PMID:10491003, GO:0008045=GO_REF:0000019, GO:0007186=PMID:8752280, GO:0007420=GO_REF:0000019, GO:0008064=PMID:10570282, GO:2000107=PMID:15059845, GO:0090026=PMID:18802065, GO:0008083=GO_REF:0000037, GO:0009897=GO_REF:0000019} P48061 Stromal cell-derived factor 1 protein 20110708 {GO:0008015=TAS, GO:0007281=IEA, GO:0005615=IEA, GO:0006955=IEA, GO:0042098=IEA, GO:0006935=TAS, GO:0007155=TAS, GO:0008009=IEA, GO:0043066=IDA, GO:0008354=IEA, GO:0001569=IEA, GO:0070098=IDA, GO:0001667=IEA, GO:0005102=TAS, GO:0006874=TAS, GO:0005576=TAS, GO:0045236=IDA, GO:0009615=TAS, GO:0050930=IEA, GO:0007165=TAS, GO:0008045=IEA, GO:0007186=TAS, GO:0007420=IEA, GO:0008064=TAS, GO:2000107=IDA, GO:0090026=IDA, GO:0008083=IEA, GO:0009897=IEA} G-protein coupled receptor signaling pathway, T cell proliferation, ameboidal cell migration, blood circulation, brain development, cell adhesion, cellular calcium ion homeostasis, chemokine-mediated signaling pathway, chemotaxis, germ cell development, germ cell migration, immune response, induction of positive chemotaxis, motor neuron axon guidance, negative regulation of apoptotic process, negative regulation of leukocyte apoptotic process, patterning of blood vessels, positive regulation of monocyte chemotaxis, regulation of actin polymerization or depolymerization, response to virus, signal transduction external side of plasma membrane, extracellular region, extracellular space CXCR chemokine receptor binding, chemokine activity, growth factor activity, receptor binding Human CXCL13 GOC UniProtKB {GO:0035769=GO_REF:0000019, GO:0035768=PMID:11708770, GO:0048248=PMID:11554781, GO:0007267=PMID:11554781, GO:0033625=GO_REF:0000024, GO:0007204=PMID:11554781, GO:0005615=GO_REF:0000037, GO:0002518=GO_REF:0000024, GO:0048535=GO_REF:0000019, GO:0031724=PMID:9463416, GO:0006955=PMID:11554781, GO:0002920=PMID:16531331, GO:0002467=PMID:16543475, GO:0008201=PMID:11708770, GO:0048018=PMID:11554781, GO:0042742=PMID:17562761, GO:0008009=PMID:11554781, GO:0043066=PMID:15580304, GO:0046982=PMID:11708770, GO:0017134=PMID:11708770, GO:0010820=PMID:11554781, GO:0045765=PMID:11708770, GO:2000545=PMID:11708770, GO:0032861=GO_REF:0000024, GO:0005576=PMID:17562761, GO:0002544=PMID:15284119, GO:0033634=GO_REF:0000024, GO:0031735=PMID:10706668, GO:0007165=PMID:11554781, GO:0035754=PMID:9463416} O43927 C-X-C motif chemokine 13 protein 20130413 {GO:0035769=IEA, GO:0035768=IDA, GO:0048248=IPI, GO:0007267=IDA, GO:0033625=ISS, GO:0007204=IDA, GO:0005615=IEA, GO:0002518=ISS, GO:0048535=IEA, GO:0031724=IDA, GO:0006955=IC, GO:0002920=NAS, GO:0002467=NAS, GO:0008201=IDA, GO:0048018=IDA, GO:0042742=IDA, GO:0008009=IDA, GO:0043066=NAS, GO:0046982=IDA, GO:0017134=IDA, GO:0010820=IDA, GO:0045765=NAS, GO:2000545=IDA, GO:0032861=ISS, GO:0005576=IDA, GO:0002544=NAS, GO:0033634=ISS, GO:0031735=IDA, GO:0007165=IDA, GO:0035754=IDA} B cell chemotaxis, B cell chemotaxis across high endothelial venule, activation of Rap GTPase activity, cell-cell signaling, chronic inflammatory response, defense response to bacterium, elevation of cytosolic calcium ion concentration, endothelial cell chemotaxis to fibroblast growth factor, germinal center formation, immune response, lymph node development, lymphocyte chemotaxis across high endothelial venule, negative regulation of apoptotic process, negative regulation of endothelial cell chemotaxis to fibroblast growth factor, positive regulation of T cell chemotaxis, positive regulation of cell-cell adhesion mediated by integrin, positive regulation of integrin activation, regulation of angiogenesis, regulation of humoral immune response, signal transduction extracellular region, extracellular space CCR10 chemokine receptor binding, CXCR3 chemokine receptor binding, CXCR5 chemokine receptor binding, chemokine activity, fibroblast growth factor binding, heparin binding, protein heterodimerization activity, receptor agonist activity Human CXCL14 LIFEdb UniProtKB {GO:0007165=PMID:10049774, GO:0008009=GO_REF:0000002, GO:0048839=GO_REF:0000019, GO:0006955=GO_REF:0000002, GO:0005794=GO_REF:0000054, GO:0006935=GO_REF:0000037, GO:0007267=PMID:10049774, GO:0005615=GO_REF:0000037} O95715 C-X-C motif chemokine 14 protein 20100607 {GO:0007165=TAS, GO:0008009=IEA, GO:0048839=IEA, GO:0006955=IEA, GO:0005794=IDA, GO:0006935=IEA, GO:0007267=TAS, GO:0005615=IEA} cell-cell signaling, chemotaxis, immune response, inner ear development, signal transduction Golgi apparatus, extracellular space chemokine activity Human CXCL16 BHF-UCL UniProtKB {GO:0008009=PMID:18373975, GO:0030335=PMID:18373975, GO:0005886=GO_REF:0000039, GO:0030307=PMID:18373975, GO:0005102=PMID:11017100, GO:0005576=Reactome:REACT_22289, GO:0005615=PMID:18373975, GO:0006898=PMID:11060282, GO:0005041=GO_REF:0000024, GO:0016020=PMID:11060282, GO:0006935=PMID:11290797, GO:0034612=PMID:18373975, GO:0048247=PMID:11017100, GO:0034341=PMID:18373975, GO:0016021=PMID:11017100, GO:0034097=PMID:18373975, GO:0005044=PMID:11060282} Q9H2A7 C-X-C motif chemokine 16 protein 20081119 {GO:0008009=IDA, GO:0030335=IMP, GO:0005886=IEA, GO:0030307=IMP, GO:0005102=NAS, GO:0005576=TAS, GO:0005615=IDA, GO:0006898=NAS, GO:0005041=ISS, GO:0016020=TAS, GO:0006935=NAS, GO:0034612=IDA, GO:0048247=NAS, GO:0034341=IDA, GO:0016021=NAS, GO:0034097=IDA, GO:0005044=TAS} chemotaxis, lymphocyte chemotaxis, positive regulation of cell growth, positive regulation of cell migration, receptor-mediated endocytosis, response to cytokine stimulus, response to interferon-gamma, response to tumor necrosis factor extracellular region, extracellular space, integral to membrane, membrane, plasma membrane chemokine activity, low-density lipoprotein receptor activity, receptor binding, scavenger receptor activity Human CXCL2 BHF-UCL UniProtKB {GO:0008009=GO_REF:0000002, GO:0006955=GO_REF:0000002, GO:0006954=GO_REF:0000037, GO:0006935=GO_REF:0000037, GO:0002237=PMID:19912257, GO:0005576=Reactome:REACT_22289, GO:0005615=GO_REF:0000037} P19875 C-X-C motif chemokine 2 protein 20110202 {GO:0008009=IEA, GO:0006955=IEA, GO:0006954=IEA, GO:0006935=IEA, GO:0002237=IDA, GO:0005576=TAS, GO:0005615=IEA} chemotaxis, immune response, inflammatory response, response to molecule of bacterial origin extracellular region, extracellular space chemokine activity Human CXCL3 Reactome UniProtKB {GO:0008009=GO_REF:0000024, GO:0006955=GO_REF:0000002, GO:0006954=GO_REF:0000037, GO:0030593=GO_REF:0000024, GO:0005576=Reactome:REACT_22289, GO:0005615=PMID:10095777} P19876 C-X-C motif chemokine 3 protein 20080717 {GO:0008009=ISS, GO:0006955=IEA, GO:0006954=IEA, GO:0030593=ISS, GO:0005576=TAS, GO:0005615=IDA} immune response, inflammatory response, neutrophil chemotaxis extracellular region, extracellular space chemokine activity Human CXCL5 Reactome UniProtKB {GO:0007165=PMID:10820279, GO:0008009=GO_REF:0000002, GO:0008284=PMID:10463948, GO:0006955=GO_REF:0000002, GO:0006935=PMID:10820279, GO:0007267=PMID:7929219, GO:0005576=Reactome:REACT_22289, GO:0005615=GO_REF:0000037} P42830 C-X-C motif chemokine 5 protein 20080717 {GO:0007165=TAS, GO:0008009=IEA, GO:0008284=TAS, GO:0006955=IEA, GO:0006935=TAS, GO:0007267=TAS, GO:0005576=TAS, GO:0005615=IEA} cell-cell signaling, chemotaxis, immune response, positive regulation of cell proliferation, signal transduction extracellular region, extracellular space chemokine activity Human CXCL6 Reactome UniProtKB {GO:0007165=PMID:9164944, GO:0008009=GO_REF:0000002, GO:0006955=GO_REF:0000002, GO:0006954=PMID:8399143, GO:0006935=GO_REF:0000037, GO:0007267=PMID:9164944, GO:0005576=Reactome:REACT_22289, GO:0008201=GO_REF:0000037, GO:0005615=GO_REF:0000037} P80162 C-X-C motif chemokine 6 protein 20080717 {GO:0007165=TAS, GO:0008009=IEA, GO:0006955=IEA, GO:0006954=TAS, GO:0006935=IEA, GO:0007267=TAS, GO:0005576=TAS, GO:0008201=IEA, GO:0005615=IEA} cell-cell signaling, chemotaxis, immune response, inflammatory response, signal transduction extracellular region, extracellular space chemokine activity, heparin binding Human CXCL9 Reactome UniProtKB {GO:0008009=GO_REF:0000002, GO:0007267=PMID:8476424, GO:0005576=Reactome:REACT_22289, GO:0006952=PMID:2115167, GO:0005615=GO_REF:0000019, GO:0005125=PMID:2115167, GO:0007165=PMID:10201901, GO:0006955=GO_REF:0000002, GO:0051607=GO_REF:0000019, GO:0006968=PMID:10570316, GO:0006954=GO_REF:0000037, GO:0006935=GO_REF:0000002, GO:0007186=PMID:10903763, GO:0009897=GO_REF:0000019} Q07325 C-X-C motif chemokine 9 protein 20080717 {GO:0008009=IEA, GO:0007267=TAS, GO:0005576=TAS, GO:0006952=TAS, GO:0005615=IEA, GO:0005125=TAS, GO:0007165=TAS, GO:0006955=IEA, GO:0051607=IEA, GO:0006968=TAS, GO:0006954=IEA, GO:0006935=IEA, GO:0007186=TAS, GO:0009897=IEA} G-protein coupled receptor signaling pathway, cell-cell signaling, cellular defense response, chemotaxis, defense response, defense response to virus, immune response, inflammatory response, signal transduction external side of plasma membrane, extracellular region, extracellular space chemokine activity, cytokine activity Human CXCR1 GOC UniProtKB {GO:0031584=GO_REF:0000002, GO:0070098=PMID:1840701, GO:0005886=Reactome:REACT_22289, GO:0004930=PMID:8381837, GO:0030818=GO_REF:0000002, GO:0002407=PMID:16621978, GO:0004918=PMID:10734056, GO:0019959=PMID:11564821, GO:0007204=GO_REF:0000002, GO:0031682=GO_REF:0000002, GO:0006954=PMID:10725748, GO:0006935=PMID:10725748, GO:0007186=PMID:8381837, GO:0016020=PMID:10725748, GO:0004950=PMID:1840701, GO:0038112=PMID:10734056, GO:0016021=GO_REF:0000037, GO:0007166=PMID:10734056} P25024 C-X-C chemokine receptor type 1 protein 20130413 {GO:0031584=IEA, GO:0070098=TAS, GO:0005886=TAS, GO:0004930=TAS, GO:0030818=IEA, GO:0002407=TAS, GO:0004918=IDA, GO:0019959=IPI, GO:0007204=IEA, GO:0031682=IEA, GO:0006954=TAS, GO:0006935=TAS, GO:0007186=TAS, GO:0016020=TAS, GO:0004950=TAS, GO:0038112=IDA, GO:0016021=IEA, GO:0007166=IDA} G-protein coupled receptor signaling pathway, activation of phospholipase D activity, cell surface receptor signaling pathway, chemokine-mediated signaling pathway, chemotaxis, dendritic cell chemotaxis, elevation of cytosolic calcium ion concentration, inflammatory response, interleukin-8-mediated signaling pathway, negative regulation of cAMP biosynthetic process integral to membrane, membrane, plasma membrane G-protein coupled receptor activity, G-protein gamma-subunit binding, chemokine receptor activity, interleukin-8 binding, interleukin-8 receptor activity Human CXCR2 GOC UniProtKB {GO:0008284=PMID:10438939, GO:0005886=Reactome:REACT_22289, GO:0030818=GO_REF:0000002, GO:0007200=PMID:10438939, GO:0019959=PMID:1840701, GO:0007204=GO_REF:0000019, GO:0042629=PMID:9725262, GO:0005622=PMID:10878382, GO:0006954=PMID:9725262, GO:0006935=PMID:10725748, GO:0038112=PMID:10820279, GO:0004871=PMID:10878382, GO:0009986=PMID:10878382, GO:0030593=PMID:10820279, GO:0002407=PMID:16621978, GO:0006915=GO_REF:0000019, GO:0004918=PMID:10820279, GO:0031682=GO_REF:0000002, GO:0007165=PMID:10820279, GO:0006968=PMID:10725748, GO:0016020=PMID:10725748, GO:0016494=PMID:10878382, GO:0005887=PMID:10438939, GO:0016021=GO_REF:0000038, GO:0042119=PMID:10878382, GO:0007166=PMID:10734056} P25025 C-X-C chemokine receptor type 2 protein 20130413 {GO:0008284=IDA, GO:0005886=TAS, GO:0030818=IEA, GO:0007200=IDA, GO:0019959=IPI, GO:0007204=IEA, GO:0042629=IDA, GO:0005622=IDA, GO:0006954=TAS, GO:0006935=IDA, GO:0038112=IDA, GO:0004871=IDA, GO:0009986=IDA, GO:0030593=IDA, GO:0002407=TAS, GO:0006915=IEA, GO:0004918=IDA, GO:0031682=IEA, GO:0007165=IDA, GO:0006968=IDA, GO:0016020=IDA, GO:0016494=IDA, GO:0005887=TAS, GO:0016021=IEA, GO:0042119=IDA, GO:0007166=IDA} apoptotic process, cell surface receptor signaling pathway, cellular defense response, chemotaxis, dendritic cell chemotaxis, elevation of cytosolic calcium ion concentration, inflammatory response, interleukin-8-mediated signaling pathway, negative regulation of cAMP biosynthetic process, neutrophil activation, neutrophil chemotaxis, phospholipase C-activating G-protein coupled receptor signaling pathway, positive regulation of cell proliferation, signal transduction cell surface, integral to membrane, integral to plasma membrane, intracellular, mast cell granule, membrane, plasma membrane C-X-C chemokine receptor activity, G-protein gamma-subunit binding, interleukin-8 binding, interleukin-8 receptor activity, signal transducer activity Human CXCR3 BHF-UCL UniProtKB {GO:0019722=GO_REF:0000019, GO:0005886=Reactome:REACT_22289, GO:0006928=PMID:10741397, GO:0006915=GO_REF:0000037, GO:0002685=GO_REF:0000002, GO:0001525=GO_REF:0000037, GO:0019958=GO_REF:0000002, GO:0007204=GO_REF:0000019, GO:0019957=GO_REF:0000002, GO:0010818=GO_REF:0000019, GO:0019956=PMID:11554781, GO:0033622=GO_REF:0000002, GO:0005737=PMID:10903743, GO:0006954=GO_REF:0000002, GO:0006935=PMID:10903763, GO:0043405=GO_REF:0000002, GO:0005887=PMID:9064356, GO:0043551=GO_REF:0000002, GO:0016494=GO_REF:0000019, GO:0004950=PMID:9064356, GO:0007155=PMID:10942362, GO:0009897=GO_REF:0000019} P49682 C-X-C chemokine receptor type 3 protein 20110329 {GO:0019722=IEA, GO:0005886=TAS, GO:0006928=TAS, GO:0006915=IEA, GO:0002685=IEA, GO:0001525=IEA, GO:0019958=IEA, GO:0007204=IEA, GO:0019957=IEA, GO:0010818=IEA, GO:0019956=IPI, GO:0033622=IEA, GO:0005737=TAS, GO:0006954=IEA, GO:0006935=TAS, GO:0043405=IEA, GO:0005887=TAS, GO:0043551=IEA, GO:0016494=IEA, GO:0004950=TAS, GO:0007155=TAS, GO:0009897=IEA} T cell chemotaxis, angiogenesis, apoptotic process, calcium-mediated signaling, cell adhesion, cellular component movement, chemotaxis, elevation of cytosolic calcium ion concentration, inflammatory response, integrin activation, regulation of MAP kinase activity, regulation of leukocyte migration, regulation of phosphatidylinositol 3-kinase activity cytoplasm, external side of plasma membrane, integral to plasma membrane, plasma membrane C-C chemokine binding, C-X-C chemokine binding, C-X-C chemokine receptor activity, chemokine binding, chemokine receptor activity Human UniProtKB:O43927 CXCR4 BHF-UCL UniProtKB {GO:0005515=PMID:10644702, GO:0022415=Reactome:REACT_6266, GO:0043130=PMID:20228059, GO:0019722=PMID:19064997, GO:0005886=Reactome:REACT_14783, GO:0030260=Reactome:REACT_6903, GO:0007281=GO_REF:0000019, GO:0019958=GO_REF:0000002, GO:0007204=GO_REF:0000002, GO:0030426=GO_REF:0000019, GO:0061351=GO_REF:0000019, GO:0000187=PMID:10570282, GO:0005737=PMID:10415069, GO:0006954=PMID:8276799, GO:0042098=GO_REF:0000019, GO:0050920=PMID:19106094, GO:0016032=Reactome:REACT_6256, GO:0031252=PMID:12421915, GO:0031625=PMID:19116316, GO:0032027=PMID:12421915, GO:0030334=GO_REF:0000019, GO:0001666=PMID:15174142, GO:0008354=GO_REF:0000019, GO:0001569=GO_REF:0000019, GO:0009986=PMID:10521508, GO:0004930=PMID:8276799, GO:0001667=GO_REF:0000019, GO:0002407=PMID:16621978, GO:0006915=PMID:10942389, GO:0003779=PMID:12421915, GO:0031410=PMID:10521508, GO:0009615=PMID:10583963, GO:0015026=PMID:10754293, GO:0008045=GO_REF:0000019, GO:0007186=PMID:10644702, GO:0007420=GO_REF:0000019, GO:0016494=PMID:9468539, GO:0048714=GO_REF:0000024, GO:0019048=GO_REF:0000037, GO:0043217=GO_REF:0000024, GO:0016023=PMID:19106094, GO:0016021=GO_REF:0000037, GO:0042119=GO_REF:0000002, GO:0001764=GO_REF:0000019, GO:0009897=GO_REF:0000019} P61073 C-X-C chemokine receptor type 4 protein 20110713 {GO:0005515=IPI, GO:0022415=TAS, GO:0043130=IDA, GO:0019722=IMP, GO:0005886=TAS, GO:0030260=TAS, GO:0007281=IEA, GO:0019958=IEA, GO:0007204=IEA, GO:0030426=IEA, GO:0061351=IEA, GO:0000187=TAS, GO:0005737=TAS, GO:0006954=TAS, GO:0042098=IEA, GO:0050920=IMP, GO:0016032=TAS, GO:0031252=IDA, GO:0031625=IPI, GO:0032027=IDA, GO:0030334=IEA, GO:0001666=IEP, GO:0008354=IEA, GO:0001569=IEA, GO:0009986=IDA, GO:0004930=TAS, GO:0001667=IEA, GO:0002407=TAS, GO:0006915=TAS, GO:0003779=IDA, GO:0031410=IDA, GO:0009615=TAS, GO:0015026=TAS, GO:0008045=IEA, GO:0007186=IDA, GO:0007420=IEA, GO:0016494=NAS, GO:0048714=ISS, GO:0019048=IEA, GO:0043217=ISS, GO:0016023=IDA, GO:0016021=IEA, GO:0042119=IEA, GO:0001764=IEA, GO:0009897=IEA} G-protein coupled receptor signaling pathway, T cell proliferation, activation of MAPK activity, ameboidal cell migration, apoptotic process, brain development, calcium-mediated signaling, dendritic cell chemotaxis, elevation of cytosolic calcium ion concentration, entry into host cell, germ cell development, germ cell migration, inflammatory response, motor neuron axon guidance, myelin maintenance, neural precursor cell proliferation, neuron migration, neutrophil activation, patterning of blood vessels, positive regulation of oligodendrocyte differentiation, regulation of cell migration, regulation of chemotaxis, response to hypoxia, response to virus, viral reproduction, viral reproductive process, virus-host interaction cell leading edge, cell surface, cytoplasm, cytoplasmic membrane-bounded vesicle, cytoplasmic vesicle, external side of plasma membrane, growth cone, integral to membrane, plasma membrane C-X-C chemokine binding, C-X-C chemokine receptor activity, G-protein coupled receptor activity, actin binding, coreceptor activity, myosin light chain binding, protein binding, ubiquitin binding, ubiquitin protein ligase binding Human UniProtKB:P70658 CXCR5 Reactome UniProtKB {GO:0042113=GO_REF:0000037, GO:0006955=GO_REF:0000002, GO:0005886=Reactome:REACT_22289, GO:0007186=PMID:1425907, GO:0006935=GO_REF:0000002, GO:0005887=PMID:1425907, GO:0004930=PMID:1425907, GO:0016494=GO_REF:0000002, GO:0006928=PMID:1425907, GO:0019958=GO_REF:0000002, GO:0007204=GO_REF:0000002, GO:0048535=GO_REF:0000019} P32302 C-X-C chemokine receptor type 5 protein 20100217 {GO:0042113=IEA, GO:0006955=IEA, GO:0005886=TAS, GO:0007186=TAS, GO:0006935=IEA, GO:0005887=TAS, GO:0004930=TAS, GO:0016494=IEA, GO:0006928=TAS, GO:0019958=IEA, GO:0007204=IEA, GO:0048535=IEA} B cell activation, G-protein coupled receptor signaling pathway, cellular component movement, chemotaxis, elevation of cytosolic calcium ion concentration, immune response, lymph node development integral to plasma membrane, plasma membrane C-X-C chemokine binding, C-X-C chemokine receptor activity, G-protein coupled receptor activity Human CXCR6 Reactome UniProtKB {GO:0016464=GO_REF:0000002, GO:0006954=GO_REF:0000002, GO:0005886=Reactome:REACT_22289, GO:0007186=PMID:9166430, GO:0006935=GO_REF:0000002, GO:0004930=PMID:9166430, GO:0005887=PMID:9166430, GO:0016494=GO_REF:0000019, GO:0015026=GO_REF:0000002, GO:0019079=PMID:9230441, GO:0007204=GO_REF:0000002, GO:0051133=GO_REF:0000002} O00574 C-X-C chemokine receptor type 6 protein 20100217 {GO:0016464=IEA, GO:0006954=IEA, GO:0005886=TAS, GO:0007186=TAS, GO:0006935=IEA, GO:0004930=TAS, GO:0005887=TAS, GO:0016494=IEA, GO:0015026=IEA, GO:0019079=TAS, GO:0007204=IEA, GO:0051133=IEA} G-protein coupled receptor signaling pathway, chemotaxis, elevation of cytosolic calcium ion concentration, inflammatory response, regulation of NK T cell activation, viral genome replication integral to plasma membrane, plasma membrane C-X-C chemokine receptor activity, G-protein coupled receptor activity, chloroplast protein-transporting ATPase activity, coreceptor activity Human CXCR7 BHF-UCL UniProtKB {GO:0043066=PMID:20388803, GO:0048471=GO_REF:0000039, GO:0070098=PMID:20388803, GO:0005886=Reactome:REACT_22289, GO:0001525=GO_REF:0000002, GO:0015026=GO_REF:0000002, GO:0019956=GO_REF:0000002, GO:0006935=GO_REF:0000002, GO:0016494=PMID:20388803, GO:0019048=GO_REF:0000037, GO:0016021=GO_REF:0000029, GO:0007155=GO_REF:0000037, GO:0055037=GO_REF:0000039, GO:0001570=GO_REF:0000002, GO:0005769=GO_REF:0000039} P25106 C-X-C chemokine receptor type 7 protein 20110708 {GO:0043066=IMP, GO:0048471=IEA, GO:0070098=IMP, GO:0005886=TAS, GO:0001525=IEA, GO:0015026=IEA, GO:0019956=IEA, GO:0006935=IEA, GO:0016494=IMP, GO:0019048=IEA, GO:0016021=NAS, GO:0007155=IEA, GO:0055037=IEA, GO:0001570=IEA, GO:0005769=IEA} angiogenesis, cell adhesion, chemokine-mediated signaling pathway, chemotaxis, negative regulation of apoptotic process, vasculogenesis, virus-host interaction early endosome, integral to membrane, perinuclear region of cytoplasm, plasma membrane, recycling endosome C-X-C chemokine receptor activity, chemokine binding, coreceptor activity Human CXorf23 UniProtKB UniProtKB {GO:0005739=GO_REF:0000039} A2AJT9 Uncharacterized protein CXorf23 protein 20130413 {GO:0005739=IEA} mitochondrion Human UniProtKB-SubCell:SL-0173 CXorf27 InterPro UniProtKB {GO:0046982=GO_REF:0000002} O75409 Huntingtin-interacting protein M protein 20130413 {GO:0046982=IEA} protein heterodimerization activity Human InterPro:IPR009072 CXorf38 null null {} null null null null {} null null null CXorf40A IntAct UniProtKB {GO:0005515=PMID:15541360} Q8TE69 Protein CXorf40A protein 20130415 {GO:0005515=IPI} protein binding Human UniProtKB:P02795 CXorf56 null null {} null null null null {} null null null CXorf57 null null {} null null null null {} null null null CXorf61 null null {} null null null null {} null null null CXorf67 null null {} null null null null {} null null null CXXC1 LIFEdb UniProtKB {GO:0005515=PMID:17998332, GO:0006355=PMID:10688657, GO:0005634=PMID:10688657, GO:0003677=GO_REF:0000002, GO:0042800=PMID:17355966, GO:0006351=GO_REF:0000037, GO:0016363=GO_REF:0000019, GO:0030968=Reactome:REACT_18356, GO:0045322=PMID:10688657, GO:0035097=PMID:17355966, GO:0016607=GO_REF:0000054, GO:0048188=PMID:18838538, GO:0005654=Reactome:REACT_115869, GO:0008270=GO_REF:0000002, GO:0006987=Reactome:REACT_18368, GO:0045893=PMID:10688657, GO:0044267=Reactome:REACT_17015, GO:0051568=PMID:17355966} Q9P0U4 CpG-binding protein protein 20100607 {GO:0005515=IPI, GO:0006355=IDA, GO:0005634=IDA, GO:0003677=IEA, GO:0042800=IDA, GO:0006351=IEA, GO:0016363=IEA, GO:0030968=TAS, GO:0045322=IDA, GO:0035097=IDA, GO:0016607=IDA, GO:0048188=IDA, GO:0005654=TAS, GO:0008270=IEA, GO:0006987=TAS, GO:0045893=IDA, GO:0044267=TAS, GO:0051568=IDA} activation of signaling protein activity involved in unfolded protein response, cellular protein metabolic process, endoplasmic reticulum unfolded protein response, histone H3-K4 methylation, positive regulation of transcription, DNA-dependent, regulation of transcription, DNA-dependent, transcription, DNA-dependent Set1C/COMPASS complex, histone methyltransferase complex, nuclear matrix, nuclear speck, nucleoplasm, nucleus DNA binding, histone methyltransferase activity (H3-K4 specific), protein binding, unmethylated CpG binding, zinc ion binding Human CXXC4 BHF-UCL UniProtKB {GO:0005737=PMID:11113207, GO:0030178=PMID:11113207, GO:0016023=GO_REF:0000019, GO:0008270=GO_REF:0000002, GO:0007352=GO_REF:0000024, GO:0031410=PMID:11113207, GO:0030165=PMID:11113207, GO:0016055=GO_REF:0000019, GO:0003677=GO_REF:0000002} Q9H2H0 CXXC-type zinc finger protein 4 protein 20080926 {GO:0005737=IDA, GO:0030178=IDA, GO:0016023=IEA, GO:0008270=IEA, GO:0007352=ISS, GO:0031410=IDA, GO:0030165=IPI, GO:0016055=IEA, GO:0003677=IEA} Wnt receptor signaling pathway, negative regulation of Wnt receptor signaling pathway, zygotic specification of dorsal/ventral axis cytoplasm, cytoplasmic membrane-bounded vesicle, cytoplasmic vesicle DNA binding, PDZ domain binding, zinc ion binding Human UniProtKB:Q92997 CXXC5 GOC UniProtKB {GO:0007165=PMID:12761501, GO:0005737=GO_REF:0000039, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0004871=PMID:12761501, GO:0043123=PMID:12761501, GO:0003677=GO_REF:0000002} Q7LFL8 CXXC-type zinc finger protein 5 protein 20130413 {GO:0007165=IMP, GO:0005737=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0004871=IMP, GO:0043123=IMP, GO:0003677=IEA} positive regulation of I-kappaB kinase/NF-kappaB cascade, signal transduction cytoplasm, nucleus DNA binding, signal transducer activity, zinc ion binding Human CYB561 HGNC UniProtKB {GO:0000293=PMID:14499595, GO:0022865=PMID:7559396, GO:0016021=PMID:7559396, GO:0022900=PMID:7559396, GO:0046872=GO_REF:0000037} P49447 Cytochrome b561 protein 20060201 {GO:0000293=ISS, GO:0022865=NAS, GO:0016021=NAS, GO:0022900=NAS, GO:0046872=IEA} electron transport chain integral to membrane ferric-chelate reductase activity, metal ion binding, transmembrane electron transfer carrier Human UniProtKB:Q60720 CYB561D2 UniProtKB UniProtKB {GO:0016021=GO_REF:0000037, GO:0022900=GO_REF:0000037, GO:0046872=GO_REF:0000037} O14569 Cytochrome b561 domain-containing protein 2 protein 20130413 {GO:0016021=IEA, GO:0022900=IEA, GO:0046872=IEA} electron transport chain integral to membrane metal ion binding Human UniProtKB-KW:KW-0479 CYB5A BHF-UCL UniProtKB {GO:0004129=PMID:1712589, GO:0006767=Reactome:REACT_11238, GO:0005741=Reactome:REACT_11182, GO:0044281=Reactome:REACT_111217, GO:0046872=GO_REF:0000037, GO:0005739=GO_REF:0000019, GO:0019852=Reactome:REACT_11202, GO:0004033=Reactome:REACT_11100, GO:0006766=Reactome:REACT_11193, GO:0005789=GO_REF:0000039, GO:0016021=GO_REF:0000037, GO:0019899=PMID:15680923, GO:0022900=GO_REF:0000037, GO:0020037=GO_REF:0000002} P00167 Cytochrome b5 protein 20100205 {GO:0004129=TAS, GO:0006767=TAS, GO:0005741=TAS, GO:0044281=TAS, GO:0046872=IEA, GO:0005739=IEA, GO:0019852=TAS, GO:0004033=TAS, GO:0006766=TAS, GO:0005789=IEA, GO:0016021=IEA, GO:0019899=IPI, GO:0022900=IEA, GO:0020037=IEA} L-ascorbic acid metabolic process, electron transport chain, small molecule metabolic process, vitamin metabolic process, water-soluble vitamin metabolic process endoplasmic reticulum membrane, integral to membrane, mitochondrial outer membrane, mitochondrion aldo-keto reductase (NADP) activity, cytochrome-c oxidase activity, enzyme binding, heme binding, metal ion binding Human UniProtKB:P08684 CYB5B UniProtKB UniProtKB {GO:0005743=GO_REF:0000019, GO:0005741=GO_REF:0000039, GO:0016021=GO_REF:0000037, GO:0022900=GO_REF:0000037, GO:0008047=GO_REF:0000019, GO:0046872=GO_REF:0000037, GO:0020037=PMID:20861021} O43169 Cytochrome b5 type B protein 20111031 {GO:0005743=IEA, GO:0005741=IEA, GO:0016021=IEA, GO:0022900=IEA, GO:0008047=IEA, GO:0046872=IEA, GO:0020037=IDA} electron transport chain integral to membrane, mitochondrial inner membrane, mitochondrial outer membrane enzyme activator activity, heme binding, metal ion binding Human CYB5D1 UniProtKB UniProtKB {GO:0046872=GO_REF:0000037, GO:0020037=GO_REF:0000002} Q6P9G0 Cytochrome b5 domain-containing protein 1 protein 20130413 {GO:0046872=IEA, GO:0020037=IEA} heme binding, metal ion binding Human UniProtKB-KW:KW-0479 CYB5R1 ENSEMBL UniProtKB {GO:0005739=GO_REF:0000019, GO:0004128=GO_REF:0000003, GO:0016126=GO_REF:0000037, GO:0016491=GO_REF:0000038, GO:0016021=GO_REF:0000037} Q9UHQ9 NADH-cytochrome b5 reductase 1 protein 20130413 {GO:0005739=IEA, GO:0004128=IEA, GO:0016126=IEA, GO:0016491=IEA, GO:0016021=IEA} sterol biosynthetic process integral to membrane, mitochondrion cytochrome-b5 reductase activity, acting on NAD(P)H, oxidoreductase activity Human Ensembl:ENSMUSP00000027726 CYB5R2 UniProtKB UniProtKB {GO:0005739=GO_REF:0000019, GO:0016020=PMID:10611283, GO:0004128=PMID:10611283, GO:0016126=GO_REF:0000037, GO:0016491=GO_REF:0000002, GO:0055114=PMID:10611283} Q6BCY4 NADH-cytochrome b5 reductase 2 protein 20070906 {GO:0005739=IEA, GO:0016020=IDA, GO:0004128=IDA, GO:0016126=IEA, GO:0016491=IEA, GO:0055114=IDA} oxidation-reduction process, sterol biosynthetic process membrane, mitochondrion cytochrome-b5 reductase activity, acting on NAD(P)H, oxidoreductase activity Human CYB5R3 HPA UniProtKB {GO:0006695=GO_REF:0000037, GO:0016208=GO_REF:0000019, GO:0005833=PMID:1400360, GO:0004128=Reactome:REACT_11182, GO:0005783=GO_REF:0000052, GO:0008015=PMID:1400360, GO:0050660=GO_REF:0000019, GO:0005743=GO_REF:0000019, GO:0006767=Reactome:REACT_11238, GO:0005741=Reactome:REACT_11182, GO:0044281=Reactome:REACT_111217, GO:0019852=Reactome:REACT_11202, GO:0005737=PMID:9207238, GO:0051287=GO_REF:0000019, GO:0043531=GO_REF:0000019, GO:0016020=PMID:9207238, GO:0006766=Reactome:REACT_11193, GO:0016491=GO_REF:0000002, GO:0005789=GO_REF:0000039} P00387 NADH-cytochrome b5 reductase 3 protein 20080205 {GO:0006695=IEA, GO:0016208=IEA, GO:0005833=TAS, GO:0004128=TAS, GO:0005783=IDA, GO:0008015=TAS, GO:0050660=IEA, GO:0005743=IEA, GO:0006767=TAS, GO:0005741=TAS, GO:0044281=TAS, GO:0019852=TAS, GO:0005737=TAS, GO:0051287=IEA, GO:0043531=IEA, GO:0016020=TAS, GO:0006766=TAS, GO:0016491=IEA, GO:0005789=IEA} L-ascorbic acid metabolic process, blood circulation, cholesterol biosynthetic process, small molecule metabolic process, vitamin metabolic process, water-soluble vitamin metabolic process cytoplasm, endoplasmic reticulum, endoplasmic reticulum membrane, hemoglobin complex, membrane, mitochondrial inner membrane, mitochondrial outer membrane ADP binding, AMP binding, NAD binding, cytochrome-b5 reductase activity, acting on NAD(P)H, flavin adenine dinucleotide binding, oxidoreductase activity Human CYB5R4 UniProtKB UniProtKB {GO:0048471=PMID:10611283, GO:0004128=PMID:10611283, GO:0005783=PMID:15131110, GO:0006801=PMID:10611283, GO:0006091=PMID:10611283, GO:0042593=GO_REF:0000024, GO:0046872=GO_REF:0000037, GO:0016653=PMID:15131110, GO:0003032=PMID:10611283, GO:0016174=PMID:15131110, GO:0048468=GO_REF:0000024, GO:0030073=GO_REF:0000024, GO:0046677=GO_REF:0000024, GO:0055114=PMID:15131110, GO:0020037=GO_REF:0000002} Q7L1T6 Cytochrome b5 reductase 4 protein 20080507 {GO:0048471=IDA, GO:0004128=IDA, GO:0005783=IDA, GO:0006801=IDA, GO:0006091=IDA, GO:0042593=ISS, GO:0046872=IEA, GO:0016653=IDA, GO:0003032=NAS, GO:0016174=IDA, GO:0048468=ISS, GO:0030073=ISS, GO:0046677=ISS, GO:0055114=IDA, GO:0020037=IEA} cell development, detection of oxygen, generation of precursor metabolites and energy, glucose homeostasis, insulin secretion, oxidation-reduction process, response to antibiotic, superoxide metabolic process endoplasmic reticulum, perinuclear region of cytoplasm NAD(P)H oxidase activity, cytochrome-b5 reductase activity, acting on NAD(P)H, heme binding, metal ion binding, oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor Human CYBA BHF-UCL UniProtKB {GO:0045730=PMID:2243141, GO:0005515=PMID:11733522, GO:0002474=Reactome:REACT_75820, GO:0017124=PMID:7938008, GO:0030307=GO_REF:0000019, GO:0006801=PMID:2243141, GO:0071480=GO_REF:0000019, GO:0050665=GO_REF:0000024, GO:0030425=GO_REF:0000019, GO:0046872=GO_REF:0000037, GO:0005739=GO_REF:0000019, GO:0016324=GO_REF:0000019, GO:0006954=PMID:2243141, GO:0071230=GO_REF:0000019, GO:0016175=PMID:1763037, GO:0071356=GO_REF:0000019, GO:0043025=GO_REF:0000019, GO:0030670=Reactome:REACT_121023, GO:0031667=GO_REF:0000019, GO:0030141=PMID:12005167, GO:0071333=GO_REF:0000019, GO:0090382=Reactome:REACT_121256, GO:0070555=GO_REF:0000019, GO:0042554=PMID:2243141, GO:0005794=GO_REF:0000019, GO:0046982=PMID:12042318, GO:0051701=Reactome:REACT_121237, GO:0042493=GO_REF:0000019, GO:0042590=Reactome:REACT_111119, GO:0009055=PMID:12042318, GO:0014895=GO_REF:0000024, GO:0003106=GO_REF:0000019, GO:0071407=GO_REF:0000019, GO:0001938=GO_REF:0000019, GO:0045087=PMID:2243141, GO:0002479=Reactome:REACT_111174, GO:0017004=PMID:7938008, GO:0043020=PMID:3305576, GO:0022900=GO_REF:0000037, GO:0071260=GO_REF:0000019, GO:0055114=PMID:2243141, GO:0020037=GO_REF:0000002} P13498 Cytochrome b-245 light chain protein 20080811 {GO:0045730=IMP, GO:0005515=IPI, GO:0002474=TAS, GO:0017124=IPI, GO:0030307=IEA, GO:0006801=IMP, GO:0071480=IEA, GO:0050665=ISS, GO:0030425=IEA, GO:0046872=IEA, GO:0005739=IEA, GO:0016324=IEA, GO:0006954=IMP, GO:0071230=IEA, GO:0016175=IMP, GO:0071356=IEA, GO:0043025=IEA, GO:0030670=TAS, GO:0031667=IEA, GO:0030141=TAS, GO:0071333=IEA, GO:0090382=TAS, GO:0070555=IEA, GO:0042554=IMP, GO:0005794=IEA, GO:0046982=IPI, GO:0051701=TAS, GO:0042493=IEA, GO:0042590=TAS, GO:0009055=IDA, GO:0014895=ISS, GO:0003106=IEA, GO:0071407=IEA, GO:0001938=IEA, GO:0045087=IMP, GO:0002479=TAS, GO:0017004=IDA, GO:0043020=IDA, GO:0022900=IEA, GO:0071260=IEA, GO:0055114=IMP, GO:0020037=IEA} antigen processing and presentation of exogenous peptide antigen via MHC class I, antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent, antigen processing and presentation of peptide antigen via MHC class I, cellular response to amino acid stimulus, cellular response to gamma radiation, cellular response to glucose stimulus, cellular response to mechanical stimulus, cellular response to organic cyclic compound, cellular response to tumor necrosis factor, cytochrome complex assembly, electron transport chain, hydrogen peroxide biosynthetic process, inflammatory response, innate immune response, interaction with host, negative regulation of glomerular filtration by angiotensin, oxidation-reduction process, phagosome maturation, positive regulation of cell growth, positive regulation of endothelial cell proliferation, respiratory burst, response to drug, response to interleukin-1, response to nutrient levels, smooth muscle hypertrophy, superoxide anion generation, superoxide metabolic process Golgi apparatus, NADPH oxidase complex, apical plasma membrane, dendrite, mitochondrion, neuronal cell body, phagocytic vesicle membrane, secretory granule SH3 domain binding, electron carrier activity, heme binding, metal ion binding, protein binding, protein heterodimerization activity, superoxide-generating NADPH oxidase activity Human CYBB BHF-UCL UniProtKB {GO:0005515=PMID:3305576, GO:0045730=PMID:9774399, GO:0002474=Reactome:REACT_75820, GO:0005886=GO_REF:0000019, GO:0050660=PMID:9774399, GO:0006801=PMID:12042318, GO:0050665=GO_REF:0000019, GO:0046872=GO_REF:0000037, GO:0005739=GO_REF:0000019, GO:0006954=PMID:7719350, GO:0016175=PMID:12042318, GO:0030670=Reactome:REACT_121023, GO:0090382=Reactome:REACT_121256, GO:0042554=PMID:12042318, GO:0005244=GO_REF:0000037, GO:0051701=Reactome:REACT_121237, GO:0046982=PMID:12042318, GO:0042590=Reactome:REACT_111119, GO:0009055=PMID:12042318, GO:0005887=PMID:15233623, GO:0045087=PMID:9774399, GO:0016491=GO_REF:0000038, GO:0002479=Reactome:REACT_111174, GO:0016021=GO_REF:0000038, GO:0043020=PMID:12716910, GO:0022900=GO_REF:0000037, GO:0020037=PMID:9774399, GO:0055114=PMID:12042318} P04839 Cytochrome b-245 heavy chain protein 20080811 {GO:0005515=IPI, GO:0045730=IMP, GO:0002474=TAS, GO:0005886=IEA, GO:0050660=IMP, GO:0006801=IDA, GO:0050665=IEA, GO:0046872=IEA, GO:0005739=IEA, GO:0006954=TAS, GO:0016175=IDA, GO:0030670=TAS, GO:0090382=TAS, GO:0042554=IDA, GO:0005244=IEA, GO:0051701=TAS, GO:0046982=IPI, GO:0042590=TAS, GO:0009055=IDA, GO:0005887=IDA, GO:0045087=IMP, GO:0016491=IEA, GO:0002479=TAS, GO:0016021=IEA, GO:0043020=TAS, GO:0022900=IEA, GO:0020037=IMP, GO:0055114=IDA} antigen processing and presentation of exogenous peptide antigen via MHC class I, antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent, antigen processing and presentation of peptide antigen via MHC class I, electron transport chain, hydrogen peroxide biosynthetic process, inflammatory response, innate immune response, interaction with host, oxidation-reduction process, phagosome maturation, respiratory burst, superoxide anion generation, superoxide metabolic process NADPH oxidase complex, integral to membrane, integral to plasma membrane, mitochondrion, phagocytic vesicle membrane, plasma membrane electron carrier activity, flavin adenine dinucleotide binding, heme binding, metal ion binding, oxidoreductase activity, protein binding, protein heterodimerization activity, superoxide-generating NADPH oxidase activity, voltage-gated ion channel activity Human CYBRD1 Reactome UniProtKB {GO:0006879=Reactome:REACT_25060, GO:0005886=Reactome:REACT_25114, GO:0000293=PMID:14499595, GO:0010039=GO_REF:0000019, GO:0016722=Reactome:REACT_25114, GO:0031526=GO_REF:0000019, GO:0016021=GO_REF:0000037, GO:0022900=GO_REF:0000037, GO:0055085=Reactome:REACT_15518, GO:0046872=GO_REF:0000037} Q53TN4 Cytochrome b reductase 1 protein 20121220 {GO:0006879=TAS, GO:0005886=TAS, GO:0000293=IDA, GO:0010039=IEA, GO:0016722=TAS, GO:0031526=IEA, GO:0016021=IEA, GO:0022900=IEA, GO:0055085=TAS, GO:0046872=IEA} cellular iron ion homeostasis, electron transport chain, response to iron ion, transmembrane transport brush border membrane, integral to membrane, plasma membrane ferric-chelate reductase activity, metal ion binding, oxidoreductase activity, oxidizing metal ions Human CYC1 HPA UniProtKB {GO:0005739=GO_REF:0000052, GO:0022904=Reactome:REACT_22393, GO:0005737=GO_REF:0000052, GO:0045155=PMID:2536365, GO:0030054=GO_REF:0000052, GO:0005506=GO_REF:0000002, GO:0070469=GO_REF:0000037, GO:0005743=Reactome:REACT_6300, GO:0044281=Reactome:REACT_111217, GO:0016021=GO_REF:0000037, GO:0020037=GO_REF:0000002} P08574 Cytochrome c1, heme protein, mitochondrial protein 20101115 {GO:0005739=IDA, GO:0022904=TAS, GO:0005737=IDA, GO:0045155=TAS, GO:0030054=IDA, GO:0005506=IEA, GO:0070469=IEA, GO:0005743=TAS, GO:0044281=TAS, GO:0016021=IEA, GO:0020037=IEA} respiratory electron transport chain, small molecule metabolic process cell junction, cytoplasm, integral to membrane, mitochondrial inner membrane, mitochondrion, respiratory chain electron transporter, transferring electrons from CoQH2-cytochrome c reductase complex and cytochrome c oxidase complex activity, heme binding, iron ion binding Human CYCS LIFEdb UniProtKB {GO:0005515=PMID:9267021, GO:0008635=Reactome:REACT_607, GO:0005506=GO_REF:0000002, GO:0070469=GO_REF:0000037, GO:0005743=Reactome:REACT_6300, GO:0000159=PMID:8206937, GO:0009055=GO_REF:0000002, GO:0006915=Reactome:REACT_578, GO:0005634=GO_REF:0000054, GO:0044281=Reactome:REACT_111217, GO:0097193=Reactome:REACT_964, GO:0005829=Reactome:REACT_2165, GO:0022904=Reactome:REACT_6305, GO:0005739=GO_REF:0000038, GO:0005758=Reactome:REACT_535, GO:0045155=PMID:8689682, GO:0045333=PMID:10383829, GO:0006309=PMID:8689682, GO:0004722=PMID:8206937, GO:0022900=GO_REF:0000038, GO:0020037=PMID:9515723} P99999 Cytochrome c protein 20100607 {GO:0005515=IPI, GO:0008635=TAS, GO:0005506=IEA, GO:0070469=IEA, GO:0005743=TAS, GO:0000159=TAS, GO:0009055=IEA, GO:0006915=TAS, GO:0005634=IDA, GO:0044281=TAS, GO:0097193=TAS, GO:0005829=TAS, GO:0022904=TAS, GO:0005739=IEA, GO:0005758=TAS, GO:0045155=IDA, GO:0045333=TAS, GO:0006309=IMP, GO:0004722=TAS, GO:0022900=IEA, GO:0020037=TAS} activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c, apoptotic DNA fragmentation, apoptotic process, cellular respiration, electron transport chain, intrinsic apoptotic signaling pathway, respiratory electron transport chain, small molecule metabolic process cytosol, mitochondrial inner membrane, mitochondrial intermembrane space, mitochondrion, nucleus, protein phosphatase type 2A complex, respiratory chain electron carrier activity, electron transporter, transferring electrons from CoQH2-cytochrome c reductase complex and cytochrome c oxidase complex activity, heme binding, iron ion binding, protein binding, protein serine/threonine phosphatase activity Human CYFIP1 IntAct UniProtKB {GO:0005515=PMID:18805096, GO:0043005=GO_REF:0000024, GO:0048471=GO_REF:0000024, GO:0030054=GO_REF:0000037, GO:0008360=GO_REF:0000037, GO:0030032=GO_REF:0000024, GO:0045202=GO_REF:0000037, GO:0048675=PMID:16260607, GO:0001726=GO_REF:0000024, GO:0030027=GO_REF:0000024, GO:0031529=GO_REF:0000024, GO:0048365=GO_REF:0000024, GO:0051015=GO_REF:0000024, GO:0005845=GO_REF:0000024} Q7L576 Cytoplasmic FMR1-interacting protein 1 protein 20130415 {GO:0005515=IPI, GO:0043005=ISS, GO:0048471=ISS, GO:0030054=IEA, GO:0008360=IEA, GO:0030032=ISS, GO:0045202=IEA, GO:0048675=IMP, GO:0001726=ISS, GO:0030027=ISS, GO:0031529=ISS, GO:0048365=ISS, GO:0051015=ISS, GO:0005845=ISS} axon extension, lamellipodium assembly, regulation of cell shape, ruffle organization cell junction, lamellipodium, mRNA cap binding complex, neuron projection, perinuclear region of cytoplasm, ruffle, synapse Rac GTPase binding, actin filament binding, protein binding Human UniProtKB:P63073 CYFIP2 BHF-UCL UniProtKB {GO:0005515=PMID:11438699, GO:0043005=GO_REF:0000039, GO:0048471=PMID:10449408, GO:0030054=GO_REF:0000037, GO:0006915=PMID:10449408, GO:0045202=PMID:11438699, GO:0097202=PMID:18387192, GO:0045862=PMID:18387192, GO:0005829=Reactome:REACT_160291, GO:0005737=PMID:11438699, GO:0016337=PMID:15048733, GO:0045087=Reactome:REACT_6802, GO:0038096=Reactome:REACT_160123} Q96F07 Cytoplasmic FMR1-interacting protein 2 protein 20130219 {GO:0005515=IPI, GO:0043005=IEA, GO:0048471=IDA, GO:0030054=IEA, GO:0006915=IDA, GO:0045202=IDA, GO:0097202=IDA, GO:0045862=IDA, GO:0005829=TAS, GO:0005737=IDA, GO:0016337=IDA, GO:0045087=TAS, GO:0038096=TAS} Fc-gamma receptor signaling pathway involved in phagocytosis, activation of cysteine-type endopeptidase activity, apoptotic process, cell-cell adhesion, innate immune response, positive regulation of proteolysis cell junction, cytoplasm, cytosol, neuron projection, perinuclear region of cytoplasm, synapse protein binding Human CYGB UniProtKB UniProtKB {GO:0043005=GO_REF:0000019, GO:0005737=GO_REF:0000039, GO:0004601=PMID:11320098, GO:0019825=GO_REF:0000002, GO:0005506=GO_REF:0000002, GO:0043025=GO_REF:0000019, GO:0005344=PMID:11919282, GO:0006979=PMID:11320098, GO:0015671=PMID:11919282, GO:0020037=GO_REF:0000002} Q8WWM9 Cytoglobin protein 20061120 {GO:0043005=IEA, GO:0005737=IEA, GO:0004601=ISS, GO:0019825=IEA, GO:0005506=IEA, GO:0043025=IEA, GO:0005344=NAS, GO:0006979=ISS, GO:0015671=NAS, GO:0020037=IEA} oxygen transport, response to oxidative stress cytoplasm, neuron projection, neuronal cell body heme binding, iron ion binding, oxygen binding, oxygen transporter activity, peroxidase activity Human UniProtKB:Q921A4 CYHR1 UniProtKB UniProtKB {GO:0048471=GO_REF:0000039, GO:0005737=GO_REF:0000019, GO:0008270=GO_REF:0000002, GO:0005635=GO_REF:0000019} Q6ZMK1 Cysteine and histidine-rich protein 1 protein 20130413 {GO:0048471=IEA, GO:0005737=IEA, GO:0008270=IEA, GO:0005635=IEA} cytoplasm, nuclear envelope, perinuclear region of cytoplasm zinc ion binding Human UniProtKB-SubCell:SL-0198 CYLC2 UniProtKB UniProtKB {GO:0033150=GO_REF:0000039, GO:0005200=GO_REF:0000002, GO:0007275=GO_REF:0000037, GO:0007283=GO_REF:0000037, GO:0030154=GO_REF:0000037} Q14093 Cylicin-2 protein 20130413 {GO:0033150=IEA, GO:0005200=IEA, GO:0007275=IEA, GO:0007283=IEA, GO:0030154=IEA} cell differentiation, multicellular organismal development, spermatogenesis cytoskeletal calyx structural constituent of cytoskeleton Human UniProtKB-SubCell:SL-0032 CYLD Reactome UniProtKB {GO:0005515=PMID:20227366, GO:0006511=GO_REF:0000002, GO:0005881=PMID:17495026, GO:0042347=PMID:18313383, GO:0048471=GO_REF:0000039, GO:0004843=PMID:18313383, GO:0070423=Reactome:REACT_75776, GO:0035872=Reactome:REACT_75913, GO:0005829=Reactome:REACT_75903, GO:0070536=PMID:18313383, GO:0016055=GO_REF:0000037, GO:0070064=PMID:15341735, GO:0090090=PMID:20227366, GO:0032480=Reactome:REACT_25271, GO:0019901=PMID:17495026, GO:0030496=PMID:17495026, GO:0032088=PMID:18313383, GO:0006917=PMID:21525013, GO:0031234=PMID:20194890, GO:0070507=PMID:20194890, GO:0007346=PMID:17495026, GO:0007049=GO_REF:0000037, GO:0045087=Reactome:REACT_6802, GO:0008270=PMID:18313383, GO:0004221=GO_REF:0000002} Q9NQC7 Ubiquitin carboxyl-terminal hydrolase CYLD protein 20130301 {GO:0005515=IPI, GO:0006511=IEA, GO:0005881=IDA, GO:0042347=IDA, GO:0048471=IEA, GO:0004843=IDA, GO:0070423=TAS, GO:0035872=TAS, GO:0005829=TAS, GO:0070536=IDA, GO:0016055=IEA, GO:0070064=IPI, GO:0090090=IMP, GO:0032480=TAS, GO:0019901=IPI, GO:0030496=IDA, GO:0032088=IDA, GO:0006917=IDA, GO:0031234=IDA, GO:0070507=IMP, GO:0007346=IMP, GO:0007049=IEA, GO:0045087=TAS, GO:0008270=IDA, GO:0004221=IEA} Wnt receptor signaling pathway, cell cycle, induction of apoptosis, innate immune response, negative regulation of NF-kappaB import into nucleus, negative regulation of NF-kappaB transcription factor activity, negative regulation of canonical Wnt receptor signaling pathway, negative regulation of type I interferon production, nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway, nucleotide-binding oligomerization domain containing signaling pathway, protein K63-linked deubiquitination, regulation of microtubule cytoskeleton organization, regulation of mitotic cell cycle, ubiquitin-dependent protein catabolic process cytoplasmic microtubule, cytosol, extrinsic to internal side of plasma membrane, midbody, perinuclear region of cytoplasm proline-rich region binding, protein binding, protein kinase binding, ubiquitin thiolesterase activity, ubiquitin-specific protease activity, zinc ion binding Human CYP11A1 Reactome UniProtKB {GO:0042542=GO_REF:0000019, GO:0006805=Reactome:REACT_13705, GO:0009651=GO_REF:0000019, GO:0018963=GO_REF:0000019, GO:0006701=GO_REF:0000019, GO:0006703=GO_REF:0000019, GO:0071560=GO_REF:0000019, GO:0033591=GO_REF:0000019, GO:0033595=GO_REF:0000019, GO:0014037=GO_REF:0000019, GO:0005759=Reactome:REACT_10084, GO:0060992=GO_REF:0000019, GO:0071356=GO_REF:0000019, GO:0033197=GO_REF:0000019, GO:0018958=GO_REF:0000019, GO:0010332=GO_REF:0000019, GO:0030061=GO_REF:0000019, GO:0051412=GO_REF:0000019, GO:0005506=GO_REF:0000002, GO:0007617=GO_REF:0000019, GO:0042359=GO_REF:0000024, GO:0060135=GO_REF:0000019, GO:0021549=GO_REF:0000019, GO:0043279=GO_REF:0000019, GO:0061370=GO_REF:0000019, GO:0071347=GO_REF:0000019, GO:0006700=Reactome:REACT_11038, GO:0020037=PMID:21636783, GO:0008386=PMID:21636783, GO:0018879=GO_REF:0000019, GO:0044281=Reactome:REACT_111217, GO:0071372=GO_REF:0000019, GO:0005739=GO_REF:0000024, GO:0004497=GO_REF:0000002, GO:0015485=GO_REF:0000019, GO:0071375=GO_REF:0000019, GO:0001101=GO_REF:0000019, GO:0043204=GO_REF:0000019, GO:0071276=GO_REF:0000019, GO:0008202=Reactome:REACT_11057, GO:0071236=GO_REF:0000019, GO:0008203=PMID:21636783, GO:0042493=GO_REF:0000019, GO:0009055=GO_REF:0000002, GO:0044344=GO_REF:0000019, GO:0021766=GO_REF:0000019, GO:0050756=GO_REF:0000019, GO:0018894=GO_REF:0000019, GO:0071222=GO_REF:0000019, GO:0033327=GO_REF:0000019, GO:0017085=GO_REF:0000019, GO:0016705=GO_REF:0000002, GO:0071320=GO_REF:0000019, GO:0060014=GO_REF:0000019} P05108 Cholesterol side-chain cleavage enzyme, mitochondrial protein 20130301 {GO:0042542=IEA, GO:0006805=TAS, GO:0009651=IEA, GO:0018963=IEA, GO:0006701=IEA, GO:0006703=IEA, GO:0071560=IEA, GO:0033591=IEA, GO:0033595=IEA, GO:0014037=IEA, GO:0005759=TAS, GO:0060992=IEA, GO:0071356=IEA, GO:0033197=IEA, GO:0018958=IEA, GO:0010332=IEA, GO:0030061=IEA, GO:0051412=IEA, GO:0005506=IEA, GO:0007617=IEA, GO:0042359=ISS, GO:0060135=IEA, GO:0021549=IEA, GO:0043279=IEA, GO:0061370=IEA, GO:0071347=IEA, GO:0006700=TAS, GO:0020037=IDA, GO:0008386=IDA, GO:0018879=IEA, GO:0044281=TAS, GO:0071372=IEA, GO:0005739=ISS, GO:0004497=IEA, GO:0015485=IEA, GO:0071375=IEA, GO:0001101=IEA, GO:0043204=IEA, GO:0071276=IEA, GO:0008202=TAS, GO:0071236=IEA, GO:0008203=IDA, GO:0042493=IEA, GO:0009055=IEA, GO:0044344=IEA, GO:0021766=IEA, GO:0050756=IEA, GO:0018894=IEA, GO:0071222=IEA, GO:0033327=IEA, GO:0017085=IEA, GO:0016705=IEA, GO:0071320=IEA, GO:0060014=IEA} C21-steroid hormone biosynthetic process, Leydig cell differentiation, Schwann cell differentiation, biphenyl metabolic process, cellular response to antibiotic, cellular response to cAMP, cellular response to cadmium ion, cellular response to fibroblast growth factor stimulus, cellular response to follicle-stimulating hormone stimulus, cellular response to interleukin-1, cellular response to lipopolysaccharide, cellular response to peptide hormone stimulus, cellular response to transforming growth factor beta stimulus, cellular response to tumor necrosis factor, cerebellum development, cholesterol metabolic process, dibenzo-p-dioxin metabolic process, estrogen biosynthetic process, fractalkine metabolic process, granulosa cell differentiation, hippocampus development, maternal process involved in female pregnancy, mating behavior, phenol-containing compound metabolic process, phthalate metabolic process, progesterone biosynthetic process, response to L-ascorbic acid, response to acid, response to alkaloid, response to corticosterone stimulus, response to drug, response to fungicide, response to gamma radiation, response to genistein, response to hydrogen peroxide, response to insecticide, response to salt stress, response to vitamin E, small molecule metabolic process, steroid metabolic process, testosterone biosynthetic process, vitamin D metabolic process, xenobiotic metabolic process mitochondrial crista, mitochondrial matrix, mitochondrion, perikaryon cholesterol binding, cholesterol monooxygenase (side-chain-cleaving) activity, electron carrier activity, heme binding, iron ion binding, monooxygenase activity, oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen Human CYP11B1 UniProtKB UniProtKB {GO:0006705=Reactome:REACT_11047, GO:0006805=Reactome:REACT_13705, GO:0005506=GO_REF:0000002, GO:0006704=Reactome:REACT_11036, GO:0006950=PMID:12452430, GO:0005743=PMID:8506298, GO:0009055=GO_REF:0000002, GO:0042593=PMID:16114325, GO:0004507=PMID:2256920, GO:0044281=Reactome:REACT_111217, GO:0032870=PMID:19342457, GO:0034651=PMID:2022736, GO:0005739=PMID:2256920, GO:0004497=GO_REF:0000038, GO:0006955=PMID:12452430, GO:0035865=PMID:19342457, GO:0006700=PMID:2256920, GO:0008217=PMID:2022736, GO:0032342=PMID:2256920, GO:0016705=GO_REF:0000002, GO:0008202=Reactome:REACT_11057, GO:0020037=GO_REF:0000002} Q4VAR0 CYP11B1 protein protein 20130413 {GO:0006705=TAS, GO:0006805=TAS, GO:0005506=IEA, GO:0006704=TAS, GO:0006950=TAS, GO:0005743=IC, GO:0009055=IEA, GO:0042593=TAS, GO:0004507=IDA, GO:0044281=TAS, GO:0032870=IEP, GO:0034651=IMP, GO:0005739=IDA, GO:0004497=IEA, GO:0006955=TAS, GO:0035865=IEP, GO:0006700=IDA, GO:0008217=IMP, GO:0032342=IDA, GO:0016705=IEA, GO:0008202=TAS, GO:0020037=IEA} C21-steroid hormone biosynthetic process, aldosterone biosynthetic process, cellular response to hormone stimulus, cellular response to potassium ion, cortisol biosynthetic process, glucocorticoid biosynthetic process, glucose homeostasis, immune response, mineralocorticoid biosynthetic process, regulation of blood pressure, response to stress, small molecule metabolic process, steroid metabolic process, xenobiotic metabolic process mitochondrial inner membrane, mitochondrion electron carrier activity, heme binding, iron ion binding, monooxygenase activity, oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, steroid 11-beta-monooxygenase activity Human UniProtKB-KW:KW-0503 CYP11B2 BHF-UCL UniProtKB {GO:0006705=Reactome:REACT_11047, GO:0006805=Reactome:REACT_13705, GO:0005506=GO_REF:0000002, GO:0055075=PMID:9838244, GO:0005743=PMID:2256920, GO:0009055=GO_REF:0000002, GO:0055078=PMID:9838244, GO:0044281=Reactome:REACT_111217, GO:0047783=GO_REF:0000003, GO:0004507=PMID:1741400, GO:0032870=PMID:19342457, GO:0034651=PMID:9703385, GO:0003091=PMID:2256920, GO:0005739=PMID:1741400, GO:0035865=PMID:19342457, GO:0002017=PMID:14614232, GO:0006700=PMID:2256920, GO:0032342=PMID:1741400, GO:0008202=Reactome:REACT_11057, GO:0020037=PMID:2256920} P19099 Cytochrome P450 11B2, mitochondrial protein 20080812 {GO:0006705=TAS, GO:0006805=TAS, GO:0005506=IEA, GO:0055075=IMP, GO:0005743=IC, GO:0009055=IEA, GO:0055078=IMP, GO:0044281=TAS, GO:0047783=IEA, GO:0004507=IDA, GO:0032870=IEP, GO:0034651=IMP, GO:0003091=IC, GO:0005739=IDA, GO:0035865=IEP, GO:0002017=IMP, GO:0006700=IDA, GO:0032342=IDA, GO:0008202=TAS, GO:0020037=IC} C21-steroid hormone biosynthetic process, aldosterone biosynthetic process, cellular response to hormone stimulus, cellular response to potassium ion, cortisol biosynthetic process, mineralocorticoid biosynthetic process, potassium ion homeostasis, regulation of blood volume by renal aldosterone, renal water homeostasis, small molecule metabolic process, sodium ion homeostasis, steroid metabolic process, xenobiotic metabolic process mitochondrial inner membrane, mitochondrion corticosterone 18-monooxygenase activity, electron carrier activity, heme binding, iron ion binding, steroid 11-beta-monooxygenase activity Human CYP17A1 Reactome UniProtKB {GO:0030424=GO_REF:0000019, GO:0006694=PMID:3500022, GO:0006805=Reactome:REACT_13705, GO:0018963=GO_REF:0000019, GO:0030325=GO_REF:0000019, GO:0006702=Reactome:REACT_11059, GO:0005783=PMID:9326943, GO:0006704=Reactome:REACT_11036, GO:0018879=GO_REF:0000019, GO:0044281=Reactome:REACT_111217, GO:0047442=GO_REF:0000003, GO:0051591=GO_REF:0000019, GO:0005739=GO_REF:0000019, GO:0010034=GO_REF:0000019, GO:0071371=GO_REF:0000019, GO:0060992=GO_REF:0000019, GO:0010212=GO_REF:0000019, GO:0043025=GO_REF:0000019, GO:0031667=GO_REF:0000019, GO:0007548=PMID:9326943, GO:0090031=GO_REF:0000019, GO:0018958=GO_REF:0000019, GO:0032526=GO_REF:0000019, GO:0034097=GO_REF:0000019, GO:0008202=Reactome:REACT_11057, GO:0071236=GO_REF:0000019, GO:0005506=GO_REF:0000002, GO:0042493=GO_REF:0000019, GO:0009055=GO_REF:0000002, GO:0004508=PMID:22266943, GO:0009635=GO_REF:0000019, GO:0048545=GO_REF:0000019, GO:0021766=GO_REF:0000019, GO:0018894=GO_REF:0000019, GO:0071222=GO_REF:0000019, GO:0019825=PMID:2808364, GO:0051597=GO_REF:0000019, GO:0042448=PMID:22266943, GO:0005789=Reactome:REACT_10116, GO:0042446=PMID:22266943, GO:0033327=GO_REF:0000019, GO:0017085=GO_REF:0000019, GO:0030728=GO_REF:0000019, GO:0020037=PMID:22266943} P05093 Steroid 17-alpha-hydroxylase/17,20 lyase protein 20130301 {GO:0030424=IEA, GO:0006694=TAS, GO:0006805=TAS, GO:0018963=IEA, GO:0030325=IEA, GO:0006702=TAS, GO:0005783=NAS, GO:0006704=TAS, GO:0018879=IEA, GO:0044281=TAS, GO:0047442=IEA, GO:0051591=IEA, GO:0005739=IEA, GO:0010034=IEA, GO:0071371=IEA, GO:0060992=IEA, GO:0010212=IEA, GO:0043025=IEA, GO:0031667=IEA, GO:0007548=TAS, GO:0090031=IEA, GO:0018958=IEA, GO:0032526=IEA, GO:0034097=IEA, GO:0008202=TAS, GO:0071236=IEA, GO:0005506=IEA, GO:0042493=IEA, GO:0009055=IEA, GO:0004508=IDA, GO:0009635=IEA, GO:0048545=IEA, GO:0021766=IEA, GO:0018894=IEA, GO:0071222=IEA, GO:0019825=TAS, GO:0051597=IEA, GO:0042448=IDA, GO:0005789=TAS, GO:0042446=IDA, GO:0033327=IEA, GO:0017085=IEA, GO:0030728=IEA, GO:0020037=IDA} Leydig cell differentiation, adrenal gland development, androgen biosynthetic process, biphenyl metabolic process, cellular response to antibiotic, cellular response to gonadotropin stimulus, cellular response to lipopolysaccharide, dibenzo-p-dioxin metabolic process, glucocorticoid biosynthetic process, hippocampus development, hormone biosynthetic process, ovulation, phenol-containing compound metabolic process, phthalate metabolic process, positive regulation of steroid hormone biosynthetic process, progesterone metabolic process, response to acetate, response to cAMP, response to cytokine stimulus, response to drug, response to fungicide, response to herbicide, response to insecticide, response to ionizing radiation, response to methylmercury, response to nutrient levels, response to retinoic acid, response to steroid hormone stimulus, sex differentiation, small molecule metabolic process, steroid biosynthetic process, steroid metabolic process, xenobiotic metabolic process axon, endoplasmic reticulum, endoplasmic reticulum membrane, mitochondrion, neuronal cell body 17-alpha-hydroxyprogesterone aldolase activity, electron carrier activity, heme binding, iron ion binding, oxygen binding, steroid 17-alpha-monooxygenase activity Human CYP19A1 InterPro UniProtKB {GO:0006694=PMID:2848247, GO:0006805=Reactome:REACT_13705, GO:0060736=GO_REF:0000019, GO:0005506=GO_REF:0000002, GO:0070330=PMID:19129847, GO:0005783=GO_REF:0000054, GO:0008209=GO_REF:0000019, GO:0006703=Reactome:REACT_11037, GO:0009055=GO_REF:0000002, GO:0044281=Reactome:REACT_111217, GO:0016020=PMID:2848247, GO:0019825=PMID:2848247, GO:0005789=Reactome:REACT_9963, GO:0016712=PMID:1371509, GO:0016705=GO_REF:0000002, GO:0008202=Reactome:REACT_11057, GO:0020037=GO_REF:0000002} Q8IYJ7 CYP19A1 protein protein 20130413 {GO:0006694=TAS, GO:0006805=TAS, GO:0060736=IEA, GO:0005506=IEA, GO:0070330=IDA, GO:0005783=IDA, GO:0008209=IEA, GO:0006703=TAS, GO:0009055=IEA, GO:0044281=TAS, GO:0016020=TAS, GO:0019825=TAS, GO:0005789=TAS, GO:0016712=TAS, GO:0016705=IEA, GO:0008202=TAS, GO:0020037=IEA} androgen metabolic process, estrogen biosynthetic process, prostate gland growth, small molecule metabolic process, steroid biosynthetic process, steroid metabolic process, xenobiotic metabolic process endoplasmic reticulum, endoplasmic reticulum membrane, membrane aromatase activity, electron carrier activity, heme binding, iron ion binding, oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen, oxygen binding Human InterPro:IPR001128 CYP1A1 BHF-UCL UniProtKB {GO:0019369=Reactome:REACT_147851, GO:0014070=GO_REF:0000019, GO:0046685=GO_REF:0000019, GO:0006805=Reactome:REACT_13705, GO:0017144=PMID:19219744, GO:0017143=GO_REF:0000019, GO:0033189=GO_REF:0000019, GO:0009792=GO_REF:0000019, GO:0010041=GO_REF:0000019, GO:0016711=GO_REF:0000019, GO:0032496=GO_REF:0000019, GO:0070576=PMID:15546903, GO:0016712=GO_REF:0000002, GO:0046677=GO_REF:0000019, GO:0044255=Reactome:REACT_22279, GO:0005506=GO_REF:0000002, GO:0070330=GO_REF:0000003, GO:0042359=PMID:15546903, GO:0007568=GO_REF:0000019, GO:0060137=GO_REF:0000019, GO:0009635=GO_REF:0000019, GO:0006778=GO_REF:0000019, GO:0097267=Reactome:REACT_150134, GO:0055093=GO_REF:0000019, GO:0016491=PMID:19219744, GO:0005789=Reactome:REACT_150442, GO:0045750=GO_REF:0000019, GO:0019899=GO_REF:0000019, GO:0055114=PMID:19219744, GO:0020037=GO_REF:0000002, GO:0008283=GO_REF:0000019, GO:0044281=Reactome:REACT_111217, GO:0009624=GO_REF:0000019, GO:0050665=GO_REF:0000019, GO:0032094=GO_REF:0000019, GO:0019341=GO_REF:0000019, GO:0005739=GO_REF:0000019, GO:0043010=GO_REF:0000019, GO:0001666=GO_REF:0000019, GO:0019373=Reactome:REACT_150417, GO:0008395=GO_REF:0000019, GO:0042493=GO_REF:0000019, GO:0016679=GO_REF:0000019, GO:0009611=GO_REF:0000019, GO:0009055=GO_REF:0000002, GO:0009804=GO_REF:0000019, GO:0048565=GO_REF:0000019, GO:0009615=GO_REF:0000019, GO:0032451=GO_REF:0000019, GO:0009812=GO_REF:0000019, GO:0019825=PMID:1691986, GO:0042904=GO_REF:0000019, GO:0009308=GO_REF:0000019, GO:0070365=GO_REF:0000019} P04798 Cytochrome P450 1A1 protein 20090629 {GO:0019369=TAS, GO:0014070=IEA, GO:0046685=IEA, GO:0006805=TAS, GO:0017144=IDA, GO:0017143=IEA, GO:0033189=IEA, GO:0009792=IEA, GO:0010041=IEA, GO:0016711=IEA, GO:0032496=IEA, GO:0070576=IDA, GO:0016712=IEA, GO:0046677=IEA, GO:0044255=TAS, GO:0005506=IEA, GO:0070330=IEA, GO:0042359=IC, GO:0007568=IEA, GO:0060137=IEA, GO:0009635=IEA, GO:0006778=IEA, GO:0097267=TAS, GO:0055093=IEA, GO:0016491=IDA, GO:0005789=TAS, GO:0045750=IEA, GO:0019899=IEA, GO:0055114=IDA, GO:0020037=IEA, GO:0008283=IEA, GO:0044281=TAS, GO:0009624=IEA, GO:0050665=IEA, GO:0032094=IEA, GO:0019341=IEA, GO:0005739=IEA, GO:0043010=IEA, GO:0001666=IEA, GO:0019373=TAS, GO:0008395=IEA, GO:0042493=IEA, GO:0016679=IEA, GO:0009611=IEA, GO:0009055=IEA, GO:0009804=IEA, GO:0048565=IEA, GO:0009615=IEA, GO:0032451=IEA, GO:0009812=IEA, GO:0019825=TAS, GO:0042904=IEA, GO:0009308=IEA, GO:0070365=IEA} 9-cis-retinoic acid biosynthetic process, aging, amine metabolic process, arachidonic acid metabolic process, camera-type eye development, cell proliferation, cellular lipid metabolic process, coumarin metabolic process, dibenzo-p-dioxin catabolic process, digestive tract development, drug metabolic process, embryo development ending in birth or egg hatching, epoxygenase P450 pathway, flavonoid metabolic process, hepatocyte differentiation, hydrogen peroxide biosynthetic process, insecticide metabolic process, maternal process involved in parturition, omega-hydroxylase P450 pathway, oxidation-reduction process, porphyrin-containing compound metabolic process, positive regulation of S phase of mitotic cell cycle, response to antibiotic, response to arsenic-containing substance, response to drug, response to food, response to herbicide, response to hyperoxia, response to hypoxia, response to iron(III) ion, response to lipopolysaccharide, response to nematode, response to organic cyclic compound, response to virus, response to vitamin A, response to wounding, small molecule metabolic process, vitamin D metabolic process, xenobiotic metabolic process endoplasmic reticulum membrane, mitochondrion aromatase activity, demethylase activity, electron carrier activity, enzyme binding, flavonoid 3'-monooxygenase activity, heme binding, iron ion binding, oxidoreductase activity, oxidoreductase activity, acting on diphenols and related substances as donors, oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen, oxygen binding, steroid hydroxylase activity, vitamin D 24-hydroxylase activity Human GO:0070576 CYP1A2 BHF-UCL UniProtKB {GO:0010468=GO_REF:0000019, GO:0019369=Reactome:REACT_147851, GO:0034875=PMID:18619574, GO:0006706=PMID:18356043, GO:0006805=Reactome:REACT_13705, GO:0017144=PMID:15327587, GO:0030324=GO_REF:0000019, GO:0070989=PMID:18619574, GO:0071615=PMID:19029318, GO:0044281=Reactome:REACT_111217, GO:0050665=GO_REF:0000019, GO:0009791=GO_REF:0000019, GO:0032259=Reactome:REACT_6946, GO:0043231=PMID:2813353, GO:0004497=PMID:15327587, GO:0032787=PMID:19651758, GO:0009820=PMID:11511187, GO:0032496=GO_REF:0000019, GO:0016712=PMID:2813353, GO:0071276=GO_REF:0000019, GO:0032355=GO_REF:0000019, GO:0046483=PMID:15327587, GO:0070330=GO_REF:0000003, GO:0005506=GO_REF:0000002, GO:0019373=Reactome:REACT_150417, GO:0006950=GO_REF:0000019, GO:0009055=PMID:2813353, GO:0016098=PMID:16401082, GO:0018894=GO_REF:0000019, GO:0045333=GO_REF:0000019, GO:0032451=PMID:2813353, GO:0042737=PMID:18356043, GO:0006778=GO_REF:0000019, GO:0042738=PMID:18619574, GO:0097267=Reactome:REACT_150134, GO:0016491=PMID:16401082, GO:0005789=Reactome:REACT_150442, GO:0009403=PMID:11511187, GO:0019899=PMID:15680923, GO:0055114=PMID:16401082, GO:0020037=PMID:17311915} P05177 Cytochrome P450 1A2 protein 20100203 {GO:0010468=IEA, GO:0019369=TAS, GO:0034875=IDA, GO:0006706=IMP, GO:0006805=TAS, GO:0017144=IDA, GO:0030324=IEA, GO:0070989=IDA, GO:0071615=IDA, GO:0044281=TAS, GO:0050665=IEA, GO:0009791=IEA, GO:0032259=TAS, GO:0043231=IDA, GO:0004497=IDA, GO:0032787=IDA, GO:0009820=IDA, GO:0032496=IEA, GO:0016712=IMP, GO:0071276=IEA, GO:0032355=IEA, GO:0046483=IDA, GO:0070330=IEA, GO:0005506=IEA, GO:0019373=TAS, GO:0006950=IEA, GO:0009055=TAS, GO:0016098=IDA, GO:0018894=IEA, GO:0045333=IEA, GO:0032451=IDA, GO:0042737=IMP, GO:0006778=IEA, GO:0042738=IDA, GO:0097267=TAS, GO:0016491=IDA, GO:0005789=TAS, GO:0009403=IDA, GO:0019899=IPI, GO:0055114=IDA, GO:0020037=IDA} alkaloid metabolic process, arachidonic acid metabolic process, cellular respiration, cellular response to cadmium ion, dibenzo-p-dioxin metabolic process, drug catabolic process, drug metabolic process, epoxygenase P450 pathway, exogenous drug catabolic process, heterocycle metabolic process, hydrogen peroxide biosynthetic process, lung development, methylation, monocarboxylic acid metabolic process, monoterpenoid metabolic process, omega-hydroxylase P450 pathway, oxidation-reduction process, oxidative deethylation, oxidative demethylation, porphyrin-containing compound metabolic process, post-embryonic development, regulation of gene expression, response to estradiol stimulus, response to lipopolysaccharide, response to stress, small molecule metabolic process, steroid catabolic process, toxin biosynthetic process, xenobiotic metabolic process endoplasmic reticulum membrane, intracellular membrane-bounded organelle aromatase activity, caffeine oxidase activity, demethylase activity, electron carrier activity, enzyme binding, heme binding, iron ion binding, monooxygenase activity, oxidoreductase activity, oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen Human CYP1B1 Reactome UniProtKB {GO:0019369=Reactome:REACT_147851, GO:0006725=GO_REF:0000019, GO:0006805=Reactome:REACT_13705, GO:0005506=GO_REF:0000002, GO:0070330=GO_REF:0000003, GO:0019373=Reactome:REACT_150417, GO:0061298=GO_REF:0000019, GO:0009055=GO_REF:0000002, GO:0009636=GO_REF:0000019, GO:0071603=GO_REF:0000019, GO:0044281=Reactome:REACT_111217, GO:0001525=GO_REF:0000019, GO:0004497=PMID:9097971, GO:0019825=PMID:9097971, GO:0043542=GO_REF:0000019, GO:0097267=Reactome:REACT_150134, GO:0005789=Reactome:REACT_150442, GO:0016712=PMID:10871058, GO:0009404=GO_REF:0000019, GO:0007601=PMID:9097971, GO:0008202=PMID:22888116, GO:0020037=PMID:21147782, GO:0055114=PMID:9097971} Q16678 Cytochrome P450 1B1 protein 20130301 {GO:0019369=TAS, GO:0006725=IEA, GO:0006805=TAS, GO:0005506=IEA, GO:0070330=IEA, GO:0019373=TAS, GO:0061298=IEA, GO:0009055=IEA, GO:0009636=IEA, GO:0071603=IEA, GO:0044281=TAS, GO:0001525=IEA, GO:0004497=TAS, GO:0019825=TAS, GO:0043542=IEA, GO:0097267=TAS, GO:0005789=TAS, GO:0016712=IDA, GO:0009404=IEA, GO:0007601=TAS, GO:0008202=IDA, GO:0020037=IDA, GO:0055114=TAS} angiogenesis, arachidonic acid metabolic process, cellular aromatic compound metabolic process, endothelial cell migration, endothelial cell-cell adhesion, epoxygenase P450 pathway, omega-hydroxylase P450 pathway, oxidation-reduction process, response to toxic substance, retina vasculature development in camera-type eye, small molecule metabolic process, steroid metabolic process, toxin metabolic process, visual perception, xenobiotic metabolic process endoplasmic reticulum membrane aromatase activity, electron carrier activity, heme binding, iron ion binding, monooxygenase activity, oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen, oxygen binding Human CYP20A1 UniProtKB UniProtKB {GO:0004497=GO_REF:0000037, GO:0005506=GO_REF:0000002, GO:0009055=GO_REF:0000002, GO:0016021=GO_REF:0000037, GO:0016705=GO_REF:0000002, GO:0020037=GO_REF:0000002} Q6UW02 Cytochrome P450 20A1 protein 20130413 {GO:0004497=IEA, GO:0005506=IEA, GO:0009055=IEA, GO:0016021=IEA, GO:0016705=IEA, GO:0020037=IEA} integral to membrane electron carrier activity, heme binding, iron ion binding, monooxygenase activity, oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen Human UniProtKB-KW:KW-0812 CYP21A2 Reactome UniProtKB {GO:0006705=Reactome:REACT_11047, GO:0006805=Reactome:REACT_13705, GO:0005506=GO_REF:0000002, GO:0004509=GO_REF:0000003, GO:0008395=PMID:1406709, GO:0006704=Reactome:REACT_11036, GO:0009055=GO_REF:0000002, GO:0044281=Reactome:REACT_111217, GO:0005789=Reactome:REACT_10032, GO:0016705=GO_REF:0000002, GO:0005496=GO_REF:0000037, GO:0008202=Reactome:REACT_11057, GO:0020037=GO_REF:0000002} P08686 Steroid 21-hydroxylase protein 20130301 {GO:0006705=TAS, GO:0006805=TAS, GO:0005506=IEA, GO:0004509=IEA, GO:0008395=TAS, GO:0006704=TAS, GO:0009055=IEA, GO:0044281=TAS, GO:0005789=TAS, GO:0016705=IEA, GO:0005496=IEA, GO:0008202=TAS, GO:0020037=IEA} glucocorticoid biosynthetic process, mineralocorticoid biosynthetic process, small molecule metabolic process, steroid metabolic process, xenobiotic metabolic process endoplasmic reticulum membrane electron carrier activity, heme binding, iron ion binding, oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, steroid 21-monooxygenase activity, steroid binding, steroid hydroxylase activity Human CYP24A1 BHF-UCL UniProtKB {GO:0006805=Reactome:REACT_13705, GO:0005506=GO_REF:0000002, GO:0030342=PMID:8506296, GO:0042359=Reactome:REACT_13523, GO:0042369=PMID:16720713, GO:0005743=Reactome:REACT_13822, GO:0009055=GO_REF:0000002, GO:0033280=PMID:16720713, GO:0044281=Reactome:REACT_111217, GO:0001649=PMID:17023519, GO:0070561=PMID:16720713, GO:0006766=Reactome:REACT_13450, GO:0016491=PMID:7632726, GO:0008403=GO_REF:0000019, GO:0008202=Reactome:REACT_11057, GO:0055114=PMID:8506296, GO:0020037=PMID:8506296} Q07973 1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial protein 20090507 {GO:0006805=TAS, GO:0005506=IEA, GO:0030342=IDA, GO:0042359=TAS, GO:0042369=NAS, GO:0005743=TAS, GO:0009055=IEA, GO:0033280=IDA, GO:0044281=TAS, GO:0001649=IEP, GO:0070561=NAS, GO:0006766=TAS, GO:0016491=NAS, GO:0008403=IEA, GO:0008202=TAS, GO:0055114=IDA, GO:0020037=TAS} osteoblast differentiation, oxidation-reduction process, response to vitamin D, small molecule metabolic process, steroid metabolic process, vitamin D catabolic process, vitamin D metabolic process, vitamin D receptor signaling pathway, vitamin metabolic process, xenobiotic metabolic process mitochondrial inner membrane 1-alpha,25-dihydroxyvitamin D3 24-hydroxylase activity, 25-hydroxycholecalciferol-24-hydroxylase activity, electron carrier activity, heme binding, iron ion binding, oxidoreductase activity Human CYP26B1 BHF-UCL UniProtKB {GO:0006805=Reactome:REACT_13705, GO:0071300=GO_REF:0000019, GO:0005783=GO_REF:0000029, GO:0009954=GO_REF:0000024, GO:0030326=GO_REF:0000024, GO:0007283=GO_REF:0000024, GO:0044281=Reactome:REACT_111217, GO:2001037=GO_REF:0000019, GO:0005506=GO_REF:0000002, GO:0001709=GO_REF:0000024, GO:0009055=GO_REF:0000002, GO:0010628=GO_REF:0000019, GO:0048384=GO_REF:0000019, GO:0006766=Reactome:REACT_13450, GO:0048387=PMID:14532297, GO:0034653=PMID:10823918, GO:0060349=PMID:22019272, GO:0001972=PMID:10823918, GO:0008401=PMID:10823918, GO:0005789=Reactome:REACT_13550, GO:0016705=GO_REF:0000002, GO:0043587=GO_REF:0000019, GO:0007140=GO_REF:0000024, GO:0020037=PMID:10823918, GO:0055114=PMID:10823918} Q9NR63 Cytochrome P450 26B1 protein 20080902 {GO:0006805=TAS, GO:0071300=IEA, GO:0005783=NAS, GO:0009954=ISS, GO:0030326=ISS, GO:0007283=ISS, GO:0044281=TAS, GO:2001037=IEA, GO:0005506=IEA, GO:0001709=ISS, GO:0009055=IEA, GO:0010628=IEA, GO:0048384=IEA, GO:0006766=TAS, GO:0048387=TAS, GO:0034653=IDA, GO:0060349=IMP, GO:0001972=IDA, GO:0008401=IDA, GO:0005789=TAS, GO:0016705=IEA, GO:0043587=IEA, GO:0007140=ISS, GO:0020037=NAS, GO:0055114=IDA} bone morphogenesis, cell fate determination, cellular response to retinoic acid, embryonic limb morphogenesis, male meiosis, negative regulation of retinoic acid receptor signaling pathway, oxidation-reduction process, positive regulation of gene expression, positive regulation of tongue muscle cell differentiation, proximal/distal pattern formation, retinoic acid catabolic process, retinoic acid receptor signaling pathway, small molecule metabolic process, spermatogenesis, tongue morphogenesis, vitamin metabolic process, xenobiotic metabolic process endoplasmic reticulum, endoplasmic reticulum membrane electron carrier activity, heme binding, iron ion binding, oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, retinoic acid 4-hydroxylase activity, retinoic acid binding Human UniProtKB:Q811W2 CYP26C1 BHF-UCL UniProtKB {GO:0006805=Reactome:REACT_13705, GO:0005506=GO_REF:0000002, GO:0048284=GO_REF:0000024, GO:0009055=GO_REF:0000002, GO:0044281=Reactome:REACT_111217, GO:0009952=GO_REF:0000024, GO:0007417=GO_REF:0000024, GO:0014032=GO_REF:0000024, GO:0006766=Reactome:REACT_13450, GO:0048387=PMID:14532297, GO:0034653=PMID:14532297, GO:0001972=PMID:14532297, GO:0005789=Reactome:REACT_13793, GO:0008401=PMID:14532297, GO:0016021=GO_REF:0000037, GO:0055114=PMID:14532297, GO:0020037=GO_REF:0000002} Q6V0L0 Cytochrome P450 26C1 protein 20080902 {GO:0006805=TAS, GO:0005506=IEA, GO:0048284=ISS, GO:0009055=IEA, GO:0044281=TAS, GO:0009952=ISS, GO:0007417=ISS, GO:0014032=ISS, GO:0006766=TAS, GO:0048387=NAS, GO:0034653=IDA, GO:0001972=IDA, GO:0005789=TAS, GO:0008401=IDA, GO:0016021=IEA, GO:0055114=IDA, GO:0020037=IEA} anterior/posterior pattern specification, central nervous system development, negative regulation of retinoic acid receptor signaling pathway, neural crest cell development, organelle fusion, oxidation-reduction process, retinoic acid catabolic process, small molecule metabolic process, vitamin metabolic process, xenobiotic metabolic process endoplasmic reticulum membrane, integral to membrane electron carrier activity, heme binding, iron ion binding, retinoic acid 4-hydroxylase activity, retinoic acid binding Human CYP27A1 Reactome UniProtKB {GO:0006805=Reactome:REACT_13705, GO:0005506=GO_REF:0000002, GO:0030343=GO_REF:0000019, GO:0006699=Reactome:REACT_11054, GO:0008395=PMID:9790667, GO:0005743=GO_REF:0000019, GO:0009055=GO_REF:0000002, GO:0044281=Reactome:REACT_111217, GO:0031073=GO_REF:0000019, GO:0047749=GO_REF:0000003, GO:0005759=Reactome:REACT_10104, GO:0008206=Reactome:REACT_11040, GO:0016705=GO_REF:0000002, GO:0020037=GO_REF:0000002, GO:0008203=GO_REF:0000019} Q02318 Sterol 26-hydroxylase, mitochondrial protein 20130301 {GO:0006805=TAS, GO:0005506=IEA, GO:0030343=IEA, GO:0006699=TAS, GO:0008395=TAS, GO:0005743=IEA, GO:0009055=IEA, GO:0044281=TAS, GO:0031073=IEA, GO:0047749=IEA, GO:0005759=TAS, GO:0008206=TAS, GO:0016705=IEA, GO:0020037=IEA, GO:0008203=IEA} bile acid biosynthetic process, bile acid metabolic process, cholesterol metabolic process, small molecule metabolic process, xenobiotic metabolic process mitochondrial inner membrane, mitochondrial matrix cholestanetriol 26-monooxygenase activity, cholesterol 26-hydroxylase activity, electron carrier activity, heme binding, iron ion binding, oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, steroid hydroxylase activity, vitamin D3 25-hydroxylase activity Human CYP27B1 BHF-UCL UniProtKB {GO:0030308=PMID:12496369, GO:0043627=PMID:15795327, GO:0006805=Reactome:REACT_13705, GO:0008285=PMID:16549446, GO:0042368=PMID:16549446, GO:0042369=GO_REF:0000019, GO:0005741=Reactome:REACT_13628, GO:0033280=PMID:17426122, GO:0030282=PMID:17023519, GO:0044281=Reactome:REACT_111217, GO:0055074=PMID:9415400, GO:0005739=PMID:9333115, GO:0004498=PMID:9415400, GO:0046697=PMID:16720713, GO:0010980=PMID:16549446, GO:0005737=PMID:16720713, GO:0045618=PMID:12496369, GO:0032496=PMID:12855575, GO:0006816=GO_REF:0000024, GO:0034341=PMID:9282826, GO:0008202=Reactome:REACT_11057, GO:0030500=PMID:9415400, GO:0005506=GO_REF:0000002, GO:0042359=PMID:9415400, GO:0009055=GO_REF:0000002, GO:0070314=PMID:12496369, GO:0006766=Reactome:REACT_13450, GO:0034612=PMID:1690216, GO:0010956=PMID:16549446, GO:0070564=PMID:16549446, GO:0020037=GO_REF:0000002} O15528 25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial protein 20090624 {GO:0030308=IMP, GO:0043627=IEP, GO:0006805=TAS, GO:0008285=IDA, GO:0042368=IDA, GO:0042369=IEA, GO:0005741=TAS, GO:0033280=IEP, GO:0030282=IEP, GO:0044281=TAS, GO:0055074=IMP, GO:0005739=TAS, GO:0004498=IDA, GO:0046697=IEP, GO:0010980=IDA, GO:0005737=IDA, GO:0045618=IMP, GO:0032496=IEP, GO:0006816=ISS, GO:0034341=IDA, GO:0008202=TAS, GO:0030500=IMP, GO:0005506=IEA, GO:0042359=IDA, GO:0009055=IEA, GO:0070314=IMP, GO:0006766=TAS, GO:0034612=IEP, GO:0010956=IDA, GO:0070564=IDA, GO:0020037=IEA} G1 to G0 transition, bone mineralization, calcium ion homeostasis, calcium ion transport, decidualization, negative regulation of calcidiol 1-monooxygenase activity, negative regulation of cell growth, negative regulation of cell proliferation, positive regulation of keratinocyte differentiation, positive regulation of vitamin D 24-hydroxylase activity, positive regulation of vitamin D receptor signaling pathway, regulation of bone mineralization, response to estrogen stimulus, response to interferon-gamma, response to lipopolysaccharide, response to tumor necrosis factor, response to vitamin D, small molecule metabolic process, steroid metabolic process, vitamin D biosynthetic process, vitamin D catabolic process, vitamin D metabolic process, vitamin metabolic process, xenobiotic metabolic process cytoplasm, mitochondrial outer membrane, mitochondrion calcidiol 1-monooxygenase activity, electron carrier activity, heme binding, iron ion binding Human CYP27C1 UniProtKB UniProtKB {GO:0004497=GO_REF:0000037, GO:0016020=GO_REF:0000039, GO:0005506=GO_REF:0000002, GO:0009055=GO_REF:0000002, GO:0016705=GO_REF:0000002, GO:0020037=GO_REF:0000002} Q4G0S4 Cytochrome P450 27C1 protein 20130413 {GO:0004497=IEA, GO:0016020=IEA, GO:0005506=IEA, GO:0009055=IEA, GO:0016705=IEA, GO:0020037=IEA} membrane electron carrier activity, heme binding, iron ion binding, monooxygenase activity, oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen Human UniProtKB-SubCell:SL-0162 CYP2A6 BHF-UCL UniProtKB {GO:0005881=PMID:23264731, GO:0006805=Reactome:REACT_13705, GO:0005506=GO_REF:0000002, GO:0017144=PMID:19651758, GO:0009055=GO_REF:0000002, GO:0009804=PMID:19651758, GO:0008389=PMID:19029318, GO:0044281=Reactome:REACT_111217, GO:0046226=PMID:19029318, GO:0042738=PMID:15680923, GO:0005789=Reactome:REACT_572, GO:0016712=GO_REF:0000002, GO:0016705=GO_REF:0000002, GO:0019899=PMID:15680923, GO:0008202=PMID:18356043, GO:0020037=PMID:16086027} P11509 Cytochrome P450 2A6 protein 20100204 {GO:0005881=IDA, GO:0006805=TAS, GO:0005506=IEA, GO:0017144=IDA, GO:0009055=IEA, GO:0009804=IDA, GO:0008389=IDA, GO:0044281=TAS, GO:0046226=IDA, GO:0042738=IDA, GO:0005789=TAS, GO:0016712=IEA, GO:0016705=IEA, GO:0019899=IPI, GO:0008202=IMP, GO:0020037=IDA} coumarin catabolic process, coumarin metabolic process, drug metabolic process, exogenous drug catabolic process, small molecule metabolic process, steroid metabolic process, xenobiotic metabolic process cytoplasmic microtubule, endoplasmic reticulum membrane coumarin 7-hydroxylase activity, electron carrier activity, enzyme binding, heme binding, iron ion binding, oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen Human CYP2B6 BHF-UCL UniProtKB {GO:0006805=Reactome:REACT_13705, GO:0005506=GO_REF:0000002, GO:0017144=PMID:18356043, GO:0005783=GO_REF:0000029, GO:0009055=GO_REF:0000002, GO:0044281=Reactome:REACT_111217, GO:0043231=GO_REF:0000029, GO:0004497=PMID:19651758, GO:0042738=PMID:19029318, GO:0005789=Reactome:REACT_13515, GO:0016712=GO_REF:0000002, GO:0016705=GO_REF:0000002, GO:0042180=PMID:19651758, GO:0008202=PMID:18356043, GO:0020037=PMID:20061448, GO:0055114=PMID:19651758} P20813 Cytochrome P450 2B6 protein 20100204 {GO:0006805=TAS, GO:0005506=IEA, GO:0017144=IMP, GO:0005783=NAS, GO:0009055=IEA, GO:0044281=TAS, GO:0043231=NAS, GO:0004497=IDA, GO:0042738=IDA, GO:0005789=TAS, GO:0016712=IEA, GO:0016705=IEA, GO:0042180=IDA, GO:0008202=IMP, GO:0020037=IDA, GO:0055114=IDA} cellular ketone metabolic process, drug metabolic process, exogenous drug catabolic process, oxidation-reduction process, small molecule metabolic process, steroid metabolic process, xenobiotic metabolic process endoplasmic reticulum, endoplasmic reticulum membrane, intracellular membrane-bounded organelle electron carrier activity, heme binding, iron ion binding, monooxygenase activity, oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen Human CYP2C18 Reactome UniProtKB {GO:0004497=PMID:8110777, GO:0006805=Reactome:REACT_13705, GO:0019825=PMID:8110777, GO:0070330=GO_REF:0000003, GO:0005506=GO_REF:0000002, GO:0005789=Reactome:REACT_13729, GO:0009055=GO_REF:0000002, GO:0044281=Reactome:REACT_111217, GO:0020037=GO_REF:0000002} P33260 Cytochrome P450 2C18 protein 20130301 {GO:0004497=TAS, GO:0006805=TAS, GO:0019825=TAS, GO:0070330=IEA, GO:0005506=IEA, GO:0005789=TAS, GO:0009055=IEA, GO:0044281=TAS, GO:0020037=IEA} small molecule metabolic process, xenobiotic metabolic process endoplasmic reticulum membrane aromatase activity, electron carrier activity, heme binding, iron ion binding, monooxygenase activity, oxygen binding Human CYP2C19 BHF-UCL UniProtKB {GO:0019369=Reactome:REACT_147851, GO:0018676=GO_REF:0000003, GO:0006805=Reactome:REACT_13705, GO:0017144=PMID:19651758, GO:0005506=GO_REF:0000002, GO:0008395=PMID:18356043, GO:0018675=GO_REF:0000003, GO:0019373=Reactome:REACT_150417, GO:0009055=GO_REF:0000002, GO:0016098=PMID:16401082, GO:0052741=GO_REF:0000003, GO:0044281=Reactome:REACT_111217, GO:0043231=PMID:3442670, GO:0004497=PMID:19651758, GO:0019825=PMID:3442670, GO:0042738=PMID:19029318, GO:0097267=Reactome:REACT_150134, GO:0016491=PMID:16401082, GO:0005789=Reactome:REACT_150441, GO:0019899=PMID:15680923, GO:0008202=PMID:18356043, GO:0046483=PMID:19651758, GO:0055114=PMID:16401082, GO:0020037=PMID:23118231} P33261 Cytochrome P450 2C19 protein 20100204 {GO:0019369=TAS, GO:0018676=IEA, GO:0006805=TAS, GO:0017144=IDA, GO:0005506=IEA, GO:0008395=IMP, GO:0018675=IEA, GO:0019373=TAS, GO:0009055=IEA, GO:0016098=IDA, GO:0052741=IEA, GO:0044281=TAS, GO:0043231=TAS, GO:0004497=IDA, GO:0019825=TAS, GO:0042738=IDA, GO:0097267=TAS, GO:0016491=IDA, GO:0005789=TAS, GO:0019899=IPI, GO:0008202=IMP, GO:0046483=IDA, GO:0055114=IDA, GO:0020037=IDA} arachidonic acid metabolic process, drug metabolic process, epoxygenase P450 pathway, exogenous drug catabolic process, heterocycle metabolic process, monoterpenoid metabolic process, omega-hydroxylase P450 pathway, oxidation-reduction process, small molecule metabolic process, steroid metabolic process, xenobiotic metabolic process endoplasmic reticulum membrane, intracellular membrane-bounded organelle (R)-limonene 6-monooxygenase activity, (S)-limonene 6-monooxygenase activity, (S)-limonene 7-monooxygenase activity, electron carrier activity, enzyme binding, heme binding, iron ion binding, monooxygenase activity, oxidoreductase activity, oxygen binding, steroid hydroxylase activity Human CYP2C8 BHF-UCL UniProtKB {GO:0019369=Reactome:REACT_147851, GO:0034875=PMID:18619574, GO:0006805=Reactome:REACT_13705, GO:0017144=PMID:19651758, GO:0005506=GO_REF:0000002, GO:0070330=GO_REF:0000003, GO:0005783=GO_REF:0000029, GO:0019373=Reactome:REACT_150417, GO:0070989=PMID:18619574, GO:0009055=GO_REF:0000002, GO:0006082=PMID:19651758, GO:0044281=Reactome:REACT_111217, GO:0004497=PMID:19651758, GO:0042738=PMID:18619574, GO:0097267=Reactome:REACT_150134, GO:0005789=Reactome:REACT_150441, GO:0016705=GO_REF:0000002, GO:0055114=PMID:19651758, GO:0020037=GO_REF:0000002} P10632 Cytochrome P450 2C8 protein 20100203 {GO:0019369=TAS, GO:0034875=IDA, GO:0006805=TAS, GO:0017144=IDA, GO:0005506=IEA, GO:0070330=IEA, GO:0005783=NAS, GO:0019373=TAS, GO:0070989=IDA, GO:0009055=IEA, GO:0006082=IDA, GO:0044281=TAS, GO:0004497=IDA, GO:0042738=IDA, GO:0097267=TAS, GO:0005789=TAS, GO:0016705=IEA, GO:0055114=IDA, GO:0020037=IEA} arachidonic acid metabolic process, drug metabolic process, epoxygenase P450 pathway, exogenous drug catabolic process, omega-hydroxylase P450 pathway, organic acid metabolic process, oxidation-reduction process, oxidative demethylation, small molecule metabolic process, xenobiotic metabolic process endoplasmic reticulum, endoplasmic reticulum membrane aromatase activity, caffeine oxidase activity, electron carrier activity, heme binding, iron ion binding, monooxygenase activity, oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen Human CYP2C9 BHF-UCL UniProtKB {GO:0019369=Reactome:REACT_147851, GO:0034875=PMID:18619574, GO:0018676=GO_REF:0000003, GO:0006805=Reactome:REACT_13705, GO:0017144=PMID:19651758, GO:0005783=GO_REF:0000029, GO:0018675=GO_REF:0000003, GO:0070989=PMID:18619574, GO:0044281=Reactome:REACT_111217, GO:0043603=PMID:19651758, GO:0043231=PMID:3032244, GO:0004497=PMID:19651758, GO:0032787=PMID:19651758, GO:0008144=PMID:19448135, GO:0019627=PMID:19029318, GO:0008202=PMID:18356043, GO:0005506=GO_REF:0000002, GO:0019373=Reactome:REACT_150417, GO:0008395=PMID:18356043, GO:0009055=GO_REF:0000002, GO:0016098=PMID:16401082, GO:0052741=GO_REF:0000003, GO:0042737=PMID:18356043, GO:0042738=PMID:18619574, GO:0097267=Reactome:REACT_150134, GO:0005789=Reactome:REACT_150441, GO:0016491=PMID:16401082, GO:0020037=GO_REF:0000002, GO:0055114=PMID:16401082} P11712 Cytochrome P450 2C9 protein 20100203 {GO:0019369=TAS, GO:0034875=IDA, GO:0018676=IEA, GO:0006805=TAS, GO:0017144=IDA, GO:0005783=NAS, GO:0018675=IEA, GO:0070989=IDA, GO:0044281=TAS, GO:0043603=IDA, GO:0043231=TAS, GO:0004497=IDA, GO:0032787=IDA, GO:0008144=IDA, GO:0019627=IDA, GO:0008202=IMP, GO:0005506=IEA, GO:0019373=TAS, GO:0008395=IMP, GO:0009055=IEA, GO:0016098=IDA, GO:0052741=IEA, GO:0042737=IMP, GO:0042738=IDA, GO:0097267=TAS, GO:0005789=TAS, GO:0016491=IDA, GO:0020037=IEA, GO:0055114=IDA} arachidonic acid metabolic process, cellular amide metabolic process, drug catabolic process, drug metabolic process, epoxygenase P450 pathway, exogenous drug catabolic process, monocarboxylic acid metabolic process, monoterpenoid metabolic process, omega-hydroxylase P450 pathway, oxidation-reduction process, oxidative demethylation, small molecule metabolic process, steroid metabolic process, urea metabolic process, xenobiotic metabolic process endoplasmic reticulum, endoplasmic reticulum membrane, intracellular membrane-bounded organelle (R)-limonene 6-monooxygenase activity, (S)-limonene 6-monooxygenase activity, (S)-limonene 7-monooxygenase activity, caffeine oxidase activity, drug binding, electron carrier activity, heme binding, iron ion binding, monooxygenase activity, oxidoreductase activity, steroid hydroxylase activity Human CYP2D6 BHF-UCL UniProtKB {GO:0006805=PMID:19438707, GO:0017144=PMID:18356043, GO:0005783=PMID:19438707, GO:0070989=PMID:19438707, GO:0044281=Reactome:REACT_111217, GO:0005739=PMID:19438707, GO:0004497=PMID:15327587, GO:0009820=PMID:19651758, GO:0009822=PMID:15039299, GO:0008144=PMID:19448135, GO:0016712=GO_REF:0000002, GO:0008202=PMID:18356043, GO:0046483=PMID:15327587, GO:0033076=PMID:19448135, GO:0070330=GO_REF:0000003, GO:0005506=GO_REF:0000002, GO:0009055=GO_REF:0000002, GO:0009804=PMID:19438707, GO:0016098=PMID:16401082, GO:0051100=PMID:19448135, GO:0042737=PMID:15039299, GO:0016491=PMID:16401082, GO:0005789=Reactome:REACT_13478, GO:0090350=PMID:19448135, GO:0055114=PMID:16401082, GO:0020037=PMID:16352597} P10635 Cytochrome P450 2D6 protein 20100204 {GO:0006805=TAS, GO:0017144=IMP, GO:0005783=TAS, GO:0070989=IDA, GO:0044281=TAS, GO:0005739=IDA, GO:0004497=IDA, GO:0009820=IDA, GO:0009822=IDA, GO:0008144=IDA, GO:0016712=IEA, GO:0008202=IMP, GO:0046483=IDA, GO:0033076=IDA, GO:0070330=IEA, GO:0005506=IEA, GO:0009055=IEA, GO:0009804=IDA, GO:0016098=IDA, GO:0051100=IDA, GO:0042737=IDA, GO:0016491=IDA, GO:0005789=TAS, GO:0090350=IDA, GO:0055114=IDA, GO:0020037=IDA} alkaloid catabolic process, alkaloid metabolic process, coumarin metabolic process, drug catabolic process, drug metabolic process, heterocycle metabolic process, isoquinoline alkaloid metabolic process, monoterpenoid metabolic process, negative regulation of binding, negative regulation of cellular organofluorine metabolic process, oxidation-reduction process, oxidative demethylation, small molecule metabolic process, steroid metabolic process, xenobiotic metabolic process endoplasmic reticulum, endoplasmic reticulum membrane, mitochondrion aromatase activity, drug binding, electron carrier activity, heme binding, iron ion binding, monooxygenase activity, oxidoreductase activity, oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen Human CYP2E1 BHF-UCL UniProtKB {GO:0006805=Reactome:REACT_13705, GO:0017144=PMID:18356043, GO:0045471=GO_REF:0000019, GO:0031227=GO_REF:0000019, GO:0044281=Reactome:REACT_111217, GO:0005739=GO_REF:0000019, GO:0004497=PMID:19651758, GO:0016712=GO_REF:0000019, GO:0008202=PMID:18356043, GO:0046483=PMID:19651758, GO:0005506=GO_REF:0000002, GO:0042493=GO_REF:0000019, GO:0010193=GO_REF:0000019, GO:0010243=GO_REF:0000019, GO:0009055=GO_REF:0000002, GO:0016098=PMID:16401082, GO:0000139=GO_REF:0000019, GO:0019825=PMID:3233219, GO:0016709=PMID:18818195, GO:0005789=Reactome:REACT_1750, GO:0016491=PMID:16401082, GO:0006641=GO_REF:0000019, GO:0016705=GO_REF:0000002, GO:0019899=PMID:15680923, GO:0020037=PMID:18818195, GO:0055114=PMID:16401082} P05181 Cytochrome P450 2E1 protein 20100205 {GO:0006805=TAS, GO:0017144=IMP, GO:0045471=IEA, GO:0031227=IEA, GO:0044281=TAS, GO:0005739=IEA, GO:0004497=IDA, GO:0016712=IEA, GO:0008202=IMP, GO:0046483=IDA, GO:0005506=IEA, GO:0042493=IEA, GO:0010193=IEA, GO:0010243=IEA, GO:0009055=IEA, GO:0016098=IDA, GO:0000139=IEA, GO:0019825=TAS, GO:0016709=TAS, GO:0005789=TAS, GO:0016491=IDA, GO:0006641=IEA, GO:0016705=IEA, GO:0019899=IPI, GO:0020037=IDA, GO:0055114=IDA} drug metabolic process, heterocycle metabolic process, monoterpenoid metabolic process, oxidation-reduction process, response to drug, response to ethanol, response to organic nitrogen, response to ozone, small molecule metabolic process, steroid metabolic process, triglyceride metabolic process, xenobiotic metabolic process Golgi membrane, endoplasmic reticulum membrane, intrinsic to endoplasmic reticulum membrane, mitochondrion electron carrier activity, enzyme binding, heme binding, iron ion binding, monooxygenase activity, oxidoreductase activity, oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen, oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen, oxygen binding Human UniProtKB:P00167 CYP2J2 BHF-UCL UniProtKB {GO:0019369=Reactome:REACT_147851, GO:0008392=PMID:11901223, GO:0006805=PMID:11901223, GO:0005506=GO_REF:0000002, GO:0070330=GO_REF:0000003, GO:0019373=PMID:11901223, GO:0008016=PMID:8631948, GO:0009055=GO_REF:0000002, GO:0071614=PMID:11901223, GO:0044281=Reactome:REACT_111217, GO:0006690=PMID:8631948, GO:0043651=PMID:11901223, GO:0005789=Reactome:REACT_150442, GO:0008405=PMID:11901223, GO:0008404=PMID:11901223, GO:0020037=GO_REF:0000002} P51589 Cytochrome P450 2J2 protein 20100524 {GO:0019369=TAS, GO:0008392=IDA, GO:0006805=TAS, GO:0005506=IEA, GO:0070330=IEA, GO:0019373=IDA, GO:0008016=TAS, GO:0009055=IEA, GO:0071614=IDA, GO:0044281=TAS, GO:0006690=TAS, GO:0043651=IDA, GO:0005789=TAS, GO:0008405=IDA, GO:0008404=IDA, GO:0020037=IEA} arachidonic acid metabolic process, epoxygenase P450 pathway, icosanoid metabolic process, linoleic acid metabolic process, regulation of heart contraction, small molecule metabolic process, xenobiotic metabolic process endoplasmic reticulum membrane arachidonic acid 11,12-epoxygenase activity, arachidonic acid 14,15-epoxygenase activity, arachidonic acid epoxygenase activity, aromatase activity, electron carrier activity, heme binding, iron ion binding, linoleic acid epoxygenase activity Human CYP2S1 Reactome UniProtKB {GO:0004497=GO_REF:0000029, GO:0006805=Reactome:REACT_13705, GO:0070330=GO_REF:0000003, GO:0005506=GO_REF:0000002, GO:0005783=GO_REF:0000029, GO:0005789=Reactome:REACT_13626, GO:0009055=GO_REF:0000002, GO:0044281=Reactome:REACT_111217, GO:0016705=GO_REF:0000002, GO:0055114=GO_REF:0000029, GO:0020037=GO_REF:0000002} Q96SQ9 Cytochrome P450 2S1 protein 20130301 {GO:0004497=NAS, GO:0006805=TAS, GO:0070330=IEA, GO:0005506=IEA, GO:0005783=NAS, GO:0005789=TAS, GO:0009055=IEA, GO:0044281=TAS, GO:0016705=IEA, GO:0055114=NAS, GO:0020037=IEA} oxidation-reduction process, small molecule metabolic process, xenobiotic metabolic process endoplasmic reticulum, endoplasmic reticulum membrane aromatase activity, electron carrier activity, heme binding, iron ion binding, monooxygenase activity, oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen Human CYP2W1 Reactome UniProtKB {GO:0004497=GO_REF:0000037, GO:0006805=Reactome:REACT_13705, GO:0005506=GO_REF:0000002, GO:0005789=Reactome:REACT_13592, GO:0009055=GO_REF:0000002, GO:0044281=Reactome:REACT_111217, GO:0016705=GO_REF:0000002, GO:0020037=GO_REF:0000002} Q8TAV3 Cytochrome P450 2W1 protein 20130301 {GO:0004497=IEA, GO:0006805=TAS, GO:0005506=IEA, GO:0005789=TAS, GO:0009055=IEA, GO:0044281=TAS, GO:0016705=IEA, GO:0020037=IEA} small molecule metabolic process, xenobiotic metabolic process endoplasmic reticulum membrane electron carrier activity, heme binding, iron ion binding, monooxygenase activity, oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen Human CYP39A1 Reactome UniProtKB {GO:0006707=GO_REF:0000019, GO:0006805=Reactome:REACT_13705, GO:0005506=GO_REF:0000002, GO:0006699=Reactome:REACT_11054, GO:0008396=PMID:10748047, GO:0007586=PMID:10748047, GO:0009055=GO_REF:0000002, GO:0008387=GO_REF:0000019, GO:0044281=Reactome:REACT_111217, GO:0033782=GO_REF:0000003, GO:0043231=PMID:10748047, GO:0030573=GO_REF:0000037, GO:0005789=Reactome:REACT_10066, GO:0008206=Reactome:REACT_11040, GO:0020037=GO_REF:0000002} Q9NYL5 24-hydroxycholesterol 7-alpha-hydroxylase protein 20130301 {GO:0006707=IEA, GO:0006805=TAS, GO:0005506=IEA, GO:0006699=TAS, GO:0008396=IDA, GO:0007586=TAS, GO:0009055=IEA, GO:0008387=IEA, GO:0044281=TAS, GO:0033782=IEA, GO:0043231=TAS, GO:0030573=IEA, GO:0005789=TAS, GO:0008206=TAS, GO:0020037=IEA} bile acid biosynthetic process, bile acid catabolic process, bile acid metabolic process, cholesterol catabolic process, digestion, small molecule metabolic process, xenobiotic metabolic process endoplasmic reticulum membrane, intracellular membrane-bounded organelle 24-hydroxycholesterol 7alpha-hydroxylase activity, electron carrier activity, heme binding, iron ion binding, oxysterol 7-alpha-hydroxylase activity, steroid 7-alpha-hydroxylase activity Human CYP3A4 BHF-UCL UniProtKB {GO:0006629=PMID:2492107, GO:0034875=PMID:18619574, GO:0006706=PMID:18356043, GO:0006805=Reactome:REACT_13705, GO:0017144=PMID:15327587, GO:0030343=PMID:15546903, GO:0070989=PMID:18619574, GO:0044281=Reactome:REACT_111217, GO:0047638=GO_REF:0000003, GO:0050649=PMID:3259858, GO:0043231=PMID:3460094, GO:0004497=PMID:15327587, GO:0005737=PMID:18446064, GO:0009822=PMID:15039299, GO:0070576=PMID:15546903, GO:0016712=GO_REF:0000002, GO:0005496=PMID:15256616, GO:0008202=PMID:3259858, GO:0046483=PMID:15327587, GO:0009986=PMID:12493773, GO:0005506=PMID:15256616, GO:0042359=PMID:15546903, GO:0008209=PMID:19651758, GO:0008395=PMID:18356043, GO:0033780=GO_REF:0000003, GO:0009055=GO_REF:0000002, GO:0016098=PMID:16401082, GO:0042737=PMID:18356043, GO:0019825=PMID:3460094, GO:0042738=PMID:18619574, GO:0005789=Reactome:REACT_13765, GO:0016491=PMID:16401082, GO:0050591=GO_REF:0000003, GO:0016021=GO_REF:0000037, GO:0016705=GO_REF:0000002, GO:0019899=PMID:15680923, GO:0020037=GO_REF:0000002, GO:0055114=PMID:16401082} P08684 Cytochrome P450 3A4 protein 20100203 {GO:0006629=TAS, GO:0034875=IDA, GO:0006706=IMP, GO:0006805=TAS, GO:0017144=IDA, GO:0030343=IDA, GO:0070989=IDA, GO:0044281=TAS, GO:0047638=IEA, GO:0050649=IMP, GO:0043231=TAS, GO:0004497=IDA, GO:0005737=IDA, GO:0009822=IDA, GO:0070576=IDA, GO:0016712=IEA, GO:0005496=IDA, GO:0008202=IMP, GO:0046483=IDA, GO:0009986=IDA, GO:0005506=IDA, GO:0042359=IC, GO:0008209=TAS, GO:0008395=IMP, GO:0033780=IEA, GO:0009055=IEA, GO:0016098=IDA, GO:0042737=IMP, GO:0019825=TAS, GO:0042738=IDA, GO:0005789=TAS, GO:0016491=IDA, GO:0050591=IEA, GO:0016021=IEA, GO:0016705=IEA, GO:0019899=IPI, GO:0020037=IEA, GO:0055114=IDA} alkaloid catabolic process, androgen metabolic process, drug catabolic process, drug metabolic process, exogenous drug catabolic process, heterocycle metabolic process, lipid metabolic process, monoterpenoid metabolic process, oxidation-reduction process, oxidative demethylation, small molecule metabolic process, steroid catabolic process, steroid metabolic process, vitamin D metabolic process, xenobiotic metabolic process cell surface, cytoplasm, endoplasmic reticulum membrane, integral to membrane, intracellular membrane-bounded organelle albendazole monooxygenase activity, caffeine oxidase activity, electron carrier activity, enzyme binding, heme binding, iron ion binding, monooxygenase activity, oxidoreductase activity, oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen, oxygen binding, quinine 3-monooxygenase activity, steroid binding, steroid hydroxylase activity, taurochenodeoxycholate 6alpha-hydroxylase activity, testosterone 6-beta-hydroxylase activity, vitamin D 24-hydroxylase activity, vitamin D3 25-hydroxylase activity Human CYP3A5 BHF-UCL UniProtKB {GO:0006805=Reactome:REACT_13705, GO:0005506=GO_REF:0000002, GO:0070330=GO_REF:0000003, GO:0070989=PMID:15039299, GO:0009055=GO_REF:0000002, GO:0044281=Reactome:REACT_111217, GO:0043231=PMID:2732228, GO:0004497=GO_REF:0000024, GO:0042737=PMID:15039299, GO:0019825=PMID:2732228, GO:0009822=PMID:15039299, GO:0016491=PMID:15039299, GO:0005789=Reactome:REACT_13734, GO:0016712=GO_REF:0000002, GO:0008202=PMID:2732228, GO:0020037=GO_REF:0000002} P20815 Cytochrome P450 3A5 protein 20091105 {GO:0006805=TAS, GO:0005506=IEA, GO:0070330=IEA, GO:0070989=IDA, GO:0009055=IEA, GO:0044281=TAS, GO:0043231=TAS, GO:0004497=ISS, GO:0042737=IDA, GO:0019825=TAS, GO:0009822=IDA, GO:0016491=IDA, GO:0005789=TAS, GO:0016712=IEA, GO:0008202=TAS, GO:0020037=IEA} alkaloid catabolic process, drug catabolic process, oxidative demethylation, small molecule metabolic process, steroid metabolic process, xenobiotic metabolic process endoplasmic reticulum membrane, intracellular membrane-bounded organelle aromatase activity, electron carrier activity, heme binding, iron ion binding, monooxygenase activity, oxidoreductase activity, oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen, oxygen binding Human CYP4A11 GOC UniProtKB {GO:0019369=Reactome:REACT_147851, GO:0001676=PMID:18433732, GO:0006805=Reactome:REACT_13705, GO:0055078=PMID:10660572, GO:0044281=Reactome:REACT_111217, GO:0006691=PMID:9799565, GO:0036101=PMID:9799565, GO:0004497=GO_REF:0000038, GO:0006631=PMID:7679927, GO:0044255=Reactome:REACT_22279, GO:0008392=PMID:9618440, GO:0005506=GO_REF:0000002, GO:0019373=PMID:9618440, GO:0050051=PMID:9799565, GO:0018685=PMID:18433732, GO:0009055=GO_REF:0000002, GO:0052869=GO_REF:0000003, GO:0003091=PMID:10660572, GO:0003095=PMID:10660572, GO:0097267=Reactome:REACT_150134, GO:0032305=PMID:18391101, GO:0005789=Reactome:REACT_150441, GO:0016705=GO_REF:0000002, GO:0055114=PMID:18433732, GO:0020037=GO_REF:0000002} Q02928 Cytochrome P450 4A11 protein 20130413 {GO:0019369=TAS, GO:0001676=IDA, GO:0006805=TAS, GO:0055078=IEP, GO:0044281=TAS, GO:0006691=IDA, GO:0036101=IDA, GO:0004497=IEA, GO:0006631=TAS, GO:0044255=TAS, GO:0008392=IDA, GO:0005506=IEA, GO:0019373=IDA, GO:0050051=IDA, GO:0018685=IDA, GO:0009055=IEA, GO:0052869=IEA, GO:0003091=IEP, GO:0003095=IEP, GO:0097267=TAS, GO:0032305=IMP, GO:0005789=TAS, GO:0016705=IEA, GO:0055114=IDA, GO:0020037=IEA} arachidonic acid metabolic process, cellular lipid metabolic process, epoxygenase P450 pathway, fatty acid metabolic process, leukotriene B4 catabolic process, leukotriene metabolic process, long-chain fatty acid metabolic process, omega-hydroxylase P450 pathway, oxidation-reduction process, positive regulation of icosanoid secretion, pressure natriuresis, renal water homeostasis, small molecule metabolic process, sodium ion homeostasis, xenobiotic metabolic process endoplasmic reticulum membrane alkane 1-monooxygenase activity, arachidonic acid epoxygenase activity, arachidonic acid omega-hydroxylase activity, electron carrier activity, heme binding, iron ion binding, leukotriene-B4 20-monooxygenase activity, monooxygenase activity, oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen Human CYP4B1 UniProtKB UniProtKB {GO:0006805=Reactome:REACT_13705, GO:0005506=GO_REF:0000002, GO:0070330=GO_REF:0000003, GO:0009055=GO_REF:0000002, GO:0018879=GO_REF:0000019, GO:0044281=Reactome:REACT_111217, GO:0043231=GO_REF:0000019, GO:0004497=GO_REF:0000038, GO:0019825=PMID:2574990, GO:0042738=GO_REF:0000019, GO:0008144=GO_REF:0000019, GO:0018585=GO_REF:0000019, GO:0018917=GO_REF:0000019, GO:0005789=Reactome:REACT_13615, GO:0016705=GO_REF:0000002, GO:0020037=GO_REF:0000002} Q8IZB0 Pulmonary cytochrome P450 4B1 variant protein 20130413 {GO:0006805=TAS, GO:0005506=IEA, GO:0070330=IEA, GO:0009055=IEA, GO:0018879=IEA, GO:0044281=TAS, GO:0043231=IEA, GO:0004497=IEA, GO:0019825=TAS, GO:0042738=IEA, GO:0008144=IEA, GO:0018585=IEA, GO:0018917=IEA, GO:0005789=TAS, GO:0016705=IEA, GO:0020037=IEA} biphenyl metabolic process, exogenous drug catabolic process, fluorene metabolic process, small molecule metabolic process, xenobiotic metabolic process endoplasmic reticulum membrane, intracellular membrane-bounded organelle aromatase activity, drug binding, electron carrier activity, fluorene oxygenase activity, heme binding, iron ion binding, monooxygenase activity, oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, oxygen binding Human UniProtKB-KW:KW-0503 CYP4F11 Reactome UniProtKB {GO:0004497=GO_REF:0000029, GO:0006805=Reactome:REACT_13705, GO:0006954=PMID:10964514, GO:0070330=GO_REF:0000003, GO:0005506=GO_REF:0000002, GO:0005789=Reactome:REACT_13511, GO:0009055=GO_REF:0000002, GO:0044281=Reactome:REACT_111217, GO:0016021=GO_REF:0000037, GO:0016705=GO_REF:0000002, GO:0055114=PMID:10964514, GO:0020037=PMID:10964514} Q9HBI6 Cytochrome P450 4F11 protein 20130301 {GO:0004497=NAS, GO:0006805=TAS, GO:0006954=TAS, GO:0070330=IEA, GO:0005506=IEA, GO:0005789=TAS, GO:0009055=IEA, GO:0044281=TAS, GO:0016021=IEA, GO:0016705=IEA, GO:0055114=TAS, GO:0020037=TAS} inflammatory response, oxidation-reduction process, small molecule metabolic process, xenobiotic metabolic process endoplasmic reticulum membrane, integral to membrane aromatase activity, electron carrier activity, heme binding, iron ion binding, monooxygenase activity, oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen Human CYP4F12 Reactome UniProtKB {GO:0019369=GO_REF:0000024, GO:0000038=GO_REF:0000024, GO:0001676=GO_REF:0000024, GO:0006805=Reactome:REACT_13705, GO:0017144=GO_REF:0000024, GO:0044281=Reactome:REACT_111217, GO:0055078=GO_REF:0000024, GO:0043231=GO_REF:0000024, GO:0036101=GO_REF:0000024, GO:0005737=GO_REF:0000024, GO:0016324=GO_REF:0000024, GO:0042371=GO_REF:0000024, GO:0008392=GO_REF:0000024, GO:0070330=GO_REF:0000003, GO:0005506=GO_REF:0000002, GO:0019373=GO_REF:0000024, GO:0018685=GO_REF:0000024, GO:0050051=GO_REF:0000024, GO:0009055=GO_REF:0000002, GO:0003091=GO_REF:0000024, GO:0003095=GO_REF:0000024, GO:0030195=GO_REF:0000024, GO:0005789=Reactome:REACT_13485, GO:0016021=GO_REF:0000037, GO:0047057=GO_REF:0000024, GO:0042360=GO_REF:0000024, GO:0020037=GO_REF:0000002, GO:0055114=GO_REF:0000024} Q9HCS2 Cytochrome P450 4F12 protein 20130301 {GO:0019369=ISS, GO:0000038=ISS, GO:0001676=ISS, GO:0006805=TAS, GO:0017144=ISS, GO:0044281=TAS, GO:0055078=ISS, GO:0043231=ISS, GO:0036101=ISS, GO:0005737=ISS, GO:0016324=ISS, GO:0042371=ISS, GO:0008392=ISS, GO:0070330=IEA, GO:0005506=IEA, GO:0019373=ISS, GO:0018685=ISS, GO:0050051=ISS, GO:0009055=IEA, GO:0003091=ISS, GO:0003095=ISS, GO:0030195=ISS, GO:0005789=TAS, GO:0016021=IEA, GO:0047057=ISS, GO:0042360=ISS, GO:0020037=IEA, GO:0055114=ISS} arachidonic acid metabolic process, drug metabolic process, epoxygenase P450 pathway, leukotriene B4 catabolic process, long-chain fatty acid metabolic process, negative regulation of blood coagulation, oxidation-reduction process, pressure natriuresis, renal water homeostasis, small molecule metabolic process, sodium ion homeostasis, very long-chain fatty acid metabolic process, vitamin E metabolic process, vitamin K biosynthetic process, xenobiotic metabolic process apical plasma membrane, cytoplasm, endoplasmic reticulum membrane, integral to membrane, intracellular membrane-bounded organelle alkane 1-monooxygenase activity, arachidonic acid epoxygenase activity, aromatase activity, electron carrier activity, heme binding, iron ion binding, leukotriene-B4 20-monooxygenase activity, vitamin-K-epoxide reductase (warfarin-sensitive) activity Human CYP4F2 BHF-UCL UniProtKB {GO:0005515=PMID:17474147, GO:0019369=Reactome:REACT_147851, GO:0000038=PMID:18433732, GO:0001676=PMID:18433732, GO:0006805=Reactome:REACT_13705, GO:0052871=PMID:20861217, GO:0052872=PMID:20861217, GO:0044281=Reactome:REACT_111217, GO:0055078=PMID:10660572, GO:0006691=Reactome:REACT_150420, GO:0006690=Reactome:REACT_13645, GO:0043231=PMID:20861217, GO:0036101=PMID:8026587, GO:0004497=GO_REF:0000038, GO:0008392=PMID:20861217, GO:0005506=GO_REF:0000002, GO:0019373=PMID:20861217, GO:0018685=PMID:18433732, GO:0050051=PMID:8026587, GO:0009055=GO_REF:0000002, GO:0052869=PMID:10660572, GO:0003091=PMID:10660572, GO:0003095=PMID:10660572, GO:0030195=PMID:19297518, GO:0032304=PMID:18391101, GO:0097267=Reactome:REACT_150134, GO:0032305=PMID:17341693, GO:0005789=Reactome:REACT_150406, GO:0008217=PMID:18391101, GO:0016705=GO_REF:0000002, GO:0042360=PMID:20861217, GO:0055114=PMID:20861217, GO:0020037=GO_REF:0000002} P78329 Leukotriene-B(4) omega-hydroxylase 1 protein 20091102 {GO:0005515=IPI, GO:0019369=TAS, GO:0000038=IDA, GO:0001676=IDA, GO:0006805=TAS, GO:0052871=IDA, GO:0052872=IDA, GO:0044281=TAS, GO:0055078=IEP, GO:0006691=TAS, GO:0006690=TAS, GO:0043231=IDA, GO:0036101=IDA, GO:0004497=IEA, GO:0008392=IDA, GO:0005506=IEA, GO:0019373=IDA, GO:0018685=IDA, GO:0050051=IDA, GO:0009055=IEA, GO:0052869=IDA, GO:0003091=IEP, GO:0003095=IEP, GO:0030195=IMP, GO:0032304=IMP, GO:0097267=TAS, GO:0032305=IMP, GO:0005789=TAS, GO:0008217=IMP, GO:0016705=IEA, GO:0042360=IDA, GO:0055114=IDA, GO:0020037=IEA} arachidonic acid metabolic process, epoxygenase P450 pathway, icosanoid metabolic process, leukotriene B4 catabolic process, leukotriene metabolic process, long-chain fatty acid metabolic process, negative regulation of blood coagulation, negative regulation of icosanoid secretion, omega-hydroxylase P450 pathway, oxidation-reduction process, positive regulation of icosanoid secretion, pressure natriuresis, regulation of blood pressure, renal water homeostasis, small molecule metabolic process, sodium ion homeostasis, very long-chain fatty acid metabolic process, vitamin E metabolic process, xenobiotic metabolic process endoplasmic reticulum membrane, intracellular membrane-bounded organelle alkane 1-monooxygenase activity, alpha-tocopherol omega-hydroxylase activity, arachidonic acid epoxygenase activity, arachidonic acid omega-hydroxylase activity, electron carrier activity, heme binding, iron ion binding, leukotriene-B4 20-monooxygenase activity, monooxygenase activity, oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, protein binding, tocotrienol omega-hydroxylase activity Human CYP4F22 UniProtKB UniProtKB {GO:0004497=GO_REF:0000037, GO:0005506=GO_REF:0000002, GO:0005789=GO_REF:0000039, GO:0009055=GO_REF:0000002, GO:0016705=GO_REF:0000002, GO:0020037=GO_REF:0000002} Q6NT55 Cytochrome P450 4F22 protein 20130413 {GO:0004497=IEA, GO:0005506=IEA, GO:0005789=IEA, GO:0009055=IEA, GO:0016705=IEA, GO:0020037=IEA} endoplasmic reticulum membrane electron carrier activity, heme binding, iron ion binding, monooxygenase activity, oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen Human UniProtKB-SubCell:SL-0097 CYP4F3 Reactome UniProtKB {GO:0019369=Reactome:REACT_147851, GO:0052871=GO_REF:0000003, GO:0006805=Reactome:REACT_13705, GO:0005506=GO_REF:0000002, GO:0050051=GO_REF:0000003, GO:0009055=GO_REF:0000002, GO:0044281=Reactome:REACT_111217, GO:0006691=Reactome:REACT_150420, GO:0006690=Reactome:REACT_13645, GO:0004497=PMID:8486631, GO:0005789=Reactome:REACT_150394, GO:0016705=GO_REF:0000002, GO:0016021=GO_REF:0000037, GO:0020037=GO_REF:0000002} Q08477 Leukotriene-B(4) omega-hydroxylase 2 protein 20130301 {GO:0019369=TAS, GO:0052871=IEA, GO:0006805=TAS, GO:0005506=IEA, GO:0050051=IEA, GO:0009055=IEA, GO:0044281=TAS, GO:0006691=TAS, GO:0006690=TAS, GO:0004497=TAS, GO:0005789=TAS, GO:0016705=IEA, GO:0016021=IEA, GO:0020037=IEA} arachidonic acid metabolic process, icosanoid metabolic process, leukotriene metabolic process, small molecule metabolic process, xenobiotic metabolic process endoplasmic reticulum membrane, integral to membrane alpha-tocopherol omega-hydroxylase activity, electron carrier activity, heme binding, iron ion binding, leukotriene-B4 20-monooxygenase activity, monooxygenase activity, oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen Human CYP4F8 Reactome UniProtKB {GO:0006805=Reactome:REACT_13705, GO:0006693=PMID:10405341, GO:0070330=GO_REF:0000003, GO:0005506=GO_REF:0000002, GO:0005789=Reactome:REACT_13624, GO:0018685=PMID:10405341, GO:0009055=GO_REF:0000002, GO:0044281=Reactome:REACT_111217, GO:0016021=GO_REF:0000037, GO:0006690=Reactome:REACT_13645, GO:0020037=GO_REF:0000002} P98187 Cytochrome P450 4F8 protein 20130301 {GO:0006805=TAS, GO:0006693=TAS, GO:0070330=IEA, GO:0005506=IEA, GO:0005789=TAS, GO:0018685=TAS, GO:0009055=IEA, GO:0044281=TAS, GO:0016021=IEA, GO:0006690=TAS, GO:0020037=IEA} icosanoid metabolic process, prostaglandin metabolic process, small molecule metabolic process, xenobiotic metabolic process endoplasmic reticulum membrane, integral to membrane alkane 1-monooxygenase activity, aromatase activity, electron carrier activity, heme binding, iron ion binding Human CYP4V2 UniProtKB UniProtKB {GO:0004497=GO_REF:0000037, GO:0010430=PMID:19661213, GO:0005506=GO_REF:0000002, GO:0005789=GO_REF:0000039, GO:0009055=GO_REF:0000002, GO:0016021=GO_REF:0000037, GO:0016705=GO_REF:0000002, GO:0007601=GO_REF:0000037, GO:0050896=GO_REF:0000037, GO:0020037=GO_REF:0000002} Q6ZWL3 Cytochrome P450 4V2 protein 20110705 {GO:0004497=IEA, GO:0010430=IDA, GO:0005506=IEA, GO:0005789=IEA, GO:0009055=IEA, GO:0016021=IEA, GO:0016705=IEA, GO:0007601=IEA, GO:0050896=IEA, GO:0020037=IEA} fatty acid omega-oxidation, response to stimulus, visual perception endoplasmic reticulum membrane, integral to membrane electron carrier activity, heme binding, iron ion binding, monooxygenase activity, oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen Human CYP4X1 UniProtKB UniProtKB {GO:0070330=GO_REF:0000003, GO:0005506=GO_REF:0000002, GO:0005789=GO_REF:0000039, GO:0009055=GO_REF:0000002, GO:0016021=GO_REF:0000037, GO:0020037=GO_REF:0000002} Q8N118 Cytochrome P450 4X1 protein 20130413 {GO:0070330=IEA, GO:0005506=IEA, GO:0005789=IEA, GO:0009055=IEA, GO:0016021=IEA, GO:0020037=IEA} endoplasmic reticulum membrane, integral to membrane aromatase activity, electron carrier activity, heme binding, iron ion binding Human UniProtKB-SubCell:SL-0097 CYP51A1 Reactome UniProtKB {GO:0006695=Reactome:REACT_9405, GO:0006694=PMID:20149798, GO:0006805=Reactome:REACT_13705, GO:0005506=GO_REF:0000002, GO:0009055=GO_REF:0000002, GO:0008398=PMID:20149798, GO:0044281=Reactome:REACT_111217, GO:0033488=GO_REF:0000019, GO:0004497=GO_REF:0000038, GO:0005789=Reactome:REACT_147899, GO:0016705=GO_REF:0000002, GO:0016021=GO_REF:0000037, GO:0020037=PMID:20149798} Q16850 Lanosterol 14-alpha demethylase protein 20130301 {GO:0006695=TAS, GO:0006694=IDA, GO:0006805=TAS, GO:0005506=IEA, GO:0009055=IEA, GO:0008398=IDA, GO:0044281=TAS, GO:0033488=IEA, GO:0004497=IEA, GO:0005789=TAS, GO:0016705=IEA, GO:0016021=IEA, GO:0020037=IDA} cholesterol biosynthetic process, cholesterol biosynthetic process via 24,25-dihydrolanosterol, small molecule metabolic process, steroid biosynthetic process, xenobiotic metabolic process endoplasmic reticulum membrane, integral to membrane electron carrier activity, heme binding, iron ion binding, monooxygenase activity, oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, sterol 14-demethylase activity Human CYP7A1 Reactome UniProtKB {GO:0042632=GO_REF:0000024, GO:0006707=GO_REF:0000024, GO:0006805=Reactome:REACT_13705, GO:0005506=GO_REF:0000002, GO:0006699=Reactome:REACT_11054, GO:0009055=GO_REF:0000002, GO:0044281=Reactome:REACT_111217, GO:0043231=GO_REF:0000024, GO:0071397=GO_REF:0000024, GO:0070857=GO_REF:0000024, GO:0005789=Reactome:REACT_115550, GO:0008206=Reactome:REACT_11040, GO:0071333=PMID:19965590, GO:0008123=GO_REF:0000024, GO:0044255=Reactome:REACT_22279, GO:0020037=GO_REF:0000002} P22680 Cholesterol 7-alpha-monooxygenase protein 20130301 {GO:0042632=ISS, GO:0006707=ISS, GO:0006805=TAS, GO:0005506=IEA, GO:0006699=TAS, GO:0009055=IEA, GO:0044281=TAS, GO:0043231=ISS, GO:0071397=ISS, GO:0070857=ISS, GO:0005789=TAS, GO:0008206=TAS, GO:0071333=IDA, GO:0008123=ISS, GO:0044255=TAS, GO:0020037=IEA} bile acid biosynthetic process, bile acid metabolic process, cellular lipid metabolic process, cellular response to cholesterol, cellular response to glucose stimulus, cholesterol catabolic process, cholesterol homeostasis, regulation of bile acid biosynthetic process, small molecule metabolic process, xenobiotic metabolic process endoplasmic reticulum membrane, intracellular membrane-bounded organelle cholesterol 7-alpha-monooxygenase activity, electron carrier activity, heme binding, iron ion binding Human CYP7B1 Reactome UniProtKB {GO:0050679=GO_REF:0000019, GO:0008219=GO_REF:0000037, GO:0006805=Reactome:REACT_13705, GO:0005506=GO_REF:0000002, GO:0008396=GO_REF:0000019, GO:0006699=Reactome:REACT_11054, GO:0060740=GO_REF:0000019, GO:0009055=GO_REF:0000002, GO:0044281=Reactome:REACT_111217, GO:0005789=Reactome:REACT_9994, GO:0008206=Reactome:REACT_11040, GO:0033783=GO_REF:0000003, GO:0033147=GO_REF:0000019, GO:0020037=GO_REF:0000002, GO:0008203=GO_REF:0000037} O75881 25-hydroxycholesterol 7-alpha-hydroxylase protein 20130301 {GO:0050679=IEA, GO:0008219=IEA, GO:0006805=TAS, GO:0005506=IEA, GO:0008396=IEA, GO:0006699=TAS, GO:0060740=IEA, GO:0009055=IEA, GO:0044281=TAS, GO:0005789=TAS, GO:0008206=TAS, GO:0033783=IEA, GO:0033147=IEA, GO:0020037=IEA, GO:0008203=IEA} bile acid biosynthetic process, bile acid metabolic process, cell death, cholesterol metabolic process, negative regulation of intracellular estrogen receptor signaling pathway, positive regulation of epithelial cell proliferation, prostate gland epithelium morphogenesis, small molecule metabolic process, xenobiotic metabolic process endoplasmic reticulum membrane 25-hydroxycholesterol 7alpha-hydroxylase activity, electron carrier activity, heme binding, iron ion binding, oxysterol 7-alpha-hydroxylase activity Human CYP8B1 Reactome UniProtKB {GO:0006805=Reactome:REACT_13705, GO:0005506=GO_REF:0000002, GO:0008397=PMID:10051404, GO:0006699=Reactome:REACT_11054, GO:0009055=GO_REF:0000002, GO:0044281=Reactome:REACT_111217, GO:0004497=GO_REF:0000002, GO:0033778=GO_REF:0000003, GO:0019825=PMID:10051404, GO:0005789=Reactome:REACT_10071, GO:0008206=Reactome:REACT_11040, GO:0016705=GO_REF:0000002, GO:0016021=GO_REF:0000037, GO:0020037=GO_REF:0000002} Q9UNU6 7-alpha-hydroxycholest-4-en-3-one 12-alpha-hydroxylase protein 20130301 {GO:0006805=TAS, GO:0005506=IEA, GO:0008397=TAS, GO:0006699=TAS, GO:0009055=IEA, GO:0044281=TAS, GO:0004497=IEA, GO:0033778=IEA, GO:0019825=TAS, GO:0005789=TAS, GO:0008206=TAS, GO:0016705=IEA, GO:0016021=IEA, GO:0020037=IEA} bile acid biosynthetic process, bile acid metabolic process, small molecule metabolic process, xenobiotic metabolic process endoplasmic reticulum membrane, integral to membrane 7alpha-hydroxycholest-4-en-3-one 12alpha-hydroxylase activity, electron carrier activity, heme binding, iron ion binding, monooxygenase activity, oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, oxygen binding, sterol 12-alpha-hydroxylase activity Human CYR61 BHF-UCL UniProtKB {GO:0044319=PMID:20675382, GO:0060710=GO_REF:0000019, GO:0060591=GO_REF:0000019, GO:0008283=PMID:9135077, GO:0003181=GO_REF:0000019, GO:0010811=GO_REF:0000019, GO:0003281=GO_REF:0000019, GO:0002041=GO_REF:0000019, GO:0009653=PMID:9135077, GO:0001558=GO_REF:0000002, GO:0030513=PMID:20675382, GO:0006935=GO_REF:0000037, GO:0030198=GO_REF:0000019, GO:0045944=PMID:20675382, GO:0045860=PMID:20675382, GO:0060716=GO_REF:0000019, GO:0033690=PMID:20675382, GO:0070372=PMID:20675382, GO:0008201=GO_REF:0000037, GO:0005520=GO_REF:0000002, GO:0003278=GO_REF:0000019, GO:0043066=GO_REF:0000019, GO:0030335=PMID:20675382, GO:0043065=GO_REF:0000019, GO:2000304=GO_REF:0000019, GO:0060413=GO_REF:0000019, GO:0072593=GO_REF:0000019, GO:0050840=GO_REF:0000019, GO:0010518=GO_REF:0000019, GO:0005576=GO_REF:0000039, GO:0001649=GO_REF:0000019, GO:0045669=PMID:20675382, GO:0043280=GO_REF:0000019, GO:0005178=GO_REF:0000019, GO:0001934=PMID:20675382, GO:0061036=GO_REF:0000019} O00622 Protein CYR61 protein 20110414 {GO:0044319=IDA, GO:0060710=IEA, GO:0060591=IEA, GO:0008283=TAS, GO:0003181=IEA, GO:0010811=IEA, GO:0003281=IEA, GO:0002041=IEA, GO:0009653=TAS, GO:0001558=IEA, GO:0030513=IGI, GO:0006935=IEA, GO:0030198=IEA, GO:0045944=IDA, GO:0045860=IDA, GO:0060716=IEA, GO:0033690=IDA, GO:0070372=IDA, GO:0008201=IEA, GO:0005520=IEA, GO:0003278=IEA, GO:0043066=IEA, GO:0030335=IDA, GO:0043065=IEA, GO:2000304=IEA, GO:0060413=IEA, GO:0072593=IEA, GO:0050840=IEA, GO:0010518=IEA, GO:0005576=IEA, GO:0001649=IEA, GO:0045669=IDA, GO:0043280=IEA, GO:0005178=IEA, GO:0001934=IDA, GO:0061036=IEA} anatomical structure morphogenesis, apoptotic process involved in heart morphogenesis, atrial septum morphogenesis, atrioventricular valve morphogenesis, cell proliferation, chemotaxis, chondroblast differentiation, chorio-allantoic fusion, extracellular matrix organization, intussusceptive angiogenesis, labyrinthine layer blood vessel development, negative regulation of apoptotic process, osteoblast differentiation, positive regulation of BMP signaling pathway, positive regulation of apoptotic process, positive regulation of cartilage development, positive regulation of cell migration, positive regulation of cell-substrate adhesion, positive regulation of ceramide biosynthetic process, positive regulation of cysteine-type endopeptidase activity involved in apoptotic process, positive regulation of osteoblast differentiation, positive regulation of osteoblast proliferation, positive regulation of phospholipase activity, positive regulation of protein kinase activity, positive regulation of protein phosphorylation, positive regulation of transcription from RNA polymerase II promoter, reactive oxygen species metabolic process, regulation of ERK1 and ERK2 cascade, regulation of cell growth, ventricular septum development, wound healing, spreading of cells extracellular region extracellular matrix binding, heparin binding, insulin-like growth factor binding, integrin binding Human CYTH1 IntAct UniProtKB {GO:0005515=PMID:11867758, GO:0005802=GO_REF:0000033, GO:0090162=GO_REF:0000019, GO:0005086=GO_REF:0000033, GO:0005737=PMID:12606567, GO:0005543=GO_REF:0000002, GO:0005886=PMID:12606567, GO:0032012=GO_REF:0000002, GO:0005923=GO_REF:0000019, GO:0016192=GO_REF:0000033, GO:0030155=PMID:12606567} Q15438 Cytohesin-1 protein 20130415 {GO:0005515=IPI, GO:0005802=IBA, GO:0090162=IEA, GO:0005086=IBA, GO:0005737=IDA, GO:0005543=IEA, GO:0005886=IDA, GO:0032012=IEA, GO:0005923=IEA, GO:0016192=IBA, GO:0030155=IDA} establishment of epithelial cell polarity, regulation of ARF protein signal transduction, regulation of cell adhesion, vesicle-mediated transport cytoplasm, plasma membrane, tight junction, trans-Golgi network ARF guanyl-nucleotide exchange factor activity, phospholipid binding, protein binding Human UniProtKB:O60759 CYTH2 IntAct UniProtKB {GO:0005515=PMID:20946980, GO:0005802=GO_REF:0000033, GO:0005086=GO_REF:0000033, GO:0005737=PMID:17398095, GO:0030036=PMID:9417041, GO:0005543=GO_REF:0000002, GO:0016020=PMID:9417041, GO:0005886=PMID:17398095, GO:0032012=GO_REF:0000002, GO:0016192=GO_REF:0000033, GO:0030155=GO_REF:0000033, GO:0006897=PMID:9417041} Q99418 Cytohesin-2 protein 20130415 {GO:0005515=IPI, GO:0005802=IBA, GO:0005086=IBA, GO:0005737=IDA, GO:0030036=TAS, GO:0005543=IEA, GO:0016020=TAS, GO:0005886=IDA, GO:0032012=IEA, GO:0016192=IBA, GO:0030155=IBA, GO:0006897=TAS} actin cytoskeleton organization, endocytosis, regulation of ARF protein signal transduction, regulation of cell adhesion, vesicle-mediated transport cytoplasm, membrane, plasma membrane, trans-Golgi network ARF guanyl-nucleotide exchange factor activity, phospholipid binding, protein binding Human UniProtKB:P00533 CYTH3 GOC UniProtKB {GO:0090162=GO_REF:0000019, GO:0005802=GO_REF:0000033, GO:0005886=PMID:17398095, GO:0005220=PMID:9742223, GO:0048016=PMID:9742223, GO:0005547=GO_REF:0000019, GO:0001726=GO_REF:0000019, GO:0030155=GO_REF:0000033, GO:0045785=GO_REF:0000019, GO:0005086=GO_REF:0000033, GO:0005545=PMID:9742223, GO:0005737=GO_REF:0000019, GO:0005543=GO_REF:0000002, GO:0016020=PMID:9742223, GO:0032012=GO_REF:0000002, GO:0016192=GO_REF:0000033} O43739 Cytohesin-3 protein 20130413 {GO:0090162=IEA, GO:0005802=IBA, GO:0005886=IDA, GO:0005220=TAS, GO:0048016=TAS, GO:0005547=IEA, GO:0001726=IEA, GO:0030155=IBA, GO:0045785=IEA, GO:0005086=IBA, GO:0005545=TAS, GO:0005737=IEA, GO:0005543=IEA, GO:0016020=TAS, GO:0032012=IEA, GO:0016192=IBA} establishment of epithelial cell polarity, inositol phosphate-mediated signaling, positive regulation of cell adhesion, regulation of ARF protein signal transduction, regulation of cell adhesion, vesicle-mediated transport cytoplasm, membrane, plasma membrane, ruffle, trans-Golgi network 1-phosphatidylinositol binding, ARF guanyl-nucleotide exchange factor activity, inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity, phosphatidylinositol-3,4,5-trisphosphate binding, phospholipid binding Human CYTH4 UniProtKB UniProtKB {GO:0005802=GO_REF:0000033, GO:0005086=GO_REF:0000033, GO:0005543=GO_REF:0000002, GO:0005886=PMID:17398095, GO:0032012=GO_REF:0000002, GO:0016192=GO_REF:0000033, GO:0030155=GO_REF:0000033} Q9UIA0 Cytohesin-4 protein 20101220 {GO:0005802=IBA, GO:0005086=IBA, GO:0005543=IEA, GO:0005886=IDA, GO:0032012=IEA, GO:0016192=IBA, GO:0030155=IBA} regulation of ARF protein signal transduction, regulation of cell adhesion, vesicle-mediated transport plasma membrane, trans-Golgi network ARF guanyl-nucleotide exchange factor activity, phospholipid binding Human CYTIP HPA UniProtKB {GO:0005515=PMID:11867758, GO:0005737=GO_REF:0000052, GO:0030155=PMID:12606567, GO:0005938=PMID:12606567, GO:0005769=GO_REF:0000039} O60759 Cytohesin-interacting protein protein 20080818 {GO:0005515=IPI, GO:0005737=IDA, GO:0030155=IDA, GO:0005938=IDA, GO:0005769=IEA} regulation of cell adhesion cell cortex, cytoplasm, early endosome protein binding Human D2HGDH Reactome UniProtKB {GO:0008762=GO_REF:0000002, GO:0050660=GO_REF:0000002, GO:0044281=Reactome:REACT_111217, GO:0003824=GO_REF:0000002, GO:0010043=PMID:15070399, GO:0010042=PMID:15070399, GO:0051990=PMID:15070399, GO:0005739=PMID:15070399, GO:0051592=PMID:15070399, GO:0005759=Reactome:REACT_25270, GO:0006103=Reactome:REACT_25367, GO:0032026=PMID:15070399, GO:0032025=PMID:15070399, GO:0044267=PMID:15070399} Q8N465 D-2-hydroxyglutarate dehydrogenase, mitochondrial protein 20130301 {GO:0008762=IEA, GO:0050660=IEA, GO:0044281=TAS, GO:0003824=IEA, GO:0010043=ISS, GO:0010042=ISS, GO:0051990=ISS, GO:0005739=ISS, GO:0051592=ISS, GO:0005759=TAS, GO:0006103=TAS, GO:0032026=ISS, GO:0032025=ISS, GO:0044267=ISS} 2-oxoglutarate metabolic process, cellular protein metabolic process, response to calcium ion, response to cobalt ion, response to magnesium ion, response to manganese ion, response to zinc ion, small molecule metabolic process mitochondrial matrix, mitochondrion (R)-2-hydroxyglutarate dehydrogenase activity, UDP-N-acetylmuramate dehydrogenase activity, catalytic activity, flavin adenine dinucleotide binding Human DAAM1 HPA UniProtKB {GO:0005515=PMID:18218625, GO:0005737=GO_REF:0000052, GO:0030036=GO_REF:0000002, GO:0005886=GO_REF:0000052, GO:0017048=GO_REF:0000002, GO:0003779=GO_REF:0000037, GO:0042802=PMID:18218625} Q9Y4D1 Disheveled-associated activator of morphogenesis 1 protein 20101115 {GO:0005515=IPI, GO:0005737=IDA, GO:0030036=IEA, GO:0005886=IDA, GO:0017048=IEA, GO:0003779=IEA, GO:0042802=IPI} actin cytoskeleton organization cytoplasm, plasma membrane Rho GTPase binding, actin binding, identical protein binding, protein binding Human DAAM2 InterPro UniProtKB {GO:0030036=GO_REF:0000002, GO:0017048=GO_REF:0000002, GO:0003779=GO_REF:0000002} Q86T65 Disheveled-associated activator of morphogenesis 2 protein 20130413 {GO:0030036=IEA, GO:0017048=IEA, GO:0003779=IEA} actin cytoskeleton organization Rho GTPase binding, actin binding Human InterPro:IPR003104|InterPro:IPR010473 DAB1 ENSEMBL UniProtKB {GO:0048471=GO_REF:0000019, GO:0007264=GO_REF:0000019, GO:0021942=GO_REF:0000019, GO:0021517=GO_REF:0000019, GO:0005829=GO_REF:0000019, GO:0045860=GO_REF:0000019, GO:0007628=GO_REF:0000019, GO:0043025=GO_REF:0000019, GO:0051645=GO_REF:0000019, GO:0042493=GO_REF:0000019, GO:0014069=GO_REF:0000019, GO:0045177=GO_REF:0000019, GO:0021813=GO_REF:0000019, GO:0016358=GO_REF:0000019, GO:0046426=GO_REF:0000019, GO:0021589=GO_REF:0000019, GO:0005903=GO_REF:0000019, GO:0048712=GO_REF:0000019, GO:0007162=GO_REF:0000019, GO:0016020=GO_REF:0000019, GO:0045666=GO_REF:0000019, GO:0007494=GO_REF:0000019, GO:0050771=GO_REF:0000019, GO:0001764=GO_REF:0000019, GO:0043548=GO_REF:0000019} O75553 Disabled homolog 1 protein 20130413 {GO:0048471=IEA, GO:0007264=IEA, GO:0021942=IEA, GO:0021517=IEA, GO:0005829=IEA, GO:0045860=IEA, GO:0007628=IEA, GO:0043025=IEA, GO:0051645=IEA, GO:0042493=IEA, GO:0014069=IEA, GO:0045177=IEA, GO:0021813=IEA, GO:0016358=IEA, GO:0046426=IEA, GO:0021589=IEA, GO:0005903=IEA, GO:0048712=IEA, GO:0007162=IEA, GO:0016020=IEA, GO:0045666=IEA, GO:0007494=IEA, GO:0050771=IEA, GO:0001764=IEA, GO:0043548=IEA} Golgi localization, adult walking behavior, cell-cell adhesion involved in neuronal-glial interactions involved in cerebral cortex radial glia guided migration, cerebellum structural organization, dendrite development, midgut development, negative regulation of JAK-STAT cascade, negative regulation of astrocyte differentiation, negative regulation of axonogenesis, negative regulation of cell adhesion, neuron migration, positive regulation of neuron differentiation, positive regulation of protein kinase activity, radial glia guided migration of Purkinje cell, response to drug, small GTPase mediated signal transduction, ventral spinal cord development apical part of cell, brush border, cytosol, membrane, neuronal cell body, perinuclear region of cytoplasm, postsynaptic density phosphatidylinositol 3-kinase binding Human Ensembl:ENSMUSP00000102443 DAB2 BHF-UCL UniProtKB {GO:0005515=PMID:12805222, GO:0006907=GO_REF:0000019, GO:2000096=PMID:12805222, GO:0071560=GO_REF:0000019, GO:0046332=PMID:11387212, GO:0015031=GO_REF:0000037, GO:0005765=Reactome:REACT_10083, GO:0070022=PMID:11387212, GO:1900026=GO_REF:0000019, GO:0030099=GO_REF:0000019, GO:0016055=GO_REF:0000037, GO:2001046=GO_REF:0000019, GO:0030335=GO_REF:0000019, GO:0038024=PMID:16984970, GO:0005546=GO_REF:0000019, GO:0060766=PMID:16267015, GO:0001701=GO_REF:0000019, GO:0060391=PMID:11387212, GO:0005178=GO_REF:0000019, GO:0032968=GO_REF:0000019, GO:0045893=PMID:12805222, GO:0045892=PMID:12805222, GO:0016044=Reactome:REACT_11123, GO:0032091=PMID:12805222, GO:2000370=PMID:16984970, GO:0035615=PMID:16984970, GO:0030132=GO_REF:0000019, GO:0005886=Reactome:REACT_9971, GO:0008283=PMID:9620555, GO:0035612=GO_REF:0000019, GO:0010718=PMID:15734730, GO:0032436=PMID:12805222, GO:0005634=GO_REF:0000019, GO:0045807=PMID:21995445, GO:0016324=GO_REF:0000019, GO:0001921=GO_REF:0000019, GO:0090090=PMID:12805222, GO:0030511=PMID:11387212, GO:0007588=GO_REF:0000019, GO:0043066=PMID:15734730, GO:2000643=PMID:21995445, GO:0010862=PMID:11387212, GO:0006915=GO_REF:0000037, GO:0007257=GO_REF:0000019, GO:0008022=PMID:15837803, GO:0030665=GO_REF:0000039, GO:0005905=PMID:12857860, GO:0000904=GO_REF:0000019, GO:0007492=GO_REF:0000019, GO:0001934=PMID:12805222, GO:0048268=GO_REF:0000019} P98082 Disabled homolog 2 protein 20110110 {GO:0005515=IPI, GO:0006907=IEA, GO:2000096=IMP, GO:0071560=IEA, GO:0046332=IDA, GO:0015031=IEA, GO:0005765=TAS, GO:0070022=IDA, GO:1900026=IEA, GO:0030099=IEA, GO:0016055=IEA, GO:2001046=IEA, GO:0030335=IEA, GO:0038024=IMP, GO:0005546=IEA, GO:0060766=IMP, GO:0001701=IEA, GO:0060391=IDA, GO:0005178=IEA, GO:0032968=IEA, GO:0045893=IMP, GO:0045892=IMP, GO:0016044=TAS, GO:0032091=IMP, GO:2000370=IMP, GO:0035615=IMP, GO:0030132=IEA, GO:0005886=TAS, GO:0008283=TAS, GO:0035612=IEA, GO:0010718=IDA, GO:0032436=IMP, GO:0005634=IEA, GO:0045807=IMP, GO:0016324=IEA, GO:0001921=IEA, GO:0090090=IMP, GO:0030511=IDA, GO:0007588=IEA, GO:0043066=IDA, GO:2000643=IMP, GO:0010862=IDA, GO:0006915=IEA, GO:0007257=IEA, GO:0008022=IPI, GO:0030665=IEA, GO:0005905=IDA, GO:0000904=IEA, GO:0007492=IEA, GO:0001934=IMP, GO:0048268=IEA} Wnt receptor signaling pathway, activation of JUN kinase activity, apoptotic process, cell morphogenesis involved in differentiation, cell proliferation, cellular membrane organization, cellular response to transforming growth factor beta stimulus, clathrin coat assembly, endoderm development, excretion, in utero embryonic development, myeloid cell differentiation, negative regulation of androgen receptor signaling pathway, negative regulation of apoptotic process, negative regulation of canonical Wnt receptor signaling pathway, negative regulation of protein binding, negative regulation of transcription, DNA-dependent, pinocytosis, positive regulation of SMAD protein import into nucleus, positive regulation of Wnt receptor signaling pathway, planar cell polarity pathway, positive regulation of cell migration, positive regulation of clathrin-mediated endocytosis, positive regulation of early endosome to late endosome transport, positive regulation of endocytosis, positive regulation of epithelial to mesenchymal transition, positive regulation of integrin-mediated signaling pathway, positive regulation of pathway-restricted SMAD protein phosphorylation, positive regulation of proteasomal ubiquitin-dependent protein catabolic process, positive regulation of protein phosphorylation, positive regulation of receptor recycling, positive regulation of substrate adhesion-dependent cell spreading, positive regulation of transcription elongation from RNA polymerase II promoter, positive regulation of transcription, DNA-dependent, positive regulation of transforming growth factor beta receptor signaling pathway, protein transport apical plasma membrane, clathrin coat of coated pit, clathrin-coated vesicle membrane, coated pit, lysosomal membrane, nucleus, plasma membrane, transforming growth factor beta receptor homodimeric complex AP-2 adaptor complex binding, SMAD binding, cargo receptor activity, clathrin adaptor activity, integrin binding, phosphatidylinositol-4,5-bisphosphate binding, protein C-terminus binding, protein binding Human DAB2IP BHF-UCL UniProtKB {GO:0005515=PMID:19903888, GO:0030308=GO_REF:0000019, GO:0090129=GO_REF:0000024, GO:0050680=PMID:20154697, GO:0046330=PMID:19903888, GO:0070273=PMID:19948740, GO:0032403=PMID:19903888, GO:0042803=PMID:12813029, GO:0071158=PMID:19903888, GO:0046580=PMID:20154697, GO:0032312=GO_REF:0000024, GO:0043553=PMID:19903888, GO:1900744=GO_REF:0000024, GO:0071356=PMID:15310755, GO:0043025=GO_REF:0000024, GO:0070373=PMID:19903888, GO:0044257=PMID:17389591, GO:0034261=PMID:20154697, GO:0043122=GO_REF:0000024, GO:0034260=GO_REF:0000024, GO:0043124=PMID:15310755, GO:0019901=PMID:20080667, GO:0031235=GO_REF:0000033, GO:0042059=PMID:11812785, GO:0031434=PMID:17389591, GO:0031435=PMID:12813029, GO:0036324=GO_REF:0000024, GO:0005123=PMID:15310755, GO:0000122=PMID:15310755, GO:0014067=PMID:19903888, GO:0032266=PMID:19948740, GO:0010596=PMID:19033661, GO:0032320=GO_REF:0000033, GO:0070059=PMID:18281285, GO:0010976=GO_REF:0000024, GO:0071347=PMID:19948740, GO:0043184=PMID:19033661, GO:0045892=PMID:20080667, GO:0043548=PMID:19033661, GO:0030948=PMID:19033661, GO:0035662=PMID:19948740, GO:0030424=GO_REF:0000024, GO:0034144=PMID:19948740, GO:0045732=GO_REF:0000024, GO:0017124=PMID:19903888, GO:0035924=PMID:19033661, GO:0008285=PMID:19903888, GO:0071902=PMID:20080667, GO:0005886=PMID:15310755, GO:0071901=PMID:20154697, GO:2001235=PMID:19903888, GO:0048147=GO_REF:0000024, GO:0030139=PMID:19948740, GO:0010719=PMID:20080667, GO:0035414=GO_REF:0000024, GO:0071889=PMID:17389591, GO:0005737=GO_REF:0000052, GO:0000185=PMID:19903888, GO:0005543=GO_REF:0000002, GO:0043407=PMID:12813029, GO:0045944=PMID:15310755, GO:0043507=PMID:15310755, GO:0019900=PMID:17389591, GO:0051721=PMID:20080667, GO:0090090=PMID:20080667, GO:1900006=GO_REF:0000024, GO:0035591=PMID:20080667, GO:0043065=PMID:12813029, GO:0044301=GO_REF:0000024, GO:2001224=GO_REF:0000024, GO:0007252=GO_REF:0000024, GO:0035148=PMID:19033661, GO:0044300=GO_REF:0000024, GO:1990032=GO_REF:0000024, GO:0021814=GO_REF:0000024, GO:0032088=PMID:20154697, GO:0007257=PMID:12813029, GO:0070317=PMID:19903888, GO:0021819=GO_REF:0000024, GO:1900747=GO_REF:0000024, GO:0032809=GO_REF:0000024, GO:0036312=PMID:19903888, GO:0005099=GO_REF:0000024, GO:2000599=PMID:19903888, GO:1901800=PMID:20080667, GO:0047485=GO_REF:0000019, GO:0071222=PMID:19948740, GO:0071364=PMID:11812785, GO:0048812=GO_REF:0000024, GO:0016525=PMID:19033661, GO:0043254=PMID:19948740, GO:0001933=PMID:20080667, GO:0043410=PMID:19903888, GO:0010633=PMID:20080667} Q5VWQ8 Disabled homolog 2-interacting protein protein 20101119 {GO:0005515=IPI, GO:0030308=IEA, GO:0090129=ISS, GO:0050680=IMP, GO:0046330=IDA, GO:0070273=IDA, GO:0032403=IDA, GO:0042803=IPI, GO:0071158=IDA, GO:0046580=IC, GO:0032312=ISS, GO:0043553=IDA, GO:1900744=ISS, GO:0071356=IDA, GO:0043025=ISS, GO:0070373=IDA, GO:0044257=IDA, GO:0034261=IMP, GO:0043122=ISS, GO:0034260=ISS, GO:0043124=IDA, GO:0019901=IPI, GO:0031235=IBA, GO:0042059=ISS, GO:0031434=IPI, GO:0031435=IPI, GO:0036324=ISS, GO:0005123=IPI, GO:0000122=IDA, GO:0014067=IDA, GO:0032266=IDA, GO:0010596=IMP, GO:0032320=IBA, GO:0070059=ISS, GO:0010976=ISS, GO:0071347=IDA, GO:0043184=IPI, GO:0045892=IMP, GO:0043548=IDA, GO:0030948=IMP, GO:0035662=IDA, GO:0030424=ISS, GO:0034144=IDA, GO:0045732=ISS, GO:0017124=IDA, GO:0035924=IDA, GO:0008285=IDA, GO:0071902=IMP, GO:0005886=IDA, GO:0071901=IMP, GO:2001235=IDA, GO:0048147=ISS, GO:0030139=IDA, GO:0010719=IMP, GO:0035414=ISS, GO:0071889=IDA, GO:0005737=IDA, GO:0000185=IDA, GO:0005543=IEA, GO:0043407=IDA, GO:0045944=IDA, GO:0043507=IDA, GO:0019900=IPI, GO:0051721=IDA, GO:0090090=IMP, GO:1900006=ISS, GO:0035591=IDA, GO:0043065=IDA, GO:0044301=ISS, GO:2001224=ISS, GO:0007252=ISS, GO:0035148=IMP, GO:0044300=ISS, GO:1990032=ISS, GO:0021814=ISS, GO:0032088=IMP, GO:0007257=IDA, GO:0070317=IDA, GO:0021819=ISS, GO:1900747=ISS, GO:0032809=ISS, GO:0036312=IDA, GO:0005099=ISS, GO:2000599=IDA, GO:1901800=IMP, GO:0047485=IEA, GO:0071222=IDA, GO:0071364=ISS, GO:0048812=ISS, GO:0016525=IDA, GO:0043254=IDA, GO:0001933=IMP, GO:0043410=IDA, GO:0010633=TAS} I-kappaB phosphorylation, activation of JUN kinase activity, activation of MAPKKK activity, cell motility involved in cerebral cortex radial glia guided migration, cellular protein catabolic process, cellular response to epidermal growth factor stimulus, cellular response to interleukin-1, cellular response to lipopolysaccharide, cellular response to tumor necrosis factor, cellular response to vascular endothelial growth factor stimulus, intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress, layer formation in cerebral cortex, negative regulation of ERK1 and ERK2 cascade, negative regulation of G0 to G1 transition, negative regulation of GTPase activity, negative regulation of I-kappaB kinase/NF-kappaB cascade, negative regulation of MAP kinase activity, negative regulation of NF-kappaB transcription factor activity, negative regulation of Ras GTPase activity, negative regulation of Ras protein signal transduction, negative regulation of angiogenesis, negative regulation of canonical Wnt receptor signaling pathway, negative regulation of catenin import into nucleus, negative regulation of cell growth, negative regulation of cell proliferation, negative regulation of cyclin catabolic process, negative regulation of endothelial cell migration, negative regulation of epidermal growth factor receptor signaling pathway, negative regulation of epithelial cell migration, negative regulation of epithelial cell proliferation, negative regulation of epithelial to mesenchymal transition, negative regulation of fibroblast proliferation, negative regulation of phosphatidylinositol 3-kinase activity, negative regulation of phosphatidylinositol 3-kinase cascade, negative regulation of protein phosphorylation, negative regulation of protein serine/threonine kinase activity, negative regulation of toll-like receptor 4 signaling pathway, negative regulation of transcription from RNA polymerase II promoter, negative regulation of transcription, DNA-dependent, negative regulation of vascular endothelial growth factor receptor signaling pathway, negative regulation of vascular endothelial growth factor signaling pathway, neuron projection morphogenesis, positive regulation of JNK cascade, positive regulation of JUN kinase activity, positive regulation of MAPK cascade, positive regulation of Ras GTPase activity, positive regulation of apoptotic process, positive regulation of apoptotic signaling pathway, positive regulation of cell cycle arrest, positive regulation of dendrite development, positive regulation of neuron migration, positive regulation of neuron projection development, positive regulation of proteasomal protein catabolic process, positive regulation of protein catabolic process, positive regulation of protein serine/threonine kinase activity, positive regulation of synapse maturation, positive regulation of transcription from RNA polymerase II promoter, regulation of ARF GTPase activity, regulation of I-kappaB kinase/NF-kappaB cascade, regulation of p38MAPK cascade, regulation of protein complex assembly, tube formation, vascular endothelial growth factor receptor-2 signaling pathway axon, cerebellar mossy fiber, climbing fiber, cytoplasm, endocytic vesicle, intrinsic to internal side of plasma membrane, neuronal cell body, neuronal cell body membrane, parallel fiber, plasma membrane 14-3-3 protein binding, Ras GTPase activator activity, SH3 domain binding, Toll-like receptor 4 binding, death receptor binding, kinase binding, mitogen-activated protein kinase kinase binding, mitogen-activated protein kinase kinase kinase binding, phosphatidylinositol 3-kinase binding, phosphatidylinositol 3-kinase regulatory subunit binding, phosphatidylinositol-3-phosphate binding, phosphatidylinositol-4-phosphate binding, phospholipid binding, protein N-terminus binding, protein binding, protein complex binding, protein homodimerization activity, protein kinase binding, protein phosphatase 2A binding, signaling adaptor activity, vascular endothelial growth factor receptor 2 binding Human DACH1 HPA UniProtKB {GO:0046545=GO_REF:0000019, GO:0005515=PMID:20956529, GO:0005667=GO_REF:0000019, GO:0030336=PMID:20956529, GO:0007585=GO_REF:0000019, GO:0008283=GO_REF:0000019, GO:0005730=GO_REF:0000052, GO:0048147=GO_REF:0000019, GO:0060244=GO_REF:0000019, GO:0005634=GO_REF:0000052, GO:0003677=GO_REF:0000037, GO:0001078=PMID:20956529, GO:0005737=GO_REF:0000019, GO:0010944=PMID:20956529, GO:0001967=GO_REF:0000019, GO:0000166=GO_REF:0000002, GO:0001075=GO_REF:0000019} Q9UI36 Dachshund homolog 1 protein 20101115 {GO:0046545=IEA, GO:0005515=IPI, GO:0005667=IEA, GO:0030336=IDA, GO:0007585=IEA, GO:0008283=IEA, GO:0005730=IDA, GO:0048147=IEA, GO:0060244=IEA, GO:0005634=IDA, GO:0003677=IEA, GO:0001078=IDA, GO:0005737=IEA, GO:0010944=IMP, GO:0001967=IEA, GO:0000166=IEA, GO:0001075=IEA} cell proliferation, development of primary female sexual characteristics, negative regulation of cell migration, negative regulation of cell proliferation involved in contact inhibition, negative regulation of fibroblast proliferation, negative regulation of transcription by competitive promoter binding, respiratory gaseous exchange, suckling behavior cytoplasm, nucleolus, nucleus, transcription factor complex DNA binding, RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription, RNA polymerase II core promoter sequence-specific DNA binding transcription factor activity involved in preinitiation complex assembly, nucleotide binding, protein binding Human DACH2 HPA UniProtKB {GO:0046545=GO_REF:0000019, GO:0006355=GO_REF:0000037, GO:0000166=GO_REF:0000002, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q96NX9 Dachshund homolog 2 protein 20101115 {GO:0046545=IEA, GO:0006355=IEA, GO:0000166=IEA, GO:0005730=IDA, GO:0005634=IDA, GO:0003677=IEA, GO:0006351=IEA} development of primary female sexual characteristics, regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleolus, nucleus DNA binding, nucleotide binding NOT Human DACT1 IntAct UniProtKB {GO:0005515=PMID:22470507, GO:0045732=PMID:16446366, GO:0030054=GO_REF:0000037, GO:0008013=PMID:22470507, GO:0030178=PMID:16446366, GO:0030877=PMID:22470507, GO:0045202=GO_REF:0000039, GO:2000095=GO_REF:0000024, GO:0030177=PMID:21262972, GO:0005634=GO_REF:0000039, GO:0035413=PMID:15580286, GO:0035412=PMID:18936100, GO:1900107=PMID:17197390, GO:0005737=PMID:16446366, GO:0046329=PMID:17197390, GO:0031647=PMID:21262972, GO:0005080=GO_REF:0000024, GO:0016055=GO_REF:0000037, GO:0051018=PMID:21262972, GO:0090090=GO_REF:0000019, GO:0070097=GO_REF:0000024, GO:2000134=PMID:18936100, GO:0000122=PMID:18936100, GO:0001702=GO_REF:0000019, GO:0048813=GO_REF:0000019, GO:0050808=GO_REF:0000019, GO:0048619=GO_REF:0000024, GO:0045600=GO_REF:0000019} Q9NYF0 Dapper homolog 1 protein 20130415 {GO:0005515=IPI, GO:0045732=IDA, GO:0030054=IEA, GO:0008013=IDA, GO:0030178=IGI, GO:0030877=IDA, GO:0045202=IEA, GO:2000095=ISS, GO:0030177=IDA, GO:0005634=IEA, GO:0035413=IMP, GO:0035412=IMP, GO:1900107=IDA, GO:0005737=IDA, GO:0046329=IDA, GO:0031647=IDA, GO:0005080=ISS, GO:0016055=IEA, GO:0051018=IDA, GO:0090090=IEA, GO:0070097=ISS, GO:2000134=IDA, GO:0000122=IDA, GO:0001702=IEA, GO:0048813=IEA, GO:0050808=IEA, GO:0048619=ISS, GO:0045600=IEA} Wnt receptor signaling pathway, dendrite morphogenesis, embryonic hindgut morphogenesis, gastrulation with mouth forming second, negative regulation of G1/S transition of mitotic cell cycle, negative regulation of JNK cascade, negative regulation of Wnt receptor signaling pathway, negative regulation of canonical Wnt receptor signaling pathway, negative regulation of transcription from RNA polymerase II promoter, positive regulation of Wnt receptor signaling pathway, positive regulation of catenin import into nucleus, positive regulation of fat cell differentiation, positive regulation of protein catabolic process, regulation of Wnt receptor signaling pathway, planar cell polarity pathway, regulation of catenin import into nucleus, regulation of nodal signaling pathway, regulation of protein stability, synapse organization beta-catenin destruction complex, cell junction, cytoplasm, nucleus, synapse beta-catenin binding, delta-catenin binding, protein binding, protein kinase A binding, protein kinase C binding Human UniProtKB:P49841 DACT2 UniProtKB UniProtKB {GO:0003382=GO_REF:0000024, GO:1900108=GO_REF:0000024, GO:0005739=GO_REF:0000019, GO:0007162=GO_REF:0000024, GO:0070097=GO_REF:0000024, GO:0008013=GO_REF:0000024, GO:0072061=GO_REF:0000024, GO:0005080=GO_REF:0000024, GO:0043588=GO_REF:0000024, GO:0051018=GO_REF:0000024, GO:0008134=GO_REF:0000024} Q5SW24 Dapper homolog 2 protein 20120730 {GO:0003382=ISS, GO:1900108=ISS, GO:0005739=IEA, GO:0007162=ISS, GO:0070097=ISS, GO:0008013=ISS, GO:0072061=ISS, GO:0005080=ISS, GO:0043588=ISS, GO:0051018=ISS, GO:0008134=ISS} epithelial cell morphogenesis, inner medullary collecting duct development, negative regulation of cell adhesion, negative regulation of nodal signaling pathway, skin development mitochondrion beta-catenin binding, delta-catenin binding, protein kinase A binding, protein kinase C binding, transcription factor binding Human UniProtKB:Q7TN08 DACT3 UniProtKB UniProtKB {GO:0030308=PMID:18538736, GO:0070097=GO_REF:0000024, GO:0005080=GO_REF:0000024, GO:0030178=PMID:18538736, GO:0051018=GO_REF:0000024, GO:0016055=GO_REF:0000037, GO:0035414=PMID:18538736} Q96B18 Dapper homolog 3 protein 20120730 {GO:0030308=IDA, GO:0070097=ISS, GO:0005080=ISS, GO:0030178=IDA, GO:0051018=ISS, GO:0016055=IEA, GO:0035414=IDA} Wnt receptor signaling pathway, negative regulation of Wnt receptor signaling pathway, negative regulation of catenin import into nucleus, negative regulation of cell growth delta-catenin binding, protein kinase A binding, protein kinase C binding Human UniProtKB:Q0PHV7 DAD1 Reactome UniProtKB {GO:0004576=GO_REF:0000024, GO:0043066=GO_REF:0000019, GO:0007584=GO_REF:0000019, GO:0042493=GO_REF:0000019, GO:0001824=GO_REF:0000019, GO:0006915=GO_REF:0000037, GO:0004579=PMID:15835887, GO:0005789=Reactome:REACT_22208, GO:0006486=GO_REF:0000024, GO:0016021=GO_REF:0000037, GO:0008250=PMID:15835887, GO:0044267=Reactome:REACT_17015, GO:0018279=Reactome:REACT_22426, GO:0043687=Reactome:REACT_22161} P61803 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1 protein 20130213 {GO:0004576=ISS, GO:0043066=IEA, GO:0007584=IEA, GO:0042493=IEA, GO:0001824=IEA, GO:0006915=IEA, GO:0004579=IC, GO:0005789=TAS, GO:0006486=ISS, GO:0016021=IEA, GO:0008250=TAS, GO:0044267=TAS, GO:0018279=TAS, GO:0043687=TAS} apoptotic process, blastocyst development, cellular protein metabolic process, negative regulation of apoptotic process, post-translational protein modification, protein N-linked glycosylation via asparagine, protein glycosylation, response to drug, response to nutrient endoplasmic reticulum membrane, integral to membrane, oligosaccharyltransferase complex dolichyl-diphosphooligosaccharide-protein glycotransferase activity, oligosaccharyl transferase activity Human DAG1 IntAct UniProtKB {GO:0051898=PMID:19587235, GO:0005515=PMID:19109891, GO:0034453=PMID:18341635, GO:0005886=PMID:18764929, GO:0022011=GO_REF:0000019, GO:0030175=PMID:18341635, GO:0006607=PMID:20512930, GO:0005615=PMID:18201566, GO:0043409=PMID:19587235, GO:0005737=PMID:18764929, GO:0016010=PMID:17993586, GO:0015631=PMID:18341635, GO:0016011=GO_REF:0000019, GO:0045211=GO_REF:0000039, GO:0021682=GO_REF:0000019, GO:0006509=PMID:19946898, GO:0008307=PMID:18691338, GO:0005856=GO_REF:0000039, GO:0042169=PMID:11724572, GO:0007016=PMID:18341635, GO:0030336=PMID:19587235, GO:0002011=GO_REF:0000019, GO:0005509=GO_REF:0000002, GO:0003779=PMID:18341635, GO:0030027=PMID:18341635, GO:0005604=PMID:19348877, GO:0042383=GO_REF:0000039, GO:0060441=GO_REF:0000019, GO:0033268=GO_REF:0000019, GO:0051393=PMID:18341635, GO:0019048=PMID:16254364, GO:0043237=GO_REF:0000024, GO:0017166=PMID:18341635, GO:0009279=GO_REF:0000019, GO:0045121=GO_REF:0000019, GO:0005654=PMID:18764929, GO:0016021=PMID:17628813, GO:0005925=PMID:18341635, GO:0070938=PMID:18341635, GO:0060445=GO_REF:0000019} Q14118 Dystroglycan protein 20130415 {GO:0051898=IMP, GO:0005515=IPI, GO:0034453=IMP, GO:0005886=IDA, GO:0022011=IEA, GO:0030175=IDA, GO:0006607=IDA, GO:0005615=IDA, GO:0043409=IMP, GO:0005737=IDA, GO:0016010=IDA, GO:0015631=IDA, GO:0016011=IEA, GO:0045211=IEA, GO:0021682=IEA, GO:0006509=IDA, GO:0008307=IMP, GO:0005856=IEA, GO:0042169=IDA, GO:0007016=IMP, GO:0030336=IMP, GO:0002011=IEA, GO:0005509=IEA, GO:0003779=IDA, GO:0030027=IDA, GO:0005604=IDA, GO:0042383=IEA, GO:0060441=IEA, GO:0033268=IEA, GO:0051393=IDA, GO:0019048=IDA, GO:0043237=ISS, GO:0017166=IPI, GO:0009279=IEA, GO:0045121=IEA, GO:0005654=IDA, GO:0016021=IDA, GO:0005925=IDA, GO:0070938=IDA, GO:0060445=IEA} NLS-bearing substrate import into nucleus, branching involved in salivary gland morphogenesis, cytoskeletal anchoring at plasma membrane, epithelial tube branching involved in lung morphogenesis, membrane protein ectodomain proteolysis, microtubule anchoring, morphogenesis of an epithelial sheet, myelination in peripheral nervous system, negative regulation of MAPK cascade, negative regulation of cell migration, negative regulation of protein kinase B signaling cascade, nerve maturation, virus-host interaction basement membrane, cell outer membrane, contractile ring, cytoplasm, cytoskeleton, dystroglycan complex, dystrophin-associated glycoprotein complex, extracellular space, filopodium, focal adhesion, integral to membrane, lamellipodium, membrane raft, node of Ranvier, nucleoplasm, plasma membrane, postsynaptic membrane, sarcolemma SH2 domain binding, actin binding, alpha-actinin binding, calcium ion binding, laminin-1 binding, protein binding, structural constituent of muscle, tubulin binding, vinculin binding Human UniProtKB:Q3T1J5 DAGLB Reactome UniProtKB {GO:0016042=GO_REF:0000037, GO:0006629=GO_REF:0000002, GO:0004806=GO_REF:0000002, GO:0005886=Reactome:REACT_19135, GO:0007596=Reactome:REACT_604, GO:0030168=Reactome:REACT_798, GO:0016021=GO_REF:0000037, GO:0046872=GO_REF:0000037} Q8NCG7 Sn1-specific diacylglycerol lipase beta protein 20130301 {GO:0016042=IEA, GO:0006629=IEA, GO:0004806=IEA, GO:0005886=TAS, GO:0007596=TAS, GO:0030168=TAS, GO:0016021=IEA, GO:0046872=IEA} blood coagulation, lipid catabolic process, lipid metabolic process, platelet activation integral to membrane, plasma membrane metal ion binding, triglyceride lipase activity Human DAK Reactome UniProtKB {GO:0050354=GO_REF:0000003, GO:0004371=GO_REF:0000003, GO:0045087=Reactome:REACT_6802, GO:0005524=GO_REF:0000037, GO:0006071=GO_REF:0000002, GO:0046872=GO_REF:0000037, GO:0005829=Reactome:REACT_25160, GO:0034012=GO_REF:0000003} Q3LXA3 Bifunctional ATP-dependent dihydroxyacetone kinase/FAD-AMP lyase (cyclizing) protein 20100802 {GO:0050354=IEA, GO:0004371=IEA, GO:0045087=TAS, GO:0005524=IEA, GO:0006071=IEA, GO:0046872=IEA, GO:0005829=TAS, GO:0034012=IEA} glycerol metabolic process, innate immune response cytosol ATP binding, FAD-AMP lyase (cyclizing) activity, glycerone kinase activity, metal ion binding, triokinase activity Human DALRD3 InterPro UniProtKB {GO:0006420=GO_REF:0000002, GO:0004814=GO_REF:0000002, GO:0005524=GO_REF:0000002} Q5D0E6 DALR anticodon-binding domain-containing protein 3 protein 20130413 {GO:0006420=IEA, GO:0004814=IEA, GO:0005524=IEA} arginyl-tRNA aminoacylation ATP binding, arginine-tRNA ligase activity Human InterPro:IPR008909 DAND5 BHF-UCL UniProtKB {GO:1900108=GO_REF:0000024, GO:0030514=GO_REF:0000024, GO:0016015=GO_REF:0000024, GO:0003140=GO_REF:0000024, GO:0003283=GO_REF:0000024, GO:0005576=PMID:15466485, GO:0003281=GO_REF:0000024, GO:0038101=GO_REF:0000024, GO:0061371=GO_REF:0000024, GO:0030512=GO_REF:0000024} Q8N907 DAN domain family member 5 protein 20120322 {GO:1900108=ISS, GO:0030514=ISS, GO:0016015=ISS, GO:0003140=ISS, GO:0003283=ISS, GO:0005576=NAS, GO:0003281=ISS, GO:0038101=ISS, GO:0061371=ISS, GO:0030512=ISS} atrial septum development, determination of heart left/right asymmetry, determination of left/right asymmetry in lateral mesoderm, negative regulation of BMP signaling pathway, negative regulation of nodal signaling pathway, negative regulation of transforming growth factor beta receptor signaling pathway, sequestering of nodal from receptor via nodal binding, ventricular septum development extracellular region morphogen activity Human UniProtKB:Q76LW6 DAO Reactome UniProtKB {GO:0005515=PMID:21679769, GO:0070178=PMID:21679769, GO:0048037=PMID:20603179, GO:0005782=Reactome:REACT_17049, GO:0005102=PMID:20178365, GO:0036088=PMID:18544534, GO:0005741=PMID:21679769, GO:0044281=Reactome:REACT_111217, GO:0005829=PMID:21679769, GO:0042416=PMID:17303072, GO:0034641=Reactome:REACT_13, GO:0071949=PMID:19309736, GO:0016641=GO_REF:0000002, GO:0046983=PMID:19309736, GO:0006562=PMID:16616139, GO:0046487=Reactome:REACT_16925, GO:0003884=Reactome:REACT_17049, GO:0055130=PMID:20603179, GO:0005778=PMID:21679769, GO:0006551=GO_REF:0000019, GO:0005777=PMID:18544534} P14920 D-amino-acid oxidase protein 20130213 {GO:0005515=IPI, GO:0070178=IDA, GO:0048037=IDA, GO:0005782=TAS, GO:0005102=IPI, GO:0036088=IDA, GO:0005741=IDA, GO:0044281=TAS, GO:0005829=IDA, GO:0042416=IDA, GO:0034641=TAS, GO:0071949=IDA, GO:0016641=IEA, GO:0046983=IDA, GO:0006562=IDA, GO:0046487=TAS, GO:0003884=TAS, GO:0055130=IDA, GO:0005778=IDA, GO:0006551=IEA, GO:0005777=IDA} D-alanine catabolic process, D-serine catabolic process, D-serine metabolic process, cellular nitrogen compound metabolic process, dopamine biosynthetic process, glyoxylate metabolic process, leucine metabolic process, proline catabolic process, small molecule metabolic process cytosol, mitochondrial outer membrane, peroxisomal matrix, peroxisomal membrane, peroxisome D-amino-acid oxidase activity, FAD binding, cofactor binding, oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor, protein binding, protein dimerization activity, receptor binding Human DAOA UniProtKB UniProtKB {GO:0005739=PMID:21679769, GO:0048471=PMID:21679769, GO:0005794=PMID:12364586, GO:0019899=PMID:21679769} P59103 D-amino acid oxidase activator protein 20120530 {GO:0005739=IDA, GO:0048471=IDA, GO:0005794=IDA, GO:0019899=IPI} Golgi apparatus, mitochondrion, perinuclear region of cytoplasm enzyme binding Human UniProtKB:P14920 DAP MGI UniProtKB {GO:0070513=PMID:1087798, GO:0006919=PMID:1087798, GO:0010507=PMID:20537536, GO:0006914=GO_REF:0000037, GO:0006915=PMID:7828849, GO:0032088=PMID:1087798, GO:0045892=PMID:1087798, GO:0097190=PMID:1087798, GO:0034198=PMID:20537536} P51397 Death-associated protein 1 protein 20120105 {GO:0070513=IPI, GO:0006919=IMP, GO:0010507=IMP, GO:0006914=IEA, GO:0006915=IGI, GO:0032088=IMP, GO:0045892=IMP, GO:0097190=IMP, GO:0034198=IDA} activation of cysteine-type endopeptidase activity involved in apoptotic process, apoptotic process, apoptotic signaling pathway, autophagy, cellular response to amino acid starvation, negative regulation of NF-kappaB transcription factor activity, negative regulation of autophagy, negative regulation of transcription, DNA-dependent death domain binding Human UniProtKB:P01579 DAP3 HPA UniProtKB {GO:0005739=GO_REF:0000052, GO:0005515=PMID:19103604, GO:0008637=GO_REF:0000019, GO:0005730=GO_REF:0000052, GO:0015935=GO_REF:0000002, GO:0005761=GO_REF:0000002, GO:0005634=GO_REF:0000052, GO:0097190=PMID:7499268} P51398 28S ribosomal protein S29, mitochondrial protein 20101115 {GO:0005739=IDA, GO:0005515=IPI, GO:0008637=IEA, GO:0005730=IDA, GO:0015935=IEA, GO:0005761=IEA, GO:0005634=IDA, GO:0097190=TAS} apoptotic mitochondrial changes, apoptotic signaling pathway mitochondrial ribosome, mitochondrion, nucleolus, nucleus, small ribosomal subunit protein binding Human DAPK1 InterPro UniProtKB {GO:0017148=PMID:18995835, GO:0005515=PMID:19712061, GO:0005516=PMID:10629061, GO:0043066=GO_REF:0000019, GO:0006915=Reactome:REACT_578, GO:2000310=GO_REF:0000024, GO:0042981=Reactome:REACT_13648, GO:0006917=PMID:10629061, GO:0015629=PMID:10629061, GO:0005524=GO_REF:0000002, GO:0097190=PMID:7828849, GO:0007243=PMID:10629061, GO:0042802=PMID:19712061, GO:0007165=GO_REF:0000002, GO:0005737=GO_REF:0000039, GO:0004672=PMID:7828849, GO:0046777=PMID:16756490, GO:0071346=PMID:18995835, GO:0004674=GO_REF:0000002, GO:0010506=PMID:16756490, GO:0006468=PMID:16756490} Q5T8F1 Death-associated protein kinase 1 protein 20130413 {GO:0017148=IDA, GO:0005515=IPI, GO:0005516=IDA, GO:0043066=IEA, GO:0006915=TAS, GO:2000310=ISS, GO:0042981=TAS, GO:0006917=IMP, GO:0015629=IDA, GO:0005524=IEA, GO:0097190=IMP, GO:0007243=IDA, GO:0042802=IPI, GO:0007165=IEA, GO:0005737=IEA, GO:0004672=IDA, GO:0046777=TAS, GO:0071346=IDA, GO:0004674=IEA, GO:0010506=TAS, GO:0006468=TAS} apoptotic process, apoptotic signaling pathway, cellular response to interferon-gamma, induction of apoptosis, intracellular protein kinase cascade, negative regulation of apoptotic process, negative regulation of translation, protein autophosphorylation, protein phosphorylation, regulation of N-methyl-D-aspartate selective glutamate receptor activity, regulation of apoptotic process, regulation of autophagy, signal transduction actin cytoskeleton, cytoplasm ATP binding, calmodulin binding, identical protein binding, protein binding, protein kinase activity, protein serine/threonine kinase activity Human InterPro:IPR000488 DAPK2 IntAct UniProtKB {GO:0005516=PMID:10376525, GO:0034423=GO_REF:0000039, GO:0043276=PMID:18957423, GO:0042981=PMID:16756490, GO:0031410=GO_REF:0000037, GO:0006917=PMID:10376525, GO:0005524=PMID:10376525, GO:0007243=PMID:10376525, GO:0042802=PMID:11230133, GO:0005737=PMID:10376525, GO:0004672=GO_REF:0000002, GO:0046777=PMID:16756490, GO:0004674=PMID:16756490, GO:0010506=PMID:16756490, GO:0006468=PMID:10376525, GO:0004683=PMID:10629061} Q9UIK4 Death-associated protein kinase 2 protein 20130415 {GO:0005516=IDA, GO:0034423=IEA, GO:0043276=IMP, GO:0042981=TAS, GO:0031410=IEA, GO:0006917=IMP, GO:0005524=IDA, GO:0007243=IDA, GO:0042802=IPI, GO:0005737=IDA, GO:0004672=IEA, GO:0046777=TAS, GO:0004674=TAS, GO:0010506=TAS, GO:0006468=IDA, GO:0004683=TAS} anoikis, induction of apoptosis, intracellular protein kinase cascade, protein autophosphorylation, protein phosphorylation, regulation of apoptotic process, regulation of autophagy autophagic vacuole lumen, cytoplasm, cytoplasmic vesicle ATP binding, calmodulin binding, calmodulin-dependent protein kinase activity, identical protein binding, protein kinase activity, protein serine/threonine kinase activity Human UniProtKB:Q9UIK4 DAPK3 UniProtKB UniProtKB {GO:0017148=PMID:18995835, GO:0090263=PMID:21454679, GO:2000145=DOI:10.1002/sita.200600112, GO:0005634=GO_REF:0000024, GO:0006940=DOI:10.1002/sita.200600112, GO:0007243=PMID:10356987, GO:0042803=PMID:18239682, GO:0043522=PMID:10580117, GO:2000249=DOI:10.1002/sita.200600112, GO:0000910=DOI:10.1002/sita.200600112, GO:0005737=GO_REF:0000039, GO:0046777=PMID:16756490, GO:0030182=GO_REF:0000019, GO:2001241=GO_REF:0000019, GO:0006355=DOI:10.1002/sita.200600112, GO:0007088=DOI:10.1002/sita.200600112, GO:0005815=GO_REF:0000039, GO:0006915=GO_REF:0000037, GO:0042981=PMID:16756490, GO:0006917=PMID:10580117, GO:0005524=PMID:10356987, GO:0006351=GO_REF:0000037, GO:0004672=GO_REF:0000002, GO:0071346=PMID:18995835, GO:0004674=PMID:16756490, GO:0016605=GO_REF:0000039, GO:0010506=PMID:16756490, GO:0006468=PMID:10356987, GO:0000775=GO_REF:0000039, GO:0016568=GO_REF:0000037} O43293 Death-associated protein kinase 3 protein 20121203 {GO:0017148=IDA, GO:0090263=IMP, GO:2000145=TAS, GO:0005634=ISS, GO:0006940=TAS, GO:0007243=IDA, GO:0042803=IDA, GO:0043522=IPI, GO:2000249=TAS, GO:0000910=TAS, GO:0005737=IEA, GO:0046777=TAS, GO:0030182=IEA, GO:2001241=IEA, GO:0006355=TAS, GO:0007088=TAS, GO:0005815=IEA, GO:0006915=IEA, GO:0042981=TAS, GO:0006917=IDA, GO:0005524=IDA, GO:0006351=IEA, GO:0004672=IEA, GO:0071346=IDA, GO:0004674=TAS, GO:0016605=IEA, GO:0010506=TAS, GO:0006468=IDA, GO:0000775=IEA, GO:0016568=IEA} apoptotic process, cellular response to interferon-gamma, chromatin modification, cytokinesis, induction of apoptosis, intracellular protein kinase cascade, negative regulation of translation, neuron differentiation, positive regulation of canonical Wnt receptor signaling pathway, positive regulation of extrinsic apoptotic signaling pathway in absence of ligand, protein autophosphorylation, protein phosphorylation, regulation of actin cytoskeleton reorganization, regulation of apoptotic process, regulation of autophagy, regulation of cell motility, regulation of mitosis, regulation of smooth muscle contraction, regulation of transcription, DNA-dependent, transcription, DNA-dependent PML body, chromosome, centromeric region, cytoplasm, microtubule organizing center, nucleus ATP binding, leucine zipper domain binding, protein homodimerization activity, protein kinase activity, protein serine/threonine kinase activity Human DAPP1 GOC UniProtKB {GO:0007165=PMID:10432293, GO:0006470=PMID:10432293, GO:0005543=PMID:10432293, GO:0005886=Reactome:REACT_118781, GO:0043325=PMID:17823121, GO:0005547=PMID:11001876, GO:0035335=GO_REF:0000029, GO:0004725=GO_REF:0000029, GO:0005829=Reactome:REACT_118566} Q9UN19 Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3-phosphoinositide protein 20130413 {GO:0007165=TAS, GO:0006470=NAS, GO:0005543=NAS, GO:0005886=TAS, GO:0043325=IDA, GO:0005547=IDA, GO:0035335=NAS, GO:0004725=NAS, GO:0005829=TAS} peptidyl-tyrosine dephosphorylation, protein dephosphorylation, signal transduction cytosol, plasma membrane phosphatidylinositol-3,4,5-trisphosphate binding, phosphatidylinositol-3,4-bisphosphate binding, phospholipid binding, protein tyrosine phosphatase activity Human DARC ENSEMBL UniProtKB {GO:0070098=GO_REF:0000029, GO:0006954=GO_REF:0000019, GO:0005886=Reactome:REACT_14786, GO:0004950=GO_REF:0000029, GO:0032642=GO_REF:0000019, GO:0004872=PMID:7689250, GO:0006952=PMID:10570183, GO:0016021=GO_REF:0000002, GO:0019957=PMID:7517217, GO:0019956=GO_REF:0000002, GO:0004888=PMID:9058825} Q5JY94 Duffy antigen/chemokine receptor protein 20130413 {GO:0070098=NAS, GO:0006954=IEA, GO:0005886=TAS, GO:0004950=NAS, GO:0032642=IEA, GO:0004872=TAS, GO:0006952=NAS, GO:0016021=IEA, GO:0019957=IPI, GO:0019956=IEA, GO:0004888=TAS} chemokine-mediated signaling pathway, defense response, inflammatory response, regulation of chemokine production integral to membrane, plasma membrane C-C chemokine binding, chemokine binding, chemokine receptor activity, receptor activity, transmembrane signaling receptor activity Human Ensembl:ENSMUSP00000045134 DARS HPA UniProtKB {GO:0005515=PMID:19380743, GO:0010467=Reactome:REACT_71, GO:0006422=GO_REF:0000002, GO:0005737=GO_REF:0000052, GO:0006461=PMID:8449960, GO:0004046=PMID:8449960, GO:0004815=GO_REF:0000003, GO:0003676=GO_REF:0000002, GO:0006412=PMID:8449960, GO:0005524=GO_REF:0000037, GO:0006418=Reactome:REACT_15482, GO:0005829=Reactome:REACT_15516} P14868 Aspartate--tRNA ligase, cytoplasmic protein 20111111 {GO:0005515=IPI, GO:0010467=TAS, GO:0006422=IEA, GO:0005737=IDA, GO:0006461=TAS, GO:0004046=TAS, GO:0004815=IEA, GO:0003676=IEA, GO:0006412=TAS, GO:0005524=IEA, GO:0006418=TAS, GO:0005829=TAS} aspartyl-tRNA aminoacylation, gene expression, protein complex assembly, tRNA aminoacylation for protein translation, translation cytoplasm, cytosol ATP binding, aminoacylase activity, aspartate-tRNA ligase activity, nucleic acid binding, protein binding Human DARS2 UniProtKB UniProtKB {GO:0005515=PMID:15779907, GO:0010467=Reactome:REACT_71, GO:0000049=PMID:15779907, GO:0050560=PMID:17384640, GO:0005634=GO_REF:0000052, GO:0004815=Reactome:REACT_15437, GO:0070145=PMID:15779907, GO:0005524=GO_REF:0000002, GO:0004812=GO_REF:0000038, GO:0042803=PMID:15779907, GO:0006418=GO_REF:0000002, GO:0005739=PMID:15779907, GO:0005737=GO_REF:0000002, GO:0005759=Reactome:REACT_15437, GO:0043039=PMID:17384640} Q9H9M6 cDNA FLJ12651 fis, clone NT2RM4002062, moderately similar to ASPARTYL-TRNA SYNTHETASE (EC 6.1.1.12) protein 20130413 {GO:0005515=IPI, GO:0010467=TAS, GO:0000049=TAS, GO:0050560=IDA, GO:0005634=IDA, GO:0004815=TAS, GO:0070145=IC, GO:0005524=IEA, GO:0004812=IEA, GO:0042803=IPI, GO:0006418=IEA, GO:0005739=TAS, GO:0005737=IEA, GO:0005759=TAS, GO:0043039=IDA} gene expression, mitochondrial asparaginyl-tRNA aminoacylation, tRNA aminoacylation, tRNA aminoacylation for protein translation cytoplasm, mitochondrial matrix, mitochondrion, nucleus ATP binding, aminoacyl-tRNA ligase activity, aspartate-tRNA ligase activity, aspartate-tRNA(Asn) ligase activity, protein binding, protein homodimerization activity, tRNA binding Human UniProtKB-KW:KW-0030 DAXX BHF-UCL UniProtKB {GO:0005515=PMID:21988832, GO:0000792=GO_REF:0000019, GO:0008625=PMID:9215629, GO:0005634=PMID:15878163, GO:0050681=PMID:15572661, GO:0005829=GO_REF:0000024, GO:0002039=PMID:16845383, GO:0005737=PMID:15572661, GO:0031072=PMID:15572661, GO:0031396=PMID:18566590, GO:0031625=PMID:16845383, GO:0006355=PMID:15878163, GO:0000281=GO_REF:0000019, GO:0005730=GO_REF:0000039, GO:0006915=PMID:15572661, GO:0006917=GO_REF:0000024, GO:0007257=PMID:9215629, GO:0006351=GO_REF:0000037, GO:0047485=PMID:18566590, GO:0019048=GO_REF:0000037, GO:0016605=PMID:15247905, GO:0005057=PMID:9215629, GO:0019899=PMID:16845383, GO:0045892=PMID:15572661, GO:0030521=PMID:15572661, GO:0000775=GO_REF:0000039} Q9UER7 Death domain-associated protein 6 protein 20081024 {GO:0005515=IPI, GO:0000792=IEA, GO:0008625=TAS, GO:0005634=IDA, GO:0050681=IPI, GO:0005829=ISS, GO:0002039=IPI, GO:0005737=TAS, GO:0031072=TAS, GO:0031396=IDA, GO:0031625=IPI, GO:0006355=IDA, GO:0000281=IEA, GO:0005730=IEA, GO:0006915=TAS, GO:0006917=ISS, GO:0007257=TAS, GO:0006351=IEA, GO:0047485=IPI, GO:0019048=IEA, GO:0016605=TAS, GO:0005057=TAS, GO:0019899=IPI, GO:0045892=IDA, GO:0030521=IDA, GO:0000775=IEA} activation of JUN kinase activity, androgen receptor signaling pathway, apoptotic process, cytokinesis after mitosis, extrinsic apoptotic signaling pathway via death domain receptors, induction of apoptosis, negative regulation of transcription, DNA-dependent, regulation of protein ubiquitination, regulation of transcription, DNA-dependent, transcription, DNA-dependent, virus-host interaction PML body, chromosome, centromeric region, cytoplasm, cytosol, heterochromatin, nucleolus, nucleus androgen receptor binding, enzyme binding, heat shock protein binding, p53 binding, protein N-terminus binding, protein binding, receptor signaling protein activity, ubiquitin protein ligase binding Human DAZ1 IntAct UniProtKB {GO:0005515=PMID:12511597, GO:0005737=GO_REF:0000039, GO:0000166=GO_REF:0000002, GO:0003723=GO_REF:0000037, GO:0045948=PMID:16001084, GO:0008494=PMID:16001084, GO:0005634=GO_REF:0000039, GO:0007275=GO_REF:0000037, GO:0007283=GO_REF:0000037, GO:0003676=GO_REF:0000002, GO:0030154=GO_REF:0000037} Q9NQZ3 Deleted in azoospermia protein 1 protein 20130415 {GO:0005515=IPI, GO:0005737=IEA, GO:0000166=IEA, GO:0003723=IEA, GO:0045948=IDA, GO:0008494=IDA, GO:0005634=IEA, GO:0007275=IEA, GO:0007283=IEA, GO:0003676=IEA, GO:0030154=IEA} cell differentiation, multicellular organismal development, positive regulation of translational initiation, spermatogenesis cytoplasm, nucleus RNA binding, nucleic acid binding, nucleotide binding, protein binding, translation activator activity Human UniProtKB:Q8TB72 DAZ2 PINC UniProtKB {GO:0007338=PMID:8896558, GO:0005737=GO_REF:0000039, GO:0000166=GO_REF:0000002, GO:0003723=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0007275=GO_REF:0000037, GO:0007283=GO_REF:0000037, GO:0003676=GO_REF:0000002, GO:0030154=GO_REF:0000037} Q13117 Deleted in azoospermia protein 2 protein 20030904 {GO:0007338=TAS, GO:0005737=IEA, GO:0000166=IEA, GO:0003723=IEA, GO:0005634=IEA, GO:0007275=IEA, GO:0007283=IEA, GO:0003676=IEA, GO:0030154=IEA} cell differentiation, multicellular organismal development, single fertilization, spermatogenesis cytoplasm, nucleus RNA binding, nucleic acid binding, nucleotide binding Human DAZ3 UniProtKB UniProtKB {GO:0005737=GO_REF:0000039, GO:0000166=GO_REF:0000002, GO:0003723=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0007275=GO_REF:0000037, GO:0007283=GO_REF:0000037, GO:0003676=GO_REF:0000002, GO:0030154=GO_REF:0000037} Q9NR90 Deleted in azoospermia protein 3 protein 20130413 {GO:0005737=IEA, GO:0000166=IEA, GO:0003723=IEA, GO:0005634=IEA, GO:0007275=IEA, GO:0007283=IEA, GO:0003676=IEA, GO:0030154=IEA} cell differentiation, multicellular organismal development, spermatogenesis cytoplasm, nucleus RNA binding, nucleic acid binding, nucleotide binding Human UniProtKB-SubCell:SL-0086 DAZ4 UniProtKB UniProtKB {GO:0005737=GO_REF:0000039, GO:0000166=GO_REF:0000002, GO:0003723=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0007275=GO_REF:0000037, GO:0007283=GO_REF:0000037, GO:0003676=GO_REF:0000002, GO:0030154=GO_REF:0000037} Q86SG3 Deleted in azoospermia protein 4 protein 20130413 {GO:0005737=IEA, GO:0000166=IEA, GO:0003723=IEA, GO:0005634=IEA, GO:0007275=IEA, GO:0007283=IEA, GO:0003676=IEA, GO:0030154=IEA} cell differentiation, multicellular organismal development, spermatogenesis cytoplasm, nucleus RNA binding, nucleic acid binding, nucleotide binding Human UniProtKB-SubCell:SL-0086 DAZAP1 HPA UniProtKB {GO:0005737=GO_REF:0000052, GO:0000166=GO_REF:0000002, GO:0003723=GO_REF:0000037, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0007275=GO_REF:0000037, GO:0007283=GO_REF:0000037, GO:0003676=GO_REF:0000002, GO:0030154=GO_REF:0000037} Q96EP5 DAZ-associated protein 1 protein 20080818 {GO:0005737=IDA, GO:0000166=IEA, GO:0003723=IEA, GO:0005730=IDA, GO:0005634=IDA, GO:0007275=IEA, GO:0007283=IEA, GO:0003676=IEA, GO:0030154=IEA} cell differentiation, multicellular organismal development, spermatogenesis cytoplasm, nucleolus, nucleus RNA binding, nucleic acid binding, nucleotide binding Human DAZAP2 IntAct UniProtKB {GO:0005515=PMID:19060904, GO:0005737=GO_REF:0000039, GO:0050699=PMID:11342538, GO:0005634=GO_REF:0000039} Q15038 DAZ-associated protein 2 protein 20130415 {GO:0005515=IPI, GO:0005737=IEA, GO:0050699=IPI, GO:0005634=IEA} cytoplasm, nucleus WW domain binding, protein binding Human UniProtKB:Q9UNA4 DAZL PINC UniProtKB {GO:0005515=PMID:16001084, GO:0005737=GO_REF:0000039, GO:0000166=GO_REF:0000002, GO:0003723=GO_REF:0000037, GO:0045948=PMID:16001084, GO:0008494=PMID:16001084, GO:0005634=GO_REF:0000039, GO:0007275=GO_REF:0000037, GO:0007283=GO_REF:0000037, GO:0003676=GO_REF:0000002, GO:0007281=PMID:9288969} Q92904 Deleted in azoospermia-like protein 20050308 {GO:0005515=IPI, GO:0005737=IEA, GO:0000166=IEA, GO:0003723=IEA, GO:0045948=IDA, GO:0008494=IDA, GO:0005634=IEA, GO:0007275=IEA, GO:0007283=IEA, GO:0003676=IEA, GO:0007281=TAS} germ cell development, multicellular organismal development, positive regulation of translational initiation, spermatogenesis cytoplasm, nucleus RNA binding, nucleic acid binding, nucleotide binding, protein binding, translation activator activity Human DBC1 HPA UniProtKB {GO:0005515=PMID:12442002, GO:0008219=PMID:14712213, GO:0005737=PMID:11420708, GO:0015630=GO_REF:0000052, GO:0007050=GO_REF:0000037, GO:0045786=PMID:11420708} O60477 Deleted in bladder cancer protein 1 protein 20110516 {GO:0005515=IPI, GO:0008219=IDA, GO:0005737=IDA, GO:0015630=IDA, GO:0007050=IEA, GO:0045786=IDA} cell cycle arrest, cell death, negative regulation of cell cycle cytoplasm, microtubule cytoskeleton protein binding Human DBF4 GOC UniProtKB {GO:0006260=Reactome:REACT_6769, GO:0000082=Reactome:REACT_1783, GO:0000075=Reactome:REACT_1538, GO:0005654=Reactome:REACT_6750, GO:0008270=GO_REF:0000002, GO:0043085=PMID:10373557, GO:0000278=Reactome:REACT_152, GO:0008047=PMID:10373557, GO:0003676=GO_REF:0000002} Q9UBU7 Protein DBF4 homolog A protein 20130413 {GO:0006260=TAS, GO:0000082=TAS, GO:0000075=TAS, GO:0005654=TAS, GO:0008270=IEA, GO:0043085=TAS, GO:0000278=TAS, GO:0008047=TAS, GO:0003676=IEA} DNA replication, G1/S transition of mitotic cell cycle, cell cycle checkpoint, mitotic cell cycle, positive regulation of catalytic activity nucleoplasm enzyme activator activity, nucleic acid binding, zinc ion binding Human DBF4B HPA UniProtKB {GO:0007049=GO_REF:0000037, GO:0016235=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0043231=GO_REF:0000052} Q8NFT6 Protein DBF4 homolog B protein 20120912 {GO:0007049=IEA, GO:0016235=IDA, GO:0005634=IDA, GO:0008270=IEA, GO:0003676=IEA, GO:0043231=IDA} cell cycle aggresome, intracellular membrane-bounded organelle, nucleus nucleic acid binding, zinc ion binding Human DBH InterPro UniProtKB {GO:0007268=PMID:2880016, GO:0044281=Reactome:REACT_111217, GO:0003824=PMID:3443096, GO:0001816=GO_REF:0000019, GO:0050900=GO_REF:0000019, GO:0034641=Reactome:REACT_13, GO:0004500=GO_REF:0000002, GO:0042596=GO_REF:0000019, GO:0005737=PMID:3443096, GO:0045907=GO_REF:0000019, GO:0042127=GO_REF:0000019, GO:0002443=GO_REF:0000019, GO:0007626=GO_REF:0000019, GO:0007613=GO_REF:0000019, GO:0030658=GO_REF:0000039, GO:0034466=GO_REF:0000039, GO:0042711=GO_REF:0000019, GO:0031418=GO_REF:0000037, GO:0005507=GO_REF:0000002, GO:0005576=PMID:14718574, GO:0042981=GO_REF:0000019, GO:0042593=GO_REF:0000019, GO:0001975=GO_REF:0000019, GO:0016020=PMID:3443096, GO:0042584=GO_REF:0000039, GO:0006584=GO_REF:0000002, GO:0001974=GO_REF:0000019, GO:0048149=GO_REF:0000019, GO:0042583=GO_REF:0000029, GO:0008542=GO_REF:0000019, GO:0042421=GO_REF:0000041, GO:0042420=GO_REF:0000019, GO:0048265=GO_REF:0000019, GO:0016021=GO_REF:0000037, GO:0042423=Reactome:REACT_15551, GO:0034774=Reactome:REACT_15372, GO:0042309=GO_REF:0000019} Q5T382 Dopamine beta-hydroxylase protein 20130413 {GO:0007268=TAS, GO:0044281=TAS, GO:0003824=TAS, GO:0001816=IEA, GO:0050900=IEA, GO:0034641=TAS, GO:0004500=IEA, GO:0042596=IEA, GO:0005737=TAS, GO:0045907=IEA, GO:0042127=IEA, GO:0002443=IEA, GO:0007626=IEA, GO:0007613=IEA, GO:0030658=IEA, GO:0034466=IEA, GO:0042711=IEA, GO:0031418=IEA, GO:0005507=IEA, GO:0005576=NAS, GO:0042981=IEA, GO:0042593=IEA, GO:0001975=IEA, GO:0016020=TAS, GO:0042584=IEA, GO:0006584=IEA, GO:0001974=IEA, GO:0048149=IEA, GO:0042583=NAS, GO:0008542=IEA, GO:0042421=IEA, GO:0042420=IEA, GO:0048265=IEA, GO:0016021=IEA, GO:0042423=TAS, GO:0034774=TAS, GO:0042309=IEA} behavioral response to ethanol, blood vessel remodeling, catecholamine biosynthetic process, catecholamine metabolic process, cellular nitrogen compound metabolic process, cytokine production, dopamine catabolic process, fear response, glucose homeostasis, homoiothermy, leukocyte mediated immunity, leukocyte migration, locomotory behavior, maternal behavior, memory, norepinephrine biosynthetic process, positive regulation of vasoconstriction, regulation of apoptotic process, regulation of cell proliferation, response to amphetamine, response to pain, small molecule metabolic process, synaptic transmission, visual learning chromaffin granule, chromaffin granule lumen, chromaffin granule membrane, cytoplasm, extracellular region, integral to membrane, membrane, secretory granule lumen, transport vesicle membrane L-ascorbic acid binding, catalytic activity, copper ion binding, dopamine beta-monooxygenase activity Human InterPro:IPR000945 DBI PINC UniProtKB {GO:0005739=GO_REF:0000019, GO:0005794=GO_REF:0000039, GO:0005783=GO_REF:0000039, GO:0006810=GO_REF:0000037, GO:0006641=GO_REF:0000019, GO:0043588=GO_REF:0000019, GO:0030156=PMID:3020548, GO:0001942=GO_REF:0000019, GO:0000062=GO_REF:0000002, GO:0008289=GO_REF:0000037} P07108 Acyl-CoA-binding protein protein 20040116 {GO:0005739=IEA, GO:0005794=IEA, GO:0005783=IEA, GO:0006810=IEA, GO:0006641=IEA, GO:0043588=IEA, GO:0030156=TAS, GO:0001942=IEA, GO:0000062=IEA, GO:0008289=IEA} hair follicle development, skin development, transport, triglyceride metabolic process Golgi apparatus, endoplasmic reticulum, mitochondrion benzodiazepine receptor binding, fatty-acyl-CoA binding, lipid binding Human DBN1 UniProtKB UniProtKB {GO:0042641=PMID:12761245, GO:0005886=GO_REF:0000019, GO:0048699=GO_REF:0000019, GO:0003779=PMID:12761245, GO:0015629=GO_REF:0000024, GO:0030425=PMID:12009525, GO:0005622=GO_REF:0000002, GO:0061351=GO_REF:0000019, GO:0005737=PMID:12009525, GO:0048168=PMID:12009525, GO:0050773=PMID:12009525, GO:0005921=GO_REF:0000019, GO:0007015=GO_REF:0000024, GO:0010643=GO_REF:0000019, GO:0032507=GO_REF:0000019, GO:0005522=GO_REF:0000024, GO:0010644=GO_REF:0000019} Q16643 Drebrin protein 20041006 {GO:0042641=NAS, GO:0005886=IEA, GO:0048699=IEA, GO:0003779=NAS, GO:0015629=ISS, GO:0030425=NAS, GO:0005622=IEA, GO:0061351=IEA, GO:0005737=NAS, GO:0048168=NAS, GO:0050773=NAS, GO:0005921=IEA, GO:0007015=ISS, GO:0010643=IEA, GO:0032507=IEA, GO:0005522=ISS, GO:0010644=IEA} actin filament organization, cell communication by chemical coupling, cell communication by electrical coupling, generation of neurons, maintenance of protein location in cell, neural precursor cell proliferation, regulation of dendrite development, regulation of neuronal synaptic plasticity actin cytoskeleton, actomyosin, cytoplasm, dendrite, gap junction, intracellular, plasma membrane actin binding, profilin binding Human UniProtKB:Q07266 DBNDD2 UniProtKB UniProtKB {GO:0005515=PMID:16618118, GO:0005737=GO_REF:0000002, GO:0006469=PMID:16618118} Q9BQY9 Dysbindin domain-containing protein 2 protein 20100127 {GO:0005515=IPI, GO:0005737=IEA, GO:0006469=IDA} negative regulation of protein kinase activity cytoplasm protein binding Human DBNL IntAct UniProtKB {GO:0005515=PMID:19060904, GO:0071800=GO_REF:0000024, GO:0030054=GO_REF:0000037, GO:0005886=GO_REF:0000039, GO:0002102=GO_REF:0000024, GO:0006921=Reactome:REACT_995, GO:0005829=Reactome:REACT_12025, GO:0005622=GO_REF:0000002, GO:0005737=GO_REF:0000024, GO:0051015=GO_REF:0000024, GO:0005938=GO_REF:0000024, GO:0019904=GO_REF:0000019, GO:0014069=GO_REF:0000019, GO:0006915=Reactome:REACT_578, GO:0003779=GO_REF:0000024, GO:0007257=PMID:10567356, GO:0008022=GO_REF:0000019, GO:0001726=GO_REF:0000024, GO:0007416=GO_REF:0000024, GO:0030027=GO_REF:0000024, GO:0006897=GO_REF:0000037, GO:0030665=GO_REF:0000039, GO:0016601=GO_REF:0000024, GO:0000139=GO_REF:0000039, GO:0048812=GO_REF:0000024, GO:0008047=PMID:10567356} Q9UJU6 Drebrin-like protein protein 20130415 {GO:0005515=IPI, GO:0071800=ISS, GO:0030054=IEA, GO:0005886=IEA, GO:0002102=ISS, GO:0006921=TAS, GO:0005829=TAS, GO:0005622=IEA, GO:0005737=ISS, GO:0051015=ISS, GO:0005938=ISS, GO:0019904=IEA, GO:0014069=IEA, GO:0006915=TAS, GO:0003779=ISS, GO:0007257=TAS, GO:0008022=IEA, GO:0001726=ISS, GO:0007416=ISS, GO:0030027=ISS, GO:0006897=IEA, GO:0030665=IEA, GO:0016601=ISS, GO:0000139=IEA, GO:0048812=ISS, GO:0008047=TAS} Rac protein signal transduction, activation of JUN kinase activity, apoptotic process, cellular component disassembly involved in execution phase of apoptosis, endocytosis, neuron projection morphogenesis, podosome assembly, synapse assembly Golgi membrane, cell cortex, cell junction, clathrin-coated vesicle membrane, cytoplasm, cytosol, intracellular, lamellipodium, plasma membrane, podosome, postsynaptic density, ruffle actin binding, actin filament binding, enzyme activator activity, protein C-terminus binding, protein binding, protein domain specific binding Human UniProtKB:Q9H788 DBP BHF-UCL UniProtKB {GO:0001889=GO_REF:0000019, GO:0043565=GO_REF:0000002, GO:0001077=PMID:20093779, GO:0000977=PMID:20093779, GO:0003700=GO_REF:0000002, GO:0006357=PMID:8786133, GO:0045944=PMID:20093779, GO:0005634=GO_REF:0000039, GO:0048511=GO_REF:0000037} Q10586 D site-binding protein protein 20111215 {GO:0001889=IEA, GO:0043565=IEA, GO:0001077=IDA, GO:0000977=IDA, GO:0003700=IEA, GO:0006357=TAS, GO:0045944=IDA, GO:0005634=IEA, GO:0048511=IEA} liver development, positive regulation of transcription from RNA polymerase II promoter, regulation of transcription from RNA polymerase II promoter, rhythmic process nucleus RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription, RNA polymerase II regulatory region sequence-specific DNA binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity Human DBR1 UniProtKB UniProtKB {GO:0008419=PMID:10982890, GO:0016787=GO_REF:0000002, GO:0000398=GO_REF:0000019, GO:0000375=PMID:10982890, GO:0016788=GO_REF:0000002, GO:0005634=PMID:10982890, GO:0046872=GO_REF:0000037} Q9UK59 Lariat debranching enzyme protein 20061214 {GO:0008419=IMP, GO:0016787=IEA, GO:0000398=IEA, GO:0000375=IMP, GO:0016788=IEA, GO:0005634=IDA, GO:0046872=IEA} RNA splicing, via transesterification reactions, mRNA splicing, via spliceosome nucleus RNA lariat debranching enzyme activity, hydrolase activity, hydrolase activity, acting on ester bonds, metal ion binding Human DBT HPA UniProtKB {GO:0005739=GO_REF:0000052, GO:0042645=PMID:18063578, GO:0034641=Reactome:REACT_13, GO:0005737=GO_REF:0000052, GO:0048037=GO_REF:0000002, GO:0005759=Reactome:REACT_1813, GO:0015630=GO_REF:0000052, GO:0043754=GO_REF:0000002, GO:0005947=PMID:1429740, GO:0009083=Reactome:REACT_197, GO:0044281=Reactome:REACT_111217, GO:0046949=GO_REF:0000002} Q5VVL7 Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex, mitochondrial protein 20100326 {GO:0005739=IDA, GO:0042645=IDA, GO:0034641=TAS, GO:0005737=IDA, GO:0048037=IEA, GO:0005759=TAS, GO:0015630=IDA, GO:0043754=IEA, GO:0005947=TAS, GO:0009083=TAS, GO:0044281=TAS, GO:0046949=IEA} branched-chain amino acid catabolic process, cellular nitrogen compound metabolic process, fatty-acyl-CoA biosynthetic process, small molecule metabolic process cytoplasm, microtubule cytoskeleton, mitochondrial alpha-ketoglutarate dehydrogenase complex, mitochondrial matrix, mitochondrial nucleoid, mitochondrion cofactor binding, dihydrolipoyllysine-residue (2-methylpropanoyl)transferase activity Human DCAF10 UniProtKB UniProtKB {GO:0016567=PMID:16949367, GO:0080008=PMID:16949367} Q5QP82 DDB1- and CUL4-associated factor 10 protein 20091211 {GO:0016567=IC, GO:0080008=IDA} protein ubiquitination Cul4-RING ubiquitin ligase complex Human DCAF11 IntAct UniProtKB {GO:0005515=PMID:22190034, GO:0016567=PMID:16949367, GO:0080008=PMID:16949367} Q8TEB1 DDB1- and CUL4-associated factor 11 protein 20130415 {GO:0005515=IPI, GO:0016567=IC, GO:0080008=IDA} protein ubiquitination Cul4-RING ubiquitin ligase complex protein binding Human UniProtKB:P12504 DCAF12 UniProtKB UniProtKB {GO:0005737=PMID:18957058, GO:0005813=PMID:18957058, GO:0016567=PMID:16949367, GO:0080008=PMID:16949367} Q5T6F0 DDB1- and CUL4-associated factor 12 protein 20091211 {GO:0005737=IDA, GO:0005813=IDA, GO:0016567=IC, GO:0080008=IDA} protein ubiquitination Cul4-RING ubiquitin ligase complex, centrosome, cytoplasm Human GO:0080008 DCAF12L2 null null {} null null null null {} null null null DCAF13 UniProtKB UniProtKB {GO:0016567=PMID:16949367, GO:0030529=GO_REF:0000037, GO:0006364=GO_REF:0000037, GO:0005730=GO_REF:0000039, GO:0080008=PMID:16949367} Q9NV06 DDB1- and CUL4-associated factor 13 protein 20091211 {GO:0016567=IC, GO:0030529=IEA, GO:0006364=IEA, GO:0005730=IEA, GO:0080008=IDA} protein ubiquitination, rRNA processing Cul4-RING ubiquitin ligase complex, nucleolus, ribonucleoprotein complex Human DCAF15 UniPathway UniProtKB {GO:0016567=GO_REF:0000041} Q66K64 DDB1- and CUL4-associated factor 15 protein 20130413 {GO:0016567=IEA} protein ubiquitination Human UniPathway:UPA00143 DCAF16 IntAct UniProtKB {GO:0005515=PMID:22190034, GO:0016567=PMID:16949367, GO:0080008=PMID:16949367} Q9NXF7 DDB1- and CUL4-associated factor 16 protein 20130415 {GO:0005515=IPI, GO:0016567=IC, GO:0080008=IDA} protein ubiquitination Cul4-RING ubiquitin ligase complex protein binding Human UniProtKB:P04608 DCAF17 UniProtKB UniProtKB {GO:0016567=PMID:16949367, GO:0005730=GO_REF:0000039, GO:0080008=PMID:16949367, GO:0016021=GO_REF:0000037} Q5H9S7 DDB1- and CUL4-associated factor 17 protein 20091211 {GO:0016567=IC, GO:0005730=IEA, GO:0080008=IDA, GO:0016021=IEA} protein ubiquitination Cul4-RING ubiquitin ligase complex, integral to membrane, nucleolus Human DCAF4 UniProtKB UniProtKB {GO:0016567=PMID:16949367, GO:0080008=PMID:16949367} Q8WV16 DDB1- and CUL4-associated factor 4 protein 20091211 {GO:0016567=IC, GO:0080008=IDA} protein ubiquitination Cul4-RING ubiquitin ligase complex Human GO:0080008 DCAF4L1 null null {} null null null null {} null null null DCAF5 UniProtKB UniProtKB {GO:0005739=GO_REF:0000019, GO:0016567=PMID:16949367, GO:0080008=PMID:16949367} Q96JK2 DDB1- and CUL4-associated factor 5 protein 20091211 {GO:0005739=IEA, GO:0016567=IC, GO:0080008=IDA} protein ubiquitination Cul4-RING ubiquitin ligase complex, mitochondrion Human GO:0080008 DCAF6 MGI UniProtKB {GO:0030374=PMID:15784617, GO:0016567=PMID:16949367, GO:0045944=PMID:15784617, GO:0005634=PMID:15784617, GO:0080008=PMID:16949367} Q58WW2 DDB1- and CUL4-associated factor 6 protein 20100304 {GO:0030374=IDA, GO:0016567=IC, GO:0045944=IGI, GO:0005634=IDA, GO:0080008=IDA} positive regulation of transcription from RNA polymerase II promoter, protein ubiquitination Cul4-RING ubiquitin ligase complex, nucleus ligand-dependent nuclear receptor transcription coactivator activity Human UniProtKB:P10275 DCAF7 HPA UniProtKB {GO:0005515=PMID:21328542, GO:0005737=GO_REF:0000052, GO:0016567=PMID:16949367, GO:0005730=GO_REF:0000052, GO:0007275=GO_REF:0000037, GO:0005634=GO_REF:0000052, GO:0080008=PMID:16949367} P61962 DDB1- and CUL4-associated factor 7 protein 20101115 {GO:0005515=IPI, GO:0005737=IDA, GO:0016567=IC, GO:0005730=IDA, GO:0007275=IEA, GO:0005634=IDA, GO:0080008=IDA} multicellular organismal development, protein ubiquitination Cul4-RING ubiquitin ligase complex, cytoplasm, nucleolus, nucleus protein binding Human DCAF8 IntAct UniProtKB {GO:0005515=PMID:22190034, GO:0016567=PMID:16949367, GO:0080008=PMID:16949367, GO:0005777=GO_REF:0000002} Q5TAQ9 DDB1- and CUL4-associated factor 8 protein 20130415 {GO:0005515=IPI, GO:0016567=IC, GO:0080008=IDA, GO:0005777=IEA} protein ubiquitination Cul4-RING ubiquitin ligase complex, peroxisome protein binding Human UniProtKB:P12520 DCAF8L2 null null {} null null null null {} null null null DCAKD ENSEMBL UniProtKB {GO:0005739=GO_REF:0000019, GO:0004140=GO_REF:0000002, GO:0015937=GO_REF:0000002, GO:0005524=GO_REF:0000037} Q8WVC6 Dephospho-CoA kinase domain-containing protein protein 20130413 {GO:0005739=IEA, GO:0004140=IEA, GO:0015937=IEA, GO:0005524=IEA} coenzyme A biosynthetic process mitochondrion ATP binding, dephospho-CoA kinase activity Human Ensembl:ENSMUSP00000021313 DCBLD1 UniProtKB UniProtKB {GO:0016021=GO_REF:0000037, GO:0007155=GO_REF:0000002} Q8N8Z6 Discoidin, CUB and LCCL domain-containing protein 1 protein 20130413 {GO:0016021=IEA, GO:0007155=IEA} cell adhesion integral to membrane Human UniProtKB-KW:KW-0812 DCBLD2 UniProtKB UniProtKB {GO:0030308=PMID:11447234, GO:0009986=PMID:11447234, GO:0005887=PMID:11447234, GO:0042060=PMID:11447234, GO:0007155=GO_REF:0000002, GO:0030522=PMID:11447234} Q96PD2 Discoidin, CUB and LCCL domain-containing protein 2 protein 20031216 {GO:0030308=IDA, GO:0009986=IDA, GO:0005887=IDA, GO:0042060=IDA, GO:0007155=IEA, GO:0030522=NAS} cell adhesion, intracellular receptor signaling pathway, negative regulation of cell growth, wound healing cell surface, integral to plasma membrane Human DCC BHF-UCL UniProtKB {GO:0005515=PMID:20434207, GO:0030424=GO_REF:0000019, GO:0005886=Reactome:REACT_22440, GO:0021965=GO_REF:0000019, GO:0007409=PMID:8861902, GO:0033563=GO_REF:0000019, GO:0048671=PMID:19616629, GO:0042802=GO_REF:0000019, GO:0005829=Reactome:REACT_22440, GO:0005042=GO_REF:0000019, GO:0007411=Reactome:REACT_18266, GO:0070374=GO_REF:0000019, GO:2000171=PMID:19616629, GO:0003713=GO_REF:0000019, GO:0032584=GO_REF:0000019, GO:0006915=Reactome:REACT_578, GO:0042981=Reactome:REACT_13648, GO:0006917=PMID:9796814, GO:0001975=GO_REF:0000019, GO:0010976=GO_REF:0000019, GO:0010977=PMID:19616629, GO:0045121=GO_REF:0000019, GO:0016021=GO_REF:0000037, GO:0001764=GO_REF:0000019, GO:0004888=PMID:8861902} P43146 Netrin receptor DCC protein 20110427 {GO:0005515=IPI, GO:0030424=IEA, GO:0005886=TAS, GO:0021965=IEA, GO:0007409=TAS, GO:0033563=IEA, GO:0048671=TAS, GO:0042802=IEA, GO:0005829=TAS, GO:0005042=IEA, GO:0007411=TAS, GO:0070374=IEA, GO:2000171=TAS, GO:0003713=IEA, GO:0032584=IEA, GO:0006915=TAS, GO:0042981=TAS, GO:0006917=TAS, GO:0001975=IEA, GO:0010976=IEA, GO:0010977=TAS, GO:0045121=IEA, GO:0016021=IEA, GO:0001764=IEA, GO:0004888=TAS} apoptotic process, axon guidance, axonogenesis, dorsal/ventral axon guidance, induction of apoptosis, negative regulation of collateral sprouting, negative regulation of dendrite development, negative regulation of neuron projection development, neuron migration, positive regulation of ERK1 and ERK2 cascade, positive regulation of neuron projection development, regulation of apoptotic process, response to amphetamine, spinal cord ventral commissure morphogenesis axon, cytosol, growth cone membrane, integral to membrane, membrane raft, plasma membrane identical protein binding, netrin receptor activity, protein binding, transcription coactivator activity, transmembrane signaling receptor activity Human DCD UniProtKB UniProtKB {GO:0050832=GO_REF:0000037, GO:0031640=GO_REF:0000037, GO:0006508=GO_REF:0000037, GO:0005576=PMID:9736629, GO:0008233=GO_REF:0000037, GO:0042742=GO_REF:0000037} P81605 Dermcidin protein 20010828 {GO:0050832=IEA, GO:0031640=IEA, GO:0006508=IEA, GO:0005576=IDA, GO:0008233=IEA, GO:0042742=IEA} defense response to bacterium, defense response to fungus, killing of cells of other organism, proteolysis extracellular region peptidase activity Human DCDC2 PINC UniProtKB {GO:0035556=GO_REF:0000002, GO:0048813=GO_REF:0000019, GO:0006968=PMID:10601354, GO:0001764=GO_REF:0000024} Q9UHG0 Doublecortin domain-containing protein 2 protein 20050308 {GO:0035556=IEA, GO:0048813=IEA, GO:0006968=TAS, GO:0001764=ISS} cellular defense response, dendrite morphogenesis, intracellular signal transduction, neuron migration Human DCHS1 UniProtKB UniProtKB {GO:0016339=PMID:9199196, GO:0016020=PMID:9199196, GO:0005886=GO_REF:0000039, GO:0005509=GO_REF:0000002, GO:0016021=GO_REF:0000037, GO:0007156=GO_REF:0000002} Q96JQ0 Protocadherin-16 protein 20021105 {GO:0016339=NAS, GO:0016020=NAS, GO:0005886=IEA, GO:0005509=IEA, GO:0016021=IEA, GO:0007156=IEA} calcium-dependent cell-cell adhesion, homophilic cell adhesion integral to membrane, membrane, plasma membrane calcium ion binding Human DCHS2 UniProtKB UniProtKB {GO:0005886=GO_REF:0000002, GO:0005509=GO_REF:0000002, GO:0016021=GO_REF:0000037, GO:0007156=GO_REF:0000002} Q6V1P9 Protocadherin-23 protein 20130413 {GO:0005886=IEA, GO:0005509=IEA, GO:0016021=IEA, GO:0007156=IEA} homophilic cell adhesion integral to membrane, plasma membrane calcium ion binding Human UniProtKB-KW:KW-0812 DCK GOC UniProtKB {GO:0055086=Reactome:REACT_1698, GO:0005634=GO_REF:0000039, GO:0044281=Reactome:REACT_111217, GO:0006220=PMID:12808445, GO:0043097=Reactome:REACT_655, GO:0019206=Reactome:REACT_1547, GO:0005524=GO_REF:0000037, GO:0009165=Reactome:REACT_1547, GO:0042803=PMID:12808445, GO:0005829=Reactome:REACT_1547, GO:0006139=GO_REF:0000002, GO:0006144=Reactome:REACT_522, GO:0008144=PMID:12808445, GO:0043101=Reactome:REACT_1923, GO:0016773=GO_REF:0000002, GO:0004137=PMID:12808445, GO:0006206=Reactome:REACT_957} P27707 Deoxycytidine kinase protein 20130413 {GO:0055086=TAS, GO:0005634=IEA, GO:0044281=TAS, GO:0006220=IDA, GO:0043097=TAS, GO:0019206=EXP, GO:0005524=IEA, GO:0009165=EXP, GO:0042803=IPI, GO:0005829=TAS, GO:0006139=IEA, GO:0006144=TAS, GO:0008144=IDA, GO:0043101=TAS, GO:0016773=IEA, GO:0004137=IDA, GO:0006206=TAS} nucleobase-containing compound metabolic process, nucleobase-containing small molecule metabolic process, nucleotide biosynthetic process, purine nucleobase metabolic process, purine-containing compound salvage, pyrimidine nucleobase metabolic process, pyrimidine nucleoside salvage, pyrimidine nucleotide metabolic process, small molecule metabolic process cytosol, nucleus ATP binding, deoxycytidine kinase activity, drug binding, nucleoside kinase activity, phosphotransferase activity, alcohol group as acceptor, protein homodimerization activity Human DCLK1 InterPro UniProtKB {GO:0021952=GO_REF:0000019, GO:0048675=GO_REF:0000019, GO:0007417=PMID:10051403, GO:0009615=PMID:16548883, GO:0005524=GO_REF:0000037, GO:0007399=PMID:10036192, GO:0035556=GO_REF:0000002, GO:0048813=GO_REF:0000019, GO:0004672=PMID:9747029, GO:0004674=GO_REF:0000037, GO:0005887=PMID:10036192, GO:0016197=PMID:14613930, GO:0006468=PMID:9747029, GO:0030900=GO_REF:0000019, GO:0005057=PMID:10036192, GO:0001764=GO_REF:0000019} Q5VZY9 Serine/threonine-protein kinase DCLK1 protein 20130413 {GO:0021952=IEA, GO:0048675=IEA, GO:0007417=TAS, GO:0009615=IEP, GO:0005524=IEA, GO:0007399=TAS, GO:0035556=IEA, GO:0048813=IEA, GO:0004672=TAS, GO:0004674=IEA, GO:0005887=TAS, GO:0016197=NAS, GO:0006468=TAS, GO:0030900=IEA, GO:0005057=TAS, GO:0001764=IEA} axon extension, central nervous system development, central nervous system projection neuron axonogenesis, dendrite morphogenesis, endosomal transport, forebrain development, intracellular signal transduction, nervous system development, neuron migration, protein phosphorylation, response to virus integral to plasma membrane ATP binding, protein kinase activity, protein serine/threonine kinase activity, receptor signaling protein activity Human InterPro:IPR003533 DCLK2 UniProtKB UniProtKB {GO:0035556=GO_REF:0000002, GO:0005737=GO_REF:0000037, GO:0004674=GO_REF:0000037, GO:0005856=GO_REF:0000039, GO:0005524=GO_REF:0000037} Q8N568 Serine/threonine-protein kinase DCLK2 protein 20130413 {GO:0035556=IEA, GO:0005737=IEA, GO:0004674=IEA, GO:0005856=IEA, GO:0005524=IEA} intracellular signal transduction cytoplasm, cytoskeleton ATP binding, protein serine/threonine kinase activity Human UniProtKB-SubCell:SL-0090 DCLK3 UniProtKB UniProtKB {GO:0005737=GO_REF:0000039, GO:0004674=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0005524=GO_REF:0000037} Q9C098 Serine/threonine-protein kinase DCLK3 protein 20130413 {GO:0005737=IEA, GO:0004674=IEA, GO:0005634=IEA, GO:0005524=IEA} cytoplasm, nucleus ATP binding, protein serine/threonine kinase activity Human UniProtKB-SubCell:SL-0086 DCLRE1A HPA UniProtKB {GO:0007067=GO_REF:0000037, GO:0016787=GO_REF:0000002, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0006289=GO_REF:0000019, GO:0051301=GO_REF:0000037} Q6PJP8 DNA cross-link repair 1A protein protein 20110516 {GO:0007067=IEA, GO:0016787=IEA, GO:0005730=IDA, GO:0005634=IDA, GO:0006289=IEA, GO:0051301=IEA} cell division, mitosis, nucleotide-excision repair nucleolus, nucleus hydrolase activity Human DCLRE1B IntAct UniProtKB {GO:0005515=PMID:16730175, GO:0000781=PMID:16730175, GO:0005813=PMID:19197158, GO:0005737=GO_REF:0000037, GO:0008409=PMID:16730175, GO:0006281=GO_REF:0000037, GO:0031860=GO_REF:0000024, GO:0000723=PMID:20655466, GO:0000075=PMID:19197158, GO:0005634=GO_REF:0000039, GO:0031627=GO_REF:0000024, GO:0031848=PMID:16730175} Q9H816 5' exonuclease Apollo protein 20130415 {GO:0005515=IPI, GO:0000781=IDA, GO:0005813=IDA, GO:0005737=IEA, GO:0008409=IDA, GO:0006281=IEA, GO:0031860=ISS, GO:0000723=IMP, GO:0000075=IMP, GO:0005634=IEA, GO:0031627=ISS, GO:0031848=IMP} DNA repair, cell cycle checkpoint, protection from non-homologous end joining at telomere, telomere maintenance, telomeric 3' overhang formation, telomeric loop formation centrosome, chromosome, telomeric region, cytoplasm, nucleus 5'-3' exonuclease activity, protein binding Human UniProtKB:Q15554 DCLRE1C MGI UniProtKB {GO:0008409=PMID:11955432, GO:0000723=GO_REF:0000019, GO:0010212=GO_REF:0000019, GO:0030183=GO_REF:0000019, GO:0000014=PMID:11955432, GO:0005634=GO_REF:0000039, GO:0006310=GO_REF:0000019, GO:0006302=GO_REF:0000019} Q96SD1 Protein artemis protein 20091019 {GO:0008409=IDA, GO:0000723=IEA, GO:0010212=IEA, GO:0030183=IEA, GO:0000014=IDA, GO:0005634=IEA, GO:0006310=IEA, GO:0006302=IEA} B cell differentiation, DNA recombination, double-strand break repair, response to ionizing radiation, telomere maintenance nucleus 5'-3' exonuclease activity, single-stranded DNA specific endodeoxyribonuclease activity Human DCN BHF-UCL UniProtKB {GO:0019800=GO_REF:0000019, GO:0005518=GO_REF:0000019, GO:0005589=GO_REF:0000019, GO:0005539=GO_REF:0000019, GO:0044281=Reactome:REACT_111217, GO:0030208=Reactome:REACT_120800, GO:0030207=Reactome:REACT_120888, GO:0030206=Reactome:REACT_120989, GO:0032496=GO_REF:0000019, GO:0009887=PMID:7961765, GO:0030204=Reactome:REACT_121206, GO:0030203=Reactome:REACT_121408, GO:0043202=Reactome:REACT_121272, GO:0001822=GO_REF:0000019, GO:0005796=Reactome:REACT_121341, GO:0005975=Reactome:REACT_474, GO:0007568=GO_REF:0000019, GO:0050840=GO_REF:0000019, GO:0005576=Reactome:REACT_121341, GO:0001890=GO_REF:0000019, GO:0009612=GO_REF:0000019, GO:0031012=PMID:22261194, GO:0047485=GO_REF:0000019, GO:0007519=GO_REF:0000019, GO:0042060=GO_REF:0000019} P07585 Decorin protein 20120228 {GO:0019800=IEA, GO:0005518=IEA, GO:0005589=IEA, GO:0005539=IEA, GO:0044281=TAS, GO:0030208=TAS, GO:0030207=TAS, GO:0030206=TAS, GO:0032496=IEA, GO:0009887=TAS, GO:0030204=TAS, GO:0030203=TAS, GO:0043202=TAS, GO:0001822=IEA, GO:0005796=TAS, GO:0005975=TAS, GO:0007568=IEA, GO:0050840=IEA, GO:0005576=TAS, GO:0001890=IEA, GO:0009612=IEA, GO:0031012=ISS, GO:0047485=IEA, GO:0007519=IEA, GO:0042060=IEA} aging, carbohydrate metabolic process, chondroitin sulfate biosynthetic process, chondroitin sulfate catabolic process, chondroitin sulfate metabolic process, dermatan sulfate biosynthetic process, glycosaminoglycan metabolic process, kidney development, organ morphogenesis, peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan, placenta development, response to lipopolysaccharide, response to mechanical stimulus, skeletal muscle tissue development, small molecule metabolic process, wound healing Golgi lumen, collagen type VI, extracellular matrix, extracellular region, lysosomal lumen collagen binding, extracellular matrix binding, glycosaminoglycan binding, protein N-terminus binding colocalizes_with Human UniProtKB:Q9XSD9 DCP1A IntAct UniProtKB {GO:0005515=PMID:16364915, GO:0010467=Reactome:REACT_71, GO:0016070=Reactome:REACT_21257, GO:0016787=GO_REF:0000037, GO:0000184=GO_REF:0000037, GO:0016071=Reactome:REACT_20605, GO:0000932=GO_REF:0000024, GO:0043928=Reactome:REACT_20518, GO:0005634=GO_REF:0000039, GO:0042802=PMID:16364915, GO:0005829=Reactome:REACT_25297, GO:0000288=Reactome:REACT_20639} Q9NPI6 mRNA-decapping enzyme 1A protein 20130415 {GO:0005515=IPI, GO:0010467=TAS, GO:0016070=TAS, GO:0016787=IEA, GO:0000184=IEA, GO:0016071=TAS, GO:0000932=ISS, GO:0043928=TAS, GO:0005634=IEA, GO:0042802=IPI, GO:0005829=TAS, GO:0000288=TAS} RNA metabolic process, exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay, gene expression, mRNA metabolic process, nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay, nuclear-transcribed mRNA catabolic process, nonsense-mediated decay cytoplasmic mRNA processing body, cytosol, nucleus hydrolase activity, identical protein binding, protein binding Human UniProtKB:Q9NPI6 DCP1B HPA UniProtKB {GO:0005515=PMID:16364915, GO:0010467=Reactome:REACT_71, GO:0005737=GO_REF:0000052, GO:0016070=Reactome:REACT_21257, GO:0016787=GO_REF:0000037, GO:0000184=GO_REF:0000037, GO:0016071=Reactome:REACT_20605, GO:0043928=Reactome:REACT_20518, GO:0005634=GO_REF:0000039, GO:0005829=Reactome:REACT_20560, GO:0000288=Reactome:REACT_20639, GO:0043231=GO_REF:0000052} Q8IZD4 mRNA-decapping enzyme 1B protein 20110516 {GO:0005515=IPI, GO:0010467=TAS, GO:0005737=IDA, GO:0016070=TAS, GO:0016787=IEA, GO:0000184=IEA, GO:0016071=TAS, GO:0043928=TAS, GO:0005634=IEA, GO:0005829=TAS, GO:0000288=TAS, GO:0043231=IDA} RNA metabolic process, exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay, gene expression, mRNA metabolic process, nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay, nuclear-transcribed mRNA catabolic process, nonsense-mediated decay cytoplasm, cytosol, intracellular membrane-bounded organelle, nucleus hydrolase activity, protein binding Human DCP2 IntAct UniProtKB {GO:0005515=PMID:16364915, GO:0010467=Reactome:REACT_71, GO:0016896=Reactome:REACT_20560, GO:0030145=GO_REF:0000002, GO:0016070=Reactome:REACT_21257, GO:0016071=Reactome:REACT_20605, GO:0003723=GO_REF:0000037, GO:0043928=Reactome:REACT_20518, GO:0005634=GO_REF:0000039, GO:0006402=PMID:21070968, GO:0050072=PMID:21070968, GO:0016442=PMID:20616046, GO:0005829=Reactome:REACT_25297, GO:0016787=GO_REF:0000038, GO:0000184=PMID:22890540, GO:0000932=PMID:20616046, GO:0071044=PMID:18172165, GO:0000288=Reactome:REACT_20639} Q8IU60 m7GpppN-mRNA hydrolase protein 20130415 {GO:0005515=IPI, GO:0010467=TAS, GO:0016896=TAS, GO:0030145=IEA, GO:0016070=TAS, GO:0016071=TAS, GO:0003723=IEA, GO:0043928=TAS, GO:0005634=IEA, GO:0006402=IDA, GO:0050072=IDA, GO:0016442=IDA, GO:0005829=TAS, GO:0016787=IEA, GO:0000184=IMP, GO:0000932=IDA, GO:0071044=IMP, GO:0000288=TAS} RNA metabolic process, exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay, gene expression, histone mRNA catabolic process, mRNA catabolic process, mRNA metabolic process, nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay, nuclear-transcribed mRNA catabolic process, nonsense-mediated decay RNA-induced silencing complex, cytoplasmic mRNA processing body, cytosol, nucleus RNA binding, exoribonuclease activity, producing 5'-phosphomonoesters, hydrolase activity, m7G(5')pppN diphosphatase activity, manganese ion binding, protein binding Human UniProtKB:Q9NPI6 DCPS HPA UniProtKB {GO:0005515=PMID:16140270, GO:0036245=PMID:16140270, GO:0010467=Reactome:REACT_71, GO:0016070=Reactome:REACT_21257, GO:0016071=Reactome:REACT_20605, GO:0045292=PMID:18426921, GO:0005730=GO_REF:0000052, GO:0043928=Reactome:REACT_20619, GO:0000290=GO_REF:0000002, GO:0005634=GO_REF:0000052, GO:0050072=PMID:18426921, GO:0005829=Reactome:REACT_20556, GO:0005739=GO_REF:0000052, GO:0043069=PMID:16140270, GO:0005737=PMID:18441014, GO:0000340=PMID:18426921, GO:0000288=Reactome:REACT_20639} Q96C86 m7GpppX diphosphatase protein 20110516 {GO:0005515=IPI, GO:0036245=IDA, GO:0010467=TAS, GO:0016070=TAS, GO:0016071=TAS, GO:0045292=IDA, GO:0005730=IDA, GO:0043928=TAS, GO:0000290=IEA, GO:0005634=IDA, GO:0050072=IDA, GO:0005829=TAS, GO:0005739=IDA, GO:0043069=IDA, GO:0005737=IDA, GO:0000340=IDA, GO:0000288=TAS} RNA metabolic process, cellular response to menadione, deadenylation-dependent decapping of nuclear-transcribed mRNA, exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay, gene expression, mRNA cis splicing, via spliceosome, mRNA metabolic process, negative regulation of programmed cell death, nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay cytoplasm, cytosol, mitochondrion, nucleolus, nucleus RNA 7-methylguanosine cap binding, m7G(5')pppN diphosphatase activity, protein binding Human DCST1 UniProtKB UniProtKB {GO:0008270=GO_REF:0000002, GO:0016021=GO_REF:0000037} Q5T197 DC-STAMP domain-containing protein 1 protein 20130413 {GO:0008270=IEA, GO:0016021=IEA} integral to membrane zinc ion binding Human UniProtKB-KW:KW-0812 DCST2 UniProtKB UniProtKB {GO:0016021=GO_REF:0000037} Q5T1A1 DC-STAMP domain-containing protein 2 protein 20130413 {GO:0016021=IEA} integral to membrane Human UniProtKB-KW:KW-0812 DCT PINC UniProtKB {GO:0033162=GO_REF:0000039, GO:0042470=GO_REF:0000024, GO:0021847=GO_REF:0000019, GO:0005507=PMID:8206391, GO:0002052=GO_REF:0000019, GO:0046872=GO_REF:0000038, GO:0005829=GO_REF:0000024, GO:0004167=GO_REF:0000024, GO:0008544=PMID:8206391, GO:0006583=GO_REF:0000024, GO:0016491=GO_REF:0000002, GO:0016021=GO_REF:0000037, GO:0048468=GO_REF:0000019, GO:0048066=GO_REF:0000019} P40126 L-dopachrome tautomerase protein 20030904 {GO:0033162=IEA, GO:0042470=ISS, GO:0021847=IEA, GO:0005507=TAS, GO:0002052=IEA, GO:0046872=IEA, GO:0005829=ISS, GO:0004167=ISS, GO:0008544=TAS, GO:0006583=ISS, GO:0016491=IEA, GO:0016021=IEA, GO:0048468=IEA, GO:0048066=IEA} cell development, developmental pigmentation, epidermis development, melanin biosynthetic process from tyrosine, positive regulation of neuroblast proliferation, ventricular zone neuroblast division cytosol, integral to membrane, melanosome, melanosome membrane copper ion binding, dopachrome isomerase activity, metal ion binding, oxidoreductase activity Human DCTD Reactome UniProtKB {GO:0046134=Reactome:REACT_21376, GO:0016787=GO_REF:0000002, GO:0016810=GO_REF:0000002, GO:0055086=Reactome:REACT_1698, GO:0008270=GO_REF:0000002, GO:0044281=Reactome:REACT_111217, GO:0006220=PMID:7685356, GO:0006206=Reactome:REACT_957, GO:0004132=Reactome:REACT_879, GO:0009165=GO_REF:0000037, GO:0005829=Reactome:REACT_879} P32321 Deoxycytidylate deaminase protein 20130213 {GO:0046134=TAS, GO:0016787=IEA, GO:0016810=IEA, GO:0055086=TAS, GO:0008270=IEA, GO:0044281=TAS, GO:0006220=TAS, GO:0006206=TAS, GO:0004132=EXP, GO:0009165=IEA, GO:0005829=TAS} nucleobase-containing small molecule metabolic process, nucleotide biosynthetic process, pyrimidine nucleobase metabolic process, pyrimidine nucleoside biosynthetic process, pyrimidine nucleotide metabolic process, small molecule metabolic process cytosol dCMP deaminase activity, hydrolase activity, hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, zinc ion binding Human DCTN1 IntAct UniProtKB {GO:0005515=PMID:18000879, GO:0008219=GO_REF:0000037, GO:0005813=PMID:21399614, GO:0005874=PMID:21525035, GO:0030968=Reactome:REACT_18356, GO:0005829=Reactome:REACT_120995, GO:0007399=PMID:17360970, GO:0019886=Reactome:REACT_121399, GO:0003774=GO_REF:0000037, GO:0000922=PMID:14718566, GO:0005737=PMID:1828535, GO:0007067=PMID:1828535, GO:0030286=GO_REF:0000037, GO:0000086=Reactome:REACT_2203, GO:0006810=GO_REF:0000037, GO:0000776=PMID:19468067, GO:0006987=Reactome:REACT_18368, GO:0000278=Reactome:REACT_152, GO:0044267=Reactome:REACT_17015, GO:0031252=GO_REF:0000019} Q14203 Dynactin subunit 1 protein 20130415 {GO:0005515=IPI, GO:0008219=IEA, GO:0005813=IDA, GO:0005874=IDA, GO:0030968=TAS, GO:0005829=TAS, GO:0007399=NAS, GO:0019886=TAS, GO:0003774=IEA, GO:0000922=IDA, GO:0005737=TAS, GO:0007067=NAS, GO:0030286=IEA, GO:0000086=TAS, GO:0006810=IEA, GO:0000776=IDA, GO:0006987=TAS, GO:0000278=TAS, GO:0044267=TAS, GO:0031252=IEA} G2/M transition of mitotic cell cycle, activation of signaling protein activity involved in unfolded protein response, antigen processing and presentation of exogenous peptide antigen via MHC class II, cell death, cellular protein metabolic process, endoplasmic reticulum unfolded protein response, mitosis, mitotic cell cycle, nervous system development, transport cell leading edge, centrosome, cytoplasm, cytosol, dynein complex, kinetochore, microtubule, spindle pole motor activity, protein binding Human UniProtKB:Q96RK4 DCTN2 HPA UniProtKB {GO:0005515=PMID:17043677, GO:0005813=GO_REF:0000052, GO:0008283=PMID:8647893, GO:0005874=GO_REF:0000037, GO:0031982=PMID:20682791, GO:0005829=Reactome:REACT_120995, GO:0030426=GO_REF:0000019, GO:0019886=Reactome:REACT_121399, GO:0005737=GO_REF:0000052, GO:0003774=GO_REF:0000037, GO:0007067=PMID:8647893, GO:0030286=GO_REF:0000037, GO:0016020=GO_REF:0000039, GO:0000086=Reactome:REACT_2203, GO:0000776=PMID:8647893, GO:0000278=Reactome:REACT_152, GO:0007017=GO_REF:0000002, GO:0007052=GO_REF:0000019, GO:0005869=PMID:8647893} Q13561 Dynactin subunit 2 protein 20120912 {GO:0005515=IPI, GO:0005813=IDA, GO:0008283=IMP, GO:0005874=IEA, GO:0031982=IDA, GO:0005829=TAS, GO:0030426=IEA, GO:0019886=TAS, GO:0005737=IDA, GO:0003774=IEA, GO:0007067=IMP, GO:0030286=IEA, GO:0016020=IEA, GO:0000086=TAS, GO:0000776=IDA, GO:0000278=TAS, GO:0007017=IEA, GO:0007052=IEA, GO:0005869=IDA} G2/M transition of mitotic cell cycle, antigen processing and presentation of exogenous peptide antigen via MHC class II, cell proliferation, microtubule-based process, mitosis, mitotic cell cycle, mitotic spindle organization centrosome, cytoplasm, cytosol, dynactin complex, dynein complex, growth cone, kinetochore, membrane, microtubule, vesicle motor activity, protein binding Human DCTN3 Reactome UniProtKB {GO:0005515=PMID:9722614, GO:0048471=PMID:9722614, GO:0005813=PMID:21399614, GO:0005819=GO_REF:0000039, GO:0030496=GO_REF:0000039, GO:0032154=GO_REF:0000039, GO:0005829=Reactome:REACT_120995, GO:0019886=Reactome:REACT_121399, GO:0000910=PMID:9722614, GO:0007067=GO_REF:0000037, GO:0005198=PMID:9722614, GO:0000086=Reactome:REACT_2203, GO:0000777=GO_REF:0000039, GO:0007017=GO_REF:0000019, GO:0005869=PMID:9722614, GO:0000278=Reactome:REACT_152} O75935 Dynactin subunit 3 protein 20130301 {GO:0005515=IPI, GO:0048471=IDA, GO:0005813=IDA, GO:0005819=IEA, GO:0030496=IEA, GO:0032154=IEA, GO:0005829=TAS, GO:0019886=TAS, GO:0000910=IDA, GO:0007067=IEA, GO:0005198=TAS, GO:0000086=TAS, GO:0000777=IEA, GO:0007017=IEA, GO:0005869=IPI, GO:0000278=TAS} G2/M transition of mitotic cell cycle, antigen processing and presentation of exogenous peptide antigen via MHC class II, cytokinesis, microtubule-based process, mitosis, mitotic cell cycle centrosome, cleavage furrow, condensed chromosome kinetochore, cytosol, dynactin complex, midbody, perinuclear region of cytoplasm, spindle protein binding, structural molecule activity Human DCTN4 Reactome UniProtKB {GO:0019886=Reactome:REACT_121399, GO:0005737=PMID:10671518, GO:0005813=PMID:21399614, GO:0047485=PMID:16554302, GO:0005634=PMID:10671518, GO:0005829=Reactome:REACT_120995} Q9UJW0 Dynactin subunit 4 protein 20130301 {GO:0019886=TAS, GO:0005737=TAS, GO:0005813=IDA, GO:0047485=IPI, GO:0005634=TAS, GO:0005829=TAS} antigen processing and presentation of exogenous peptide antigen via MHC class II centrosome, cytoplasm, cytosol, nucleus protein N-terminus binding Human DCTN5 Reactome UniProtKB {GO:0019886=Reactome:REACT_121399, GO:0005813=PMID:21399614, GO:0016740=GO_REF:0000002, GO:0005829=Reactome:REACT_120995} Q9BTE1 Dynactin subunit 5 protein 20130301 {GO:0019886=TAS, GO:0005813=IDA, GO:0016740=IEA, GO:0005829=TAS} antigen processing and presentation of exogenous peptide antigen via MHC class II centrosome, cytosol transferase activity Human DCTN6 Reactome UniProtKB {GO:0019886=Reactome:REACT_121399, GO:0005813=PMID:21399614, GO:0045502=GO_REF:0000019, GO:0005869=GO_REF:0000019, GO:0016740=GO_REF:0000002, GO:0005829=Reactome:REACT_120995} O00399 Dynactin subunit 6 protein 20130301 {GO:0019886=TAS, GO:0005813=IDA, GO:0045502=IEA, GO:0005869=IEA, GO:0016740=IEA, GO:0005829=TAS} antigen processing and presentation of exogenous peptide antigen via MHC class II centrosome, cytosol, dynactin complex dynein binding, transferase activity Human DCTPP1 UniProtKB UniProtKB {GO:0032556=GO_REF:0000019, GO:0000287=GO_REF:0000024, GO:0051289=GO_REF:0000019, GO:0047429=GO_REF:0000024, GO:0009143=GO_REF:0000024, GO:0047840=GO_REF:0000003, GO:0005829=GO_REF:0000024} Q9H773 dCTP pyrophosphatase 1 protein 20100521 {GO:0032556=IEA, GO:0000287=ISS, GO:0051289=IEA, GO:0047429=ISS, GO:0009143=ISS, GO:0047840=IEA, GO:0005829=ISS} nucleoside triphosphate catabolic process, protein homotetramerization cytosol dCTP diphosphatase activity, magnesium ion binding, nucleoside-triphosphate diphosphatase activity, pyrimidine deoxyribonucleotide binding Human UniProtKB:Q9QY93 DCUN1D1 UniProtKB UniProtKB {GO:0005515=PMID:18826954, GO:0008150=GO_REF:0000015, GO:0000151=PMID:18826954} Q96GG9 DCN1-like protein 1 protein 20100628 {GO:0005515=IPI, GO:0008150=ND, GO:0000151=IDA} biological_process ubiquitin ligase complex protein binding Human UniProtKB:Q86VP6 DCUN1D2 null null {} null null null null {} null null null DCUN1D3 UniProtKB UniProtKB {GO:0003674=GO_REF:0000015, GO:0030308=PMID:18823379, GO:0010225=PMID:18823379, GO:0048471=PMID:18823379, GO:0043065=PMID:18823379, GO:0010332=PMID:18823379, GO:0045749=PMID:18823379} Q8IWE4 DCN1-like protein 3 protein 20090731 {GO:0003674=ND, GO:0030308=IMP, GO:0010225=IDA, GO:0048471=IDA, GO:0043065=IMP, GO:0010332=IDA, GO:0045749=IMP} negative regulation of S phase of mitotic cell cycle, negative regulation of cell growth, positive regulation of apoptotic process, response to UV-C, response to gamma radiation perinuclear region of cytoplasm molecular_function Human DCUN1D4 UniProtKB UniProtKB {GO:0003674=GO_REF:0000015, GO:0008150=GO_REF:0000015, GO:0005634=GO_REF:0000054, GO:0005575=GO_REF:0000015} Q92564 DCN1-like protein 4 protein 20100930 {GO:0003674=ND, GO:0008150=ND, GO:0005634=IDA, GO:0005575=ND} biological_process cellular_component, nucleus molecular_function Human DCUN1D5 UniProtKB UniProtKB {GO:0003674=GO_REF:0000015, GO:0008150=GO_REF:0000015, GO:0005575=GO_REF:0000015} Q9BTE7 DCN1-like protein 5 protein 20101020 {GO:0003674=ND, GO:0008150=ND, GO:0005575=ND} biological_process cellular_component molecular_function Human DCX Reactome UniProtKB {GO:0008017=PMID:14741102, GO:0043005=PMID:14741102, GO:0019901=PMID:14741102, GO:0005875=PMID:11001923, GO:0005874=GO_REF:0000037, GO:0021952=GO_REF:0000019, GO:0048675=GO_REF:0000019, GO:0007417=PMID:9489699, GO:0005829=Reactome:REACT_22218, GO:0007399=PMID:9489699, GO:0035556=GO_REF:0000002, GO:0005622=GO_REF:0000019, GO:0048813=GO_REF:0000019, GO:0007411=Reactome:REACT_18266, GO:0007420=GO_REF:0000019, GO:0001764=PMID:14741102, GO:0005856=PMID:11001923} O43602 Neuronal migration protein doublecortin protein 20090729 {GO:0008017=IDA, GO:0043005=IDA, GO:0019901=IPI, GO:0005875=TAS, GO:0005874=IEA, GO:0021952=IEA, GO:0048675=IEA, GO:0007417=TAS, GO:0005829=TAS, GO:0007399=TAS, GO:0035556=IEA, GO:0005622=IEA, GO:0048813=IEA, GO:0007411=TAS, GO:0007420=IEA, GO:0001764=IDA, GO:0005856=TAS} axon extension, axon guidance, brain development, central nervous system development, central nervous system projection neuron axonogenesis, dendrite morphogenesis, intracellular signal transduction, nervous system development, neuron migration cytoskeleton, cytosol, intracellular, microtubule, microtubule associated complex, neuron projection microtubule binding, protein kinase binding Human DCXR UniProtKB UniProtKB {GO:0005903=GO_REF:0000019, GO:0005881=PMID:23264731, GO:0005997=PMID:11882650, GO:0005902=GO_REF:0000019, GO:0016020=GO_REF:0000039, GO:0051289=PMID:11882650, GO:0016491=GO_REF:0000002, GO:0006006=PMID:11882650, GO:0006739=GO_REF:0000019, GO:0050038=PMID:11882650, GO:0055114=PMID:19442656, GO:0042732=GO_REF:0000037} Q7Z4W1 L-xylulose reductase protein 20130311 {GO:0005903=IEA, GO:0005881=IDA, GO:0005997=IDA, GO:0005902=IEA, GO:0016020=IEA, GO:0051289=IDA, GO:0016491=IEA, GO:0006006=IDA, GO:0006739=IEA, GO:0050038=IDA, GO:0055114=IDA, GO:0042732=IEA} D-xylose metabolic process, NADP metabolic process, glucose metabolic process, oxidation-reduction process, protein homotetramerization, xylulose metabolic process brush border, cytoplasmic microtubule, membrane, microvillus L-xylulose reductase (NADP+) activity, oxidoreductase activity Human DDA1 null null {} null null null null {} null null null DDAH1 BHF-UCL UniProtKB {GO:0007263=PMID:9874257, GO:0016813=GO_REF:0000002, GO:0003824=PMID:9874257, GO:0046872=GO_REF:0000037, GO:0045766=GO_REF:0000019, GO:0045429=GO_REF:0000024, GO:0005739=GO_REF:0000019, GO:0003073=GO_REF:0000024, GO:0005737=GO_REF:0000002, GO:0000052=PMID:19663506, GO:0006527=PMID:9874257, GO:0016597=GO_REF:0000019, GO:0016403=PMID:19663506} O94760 N(G),N(G)-dimethylarginine dimethylaminohydrolase 1 protein 20120111 {GO:0007263=TAS, GO:0016813=IEA, GO:0003824=TAS, GO:0046872=IEA, GO:0045766=IEA, GO:0045429=ISS, GO:0005739=IEA, GO:0003073=ISS, GO:0005737=IEA, GO:0000052=IDA, GO:0006527=TAS, GO:0016597=IEA, GO:0016403=IDA} arginine catabolic process, citrulline metabolic process, nitric oxide mediated signal transduction, positive regulation of angiogenesis, positive regulation of nitric oxide biosynthetic process, regulation of systemic arterial blood pressure cytoplasm, mitochondrion amino acid binding, catalytic activity, dimethylargininase activity, hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines, metal ion binding Human UniProtKB:Q9CWS0 DDAH2 ENSEMBL UniProtKB {GO:0005515=PMID:19060904, GO:0043066=PMID:16130169, GO:0007263=PMID:10493931, GO:0016813=GO_REF:0000002, GO:0003824=PMID:10493931, GO:0045429=GO_REF:0000024, GO:0006809=PMID:10493931, GO:0005739=GO_REF:0000039, GO:0005737=GO_REF:0000002, GO:0006525=GO_REF:0000019, GO:0000052=PMID:10493931, GO:0006527=PMID:10493931, GO:0016597=GO_REF:0000019, GO:0016403=PMID:10493931} Q5SSV3 N(G),N(G)-dimethylarginine dimethylaminohydrolase 2 protein 20130413 {GO:0005515=IPI, GO:0043066=TAS, GO:0007263=TAS, GO:0016813=IEA, GO:0003824=TAS, GO:0045429=ISS, GO:0006809=TAS, GO:0005739=IEA, GO:0005737=IEA, GO:0006525=IEA, GO:0000052=IDA, GO:0006527=TAS, GO:0016597=IEA, GO:0016403=IDA} arginine catabolic process, arginine metabolic process, citrulline metabolic process, negative regulation of apoptotic process, nitric oxide biosynthetic process, nitric oxide mediated signal transduction, positive regulation of nitric oxide biosynthetic process cytoplasm, mitochondrion amino acid binding, catalytic activity, dimethylargininase activity, hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines, protein binding Human Ensembl:ENSRNOP00000001118 DDB1 IntAct UniProtKB {GO:0005515=PMID:23238014, GO:0005634=PMID:20223979, GO:0080008=PMID:18381890, GO:0003676=GO_REF:0000002, GO:0003677=PMID:8798680, GO:0003684=PMID:8407967, GO:0005737=PMID:20223979, GO:0006281=Reactome:REACT_216, GO:0042787=PMID:11673459, GO:0019048=GO_REF:0000037, GO:0000075=PMID:17088560, GO:0031465=PMID:18794347, GO:0043161=PMID:20223979, GO:0005654=Reactome:REACT_2163, GO:0006289=Reactome:REACT_1826, GO:0031464=PMID:20223979, GO:0000718=Reactome:REACT_311, GO:0016055=GO_REF:0000019} Q16531 DNA damage-binding protein 1 protein 20130415 {GO:0005515=IPI, GO:0005634=IDA, GO:0080008=IDA, GO:0003676=IEA, GO:0003677=TAS, GO:0003684=TAS, GO:0005737=IDA, GO:0006281=TAS, GO:0042787=IDA, GO:0019048=IEA, GO:0000075=IMP, GO:0031465=IDA, GO:0043161=IMP, GO:0005654=TAS, GO:0006289=TAS, GO:0031464=IDA, GO:0000718=TAS, GO:0016055=IEA} DNA repair, Wnt receptor signaling pathway, cell cycle checkpoint, nucleotide-excision repair, nucleotide-excision repair, DNA damage removal, proteasomal ubiquitin-dependent protein catabolic process, protein ubiquitination involved in ubiquitin-dependent protein catabolic process, virus-host interaction Cul4-RING ubiquitin ligase complex, Cul4A-RING ubiquitin ligase complex, Cul4B-RING ubiquitin ligase complex, cytoplasm, nucleoplasm, nucleus DNA binding, damaged DNA binding, nucleic acid binding, protein binding Human UniProtKB:O75530 DDB2 IntAct UniProtKB {GO:0005515=PMID:19109893, GO:0000209=PMID:12732143, GO:0004842=PMID:12732143, GO:0003677=PMID:8798680, GO:0051865=PMID:12732143, GO:0003684=PMID:8407967, GO:0043234=PMID:12732143, GO:0006290=GO_REF:0000019, GO:0006281=Reactome:REACT_216, GO:0005654=Reactome:REACT_2163, GO:0006289=Reactome:REACT_1826, GO:0000718=Reactome:REACT_311, GO:0009411=PMID:12732143} Q92466 DNA damage-binding protein 2 protein 20130415 {GO:0005515=IPI, GO:0000209=IDA, GO:0004842=IDA, GO:0003677=TAS, GO:0051865=IDA, GO:0003684=TAS, GO:0043234=IDA, GO:0006290=IEA, GO:0006281=TAS, GO:0005654=TAS, GO:0006289=TAS, GO:0000718=TAS, GO:0009411=IDA} DNA repair, nucleotide-excision repair, nucleotide-excision repair, DNA damage removal, protein autoubiquitination, protein polyubiquitination, pyrimidine dimer repair, response to UV nucleoplasm, protein complex DNA binding, damaged DNA binding, protein binding, ubiquitin-protein ligase activity Human UniProtKB:Q16531 DDC IntAct UniProtKB {GO:0005515=PMID:12864730, GO:0030424=GO_REF:0000019, GO:0046684=GO_REF:0000019, GO:0010259=GO_REF:0000019, GO:0044281=Reactome:REACT_111217, GO:0005829=Reactome:REACT_15546, GO:0042416=GO_REF:0000041, GO:0034641=Reactome:REACT_13, GO:0043025=GO_REF:0000019, GO:0033076=GO_REF:0000019, GO:0006520=GO_REF:0000002, GO:0019904=GO_REF:0000019, GO:0071312=GO_REF:0000019, GO:0035690=GO_REF:0000019, GO:0008021=GO_REF:0000019, GO:0042427=GO_REF:0000019, GO:0071363=GO_REF:0000019, GO:0046219=Reactome:REACT_15439, GO:0052314=GO_REF:0000019, GO:0030170=GO_REF:0000002, GO:0004058=Reactome:REACT_15546, GO:0016831=GO_REF:0000002, GO:0007623=GO_REF:0000019, GO:0016597=GO_REF:0000019, GO:0015842=GO_REF:0000019, GO:0042423=Reactome:REACT_15551} P20711 Aromatic-L-amino-acid decarboxylase protein 20130415 {GO:0005515=IPI, GO:0030424=IEA, GO:0046684=IEA, GO:0010259=IEA, GO:0044281=TAS, GO:0005829=TAS, GO:0042416=IEA, GO:0034641=TAS, GO:0043025=IEA, GO:0033076=IEA, GO:0006520=IEA, GO:0019904=IEA, GO:0071312=IEA, GO:0035690=IEA, GO:0008021=IEA, GO:0042427=IEA, GO:0071363=IEA, GO:0046219=TAS, GO:0052314=IEA, GO:0030170=IEA, GO:0004058=TAS, GO:0016831=IEA, GO:0007623=IEA, GO:0016597=IEA, GO:0015842=IEA, GO:0042423=TAS} catecholamine biosynthetic process, cellular amino acid metabolic process, cellular nitrogen compound metabolic process, cellular response to alkaloid, cellular response to drug, cellular response to growth factor stimulus, circadian rhythm, dopamine biosynthetic process, indolalkylamine biosynthetic process, isoquinoline alkaloid metabolic process, multicellular organismal aging, phytoalexin metabolic process, response to pyrethroid, serotonin biosynthetic process, small molecule metabolic process, synaptic vesicle amine transport axon, cytosol, neuronal cell body, synaptic vesicle amino acid binding, aromatic-L-amino-acid decarboxylase activity, carboxy-lyase activity, protein binding, protein domain specific binding, pyridoxal phosphate binding Human UniProtKB:P10275 DDHD1 UniProtKB UniProtKB {GO:0016042=GO_REF:0000037, GO:0005737=GO_REF:0000039, GO:0016787=GO_REF:0000037, GO:0046872=GO_REF:0000002} Q8NEL9 Phospholipase DDHD1 protein 20130413 {GO:0016042=IEA, GO:0005737=IEA, GO:0016787=IEA, GO:0046872=IEA} lipid catabolic process cytoplasm hydrolase activity, metal ion binding Human UniProtKB-SubCell:SL-0086 DDHD2 HPA UniProtKB {GO:0016042=GO_REF:0000037, GO:0005793=GO_REF:0000039, GO:0005813=GO_REF:0000052, GO:0005737=GO_REF:0000052, GO:0005794=GO_REF:0000039, GO:0016787=GO_REF:0000037, GO:0046872=GO_REF:0000002, GO:0005829=GO_REF:0000039} O94830 Phospholipase DDHD2 protein 20100326 {GO:0016042=IEA, GO:0005793=IEA, GO:0005813=IDA, GO:0005737=IDA, GO:0005794=IEA, GO:0016787=IEA, GO:0046872=IEA, GO:0005829=IEA} lipid catabolic process Golgi apparatus, centrosome, cytoplasm, cytosol, endoplasmic reticulum-Golgi intermediate compartment hydrolase activity, metal ion binding Human DDI1 InterPro UniProtKB {GO:0006508=GO_REF:0000002, GO:0004190=GO_REF:0000002} Q8WTU0 Protein DDI1 homolog 1 protein 20130413 {GO:0006508=IEA, GO:0004190=IEA} proteolysis aspartic-type endopeptidase activity Human InterPro:IPR019103 DDI2 InterPro UniProtKB {GO:0006508=GO_REF:0000002, GO:0004190=GO_REF:0000002} Q5TDH0 Protein DDI1 homolog 2 protein 20130413 {GO:0006508=IEA, GO:0004190=IEA} proteolysis aspartic-type endopeptidase activity Human InterPro:IPR019103 DDIT3 BHF-UCL UniProtKB {GO:0005515=PMID:15775988, GO:0006986=PMID:18940792, GO:0034976=PMID:19061639, GO:0006983=GO_REF:0000019, GO:0003700=GO_REF:0000002, GO:0005634=PMID:22761832, GO:0043620=PMID:19816510, GO:0043433=PMID:16434966, GO:0045662=GO_REF:0000019, GO:0032757=PMID:20829347, GO:0030968=Reactome:REACT_18356, GO:0005737=GO_REF:0000039, GO:0043525=GO_REF:0000019, GO:0045944=PMID:22065586, GO:0042789=PMID:14667815, GO:0007050=GO_REF:0000037, GO:0016055=GO_REF:0000037, GO:0090090=PMID:16434966, GO:0006355=PMID:22761832, GO:0051209=GO_REF:0000019, GO:2000016=PMID:16434966, GO:0003714=PMID:7503811, GO:0044324=PMID:16434966, GO:0003677=PMID:14667815, GO:0006974=PMID:1339368, GO:0043565=GO_REF:0000002, GO:0070059=PMID:15322075, GO:0005654=Reactome:REACT_115551, GO:0045454=PMID:14667815, GO:0043161=PMID:17872950, GO:0006987=Reactome:REACT_18348, GO:0045893=PMID:15775988, GO:0044267=Reactome:REACT_17015, GO:0001955=GO_REF:0000019, GO:0045892=PMID:18940792, GO:0008134=PMID:16434966} P35638 DNA damage-inducible transcript 3 protein protein 20100715 {GO:0005515=IPI, GO:0006986=IDA, GO:0034976=IDA, GO:0006983=IEA, GO:0003700=IEA, GO:0005634=IDA, GO:0043620=TAS, GO:0043433=IDA, GO:0045662=IEA, GO:0032757=IMP, GO:0030968=TAS, GO:0005737=IEA, GO:0043525=IEA, GO:0045944=IMP, GO:0042789=IDA, GO:0007050=IEA, GO:0016055=IEA, GO:0090090=ISS, GO:0006355=IMP, GO:0051209=IEA, GO:2000016=IDA, GO:0003714=TAS, GO:0044324=ISS, GO:0003677=IDA, GO:0006974=TAS, GO:0043565=IEA, GO:0070059=IMP, GO:0005654=TAS, GO:0045454=IDA, GO:0043161=IDA, GO:0006987=TAS, GO:0045893=IDA, GO:0044267=TAS, GO:0001955=IEA, GO:0045892=IDA, GO:0008134=IPI} ER overload response, Wnt receptor signaling pathway, activation of signaling protein activity involved in unfolded protein response, blood vessel maturation, cell cycle arrest, cell redox homeostasis, cellular protein metabolic process, endoplasmic reticulum unfolded protein response, intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress, mRNA transcription from RNA polymerase II promoter, negative regulation of canonical Wnt receptor signaling pathway, negative regulation of determination of dorsal identity, negative regulation of myoblast differentiation, negative regulation of sequence-specific DNA binding transcription factor activity, negative regulation of transcription, DNA-dependent, positive regulation of interleukin-8 production, positive regulation of neuron apoptotic process, positive regulation of transcription from RNA polymerase II promoter, positive regulation of transcription, DNA-dependent, proteasomal ubiquitin-dependent protein catabolic process, regulation of DNA-dependent transcription in response to stress, regulation of transcription involved in anterior/posterior axis specification, regulation of transcription, DNA-dependent, release of sequestered calcium ion into cytosol, response to DNA damage stimulus, response to endoplasmic reticulum stress, response to unfolded protein cytoplasm, nucleoplasm, nucleus DNA binding, protein binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, transcription corepressor activity, transcription factor binding Human DDIT4 HPA UniProtKB {GO:0010741=GO_REF:0000024, GO:0001666=PMID:20166753, GO:0032007=PMID:20166753, GO:0048011=GO_REF:0000024, GO:0008283=GO_REF:0000024, GO:0072593=GO_REF:0000019, GO:0043241=GO_REF:0000019, GO:1901216=GO_REF:0000024, GO:0010801=GO_REF:0000024, GO:0005829=GO_REF:0000039, GO:0005622=GO_REF:0000054, GO:0005739=GO_REF:0000039, GO:0042771=GO_REF:0000024, GO:0071889=GO_REF:0000019, GO:0051607=GO_REF:0000037, GO:0005737=GO_REF:0000052, GO:0007420=GO_REF:0000024, GO:0033137=GO_REF:0000024, GO:0030182=GO_REF:0000024, GO:0045820=GO_REF:0000019, GO:0001764=GO_REF:0000024} Q9NX09 DNA damage-inducible transcript 4 protein protein 20101115 {GO:0010741=ISS, GO:0001666=IDA, GO:0032007=IMP, GO:0048011=ISS, GO:0008283=ISS, GO:0072593=IEA, GO:0043241=IEA, GO:1901216=ISS, GO:0010801=ISS, GO:0005829=IEA, GO:0005622=IDA, GO:0005739=IEA, GO:0042771=ISS, GO:0071889=IEA, GO:0051607=IEA, GO:0005737=IDA, GO:0007420=ISS, GO:0033137=ISS, GO:0030182=ISS, GO:0045820=IEA, GO:0001764=ISS} brain development, cell proliferation, defense response to virus, intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator, negative regulation of TOR signaling cascade, negative regulation of glycolysis, negative regulation of intracellular protein kinase cascade, negative regulation of peptidyl-serine phosphorylation, negative regulation of peptidyl-threonine phosphorylation, neuron differentiation, neuron migration, neurotrophin TRK receptor signaling pathway, positive regulation of neuron death, protein complex disassembly, reactive oxygen species metabolic process, response to hypoxia cytoplasm, cytosol, intracellular, mitochondrion 14-3-3 protein binding Human DDIT4L UniProtKB UniProtKB {GO:0005737=GO_REF:0000024, GO:0009968=GO_REF:0000002} Q96D03 DNA damage-inducible transcript 4-like protein protein 20071012 {GO:0005737=ISS, GO:0009968=IEA} negative regulation of signal transduction cytoplasm Human UniProtKB:Q9NX09 DDN IntAct UniProtKB {GO:0005515=PMID:16751601, GO:0005737=PMID:16464232, GO:0032591=GO_REF:0000039, GO:0005789=GO_REF:0000039, GO:0043204=GO_REF:0000039, GO:0005634=GO_REF:0000039, GO:0042995=PMID:16464232} O94850 Dendrin protein 20130415 {GO:0005515=IPI, GO:0005737=IDA, GO:0032591=IEA, GO:0005789=IEA, GO:0043204=IEA, GO:0005634=IEA, GO:0042995=IDA} cell projection, cytoplasm, dendritic spine membrane, endoplasmic reticulum membrane, nucleus, perikaryon protein binding Human UniProtKB:Q96B97 DDO UniProtKB UniProtKB {GO:0005515=PMID:9820813, GO:0007320=GO_REF:0000019, GO:0048037=PMID:20603179, GO:0016641=GO_REF:0000002, GO:0006531=GO_REF:0000019, GO:0005102=PMID:20178365, GO:0042445=GO_REF:0000019, GO:0007625=GO_REF:0000019, GO:0003884=GO_REF:0000002, GO:0019478=PMID:20603179, GO:0005777=PMID:9820813} Q99489 D-aspartate oxidase protein 20120427 {GO:0005515=IPI, GO:0007320=IEA, GO:0048037=IDA, GO:0016641=IEA, GO:0006531=IEA, GO:0005102=IPI, GO:0042445=IEA, GO:0007625=IEA, GO:0003884=IEA, GO:0019478=IDA, GO:0005777=NAS} D-amino acid catabolic process, aspartate metabolic process, grooming behavior, hormone metabolic process, insemination peroxisome D-amino-acid oxidase activity, cofactor binding, oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor, protein binding, receptor binding Human UniProtKB:P50542 DDOST IntAct UniProtKB {GO:0005515=PMID:21903422, GO:0004576=GO_REF:0000024, GO:0010467=Reactome:REACT_71, GO:0006614=Reactome:REACT_115902, GO:0006412=Reactome:REACT_1014, GO:0043231=PMID:9642163, GO:0043234=PMID:9642163, GO:0042110=PMID:9642163, GO:0045087=Reactome:REACT_6802, GO:0004579=PMID:15835887, GO:0005789=Reactome:REACT_22208, GO:0006486=GO_REF:0000024, GO:0016021=GO_REF:0000037, GO:0006487=PMID:9642163, GO:0034097=PMID:9642163, GO:0008250=PMID:15835887, GO:0044267=Reactome:REACT_17015, GO:0043687=Reactome:REACT_22161, GO:0018279=Reactome:REACT_22426} P39656 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit protein 20130415 {GO:0005515=IPI, GO:0004576=ISS, GO:0010467=TAS, GO:0006614=TAS, GO:0006412=TAS, GO:0043231=IDA, GO:0043234=IDA, GO:0042110=IDA, GO:0045087=TAS, GO:0004579=IC, GO:0005789=TAS, GO:0006486=ISS, GO:0016021=IEA, GO:0006487=IDA, GO:0034097=IDA, GO:0008250=TAS, GO:0044267=TAS, GO:0043687=TAS, GO:0018279=TAS} SRP-dependent cotranslational protein targeting to membrane, T cell activation, cellular protein metabolic process, gene expression, innate immune response, post-translational protein modification, protein N-linked glycosylation, protein N-linked glycosylation via asparagine, protein glycosylation, response to cytokine stimulus, translation endoplasmic reticulum membrane, integral to membrane, intracellular membrane-bounded organelle, oligosaccharyltransferase complex, protein complex dolichyl-diphosphooligosaccharide-protein glycotransferase activity, oligosaccharyl transferase activity, protein binding Human UniProtKB:Q86WV6 DDR1 InterPro UniProtKB {GO:0044319=PMID:12065315, GO:0005515=PMID:18190796, GO:0008285=GO_REF:0000019, GO:0005886=GO_REF:0000019, GO:0005518=PMID:9659899, GO:0001558=GO_REF:0000019, GO:0046872=GO_REF:0000037, GO:0043583=GO_REF:0000019, GO:0010715=PMID:12065315, GO:0046777=PMID:9659899, GO:0007155=PMID:8302582, GO:0038083=PMID:21044884, GO:0007566=GO_REF:0000019, GO:0014909=PMID:12065315, GO:0018108=GO_REF:0000019, GO:0005576=GO_REF:0000039, GO:0038063=PMID:9659899, GO:0005524=GO_REF:0000002, GO:0038062=PMID:9659899, GO:0061302=PMID:12065315, GO:0004672=GO_REF:0000002, GO:0016020=GO_REF:0000002, GO:0007595=GO_REF:0000037, GO:0005887=PMID:8390675, GO:0001952=GO_REF:0000019, GO:0004714=PMID:9659899, GO:0007169=GO_REF:0000002, GO:0060444=GO_REF:0000019, GO:0060749=GO_REF:0000019} Q6ZNR9 Epithelial discoidin domain-containing receptor 1 protein 20130413 {GO:0044319=IMP, GO:0005515=IPI, GO:0008285=IEA, GO:0005886=IEA, GO:0005518=IDA, GO:0001558=IEA, GO:0046872=IEA, GO:0043583=IEA, GO:0010715=IMP, GO:0046777=IDA, GO:0007155=TAS, GO:0038083=IDA, GO:0007566=IEA, GO:0014909=IMP, GO:0018108=IEA, GO:0005576=IEA, GO:0038063=IDA, GO:0005524=IEA, GO:0038062=IDA, GO:0061302=IMP, GO:0004672=IEA, GO:0016020=IEA, GO:0007595=IEA, GO:0005887=TAS, GO:0001952=IEA, GO:0004714=TAS, GO:0007169=IEA, GO:0060444=IEA, GO:0060749=IEA} branching involved in mammary gland duct morphogenesis, cell adhesion, collagen-activated tyrosine kinase receptor signaling pathway, ear development, embryo implantation, lactation, mammary gland alveolus development, negative regulation of cell proliferation, peptidyl-tyrosine autophosphorylation, peptidyl-tyrosine phosphorylation, protein autophosphorylation, regulation of cell growth, regulation of cell-matrix adhesion, regulation of extracellular matrix disassembly, smooth muscle cell migration, smooth muscle cell-matrix adhesion, transmembrane receptor protein tyrosine kinase signaling pathway, wound healing, spreading of cells extracellular region, integral to plasma membrane, membrane, plasma membrane ATP binding, collagen binding, metal ion binding, protein binding, protein kinase activity, protein tyrosine kinase collagen receptor activity, transmembrane receptor protein tyrosine kinase activity Human InterPro:IPR000719 DDR2 ENSEMBL UniProtKB {GO:0005515=PMID:22939624, GO:0030500=PMID:20564243, GO:0003416=GO_REF:0000019, GO:0005518=PMID:20004161, GO:0018108=PMID:20004161, GO:0048146=GO_REF:0000019, GO:0038063=PMID:16186108, GO:0031214=GO_REF:0000019, GO:0005524=GO_REF:0000037, GO:0035988=GO_REF:0000019, GO:0038062=GO_REF:0000019, GO:0010715=PMID:16626936, GO:0045669=PMID:20564243, GO:0007165=PMID:9659899, GO:0051091=PMID:20564243, GO:0046777=PMID:16186108, GO:0010763=GO_REF:0000019, GO:0001503=GO_REF:0000037, GO:0005887=PMID:9659899, GO:0030199=GO_REF:0000019, GO:0045860=PMID:20564243, GO:0090091=GO_REF:0000019, GO:0007155=GO_REF:0000002, GO:0004714=PMID:20004161} Q5T245 Discoidin domain-containing receptor 2 protein 20130413 {GO:0005515=IPI, GO:0030500=IMP, GO:0003416=IEA, GO:0005518=IDA, GO:0018108=IDA, GO:0048146=IEA, GO:0038063=IDA, GO:0031214=IEA, GO:0005524=IEA, GO:0035988=IEA, GO:0038062=IEA, GO:0010715=TAS, GO:0045669=IMP, GO:0007165=TAS, GO:0051091=IMP, GO:0046777=IDA, GO:0010763=IEA, GO:0001503=IEA, GO:0005887=TAS, GO:0030199=IEA, GO:0045860=IMP, GO:0090091=IEA, GO:0007155=IEA, GO:0004714=IDA} biomineral tissue development, cell adhesion, chondrocyte proliferation, collagen fibril organization, collagen-activated tyrosine kinase receptor signaling pathway, endochondral bone growth, ossification, peptidyl-tyrosine phosphorylation, positive regulation of extracellular matrix disassembly, positive regulation of fibroblast migration, positive regulation of fibroblast proliferation, positive regulation of osteoblast differentiation, positive regulation of protein kinase activity, positive regulation of sequence-specific DNA binding transcription factor activity, protein autophosphorylation, regulation of bone mineralization, regulation of extracellular matrix disassembly, signal transduction integral to plasma membrane ATP binding, collagen binding, protein binding, protein tyrosine kinase collagen receptor activity, transmembrane receptor protein tyrosine kinase activity Human Ensembl:ENSMUSP00000129624 DDRGK1 UniProtKB UniProtKB {GO:0005515=PMID:20018847, GO:0005783=PMID:20018847} Q96HY6 DDRGK domain-containing protein 1 protein 20100204 {GO:0005515=IPI, GO:0005783=IDA} endoplasmic reticulum protein binding Human UniProtKB:Q9Y3C8 DDT PINC UniProtKB {GO:0005737=GO_REF:0000039, GO:0004167=PMID:9480844, GO:0033981=GO_REF:0000003, GO:0042438=GO_REF:0000037} P30046 D-dopachrome decarboxylase protein 20030904 {GO:0005737=IEA, GO:0004167=TAS, GO:0033981=IEA, GO:0042438=IEA} melanin biosynthetic process cytoplasm D-dopachrome decarboxylase activity, dopachrome isomerase activity Human DDTL UniProtKB UniProtKB {GO:0005737=GO_REF:0000039, GO:0016829=GO_REF:0000037} A6NHG4 D-dopachrome decarboxylase-like protein protein 20130413 {GO:0005737=IEA, GO:0016829=IEA} cytoplasm lyase activity Human UniProtKB-SubCell:SL-0086 DDX1 GOC UniProtKB {GO:0005515=PMID:18335541, GO:0003725=GO_REF:0000019, GO:0003724=PMID:7689221, GO:0090305=PMID:18710941, GO:0010494=PMID:18335541, GO:0005634=GO_REF:0000052, GO:0071920=PMID:11598190, GO:0072669=PMID:21311021, GO:0006302=PMID:18710941, GO:0005737=GO_REF:0000052, GO:0004527=GO_REF:0000037, GO:0008143=PMID:12183465, GO:0032508=PMID:18710941, GO:0003712=PMID:19058135, GO:0008026=PMID:12183465, GO:0000245=PMID:7689221, GO:0006355=GO_REF:0000037, GO:0033677=PMID:18710941, GO:0005730=GO_REF:0000052, GO:0007275=PMID:7689221, GO:0009615=GO_REF:0000019, GO:0005524=GO_REF:0000037, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037, GO:0004518=PMID:18710941, GO:0030529=PMID:18809582, GO:0003682=PMID:19058135, GO:0006446=PMID:7689221, GO:0043330=GO_REF:0000019} Q92499 ATP-dependent RNA helicase DDX1 protein 20130413 {GO:0005515=IPI, GO:0003725=IEA, GO:0003724=TAS, GO:0090305=IDA, GO:0010494=IDA, GO:0005634=IDA, GO:0071920=IDA, GO:0072669=IDA, GO:0006302=IDA, GO:0005737=IDA, GO:0004527=IEA, GO:0008143=IDA, GO:0032508=IDA, GO:0003712=IDA, GO:0008026=IDA, GO:0000245=NAS, GO:0006355=IEA, GO:0033677=IDA, GO:0005730=IDA, GO:0007275=IEP, GO:0009615=IEA, GO:0005524=IEA, GO:0003677=IEA, GO:0006351=IEA, GO:0004518=IDA, GO:0030529=IDA, GO:0003682=IDA, GO:0006446=NAS, GO:0043330=IEA} DNA duplex unwinding, double-strand break repair, multicellular organismal development, nucleic acid phosphodiester bond hydrolysis, regulation of transcription, DNA-dependent, regulation of translational initiation, response to exogenous dsRNA, response to virus, spliceosomal complex assembly, transcription, DNA-dependent cleavage body, cytoplasm, cytoplasmic stress granule, nucleolus, nucleus, ribonucleoprotein complex, tRNA-splicing ligase complex ATP binding, ATP-dependent helicase activity, DNA binding, DNA/RNA helicase activity, RNA helicase activity, chromatin binding, double-stranded RNA binding, exonuclease activity, nuclease activity, poly(A) RNA binding, protein binding, transcription cofactor activity Human DDX10 PINC UniProtKB {GO:0008026=GO_REF:0000002, GO:0003724=PMID:8660968, GO:0003723=GO_REF:0000037, GO:0005524=GO_REF:0000037} Q13206 Probable ATP-dependent RNA helicase DDX10 protein 20030904 {GO:0008026=IEA, GO:0003724=TAS, GO:0003723=IEA, GO:0005524=IEA} ATP binding, ATP-dependent helicase activity, RNA binding, RNA helicase activity Human DDX11 Reactome UniProtKB {GO:0005515=PMID:17189189, GO:0000790=PMID:17105772, GO:0008284=PMID:9013641, GO:0016817=GO_REF:0000002, GO:0003723=GO_REF:0000037, GO:0005634=PMID:17189189, GO:0046872=GO_REF:0000037, GO:0030968=Reactome:REACT_18356, GO:0000084=PMID:9013641, GO:0004003=GO_REF:0000002, GO:0000086=PMID:9013641, GO:0032508=GO_REF:0000002, GO:0008094=PMID:18499658, GO:0008026=GO_REF:0000002, GO:0051539=GO_REF:0000037, GO:0005730=GO_REF:0000039, GO:0004386=PMID:18499658, GO:0030496=PMID:17105772, GO:0003676=GO_REF:0000002, GO:0005524=GO_REF:0000037, GO:0003677=GO_REF:0000037, GO:0003678=PMID:9013641, GO:0000922=PMID:17105772, GO:0000070=PMID:9013641, GO:0019048=GO_REF:0000037, GO:0007062=PMID:17105772, GO:0005654=Reactome:REACT_116074, GO:0006987=Reactome:REACT_18368, GO:0044267=Reactome:REACT_17015} Q96FC9 Probable ATP-dependent RNA helicase DDX11 protein 20130301 {GO:0005515=IPI, GO:0000790=IDA, GO:0008284=TAS, GO:0016817=IEA, GO:0003723=IEA, GO:0005634=IDA, GO:0046872=IEA, GO:0030968=TAS, GO:0000084=TAS, GO:0004003=IEA, GO:0000086=TAS, GO:0032508=IEA, GO:0008094=IDA, GO:0008026=IEA, GO:0051539=IEA, GO:0005730=IEA, GO:0004386=IDA, GO:0030496=IDA, GO:0003676=IEA, GO:0005524=IEA, GO:0003677=IEA, GO:0003678=TAS, GO:0000922=IDA, GO:0000070=TAS, GO:0019048=IEA, GO:0007062=IDA, GO:0005654=TAS, GO:0006987=TAS, GO:0044267=TAS} DNA duplex unwinding, G2/M transition of mitotic cell cycle, S phase of mitotic cell cycle, activation of signaling protein activity involved in unfolded protein response, cellular protein metabolic process, endoplasmic reticulum unfolded protein response, mitotic sister chromatid segregation, positive regulation of cell proliferation, sister chromatid cohesion, virus-host interaction midbody, nuclear chromatin, nucleolus, nucleoplasm, nucleus, spindle pole 4 iron, 4 sulfur cluster binding, ATP binding, ATP-dependent DNA helicase activity, ATP-dependent helicase activity, DNA binding, DNA helicase activity, DNA-dependent ATPase activity, RNA binding, helicase activity, hydrolase activity, acting on acid anhydrides, metal ion binding, nucleic acid binding, protein binding Human DDX17 IntAct UniProtKB {GO:0005515=PMID:22266867, GO:0008026=GO_REF:0000002, GO:0006396=PMID:8871553, GO:0003724=PMID:8871553, GO:0003723=GO_REF:0000037, GO:0003713=PMID:11250900, GO:0030331=PMID:11250900, GO:0005730=GO_REF:0000039, GO:0005634=PMID:11250900, GO:0003676=GO_REF:0000002, GO:0009791=GO_REF:0000019, GO:0005524=GO_REF:0000037, GO:0006351=GO_REF:0000037, GO:0008186=PMID:8871553, GO:0045944=PMID:11250900, GO:0033148=PMID:11250900, GO:2001014=PMID:17011493, GO:0072358=GO_REF:0000019} Q92841 Probable ATP-dependent RNA helicase DDX17 protein 20130415 {GO:0005515=IPI, GO:0008026=IEA, GO:0006396=TAS, GO:0003724=TAS, GO:0003723=IEA, GO:0003713=IDA, GO:0030331=IDA, GO:0005730=IEA, GO:0005634=IDA, GO:0003676=IEA, GO:0009791=IEA, GO:0005524=IEA, GO:0006351=IEA, GO:0008186=TAS, GO:0045944=IDA, GO:0033148=IDA, GO:2001014=IMP, GO:0072358=IEA} RNA processing, cardiovascular system development, positive regulation of intracellular estrogen receptor signaling pathway, positive regulation of transcription from RNA polymerase II promoter, post-embryonic development, regulation of skeletal muscle cell differentiation, transcription, DNA-dependent nucleolus, nucleus ATP binding, ATP-dependent helicase activity, RNA binding, RNA helicase activity, RNA-dependent ATPase activity, estrogen receptor binding, nucleic acid binding, protein binding, transcription coactivator activity Human UniProtKB:O94916 DDX18 PINC UniProtKB {GO:0004004=PMID:8861962, GO:0005515=PMID:16963496, GO:0008026=GO_REF:0000002, GO:0003723=GO_REF:0000037, GO:0005730=PMID:16963496, GO:0003676=GO_REF:0000002, GO:0005524=GO_REF:0000037} Q9NVP1 ATP-dependent RNA helicase DDX18 protein 20030904 {GO:0004004=TAS, GO:0005515=IPI, GO:0008026=IEA, GO:0003723=IEA, GO:0005730=IDA, GO:0003676=IEA, GO:0005524=IEA} nucleolus ATP binding, ATP-dependent RNA helicase activity, ATP-dependent helicase activity, RNA binding, nucleic acid binding, protein binding Human DDX19A UniProtKB UniProtKB {GO:0008026=GO_REF:0000002, GO:0031965=GO_REF:0000039, GO:0005737=GO_REF:0000039, GO:0005643=GO_REF:0000039, GO:0003723=GO_REF:0000037, GO:0051028=GO_REF:0000037, GO:0006917=GO_REF:0000019, GO:0015031=GO_REF:0000037, GO:0003676=GO_REF:0000002, GO:0010043=GO_REF:0000019, GO:0005524=GO_REF:0000037} Q9NUU7 ATP-dependent RNA helicase DDX19A protein 20130413 {GO:0008026=IEA, GO:0031965=IEA, GO:0005737=IEA, GO:0005643=IEA, GO:0003723=IEA, GO:0051028=IEA, GO:0006917=IEA, GO:0015031=IEA, GO:0003676=IEA, GO:0010043=IEA, GO:0005524=IEA} induction of apoptosis, mRNA transport, protein transport, response to zinc ion cytoplasm, nuclear membrane, nuclear pore ATP binding, ATP-dependent helicase activity, RNA binding, nucleic acid binding Human UniProtKB-SubCell:SL-0182 DDX19B LIFEdb UniProtKB {GO:0008026=GO_REF:0000002, GO:0031965=GO_REF:0000039, GO:0005737=GO_REF:0000039, GO:0006406=PMID:10428971, GO:0005643=GO_REF:0000039, GO:0003723=GO_REF:0000037, GO:0004386=PMID:10428971, GO:0005635=GO_REF:0000054, GO:0015031=GO_REF:0000037, GO:0003676=GO_REF:0000002, GO:0005524=GO_REF:0000037} Q9UMR2 ATP-dependent RNA helicase DDX19B protein 20100607 {GO:0008026=IEA, GO:0031965=IEA, GO:0005737=IEA, GO:0006406=TAS, GO:0005643=IEA, GO:0003723=IEA, GO:0004386=TAS, GO:0005635=IDA, GO:0015031=IEA, GO:0003676=IEA, GO:0005524=IEA} mRNA export from nucleus, protein transport cytoplasm, nuclear envelope, nuclear membrane, nuclear pore ATP binding, ATP-dependent helicase activity, RNA binding, helicase activity, nucleic acid binding Human DDX20 HPA UniProtKB {GO:0000244=PMID:10601333, GO:0008026=GO_REF:0000002, GO:0005515=PMID:11714716, GO:0010467=Reactome:REACT_71, GO:0006396=PMID:10601333, GO:0015030=GO_REF:0000039, GO:0043065=GO_REF:0000024, GO:0016070=Reactome:REACT_21257, GO:0005634=GO_REF:0000052, GO:0034660=Reactome:REACT_11052, GO:0000122=GO_REF:0000019, GO:0006917=GO_REF:0000019, GO:0000387=Reactome:REACT_11066, GO:0003676=GO_REF:0000002, GO:0005524=GO_REF:0000037, GO:0003677=GO_REF:0000037, GO:0005829=Reactome:REACT_10041, GO:0004004=PMID:10383418, GO:0005737=GO_REF:0000052, GO:0017053=GO_REF:0000019, GO:0005654=Reactome:REACT_10010, GO:0005681=GO_REF:0000037, GO:0005856=PMID:10383418} Q9UHI6 Probable ATP-dependent RNA helicase DDX20 protein 20080205 {GO:0000244=TAS, GO:0008026=IEA, GO:0005515=IPI, GO:0010467=TAS, GO:0006396=TAS, GO:0015030=IEA, GO:0043065=ISS, GO:0016070=TAS, GO:0005634=IDA, GO:0034660=TAS, GO:0000122=IEA, GO:0006917=IEA, GO:0000387=TAS, GO:0003676=IEA, GO:0005524=IEA, GO:0003677=IEA, GO:0005829=TAS, GO:0004004=TAS, GO:0005737=IDA, GO:0017053=IEA, GO:0005654=TAS, GO:0005681=IEA, GO:0005856=TAS} RNA metabolic process, RNA processing, assembly of spliceosomal tri-snRNP, gene expression, induction of apoptosis, ncRNA metabolic process, negative regulation of transcription from RNA polymerase II promoter, positive regulation of apoptotic process, spliceosomal snRNP assembly Cajal body, cytoplasm, cytoskeleton, cytosol, nucleoplasm, nucleus, spliceosomal complex, transcriptional repressor complex ATP binding, ATP-dependent RNA helicase activity, ATP-dependent helicase activity, DNA binding, nucleic acid binding, protein binding Human DDX21 HPA UniProtKB {GO:0004004=PMID:8614622, GO:0003725=GO_REF:0000019, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0009615=GO_REF:0000019, GO:0043330=GO_REF:0000019, GO:0005524=GO_REF:0000037} Q9NR30 Nucleolar RNA helicase 2 protein 20110516 {GO:0004004=TAS, GO:0003725=IEA, GO:0005730=IDA, GO:0005634=IDA, GO:0009615=IEA, GO:0043330=IEA, GO:0005524=IEA} response to exogenous dsRNA, response to virus nucleolus, nucleus ATP binding, ATP-dependent RNA helicase activity, double-stranded RNA binding Human DDX23 HPA UniProtKB {GO:0008380=Reactome:REACT_1735, GO:0008026=PMID:9539711, GO:0005515=PMID:20858735, GO:0010467=Reactome:REACT_71, GO:0005886=GO_REF:0000052, GO:0004386=GO_REF:0000038, GO:0005730=GO_REF:0000052, GO:0000354=PMID:9539711, GO:0005634=GO_REF:0000052, GO:0003676=GO_REF:0000002, GO:0071013=PMID:11991638, GO:0005524=GO_REF:0000037, GO:0005739=GO_REF:0000052, GO:0004004=PMID:9409622, GO:0000398=Reactome:REACT_1753, GO:0000375=PMID:9409622, GO:0005654=Reactome:REACT_2241, GO:0005682=PMID:9539711} Q9BUQ8 Probable ATP-dependent RNA helicase DDX23 protein 20110516 {GO:0008380=TAS, GO:0008026=IDA, GO:0005515=IPI, GO:0010467=TAS, GO:0005886=IDA, GO:0004386=IEA, GO:0005730=IDA, GO:0000354=IC, GO:0005634=IDA, GO:0003676=IEA, GO:0071013=IDA, GO:0005524=IEA, GO:0005739=IDA, GO:0004004=TAS, GO:0000398=TAS, GO:0000375=TAS, GO:0005654=TAS, GO:0005682=IDA} RNA splicing, RNA splicing, via transesterification reactions, cis assembly of pre-catalytic spliceosome, gene expression, mRNA splicing, via spliceosome U5 snRNP, catalytic step 2 spliceosome, mitochondrion, nucleolus, nucleoplasm, nucleus, plasma membrane ATP binding, ATP-dependent RNA helicase activity, ATP-dependent helicase activity, helicase activity, nucleic acid binding, protein binding Human DDX24 HPA UniProtKB {GO:0004004=GO_REF:0000029, GO:0008026=GO_REF:0000002, GO:0003724=PMID:10936056, GO:0005737=GO_REF:0000052, GO:0016070=PMID:10936056, GO:0003723=GO_REF:0000037, GO:0005730=GO_REF:0000052, GO:0003676=GO_REF:0000002, GO:0005524=GO_REF:0000037} Q9GZR7 ATP-dependent RNA helicase DDX24 protein 20080205 {GO:0004004=NAS, GO:0008026=IEA, GO:0003724=NAS, GO:0005737=IDA, GO:0016070=NAS, GO:0003723=IEA, GO:0005730=IDA, GO:0003676=IEA, GO:0005524=IEA} RNA metabolic process cytoplasm, nucleolus ATP binding, ATP-dependent RNA helicase activity, ATP-dependent helicase activity, RNA binding, RNA helicase activity, nucleic acid binding Human DDX26B null null {} null null null null {} null null null DDX27 UniProtKB UniProtKB {GO:0008026=GO_REF:0000002, GO:0005634=GO_REF:0000039, GO:0003676=GO_REF:0000002, GO:0005524=GO_REF:0000037} Q96GQ7 Probable ATP-dependent RNA helicase DDX27 protein 20130413 {GO:0008026=IEA, GO:0005634=IEA, GO:0003676=IEA, GO:0005524=IEA} nucleus ATP binding, ATP-dependent helicase activity, nucleic acid binding Human UniProtKB-SubCell:SL-0191 DDX28 HPA UniProtKB {GO:0042645=PMID:18063578, GO:0005739=GO_REF:0000052, GO:0008026=GO_REF:0000002, GO:0005737=GO_REF:0000052, GO:0003723=GO_REF:0000037, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0005524=GO_REF:0000037} Q9NUL7 Probable ATP-dependent RNA helicase DDX28 protein 20111111 {GO:0042645=IDA, GO:0005739=IDA, GO:0008026=IEA, GO:0005737=IDA, GO:0003723=IEA, GO:0005730=IDA, GO:0005634=IDA, GO:0005524=IEA} cytoplasm, mitochondrial nucleoid, mitochondrion, nucleolus, nucleus ATP binding, ATP-dependent helicase activity, RNA binding Human DDX31 UniProtKB UniProtKB {GO:0008026=GO_REF:0000002, GO:0003723=GO_REF:0000037, GO:0005730=GO_REF:0000039, GO:0004386=GO_REF:0000038, GO:0005524=GO_REF:0000037} Q9H8H2 Probable ATP-dependent RNA helicase DDX31 protein 20130413 {GO:0008026=IEA, GO:0003723=IEA, GO:0005730=IEA, GO:0004386=IEA, GO:0005524=IEA} nucleolus ATP binding, ATP-dependent helicase activity, RNA binding, helicase activity Human UniProtKB-SubCell:SL-0188 DDX39A InterPro UniProtKB {GO:0005515=PMID:21859714, GO:0008026=GO_REF:0000002, GO:0005737=PMID:21859714, GO:0006406=PMID:15047853, GO:0000398=PMID:15047853, GO:0005634=PMID:21859714, GO:0003676=GO_REF:0000002, GO:0005524=GO_REF:0000002} Q8N5M0 DEAD (Asp-Glu-Ala-Asp) box polypeptide 39, isoform CRA_c protein 20130413 {GO:0005515=IPI, GO:0008026=IEA, GO:0005737=IDA, GO:0006406=IGI, GO:0000398=IGI, GO:0005634=IDA, GO:0003676=IEA, GO:0005524=IEA} mRNA export from nucleus, mRNA splicing, via spliceosome cytoplasm, nucleus ATP binding, ATP-dependent helicase activity, nucleic acid binding, protein binding Human InterPro:IPR011545 DDX39B UniProtKB UniProtKB {GO:0008380=PMID:18593880, GO:0008026=GO_REF:0000002, GO:0005515=PMID:21859714, GO:0000245=PMID:18593880, GO:0043008=PMID:18593880, GO:0000346=PMID:15998806, GO:0004386=GO_REF:0000002, GO:0030621=PMID:18593880, GO:0005634=PMID:21859714, GO:0003676=GO_REF:0000002, GO:0005524=GO_REF:0000038, GO:0046784=PMID:18974867, GO:0008186=PMID:17562711, GO:0004004=PMID:18593880, GO:0005737=PMID:21859714, GO:0006406=PMID:17190602, GO:0016607=GO_REF:0000039, GO:0000398=PMID:15047853, GO:0010501=PMID:18593880, GO:0005681=PMID:18593880, GO:0017070=PMID:18593880, GO:0005687=PMID:18593880, GO:0005688=PMID:18593880} Q5STU3 Spliceosome RNA helicase DDX39B protein 20130413 {GO:0008380=IDA, GO:0008026=IEA, GO:0005515=IPI, GO:0000245=IDA, GO:0043008=IDA, GO:0000346=IDA, GO:0004386=IEA, GO:0030621=IDA, GO:0005634=IDA, GO:0003676=IEA, GO:0005524=IEA, GO:0046784=IDA, GO:0008186=IDA, GO:0004004=IDA, GO:0005737=IDA, GO:0006406=IDA, GO:0016607=IEA, GO:0000398=IGI, GO:0010501=IDA, GO:0005681=IDA, GO:0017070=IDA, GO:0005687=IDA, GO:0005688=IDA} RNA secondary structure unwinding, RNA splicing, intronless viral mRNA export from host nucleus, mRNA export from nucleus, mRNA splicing, via spliceosome, spliceosomal complex assembly U4 snRNP, U6 snRNP, cytoplasm, nuclear speck, nucleus, spliceosomal complex, transcription export complex ATP binding, ATP-dependent RNA helicase activity, ATP-dependent helicase activity, ATP-dependent protein binding, RNA-dependent ATPase activity, U4 snRNA binding, U6 snRNA binding, helicase activity, nucleic acid binding, protein binding Human UniProtKB-KW:KW-0067 DDX3X GOC UniProtKB {GO:0005515=PMID:22323517, GO:0017148=PMID:17667941, GO:0048027=PMID:22872150, GO:0030308=PMID:16818630, GO:0030307=PMID:20837705, GO:0007243=PMID:18636090, GO:0043024=PMID:22323517, GO:0032728=PMID:18583960, GO:0005852=PMID:18628297, GO:0042256=PMID:22323517, GO:0071470=PMID:21883093, GO:2001243=PMID:21883093, GO:0043280=PMID:16301996, GO:0034063=PMID:21883093, GO:0010501=PMID:22872150, GO:0045087=PMID:18583960, GO:0071243=PMID:21883093, GO:0008134=PMID:16818630, GO:0008625=PMID:18846110, GO:0035613=PMID:22872150, GO:0006200=PMID:21589879, GO:1900087=PMID:20837705, GO:0010494=PMID:21883093, GO:0003723=PMID:21589879, GO:0071651=PMID:18583960, GO:0005741=GO_REF:0000039, GO:0005634=PMID:10329544, GO:0004004=PMID:21589879, GO:0005737=GO_REF:0000052, GO:0004003=PMID:21589879, GO:0007059=PMID:21730191, GO:0031333=PMID:17667941, GO:0045944=PMID:18583960, GO:0008143=PMID:18596238, GO:0045948=PMID:20837705, GO:0043154=PMID:18846110, GO:0016887=PMID:21589879, GO:0043066=PMID:18846110, GO:0043065=PMID:16301996, GO:0004386=GO_REF:0000038, GO:0045727=PMID:18596238, GO:0009615=PMID:18636090, GO:0005524=GO_REF:0000037, GO:0003677=PMID:21589879, GO:0097193=PMID:16301996, GO:0006351=GO_REF:0000037, GO:0016607=GO_REF:0000039, GO:0022627=PMID:18596238, GO:0019048=GO_REF:0000037, GO:0008190=PMID:17667941, GO:0031369=PMID:22323517} O00571 ATP-dependent RNA helicase DDX3X protein 20130413 {GO:0005515=IPI, GO:0017148=IMP, GO:0048027=IDA, GO:0030308=IDA, GO:0030307=IMP, GO:0007243=IDA, GO:0043024=IDA, GO:0032728=TAS, GO:0005852=IDA, GO:0042256=IMP, GO:0071470=IDA, GO:2001243=IMP, GO:0043280=IMP, GO:0034063=IDA, GO:0010501=IDA, GO:0045087=IMP, GO:0071243=IDA, GO:0008134=IDA, GO:0008625=IMP, GO:0035613=IDA, GO:0006200=IDA, GO:1900087=IMP, GO:0010494=IDA, GO:0003723=IDA, GO:0071651=TAS, GO:0005741=IEA, GO:0005634=IDA, GO:0004004=IDA, GO:0005737=IDA, GO:0004003=IDA, GO:0007059=IMP, GO:0031333=IDA, GO:0045944=IMP, GO:0008143=IDA, GO:0045948=IMP, GO:0043154=IMP, GO:0016887=IDA, GO:0043066=IMP, GO:0043065=IMP, GO:0004386=IEA, GO:0045727=IDA, GO:0009615=IDA, GO:0005524=IEA, GO:0003677=IDA, GO:0097193=IMP, GO:0006351=IEA, GO:0016607=IEA, GO:0022627=IDA, GO:0019048=IEA, GO:0008190=IDA, GO:0031369=IDA} ATP catabolic process, RNA secondary structure unwinding, cellular response to arsenic-containing substance, cellular response to osmotic stress, chromosome segregation, extrinsic apoptotic signaling pathway via death domain receptors, innate immune response, intracellular protein kinase cascade, intrinsic apoptotic signaling pathway, mature ribosome assembly, negative regulation of apoptotic process, negative regulation of cell growth, negative regulation of cysteine-type endopeptidase activity involved in apoptotic process, negative regulation of intrinsic apoptotic signaling pathway, negative regulation of protein complex assembly, negative regulation of translation, positive regulation of G1/S transition of mitotic cell cycle, positive regulation of apoptotic process, positive regulation of cell growth, positive regulation of chemokine (C-C motif) ligand 5 production, positive regulation of cysteine-type endopeptidase activity involved in apoptotic process, positive regulation of interferon-beta production, positive regulation of transcription from RNA polymerase II promoter, positive regulation of translation, positive regulation of translational initiation, response to virus, stress granule assembly, transcription, DNA-dependent, virus-host interaction cytoplasm, cytoplasmic stress granule, cytosolic small ribosomal subunit, eukaryotic translation initiation factor 3 complex, mitochondrial outer membrane, nuclear speck, nucleus ATP binding, ATP-dependent DNA helicase activity, ATP-dependent RNA helicase activity, ATPase activity, DNA binding, RNA binding, RNA stem-loop binding, eukaryotic initiation factor 4E binding, helicase activity, mRNA 5'-UTR binding, poly(A) RNA binding, protein binding, ribosomal small subunit binding, transcription factor binding, translation initiation factor binding Human DDX3Y HPA UniProtKB {GO:0008026=GO_REF:0000002, GO:0005737=GO_REF:0000052, GO:0003723=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0003676=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0005524=GO_REF:0000037} O15523 ATP-dependent RNA helicase DDX3Y protein 20101115 {GO:0008026=IEA, GO:0005737=IDA, GO:0003723=IEA, GO:0005634=IEA, GO:0003676=IEA, GO:0003677=IEA, GO:0005524=IEA} cytoplasm, nucleus ATP binding, ATP-dependent helicase activity, DNA binding, RNA binding, nucleic acid binding Human DDX4 UniProtKB UniProtKB {GO:0008026=GO_REF:0000002, GO:0048471=GO_REF:0000039, GO:0000237=GO_REF:0000019, GO:0005634=GO_REF:0000019, GO:0007275=GO_REF:0000037, GO:0030317=PMID:21034600, GO:0007283=GO_REF:0000019, GO:0003676=GO_REF:0000002, GO:0005524=GO_REF:0000037, GO:0032880=GO_REF:0000019, GO:0033391=GO_REF:0000019, GO:0005737=PMID:21421998, GO:0071546=GO_REF:0000024, GO:0071547=GO_REF:0000024, GO:0007141=GO_REF:0000019} Q9NQI0 Probable ATP-dependent RNA helicase DDX4 protein 20110412 {GO:0008026=IEA, GO:0048471=IEA, GO:0000237=IEA, GO:0005634=IEA, GO:0007275=IEA, GO:0030317=IMP, GO:0007283=IEA, GO:0003676=IEA, GO:0005524=IEA, GO:0032880=IEA, GO:0033391=IEA, GO:0005737=IDA, GO:0071546=ISS, GO:0071547=ISS, GO:0007141=IEA} leptotene, male meiosis I, multicellular organismal development, regulation of protein localization, sperm motility, spermatogenesis chromatoid body, cytoplasm, nucleus, perinuclear region of cytoplasm, pi-body, piP-body ATP binding, ATP-dependent helicase activity, nucleic acid binding Human DDX41 HPA UniProtKB {GO:0008026=GO_REF:0000002, GO:0006396=PMID:10607561, GO:0035458=GO_REF:0000019, GO:0005783=GO_REF:0000019, GO:0003723=GO_REF:0000037, GO:0005730=GO_REF:0000052, GO:0006915=PMID:10607561, GO:0007275=PMID:10607561, GO:0005634=GO_REF:0000052, GO:0071013=PMID:11991638, GO:0003676=GO_REF:0000002, GO:0005524=GO_REF:0000037, GO:0003677=GO_REF:0000019, GO:0051607=GO_REF:0000019, GO:0000398=PMID:11991638, GO:0045944=GO_REF:0000019, GO:0008270=GO_REF:0000002} Q9UJV9 Probable ATP-dependent RNA helicase DDX41 protein 20101115 {GO:0008026=IEA, GO:0006396=TAS, GO:0035458=IEA, GO:0005783=IEA, GO:0003723=IEA, GO:0005730=IDA, GO:0006915=TAS, GO:0007275=TAS, GO:0005634=IDA, GO:0071013=IDA, GO:0003676=IEA, GO:0005524=IEA, GO:0003677=IEA, GO:0051607=IEA, GO:0000398=IC, GO:0045944=IEA, GO:0008270=IEA} RNA processing, apoptotic process, cellular response to interferon-beta, defense response to virus, mRNA splicing, via spliceosome, multicellular organismal development, positive regulation of transcription from RNA polymerase II promoter catalytic step 2 spliceosome, endoplasmic reticulum, nucleolus, nucleus ATP binding, ATP-dependent helicase activity, DNA binding, RNA binding, nucleic acid binding, zinc ion binding NOT Human DDX42 HPA UniProtKB {GO:0005515=PMID:19377511, GO:0008026=GO_REF:0000002, GO:0005737=GO_REF:0000052, GO:0008104=PMID:19377511, GO:0015030=GO_REF:0000039, GO:0016607=GO_REF:0000039, GO:0003723=GO_REF:0000037, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0005524=GO_REF:0000037} Q86XP3 ATP-dependent RNA helicase DDX42 protein 20101115 {GO:0005515=IPI, GO:0008026=IEA, GO:0005737=IDA, GO:0008104=IDA, GO:0015030=IEA, GO:0016607=IEA, GO:0003723=IEA, GO:0005730=IDA, GO:0005634=IDA, GO:0005524=IEA} protein localization Cajal body, cytoplasm, nuclear speck, nucleolus, nucleus ATP binding, ATP-dependent helicase activity, RNA binding, protein binding Human DDX43 LIFEdb UniProtKB {GO:0005622=GO_REF:0000054, GO:0004004=PMID:10919659, GO:0003723=GO_REF:0000037, GO:0004386=GO_REF:0000038, GO:0005524=GO_REF:0000037} Q9NXZ2 Probable ATP-dependent RNA helicase DDX43 protein 20100607 {GO:0005622=IDA, GO:0004004=TAS, GO:0003723=IEA, GO:0004386=IEA, GO:0005524=IEA} intracellular ATP binding, ATP-dependent RNA helicase activity, RNA binding, helicase activity Human DDX46 HPA UniProtKB {GO:0008380=GO_REF:0000037, GO:0006397=GO_REF:0000037, GO:0008026=GO_REF:0000002, GO:0015030=GO_REF:0000039, GO:0016607=GO_REF:0000039, GO:0003723=GO_REF:0000037, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0003676=GO_REF:0000002, GO:0005524=GO_REF:0000037} Q7L014 Probable ATP-dependent RNA helicase DDX46 protein 20110516 {GO:0008380=IEA, GO:0006397=IEA, GO:0008026=IEA, GO:0015030=IEA, GO:0016607=IEA, GO:0003723=IEA, GO:0005730=IDA, GO:0005634=IDA, GO:0003676=IEA, GO:0005524=IEA} RNA splicing, mRNA processing Cajal body, nuclear speck, nucleolus, nucleus ATP binding, ATP-dependent helicase activity, RNA binding, nucleic acid binding Human DDX47 HPA UniProtKB {GO:0008380=PMID:16963496, GO:0005515=PMID:15977068, GO:0006397=GO_REF:0000037, GO:0008026=GO_REF:0000002, GO:0006364=PMID:16963496, GO:0003723=GO_REF:0000037, GO:0005730=GO_REF:0000052, GO:0006915=PMID:15977068, GO:0003676=GO_REF:0000002, GO:0005524=GO_REF:0000037} Q9H0S4 Probable ATP-dependent RNA helicase DDX47 protein 20090616 {GO:0008380=IMP, GO:0005515=IPI, GO:0006397=IEA, GO:0008026=IEA, GO:0006364=IMP, GO:0003723=IEA, GO:0005730=IDA, GO:0006915=IDA, GO:0003676=IEA, GO:0005524=IEA} RNA splicing, apoptotic process, mRNA processing, rRNA processing nucleolus ATP binding, ATP-dependent helicase activity, RNA binding, nucleic acid binding, protein binding Human DDX49 UniProtKB UniProtKB {GO:0008026=GO_REF:0000002, GO:0003723=GO_REF:0000037, GO:0003676=GO_REF:0000002, GO:0005524=GO_REF:0000037} Q9Y6V7 Probable ATP-dependent RNA helicase DDX49 protein 20130413 {GO:0008026=IEA, GO:0003723=IEA, GO:0003676=IEA, GO:0005524=IEA} ATP binding, ATP-dependent helicase activity, RNA binding, nucleic acid binding Human UniProtKB-KW:KW-0067 DDX5 HPA UniProtKB {GO:0005515=PMID:22266867, GO:0005516=GO_REF:0000019, GO:0003724=PMID:21343338, GO:0045069=GO_REF:0000019, GO:0005634=GO_REF:0000052, GO:0050681=PMID:18829551, GO:0071013=PMID:11991638, GO:0004004=GO_REF:0000019, GO:0000381=PMID:21343338, GO:0045944=PMID:10409727, GO:2001014=GO_REF:0000024, GO:0036002=PMID:21343338, GO:0003712=GO_REF:0000019, GO:0008026=GO_REF:0000002, GO:0030331=PMID:10409727, GO:0003713=PMID:10409727, GO:0060765=PMID:18829551, GO:0005730=GO_REF:0000052, GO:0000122=PMID:15298701, GO:0003676=GO_REF:0000002, GO:0001701=GO_REF:0000019, GO:0005524=GO_REF:0000037, GO:0006351=GO_REF:0000037, GO:0045667=GO_REF:0000024, GO:0072332=PMID:15660129, GO:0000398=PMID:11991638, GO:0030529=PMID:18809582, GO:0043517=PMID:15660129, GO:0007623=GO_REF:0000019, GO:0016049=PMID:2451786, GO:0033148=PMID:11250900, GO:0045893=GO_REF:0000019, GO:0019899=GO_REF:0000019, GO:0048306=GO_REF:0000019} P17844 Probable ATP-dependent RNA helicase DDX5 protein 20101115 {GO:0005515=IPI, GO:0005516=IEA, GO:0003724=IMP, GO:0045069=IEA, GO:0005634=IDA, GO:0050681=IDA, GO:0071013=IDA, GO:0004004=IEA, GO:0000381=IDA, GO:0045944=IDA, GO:2001014=ISS, GO:0036002=IDA, GO:0003712=IEA, GO:0008026=IEA, GO:0030331=IDA, GO:0003713=IDA, GO:0060765=IMP, GO:0005730=IDA, GO:0000122=IDA, GO:0003676=IEA, GO:0001701=IEA, GO:0005524=IEA, GO:0006351=IEA, GO:0045667=ISS, GO:0072332=IMP, GO:0000398=IC, GO:0030529=IDA, GO:0043517=IMP, GO:0007623=IEA, GO:0016049=NAS, GO:0033148=IDA, GO:0045893=IEA, GO:0019899=IEA, GO:0048306=IEA} cell growth, circadian rhythm, in utero embryonic development, intrinsic apoptotic signaling pathway by p53 class mediator, mRNA splicing, via spliceosome, negative regulation of transcription from RNA polymerase II promoter, positive regulation of DNA damage response, signal transduction by p53 class mediator, positive regulation of intracellular estrogen receptor signaling pathway, positive regulation of transcription from RNA polymerase II promoter, positive regulation of transcription, DNA-dependent, regulation of alternative mRNA splicing, via spliceosome, regulation of androgen receptor signaling pathway, regulation of osteoblast differentiation, regulation of skeletal muscle cell differentiation, regulation of viral genome replication, transcription, DNA-dependent catalytic step 2 spliceosome, nucleolus, nucleus, ribonucleoprotein complex ATP binding, ATP-dependent RNA helicase activity, ATP-dependent helicase activity, RNA helicase activity, androgen receptor binding, calcium-dependent protein binding, calmodulin binding, enzyme binding, estrogen receptor binding, nucleic acid binding, pre-mRNA binding, protein binding, transcription coactivator activity, transcription cofactor activity NOT Human DDX50 HPA UniProtKB {GO:0008026=GO_REF:0000002, GO:0005886=GO_REF:0000052, GO:0003723=GO_REF:0000037, GO:0005730=GO_REF:0000052, GO:0005524=GO_REF:0000037} Q9BQ39 ATP-dependent RNA helicase DDX50 protein 20110516 {GO:0008026=IEA, GO:0005886=IDA, GO:0003723=IEA, GO:0005730=IDA, GO:0005524=IEA} nucleolus, plasma membrane ATP binding, ATP-dependent helicase activity, RNA binding Human DDX51 UniProtKB UniProtKB {GO:0008026=GO_REF:0000002, GO:0006364=GO_REF:0000037, GO:0003723=GO_REF:0000037, GO:0005730=GO_REF:0000039, GO:0005524=GO_REF:0000037} Q8N8A6 ATP-dependent RNA helicase DDX51 protein 20130413 {GO:0008026=IEA, GO:0006364=IEA, GO:0003723=IEA, GO:0005730=IEA, GO:0005524=IEA} rRNA processing nucleolus ATP binding, ATP-dependent helicase activity, RNA binding Human UniProtKB-SubCell:SL-0188 DDX52 UniProtKB UniProtKB {GO:0008026=GO_REF:0000002, GO:0003723=GO_REF:0000037, GO:0005730=GO_REF:0000039, GO:0004386=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0005524=GO_REF:0000037} Q9Y2R4 Probable ATP-dependent RNA helicase DDX52 protein 20130413 {GO:0008026=IEA, GO:0003723=IEA, GO:0005730=IEA, GO:0004386=IEA, GO:0003676=IEA, GO:0005524=IEA} nucleolus ATP binding, ATP-dependent helicase activity, RNA binding, helicase activity, nucleic acid binding Human UniProtKB-SubCell:SL-0188 DDX53 UniProtKB UniProtKB {GO:0008026=GO_REF:0000002, GO:0003723=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0005524=GO_REF:0000037} Q86TM3 Probable ATP-dependent RNA helicase DDX53 protein 20130413 {GO:0008026=IEA, GO:0003723=IEA, GO:0005634=IEA, GO:0005524=IEA} nucleus ATP binding, ATP-dependent helicase activity, RNA binding Human UniProtKB-SubCell:SL-0191 DDX54 UniProtKB UniProtKB {GO:0008026=GO_REF:0000002, GO:0006396=PMID:12466272, GO:0006355=GO_REF:0000037, GO:0016070=PMID:12466272, GO:0003723=GO_REF:0000037, GO:0003714=PMID:12466272, GO:0030331=PMID:12466272, GO:0005102=PMID:12466272, GO:0005730=PMID:12466272, GO:0005634=PMID:12466272, GO:0003676=GO_REF:0000002, GO:0016818=GO_REF:0000002, GO:0005524=GO_REF:0000037, GO:0006351=GO_REF:0000037, GO:0004004=PMID:12466272, GO:0030520=PMID:12466272} Q8TDD1 ATP-dependent RNA helicase DDX54 protein 20041203 {GO:0008026=IEA, GO:0006396=IDA, GO:0006355=IEA, GO:0016070=IDA, GO:0003723=IEA, GO:0003714=IDA, GO:0030331=IDA, GO:0005102=IDA, GO:0005730=IDA, GO:0005634=IDA, GO:0003676=IEA, GO:0016818=IEA, GO:0005524=IEA, GO:0006351=IEA, GO:0004004=IDA, GO:0030520=TAS} RNA metabolic process, RNA processing, intracellular estrogen receptor signaling pathway, regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleolus, nucleus ATP binding, ATP-dependent RNA helicase activity, ATP-dependent helicase activity, RNA binding, estrogen receptor binding, hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides, nucleic acid binding, receptor binding, transcription corepressor activity Human DDX55 UniProtKB UniProtKB {GO:0008026=GO_REF:0000002, GO:0003723=GO_REF:0000037, GO:0003676=GO_REF:0000002, GO:0005524=GO_REF:0000037} Q8NHQ9 ATP-dependent RNA helicase DDX55 protein 20130413 {GO:0008026=IEA, GO:0003723=IEA, GO:0003676=IEA, GO:0005524=IEA} ATP binding, ATP-dependent helicase activity, RNA binding, nucleic acid binding Human UniProtKB-KW:KW-0067 DDX56 LIFEdb UniProtKB {GO:0004004=PMID:10749921, GO:0008026=GO_REF:0000002, GO:0006364=GO_REF:0000037, GO:0003723=GO_REF:0000037, GO:0005730=GO_REF:0000054, GO:0003676=GO_REF:0000002, GO:0005524=GO_REF:0000037} Q9NY93 Probable ATP-dependent RNA helicase DDX56 protein 20100607 {GO:0004004=TAS, GO:0008026=IEA, GO:0006364=IEA, GO:0003723=IEA, GO:0005730=IDA, GO:0003676=IEA, GO:0005524=IEA} rRNA processing nucleolus ATP binding, ATP-dependent RNA helicase activity, ATP-dependent helicase activity, RNA binding, nucleic acid binding Human DDX58 BHF-UCL UniProtKB {GO:0005515=PMID:17079289, GO:0003725=PMID:17079289, GO:0003727=PMID:19211564, GO:0015629=PMID:19122199, GO:0042993=PMID:17079289, GO:0042802=PMID:21102435, GO:0005829=Reactome:REACT_25398, GO:0051091=PMID:17079289, GO:0005737=PMID:21102435, GO:0003690=GO_REF:0000019, GO:0045944=PMID:17079289, GO:0009597=PMID:17079289, GO:0032480=Reactome:REACT_25271, GO:0008026=GO_REF:0000002, GO:0030334=PMID:19122199, GO:0032728=PMID:17079289, GO:0034344=PMID:21616437, GO:0032727=PMID:19576794, GO:0032587=PMID:19122199, GO:0003676=GO_REF:0000002, GO:0009615=PMID:21616437, GO:0005524=GO_REF:0000037, GO:0039529=PMID:19211564, GO:0039528=PMID:21616437, GO:0045087=Reactome:REACT_6802, GO:0019048=GO_REF:0000037, GO:0002230=PMID:19609254, GO:0008270=PMID:18243112, GO:0005923=PMID:19122199, GO:0043330=GO_REF:0000019} O95786 Probable ATP-dependent RNA helicase DDX58 protein 20110418 {GO:0005515=IPI, GO:0003725=TAS, GO:0003727=IMP, GO:0015629=IDA, GO:0042993=IDA, GO:0042802=IPI, GO:0005829=TAS, GO:0051091=IC, GO:0005737=IDA, GO:0003690=IEA, GO:0045944=IDA, GO:0009597=IDA, GO:0032480=TAS, GO:0008026=IEA, GO:0030334=IDA, GO:0032728=IDA, GO:0034344=TAS, GO:0032727=IDA, GO:0032587=IDA, GO:0003676=IEA, GO:0009615=TAS, GO:0005524=IEA, GO:0039529=IMP, GO:0039528=TAS, GO:0045087=TAS, GO:0019048=IEA, GO:0002230=IMP, GO:0008270=IDA, GO:0005923=IDA, GO:0043330=IEA} RIG-I signaling pathway, cytoplasmic pattern recognition receptor signaling pathway in response to virus, detection of virus, innate immune response, negative regulation of type I interferon production, positive regulation of defense response to virus by host, positive regulation of interferon-alpha production, positive regulation of interferon-beta production, positive regulation of sequence-specific DNA binding transcription factor activity, positive regulation of transcription factor import into nucleus, positive regulation of transcription from RNA polymerase II promoter, regulation of cell migration, regulation of type III interferon production, response to exogenous dsRNA, response to virus, virus-host interaction actin cytoskeleton, cytoplasm, cytosol, ruffle membrane, tight junction ATP binding, ATP-dependent helicase activity, double-stranded DNA binding, double-stranded RNA binding, identical protein binding, nucleic acid binding, protein binding, single-stranded RNA binding, zinc ion binding Human DDX6 IntAct UniProtKB {GO:0008026=GO_REF:0000002, GO:0005515=PMID:16364915, GO:0003724=PMID:1579499, GO:0010467=Reactome:REACT_71, GO:0033962=PMID:20826699, GO:0016070=Reactome:REACT_21257, GO:0016071=Reactome:REACT_20605, GO:0010494=PMID:17392519, GO:0003723=GO_REF:0000037, GO:0004386=PMID:1579499, GO:0043928=Reactome:REACT_20518, GO:0005524=GO_REF:0000037, GO:0016442=PMID:20616046, GO:0005829=Reactome:REACT_20560, GO:0000932=PMID:20826699, GO:0000288=Reactome:REACT_20639} P26196 Probable ATP-dependent RNA helicase DDX6 protein 20130415 {GO:0008026=IEA, GO:0005515=IPI, GO:0003724=TAS, GO:0010467=TAS, GO:0033962=IDA, GO:0016070=TAS, GO:0016071=TAS, GO:0010494=IDA, GO:0003723=IEA, GO:0004386=TAS, GO:0043928=TAS, GO:0005524=IEA, GO:0016442=IDA, GO:0005829=TAS, GO:0000932=IDA, GO:0000288=TAS} RNA metabolic process, cytoplasmic mRNA processing body assembly, exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay, gene expression, mRNA metabolic process, nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay RNA-induced silencing complex, cytoplasmic mRNA processing body, cytoplasmic stress granule, cytosol ATP binding, ATP-dependent helicase activity, RNA binding, RNA helicase activity, helicase activity, protein binding Human UniProtKB:Q9NPI6 DDX60 UniProtKB UniProtKB {GO:0008026=GO_REF:0000002, GO:0003725=PMID:21791617, GO:0005515=PMID:21791617, GO:0003727=PMID:21791617, GO:0003723=GO_REF:0000019, GO:1900246=PMID:21791617, GO:1900245=PMID:21791617, GO:0009615=PMID:21791617, GO:0005524=GO_REF:0000037, GO:0005737=PMID:21791617, GO:0051607=GO_REF:0000019, GO:0003690=PMID:21791617, GO:0045087=GO_REF:0000037} Q8IY21 Probable ATP-dependent RNA helicase DDX60 protein 20120402 {GO:0008026=IEA, GO:0003725=IDA, GO:0005515=IPI, GO:0003727=IDA, GO:0003723=IEA, GO:1900246=IMP, GO:1900245=IMP, GO:0009615=IDA, GO:0005524=IEA, GO:0005737=IDA, GO:0051607=IEA, GO:0003690=IDA, GO:0045087=IEA} defense response to virus, innate immune response, positive regulation of MDA-5 signaling pathway, positive regulation of RIG-I signaling pathway, response to virus cytoplasm ATP binding, ATP-dependent helicase activity, RNA binding, double-stranded DNA binding, double-stranded RNA binding, protein binding, single-stranded RNA binding Human UniProtKB:Q9Y3B2 DDX60L UniProtKB UniProtKB {GO:0008026=GO_REF:0000002, GO:0003723=GO_REF:0000037, GO:0003676=GO_REF:0000002, GO:0005524=GO_REF:0000037} Q5H9U9 Probable ATP-dependent RNA helicase DDX60-like protein 20130413 {GO:0008026=IEA, GO:0003723=IEA, GO:0003676=IEA, GO:0005524=IEA} ATP binding, ATP-dependent helicase activity, RNA binding, nucleic acid binding Human UniProtKB-KW:KW-0067 DEAF1 IntAct UniProtKB {GO:0005515=PMID:21988832, GO:0005667=GO_REF:0000019, GO:0006357=GO_REF:0000019, GO:0006366=GO_REF:0000019, GO:0048706=GO_REF:0000024, GO:0001843=GO_REF:0000024, GO:0005576=GO_REF:0000039, GO:0003677=GO_REF:0000037, GO:0007281=PMID:9773984, GO:0009653=PMID:9773984, GO:0033599=PMID:18826651, GO:0005737=GO_REF:0000039, GO:0008270=GO_REF:0000002} O75398 Deformed epidermal autoregulatory factor 1 homolog protein 20130415 {GO:0005515=IPI, GO:0005667=IEA, GO:0006357=IEA, GO:0006366=IEA, GO:0048706=ISS, GO:0001843=ISS, GO:0005576=IEA, GO:0003677=IEA, GO:0007281=TAS, GO:0009653=TAS, GO:0033599=IDA, GO:0005737=IEA, GO:0008270=IEA} anatomical structure morphogenesis, embryonic skeletal system development, germ cell development, neural tube closure, regulation of mammary gland epithelial cell proliferation, regulation of transcription from RNA polymerase II promoter, transcription from RNA polymerase II promoter cytoplasm, extracellular region, transcription factor complex DNA binding, protein binding, zinc ion binding Human UniProtKB:P42771 DEC1 PINC UniProtKB {GO:0008285=PMID:10612805} Q9P2X7 Deleted in esophageal cancer 1 protein 20030904 {GO:0008285=TAS} negative regulation of cell proliferation Human DECR1 HPA UniProtKB {GO:0008670=PMID:15531764, GO:0006635=Reactome:REACT_1473, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0044281=Reactome:REACT_111217, GO:0070402=PMID:15531764, GO:0005739=GO_REF:0000052, GO:0005737=GO_REF:0000052, GO:0051289=PMID:15531764, GO:0005759=Reactome:REACT_164, GO:0016651=Reactome:REACT_164, GO:0016491=GO_REF:0000002, GO:0044255=Reactome:REACT_22279} Q16698 2,4-dienoyl-CoA reductase, mitochondrial protein 20110516 {GO:0008670=IDA, GO:0006635=TAS, GO:0005730=IDA, GO:0005634=IDA, GO:0044281=TAS, GO:0070402=IDA, GO:0005739=IDA, GO:0005737=IDA, GO:0051289=IDA, GO:0005759=TAS, GO:0016651=TAS, GO:0016491=IEA, GO:0044255=TAS} cellular lipid metabolic process, fatty acid beta-oxidation, protein homotetramerization, small molecule metabolic process cytoplasm, mitochondrial matrix, mitochondrion, nucleolus, nucleus 2,4-dienoyl-CoA reductase (NADPH) activity, NADPH binding, oxidoreductase activity, oxidoreductase activity, acting on NAD(P)H Human DECR2 UniProtKB UniProtKB {GO:0008670=PMID:11514237, GO:0006636=PMID:11514237, GO:0019166=PMID:10811639, GO:0005102=PMID:20178365, GO:0016491=GO_REF:0000002, GO:0005778=GO_REF:0000019} Q9NUI1 Peroxisomal 2,4-dienoyl-CoA reductase protein 20120427 {GO:0008670=IDA, GO:0006636=IDA, GO:0019166=IDA, GO:0005102=IPI, GO:0016491=IEA, GO:0005778=IEA} unsaturated fatty acid biosynthetic process peroxisomal membrane 2,4-dienoyl-CoA reductase (NADPH) activity, oxidoreductase activity, receptor binding, trans-2-enoyl-CoA reductase (NADPH) activity Human UniProtKB:P50542 DEDD IntAct UniProtKB {GO:0008625=PMID:9774341, GO:0005515=PMID:20195357, GO:0046697=GO_REF:0000019, GO:0005737=GO_REF:0000024, GO:0042177=GO_REF:0000019, GO:0005730=GO_REF:0000024, GO:0042981=GO_REF:0000002, GO:0006917=GO_REF:0000024, GO:0007283=GO_REF:0000019, GO:0045892=GO_REF:0000024, GO:0003677=GO_REF:0000024, GO:0006351=GO_REF:0000037} O75618 Death effector domain-containing protein protein 20130415 {GO:0008625=TAS, GO:0005515=IPI, GO:0046697=IEA, GO:0005737=ISS, GO:0042177=IEA, GO:0005730=ISS, GO:0042981=IEA, GO:0006917=ISS, GO:0007283=IEA, GO:0045892=ISS, GO:0003677=ISS, GO:0006351=IEA} decidualization, extrinsic apoptotic signaling pathway via death domain receptors, induction of apoptosis, negative regulation of protein catabolic process, negative regulation of transcription, DNA-dependent, regulation of apoptotic process, spermatogenesis, transcription, DNA-dependent cytoplasm, nucleolus DNA binding, protein binding Human UniProtKB:Q06481 DEDD2 HPA UniProtKB {GO:0008625=PMID:11741985, GO:0005515=PMID:11741985, GO:0006396=PMID:11741985, GO:0016075=PMID:11741985, GO:0019725=PMID:11741985, GO:2001238=PMID:11741985, GO:0030262=PMID:11741985, GO:0005730=GO_REF:0000052, GO:0030159=PMID:11741985, GO:0005634=GO_REF:0000052, GO:0042981=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037, GO:0035556=PMID:11741985, GO:0045892=PMID:11741985} Q8WXF8 DNA-binding death effector domain-containing protein 2 protein 20111111 {GO:0008625=IMP, GO:0005515=IPI, GO:0006396=NAS, GO:0016075=NAS, GO:0019725=NAS, GO:2001238=IMP, GO:0030262=IDA, GO:0005730=IDA, GO:0030159=NAS, GO:0005634=IDA, GO:0042981=IEA, GO:0003677=IEA, GO:0006351=IEA, GO:0035556=NAS, GO:0045892=NAS} RNA processing, apoptotic nuclear changes, cellular homeostasis, extrinsic apoptotic signaling pathway via death domain receptors, intracellular signal transduction, negative regulation of transcription, DNA-dependent, positive regulation of extrinsic apoptotic signaling pathway, rRNA catabolic process, regulation of apoptotic process, transcription, DNA-dependent nucleolus, nucleus DNA binding, protein binding, receptor signaling complex scaffold activity NOT Human DEF6 HPA UniProtKB {GO:0005737=GO_REF:0000039, GO:0005543=GO_REF:0000002, GO:0005886=GO_REF:0000039, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052} Q9H4E7 Differentially expressed in FDCP 6 homolog protein 20110516 {GO:0005737=IEA, GO:0005543=IEA, GO:0005886=IEA, GO:0005730=IDA, GO:0005634=IDA} cytoplasm, nucleolus, nucleus, plasma membrane phospholipid binding NOT Human DEF8 InterPro UniProtKB {GO:0035556=GO_REF:0000002, GO:0008270=GO_REF:0000002} Q6ZN54 Differentially expressed in FDCP 8 homolog protein 20130413 {GO:0035556=IEA, GO:0008270=IEA} intracellular signal transduction zinc ion binding Human InterPro:IPR002219 DEFA1 Reactome UniProtKB {GO:0006955=PMID:10914484, GO:0051607=GO_REF:0000037, GO:0006935=PMID:10914484, GO:0005796=Reactome:REACT_115691, GO:0045087=Reactome:REACT_6802, GO:0050832=GO_REF:0000037, GO:0031640=GO_REF:0000037, GO:0005576=Reactome:REACT_116084, GO:0035578=Reactome:REACT_115688, GO:0005615=GO_REF:0000002, GO:0042742=GO_REF:0000037} P59665 Neutrophil defensin 1 protein 20110729 {GO:0006955=TAS, GO:0051607=IEA, GO:0006935=TAS, GO:0005796=TAS, GO:0045087=TAS, GO:0050832=IEA, GO:0031640=IEA, GO:0005576=TAS, GO:0035578=TAS, GO:0005615=IEA, GO:0042742=IEA} chemotaxis, defense response to bacterium, defense response to fungus, defense response to virus, immune response, innate immune response, killing of cells of other organism Golgi lumen, azurophil granule lumen, extracellular region, extracellular space Human DEFA3 Reactome UniProtKB {GO:0051607=GO_REF:0000037, GO:0005796=Reactome:REACT_115691, GO:0045087=Reactome:REACT_6802, GO:0050832=GO_REF:0000037, GO:0031640=GO_REF:0000037, GO:0005576=Reactome:REACT_116084, GO:0035578=Reactome:REACT_115688, GO:0005615=GO_REF:0000002, GO:0042742=GO_REF:0000037} P59666 Neutrophil defensin 3 protein 20110729 {GO:0051607=IEA, GO:0005796=TAS, GO:0045087=TAS, GO:0050832=IEA, GO:0031640=IEA, GO:0005576=TAS, GO:0035578=TAS, GO:0005615=IEA, GO:0042742=IEA} defense response to bacterium, defense response to fungus, defense response to virus, innate immune response, killing of cells of other organism Golgi lumen, azurophil granule lumen, extracellular region, extracellular space Human DEFA4 Reactome UniProtKB {GO:0005796=Reactome:REACT_115619, GO:0045087=Reactome:REACT_6802, GO:0050832=GO_REF:0000037, GO:0031640=GO_REF:0000037, GO:0005576=Reactome:REACT_115822, GO:0005615=GO_REF:0000002, GO:0042742=GO_REF:0000037} P12838 Neutrophil defensin 4 protein 20110727 {GO:0005796=TAS, GO:0045087=TAS, GO:0050832=IEA, GO:0031640=IEA, GO:0005576=TAS, GO:0005615=IEA, GO:0042742=IEA} defense response to bacterium, defense response to fungus, innate immune response, killing of cells of other organism Golgi lumen, extracellular region, extracellular space Human DEFA5 Reactome UniProtKB {GO:0030133=GO_REF:0000039, GO:0005796=Reactome:REACT_115904, GO:0045087=Reactome:REACT_6802, GO:0050832=GO_REF:0000037, GO:0031640=GO_REF:0000037, GO:0005576=Reactome:REACT_116162, GO:0005615=GO_REF:0000002, GO:0034774=Reactome:REACT_115910, GO:0042742=GO_REF:0000037} Q01523 Defensin-5 protein 20110729 {GO:0030133=IEA, GO:0005796=TAS, GO:0045087=TAS, GO:0050832=IEA, GO:0031640=IEA, GO:0005576=TAS, GO:0005615=IEA, GO:0034774=TAS, GO:0042742=IEA} defense response to bacterium, defense response to fungus, innate immune response, killing of cells of other organism Golgi lumen, extracellular region, extracellular space, secretory granule lumen, transport vesicle Human DEFA6 Reactome UniProtKB {GO:0005796=Reactome:REACT_115619, GO:0045087=Reactome:REACT_6802, GO:0050832=GO_REF:0000037, GO:0031640=GO_REF:0000037, GO:0005576=Reactome:REACT_115822, GO:0005615=GO_REF:0000002, GO:0042742=GO_REF:0000037} Q01524 Defensin-6 protein 20110729 {GO:0005796=TAS, GO:0045087=TAS, GO:0050832=IEA, GO:0031640=IEA, GO:0005576=TAS, GO:0005615=IEA, GO:0042742=IEA} defense response to bacterium, defense response to fungus, innate immune response, killing of cells of other organism Golgi lumen, extracellular region, extracellular space Human DEFB1 Reactome UniProtKB {GO:0009617=PMID:12054642, GO:0006955=PMID:10521347, GO:0002526=GO_REF:0000019, GO:0007186=PMID:10521347, GO:0006935=PMID:10521347, GO:0005796=Reactome:REACT_116066, GO:0045087=Reactome:REACT_6802, GO:0005576=Reactome:REACT_115591, GO:0033574=GO_REF:0000019, GO:0042742=GO_REF:0000037} P60022 Beta-defensin 1 protein 20130301 {GO:0009617=IDA, GO:0006955=TAS, GO:0002526=IEA, GO:0007186=TAS, GO:0006935=TAS, GO:0005796=TAS, GO:0045087=TAS, GO:0005576=TAS, GO:0033574=IEA, GO:0042742=IEA} G-protein coupled receptor signaling pathway, acute inflammatory response, chemotaxis, defense response to bacterium, immune response, innate immune response, response to bacterium, response to testosterone stimulus Golgi lumen, extracellular region Human DEFB103A Reactome UniProtKB {GO:0006965=PMID:11085990, GO:0005796=Reactome:REACT_116066, GO:0045087=Reactome:REACT_6802, GO:0005576=Reactome:REACT_116066, GO:0042742=GO_REF:0000037} P81534 Beta-defensin 103 protein 20110729 {GO:0006965=TAS, GO:0005796=TAS, GO:0045087=TAS, GO:0005576=TAS, GO:0042742=IEA} defense response to bacterium, innate immune response, positive regulation of biosynthetic process of antibacterial peptides active against Gram-positive bacteria Golgi lumen, extracellular region Human DEFB103B null null {} null null null null {} null null null DEFB104A UniProtKB UniProtKB {GO:0005576=GO_REF:0000039, GO:0042742=GO_REF:0000037} Q8WTQ1 Beta-defensin 104 protein 20130413 {GO:0005576=IEA, GO:0042742=IEA} defense response to bacterium extracellular region Human UniProtKB-SubCell:SL-0243 DEFB127 UniProtKB UniProtKB {GO:0045087=PMID:10588992, GO:0005576=GO_REF:0000039, GO:0005575=GO_REF:0000015, GO:0042742=PMID:10588992} Q9H1M4 Beta-defensin 127 protein 20040129 {GO:0045087=TAS, GO:0005576=IEA, GO:0005575=ND, GO:0042742=TAS} defense response to bacterium, innate immune response cellular_component, extracellular region Human DEFB4A Reactome UniProtKB {GO:0006955=PMID:10521347, GO:0007186=PMID:10521347, GO:0006935=PMID:10521347, GO:0005796=Reactome:REACT_116066, GO:0045087=Reactome:REACT_6802, GO:0005576=Reactome:REACT_115754, GO:0042742=GO_REF:0000037} O15263 Beta-defensin 4A protein 20130301 {GO:0006955=TAS, GO:0007186=TAS, GO:0006935=TAS, GO:0005796=TAS, GO:0045087=TAS, GO:0005576=TAS, GO:0042742=IEA} G-protein coupled receptor signaling pathway, chemotaxis, defense response to bacterium, immune response, innate immune response Golgi lumen, extracellular region Human DEGS1 Reactome UniProtKB {GO:0006665=Reactome:REACT_19323, GO:0006636=PMID:9188692, GO:0005783=PMID:9188692, GO:0030148=Reactome:REACT_115810, GO:0009055=PMID:9188692, GO:0044281=Reactome:REACT_111217, GO:0005739=GO_REF:0000039, GO:0016020=PMID:9188692, GO:0005887=PMID:9188692, GO:0005789=Reactome:REACT_19261, GO:0006633=GO_REF:0000002, GO:0016021=GO_REF:0000002, GO:0016705=GO_REF:0000002} O15121 Sphingolipid delta(4)-desaturase DES1 protein 20130301 {GO:0006665=TAS, GO:0006636=TAS, GO:0005783=TAS, GO:0030148=TAS, GO:0009055=TAS, GO:0044281=TAS, GO:0005739=IEA, GO:0016020=TAS, GO:0005887=TAS, GO:0005789=TAS, GO:0006633=IEA, GO:0016021=IEA, GO:0016705=IEA} fatty acid biosynthetic process, small molecule metabolic process, sphingolipid biosynthetic process, sphingolipid metabolic process, unsaturated fatty acid biosynthetic process endoplasmic reticulum, endoplasmic reticulum membrane, integral to membrane, integral to plasma membrane, membrane, mitochondrion electron carrier activity, oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen Human DEK PINC UniProtKB {GO:2001032=GO_REF:0000019, GO:0007165=PMID:9050861, GO:0042393=PMID:12140263, GO:0006357=PMID:9050861, GO:0006366=PMID:9050861, GO:2000779=PMID:21653549, GO:0005634=PMID:21653549, GO:0003676=GO_REF:0000002, GO:0019079=PMID:9050861, GO:0003677=GO_REF:0000037, GO:0016568=GO_REF:0000037} P35659 Protein DEK protein 20031119 {GO:2001032=IEA, GO:0007165=TAS, GO:0042393=IDA, GO:0006357=TAS, GO:0006366=TAS, GO:2000779=IMP, GO:0005634=IDA, GO:0003676=IEA, GO:0019079=TAS, GO:0003677=IEA, GO:0016568=IEA} chromatin modification, regulation of double-strand break repair, regulation of double-strand break repair via nonhomologous end joining, regulation of transcription from RNA polymerase II promoter, signal transduction, transcription from RNA polymerase II promoter, viral genome replication nucleus DNA binding, histone binding, nucleic acid binding Human DENND1A UniProtKB UniProtKB {GO:0017112=PMID:20937701, GO:0042734=GO_REF:0000039, GO:0030665=GO_REF:0000039, GO:0017124=GO_REF:0000019, GO:0030054=GO_REF:0000037, GO:0005886=GO_REF:0000037, GO:0030136=PMID:20937701, GO:0043025=GO_REF:0000019, GO:0048488=GO_REF:0000019, GO:0015031=GO_REF:0000037, GO:0030425=GO_REF:0000019, GO:0006897=PMID:20937701} Q8TEH3 DENN domain-containing protein 1A protein 20121004 {GO:0017112=IDA, GO:0042734=IEA, GO:0030665=IEA, GO:0017124=IEA, GO:0030054=IEA, GO:0005886=IEA, GO:0030136=IDA, GO:0043025=IEA, GO:0048488=IEA, GO:0015031=IEA, GO:0030425=IEA, GO:0006897=IMP} endocytosis, protein transport, synaptic vesicle endocytosis cell junction, clathrin-coated vesicle, clathrin-coated vesicle membrane, dendrite, neuronal cell body, plasma membrane, presynaptic membrane Rab guanyl-nucleotide exchange factor activity, SH3 domain binding Human DENND1C UniProtKB UniProtKB {GO:0017112=PMID:20937701, GO:0030136=GO_REF:0000039, GO:0005829=GO_REF:0000039} Q8IV53 DENN domain-containing protein 1C protein 20121004 {GO:0017112=IDA, GO:0030136=IEA, GO:0005829=IEA} clathrin-coated vesicle, cytosol Rab guanyl-nucleotide exchange factor activity Human DENND2A UniProtKB UniProtKB {GO:0017112=PMID:20937701, GO:0005737=GO_REF:0000037, GO:0042147=PMID:20937701, GO:0015629=PMID:20937701, GO:0015031=GO_REF:0000037} Q9ULE3 DENN domain-containing protein 2A protein 20121004 {GO:0017112=IDA, GO:0005737=IEA, GO:0042147=IMP, GO:0015629=IDA, GO:0015031=IEA} protein transport, retrograde transport, endosome to Golgi actin cytoskeleton, cytoplasm Rab guanyl-nucleotide exchange factor activity Human DENND2D UniProtKB UniProtKB {GO:0017112=PMID:20937701, GO:0005737=GO_REF:0000039} Q9H6A0 DENN domain-containing protein 2D protein 20121004 {GO:0017112=IDA, GO:0005737=IEA} cytoplasm Rab guanyl-nucleotide exchange factor activity Human DENND3 ENSEMBL UniProtKB {GO:0017112=GO_REF:0000019, GO:0008333=GO_REF:0000024, GO:0044257=GO_REF:0000019} B3KRG7 cDNA FLJ34237 fis, clone FCBBF3027328 protein 20130413 {GO:0017112=IEA, GO:0008333=ISS, GO:0044257=IEA} cellular protein catabolic process, endosome to lysosome transport Rab guanyl-nucleotide exchange factor activity Human Ensembl:ENSMUSP00000046774 DENND4A UniProtKB UniProtKB {GO:0017112=PMID:20937701, GO:0006355=PMID:8056341, GO:0005634=GO_REF:0000029, GO:0003677=PMID:8056341, GO:0006351=GO_REF:0000037} Q7Z401 C-myc promoter-binding protein protein 20121004 {GO:0017112=IDA, GO:0006355=NAS, GO:0005634=NAS, GO:0003677=NAS, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus DNA binding, Rab guanyl-nucleotide exchange factor activity Human DENND4C UniProtKB UniProtKB {GO:0017112=PMID:20937701, GO:0032869=GO_REF:0000024, GO:0005886=GO_REF:0000024, GO:0032593=GO_REF:0000024, GO:0015031=GO_REF:0000037, GO:0072659=GO_REF:0000024, GO:0030659=GO_REF:0000039, GO:0005829=GO_REF:0000024, GO:0030904=GO_REF:0000019} Q5VZ89 DENN domain-containing protein 4C protein 20121005 {GO:0017112=IDA, GO:0032869=ISS, GO:0005886=ISS, GO:0032593=ISS, GO:0015031=IEA, GO:0072659=ISS, GO:0030659=IEA, GO:0005829=ISS, GO:0030904=IEA} cellular response to insulin stimulus, protein localization to plasma membrane, protein transport cytoplasmic vesicle membrane, cytosol, insulin-responsive compartment, plasma membrane, retromer complex Rab guanyl-nucleotide exchange factor activity Human UniProtKB:A6H8H2 DENND5A UniProtKB UniProtKB {GO:0017112=PMID:20937701, GO:0005262=GO_REF:0000033, GO:0017137=GO_REF:0000019, GO:0005794=GO_REF:0000019, GO:0050982=GO_REF:0000033, GO:0016020=GO_REF:0000033} Q6IQ26 DENN domain-containing protein 5A protein 20121004 {GO:0017112=IDA, GO:0005262=IBA, GO:0017137=IEA, GO:0005794=IEA, GO:0050982=IBA, GO:0016020=IBA} detection of mechanical stimulus Golgi apparatus, membrane Rab GTPase binding, Rab guanyl-nucleotide exchange factor activity, calcium channel activity Human DENND5B UniProtKB UniProtKB {GO:0017112=PMID:20937701, GO:0005262=GO_REF:0000033, GO:0050982=GO_REF:0000033, GO:0016020=GO_REF:0000033, GO:0016021=GO_REF:0000037} Q6ZUT9 DENN domain-containing protein 5B protein 20121004 {GO:0017112=IDA, GO:0005262=IBA, GO:0050982=IBA, GO:0016020=IBA, GO:0016021=IEA} detection of mechanical stimulus integral to membrane, membrane Rab guanyl-nucleotide exchange factor activity, calcium channel activity Human DENR IntAct UniProtKB {GO:0005515=PMID:20195357, GO:0003674=GO_REF:0000015, GO:0008150=GO_REF:0000015, GO:0003743=GO_REF:0000002, GO:0005575=GO_REF:0000015} O43583 Density-regulated protein protein 20130415 {GO:0005515=IPI, GO:0003674=ND, GO:0008150=ND, GO:0003743=IEA, GO:0005575=ND} biological_process cellular_component molecular_function, protein binding, translation initiation factor activity Human UniProtKB:Q8WX92 DEPDC1 UniProtKB UniProtKB {GO:0005515=PMID:20587513, GO:0035556=GO_REF:0000002, GO:0017053=PMID:20587513, GO:0005634=PMID:20587513, GO:0045892=PMID:20587513, GO:0006351=GO_REF:0000037, GO:0005096=GO_REF:0000037} Q5TB30 DEP domain-containing protein 1A protein 20101214 {GO:0005515=IPI, GO:0035556=IEA, GO:0017053=IDA, GO:0005634=IDA, GO:0045892=IDA, GO:0006351=IEA, GO:0005096=IEA} intracellular signal transduction, negative regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus, transcriptional repressor complex GTPase activator activity, protein binding Human DEPDC1B Reactome UniProtKB {GO:0035556=GO_REF:0000002, GO:0005622=GO_REF:0000002, GO:0051056=Reactome:REACT_11051, GO:0007264=Reactome:REACT_11044, GO:0005829=Reactome:REACT_9982, GO:0005096=GO_REF:0000037} Q8WUY9 DEP domain-containing protein 1B protein 20130301 {GO:0035556=IEA, GO:0005622=IEA, GO:0051056=TAS, GO:0007264=TAS, GO:0005829=TAS, GO:0005096=IEA} intracellular signal transduction, regulation of small GTPase mediated signal transduction, small GTPase mediated signal transduction cytosol, intracellular GTPase activator activity Human DEPDC5 InterPro UniProtKB {GO:0035556=GO_REF:0000002} O75140 DEP domain-containing protein 5 protein 20130413 {GO:0035556=IEA} intracellular signal transduction Human InterPro:IPR000591 DEPDC7 Reactome UniProtKB {GO:0035556=GO_REF:0000002, GO:0051056=Reactome:REACT_11051, GO:0008150=GO_REF:0000015, GO:0003674=GO_REF:0000015, GO:0007264=Reactome:REACT_11044, GO:0005575=GO_REF:0000015, GO:0005829=Reactome:REACT_9982} Q96QD5 DEP domain-containing protein 7 protein 20130301 {GO:0035556=IEA, GO:0051056=TAS, GO:0008150=ND, GO:0003674=ND, GO:0007264=TAS, GO:0005575=ND, GO:0005829=TAS} biological_process, intracellular signal transduction, regulation of small GTPase mediated signal transduction, small GTPase mediated signal transduction cellular_component, cytosol molecular_function Human DEPTOR IntAct UniProtKB {GO:0005622=GO_REF:0000054, GO:0005515=PMID:19446321, GO:0035556=GO_REF:0000002, GO:0045792=PMID:19446321, GO:0032007=PMID:19446321, GO:0042981=PMID:19446321, GO:0006469=PMID:19446321} Q8TB45 DEP domain-containing mTOR-interacting protein protein 20130415 {GO:0005622=IDA, GO:0005515=IPI, GO:0035556=IEA, GO:0045792=IMP, GO:0032007=IMP, GO:0042981=IMP, GO:0006469=IMP} intracellular signal transduction, negative regulation of TOR signaling cascade, negative regulation of cell size, negative regulation of protein kinase activity, regulation of apoptotic process intracellular protein binding Human UniProtKB:P42346 DERA UniProtKB UniProtKB {GO:0009264=GO_REF:0000002, GO:0005737=GO_REF:0000002, GO:0004139=PMID:9226884, GO:0046121=PMID:9226884, GO:0046386=GO_REF:0000041, GO:0005575=GO_REF:0000015} Q9Y315 Putative deoxyribose-phosphate aldolase protein 20081106 {GO:0009264=IEA, GO:0005737=IEA, GO:0004139=IDA, GO:0046121=IDA, GO:0046386=IEA, GO:0005575=ND} deoxyribonucleoside catabolic process, deoxyribonucleotide catabolic process, deoxyribose phosphate catabolic process cellular_component, cytoplasm deoxyribose-phosphate aldolase activity Human DERL1 HPA UniProtKB {GO:0006986=PMID:15215855, GO:0005515=PMID:18555783, GO:0042288=PMID:15215855, GO:0019060=PMID:15215856, GO:0005783=GO_REF:0000052, GO:0005770=GO_REF:0000019, GO:0030970=PMID:15215855, GO:0030176=PMID:15215856, GO:0030433=PMID:15215856, GO:0045184=PMID:15215856, GO:0030968=PMID:15215856, GO:0004872=PMID:15215856, GO:0016021=PMID:15215855, GO:0034620=GO_REF:0000019, GO:0005769=GO_REF:0000019} Q9BUN8 Derlin-1 protein 20090616 {GO:0006986=IMP, GO:0005515=IPI, GO:0042288=IDA, GO:0019060=TAS, GO:0005783=IDA, GO:0005770=IEA, GO:0030970=IMP, GO:0030176=IDA, GO:0030433=IDA, GO:0045184=TAS, GO:0030968=IDA, GO:0004872=NAS, GO:0016021=IDA, GO:0034620=IEA, GO:0005769=IEA} ER-associated protein catabolic process, cellular response to unfolded protein, endoplasmic reticulum unfolded protein response, establishment of protein localization, intracellular transport of viral proteins in host cell, response to unfolded protein, retrograde protein transport, ER to cytosol early endosome, endoplasmic reticulum, integral to endoplasmic reticulum membrane, integral to membrane, late endosome MHC class I protein binding, protein binding, receptor activity Human DERL2 UniProtKB UniProtKB {GO:0005515=PMID:16449189, GO:0008284=PMID:11500051, GO:0005783=PMID:15215855, GO:0030307=PMID:11500051, GO:0005770=GO_REF:0000019, GO:0030970=PMID:16449189, GO:0030176=PMID:16449189, GO:0030433=PMID:16449189, GO:0005769=GO_REF:0000019, GO:0030968=PMID:16449189} Q9GZP9 Derlin-2 protein 20120708 {GO:0005515=IPI, GO:0008284=IDA, GO:0005783=IDA, GO:0030307=IDA, GO:0005770=IEA, GO:0030970=IMP, GO:0030176=IDA, GO:0030433=IMP, GO:0005769=IEA, GO:0030968=IDA} ER-associated protein catabolic process, endoplasmic reticulum unfolded protein response, positive regulation of cell growth, positive regulation of cell proliferation, retrograde protein transport, ER to cytosol early endosome, endoplasmic reticulum, integral to endoplasmic reticulum membrane, late endosome protein binding Human UniProtKB:Q92611 DERL3 UniProtKB UniProtKB {GO:0005515=PMID:16449189, GO:0030176=PMID:16449189, GO:0030433=PMID:22607976, GO:0018279=PMID:22607976, GO:0030968=PMID:16449189} Q96Q80 Derlin-3 protein 20120708 {GO:0005515=IPI, GO:0030176=IDA, GO:0030433=IMP, GO:0018279=IMP, GO:0030968=IDA} ER-associated protein catabolic process, endoplasmic reticulum unfolded protein response, protein N-linked glycosylation via asparagine integral to endoplasmic reticulum membrane protein binding Human UniProtKB:Q92611 DES BHF-UCL UniProtKB {GO:0005882=GO_REF:0000019, GO:0005515=PMID:11353857, GO:0008092=PMID:11309420, GO:0030018=PMID:9415431, GO:0031594=GO_REF:0000019, GO:0030049=Reactome:REACT_16969, GO:0008016=PMID:9697706, GO:0005829=Reactome:REACT_17057, GO:0005916=GO_REF:0000019, GO:0042383=GO_REF:0000019, GO:0006936=PMID:9697706, GO:0007010=PMID:9736733, GO:0005200=PMID:9736733} P17661 Desmin protein 20120508 {GO:0005882=IEA, GO:0005515=IPI, GO:0008092=IPI, GO:0030018=IDA, GO:0031594=IEA, GO:0030049=TAS, GO:0008016=TAS, GO:0005829=TAS, GO:0005916=IEA, GO:0042383=IEA, GO:0006936=TAS, GO:0007010=TAS, GO:0005200=TAS} cytoskeleton organization, muscle contraction, muscle filament sliding, regulation of heart contraction Z disc, cytosol, fascia adherens, intermediate filament, neuromuscular junction, sarcolemma cytoskeletal protein binding, protein binding, structural constituent of cytoskeleton Human UniProtKB:Q04020 DET1 UniProtKB UniProtKB {GO:0005634=GO_REF:0000039} Q7L5Y6 DET1 homolog protein 20130413 {GO:0005634=IEA} nucleus Human UniProtKB-SubCell:SL-0191 DEXI null null {} null null null null {} null null null DFFA HPA UniProtKB {GO:0000790=PMID:19882353, GO:0043066=PMID:9564035, GO:0006915=Reactome:REACT_578, GO:0005634=GO_REF:0000052, GO:0006917=GO_REF:0000019, GO:0006921=Reactome:REACT_995, GO:0005829=Reactome:REACT_13756, GO:0005622=GO_REF:0000002, GO:0035556=PMID:9108473, GO:0007165=GO_REF:0000002, GO:0005737=GO_REF:0000052, GO:0004536=PMID:9108473, GO:0006309=Reactome:REACT_1213, GO:0005654=Reactome:REACT_13689} O00273 DNA fragmentation factor subunit alpha protein 20111111 {GO:0000790=IDA, GO:0043066=IDA, GO:0006915=TAS, GO:0005634=IDA, GO:0006917=IEA, GO:0006921=TAS, GO:0005829=TAS, GO:0005622=IEA, GO:0035556=TAS, GO:0007165=IEA, GO:0005737=IDA, GO:0004536=TAS, GO:0006309=TAS, GO:0005654=TAS} apoptotic DNA fragmentation, apoptotic process, cellular component disassembly involved in execution phase of apoptosis, induction of apoptosis, intracellular signal transduction, negative regulation of apoptotic process, signal transduction cytoplasm, cytosol, intracellular, nuclear chromatin, nucleoplasm, nucleus deoxyribonuclease activity Human DFFB InterPro UniProtKB {GO:0000790=PMID:19882353, GO:0006915=GO_REF:0000002, GO:0005634=GO_REF:0000019, GO:0006917=GO_REF:0000019, GO:0003677=GO_REF:0000019, GO:0006921=Reactome:REACT_995, GO:0005829=Reactome:REACT_13756, GO:0035556=PMID:9108473, GO:0005622=GO_REF:0000002, GO:0004516=GO_REF:0000019, GO:0005737=GO_REF:0000002, GO:0004536=GO_REF:0000019, GO:0016787=GO_REF:0000002, GO:0006309=GO_REF:0000019, GO:0030263=PMID:10959840, GO:0005654=Reactome:REACT_13708, GO:0019899=PMID:10959840} Q96P73 DNAation factor, 40kDa, beta polypeptide (Caspase-activated DNase), isoform CRA_d protein 20130413 {GO:0000790=IDA, GO:0006915=IEA, GO:0005634=IEA, GO:0006917=IEA, GO:0003677=IEA, GO:0006921=TAS, GO:0005829=TAS, GO:0035556=TAS, GO:0005622=IEA, GO:0004516=IEA, GO:0005737=IEA, GO:0004536=IEA, GO:0016787=IEA, GO:0006309=IEA, GO:0030263=IDA, GO:0005654=TAS, GO:0019899=IPI} apoptotic DNA fragmentation, apoptotic chromosome condensation, apoptotic process, cellular component disassembly involved in execution phase of apoptosis, induction of apoptosis, intracellular signal transduction cytoplasm, cytosol, intracellular, nuclear chromatin, nucleoplasm, nucleus DNA binding, deoxyribonuclease activity, enzyme binding, hydrolase activity, nicotinate phosphoribosyltransferase activity Human InterPro:IPR003508 DFNA5 HPA UniProtKB {GO:0005737=GO_REF:0000052, GO:0008285=PMID:18223688, GO:0060113=GO_REF:0000019, GO:0007605=PMID:9771715, GO:0006915=PMID:21522185, GO:0006917=PMID:21522185} O60443 Non-syndromic hearing impairment protein 5 protein 20081203 {GO:0005737=IDA, GO:0008285=IDA, GO:0060113=IEA, GO:0007605=TAS, GO:0006915=IDA, GO:0006917=IDA} apoptotic process, induction of apoptosis, inner ear receptor cell differentiation, negative regulation of cell proliferation, sensory perception of sound cytoplasm Human DFNB31 HGNC UniProtKB {GO:0005515=PMID:23023331, GO:0005929=GO_REF:0000019, GO:0005737=PMID:16434480, GO:0060122=GO_REF:0000024, GO:0001895=PMID:17171570, GO:0002142=GO_REF:0000019, GO:0007605=PMID:17171570, GO:0005884=GO_REF:0000019, GO:0032420=GO_REF:0000024, GO:0050953=PMID:17171570, GO:0030426=GO_REF:0000039} Q9P202 Whirlin protein 20070807 {GO:0005515=IPI, GO:0005929=IEA, GO:0005737=IDA, GO:0060122=ISS, GO:0001895=IMP, GO:0002142=IEA, GO:0007605=IMP, GO:0005884=IEA, GO:0032420=ISS, GO:0050953=IMP, GO:0030426=IEA} inner ear receptor stereocilium organization, retina homeostasis, sensory perception of light stimulus, sensory perception of sound actin filament, cilium, cytoplasm, growth cone, stereocilia ankle link complex, stereocilium protein binding Human DGAT1 BHF-UCL UniProtKB {GO:0008374=GO_REF:0000002, GO:0016746=PMID:9756920, GO:0019915=GO_REF:0000024, GO:0003846=GO_REF:0000019, GO:0055089=GO_REF:0000019, GO:0050252=GO_REF:0000003, GO:0044281=Reactome:REACT_111217, GO:0034379=PMID:15308631, GO:0035336=GO_REF:0000024, GO:0019432=Reactome:REACT_1190, GO:0005789=Reactome:REACT_121007, GO:0006641=PMID:9756920, GO:0004144=Reactome:REACT_659, GO:0036155=Reactome:REACT_121122, GO:0016021=GO_REF:0000024, GO:0006644=Reactome:REACT_120870, GO:0044255=Reactome:REACT_22279, GO:0046339=GO_REF:0000024, GO:0046474=Reactome:REACT_121401} O75907 Diacylglycerol O-acyltransferase 1 protein 20111130 {GO:0008374=IEA, GO:0016746=TAS, GO:0019915=ISS, GO:0003846=IEA, GO:0055089=IEA, GO:0050252=IEA, GO:0044281=TAS, GO:0034379=IMP, GO:0035336=ISS, GO:0019432=TAS, GO:0005789=TAS, GO:0006641=TAS, GO:0004144=EXP, GO:0036155=TAS, GO:0016021=ISS, GO:0006644=TAS, GO:0044255=TAS, GO:0046339=ISS, GO:0046474=TAS} acylglycerol acyl-chain remodeling, cellular lipid metabolic process, diacylglycerol metabolic process, fatty acid homeostasis, glycerophospholipid biosynthetic process, lipid storage, long-chain fatty-acyl-CoA metabolic process, phospholipid metabolic process, small molecule metabolic process, triglyceride biosynthetic process, triglyceride metabolic process, very-low-density lipoprotein particle assembly endoplasmic reticulum membrane, integral to membrane 2-acylglycerol O-acyltransferase activity, O-acyltransferase activity, diacylglycerol O-acyltransferase activity, retinol O-fatty-acyltransferase activity, transferase activity, transferring acyl groups Human UniProtKB:Q9Z2A7 DGCR14 UniProtKB UniProtKB {GO:0003674=GO_REF:0000015, GO:0000398=PMID:11991638, GO:0005634=PMID:8703114, GO:0071013=PMID:11991638, GO:0007399=PMID:8703114} Q96DF8 Protein DGCR14 protein 20110302 {GO:0003674=ND, GO:0000398=IC, GO:0005634=ISS, GO:0071013=IDA, GO:0007399=ISS} mRNA splicing, via spliceosome, nervous system development catalytic step 2 spliceosome, nucleus molecular_function Human DGCR2 PINC UniProtKB {GO:0009887=PMID:7655455, GO:0030246=GO_REF:0000002, GO:0016021=GO_REF:0000037, GO:0007155=GO_REF:0000037} P98153 Integral membrane protein DGCR2/IDD protein 20031120 {GO:0009887=TAS, GO:0030246=IEA, GO:0016021=IEA, GO:0007155=IEA} cell adhesion, organ morphogenesis integral to membrane carbohydrate binding Human DGCR6 PINC UniProtKB {GO:0003674=GO_REF:0000015, GO:0005578=PMID:8733130, GO:0009887=PMID:8733130, GO:0005634=GO_REF:0000039, GO:0007155=PMID:8733130} Q14129 Protein DGCR6 protein 20031120 {GO:0003674=ND, GO:0005578=TAS, GO:0009887=TAS, GO:0005634=IEA, GO:0007155=TAS} cell adhesion, organ morphogenesis nucleus, proteinaceous extracellular matrix molecular_function Human DGCR6L UniProtKB UniProtKB {GO:0005634=GO_REF:0000039} Q9BY27 Protein DGCR6L protein 20130413 {GO:0005634=IEA} nucleus Human UniProtKB-SubCell:SL-0191 DGCR8 HPA UniProtKB {GO:0005515=PMID:15574589, GO:0003725=PMID:17704815, GO:0010467=Reactome:REACT_71, GO:0005737=GO_REF:0000052, GO:0015630=GO_REF:0000052, GO:0031053=PMID:15574589, GO:0005730=GO_REF:0000052, GO:0005654=Reactome:REACT_12414, GO:0005634=GO_REF:0000052, GO:0046872=GO_REF:0000037} Q8WYQ5 Microprocessor complex subunit DGCR8 protein 20101115 {GO:0005515=IPI, GO:0003725=IDA, GO:0010467=TAS, GO:0005737=IDA, GO:0015630=IDA, GO:0031053=IDA, GO:0005730=IDA, GO:0005654=TAS, GO:0005634=IDA, GO:0046872=IEA} gene expression, primary miRNA processing cytoplasm, microtubule cytoskeleton, nucleolus, nucleoplasm, nucleus double-stranded RNA binding, metal ion binding, protein binding Human DGKA UniProtKB UniProtKB {GO:0035556=GO_REF:0000002, GO:0005543=GO_REF:0000019, GO:0005886=Reactome:REACT_19402, GO:0016301=GO_REF:0000038, GO:0007596=Reactome:REACT_604, GO:0005509=GO_REF:0000002, GO:0004143=GO_REF:0000003, GO:0030168=Reactome:REACT_798, GO:0005524=GO_REF:0000037, GO:0046872=GO_REF:0000038, GO:0007205=GO_REF:0000002, GO:0005829=GO_REF:0000019} Q3ZE25 Diacylglycerol kinase alpha protein 20130413 {GO:0035556=IEA, GO:0005543=IEA, GO:0005886=TAS, GO:0016301=IEA, GO:0007596=TAS, GO:0005509=IEA, GO:0004143=IEA, GO:0030168=TAS, GO:0005524=IEA, GO:0046872=IEA, GO:0007205=IEA, GO:0005829=IEA} blood coagulation, intracellular signal transduction, platelet activation, protein kinase C-activating G-protein coupled receptor signaling pathway cytosol, plasma membrane ATP binding, calcium ion binding, diacylglycerol kinase activity, kinase activity, metal ion binding, phospholipid binding Human UniProtKB-KW:KW-0418 DGKB Reactome UniProtKB {GO:0035556=GO_REF:0000002, GO:0005737=GO_REF:0000039, GO:0005886=Reactome:REACT_19402, GO:0007596=Reactome:REACT_604, GO:0005509=GO_REF:0000002, GO:0004143=GO_REF:0000003, GO:0030168=Reactome:REACT_798, GO:0005524=GO_REF:0000037, GO:0007205=GO_REF:0000002} Q9Y6T7 Diacylglycerol kinase beta protein 20130301 {GO:0035556=IEA, GO:0005737=IEA, GO:0005886=TAS, GO:0007596=TAS, GO:0005509=IEA, GO:0004143=IEA, GO:0030168=TAS, GO:0005524=IEA, GO:0007205=IEA} blood coagulation, intracellular signal transduction, platelet activation, protein kinase C-activating G-protein coupled receptor signaling pathway cytoplasm, plasma membrane ATP binding, calcium ion binding, diacylglycerol kinase activity Human DGKD Reactome UniProtKB {GO:0010033=PMID:12200442, GO:0046982=PMID:12200442, GO:0005886=Reactome:REACT_19402, GO:0030168=Reactome:REACT_798, GO:0007275=PMID:12200442, GO:0015031=GO_REF:0000037, GO:0005524=GO_REF:0000037, GO:0042803=PMID:12200442, GO:0046872=GO_REF:0000037, GO:0007205=PMID:12200442, GO:0006897=GO_REF:0000037, GO:0019992=PMID:12200442, GO:0035556=GO_REF:0000002, GO:0007165=PMID:8626538, GO:0005737=PMID:12200442, GO:0005543=GO_REF:0000002, GO:0007173=PMID:12200442, GO:0007596=Reactome:REACT_604, GO:0019932=PMID:12200442, GO:0004143=PMID:12200442, GO:0016049=PMID:12200442, GO:0051260=PMID:12200442, GO:0046339=PMID:12200442} Q16760 Diacylglycerol kinase delta protein 20130301 {GO:0010033=IDA, GO:0046982=IDA, GO:0005886=TAS, GO:0030168=TAS, GO:0007275=NAS, GO:0015031=IEA, GO:0005524=IEA, GO:0042803=IDA, GO:0046872=IEA, GO:0007205=NAS, GO:0006897=IEA, GO:0019992=NAS, GO:0035556=IEA, GO:0007165=TAS, GO:0005737=IDA, GO:0005543=IEA, GO:0007173=NAS, GO:0007596=TAS, GO:0019932=NAS, GO:0004143=IDA, GO:0016049=NAS, GO:0051260=IDA, GO:0046339=IC} blood coagulation, cell growth, diacylglycerol metabolic process, endocytosis, epidermal growth factor receptor signaling pathway, intracellular signal transduction, multicellular organismal development, platelet activation, protein homooligomerization, protein kinase C-activating G-protein coupled receptor signaling pathway, protein transport, response to organic substance, second-messenger-mediated signaling, signal transduction cytoplasm, plasma membrane ATP binding, diacylglycerol binding, diacylglycerol kinase activity, metal ion binding, phospholipid binding, protein heterodimerization activity, protein homodimerization activity Human DGKE UniProtKB UniProtKB {GO:0035556=GO_REF:0000002, GO:0005886=Reactome:REACT_19402, GO:0007596=Reactome:REACT_604, GO:0004143=GO_REF:0000003, GO:0030168=Reactome:REACT_798, GO:0008654=PMID:8626589, GO:0016021=GO_REF:0000037, GO:0005524=GO_REF:0000037, GO:0046872=GO_REF:0000038, GO:0007205=GO_REF:0000002} Q8TBM4 Diacylglycerol kinase epsilon protein 20130413 {GO:0035556=IEA, GO:0005886=TAS, GO:0007596=TAS, GO:0004143=IEA, GO:0030168=TAS, GO:0008654=TAS, GO:0016021=IEA, GO:0005524=IEA, GO:0046872=IEA, GO:0007205=IEA} blood coagulation, intracellular signal transduction, phospholipid biosynthetic process, platelet activation, protein kinase C-activating G-protein coupled receptor signaling pathway integral to membrane, plasma membrane ATP binding, diacylglycerol kinase activity, metal ion binding Human UniProtKB-KW:KW-0479 DGKG HPA UniProtKB {GO:0035556=GO_REF:0000002, GO:0007165=PMID:8034597, GO:0005737=GO_REF:0000052, GO:0005886=GO_REF:0000052, GO:0007596=Reactome:REACT_604, GO:0048666=GO_REF:0000019, GO:0005509=GO_REF:0000002, GO:0004143=GO_REF:0000003, GO:0030168=Reactome:REACT_798, GO:0005524=GO_REF:0000037, GO:0046872=GO_REF:0000038, GO:0007205=GO_REF:0000002} P49619 Diacylglycerol kinase gamma protein 20110516 {GO:0035556=IEA, GO:0007165=TAS, GO:0005737=IDA, GO:0005886=IDA, GO:0007596=TAS, GO:0048666=IEA, GO:0005509=IEA, GO:0004143=IEA, GO:0030168=TAS, GO:0005524=IEA, GO:0046872=IEA, GO:0007205=IEA} blood coagulation, intracellular signal transduction, neuron development, platelet activation, protein kinase C-activating G-protein coupled receptor signaling pathway, signal transduction cytoplasm, plasma membrane ATP binding, calcium ion binding, diacylglycerol kinase activity, metal ion binding Human DGKH HPA UniProtKB {GO:0031965=GO_REF:0000052, GO:0005886=Reactome:REACT_19402, GO:0030168=Reactome:REACT_798, GO:0005634=GO_REF:0000052, GO:0005524=GO_REF:0000037, GO:0051259=PMID:12810723, GO:0007205=PMID:12810723, GO:0046872=GO_REF:0000037, GO:0035556=GO_REF:0000002, GO:0005737=GO_REF:0000052, GO:0005543=GO_REF:0000002, GO:0007596=Reactome:REACT_604, GO:0004143=PMID:12810723, GO:0005768=PMID:12810723} Q86XP1 Diacylglycerol kinase eta protein 20110516 {GO:0031965=IDA, GO:0005886=TAS, GO:0030168=TAS, GO:0005634=IDA, GO:0005524=IEA, GO:0051259=IMP, GO:0007205=IMP, GO:0046872=IEA, GO:0035556=IEA, GO:0005737=IDA, GO:0005543=IEA, GO:0007596=TAS, GO:0004143=IMP, GO:0005768=IDA} blood coagulation, intracellular signal transduction, platelet activation, protein kinase C-activating G-protein coupled receptor signaling pathway, protein oligomerization cytoplasm, endosome, nuclear membrane, nucleus, plasma membrane ATP binding, diacylglycerol kinase activity, metal ion binding, phospholipid binding Human DGKI IntAct UniProtKB {GO:0005515=PMID:17986458, GO:0048471=GO_REF:0000019, GO:0005886=Reactome:REACT_19402, GO:0030168=Reactome:REACT_798, GO:0046579=GO_REF:0000019, GO:0005634=GO_REF:0000039, GO:0005524=GO_REF:0000037, GO:0007205=GO_REF:0000002, GO:0046872=GO_REF:0000037, GO:0035556=GO_REF:0000002, GO:0005737=PMID:9830018, GO:0007596=Reactome:REACT_604, GO:0004143=GO_REF:0000003, GO:0005095=GO_REF:0000019, GO:0017016=GO_REF:0000019, GO:0032317=GO_REF:0000019, GO:0032045=GO_REF:0000019} O75912 Diacylglycerol kinase iota protein 20130415 {GO:0005515=IPI, GO:0048471=IEA, GO:0005886=TAS, GO:0030168=TAS, GO:0046579=IEA, GO:0005634=IEA, GO:0005524=IEA, GO:0007205=IEA, GO:0046872=IEA, GO:0035556=IEA, GO:0005737=TAS, GO:0007596=TAS, GO:0004143=IEA, GO:0005095=IEA, GO:0017016=IEA, GO:0032317=IEA, GO:0032045=IEA} blood coagulation, intracellular signal transduction, platelet activation, positive regulation of Ras protein signal transduction, protein kinase C-activating G-protein coupled receptor signaling pathway, regulation of Rap GTPase activity cytoplasm, guanyl-nucleotide exchange factor complex, nucleus, perinuclear region of cytoplasm, plasma membrane ATP binding, GTPase inhibitor activity, Ras GTPase binding, diacylglycerol kinase activity, metal ion binding, protein binding Human UniProtKB:P40337-3 DGKQ Reactome UniProtKB {GO:0005515=PMID:10066731, GO:0005886=Reactome:REACT_19402, GO:0030168=Reactome:REACT_798, GO:0005634=PMID:17664281, GO:0005524=GO_REF:0000037, GO:0070528=PMID:15632189, GO:0046872=GO_REF:0000037, GO:0007205=GO_REF:0000002, GO:0005829=PMID:10066731, GO:0035556=GO_REF:0000002, GO:0005737=PMID:15632189, GO:0016607=PMID:12799190, GO:0007186=PMID:15632189, GO:0007596=Reactome:REACT_604, GO:0043274=PMID:12799190, GO:0070493=PMID:15632189, GO:0019933=PMID:17664281, GO:0004143=PMID:10066731, GO:0033198=PMID:15632189, GO:0033613=PMID:17664281, GO:0019900=PMID:15632189, GO:0005856=PMID:10066731} P52824 Diacylglycerol kinase theta protein 20130301 {GO:0005515=IPI, GO:0005886=TAS, GO:0030168=TAS, GO:0005634=IDA, GO:0005524=IEA, GO:0070528=IDA, GO:0046872=IEA, GO:0007205=IEA, GO:0005829=IDA, GO:0035556=IEA, GO:0005737=IDA, GO:0016607=IDA, GO:0007186=IMP, GO:0007596=TAS, GO:0043274=IPI, GO:0070493=IDA, GO:0019933=IDA, GO:0004143=IDA, GO:0033198=IDA, GO:0033613=IPI, GO:0019900=IPI, GO:0005856=IDA} G-protein coupled receptor signaling pathway, blood coagulation, cAMP-mediated signaling, intracellular signal transduction, platelet activation, protein kinase C signaling cascade, protein kinase C-activating G-protein coupled receptor signaling pathway, response to ATP, thrombin receptor signaling pathway cytoplasm, cytoskeleton, cytosol, nuclear speck, nucleus, plasma membrane ATP binding, activating transcription factor binding, diacylglycerol kinase activity, kinase binding, metal ion binding, phospholipase binding, protein binding Human DGKZ HPA UniProtKB {GO:0004857=GO_REF:0000019, GO:0005515=PMID:17664281, GO:0005886=Reactome:REACT_19402, GO:0005730=GO_REF:0000052, GO:0030168=Reactome:REACT_798, GO:0005634=GO_REF:0000052, GO:0005524=GO_REF:0000037, GO:0007205=GO_REF:0000002, GO:0046872=GO_REF:0000037, GO:0030027=PMID:15157668, GO:0035556=GO_REF:0000002, GO:0046580=GO_REF:0000019, GO:0005737=GO_REF:0000039, GO:0016477=PMID:15157668, GO:0007596=Reactome:REACT_604, GO:0004143=GO_REF:0000003} Q13574 Diacylglycerol kinase zeta protein 20120912 {GO:0004857=IEA, GO:0005515=IPI, GO:0005886=TAS, GO:0005730=IDA, GO:0030168=TAS, GO:0005634=IDA, GO:0005524=IEA, GO:0007205=IEA, GO:0046872=IEA, GO:0030027=IDA, GO:0035556=IEA, GO:0046580=IEA, GO:0005737=IEA, GO:0016477=NAS, GO:0007596=TAS, GO:0004143=IEA} blood coagulation, cell migration, intracellular signal transduction, negative regulation of Ras protein signal transduction, platelet activation, protein kinase C-activating G-protein coupled receptor signaling pathway cytoplasm, lamellipodium, nucleolus, nucleus, plasma membrane ATP binding, diacylglycerol kinase activity, enzyme inhibitor activity, metal ion binding, protein binding NOT Human DGUOK InterPro UniProtKB {GO:0046070=GO_REF:0000019, GO:0004138=PMID:8706825, GO:0055086=Reactome:REACT_1698, GO:0044281=Reactome:REACT_111217, GO:0019206=Reactome:REACT_2223, GO:0005524=GO_REF:0000002, GO:0009165=Reactome:REACT_2223, GO:0005829=GO_REF:0000019, GO:0005739=PMID:8692979, GO:0006139=GO_REF:0000002, GO:0046122=PMID:8706825, GO:0006144=Reactome:REACT_522, GO:0005759=Reactome:REACT_2223, GO:0016773=GO_REF:0000002, GO:0010977=GO_REF:0000019, GO:0043101=Reactome:REACT_1923, GO:0006468=GO_REF:0000019, GO:0008617=PMID:8692979} Q7L1W9 DGUOK protein protein 20130413 {GO:0046070=IEA, GO:0004138=IDA, GO:0055086=TAS, GO:0044281=TAS, GO:0019206=EXP, GO:0005524=IEA, GO:0009165=EXP, GO:0005829=IEA, GO:0005739=TAS, GO:0006139=IEA, GO:0046122=IDA, GO:0006144=TAS, GO:0005759=TAS, GO:0016773=IEA, GO:0010977=IEA, GO:0043101=TAS, GO:0006468=IEA, GO:0008617=TAS} dGTP metabolic process, guanosine metabolic process, negative regulation of neuron projection development, nucleobase-containing compound metabolic process, nucleobase-containing small molecule metabolic process, nucleotide biosynthetic process, protein phosphorylation, purine deoxyribonucleoside metabolic process, purine nucleobase metabolic process, purine-containing compound salvage, small molecule metabolic process cytosol, mitochondrial matrix, mitochondrion ATP binding, deoxyguanosine kinase activity, nucleoside kinase activity, phosphotransferase activity, alcohol group as acceptor Human InterPro:IPR002624 DHCR24 Reactome UniProtKB {GO:0006695=Reactome:REACT_9405, GO:0008285=GO_REF:0000019, GO:0008762=GO_REF:0000002, GO:0005783=PMID:11007892, GO:0050660=GO_REF:0000002, GO:0007265=GO_REF:0000019, GO:0005634=PMID:15577914, GO:0044281=Reactome:REACT_111217, GO:0016628=PMID:11519011, GO:0005829=GO_REF:0000019, GO:0030539=GO_REF:0000019, GO:0008104=GO_REF:0000019, GO:0050614=GO_REF:0000003, GO:0042605=PMID:15577914, GO:0009888=PMID:12457401, GO:0007050=PMID:15577914, GO:0009725=GO_REF:0000019, GO:0005856=GO_REF:0000019, GO:0043154=PMID:11007892, GO:0006979=PMID:11007892, GO:0042987=GO_REF:0000019, GO:0043066=PMID:15688385, GO:1901214=PMID:16407971, GO:0016614=GO_REF:0000002, GO:0006915=PMID:11007892, GO:0000139=GO_REF:0000039, GO:0005789=Reactome:REACT_10122, GO:0031639=GO_REF:0000019, GO:0043588=GO_REF:0000024, GO:0016021=GO_REF:0000037, GO:0019899=PMID:15577914, GO:0016044=GO_REF:0000019} Q15392 Delta(24)-sterol reductase protein 20130301 {GO:0006695=TAS, GO:0008285=IEA, GO:0008762=IEA, GO:0005783=IDA, GO:0050660=IEA, GO:0007265=IEA, GO:0005634=IDA, GO:0044281=TAS, GO:0016628=IDA, GO:0005829=IEA, GO:0030539=IEA, GO:0008104=IEA, GO:0050614=IEA, GO:0042605=IPI, GO:0009888=IMP, GO:0007050=NAS, GO:0009725=IEA, GO:0005856=IEA, GO:0043154=IDA, GO:0006979=IEP, GO:0042987=IEA, GO:0043066=IDA, GO:1901214=NAS, GO:0016614=IEA, GO:0006915=NAS, GO:0000139=IEA, GO:0005789=TAS, GO:0031639=IEA, GO:0043588=ISS, GO:0016021=IEA, GO:0019899=IPI, GO:0016044=IEA} Ras protein signal transduction, amyloid precursor protein catabolic process, apoptotic process, cell cycle arrest, cellular membrane organization, cholesterol biosynthetic process, male genitalia development, negative regulation of apoptotic process, negative regulation of cell proliferation, negative regulation of cysteine-type endopeptidase activity involved in apoptotic process, plasminogen activation, protein localization, regulation of neuron death, response to hormone stimulus, response to oxidative stress, skin development, small molecule metabolic process, tissue development Golgi membrane, cytoskeleton, cytosol, endoplasmic reticulum, endoplasmic reticulum membrane, integral to membrane, nucleus UDP-N-acetylmuramate dehydrogenase activity, delta24-sterol reductase activity, enzyme binding, flavin adenine dinucleotide binding, oxidoreductase activity, acting on CH-OH group of donors, oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor, peptide antigen binding Human DHCR7 Reactome UniProtKB {GO:0006695=Reactome:REACT_9405, GO:0001568=GO_REF:0000019, GO:0005783=PMID:9878250, GO:0030324=GO_REF:0000019, GO:0045540=GO_REF:0000019, GO:0047598=PMID:9465114, GO:0044281=Reactome:REACT_111217, GO:0009791=GO_REF:0000019, GO:0016628=GO_REF:0000002, GO:0030154=GO_REF:0000019, GO:0043231=GO_REF:0000019, GO:0005640=PMID:9878250, GO:0035264=GO_REF:0000019, GO:0016020=GO_REF:0000002, GO:0042127=GO_REF:0000019, GO:0005789=Reactome:REACT_147864, GO:0016126=GO_REF:0000019, GO:0016021=GO_REF:0000037} Q9UBM7 7-dehydrocholesterol reductase protein 20130301 {GO:0006695=TAS, GO:0001568=IEA, GO:0005783=IDA, GO:0030324=IEA, GO:0045540=IEA, GO:0047598=IDA, GO:0044281=TAS, GO:0009791=IEA, GO:0016628=IEA, GO:0030154=IEA, GO:0043231=IEA, GO:0005640=IDA, GO:0035264=IEA, GO:0016020=IEA, GO:0042127=IEA, GO:0005789=TAS, GO:0016126=IEA, GO:0016021=IEA} blood vessel development, cell differentiation, cholesterol biosynthetic process, lung development, multicellular organism growth, post-embryonic development, regulation of cell proliferation, regulation of cholesterol biosynthetic process, small molecule metabolic process, sterol biosynthetic process endoplasmic reticulum, endoplasmic reticulum membrane, integral to membrane, intracellular membrane-bounded organelle, membrane, nuclear outer membrane 7-dehydrocholesterol reductase activity, oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor Human DHDDS UniProtKB UniProtKB {GO:0005515=PMID:15110773, GO:0005789=GO_REF:0000039, GO:0016765=GO_REF:0000002, GO:0006486=GO_REF:0000041} Q86SQ9 Dehydrodolichyl diphosphate synthase protein 20060208 {GO:0005515=IPI, GO:0005789=IEA, GO:0016765=IEA, GO:0006486=IEA} protein glycosylation endoplasmic reticulum membrane protein binding, transferase activity, transferring alkyl or aryl (other than methyl) groups Human UniProtKB:P61916 DHFR Reactome UniProtKB {GO:0050661=GO_REF:0000002, GO:0050999=Reactome:REACT_12389, GO:0031427=GO_REF:0000037, GO:0006767=Reactome:REACT_11238, GO:0044281=Reactome:REACT_111217, GO:0005575=GO_REF:0000015, GO:0003729=PMID:21876184, GO:0009165=GO_REF:0000029, GO:0005829=Reactome:REACT_11204, GO:0000082=Reactome:REACT_1783, GO:0000083=Reactome:REACT_683, GO:0006766=Reactome:REACT_11193, GO:0008144=PMID:12096917, GO:0046653=PMID:21876184, GO:0046654=GO_REF:0000041, GO:0046655=Reactome:REACT_11167, GO:0046209=Reactome:REACT_12508, GO:0005654=Reactome:REACT_22145, GO:0006545=GO_REF:0000029, GO:0000278=Reactome:REACT_152, GO:0006730=GO_REF:0000037, GO:0004146=PMID:21876184} P00374 Dihydrofolate reductase protein 20110817 {GO:0050661=IEA, GO:0050999=TAS, GO:0031427=IEA, GO:0006767=TAS, GO:0044281=TAS, GO:0005575=ND, GO:0003729=IDA, GO:0009165=NAS, GO:0005829=TAS, GO:0000082=TAS, GO:0000083=TAS, GO:0006766=TAS, GO:0008144=IDA, GO:0046653=IDA, GO:0046654=IEA, GO:0046655=TAS, GO:0046209=TAS, GO:0005654=TAS, GO:0006545=NAS, GO:0000278=TAS, GO:0006730=IEA, GO:0004146=IDA} G1/S transition of mitotic cell cycle, folic acid metabolic process, glycine biosynthetic process, mitotic cell cycle, nitric oxide metabolic process, nucleotide biosynthetic process, one-carbon metabolic process, regulation of nitric-oxide synthase activity, regulation of transcription involved in G1/S phase of mitotic cell cycle, response to methotrexate, small molecule metabolic process, tetrahydrofolate biosynthetic process, tetrahydrofolate metabolic process, vitamin metabolic process, water-soluble vitamin metabolic process cellular_component, cytosol, nucleoplasm NADP binding, dihydrofolate reductase activity, drug binding, mRNA binding Human DHFRL1 UniProtKB UniProtKB {GO:0005739=PMID:21876184, GO:0050661=GO_REF:0000002, GO:0005759=PMID:21876188, GO:0005743=PMID:21876188, GO:0046653=PMID:21876184, GO:0046654=GO_REF:0000041, GO:0046105=PMID:21876188, GO:0006545=GO_REF:0000002, GO:0003729=PMID:21876184, GO:0006730=GO_REF:0000037, GO:0009165=GO_REF:0000002, GO:0004146=PMID:21876188} Q86XF0 Dihydrofolate reductase, mitochondrial protein 20110916 {GO:0005739=IDA, GO:0050661=IEA, GO:0005759=IMP, GO:0005743=IMP, GO:0046653=IDA, GO:0046654=IEA, GO:0046105=IDA, GO:0006545=IEA, GO:0003729=IDA, GO:0006730=IEA, GO:0009165=IEA, GO:0004146=IMP} glycine biosynthetic process, nucleotide biosynthetic process, one-carbon metabolic process, tetrahydrofolate biosynthetic process, tetrahydrofolate metabolic process, thymidine biosynthetic process mitochondrial inner membrane, mitochondrial matrix, mitochondrion NADP binding, dihydrofolate reductase activity, mRNA binding Human DHH BHF-UCL UniProtKB {GO:0005515=PMID:19561611, GO:0005886=GO_REF:0000039, GO:0005509=PMID:19561611, GO:0007267=GO_REF:0000002, GO:0007286=GO_REF:0000019, GO:0050810=GO_REF:0000019, GO:0022402=GO_REF:0000019, GO:0005615=GO_REF:0000039, GO:0005113=GO_REF:0000019, GO:0030238=GO_REF:0000019, GO:0006508=GO_REF:0000037, GO:0033327=GO_REF:0000019, GO:0008233=GO_REF:0000037, GO:0008270=PMID:19561611} O43323 Desert hedgehog protein protein 20110727 {GO:0005515=IPI, GO:0005886=IEA, GO:0005509=IDA, GO:0007267=IEA, GO:0007286=IEA, GO:0050810=IEA, GO:0022402=IEA, GO:0005615=IEA, GO:0005113=IEA, GO:0030238=IEA, GO:0006508=IEA, GO:0033327=IEA, GO:0008233=IEA, GO:0008270=IDA} Leydig cell differentiation, cell cycle process, cell-cell signaling, male sex determination, proteolysis, regulation of steroid biosynthetic process, spermatid development extracellular space, plasma membrane calcium ion binding, patched binding, peptidase activity, protein binding, zinc ion binding Human UniProtKB:Q96QV1 DHODH Reactome UniProtKB {GO:0048039=GO_REF:0000019, GO:0007565=GO_REF:0000019, GO:0043065=GO_REF:0000019, GO:0044205=GO_REF:0000041, GO:0010181=GO_REF:0000019, GO:0042493=GO_REF:0000019, GO:0005743=Reactome:REACT_669, GO:0006222=GO_REF:0000002, GO:0055086=Reactome:REACT_1698, GO:0044281=Reactome:REACT_111217, GO:0090140=GO_REF:0000019, GO:0031000=GO_REF:0000019, GO:0042594=GO_REF:0000019, GO:0046134=Reactome:REACT_21376, GO:0016020=GO_REF:0000002, GO:0007595=GO_REF:0000019, GO:0008144=GO_REF:0000019, GO:0043025=GO_REF:0000019, GO:0004152=Reactome:REACT_669, GO:0016021=GO_REF:0000037, GO:0006207=GO_REF:0000029, GO:0006206=Reactome:REACT_957, GO:0004158=GO_REF:0000019} Q02127 Dihydroorotate dehydrogenase (quinone), mitochondrial protein 20130213 {GO:0048039=IEA, GO:0007565=IEA, GO:0043065=IEA, GO:0044205=IEA, GO:0010181=IEA, GO:0042493=IEA, GO:0005743=TAS, GO:0006222=IEA, GO:0055086=TAS, GO:0044281=TAS, GO:0090140=IEA, GO:0031000=IEA, GO:0042594=IEA, GO:0046134=TAS, GO:0016020=IEA, GO:0007595=IEA, GO:0008144=IEA, GO:0043025=IEA, GO:0004152=TAS, GO:0016021=IEA, GO:0006207=NAS, GO:0006206=TAS, GO:0004158=IEA} 'de novo' UMP biosynthetic process, 'de novo' pyrimidine nucleobase biosynthetic process, UMP biosynthetic process, female pregnancy, lactation, nucleobase-containing small molecule metabolic process, positive regulation of apoptotic process, pyrimidine nucleobase metabolic process, pyrimidine nucleoside biosynthetic process, regulation of mitochondrial fission, response to caffeine, response to drug, response to starvation, small molecule metabolic process integral to membrane, membrane, mitochondrial inner membrane, neuronal cell body FMN binding, dihydroorotate dehydrogenase activity, dihydroorotate oxidase activity, drug binding, ubiquinone binding Human DHPS InterPro UniProtKB {GO:0005515=PMID:19060904, GO:0008284=PMID:8549832, GO:0008612=GO_REF:0000002, GO:0051289=GO_REF:0000019, GO:0050983=GO_REF:0000003, GO:0044267=Reactome:REACT_17015, GO:0006412=PMID:7673224, GO:0043687=Reactome:REACT_22161, GO:0034038=Reactome:REACT_12551, GO:0005829=Reactome:REACT_12551} Q5J8M5 Migration-inducing gene 13 protein 20130413 {GO:0005515=IPI, GO:0008284=TAS, GO:0008612=IEA, GO:0051289=IEA, GO:0050983=IEA, GO:0044267=TAS, GO:0006412=TAS, GO:0043687=TAS, GO:0034038=TAS, GO:0005829=TAS} cellular protein metabolic process, deoxyhypusine biosynthetic process from spermidine, peptidyl-lysine modification to hypusine, positive regulation of cell proliferation, post-translational protein modification, protein homotetramerization, translation cytosol deoxyhypusine synthase activity, protein binding Human InterPro:IPR002773 DHRS1 LIFEdb UniProtKB {GO:0005783=GO_REF:0000054, GO:0005743=GO_REF:0000019, GO:0016491=GO_REF:0000037} Q96LJ7 Dehydrogenase/reductase SDR family member 1 protein 20100607 {GO:0005783=IDA, GO:0005743=IEA, GO:0016491=IEA} endoplasmic reticulum, mitochondrial inner membrane oxidoreductase activity Human DHRS12 UniProtKB UniProtKB {GO:0016491=GO_REF:0000037} A0PJE2 Dehydrogenase/reductase SDR family member 12 protein 20130413 {GO:0016491=IEA} oxidoreductase activity Human UniProtKB-KW:KW-0560 DHRS13 UniProtKB UniProtKB {GO:0016491=GO_REF:0000037, GO:0005576=GO_REF:0000039} Q6UX07 Dehydrogenase/reductase SDR family member 13 protein 20130413 {GO:0016491=IEA, GO:0005576=IEA} extracellular region oxidoreductase activity Human UniProtKB-SubCell:SL-0243 DHRS2 UniProtKB UniProtKB {GO:0043066=PMID:19443906, GO:0008285=PMID:1847869, GO:0004090=PMID:16685466, GO:0009636=PMID:16685466, GO:0005634=PMID:1847869, GO:0005635=PMID:11997086, GO:0005739=PMID:19443906, GO:0005737=PMID:11944995, GO:0016491=GO_REF:0000002, GO:0008207=PMID:7556196, GO:0034599=PMID:19443906, GO:0043011=PMID:11944995, GO:0055114=PMID:16685466} Q13268 Dehydrogenase/reductase SDR family member 2 protein 20080207 {GO:0043066=IMP, GO:0008285=NAS, GO:0004090=IDA, GO:0009636=IDA, GO:0005634=IDA, GO:0005635=IDA, GO:0005739=IDA, GO:0005737=IDA, GO:0016491=IEA, GO:0008207=NAS, GO:0034599=IDA, GO:0043011=IEP, GO:0055114=IDA} C21-steroid hormone metabolic process, cellular response to oxidative stress, myeloid dendritic cell differentiation, negative regulation of apoptotic process, negative regulation of cell proliferation, oxidation-reduction process, response to toxic substance cytoplasm, mitochondrion, nuclear envelope, nucleus carbonyl reductase (NADPH) activity, oxidoreductase activity Human DHRS3 InterPro UniProtKB {GO:0007603=Reactome:REACT_160125, GO:0000166=PMID:9705317, GO:0042622=Reactome:REACT_160119, GO:0042572=PMID:9705317, GO:0016491=GO_REF:0000002, GO:0009055=PMID:9705317, GO:0016021=GO_REF:0000037, GO:0052650=GO_REF:0000003, GO:0001523=Reactome:REACT_160083, GO:0007601=PMID:9705317} Q5SUY4 Short-chain dehydrogenase/reductase 3 protein 20130413 {GO:0007603=TAS, GO:0000166=TAS, GO:0042622=TAS, GO:0042572=TAS, GO:0016491=IEA, GO:0009055=TAS, GO:0016021=IEA, GO:0052650=IEA, GO:0001523=TAS, GO:0007601=TAS} phototransduction, visible light, retinoid metabolic process, retinol metabolic process, visual perception integral to membrane, photoreceptor outer segment membrane NADP-retinol dehydrogenase activity, electron carrier activity, nucleotide binding, oxidoreductase activity Human InterPro:IPR002198 DHRS4 UniProtKB UniProtKB {GO:0004090=PMID:18571493, GO:0051262=PMID:18571493, GO:0006066=PMID:18571493, GO:0005102=PMID:20178365, GO:0005634=GO_REF:0000039, GO:0005739=GO_REF:0000024, GO:0016491=GO_REF:0000002, GO:0018455=PMID:18571493, GO:0042180=PMID:18571493, GO:0008202=PMID:18571493, GO:0005778=PMID:10333503, GO:0000253=PMID:19056333, GO:0005777=PMID:17230527, GO:0055114=PMID:19442656} Q9BTZ2 Dehydrogenase/reductase SDR family member 4 protein 20120427 {GO:0004090=IDA, GO:0051262=IDA, GO:0006066=IDA, GO:0005102=IPI, GO:0005634=IEA, GO:0005739=ISS, GO:0016491=IEA, GO:0018455=IDA, GO:0042180=IDA, GO:0008202=IDA, GO:0005778=IDA, GO:0000253=IDA, GO:0005777=IDA, GO:0055114=IDA} alcohol metabolic process, cellular ketone metabolic process, oxidation-reduction process, protein tetramerization, steroid metabolic process mitochondrion, nucleus, peroxisomal membrane, peroxisome "3-keto sterol reductase activity, alcohol dehydrogenase NAD(P)+"" activity, carbonyl reductase (NADPH) activity, oxidoreductase activity, receptor binding""" Human UniProtKB:P50542 DHRS4L1 UniProtKB UniProtKB {GO:0016491=GO_REF:0000037} P0CG22 Putative dehydrogenase/reductase SDR family member 4-like 2 protein 20130413 {GO:0016491=IEA} oxidoreductase activity Human UniProtKB-KW:KW-0560 DHRS4L2 UniProtKB UniProtKB {GO:0016491=GO_REF:0000037, GO:0005576=GO_REF:0000039} Q6PKH6 Dehydrogenase/reductase SDR family member 4-like 2 protein 20130413 {GO:0016491=IEA, GO:0005576=IEA} extracellular region oxidoreductase activity Human UniProtKB-SubCell:SL-0243 DHRS7 UniProtKB UniProtKB {GO:0016491=GO_REF:0000037} Q9Y394 Dehydrogenase/reductase SDR family member 7 protein 20130413 {GO:0016491=IEA} oxidoreductase activity Human UniProtKB-KW:KW-0560 DHRS7B UniProtKB UniProtKB {GO:0003674=GO_REF:0000015, GO:0008150=GO_REF:0000015, GO:0016491=GO_REF:0000037, GO:0005575=GO_REF:0000015, GO:0016021=GO_REF:0000037, GO:0005778=GO_REF:0000039} Q6IAN0 Dehydrogenase/reductase SDR family member 7B protein 20120517 {GO:0003674=ND, GO:0008150=ND, GO:0016491=IEA, GO:0005575=ND, GO:0016021=IEA, GO:0005778=IEA} biological_process cellular_component, integral to membrane, peroxisomal membrane molecular_function, oxidoreductase activity Human DHRSX UniProtKB UniProtKB {GO:0016491=GO_REF:0000037} Q8N5I4 Dehydrogenase/reductase SDR family member on chromosome X protein 20130413 {GO:0016491=IEA} oxidoreductase activity Human UniProtKB-KW:KW-0560 DHX15 HPA UniProtKB {GO:0008380=PMID:15146077, GO:0006397=GO_REF:0000037, GO:0008026=GO_REF:0000002, GO:0003724=PMID:7935475, GO:0005730=GO_REF:0000039, GO:0005634=GO_REF:0000052, GO:0003676=GO_REF:0000002, GO:0005524=GO_REF:0000037, GO:0005689=PMID:15146077} O43143 Putative pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15 protein 20120912 {GO:0008380=IC, GO:0006397=IEA, GO:0008026=IEA, GO:0003724=TAS, GO:0005730=IEA, GO:0005634=IDA, GO:0003676=IEA, GO:0005524=IEA, GO:0005689=IDA} RNA splicing, mRNA processing U12-type spliceosomal complex, nucleolus, nucleus ATP binding, ATP-dependent helicase activity, RNA helicase activity, nucleic acid binding Human DHX16 InterPro UniProtKB {GO:0008380=GO_REF:0000037, GO:0006397=GO_REF:0000037, GO:0008026=GO_REF:0000002, GO:0003724=PMID:9547260, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0003676=GO_REF:0000002, GO:0005524=GO_REF:0000002} Q5SQH5 DEAH (Asp-Glu-Ala-His) box polypeptide 16, isoform CRA_a protein 20130413 {GO:0008380=IEA, GO:0006397=IEA, GO:0008026=IEA, GO:0003724=TAS, GO:0005730=IDA, GO:0005634=IDA, GO:0003676=IEA, GO:0005524=IEA} RNA splicing, mRNA processing nucleolus, nucleus ATP binding, ATP-dependent helicase activity, RNA helicase activity, nucleic acid binding Human InterPro:IPR002464 DHX29 ENSEMBL UniProtKB {GO:0005739=GO_REF:0000019, GO:0008026=GO_REF:0000002, GO:0003743=GO_REF:0000037, GO:0005524=GO_REF:0000037} Q7Z478 ATP-dependent RNA helicase DHX29 protein 20130413 {GO:0005739=IEA, GO:0008026=IEA, GO:0003743=IEA, GO:0005524=IEA} mitochondrion ATP binding, ATP-dependent helicase activity, translation initiation factor activity Human Ensembl:ENSMUSP00000035244 DHX30 HPA UniProtKB {GO:0005739=GO_REF:0000052, GO:0042645=PMID:18063578, GO:0005515=PMID:23455922, GO:0008026=GO_REF:0000002, GO:0005737=GO_REF:0000052, GO:0003682=PMID:18063578, GO:0003723=GO_REF:0000037, GO:0003676=GO_REF:0000002, GO:0005524=GO_REF:0000037} Q7L2E3 Putative ATP-dependent RNA helicase DHX30 protein 20101115 {GO:0005739=IDA, GO:0042645=IDA, GO:0005515=IPI, GO:0008026=IEA, GO:0005737=IDA, GO:0003682=IDA, GO:0003723=IEA, GO:0003676=IEA, GO:0005524=IEA} cytoplasm, mitochondrial nucleoid, mitochondrion ATP binding, ATP-dependent helicase activity, RNA binding, chromatin binding, nucleic acid binding, protein binding Human DHX32 UniProtKB UniProtKB {GO:0005739=GO_REF:0000039, GO:0004386=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0005524=GO_REF:0000037} Q7L7V1 Putative pre-mRNA-splicing factor ATP-dependent RNA helicase DHX32 protein 20130413 {GO:0005739=IEA, GO:0004386=IEA, GO:0005634=IEA, GO:0005524=IEA} mitochondrion, nucleus ATP binding, helicase activity Human UniProtKB-SubCell:SL-0173 DHX33 UniProtKB UniProtKB {GO:0008026=GO_REF:0000002, GO:0045943=PMID:21930779, GO:0000182=PMID:21930779, GO:0005730=PMID:21930779, GO:0004386=GO_REF:0000002, GO:0005654=PMID:21930779, GO:0033613=GO_REF:0000019, GO:0003676=GO_REF:0000002, GO:0005524=GO_REF:0000037} Q9H6R0 Putative ATP-dependent RNA helicase DHX33 protein 20120109 {GO:0008026=IEA, GO:0045943=IDA, GO:0000182=IDA, GO:0005730=IDA, GO:0004386=IEA, GO:0005654=IDA, GO:0033613=IEA, GO:0003676=IEA, GO:0005524=IEA} positive regulation of transcription from RNA polymerase I promoter nucleolus, nucleoplasm ATP binding, ATP-dependent helicase activity, activating transcription factor binding, helicase activity, nucleic acid binding, rDNA binding Human DHX34 UniProtKB UniProtKB {GO:0008026=GO_REF:0000002, GO:0003723=GO_REF:0000037, GO:0003676=GO_REF:0000002, GO:0005524=GO_REF:0000037} Q14147 Probable ATP-dependent RNA helicase DHX34 protein 20130413 {GO:0008026=IEA, GO:0003723=IEA, GO:0003676=IEA, GO:0005524=IEA} ATP binding, ATP-dependent helicase activity, RNA binding, nucleic acid binding Human UniProtKB-KW:KW-0067 DHX35 UniProtKB UniProtKB {GO:0008026=GO_REF:0000002, GO:0000398=PMID:11991638, GO:0071013=PMID:11991638, GO:0003676=GO_REF:0000002, GO:0005524=GO_REF:0000037} Q9H5Z1 Probable ATP-dependent RNA helicase DHX35 protein 20110302 {GO:0008026=IEA, GO:0000398=IC, GO:0071013=IDA, GO:0003676=IEA, GO:0005524=IEA} mRNA splicing, via spliceosome catalytic step 2 spliceosome ATP binding, ATP-dependent helicase activity, nucleic acid binding Human DHX36 HPA UniProtKB {GO:0005515=PMID:17932509, GO:0003725=GO_REF:0000019, GO:0008026=GO_REF:0000002, GO:0005737=GO_REF:0000052, GO:0004386=GO_REF:0000002, GO:0005634=GO_REF:0000052, GO:0003676=GO_REF:0000002, GO:0009615=GO_REF:0000019, GO:0043330=GO_REF:0000019, GO:0005524=GO_REF:0000037} Q9H2U1 Probable ATP-dependent RNA helicase DHX36 protein 20101115 {GO:0005515=IPI, GO:0003725=IEA, GO:0008026=IEA, GO:0005737=IDA, GO:0004386=IEA, GO:0005634=IDA, GO:0003676=IEA, GO:0009615=IEA, GO:0043330=IEA, GO:0005524=IEA} response to exogenous dsRNA, response to virus cytoplasm, nucleus ATP binding, ATP-dependent helicase activity, double-stranded RNA binding, helicase activity, nucleic acid binding, protein binding Human DHX37 UniProtKB UniProtKB {GO:0008026=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0005524=GO_REF:0000037} Q8IY37 Probable ATP-dependent RNA helicase DHX37 protein 20130413 {GO:0008026=IEA, GO:0003676=IEA, GO:0005524=IEA} ATP binding, ATP-dependent helicase activity, nucleic acid binding Human UniProtKB-KW:KW-0067 DHX38 Reactome UniProtKB {GO:0008026=GO_REF:0000002, GO:0008380=Reactome:REACT_1735, GO:0006369=Reactome:REACT_894, GO:0010467=Reactome:REACT_71, GO:0006366=Reactome:REACT_1366, GO:0031124=Reactome:REACT_1849, GO:0004386=GO_REF:0000038, GO:0005634=PMID:9524131, GO:0003676=GO_REF:0000002, GO:0071013=PMID:11991638, GO:0005524=GO_REF:0000037, GO:0006406=Reactome:REACT_1597, GO:0000398=Reactome:REACT_467, GO:0005654=Reactome:REACT_1935} Q92620 Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP16 protein 20130213 {GO:0008026=IEA, GO:0008380=TAS, GO:0006369=TAS, GO:0010467=TAS, GO:0006366=TAS, GO:0031124=TAS, GO:0004386=IEA, GO:0005634=NAS, GO:0003676=IEA, GO:0071013=IDA, GO:0005524=IEA, GO:0006406=TAS, GO:0000398=TAS, GO:0005654=TAS} RNA splicing, gene expression, mRNA 3'-end processing, mRNA export from nucleus, mRNA splicing, via spliceosome, termination of RNA polymerase II transcription, transcription from RNA polymerase II promoter catalytic step 2 spliceosome, nucleoplasm, nucleus ATP binding, ATP-dependent helicase activity, helicase activity, nucleic acid binding Human DHX40 UniProtKB UniProtKB {GO:0005622=GO_REF:0000002, GO:0008026=GO_REF:0000002, GO:0006810=GO_REF:0000002, GO:0004386=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0005524=GO_REF:0000037} Q8IX18 Probable ATP-dependent RNA helicase DHX40 protein 20130413 {GO:0005622=IEA, GO:0008026=IEA, GO:0006810=IEA, GO:0004386=IEA, GO:0003676=IEA, GO:0005524=IEA} transport intracellular ATP binding, ATP-dependent helicase activity, helicase activity, nucleic acid binding Human UniProtKB-KW:KW-0067 DHX57 UniProtKB UniProtKB {GO:0008026=GO_REF:0000002, GO:0004386=GO_REF:0000002, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0005524=GO_REF:0000037} Q6P158 Putative ATP-dependent RNA helicase DHX57 protein 20130413 {GO:0008026=IEA, GO:0004386=IEA, GO:0008270=IEA, GO:0003676=IEA, GO:0005524=IEA} ATP binding, ATP-dependent helicase activity, helicase activity, nucleic acid binding, zinc ion binding Human UniProtKB-KW:KW-0067 DHX58 HPA UniProtKB {GO:0003725=PMID:18411269, GO:0005515=PMID:21903422, GO:0003727=PMID:18411269, GO:0004386=GO_REF:0000037, GO:1900246=GO_REF:0000024, GO:0039534=PMID:21187438, GO:1900245=GO_REF:0000024, GO:0009615=GO_REF:0000024, GO:0003677=GO_REF:0000002, GO:0005524=GO_REF:0000037, GO:0051607=GO_REF:0000037, GO:0005737=GO_REF:0000052, GO:0016787=GO_REF:0000002, GO:0045087=GO_REF:0000037, GO:0019048=GO_REF:0000037, GO:0045088=PMID:18411269, GO:0039536=PMID:21187438, GO:0008270=PMID:19278996, GO:0032481=GO_REF:0000024, GO:0032480=PMID:21525357, GO:0045824=PMID:21525357} Q96C10 Probable ATP-dependent RNA helicase DHX58 protein 20100326 {GO:0003725=IDA, GO:0005515=IPI, GO:0003727=IDA, GO:0004386=IEA, GO:1900246=ISS, GO:0039534=IMP, GO:1900245=ISS, GO:0009615=ISS, GO:0003677=IEA, GO:0005524=IEA, GO:0051607=IEA, GO:0005737=IDA, GO:0016787=IEA, GO:0045087=IEA, GO:0019048=IEA, GO:0045088=IDA, GO:0039536=IMP, GO:0008270=IDA, GO:0032481=ISS, GO:0032480=IDA, GO:0045824=IDA} defense response to virus, innate immune response, negative regulation of MDA-5 signaling pathway, negative regulation of RIG-I signaling pathway, negative regulation of innate immune response, negative regulation of type I interferon production, positive regulation of MDA-5 signaling pathway, positive regulation of RIG-I signaling pathway, positive regulation of type I interferon production, regulation of innate immune response, response to virus, virus-host interaction cytoplasm ATP binding, DNA binding, double-stranded RNA binding, helicase activity, hydrolase activity, protein binding, single-stranded RNA binding, zinc ion binding Human DHX8 HPA UniProtKB {GO:0008380=PMID:7935475, GO:0004004=PMID:7935475, GO:0005515=PMID:16820410, GO:0008026=GO_REF:0000002, GO:0006396=PMID:7935475, GO:0000398=PMID:11991638, GO:0003723=GO_REF:0000002, GO:0005730=GO_REF:0000052, GO:0005681=PMID:7935475, GO:0005634=GO_REF:0000052, GO:0071013=PMID:11991638, GO:0005524=GO_REF:0000037} Q14562 ATP-dependent RNA helicase DHX8 protein 20120912 {GO:0008380=TAS, GO:0004004=TAS, GO:0005515=IPI, GO:0008026=IEA, GO:0006396=TAS, GO:0000398=IC, GO:0003723=IEA, GO:0005730=IDA, GO:0005681=TAS, GO:0005634=IDA, GO:0071013=IDA, GO:0005524=IEA} RNA processing, RNA splicing, mRNA splicing, via spliceosome catalytic step 2 spliceosome, nucleolus, nucleus, spliceosomal complex ATP binding, ATP-dependent RNA helicase activity, ATP-dependent helicase activity, RNA binding, protein binding NOT Human DHX9 BHF-UCL UniProtKB {GO:0008380=Reactome:REACT_1735, GO:0003725=GO_REF:0000002, GO:0005515=PMID:21903422, GO:0010467=Reactome:REACT_71, GO:0003724=PMID:8690889, GO:0005813=PMID:17498979, GO:0070934=PMID:19029303, GO:0005730=GO_REF:0000039, GO:0005634=PMID:17498979, GO:0003677=GO_REF:0000037, GO:0005524=GO_REF:0000037, GO:0004004=PMID:9111062, GO:0034605=GO_REF:0000019, GO:0005737=PMID:8690889, GO:0004003=PMID:9111062, GO:0000398=Reactome:REACT_467, GO:0030529=PMID:18809582, GO:0001085=PMID:17303075, GO:0007623=GO_REF:0000019, GO:0005654=Reactome:REACT_1935, GO:0070937=PMID:19029303} Q08211 ATP-dependent RNA helicase A protein 20111118 {GO:0008380=TAS, GO:0003725=IEA, GO:0005515=IPI, GO:0010467=TAS, GO:0003724=TAS, GO:0005813=IDA, GO:0070934=IMP, GO:0005730=IEA, GO:0005634=IDA, GO:0003677=IEA, GO:0005524=IEA, GO:0004004=TAS, GO:0034605=IEA, GO:0005737=TAS, GO:0004003=TAS, GO:0000398=TAS, GO:0030529=IDA, GO:0001085=IPI, GO:0007623=IEA, GO:0005654=TAS, GO:0070937=IDA} CRD-mediated mRNA stabilization, RNA splicing, cellular response to heat, circadian rhythm, gene expression, mRNA splicing, via spliceosome CRD-mediated mRNA stability complex, centrosome, cytoplasm, nucleolus, nucleoplasm, nucleus, ribonucleoprotein complex ATP binding, ATP-dependent DNA helicase activity, ATP-dependent RNA helicase activity, DNA binding, RNA helicase activity, RNA polymerase II transcription factor binding, double-stranded RNA binding, protein binding Human UniProtKB:Q8VI67 DIABLO HPA UniProtKB {GO:0005515=PMID:21185211, GO:0008625=PMID:10950947, GO:0035631=GO_REF:0000024, GO:0008635=PMID:10929711, GO:0006919=PMID:10972280, GO:0008631=GO_REF:0000019, GO:0006915=Reactome:REACT_578, GO:0006917=GO_REF:0000002, GO:0097193=Reactome:REACT_964, GO:0005829=Reactome:REACT_2102, GO:0005739=GO_REF:0000052, GO:0005758=Reactome:REACT_1101, GO:0009898=GO_REF:0000024} Q9NR28 Diablo homolog, mitochondrial protein 20080205 {GO:0005515=IPI, GO:0008625=TAS, GO:0035631=ISS, GO:0008635=TAS, GO:0006919=TAS, GO:0008631=IEA, GO:0006915=TAS, GO:0006917=IEA, GO:0097193=TAS, GO:0005829=TAS, GO:0005739=IDA, GO:0005758=TAS, GO:0009898=ISS} activation of cysteine-type endopeptidase activity involved in apoptotic process, activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c, apoptotic process, extrinsic apoptotic signaling pathway via death domain receptors, induction of apoptosis, intrinsic apoptotic signaling pathway, intrinsic apoptotic signaling pathway in response to oxidative stress CD40 receptor complex, cytosol, internal side of plasma membrane, mitochondrial intermembrane space, mitochondrion protein binding Human DIAPH1 BHF-UCL UniProtKB {GO:0005515=PMID:22190034, GO:0072686=PMID:15123714, GO:0043005=GO_REF:0000019, GO:0030036=GO_REF:0000002, GO:0007605=GO_REF:0000037, GO:0008360=PMID:21834987, GO:0051279=PMID:15123714, GO:0005102=PMID:9360932, GO:0032886=PMID:20937854, GO:0003779=GO_REF:0000019, GO:0032587=GO_REF:0000039, GO:0031175=GO_REF:0000019, GO:0044325=PMID:15123714, GO:0005737=GO_REF:0000037, GO:0007010=PMID:21834987, GO:0030041=GO_REF:0000019, GO:0017048=GO_REF:0000019, GO:0005522=GO_REF:0000019, GO:0071420=PMID:15123714} O60610 Protein diaphanous homolog 1 protein 20120116 {GO:0005515=IPI, GO:0072686=IDA, GO:0043005=IEA, GO:0030036=IEA, GO:0007605=IEA, GO:0008360=IMP, GO:0051279=IMP, GO:0005102=NAS, GO:0032886=IMP, GO:0003779=IEA, GO:0032587=IEA, GO:0031175=IEA, GO:0044325=IPI, GO:0005737=IEA, GO:0007010=IMP, GO:0030041=IEA, GO:0017048=IEA, GO:0005522=IEA, GO:0071420=IMP} actin cytoskeleton organization, actin filament polymerization, cellular response to histamine, cytoskeleton organization, neuron projection development, regulation of cell shape, regulation of microtubule-based process, regulation of release of sequestered calcium ion into cytosol, sensory perception of sound cytoplasm, mitotic spindle, neuron projection, ruffle membrane Rho GTPase binding, actin binding, ion channel binding, profilin binding, protein binding, receptor binding Human DIAPH2 HPA UniProtKB {GO:0030036=GO_REF:0000002, GO:0005794=GO_REF:0000052, GO:0048477=GO_REF:0000037, GO:0005102=PMID:9497258, GO:0005730=GO_REF:0000052, GO:0003779=GO_REF:0000019, GO:0007275=GO_REF:0000037, GO:0007292=PMID:9497258, GO:0030154=GO_REF:0000037, GO:0005829=GO_REF:0000039, GO:0043231=GO_REF:0000052, GO:0005739=GO_REF:0000052, GO:0000910=PMID:9497258, GO:0005737=GO_REF:0000052, GO:0030041=GO_REF:0000019, GO:0017048=GO_REF:0000002, GO:0005769=GO_REF:0000039} O60879 Protein diaphanous homolog 2 protein 20101115 {GO:0030036=IEA, GO:0005794=IDA, GO:0048477=IEA, GO:0005102=TAS, GO:0005730=IDA, GO:0003779=IEA, GO:0007275=IEA, GO:0007292=TAS, GO:0030154=IEA, GO:0005829=IEA, GO:0043231=IDA, GO:0005739=IDA, GO:0000910=TAS, GO:0005737=IDA, GO:0030041=IEA, GO:0017048=IEA, GO:0005769=IEA} actin cytoskeleton organization, actin filament polymerization, cell differentiation, cytokinesis, female gamete generation, multicellular organismal development, oogenesis Golgi apparatus, cytoplasm, cytosol, early endosome, intracellular membrane-bounded organelle, mitochondrion, nucleolus Rho GTPase binding, actin binding, receptor binding Human DIAPH3 UniProtKB UniProtKB {GO:0030036=GO_REF:0000002, GO:0017048=GO_REF:0000002, GO:0003779=GO_REF:0000002, GO:0005829=GO_REF:0000039} Q9NSV4 Protein diaphanous homolog 3 protein 20130413 {GO:0030036=IEA, GO:0017048=IEA, GO:0003779=IEA, GO:0005829=IEA} actin cytoskeleton organization cytosol Rho GTPase binding, actin binding Human UniProtKB-SubCell:SL-0091 DICER1 BHF-UCL UniProtKB {GO:0060576=GO_REF:0000019, GO:0005515=PMID:21903422, GO:0010467=Reactome:REACT_71, GO:0070173=GO_REF:0000019, GO:0045069=GO_REF:0000019, GO:0009791=GO_REF:0000019, GO:0048536=GO_REF:0000019, GO:0031069=GO_REF:0000019, GO:0016442=PMID:15973356, GO:0051607=GO_REF:0000019, GO:0004525=PMID:12560494, GO:0000122=GO_REF:0000024, GO:0021889=GO_REF:0000019, GO:0055013=GO_REF:0000019, GO:0003725=PMID:12411504, GO:0030423=PMID:17452327, GO:2000630=GO_REF:0000019, GO:0030422=PMID:17452327, GO:0021987=GO_REF:0000019, GO:0030324=GO_REF:0000019, GO:0003723=GO_REF:0000002, GO:0021675=GO_REF:0000024, GO:0046872=GO_REF:0000037, GO:0005829=Reactome:REACT_118784, GO:0071335=GO_REF:0000019, GO:0035264=GO_REF:0000019, GO:0045944=GO_REF:0000019, GO:0031054=PMID:15973356, GO:0051726=GO_REF:0000019, GO:0031643=GO_REF:0000024, GO:0008026=GO_REF:0000002, GO:0006396=GO_REF:0000002, GO:0043066=GO_REF:0000019, GO:0021522=GO_REF:0000019, GO:0014040=GO_REF:0000024, GO:0006915=GO_REF:0000019, GO:0060119=GO_REF:0000019, GO:0001525=GO_REF:0000019, GO:0010070=GO_REF:0000019, GO:0051225=GO_REF:0000019, GO:0005524=GO_REF:0000037, GO:0048713=GO_REF:0000019, GO:0010626=GO_REF:0000024, GO:0035198=GO_REF:0000019, GO:0035196=GO_REF:0000024, GO:0019827=GO_REF:0000019, GO:0048812=GO_REF:0000024, GO:0045664=GO_REF:0000019, GO:0032290=GO_REF:0000024, GO:0035116=GO_REF:0000019, GO:0048754=GO_REF:0000019} Q9UPY3 Endoribonuclease Dicer protein 20110316 {GO:0060576=IEA, GO:0005515=IPI, GO:0010467=TAS, GO:0070173=IEA, GO:0045069=IEA, GO:0009791=IEA, GO:0048536=IEA, GO:0031069=IEA, GO:0016442=IDA, GO:0051607=IEA, GO:0004525=IDA, GO:0000122=ISS, GO:0021889=IEA, GO:0055013=IEA, GO:0003725=IDA, GO:0030423=IMP, GO:2000630=IEA, GO:0030422=IDA, GO:0021987=IEA, GO:0030324=IEA, GO:0003723=IEA, GO:0021675=ISS, GO:0046872=IEA, GO:0005829=TAS, GO:0071335=IEA, GO:0035264=IEA, GO:0045944=IEA, GO:0031054=IDA, GO:0051726=IEA, GO:0031643=ISS, GO:0008026=IEA, GO:0006396=IEA, GO:0043066=IEA, GO:0021522=IEA, GO:0014040=ISS, GO:0006915=IEA, GO:0060119=IEA, GO:0001525=IEA, GO:0010070=IEA, GO:0051225=IEA, GO:0005524=IEA, GO:0048713=IEA, GO:0010626=ISS, GO:0035198=IEA, GO:0035196=ISS, GO:0019827=IEA, GO:0048812=ISS, GO:0045664=IEA, GO:0032290=ISS, GO:0035116=IEA, GO:0048754=IEA} RNA processing, angiogenesis, apoptotic process, branching morphogenesis of an epithelial tube, cardiac muscle cell development, cerebral cortex development, defense response to virus, embryonic hindlimb morphogenesis, gene expression, hair follicle cell proliferation, hair follicle morphogenesis, inner ear receptor cell development, intestinal epithelial cell development, lung development, multicellular organism growth, negative regulation of Schwann cell proliferation, negative regulation of apoptotic process, negative regulation of transcription from RNA polymerase II promoter, nerve development, neuron projection morphogenesis, olfactory bulb interneuron differentiation, peripheral nervous system myelin formation, positive regulation of Schwann cell differentiation, positive regulation of miRNA metabolic process, positive regulation of myelination, positive regulation of transcription from RNA polymerase II promoter, post-embryonic development, pre-miRNA processing, production of miRNAs involved in gene silencing by miRNA, production of siRNA involved in RNA interference, regulation of cell cycle, regulation of enamel mineralization, regulation of neuron differentiation, regulation of oligodendrocyte differentiation, regulation of viral genome replication, spinal cord motor neuron differentiation, spindle assembly, spleen development, stem cell maintenance, targeting of mRNA for destruction involved in RNA interference, zygote asymmetric cell division RNA-induced silencing complex, cytosol ATP binding, ATP-dependent helicase activity, RNA binding, double-stranded RNA binding, metal ion binding, miRNA binding, protein binding, ribonuclease III activity Human UniProtKB:Q4G034 DIDO1 UniProtKB UniProtKB {GO:0005737=GO_REF:0000039, GO:0006915=GO_REF:0000019, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0006351=GO_REF:0000002} Q9BTC0 Death-inducer obliterator 1 protein 20130413 {GO:0005737=IEA, GO:0006915=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0006351=IEA} apoptotic process, transcription, DNA-dependent cytoplasm, nucleus zinc ion binding Human UniProtKB-SubCell:SL-0086 DIEXF UniProtKB UniProtKB {GO:0005730=GO_REF:0000039, GO:0007275=GO_REF:0000037, GO:0005634=GO_REF:0000038} Q68CQ4 Digestive organ expansion factor homolog protein 20130413 {GO:0005730=IEA, GO:0007275=IEA, GO:0005634=IEA} multicellular organismal development nucleolus, nucleus Human UniProtKB-SubCell:SL-0188 DIMT1 UniProtKB UniProtKB {GO:0003723=GO_REF:0000037, GO:0005730=GO_REF:0000039, GO:0052909=GO_REF:0000003, GO:0000179=GO_REF:0000002} Q9UNQ2 Probable dimethyladenosine transferase protein 20130413 {GO:0003723=IEA, GO:0005730=IEA, GO:0052909=IEA, GO:0000179=IEA} nucleolus 18S rRNA (adenine(1779)-N(6)/adenine(1780)-N(6))-dimethyltransferase activity, RNA binding, rRNA (adenine-N6,N6-)-dimethyltransferase activity Human UniProtKB-SubCell:SL-0188 DIO1 Reactome UniProtKB {GO:0034641=Reactome:REACT_13, GO:0008430=GO_REF:0000019, GO:0005886=Reactome:REACT_15469, GO:0005789=GO_REF:0000039, GO:0042446=GO_REF:0000037, GO:0004800=GO_REF:0000003, GO:0006590=Reactome:REACT_15292, GO:0044281=Reactome:REACT_111217, GO:0016021=GO_REF:0000037} P49895 Type I iodothyronine deiodinase protein 20130114 {GO:0034641=TAS, GO:0008430=IEA, GO:0005886=TAS, GO:0005789=IEA, GO:0042446=IEA, GO:0004800=IEA, GO:0006590=TAS, GO:0044281=TAS, GO:0016021=IEA} cellular nitrogen compound metabolic process, hormone biosynthetic process, small molecule metabolic process, thyroid hormone generation endoplasmic reticulum membrane, integral to membrane, plasma membrane selenium binding, thyroxine 5'-deiodinase activity Human DIO2 Reactome UniProtKB {GO:0005886=Reactome:REACT_15469, GO:0004800=PMID:19651899, GO:0044281=Reactome:REACT_111217, GO:0042403=PMID:19651899, GO:0034641=Reactome:REACT_13, GO:0008430=PMID:9837913, GO:0016020=PMID:9837913, GO:0001514=PMID:9837913, GO:0042446=GO_REF:0000037, GO:0006590=Reactome:REACT_15292, GO:0016021=GO_REF:0000037, GO:0042404=GO_REF:0000019, GO:0031625=PMID:19651899} Q92813 Type II iodothyronine deiodinase protein 20130114 {GO:0005886=TAS, GO:0004800=IDA, GO:0044281=TAS, GO:0042403=IDA, GO:0034641=TAS, GO:0008430=IC, GO:0016020=IC, GO:0001514=NAS, GO:0042446=IEA, GO:0006590=TAS, GO:0016021=IEA, GO:0042404=IEA, GO:0031625=IPI} cellular nitrogen compound metabolic process, hormone biosynthetic process, selenocysteine incorporation, small molecule metabolic process, thyroid hormone catabolic process, thyroid hormone generation, thyroid hormone metabolic process integral to membrane, membrane, plasma membrane selenium binding, thyroxine 5'-deiodinase activity, ubiquitin protein ligase binding Human DIO3 Reactome UniProtKB {GO:0034641=Reactome:REACT_13, GO:0008150=GO_REF:0000015, GO:0005886=Reactome:REACT_15528, GO:0004800=PMID:7593630, GO:0042446=GO_REF:0000037, GO:0006590=Reactome:REACT_15292, GO:0044281=Reactome:REACT_111217, GO:0016021=GO_REF:0000037, GO:0033798=GO_REF:0000003, GO:0010008=GO_REF:0000039} P55073 Type III iodothyronine deiodinase protein 20130301 {GO:0034641=TAS, GO:0008150=ND, GO:0005886=TAS, GO:0004800=NAS, GO:0042446=IEA, GO:0006590=TAS, GO:0044281=TAS, GO:0016021=IEA, GO:0033798=IEA, GO:0010008=IEA} biological_process, cellular nitrogen compound metabolic process, hormone biosynthetic process, small molecule metabolic process, thyroid hormone generation endosome membrane, integral to membrane, plasma membrane thyroxine 5'-deiodinase activity, thyroxine 5-deiodinase activity Human DIP2A IntAct UniProtKB {GO:0005515=PMID:20054002, GO:0007275=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0003824=GO_REF:0000002, GO:0008134=GO_REF:0000002} Q14689 Disco-interacting protein 2 homolog A protein 20130415 {GO:0005515=IPI, GO:0007275=IEA, GO:0005634=IEA, GO:0003824=IEA, GO:0008134=IEA} multicellular organismal development nucleus catalytic activity, protein binding, transcription factor binding Human UniProtKB:Q62356 DIP2B InterPro UniProtKB {GO:0005634=GO_REF:0000002, GO:0003824=GO_REF:0000002, GO:0008134=GO_REF:0000002} Q9P265 Disco-interacting protein 2 homolog B protein 20130413 {GO:0005634=IEA, GO:0003824=IEA, GO:0008134=IEA} nucleus catalytic activity, transcription factor binding Human InterPro:IPR010506 DIP2C InterPro UniProtKB {GO:0005634=GO_REF:0000002, GO:0003824=GO_REF:0000002, GO:0008134=GO_REF:0000002} Q9Y2E4 Disco-interacting protein 2 homolog C protein 20130413 {GO:0005634=IEA, GO:0003824=IEA, GO:0008134=IEA} nucleus catalytic activity, transcription factor binding Human InterPro:IPR010506 DIRAS1 UniProtKB UniProtKB {GO:0005886=GO_REF:0000039, GO:0016020=GO_REF:0000002, GO:0007264=GO_REF:0000002, GO:0003924=GO_REF:0000002, GO:0005525=GO_REF:0000037} O95057 GTP-binding protein Di-Ras1 protein 20130413 {GO:0005886=IEA, GO:0016020=IEA, GO:0007264=IEA, GO:0003924=IEA, GO:0005525=IEA} small GTPase mediated signal transduction membrane, plasma membrane GTP binding, GTPase activity Human UniProtKB-SubCell:SL-0039 DIRAS2 UniProtKB UniProtKB {GO:0005886=GO_REF:0000039, GO:0007264=GO_REF:0000002, GO:0003924=GO_REF:0000002, GO:0005525=GO_REF:0000037} Q96HU8 GTP-binding protein Di-Ras2 protein 20130413 {GO:0005886=IEA, GO:0007264=IEA, GO:0003924=IEA, GO:0005525=IEA} small GTPase mediated signal transduction plasma membrane GTP binding, GTPase activity Human UniProtKB-SubCell:SL-0039 DIS3 IntAct UniProtKB {GO:0005515=PMID:21255825, GO:0010467=Reactome:REACT_71, GO:0016075=PMID:20368444, GO:0016070=Reactome:REACT_21257, GO:0016071=Reactome:REACT_20605, GO:0003723=GO_REF:0000037, GO:0006364=PMID:9562621, GO:0005730=PMID:20531386, GO:0043928=Reactome:REACT_20619, GO:0004540=GO_REF:0000002, GO:0071034=PMID:19056938, GO:0000178=PMID:9562621, GO:0005829=Reactome:REACT_25297, GO:0005085=PMID:9562621, GO:0004519=PMID:20531386, GO:0000175=PMID:20531386, GO:0000176=PMID:20531386, GO:0005654=PMID:20531389, GO:0000288=Reactome:REACT_20639} Q9Y2L1 Exosome complex exonuclease RRP44 protein 20130415 {GO:0005515=IPI, GO:0010467=TAS, GO:0016075=IMP, GO:0016070=TAS, GO:0016071=TAS, GO:0003723=IEA, GO:0006364=TAS, GO:0005730=IDA, GO:0043928=TAS, GO:0004540=IEA, GO:0071034=IMP, GO:0000178=TAS, GO:0005829=TAS, GO:0005085=IDA, GO:0004519=IMP, GO:0000175=IMP, GO:0000176=IDA, GO:0005654=IDA, GO:0000288=TAS} CUT catabolic process, RNA metabolic process, exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay, gene expression, mRNA metabolic process, nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay, rRNA catabolic process, rRNA processing cytosol, exosome (RNase complex), nuclear exosome (RNase complex), nucleolus, nucleoplasm 3'-5'-exoribonuclease activity, RNA binding, endonuclease activity, guanyl-nucleotide exchange factor activity, protein binding, ribonuclease activity Human UniProtKB:Q9NQT5 DIS3L HPA UniProtKB {GO:0016075=PMID:20531389, GO:0005813=GO_REF:0000052, GO:0005737=GO_REF:0000052, GO:0000175=PMID:20531386, GO:0005886=GO_REF:0000052, GO:0000177=PMID:20531386, GO:0003723=GO_REF:0000037, GO:0019899=PMID:20531386} Q8TF46 DIS3-like exonuclease 1 protein 20110516 {GO:0016075=IDA, GO:0005813=IDA, GO:0005737=IDA, GO:0000175=IMP, GO:0005886=IDA, GO:0000177=IDA, GO:0003723=IEA, GO:0019899=IPI} rRNA catabolic process centrosome, cytoplasm, cytoplasmic exosome (RNase complex), plasma membrane 3'-5'-exoribonuclease activity, RNA binding, enzyme binding Human DIS3L2 UniProtKB UniProtKB {GO:0005737=PMID:22306653, GO:0051306=PMID:22306653, GO:0007067=PMID:22306653, GO:0004527=GO_REF:0000037, GO:0008285=PMID:22306653, GO:0003723=GO_REF:0000037, GO:0004540=PMID:22306653, GO:0051301=GO_REF:0000037} Q8IYB7 DIS3-like exonuclease 2 protein 20120413 {GO:0005737=IDA, GO:0051306=IMP, GO:0007067=IMP, GO:0004527=IEA, GO:0008285=IMP, GO:0003723=IEA, GO:0004540=IDA, GO:0051301=IEA} cell division, mitosis, mitotic sister chromatid separation, negative regulation of cell proliferation cytoplasm RNA binding, exonuclease activity, ribonuclease activity Human DISC1 IntAct UniProtKB {GO:0005515=PMID:17043677, GO:0031929=GO_REF:0000019, GO:0021846=GO_REF:0000019, GO:0005813=PMID:18955030, GO:0030054=GO_REF:0000037, GO:0090128=GO_REF:0000019, GO:0005886=GO_REF:0000037, GO:0005874=GO_REF:0000037, GO:0030177=PMID:19303846, GO:0002052=PMID:19303846, GO:0000226=PMID:18955030, GO:0014069=GO_REF:0000039, GO:0005739=PMID:20880836, GO:2000060=GO_REF:0000019, GO:0045211=GO_REF:0000037, GO:0010975=GO_REF:0000019, GO:0051560=GO_REF:0000019, GO:0021799=GO_REF:0000019, GO:0001764=PMID:19502360, GO:0060070=GO_REF:0000019} Q9NRI5 Disrupted in schizophrenia 1 protein protein 20130415 {GO:0005515=IPI, GO:0031929=IEA, GO:0021846=IEA, GO:0005813=IDA, GO:0030054=IEA, GO:0090128=IEA, GO:0005886=IEA, GO:0005874=IEA, GO:0030177=IGI, GO:0002052=IGI, GO:0000226=IMP, GO:0014069=IEA, GO:0005739=IDA, GO:2000060=IEA, GO:0045211=IEA, GO:0010975=IEA, GO:0051560=IEA, GO:0021799=IEA, GO:0001764=IMP, GO:0060070=IEA} TOR signaling cascade, canonical Wnt receptor signaling pathway, cell proliferation in forebrain, cerebral cortex radially oriented cell migration, microtubule cytoskeleton organization, mitochondrial calcium ion homeostasis, neuron migration, positive regulation of Wnt receptor signaling pathway, positive regulation of neuroblast proliferation, positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process, regulation of neuron projection development, regulation of synapse maturation cell junction, centrosome, microtubule, mitochondrion, plasma membrane, postsynaptic density, postsynaptic membrane protein binding Human UniProtKB:Q9Y496 DISP1 UniProtKB UniProtKB {GO:0007368=GO_REF:0000019, GO:0007225=GO_REF:0000019, GO:0009953=GO_REF:0000019, GO:0007224=PMID:16258256, GO:0009880=GO_REF:0000019, GO:0070207=GO_REF:0000024, GO:0016323=GO_REF:0000024, GO:0015833=GO_REF:0000024, GO:0060539=PMID:20799323, GO:0008158=GO_REF:0000002, GO:0050708=GO_REF:0000024, GO:0016021=GO_REF:0000037, GO:0015197=GO_REF:0000024} Q96F81 Protein dispatched homolog 1 protein 20110107 {GO:0007368=IEA, GO:0007225=IEA, GO:0009953=IEA, GO:0007224=NAS, GO:0009880=IEA, GO:0070207=ISS, GO:0016323=ISS, GO:0015833=ISS, GO:0060539=IMP, GO:0008158=IEA, GO:0050708=ISS, GO:0016021=IEA, GO:0015197=ISS} determination of left/right symmetry, diaphragm development, dorsal/ventral pattern formation, embryonic pattern specification, patched ligand maturation, peptide transport, protein homotrimerization, regulation of protein secretion, smoothened signaling pathway basolateral plasma membrane, integral to membrane hedgehog receptor activity, peptide transporter activity Human DIXDC1 IntAct UniProtKB {GO:0005515=PMID:21189423, GO:0021695=GO_REF:0000033, GO:0021869=GO_REF:0000019, GO:0090263=PMID:21189423, GO:0046330=GO_REF:0000019, GO:0030177=GO_REF:0000019, GO:0005829=PMID:19375513, GO:0005622=GO_REF:0000002, GO:0046328=GO_REF:0000033, GO:0005737=GO_REF:0000019, GO:0032956=GO_REF:0000019, GO:0021799=GO_REF:0000019, GO:0043025=GO_REF:0000033, GO:0043679=GO_REF:0000033, GO:0043010=GO_REF:0000033, GO:0004871=GO_REF:0000002, GO:0005938=GO_REF:0000033, GO:0060071=GO_REF:0000033, GO:0043015=PMID:19375513, GO:0019904=GO_REF:0000019, GO:0031435=GO_REF:0000033, GO:0007275=GO_REF:0000002, GO:0003779=GO_REF:0000037, GO:0070507=GO_REF:0000019, GO:0043234=GO_REF:0000019, GO:0007049=GO_REF:0000019, GO:0045665=GO_REF:0000019, GO:0050772=GO_REF:0000033, GO:0030900=GO_REF:0000033, GO:0005925=GO_REF:0000039} Q155Q3 Dixin protein 20130415 {GO:0005515=IPI, GO:0021695=IBA, GO:0021869=IEA, GO:0090263=IDA, GO:0046330=IEA, GO:0030177=IEA, GO:0005829=IDA, GO:0005622=IEA, GO:0046328=IBA, GO:0005737=IEA, GO:0032956=IEA, GO:0021799=IEA, GO:0043025=IBA, GO:0043679=IBA, GO:0043010=IBA, GO:0004871=IEA, GO:0005938=IBA, GO:0060071=IRD, GO:0043015=IDA, GO:0019904=IEA, GO:0031435=IBA, GO:0007275=IEA, GO:0003779=IEA, GO:0070507=IEA, GO:0043234=IEA, GO:0007049=IEA, GO:0045665=IEA, GO:0050772=IBA, GO:0030900=IBA, GO:0005925=IEA} Wnt receptor signaling pathway, planar cell polarity pathway, camera-type eye development, cell cycle, cerebellar cortex development, cerebral cortex radially oriented cell migration, forebrain development, forebrain ventricular zone progenitor cell division, multicellular organismal development, negative regulation of neuron differentiation, positive regulation of JNK cascade, positive regulation of Wnt receptor signaling pathway, positive regulation of axonogenesis, positive regulation of canonical Wnt receptor signaling pathway, regulation of JNK cascade, regulation of actin cytoskeleton organization, regulation of microtubule cytoskeleton organization axon terminus, cell cortex, cytoplasm, cytosol, focal adhesion, intracellular, neuronal cell body, protein complex actin binding, gamma-tubulin binding, mitogen-activated protein kinase kinase kinase binding, protein binding, protein domain specific binding, signal transducer activity Human UniProtKB:Q60838 DKC1 HPA UniProtKB {GO:0009982=GO_REF:0000002, GO:0005515=PMID:18358808, GO:0006396=PMID:9590285, GO:0005697=PMID:12135483, GO:0015030=GO_REF:0000039, GO:0003720=PMID:12135483, GO:0008283=PMID:10591218, GO:0003723=GO_REF:0000037, GO:0006364=GO_REF:0000037, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0001522=GO_REF:0000002, GO:0005737=GO_REF:0000039, GO:0000723=Reactome:REACT_7970, GO:0005654=Reactome:REACT_8019, GO:0007004=Reactome:REACT_7974} O60832 H/ACA ribonucleoprotein complex subunit 4 protein 20080205 {GO:0009982=IEA, GO:0005515=IPI, GO:0006396=TAS, GO:0005697=IDA, GO:0015030=IEA, GO:0003720=IDA, GO:0008283=TAS, GO:0003723=IEA, GO:0006364=IEA, GO:0005730=IDA, GO:0005634=IDA, GO:0001522=IEA, GO:0005737=IEA, GO:0000723=TAS, GO:0005654=TAS, GO:0007004=TAS} RNA processing, cell proliferation, pseudouridine synthesis, rRNA processing, telomere maintenance, telomere maintenance via telomerase Cajal body, cytoplasm, nucleolus, nucleoplasm, nucleus, telomerase holoenzyme complex RNA binding, protein binding, pseudouridine synthase activity, telomerase activity NOT Human DKK1 GOC UniProtKB {GO:0005515=PMID:17804805, GO:0090082=GO_REF:0000024, GO:0005886=PMID:16263759, GO:0042662=PMID:20559569, GO:0042663=PMID:20559569, GO:0030326=GO_REF:0000019, GO:0090244=GO_REF:0000019, GO:0005615=PMID:11742004, GO:0030514=GO_REF:0000019, GO:0031333=PMID:11448771, GO:0033137=PMID:20723538, GO:0032526=GO_REF:0000019, GO:0004871=PMID:10383463, GO:0001942=GO_REF:0000019, GO:0090090=PMID:17804805, GO:0048019=PMID:20723538, GO:0001706=GO_REF:0000019, GO:0001707=GO_REF:0000019, GO:2000726=PMID:20559569, GO:0000122=GO_REF:0000024, GO:0048642=GO_REF:0000019, GO:0000904=GO_REF:0000019, GO:0060325=GO_REF:0000019, GO:1901296=PMID:20559569, GO:1900116=PMID:20723538, GO:0002090=PMID:17804805, GO:0030900=GO_REF:0000019, GO:0008083=PMID:10383463, GO:0050750=PMID:16263759} O94907 Dickkopf-related protein 1 protein 20130413 {GO:0005515=IPI, GO:0090082=ISS, GO:0005886=IDA, GO:0042662=IDA, GO:0042663=IDA, GO:0030326=IEA, GO:0090244=IEA, GO:0005615=IDA, GO:0030514=IEA, GO:0031333=IDA, GO:0033137=IDA, GO:0032526=IEA, GO:0004871=TAS, GO:0001942=IEA, GO:0090090=IDA, GO:0048019=IDA, GO:0001706=IEA, GO:0001707=IEA, GO:2000726=IDA, GO:0000122=ISS, GO:0048642=IEA, GO:0000904=IEA, GO:0060325=IEA, GO:1901296=IDA, GO:1900116=IDA, GO:0002090=IDA, GO:0030900=IEA, GO:0008083=TAS, GO:0050750=IDA} Wnt receptor signaling pathway involved in somitogenesis, cell morphogenesis involved in differentiation, embryonic limb morphogenesis, endoderm formation, extracellular negative regulation of signal transduction, face morphogenesis, forebrain development, hair follicle development, mesoderm formation, negative regulation of BMP signaling pathway, negative regulation of canonical Wnt receptor signaling pathway, negative regulation of canonical Wnt receptor signaling pathway involved in cardiac muscle cell fate commitment, negative regulation of cardiac muscle cell differentiation, negative regulation of mesodermal cell fate specification, negative regulation of peptidyl-serine phosphorylation, negative regulation of protein complex assembly, negative regulation of skeletal muscle tissue development, negative regulation of transcription from RNA polymerase II promoter, positive regulation of heart induction by negative regulation of canonical Wnt receptor signaling pathway, regulation of endodermal cell fate specification, regulation of receptor internalization, response to retinoic acid extracellular space, plasma membrane growth factor activity, low-density lipoprotein particle receptor binding, protein binding, receptor antagonist activity, signal transducer activity Human DKK2 BHF-UCL UniProtKB {GO:0090263=PMID:12857724, GO:0030178=GO_REF:0000002, GO:0007275=GO_REF:0000037, GO:0005576=GO_REF:0000002, GO:0016055=GO_REF:0000037, GO:0090090=PMID:11742004, GO:0005615=PMID:11742004} Q9UBU2 Dickkopf-related protein 2 protein 20100930 {GO:0090263=IDA, GO:0030178=IEA, GO:0007275=IEA, GO:0005576=IEA, GO:0016055=IEA, GO:0090090=IDA, GO:0005615=IDA} Wnt receptor signaling pathway, multicellular organismal development, negative regulation of Wnt receptor signaling pathway, negative regulation of canonical Wnt receptor signaling pathway, positive regulation of canonical Wnt receptor signaling pathway extracellular region, extracellular space Human DKK3 BHF-UCL UniProtKB {GO:0030325=PMID:12844346, GO:2000065=PMID:16981135, GO:0030178=GO_REF:0000002, GO:0007275=GO_REF:0000002, GO:0005576=GO_REF:0000002, GO:0016055=GO_REF:0000037, GO:0090090=PMID:12857724, GO:0009653=PMID:10570958, GO:0005615=PMID:10570958, GO:0045892=PMID:16981135, GO:0032348=PMID:16981135} Q9UBP4 Dickkopf-related protein 3 protein 20110331 {GO:0030325=IEP, GO:2000065=IDA, GO:0030178=IEA, GO:0007275=IEA, GO:0005576=IEA, GO:0016055=IEA, GO:0090090=IDA, GO:0009653=TAS, GO:0005615=TAS, GO:0045892=IDA, GO:0032348=IDA} Wnt receptor signaling pathway, adrenal gland development, anatomical structure morphogenesis, multicellular organismal development, negative regulation of Wnt receptor signaling pathway, negative regulation of aldosterone biosynthetic process, negative regulation of canonical Wnt receptor signaling pathway, negative regulation of cortisol biosynthetic process, negative regulation of transcription, DNA-dependent extracellular region, extracellular space Human DKKL1 GOC UniProtKB {GO:0007165=PMID:10570958, GO:0045600=GO_REF:0000019, GO:0004871=PMID:10570958, GO:0009653=PMID:10570958, GO:0005615=PMID:10570958} Q9UK85 Dickkopf-like protein 1 protein 20130413 {GO:0007165=TAS, GO:0045600=IEA, GO:0004871=TAS, GO:0009653=TAS, GO:0005615=TAS} anatomical structure morphogenesis, positive regulation of fat cell differentiation, signal transduction extracellular space signal transducer activity Human DLAT Reactome UniProtKB {GO:0005515=PMID:15861126, GO:0010510=Reactome:REACT_12528, GO:0004742=PMID:3191998, GO:0006099=GO_REF:0000037, GO:0005967=PMID:3191998, GO:0006090=Reactome:REACT_2071, GO:0005759=Reactome:REACT_12543, GO:0006006=GO_REF:0000037, GO:0044281=Reactome:REACT_111217, GO:0006085=GO_REF:0000029, GO:0045254=GO_REF:0000002} P10515 Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial protein 20130213 {GO:0005515=IPI, GO:0010510=TAS, GO:0004742=NAS, GO:0006099=IEA, GO:0005967=NAS, GO:0006090=TAS, GO:0005759=TAS, GO:0006006=IEA, GO:0044281=TAS, GO:0006085=NAS, GO:0045254=IEA} acetyl-CoA biosynthetic process, glucose metabolic process, pyruvate metabolic process, regulation of acetyl-CoA biosynthetic process from pyruvate, small molecule metabolic process, tricarboxylic acid cycle mitochondrial matrix, mitochondrial pyruvate dehydrogenase complex, pyruvate dehydrogenase complex dihydrolipoyllysine-residue acetyltransferase activity, protein binding Human DLC1 GOC UniProtKB {GO:0005515=PMID:16951145, GO:0008285=PMID:17932950, GO:0030036=GO_REF:0000024, GO:0007264=Reactome:REACT_11044, GO:0035024=PMID:16951145, GO:0008360=PMID:17292327, GO:0005634=PMID:17888903, GO:0021575=GO_REF:0000024, GO:0005829=Reactome:REACT_9982, GO:0005622=GO_REF:0000002, GO:0005737=PMID:17888903, GO:0032956=PMID:17292327, GO:0048041=GO_REF:0000024, GO:0030675=PMID:17932950, GO:0042169=PMID:17190795, GO:0051056=Reactome:REACT_11051, GO:0030336=PMID:17932950, GO:0006919=PMID:17888903, GO:0035307=PMID:17292327, GO:0001843=GO_REF:0000024, GO:0006917=PMID:17888903, GO:0005100=PMID:17932950, GO:0051497=PMID:17932950, GO:0007165=GO_REF:0000002, GO:0003007=GO_REF:0000024, GO:0032321=PMID:17932950, GO:0005901=PMID:16951145, GO:0030900=GO_REF:0000024, GO:0005925=PMID:17190795} Q96QB1 Rho GTPase-activating protein 7 protein 20130413 {GO:0005515=IPI, GO:0008285=IDA, GO:0030036=ISS, GO:0007264=TAS, GO:0035024=IMP, GO:0008360=IMP, GO:0005634=IDA, GO:0021575=ISS, GO:0005829=TAS, GO:0005622=IEA, GO:0005737=IDA, GO:0032956=IMP, GO:0048041=ISS, GO:0030675=IDA, GO:0042169=IPI, GO:0051056=TAS, GO:0030336=IDA, GO:0006919=IDA, GO:0035307=IDA, GO:0001843=ISS, GO:0006917=IDA, GO:0005100=IDA, GO:0051497=IDA, GO:0007165=IEA, GO:0003007=ISS, GO:0032321=IDA, GO:0005901=IDA, GO:0030900=ISS, GO:0005925=IDA} actin cytoskeleton organization, activation of cysteine-type endopeptidase activity involved in apoptotic process, focal adhesion assembly, forebrain development, heart morphogenesis, hindbrain morphogenesis, induction of apoptosis, negative regulation of Rho protein signal transduction, negative regulation of cell migration, negative regulation of cell proliferation, negative regulation of stress fiber assembly, neural tube closure, positive regulation of Rho GTPase activity, positive regulation of protein dephosphorylation, regulation of actin cytoskeleton organization, regulation of cell shape, regulation of small GTPase mediated signal transduction, signal transduction, small GTPase mediated signal transduction caveola, cytoplasm, cytosol, focal adhesion, intracellular, nucleus Rac GTPase activator activity, Rho GTPase activator activity, SH2 domain binding, protein binding Human DLD HPA UniProtKB {GO:0010510=Reactome:REACT_12528, GO:0006099=Reactome:REACT_1785, GO:0007369=GO_REF:0000019, GO:0043159=GO_REF:0000019, GO:0050660=GO_REF:0000002, GO:0005730=GO_REF:0000052, GO:0009083=Reactome:REACT_197, GO:0005634=GO_REF:0000052, GO:0044281=Reactome:REACT_111217, GO:0005739=GO_REF:0000052, GO:0034641=Reactome:REACT_13, GO:0006090=Reactome:REACT_2071, GO:0005759=Reactome:REACT_12543, GO:0042391=GO_REF:0000019, GO:0006120=GO_REF:0000019, GO:0006508=GO_REF:0000019, GO:0045454=GO_REF:0000002, GO:0006554=Reactome:REACT_1298, GO:0004148=GO_REF:0000003, GO:0048240=GO_REF:0000019} P09622 Dihydrolipoyl dehydrogenase, mitochondrial protein 20120912 {GO:0010510=TAS, GO:0006099=TAS, GO:0007369=IEA, GO:0043159=IEA, GO:0050660=IEA, GO:0005730=IDA, GO:0009083=TAS, GO:0005634=IDA, GO:0044281=TAS, GO:0005739=IDA, GO:0034641=TAS, GO:0006090=TAS, GO:0005759=TAS, GO:0042391=IEA, GO:0006120=IEA, GO:0006508=IEA, GO:0045454=IEA, GO:0006554=TAS, GO:0004148=IEA, GO:0048240=IEA} branched-chain amino acid catabolic process, cell redox homeostasis, cellular nitrogen compound metabolic process, gastrulation, lysine catabolic process, mitochondrial electron transport, NADH to ubiquinone, proteolysis, pyruvate metabolic process, regulation of acetyl-CoA biosynthetic process from pyruvate, regulation of membrane potential, small molecule metabolic process, sperm capacitation, tricarboxylic acid cycle acrosomal matrix, mitochondrial matrix, mitochondrion, nucleolus, nucleus dihydrolipoyl dehydrogenase activity, flavin adenine dinucleotide binding Human DLG1 BHF-UCL UniProtKB {GO:0008092=PMID:8825652, GO:0005515=PMID:12097473, GO:0001658=GO_REF:0000019, GO:0031594=GO_REF:0000019, GO:0030054=PMID:17237226, GO:0050680=GO_REF:0000019, GO:0043268=PMID:12970345, GO:0015459=PMID:10779557, GO:0048704=GO_REF:0000019, GO:0042130=GO_REF:0000019, GO:0048608=GO_REF:0000019, GO:0016337=PMID:14699157, GO:0070830=PMID:17332497, GO:0030838=GO_REF:0000019, GO:0007411=Reactome:REACT_18266, GO:0048745=GO_REF:0000019, GO:0045211=GO_REF:0000037, GO:0035748=GO_REF:0000019, GO:0002369=GO_REF:0000019, GO:0019901=PMID:10779557, GO:0019902=PMID:10646847, GO:0014069=GO_REF:0000039, GO:0031434=PMID:21615688, GO:0030432=GO_REF:0000019, GO:0044325=PMID:12970345, GO:0042110=GO_REF:0000019, GO:0045930=PMID:10656683, GO:0005789=GO_REF:0000039, GO:0045121=GO_REF:0000019, GO:0005923=PMID:17332497, GO:0031579=GO_REF:0000019, GO:0008284=GO_REF:0000019, GO:0007093=PMID:10656683, GO:0005886=Reactome:REACT_21414, GO:0097025=PMID:17237226, GO:0007268=Reactome:REACT_13685, GO:0005634=PMID:17237226, GO:0005829=Reactome:REACT_18393, GO:0032147=GO_REF:0000019, GO:0016323=PMID:8922391, GO:0005737=PMID:17237226, GO:0008104=GO_REF:0000019, GO:0002088=GO_REF:0000019, GO:0042391=PMID:12970345, GO:0007015=PMID:14699157, GO:0004721=PMID:15302935, GO:0097016=PMID:17332497, GO:0060022=GO_REF:0000019, GO:0001772=PMID:19841189, GO:0001771=GO_REF:0000019, GO:0031253=GO_REF:0000019, GO:0004385=PMID:7937897, GO:0042982=GO_REF:0000019, GO:0008022=PMID:11274188, GO:0072659=PMID:17332497, GO:0016328=GO_REF:0000019, GO:0042383=GO_REF:0000039, GO:0032947=GO_REF:0000019, GO:0033268=GO_REF:0000019, GO:0007163=PMID:12766944, GO:0030866=PMID:14699157, GO:0019048=GO_REF:0000037, GO:0043219=GO_REF:0000019, GO:0001935=PMID:14699157} Q12959 Disks large homolog 1 protein 20120919 {GO:0008092=TAS, GO:0005515=IPI, GO:0001658=IEA, GO:0031594=IEA, GO:0030054=IDA, GO:0050680=IEA, GO:0043268=IDA, GO:0015459=NAS, GO:0048704=IEA, GO:0042130=IEA, GO:0048608=IEA, GO:0016337=IDA, GO:0070830=IDA, GO:0030838=IEA, GO:0007411=TAS, GO:0048745=IEA, GO:0045211=IEA, GO:0035748=IEA, GO:0002369=IEA, GO:0019901=IPI, GO:0019902=IPI, GO:0014069=IEA, GO:0031434=IPI, GO:0030432=IEA, GO:0044325=IPI, GO:0042110=IEA, GO:0045930=IMP, GO:0005789=IEA, GO:0045121=IEA, GO:0005923=IDA, GO:0031579=IEA, GO:0008284=IEA, GO:0007093=NAS, GO:0005886=TAS, GO:0097025=IDA, GO:0007268=TAS, GO:0005634=IDA, GO:0005829=TAS, GO:0032147=IEA, GO:0016323=IDA, GO:0005737=IDA, GO:0008104=IEA, GO:0002088=IEA, GO:0042391=IDA, GO:0007015=IDA, GO:0004721=TAS, GO:0097016=IPI, GO:0060022=IEA, GO:0001772=TAS, GO:0001771=IEA, GO:0031253=IEA, GO:0004385=TAS, GO:0042982=IEA, GO:0008022=IPI, GO:0072659=IMP, GO:0016328=IEA, GO:0042383=IEA, GO:0032947=IEA, GO:0033268=IEA, GO:0007163=TAS, GO:0030866=IDA, GO:0019048=IEA, GO:0043219=IEA, GO:0001935=IDA} T cell activation, T cell cytokine production, actin filament organization, activation of protein kinase activity, amyloid precursor protein metabolic process, axon guidance, branching involved in ureteric bud morphogenesis, cell-cell adhesion, cortical actin cytoskeleton organization, embryonic skeletal system morphogenesis, endothelial cell proliferation, establishment or maintenance of cell polarity, hard palate development, immunological synapse formation, lens development in camera-type eye, membrane raft organization, mitotic cell cycle checkpoint, negative regulation of T cell proliferation, negative regulation of epithelial cell proliferation, negative regulation of mitotic cell cycle, peristalsis, positive regulation of actin filament polymerization, positive regulation of cell proliferation, positive regulation of potassium ion transport, protein localization, protein localization to plasma membrane, regulation of membrane potential, reproductive structure development, smooth muscle tissue development, synaptic transmission, tight junction assembly, virus-host interaction MPP7-DLG1-LIN7 complex, basolateral plasma membrane, cell junction, cell projection membrane, cytoplasm, cytosol, endoplasmic reticulum membrane, immunological synapse, lateral loop, lateral plasma membrane, membrane raft, myelin sheath abaxonal region, neuromuscular junction, node of Ranvier, nucleus, plasma membrane, postsynaptic density, postsynaptic membrane, sarcolemma, tight junction L27 domain binding, cytoskeletal protein binding, guanylate kinase activity, ion channel binding, mitogen-activated protein kinase kinase binding, phosphatase binding, phosphoprotein phosphatase activity, potassium channel regulator activity, protein C-terminus binding, protein binding, protein complex scaffold, protein kinase binding Human DLG2 PINC UniProtKB {GO:0005515=PMID:19118189, GO:0030054=GO_REF:0000019, GO:0005886=GO_REF:0000037, GO:0044224=GO_REF:0000019, GO:0010923=PMID:19389623, GO:0045211=GO_REF:0000019, GO:0004385=PMID:8755482, GO:0014069=GO_REF:0000039, GO:0007268=GO_REF:0000019, GO:0019233=GO_REF:0000019} Q15700 Disks large homolog 2 protein 20030904 {GO:0005515=IPI, GO:0030054=IEA, GO:0005886=IEA, GO:0044224=IEA, GO:0010923=IDA, GO:0045211=IEA, GO:0004385=TAS, GO:0014069=IEA, GO:0007268=IEA, GO:0019233=IEA} negative regulation of phosphatase activity, sensory perception of pain, synaptic transmission cell junction, juxtaparanode region of axon, plasma membrane, postsynaptic density, postsynaptic membrane guanylate kinase activity, protein binding Human DLG3 IntAct UniProtKB {GO:0005515=PMID:19389623, GO:0001736=GO_REF:0000019, GO:0008285=PMID:9188857, GO:0005886=Reactome:REACT_21414, GO:0019902=PMID:19389623, GO:0019903=GO_REF:0000019, GO:0007268=Reactome:REACT_13685, GO:0004385=GO_REF:0000029, GO:0045202=GO_REF:0000019, GO:0008022=GO_REF:0000019, GO:0030165=GO_REF:0000019, GO:0030426=GO_REF:0000019, GO:0045197=GO_REF:0000019, GO:0005737=GO_REF:0000019, GO:0035255=GO_REF:0000019, GO:0007411=Reactome:REACT_18266, GO:0043198=GO_REF:0000019, GO:0010923=PMID:19389623, GO:0043025=GO_REF:0000019, GO:0005923=GO_REF:0000019, GO:0031625=GO_REF:0000019} Q92796 Disks large homolog 3 protein 20130415 {GO:0005515=IPI, GO:0001736=IEA, GO:0008285=NAS, GO:0005886=TAS, GO:0019902=IDA, GO:0019903=IEA, GO:0007268=TAS, GO:0004385=NAS, GO:0045202=IEA, GO:0008022=IEA, GO:0030165=IEA, GO:0030426=IEA, GO:0045197=IEA, GO:0005737=IEA, GO:0035255=IEA, GO:0007411=TAS, GO:0043198=IEA, GO:0010923=IDA, GO:0043025=IEA, GO:0005923=IEA, GO:0031625=IEA} axon guidance, establishment of planar polarity, establishment or maintenance of epithelial cell apical/basal polarity, negative regulation of cell proliferation, negative regulation of phosphatase activity, synaptic transmission cytoplasm, dendritic shaft, growth cone, neuronal cell body, plasma membrane, synapse, tight junction PDZ domain binding, guanylate kinase activity, ionotropic glutamate receptor binding, phosphatase binding, protein C-terminus binding, protein binding, protein phosphatase binding, ubiquitin protein ligase binding Human UniProtKB:P62136 DLG4 BHF-UCL UniProtKB {GO:0005515=PMID:16767099, GO:0030054=GO_REF:0000019, GO:0008328=GO_REF:0000024, GO:2000310=GO_REF:0000024, GO:0045202=PMID:15496675, GO:0031697=GO_REF:0000019, GO:0032403=GO_REF:0000019, GO:0007411=Reactome:REACT_18266, GO:0045211=PMID:12151521, GO:0048169=GO_REF:0000019, GO:0050885=GO_REF:0000019, GO:0007612=PMID:9853749, GO:0060997=GO_REF:0000024, GO:0035641=GO_REF:0000019, GO:2000821=GO_REF:0000019, GO:2000463=GO_REF:0000024, GO:0044224=GO_REF:0000019, GO:0019903=GO_REF:0000019, GO:0014069=GO_REF:0000024, GO:0045032=GO_REF:0000024, GO:0030165=GO_REF:0000019, GO:0045031=GO_REF:0000024, GO:0071625=GO_REF:0000019, GO:0060076=GO_REF:0000024, GO:0031234=GO_REF:0000019, GO:0050806=GO_REF:0000024, GO:0035176=GO_REF:0000019, GO:0005886=GO_REF:0000024, GO:0007268=Reactome:REACT_13685, GO:0097120=GO_REF:0000024, GO:0035418=PMID:15496675, GO:0032839=GO_REF:0000024, GO:0045184=PMID:15496675, GO:0031812=GO_REF:0000024, GO:0097113=GO_REF:0000024, GO:0045944=GO_REF:0000024, GO:0032281=GO_REF:0000019, GO:0097110=GO_REF:0000024, GO:0044306=GO_REF:0000019, GO:0008022=PMID:7477295, GO:0044309=GO_REF:0000024, GO:0007399=PMID:9286702, GO:0008021=GO_REF:0000019, GO:0030666=Reactome:REACT_18393, GO:0007165=PMID:10364559, GO:0006461=PMID:15496675, GO:0001973=GO_REF:0000024, GO:0035255=GO_REF:0000024, GO:0016188=GO_REF:0000019, GO:0030863=PMID:12151521, GO:0002091=GO_REF:0000019} P78352 Disks large homolog 4 protein 20120314 {GO:0005515=IPI, GO:0030054=IEA, GO:0008328=ISS, GO:2000310=ISS, GO:0045202=IDA, GO:0031697=IEA, GO:0032403=IEA, GO:0007411=TAS, GO:0045211=IDA, GO:0048169=IEA, GO:0050885=IEA, GO:0007612=TAS, GO:0060997=ISS, GO:0035641=IEA, GO:2000821=IEA, GO:2000463=ISS, GO:0044224=IEA, GO:0019903=IEA, GO:0014069=ISS, GO:0045032=ISS, GO:0030165=IEA, GO:0045031=ISS, GO:0071625=IEA, GO:0060076=ISS, GO:0031234=IEA, GO:0050806=ISS, GO:0035176=IEA, GO:0005886=ISS, GO:0007268=TAS, GO:0097120=ISS, GO:0035418=IDA, GO:0032839=ISS, GO:0045184=IDA, GO:0031812=ISS, GO:0097113=ISS, GO:0045944=ISS, GO:0032281=IEA, GO:0097110=ISS, GO:0044306=IEA, GO:0008022=IPI, GO:0044309=ISS, GO:0007399=TAS, GO:0008021=IEA, GO:0030666=TAS, GO:0007165=TAS, GO:0006461=IDA, GO:0001973=ISS, GO:0035255=ISS, GO:0016188=IEA, GO:0030863=IDA, GO:0002091=IEA} adenosine receptor signaling pathway, alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate receptor clustering, axon guidance, dendritic spine morphogenesis, establishment of protein localization, learning, locomotory exploration behavior, negative regulation of receptor internalization, nervous system development, neuromuscular process controlling balance, positive regulation of excitatory postsynaptic membrane potential, positive regulation of synaptic transmission, positive regulation of transcription from RNA polymerase II promoter, protein complex assembly, protein localization to synapse, receptor localization to synapse, regulation of N-methyl-D-aspartate selective glutamate receptor activity, regulation of grooming behavior, regulation of long-term neuronal synaptic plasticity, signal transduction, social behavior, synaptic transmission, synaptic vesicle maturation, vocalization behavior alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid selective glutamate receptor complex, cell junction, cortical cytoskeleton, dendrite cytoplasm, endocytic vesicle membrane, excitatory synapse, extrinsic to internal side of plasma membrane, ionotropic glutamate receptor complex, juxtaparanode region of axon, neuron projection terminus, neuron spine, plasma membrane, postsynaptic density, postsynaptic membrane, synapse, synaptic vesicle ADP-activated nucleotide receptor activity, ATP-activated nucleotide receptor activity, P2Y1 nucleotide receptor binding, PDZ domain binding, beta-1 adrenergic receptor binding, ionotropic glutamate receptor binding, protein C-terminus binding, protein binding, protein complex binding, protein phosphatase binding, scaffold protein binding Human UniProtKB:P31016 DLG5 PINC UniProtKB {GO:0008092=PMID:12657639, GO:0035556=PMID:12353226, GO:0007165=PMID:9738934, GO:0005737=PMID:9738934, GO:0016337=PMID:12353226, GO:0008285=PMID:9738934, GO:0005913=GO_REF:0000019, GO:0008013=PMID:12657639, GO:0005886=GO_REF:0000029, GO:0030159=PMID:12353226, GO:0042981=GO_REF:0000002} Q8TDM6 Disks large homolog 5 protein 20050308 {GO:0008092=IDA, GO:0035556=NAS, GO:0007165=TAS, GO:0005737=TAS, GO:0016337=NAS, GO:0008285=TAS, GO:0005913=IEA, GO:0008013=IDA, GO:0005886=NAS, GO:0030159=NAS, GO:0042981=IEA} cell-cell adhesion, intracellular signal transduction, negative regulation of cell proliferation, regulation of apoptotic process, signal transduction cell-cell adherens junction, cytoplasm, plasma membrane beta-catenin binding, cytoskeletal protein binding, receptor signaling complex scaffold activity Human DLGAP1 IntAct UniProtKB {GO:0005515=PMID:20936779, GO:0030054=GO_REF:0000037, GO:0005886=GO_REF:0000039, GO:0045211=GO_REF:0000037, GO:0007267=GO_REF:0000002, GO:0007268=PMID:9286858, GO:0014069=GO_REF:0000039, GO:0005575=GO_REF:0000015} O14490 Disks large-associated protein 1 protein 20130415 {GO:0005515=IPI, GO:0030054=IEA, GO:0005886=IEA, GO:0045211=IEA, GO:0007267=IEA, GO:0007268=NAS, GO:0014069=IEA, GO:0005575=ND} cell-cell signaling, synaptic transmission cell junction, cellular_component, plasma membrane, postsynaptic density, postsynaptic membrane protein binding Human UniProtKB:P62993 DLGAP2 IntAct UniProtKB {GO:0005515=PMID:17474147, GO:0030054=GO_REF:0000037, GO:0005886=GO_REF:0000039, GO:0045211=GO_REF:0000037, GO:0005883=PMID:10759891, GO:0007267=GO_REF:0000002, GO:0014069=GO_REF:0000039, GO:0007270=PMID:9694864} Q9P1A6 Disks large-associated protein 2 protein 20130415 {GO:0005515=IPI, GO:0030054=IEA, GO:0005886=IEA, GO:0045211=IEA, GO:0005883=NAS, GO:0007267=IEA, GO:0014069=IEA, GO:0007270=NAS} cell-cell signaling, neuron-neuron synaptic transmission cell junction, neurofilament, plasma membrane, postsynaptic density, postsynaptic membrane protein binding Human UniProtKB:P62993 DLGAP3 IntAct UniProtKB {GO:0005515=PMID:17474147, GO:0001540=GO_REF:0000019, GO:0030054=GO_REF:0000037, GO:0005886=GO_REF:0000039, GO:0045211=GO_REF:0000037, GO:0007267=GO_REF:0000002, GO:0014069=GO_REF:0000039} O95886 Disks large-associated protein 3 protein 20130415 {GO:0005515=IPI, GO:0001540=IEA, GO:0030054=IEA, GO:0005886=IEA, GO:0045211=IEA, GO:0007267=IEA, GO:0014069=IEA} cell-cell signaling cell junction, plasma membrane, postsynaptic density, postsynaptic membrane beta-amyloid binding, protein binding Human UniProtKB:P16333 DLGAP4 IntAct UniProtKB {GO:0005515=PMID:17474147, GO:0016020=GO_REF:0000039, GO:0007267=GO_REF:0000002, GO:0045202=GO_REF:0000019} Q9Y2H0 Disks large-associated protein 4 protein 20130415 {GO:0005515=IPI, GO:0016020=IEA, GO:0007267=IEA, GO:0045202=IEA} cell-cell signaling membrane, synapse protein binding Human UniProtKB:P62993 DLGAP5 UniProtKB UniProtKB {GO:0005515=PMID:15987997, GO:0005737=GO_REF:0000039, GO:0008283=PMID:12527899, GO:0000087=GO_REF:0000024, GO:0045842=PMID:12527899, GO:0007267=GO_REF:0000002, GO:0004721=GO_REF:0000024, GO:0005634=GO_REF:0000024, GO:0031616=PMID:12527899, GO:0007079=PMID:12527899} Q15398 Disks large-associated protein 5 protein 20090424 {GO:0005515=IPI, GO:0005737=IEA, GO:0008283=NAS, GO:0000087=ISS, GO:0045842=NAS, GO:0007267=IEA, GO:0004721=ISS, GO:0005634=ISS, GO:0031616=IDA, GO:0007079=NAS} M phase of mitotic cell cycle, cell proliferation, cell-cell signaling, mitotic chromosome movement towards spindle pole, positive regulation of mitotic metaphase/anaphase transition cytoplasm, nucleus, spindle pole centrosome phosphoprotein phosphatase activity, protein binding Human UniProtKB:O14965 DLK1 Reactome UniProtKB {GO:0003674=GO_REF:0000015, GO:0045746=GO_REF:0000019, GO:0007219=Reactome:REACT_118859, GO:0048706=GO_REF:0000019, GO:0007275=PMID:8500166, GO:0016021=GO_REF:0000037, GO:0009791=GO_REF:0000019, GO:0005615=PMID:7925474, GO:0009897=GO_REF:0000019} P80370 Protein delta homolog 1 protein 20110915 {GO:0003674=ND, GO:0045746=IEA, GO:0007219=TAS, GO:0048706=IEA, GO:0007275=TAS, GO:0016021=IEA, GO:0009791=IEA, GO:0005615=TAS, GO:0009897=IEA} Notch signaling pathway, embryonic skeletal system development, multicellular organismal development, negative regulation of Notch signaling pathway, post-embryonic development external side of plasma membrane, extracellular space, integral to membrane molecular_function Human DLK2 ENSEMBL UniProtKB {GO:0045746=GO_REF:0000019, GO:0046982=GO_REF:0000019, GO:0045598=GO_REF:0000019, GO:0005509=GO_REF:0000002, GO:0016021=GO_REF:0000037, GO:0042803=GO_REF:0000019} Q6UY11 Protein delta homolog 2 protein 20130413 {GO:0045746=IEA, GO:0046982=IEA, GO:0045598=IEA, GO:0005509=IEA, GO:0016021=IEA, GO:0042803=IEA} negative regulation of Notch signaling pathway, regulation of fat cell differentiation integral to membrane calcium ion binding, protein heterodimerization activity, protein homodimerization activity Human Ensembl:ENSMUSP00000058470 DLL1 BHF-UCL UniProtKB {GO:0005515=PMID:10079256, GO:0007368=GO_REF:0000024, GO:0007386=GO_REF:0000019, GO:0007220=Reactome:REACT_2001, GO:0005886=Reactome:REACT_160273, GO:0072014=GO_REF:0000019, GO:0001757=GO_REF:0000019, GO:0007267=GO_REF:0000019, GO:0005112=PMID:11823422, GO:0070986=GO_REF:0000019, GO:0030155=PMID:11912004, GO:0030154=PMID:11912004, GO:0001947=GO_REF:0000024, GO:0007219=Reactome:REACT_118862, GO:0045638=GO_REF:0000019, GO:0045944=GO_REF:0000024, GO:0045747=GO_REF:0000019, GO:0030097=PMID:11581320, GO:0097150=PMID:19682396, GO:0048839=GO_REF:0000019, GO:0001709=PMID:11581320, GO:0005509=GO_REF:0000002, GO:0005576=PMID:11823422, GO:0031410=GO_REF:0000019, GO:0045608=GO_REF:0000019, GO:0072070=GO_REF:0000019, GO:0005887=PMID:10079256} O00548 Delta-like protein 1 protein 20120727 {GO:0005515=IPI, GO:0007368=ISS, GO:0007386=IEA, GO:0007220=TAS, GO:0005886=TAS, GO:0072014=IEA, GO:0001757=IEA, GO:0007267=IEA, GO:0005112=IPI, GO:0070986=IEA, GO:0030155=TAS, GO:0030154=TAS, GO:0001947=ISS, GO:0007219=TAS, GO:0045638=IEA, GO:0045944=ISS, GO:0045747=IEA, GO:0030097=NAS, GO:0097150=IEP, GO:0048839=IEA, GO:0001709=NAS, GO:0005509=IEA, GO:0005576=NAS, GO:0031410=IEA, GO:0045608=IEA, GO:0072070=IEA, GO:0005887=NAS} Notch receptor processing, Notch signaling pathway, cell differentiation, cell fate determination, cell-cell signaling, compartment pattern specification, determination of left/right symmetry, heart looping, hemopoiesis, inner ear development, left/right axis specification, loop of Henle development, negative regulation of auditory receptor cell differentiation, negative regulation of myeloid cell differentiation, neuronal stem cell maintenance, positive regulation of Notch signaling pathway, positive regulation of transcription from RNA polymerase II promoter, proximal tubule development, regulation of cell adhesion, somite specification cytoplasmic vesicle, extracellular region, integral to plasma membrane, plasma membrane Notch binding, calcium ion binding, protein binding Human UniProtKB:Q61483 DLL3 UniProtKB UniProtKB {GO:0001501=PMID:10742114, GO:0048339=GO_REF:0000019, GO:0007386=GO_REF:0000019, GO:0050768=GO_REF:0000019, GO:0007219=GO_REF:0000037, GO:0001756=GO_REF:0000019, GO:0005112=PMID:10742114, GO:0007275=GO_REF:0000002, GO:0016021=PMID:10742114} Q9NYJ7 Delta-like protein 3 protein 20020806 {GO:0001501=IMP, GO:0048339=IEA, GO:0007386=IEA, GO:0050768=IEA, GO:0007219=IEA, GO:0001756=IEA, GO:0005112=NAS, GO:0007275=IEA, GO:0016021=NAS} Notch signaling pathway, compartment pattern specification, multicellular organismal development, negative regulation of neurogenesis, paraxial mesoderm development, skeletal system development, somitogenesis integral to membrane Notch binding Human DLL4 BHF-UCL UniProtKB {GO:0001569=GO_REF:0000024, GO:0035912=GO_REF:0000024, GO:0007220=Reactome:REACT_2001, GO:0005886=Reactome:REACT_160320, GO:0008015=PMID:10837024, GO:0005509=GO_REF:0000002, GO:0005112=GO_REF:0000019, GO:0001525=GO_REF:0000024, GO:0072554=GO_REF:0000019, GO:0000122=GO_REF:0000024, GO:0003208=GO_REF:0000024, GO:0003344=GO_REF:0000024, GO:0003209=GO_REF:0000024, GO:0007165=PMID:10837024, GO:0061314=GO_REF:0000024, GO:0050767=GO_REF:0000019, GO:0007219=Reactome:REACT_118862, GO:0001974=GO_REF:0000024, GO:0003222=GO_REF:0000024, GO:0016021=GO_REF:0000037, GO:0043537=GO_REF:0000019} Q9NR61 Delta-like protein 4 protein 20120925 {GO:0001569=ISS, GO:0035912=ISS, GO:0007220=TAS, GO:0005886=TAS, GO:0008015=TAS, GO:0005509=IEA, GO:0005112=IEA, GO:0001525=ISS, GO:0072554=IEA, GO:0000122=ISS, GO:0003208=ISS, GO:0003344=ISS, GO:0003209=ISS, GO:0007165=TAS, GO:0061314=ISS, GO:0050767=IEA, GO:0007219=TAS, GO:0001974=ISS, GO:0003222=ISS, GO:0016021=IEA, GO:0043537=IEA} Notch receptor processing, Notch signaling involved in heart development, Notch signaling pathway, angiogenesis, blood circulation, blood vessel lumenization, blood vessel remodeling, cardiac atrium morphogenesis, cardiac ventricle morphogenesis, dorsal aorta morphogenesis, negative regulation of blood vessel endothelial cell migration, negative regulation of transcription from RNA polymerase II promoter, patterning of blood vessels, pericardium morphogenesis, regulation of neurogenesis, signal transduction, ventricular trabecula myocardium morphogenesis integral to membrane, plasma membrane Notch binding, calcium ion binding Human UniProtKB:Q9JI71 DLST UniProtKB UniProtKB {GO:0004149=GO_REF:0000003, GO:0016746=GO_REF:0000038, GO:0006099=Reactome:REACT_1785, GO:0033512=GO_REF:0000041, GO:0005634=GO_REF:0000052, GO:0044281=Reactome:REACT_111217, GO:0006091=PMID:8009371, GO:0043231=GO_REF:0000052, GO:0005739=GO_REF:0000052, GO:0034641=Reactome:REACT_13, GO:0005737=GO_REF:0000052, GO:0005759=Reactome:REACT_1865, GO:0006554=Reactome:REACT_1298, GO:0045252=GO_REF:0000002, GO:0016740=GO_REF:0000038} Q86SW4 Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial protein 20130413 {GO:0004149=IEA, GO:0016746=IEA, GO:0006099=TAS, GO:0033512=IEA, GO:0005634=IDA, GO:0044281=TAS, GO:0006091=TAS, GO:0043231=IDA, GO:0005739=IDA, GO:0034641=TAS, GO:0005737=IDA, GO:0005759=TAS, GO:0006554=TAS, GO:0045252=IEA, GO:0016740=IEA} L-lysine catabolic process to acetyl-CoA via saccharopine, cellular nitrogen compound metabolic process, generation of precursor metabolites and energy, lysine catabolic process, small molecule metabolic process, tricarboxylic acid cycle cytoplasm, intracellular membrane-bounded organelle, mitochondrial matrix, mitochondrion, nucleus, oxoglutarate dehydrogenase complex dihydrolipoyllysine-residue succinyltransferase activity, transferase activity, transferase activity, transferring acyl groups Human UniProtKB-KW:KW-0012 DLX1 UniProtKB UniProtKB {GO:0000976=GO_REF:0000002, GO:0003700=GO_REF:0000002, GO:0048706=GO_REF:0000019, GO:0007275=GO_REF:0000029, GO:0009954=GO_REF:0000019, GO:0005634=GO_REF:0000029, GO:0000122=GO_REF:0000019, GO:0003677=GO_REF:0000029, GO:0043565=GO_REF:0000002, GO:0021766=GO_REF:0000019, GO:0043524=GO_REF:0000019, GO:0003682=GO_REF:0000019, GO:0048715=GO_REF:0000019, GO:0042475=GO_REF:0000019, GO:0021893=GO_REF:0000019, GO:0021882=GO_REF:0000019} P56177 Homeobox protein DLX-1 protein 20021104 {GO:0000976=IEA, GO:0003700=IEA, GO:0048706=IEA, GO:0007275=NAS, GO:0009954=IEA, GO:0005634=NAS, GO:0000122=IEA, GO:0003677=NAS, GO:0043565=IEA, GO:0021766=IEA, GO:0043524=IEA, GO:0003682=IEA, GO:0048715=IEA, GO:0042475=IEA, GO:0021893=IEA, GO:0021882=IEA} cerebral cortex GABAergic interneuron fate commitment, embryonic skeletal system development, hippocampus development, multicellular organismal development, negative regulation of neuron apoptotic process, negative regulation of oligodendrocyte differentiation, negative regulation of transcription from RNA polymerase II promoter, odontogenesis of dentin-containing tooth, proximal/distal pattern formation, regulation of transcription from RNA polymerase II promoter involved in forebrain neuron fate commitment nucleus DNA binding, chromatin binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, transcription regulatory region sequence-specific DNA binding Human DLX2 PINC UniProtKB {GO:0000976=GO_REF:0000002, GO:0003727=GO_REF:0000019, GO:0003700=GO_REF:0000002, GO:0051216=GO_REF:0000019, GO:0005634=GO_REF:0000039, GO:0009954=GO_REF:0000019, GO:0000122=GO_REF:0000019, GO:0048701=GO_REF:0000019, GO:0043565=GO_REF:0000002, GO:0021766=GO_REF:0000019, GO:0021772=GO_REF:0000019, GO:0007420=PMID:7590232, GO:0045944=GO_REF:0000019, GO:0003682=GO_REF:0000019, GO:0048715=GO_REF:0000019, GO:0042475=GO_REF:0000019, GO:0048755=GO_REF:0000019, GO:0021893=GO_REF:0000019, GO:0021882=GO_REF:0000019} Q07687 Homeobox protein DLX-2 protein 20030904 {GO:0000976=IEA, GO:0003727=IEA, GO:0003700=IEA, GO:0051216=IEA, GO:0005634=IEA, GO:0009954=IEA, GO:0000122=IEA, GO:0048701=IEA, GO:0043565=IEA, GO:0021766=IEA, GO:0021772=IEA, GO:0007420=TAS, GO:0045944=IEA, GO:0003682=IEA, GO:0048715=IEA, GO:0042475=IEA, GO:0048755=IEA, GO:0021893=IEA, GO:0021882=IEA} brain development, branching morphogenesis of a nerve, cartilage development, cerebral cortex GABAergic interneuron fate commitment, embryonic cranial skeleton morphogenesis, hippocampus development, negative regulation of oligodendrocyte differentiation, negative regulation of transcription from RNA polymerase II promoter, odontogenesis of dentin-containing tooth, olfactory bulb development, positive regulation of transcription from RNA polymerase II promoter, proximal/distal pattern formation, regulation of transcription from RNA polymerase II promoter involved in forebrain neuron fate commitment nucleus chromatin binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, single-stranded RNA binding, transcription regulatory region sequence-specific DNA binding Human DLX3 UniProtKB UniProtKB {GO:0000976=GO_REF:0000002, GO:0001568=GO_REF:0000019, GO:0003700=GO_REF:0000002, GO:0005634=GO_REF:0000039, GO:0001890=GO_REF:0000019} O60479 Homeobox protein DLX-3 protein 20130413 {GO:0000976=IEA, GO:0001568=IEA, GO:0003700=IEA, GO:0005634=IEA, GO:0001890=IEA} blood vessel development, placenta development nucleus sequence-specific DNA binding transcription factor activity, transcription regulatory region sequence-specific DNA binding Human UniProtKB-SubCell:SL-0191 DLX4 IntAct UniProtKB {GO:0005515=PMID:21297662, GO:0043565=PMID:9073066, GO:0006355=PMID:11069021, GO:0000976=GO_REF:0000002, GO:0003700=PMID:11069021, GO:0005634=PMID:11069021, GO:0007275=GO_REF:0000037} Q92988 Homeobox protein DLX-4 protein 20130415 {GO:0005515=IPI, GO:0043565=IDA, GO:0006355=NAS, GO:0000976=IEA, GO:0003700=NAS, GO:0005634=NAS, GO:0007275=IEA} multicellular organismal development, regulation of transcription, DNA-dependent nucleus protein binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, transcription regulatory region sequence-specific DNA binding Human UniProtKB:Q13485 DLX5 HPA UniProtKB {GO:0071773=GO_REF:0000024, GO:0000790=GO_REF:0000024, GO:0044212=PMID:19497851, GO:0008283=PMID:19497851, GO:0090263=GO_REF:0000019, GO:0005634=GO_REF:0000052, GO:0030326=GO_REF:0000019, GO:0005737=GO_REF:0000019, GO:0048646=GO_REF:0000019, GO:0007411=GO_REF:0000019, GO:0030855=GO_REF:0000019, GO:0060166=GO_REF:0000019, GO:0060021=GO_REF:0000019, GO:1901522=GO_REF:0000024, GO:0050679=GO_REF:0000019, GO:0042472=GO_REF:0000019, GO:0005730=GO_REF:0000052, GO:0030509=GO_REF:0000024, GO:0000978=GO_REF:0000024, GO:0001649=GO_REF:0000024, GO:0007399=PMID:7907794, GO:0045669=GO_REF:0000019, GO:0001958=GO_REF:0000024, GO:0001501=PMID:7907794, GO:0001077=GO_REF:0000024, GO:0060325=GO_REF:0000019, GO:0071837=GO_REF:0000019, GO:0045893=PMID:19497851} P56178 Homeobox protein DLX-5 protein 20080818 {GO:0071773=ISS, GO:0000790=ISS, GO:0044212=IDA, GO:0008283=IDA, GO:0090263=IEA, GO:0005634=IDA, GO:0030326=IEA, GO:0005737=IEA, GO:0048646=IEA, GO:0007411=IEA, GO:0030855=IEA, GO:0060166=IEA, GO:0060021=IEA, GO:1901522=ISS, GO:0050679=IEA, GO:0042472=IEA, GO:0005730=IDA, GO:0030509=ISS, GO:0000978=ISS, GO:0001649=ISS, GO:0007399=TAS, GO:0045669=IEA, GO:0001958=ISS, GO:0001501=TAS, GO:0001077=ISS, GO:0060325=IEA, GO:0071837=IEA, GO:0045893=IDA} BMP signaling pathway, anatomical structure formation involved in morphogenesis, axon guidance, cell proliferation, cellular response to BMP stimulus, embryonic limb morphogenesis, endochondral ossification, epithelial cell differentiation, face morphogenesis, inner ear morphogenesis, nervous system development, olfactory pit development, osteoblast differentiation, palate development, positive regulation of canonical Wnt receptor signaling pathway, positive regulation of epithelial cell proliferation, positive regulation of osteoblast differentiation, positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus, positive regulation of transcription, DNA-dependent, skeletal system development cytoplasm, nuclear chromatin, nucleolus, nucleus HMG box domain binding, RNA polymerase II core promoter proximal region sequence-specific DNA binding, RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription, transcription regulatory region DNA binding NOT Human DLX6 PINC UniProtKB {GO:0050679=GO_REF:0000019, GO:0001501=PMID:7907794, GO:0000976=GO_REF:0000002, GO:0048646=GO_REF:0000019, GO:0042472=GO_REF:0000019, GO:0003700=GO_REF:0000002, GO:0030855=GO_REF:0000019, GO:0060322=GO_REF:0000019, GO:0060021=GO_REF:0000019, GO:0005634=GO_REF:0000039, GO:0030326=GO_REF:0000019, GO:0007399=PMID:7907794} P56179 Homeobox protein DLX-6 protein 20030904 {GO:0050679=IEA, GO:0001501=TAS, GO:0000976=IEA, GO:0048646=IEA, GO:0042472=IEA, GO:0003700=IEA, GO:0030855=IEA, GO:0060322=IEA, GO:0060021=IEA, GO:0005634=IEA, GO:0030326=IEA, GO:0007399=TAS} anatomical structure formation involved in morphogenesis, embryonic limb morphogenesis, epithelial cell differentiation, head development, inner ear morphogenesis, nervous system development, palate development, positive regulation of epithelial cell proliferation, skeletal system development nucleus sequence-specific DNA binding transcription factor activity, transcription regulatory region sequence-specific DNA binding Human DMAP1 UniProtKB UniProtKB {GO:0005515=PMID:15367675, GO:0001103=PMID:15367675, GO:0003714=GO_REF:0000019, GO:0005657=GO_REF:0000019, GO:0005634=PMID:15367675, GO:0000122=PMID:15367675, GO:0042993=PMID:15367675, GO:0006351=GO_REF:0000037, GO:0006306=PMID:10888872, GO:0005737=PMID:15367675, GO:0006281=GO_REF:0000002, GO:0043967=PMID:14966270, GO:0043968=PMID:14966270, GO:0003682=GO_REF:0000002, GO:0035267=PMID:14966270, GO:0006338=GO_REF:0000002, GO:0045892=PMID:10888872, GO:0040008=GO_REF:0000037} Q9NPF5 DNA methyltransferase 1-associated protein 1 protein 20111214 {GO:0005515=IPI, GO:0001103=IDA, GO:0003714=IEA, GO:0005657=IEA, GO:0005634=IDA, GO:0000122=IDA, GO:0042993=IDA, GO:0006351=IEA, GO:0006306=TAS, GO:0005737=IDA, GO:0006281=IEA, GO:0043967=IDA, GO:0043968=IDA, GO:0003682=IEA, GO:0035267=IDA, GO:0006338=IEA, GO:0045892=NAS, GO:0040008=IEA} DNA methylation, DNA repair, chromatin remodeling, histone H2A acetylation, histone H4 acetylation, negative regulation of transcription from RNA polymerase II promoter, negative regulation of transcription, DNA-dependent, positive regulation of transcription factor import into nucleus, regulation of growth, transcription, DNA-dependent NuA4 histone acetyltransferase complex, cytoplasm, nucleus, replication fork RNA polymerase II repressing transcription factor binding, chromatin binding, protein binding, transcription corepressor activity Human DMBT1 GOC UniProtKB {GO:0005515=PMID:14676191, GO:0001833=GO_REF:0000019, GO:0005578=GO_REF:0000019, GO:0005576=PMID:14732920, GO:0015031=GO_REF:0000037, GO:0035375=GO_REF:0000024, GO:0051636=GO_REF:0000024, GO:0002221=PMID:12681477, GO:0005737=PMID:10485905, GO:0051607=GO_REF:0000037, GO:0030858=GO_REF:0000019, GO:0042589=GO_REF:0000024, GO:0016020=GO_REF:0000002, GO:0019048=GO_REF:0000037, GO:0045087=PMID:10485905, GO:0051637=GO_REF:0000024, GO:0030855=PMID:14732920, GO:0030670=PMID:10485905, GO:0043152=PMID:14732920, GO:0019898=GO_REF:0000024, GO:0008329=PMID:12681477, GO:0005044=PMID:9288095, GO:0048306=PMID:10485905} Q9UGM3 Deleted in malignant brain tumors 1 protein protein 20130413 {GO:0005515=IPI, GO:0001833=IEA, GO:0005578=IEA, GO:0005576=TAS, GO:0015031=IEA, GO:0035375=ISS, GO:0051636=ISS, GO:0002221=TAS, GO:0005737=IDA, GO:0051607=IEA, GO:0030858=IEA, GO:0042589=ISS, GO:0016020=IEA, GO:0019048=IEA, GO:0045087=TAS, GO:0051637=ISS, GO:0030855=TAS, GO:0030670=IDA, GO:0043152=TAS, GO:0019898=ISS, GO:0008329=TAS, GO:0005044=NAS, GO:0048306=TAS} defense response to virus, epithelial cell differentiation, induction of bacterial agglutination, innate immune response, inner cell mass cell proliferation, pattern recognition receptor signaling pathway, positive regulation of epithelial cell differentiation, protein transport, virus-host interaction cytoplasm, extracellular region, extrinsic to membrane, membrane, phagocytic vesicle membrane, proteinaceous extracellular matrix, zymogen granule membrane Gram-negative bacterial cell surface binding, Gram-positive bacterial cell surface binding, calcium-dependent protein binding, pattern recognition receptor activity, protein binding, scavenger receptor activity, zymogen binding Human DMBX1 UniProtKB UniProtKB {GO:0008343=GO_REF:0000019, GO:0005667=GO_REF:0000019, GO:0008344=GO_REF:0000019, GO:0003700=GO_REF:0000024, GO:0046982=GO_REF:0000019, GO:0000122=GO_REF:0000019, GO:0007417=GO_REF:0000024, GO:0003677=GO_REF:0000024, GO:0006351=GO_REF:0000037, GO:0042803=GO_REF:0000019, GO:0043565=GO_REF:0000024, GO:0048589=GO_REF:0000024, GO:0007420=GO_REF:0000024, GO:0045892=GO_REF:0000024} Q8NFW5 Diencephalon/mesencephalon homeobox protein 1 protein 20061106 {GO:0008343=IEA, GO:0005667=IEA, GO:0008344=IEA, GO:0003700=ISS, GO:0046982=IEA, GO:0000122=IEA, GO:0007417=ISS, GO:0003677=ISS, GO:0006351=IEA, GO:0042803=IEA, GO:0043565=ISS, GO:0048589=ISS, GO:0007420=ISS, GO:0045892=ISS} adult feeding behavior, adult locomotory behavior, brain development, central nervous system development, developmental growth, negative regulation of transcription from RNA polymerase II promoter, negative regulation of transcription, DNA-dependent, transcription, DNA-dependent transcription factor complex DNA binding, protein heterodimerization activity, protein homodimerization activity, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity Human UniProtKB:Q91ZK4 DMC1 PINC UniProtKB {GO:0005515=PMID:20729832, GO:0000781=GO_REF:0000019, GO:0000794=GO_REF:0000019, GO:0000239=GO_REF:0000019, GO:0005694=GO_REF:0000024, GO:0007286=GO_REF:0000019, GO:0007292=PMID:8602360, GO:0007283=PMID:8590282, GO:0006259=GO_REF:0000002, GO:0001556=GO_REF:0000019, GO:0003677=GO_REF:0000037, GO:0005524=GO_REF:0000037, GO:0001541=GO_REF:0000019, GO:0007126=PMID:8602360, GO:0007141=GO_REF:0000019, GO:0008094=GO_REF:0000002, GO:0007131=GO_REF:0000002} Q14565 Meiotic recombination protein DMC1/LIM15 homolog protein 20030904 {GO:0005515=IPI, GO:0000781=IEA, GO:0000794=IEA, GO:0000239=IEA, GO:0005694=ISS, GO:0007286=IEA, GO:0007292=TAS, GO:0007283=TAS, GO:0006259=IEA, GO:0001556=IEA, GO:0003677=IEA, GO:0005524=IEA, GO:0001541=IEA, GO:0007126=TAS, GO:0007141=IEA, GO:0008094=IEA, GO:0007131=IEA} DNA metabolic process, female gamete generation, male meiosis I, meiosis, oocyte maturation, ovarian follicle development, pachytene, reciprocal meiotic recombination, spermatid development, spermatogenesis chromosome, chromosome, telomeric region, condensed nuclear chromosome ATP binding, DNA binding, DNA-dependent ATPase activity, protein binding Human DMD UniProtKB UniProtKB {GO:0050998=PMID:7545544, GO:0005515=PMID:16000376, GO:0030055=GO_REF:0000019, GO:0030018=GO_REF:0000019, GO:0002162=PMID:7592992, GO:0045202=GO_REF:0000019, GO:0060857=GO_REF:0000019, GO:0014819=PMID:19198614, GO:0060048=PMID:19027585, GO:0046716=GO_REF:0000019, GO:0005829=Reactome:REACT_17057, GO:0021629=GO_REF:0000019, GO:0048747=GO_REF:0000019, GO:0016010=PMID:17993586, GO:0045211=GO_REF:0000039, GO:0086001=PMID:20080623, GO:0005856=GO_REF:0000039, GO:0008307=PMID:16000376, GO:0051647=GO_REF:0000019, GO:0044306=GO_REF:0000019, GO:0006355=GO_REF:0000019, GO:0030049=Reactome:REACT_16969, GO:0009986=PMID:10867799, GO:0005509=GO_REF:0000002, GO:0043043=PMID:16000376, GO:0010881=PMID:20080623, GO:0003779=GO_REF:0000038, GO:0045213=GO_REF:0000019, GO:0014904=GO_REF:0000019, GO:0014809=PMID:19198614, GO:0042383=PMID:7545544, GO:0043234=PMID:18468998, GO:0007517=PMID:1824797, GO:0002027=PMID:19027585, GO:0008065=GO_REF:0000019, GO:0005200=PMID:3282674, GO:0043034=PMID:16000376, GO:0045121=GO_REF:0000019, GO:0008270=GO_REF:0000002} Q4G0X0 Dystrophin protein 20130413 {GO:0050998=ISS, GO:0005515=IPI, GO:0030055=IEA, GO:0030018=IEA, GO:0002162=IPI, GO:0045202=IEA, GO:0060857=IEA, GO:0014819=ISS, GO:0060048=IMP, GO:0046716=IEA, GO:0005829=TAS, GO:0021629=IEA, GO:0048747=IEA, GO:0016010=IDA, GO:0045211=IEA, GO:0086001=ISS, GO:0005856=IEA, GO:0008307=IDA, GO:0051647=IEA, GO:0044306=IEA, GO:0006355=IEA, GO:0030049=TAS, GO:0009986=IDA, GO:0005509=IEA, GO:0043043=IDA, GO:0010881=ISS, GO:0003779=IEA, GO:0045213=IEA, GO:0014904=IEA, GO:0014809=ISS, GO:0042383=IDA, GO:0043234=IDA, GO:0007517=NAS, GO:0002027=IMP, GO:0008065=IEA, GO:0005200=TAS, GO:0043034=IDA, GO:0045121=IEA, GO:0008270=IEA} cardiac muscle contraction, establishment of blood-nerve barrier, establishment of glial blood-brain barrier, muscle cell homeostasis, muscle fiber development, muscle filament sliding, muscle organ development, myotube cell development, neurotransmitter receptor metabolic process, nucleus localization, olfactory nerve structural organization, peptide biosynthetic process, regulation of cardiac muscle cell action potential, regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion, regulation of heart rate, regulation of skeletal muscle contraction, regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion, regulation of transcription, DNA-dependent Z disc, cell surface, cell-substrate junction, costamere, cytoskeleton, cytosol, dystrophin-associated glycoprotein complex, membrane raft, neuron projection terminus, postsynaptic membrane, protein complex, sarcolemma, synapse actin binding, calcium ion binding, dystroglycan binding, nitric-oxide synthase binding, protein binding, structural constituent of cytoskeleton, structural constituent of muscle, zinc ion binding Human UniProtKB-KW:KW-0009 DMKN ENSEMBL UniProtKB {GO:0005615=GO_REF:0000019} Q6E0U4 Dermokine protein 20130413 {GO:0005615=IEA} extracellular space Human Ensembl:ENSMUSP00000129031 DMP1 HPA UniProtKB {GO:0005737=GO_REF:0000039, GO:0005178=PMID:8509401, GO:0001503=GO_REF:0000002, GO:0030198=GO_REF:0000019, GO:0005509=PMID:8509401, GO:0010811=GO_REF:0000019, GO:0005730=GO_REF:0000052, GO:0005578=GO_REF:0000039, GO:0050840=GO_REF:0000019, GO:0005634=GO_REF:0000052, GO:0031214=GO_REF:0000037, GO:0043231=GO_REF:0000052} Q13316 Dentin matrix acidic phosphoprotein 1 protein 20110516 {GO:0005737=IEA, GO:0005178=TAS, GO:0001503=IEA, GO:0030198=IEA, GO:0005509=TAS, GO:0010811=IEA, GO:0005730=IDA, GO:0005578=IEA, GO:0050840=IEA, GO:0005634=IDA, GO:0031214=IEA, GO:0043231=IDA} biomineral tissue development, extracellular matrix organization, ossification, positive regulation of cell-substrate adhesion cytoplasm, intracellular membrane-bounded organelle, nucleolus, nucleus, proteinaceous extracellular matrix calcium ion binding, extracellular matrix binding, integrin binding Human DMPK IntAct UniProtKB {GO:0005515=PMID:15598648, GO:0031965=GO_REF:0000024, GO:0005886=GO_REF:0000024, GO:0031532=GO_REF:0000002, GO:0008016=PMID:15598648, GO:0006874=GO_REF:0000024, GO:0033017=GO_REF:0000024, GO:0010830=GO_REF:0000024, GO:0005524=PMID:10913253, GO:0046872=GO_REF:0000037, GO:0005829=GO_REF:0000024, GO:0014722=GO_REF:0000019, GO:0005640=GO_REF:0000039, GO:0051823=GO_REF:0000019, GO:0004672=GO_REF:0000002, GO:0017020=PMID:11287000, GO:0004674=PMID:11287000, GO:0002028=GO_REF:0000019, GO:0005789=GO_REF:0000024, GO:0010657=PMID:18729234, GO:0006998=PMID:21949239, GO:0006468=PMID:11287000, GO:0031307=PMID:15684391, GO:0014853=GO_REF:0000019} Q09013 Myotonin-protein kinase protein 20130415 {GO:0005515=IPI, GO:0031965=ISS, GO:0005886=ISS, GO:0031532=IEA, GO:0008016=IDA, GO:0006874=ISS, GO:0033017=ISS, GO:0010830=ISS, GO:0005524=IDA, GO:0046872=IEA, GO:0005829=ISS, GO:0014722=IEA, GO:0005640=IEA, GO:0051823=IEA, GO:0004672=IEA, GO:0017020=IDA, GO:0004674=IDA, GO:0002028=IEA, GO:0005789=ISS, GO:0010657=IDA, GO:0006998=IMP, GO:0006468=IDA, GO:0031307=IDA, GO:0014853=IEA} actin cytoskeleton reorganization, cellular calcium ion homeostasis, muscle cell apoptotic process, nuclear envelope organization, protein phosphorylation, regulation of excitatory postsynaptic membrane potential involved in skeletal muscle contraction, regulation of heart contraction, regulation of myotube differentiation, regulation of skeletal muscle contraction by calcium ion signaling, regulation of sodium ion transport, regulation of synapse structural plasticity cytosol, endoplasmic reticulum membrane, integral to mitochondrial outer membrane, nuclear membrane, nuclear outer membrane, plasma membrane, sarcoplasmic reticulum membrane ATP binding, metal ion binding, myosin phosphatase regulator activity, protein binding, protein kinase activity, protein serine/threonine kinase activity Human UniProtKB:P26678 DMRT1 PINC UniProtKB {GO:0000987=GO_REF:0000024, GO:0008354=GO_REF:0000019, GO:0003700=PMID:10332030, GO:0046661=GO_REF:0000024, GO:0002176=GO_REF:0000024, GO:0005634=GO_REF:0000024, GO:0045840=GO_REF:0000024, GO:0000122=GO_REF:0000024, GO:0007283=GO_REF:0000019, GO:0046872=GO_REF:0000037, GO:0006351=GO_REF:0000037, GO:0007530=PMID:10332030, GO:0035556=GO_REF:0000019, GO:0000902=GO_REF:0000019, GO:0060008=GO_REF:0000024, GO:0030238=GO_REF:0000024, GO:0045944=GO_REF:0000024, GO:0045835=GO_REF:0000024, GO:0008584=PMID:10332030} Q9Y5R6 Doublesex- and mab-3-related transcription factor 1 protein 20030904 {GO:0000987=ISS, GO:0008354=IEA, GO:0003700=TAS, GO:0046661=ISS, GO:0002176=ISS, GO:0005634=ISS, GO:0045840=ISS, GO:0000122=ISS, GO:0007283=IEA, GO:0046872=IEA, GO:0006351=IEA, GO:0007530=TAS, GO:0035556=IEA, GO:0000902=IEA, GO:0060008=ISS, GO:0030238=ISS, GO:0045944=ISS, GO:0045835=ISS, GO:0008584=TAS} Sertoli cell differentiation, cell morphogenesis, germ cell migration, intracellular signal transduction, male germ cell proliferation, male gonad development, male sex determination, male sex differentiation, negative regulation of meiosis, negative regulation of transcription from RNA polymerase II promoter, positive regulation of mitosis, positive regulation of transcription from RNA polymerase II promoter, sex determination, spermatogenesis, transcription, DNA-dependent nucleus core promoter proximal region sequence-specific DNA binding, metal ion binding, sequence-specific DNA binding transcription factor activity Human DMRT2 PINC UniProtKB {GO:0043565=GO_REF:0000002, GO:0003674=GO_REF:0000015, GO:0008150=GO_REF:0000015, GO:0003700=PMID:10332030, GO:0005634=GO_REF:0000039, GO:0005575=GO_REF:0000015, GO:0008584=PMID:10332030, GO:0046872=GO_REF:0000037, GO:0006351=GO_REF:0000037, GO:0007530=PMID:10332030} Q9Y5R5 Doublesex- and mab-3-related transcription factor 2 protein 20030904 {GO:0043565=IEA, GO:0003674=ND, GO:0008150=ND, GO:0003700=TAS, GO:0005634=IEA, GO:0005575=ND, GO:0008584=TAS, GO:0046872=IEA, GO:0006351=IEA, GO:0007530=TAS} biological_process, male gonad development, sex determination, transcription, DNA-dependent cellular_component, nucleus metal ion binding, molecular_function, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity Human DMRTA1 UniProtKB UniProtKB {GO:0043565=GO_REF:0000002, GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0007548=GO_REF:0000002, GO:0046872=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q5VZB9 Doublesex- and mab-3-related transcription factor A1 protein 20130413 {GO:0043565=IEA, GO:0006355=IEA, GO:0005634=IEA, GO:0007548=IEA, GO:0046872=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, sex differentiation, transcription, DNA-dependent nucleus metal ion binding, sequence-specific DNA binding Human UniProtKB-SubCell:SL-0191 DMRTB1 UniProtKB UniProtKB {GO:0043565=GO_REF:0000002, GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0007548=GO_REF:0000002, GO:0046872=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q96MA1 Doublesex- and mab-3-related transcription factor B1 protein 20130413 {GO:0043565=IEA, GO:0006355=IEA, GO:0005634=IEA, GO:0007548=IEA, GO:0046872=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, sex differentiation, transcription, DNA-dependent nucleus metal ion binding, sequence-specific DNA binding Human UniProtKB-SubCell:SL-0191 DMRTC2 UniProtKB UniProtKB {GO:0043565=GO_REF:0000002, GO:0006355=GO_REF:0000037, GO:0007548=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0046872=GO_REF:0000037, GO:0030154=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q8IXT2 Doublesex- and mab-3-related transcription factor C2 protein 20130413 {GO:0043565=IEA, GO:0006355=IEA, GO:0007548=IEA, GO:0005634=IEA, GO:0046872=IEA, GO:0030154=IEA, GO:0006351=IEA} cell differentiation, regulation of transcription, DNA-dependent, sex differentiation, transcription, DNA-dependent nucleus metal ion binding, sequence-specific DNA binding Human UniProtKB-SubCell:SL-0191 DMTF1 HPA UniProtKB {GO:0006355=PMID:10095122, GO:0007049=GO_REF:0000037, GO:0005737=GO_REF:0000052, GO:0003700=PMID:10095122, GO:0003682=GO_REF:0000002, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q9Y222 Cyclin-D-binding Myb-like transcription factor 1 protein 20100326 {GO:0006355=NAS, GO:0007049=IEA, GO:0005737=IDA, GO:0003700=NAS, GO:0003682=IEA, GO:0005730=IDA, GO:0005634=IDA, GO:0003677=IEA, GO:0006351=IEA} cell cycle, regulation of transcription, DNA-dependent, transcription, DNA-dependent cytoplasm, nucleolus, nucleus DNA binding, chromatin binding, sequence-specific DNA binding transcription factor activity Human DMWD UniProtKB UniProtKB {GO:0003674=GO_REF:0000015, GO:0007126=GO_REF:0000029, GO:0005575=GO_REF:0000015} Q09019 Dystrophia myotonica WD repeat-containing protein protein 20061026 {GO:0003674=ND, GO:0007126=NAS, GO:0005575=ND} meiosis cellular_component molecular_function Human DMXL1 null null {} null null null null {} null null null DMXL2 MGI UniProtKB {GO:0017137=PMID:11809763, GO:0030054=GO_REF:0000037, GO:0030672=GO_REF:0000039, GO:0008021=PMID:11809763} Q8TDJ6 DmX-like protein 2 protein 20060111 {GO:0017137=IDA, GO:0030054=IEA, GO:0030672=IEA, GO:0008021=IDA} cell junction, synaptic vesicle, synaptic vesicle membrane Rab GTPase binding Human DNA2 GOC UniProtKB {GO:0042645=PMID:19487465, GO:0005515=PMID:21325134, GO:0006200=PMID:18995831, GO:0016890=PMID:18995831, GO:0005760=PMID:18995831, GO:0033567=PMID:22570407, GO:0005634=PMID:19487465, GO:0046872=GO_REF:0000037, GO:0000084=Reactome:REACT_899, GO:0006271=Reactome:REACT_932, GO:0000723=Reactome:REACT_7970, GO:0000722=Reactome:REACT_8027, GO:0043504=PMID:19487465, GO:0032508=PMID:16595800, GO:0016887=PMID:18995831, GO:0000729=PMID:21325134, GO:0043142=PMID:16595800, GO:0051539=GO_REF:0000037, GO:0045740=PMID:18995831, GO:0004386=PMID:18995831, GO:0005524=GO_REF:0000037, GO:0003677=PMID:20019387, GO:0003678=PMID:16595800, GO:0006260=PMID:22570476, GO:0004518=PMID:21325134, GO:0006284=PMID:18995831, GO:0000076=PMID:22570476, GO:0043139=PMID:20019387, GO:0005654=Reactome:REACT_8015, GO:0043137=PMID:18995831, GO:0017108=PMID:20019387, GO:0000278=Reactome:REACT_152, GO:0006264=PMID:19487465, GO:0032201=Reactome:REACT_7961} P51530 DNA replication ATP-dependent helicase/nuclease DNA2 protein 20130413 {GO:0042645=IDA, GO:0005515=IPI, GO:0006200=TAS, GO:0016890=IDA, GO:0005760=IDA, GO:0033567=IDA, GO:0005634=IDA, GO:0046872=IEA, GO:0000084=TAS, GO:0006271=TAS, GO:0000723=TAS, GO:0000722=TAS, GO:0043504=IDA, GO:0032508=IDA, GO:0016887=TAS, GO:0000729=IDA, GO:0043142=IDA, GO:0051539=IEA, GO:0045740=IDA, GO:0004386=TAS, GO:0005524=IEA, GO:0003677=IDA, GO:0003678=IDA, GO:0006260=IMP, GO:0004518=IDA, GO:0006284=IDA, GO:0000076=IMP, GO:0043139=IDA, GO:0005654=TAS, GO:0043137=IDA, GO:0017108=IDA, GO:0000278=TAS, GO:0006264=IDA, GO:0032201=TAS} ATP catabolic process, DNA double-strand break processing, DNA duplex unwinding, DNA replication, DNA replication checkpoint, DNA replication, Okazaki fragment processing, DNA replication, removal of RNA primer, DNA strand elongation involved in DNA replication, S phase of mitotic cell cycle, base-excision repair, mitochondrial DNA repair, mitochondrial DNA replication, mitotic cell cycle, positive regulation of DNA replication, telomere maintenance, telomere maintenance via recombination, telomere maintenance via semi-conservative replication gamma DNA polymerase complex, mitochondrial nucleoid, nucleoplasm, nucleus 4 iron, 4 sulfur cluster binding, 5'-3' DNA helicase activity, 5'-flap endonuclease activity, ATP binding, ATPase activity, DNA binding, DNA helicase activity, helicase activity, metal ion binding, nuclease activity, protein binding, single-stranded DNA-dependent ATPase activity, site-specific endodeoxyribonuclease activity, specific for altered base Human DNAAF1 HPA UniProtKB {GO:0036159=PMID:19944400, GO:0003356=PMID:19944400, GO:0035469=PMID:19944405, GO:0005886=GO_REF:0000052, GO:0030324=PMID:19944405, GO:0071910=PMID:19944405, GO:0005634=GO_REF:0000052, GO:0003341=PMID:19944405, GO:0035085=PMID:18385425, GO:0070286=PMID:19944400, GO:0044458=PMID:19944405, GO:0060287=PMID:19944405, GO:0001947=PMID:19944405, GO:0005737=GO_REF:0000052, GO:0000922=GO_REF:0000039, GO:0045502=PMID:18385425, GO:0060972=PMID:19944400, GO:0060271=PMID:18385425, GO:0036158=PMID:19944400, GO:0071907=PMID:19944405} Q8NEP3 Dynein assembly factor 1, axonemal protein 20111111 {GO:0036159=IMP, GO:0003356=IMP, GO:0035469=IMP, GO:0005886=IDA, GO:0030324=IMP, GO:0071910=IMP, GO:0005634=IDA, GO:0003341=IMP, GO:0035085=IDA, GO:0070286=IMP, GO:0044458=IMP, GO:0060287=IC, GO:0001947=IMP, GO:0005737=IDA, GO:0000922=IEA, GO:0045502=IMP, GO:0060972=IMP, GO:0060271=IMP, GO:0036158=IMP, GO:0071907=IMP} axonemal dynein complex assembly, cilium morphogenesis, cilium movement, determination of digestive tract left/right asymmetry, determination of liver left/right asymmetry, determination of pancreatic left/right asymmetry, epithelial cilium movement involved in determination of left/right asymmetry, heart looping, inner dynein arm assembly, left/right pattern formation, lung development, motile cilium assembly, outer dynein arm assembly, regulation of cilium beat frequency cilium axoneme, cytoplasm, nucleus, plasma membrane, spindle pole dynein binding Human DNAAF2 UniProtKB UniProtKB {GO:0060286=PMID:19052621, GO:0005737=PMID:19052621, GO:0060285=PMID:19052621, GO:0032526=GO_REF:0000019, GO:0070286=PMID:19052621} Q9NVR5 Protein kintoun protein 20090330 {GO:0060286=IMP, GO:0005737=IDA, GO:0060285=IMP, GO:0032526=IEA, GO:0070286=IMP} axonemal dynein complex assembly, ciliary cell motility, flagellar cell motility, response to retinoic acid cytoplasm Human DNAH1 UniProtKB UniProtKB {GO:0030286=PMID:8812413, GO:0001539=PMID:9373155, GO:0005874=GO_REF:0000037, GO:0005858=PMID:9373155, GO:0035085=GO_REF:0000039, GO:0003777=PMID:9373155, GO:0005524=GO_REF:0000037, GO:0016887=GO_REF:0000002, GO:0009612=PMID:8812413, GO:0007018=GO_REF:0000019} Q9P2D7 Dynein heavy chain 1, axonemal protein 20090811 {GO:0030286=NAS, GO:0001539=NAS, GO:0005874=IEA, GO:0005858=NAS, GO:0035085=IEA, GO:0003777=NAS, GO:0005524=IEA, GO:0016887=IEA, GO:0009612=NAS, GO:0007018=IEA} ciliary or flagellar motility, microtubule-based movement, response to mechanical stimulus axonemal dynein complex, cilium axoneme, dynein complex, microtubule ATP binding, ATPase activity, microtubule motor activity Human DNAH11 UniProtKB UniProtKB {GO:0007368=GO_REF:0000019, GO:0001539=GO_REF:0000019, GO:0005874=GO_REF:0000037, GO:0005858=GO_REF:0000029, GO:0035085=GO_REF:0000039, GO:0003777=GO_REF:0000029, GO:0005524=GO_REF:0000037, GO:0016887=GO_REF:0000002, GO:0007018=GO_REF:0000002} Q96DT5 Dynein heavy chain 11, axonemal protein 20031120 {GO:0007368=IEA, GO:0001539=IEA, GO:0005874=IEA, GO:0005858=NAS, GO:0035085=IEA, GO:0003777=NAS, GO:0005524=IEA, GO:0016887=IEA, GO:0007018=IEA} ciliary or flagellar motility, determination of left/right symmetry, microtubule-based movement axonemal dynein complex, cilium axoneme, microtubule ATP binding, ATPase activity, microtubule motor activity Human DNAH14 UniProtKB UniProtKB {GO:0030286=GO_REF:0000037, GO:0005874=GO_REF:0000037, GO:0035085=GO_REF:0000039, GO:0003777=GO_REF:0000002, GO:0005524=GO_REF:0000037, GO:0007018=GO_REF:0000002} Q0VDD8 Dynein heavy chain 14, axonemal protein 20130413 {GO:0030286=IEA, GO:0005874=IEA, GO:0035085=IEA, GO:0003777=IEA, GO:0005524=IEA, GO:0007018=IEA} microtubule-based movement cilium axoneme, dynein complex, microtubule ATP binding, microtubule motor activity Human UniProtKB-SubCell:SL-0304 DNAH2 UniProtKB UniProtKB {GO:0001539=PMID:9256245, GO:0005874=GO_REF:0000037, GO:0005858=PMID:9256245, GO:0035085=GO_REF:0000039, GO:0003777=PMID:9256245, GO:0005524=GO_REF:0000037, GO:0016887=GO_REF:0000002, GO:0007018=GO_REF:0000002} Q9P225 Dynein heavy chain 2, axonemal protein 20010911 {GO:0001539=NAS, GO:0005874=IEA, GO:0005858=NAS, GO:0035085=IEA, GO:0003777=NAS, GO:0005524=IEA, GO:0016887=IEA, GO:0007018=IEA} ciliary or flagellar motility, microtubule-based movement axonemal dynein complex, cilium axoneme, microtubule ATP binding, ATPase activity, microtubule motor activity Human DNAH3 UniProtKB UniProtKB {GO:0001539=PMID:9256245, GO:0005874=GO_REF:0000037, GO:0005858=PMID:9256245, GO:0003777=PMID:9256245, GO:0035085=GO_REF:0000039, GO:0005524=GO_REF:0000037, GO:0016887=GO_REF:0000002, GO:0007018=GO_REF:0000002} Q8TD57 Dynein heavy chain 3, axonemal protein 20010911 {GO:0001539=NAS, GO:0005874=IEA, GO:0005858=NAS, GO:0003777=NAS, GO:0035085=IEA, GO:0005524=IEA, GO:0016887=IEA, GO:0007018=IEA} ciliary or flagellar motility, microtubule-based movement axonemal dynein complex, cilium axoneme, microtubule ATP binding, ATPase activity, microtubule motor activity Human DNAH5 UniProtKB UniProtKB {GO:0008150=GO_REF:0000015, GO:0001539=GO_REF:0000019, GO:0005874=GO_REF:0000037, GO:0005858=GO_REF:0000019, GO:0005575=GO_REF:0000015, GO:0003777=PMID:8812413, GO:0035085=GO_REF:0000039, GO:0005524=GO_REF:0000037, GO:0016887=GO_REF:0000002, GO:0007018=GO_REF:0000002} Q8TE73 Dynein heavy chain 5, axonemal protein 20061026 {GO:0008150=ND, GO:0001539=IEA, GO:0005874=IEA, GO:0005858=IEA, GO:0005575=ND, GO:0003777=NAS, GO:0035085=IEA, GO:0005524=IEA, GO:0016887=IEA, GO:0007018=IEA} biological_process, ciliary or flagellar motility, microtubule-based movement axonemal dynein complex, cellular_component, cilium axoneme, microtubule ATP binding, ATPase activity, microtubule motor activity Human DNAH6 UniProtKB UniProtKB {GO:0001539=GO_REF:0000002, GO:0005874=GO_REF:0000037, GO:0005858=GO_REF:0000002, GO:0003777=PMID:8812413, GO:0035085=GO_REF:0000039, GO:0005524=GO_REF:0000037, GO:0016887=GO_REF:0000002, GO:0007018=GO_REF:0000002} Q9C0G6 Dynein heavy chain 6, axonemal protein 20090811 {GO:0001539=IEA, GO:0005874=IEA, GO:0005858=IEA, GO:0003777=NAS, GO:0035085=IEA, GO:0005524=IEA, GO:0016887=IEA, GO:0007018=IEA} ciliary or flagellar motility, microtubule-based movement axonemal dynein complex, cilium axoneme, microtubule ATP binding, ATPase activity, microtubule motor activity Human DNAH7 MGI UniProtKB {GO:0005929=PMID:11877439, GO:0001539=PMID:9373155, GO:0005874=GO_REF:0000037, GO:0005509=GO_REF:0000002, GO:0005858=PMID:9373155, GO:0003777=PMID:9373155, GO:0035085=GO_REF:0000039, GO:0005524=GO_REF:0000037, GO:0016887=GO_REF:0000002, GO:0007018=GO_REF:0000002} Q8WXX0 Dynein heavy chain 7, axonemal protein 20060111 {GO:0005929=IDA, GO:0001539=NAS, GO:0005874=IEA, GO:0005509=IEA, GO:0005858=NAS, GO:0003777=NAS, GO:0035085=IEA, GO:0005524=IEA, GO:0016887=IEA, GO:0007018=IEA} ciliary or flagellar motility, microtubule-based movement axonemal dynein complex, cilium, cilium axoneme, microtubule ATP binding, ATPase activity, calcium ion binding, microtubule motor activity Human DNAH9 PINC UniProtKB {GO:0005874=GO_REF:0000037, GO:0006928=PMID:8812413, GO:0007283=PMID:8703119, GO:0003777=GO_REF:0000029, GO:0035085=PMID:11104725, GO:0005524=GO_REF:0000037, GO:0003774=PMID:8812413, GO:0030286=GO_REF:0000002, GO:0030030=GO_REF:0000037, GO:0005858=GO_REF:0000029, GO:0005856=PMID:8812413, GO:0016887=GO_REF:0000002, GO:0007018=GO_REF:0000002} Q9NYC9 Dynein heavy chain 9, axonemal protein 20030904 {GO:0005874=IEA, GO:0006928=TAS, GO:0007283=TAS, GO:0003777=NAS, GO:0035085=IDA, GO:0005524=IEA, GO:0003774=TAS, GO:0030286=IEA, GO:0030030=IEA, GO:0005858=NAS, GO:0005856=TAS, GO:0016887=IEA, GO:0007018=IEA} cell projection organization, cellular component movement, microtubule-based movement, spermatogenesis axonemal dynein complex, cilium axoneme, cytoskeleton, dynein complex, microtubule ATP binding, ATPase activity, microtubule motor activity, motor activity Human DNAI1 PINC UniProtKB {GO:0005929=PMID:10577904, GO:0003774=GO_REF:0000037, GO:0003351=GO_REF:0000019, GO:0030286=GO_REF:0000037, GO:0030030=GO_REF:0000037, GO:0005874=GO_REF:0000037, GO:0005856=PMID:10577904, GO:0035085=GO_REF:0000039} Q9UI46 Dynein intermediate chain 1, axonemal protein 20030904 {GO:0005929=TAS, GO:0003774=IEA, GO:0003351=IEA, GO:0030286=IEA, GO:0030030=IEA, GO:0005874=IEA, GO:0005856=TAS, GO:0035085=IEA} cell projection organization, epithelial cilium movement cilium, cilium axoneme, cytoskeleton, dynein complex, microtubule motor activity Human DNAJA1 PINC UniProtKB {GO:0006986=PMID:8334160, GO:0016020=GO_REF:0000039, GO:0009408=GO_REF:0000002, GO:0006457=GO_REF:0000002, GO:0031072=GO_REF:0000002, GO:0030317=GO_REF:0000019, GO:0007283=GO_REF:0000019, GO:0051082=GO_REF:0000002, GO:0005524=GO_REF:0000002, GO:0046872=GO_REF:0000037, GO:0030521=GO_REF:0000019, GO:0050750=PMID:15082773} P31689 DnaJ homolog subfamily A member 1 protein 20040806 {GO:0006986=TAS, GO:0016020=IEA, GO:0009408=IEA, GO:0006457=IEA, GO:0031072=IEA, GO:0030317=IEA, GO:0007283=IEA, GO:0051082=IEA, GO:0005524=IEA, GO:0046872=IEA, GO:0030521=IEA, GO:0050750=IDA} androgen receptor signaling pathway, protein folding, response to heat, response to unfolded protein, sperm motility, spermatogenesis membrane ATP binding, heat shock protein binding, low-density lipoprotein particle receptor binding, metal ion binding, unfolded protein binding Human DNAJA2 PINC UniProtKB {GO:0008284=PMID:9383053, GO:0016020=GO_REF:0000039, GO:0009408=GO_REF:0000002, GO:0006457=GO_REF:0000002, GO:0031072=GO_REF:0000002, GO:0051082=GO_REF:0000002, GO:0005524=GO_REF:0000002, GO:0046872=GO_REF:0000037} O60884 DnaJ homolog subfamily A member 2 protein 20030904 {GO:0008284=TAS, GO:0016020=IEA, GO:0009408=IEA, GO:0006457=IEA, GO:0031072=IEA, GO:0051082=IEA, GO:0005524=IEA, GO:0046872=IEA} positive regulation of cell proliferation, protein folding, response to heat membrane ATP binding, heat shock protein binding, metal ion binding, unfolded protein binding Human DNAJA3 IntAct UniProtKB {GO:0005515=PMID:21106534, GO:0030054=GO_REF:0000037, GO:0008285=PMID:11719219, GO:0031594=GO_REF:0000024, GO:0009408=GO_REF:0000002, GO:0007264=GO_REF:0000019, GO:0005884=PMID:17588722, GO:0005634=GO_REF:0000019, GO:0009790=GO_REF:0000019, GO:0006924=GO_REF:0000019, GO:0046872=GO_REF:0000037, GO:0005829=GO_REF:0000039, GO:0005083=GO_REF:0000019, GO:0006457=GO_REF:0000002, GO:0045211=GO_REF:0000024, GO:0031072=GO_REF:0000002, GO:0005759=PMID:11719219, GO:0042102=GO_REF:0000019, GO:0030971=GO_REF:0000019, GO:0033077=GO_REF:0000019, GO:0007569=GO_REF:0000019, GO:0000122=PMID:21106534, GO:0005524=GO_REF:0000002, GO:0051082=GO_REF:0000019, GO:0006264=GO_REF:0000019, GO:0071340=GO_REF:0000024, GO:0019897=GO_REF:0000024} Q96EY1 DnaJ homolog subfamily A member 3, mitochondrial protein 20130415 {GO:0005515=IPI, GO:0030054=IEA, GO:0008285=IDA, GO:0031594=ISS, GO:0009408=IEA, GO:0007264=IEA, GO:0005884=IDA, GO:0005634=IEA, GO:0009790=IEA, GO:0006924=IEA, GO:0046872=IEA, GO:0005829=IEA, GO:0005083=IEA, GO:0006457=IEA, GO:0045211=ISS, GO:0031072=IEA, GO:0005759=IDA, GO:0042102=IEA, GO:0030971=IEA, GO:0033077=IEA, GO:0007569=IEA, GO:0000122=IDA, GO:0005524=IEA, GO:0051082=IEA, GO:0006264=IEA, GO:0071340=ISS, GO:0019897=ISS} T cell differentiation in thymus, activation-induced cell death of T cells, cell aging, embryo development, mitochondrial DNA replication, negative regulation of cell proliferation, negative regulation of transcription from RNA polymerase II promoter, positive regulation of T cell proliferation, protein folding, response to heat, skeletal muscle acetylcholine-gated channel clustering, small GTPase mediated signal transduction actin filament, cell junction, cytosol, extrinsic to plasma membrane, mitochondrial matrix, neuromuscular junction, nucleus, postsynaptic membrane ATP binding, heat shock protein binding, metal ion binding, protein binding, receptor tyrosine kinase binding, small GTPase regulator activity, unfolded protein binding Human UniProtKB:P51692 DNAJA4 UniProtKB UniProtKB {GO:0016020=GO_REF:0000039, GO:0009408=GO_REF:0000002, GO:0006457=GO_REF:0000002, GO:0031072=GO_REF:0000002, GO:0051082=GO_REF:0000002, GO:0005524=GO_REF:0000002, GO:0046872=GO_REF:0000037} Q8WW22 DnaJ homolog subfamily A member 4 protein 20130413 {GO:0016020=IEA, GO:0009408=IEA, GO:0006457=IEA, GO:0031072=IEA, GO:0051082=IEA, GO:0005524=IEA, GO:0046872=IEA} protein folding, response to heat membrane ATP binding, heat shock protein binding, metal ion binding, unfolded protein binding Human UniProtKB-SubCell:SL-0162 DNAJB1 PINC UniProtKB {GO:0006986=PMID:8975727, GO:0005737=GO_REF:0000039, GO:0070389=PMID:18620420, GO:0006457=GO_REF:0000002, GO:0005730=GO_REF:0000039, GO:0051085=GO_REF:0000019, GO:0051082=GO_REF:0000002} P25685 DnaJ homolog subfamily B member 1 protein 20040806 {GO:0006986=TAS, GO:0005737=IEA, GO:0070389=IDA, GO:0006457=IEA, GO:0005730=IEA, GO:0051085=IEA, GO:0051082=IEA} chaperone cofactor-dependent protein refolding, chaperone mediated protein folding requiring cofactor, protein folding, response to unfolded protein cytoplasm, nucleolus unfolded protein binding Human DNAJB11 Reactome UniProtKB {GO:0005783=PMID:16130169, GO:0016556=GO_REF:0000019, GO:0006457=GO_REF:0000002, GO:0005788=Reactome:REACT_116120, GO:0005634=GO_REF:0000019, GO:0051082=GO_REF:0000019, GO:0006987=Reactome:REACT_18368, GO:0044267=Reactome:REACT_17015, GO:0030968=Reactome:REACT_18356} Q9UBS4 DnaJ homolog subfamily B member 11 protein 20130301 {GO:0005783=TAS, GO:0016556=IEA, GO:0006457=IEA, GO:0005788=TAS, GO:0005634=IEA, GO:0051082=IEA, GO:0006987=TAS, GO:0044267=TAS, GO:0030968=TAS} activation of signaling protein activity involved in unfolded protein response, cellular protein metabolic process, endoplasmic reticulum unfolded protein response, mRNA modification, protein folding endoplasmic reticulum, endoplasmic reticulum lumen, nucleus unfolded protein binding Human DNAJB12 UniProtKB UniProtKB {GO:0016021=GO_REF:0000037} Q9NXW2 DnaJ homolog subfamily B member 12 protein 20130413 {GO:0016021=IEA} integral to membrane Human UniProtKB-KW:KW-0812 DNAJB14 UniProtKB UniProtKB {GO:0016021=GO_REF:0000037} Q8TBM8 DnaJ homolog subfamily B member 14 protein 20130413 {GO:0016021=IEA} integral to membrane Human UniProtKB-KW:KW-0812 DNAJB2 PINC UniProtKB {GO:0006986=PMID:1599432, GO:0008219=GO_REF:0000037, GO:0030308=PMID:9553041, GO:0008285=PMID:9553041, GO:0006457=PMID:1599432, GO:0051082=PMID:1599432} P25686 DnaJ homolog subfamily B member 2 protein 20030904 {GO:0006986=TAS, GO:0008219=IEA, GO:0030308=IGI, GO:0008285=IGI, GO:0006457=TAS, GO:0051082=TAS} cell death, negative regulation of cell growth, negative regulation of cell proliferation, protein folding, response to unfolded protein unfolded protein binding Human DNAJB4 HPA UniProtKB {GO:0006986=PMID:9546042, GO:0005515=PMID:21255413, GO:0005737=GO_REF:0000052, GO:0009408=PMID:9546042, GO:0005886=GO_REF:0000052, GO:0006457=GO_REF:0000002, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0051082=GO_REF:0000002} Q9UDY4 DnaJ homolog subfamily B member 4 protein 20111111 {GO:0006986=TAS, GO:0005515=IPI, GO:0005737=IDA, GO:0009408=TAS, GO:0005886=IDA, GO:0006457=IEA, GO:0005730=IDA, GO:0005634=IDA, GO:0051082=IEA} protein folding, response to heat, response to unfolded protein cytoplasm, nucleolus, nucleus, plasma membrane protein binding, unfolded protein binding Human DNAJB5 ENSEMBL UniProtKB {GO:0005515=PMID:21078624, GO:0006986=PMID:10570961, GO:0006457=GO_REF:0000002, GO:0005634=GO_REF:0000019, GO:0000122=GO_REF:0000019, GO:0051082=GO_REF:0000002, GO:0005829=GO_REF:0000019} Q5T657 DnaJ homolog subfamily B member 5 protein 20130413 {GO:0005515=IPI, GO:0006986=IEP, GO:0006457=IEA, GO:0005634=IEA, GO:0000122=IEA, GO:0051082=IEA, GO:0005829=IEA} negative regulation of transcription from RNA polymerase II promoter, protein folding, response to unfolded protein cytosol, nucleus protein binding, unfolded protein binding Human Ensembl:ENSMUSP00000081712 DNAJB6 GOC UniProtKB {GO:0005515=PMID:16919237, GO:0006986=GO_REF:0000029, GO:0030018=PMID:22366786, GO:0048471=PMID:10954706, GO:0045109=PMID:10954706, GO:0005730=GO_REF:0000052, GO:0051087=PMID:11896048, GO:0005634=GO_REF:0000052, GO:0032781=PMID:11896048, GO:0005737=GO_REF:0000052, GO:0006457=PMID:11896048, GO:0031072=PMID:10954706, GO:0043154=PMID:11896048, GO:0001671=PMID:11896048} O75190 DnaJ homolog subfamily B member 6 protein 20130413 {GO:0005515=IPI, GO:0006986=NAS, GO:0030018=IDA, GO:0048471=IDA, GO:0045109=IDA, GO:0005730=IDA, GO:0051087=IDA, GO:0005634=IDA, GO:0032781=IDA, GO:0005737=IDA, GO:0006457=IDA, GO:0031072=IDA, GO:0043154=IDA, GO:0001671=IDA} intermediate filament organization, negative regulation of cysteine-type endopeptidase activity involved in apoptotic process, positive regulation of ATPase activity, protein folding, response to unfolded protein Z disc, cytoplasm, nucleolus, nucleus, perinuclear region of cytoplasm ATPase activator activity, chaperone binding, heat shock protein binding, protein binding Human DNAJB8 null null {} null null null null {} null null null DNAJB9 Reactome UniProtKB {GO:0051787=PMID:18400946, GO:0005515=PMID:19815549, GO:0005737=GO_REF:0000024, GO:0005783=GO_REF:0000054, GO:0005789=Reactome:REACT_115866, GO:0005730=GO_REF:0000024, GO:0006987=Reactome:REACT_18368, GO:0030433=PMID:18400946, GO:0044267=Reactome:REACT_17015, GO:0030968=Reactome:REACT_18356} Q9UBS3 DnaJ homolog subfamily B member 9 protein 20130301 {GO:0051787=IDA, GO:0005515=IPI, GO:0005737=ISS, GO:0005783=IDA, GO:0005789=TAS, GO:0005730=ISS, GO:0006987=TAS, GO:0030433=IMP, GO:0044267=TAS, GO:0030968=TAS} ER-associated protein catabolic process, activation of signaling protein activity involved in unfolded protein response, cellular protein metabolic process, endoplasmic reticulum unfolded protein response cytoplasm, endoplasmic reticulum, endoplasmic reticulum membrane, nucleolus misfolded protein binding, protein binding Human DNAJC1 HPA UniProtKB {GO:0005515=PMID:14668352, GO:0031965=GO_REF:0000039, GO:0005783=GO_REF:0000052, GO:0051087=GO_REF:0000019, GO:0032781=PMID:14668352, GO:0003677=GO_REF:0000037, GO:0006417=GO_REF:0000019, GO:0045861=PMID:14668352, GO:0006457=GO_REF:0000019, GO:0003682=GO_REF:0000002, GO:0005789=GO_REF:0000039, GO:0050708=PMID:14668352, GO:0016021=GO_REF:0000037, GO:0001671=PMID:14668352} Q96KC8 DnaJ homolog subfamily C member 1 protein 20081203 {GO:0005515=IPI, GO:0031965=IEA, GO:0005783=IDA, GO:0051087=IEA, GO:0032781=TAS, GO:0003677=IEA, GO:0006417=IEA, GO:0045861=TAS, GO:0006457=IEA, GO:0003682=IEA, GO:0005789=IEA, GO:0050708=IDA, GO:0016021=IEA, GO:0001671=TAS} negative regulation of proteolysis, positive regulation of ATPase activity, protein folding, regulation of protein secretion, regulation of translation endoplasmic reticulum, endoplasmic reticulum membrane, integral to membrane, nuclear membrane ATPase activator activity, DNA binding, chaperone binding, chromatin binding, protein binding Human DNAJC10 UniProtKB UniProtKB {GO:0005515=PMID:19815549, GO:0034976=PMID:19122239, GO:0005783=PMID:12411443, GO:0006662=GO_REF:0000002, GO:0051087=PMID:12411443, GO:0015035=GO_REF:0000002, GO:0015036=GO_REF:0000024, GO:0009055=GO_REF:0000002, GO:0005576=GO_REF:0000039, GO:0032781=GO_REF:0000024, GO:0030433=PMID:18400946, GO:0051787=PMID:18400946, GO:0070059=PMID:19122239, GO:0034663=PMID:18400946, GO:0005788=GO_REF:0000039, GO:0001933=PMID:19122239, GO:0051117=PMID:12411443, GO:0045454=GO_REF:0000002, GO:0001671=GO_REF:0000024} Q8IXB1 DnaJ homolog subfamily C member 10 protein 20100203 {GO:0005515=IPI, GO:0034976=IDA, GO:0005783=IDA, GO:0006662=IEA, GO:0051087=IDA, GO:0015035=IEA, GO:0015036=ISS, GO:0009055=IEA, GO:0005576=IEA, GO:0032781=ISS, GO:0030433=IMP, GO:0051787=IDA, GO:0070059=IDA, GO:0034663=IDA, GO:0005788=IEA, GO:0001933=IDA, GO:0051117=IPI, GO:0045454=IEA, GO:0001671=ISS} ER-associated protein catabolic process, cell redox homeostasis, glycerol ether metabolic process, intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress, negative regulation of protein phosphorylation, positive regulation of ATPase activity, response to endoplasmic reticulum stress endoplasmic reticulum, endoplasmic reticulum chaperone complex, endoplasmic reticulum lumen, extracellular region ATPase activator activity, ATPase binding, chaperone binding, disulfide oxidoreductase activity, electron carrier activity, misfolded protein binding, protein binding, protein disulfide oxidoreductase activity Human UniProtKB:Q5HYA8 DNAJC11 ENSEMBL UniProtKB {GO:0005743=GO_REF:0000019} Q9NVH1 DnaJ homolog subfamily C member 11 protein 20130413 {GO:0005743=IEA} mitochondrial inner membrane Human Ensembl:ENSMUSP00000051643 DNAJC12 null null {} null null null null {} null null null DNAJC13 null null {} null null null null {} null null null DNAJC14 HPA UniProtKB {GO:0005730=GO_REF:0000052, GO:0005789=GO_REF:0000039, GO:0005634=GO_REF:0000052, GO:0016021=GO_REF:0000037, GO:0015031=GO_REF:0000037} Q6Y2X3 DnaJ homolog subfamily C member 14 protein 20120912 {GO:0005730=IDA, GO:0005789=IEA, GO:0005634=IDA, GO:0016021=IEA, GO:0015031=IEA} protein transport endoplasmic reticulum membrane, integral to membrane, nucleolus, nucleus NOT Human DNAJC15 ENSEMBL UniProtKB {GO:0005739=GO_REF:0000019, GO:0016021=GO_REF:0000037} Q9Y5T4 DnaJ homolog subfamily C member 15 protein 20130413 {GO:0005739=IEA, GO:0016021=IEA} integral to membrane, mitochondrion Human Ensembl:ENSMUSP00000022590 DNAJC16 UniProtKB UniProtKB {GO:0045454=GO_REF:0000002, GO:0016021=GO_REF:0000037} Q9Y2G8 DnaJ homolog subfamily C member 16 protein 20130413 {GO:0045454=IEA, GO:0016021=IEA} cell redox homeostasis integral to membrane Human UniProtKB-KW:KW-0812 DNAJC17 UniProtKB UniProtKB {GO:0000166=GO_REF:0000002, GO:0003723=GO_REF:0000037} Q9NVM6 DnaJ homolog subfamily C member 17 protein 20130413 {GO:0000166=IEA, GO:0003723=IEA} RNA binding, nucleotide binding Human UniProtKB-KW:KW-0694 DNAJC19 Reactome UniProtKB {GO:0005739=PMID:12592411, GO:0006457=PMID:16055927, GO:0006626=Reactome:REACT_118595, GO:0005743=GO_REF:0000039, GO:0048806=PMID:16055927, GO:0016021=PMID:16055927, GO:0044267=Reactome:REACT_17015, GO:0007601=PMID:16055927} Q96DA6 Mitochondrial import inner membrane translocase subunit TIM14 protein 20110427 {GO:0005739=IDA, GO:0006457=NAS, GO:0006626=TAS, GO:0005743=IEA, GO:0048806=IMP, GO:0016021=NAS, GO:0044267=TAS, GO:0007601=IMP} cellular protein metabolic process, genitalia development, protein folding, protein targeting to mitochondrion, visual perception integral to membrane, mitochondrial inner membrane, mitochondrion Human DNAJC2 HPA UniProtKB {GO:0043130=PMID:21179169, GO:0031965=GO_REF:0000052, GO:0030308=GO_REF:0000019, GO:0005634=PMID:21179169, GO:0003677=GO_REF:0000002, GO:0006351=GO_REF:0000037, GO:0005829=PMID:16002468, GO:0006260=GO_REF:0000019, GO:0000085=GO_REF:0000019, GO:0042393=PMID:21179169, GO:0005737=GO_REF:0000052, GO:0003682=PMID:21179169, GO:0030544=PMID:16002468, GO:0051083=PMID:16002468, GO:0045893=PMID:21179169, GO:0016568=GO_REF:0000037} Q99543 DnaJ homolog subfamily C member 2 protein 20100326 {GO:0043130=IDA, GO:0031965=IDA, GO:0030308=IEA, GO:0005634=IDA, GO:0003677=IEA, GO:0006351=IEA, GO:0005829=IDA, GO:0006260=IEA, GO:0000085=IEA, GO:0042393=IDA, GO:0005737=IDA, GO:0003682=IDA, GO:0030544=IPI, GO:0051083=TAS, GO:0045893=IDA, GO:0016568=IEA} 'de novo' cotranslational protein folding, DNA replication, G2 phase of mitotic cell cycle, chromatin modification, negative regulation of cell growth, positive regulation of transcription, DNA-dependent, transcription, DNA-dependent cytoplasm, cytosol, nuclear membrane, nucleus DNA binding, Hsp70 protein binding, chromatin binding, histone binding, ubiquitin binding Human DNAJC21 IntAct UniProtKB {GO:0005515=PMID:20195357, GO:0003674=GO_REF:0000015, GO:0006457=PMID:16952052, GO:0005840=PMID:16952052, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002} Q5F1R6 DnaJ homolog subfamily C member 21 protein 20130415 {GO:0005515=IPI, GO:0003674=ND, GO:0006457=NAS, GO:0005840=NAS, GO:0008270=IEA, GO:0003676=IEA} protein folding ribosome molecular_function, nucleic acid binding, protein binding, zinc ion binding Human UniProtKB:Q99551 DNAJC22 UniProtKB UniProtKB {GO:0016021=GO_REF:0000037} Q8N4W6 DnaJ homolog subfamily C member 22 protein 20130413 {GO:0016021=IEA} integral to membrane Human UniProtKB-KW:KW-0812 DNAJC28 null null {} null null null null {} null null null DNAJC3 GOC UniProtKB {GO:0051787=GO_REF:0000019, GO:0005737=PMID:8666242, GO:0051607=GO_REF:0000037, GO:0051603=GO_REF:0000019, GO:0051087=GO_REF:0000019, GO:0005788=Reactome:REACT_115787, GO:0004860=PMID:7511204, GO:0006469=PMID:7511204, GO:0006987=Reactome:REACT_18368, GO:0044267=Reactome:REACT_17015, GO:0031205=GO_REF:0000019, GO:0030968=Reactome:REACT_18356} Q13217 DnaJ homolog subfamily C member 3 protein 20130413 {GO:0051787=IEA, GO:0005737=TAS, GO:0051607=IEA, GO:0051603=IEA, GO:0051087=IEA, GO:0005788=TAS, GO:0004860=TAS, GO:0006469=TAS, GO:0006987=TAS, GO:0044267=TAS, GO:0031205=IEA, GO:0030968=TAS} activation of signaling protein activity involved in unfolded protein response, cellular protein metabolic process, defense response to virus, endoplasmic reticulum unfolded protein response, negative regulation of protein kinase activity, proteolysis involved in cellular protein catabolic process cytoplasm, endoplasmic reticulum Sec complex, endoplasmic reticulum lumen chaperone binding, misfolded protein binding, protein kinase inhibitor activity Human DNAJC30 ENSEMBL UniProtKB {GO:0005739=GO_REF:0000019} Q96LL9 DnaJ homolog subfamily C member 30 protein 20130413 {GO:0005739=IEA} mitochondrion Human Ensembl:ENSMUSP00000094318 DNAJC4 PINC UniProtKB {GO:0006986=PMID:9473517, GO:0005739=GO_REF:0000019, GO:0016020=PMID:9473517, GO:0006457=PMID:9473517, GO:0051082=PMID:9473517, GO:0016021=GO_REF:0000037} Q9NNZ3 DnaJ homolog subfamily C member 4 protein 20050308 {GO:0006986=TAS, GO:0005739=IEA, GO:0016020=NAS, GO:0006457=NAS, GO:0051082=NAS, GO:0016021=IEA} protein folding, response to unfolded protein integral to membrane, membrane, mitochondrion unfolded protein binding Human DNAJC5 Reactome UniProtKB {GO:0042470=GO_REF:0000039, GO:0008219=GO_REF:0000037, GO:0043524=GO_REF:0000019, GO:0043008=GO_REF:0000019, GO:0001948=GO_REF:0000019, GO:0005886=Reactome:REACT_23813, GO:0007268=Reactome:REACT_13685, GO:0061202=Reactome:REACT_23973, GO:0007269=Reactome:REACT_13723, GO:0008021=GO_REF:0000019} Q9H3Z4 DnaJ homolog subfamily C member 5 protein 20120214 {GO:0042470=IEA, GO:0008219=IEA, GO:0043524=IEA, GO:0043008=IEA, GO:0001948=IEA, GO:0005886=TAS, GO:0007268=TAS, GO:0061202=TAS, GO:0007269=TAS, GO:0008021=IEA} cell death, negative regulation of neuron apoptotic process, neurotransmitter secretion, synaptic transmission clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane, melanosome, plasma membrane, synaptic vesicle ATP-dependent protein binding, glycoprotein binding Human DNAJC5B UniProtKB UniProtKB {GO:0016020=GO_REF:0000039} Q9UF47 DnaJ homolog subfamily C member 5B protein 20130413 {GO:0016020=IEA} membrane Human UniProtKB-SubCell:SL-0162 DNAJC6 Reactome UniProtKB {GO:0017124=GO_REF:0000037, GO:0006892=Reactome:REACT_11235, GO:0016044=Reactome:REACT_11123, GO:0004725=GO_REF:0000003, GO:0005829=Reactome:REACT_19206} O75061 Putative tyrosine-protein phosphatase auxilin protein 20130213 {GO:0017124=IEA, GO:0006892=TAS, GO:0016044=TAS, GO:0004725=IEA, GO:0005829=TAS} cellular membrane organization, post-Golgi vesicle-mediated transport cytosol SH3 domain binding, protein tyrosine phosphatase activity Human DNAJC7 HPA UniProtKB {GO:0005515=PMID:22190034, GO:0005737=GO_REF:0000052, GO:0006457=PMID:8836031, GO:0070389=PMID:18620420, GO:0031072=PMID:12853476, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0005856=GO_REF:0000039} Q99615 DnaJ homolog subfamily C member 7 protein 20100326 {GO:0005515=IPI, GO:0005737=IDA, GO:0006457=TAS, GO:0070389=IDA, GO:0031072=IPI, GO:0005730=IDA, GO:0005634=IDA, GO:0005856=IEA} chaperone cofactor-dependent protein refolding, protein folding cytoplasm, cytoskeleton, nucleolus, nucleus heat shock protein binding, protein binding Human DNAJC8 Reactome UniProtKB {GO:0008380=Reactome:REACT_1735, GO:0010467=Reactome:REACT_71, GO:0000398=Reactome:REACT_467, GO:0005654=Reactome:REACT_1935} O75937 DnaJ homolog subfamily C member 8 protein 20130213 {GO:0008380=TAS, GO:0010467=TAS, GO:0000398=TAS, GO:0005654=TAS} RNA splicing, gene expression, mRNA splicing, via spliceosome nucleoplasm Human DNAJC9 UniProtKB UniProtKB {GO:0035176=PMID:21531385} Q8WXX5 DnaJ homolog subfamily C member 9 protein 20111216 {GO:0035176=IEP} social behavior Human DNAL4 Reactome UniProtKB {GO:0048011=Reactome:REACT_11061, GO:0005886=Reactome:REACT_12385, GO:0042623=GO_REF:0000029, GO:0005875=GO_REF:0000002, GO:0005874=GO_REF:0000037, GO:0005858=GO_REF:0000029, GO:0003777=GO_REF:0000029, GO:0035085=GO_REF:0000039, GO:0007017=GO_REF:0000002, GO:0007018=GO_REF:0000029} O96015 Dynein light chain 4, axonemal protein 20130301 {GO:0048011=TAS, GO:0005886=TAS, GO:0042623=NAS, GO:0005875=IEA, GO:0005874=IEA, GO:0005858=NAS, GO:0003777=NAS, GO:0035085=IEA, GO:0007017=IEA, GO:0007018=NAS} microtubule-based movement, microtubule-based process, neurotrophin TRK receptor signaling pathway axonemal dynein complex, cilium axoneme, microtubule, microtubule associated complex, plasma membrane ATPase activity, coupled, microtubule motor activity Human DNALI1 BHF-UCL UniProtKB {GO:0007338=PMID:9284741, GO:0005737=PMID:19944400, GO:0005930=PMID:9284741, GO:0006928=PMID:9284741, GO:0005858=PMID:9284741, GO:0003777=PMID:9284741} O14645 Axonemal dynein light intermediate polypeptide 1 protein 20120423 {GO:0007338=TAS, GO:0005737=IDA, GO:0005930=TAS, GO:0006928=TAS, GO:0005858=TAS, GO:0003777=TAS} cellular component movement, single fertilization axonemal dynein complex, axoneme, cytoplasm microtubule motor activity Human DNASE1 UniProtKB UniProtKB {GO:0005515=PMID:12849983, GO:0004536=GO_REF:0000002, GO:0006308=GO_REF:0000002, GO:0006915=GO_REF:0000037, GO:0005576=GO_REF:0000039, GO:0003779=GO_REF:0000037, GO:0005635=GO_REF:0000039, GO:0004530=GO_REF:0000003, GO:0016888=GO_REF:0000002} P24855 Deoxyribonuclease-1 protein 20051104 {GO:0005515=IPI, GO:0004536=IEA, GO:0006308=IEA, GO:0006915=IEA, GO:0005576=IEA, GO:0003779=IEA, GO:0005635=IEA, GO:0004530=IEA, GO:0016888=IEA} DNA catabolic process, apoptotic process extracellular region, nuclear envelope actin binding, deoxyribonuclease I activity, deoxyribonuclease activity, endodeoxyribonuclease activity, producing 5'-phosphomonoesters, protein binding Human UniProtKB:P68133 DNASE1L2 PINC UniProtKB {GO:0004536=PMID:9205125, GO:0006308=GO_REF:0000002, GO:0005509=PMID:9205125, GO:0005576=GO_REF:0000039, GO:0006259=PMID:9205125, GO:0016888=GO_REF:0000002, GO:0003677=PMID:9205125} Q92874 Deoxyribonuclease-1-like 2 protein 20030904 {GO:0004536=TAS, GO:0006308=IEA, GO:0005509=TAS, GO:0005576=IEA, GO:0006259=TAS, GO:0016888=IEA, GO:0003677=TAS} DNA catabolic process, DNA metabolic process extracellular region DNA binding, calcium ion binding, deoxyribonuclease activity, endodeoxyribonuclease activity, producing 5'-phosphomonoesters Human DNASE2 PINC UniProtKB {GO:0006308=GO_REF:0000019, GO:0030218=GO_REF:0000019, GO:0006915=GO_REF:0000037, GO:0004531=GO_REF:0000003, GO:0006259=PMID:9714827, GO:0003677=PMID:9714827, GO:0005764=GO_REF:0000039} O00115 Deoxyribonuclease-2-alpha protein 20030904 {GO:0006308=IEA, GO:0030218=IEA, GO:0006915=IEA, GO:0004531=IEA, GO:0006259=TAS, GO:0003677=TAS, GO:0005764=IEA} DNA catabolic process, DNA metabolic process, apoptotic process, erythrocyte differentiation lysosome DNA binding, deoxyribonuclease II activity Human DNASE2B UniProtKB UniProtKB {GO:0005576=GO_REF:0000019, GO:0004531=GO_REF:0000003, GO:0006259=GO_REF:0000002, GO:0005764=GO_REF:0000039} Q8WZ79 Deoxyribonuclease-2-beta protein 20130413 {GO:0005576=IEA, GO:0004531=IEA, GO:0006259=IEA, GO:0005764=IEA} DNA metabolic process extracellular region, lysosome deoxyribonuclease II activity Human UniProtKB-SubCell:SL-0158 DNER Reactome UniProtKB {GO:0005515=PMID:11950833, GO:0007220=GO_REF:0000019, GO:0005886=PMID:11950833, GO:0005509=PMID:11950833, GO:0005112=GO_REF:0000019, GO:0048741=GO_REF:0000019, GO:0007417=PMID:11950833, GO:0007416=PMID:11950833, GO:0030425=PMID:11950833, GO:0006897=PMID:11950833, GO:0007219=Reactome:REACT_118859, GO:0030276=PMID:11950833, GO:0043025=GO_REF:0000019, GO:0010001=GO_REF:0000019, GO:0016021=GO_REF:0000037, GO:0001764=PMID:11950833, GO:0005769=PMID:11950833, GO:0004888=PMID:11950833} Q8NFT8 Delta and Notch-like epidermal growth factor-related receptor protein 20110917 {GO:0005515=IPI, GO:0007220=IEA, GO:0005886=IDA, GO:0005509=NAS, GO:0005112=IEA, GO:0048741=IEA, GO:0007417=IEP, GO:0007416=NAS, GO:0030425=IDA, GO:0006897=NAS, GO:0007219=TAS, GO:0030276=TAS, GO:0043025=IEA, GO:0010001=IEA, GO:0016021=IEA, GO:0001764=NAS, GO:0005769=IDA, GO:0004888=TAS} Notch receptor processing, Notch signaling pathway, central nervous system development, endocytosis, glial cell differentiation, neuron migration, skeletal muscle fiber development, synapse assembly dendrite, early endosome, integral to membrane, neuronal cell body, plasma membrane Notch binding, calcium ion binding, clathrin binding, protein binding, transmembrane signaling receptor activity Human DNHD1 InterPro UniProtKB {GO:0030286=GO_REF:0000002, GO:0003777=GO_REF:0000002, GO:0007018=GO_REF:0000002} Q96M86 Dynein heavy chain domain-containing protein 1 protein 20130413 {GO:0030286=IEA, GO:0003777=IEA, GO:0007018=IEA} microtubule-based movement dynein complex microtubule motor activity Human InterPro:IPR004273 DNLZ ENSEMBL UniProtKB {GO:0005739=GO_REF:0000019, GO:0008270=GO_REF:0000002} Q5SXM8 DNL-type zinc finger protein protein 20130413 {GO:0005739=IEA, GO:0008270=IEA} mitochondrion zinc ion binding Human Ensembl:ENSMUSP00000028295 DNM1 GOC UniProtKB {GO:0005515=PMID:21706016, GO:0005874=GO_REF:0000037, GO:0003924=GO_REF:0000002, GO:0005525=GO_REF:0000037, GO:0008022=GO_REF:0000019, GO:0032403=GO_REF:0000019, GO:0030117=GO_REF:0000019, GO:0006898=PMID:10521508, GO:0042802=PMID:21962517, GO:0006897=PMID:19706678, GO:0006184=PMID:10944110, GO:0031623=GO_REF:0000019, GO:0005543=GO_REF:0000002, GO:0007032=PMID:19706678} Q05193 Dynamin-1 protein 20130413 {GO:0005515=IPI, GO:0005874=IEA, GO:0003924=IEA, GO:0005525=IEA, GO:0008022=IEA, GO:0032403=IEA, GO:0030117=IEA, GO:0006898=IMP, GO:0042802=IPI, GO:0006897=IMP, GO:0006184=TAS, GO:0031623=IEA, GO:0005543=IEA, GO:0007032=IMP} GTP catabolic process, endocytosis, endosome organization, receptor internalization, receptor-mediated endocytosis membrane coat, microtubule GTP binding, GTPase activity, identical protein binding, phospholipid binding, protein C-terminus binding, protein binding, protein complex binding Human DNM1L BHF-UCL UniProtKB {GO:0005515=PMID:21217774, GO:0003374=PMID:11514614, GO:0048471=PMID:9570752, GO:0090149=PMID:11514614, GO:1900063=PMID:18353969, GO:0050714=PMID:9570752, GO:0003924=GO_REF:0000002, GO:0005741=Reactome:REACT_13560, GO:0090141=PMID:20436456, GO:0006921=Reactome:REACT_995, GO:0005829=Reactome:REACT_13560, GO:0005737=PMID:21149567, GO:0051289=PMID:18353969, GO:0090200=PMID:21149567, GO:0031625=PMID:19407830, GO:0016559=PMID:12618434, GO:0005777=PMID:12618434, GO:0005794=PMID:20688057, GO:0010821=PMID:21149567, GO:0006915=Reactome:REACT_578, GO:2001244=PMID:20850011, GO:0005525=GO_REF:0000037, GO:0043653=PMID:12499352, GO:0012505=GO_REF:0000039, GO:0043234=PMID:17408615, GO:0070584=PMID:21149567} O00429 Dynamin-1-like protein protein 20110404 {GO:0005515=IPI, GO:0003374=IDA, GO:0048471=IDA, GO:0090149=IDA, GO:1900063=IMP, GO:0050714=IDA, GO:0003924=IEA, GO:0005741=TAS, GO:0090141=TAS, GO:0006921=TAS, GO:0005829=TAS, GO:0005737=IDA, GO:0051289=IDA, GO:0090200=IMP, GO:0031625=IPI, GO:0016559=IDA, GO:0005777=IDA, GO:0005794=IDA, GO:0010821=IMP, GO:0006915=TAS, GO:2001244=IMP, GO:0005525=IEA, GO:0043653=IMP, GO:0012505=IEA, GO:0043234=IDA, GO:0070584=IMP} apoptotic process, cellular component disassembly involved in execution phase of apoptosis, dynamin polymerization involved in mitochondrial fission, membrane fission involved in mitochondrial fission, mitochondrial fragmentation involved in apoptotic process, mitochondrion morphogenesis, peroxisome fission, positive regulation of intrinsic apoptotic signaling pathway, positive regulation of mitochondrial fission, positive regulation of protein secretion, positive regulation of release of cytochrome c from mitochondria, protein homotetramerization, regulation of mitochondrion organization, regulation of peroxisome organization Golgi apparatus, cytoplasm, cytosol, endomembrane system, mitochondrial outer membrane, perinuclear region of cytoplasm, peroxisome, protein complex GTP binding, GTPase activity, protein binding, ubiquitin protein ligase binding Human DNM2 GOC UniProtKB {GO:0005515=PMID:22623184, GO:0008017=PMID:7590285, GO:0030054=GO_REF:0000037, GO:0005886=Reactome:REACT_12634, GO:0050999=Reactome:REACT_12541, GO:0003924=Reactome:REACT_19255, GO:0005634=GO_REF:0000019, GO:0044281=Reactome:REACT_111217, GO:0032403=GO_REF:0000019, GO:0005829=Reactome:REACT_121003, GO:0031623=PMID:14985334, GO:0033572=PMID:14985334, GO:0019886=Reactome:REACT_121399, GO:0005737=GO_REF:0000029, GO:0005543=GO_REF:0000002, GO:0045211=PMID:11583995, GO:0000086=PMID:7590285, GO:0046209=Reactome:REACT_12508, GO:0006355=PMID:10893263, GO:0043065=PMID:10893263, GO:0019901=GO_REF:0000019, GO:0005874=PMID:21525035, GO:0006892=Reactome:REACT_11235, GO:0030496=GO_REF:0000039, GO:0014069=GO_REF:0000039, GO:0048489=PMID:11583995, GO:0005525=PMID:7590285, GO:0006898=GO_REF:0000019, GO:0006897=PMID:10101292, GO:0006184=Reactome:REACT_19255, GO:0030666=Reactome:REACT_12634, GO:0007165=PMID:10893263, GO:0045334=GO_REF:0000019, GO:0000139=Reactome:REACT_19334, GO:0019899=PMID:11583995, GO:0045893=PMID:10893263, GO:0016044=Reactome:REACT_11123} P50570 Dynamin-2 protein 20130413 {GO:0005515=IPI, GO:0008017=NAS, GO:0030054=IEA, GO:0005886=TAS, GO:0050999=TAS, GO:0003924=TAS, GO:0005634=IEA, GO:0044281=TAS, GO:0032403=IEA, GO:0005829=TAS, GO:0031623=IMP, GO:0033572=IMP, GO:0019886=TAS, GO:0005737=NAS, GO:0005543=IEA, GO:0045211=IDA, GO:0000086=NAS, GO:0046209=TAS, GO:0006355=NAS, GO:0043065=NAS, GO:0019901=IEA, GO:0005874=IDA, GO:0006892=TAS, GO:0030496=IEA, GO:0014069=IEA, GO:0048489=NAS, GO:0005525=NAS, GO:0006898=IEA, GO:0006897=NAS, GO:0006184=TAS, GO:0030666=TAS, GO:0007165=NAS, GO:0045334=IEA, GO:0000139=TAS, GO:0019899=NAS, GO:0045893=NAS, GO:0016044=TAS} G2/M transition of mitotic cell cycle, GTP catabolic process, antigen processing and presentation of exogenous peptide antigen via MHC class II, cellular membrane organization, endocytosis, nitric oxide metabolic process, positive regulation of apoptotic process, positive regulation of transcription, DNA-dependent, post-Golgi vesicle-mediated transport, receptor internalization, receptor-mediated endocytosis, regulation of nitric-oxide synthase activity, regulation of transcription, DNA-dependent, signal transduction, small molecule metabolic process, synaptic vesicle transport, transferrin transport Golgi membrane, cell junction, clathrin-coated endocytic vesicle, cytoplasm, cytosol, endocytic vesicle membrane, microtubule, midbody, nucleus, plasma membrane, postsynaptic density, postsynaptic membrane GTP binding, GTPase activity, enzyme binding, microtubule binding, phospholipid binding, protein binding, protein complex binding, protein kinase binding Human DNM3 GOC UniProtKB {GO:0005515=PMID:15252009, GO:0048471=GO_REF:0000024, GO:0005874=GO_REF:0000037, GO:0003924=GO_REF:0000024, GO:0014069=GO_REF:0000024, GO:0005525=GO_REF:0000037, GO:0007416=GO_REF:0000024, GO:0006897=GO_REF:0000024, GO:0005739=GO_REF:0000019, GO:0006184=GO_REF:0000024, GO:0005543=GO_REF:0000002, GO:0043197=GO_REF:0000024, GO:0046847=GO_REF:0000024} Q9UQ16 Dynamin-3 protein 20130413 {GO:0005515=IPI, GO:0048471=ISS, GO:0005874=IEA, GO:0003924=ISS, GO:0014069=ISS, GO:0005525=IEA, GO:0007416=ISS, GO:0006897=ISS, GO:0005739=IEA, GO:0006184=ISS, GO:0005543=IEA, GO:0043197=ISS, GO:0046847=ISS} GTP catabolic process, endocytosis, filopodium assembly, synapse assembly dendritic spine, microtubule, mitochondrion, perinuclear region of cytoplasm, postsynaptic density GTP binding, GTPase activity, phospholipid binding, protein binding Human UniProtKB:Q08877 DNMBP IntAct UniProtKB {GO:0005515=PMID:18654987, GO:0005622=GO_REF:0000002, GO:0035556=GO_REF:0000002, GO:0005737=GO_REF:0000002, GO:0030054=GO_REF:0000037, GO:0005795=GO_REF:0000039, GO:0035023=GO_REF:0000002, GO:0045202=GO_REF:0000039, GO:0005856=GO_REF:0000039, GO:0005089=GO_REF:0000002} Q6XZF7 Dynamin-binding protein protein 20130415 {GO:0005515=IPI, GO:0005622=IEA, GO:0035556=IEA, GO:0005737=IEA, GO:0030054=IEA, GO:0005795=IEA, GO:0035023=IEA, GO:0045202=IEA, GO:0005856=IEA, GO:0005089=IEA} intracellular signal transduction, regulation of Rho protein signal transduction Golgi stack, cell junction, cytoplasm, cytoskeleton, intracellular, synapse Rho guanyl-nucleotide exchange factor activity, protein binding Human UniProtKB:Q9NQY0 DNMT1 IntAct UniProtKB {GO:0005515=PMID:22094255, GO:0008327=GO_REF:0000019, GO:0003886=PMID:21745816, GO:0003723=GO_REF:0000019, GO:0005657=GO_REF:0000019, GO:0008168=GO_REF:0000002, GO:0016458=GO_REF:0000019, GO:0005634=GO_REF:0000039, GO:0000122=PMID:10888872, GO:0003677=PMID:18754681, GO:0006351=GO_REF:0000037, GO:0010628=PMID:18413740, GO:0006306=PMID:10888872, GO:0010216=PMID:21745816, GO:0005721=GO_REF:0000019, GO:0051571=PMID:18413740, GO:0071230=GO_REF:0000019, GO:0009008=PMID:18754681, GO:0051573=PMID:18413740, GO:0042127=GO_REF:0000019, GO:0008270=GO_REF:0000019, GO:0008134=GO_REF:0000002, GO:0016568=GO_REF:0000037} P26358 DNA (cytosine-5)-methyltransferase 1 protein 20130415 {GO:0005515=IPI, GO:0008327=IEA, GO:0003886=IDA, GO:0003723=IEA, GO:0005657=IEA, GO:0008168=IEA, GO:0016458=IEA, GO:0005634=IEA, GO:0000122=TAS, GO:0003677=IDA, GO:0006351=IEA, GO:0010628=IMP, GO:0006306=TAS, GO:0010216=IDA, GO:0005721=IEA, GO:0051571=IMP, GO:0071230=IEA, GO:0009008=IDA, GO:0051573=IMP, GO:0042127=IEA, GO:0008270=IEA, GO:0008134=IEA, GO:0016568=IEA} DNA methylation, cellular response to amino acid stimulus, chromatin modification, gene silencing, maintenance of DNA methylation, negative regulation of histone H3-K9 methylation, negative regulation of transcription from RNA polymerase II promoter, positive regulation of gene expression, positive regulation of histone H3-K4 methylation, regulation of cell proliferation, transcription, DNA-dependent centromeric heterochromatin, nucleus, replication fork DNA (cytosine-5-)-methyltransferase activity, DNA binding, DNA-methyltransferase activity, RNA binding, methyl-CpG binding, methyltransferase activity, protein binding, transcription factor binding, zinc ion binding Human UniProtKB:O75530 DNMT3A HPA UniProtKB {GO:0005515=PMID:16357870, GO:0000791=PMID:12138111, GO:0003886=PMID:12138111, GO:0006346=GO_REF:0000019, GO:0008168=GO_REF:0000002, GO:0010424=GO_REF:0000019, GO:0005634=GO_REF:0000052, GO:0007283=GO_REF:0000019, GO:0046872=GO_REF:0000037, GO:0044027=GO_REF:0000019, GO:0016363=PMID:12138111, GO:0045322=GO_REF:0000019, GO:0005737=PMID:12138111, GO:0071230=GO_REF:0000019, GO:0051718=GO_REF:0000019, GO:0043045=GO_REF:0000019, GO:0043046=GO_REF:0000019, GO:0090116=PMID:12138111, GO:0005730=GO_REF:0000052, GO:0000122=GO_REF:0000019, GO:0003677=PMID:12138111, GO:0006306=PMID:12138111, GO:0005720=GO_REF:0000019, GO:0003682=GO_REF:0000019, GO:0006349=PMID:12138111, GO:0046498=GO_REF:0000019, GO:0000775=GO_REF:0000019, GO:0046499=GO_REF:0000019} Q9Y6K1 DNA (cytosine-5)-methyltransferase 3A protein 20111111 {GO:0005515=IPI, GO:0000791=IDA, GO:0003886=IDA, GO:0006346=IEA, GO:0008168=IEA, GO:0010424=IEA, GO:0005634=IDA, GO:0007283=IEA, GO:0046872=IEA, GO:0044027=IEA, GO:0016363=IDA, GO:0045322=IEA, GO:0005737=IDA, GO:0071230=IEA, GO:0051718=IEA, GO:0043045=IEA, GO:0043046=IEA, GO:0090116=IDA, GO:0005730=IDA, GO:0000122=IEA, GO:0003677=IDA, GO:0006306=IDA, GO:0005720=IEA, GO:0003682=IEA, GO:0006349=TAS, GO:0046498=IEA, GO:0000775=IEA, GO:0046499=IEA} C-5 methylation of cytosine, DNA methylation, DNA methylation involved in embryo development, DNA methylation involved in gamete generation, DNA methylation on cytosine within a CG sequence, S-adenosylhomocysteine metabolic process, S-adenosylmethioninamine metabolic process, cellular response to amino acid stimulus, hypermethylation of CpG island, methylation-dependent chromatin silencing, negative regulation of transcription from RNA polymerase II promoter, regulation of gene expression by genetic imprinting, spermatogenesis chromosome, centromeric region, cytoplasm, euchromatin, nuclear heterochromatin, nuclear matrix, nucleolus, nucleus DNA (cytosine-5-)-methyltransferase activity, DNA (cytosine-5-)-methyltransferase activity, acting on CpG substrates, DNA binding, chromatin binding, metal ion binding, methyltransferase activity, protein binding, unmethylated CpG binding NOT Human DNMT3B HPA UniProtKB {GO:0005515=PMID:11735126, GO:0003886=PMID:16543361, GO:0003714=PMID:17303076, GO:0006346=GO_REF:0000019, GO:0031503=GO_REF:0000019, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0000122=PMID:17303076, GO:0003677=GO_REF:0000037, GO:0046872=GO_REF:0000037, GO:0043231=GO_REF:0000052, GO:0006306=PMID:10555141, GO:0010628=PMID:18413740, GO:0005720=GO_REF:0000019, GO:0071230=GO_REF:0000019, GO:0051571=PMID:18413740, GO:0009008=PMID:11102980, GO:0051573=PMID:18413740, GO:0006349=GO_REF:0000019} Q9UBC3 DNA (cytosine-5)-methyltransferase 3B protein 20101115 {GO:0005515=IPI, GO:0003886=IDA, GO:0003714=IDA, GO:0006346=IEA, GO:0031503=IEA, GO:0005730=IDA, GO:0005634=IDA, GO:0000122=IDA, GO:0003677=IEA, GO:0046872=IEA, GO:0043231=IDA, GO:0006306=NAS, GO:0010628=IMP, GO:0005720=IEA, GO:0071230=IEA, GO:0051571=IMP, GO:0009008=NAS, GO:0051573=IMP, GO:0006349=IEA} DNA methylation, cellular response to amino acid stimulus, methylation-dependent chromatin silencing, negative regulation of histone H3-K9 methylation, negative regulation of transcription from RNA polymerase II promoter, positive regulation of gene expression, positive regulation of histone H3-K4 methylation, protein complex localization, regulation of gene expression by genetic imprinting intracellular membrane-bounded organelle, nuclear heterochromatin, nucleolus, nucleus DNA (cytosine-5-)-methyltransferase activity, DNA binding, DNA-methyltransferase activity, metal ion binding, protein binding, transcription corepressor activity Human DNMT3L GOC UniProtKB {GO:0005515=PMID:12202768, GO:0000794=GO_REF:0000019, GO:0005634=PMID:16780588, GO:0001890=GO_REF:0000019, GO:0007283=PMID:11934864, GO:0043085=PMID:16543361, GO:0001701=GO_REF:0000019, GO:0046872=GO_REF:0000037, GO:0005829=PMID:16780588, GO:0006306=PMID:12202768, GO:0005720=GO_REF:0000019, GO:0006349=PMID:12202768, GO:0060718=GO_REF:0000019, GO:0008047=PMID:16543361, GO:0019899=PMID:12202768, GO:0045892=PMID:12202768} Q9UJW3 DNA (cytosine-5)-methyltransferase 3-like protein 20130413 {GO:0005515=IPI, GO:0000794=IEA, GO:0005634=IDA, GO:0001890=IEA, GO:0007283=NAS, GO:0043085=IDA, GO:0001701=IEA, GO:0046872=IEA, GO:0005829=IDA, GO:0006306=NAS, GO:0005720=IEA, GO:0006349=NAS, GO:0060718=IEA, GO:0008047=IDA, GO:0019899=IPI, GO:0045892=IDA} DNA methylation, chorionic trophoblast cell differentiation, in utero embryonic development, negative regulation of transcription, DNA-dependent, placenta development, positive regulation of catalytic activity, regulation of gene expression by genetic imprinting, spermatogenesis condensed nuclear chromosome, cytosol, nuclear heterochromatin, nucleus enzyme activator activity, enzyme binding, metal ion binding, protein binding Human DNPEP PINC UniProtKB {GO:0005737=GO_REF:0000039, GO:0004177=GO_REF:0000037, GO:0006508=GO_REF:0000037, GO:0008270=GO_REF:0000002, GO:0008237=GO_REF:0000037, GO:0006518=PMID:9632644} Q9ULA0 Aspartyl aminopeptidase protein 20030904 {GO:0005737=IEA, GO:0004177=IEA, GO:0006508=IEA, GO:0008270=IEA, GO:0008237=IEA, GO:0006518=TAS} peptide metabolic process, proteolysis cytoplasm aminopeptidase activity, metallopeptidase activity, zinc ion binding Human DNTT HPA UniProtKB {GO:0005737=GO_REF:0000052, GO:0003887=GO_REF:0000002, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0003912=GO_REF:0000003, GO:0006304=GO_REF:0000037, GO:0003677=GO_REF:0000002, GO:0046872=GO_REF:0000037} P04053 DNA nucleotidylexotransferase protein 20110516 {GO:0005737=IDA, GO:0003887=IEA, GO:0005730=IDA, GO:0005634=IDA, GO:0003912=IEA, GO:0006304=IEA, GO:0003677=IEA, GO:0046872=IEA} DNA modification cytoplasm, nucleolus, nucleus DNA binding, DNA nucleotidylexotransferase activity, DNA-directed DNA polymerase activity, metal ion binding Human DNTTIP1 UniProtKB UniProtKB {GO:0005634=GO_REF:0000039} Q9H147 Deoxynucleotidyltransferase terminal-interacting protein 1 protein 20130413 {GO:0005634=IEA} nucleus Human UniProtKB-SubCell:SL-0191 DNTTIP2 HPA UniProtKB {GO:0006355=GO_REF:0000037, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0006351=GO_REF:0000037} Q5QJE6 Deoxynucleotidyltransferase terminal-interacting protein 2 protein 20111111 {GO:0006355=IEA, GO:0005730=IDA, GO:0005634=IDA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleolus, nucleus Human DOC2A PINC UniProtKB {GO:0005515=PMID:18354201, GO:0005215=GO_REF:0000002, GO:0043005=GO_REF:0000039, GO:0030054=GO_REF:0000037, GO:0007268=PMID:7826360, GO:0005764=GO_REF:0000039, GO:0016079=GO_REF:0000019, GO:0008021=GO_REF:0000002, GO:0007399=PMID:7826360, GO:0005544=GO_REF:0000037, GO:0017158=PMID:18354201, GO:0016020=GO_REF:0000002, GO:0030672=GO_REF:0000039} Q14183 Double C2-like domain-containing protein alpha protein 20030904 {GO:0005515=IPI, GO:0005215=IEA, GO:0043005=IEA, GO:0030054=IEA, GO:0007268=TAS, GO:0005764=IEA, GO:0016079=IEA, GO:0008021=IEA, GO:0007399=TAS, GO:0005544=IEA, GO:0017158=IMP, GO:0016020=IEA, GO:0030672=IEA} nervous system development, regulation of calcium ion-dependent exocytosis, synaptic transmission, synaptic vesicle exocytosis cell junction, lysosome, membrane, neuron projection, synaptic vesicle, synaptic vesicle membrane calcium-dependent phospholipid binding, protein binding, transporter activity Human DOC2B HPA UniProtKB {GO:0019905=GO_REF:0000019, GO:0005215=GO_REF:0000002, GO:0005886=GO_REF:0000024, GO:0048791=GO_REF:0000024, GO:0031340=GO_REF:0000024, GO:0031201=GO_REF:0000024, GO:0008021=GO_REF:0000002, GO:0005544=GO_REF:0000024, GO:0005737=GO_REF:0000024, GO:0008104=GO_REF:0000024, GO:0045956=GO_REF:0000024, GO:0015630=GO_REF:0000052, GO:0032024=GO_REF:0000024} Q14184 Double C2-like domain-containing protein beta protein 20120912 {GO:0019905=IEA, GO:0005215=IEA, GO:0005886=ISS, GO:0048791=ISS, GO:0031340=ISS, GO:0031201=ISS, GO:0008021=IEA, GO:0005544=ISS, GO:0005737=ISS, GO:0008104=ISS, GO:0045956=ISS, GO:0015630=IDA, GO:0032024=ISS} calcium ion-dependent exocytosis of neurotransmitter, positive regulation of calcium ion-dependent exocytosis, positive regulation of insulin secretion, positive regulation of vesicle fusion, protein localization SNARE complex, cytoplasm, microtubule cytoskeleton, plasma membrane, synaptic vesicle calcium-dependent phospholipid binding, syntaxin binding, transporter activity Human DOCK1 GOC UniProtKB {GO:0005515=PMID:20936779, GO:0017124=GO_REF:0000037, GO:0007264=GO_REF:0000002, GO:0006915=GO_REF:0000037, GO:0006911=PMID:9548255, GO:0005829=Reactome:REACT_160134, GO:0043547=PMID:9808620, GO:0005085=GO_REF:0000037, GO:0007165=PMID:8661160, GO:0005737=PMID:8661160, GO:0016477=GO_REF:0000019, GO:0016020=GO_REF:0000039, GO:0007596=Reactome:REACT_604, GO:0007229=PMID:9808620, GO:0007411=Reactome:REACT_18266, GO:0045087=Reactome:REACT_6802, GO:0038096=Reactome:REACT_160123, GO:0005096=PMID:9808620} Q14185 Dedicator of cytokinesis protein 1 protein 20130413 {GO:0005515=IPI, GO:0017124=IEA, GO:0007264=IEA, GO:0006915=IEA, GO:0006911=TAS, GO:0005829=TAS, GO:0043547=TAS, GO:0005085=IEA, GO:0007165=TAS, GO:0005737=TAS, GO:0016477=IEA, GO:0016020=IEA, GO:0007596=TAS, GO:0007229=TAS, GO:0007411=TAS, GO:0045087=TAS, GO:0038096=TAS, GO:0005096=TAS} Fc-gamma receptor signaling pathway involved in phagocytosis, apoptotic process, axon guidance, blood coagulation, cell migration, innate immune response, integrin-mediated signaling pathway, phagocytosis, engulfment, positive regulation of GTPase activity, signal transduction, small GTPase mediated signal transduction cytoplasm, cytosol, membrane GTPase activator activity, SH3 domain binding, guanyl-nucleotide exchange factor activity, protein binding Human DOCK10 ENSEMBL UniProtKB {GO:0005085=GO_REF:0000002, GO:0005543=GO_REF:0000002, GO:0007264=GO_REF:0000002, GO:0017048=GO_REF:0000019, GO:0005089=GO_REF:0000019} Q96BY6 Dedicator of cytokinesis protein 10 protein 20130413 {GO:0005085=IEA, GO:0005543=IEA, GO:0007264=IEA, GO:0017048=IEA, GO:0005089=IEA} small GTPase mediated signal transduction Rho GTPase binding, Rho guanyl-nucleotide exchange factor activity, guanyl-nucleotide exchange factor activity, phospholipid binding Human Ensembl:ENSMUSP00000077099 DOCK11 Reactome UniProtKB {GO:0005085=GO_REF:0000002, GO:0005543=GO_REF:0000002, GO:0007596=Reactome:REACT_604, GO:0007264=GO_REF:0000002, GO:0017048=GO_REF:0000019, GO:0005089=GO_REF:0000019, GO:0005829=Reactome:REACT_25140} Q5JSL3 Dedicator of cytokinesis protein 11 protein 20130301 {GO:0005085=IEA, GO:0005543=IEA, GO:0007596=TAS, GO:0007264=IEA, GO:0017048=IEA, GO:0005089=IEA, GO:0005829=TAS} blood coagulation, small GTPase mediated signal transduction cytosol Rho GTPase binding, Rho guanyl-nucleotide exchange factor activity, guanyl-nucleotide exchange factor activity, phospholipid binding Human DOCK2 Reactome UniProtKB {GO:0030036=PMID:12176041, GO:0007264=GO_REF:0000002, GO:0046633=GO_REF:0000019, GO:0005829=Reactome:REACT_11090, GO:0005085=GO_REF:0000002, GO:0050766=GO_REF:0000024, GO:0042608=PMID:12176041, GO:0006935=GO_REF:0000019, GO:0007010=GO_REF:0000019, GO:0016032=Reactome:REACT_6185, GO:0005856=GO_REF:0000039, GO:0030675=GO_REF:0000019, GO:0030676=PMID:10559471, GO:0001771=GO_REF:0000019, GO:0009055=GO_REF:0000002, GO:0045059=GO_REF:0000019, GO:0012505=GO_REF:0000039, GO:0050690=Reactome:REACT_11068, GO:0044351=GO_REF:0000024, GO:0016020=GO_REF:0000037, GO:0001768=GO_REF:0000019, GO:0045060=GO_REF:0000019, GO:0002277=GO_REF:0000024, GO:0001766=GO_REF:0000019, GO:0020037=GO_REF:0000002} Q92608 Dedicator of cytokinesis protein 2 protein 20130213 {GO:0030036=TAS, GO:0007264=IEA, GO:0046633=IEA, GO:0005829=TAS, GO:0005085=IEA, GO:0050766=ISS, GO:0042608=IDA, GO:0006935=IEA, GO:0007010=IEA, GO:0016032=TAS, GO:0005856=IEA, GO:0030675=IEA, GO:0030676=IDA, GO:0001771=IEA, GO:0009055=IEA, GO:0045059=IEA, GO:0012505=IEA, GO:0050690=TAS, GO:0044351=ISS, GO:0016020=IEA, GO:0001768=IEA, GO:0045060=IEA, GO:0002277=ISS, GO:0001766=IEA, GO:0020037=IEA} actin cytoskeleton organization, alpha-beta T cell proliferation, chemotaxis, cytoskeleton organization, establishment of T cell polarity, immunological synapse formation, macropinocytosis, membrane raft polarization, myeloid dendritic cell activation involved in immune response, negative thymic T cell selection, positive regulation of phagocytosis, positive thymic T cell selection, regulation of defense response to virus by virus, small GTPase mediated signal transduction, viral reproduction cytoskeleton, cytosol, endomembrane system, membrane Rac GTPase activator activity, Rac guanyl-nucleotide exchange factor activity, T cell receptor binding, electron carrier activity, guanyl-nucleotide exchange factor activity, heme binding Human DOCK3 HPA UniProtKB {GO:0005515=PMID:17474147, GO:0005085=GO_REF:0000037, GO:0005737=GO_REF:0000052, GO:0017124=GO_REF:0000037, GO:0007264=GO_REF:0000002} Q8IZD9 Dedicator of cytokinesis protein 3 protein 20110516 {GO:0005515=IPI, GO:0005085=IEA, GO:0005737=IDA, GO:0017124=IEA, GO:0007264=IEA} small GTPase mediated signal transduction cytoplasm SH3 domain binding, guanyl-nucleotide exchange factor activity, protein binding Human DOCK4 GOC UniProtKB {GO:0005515=PMID:16464467, GO:0030971=PMID:20679435, GO:0017124=GO_REF:0000037, GO:0007264=GO_REF:0000002, GO:0032420=PMID:16464467, GO:0032421=PMID:16464467, GO:0030165=PMID:16464467, GO:0032855=PMID:16464467, GO:0012505=GO_REF:0000039, GO:0005829=PMID:20679435, GO:0005085=GO_REF:0000037, GO:0048365=PMID:16464467, GO:0016020=PMID:20679435, GO:0060326=PMID:20679435, GO:0030675=PMID:16464467} Q8N1I0 Dedicator of cytokinesis protein 4 protein 20130413 {GO:0005515=IPI, GO:0030971=IPI, GO:0017124=IEA, GO:0007264=IEA, GO:0032420=ISS, GO:0032421=ISS, GO:0030165=IPI, GO:0032855=IDA, GO:0012505=IEA, GO:0005829=IDA, GO:0005085=IEA, GO:0048365=IDA, GO:0016020=IDA, GO:0060326=IMP, GO:0030675=IDA} cell chemotaxis, positive regulation of Rac GTPase activity, small GTPase mediated signal transduction cytosol, endomembrane system, membrane, stereocilium, stereocilium bundle PDZ domain binding, Rac GTPase activator activity, Rac GTPase binding, SH3 domain binding, guanyl-nucleotide exchange factor activity, protein binding, receptor tyrosine kinase binding Human DOCK5 HPA UniProtKB {GO:0005085=GO_REF:0000024, GO:0005737=GO_REF:0000052, GO:0007264=GO_REF:0000002} Q9H7D0 Dedicator of cytokinesis protein 5 protein 20090616 {GO:0005085=ISS, GO:0005737=IDA, GO:0007264=IEA} small GTPase mediated signal transduction cytoplasm guanyl-nucleotide exchange factor activity Human DOCK6 Reactome UniProtKB {GO:0005085=GO_REF:0000037, GO:0048471=GO_REF:0000039, GO:0007596=Reactome:REACT_604, GO:0007264=GO_REF:0000002, GO:0005829=Reactome:REACT_25140} Q96HP0 Dedicator of cytokinesis protein 6 protein 20130301 {GO:0005085=IEA, GO:0048471=IEA, GO:0007596=TAS, GO:0007264=IEA, GO:0005829=TAS} blood coagulation, small GTPase mediated signal transduction cytosol, perinuclear region of cytoplasm guanyl-nucleotide exchange factor activity Human DOCK7 BHF-UCL UniProtKB {GO:0030424=PMID:16982419, GO:0043005=PMID:16982419, GO:0007264=GO_REF:0000002, GO:0045178=PMID:16982419, GO:0000226=PMID:16982419, GO:0045200=PMID:16982419, GO:0007409=PMID:16982419, GO:0032863=PMID:16982419, GO:0031175=PMID:16982419, GO:0030426=PMID:16982419, GO:0005085=GO_REF:0000037, GO:0048365=PMID:16982419, GO:0033138=PMID:16982419, GO:0008180=PMID:18850735, GO:0043473=GO_REF:0000019} Q96N67 Dedicator of cytokinesis protein 7 protein 20080204 {GO:0030424=TAS, GO:0043005=TAS, GO:0007264=IEA, GO:0045178=TAS, GO:0000226=IMP, GO:0045200=IMP, GO:0007409=IMP, GO:0032863=IDA, GO:0031175=IMP, GO:0030426=TAS, GO:0005085=IEA, GO:0048365=IDA, GO:0033138=IMP, GO:0008180=IDA, GO:0043473=IEA} activation of Rac GTPase activity, axonogenesis, establishment of neuroblast polarity, microtubule cytoskeleton organization, neuron projection development, pigmentation, positive regulation of peptidyl-serine phosphorylation, small GTPase mediated signal transduction axon, basal part of cell, growth cone, neuron projection, signalosome Rac GTPase binding, guanyl-nucleotide exchange factor activity Human DOCK8 Reactome UniProtKB {GO:0005085=GO_REF:0000037, GO:0007596=Reactome:REACT_604, GO:0007264=GO_REF:0000002, GO:0005829=Reactome:REACT_25140} Q8NF50 Dedicator of cytokinesis protein 8 protein 20130301 {GO:0005085=IEA, GO:0007596=TAS, GO:0007264=IEA, GO:0005829=TAS} blood coagulation, small GTPase mediated signal transduction cytosol guanyl-nucleotide exchange factor activity Human DOCK9 IntAct UniProtKB {GO:0005515=PMID:18729074, GO:0005085=GO_REF:0000002, GO:0008150=GO_REF:0000015, GO:0005543=GO_REF:0000002, GO:0016020=GO_REF:0000037, GO:0007596=Reactome:REACT_604, GO:0007264=GO_REF:0000002, GO:0017048=GO_REF:0000019, GO:0005575=GO_REF:0000015, GO:0005089=GO_REF:0000019, GO:0005829=Reactome:REACT_25140, GO:0012505=GO_REF:0000039} Q9BZ29 Dedicator of cytokinesis protein 9 protein 20130415 {GO:0005515=IPI, GO:0005085=IEA, GO:0008150=ND, GO:0005543=IEA, GO:0016020=IEA, GO:0007596=TAS, GO:0007264=IEA, GO:0017048=IEA, GO:0005575=ND, GO:0005089=IEA, GO:0005829=TAS, GO:0012505=IEA} biological_process, blood coagulation, small GTPase mediated signal transduction cellular_component, cytosol, endomembrane system, membrane Rho GTPase binding, Rho guanyl-nucleotide exchange factor activity, guanyl-nucleotide exchange factor activity, phospholipid binding, protein binding Human UniProtKB:Q15796 DOHH Reactome UniProtKB {GO:0005515=PMID:17213197, GO:0008612=Reactome:REACT_12469, GO:0005575=GO_REF:0000015, GO:0019135=Reactome:REACT_12479, GO:0044267=Reactome:REACT_17015, GO:0046872=GO_REF:0000037, GO:0043687=Reactome:REACT_22161, GO:0005829=Reactome:REACT_12479} Q9BU89 Deoxyhypusine hydroxylase protein 20071128 {GO:0005515=IPI, GO:0008612=TAS, GO:0005575=ND, GO:0019135=TAS, GO:0044267=TAS, GO:0046872=IEA, GO:0043687=TAS, GO:0005829=TAS} cellular protein metabolic process, peptidyl-lysine modification to hypusine, post-translational protein modification cellular_component, cytosol deoxyhypusine monooxygenase activity, metal ion binding, protein binding Human DOK1 IntAct UniProtKB {GO:0005515=PMID:22190034, GO:0008286=Reactome:REACT_498, GO:0007165=PMID:9008160, GO:0048471=GO_REF:0000039, GO:0005543=GO_REF:0000002, GO:0005158=GO_REF:0000002, GO:0007265=GO_REF:0000019, GO:0005057=GO_REF:0000019, GO:0007169=PMID:9008160, GO:0007166=PMID:10799545, GO:0007243=GO_REF:0000019, GO:0005829=Reactome:REACT_2120} Q99704 Docking protein 1 protein 20130415 {GO:0005515=IPI, GO:0008286=TAS, GO:0007165=TAS, GO:0048471=IEA, GO:0005543=IEA, GO:0005158=IEA, GO:0007265=IEA, GO:0005057=IEA, GO:0007169=TAS, GO:0007166=TAS, GO:0007243=IEA, GO:0005829=TAS} Ras protein signal transduction, cell surface receptor signaling pathway, insulin receptor signaling pathway, intracellular protein kinase cascade, signal transduction, transmembrane receptor protein tyrosine kinase signaling pathway cytosol, perinuclear region of cytoplasm insulin receptor binding, phospholipid binding, protein binding, receptor signaling protein activity Human UniProtKB:Q9Q2G4 DOK2 Reactome UniProtKB {GO:0007165=PMID:9478921, GO:0005543=GO_REF:0000002, GO:0007596=Reactome:REACT_604, GO:0005158=GO_REF:0000002, GO:0005068=GO_REF:0000019, GO:0007265=GO_REF:0000019, GO:0005057=GO_REF:0000019, GO:0050900=Reactome:REACT_12051, GO:0007166=PMID:10799545, GO:0005829=Reactome:REACT_12575} O60496 Docking protein 2 protein 20071203 {GO:0007165=TAS, GO:0005543=IEA, GO:0007596=TAS, GO:0005158=IEA, GO:0005068=IEA, GO:0007265=IEA, GO:0005057=IEA, GO:0050900=TAS, GO:0007166=TAS, GO:0005829=TAS} Ras protein signal transduction, blood coagulation, cell surface receptor signaling pathway, leukocyte migration, signal transduction cytosol insulin receptor binding, phospholipid binding, receptor signaling protein activity, transmembrane receptor protein tyrosine kinase adaptor activity Human DOK3 UniProtKB UniProtKB {GO:0005737=GO_REF:0000039, GO:0005543=GO_REF:0000002, GO:0005886=GO_REF:0000039, GO:0005158=GO_REF:0000002, GO:0007265=GO_REF:0000019} Q7L591 Docking protein 3 protein 20130413 {GO:0005737=IEA, GO:0005543=IEA, GO:0005886=IEA, GO:0005158=IEA, GO:0007265=IEA} Ras protein signal transduction cytoplasm, plasma membrane insulin receptor binding, phospholipid binding Human UniProtKB-SubCell:SL-0039 DOK4 ENSEMBL UniProtKB {GO:0005543=GO_REF:0000002, GO:0000165=GO_REF:0000019, GO:0005158=GO_REF:0000002, GO:0005057=GO_REF:0000019, GO:0007169=GO_REF:0000019, GO:0007399=GO_REF:0000019} Q8TEW6 Docking protein 4 protein 20130413 {GO:0005543=IEA, GO:0000165=IEA, GO:0005158=IEA, GO:0005057=IEA, GO:0007169=IEA, GO:0007399=IEA} MAPK cascade, nervous system development, transmembrane receptor protein tyrosine kinase signaling pathway insulin receptor binding, phospholipid binding, receptor signaling protein activity Human Ensembl:ENSMUSP00000043554 DOK5 ENSEMBL UniProtKB {GO:0005543=GO_REF:0000002, GO:0000165=GO_REF:0000019, GO:0005158=GO_REF:0000002, GO:0005057=GO_REF:0000019, GO:0007169=GO_REF:0000019, GO:0007399=GO_REF:0000019} Q9P104 Docking protein 5 protein 20130413 {GO:0005543=IEA, GO:0000165=IEA, GO:0005158=IEA, GO:0005057=IEA, GO:0007169=IEA, GO:0007399=IEA} MAPK cascade, nervous system development, transmembrane receptor protein tyrosine kinase signaling pathway insulin receptor binding, phospholipid binding, receptor signaling protein activity Human Ensembl:ENSMUSP00000029075 DOK6 InterPro UniProtKB {GO:0005543=GO_REF:0000002, GO:0005158=GO_REF:0000002} Q6PKX4 Docking protein 6 protein 20130413 {GO:0005543=IEA, GO:0005158=IEA} insulin receptor binding, phospholipid binding Human InterPro:IPR001849 DOK7 UniProtKB UniProtKB {GO:0031594=GO_REF:0000019, GO:0030054=GO_REF:0000037, GO:0005543=GO_REF:0000002, GO:0019901=PMID:20603078, GO:0005886=GO_REF:0000039, GO:0007528=GO_REF:0000019, GO:0061098=PMID:20603078, GO:0005158=GO_REF:0000002, GO:0043113=GO_REF:0000019, GO:0035091=GO_REF:0000019} Q18PE1 Protein Dok-7 protein 20110610 {GO:0031594=IEA, GO:0030054=IEA, GO:0005543=IEA, GO:0019901=IDA, GO:0005886=IEA, GO:0007528=IEA, GO:0061098=IDA, GO:0005158=IEA, GO:0043113=IEA, GO:0035091=IEA} neuromuscular junction development, positive regulation of protein tyrosine kinase activity, receptor clustering cell junction, neuromuscular junction, plasma membrane insulin receptor binding, phosphatidylinositol binding, phospholipid binding, protein kinase binding Human DOLK Reactome UniProtKB {GO:0004168=PMID:12213788, GO:0005789=Reactome:REACT_22276, GO:0030176=PMID:16923818, GO:0006488=Reactome:REACT_22433, GO:0044267=Reactome:REACT_17015, GO:0006489=Reactome:REACT_22230, GO:0043048=PMID:12213788, GO:0043687=Reactome:REACT_22161, GO:0018279=Reactome:REACT_22426} Q9UPQ8 Dolichol kinase protein 20130301 {GO:0004168=IDA, GO:0005789=TAS, GO:0030176=IDA, GO:0006488=TAS, GO:0044267=TAS, GO:0006489=TAS, GO:0043048=IDA, GO:0043687=TAS, GO:0018279=TAS} cellular protein metabolic process, dolichol-linked oligosaccharide biosynthetic process, dolichyl diphosphate biosynthetic process, dolichyl monophosphate biosynthetic process, post-translational protein modification, protein N-linked glycosylation via asparagine endoplasmic reticulum membrane, integral to endoplasmic reticulum membrane dolichol kinase activity Human DOLPP1 Reactome UniProtKB {GO:0005789=Reactome:REACT_22114, GO:0030176=GO_REF:0000024, GO:0006487=GO_REF:0000024, GO:0047874=GO_REF:0000024, GO:0006488=Reactome:REACT_22433, GO:0044267=Reactome:REACT_17015, GO:0006489=Reactome:REACT_22230, GO:0043687=Reactome:REACT_22161, GO:0018279=Reactome:REACT_22426} Q86YN1 Dolichyldiphosphatase 1 protein 20130301 {GO:0005789=TAS, GO:0030176=ISS, GO:0006487=ISS, GO:0047874=ISS, GO:0006488=TAS, GO:0044267=TAS, GO:0006489=TAS, GO:0043687=TAS, GO:0018279=TAS} cellular protein metabolic process, dolichol-linked oligosaccharide biosynthetic process, dolichyl diphosphate biosynthetic process, post-translational protein modification, protein N-linked glycosylation, protein N-linked glycosylation via asparagine endoplasmic reticulum membrane, integral to endoplasmic reticulum membrane dolichyldiphosphatase activity Human DOM3Z UniProtKB UniProtKB {GO:0000166=GO_REF:0000037, GO:0046872=GO_REF:0000037} O77932 Protein Dom3Z protein 20130413 {GO:0000166=IEA, GO:0046872=IEA} metal ion binding, nucleotide binding Human UniProtKB-KW:KW-0479 DONSON UniProtKB UniProtKB {GO:0008150=GO_REF:0000015, GO:0003674=GO_REF:0000015, GO:0005634=GO_REF:0000039, GO:0007275=GO_REF:0000037, GO:0005575=GO_REF:0000015} Q9NYP3 Protein downstream neighbor of Son protein 20061026 {GO:0008150=ND, GO:0003674=ND, GO:0005634=IEA, GO:0007275=IEA, GO:0005575=ND} biological_process, multicellular organismal development cellular_component, nucleus molecular_function Human DOPEY1 HGNC UniProtKB {GO:0000139=PMID:16301316, GO:0015031=GO_REF:0000037, GO:0007029=PMID:16301316, GO:0006895=PMID:16301316} Q5TA12 Protein dopey-1 protein 20060201 {GO:0000139=ISS, GO:0015031=IEA, GO:0007029=ISS, GO:0006895=ISS} Golgi to endosome transport, endoplasmic reticulum organization, protein transport Golgi membrane Human UniProtKB:Q03921 DOPEY2 HGNC UniProtKB {GO:0003674=GO_REF:0000015, GO:0000139=PMID:16301316, GO:0007275=PMID:10950924, GO:0015031=GO_REF:0000037, GO:0007029=PMID:16301316, GO:0006895=PMID:16301316} Q9Y3R5 Protein dopey-2 protein 20060201 {GO:0003674=ND, GO:0000139=ISS, GO:0007275=NAS, GO:0015031=IEA, GO:0007029=ISS, GO:0006895=ISS} Golgi to endosome transport, endoplasmic reticulum organization, multicellular organismal development, protein transport Golgi membrane molecular_function Human UniProtKB:Q03921 DOT1L GOC UniProtKB {GO:0005515=PMID:20153263, GO:0034968=PMID:17707234, GO:0046425=PMID:22002246, GO:0005634=GO_REF:0000039, GO:2000677=PMID:22002246, GO:0003677=GO_REF:0000037, GO:0018024=PMID:17707234} Q8TEK3 Histone-lysine N-methyltransferase, H3 lysine-79 specific protein 20130413 {GO:0005515=IPI, GO:0034968=IDA, GO:0046425=IDA, GO:0005634=IEA, GO:2000677=IMP, GO:0003677=IEA, GO:0018024=IDA} histone lysine methylation, regulation of JAK-STAT cascade, regulation of transcription regulatory region DNA binding nucleus DNA binding, histone-lysine N-methyltransferase activity, protein binding Human DPAGT1 Reactome UniProtKB {GO:0016757=GO_REF:0000037, GO:0019408=PMID:8179616, GO:0030176=PMID:12872255, GO:0006047=GO_REF:0000019, GO:0051259=GO_REF:0000024, GO:0043231=PMID:12872255, GO:0016020=PMID:8179616, GO:0003975=PMID:12872255, GO:0005789=Reactome:REACT_22147, GO:0016021=GO_REF:0000024, GO:0006487=PMID:19549906, GO:0006488=Reactome:REACT_22433, GO:0044267=Reactome:REACT_17015, GO:0043687=Reactome:REACT_22161, GO:0018279=Reactome:REACT_22426, GO:0008963=GO_REF:0000002} Q9H3H5 UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase protein 20130301 {GO:0016757=IEA, GO:0019408=IDA, GO:0030176=NAS, GO:0006047=IEA, GO:0051259=ISS, GO:0043231=IDA, GO:0016020=IDA, GO:0003975=IMP, GO:0005789=TAS, GO:0016021=ISS, GO:0006487=IMP, GO:0006488=TAS, GO:0044267=TAS, GO:0043687=TAS, GO:0018279=TAS, GO:0008963=IEA} UDP-N-acetylglucosamine metabolic process, cellular protein metabolic process, dolichol biosynthetic process, dolichol-linked oligosaccharide biosynthetic process, post-translational protein modification, protein N-linked glycosylation, protein N-linked glycosylation via asparagine, protein oligomerization endoplasmic reticulum membrane, integral to endoplasmic reticulum membrane, integral to membrane, intracellular membrane-bounded organelle, membrane UDP-N-acetylglucosamine-dolichyl-phosphate N-acetylglucosaminephosphotransferase activity, phospho-N-acetylmuramoyl-pentapeptide-transferase activity, transferase activity, transferring glycosyl groups Human DPCD ENSEMBL UniProtKB {GO:0007368=GO_REF:0000019, GO:0021670=GO_REF:0000019, GO:0003351=GO_REF:0000019, GO:0060972=GO_REF:0000019, GO:0030317=GO_REF:0000019, GO:0007283=GO_REF:0000019, GO:0021678=GO_REF:0000019} Q9BVM2 Protein DPCD protein 20130413 {GO:0007368=IEA, GO:0021670=IEA, GO:0003351=IEA, GO:0060972=IEA, GO:0030317=IEA, GO:0007283=IEA, GO:0021678=IEA} determination of left/right symmetry, epithelial cilium movement, lateral ventricle development, left/right pattern formation, sperm motility, spermatogenesis, third ventricle development Human Ensembl:ENSMUSP00000045683 DPCR1 UniProtKB UniProtKB {GO:0016021=GO_REF:0000037} Q3MIW9 Diffuse panbronchiolitis critical region protein 1 protein 20130413 {GO:0016021=IEA} integral to membrane Human UniProtKB-KW:KW-0812 DPEP1 IntAct UniProtKB {GO:0019369=Reactome:REACT_147851, GO:0005515=PMID:16189514, GO:0034235=GO_REF:0000024, GO:0071732=GO_REF:0000024, GO:0005886=Reactome:REACT_15395, GO:0031528=GO_REF:0000039, GO:0006749=PMID:20031578, GO:0031225=GO_REF:0000037, GO:0044281=Reactome:REACT_111217, GO:0005615=GO_REF:0000024, GO:0006691=Reactome:REACT_150420, GO:0050667=PMID:20031578, GO:0072341=PMID:20031578, GO:0072340=PMID:12144777, GO:0016324=GO_REF:0000039, GO:0070573=PMID:19879002, GO:0006508=GO_REF:0000037, GO:0071277=GO_REF:0000024, GO:0030336=PMID:20824289, GO:0045177=PMID:20824289, GO:0016805=GO_REF:0000002, GO:0016999=PMID:8737157, GO:0008235=PMID:2303490, GO:0008270=PMID:19879002, GO:0008239=GO_REF:0000002} P16444 Dipeptidase 1 protein 20130415 {GO:0019369=TAS, GO:0005515=IPI, GO:0034235=ISS, GO:0071732=ISS, GO:0005886=TAS, GO:0031528=IEA, GO:0006749=TAS, GO:0031225=IEA, GO:0044281=TAS, GO:0005615=ISS, GO:0006691=TAS, GO:0050667=IDA, GO:0072341=IDA, GO:0072340=TAS, GO:0016324=IEA, GO:0070573=IDA, GO:0006508=IEA, GO:0071277=ISS, GO:0030336=IMP, GO:0045177=IDA, GO:0016805=IEA, GO:0016999=IDA, GO:0008235=TAS, GO:0008270=IDA, GO:0008239=IEA} antibiotic metabolic process, arachidonic acid metabolic process, cellular lactam catabolic process, cellular response to calcium ion, cellular response to nitric oxide, glutathione metabolic process, homocysteine metabolic process, leukotriene metabolic process, negative regulation of cell migration, proteolysis, small molecule metabolic process anchored to membrane, apical part of cell, apical plasma membrane, extracellular space, microvillus membrane, plasma membrane GPI anchor binding, dipeptidase activity, dipeptidyl-peptidase activity, metallodipeptidase activity, metalloexopeptidase activity, modified amino acid binding, protein binding, zinc ion binding Human UniProtKB:Q96EK5 DPEP2 Reactome UniProtKB {GO:0019369=Reactome:REACT_147851, GO:0005886=Reactome:REACT_15395, GO:0008235=GO_REF:0000002, GO:0006508=GO_REF:0000037, GO:0044281=Reactome:REACT_111217, GO:0031225=GO_REF:0000037, GO:0008239=GO_REF:0000002, GO:0006691=Reactome:REACT_150420, GO:0016805=GO_REF:0000037, GO:0046872=GO_REF:0000037} Q9H4A9 Dipeptidase 2 protein 20130301 {GO:0019369=TAS, GO:0005886=TAS, GO:0008235=IEA, GO:0006508=IEA, GO:0044281=TAS, GO:0031225=IEA, GO:0008239=IEA, GO:0006691=TAS, GO:0016805=IEA, GO:0046872=IEA} arachidonic acid metabolic process, leukotriene metabolic process, proteolysis, small molecule metabolic process anchored to membrane, plasma membrane dipeptidase activity, dipeptidyl-peptidase activity, metal ion binding, metalloexopeptidase activity Human DPEP3 UniProtKB UniProtKB {GO:0006508=GO_REF:0000019, GO:0008235=GO_REF:0000002, GO:0031225=GO_REF:0000037, GO:0008239=GO_REF:0000002, GO:0016805=GO_REF:0000037, GO:0046872=GO_REF:0000037, GO:0007140=GO_REF:0000024} Q9H4B8 Dipeptidase 3 protein 20120815 {GO:0006508=IEA, GO:0008235=IEA, GO:0031225=IEA, GO:0008239=IEA, GO:0016805=IEA, GO:0046872=IEA, GO:0007140=ISS} male meiosis, proteolysis anchored to membrane dipeptidase activity, dipeptidyl-peptidase activity, metal ion binding, metalloexopeptidase activity Human UniProtKB:Q9DA79 DPF1 PINC UniProtKB {GO:0005737=GO_REF:0000039, GO:0006355=GO_REF:0000037, GO:0071565=GO_REF:0000024, GO:0008270=GO_REF:0000002, GO:0006917=PMID:8812431, GO:0003676=GO_REF:0000002, GO:0006351=GO_REF:0000037, GO:0007399=GO_REF:0000024} Q92782 Zinc finger protein neuro-d4 protein 20030904 {GO:0005737=IEA, GO:0006355=IEA, GO:0071565=ISS, GO:0008270=IEA, GO:0006917=TAS, GO:0003676=IEA, GO:0006351=IEA, GO:0007399=ISS} induction of apoptosis, nervous system development, regulation of transcription, DNA-dependent, transcription, DNA-dependent cytoplasm, nBAF complex nucleic acid binding, zinc ion binding Human DPF2 HPA UniProtKB {GO:0005813=GO_REF:0000052, GO:0005737=GO_REF:0000052, GO:0006355=GO_REF:0000037, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0008270=GO_REF:0000002, GO:0006917=PMID:8812431, GO:0097190=PMID:7961935, GO:0006351=GO_REF:0000037, GO:0043231=GO_REF:0000052} Q92785 Zinc finger protein ubi-d4 protein 20101115 {GO:0005813=IDA, GO:0005737=IDA, GO:0006355=IEA, GO:0005730=IDA, GO:0005634=IDA, GO:0008270=IEA, GO:0006917=TAS, GO:0097190=TAS, GO:0006351=IEA, GO:0043231=IDA} apoptotic signaling pathway, induction of apoptosis, regulation of transcription, DNA-dependent, transcription, DNA-dependent centrosome, cytoplasm, intracellular membrane-bounded organelle, nucleolus, nucleus zinc ion binding Human DPF3 UniProtKB UniProtKB {GO:0008150=GO_REF:0000015, GO:0071565=GO_REF:0000024, GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000029, GO:0008270=PMID:8812431, GO:0006351=GO_REF:0000037, GO:0007399=GO_REF:0000019, GO:0016568=GO_REF:0000037} Q92784 Zinc finger protein DPF3 protein 20100126 {GO:0008150=ND, GO:0071565=ISS, GO:0006355=IEA, GO:0005634=NAS, GO:0008270=NAS, GO:0006351=IEA, GO:0007399=IEA, GO:0016568=IEA} biological_process, chromatin modification, nervous system development, regulation of transcription, DNA-dependent, transcription, DNA-dependent nBAF complex, nucleus zinc ion binding Human UniProtKB:P58269 DPH1 PINC UniProtKB {GO:0005737=GO_REF:0000039, GO:0008283=GO_REF:0000019, GO:0005634=GO_REF:0000039, GO:0006412=PMID:8603384, GO:0017183=GO_REF:0000002} Q9BZG8 Diphthamide biosynthesis protein 1 protein 20030904 {GO:0005737=IEA, GO:0008283=IEA, GO:0005634=IEA, GO:0006412=TAS, GO:0017183=IEA} cell proliferation, peptidyl-diphthamide biosynthetic process from peptidyl-histidine, translation cytoplasm, nucleus Human DPH2 InterPro UniProtKB {GO:0005737=GO_REF:0000002, GO:0017183=GO_REF:0000002} Q9BQC3 Diphthamide biosynthesis protein 2 protein 20130413 {GO:0005737=IEA, GO:0017183=IEA} peptidyl-diphthamide biosynthetic process from peptidyl-histidine cytoplasm Human InterPro:IPR002728|InterPro:IPR010014 DPH3 HPA UniProtKB {GO:0005515=PMID:14980502, GO:0005737=GO_REF:0000052, GO:0005730=GO_REF:0000052, GO:0050709=PMID:14980502, GO:0051099=PMID:14980502, GO:0005634=GO_REF:0000052, GO:0017183=GO_REF:0000024, GO:0046872=GO_REF:0000037} Q96FX2 DPH3 homolog protein 20101115 {GO:0005515=IPI, GO:0005737=IDA, GO:0005730=IDA, GO:0050709=IDA, GO:0051099=IDA, GO:0005634=IDA, GO:0017183=ISS, GO:0046872=IEA} negative regulation of protein secretion, peptidyl-diphthamide biosynthetic process from peptidyl-histidine, positive regulation of binding cytoplasm, nucleolus, nucleus metal ion binding, protein binding Human DPH5 UniProtKB UniProtKB {GO:0004164=PMID:15485916, GO:0008168=GO_REF:0000002, GO:0005575=GO_REF:0000015, GO:0017183=PMID:15485916} Q9H2P9 Diphthine synthase protein 20081106 {GO:0004164=NAS, GO:0008168=IEA, GO:0005575=ND, GO:0017183=NAS} peptidyl-diphthamide biosynthetic process from peptidyl-histidine cellular_component diphthine synthase activity, methyltransferase activity Human DPM1 HGNC UniProtKB {GO:0006501=Reactome:REACT_1853, GO:0005515=PMID:10835346, GO:0004582=PMID:9535917, GO:0033185=PMID:9724629, GO:0016757=GO_REF:0000038, GO:0043178=GO_REF:0000019, GO:0005783=PMID:9724629, GO:0019348=PMID:9724629, GO:0019673=GO_REF:0000019, GO:0005537=GO_REF:0000019, GO:0035269=PMID:9535917, GO:0035268=PMID:9535917, GO:0004169=PMID:9535917, GO:0016020=PMID:9535917, GO:0005789=Reactome:REACT_2036, GO:0006488=Reactome:REACT_22433, GO:0044267=Reactome:REACT_17015, GO:0006506=PMID:9535917, GO:0043687=Reactome:REACT_22161, GO:0018279=Reactome:REACT_22426} O60762 Dolichol-phosphate mannosyltransferase protein 20070403 {GO:0006501=TAS, GO:0005515=IPI, GO:0004582=IDA, GO:0033185=IDA, GO:0016757=IEA, GO:0043178=IEA, GO:0005783=IDA, GO:0019348=IDA, GO:0019673=IEA, GO:0005537=IEA, GO:0035269=IDA, GO:0035268=IDA, GO:0004169=IDA, GO:0016020=IDA, GO:0005789=TAS, GO:0006488=TAS, GO:0044267=TAS, GO:0006506=IDA, GO:0043687=TAS, GO:0018279=TAS} C-terminal protein lipidation, GDP-mannose metabolic process, GPI anchor biosynthetic process, cellular protein metabolic process, dolichol metabolic process, dolichol-linked oligosaccharide biosynthetic process, post-translational protein modification, protein N-linked glycosylation via asparagine, protein O-linked mannosylation, protein mannosylation dolichol-phosphate-mannose synthase complex, endoplasmic reticulum, endoplasmic reticulum membrane, membrane alcohol binding, dolichyl-phosphate beta-D-mannosyltransferase activity, dolichyl-phosphate-mannose-protein mannosyltransferase activity, mannose binding, protein binding, transferase activity, transferring glycosyl groups Human DPM2 InterPro UniProtKB {GO:0006501=Reactome:REACT_1853, GO:0005515=PMID:10835346, GO:0004582=PMID:10835346, GO:0048471=GO_REF:0000019, GO:0033185=PMID:10835346, GO:0009059=GO_REF:0000002, GO:0019348=GO_REF:0000019, GO:0016254=Reactome:REACT_952, GO:0030176=GO_REF:0000002, GO:0000506=PMID:16280320, GO:0035269=PMID:16280320, GO:0031647=PMID:10835346, GO:0005789=Reactome:REACT_2036, GO:0030234=GO_REF:0000019, GO:0006488=Reactome:REACT_22433, GO:0044267=Reactome:REACT_17015, GO:0006506=PMID:10835346, GO:0043687=Reactome:REACT_22161, GO:0018279=Reactome:REACT_22426} Q5T9C7 Dolichol phosphate-mannose biosynthesis regulatory protein protein 20130413 {GO:0006501=TAS, GO:0005515=IPI, GO:0004582=IDA, GO:0048471=IEA, GO:0033185=IDA, GO:0009059=IEA, GO:0019348=IEA, GO:0016254=TAS, GO:0030176=IEA, GO:0000506=TAS, GO:0035269=TAS, GO:0031647=IPI, GO:0005789=TAS, GO:0030234=IEA, GO:0006488=TAS, GO:0044267=TAS, GO:0006506=IDA, GO:0043687=TAS, GO:0018279=TAS} C-terminal protein lipidation, GPI anchor biosynthetic process, cellular protein metabolic process, dolichol metabolic process, dolichol-linked oligosaccharide biosynthetic process, macromolecule biosynthetic process, post-translational protein modification, preassembly of GPI anchor in ER membrane, protein N-linked glycosylation via asparagine, protein O-linked mannosylation, regulation of protein stability dolichol-phosphate-mannose synthase complex, endoplasmic reticulum membrane, glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex, integral to endoplasmic reticulum membrane, perinuclear region of cytoplasm dolichyl-phosphate beta-D-mannosyltransferase activity, enzyme regulator activity, protein binding Human InterPro:IPR009914 DPM3 Reactome UniProtKB {GO:0006501=Reactome:REACT_1853, GO:0005515=PMID:10835346, GO:0004582=PMID:10835346, GO:0033185=PMID:10835346, GO:0005783=PMID:10835346, GO:0005975=PMID:10835346, GO:0018406=PMID:16280320, GO:0031501=PMID:16280320, GO:0030176=PMID:10835346, GO:0035269=PMID:16280320, GO:0035268=PMID:16280320, GO:0031647=PMID:10835346, GO:0005789=Reactome:REACT_2036, GO:0006488=Reactome:REACT_22433, GO:0044267=Reactome:REACT_17015, GO:0006506=PMID:16280320, GO:0043687=Reactome:REACT_22161, GO:0018279=Reactome:REACT_22426} Q9P2X0 Dolichol-phosphate mannosyltransferase subunit 3 protein 20130213 {GO:0006501=TAS, GO:0005515=IPI, GO:0004582=IDA, GO:0033185=IDA, GO:0005783=IDA, GO:0005975=NAS, GO:0018406=TAS, GO:0031501=TAS, GO:0030176=IDA, GO:0035269=TAS, GO:0035268=TAS, GO:0031647=IPI, GO:0005789=TAS, GO:0006488=TAS, GO:0044267=TAS, GO:0006506=TAS, GO:0043687=TAS, GO:0018279=TAS} C-terminal protein lipidation, GPI anchor biosynthetic process, carbohydrate metabolic process, cellular protein metabolic process, dolichol-linked oligosaccharide biosynthetic process, post-translational protein modification, protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan, protein N-linked glycosylation via asparagine, protein O-linked mannosylation, protein mannosylation, regulation of protein stability dolichol-phosphate-mannose synthase complex, endoplasmic reticulum, endoplasmic reticulum membrane, integral to endoplasmic reticulum membrane, mannosyltransferase complex dolichyl-phosphate beta-D-mannosyltransferase activity, protein binding Human DPP10 MGI UniProtKB {GO:0016020=PMID:12662155, GO:0006508=GO_REF:0000002, GO:0008236=GO_REF:0000002, GO:0016021=GO_REF:0000037, GO:0008239=PMID:12662155} Q8N608 Inactive dipeptidyl peptidase 10 protein 20120515 {GO:0016020=IDA, GO:0006508=IEA, GO:0008236=IEA, GO:0016021=IEA, GO:0008239=IDA} proteolysis integral to membrane, membrane dipeptidyl-peptidase activity, serine-type peptidase activity Human DPP3 HPA UniProtKB {GO:0005737=GO_REF:0000052, GO:0005886=GO_REF:0000052, GO:0004177=GO_REF:0000037, GO:0005730=GO_REF:0000052, GO:0006508=PMID:10387075, GO:0005634=GO_REF:0000052, GO:0008270=PMID:10387075, GO:0008239=PMID:10387075, GO:0008237=GO_REF:0000037} Q9NY33 Dipeptidyl peptidase 3 protein 20110516 {GO:0005737=IDA, GO:0005886=IDA, GO:0004177=IEA, GO:0005730=IDA, GO:0006508=IDA, GO:0005634=IDA, GO:0008270=IDA, GO:0008239=IDA, GO:0008237=IEA} proteolysis cytoplasm, nucleolus, nucleus, plasma membrane aminopeptidase activity, dipeptidyl-peptidase activity, metallopeptidase activity, zinc ion binding Human DPP4 UniProtKB UniProtKB {GO:0005515=PMID:17287217, GO:0008284=PMID:17549790, GO:0004252=GO_REF:0000002, GO:0005886=PMID:16670267, GO:0031295=PMID:10900005, GO:0030139=PMID:10900005, GO:0002020=PMID:16651416, GO:0042803=PMID:14684150, GO:0010716=PMID:16651416, GO:0016324=PMID:15052268, GO:0046581=GO_REF:0000019, GO:0071438=PMID:16651416, GO:0006508=GO_REF:0000037, GO:0007155=GO_REF:0000037, GO:0001666=PMID:16670267, GO:0009986=PMID:10900005, GO:0031258=GO_REF:0000039, GO:0005102=PMID:10900005, GO:0033632=PMID:11772392, GO:0030027=PMID:16651416, GO:0042110=PMID:7594462, GO:0016020=GO_REF:0000002, GO:0043542=PMID:16651416, GO:0004177=GO_REF:0000037, GO:0008236=PMID:14684150, GO:0045121=GO_REF:0000039, GO:0016021=GO_REF:0000037, GO:0008239=PMID:16651416} P27487 Dipeptidyl peptidase 4 protein 20091214 {GO:0005515=IPI, GO:0008284=IDA, GO:0004252=IEA, GO:0005886=IDA, GO:0031295=IDA, GO:0030139=IDA, GO:0002020=IPI, GO:0042803=IPI, GO:0010716=IDA, GO:0016324=IDA, GO:0046581=IEA, GO:0071438=IDA, GO:0006508=IEA, GO:0007155=IEA, GO:0001666=IDA, GO:0009986=IDA, GO:0031258=IEA, GO:0005102=IPI, GO:0033632=IDA, GO:0030027=IDA, GO:0042110=IDA, GO:0016020=IEA, GO:0043542=IDA, GO:0004177=IEA, GO:0008236=IDA, GO:0045121=IEA, GO:0016021=IEA, GO:0008239=IDA} T cell activation, T cell costimulation, cell adhesion, endothelial cell migration, negative regulation of extracellular matrix disassembly, positive regulation of cell proliferation, proteolysis, regulation of cell-cell adhesion mediated by integrin, response to hypoxia apical plasma membrane, cell surface, endocytic vesicle, integral to membrane, intercellular canaliculus, invadopodium membrane, lamellipodium, lamellipodium membrane, membrane, membrane raft, plasma membrane aminopeptidase activity, dipeptidyl-peptidase activity, protease binding, protein binding, protein homodimerization activity, receptor binding, serine-type endopeptidase activity, serine-type peptidase activity Human UniProtKB:Q03135 DPP6 PINC UniProtKB {GO:0008219=GO_REF:0000037, GO:0016020=GO_REF:0000002, GO:0006508=GO_REF:0000002, GO:0008236=GO_REF:0000002, GO:0043266=GO_REF:0000019, GO:0016021=GO_REF:0000037, GO:0008239=PMID:8103397, GO:0019228=GO_REF:0000019} P42658 Dipeptidyl aminopeptidase-like protein 6 protein 20030904 {GO:0008219=IEA, GO:0016020=IEA, GO:0006508=IEA, GO:0008236=IEA, GO:0043266=IEA, GO:0016021=IEA, GO:0008239=TAS, GO:0019228=IEA} cell death, proteolysis, regulation of action potential in neuron, regulation of potassium ion transport integral to membrane, membrane dipeptidyl-peptidase activity, serine-type peptidase activity Human DPP7 UniProtKB UniProtKB {GO:0004177=GO_REF:0000037, GO:0006508=GO_REF:0000019, GO:0016023=GO_REF:0000039, GO:0008236=GO_REF:0000037, GO:0005576=GO_REF:0000039, GO:0008239=GO_REF:0000019, GO:0005764=GO_REF:0000039, GO:0005829=GO_REF:0000019} Q9UHL4 Dipeptidyl peptidase 2 protein 20130413 {GO:0004177=IEA, GO:0006508=IEA, GO:0016023=IEA, GO:0008236=IEA, GO:0005576=IEA, GO:0008239=IEA, GO:0005764=IEA, GO:0005829=IEA} proteolysis cytoplasmic membrane-bounded vesicle, cytosol, extracellular region, lysosome aminopeptidase activity, dipeptidyl-peptidase activity, serine-type peptidase activity Human UniProtKB-SubCell:SL-0088 DPP8 HPA UniProtKB {GO:0006955=PMID:11012666, GO:0005737=GO_REF:0000052, GO:0016020=GO_REF:0000002, GO:0004177=GO_REF:0000037, GO:0005730=GO_REF:0000052, GO:0006508=PMID:11012666, GO:0008236=GO_REF:0000037, GO:0005634=GO_REF:0000052, GO:0008239=PMID:11012666} Q6V1X1 Dipeptidyl peptidase 8 protein 20101115 {GO:0006955=TAS, GO:0005737=IDA, GO:0016020=IEA, GO:0004177=IEA, GO:0005730=IDA, GO:0006508=NAS, GO:0008236=IEA, GO:0005634=IDA, GO:0008239=NAS} immune response, proteolysis cytoplasm, membrane, nucleolus, nucleus aminopeptidase activity, dipeptidyl-peptidase activity, serine-type peptidase activity Human DPP9 HPA UniProtKB {GO:0005737=GO_REF:0000052, GO:0016020=GO_REF:0000002, GO:0004177=GO_REF:0000037, GO:0006508=GO_REF:0000037, GO:0008236=GO_REF:0000037, GO:0005829=GO_REF:0000039} Q86TI2 Dipeptidyl peptidase 9 protein 20110516 {GO:0005737=IDA, GO:0016020=IEA, GO:0004177=IEA, GO:0006508=IEA, GO:0008236=IEA, GO:0005829=IEA} proteolysis cytoplasm, cytosol, membrane aminopeptidase activity, serine-type peptidase activity Human DPPA2 HPA UniProtKB {GO:0031060=GO_REF:0000019, GO:0006355=GO_REF:0000037, GO:0019827=GO_REF:0000019, GO:0003682=GO_REF:0000019, GO:0005634=GO_REF:0000052, GO:2000648=GO_REF:0000019, GO:0060484=GO_REF:0000019, GO:0003676=GO_REF:0000002, GO:0006351=GO_REF:0000037} Q7Z7J5 Developmental pluripotency-associated protein 2 protein 20110516 {GO:0031060=IEA, GO:0006355=IEA, GO:0019827=IEA, GO:0003682=IEA, GO:0005634=IDA, GO:2000648=IEA, GO:0060484=IEA, GO:0003676=IEA, GO:0006351=IEA} lung-associated mesenchyme development, positive regulation of stem cell proliferation, regulation of histone methylation, regulation of transcription, DNA-dependent, stem cell maintenance, transcription, DNA-dependent nucleus chromatin binding, nucleic acid binding Human DPPA3 UniProtKB UniProtKB {GO:2000653=GO_REF:0000024, GO:0005737=PMID:21421998, GO:0001939=GO_REF:0000024, GO:0040016=GO_REF:0000019, GO:1901536=GO_REF:0000024, GO:0005634=PMID:21421998, GO:0001940=GO_REF:0000024, GO:0035064=GO_REF:0000024, GO:0044726=GO_REF:0000024, GO:0016568=GO_REF:0000037} Q6W0C5 Developmental pluripotency-associated protein 3 protein 20121101 {GO:2000653=ISS, GO:0005737=IDA, GO:0001939=ISS, GO:0040016=IEA, GO:1901536=ISS, GO:0005634=IDA, GO:0001940=ISS, GO:0035064=ISS, GO:0044726=ISS, GO:0016568=IEA} chromatin modification, embryonic cleavage, negative regulation of DNA demethylation, protection of DNA demethylation of female pronucleus, regulation of genetic imprinting cytoplasm, female pronucleus, male pronucleus, nucleus methylated histone residue binding NOT Human UniProtKB:Q8QZY3 DPPA4 IntAct UniProtKB {GO:0005515=PMID:16169070, GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0007275=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q7L190 Developmental pluripotency-associated protein 4 protein 20130415 {GO:0005515=IPI, GO:0006355=IEA, GO:0005634=IEA, GO:0007275=IEA, GO:0006351=IEA} multicellular organismal development, regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus protein binding Human UniProtKB:Q99961 DPT BHF-UCL UniProtKB {GO:0031012=PMID:22261194, GO:0008285=GO_REF:0000019, GO:0030199=GO_REF:0000019, GO:0005578=GO_REF:0000039, GO:0007155=GO_REF:0000037} Q07507 Dermatopontin protein 20120228 {GO:0031012=ISS, GO:0008285=IEA, GO:0030199=IEA, GO:0005578=IEA, GO:0007155=IEA} cell adhesion, collagen fibril organization, negative regulation of cell proliferation extracellular matrix, proteinaceous extracellular matrix colocalizes_with Human UniProtKB:P45846 DPY19L1 UniProtKB UniProtKB {GO:0016021=GO_REF:0000037} Q2PZI1 Protein dpy-19 homolog 1 protein 20130413 {GO:0016021=IEA} integral to membrane Human UniProtKB-KW:KW-0812 DPY19L3 UniProtKB UniProtKB {GO:0016021=GO_REF:0000037} Q6ZPD9 Protein dpy-19 homolog 3 protein 20130413 {GO:0016021=IEA} integral to membrane Human UniProtKB-KW:KW-0812 DPY19L4 UniProtKB UniProtKB {GO:0016021=GO_REF:0000037} Q7Z388 Protein dpy-19 homolog 4 protein 20130413 {GO:0016021=IEA} integral to membrane Human UniProtKB-KW:KW-0812 DPY30 HPA UniProtKB {GO:0005515=PMID:19556245, GO:0005802=PMID:19651892, GO:0006355=GO_REF:0000037, GO:0005794=GO_REF:0000039, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0006351=GO_REF:0000037, GO:0042803=PMID:19556245, GO:0042802=PMID:19556245, GO:0035097=PMID:17500065, GO:0048188=PMID:18838538, GO:0016197=PMID:19651892, GO:0051568=PMID:19556245} Q9C005 Protein dpy-30 homolog protein 20111111 {GO:0005515=IPI, GO:0005802=IDA, GO:0006355=IEA, GO:0005794=IEA, GO:0005730=IDA, GO:0005634=IDA, GO:0006351=IEA, GO:0042803=IPI, GO:0042802=IPI, GO:0035097=IDA, GO:0048188=IDA, GO:0016197=IMP, GO:0051568=IDA} endosomal transport, histone H3-K4 methylation, regulation of transcription, DNA-dependent, transcription, DNA-dependent Golgi apparatus, Set1C/COMPASS complex, histone methyltransferase complex, nucleolus, nucleus, trans-Golgi network identical protein binding, protein binding, protein homodimerization activity NOT Human DPYD Reactome UniProtKB {GO:0050661=GO_REF:0000024, GO:0017113=Reactome:REACT_1067, GO:0006214=PMID:1512248, GO:0051539=GO_REF:0000037, GO:0051536=GO_REF:0000002, GO:0006210=PMID:10410956, GO:0050660=GO_REF:0000024, GO:0006212=PMID:18075467, GO:0006222=GO_REF:0000002, GO:0055086=Reactome:REACT_1698, GO:0044281=Reactome:REACT_111217, GO:0046872=GO_REF:0000037, GO:0042803=GO_REF:0000024, GO:0005829=Reactome:REACT_1067, GO:0019483=GO_REF:0000041, GO:0046135=Reactome:REACT_1023, GO:0005737=PMID:1512248, GO:0006145=PMID:11988088, GO:0016491=GO_REF:0000002, GO:0006206=Reactome:REACT_957, GO:0004158=GO_REF:0000002, GO:0006208=GO_REF:0000024} Q12882 "Dihydropyrimidine dehydrogenase ""NADP(+)""" protein 20130213 {GO:0050661=ISS, GO:0017113=TAS, GO:0006214=IDA, GO:0051539=IEA, GO:0051536=IEA, GO:0006210=IDA, GO:0050660=ISS, GO:0006212=IDA, GO:0006222=IEA, GO:0055086=TAS, GO:0044281=TAS, GO:0046872=IEA, GO:0042803=ISS, GO:0005829=TAS, GO:0019483=IEA, GO:0046135=TAS, GO:0005737=IDA, GO:0006145=IMP, GO:0016491=IEA, GO:0006206=TAS, GO:0004158=IEA, GO:0006208=ISS} UMP biosynthetic process, beta-alanine biosynthetic process, nucleobase-containing small molecule metabolic process, purine nucleobase catabolic process, pyrimidine nucleobase catabolic process, pyrimidine nucleobase metabolic process, pyrimidine nucleoside catabolic process, small molecule metabolic process, thymidine catabolic process, thymine catabolic process, uracil catabolic process cytoplasm, cytosol 4 iron, 4 sulfur cluster binding, NADP binding, dihydroorotate oxidase activity, dihydropyrimidine dehydrogenase (NADP+) activity, flavin adenine dinucleotide binding, iron-sulfur cluster binding, metal ion binding, oxidoreductase activity, protein homodimerization activity Human DPYS Reactome UniProtKB {GO:0051219=GO_REF:0000019, GO:0016810=GO_REF:0000002, GO:0006210=GO_REF:0000024, GO:0006212=PMID:10410956, GO:0055086=Reactome:REACT_1698, GO:0044281=Reactome:REACT_111217, GO:0002059=GO_REF:0000019, GO:0002058=GO_REF:0000019, GO:0005829=Reactome:REACT_2169, GO:0019482=GO_REF:0000019, GO:0046135=Reactome:REACT_1023, GO:0051289=GO_REF:0000024, GO:0008270=PMID:9718352, GO:0016597=GO_REF:0000019, GO:0004157=Reactome:REACT_2169, GO:0006206=Reactome:REACT_957, GO:0006208=PMID:9718352} Q14117 Dihydropyrimidinase protein 20130213 {GO:0051219=IEA, GO:0016810=IEA, GO:0006210=ISS, GO:0006212=IDA, GO:0055086=TAS, GO:0044281=TAS, GO:0002059=IEA, GO:0002058=IEA, GO:0005829=TAS, GO:0019482=IEA, GO:0046135=TAS, GO:0051289=ISS, GO:0008270=NAS, GO:0016597=IEA, GO:0004157=TAS, GO:0006206=TAS, GO:0006208=IDA} beta-alanine metabolic process, nucleobase-containing small molecule metabolic process, protein homotetramerization, pyrimidine nucleobase catabolic process, pyrimidine nucleobase metabolic process, pyrimidine nucleoside catabolic process, small molecule metabolic process, thymine catabolic process, uracil catabolic process cytosol amino acid binding, dihydropyrimidinase activity, hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, phosphoprotein binding, thymine binding, uracil binding, zinc ion binding Human DPYSL2 Reactome UniProtKB {GO:0005515=PMID:19235893, GO:0030424=GO_REF:0000019, GO:0021510=GO_REF:0000019, GO:0016810=GO_REF:0000002, GO:0042220=GO_REF:0000019, GO:0030425=GO_REF:0000019, GO:0030426=GO_REF:0000019, GO:0005829=Reactome:REACT_22358, GO:0014049=GO_REF:0000019, GO:0005739=GO_REF:0000019, GO:0021772=GO_REF:0000019, GO:0007411=Reactome:REACT_18266, GO:0007010=GO_REF:0000024, GO:0043025=GO_REF:0000019, GO:0019901=GO_REF:0000019, GO:0042493=GO_REF:0000019, GO:0048489=GO_REF:0000019, GO:0007399=PMID:8973361, GO:0043234=GO_REF:0000019, GO:0007165=PMID:8973361, GO:0001975=GO_REF:0000019, GO:0006139=PMID:8973361, GO:0045664=GO_REF:0000019, GO:0004157=PMID:8973361, GO:0006208=GO_REF:0000002} Q16555 Dihydropyrimidinase-related protein 2 protein 20091012 {GO:0005515=IPI, GO:0030424=IEA, GO:0021510=IEA, GO:0016810=IEA, GO:0042220=IEA, GO:0030425=IEA, GO:0030426=IEA, GO:0005829=TAS, GO:0014049=IEA, GO:0005739=IEA, GO:0021772=IEA, GO:0007411=TAS, GO:0007010=ISS, GO:0043025=IEA, GO:0019901=IEA, GO:0042493=IEA, GO:0048489=IEA, GO:0007399=TAS, GO:0043234=IEA, GO:0007165=TAS, GO:0001975=IEA, GO:0006139=TAS, GO:0045664=IEA, GO:0004157=TAS, GO:0006208=IEA} axon guidance, cytoskeleton organization, nervous system development, nucleobase-containing compound metabolic process, olfactory bulb development, positive regulation of glutamate secretion, pyrimidine nucleobase catabolic process, regulation of neuron differentiation, response to amphetamine, response to cocaine, response to drug, signal transduction, spinal cord development, synaptic vesicle transport axon, cytosol, dendrite, growth cone, mitochondrion, neuronal cell body, protein complex dihydropyrimidinase activity, hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, protein binding, protein kinase binding Human DPYSL3 Reactome UniProtKB {GO:0051219=GO_REF:0000019, GO:0017124=GO_REF:0000024, GO:0016810=GO_REF:0000002, GO:0016812=GO_REF:0000002, GO:0051491=GO_REF:0000024, GO:0005615=GO_REF:0000024, GO:0048678=GO_REF:0000024, GO:0035374=GO_REF:0000024, GO:0030426=GO_REF:0000024, GO:0005829=Reactome:REACT_19321, GO:0048666=GO_REF:0000019, GO:0007411=Reactome:REACT_18266, GO:0051260=GO_REF:0000024, GO:0051764=GO_REF:0000024, GO:0051017=GO_REF:0000024, GO:0030336=GO_REF:0000024, GO:0044297=GO_REF:0000024, GO:0030027=GO_REF:0000024, GO:0031941=GO_REF:0000024, GO:0016787=GO_REF:0000002, GO:0071345=GO_REF:0000024, GO:0010976=GO_REF:0000024, GO:0010977=GO_REF:0000024, GO:0070382=GO_REF:0000024, GO:0006208=GO_REF:0000002} Q14195 Dihydropyrimidinase-related protein 3 protein 20130301 {GO:0051219=IEA, GO:0017124=ISS, GO:0016810=IEA, GO:0016812=IEA, GO:0051491=ISS, GO:0005615=ISS, GO:0048678=ISS, GO:0035374=ISS, GO:0030426=ISS, GO:0005829=TAS, GO:0048666=IEA, GO:0007411=TAS, GO:0051260=ISS, GO:0051764=ISS, GO:0051017=ISS, GO:0030336=ISS, GO:0044297=ISS, GO:0030027=ISS, GO:0031941=ISS, GO:0016787=IEA, GO:0071345=ISS, GO:0010976=ISS, GO:0010977=ISS, GO:0070382=ISS, GO:0006208=IEA} actin crosslink formation, actin filament bundle assembly, axon guidance, cellular response to cytokine stimulus, negative regulation of cell migration, negative regulation of neuron projection development, neuron development, positive regulation of filopodium assembly, positive regulation of neuron projection development, protein homooligomerization, pyrimidine nucleobase catabolic process, response to axon injury cell body, cytosol, exocytic vesicle, extracellular space, filamentous actin, growth cone, lamellipodium SH3 domain binding, chondroitin sulfate binding, hydrolase activity, hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides, phosphoprotein binding Human DPYSL4 InterPro UniProtKB {GO:0016787=GO_REF:0000002, GO:0007411=Reactome:REACT_18266, GO:0016812=GO_REF:0000002, GO:0005829=Reactome:REACT_19321, GO:0007399=PMID:9652388, GO:0006208=GO_REF:0000002} Q5T0Q6 Dihydropyrimidinase-related protein 4 protein 20130413 {GO:0016787=IEA, GO:0007411=TAS, GO:0016812=IEA, GO:0005829=TAS, GO:0007399=TAS, GO:0006208=IEA} axon guidance, nervous system development, pyrimidine nucleobase catabolic process cytosol hydrolase activity, hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides Human InterPro:IPR006680 DPYSL5 Reactome UniProtKB {GO:0007165=PMID:10851247, GO:0043234=GO_REF:0000019, GO:0005737=GO_REF:0000019, GO:0016810=GO_REF:0000002, GO:0007411=Reactome:REACT_18266, GO:0016812=GO_REF:0000002, GO:0030182=GO_REF:0000019, GO:0043025=GO_REF:0000019, GO:0030425=GO_REF:0000019, GO:0005829=Reactome:REACT_19321, GO:0007399=PMID:10851247, GO:0006208=GO_REF:0000002} Q9BPU6 Dihydropyrimidinase-related protein 5 protein 20130301 {GO:0007165=TAS, GO:0043234=IEA, GO:0005737=IEA, GO:0016810=IEA, GO:0007411=TAS, GO:0016812=IEA, GO:0030182=IEA, GO:0043025=IEA, GO:0030425=IEA, GO:0005829=TAS, GO:0007399=TAS, GO:0006208=IEA} axon guidance, nervous system development, neuron differentiation, pyrimidine nucleobase catabolic process, signal transduction cytoplasm, cytosol, dendrite, neuronal cell body, protein complex hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides Human DQX1 UniProtKB UniProtKB {GO:0004386=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0003676=GO_REF:0000002, GO:0005524=GO_REF:0000037} Q8TE96 ATP-dependent RNA helicase DQX1 protein 20130413 {GO:0004386=IEA, GO:0005634=IEA, GO:0003676=IEA, GO:0005524=IEA} nucleus ATP binding, helicase activity, nucleic acid binding Human UniProtKB-SubCell:SL-0191 DR1 BHF-UCL UniProtKB {GO:0005515=PMID:18838386, GO:0043565=GO_REF:0000002, GO:0043966=PMID:18838386, GO:0046982=GO_REF:0000002, GO:0003714=PMID:8670811, GO:0017025=PMID:18838386, GO:0005671=PMID:18838386, GO:0000122=PMID:8670811, GO:0003677=PMID:8670811, GO:0006351=GO_REF:0000037, GO:0008134=PMID:1339312} Q01658 Protein Dr1 protein 20101105 {GO:0005515=IPI, GO:0043565=IEA, GO:0043966=IDA, GO:0046982=IEA, GO:0003714=TAS, GO:0017025=IDA, GO:0005671=IDA, GO:0000122=TAS, GO:0003677=TAS, GO:0006351=IEA, GO:0008134=TAS} histone H3 acetylation, negative regulation of transcription from RNA polymerase II promoter, transcription, DNA-dependent Ada2/Gcn5/Ada3 transcription activator complex DNA binding, TBP-class protein binding, protein binding, protein heterodimerization activity, sequence-specific DNA binding, transcription corepressor activity, transcription factor binding Human DRAM1 UniProtKB UniProtKB {GO:0006914=GO_REF:0000037, GO:0006915=GO_REF:0000037, GO:0016021=GO_REF:0000037, GO:0005765=GO_REF:0000039} Q8N682 DNA damage-regulated autophagy modulator protein 1 protein 20130413 {GO:0006914=IEA, GO:0006915=IEA, GO:0016021=IEA, GO:0005765=IEA} apoptotic process, autophagy integral to membrane, lysosomal membrane Human UniProtKB-SubCell:SL-0157 DRAM2 HPA UniProtKB {GO:0005794=GO_REF:0000052, GO:0006915=GO_REF:0000037, GO:0006917=PMID:19895784, GO:0016021=GO_REF:0000037, GO:0005765=GO_REF:0000039, GO:0005764=PMID:19556885, GO:0043231=GO_REF:0000052} Q6UX65 DNA damage-regulated autophagy modulator protein 2 protein 20090616 {GO:0005794=IDA, GO:0006915=IEA, GO:0006917=IDA, GO:0016021=IEA, GO:0005765=IEA, GO:0005764=IDA, GO:0043231=IDA} apoptotic process, induction of apoptosis Golgi apparatus, integral to membrane, intracellular membrane-bounded organelle, lysosomal membrane, lysosome Human DRAP1 PINC UniProtKB {GO:0043565=GO_REF:0000002, GO:0003700=PMID:8608938, GO:0046982=GO_REF:0000002, GO:0003714=GO_REF:0000019, GO:0005634=GO_REF:0000039, GO:0000122=GO_REF:0000019, GO:0003677=PMID:8670811, GO:0006351=GO_REF:0000037, GO:0008134=GO_REF:0000019} Q14919 Dr1-associated corepressor protein 20050308 {GO:0043565=IEA, GO:0003700=TAS, GO:0046982=IEA, GO:0003714=IEA, GO:0005634=IEA, GO:0000122=IEA, GO:0003677=TAS, GO:0006351=IEA, GO:0008134=IEA} negative regulation of transcription from RNA polymerase II promoter, transcription, DNA-dependent nucleus DNA binding, protein heterodimerization activity, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, transcription corepressor activity, transcription factor binding Human DRD1 BHF-UCL UniProtKB {GO:0005515=PMID:15569306, GO:0001659=GO_REF:0000019, GO:0043268=GO_REF:0000024, GO:0060291=GO_REF:0000019, GO:0060292=GO_REF:0000019, GO:0006606=GO_REF:0000019, GO:0019226=GO_REF:0000024, GO:0019228=GO_REF:0000019, GO:0051584=PMID:8301582, GO:0046323=GO_REF:0000019, GO:0051482=PMID:1282671, GO:0001662=GO_REF:0000019, GO:0007613=GO_REF:0000019, GO:0001661=GO_REF:0000019, GO:0021542=GO_REF:0000019, GO:0001588=PMID:2168520, GO:0030335=GO_REF:0000024, GO:0007617=GO_REF:0000024, GO:0060134=GO_REF:0000024, GO:0051968=GO_REF:0000024, GO:0035240=PMID:1282671, GO:0030432=GO_REF:0000019, GO:0007416=GO_REF:0000024, GO:0005887=PMID:2144334, GO:0007187=PMID:1282671, GO:0071870=PMID:18403039, GO:0008542=GO_REF:0000024, GO:0005789=GO_REF:0000039, GO:0097458=GO_REF:0000002, GO:0007189=PMID:2144334, GO:0005886=PMID:15569306, GO:0030819=PMID:7838121, GO:0048148=GO_REF:0000019, GO:0005634=GO_REF:0000019, GO:0042053=GO_REF:0000019, GO:0007191=PMID:18403039, GO:0007190=PMID:2168520, GO:0042417=PMID:8301582, GO:0042311=GO_REF:0000002, GO:0001963=GO_REF:0000019, GO:0007628=GO_REF:0000024, GO:0035106=GO_REF:0000019, GO:0007625=GO_REF:0000019, GO:0051281=PMID:7838121, GO:0015872=GO_REF:0000019, GO:0042493=GO_REF:0000024, GO:0004952=PMID:1831904, GO:0046960=GO_REF:0000019, GO:0010579=GO_REF:0000002, GO:0021853=GO_REF:0000024, GO:0021756=GO_REF:0000019, GO:0001975=GO_REF:0000019, GO:0014002=GO_REF:0000019, GO:0060158=PMID:1282671} P21728 D(1A) dopamine receptor protein 20120329 {GO:0005515=IPI, GO:0001659=IEA, GO:0043268=ISS, GO:0060291=IEA, GO:0060292=IEA, GO:0006606=IEA, GO:0019226=ISS, GO:0019228=IEA, GO:0051584=IC, GO:0046323=IEA, GO:0051482=IDA, GO:0001662=IEA, GO:0007613=IEA, GO:0001661=IEA, GO:0021542=IEA, GO:0001588=IDA, GO:0030335=ISS, GO:0007617=ISS, GO:0060134=ISS, GO:0051968=ISS, GO:0035240=IMP, GO:0030432=IEA, GO:0007416=ISS, GO:0005887=IC, GO:0007187=IDA, GO:0071870=IDA, GO:0008542=ISS, GO:0005789=IEA, GO:0097458=IEA, GO:0007189=IDA, GO:0005886=IDA, GO:0030819=IDA, GO:0048148=IEA, GO:0005634=IEA, GO:0042053=IEA, GO:0007191=IDA, GO:0007190=IDA, GO:0042417=IC, GO:0042311=IEA, GO:0001963=IEA, GO:0007628=ISS, GO:0035106=IEA, GO:0007625=IEA, GO:0051281=IDA, GO:0015872=IEA, GO:0042493=ISS, GO:0004952=IDA, GO:0046960=IEA, GO:0010579=IEA, GO:0021853=ISS, GO:0021756=IEA, GO:0001975=IEA, GO:0014002=IEA, GO:0060158=IDA} G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger, activation of adenylate cyclase activity, adenylate cyclase-activating G-protein coupled receptor signaling pathway, adenylate cyclase-activating dopamine receptor signaling pathway, adult walking behavior, astrocyte development, behavioral fear response, behavioral response to cocaine, cellular response to catecholamine stimulus, cerebral cortex GABAergic interneuron migration, conditioned taste aversion, dentate gyrus development, dopamine metabolic process, dopamine transport, elevation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway, glucose import, grooming behavior, long term synaptic depression, long-term synaptic potentiation, mating behavior, memory, operant conditioning, peristalsis, phospholipase C-activating dopamine receptor signaling pathway, positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway, positive regulation of cAMP biosynthetic process, positive regulation of cell migration, positive regulation of potassium ion transport, positive regulation of release of sequestered calcium ion into cytosol, positive regulation of synaptic transmission, glutamatergic, prepulse inhibition, protein import into nucleus, regulation of action potential in neuron, regulation of dopamine metabolic process, regulation of dopamine uptake involved in synaptic transmission, response to amphetamine, response to drug, sensitization, striatum development, synapse assembly, synaptic transmission, dopaminergic, temperature homeostasis, transmission of nerve impulse, vasodilation, visual learning endoplasmic reticulum membrane, integral to plasma membrane, neuron part, nucleus, plasma membrane dopamine binding, dopamine neurotransmitter receptor activity, dopamine neurotransmitter receptor activity, coupled via Gs, protein binding Human DRD2 ENSEMBL UniProtKB {GO:0005515=PMID:10692483, GO:0043266=GO_REF:0000019, GO:0030672=GO_REF:0000019, GO:0016055=GO_REF:0000019, GO:0046676=GO_REF:0000019, GO:0008306=GO_REF:0000024, GO:0045745=GO_REF:0000019, GO:0051209=GO_REF:0000019, GO:0051967=GO_REF:0000019, GO:0060134=GO_REF:0000019, GO:0046488=GO_REF:0000019, GO:0009636=GO_REF:0000019, GO:0035240=GO_REF:0000019, GO:0043278=GO_REF:0000019, GO:0007270=GO_REF:0000024, GO:0005887=GO_REF:0000002, GO:0035815=GO_REF:0000019, GO:0001591=GO_REF:0000019, GO:0035810=GO_REF:0000019, GO:0034776=PMID:16839358, GO:0021984=GO_REF:0000019, GO:0060124=GO_REF:0000019, GO:0007631=GO_REF:0000019, GO:0030424=GO_REF:0000024, GO:0048148=GO_REF:0000019, GO:0007195=GO_REF:0000019, GO:0007194=GO_REF:0000019, GO:0030425=GO_REF:0000024, GO:0046717=GO_REF:0000019, GO:0042417=GO_REF:0000019, GO:0008144=GO_REF:0000019, GO:0001963=GO_REF:0000019, GO:0007628=GO_REF:0000019, GO:0043204=GO_REF:0000019, GO:0007626=GO_REF:0000024, GO:0030815=GO_REF:0000002, GO:0007625=GO_REF:0000019, GO:0030814=PMID:8666994, GO:0040018=GO_REF:0000019, GO:0014854=GO_REF:0000019, GO:0050482=PMID:8301582, GO:0042493=GO_REF:0000019, GO:0004952=GO_REF:0000002, GO:0021853=GO_REF:0000019, GO:0001975=GO_REF:0000019, GO:0001976=GO_REF:0000019, GO:0042321=GO_REF:0000019, GO:0048149=GO_REF:0000019, GO:0048755=GO_REF:0000019, GO:0002092=GO_REF:0000019, GO:0035094=GO_REF:0000019, GO:0007608=GO_REF:0000019, GO:0001659=GO_REF:0000019, GO:0007409=GO_REF:0000019, GO:0042220=GO_REF:0000024, GO:0048678=GO_REF:0000019, GO:0042221=GO_REF:0000002, GO:0031223=GO_REF:0000019, GO:0051584=PMID:8301582, GO:0051586=GO_REF:0000019, GO:0010039=GO_REF:0000019, GO:0048169=GO_REF:0000019, GO:0009416=GO_REF:0000024, GO:0070374=GO_REF:0000019, GO:0030336=GO_REF:0000019, GO:0007616=GO_REF:0000019, GO:1901386=GO_REF:0000019, GO:0014069=GO_REF:0000019, GO:0007416=GO_REF:0000019, GO:0030432=GO_REF:0000019, GO:0002031=GO_REF:0000019, GO:0032922=GO_REF:0000019, GO:0002027=GO_REF:0000019, GO:0008542=GO_REF:0000019, GO:0032228=GO_REF:0000019, GO:0002028=GO_REF:0000019, GO:0050709=PMID:16839358, GO:0097458=GO_REF:0000002, GO:0051898=GO_REF:0000019, GO:0008285=GO_REF:0000019, GO:0005886=Reactome:REACT_22289, GO:0030139=GO_REF:0000019, GO:0045776=GO_REF:0000019, GO:0014059=GO_REF:0000019, GO:0032147=GO_REF:0000019, GO:0008104=GO_REF:0000019, GO:0045944=GO_REF:0000019, GO:0043679=GO_REF:0000019, GO:0001666=GO_REF:0000019, GO:0060160=GO_REF:0000019, GO:0001669=GO_REF:0000019, GO:0051481=GO_REF:0000019, GO:0002052=GO_REF:0000019, GO:0016328=GO_REF:0000019, GO:0035255=GO_REF:0000019, GO:0060158=GO_REF:0000019, GO:0043473=GO_REF:0000019, GO:0043666=GO_REF:0000019} Q6LDH7 D(2) dopamine receptor protein 20130413 {GO:0005515=IPI, GO:0043266=IEA, GO:0030672=IEA, GO:0016055=IEA, GO:0046676=IEA, GO:0008306=ISS, GO:0045745=IEA, GO:0051209=IEA, GO:0051967=IEA, GO:0060134=IEA, GO:0046488=IEA, GO:0009636=IEA, GO:0035240=IEA, GO:0043278=IEA, GO:0007270=ISS, GO:0005887=IEA, GO:0035815=IEA, GO:0001591=IEA, GO:0035810=IEA, GO:0034776=IDA, GO:0021984=IEA, GO:0060124=IEA, GO:0007631=IEA, GO:0030424=ISS, GO:0048148=IEA, GO:0007195=IEA, GO:0007194=IEA, GO:0030425=ISS, GO:0046717=IEA, GO:0042417=IEA, GO:0008144=IEA, GO:0001963=IEA, GO:0007628=IEA, GO:0043204=IEA, GO:0007626=ISS, GO:0030815=IEA, GO:0007625=IEA, GO:0030814=IDA, GO:0040018=IEA, GO:0014854=IEA, GO:0050482=IDA, GO:0042493=IEA, GO:0004952=IEA, GO:0021853=IEA, GO:0001975=IEA, GO:0001976=IEA, GO:0042321=IEA, GO:0048149=IEA, GO:0048755=IEA, GO:0002092=IEA, GO:0035094=IEA, GO:0007608=IEA, GO:0001659=IEA, GO:0007409=IEA, GO:0042220=ISS, GO:0048678=IEA, GO:0042221=IEA, GO:0031223=IEA, GO:0051584=IC, GO:0051586=IEA, GO:0010039=IEA, GO:0048169=IEA, GO:0009416=ISS, GO:0070374=IEA, GO:0030336=IEA, GO:0007616=IEA, GO:1901386=IEA, GO:0014069=IEA, GO:0007416=IEA, GO:0030432=IEA, GO:0002031=IEA, GO:0032922=IEA, GO:0002027=IEA, GO:0008542=IEA, GO:0032228=IEA, GO:0002028=IEA, GO:0050709=IDA, GO:0097458=IEA, GO:0051898=IEA, GO:0008285=IEA, GO:0005886=TAS, GO:0030139=IEA, GO:0045776=IEA, GO:0014059=IEA, GO:0032147=IEA, GO:0008104=IEA, GO:0045944=IEA, GO:0043679=IEA, GO:0001666=IEA, GO:0060160=IEA, GO:0001669=IEA, GO:0051481=IEA, GO:0002052=IEA, GO:0016328=IEA, GO:0035255=IEA, GO:0060158=IEA, GO:0043473=IEA, GO:0043666=IEA} G-protein coupled receptor internalization, Wnt receptor signaling pathway, acid secretion, activation of protein kinase activity, adenohypophysis development, adenylate cyclase-inhibiting dopamine receptor signaling pathway, adult walking behavior, arachidonic acid secretion, associative learning, auditory behavior, axonogenesis, behavioral response to cocaine, behavioral response to ethanol, branching morphogenesis of a nerve, cerebral cortex GABAergic interneuron migration, circadian regulation of gene expression, dopamine metabolic process, feeding behavior, grooming behavior, locomotory behavior, long-term memory, negative regulation of adenylate cyclase activity, negative regulation of blood pressure, negative regulation of cAMP metabolic process, negative regulation of cell migration, negative regulation of cell proliferation, negative regulation of circadian sleep/wake cycle, sleep, negative regulation of dopamine receptor signaling pathway, negative regulation of insulin secretion, negative regulation of protein kinase B signaling cascade, negative regulation of protein secretion, negative regulation of synaptic transmission, glutamatergic, negative regulation of voltage-gated calcium channel activity, neurological system process involved in regulation of systemic arterial blood pressure, neuron-neuron synaptic transmission, peristalsis, phosphatidylinositol metabolic process, phospholipase C-activating dopamine receptor signaling pathway, pigmentation, positive regulation of ERK1 and ERK2 cascade, positive regulation of G-protein coupled receptor protein signaling pathway, positive regulation of dopamine uptake involved in synaptic transmission, positive regulation of growth hormone secretion, positive regulation of multicellular organism growth, positive regulation of neuroblast proliferation, positive regulation of receptor internalization, positive regulation of renal sodium excretion, positive regulation of transcription from RNA polymerase II promoter, positive regulation of urine volume, prepulse inhibition, protein localization, reduction of cytosolic calcium ion concentration, regulation of cAMP metabolic process, regulation of dopamine secretion, regulation of dopamine uptake involved in synaptic transmission, regulation of heart rate, regulation of long-term neuronal synaptic plasticity, regulation of phosphoprotein phosphatase activity, regulation of potassium ion transport, regulation of sodium ion transport, regulation of synaptic transmission, GABAergic, release of sequestered calcium ion into cytosol, response to amphetamine, response to axon injury, response to chemical stimulus, response to cocaine, response to drug, response to histamine, response to hypoxia, response to inactivity, response to iron ion, response to light stimulus, response to morphine, response to nicotine, response to toxic substance, sensory perception of smell, synapse assembly, synaptic transmission, dopaminergic, temperature homeostasis, visual learning acrosomal vesicle, axon, axon terminus, dendrite, endocytic vesicle, integral to plasma membrane, lateral plasma membrane, neuron part, perikaryon, plasma membrane, postsynaptic density, synaptic vesicle membrane dopamine binding, dopamine neurotransmitter receptor activity, dopamine neurotransmitter receptor activity, coupled via Gi/Go, drug binding, ionotropic glutamate receptor binding, protein binding Human Ensembl:ENSRNOP00000043759 DRD3 BHF-UCL UniProtKB {GO:0005515=PMID:10692483, GO:0032416=GO_REF:0000019, GO:0042995=GO_REF:0000019, GO:0042220=PMID:10415668, GO:0042221=GO_REF:0000002, GO:0051584=PMID:8301582, GO:0002016=GO_REF:0000019, GO:0050883=GO_REF:0000024, GO:0007611=PMID:14681904, GO:0007612=PMID:15998189, GO:0060134=PMID:18325483, GO:0019904=GO_REF:0000019, GO:0035240=GO_REF:0000019, GO:0045840=GO_REF:0000024, GO:0043278=GO_REF:0000024, GO:0000122=GO_REF:0000019, GO:0002031=PMID:18424554, GO:0032922=GO_REF:0000024, GO:0019216=GO_REF:0000019, GO:0007186=PMID:7911712, GO:0005887=PMID:8413587, GO:0008542=GO_REF:0000024, GO:0035815=GO_REF:0000019, GO:0035176=PMID:12860355, GO:0001591=GO_REF:0000024, GO:0050709=PMID:16839358, GO:0034776=PMID:16839358, GO:0051898=GO_REF:0000024, GO:0008284=GO_REF:0000019, GO:0005886=PMID:18424554, GO:0045471=GO_REF:0000024, GO:0045187=GO_REF:0000019, GO:0048148=GO_REF:0000024, GO:0030139=GO_REF:0000019, GO:0045776=GO_REF:0000024, GO:0007195=PMID:18424554, GO:0007194=PMID:7907363, GO:0014059=GO_REF:0000024, GO:0046717=GO_REF:0000024, GO:0007191=PMID:18424554, GO:0040012=GO_REF:0000019, GO:0042417=PMID:8301582, GO:0045944=GO_REF:0000019, GO:0008144=PMID:8413587, GO:0040014=GO_REF:0000019, GO:0001963=GO_REF:0000019, GO:0030815=GO_REF:0000002, GO:0007626=GO_REF:0000024, GO:0030814=PMID:8666994, GO:0060161=GO_REF:0000024, GO:0050482=PMID:8301582, GO:0060160=GO_REF:0000019, GO:0042493=GO_REF:0000024, GO:0006874=PMID:7911712, GO:0004952=GO_REF:0000002, GO:0045177=GO_REF:0000019, GO:0001975=GO_REF:0000019, GO:0048715=GO_REF:0000024} P35462 D(3) dopamine receptor protein 20080903 {GO:0005515=IPI, GO:0032416=IEA, GO:0042995=IEA, GO:0042220=IEP, GO:0042221=IEA, GO:0051584=IC, GO:0002016=IEA, GO:0050883=ISS, GO:0007611=NAS, GO:0007612=NAS, GO:0060134=IMP, GO:0019904=IEA, GO:0035240=IEA, GO:0045840=ISS, GO:0043278=ISS, GO:0000122=IEA, GO:0002031=IDA, GO:0032922=ISS, GO:0019216=IEA, GO:0007186=IDA, GO:0005887=IDA, GO:0008542=ISS, GO:0035815=IEA, GO:0035176=NAS, GO:0001591=ISS, GO:0050709=IDA, GO:0034776=IDA, GO:0051898=ISS, GO:0008284=IEA, GO:0005886=IDA, GO:0045471=ISS, GO:0045187=IEA, GO:0048148=ISS, GO:0030139=IEA, GO:0045776=ISS, GO:0007195=IDA, GO:0007194=IDA, GO:0014059=ISS, GO:0046717=ISS, GO:0007191=IDA, GO:0040012=IEA, GO:0042417=IC, GO:0045944=IEA, GO:0008144=IDA, GO:0040014=IEA, GO:0001963=IEA, GO:0030815=IEA, GO:0007626=ISS, GO:0030814=IDA, GO:0060161=ISS, GO:0050482=IDA, GO:0060160=IEA, GO:0042493=ISS, GO:0006874=IDA, GO:0004952=IEA, GO:0045177=IEA, GO:0001975=IEA, GO:0048715=ISS} G-protein coupled receptor internalization, G-protein coupled receptor signaling pathway, acid secretion, adenylate cyclase-activating dopamine receptor signaling pathway, adenylate cyclase-inhibiting dopamine receptor signaling pathway, arachidonic acid secretion, behavioral response to cocaine, cellular calcium ion homeostasis, circadian regulation of gene expression, dopamine metabolic process, learning, learning or memory, locomotory behavior, musculoskeletal movement, spinal reflex action, negative regulation of adenylate cyclase activity, negative regulation of blood pressure, negative regulation of cAMP metabolic process, negative regulation of dopamine receptor signaling pathway, negative regulation of oligodendrocyte differentiation, negative regulation of protein kinase B signaling cascade, negative regulation of protein secretion, negative regulation of sodium:hydrogen antiporter activity, negative regulation of transcription from RNA polymerase II promoter, positive regulation of cell proliferation, positive regulation of dopamine receptor signaling pathway, positive regulation of mitosis, positive regulation of renal sodium excretion, positive regulation of transcription from RNA polymerase II promoter, prepulse inhibition, regulation of blood volume by renin-angiotensin, regulation of cAMP metabolic process, regulation of circadian sleep/wake cycle, sleep, regulation of dopamine secretion, regulation of dopamine uptake involved in synaptic transmission, regulation of lipid metabolic process, regulation of locomotion, regulation of multicellular organism growth, response to amphetamine, response to chemical stimulus, response to cocaine, response to drug, response to ethanol, response to histamine, response to morphine, social behavior, synaptic transmission, dopaminergic, visual learning apical part of cell, cell projection, endocytic vesicle, integral to plasma membrane, plasma membrane dopamine binding, dopamine neurotransmitter receptor activity, dopamine neurotransmitter receptor activity, coupled via Gi/Go, drug binding, protein binding, protein domain specific binding Human UniProtKB:P19020 DRD4 BHF-UCL UniProtKB {GO:0005515=PMID:12297500, GO:0008344=GO_REF:0000024, GO:0017124=PMID:9843378, GO:0032417=PMID:7512953, GO:0005886=Reactome:REACT_22289, GO:0030818=PMID:7512953, GO:0048148=GO_REF:0000024, GO:0015459=PMID:12297500, GO:0007195=PMID:7512953, GO:0007194=PMID:7512953, GO:0042053=GO_REF:0000024, GO:0042596=GO_REF:0000024, GO:0000187=PMID:15755724, GO:0042417=PMID:1840645, GO:0043197=GO_REF:0000019, GO:0051586=PMID:1840645, GO:0008144=PMID:8413587, GO:0043195=GO_REF:0000019, GO:0001963=GO_REF:0000019, GO:0043025=GO_REF:0000019, GO:0001662=PMID:12860355, GO:0005938=GO_REF:0000019, GO:0050482=PMID:7512953, GO:0050848=GO_REF:0000019, GO:0012506=GO_REF:0000019, GO:0033674=PMID:15755724, GO:0008355=GO_REF:0000019, GO:0007614=GO_REF:0000019, GO:0004952=PMID:8413587, GO:0006874=PMID:7921596, GO:0046928=GO_REF:0000019, GO:1901386=PMID:7921596, GO:0035240=PMID:1319557, GO:0007212=PMID:1840645, GO:0001975=GO_REF:0000024, GO:0060080=GO_REF:0000024, GO:0016020=PMID:7512953, GO:0005887=PMID:15755724, GO:0048149=PMID:12888781, GO:0035176=PMID:11409696, GO:0050709=PMID:16839358, GO:0001591=GO_REF:0000024, GO:0034776=PMID:16839358} P21917 D(4) dopamine receptor protein 20080903 {GO:0005515=IPI, GO:0008344=ISS, GO:0017124=IDA, GO:0032417=IDA, GO:0005886=TAS, GO:0030818=IDA, GO:0048148=ISS, GO:0015459=NAS, GO:0007195=IDA, GO:0007194=IDA, GO:0042053=ISS, GO:0042596=ISS, GO:0000187=IDA, GO:0042417=IC, GO:0043197=IEA, GO:0051586=IC, GO:0008144=IDA, GO:0043195=IEA, GO:0001963=IEA, GO:0043025=IEA, GO:0001662=NAS, GO:0005938=IEA, GO:0050482=IDA, GO:0050848=IEA, GO:0012506=IEA, GO:0033674=IDA, GO:0008355=IEA, GO:0007614=IEA, GO:0004952=IDA, GO:0006874=IC, GO:0046928=IEA, GO:1901386=IDA, GO:0035240=IDA, GO:0007212=IDA, GO:0001975=ISS, GO:0060080=ISS, GO:0016020=IDA, GO:0005887=IDA, GO:0048149=TAS, GO:0035176=NAS, GO:0050709=IDA, GO:0001591=ISS, GO:0034776=IDA} activation of MAPK activity, adenylate cyclase-inhibiting dopamine receptor signaling pathway, adult locomotory behavior, arachidonic acid secretion, behavioral fear response, behavioral response to cocaine, behavioral response to ethanol, cellular calcium ion homeostasis, dopamine metabolic process, dopamine receptor signaling pathway, fear response, negative regulation of adenylate cyclase activity, negative regulation of cAMP biosynthetic process, negative regulation of protein secretion, negative regulation of voltage-gated calcium channel activity, olfactory learning, positive regulation of dopamine uptake involved in synaptic transmission, positive regulation of kinase activity, positive regulation of sodium:hydrogen antiporter activity, regulation of calcium-mediated signaling, regulation of dopamine metabolic process, regulation of inhibitory postsynaptic membrane potential, regulation of neurotransmitter secretion, response to amphetamine, response to histamine, short-term memory, social behavior, synaptic transmission, dopaminergic cell cortex, dendritic spine, integral to plasma membrane, membrane, neuronal cell body, plasma membrane, terminal bouton, vesicle membrane SH3 domain binding, dopamine binding, dopamine neurotransmitter receptor activity, dopamine neurotransmitter receptor activity, coupled via Gi/Go, drug binding, potassium channel regulator activity, protein binding Human DRD5 BHF-UCL UniProtKB {GO:0005886=Reactome:REACT_22268, GO:0007268=PMID:7727453, GO:0060292=GO_REF:0000019, GO:0045776=GO_REF:0000019, GO:0031526=GO_REF:0000019, GO:0042220=GO_REF:0000019, GO:0001992=GO_REF:0000019, GO:0007191=PMID:18403039, GO:0007190=PMID:9457173, GO:0001963=PMID:11036203, GO:0033861=PMID:16352863, GO:0045924=GO_REF:0000019, GO:0008306=GO_REF:0000019, GO:0001588=PMID:9457173, GO:0072593=PMID:16352863, GO:0004952=PMID:1826762, GO:0006874=PMID:9457173, GO:0046960=GO_REF:0000019, GO:0010579=GO_REF:0000002, GO:0035240=PMID:1826762, GO:0045762=PMID:1826762, GO:0001975=GO_REF:0000019, GO:0001994=GO_REF:0000019, GO:0005887=PMID:9457173, GO:0071870=PMID:18403039, GO:0042060=GO_REF:0000019, GO:0060158=PMID:9457173, GO:0007189=PMID:11500503} P21918 D(1B) dopamine receptor protein 20120329 {GO:0005886=TAS, GO:0007268=NAS, GO:0060292=IEA, GO:0045776=IEA, GO:0031526=IEA, GO:0042220=IEA, GO:0001992=IEA, GO:0007191=IDA, GO:0007190=TAS, GO:0001963=NAS, GO:0033861=IDA, GO:0045924=IEA, GO:0008306=IEA, GO:0001588=TAS, GO:0072593=IDA, GO:0004952=IDA, GO:0006874=TAS, GO:0046960=IEA, GO:0010579=IEA, GO:0035240=IDA, GO:0045762=IDA, GO:0001975=IEA, GO:0001994=IEA, GO:0005887=TAS, GO:0071870=IDA, GO:0042060=IEA, GO:0060158=TAS, GO:0007189=IDA} activation of adenylate cyclase activity, adenylate cyclase-activating G-protein coupled receptor signaling pathway, adenylate cyclase-activating dopamine receptor signaling pathway, associative learning, cellular calcium ion homeostasis, cellular response to catecholamine stimulus, long term synaptic depression, negative regulation of NAD(P)H oxidase activity, negative regulation of blood pressure, norepinephrine-epinephrine vasoconstriction involved in regulation of systemic arterial blood pressure, phospholipase C-activating dopamine receptor signaling pathway, positive regulation of adenylate cyclase activity, positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway, reactive oxygen species metabolic process, regulation of female receptivity, regulation of systemic arterial blood pressure by vasopressin, response to amphetamine, response to cocaine, sensitization, synaptic transmission, synaptic transmission, dopaminergic, wound healing brush border membrane, integral to plasma membrane, plasma membrane dopamine binding, dopamine neurotransmitter receptor activity, dopamine neurotransmitter receptor activity, coupled via Gs Human DRG1 HPA UniProtKB {GO:0005515=PMID:16189514, GO:0005737=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0007275=PMID:1280421, GO:0045111=GO_REF:0000052, GO:0005525=GO_REF:0000037, GO:0005844=PMID:19819225, GO:0006351=PMID:9824680, GO:0008134=PMID:9824680} Q9Y295 Developmentally-regulated GTP-binding protein 1 protein 20080818 {GO:0005515=IPI, GO:0005737=IDA, GO:0005634=IDA, GO:0007275=TAS, GO:0045111=IDA, GO:0005525=IEA, GO:0005844=IDA, GO:0006351=TAS, GO:0008134=TAS} multicellular organismal development, transcription, DNA-dependent cytoplasm, intermediate filament cytoskeleton, nucleus, polysome GTP binding, protein binding, transcription factor binding Human DRG2 HPA UniProtKB {GO:0005739=GO_REF:0000019, GO:0007165=PMID:7929244, GO:0005737=GO_REF:0000052, GO:0005525=GO_REF:0000037} P55039 Developmentally-regulated GTP-binding protein 2 protein 20080818 {GO:0005739=IEA, GO:0007165=TAS, GO:0005737=IDA, GO:0005525=IEA} signal transduction cytoplasm, mitochondrion GTP binding Human DROSHA IntAct UniProtKB {GO:0005515=PMID:15574589, GO:0003725=GO_REF:0000002, GO:0010467=Reactome:REACT_71, GO:0016075=GO_REF:0000002, GO:0004525=GO_REF:0000003, GO:0042254=GO_REF:0000037, GO:0031054=GO_REF:0000019, GO:0003723=GO_REF:0000002, GO:0005730=GO_REF:0000039, GO:0005654=Reactome:REACT_12414, GO:0046872=GO_REF:0000037, GO:0010586=GO_REF:0000019} Q9NRR4 Ribonuclease 3 protein 20130415 {GO:0005515=IPI, GO:0003725=IEA, GO:0010467=TAS, GO:0016075=IEA, GO:0004525=IEA, GO:0042254=IEA, GO:0031054=IEA, GO:0003723=IEA, GO:0005730=IEA, GO:0005654=TAS, GO:0046872=IEA, GO:0010586=IEA} gene expression, miRNA metabolic process, pre-miRNA processing, rRNA catabolic process, ribosome biogenesis nucleolus, nucleoplasm RNA binding, double-stranded RNA binding, metal ion binding, protein binding, ribonuclease III activity Human UniProtKB:Q8WYQ5 DRP2 PINC UniProtKB {GO:0005737=GO_REF:0000037, GO:0005886=GO_REF:0000019, GO:0005509=GO_REF:0000002, GO:0008270=GO_REF:0000002, GO:0007417=PMID:8640231, GO:0005856=GO_REF:0000039} Q13474 Dystrophin-related protein 2 protein 20030904 {GO:0005737=IEA, GO:0005886=IEA, GO:0005509=IEA, GO:0008270=IEA, GO:0007417=TAS, GO:0005856=IEA} central nervous system development cytoplasm, cytoskeleton, plasma membrane calcium ion binding, zinc ion binding Human DSC1 PINC UniProtKB {GO:0030057=GO_REF:0000039, GO:0016020=PMID:7679953, GO:0005886=GO_REF:0000039, GO:0005509=GO_REF:0000002, GO:0005921=PMID:7679953, GO:0016021=GO_REF:0000037, GO:0007156=GO_REF:0000002} Q08554 Desmocollin-1 protein 20030904 {GO:0030057=IEA, GO:0016020=TAS, GO:0005886=IEA, GO:0005509=IEA, GO:0005921=TAS, GO:0016021=IEA, GO:0007156=IEA} homophilic cell adhesion desmosome, gap junction, integral to membrane, membrane, plasma membrane calcium ion binding Human DSC2 BHF-UCL UniProtKB {GO:0030057=PMID:21062920, GO:0086069=PMID:22781308, GO:0005913=GO_REF:0000019, GO:0005886=GO_REF:0000039, GO:0005509=GO_REF:0000002, GO:0016021=GO_REF:0000037, GO:0086091=PMID:22781308, GO:0007155=PMID:2037591, GO:0007156=GO_REF:0000002, GO:0086005=PMID:22781308} Q02487 Desmocollin-2 protein 20120928 {GO:0030057=IDA, GO:0086069=IMP, GO:0005913=IEA, GO:0005886=IEA, GO:0005509=IEA, GO:0016021=IEA, GO:0086091=IMP, GO:0007155=TAS, GO:0007156=IEA, GO:0086005=IMP} bundle of His cell to Purkinje myocyte communication, cell adhesion, homophilic cell adhesion, regulation of heart rate by cardiac conduction, regulation of ventricular cardiac muscle cell action potential cell-cell adherens junction, desmosome, integral to membrane, plasma membrane calcium ion binding Human DSC3 PINC UniProtKB {GO:0030057=GO_REF:0000039, GO:0005737=GO_REF:0000019, GO:0005886=GO_REF:0000039, GO:0016020=PMID:7929347, GO:0005911=PMID:7929347, GO:0005509=GO_REF:0000002, GO:0005576=GO_REF:0000019, GO:0016021=GO_REF:0000037, GO:0007155=PMID:7929347, GO:0001701=GO_REF:0000019, GO:0007156=GO_REF:0000002} Q14574 Desmocollin-3 protein 20030904 {GO:0030057=IEA, GO:0005737=IEA, GO:0005886=IEA, GO:0016020=TAS, GO:0005911=TAS, GO:0005509=IEA, GO:0005576=IEA, GO:0016021=IEA, GO:0007155=TAS, GO:0001701=IEA, GO:0007156=IEA} cell adhesion, homophilic cell adhesion, in utero embryonic development cell-cell junction, cytoplasm, desmosome, extracellular region, integral to membrane, membrane, plasma membrane calcium ion binding Human DSCAM Reactome UniProtKB {GO:0005515=PMID:19196994, GO:0030424=GO_REF:0000024, GO:0005886=Reactome:REACT_25384, GO:0048842=PMID:18585357, GO:0005576=GO_REF:0000039, GO:0007399=PMID:9426258, GO:0070593=GO_REF:0000024, GO:0030426=GO_REF:0000024, GO:0048813=GO_REF:0000019, GO:0007162=GO_REF:0000024, GO:0016020=PMID:9426258, GO:0005887=PMID:9426258, GO:0007626=GO_REF:0000019, GO:0007155=GO_REF:0000037, GO:0060060=GO_REF:0000019, GO:0042327=PMID:19196994} O60469 Down syndrome cell adhesion molecule protein 20100105 {GO:0005515=IPI, GO:0030424=ISS, GO:0005886=TAS, GO:0048842=IDA, GO:0005576=IEA, GO:0007399=TAS, GO:0070593=ISS, GO:0030426=ISS, GO:0048813=IEA, GO:0007162=ISS, GO:0016020=TAS, GO:0005887=TAS, GO:0007626=IEA, GO:0007155=IEA, GO:0060060=IEA, GO:0042327=IDA} cell adhesion, dendrite morphogenesis, dendrite self-avoidance, locomotory behavior, negative regulation of cell adhesion, nervous system development, positive regulation of axon extension involved in axon guidance, positive regulation of phosphorylation, post-embryonic retina morphogenesis in camera-type eye axon, extracellular region, growth cone, integral to plasma membrane, membrane, plasma membrane protein binding Human DSCAML1 Reactome UniProtKB {GO:0009986=PMID:11453658, GO:0005886=Reactome:REACT_25036, GO:0001709=PMID:12051741, GO:0048704=PMID:12051741, GO:0007409=PMID:11453658, GO:0009953=PMID:12051741, GO:0007417=PMID:12051741, GO:0042803=PMID:11453658, GO:0070593=GO_REF:0000019, GO:0007162=GO_REF:0000019, GO:0007420=PMID:12051741, GO:0016021=GO_REF:0000037, GO:0007156=PMID:11453658} Q8TD84 Down syndrome cell adhesion molecule-like protein 1 protein 20100105 {GO:0009986=IDA, GO:0005886=TAS, GO:0001709=NAS, GO:0048704=IDA, GO:0007409=NAS, GO:0009953=NAS, GO:0007417=NAS, GO:0042803=IDA, GO:0070593=IEA, GO:0007162=IEA, GO:0007420=IDA, GO:0016021=IEA, GO:0007156=IDA} axonogenesis, brain development, cell fate determination, central nervous system development, dendrite self-avoidance, dorsal/ventral pattern formation, embryonic skeletal system morphogenesis, homophilic cell adhesion, negative regulation of cell adhesion cell surface, integral to membrane, plasma membrane protein homodimerization activity Human DSCC1 UniProtKB UniProtKB {GO:0005515=PMID:16682347, GO:0006260=GO_REF:0000037, GO:0034421=PMID:19907496, GO:0034088=PMID:19907496, GO:0005654=PMID:16682347, GO:0000785=PMID:19907496, GO:0003677=GO_REF:0000037, GO:0006275=PMID:19907496, GO:0000775=PMID:16682347} Q9BVC3 Sister chromatid cohesion protein DCC1 protein 20100924 {GO:0005515=IPI, GO:0006260=IEA, GO:0034421=IMP, GO:0034088=IMP, GO:0005654=IDA, GO:0000785=IDA, GO:0003677=IEA, GO:0006275=IMP, GO:0000775=IDA} DNA replication, maintenance of mitotic sister chromatid cohesion, post-translational protein acetylation, regulation of DNA replication chromatin, chromosome, centromeric region, nucleoplasm DNA binding, protein binding Human DSCR3 UniProtKB UniProtKB {GO:0003674=GO_REF:0000015, GO:0008150=GO_REF:0000015, GO:0007034=GO_REF:0000002, GO:0005634=PMID:16780588, GO:0030904=GO_REF:0000002} O14972 Down syndrome critical region protein 3 protein 20070711 {GO:0003674=ND, GO:0008150=ND, GO:0007034=IEA, GO:0005634=IDA, GO:0030904=IEA} biological_process, vacuolar transport nucleus, retromer complex molecular_function Human DSE Reactome UniProtKB {GO:0030208=Reactome:REACT_120800, GO:0030206=GO_REF:0000041, GO:0005794=PMID:10679095, GO:0000139=Reactome:REACT_120814, GO:0005975=Reactome:REACT_474, GO:0005783=PMID:10679095, GO:0047757=PMID:16505484, GO:0044281=Reactome:REACT_111217, GO:0015012=GO_REF:0000041, GO:0016021=GO_REF:0000037, GO:0030204=Reactome:REACT_121206, GO:0030203=Reactome:REACT_121315} Q9UL01 Dermatan-sulfate epimerase protein 20130301 {GO:0030208=TAS, GO:0030206=IEA, GO:0005794=IDA, GO:0000139=TAS, GO:0005975=TAS, GO:0005783=IDA, GO:0047757=IDA, GO:0044281=TAS, GO:0015012=IEA, GO:0016021=IEA, GO:0030204=TAS, GO:0030203=TAS} carbohydrate metabolic process, chondroitin sulfate biosynthetic process, chondroitin sulfate metabolic process, dermatan sulfate biosynthetic process, glycosaminoglycan metabolic process, heparan sulfate proteoglycan biosynthetic process, small molecule metabolic process Golgi apparatus, Golgi membrane, endoplasmic reticulum, integral to membrane chondroitin-glucuronate 5-epimerase activity Human DSEL UniProtKB UniProtKB {GO:0008146=GO_REF:0000002, GO:0016021=GO_REF:0000037, GO:0016853=GO_REF:0000037} Q8IZU8 Dermatan-sulfate epimerase-like protein protein 20130413 {GO:0008146=IEA, GO:0016021=IEA, GO:0016853=IEA} integral to membrane isomerase activity, sulfotransferase activity Human UniProtKB-KW:KW-0413 DSG1 BHF-UCL UniProtKB {GO:0030057=PMID:1711210, GO:0045295=PMID:7983064, GO:0005886=Reactome:REACT_11997, GO:0005509=PMID:1770008, GO:0060135=GO_REF:0000019, GO:0050821=PMID:7983064, GO:0006915=Reactome:REACT_578, GO:0016328=GO_REF:0000019, GO:0006921=Reactome:REACT_995, GO:0005829=Reactome:REACT_11997, GO:0016339=PMID:1770008, GO:0016324=GO_REF:0000019, GO:0016337=PMID:1711210, GO:0005911=PMID:7983064, GO:0015643=PMID:12582396, GO:0032570=GO_REF:0000019, GO:0007043=PMID:12485422, GO:0009898=PMID:7983064, GO:0016021=GO_REF:0000037, GO:0007156=GO_REF:0000002} Q02413 Desmoglein-1 protein 20100203 {GO:0030057=NAS, GO:0045295=IPI, GO:0005886=TAS, GO:0005509=NAS, GO:0060135=IEA, GO:0050821=IDA, GO:0006915=TAS, GO:0016328=IEA, GO:0006921=TAS, GO:0005829=TAS, GO:0016339=NAS, GO:0016324=IEA, GO:0016337=NAS, GO:0005911=IDA, GO:0015643=NAS, GO:0032570=IEA, GO:0007043=NAS, GO:0009898=IDA, GO:0016021=IEA, GO:0007156=IEA} apoptotic process, calcium-dependent cell-cell adhesion, cell-cell adhesion, cell-cell junction assembly, cellular component disassembly involved in execution phase of apoptosis, homophilic cell adhesion, maternal process involved in female pregnancy, protein stabilization, response to progesterone stimulus apical plasma membrane, cell-cell junction, cytosol, desmosome, integral to membrane, internal side of plasma membrane, lateral plasma membrane, plasma membrane calcium ion binding, gamma-catenin binding, toxic substance binding Human DSG2 BHF-UCL UniProtKB {GO:0030057=GO_REF:0000039, GO:0005886=GO_REF:0000052, GO:0005509=GO_REF:0000002, GO:0097194=PMID:17559062, GO:0006915=Reactome:REACT_578, GO:0086091=PMID:22781308, GO:0006921=Reactome:REACT_995, GO:0086069=PMID:22781308, GO:0005911=PMID:8143788, GO:0016021=GO_REF:0000037, GO:0007155=PMID:17559062, GO:0007156=GO_REF:0000002, GO:0086005=PMID:22781308} Q14126 Desmoglein-2 protein 20120928 {GO:0030057=IEA, GO:0005886=IDA, GO:0005509=IEA, GO:0097194=IDA, GO:0006915=TAS, GO:0086091=IMP, GO:0006921=TAS, GO:0086069=IMP, GO:0005911=TAS, GO:0016021=IEA, GO:0007155=IDA, GO:0007156=IEA, GO:0086005=IMP} apoptotic process, bundle of His cell to Purkinje myocyte communication, cell adhesion, cellular component disassembly involved in execution phase of apoptosis, execution phase of apoptosis, homophilic cell adhesion, regulation of heart rate by cardiac conduction, regulation of ventricular cardiac muscle cell action potential cell-cell junction, desmosome, integral to membrane, plasma membrane calcium ion binding Human DSG3 Reactome UniProtKB {GO:0030057=GO_REF:0000039, GO:0005886=Reactome:REACT_12082, GO:0005509=GO_REF:0000002, GO:0006915=Reactome:REACT_578, GO:0016021=GO_REF:0000037, GO:0007156=GO_REF:0000002, GO:0006921=Reactome:REACT_995, GO:0005829=Reactome:REACT_12082} P32926 Desmoglein-3 protein 20130301 {GO:0030057=IEA, GO:0005886=TAS, GO:0005509=IEA, GO:0006915=TAS, GO:0016021=IEA, GO:0007156=IEA, GO:0006921=TAS, GO:0005829=TAS} apoptotic process, cellular component disassembly involved in execution phase of apoptosis, homophilic cell adhesion cytosol, desmosome, integral to membrane, plasma membrane calcium ion binding Human DSN1 HPA UniProtKB {GO:0005515=PMID:15502821, GO:0000236=Reactome:REACT_682, GO:0005737=GO_REF:0000052, GO:0007059=GO_REF:0000037, GO:0000087=Reactome:REACT_910, GO:0005634=GO_REF:0000052, GO:0000444=PMID:16585270, GO:0000278=Reactome:REACT_152, GO:0000090=Reactome:REACT_1275, GO:0005829=Reactome:REACT_150414, GO:0051301=GO_REF:0000037} Q9H410 Kinetochore-associated protein DSN1 homolog protein 20080205 {GO:0005515=IPI, GO:0000236=TAS, GO:0005737=IDA, GO:0007059=IEA, GO:0000087=TAS, GO:0005634=IDA, GO:0000444=IDA, GO:0000278=TAS, GO:0000090=TAS, GO:0005829=TAS, GO:0051301=IEA} M phase of mitotic cell cycle, cell division, chromosome segregation, mitotic anaphase, mitotic cell cycle, mitotic prometaphase MIS12/MIND type complex, cytoplasm, cytosol, nucleus protein binding Human DSP BHF-UCL UniProtKB {GO:0005882=PMID:16917092, GO:0005515=PMID:16917092, GO:0030057=GO_REF:0000039, GO:0045109=PMID:16917092, GO:0005886=PMID:16917092, GO:0086091=PMID:22781308, GO:0001533=PMID:10908733, GO:0006921=Reactome:REACT_995, GO:0005739=GO_REF:0000019, GO:0016323=GO_REF:0000019, GO:0016337=GO_REF:0000019, GO:0086069=PMID:22781308, GO:0003223=PMID:16917092, GO:0097110=PMID:10852826, GO:0005080=PMID:18474624, GO:0030674=PMID:10908733, GO:0086005=PMID:22781308, GO:0006915=Reactome:REACT_578, GO:0018149=PMID:10908733, GO:0002934=PMID:16917092, GO:0008544=PMID:9887343, GO:0030216=PMID:10908733, GO:0005198=PMID:10908733, GO:0071896=PMID:16917092, GO:0005200=PMID:9887343, GO:0043588=GO_REF:0000019, GO:0034332=GO_REF:0000019} P15924 Desmoplakin protein 20120625 {GO:0005882=ISS, GO:0005515=IPI, GO:0030057=IEA, GO:0045109=ISS, GO:0005886=IDA, GO:0086091=IMP, GO:0001533=IDA, GO:0006921=TAS, GO:0005739=IEA, GO:0016323=IEA, GO:0016337=IEA, GO:0086069=IMP, GO:0003223=ISS, GO:0097110=IPI, GO:0005080=IPI, GO:0030674=IDA, GO:0086005=IMP, GO:0006915=TAS, GO:0018149=IDA, GO:0002934=ISS, GO:0008544=TAS, GO:0030216=IDA, GO:0005198=IDA, GO:0071896=ISS, GO:0005200=TAS, GO:0043588=IEA, GO:0034332=IEA} adherens junction organization, apoptotic process, bundle of His cell to Purkinje myocyte communication, cell-cell adhesion, cellular component disassembly involved in execution phase of apoptosis, desmosome organization, epidermis development, intermediate filament organization, keratinocyte differentiation, peptide cross-linking, protein localization to adherens junction, regulation of heart rate by cardiac conduction, regulation of ventricular cardiac muscle cell action potential, skin development, ventricular compact myocardium morphogenesis basolateral plasma membrane, cornified envelope, desmosome, intermediate filament, mitochondrion, plasma membrane protein binding, protein binding, bridging, protein kinase C binding, scaffold protein binding, structural constituent of cytoskeleton, structural molecule activity colocalizes_with Human UniProtKB:E9Q557 DSPP PINC UniProtKB {GO:0001501=PMID:8995371, GO:0001503=PMID:9879917, GO:0071460=GO_REF:0000019, GO:0005518=PMID:9879917, GO:0005509=PMID:9879917, GO:0005578=GO_REF:0000039, GO:0007275=PMID:8995371, GO:0031214=GO_REF:0000037, GO:0005201=PMID:8995371} Q9NZW4 Dentin sialophosphoprotein protein 20050308 {GO:0001501=TAS, GO:0001503=TAS, GO:0071460=IEA, GO:0005518=TAS, GO:0005509=TAS, GO:0005578=IEA, GO:0007275=TAS, GO:0031214=IEA, GO:0005201=TAS} biomineral tissue development, cellular response to cell-matrix adhesion, multicellular organismal development, ossification, skeletal system development proteinaceous extracellular matrix calcium ion binding, collagen binding, extracellular matrix structural constituent Human DST UniProtKB UniProtKB {GO:0005515=PMID:19632184, GO:0005882=GO_REF:0000037, GO:0030424=GO_REF:0000039, GO:0030056=PMID:11375975, GO:0008090=GO_REF:0000019, GO:0030018=GO_REF:0000039, GO:0045104=PMID:11375975, GO:0042626=GO_REF:0000002, GO:0035371=PMID:19632184, GO:0005634=GO_REF:0000052, GO:0031122=GO_REF:0000019, GO:0030011=PMID:19403692, GO:0007409=GO_REF:0000019, GO:0005635=GO_REF:0000039, GO:0015629=GO_REF:0000019, GO:0005829=Reactome:REACT_150217, GO:0005737=GO_REF:0000052, GO:0009925=PMID:11375975, GO:0051010=PMID:19632184, GO:0030198=Reactome:REACT_118779, GO:0048870=PMID:19403692, GO:0007010=PMID:19403692, GO:0015630=GO_REF:0000052, GO:0007050=GO_REF:0000002, GO:0007155=GO_REF:0000037, GO:0005856=GO_REF:0000002, GO:0031252=PMID:19403692, GO:0005938=GO_REF:0000039, GO:0060053=GO_REF:0000019, GO:0031110=GO_REF:0000019, GO:0005509=GO_REF:0000002, GO:0009611=PMID:19403692, GO:0003779=GO_REF:0000038, GO:0008022=PMID:11375975, GO:0005524=GO_REF:0000002, GO:0005604=PMID:2461961, GO:0005178=PMID:11375975, GO:0007229=PMID:11375975, GO:0005789=GO_REF:0000039, GO:0016023=PMID:14581450, GO:0016021=GO_REF:0000037, GO:0031673=GO_REF:0000039} Q5T0V7 Dystonin protein 20130413 {GO:0005515=IPI, GO:0005882=IEA, GO:0030424=IEA, GO:0030056=TAS, GO:0008090=IEA, GO:0030018=IEA, GO:0045104=NAS, GO:0042626=IEA, GO:0035371=IDA, GO:0005634=IDA, GO:0031122=IEA, GO:0030011=IMP, GO:0007409=IEA, GO:0005635=IEA, GO:0015629=IEA, GO:0005829=TAS, GO:0005737=IDA, GO:0009925=NAS, GO:0051010=IDA, GO:0030198=TAS, GO:0048870=IMP, GO:0007010=IMP, GO:0015630=IDA, GO:0007050=IEA, GO:0007155=IEA, GO:0005856=IEA, GO:0031252=IDA, GO:0005938=IEA, GO:0060053=IEA, GO:0031110=IEA, GO:0005509=IEA, GO:0009611=IDA, GO:0003779=IEA, GO:0008022=IPI, GO:0005524=IEA, GO:0005604=TAS, GO:0005178=IPI, GO:0007229=NAS, GO:0005789=IEA, GO:0016023=IDA, GO:0016021=IEA, GO:0031673=IEA} axonogenesis, cell adhesion, cell cycle arrest, cell motility, cytoplasmic microtubule organization, cytoskeleton organization, extracellular matrix organization, integrin-mediated signaling pathway, intermediate filament cytoskeleton organization, maintenance of cell polarity, regulation of microtubule polymerization or depolymerization, response to wounding, retrograde axon cargo transport H zone, Z disc, actin cytoskeleton, axon, basal plasma membrane, basement membrane, cell cortex, cell leading edge, cytoplasm, cytoplasmic membrane-bounded vesicle, cytoskeleton, cytosol, endoplasmic reticulum membrane, hemidesmosome, integral to membrane, intermediate filament, microtubule cytoskeleton, microtubule plus end, neurofilament cytoskeleton, nuclear envelope, nucleus ATP binding, ATPase activity, coupled to transmembrane movement of substances, actin binding, calcium ion binding, integrin binding, microtubule plus-end binding, protein C-terminus binding, protein binding Human UniProtKB-KW:KW-0009 DSTN PINC UniProtKB {GO:0051014=PMID:8399167, GO:0000910=GO_REF:0000019, GO:0008154=PMID:8399167, GO:0030836=GO_REF:0000019, GO:0006928=GO_REF:0000019, GO:0030042=GO_REF:0000002, GO:0003779=GO_REF:0000037, GO:0030864=GO_REF:0000019, GO:0015629=PMID:8399167} P60981 Destrin protein 20061109 {GO:0051014=TAS, GO:0000910=IEA, GO:0008154=TAS, GO:0030836=IEA, GO:0006928=IEA, GO:0030042=IEA, GO:0003779=IEA, GO:0030864=IEA, GO:0015629=TAS} actin filament depolymerization, actin filament severing, actin polymerization or depolymerization, cellular component movement, cytokinesis, positive regulation of actin filament depolymerization actin cytoskeleton, cortical actin cytoskeleton actin binding Human DSTYK HPA UniProtKB {GO:0005737=GO_REF:0000039, GO:0004672=GO_REF:0000002, GO:0004674=GO_REF:0000037, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0004712=GO_REF:0000003, GO:0045111=GO_REF:0000052, GO:0004713=GO_REF:0000037, GO:0005524=GO_REF:0000037} Q6XUX3 Dual serine/threonine and tyrosine protein kinase protein 20120912 {GO:0005737=IEA, GO:0004672=IEA, GO:0004674=IEA, GO:0005730=IDA, GO:0005634=IDA, GO:0004712=IEA, GO:0045111=IDA, GO:0004713=IEA, GO:0005524=IEA} cytoplasm, intermediate filament cytoskeleton, nucleolus, nucleus ATP binding, protein kinase activity, protein serine/threonine kinase activity, protein serine/threonine/tyrosine kinase activity, protein tyrosine kinase activity Human DTD1 HPA UniProtKB {GO:0005737=GO_REF:0000052, GO:0005730=GO_REF:0000052, GO:0016788=GO_REF:0000002, GO:0019478=GO_REF:0000002} Q8TEA8 D-tyrosyl-tRNA(Tyr) deacylase 1 protein 20101115 {GO:0005737=IDA, GO:0005730=IDA, GO:0016788=IEA, GO:0019478=IEA} D-amino acid catabolic process cytoplasm, nucleolus hydrolase activity, acting on ester bonds Human DTL HPA UniProtKB {GO:0005515=PMID:17041588, GO:0000209=PMID:18794347, GO:0006511=PMID:18794347, GO:0005813=PMID:17106265, GO:0031965=GO_REF:0000039, GO:0004842=PMID:20129063, GO:0006513=PMID:20129063, GO:0031572=PMID:17085480, GO:0005634=GO_REF:0000052, GO:0019985=PMID:20129063, GO:0006974=PMID:20129063, GO:0006260=GO_REF:0000037, GO:0005737=GO_REF:0000037, GO:0051726=PMID:17085480, GO:0031465=PMID:18794347, GO:0031464=PMID:18794347, GO:0009411=PMID:18794347} Q9NZJ0 Denticleless protein homolog protein 20101115 {GO:0005515=IPI, GO:0000209=IDA, GO:0006511=IDA, GO:0005813=IDA, GO:0031965=IEA, GO:0004842=IDA, GO:0006513=IDA, GO:0031572=IMP, GO:0005634=IDA, GO:0019985=IDA, GO:0006974=IDA, GO:0006260=IEA, GO:0005737=IEA, GO:0051726=IMP, GO:0031465=IDA, GO:0031464=IDA, GO:0009411=IDA} DNA replication, G2 DNA damage checkpoint, protein monoubiquitination, protein polyubiquitination, regulation of cell cycle, response to DNA damage stimulus, response to UV, translesion synthesis, ubiquitin-dependent protein catabolic process Cul4A-RING ubiquitin ligase complex, Cul4B-RING ubiquitin ligase complex, centrosome, cytoplasm, nuclear membrane, nucleus protein binding, ubiquitin-protein ligase activity Human DTNA PINC UniProtKB {GO:0005515=PMID:11353857, GO:0007165=PMID:10767327, GO:0043234=PMID:18468998, GO:0005737=GO_REF:0000039, GO:0030054=GO_REF:0000037, GO:0005886=GO_REF:0000039, GO:0005509=GO_REF:0000002, GO:0006941=PMID:10767327, GO:0007268=PMID:8845841, GO:0045202=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0007274=PMID:9119373} Q9Y4J8 Dystrobrevin alpha protein 20030904 {GO:0005515=IPI, GO:0007165=TAS, GO:0043234=IDA, GO:0005737=IEA, GO:0030054=IEA, GO:0005886=IEA, GO:0005509=IEA, GO:0006941=TAS, GO:0007268=TAS, GO:0045202=IEA, GO:0008270=IEA, GO:0007274=TAS} neuromuscular synaptic transmission, signal transduction, striated muscle contraction, synaptic transmission cell junction, cytoplasm, plasma membrane, protein complex, synapse calcium ion binding, protein binding, zinc ion binding Human DTNB UniProtKB UniProtKB {GO:0005737=GO_REF:0000039, GO:0005509=GO_REF:0000002, GO:0045202=GO_REF:0000019, GO:0008270=GO_REF:0000002} O60941 Dystrobrevin beta protein 20130413 {GO:0005737=IEA, GO:0005509=IEA, GO:0045202=IEA, GO:0008270=IEA} cytoplasm, synapse calcium ion binding, zinc ion binding Human UniProtKB-SubCell:SL-0086 DTNBP1 Reactome UniProtKB {GO:0005515=PMID:20921223, GO:0043005=PMID:16980328, GO:0033162=GO_REF:0000039, GO:0030424=GO_REF:0000024, GO:0048490=GO_REF:0000024, GO:0030054=GO_REF:0000037, GO:0032438=PMID:22203680, GO:0005634=GO_REF:0000024, GO:0014059=GO_REF:0000024, GO:0031175=PMID:16980328, GO:0005829=Reactome:REACT_19390, GO:0030426=GO_REF:0000024, GO:0005737=GO_REF:0000024, GO:0043197=GO_REF:0000024, GO:0045211=GO_REF:0000039, GO:0030672=GO_REF:0000024, GO:0031532=GO_REF:0000024, GO:0006892=Reactome:REACT_11235, GO:0014069=PMID:16980328, GO:0042383=GO_REF:0000024, GO:0033267=GO_REF:0000024, GO:0010628=GO_REF:0000024, GO:0016528=GO_REF:0000019, GO:0031083=PMID:22203680, GO:0007596=GO_REF:0000019, GO:0060159=GO_REF:0000024, GO:0048812=GO_REF:0000024, GO:0005789=GO_REF:0000024, GO:0060155=GO_REF:0000019, GO:0008089=GO_REF:0000024, GO:0001956=GO_REF:0000024, GO:0016044=Reactome:REACT_11123, GO:0010008=GO_REF:0000039} Q96EV8 Dysbindin protein 20090819 {GO:0005515=IPI, GO:0043005=IDA, GO:0033162=IEA, GO:0030424=ISS, GO:0048490=ISS, GO:0030054=IEA, GO:0032438=NAS, GO:0005634=ISS, GO:0014059=ISS, GO:0031175=IDA, GO:0005829=TAS, GO:0030426=ISS, GO:0005737=ISS, GO:0043197=ISS, GO:0045211=IEA, GO:0030672=ISS, GO:0031532=ISS, GO:0006892=TAS, GO:0014069=IDA, GO:0042383=ISS, GO:0033267=ISS, GO:0010628=ISS, GO:0016528=IEA, GO:0031083=IDA, GO:0007596=IEA, GO:0060159=ISS, GO:0048812=ISS, GO:0005789=ISS, GO:0060155=IEA, GO:0008089=ISS, GO:0001956=ISS, GO:0016044=TAS, GO:0010008=IEA} actin cytoskeleton reorganization, anterograde axon cargo transport, anterograde synaptic vesicle transport, blood coagulation, cellular membrane organization, melanosome organization, neuron projection development, neuron projection morphogenesis, platelet dense granule organization, positive regulation of gene expression, positive regulation of neurotransmitter secretion, post-Golgi vesicle-mediated transport, regulation of dopamine receptor signaling pathway, regulation of dopamine secretion BLOC-1 complex, axon, axon part, cell junction, cytoplasm, cytosol, dendritic spine, endoplasmic reticulum membrane, endosome membrane, growth cone, melanosome membrane, neuron projection, nucleus, postsynaptic density, postsynaptic membrane, sarcolemma, sarcoplasm, synaptic vesicle membrane protein binding Human DTWD1 null null {} null null null null {} null null null DTWD2 null null {} null null null null {} null null null DTX1 Reactome UniProtKB {GO:0005515=PMID:7671825, GO:0017124=GO_REF:0000037, GO:0016567=GO_REF:0000041, GO:0006366=PMID:9590294, GO:0016874=GO_REF:0000037, GO:0003713=PMID:9590294, GO:0005112=PMID:11564735, GO:0005634=GO_REF:0000039, GO:0006351=PMID:11564735, GO:0005829=Reactome:REACT_118743, GO:0005737=PMID:9590294, GO:0007219=Reactome:REACT_118859, GO:0045665=PMID:11564735, GO:0010001=GO_REF:0000019, GO:0045581=GO_REF:0000019, GO:0008270=GO_REF:0000002, GO:0007166=PMID:9590294, GO:0008593=PMID:11564735, GO:0031625=PMID:17028573} Q86Y01 E3 ubiquitin-protein ligase DTX1 protein 20130301 {GO:0005515=IPI, GO:0017124=IEA, GO:0016567=IEA, GO:0006366=TAS, GO:0016874=IEA, GO:0003713=TAS, GO:0005112=IDA, GO:0005634=IEA, GO:0006351=NAS, GO:0005829=TAS, GO:0005737=TAS, GO:0007219=TAS, GO:0045665=IGI, GO:0010001=IEA, GO:0045581=IEA, GO:0008270=IEA, GO:0007166=TAS, GO:0008593=IGI, GO:0031625=IPI} Notch signaling pathway, cell surface receptor signaling pathway, glial cell differentiation, negative regulation of T cell differentiation, negative regulation of neuron differentiation, protein ubiquitination, regulation of Notch signaling pathway, transcription from RNA polymerase II promoter, transcription, DNA-dependent cytoplasm, cytosol, nucleus Notch binding, SH3 domain binding, ligase activity, protein binding, transcription coactivator activity, ubiquitin protein ligase binding, zinc ion binding Human DTX2 HPA UniProtKB {GO:0005515=PMID:19549727, GO:0005737=GO_REF:0000039, GO:0031965=GO_REF:0000052, GO:0016567=GO_REF:0000041, GO:0007219=GO_REF:0000019, GO:0016874=GO_REF:0000037, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0008270=GO_REF:0000002} Q86UW9 Probable E3 ubiquitin-protein ligase DTX2 protein 20120912 {GO:0005515=IPI, GO:0005737=IEA, GO:0031965=IDA, GO:0016567=IEA, GO:0007219=IEA, GO:0016874=IEA, GO:0005730=IDA, GO:0005634=IDA, GO:0008270=IEA} Notch signaling pathway, protein ubiquitination cytoplasm, nuclear membrane, nucleolus, nucleus ligase activity, protein binding, zinc ion binding Human DTX3 UniPathway UniProtKB {GO:0005737=GO_REF:0000039, GO:0016567=GO_REF:0000041, GO:0007219=GO_REF:0000019, GO:0016874=GO_REF:0000037, GO:0008270=GO_REF:0000002} Q8N9I9 Probable E3 ubiquitin-protein ligase DTX3 protein 20130413 {GO:0005737=IEA, GO:0016567=IEA, GO:0007219=IEA, GO:0016874=IEA, GO:0008270=IEA} Notch signaling pathway, protein ubiquitination cytoplasm ligase activity, zinc ion binding Human UniPathway:UPA00143 DTX3L UniProtKB UniProtKB {GO:0005515=PMID:23230272, GO:0042393=PMID:19818714, GO:0005737=PMID:16809771, GO:0004842=PMID:23230272, GO:0005634=PMID:16809771, GO:0008270=GO_REF:0000002, GO:0010390=PMID:19818714, GO:0006974=PMID:19818714, GO:0006302=PMID:23230272} Q8TDB6 E3 ubiquitin-protein ligase DTX3L protein 20130409 {GO:0005515=IPI, GO:0042393=IDA, GO:0005737=IDA, GO:0004842=IMP, GO:0005634=IDA, GO:0008270=IEA, GO:0010390=IDA, GO:0006974=IMP, GO:0006302=IMP} double-strand break repair, histone monoubiquitination, response to DNA damage stimulus cytoplasm, nucleus histone binding, protein binding, ubiquitin-protein ligase activity, zinc ion binding Human UniProtKB:Q8IXQ6 DTX4 UniPathway UniProtKB {GO:0005737=GO_REF:0000039, GO:0016567=GO_REF:0000041, GO:0007219=GO_REF:0000037, GO:0016874=GO_REF:0000037, GO:0008270=GO_REF:0000002} Q9Y2E6 E3 ubiquitin-protein ligase DTX4 protein 20130413 {GO:0005737=IEA, GO:0016567=IEA, GO:0007219=IEA, GO:0016874=IEA, GO:0008270=IEA} Notch signaling pathway, protein ubiquitination cytoplasm ligase activity, zinc ion binding Human UniPathway:UPA00143 DTYMK GOC UniProtKB {GO:0043627=GO_REF:0000019, GO:0015949=Reactome:REACT_21330, GO:0008283=PMID:8024690, GO:0050145=Reactome:REACT_636, GO:0055086=Reactome:REACT_1698, GO:0044281=Reactome:REACT_111217, GO:0006233=GO_REF:0000019, GO:0005524=GO_REF:0000037, GO:0006235=GO_REF:0000041, GO:0004798=PMID:8845311, GO:0005829=Reactome:REACT_636, GO:0046940=Reactome:REACT_636, GO:0005758=GO_REF:0000019, GO:0007049=PMID:8024690, GO:0071363=GO_REF:0000019, GO:0005759=GO_REF:0000019, GO:0045445=GO_REF:0000019, GO:0046686=GO_REF:0000019} P23919 Thymidylate kinase protein 20130413 {GO:0043627=IEA, GO:0015949=TAS, GO:0008283=TAS, GO:0050145=EXP, GO:0055086=TAS, GO:0044281=TAS, GO:0006233=IEA, GO:0005524=IEA, GO:0006235=IEA, GO:0004798=IDA, GO:0005829=TAS, GO:0046940=EXP, GO:0005758=IEA, GO:0007049=TAS, GO:0071363=IEA, GO:0005759=IEA, GO:0045445=IEA, GO:0046686=IEA} cell cycle, cell proliferation, cellular response to growth factor stimulus, dTDP biosynthetic process, dTTP biosynthetic process, myoblast differentiation, nucleobase-containing small molecule interconversion, nucleobase-containing small molecule metabolic process, nucleoside monophosphate phosphorylation, response to cadmium ion, response to estrogen stimulus, small molecule metabolic process cytosol, mitochondrial intermembrane space, mitochondrial matrix ATP binding, nucleoside phosphate kinase activity, thymidylate kinase activity Human DUOX1 UniProtKB UniProtKB {GO:0042554=PMID:10806195, GO:0050661=PMID:10806195, GO:0042335=PMID:11514595, GO:0005886=GO_REF:0000019, GO:0019221=PMID:16111680, GO:0072593=GO_REF:0000019, GO:0005509=GO_REF:0000002, GO:0050665=PMID:10806195, GO:0051591=GO_REF:0000024, GO:0016324=PMID:10806195, GO:0004601=GO_REF:0000037, GO:0042446=GO_REF:0000037, GO:0016174=PMID:10806195, GO:0006590=GO_REF:0000041, GO:0016021=GO_REF:0000037, GO:0042744=GO_REF:0000037, GO:0006979=GO_REF:0000002, GO:0055114=PMID:10601291, GO:0020037=GO_REF:0000002} Q9NRD9 Dual oxidase 1 protein 20060427 {GO:0042554=NAS, GO:0050661=NAS, GO:0042335=IMP, GO:0005886=IEA, GO:0019221=IDA, GO:0072593=IEA, GO:0005509=IEA, GO:0050665=NAS, GO:0051591=ISS, GO:0016324=NAS, GO:0004601=IEA, GO:0042446=IEA, GO:0016174=NAS, GO:0006590=IEA, GO:0016021=IEA, GO:0042744=IEA, GO:0006979=IEA, GO:0055114=TAS, GO:0020037=IEA} cuticle development, cytokine-mediated signaling pathway, hormone biosynthetic process, hydrogen peroxide biosynthetic process, hydrogen peroxide catabolic process, oxidation-reduction process, reactive oxygen species metabolic process, response to cAMP, response to oxidative stress, superoxide anion generation, thyroid hormone generation apical plasma membrane, integral to membrane, plasma membrane NAD(P)H oxidase activity, NADP binding, calcium ion binding, heme binding, peroxidase activity Human DUOX2 UniProtKB UniProtKB {GO:0048839=GO_REF:0000019, GO:0042335=GO_REF:0000024, GO:0005509=PMID:15972824, GO:0019221=PMID:16111680, GO:0030282=GO_REF:0000019, GO:0030878=GO_REF:0000019, GO:0009615=PMID:16111680, GO:0048855=GO_REF:0000019, GO:0051591=GO_REF:0000024, GO:0009566=GO_REF:0000019, GO:0016324=GO_REF:0000039, GO:0004601=GO_REF:0000037, GO:0035264=GO_REF:0000019, GO:0042446=GO_REF:0000037, GO:0016174=PMID:15972824, GO:0006590=GO_REF:0000041, GO:0016021=GO_REF:0000037, GO:0042744=GO_REF:0000037, GO:0055114=PMID:10601291, GO:0020037=GO_REF:0000002} Q9NRD8 Dual oxidase 2 protein 20060123 {GO:0048839=IEA, GO:0042335=ISS, GO:0005509=IDA, GO:0019221=IDA, GO:0030282=IEA, GO:0030878=IEA, GO:0009615=IDA, GO:0048855=IEA, GO:0051591=ISS, GO:0009566=IEA, GO:0016324=IEA, GO:0004601=IEA, GO:0035264=IEA, GO:0042446=IEA, GO:0016174=IDA, GO:0006590=IEA, GO:0016021=IEA, GO:0042744=IEA, GO:0055114=TAS, GO:0020037=IEA} adenohypophysis morphogenesis, bone mineralization, cuticle development, cytokine-mediated signaling pathway, fertilization, hormone biosynthetic process, hydrogen peroxide catabolic process, inner ear development, multicellular organism growth, oxidation-reduction process, response to cAMP, response to virus, thyroid gland development, thyroid hormone generation apical plasma membrane, integral to membrane NAD(P)H oxidase activity, calcium ion binding, heme binding, peroxidase activity Human UniProtKB:Q9NRD9 DUPD1 RefGenome UniProtKB {GO:0005737=GO_REF:0000039, GO:0006470=GO_REF:0000033, GO:0008138=GO_REF:0000033, GO:0004725=GO_REF:0000003} Q68J44 Dual specificity phosphatase DUPD1 protein 20110117 {GO:0005737=IEA, GO:0006470=IBA, GO:0008138=IBA, GO:0004725=IEA} protein dephosphorylation cytoplasm protein tyrosine phosphatase activity, protein tyrosine/serine/threonine phosphatase activity Human PANTHER:PTN000016642 DUS2L HPA UniProtKB {GO:0005739=GO_REF:0000019, GO:0003725=GO_REF:0000002, GO:0005737=GO_REF:0000052, GO:0005783=GO_REF:0000039, GO:0050660=GO_REF:0000002, GO:0017150=GO_REF:0000002} Q9NX74 "tRNA-dihydrouridine(20) synthase ""NAD(P)+""-like" protein 20111111 {GO:0005739=IEA, GO:0003725=IEA, GO:0005737=IDA, GO:0005783=IEA, GO:0050660=IEA, GO:0017150=IEA} cytoplasm, endoplasmic reticulum, mitochondrion double-stranded RNA binding, flavin adenine dinucleotide binding, tRNA dihydrouridine synthase activity Human DUS3L InterPro UniProtKB {GO:0050660=GO_REF:0000002, GO:0017150=GO_REF:0000002, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002} Q96G46 "tRNA-dihydrouridine(47) synthase ""NAD(P)(+)""-like" protein 20130413 {GO:0050660=IEA, GO:0017150=IEA, GO:0008270=IEA, GO:0003676=IEA} flavin adenine dinucleotide binding, nucleic acid binding, tRNA dihydrouridine synthase activity, zinc ion binding Human InterPro:IPR001269|InterPro:IPR018517 DUS4L InterPro UniProtKB {GO:0050660=GO_REF:0000002, GO:0017150=GO_REF:0000002} O95620 "tRNA-dihydrouridine(20a/20b) synthase ""NAD(P)+""-like" protein 20130413 {GO:0050660=IEA, GO:0017150=IEA} flavin adenine dinucleotide binding, tRNA dihydrouridine synthase activity Human InterPro:IPR001269|InterPro:IPR018517 DUSP1 IntAct UniProtKB {GO:0005515=PMID:16286470, GO:0042542=GO_REF:0000019, GO:0001706=GO_REF:0000033, GO:0043065=GO_REF:0000019, GO:0008330=GO_REF:0000019, GO:0042981=GO_REF:0000033, GO:0051384=GO_REF:0000019, GO:0033574=GO_REF:0000019, GO:0051591=GO_REF:0000019, GO:0032870=GO_REF:0000019, GO:0000188=GO_REF:0000033, GO:0035556=GO_REF:0000019, GO:0051592=GO_REF:0000019, GO:0007049=GO_REF:0000037, GO:0006470=GO_REF:0000033, GO:0005654=GO_REF:0000033, GO:0009416=GO_REF:0000019, GO:0032526=GO_REF:0000019, GO:0006979=PMID:1406996, GO:0032355=GO_REF:0000019, GO:0017017=GO_REF:0000033, GO:0004726=PMID:1406996} P28562 Dual specificity protein phosphatase 1 protein 20130415 {GO:0005515=IPI, GO:0042542=IEA, GO:0001706=IBA, GO:0043065=IEA, GO:0008330=IEA, GO:0042981=IBA, GO:0051384=IEA, GO:0033574=IEA, GO:0051591=IEA, GO:0032870=IEA, GO:0000188=IBA, GO:0035556=IEA, GO:0051592=IEA, GO:0007049=IEA, GO:0006470=IBA, GO:0005654=IBA, GO:0009416=IEA, GO:0032526=IEA, GO:0006979=TAS, GO:0032355=IEA, GO:0017017=IBA, GO:0004726=TAS} cell cycle, cellular response to hormone stimulus, endoderm formation, inactivation of MAPK activity, intracellular signal transduction, positive regulation of apoptotic process, protein dephosphorylation, regulation of apoptotic process, response to cAMP, response to calcium ion, response to estradiol stimulus, response to glucocorticoid stimulus, response to hydrogen peroxide, response to light stimulus, response to oxidative stress, response to retinoic acid, response to testosterone stimulus nucleoplasm MAP kinase tyrosine/serine/threonine phosphatase activity, non-membrane spanning protein tyrosine phosphatase activity, protein binding, protein tyrosine/threonine phosphatase activity Human UniProtKB:Q13309 DUSP10 HPA UniProtKB {GO:0033549=PMID:22375048, GO:0005794=GO_REF:0000052, GO:0005730=GO_REF:0000052, GO:0007254=PMID:10391943, GO:0006950=PMID:10391943, GO:0005634=GO_REF:0000052, GO:0060266=GO_REF:0000019, GO:0032873=GO_REF:0000033, GO:0000188=PMID:22375048, GO:0002819=GO_REF:0000019, GO:0016791=PMID:16806267, GO:0005737=PMID:10391943, GO:0006470=PMID:22375048, GO:0046329=GO_REF:0000033, GO:0032496=GO_REF:0000019, GO:0004721=PMID:10391943, GO:0043508=GO_REF:0000033, GO:0004725=GO_REF:0000003, GO:0017017=GO_REF:0000033} Q9Y6W6 Dual specificity protein phosphatase 10 protein 20101115 {GO:0033549=IDA, GO:0005794=IDA, GO:0005730=IDA, GO:0007254=TAS, GO:0006950=TAS, GO:0005634=IDA, GO:0060266=IEA, GO:0032873=IBA, GO:0000188=IDA, GO:0002819=IEA, GO:0016791=IDA, GO:0005737=TAS, GO:0006470=IDA, GO:0046329=IBA, GO:0032496=IEA, GO:0004721=TAS, GO:0043508=IBA, GO:0004725=IEA, GO:0017017=IBA} JNK cascade, inactivation of MAPK activity, negative regulation of JNK cascade, negative regulation of JUN kinase activity, negative regulation of respiratory burst involved in inflammatory response, negative regulation of stress-activated MAPK cascade, protein dephosphorylation, regulation of adaptive immune response, response to lipopolysaccharide, response to stress Golgi apparatus, cytoplasm, nucleolus, nucleus MAP kinase phosphatase activity, MAP kinase tyrosine/serine/threonine phosphatase activity, phosphatase activity, phosphoprotein phosphatase activity, protein tyrosine phosphatase activity Human DUSP11 GOC UniProtKB {GO:0006396=PMID:9685386, GO:0003723=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0008138=GO_REF:0000002, GO:0035335=PMID:9685386, GO:0004725=GO_REF:0000002} O75319 RNA/RNP complex-1-interacting phosphatase protein 20130413 {GO:0006396=TAS, GO:0003723=IEA, GO:0005634=IEA, GO:0008138=IEA, GO:0035335=TAS, GO:0004725=IEA} RNA processing, peptidyl-tyrosine dephosphorylation nucleus RNA binding, protein tyrosine phosphatase activity, protein tyrosine/serine/threonine phosphatase activity Human DUSP12 GOC UniProtKB {GO:0005737=GO_REF:0000033, GO:0006470=GO_REF:0000033, GO:0007254=GO_REF:0000033, GO:0005634=GO_REF:0000052, GO:0033133=GO_REF:0000033, GO:0008270=GO_REF:0000002, GO:0008138=GO_REF:0000033, GO:0019900=GO_REF:0000019, GO:0035335=PMID:10446167, GO:0006464=PMID:10446167, GO:0004725=GO_REF:0000003} Q9UNI6 Dual specificity protein phosphatase 12 protein 20130413 {GO:0005737=IBA, GO:0006470=IBA, GO:0007254=IRD, GO:0005634=IDA, GO:0033133=IBA, GO:0008270=IEA, GO:0008138=IBA, GO:0019900=IEA, GO:0035335=TAS, GO:0006464=TAS, GO:0004725=IEA} JNK cascade, cellular protein modification process, peptidyl-tyrosine dephosphorylation, positive regulation of glucokinase activity, protein dephosphorylation cytoplasm, nucleus kinase binding, protein tyrosine phosphatase activity, protein tyrosine/serine/threonine phosphatase activity, zinc ion binding Human DUSP13 PINC UniProtKB {GO:0005737=PMID:15252030, GO:0007126=PMID:10585869, GO:0006470=GO_REF:0000033, GO:0007283=PMID:10585869, GO:0008138=GO_REF:0000033, GO:0004725=GO_REF:0000003} Q9UII6 Dual specificity protein phosphatase 13 protein 20030904 {GO:0005737=IDA, GO:0007126=TAS, GO:0006470=IBA, GO:0007283=TAS, GO:0008138=IBA, GO:0004725=IEA} meiosis, protein dephosphorylation, spermatogenesis cytoplasm protein tyrosine phosphatase activity, protein tyrosine/serine/threonine phosphatase activity Human DUSP14 RefGenome UniProtKB {GO:0008138=GO_REF:0000033, GO:0035335=GO_REF:0000033, GO:0004725=GO_REF:0000003, GO:0017017=GO_REF:0000002} O95147 Dual specificity protein phosphatase 14 protein 20110118 {GO:0008138=IBA, GO:0035335=IBA, GO:0004725=IEA, GO:0017017=IEA} peptidyl-tyrosine dephosphorylation MAP kinase tyrosine/serine/threonine phosphatase activity, protein tyrosine phosphatase activity, protein tyrosine/serine/threonine phosphatase activity Human PANTHER:PTN000017471 DUSP15 IntAct UniProtKB {GO:0005515=PMID:17474147, GO:0005737=GO_REF:0000039, GO:0006470=GO_REF:0000033, GO:0005886=GO_REF:0000039, GO:0008138=GO_REF:0000033, GO:0004725=GO_REF:0000003} Q9H1R2 Dual specificity protein phosphatase 15 protein 20130415 {GO:0005515=IPI, GO:0005737=IEA, GO:0006470=IBA, GO:0005886=IEA, GO:0008138=IBA, GO:0004725=IEA} protein dephosphorylation cytoplasm, plasma membrane protein binding, protein tyrosine phosphatase activity, protein tyrosine/serine/threonine phosphatase activity Human UniProtKB:P19174 DUSP16 UniProtKB UniProtKB {GO:0045209=PMID:11489891, GO:0000188=PMID:11489891, GO:0016791=GO_REF:0000019, GO:0005737=PMID:11489891, GO:0006470=GO_REF:0000033, GO:0016311=PMID:11489891, GO:0016023=GO_REF:0000039, GO:0004721=PMID:11489891, GO:0005634=PMID:11489891, GO:0045204=PMID:11489891, GO:0017017=GO_REF:0000033, GO:0004725=GO_REF:0000003} Q9BY84 Dual specificity protein phosphatase 16 protein 20020502 {GO:0045209=TAS, GO:0000188=TAS, GO:0016791=IEA, GO:0005737=TAS, GO:0006470=IBA, GO:0016311=TAS, GO:0016023=IEA, GO:0004721=TAS, GO:0005634=TAS, GO:0045204=TAS, GO:0017017=IBA, GO:0004725=IEA} MAPK export from nucleus, MAPK phosphatase export from nucleus, leptomycin B sensitive, dephosphorylation, inactivation of MAPK activity, protein dephosphorylation cytoplasm, cytoplasmic membrane-bounded vesicle, nucleus MAP kinase tyrosine/serine/threonine phosphatase activity, phosphatase activity, phosphoprotein phosphatase activity, protein tyrosine phosphatase activity Human DUSP19 BHF-UCL UniProtKB {GO:0008330=GO_REF:0000019, GO:0007254=GO_REF:0000033, GO:0046330=GO_REF:0000024, GO:0031435=GO_REF:0000024, GO:0030295=GO_REF:0000024, GO:0000188=GO_REF:0000019, GO:0005737=GO_REF:0000033, GO:0008579=GO_REF:0000033, GO:0006470=GO_REF:0000033, GO:0046329=GO_REF:0000024, GO:0045860=GO_REF:0000024, GO:0004860=GO_REF:0000024, GO:0043507=GO_REF:0000024, GO:0006469=GO_REF:0000024, GO:0043410=GO_REF:0000024, GO:0043508=GO_REF:0000024, GO:0005078=GO_REF:0000024, GO:0004725=GO_REF:0000003} Q8WTR2 Dual specificity protein phosphatase 19 protein 20110301 {GO:0008330=IEA, GO:0007254=IBA, GO:0046330=ISS, GO:0031435=ISS, GO:0030295=ISS, GO:0000188=IEA, GO:0005737=IBA, GO:0008579=IBA, GO:0006470=IBA, GO:0046329=ISS, GO:0045860=ISS, GO:0004860=ISS, GO:0043507=ISS, GO:0006469=ISS, GO:0043410=ISS, GO:0043508=ISS, GO:0005078=ISS, GO:0004725=IEA} JNK cascade, inactivation of MAPK activity, negative regulation of JNK cascade, negative regulation of JUN kinase activity, negative regulation of protein kinase activity, positive regulation of JNK cascade, positive regulation of JUN kinase activity, positive regulation of MAPK cascade, positive regulation of protein kinase activity, protein dephosphorylation cytoplasm JUN kinase phosphatase activity, MAP-kinase scaffold activity, mitogen-activated protein kinase kinase kinase binding, protein kinase activator activity, protein kinase inhibitor activity, protein tyrosine phosphatase activity, protein tyrosine/threonine phosphatase activity Human UniProtKB:Q8K4T5 DUSP2 GOC UniProtKB {GO:0005515=PMID:21784977, GO:0000188=GO_REF:0000033, GO:0001706=GO_REF:0000033, GO:0006470=GO_REF:0000033, GO:0008330=PMID:8107850, GO:0005634=PMID:8107850, GO:0042981=GO_REF:0000033, GO:0005654=GO_REF:0000033, GO:0035335=PMID:7681221, GO:0017017=GO_REF:0000033, GO:0004725=GO_REF:0000003, GO:0051019=GO_REF:0000019} Q05923 Dual specificity protein phosphatase 2 protein 20130413 {GO:0005515=IPI, GO:0000188=IBA, GO:0001706=IBA, GO:0006470=IBA, GO:0008330=TAS, GO:0005634=TAS, GO:0042981=IBA, GO:0005654=IBA, GO:0035335=TAS, GO:0017017=IBA, GO:0004725=IEA, GO:0051019=IEA} endoderm formation, inactivation of MAPK activity, peptidyl-tyrosine dephosphorylation, protein dephosphorylation, regulation of apoptotic process nucleoplasm, nucleus MAP kinase tyrosine/serine/threonine phosphatase activity, mitogen-activated protein kinase binding, protein binding, protein tyrosine phosphatase activity, protein tyrosine/threonine phosphatase activity Human DUSP21 UniProtKB UniProtKB {GO:0005737=PMID:12408986, GO:0005743=GO_REF:0000039, GO:0005634=PMID:12408986, GO:0008138=GO_REF:0000033, GO:0035335=PMID:12408986, GO:0004725=PMID:12408986, GO:0017017=GO_REF:0000002} Q9H596 Dual specificity protein phosphatase 21 protein 20100322 {GO:0005737=IDA, GO:0005743=IEA, GO:0005634=IDA, GO:0008138=IBA, GO:0035335=IDA, GO:0004725=IDA, GO:0017017=IEA} peptidyl-tyrosine dephosphorylation cytoplasm, mitochondrial inner membrane, nucleus MAP kinase tyrosine/serine/threonine phosphatase activity, protein tyrosine phosphatase activity, protein tyrosine/serine/threonine phosphatase activity Human DUSP22 PINC UniProtKB {GO:0008283=PMID:9205128, GO:0046330=GO_REF:0000033, GO:0006915=PMID:9205128, GO:0005634=GO_REF:0000039, GO:0007275=PMID:9205128, GO:0000122=PMID:16636663, GO:0000188=PMID:9205128, GO:0005737=GO_REF:0000039, GO:0006470=GO_REF:0000033, GO:0042127=GO_REF:0000033, GO:0007179=GO_REF:0000033, GO:0008138=GO_REF:0000033, GO:0004725=GO_REF:0000003} Q9NRW4 Dual specificity protein phosphatase 22 protein 20030904 {GO:0008283=TAS, GO:0046330=IBA, GO:0006915=TAS, GO:0005634=IEA, GO:0007275=TAS, GO:0000122=IMP, GO:0000188=TAS, GO:0005737=IEA, GO:0006470=IBA, GO:0042127=IBA, GO:0007179=IBA, GO:0008138=IBA, GO:0004725=IEA} apoptotic process, cell proliferation, inactivation of MAPK activity, multicellular organismal development, negative regulation of transcription from RNA polymerase II promoter, positive regulation of JNK cascade, protein dephosphorylation, regulation of cell proliferation, transforming growth factor beta receptor signaling pathway cytoplasm, nucleus protein tyrosine phosphatase activity, protein tyrosine/serine/threonine phosphatase activity Human DUSP23 HPA UniProtKB {GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0008138=GO_REF:0000002, GO:0004725=GO_REF:0000003, GO:0043231=GO_REF:0000052, GO:0005829=GO_REF:0000039} Q9BVJ7 Dual specificity protein phosphatase 23 protein 20111111 {GO:0005730=IDA, GO:0005634=IDA, GO:0008138=IEA, GO:0004725=IEA, GO:0043231=IDA, GO:0005829=IEA} cytosol, intracellular membrane-bounded organelle, nucleolus, nucleus protein tyrosine phosphatase activity, protein tyrosine/serine/threonine phosphatase activity Human DUSP26 IntAct UniProtKB {GO:0005515=PMID:20562916, GO:0005739=GO_REF:0000019, GO:0005794=GO_REF:0000039, GO:0006470=GO_REF:0000033, GO:0005634=GO_REF:0000039, GO:0008138=GO_REF:0000033, GO:0004725=GO_REF:0000003} Q9BV47 Dual specificity protein phosphatase 26 protein 20130415 {GO:0005515=IPI, GO:0005739=IEA, GO:0005794=IEA, GO:0006470=IBA, GO:0005634=IEA, GO:0008138=IBA, GO:0004725=IEA} protein dephosphorylation Golgi apparatus, mitochondrion, nucleus protein binding, protein tyrosine phosphatase activity, protein tyrosine/serine/threonine phosphatase activity Human UniProtKB:P04637 DUSP28 RefGenome UniProtKB {GO:0006470=GO_REF:0000002, GO:0008138=GO_REF:0000033, GO:0035335=GO_REF:0000033, GO:0004725=GO_REF:0000003} Q4G0W2 Dual specificity phosphatase 28 protein 20110118 {GO:0006470=IEA, GO:0008138=IBA, GO:0035335=IBA, GO:0004725=IEA} peptidyl-tyrosine dephosphorylation, protein dephosphorylation protein tyrosine phosphatase activity, protein tyrosine/serine/threonine phosphatase activity Human PANTHER:PTN000017471 DUSP3 InterPro UniProtKB {GO:0033549=PMID:16604064, GO:0034142=Reactome:REACT_6894, GO:0005634=PMID:16604064, GO:0051403=Reactome:REACT_21308, GO:0035335=PMID:7876121, GO:0005829=PMID:12447358, GO:0043409=PMID:16604064, GO:0000188=PMID:16604064, GO:0002756=Reactome:REACT_6809, GO:0046329=PMID:11085983, GO:0006470=GO_REF:0000002, GO:0002755=Reactome:REACT_27215, GO:0070373=PMID:11085983, GO:0034138=Reactome:REACT_6783, GO:0004725=GO_REF:0000002, GO:0001772=PMID:12447358, GO:0048011=Reactome:REACT_11061, GO:0038124=Reactome:REACT_8006, GO:0038123=Reactome:REACT_8005, GO:0050868=PMID:12447358, GO:0034134=Reactome:REACT_7980, GO:0002224=Reactome:REACT_9020, GO:0050860=PMID:12447358, GO:0045931=PMID:16604064, GO:0045087=Reactome:REACT_6802, GO:0005654=Reactome:REACT_12439, GO:0034166=Reactome:REACT_9027, GO:0035666=Reactome:REACT_25281, GO:0008138=GO_REF:0000002, GO:0034146=Reactome:REACT_9061, GO:0034162=Reactome:REACT_9047} Q8IYJ9 DUSP3 protein protein 20130413 {GO:0033549=IMP, GO:0034142=TAS, GO:0005634=IDA, GO:0051403=TAS, GO:0035335=IDA, GO:0005829=IDA, GO:0043409=IMP, GO:0000188=IMP, GO:0002756=TAS, GO:0046329=IDA, GO:0006470=IEA, GO:0002755=TAS, GO:0070373=IDA, GO:0034138=TAS, GO:0004725=IEA, GO:0001772=IDA, GO:0048011=TAS, GO:0038124=TAS, GO:0038123=TAS, GO:0050868=IDA, GO:0034134=TAS, GO:0002224=TAS, GO:0050860=IDA, GO:0045931=IMP, GO:0045087=TAS, GO:0005654=TAS, GO:0034166=TAS, GO:0035666=TAS, GO:0008138=IEA, GO:0034146=TAS, GO:0034162=TAS} MyD88-dependent toll-like receptor signaling pathway, MyD88-independent toll-like receptor signaling pathway, TRIF-dependent toll-like receptor signaling pathway, inactivation of MAPK activity, innate immune response, negative regulation of ERK1 and ERK2 cascade, negative regulation of JNK cascade, negative regulation of MAPK cascade, negative regulation of T cell activation, negative regulation of T cell receptor signaling pathway, neurotrophin TRK receptor signaling pathway, peptidyl-tyrosine dephosphorylation, positive regulation of mitotic cell cycle, protein dephosphorylation, stress-activated MAPK cascade, toll-like receptor 10 signaling pathway, toll-like receptor 2 signaling pathway, toll-like receptor 3 signaling pathway, toll-like receptor 4 signaling pathway, toll-like receptor 5 signaling pathway, toll-like receptor 9 signaling pathway, toll-like receptor TLR1:TLR2 signaling pathway, toll-like receptor TLR6:TLR2 signaling pathway, toll-like receptor signaling pathway cytosol, immunological synapse, nucleoplasm, nucleus MAP kinase phosphatase activity, protein tyrosine phosphatase activity, protein tyrosine/serine/threonine phosphatase activity Human InterPro:IPR000340|InterPro:IPR020405|InterPro:IPR020417|InterPro:IPR020422|InterPro:IPR024950 DUSP4 Reactome UniProtKB {GO:0048011=Reactome:REACT_11061, GO:0001706=GO_REF:0000033, GO:0038124=Reactome:REACT_8006, GO:0034142=Reactome:REACT_6894, GO:0038123=Reactome:REACT_8005, GO:0034134=Reactome:REACT_7980, GO:0008330=PMID:7535768, GO:0005634=PMID:7535768, GO:0002224=Reactome:REACT_9020, GO:0051403=Reactome:REACT_21308, GO:0000188=GO_REF:0000033, GO:0002756=Reactome:REACT_6809, GO:0006470=GO_REF:0000033, GO:0000165=PMID:7535768, GO:0045087=Reactome:REACT_6802, GO:0002755=Reactome:REACT_27215, GO:0034166=Reactome:REACT_9027, GO:0005654=Reactome:REACT_12439, GO:0035666=Reactome:REACT_25281, GO:0034146=Reactome:REACT_9061, GO:0034138=Reactome:REACT_6783, GO:0034162=Reactome:REACT_9047, GO:0004725=GO_REF:0000003, GO:0017017=GO_REF:0000033} Q13115 Dual specificity protein phosphatase 4 protein 20130301 {GO:0048011=TAS, GO:0001706=IBA, GO:0038124=TAS, GO:0034142=TAS, GO:0038123=TAS, GO:0034134=TAS, GO:0008330=TAS, GO:0005634=TAS, GO:0002224=TAS, GO:0051403=TAS, GO:0000188=IBA, GO:0002756=TAS, GO:0006470=IBA, GO:0000165=TAS, GO:0045087=TAS, GO:0002755=TAS, GO:0034166=TAS, GO:0005654=TAS, GO:0035666=TAS, GO:0034146=TAS, GO:0034138=TAS, GO:0034162=TAS, GO:0004725=IEA, GO:0017017=IBA} MAPK cascade, MyD88-dependent toll-like receptor signaling pathway, MyD88-independent toll-like receptor signaling pathway, TRIF-dependent toll-like receptor signaling pathway, endoderm formation, inactivation of MAPK activity, innate immune response, neurotrophin TRK receptor signaling pathway, protein dephosphorylation, stress-activated MAPK cascade, toll-like receptor 10 signaling pathway, toll-like receptor 2 signaling pathway, toll-like receptor 3 signaling pathway, toll-like receptor 4 signaling pathway, toll-like receptor 5 signaling pathway, toll-like receptor 9 signaling pathway, toll-like receptor TLR1:TLR2 signaling pathway, toll-like receptor TLR6:TLR2 signaling pathway, toll-like receptor signaling pathway nucleoplasm, nucleus MAP kinase tyrosine/serine/threonine phosphatase activity, protein tyrosine phosphatase activity, protein tyrosine/threonine phosphatase activity Human DUSP5 GOC UniProtKB {GO:0000188=GO_REF:0000033, GO:0001706=GO_REF:0000033, GO:0006470=GO_REF:0000033, GO:0005654=GO_REF:0000033, GO:0035335=PMID:7961985, GO:0017017=GO_REF:0000033, GO:0004725=GO_REF:0000003} Q16690 Dual specificity protein phosphatase 5 protein 20130413 {GO:0000188=IBA, GO:0001706=IBA, GO:0006470=IBA, GO:0005654=IBA, GO:0035335=TAS, GO:0017017=IBA, GO:0004725=IEA} endoderm formation, inactivation of MAPK activity, peptidyl-tyrosine dephosphorylation, protein dephosphorylation nucleoplasm MAP kinase tyrosine/serine/threonine phosphatase activity, protein tyrosine phosphatase activity Human DUSP6 Reactome UniProtKB {GO:0014070=GO_REF:0000019, GO:0034142=Reactome:REACT_6894, GO:0042663=GO_REF:0000033, GO:0060420=GO_REF:0000033, GO:0009953=GO_REF:0000033, GO:0051409=PMID:10846176, GO:0051403=Reactome:REACT_21308, GO:0030154=GO_REF:0000019, GO:0035335=PMID:8670865, GO:0005829=GO_REF:0000033, GO:0000188=PMID:8670865, GO:0002756=Reactome:REACT_6809, GO:0005737=PMID:9788880, GO:0006470=GO_REF:0000019, GO:0002755=Reactome:REACT_27215, GO:0070373=PMID:18771677, GO:0034138=Reactome:REACT_6783, GO:0004725=GO_REF:0000003, GO:0017017=PMID:8670865, GO:0048011=Reactome:REACT_11061, GO:0038124=Reactome:REACT_8006, GO:0043065=PMID:10846176, GO:0038123=Reactome:REACT_8005, GO:0042493=GO_REF:0000019, GO:0034134=Reactome:REACT_7980, GO:0070848=GO_REF:0000019, GO:0002224=Reactome:REACT_9020, GO:0040036=GO_REF:0000033, GO:0045087=Reactome:REACT_6802, GO:0001933=GO_REF:0000019, GO:0035666=Reactome:REACT_25281, GO:0034166=Reactome:REACT_9027, GO:0005654=Reactome:REACT_12439, GO:0008138=GO_REF:0000019, GO:0034146=Reactome:REACT_9061, GO:0034162=Reactome:REACT_9047} Q16828 Dual specificity protein phosphatase 6 protein 20130301 {GO:0014070=IEA, GO:0034142=TAS, GO:0042663=IBA, GO:0060420=IBA, GO:0009953=IBA, GO:0051409=IEP, GO:0051403=TAS, GO:0030154=IEA, GO:0035335=IDA, GO:0005829=IBA, GO:0000188=IDA, GO:0002756=TAS, GO:0005737=IDA, GO:0006470=IEA, GO:0002755=TAS, GO:0070373=IMP, GO:0034138=TAS, GO:0004725=IEA, GO:0017017=IDA, GO:0048011=TAS, GO:0038124=TAS, GO:0043065=IDA, GO:0038123=TAS, GO:0042493=IEA, GO:0034134=TAS, GO:0070848=IEA, GO:0002224=TAS, GO:0040036=IBA, GO:0045087=TAS, GO:0001933=IEA, GO:0035666=TAS, GO:0034166=TAS, GO:0005654=TAS, GO:0008138=IEA, GO:0034146=TAS, GO:0034162=TAS} MyD88-dependent toll-like receptor signaling pathway, MyD88-independent toll-like receptor signaling pathway, TRIF-dependent toll-like receptor signaling pathway, cell differentiation, dorsal/ventral pattern formation, inactivation of MAPK activity, innate immune response, negative regulation of ERK1 and ERK2 cascade, negative regulation of protein phosphorylation, neurotrophin TRK receptor signaling pathway, peptidyl-tyrosine dephosphorylation, positive regulation of apoptotic process, protein dephosphorylation, regulation of endodermal cell fate specification, regulation of fibroblast growth factor receptor signaling pathway, regulation of heart growth, response to drug, response to growth factor stimulus, response to nitrosative stress, response to organic cyclic compound, stress-activated MAPK cascade, toll-like receptor 10 signaling pathway, toll-like receptor 2 signaling pathway, toll-like receptor 3 signaling pathway, toll-like receptor 4 signaling pathway, toll-like receptor 5 signaling pathway, toll-like receptor 9 signaling pathway, toll-like receptor TLR1:TLR2 signaling pathway, toll-like receptor TLR6:TLR2 signaling pathway, toll-like receptor signaling pathway cytoplasm, cytosol, nucleoplasm MAP kinase tyrosine/serine/threonine phosphatase activity, protein tyrosine phosphatase activity, protein tyrosine/serine/threonine phosphatase activity Human DUSP7 IntAct UniProtKB {GO:0005515=PMID:12907755, GO:0048011=Reactome:REACT_11061, GO:0038124=Reactome:REACT_8006, GO:0034142=Reactome:REACT_6894, GO:0038123=Reactome:REACT_8005, GO:0034134=Reactome:REACT_7980, GO:0002224=Reactome:REACT_9020, GO:0051403=Reactome:REACT_21308, GO:0035335=PMID:9788880, GO:0005829=PMID:9788880, GO:0000188=GO_REF:0000033, GO:0002756=Reactome:REACT_6809, GO:0006470=GO_REF:0000002, GO:0043407=PMID:9788880, GO:0002755=Reactome:REACT_27215, GO:0045087=Reactome:REACT_6802, GO:0034166=Reactome:REACT_9027, GO:0005654=Reactome:REACT_12439, GO:0035666=Reactome:REACT_25281, GO:0034146=Reactome:REACT_9061, GO:0034138=Reactome:REACT_6783, GO:0034162=Reactome:REACT_9047, GO:0017017=PMID:9788880, GO:0004725=GO_REF:0000003} Q16829 Dual specificity protein phosphatase 7 protein 20130415 {GO:0005515=IPI, GO:0048011=TAS, GO:0038124=TAS, GO:0034142=TAS, GO:0038123=TAS, GO:0034134=TAS, GO:0002224=TAS, GO:0051403=TAS, GO:0035335=IDA, GO:0005829=IDA, GO:0000188=IBA, GO:0002756=TAS, GO:0006470=IEA, GO:0043407=IDA, GO:0002755=TAS, GO:0045087=TAS, GO:0034166=TAS, GO:0005654=TAS, GO:0035666=TAS, GO:0034146=TAS, GO:0034138=TAS, GO:0034162=TAS, GO:0017017=IDA, GO:0004725=IEA} MyD88-dependent toll-like receptor signaling pathway, MyD88-independent toll-like receptor signaling pathway, TRIF-dependent toll-like receptor signaling pathway, inactivation of MAPK activity, innate immune response, negative regulation of MAP kinase activity, neurotrophin TRK receptor signaling pathway, peptidyl-tyrosine dephosphorylation, protein dephosphorylation, stress-activated MAPK cascade, toll-like receptor 10 signaling pathway, toll-like receptor 2 signaling pathway, toll-like receptor 3 signaling pathway, toll-like receptor 4 signaling pathway, toll-like receptor 5 signaling pathway, toll-like receptor 9 signaling pathway, toll-like receptor TLR1:TLR2 signaling pathway, toll-like receptor TLR6:TLR2 signaling pathway, toll-like receptor signaling pathway cytosol, nucleoplasm MAP kinase tyrosine/serine/threonine phosphatase activity, protein binding, protein tyrosine phosphatase activity Human UniProtKB:P10912 DUSP8 GOC UniProtKB {GO:0000188=GO_REF:0000033, GO:0005737=GO_REF:0000033, GO:0006470=GO_REF:0000033, GO:0005634=GO_REF:0000033, GO:0035335=PMID:7561881, GO:0017017=GO_REF:0000033, GO:0004725=GO_REF:0000003} Q13202 Dual specificity protein phosphatase 8 protein 20130413 {GO:0000188=IBA, GO:0005737=IBA, GO:0006470=IBA, GO:0005634=IBA, GO:0035335=TAS, GO:0017017=IBA, GO:0004725=IEA} inactivation of MAPK activity, peptidyl-tyrosine dephosphorylation, protein dephosphorylation cytoplasm, nucleus MAP kinase tyrosine/serine/threonine phosphatase activity, protein tyrosine phosphatase activity Human DUSP9 HPA UniProtKB {GO:0000188=GO_REF:0000033, GO:0005737=PMID:9030581, GO:0006470=GO_REF:0000033, GO:0005783=GO_REF:0000052, GO:0007254=PMID:9030581, GO:0005634=PMID:9030581, GO:0004721=PMID:9030581, GO:0004725=GO_REF:0000003, GO:0017017=GO_REF:0000033, GO:0005829=GO_REF:0000033} Q99956 Dual specificity protein phosphatase 9 protein 20080818 {GO:0000188=IBA, GO:0005737=TAS, GO:0006470=IBA, GO:0005783=IDA, GO:0007254=TAS, GO:0005634=TAS, GO:0004721=TAS, GO:0004725=IEA, GO:0017017=IBA, GO:0005829=IBA} JNK cascade, inactivation of MAPK activity, protein dephosphorylation cytoplasm, cytosol, endoplasmic reticulum, nucleus MAP kinase tyrosine/serine/threonine phosphatase activity, phosphoprotein phosphatase activity, protein tyrosine phosphatase activity Human DUT IntAct UniProtKB {GO:0005515=PMID:19060904, GO:0046080=GO_REF:0000002, GO:0005634=PMID:8631816, GO:0055086=Reactome:REACT_1698, GO:0044281=Reactome:REACT_111217, GO:0006226=GO_REF:0000041, GO:0005739=GO_REF:0000039, GO:0006260=PMID:1325640, GO:0006139=PMID:1325640, GO:0046134=Reactome:REACT_21376, GO:0004170=Reactome:REACT_150, GO:0005654=Reactome:REACT_150, GO:0006206=Reactome:REACT_957} P33316 Deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial protein 20130415 {GO:0005515=IPI, GO:0046080=IEA, GO:0005634=TAS, GO:0055086=TAS, GO:0044281=TAS, GO:0006226=IEA, GO:0005739=IEA, GO:0006260=TAS, GO:0006139=TAS, GO:0046134=TAS, GO:0004170=EXP, GO:0005654=TAS, GO:0006206=TAS} DNA replication, dUMP biosynthetic process, dUTP metabolic process, nucleobase-containing compound metabolic process, nucleobase-containing small molecule metabolic process, pyrimidine nucleobase metabolic process, pyrimidine nucleoside biosynthetic process, small molecule metabolic process mitochondrion, nucleoplasm, nucleus dUTP diphosphatase activity, protein binding Human UniProtKB:Q6ZVK8 DUX4 UniProtKB UniProtKB {GO:0000976=GO_REF:0000002, GO:0003700=GO_REF:0000002, GO:0005634=GO_REF:0000039, GO:0006351=GO_REF:0000037} Q9UBX2 Double homeobox protein 4 protein 20130413 {GO:0000976=IEA, GO:0003700=IEA, GO:0005634=IEA, GO:0006351=IEA} transcription, DNA-dependent nucleus sequence-specific DNA binding transcription factor activity, transcription regulatory region sequence-specific DNA binding Human UniProtKB-SubCell:SL-0191 DVL1 BHF-UCL UniProtKB {GO:0005515=PMID:20412773, GO:0034504=PMID:10330181, GO:0006366=PMID:11742073, GO:0090263=GO_REF:0000019, GO:0045202=GO_REF:0000024, GO:0035372=GO_REF:0000019, GO:0031122=GO_REF:0000019, GO:0042802=PMID:10330181, GO:0005109=PMID:19388021, GO:0007411=GO_REF:0000033, GO:0043025=GO_REF:0000033, GO:0005938=GO_REF:0000033, GO:0019901=PMID:19643732, GO:0060134=GO_REF:0000019, GO:0050808=GO_REF:0000024, GO:0001505=GO_REF:0000024, GO:0010976=GO_REF:0000019, GO:0035176=GO_REF:0000019, GO:0019899=PMID:19643732, GO:0045893=PMID:17593335, GO:0071340=GO_REF:0000033, GO:0032091=PMID:19643732, GO:0030424=GO_REF:0000033, GO:0030136=GO_REF:0000033, GO:0030177=PMID:11113207, GO:0048675=GO_REF:0000033, GO:0030425=GO_REF:0000033, GO:0007269=GO_REF:0000024, GO:0030426=GO_REF:0000033, GO:0005829=GO_REF:0000039, GO:0035556=GO_REF:0000002, GO:0060026=GO_REF:0000033, GO:0007528=GO_REF:0000024, GO:0048668=GO_REF:0000033, GO:0090103=GO_REF:0000033, GO:0004871=GO_REF:0000002, GO:0022007=GO_REF:0000019, GO:0060070=PMID:17593335, GO:0060071=PMID:12805222, GO:0005874=GO_REF:0000033, GO:0090179=GO_REF:0000033, GO:0031410=PMID:11113207, GO:0016328=PMID:20177058, GO:0048813=GO_REF:0000024, GO:0048365=GO_REF:0000033, GO:0021915=PMID:8817329, GO:0016023=GO_REF:0000024, GO:0043113=GO_REF:0000024, GO:0006469=PMID:10330181} O14640 Segment polarity protein dishevelled homolog DVL-1 protein 20101206 {GO:0005515=IPI, GO:0034504=IMP, GO:0006366=IDA, GO:0090263=IEA, GO:0045202=ISS, GO:0035372=IEA, GO:0031122=IEA, GO:0042802=IPI, GO:0005109=IPI, GO:0007411=IBA, GO:0043025=IBA, GO:0005938=IBA, GO:0019901=IPI, GO:0060134=IEA, GO:0050808=ISS, GO:0001505=ISS, GO:0010976=IEA, GO:0035176=IEA, GO:0019899=IPI, GO:0045893=IDA, GO:0071340=IBA, GO:0032091=IDA, GO:0030424=IBA, GO:0030136=IBA, GO:0030177=IDA, GO:0048675=IBA, GO:0030425=IBA, GO:0007269=ISS, GO:0030426=IBA, GO:0005829=IEA, GO:0035556=IEA, GO:0060026=IBA, GO:0007528=ISS, GO:0048668=IBA, GO:0090103=IBA, GO:0004871=IEA, GO:0022007=IEA, GO:0060070=IDA, GO:0060071=IDA, GO:0005874=IBA, GO:0090179=IBA, GO:0031410=IDA, GO:0016328=IDA, GO:0048813=ISS, GO:0048365=IBA, GO:0021915=IEP, GO:0016023=ISS, GO:0043113=ISS, GO:0006469=IDA} Wnt receptor signaling pathway, planar cell polarity pathway, axon extension, axon guidance, canonical Wnt receptor signaling pathway, cochlea morphogenesis, collateral sprouting, convergent extension, convergent extension involved in neural plate elongation, cytoplasmic microtubule organization, dendrite morphogenesis, intracellular signal transduction, negative regulation of protein binding, negative regulation of protein kinase activity, neural tube development, neuromuscular junction development, neurotransmitter secretion, planar cell polarity pathway involved in neural tube closure, positive regulation of Wnt receptor signaling pathway, positive regulation of canonical Wnt receptor signaling pathway, positive regulation of neuron projection development, positive regulation of transcription, DNA-dependent, prepulse inhibition, protein localization to microtubule, protein localization to nucleus, receptor clustering, regulation of neurotransmitter levels, skeletal muscle acetylcholine-gated channel clustering, social behavior, synapse organization, transcription from RNA polymerase II promoter axon, cell cortex, clathrin-coated vesicle, cytoplasmic membrane-bounded vesicle, cytoplasmic vesicle, cytosol, dendrite, growth cone, lateral plasma membrane, microtubule, neuronal cell body, synapse Rac GTPase binding, enzyme binding, frizzled binding, identical protein binding, protein binding, protein kinase binding, signal transducer activity Human UniProtKB:Q9GZV5 DVL2 BHF-UCL UniProtKB {GO:0005515=PMID:20412773, GO:0021535=GO_REF:0000033, GO:0005886=GO_REF:0000033, GO:0006366=PMID:11742073, GO:0061098=GO_REF:0000019, GO:0090263=GO_REF:0000019, GO:0030136=GO_REF:0000033, GO:0005634=GO_REF:0000024, GO:0043621=GO_REF:0000019, GO:0042802=PMID:16189514, GO:0005829=Reactome:REACT_118667, GO:0007507=GO_REF:0000024, GO:0035556=GO_REF:0000002, GO:0005622=GO_REF:0000002, GO:0005109=PMID:19388021, GO:0044340=PMID:18787224, GO:0005737=PMID:9192851, GO:0051091=PMID:17593335, GO:0060026=GO_REF:0000033, GO:0090103=GO_REF:0000033, GO:0043507=PMID:19137009, GO:0004871=GO_REF:0000002, GO:0022007=GO_REF:0000019, GO:0016055=PMID:16446366, GO:0060070=PMID:17593335, GO:0005938=GO_REF:0000033, GO:0060071=PMID:12805222, GO:0007379=GO_REF:0000024, GO:0019904=GO_REF:0000019, GO:0090179=GO_REF:0000033, GO:0001843=GO_REF:0000024, GO:0045177=GO_REF:0000033, GO:0007275=GO_REF:0000002, GO:0035329=Reactome:REACT_118607, GO:0003151=GO_REF:0000024, GO:0003007=GO_REF:0000033, GO:0001934=PMID:20137080, GO:0034613=GO_REF:0000019, GO:0045893=PMID:17593335, GO:0035567=PMID:19137009} O14641 Segment polarity protein dishevelled homolog DVL-2 protein 20100930 {GO:0005515=IPI, GO:0021535=IBA, GO:0005886=IBA, GO:0006366=IDA, GO:0061098=IEA, GO:0090263=IEA, GO:0030136=IBA, GO:0005634=ISS, GO:0043621=IEA, GO:0042802=IPI, GO:0005829=TAS, GO:0007507=ISS, GO:0035556=IEA, GO:0005622=IEA, GO:0005109=IPI, GO:0044340=IDA, GO:0005737=IDA, GO:0051091=IDA, GO:0060026=IBA, GO:0090103=IBA, GO:0043507=IMP, GO:0004871=IEA, GO:0022007=IEA, GO:0016055=IGI, GO:0060070=IDA, GO:0005938=IBA, GO:0060071=IDA, GO:0007379=ISS, GO:0019904=IEA, GO:0090179=IBA, GO:0001843=ISS, GO:0045177=IBA, GO:0007275=IEA, GO:0035329=TAS, GO:0003151=ISS, GO:0003007=IBA, GO:0001934=IMP, GO:0034613=IEA, GO:0045893=IDA, GO:0035567=IMP} Wnt receptor signaling pathway, Wnt receptor signaling pathway, planar cell polarity pathway, canonical Wnt receptor signaling pathway, canonical Wnt receptor signaling pathway involved in regulation of cell proliferation, cell migration in hindbrain, cellular protein localization, cochlea morphogenesis, convergent extension, convergent extension involved in neural plate elongation, heart development, heart morphogenesis, hippo signaling cascade, intracellular signal transduction, multicellular organismal development, neural tube closure, non-canonical Wnt receptor signaling pathway, outflow tract morphogenesis, planar cell polarity pathway involved in neural tube closure, positive regulation of JUN kinase activity, positive regulation of canonical Wnt receptor signaling pathway, positive regulation of protein phosphorylation, positive regulation of protein tyrosine kinase activity, positive regulation of sequence-specific DNA binding transcription factor activity, positive regulation of transcription, DNA-dependent, segment specification, transcription from RNA polymerase II promoter apical part of cell, cell cortex, clathrin-coated vesicle, cytoplasm, cytosol, intracellular, nucleus, plasma membrane frizzled binding, identical protein binding, protein binding, protein domain specific binding, protein self-association, signal transducer activity Human DVL3 BHF-UCL UniProtKB {GO:0005515=PMID:20412773, GO:0008013=PMID:10644691, GO:0038031=GO_REF:0000024, GO:0002020=PMID:20227366, GO:0035556=GO_REF:0000002, GO:0005622=GO_REF:0000002, GO:0005109=PMID:19388021, GO:0060026=GO_REF:0000033, GO:0005737=GO_REF:0000019, GO:0090103=GO_REF:0000033, GO:0004871=GO_REF:0000002, GO:0043507=PMID:19137009, GO:0016055=PMID:10644691, GO:0005938=GO_REF:0000033, GO:0060070=PMID:20137080, GO:0060071=PMID:12805222, GO:0046982=PMID:19137009, GO:0042493=GO_REF:0000019, GO:0090179=GO_REF:0000033, GO:0005102=PMID:17030191, GO:0007275=GO_REF:0000002, GO:0003148=GO_REF:0000033, GO:0001934=PMID:20137080, GO:0045893=PMID:10644691, GO:0035567=PMID:19137009} Q92997 Segment polarity protein dishevelled homolog DVL-3 protein 20100806 {GO:0005515=IPI, GO:0008013=IDA, GO:0038031=ISS, GO:0002020=IPI, GO:0035556=IEA, GO:0005622=IEA, GO:0005109=IPI, GO:0060026=IBA, GO:0005737=IEA, GO:0090103=IBA, GO:0004871=IEA, GO:0043507=IMP, GO:0016055=IDA, GO:0005938=IBA, GO:0060070=IMP, GO:0060071=IDA, GO:0046982=IDA, GO:0042493=IEA, GO:0090179=IBA, GO:0005102=IPI, GO:0007275=IEA, GO:0003148=IBA, GO:0001934=IMP, GO:0045893=IDA, GO:0035567=IMP} Wnt receptor signaling pathway, Wnt receptor signaling pathway, planar cell polarity pathway, canonical Wnt receptor signaling pathway, cochlea morphogenesis, convergent extension, intracellular signal transduction, multicellular organismal development, non-canonical Wnt receptor signaling pathway, non-canonical Wnt receptor signaling pathway via JNK cascade, outflow tract septum morphogenesis, planar cell polarity pathway involved in neural tube closure, positive regulation of JUN kinase activity, positive regulation of protein phosphorylation, positive regulation of transcription, DNA-dependent, response to drug cell cortex, cytoplasm, intracellular beta-catenin binding, frizzled binding, protease binding, protein binding, protein heterodimerization activity, receptor binding, signal transducer activity Human DYDC1 null null {} null null null null {} null null null DYDC2 null null {} null null null null {} null null null DYM HPA UniProtKB {GO:0005515=PMID:21280149, GO:0060348=PMID:21280149, GO:0005737=GO_REF:0000052, GO:0005794=PMID:21280149, GO:0005886=GO_REF:0000052, GO:0007030=PMID:21280149, GO:0005634=GO_REF:0000052, GO:0019899=PMID:21280149} Q7RTS9 Dymeclin protein 20110516 {GO:0005515=IPI, GO:0060348=IMP, GO:0005737=IDA, GO:0005794=IDA, GO:0005886=IDA, GO:0007030=IMP, GO:0005634=IDA, GO:0019899=IPI} Golgi organization, bone development Golgi apparatus, cytoplasm, nucleus, plasma membrane enzyme binding, protein binding Human DYNC1H1 HPA UniProtKB {GO:0005515=PMID:21163940, GO:0008219=GO_REF:0000037, GO:0005813=PMID:21399614, GO:0005794=GO_REF:0000052, GO:0033962=GO_REF:0000024, GO:0042623=GO_REF:0000029, GO:0005874=PMID:21525035, GO:0003777=GO_REF:0000029, GO:0005524=GO_REF:0000037, GO:0005829=Reactome:REACT_120995, GO:0019886=Reactome:REACT_121399, GO:0005737=GO_REF:0000052, GO:0034063=GO_REF:0000024, GO:0000086=Reactome:REACT_2203, GO:0006810=GO_REF:0000037, GO:0005868=PMID:8666668, GO:0007052=PMID:8227145, GO:0000278=Reactome:REACT_152, GO:0007018=GO_REF:0000029} Q14204 Cytoplasmic dynein 1 heavy chain 1 protein 20080205 {GO:0005515=IPI, GO:0008219=IEA, GO:0005813=IDA, GO:0005794=IDA, GO:0033962=ISS, GO:0042623=NAS, GO:0005874=IDA, GO:0003777=NAS, GO:0005524=IEA, GO:0005829=TAS, GO:0019886=TAS, GO:0005737=IDA, GO:0034063=ISS, GO:0000086=TAS, GO:0006810=IEA, GO:0005868=NAS, GO:0007052=NAS, GO:0000278=TAS, GO:0007018=NAS} G2/M transition of mitotic cell cycle, antigen processing and presentation of exogenous peptide antigen via MHC class II, cell death, cytoplasmic mRNA processing body assembly, microtubule-based movement, mitotic cell cycle, mitotic spindle organization, stress granule assembly, transport Golgi apparatus, centrosome, cytoplasm, cytoplasmic dynein complex, cytosol, microtubule ATP binding, ATPase activity, coupled, microtubule motor activity, protein binding Human DYNC1I1 HGNC UniProtKB {GO:0005515=PMID:14985359, GO:0008017=GO_REF:0000024, GO:0048471=GO_REF:0000024, GO:0005874=GO_REF:0000037, GO:0003777=GO_REF:0000024, GO:0031982=PMID:20682791, GO:0005829=Reactome:REACT_120995, GO:0019886=Reactome:REACT_121399, GO:0000922=PMID:19229290, GO:0003774=PMID:10049579, GO:0047496=GO_REF:0000024, GO:0000777=GO_REF:0000039, GO:0000776=PMID:19229290, GO:0005868=GO_REF:0000024, GO:0007018=GO_REF:0000002} O14576 Cytoplasmic dynein 1 intermediate chain 1 protein 20070412 {GO:0005515=IPI, GO:0008017=ISS, GO:0048471=ISS, GO:0005874=IEA, GO:0003777=ISS, GO:0031982=IDA, GO:0005829=TAS, GO:0019886=TAS, GO:0000922=IDA, GO:0003774=TAS, GO:0047496=ISS, GO:0000777=IEA, GO:0000776=IDA, GO:0005868=ISS, GO:0007018=IEA} antigen processing and presentation of exogenous peptide antigen via MHC class II, microtubule-based movement, vesicle transport along microtubule condensed chromosome kinetochore, cytoplasmic dynein complex, cytosol, kinetochore, microtubule, perinuclear region of cytoplasm, spindle pole, vesicle microtubule binding, microtubule motor activity, motor activity, protein binding Human UniProtKB:Q63100 DYNC1I2 Reactome UniProtKB {GO:0005813=PMID:21399614, GO:0005874=PMID:21525035, GO:0003777=PMID:8522607, GO:0031982=PMID:20682791, GO:0005829=Reactome:REACT_120995, GO:0019886=Reactome:REACT_121399, GO:0005737=PMID:8522607, GO:0019048=GO_REF:0000037, GO:0000086=Reactome:REACT_2203, GO:0006810=GO_REF:0000037, GO:0005868=GO_REF:0000002, GO:0000278=Reactome:REACT_152, GO:0007018=PMID:8522607} Q13409 Cytoplasmic dynein 1 intermediate chain 2 protein 20130301 {GO:0005813=IDA, GO:0005874=IDA, GO:0003777=NAS, GO:0031982=IDA, GO:0005829=TAS, GO:0019886=TAS, GO:0005737=NAS, GO:0019048=IEA, GO:0000086=TAS, GO:0006810=IEA, GO:0005868=IEA, GO:0000278=TAS, GO:0007018=NAS} G2/M transition of mitotic cell cycle, antigen processing and presentation of exogenous peptide antigen via MHC class II, microtubule-based movement, mitotic cell cycle, transport, virus-host interaction centrosome, cytoplasm, cytoplasmic dynein complex, cytosol, microtubule, vesicle microtubule motor activity Human DYNC1LI1 HPA UniProtKB {GO:0005813=GO_REF:0000052, GO:0005886=GO_REF:0000052, GO:0005874=GO_REF:0000037, GO:0090267=PMID:19229290, GO:0005524=GO_REF:0000037, GO:0000922=PMID:19229290, GO:0003774=GO_REF:0000037, GO:0005737=GO_REF:0000052, GO:0007067=GO_REF:0000037, GO:0019048=GO_REF:0000037, GO:0006810=GO_REF:0000037, GO:0000777=GO_REF:0000039, GO:0000776=PMID:19229290, GO:0005868=PMID:19229290, GO:0051301=GO_REF:0000037} Q9Y6G9 Cytoplasmic dynein 1 light intermediate chain 1 protein 20101115 {GO:0005813=IDA, GO:0005886=IDA, GO:0005874=IEA, GO:0090267=IMP, GO:0005524=IEA, GO:0000922=IDA, GO:0003774=IEA, GO:0005737=IDA, GO:0007067=IEA, GO:0019048=IEA, GO:0006810=IEA, GO:0000777=IEA, GO:0000776=IDA, GO:0005868=IDA, GO:0051301=IEA} cell division, mitosis, positive regulation of mitotic cell cycle spindle assembly checkpoint, transport, virus-host interaction centrosome, condensed chromosome kinetochore, cytoplasm, cytoplasmic dynein complex, kinetochore, microtubule, plasma membrane, spindle pole ATP binding, motor activity Human DYNC1LI2 Reactome UniProtKB {GO:0019886=Reactome:REACT_121399, GO:0005813=PMID:21399614, GO:0051642=GO_REF:0000019, GO:0003774=GO_REF:0000037, GO:0005874=GO_REF:0000037, GO:0006810=GO_REF:0000037, GO:0000226=GO_REF:0000019, GO:0005868=PMID:7738094, GO:0005524=GO_REF:0000037, GO:0005829=Reactome:REACT_120995} O43237 Cytoplasmic dynein 1 light intermediate chain 2 protein 20130301 {GO:0019886=TAS, GO:0005813=IDA, GO:0051642=IEA, GO:0003774=IEA, GO:0005874=IEA, GO:0006810=IEA, GO:0000226=IEA, GO:0005868=TAS, GO:0005524=IEA, GO:0005829=TAS} antigen processing and presentation of exogenous peptide antigen via MHC class II, centrosome localization, microtubule cytoskeleton organization, transport centrosome, cytoplasmic dynein complex, cytosol, microtubule ATP binding, motor activity Human DYNC2H1 Reactome UniProtKB {GO:0007368=GO_REF:0000019, GO:0005794=PMID:8666668, GO:0005886=GO_REF:0000039, GO:0001539=GO_REF:0000002, GO:0005874=PMID:21525035, GO:0045177=GO_REF:0000019, GO:0031512=GO_REF:0000019, GO:0009953=GO_REF:0000019, GO:0030326=GO_REF:0000019, GO:0035085=GO_REF:0000039, GO:0003777=GO_REF:0000002, GO:0005524=GO_REF:0000037, GO:0005829=Reactome:REACT_120995, GO:0019886=Reactome:REACT_121399, GO:0042384=GO_REF:0000019, GO:0003774=PMID:8666668, GO:0030286=GO_REF:0000037, GO:0008105=GO_REF:0000019, GO:0016485=GO_REF:0000019, GO:0030031=GO_REF:0000002, GO:0007030=PMID:8666668, GO:0030900=GO_REF:0000019, GO:0016887=GO_REF:0000002, GO:0007018=GO_REF:0000002} Q8NCM8 Cytoplasmic dynein 2 heavy chain 1 protein 20130301 {GO:0007368=IEA, GO:0005794=IDA, GO:0005886=IEA, GO:0001539=IEA, GO:0005874=IDA, GO:0045177=IEA, GO:0031512=IEA, GO:0009953=IEA, GO:0030326=IEA, GO:0035085=IEA, GO:0003777=IEA, GO:0005524=IEA, GO:0005829=TAS, GO:0019886=TAS, GO:0042384=IEA, GO:0003774=NAS, GO:0030286=IEA, GO:0008105=IEA, GO:0016485=IEA, GO:0030031=IEA, GO:0007030=IDA, GO:0030900=IEA, GO:0016887=IEA, GO:0007018=IEA} Golgi organization, antigen processing and presentation of exogenous peptide antigen via MHC class II, asymmetric protein localization, cell projection assembly, ciliary or flagellar motility, cilium assembly, determination of left/right symmetry, dorsal/ventral pattern formation, embryonic limb morphogenesis, forebrain development, microtubule-based movement, protein processing Golgi apparatus, apical part of cell, cilium axoneme, cytosol, dynein complex, microtubule, motile primary cilium, plasma membrane ATP binding, ATPase activity, microtubule motor activity, motor activity Human DYNC2LI1 BHF-UCL UniProtKB {GO:0005881=GO_REF:0000024, GO:0007368=GO_REF:0000019, GO:0045177=GO_REF:0000024, GO:0031512=GO_REF:0000024, GO:0072372=GO_REF:0000024, GO:0035085=GO_REF:0000024, GO:0005829=Reactome:REACT_120995, GO:0042384=GO_REF:0000019, GO:0019886=Reactome:REACT_121399, GO:0003774=GO_REF:0000037, GO:0005858=PMID:12802074, GO:0030990=GO_REF:0000024, GO:0005932=PMID:12802074} Q8TCX1 Cytoplasmic dynein 2 light intermediate chain 1 protein 20110316 {GO:0005881=ISS, GO:0007368=IEA, GO:0045177=ISS, GO:0031512=ISS, GO:0072372=ISS, GO:0035085=ISS, GO:0005829=TAS, GO:0042384=IEA, GO:0019886=TAS, GO:0003774=IEA, GO:0005858=ISS, GO:0030990=ISS, GO:0005932=ISS} antigen processing and presentation of exogenous peptide antigen via MHC class II, cilium assembly, determination of left/right symmetry apical part of cell, axonemal dynein complex, cilium axoneme, cytoplasmic microtubule, cytosol, intraflagellar transport particle, microtubule basal body, motile primary cilium, primary cilium motor activity colocalizes_with Human UniProtKB:Q7XA07 DYNLL1 IntAct UniProtKB {GO:0005515=PMID:18420585, GO:0072686=PMID:20133940, GO:0030036=PMID:8628263, GO:0005886=Reactome:REACT_1888, GO:0005634=PMID:15891768, GO:0009653=PMID:8628263, GO:0042803=GO_REF:0000019, GO:0005829=Reactome:REACT_120995, GO:0005739=GO_REF:0000039, GO:0019886=Reactome:REACT_121399, GO:0003774=GO_REF:0000037, GO:0005737=PMID:15891768, GO:1900740=Reactome:REACT_1650, GO:0008180=PMID:18850735, GO:0000086=Reactome:REACT_2203, GO:0006810=GO_REF:0000037, GO:0030235=GO_REF:0000019, GO:0007017=GO_REF:0000002, GO:0006355=GO_REF:0000037, GO:0005813=PMID:21399614, GO:0005875=GO_REF:0000002, GO:0005874=GO_REF:0000037, GO:0019904=GO_REF:0000019, GO:0006915=Reactome:REACT_578, GO:0007292=PMID:8628263, GO:0008022=GO_REF:0000019, GO:0097193=Reactome:REACT_964, GO:0006351=GO_REF:0000037, GO:0042326=PMID:18579519, GO:0016020=GO_REF:0000019, GO:0019048=GO_REF:0000037, GO:0000776=PMID:20133940, GO:0005868=GO_REF:0000024, GO:0000278=Reactome:REACT_152, GO:0019899=GO_REF:0000019} P63167 Dynein light chain 1, cytoplasmic protein 20130415 {GO:0005515=IPI, GO:0072686=IDA, GO:0030036=TAS, GO:0005886=TAS, GO:0005634=IDA, GO:0009653=TAS, GO:0042803=IEA, GO:0005829=TAS, GO:0005739=IEA, GO:0019886=TAS, GO:0003774=IEA, GO:0005737=IDA, GO:1900740=TAS, GO:0008180=IDA, GO:0000086=TAS, GO:0006810=IEA, GO:0030235=IEA, GO:0007017=IEA, GO:0006355=IEA, GO:0005813=IDA, GO:0005875=IEA, GO:0005874=IEA, GO:0019904=IEA, GO:0006915=TAS, GO:0007292=TAS, GO:0008022=IEA, GO:0097193=TAS, GO:0006351=IEA, GO:0042326=IDA, GO:0016020=IEA, GO:0019048=IEA, GO:0000776=IDA, GO:0005868=ISS, GO:0000278=TAS, GO:0019899=IEA} G2/M transition of mitotic cell cycle, actin cytoskeleton organization, anatomical structure morphogenesis, antigen processing and presentation of exogenous peptide antigen via MHC class II, apoptotic process, female gamete generation, intrinsic apoptotic signaling pathway, microtubule-based process, mitotic cell cycle, negative regulation of phosphorylation, positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway, regulation of transcription, DNA-dependent, transcription, DNA-dependent, transport, virus-host interaction centrosome, cytoplasm, cytoplasmic dynein complex, cytosol, kinetochore, membrane, microtubule, microtubule associated complex, mitochondrion, mitotic spindle, nucleus, plasma membrane, signalosome enzyme binding, motor activity, nitric-oxide synthase regulator activity, protein C-terminus binding, protein binding, protein domain specific binding, protein homodimerization activity Human UniProtKB:P63244 DYNLL2 Reactome UniProtKB {GO:0008092=GO_REF:0000019, GO:0005813=PMID:21399614, GO:0008039=GO_REF:0000019, GO:0005886=Reactome:REACT_1981, GO:0005874=GO_REF:0000037, GO:0006915=Reactome:REACT_578, GO:0016459=GO_REF:0000024, GO:0097193=Reactome:REACT_964, GO:0005829=Reactome:REACT_120995, GO:0019886=Reactome:REACT_121399, GO:0003774=GO_REF:0000037, GO:1900740=Reactome:REACT_2100, GO:0030286=GO_REF:0000037, GO:0006810=GO_REF:0000037, GO:0007017=GO_REF:0000002} Q96FJ2 Dynein light chain 2, cytoplasmic protein 20130213 {GO:0008092=IEA, GO:0005813=IDA, GO:0008039=IEA, GO:0005886=TAS, GO:0005874=IEA, GO:0006915=TAS, GO:0016459=ISS, GO:0097193=TAS, GO:0005829=TAS, GO:0019886=TAS, GO:0003774=IEA, GO:1900740=TAS, GO:0030286=IEA, GO:0006810=IEA, GO:0007017=IEA} antigen processing and presentation of exogenous peptide antigen via MHC class II, apoptotic process, intrinsic apoptotic signaling pathway, microtubule-based process, positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway, synaptic target recognition, transport centrosome, cytosol, dynein complex, microtubule, myosin complex, plasma membrane cytoskeletal protein binding, motor activity Human DYNLRB1 IntAct UniProtKB {GO:0005515=PMID:10198631, GO:0005813=PMID:21399614, GO:0005737=GO_REF:0000024, GO:0007632=GO_REF:0000024, GO:0005874=GO_REF:0000037, GO:0006810=GO_REF:0000037, GO:0005868=GO_REF:0000024, GO:0003777=PMID:11750132, GO:0007018=PMID:11750132, GO:0042802=GO_REF:0000019} Q9NP97 Dynein light chain roadblock-type 1 protein 20130415 {GO:0005515=IPI, GO:0005813=IDA, GO:0005737=ISS, GO:0007632=ISS, GO:0005874=IEA, GO:0006810=IEA, GO:0005868=ISS, GO:0003777=NAS, GO:0007018=NAS, GO:0042802=IEA} microtubule-based movement, transport, visual behavior centrosome, cytoplasm, cytoplasmic dynein complex, microtubule identical protein binding, microtubule motor activity, protein binding Human UniProtKB:O54918-2 DYNLRB2 UniProtKB UniProtKB {GO:0005874=GO_REF:0000037, GO:0006810=GO_REF:0000037, GO:0005868=GO_REF:0000024, GO:0003777=PMID:11750132, GO:0007018=PMID:11750132} Q8TF09 Dynein light chain roadblock-type 2 protein 20100507 {GO:0005874=IEA, GO:0006810=IEA, GO:0005868=ISS, GO:0003777=NAS, GO:0007018=NAS} microtubule-based movement, transport cytoplasmic dynein complex, microtubule microtubule motor activity Human UniProtKB:Q9DAJ5 DYNLT1 BHF-UCL UniProtKB {GO:0005515=PMID:10644691, GO:0005794=GO_REF:0000039, GO:0019060=PMID:18647839, GO:0005874=GO_REF:0000037, GO:0005819=GO_REF:0000039, GO:0000132=GO_REF:0000024, GO:0046718=GO_REF:0000037, GO:0042802=PMID:17965411, GO:0003774=GO_REF:0000037, GO:0007067=GO_REF:0000037, GO:0008277=GO_REF:0000024, GO:0050768=GO_REF:0000024, GO:0005868=GO_REF:0000024, GO:0051301=GO_REF:0000037} P63172 Dynein light chain Tctex-type 1 protein 20080919 {GO:0005515=IPI, GO:0005794=IEA, GO:0019060=IMP, GO:0005874=IEA, GO:0005819=IEA, GO:0000132=ISS, GO:0046718=IEA, GO:0042802=IPI, GO:0003774=IEA, GO:0007067=IEA, GO:0008277=ISS, GO:0050768=ISS, GO:0005868=ISS, GO:0051301=IEA} cell division, establishment of mitotic spindle orientation, intracellular transport of viral proteins in host cell, mitosis, negative regulation of neurogenesis, regulation of G-protein coupled receptor protein signaling pathway, viral entry into host cell Golgi apparatus, cytoplasmic dynein complex, microtubule, spindle identical protein binding, motor activity, protein binding Human UniProtKB:O14641 DYNLT3 HPA UniProtKB {GO:0005886=GO_REF:0000052, GO:0005874=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0042802=GO_REF:0000019, GO:0007346=GO_REF:0000024, GO:0005737=GO_REF:0000052, GO:0003774=GO_REF:0000037, GO:0007067=GO_REF:0000037, GO:0006810=GO_REF:0000037, GO:0000777=GO_REF:0000039, GO:0000776=PMID:17289665, GO:0005868=PMID:11425878, GO:0051301=GO_REF:0000037} P51808 Dynein light chain Tctex-type 3 protein 20090616 {GO:0005886=IDA, GO:0005874=IEA, GO:0005634=IEA, GO:0042802=IEA, GO:0007346=ISS, GO:0005737=IDA, GO:0003774=IEA, GO:0007067=IEA, GO:0006810=IEA, GO:0000777=IEA, GO:0000776=IDA, GO:0005868=IDA, GO:0051301=IEA} cell division, mitosis, regulation of mitotic cell cycle, transport condensed chromosome kinetochore, cytoplasm, cytoplasmic dynein complex, kinetochore, microtubule, nucleus, plasma membrane identical protein binding, motor activity Human DYRK1A BHF-UCL UniProtKB {GO:0005515=PMID:20736167, GO:0048156=PMID:20736167, GO:0005634=GO_REF:0000024, GO:0018108=PMID:9748265, GO:0043621=GO_REF:0000024, GO:0005524=GO_REF:0000037, GO:0007399=PMID:8769099, GO:0090312=GO_REF:0000019, GO:0004672=PMID:8769099, GO:0046777=GO_REF:0000024, GO:0016607=GO_REF:0000024, GO:0004674=PMID:20736167, GO:0018107=PMID:20736167, GO:0030529=GO_REF:0000019, GO:0007623=GO_REF:0000024, GO:0043518=PMID:20736167, GO:0005654=Reactome:REACT_111075, GO:0006468=GO_REF:0000024, GO:0004712=GO_REF:0000003, GO:0004713=GO_REF:0000024, GO:0000278=Reactome:REACT_152, GO:0004715=PMID:9748265} Q13627 Dual specificity tyrosine-phosphorylation-regulated kinase 1A protein 20120312 {GO:0005515=IPI, GO:0048156=ISS, GO:0005634=ISS, GO:0018108=IDA, GO:0043621=ISS, GO:0005524=IEA, GO:0007399=TAS, GO:0090312=IEA, GO:0004672=TAS, GO:0046777=ISS, GO:0016607=ISS, GO:0004674=ISS, GO:0018107=ISS, GO:0030529=IEA, GO:0007623=ISS, GO:0043518=ISS, GO:0005654=TAS, GO:0006468=ISS, GO:0004712=IEA, GO:0004713=ISS, GO:0000278=TAS, GO:0004715=IDA} circadian rhythm, mitotic cell cycle, negative regulation of DNA damage response, signal transduction by p53 class mediator, nervous system development, peptidyl-threonine phosphorylation, peptidyl-tyrosine phosphorylation, positive regulation of protein deacetylation, protein autophosphorylation, protein phosphorylation nuclear speck, nucleoplasm, nucleus, ribonucleoprotein complex ATP binding, non-membrane spanning protein tyrosine kinase activity, protein binding, protein kinase activity, protein self-association, protein serine/threonine kinase activity, protein serine/threonine/tyrosine kinase activity, protein tyrosine kinase activity, tau protein binding Human UniProtKB:Q61214 DYRK1B HPA UniProtKB {GO:0005515=PMID:14500717, GO:0004672=PMID:11980910, GO:0004674=GO_REF:0000037, GO:0003713=PMID:11980910, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0006468=PMID:11980910, GO:0004712=GO_REF:0000003, GO:0004713=GO_REF:0000037, GO:0045893=PMID:11980910, GO:0005524=GO_REF:0000037, GO:0043231=GO_REF:0000052} Q9Y463 Dual specificity tyrosine-phosphorylation-regulated kinase 1B protein 20101115 {GO:0005515=IPI, GO:0004672=IDA, GO:0004674=IEA, GO:0003713=IDA, GO:0005730=IDA, GO:0005634=IDA, GO:0006468=IDA, GO:0004712=IEA, GO:0004713=IEA, GO:0045893=IDA, GO:0005524=IEA, GO:0043231=IDA} positive regulation of transcription, DNA-dependent, protein phosphorylation intracellular membrane-bounded organelle, nucleolus, nucleus ATP binding, protein binding, protein kinase activity, protein serine/threonine kinase activity, protein serine/threonine/tyrosine kinase activity, protein tyrosine kinase activity, transcription coactivator activity Human DYRK2 HPA UniProtKB {GO:0043130=PMID:19965871, GO:0000287=PMID:9748265, GO:0030145=PMID:9748265, GO:0045725=PMID:11311121, GO:0051534=PMID:16511445, GO:0005730=GO_REF:0000052, GO:0000151=PMID:19287380, GO:0005634=GO_REF:0000052, GO:0005524=PMID:11311121, GO:0006974=PMID:19965871, GO:0043231=GO_REF:0000052, GO:0007224=PMID:18455992, GO:0042771=PMID:17349958, GO:0005737=GO_REF:0000052, GO:0004674=PMID:11311121, GO:0030529=GO_REF:0000019, GO:0004712=GO_REF:0000003, GO:0006468=PMID:11311121, GO:0004713=PMID:9748265} Q92630 Dual specificity tyrosine-phosphorylation-regulated kinase 2 protein 20101115 {GO:0043130=IDA, GO:0000287=IDA, GO:0030145=IDA, GO:0045725=IDA, GO:0051534=IMP, GO:0005730=IDA, GO:0000151=IDA, GO:0005634=IDA, GO:0005524=IDA, GO:0006974=IEP, GO:0043231=IDA, GO:0007224=IMP, GO:0042771=IDA, GO:0005737=IDA, GO:0004674=IDA, GO:0030529=IEA, GO:0004712=IEA, GO:0006468=IDA, GO:0004713=IDA} intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator, negative regulation of NFAT protein import into nucleus, positive regulation of glycogen biosynthetic process, protein phosphorylation, response to DNA damage stimulus, smoothened signaling pathway cytoplasm, intracellular membrane-bounded organelle, nucleolus, nucleus, ribonucleoprotein complex, ubiquitin ligase complex ATP binding, magnesium ion binding, manganese ion binding, protein serine/threonine kinase activity, protein serine/threonine/tyrosine kinase activity, protein tyrosine kinase activity, ubiquitin binding Human DYRK3 InterPro UniProtKB {GO:0000287=PMID:10779429, GO:0004672=GO_REF:0000002, GO:0004674=GO_REF:0000037, GO:0030218=PMID:10779429, GO:0005634=PMID:10779429, GO:0006468=PMID:10779429, GO:0004712=GO_REF:0000003, GO:0004713=GO_REF:0000037, GO:0005524=GO_REF:0000002} Q5SY34 Dual-specificity tyrosine-phosphorylation-regulated kinase 3 protein 20130413 {GO:0000287=IDA, GO:0004672=IEA, GO:0004674=IEA, GO:0030218=IDA, GO:0005634=IDA, GO:0006468=IDA, GO:0004712=IEA, GO:0004713=IEA, GO:0005524=IEA} erythrocyte differentiation, protein phosphorylation nucleus ATP binding, magnesium ion binding, protein kinase activity, protein serine/threonine kinase activity, protein serine/threonine/tyrosine kinase activity, protein tyrosine kinase activity Human InterPro:IPR000719|InterPro:IPR017441 DYRK4 HPA UniProtKB {GO:0005794=GO_REF:0000052, GO:0004674=GO_REF:0000029, GO:0016301=GO_REF:0000038, GO:0006468=GO_REF:0000029, GO:0004712=GO_REF:0000003, GO:0004713=GO_REF:0000037, GO:0005524=GO_REF:0000029, GO:0046872=GO_REF:0000037, GO:0016772=GO_REF:0000002} Q9NR20 Dual specificity tyrosine-phosphorylation-regulated kinase 4 protein 20100326 {GO:0005794=IDA, GO:0004674=NAS, GO:0016301=IEA, GO:0006468=NAS, GO:0004712=IEA, GO:0004713=IEA, GO:0005524=NAS, GO:0046872=IEA, GO:0016772=IEA} protein phosphorylation Golgi apparatus ATP binding, kinase activity, metal ion binding, protein serine/threonine kinase activity, protein serine/threonine/tyrosine kinase activity, protein tyrosine kinase activity, transferase activity, transferring phosphorus-containing groups Human DYSF PINC UniProtKB {GO:0005544=PMID:11959863, GO:0005886=PMID:10496277, GO:0030315=GO_REF:0000019, GO:0001778=GO_REF:0000019, GO:0016021=GO_REF:0000037, GO:0006906=GO_REF:0000019, GO:0030659=GO_REF:0000039, GO:0030027=GO_REF:0000019} O75923 Dysferlin protein 20030904 {GO:0005544=IMP, GO:0005886=TAS, GO:0030315=IEA, GO:0001778=IEA, GO:0016021=IEA, GO:0006906=IEA, GO:0030659=IEA, GO:0030027=IEA} plasma membrane repair, vesicle fusion T-tubule, cytoplasmic vesicle membrane, integral to membrane, lamellipodium, plasma membrane calcium-dependent phospholipid binding Human DYX1C1 IntAct UniProtKB {GO:0005515=PMID:20562859, GO:0005737=PMID:19423554, GO:0061136=PMID:19423554, GO:0030331=PMID:19423554, GO:0033146=PMID:19423554, GO:0005634=PMID:19423554, GO:0001764=GO_REF:0000024} Q8WXU2 Dyslexia susceptibility 1 candidate gene 1 protein protein 20130415 {GO:0005515=IPI, GO:0005737=IDA, GO:0061136=IDA, GO:0030331=IDA, GO:0033146=IDA, GO:0005634=IDA, GO:0001764=ISS} neuron migration, regulation of intracellular estrogen receptor signaling pathway, regulation of proteasomal protein catabolic process cytoplasm, nucleus estrogen receptor binding, protein binding Human UniProtKB:Q9H0R8 DZANK1 InterPro UniProtKB {GO:0005622=GO_REF:0000002, GO:0008270=GO_REF:0000002} Q9NVP4 Double zinc ribbon and ankyrin repeat-containing protein 1 protein 20130413 {GO:0005622=IEA, GO:0008270=IEA} intracellular zinc ion binding Human InterPro:IPR001876 DZIP1 BHF-UCL UniProtKB {GO:0005515=PMID:15081113, GO:0042384=PMID:19852954, GO:0043234=PMID:15081113, GO:0005737=PMID:15081113, GO:0005814=PMID:19852954, GO:0005634=PMID:15081113, GO:0007275=GO_REF:0000037, GO:0008270=GO_REF:0000002, GO:0007283=GO_REF:0000037, GO:0007281=PMID:15081113, GO:0036064=PMID:19852954} Q86YF9 Zinc finger protein DZIP1 protein 20120508 {GO:0005515=IPI, GO:0042384=IMP, GO:0043234=NAS, GO:0005737=IDA, GO:0005814=IDA, GO:0005634=IDA, GO:0007275=IEA, GO:0008270=IEA, GO:0007283=IEA, GO:0007281=NAS, GO:0036064=IDA} cilium assembly, germ cell development, multicellular organismal development, spermatogenesis centriole, cilium basal body, cytoplasm, nucleus, protein complex protein binding, zinc ion binding Human DZIP1L BHF-UCL UniProtKB {GO:0042384=PMID:19852954, GO:0005814=PMID:19852954, GO:0008270=GO_REF:0000002, GO:0036064=PMID:19852954} Q8IYY4 Zinc finger protein DZIP1L protein 20120508 {GO:0042384=IMP, GO:0005814=IDA, GO:0008270=IEA, GO:0036064=IDA} cilium assembly centriole, cilium basal body zinc ion binding Human DZIP3 IntAct UniProtKB {GO:0005515=PMID:21903422, GO:0000209=PMID:12538761, GO:0004842=PMID:12538761, GO:0005737=PMID:12538761, GO:0019902=PMID:19389623, GO:0003723=PMID:12538761, GO:0008270=GO_REF:0000002, GO:0031593=PMID:12538761} Q86Y13 E3 ubiquitin-protein ligase DZIP3 protein 20130415 {GO:0005515=IPI, GO:0000209=IDA, GO:0004842=IDA, GO:0005737=IDA, GO:0019902=IDA, GO:0003723=IDA, GO:0008270=IEA, GO:0031593=IDA} protein polyubiquitination cytoplasm RNA binding, phosphatase binding, polyubiquitin binding, protein binding, ubiquitin-protein ligase activity, zinc ion binding Human UniProtKB:Q9H0E2 E2F1 BHF-UCL UniProtKB {GO:0005515=PMID:20224733, GO:0003700=PMID:11418595, GO:0008283=PMID:10199402, GO:0005634=PMID:12717439, GO:0048146=PMID:20224733, GO:0007283=GO_REF:0000019, GO:2000045=PMID:20224733, GO:0071398=GO_REF:0000019, GO:0000085=Reactome:REACT_1915, GO:0005737=GO_REF:0000019, GO:0000082=Reactome:REACT_1783, GO:0045944=PMID:20224733, GO:0035189=PMID:20224733, GO:0048255=PMID:15766563, GO:0000080=Reactome:REACT_1590, GO:0006355=PMID:12717439, GO:0003714=PMID:10199402, GO:0071456=GO_REF:0000019, GO:0006915=PMID:12717439, GO:0001047=PMID:15735762, GO:0000122=PMID:20224733, GO:0003677=PMID:15073182, GO:0071930=PMID:20224733, GO:0006351=GO_REF:0000037, GO:0043565=GO_REF:0000019, GO:0010628=PMID:15766563, GO:0005654=Reactome:REACT_111167, GO:0030900=GO_REF:0000019, GO:0000077=PMID:12717439, GO:0045893=PMID:20224733, GO:0000278=Reactome:REACT_152, GO:0045892=PMID:20224733, GO:0008134=PMID:16360038} Q01094 Transcription factor E2F1 protein 20110314 {GO:0005515=IPI, GO:0003700=TAS, GO:0008283=TAS, GO:0005634=IDA, GO:0048146=IMP, GO:0007283=IEA, GO:2000045=IMP, GO:0071398=IEA, GO:0000085=TAS, GO:0005737=IEA, GO:0000082=TAS, GO:0045944=IMP, GO:0035189=IDA, GO:0048255=IDA, GO:0000080=TAS, GO:0006355=IDA, GO:0003714=TAS, GO:0071456=IEA, GO:0006915=IMP, GO:0001047=IDA, GO:0000122=IMP, GO:0003677=IDA, GO:0071930=IMP, GO:0006351=IEA, GO:0043565=IEA, GO:0010628=IDA, GO:0005654=TAS, GO:0030900=IEA, GO:0000077=IMP, GO:0045893=IMP, GO:0000278=TAS, GO:0045892=IMP, GO:0008134=IPI} DNA damage checkpoint, G1 phase of mitotic cell cycle, G1/S transition of mitotic cell cycle, G2 phase of mitotic cell cycle, apoptotic process, cell proliferation, cellular response to fatty acid, cellular response to hypoxia, forebrain development, mRNA stabilization, mitotic cell cycle, negative regulation of transcription from RNA polymerase II promoter, negative regulation of transcription involved in G1/S phase of mitotic cell cycle, negative regulation of transcription, DNA-dependent, positive regulation of fibroblast proliferation, positive regulation of gene expression, positive regulation of transcription from RNA polymerase II promoter, positive regulation of transcription, DNA-dependent, regulation of G1/S transition of mitotic cell cycle, regulation of transcription, DNA-dependent, spermatogenesis, transcription, DNA-dependent Rb-E2F complex, cytoplasm, nucleoplasm, nucleus DNA binding, core promoter binding, protein binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, transcription corepressor activity, transcription factor binding Human E2F2 Reactome UniProtKB {GO:0005515=PMID:16360038, GO:0005667=GO_REF:0000002, GO:0006367=PMID:8246996, GO:0003700=GO_REF:0000019, GO:0051726=GO_REF:0000019, GO:0006915=GO_REF:0000019, GO:0005654=Reactome:REACT_1882, GO:0001047=PMID:15735762, GO:0000278=Reactome:REACT_152, GO:0000080=Reactome:REACT_1590, GO:0003677=PMID:8246995, GO:0008134=PMID:16360038} Q14209 Transcription factor E2F2 protein 20130213 {GO:0005515=IPI, GO:0005667=IEA, GO:0006367=TAS, GO:0003700=IEA, GO:0051726=IEA, GO:0006915=IEA, GO:0005654=TAS, GO:0001047=IDA, GO:0000278=TAS, GO:0000080=TAS, GO:0003677=TAS, GO:0008134=IPI} G1 phase of mitotic cell cycle, apoptotic process, mitotic cell cycle, regulation of cell cycle, transcription initiation from RNA polymerase II promoter nucleoplasm, transcription factor complex DNA binding, core promoter binding, protein binding, sequence-specific DNA binding transcription factor activity, transcription factor binding Human E2F3 Reactome UniProtKB {GO:0005515=PMID:17438371, GO:0000085=Reactome:REACT_1915, GO:0005667=GO_REF:0000002, GO:0008284=GO_REF:0000019, GO:0006367=PMID:8246996, GO:0003700=GO_REF:0000019, GO:0005654=Reactome:REACT_9023, GO:0001047=PMID:15735762, GO:0000278=Reactome:REACT_152, GO:0000080=Reactome:REACT_1590, GO:0045893=GO_REF:0000019} O00716 Transcription factor E2F3 protein 20130213 {GO:0005515=IPI, GO:0000085=TAS, GO:0005667=IEA, GO:0008284=IEA, GO:0006367=TAS, GO:0003700=IEA, GO:0005654=TAS, GO:0001047=IDA, GO:0000278=TAS, GO:0000080=TAS, GO:0045893=IEA} G1 phase of mitotic cell cycle, G2 phase of mitotic cell cycle, mitotic cell cycle, positive regulation of cell proliferation, positive regulation of transcription, DNA-dependent, transcription initiation from RNA polymerase II promoter nucleoplasm, transcription factor complex core promoter binding, protein binding, sequence-specific DNA binding transcription factor activity Human E2F4 Reactome UniProtKB {GO:0005515=PMID:22002537, GO:0010467=Reactome:REACT_71, GO:0005667=GO_REF:0000002, GO:0008361=GO_REF:0000019, GO:0006367=Reactome:REACT_12627, GO:0003700=PMID:11418595, GO:0008015=GO_REF:0000019, GO:0019904=PMID:16360038, GO:0003677=PMID:11418595, GO:0006351=Reactome:REACT_121061, GO:0006884=GO_REF:0000019, GO:0042384=GO_REF:0000019, GO:0000083=GO_REF:0000019, GO:0045944=Reactome:REACT_120734, GO:0042127=GO_REF:0000019, GO:0002064=GO_REF:0000019, GO:0009887=GO_REF:0000019, GO:0007179=Reactome:REACT_6844, GO:0005654=Reactome:REACT_121097, GO:0000278=Reactome:REACT_152, GO:0000080=Reactome:REACT_1590, GO:0008134=PMID:16360038} Q16254 Transcription factor E2F4 protein 20130301 {GO:0005515=IPI, GO:0010467=TAS, GO:0005667=IEA, GO:0008361=IEA, GO:0006367=TAS, GO:0003700=IDA, GO:0008015=IEA, GO:0019904=IPI, GO:0003677=IMP, GO:0006351=TAS, GO:0006884=IEA, GO:0042384=IEA, GO:0000083=IEA, GO:0045944=TAS, GO:0042127=IEA, GO:0002064=IEA, GO:0009887=IEA, GO:0007179=TAS, GO:0005654=TAS, GO:0000278=TAS, GO:0000080=TAS, GO:0008134=IPI} G1 phase of mitotic cell cycle, blood circulation, cell volume homeostasis, cilium assembly, epithelial cell development, gene expression, mitotic cell cycle, organ morphogenesis, positive regulation of transcription from RNA polymerase II promoter, regulation of cell proliferation, regulation of cell size, regulation of transcription involved in G1/S phase of mitotic cell cycle, transcription initiation from RNA polymerase II promoter, transcription, DNA-dependent, transforming growth factor beta receptor signaling pathway nucleoplasm, transcription factor complex DNA binding, protein binding, protein domain specific binding, sequence-specific DNA binding transcription factor activity, transcription factor binding Human E2F5 Reactome UniProtKB {GO:0005515=PMID:16360038, GO:0010467=Reactome:REACT_71, GO:0005667=GO_REF:0000002, GO:0003700=GO_REF:0000019, GO:0006367=Reactome:REACT_12627, GO:0003677=GO_REF:0000037, GO:0006351=Reactome:REACT_121061, GO:0005737=GO_REF:0000019, GO:0045944=Reactome:REACT_120734, GO:0009887=GO_REF:0000019, GO:0005654=Reactome:REACT_121097, GO:0007179=Reactome:REACT_6844, GO:0000080=Reactome:REACT_1590, GO:0000278=Reactome:REACT_152, GO:0008134=PMID:16360038} Q15329 Transcription factor E2F5 protein 20130301 {GO:0005515=IPI, GO:0010467=TAS, GO:0005667=IEA, GO:0003700=IEA, GO:0006367=TAS, GO:0003677=IEA, GO:0006351=TAS, GO:0005737=IEA, GO:0045944=TAS, GO:0009887=IEA, GO:0005654=TAS, GO:0007179=TAS, GO:0000080=TAS, GO:0000278=TAS, GO:0008134=IPI} G1 phase of mitotic cell cycle, gene expression, mitotic cell cycle, organ morphogenesis, positive regulation of transcription from RNA polymerase II promoter, transcription initiation from RNA polymerase II promoter, transcription, DNA-dependent, transforming growth factor beta receptor signaling pathway cytoplasm, nucleoplasm, transcription factor complex DNA binding, protein binding, sequence-specific DNA binding transcription factor activity, transcription factor binding Human E2F6 PINC UniProtKB {GO:0005667=GO_REF:0000002, GO:0000083=GO_REF:0000019, GO:0003700=GO_REF:0000019, GO:0003714=PMID:9501179, GO:0071339=PMID:15960975, GO:0000122=PMID:9501179, GO:0003677=GO_REF:0000019, GO:0006351=GO_REF:0000037} O75461 Transcription factor E2F6 protein 20030904 {GO:0005667=IEA, GO:0000083=IEA, GO:0003700=IEA, GO:0003714=TAS, GO:0071339=IDA, GO:0000122=TAS, GO:0003677=IEA, GO:0006351=IEA} negative regulation of transcription from RNA polymerase II promoter, regulation of transcription involved in G1/S phase of mitotic cell cycle, transcription, DNA-dependent MLL1 complex, transcription factor complex DNA binding, sequence-specific DNA binding transcription factor activity, transcription corepressor activity Human E2F7 IntAct UniProtKB {GO:0005667=GO_REF:0000002, GO:0032466=GO_REF:0000024, GO:0003700=PMID:22802528, GO:0008285=PMID:22802528, GO:0030330=PMID:22802528, GO:0003714=GO_REF:0000024, GO:0060707=GO_REF:0000024, GO:0032877=GO_REF:0000024, GO:2000134=GO_REF:0000024, GO:0005634=GO_REF:0000019, GO:0002040=PMID:22903062, GO:0001047=PMID:22903062, GO:0000122=PMID:22802528, GO:0001890=GO_REF:0000024, GO:0003677=GO_REF:0000038, GO:0006351=GO_REF:0000037, GO:0071930=PMID:22802528, GO:0042802=PMID:15133492, GO:0045944=PMID:22903062, GO:0060718=GO_REF:0000024, GO:0070365=GO_REF:0000024} Q96AV8 Transcription factor E2F7 protein 20130415 {GO:0005667=IEA, GO:0032466=ISS, GO:0003700=IDA, GO:0008285=IMP, GO:0030330=IDA, GO:0003714=ISS, GO:0060707=ISS, GO:0032877=ISS, GO:2000134=ISS, GO:0005634=IEA, GO:0002040=IMP, GO:0001047=IDA, GO:0000122=IDA, GO:0001890=ISS, GO:0003677=IEA, GO:0006351=IEA, GO:0071930=IDA, GO:0042802=IPI, GO:0045944=IMP, GO:0060718=ISS, GO:0070365=ISS} DNA damage response, signal transduction by p53 class mediator, chorionic trophoblast cell differentiation, hepatocyte differentiation, negative regulation of G1/S transition of mitotic cell cycle, negative regulation of cell proliferation, negative regulation of cytokinesis, negative regulation of transcription from RNA polymerase II promoter, negative regulation of transcription involved in G1/S phase of mitotic cell cycle, placenta development, positive regulation of DNA endoreduplication, positive regulation of transcription from RNA polymerase II promoter, sprouting angiogenesis, transcription, DNA-dependent, trophoblast giant cell differentiation nucleus, transcription factor complex DNA binding, core promoter binding, identical protein binding, sequence-specific DNA binding transcription factor activity, transcription corepressor activity Human UniProtKB:Q96AV8 E2F8 UniProtKB UniProtKB {GO:0005667=GO_REF:0000002, GO:0032466=GO_REF:0000024, GO:0003700=GO_REF:0000002, GO:0008283=GO_REF:0000019, GO:0003714=GO_REF:0000024, GO:0060707=GO_REF:0000024, GO:0032877=GO_REF:0000024, GO:0005634=GO_REF:0000019, GO:0001047=PMID:22903062, GO:0002040=PMID:22903062, GO:0000122=GO_REF:0000024, GO:0001890=GO_REF:0000024, GO:0003677=GO_REF:0000038, GO:0006351=GO_REF:0000038, GO:0042803=GO_REF:0000019, GO:0045944=PMID:22903062, GO:0033301=GO_REF:0000024, GO:0060718=GO_REF:0000024, GO:0070365=GO_REF:0000024} E9PP48 Transcription factor E2F8 protein 20130413 {GO:0005667=IEA, GO:0032466=ISS, GO:0003700=IEA, GO:0008283=IEA, GO:0003714=ISS, GO:0060707=ISS, GO:0032877=ISS, GO:0005634=IEA, GO:0001047=IDA, GO:0002040=IMP, GO:0000122=ISS, GO:0001890=ISS, GO:0003677=IEA, GO:0006351=IEA, GO:0042803=IEA, GO:0045944=IMP, GO:0033301=ISS, GO:0060718=ISS, GO:0070365=ISS} cell cycle comprising mitosis without cytokinesis, cell proliferation, chorionic trophoblast cell differentiation, hepatocyte differentiation, negative regulation of cytokinesis, negative regulation of transcription from RNA polymerase II promoter, placenta development, positive regulation of DNA endoreduplication, positive regulation of transcription from RNA polymerase II promoter, sprouting angiogenesis, transcription, DNA-dependent, trophoblast giant cell differentiation nucleus, transcription factor complex DNA binding, core promoter binding, protein homodimerization activity, sequence-specific DNA binding transcription factor activity, transcription corepressor activity Human UniProtKB-KW:KW-0804 E4F1 IntAct UniProtKB {GO:0005515=PMID:14729613, GO:0016567=GO_REF:0000041, GO:0003700=PMID:9121437, GO:0035497=PMID:14645522, GO:0008283=PMID:10869426, GO:0016874=GO_REF:0000037, GO:0009790=GO_REF:0000019, GO:0010564=PMID:14645522, GO:0009794=GO_REF:0000019, GO:0005737=GO_REF:0000039, GO:0003714=PMID:10869426, GO:0003713=PMID:9121437, GO:0005819=GO_REF:0000019, GO:0000122=PMID:14645522, GO:0003676=GO_REF:0000002, GO:0003677=PMID:10869426, GO:0006351=GO_REF:0000037, GO:0006260=GO_REF:0000019, GO:0071850=PMID:14645522, GO:0007067=GO_REF:0000037, GO:0019048=GO_REF:0000037, GO:0005654=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0040008=GO_REF:0000037, GO:0051301=GO_REF:0000037} Q66K89 Transcription factor E4F1 protein 20130415 {GO:0005515=IPI, GO:0016567=IEA, GO:0003700=TAS, GO:0035497=IDA, GO:0008283=TAS, GO:0016874=IEA, GO:0009790=IEA, GO:0010564=IDA, GO:0009794=IEA, GO:0005737=IEA, GO:0003714=TAS, GO:0003713=TAS, GO:0005819=IEA, GO:0000122=IDA, GO:0003676=IEA, GO:0003677=TAS, GO:0006351=IEA, GO:0006260=IEA, GO:0071850=TAS, GO:0007067=IEA, GO:0019048=IEA, GO:0005654=IEA, GO:0008270=IEA, GO:0040008=IEA, GO:0051301=IEA} DNA replication, cell division, cell proliferation, embryo development, mitosis, mitotic cell cycle arrest, negative regulation of transcription from RNA polymerase II promoter, protein ubiquitination, regulation of cell cycle process, regulation of growth, regulation of mitotic cell cycle, embryonic, transcription, DNA-dependent, virus-host interaction cytoplasm, nucleoplasm, spindle DNA binding, cAMP response element binding, ligase activity, nucleic acid binding, protein binding, sequence-specific DNA binding transcription factor activity, transcription coactivator activity, transcription corepressor activity, zinc ion binding Human UniProtKB:Q9NS23-2 EAF1 IntAct UniProtKB {GO:0005515=PMID:21729782, GO:0006355=GO_REF:0000037, GO:0015030=GO_REF:0000039, GO:0016607=GO_REF:0000039, GO:0032783=GO_REF:0000002, GO:0006351=GO_REF:0000037} Q96JC9 ELL-associated factor 1 protein 20130415 {GO:0005515=IPI, GO:0006355=IEA, GO:0015030=IEA, GO:0016607=IEA, GO:0032783=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent Cajal body, ELL-EAF complex, nuclear speck protein binding Human UniProtKB:O95402 EAF2 HPA UniProtKB {GO:0005515=PMID:17395368, GO:0060770=GO_REF:0000019, GO:0030308=GO_REF:0000019, GO:0006355=GO_REF:0000002, GO:0016607=GO_REF:0000039, GO:0032783=GO_REF:0000002, GO:0005730=GO_REF:0000052, GO:0006915=GO_REF:0000037, GO:0005634=GO_REF:0000052, GO:0006917=GO_REF:0000019, GO:0045893=GO_REF:0000019, GO:0006351=GO_REF:0000037} Q96CJ1 ELL-associated factor 2 protein 20100326 {GO:0005515=IPI, GO:0060770=IEA, GO:0030308=IEA, GO:0006355=IEA, GO:0016607=IEA, GO:0032783=IEA, GO:0005730=IDA, GO:0006915=IEA, GO:0005634=IDA, GO:0006917=IEA, GO:0045893=IEA, GO:0006351=IEA} apoptotic process, induction of apoptosis, negative regulation of cell growth, negative regulation of epithelial cell proliferation involved in prostate gland development, positive regulation of transcription, DNA-dependent, regulation of transcription, DNA-dependent, transcription, DNA-dependent ELL-EAF complex, nuclear speck, nucleolus, nucleus protein binding NOT Human EAPP HPA UniProtKB {GO:0008284=PMID:15716352, GO:0005737=GO_REF:0000052, GO:0005794=GO_REF:0000052, GO:0032968=PMID:15716352, GO:0005634=GO_REF:0000052, GO:0034244=PMID:15716352} Q56P03 E2F-associated phosphoprotein protein 20110516 {GO:0008284=IDA, GO:0005737=IDA, GO:0005794=IDA, GO:0032968=IDA, GO:0005634=IDA, GO:0034244=IDA} negative regulation of transcription elongation from RNA polymerase II promoter, positive regulation of cell proliferation, positive regulation of transcription elongation from RNA polymerase II promoter Golgi apparatus, cytoplasm, nucleus Human EARS2 Reactome UniProtKB {GO:0005739=PMID:19805282, GO:0010467=Reactome:REACT_71, GO:0050561=PMID:19805282, GO:0005737=GO_REF:0000002, GO:0070127=PMID:19805282, GO:0006424=PMID:19805282, GO:0000049=GO_REF:0000002, GO:0004818=PMID:19805282, GO:0005759=GO_REF:0000039, GO:0005524=GO_REF:0000037, GO:0006418=Reactome:REACT_15482} Q5JPH6 Probable glutamate--tRNA ligase, mitochondrial protein 20130301 {GO:0005739=IDA, GO:0010467=TAS, GO:0050561=IDA, GO:0005737=IEA, GO:0070127=IDA, GO:0006424=IDA, GO:0000049=IEA, GO:0004818=IDA, GO:0005759=IEA, GO:0005524=IEA, GO:0006418=TAS} gene expression, glutamyl-tRNA aminoacylation, tRNA aminoacylation for mitochondrial protein translation, tRNA aminoacylation for protein translation cytoplasm, mitochondrial matrix, mitochondrion ATP binding, glutamate-tRNA ligase activity, glutamate-tRNA(Gln) ligase activity, tRNA binding Human EBAG9 HPA UniProtKB {GO:0016505=PMID:10426319, GO:0005794=GO_REF:0000052, GO:0000139=GO_REF:0000039, GO:0005886=GO_REF:0000052, GO:0006915=GO_REF:0000037, GO:0016021=GO_REF:0000029, GO:0030141=GO_REF:0000019, GO:0001558=PMID:10426319, GO:0005925=GO_REF:0000052} O00559 Receptor-binding cancer antigen expressed on SiSo cells protein 20101115 {GO:0016505=NAS, GO:0005794=IDA, GO:0000139=IEA, GO:0005886=IDA, GO:0006915=IEA, GO:0016021=NAS, GO:0030141=IEA, GO:0001558=NAS, GO:0005925=IDA} apoptotic process, regulation of cell growth Golgi apparatus, Golgi membrane, focal adhesion, integral to membrane, plasma membrane, secretory granule apoptotic protease activator activity Human EBF1 UniProtKB UniProtKB {GO:0006355=GO_REF:0000038, GO:0003700=GO_REF:0000019, GO:0046983=GO_REF:0000002, GO:0005634=GO_REF:0000039, GO:0007275=GO_REF:0000037, GO:0045893=GO_REF:0000019, GO:0003677=GO_REF:0000019, GO:0046872=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q9UH73 Transcription factor COE1 protein 20130413 {GO:0006355=IEA, GO:0003700=IEA, GO:0046983=IEA, GO:0005634=IEA, GO:0007275=IEA, GO:0045893=IEA, GO:0003677=IEA, GO:0046872=IEA, GO:0006351=IEA} multicellular organismal development, positive regulation of transcription, DNA-dependent, regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus DNA binding, metal ion binding, protein dimerization activity, sequence-specific DNA binding transcription factor activity Human UniProtKB-SubCell:SL-0191 EBF2 UniProtKB UniProtKB {GO:0006355=GO_REF:0000002, GO:0046983=GO_REF:0000002, GO:0005634=GO_REF:0000039, GO:0007275=GO_REF:0000037, GO:0045893=GO_REF:0000019, GO:0003677=GO_REF:0000019, GO:0046872=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q9HAK2 Transcription factor COE2 protein 20130413 {GO:0006355=IEA, GO:0046983=IEA, GO:0005634=IEA, GO:0007275=IEA, GO:0045893=IEA, GO:0003677=IEA, GO:0046872=IEA, GO:0006351=IEA} multicellular organismal development, positive regulation of transcription, DNA-dependent, regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus DNA binding, metal ion binding, protein dimerization activity Human UniProtKB-SubCell:SL-0191 EBF3 UniProtKB UniProtKB {GO:0006355=GO_REF:0000002, GO:0046983=GO_REF:0000002, GO:0005634=GO_REF:0000039, GO:0007275=GO_REF:0000037, GO:0045893=GO_REF:0000019, GO:0003677=GO_REF:0000037, GO:0046872=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q9H4W6 Transcription factor COE3 protein 20130413 {GO:0006355=IEA, GO:0046983=IEA, GO:0005634=IEA, GO:0007275=IEA, GO:0045893=IEA, GO:0003677=IEA, GO:0046872=IEA, GO:0006351=IEA} multicellular organismal development, positive regulation of transcription, DNA-dependent, regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus DNA binding, metal ion binding, protein dimerization activity Human UniProtKB-SubCell:SL-0191 EBF4 UniProtKB UniProtKB {GO:0006355=GO_REF:0000037, GO:0046983=GO_REF:0000002, GO:0005634=GO_REF:0000039, GO:0007275=GO_REF:0000037, GO:0003677=GO_REF:0000037, GO:0046872=GO_REF:0000037, GO:0006351=GO_REF:0000037, GO:0008134=GO_REF:0000019} Q9BQW3 Transcription factor COE4 protein 20130413 {GO:0006355=IEA, GO:0046983=IEA, GO:0005634=IEA, GO:0007275=IEA, GO:0003677=IEA, GO:0046872=IEA, GO:0006351=IEA, GO:0008134=IEA} multicellular organismal development, regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus DNA binding, metal ion binding, protein dimerization activity, transcription factor binding Human UniProtKB-SubCell:SL-0191 EBI3 GOC UniProtKB {GO:0004896=PMID:9342359, GO:0005886=PMID:8551575, GO:0006959=PMID:8551575, GO:0045078=PMID:14743498, GO:0019221=PMID:9342359, GO:0046641=PMID:14743498, GO:0045523=GO_REF:0000019, GO:0042088=PMID:14743498, GO:0005615=GO_REF:0000037, GO:0005125=GO_REF:0000037} Q14213 Interleukin-27 subunit beta protein 20130413 {GO:0004896=IPI, GO:0005886=TAS, GO:0006959=TAS, GO:0045078=TAS, GO:0019221=IPI, GO:0046641=TAS, GO:0045523=IEA, GO:0042088=TAS, GO:0005615=IEA, GO:0005125=IEA} T-helper 1 type immune response, cytokine-mediated signaling pathway, humoral immune response, positive regulation of alpha-beta T cell proliferation, positive regulation of interferon-gamma biosynthetic process extracellular space, plasma membrane cytokine activity, cytokine receptor activity, interleukin-27 receptor binding Human UniProtKB:P29459 EBLN2 null null {} null null null null {} null null null EBNA1BP2 HPA UniProtKB {GO:0016020=PMID:7596406, GO:0042254=GO_REF:0000037, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052} Q99848 Probable rRNA-processing protein EBP2 protein 20101115 {GO:0016020=TAS, GO:0042254=IEA, GO:0005730=IDA, GO:0005634=IDA} ribosome biogenesis membrane, nucleolus, nucleus Human EBP GOC UniProtKB {GO:0030097=GO_REF:0000019, GO:0006695=Reactome:REACT_9405, GO:0004769=PMID:10391219, GO:0000247=GO_REF:0000019, GO:0005783=GO_REF:0000052, GO:0044281=Reactome:REACT_111217, GO:0047750=GO_REF:0000003, GO:0001501=PMID:10391219, GO:0005887=PMID:7706302, GO:0006855=PMID:7706302, GO:0005789=Reactome:REACT_9999, GO:0016126=GO_REF:0000019, GO:0016021=GO_REF:0000002, GO:0015238=PMID:7706302, GO:0004888=PMID:7706302, GO:0008203=PMID:10391219} Q15125 3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase protein 20130413 {GO:0030097=IEA, GO:0006695=TAS, GO:0004769=TAS, GO:0000247=IEA, GO:0005783=IDA, GO:0044281=TAS, GO:0047750=IEA, GO:0001501=TAS, GO:0005887=TAS, GO:0006855=TAS, GO:0005789=TAS, GO:0016126=IEA, GO:0016021=IEA, GO:0015238=TAS, GO:0004888=TAS, GO:0008203=TAS} cholesterol biosynthetic process, cholesterol metabolic process, drug transmembrane transport, hemopoiesis, skeletal system development, small molecule metabolic process, sterol biosynthetic process endoplasmic reticulum, endoplasmic reticulum membrane, integral to membrane, integral to plasma membrane C-8 sterol isomerase activity, cholestenol delta-isomerase activity, drug transmembrane transporter activity, steroid delta-isomerase activity, transmembrane signaling receptor activity Human EBPL UniProtKB UniProtKB {GO:0005783=GO_REF:0000002, GO:0005789=GO_REF:0000039, GO:0016125=GO_REF:0000002, GO:0016021=GO_REF:0000037, GO:0047750=GO_REF:0000002} Q9BY08 Emopamil-binding protein-like protein 20130413 {GO:0005783=IEA, GO:0005789=IEA, GO:0016125=IEA, GO:0016021=IEA, GO:0047750=IEA} sterol metabolic process endoplasmic reticulum, endoplasmic reticulum membrane, integral to membrane cholestenol delta-isomerase activity Human UniProtKB-SubCell:SL-0097 ECD PINC UniProtKB {GO:0006110=PMID:9928932, GO:0005737=GO_REF:0000039, GO:0006355=GO_REF:0000037, GO:0006366=PMID:9928932, GO:0008283=GO_REF:0000019, GO:0003713=PMID:9928932, GO:0005634=GO_REF:0000039, GO:2000045=GO_REF:0000019} O95905 Protein SGT1 protein 20030904 {GO:0006110=TAS, GO:0005737=IEA, GO:0006355=IEA, GO:0006366=TAS, GO:0008283=IEA, GO:0003713=TAS, GO:0005634=IEA, GO:2000045=IEA} cell proliferation, regulation of G1/S transition of mitotic cell cycle, regulation of glycolysis, regulation of transcription, DNA-dependent, transcription from RNA polymerase II promoter cytoplasm, nucleus transcription coactivator activity Human ECE1 BHF-UCL UniProtKB {GO:0048471=PMID:9710124, GO:0034959=PMID:7805846, GO:0010814=PMID:18039931, GO:0010815=PMID:18039931, GO:0010816=PMID:18039931, GO:0042803=PMID:7805846, GO:0046872=GO_REF:0000037, GO:0043583=PMID:9915973, GO:0019229=PMID:7805846, GO:0007507=PMID:9915973, GO:0016486=PMID:7864876, GO:0016485=PMID:7805846, GO:0006508=GO_REF:0000037, GO:0001921=PMID:18039931, GO:0003100=PMID:7805846, GO:0033093=PMID:9710124, GO:0031982=PMID:9449382, GO:0060037=GO_REF:0000019, GO:0004175=PMID:18039931, GO:0031302=PMID:18039931, GO:0042447=PMID:7864876, GO:0016021=PMID:7805846, GO:0017046=PMID:7864876, GO:0004222=PMID:8062389, GO:0009897=PMID:9449382, GO:0042733=PMID:9915973, GO:0005768=PMID:18039931} P42892 Endothelin-converting enzyme 1 protein 20080903 {GO:0048471=IDA, GO:0034959=IDA, GO:0010814=IDA, GO:0010815=IDA, GO:0010816=IDA, GO:0042803=IPI, GO:0046872=IEA, GO:0043583=IMP, GO:0019229=IC, GO:0007507=IMP, GO:0016486=IDA, GO:0016485=IDA, GO:0006508=IEA, GO:0001921=IMP, GO:0003100=IC, GO:0033093=IDA, GO:0031982=ISS, GO:0060037=IEA, GO:0004175=IDA, GO:0031302=TAS, GO:0042447=IDA, GO:0016021=IDA, GO:0017046=IC, GO:0004222=ISS, GO:0009897=IDA, GO:0042733=IMP, GO:0005768=IDA} bradykinin catabolic process, calcitonin catabolic process, ear development, embryonic digit morphogenesis, endothelin maturation, heart development, hormone catabolic process, peptide hormone processing, pharyngeal system development, positive regulation of receptor recycling, protein processing, proteolysis, regulation of systemic arterial blood pressure by endothelin, regulation of vasoconstriction, substance P catabolic process Weibel-Palade body, endosome, external side of plasma membrane, integral to membrane, intrinsic to endosome membrane, perinuclear region of cytoplasm, vesicle endopeptidase activity, metal ion binding, metalloendopeptidase activity, peptide hormone binding, protein homodimerization activity Human UniProtKB:P42893 ECE2 UniProtKB UniProtKB {GO:0007507=GO_REF:0000024, GO:0016486=PMID:11718899, GO:0000139=GO_REF:0000039, GO:0007420=GO_REF:0000024, GO:0008168=GO_REF:0000037, GO:0007267=PMID:11718899, GO:0010002=GO_REF:0000024, GO:0006508=GO_REF:0000037, GO:0016021=GO_REF:0000037, GO:0004222=PMID:11718899, GO:0030659=PMID:11718899, GO:0046872=GO_REF:0000037} O60344 Endothelin-converting enzyme 2 protein 20030818 {GO:0007507=ISS, GO:0016486=IDA, GO:0000139=IEA, GO:0007420=ISS, GO:0008168=IEA, GO:0007267=TAS, GO:0010002=ISS, GO:0006508=IEA, GO:0016021=IEA, GO:0004222=IDA, GO:0030659=IDA, GO:0046872=IEA} brain development, cardioblast differentiation, cell-cell signaling, heart development, peptide hormone processing, proteolysis Golgi membrane, cytoplasmic vesicle membrane, integral to membrane metal ion binding, metalloendopeptidase activity, methyltransferase activity Human ECEL1 PINC UniProtKB {GO:0007218=PMID:9931490, GO:0005887=PMID:9931490, GO:0006508=GO_REF:0000037, GO:0004222=GO_REF:0000019, GO:0008237=PMID:9931490, GO:0046872=GO_REF:0000037} O95672 Endothelin-converting enzyme-like 1 protein 20030904 {GO:0007218=TAS, GO:0005887=TAS, GO:0006508=IEA, GO:0004222=IEA, GO:0008237=TAS, GO:0046872=IEA} neuropeptide signaling pathway, proteolysis integral to plasma membrane metal ion binding, metalloendopeptidase activity, metallopeptidase activity Human ECH1 HPA UniProtKB {GO:0005739=GO_REF:0000052, GO:0005515=PMID:21988832, GO:0006635=GO_REF:0000041, GO:0005102=PMID:20178365, GO:0016853=GO_REF:0000037, GO:0003824=GO_REF:0000002, GO:0005777=PMID:7558027} Q13011 Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial protein 20101115 {GO:0005739=IDA, GO:0005515=IPI, GO:0006635=IEA, GO:0005102=IPI, GO:0016853=IEA, GO:0003824=IEA, GO:0005777=NAS} fatty acid beta-oxidation mitochondrion, peroxisome catalytic activity, isomerase activity, protein binding, receptor binding Human ECHDC1 UniProtKB UniProtKB {GO:0016831=GO_REF:0000024, GO:0004492=GO_REF:0000003, GO:0003824=GO_REF:0000002, GO:0005829=GO_REF:0000024} Q9NTX5 Ethylmalonyl-CoA decarboxylase protein 20120127 {GO:0016831=ISS, GO:0004492=IEA, GO:0003824=IEA, GO:0005829=ISS} cytosol carboxy-lyase activity, catalytic activity, methylmalonyl-CoA decarboxylase activity Human UniProtKB:Q9D9V3 ECHDC2 UniProtKB UniProtKB {GO:0005739=GO_REF:0000039, GO:0006631=GO_REF:0000037, GO:0003824=GO_REF:0000002, GO:0016829=GO_REF:0000037} Q86YB7 Enoyl-CoA hydratase domain-containing protein 2, mitochondrial protein 20130413 {GO:0005739=IEA, GO:0006631=IEA, GO:0003824=IEA, GO:0016829=IEA} fatty acid metabolic process mitochondrion catalytic activity, lyase activity Human UniProtKB-SubCell:SL-0173 ECHS1 HPA UniProtKB {GO:0005515=PMID:14557246, GO:0005739=GO_REF:0000052, GO:0006635=Reactome:REACT_1473, GO:0005759=Reactome:REACT_583, GO:0044281=Reactome:REACT_111217, GO:0004300=Reactome:REACT_583, GO:0044255=Reactome:REACT_22279} P30084 Enoyl-CoA hydratase, mitochondrial protein 20100326 {GO:0005515=IPI, GO:0005739=IDA, GO:0006635=TAS, GO:0005759=TAS, GO:0044281=TAS, GO:0004300=TAS, GO:0044255=TAS} cellular lipid metabolic process, fatty acid beta-oxidation, small molecule metabolic process mitochondrial matrix, mitochondrion enoyl-CoA hydratase activity, protein binding Human ECI1 Reactome UniProtKB {GO:0016860=Reactome:REACT_1445, GO:0006635=Reactome:REACT_1473, GO:0004165=Reactome:REACT_588, GO:0005759=Reactome:REACT_1445, GO:0005743=GO_REF:0000019, GO:0044281=Reactome:REACT_111217, GO:0003824=GO_REF:0000002, GO:0044255=Reactome:REACT_22279} P42126 Enoyl-CoA delta isomerase 1, mitochondrial protein 20130213 {GO:0016860=TAS, GO:0006635=TAS, GO:0004165=TAS, GO:0005759=TAS, GO:0005743=IEA, GO:0044281=TAS, GO:0003824=IEA, GO:0044255=TAS} cellular lipid metabolic process, fatty acid beta-oxidation, small molecule metabolic process mitochondrial inner membrane, mitochondrial matrix catalytic activity, dodecenoyl-CoA delta-isomerase activity, intramolecular oxidoreductase activity Human ECI2 HPA UniProtKB {GO:0005739=GO_REF:0000054, GO:0005782=GO_REF:0000039, GO:0004165=GO_REF:0000003, GO:0005102=PMID:20178365, GO:0003824=GO_REF:0000002, GO:0000062=GO_REF:0000002, GO:0043231=GO_REF:0000052} O75521 Enoyl-CoA delta isomerase 2, mitochondrial protein 20100326 {GO:0005739=IDA, GO:0005782=IEA, GO:0004165=IEA, GO:0005102=IPI, GO:0003824=IEA, GO:0000062=IEA, GO:0043231=IDA} intracellular membrane-bounded organelle, mitochondrion, peroxisomal matrix catalytic activity, dodecenoyl-CoA delta-isomerase activity, fatty-acyl-CoA binding, receptor binding Human ECM1 GOC UniProtKB {GO:0005515=PMID:19275936, GO:2000404=GO_REF:0000019, GO:0005134=GO_REF:0000019, GO:0006357=GO_REF:0000019, GO:0010466=PMID:16512877, GO:0005578=PMID:9367673, GO:0001525=GO_REF:0000037, GO:0030502=PMID:11165938, GO:0002020=PMID:16512877, GO:0008022=PMID:12604605, GO:0031214=GO_REF:0000037, GO:0005615=GO_REF:0000019, GO:0045766=PMID:11292659, GO:0031012=PMID:20870722, GO:0007165=PMID:12761501, GO:0006954=GO_REF:0000019, GO:0001960=GO_REF:0000019, GO:0001938=PMID:11292659, GO:0001503=GO_REF:0000037, GO:0002828=GO_REF:0000019, GO:0043236=PMID:19275936, GO:0004871=PMID:12761501, GO:0019899=PMID:20870722, GO:0043123=PMID:12761501} Q16610 Extracellular matrix protein 1 protein 20130413 {GO:0005515=IPI, GO:2000404=IEA, GO:0005134=IEA, GO:0006357=IEA, GO:0010466=IDA, GO:0005578=NAS, GO:0001525=IEA, GO:0030502=IDA, GO:0002020=IPI, GO:0008022=IPI, GO:0031214=IEA, GO:0005615=IEA, GO:0045766=IDA, GO:0031012=IDA, GO:0007165=IMP, GO:0006954=IEA, GO:0001960=IEA, GO:0001938=IDA, GO:0001503=IEA, GO:0002828=IEA, GO:0043236=IPI, GO:0004871=IMP, GO:0019899=IPI, GO:0043123=IMP} angiogenesis, biomineral tissue development, inflammatory response, negative regulation of bone mineralization, negative regulation of cytokine-mediated signaling pathway, negative regulation of peptidase activity, ossification, positive regulation of I-kappaB kinase/NF-kappaB cascade, positive regulation of angiogenesis, positive regulation of endothelial cell proliferation, regulation of T cell migration, regulation of transcription from RNA polymerase II promoter, regulation of type 2 immune response, signal transduction extracellular matrix, extracellular space, proteinaceous extracellular matrix enzyme binding, interleukin-2 receptor binding, laminin binding, protease binding, protein C-terminus binding, protein binding, signal transducer activity Human ECSCR UniProtKB UniProtKB {GO:0005886=GO_REF:0000039, GO:0006935=GO_REF:0000037, GO:0016021=GO_REF:0000037, GO:0001525=GO_REF:0000037, GO:0030154=GO_REF:0000037} Q19T08 Endothelial cell-specific chemotaxis regulator protein 20130413 {GO:0005886=IEA, GO:0006935=IEA, GO:0016021=IEA, GO:0001525=IEA, GO:0030154=IEA} angiogenesis, cell differentiation, chemotaxis integral to membrane, plasma membrane Human UniProtKB-SubCell:SL-0039 ECSIT HPA UniProtKB {GO:0005515=PMID:21163940, GO:0051341=PMID:17344420, GO:0005667=GO_REF:0000019, GO:0001707=GO_REF:0000019, GO:0003700=GO_REF:0000019, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0030509=GO_REF:0000019, GO:0005739=PMID:17344420, GO:0005737=GO_REF:0000052, GO:0045087=GO_REF:0000037, GO:0016651=PMID:17344420, GO:0004871=GO_REF:0000019} Q9BQ95 Evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial protein 20111111 {GO:0005515=IPI, GO:0051341=IDA, GO:0005667=IEA, GO:0001707=IEA, GO:0003700=IEA, GO:0005730=IDA, GO:0005634=IDA, GO:0030509=IEA, GO:0005739=IDA, GO:0005737=IDA, GO:0045087=IEA, GO:0016651=IDA, GO:0004871=IEA} BMP signaling pathway, innate immune response, mesoderm formation, regulation of oxidoreductase activity cytoplasm, mitochondrion, nucleolus, nucleus, transcription factor complex oxidoreductase activity, acting on NAD(P)H, protein binding, sequence-specific DNA binding transcription factor activity, signal transducer activity Human ECT2 IntAct UniProtKB {GO:0005515=PMID:17474147, GO:0045859=PMID:15254234, GO:0072686=PMID:20047078, GO:0070301=PMID:21373644, GO:0007264=Reactome:REACT_11044, GO:0035023=GO_REF:0000002, GO:0005634=PMID:20047078, GO:0015031=GO_REF:0000037, GO:0032154=PMID:20047078, GO:0042803=PMID:15545273, GO:0005829=Reactome:REACT_19216, GO:0035556=GO_REF:0000002, GO:0005085=GO_REF:0000002, GO:0032147=PMID:15254234, GO:0000910=GO_REF:0000002, GO:0005737=PMID:20047078, GO:0005543=GO_REF:0000002, GO:0070830=PMID:15254234, GO:0005911=PMID:15254234, GO:0043089=PMID:19617897, GO:0071277=PMID:15254234, GO:0051260=PMID:15545273, GO:0004871=PMID:12761501, GO:0005089=PMID:12761501, GO:0043123=PMID:12761501, GO:0051056=Reactome:REACT_11051, GO:0048011=Reactome:REACT_13776, GO:0043065=PMID:21373644, GO:0051988=PMID:15642749, GO:0006915=Reactome:REACT_13638, GO:0030496=PMID:15545273, GO:0032862=PMID:19617897, GO:0032863=PMID:19617897, GO:0097190=Reactome:REACT_13720, GO:0071479=PMID:21373644, GO:0000902=GO_REF:0000019, GO:0032321=PMID:21373644, GO:0045666=GO_REF:0000024, GO:0042307=GO_REF:0000024, GO:0017048=GO_REF:0000019, GO:0097149=PMID:16236794, GO:0005923=PMID:15254234, GO:0005096=PMID:15642749} Q9H8V3 Protein ECT2 protein 20130415 {GO:0005515=IPI, GO:0045859=IDA, GO:0072686=IDA, GO:0070301=IDA, GO:0007264=TAS, GO:0035023=IEA, GO:0005634=IDA, GO:0015031=IEA, GO:0032154=IDA, GO:0042803=IDA, GO:0005829=TAS, GO:0035556=IEA, GO:0005085=IEA, GO:0032147=IDA, GO:0000910=IEA, GO:0005737=IDA, GO:0005543=IEA, GO:0070830=IMP, GO:0005911=IDA, GO:0043089=IDA, GO:0071277=IDA, GO:0051260=IDA, GO:0004871=IMP, GO:0005089=IDA, GO:0043123=IMP, GO:0051056=TAS, GO:0048011=TAS, GO:0043065=IDA, GO:0051988=IMP, GO:0006915=TAS, GO:0030496=IDA, GO:0032862=IDA, GO:0032863=IMP, GO:0097190=TAS, GO:0071479=IDA, GO:0000902=IEA, GO:0032321=IMP, GO:0045666=ISS, GO:0042307=ISS, GO:0017048=IEA, GO:0097149=IDA, GO:0005923=IDA, GO:0005096=IMP} activation of Rac GTPase activity, activation of Rho GTPase activity, activation of protein kinase activity, apoptotic process, apoptotic signaling pathway, cell morphogenesis, cellular response to calcium ion, cellular response to hydrogen peroxide, cellular response to ionizing radiation, cytokinesis, intracellular signal transduction, neurotrophin TRK receptor signaling pathway, positive regulation of Cdc42 GTPase activity, positive regulation of I-kappaB kinase/NF-kappaB cascade, positive regulation of Rho GTPase activity, positive regulation of apoptotic process, positive regulation of neuron differentiation, positive regulation of protein import into nucleus, protein homooligomerization, protein transport, regulation of Rho protein signal transduction, regulation of attachment of spindle microtubules to kinetochore, regulation of protein kinase activity, regulation of small GTPase mediated signal transduction, small GTPase mediated signal transduction, tight junction assembly cell-cell junction, centralspindlin complex, cleavage furrow, cytoplasm, cytosol, midbody, mitotic spindle, nucleus, tight junction GTPase activator activity, Rho GTPase binding, Rho guanyl-nucleotide exchange factor activity, guanyl-nucleotide exchange factor activity, phospholipid binding, protein binding, protein homodimerization activity, signal transducer activity Human UniProtKB:P16333 EDA HGNC UniProtKB {GO:0005515=PMID:11039935, GO:0042346=GO_REF:0000019, GO:0010467=GO_REF:0000019, GO:0005581=GO_REF:0000037, GO:0005886=PMID:9736768, GO:0090263=GO_REF:0000019, GO:0030154=GO_REF:0000037, GO:0006955=GO_REF:0000002, GO:0051092=PMID:11039935, GO:0042475=GO_REF:0000019, GO:0060662=GO_REF:0000019, GO:0043123=GO_REF:0000019, GO:0005856=PMID:10484778, GO:0005164=GO_REF:0000002, GO:0005102=PMID:11039935, GO:0045177=GO_REF:0000019, GO:0060789=GO_REF:0000019, GO:0007398=PMID:8696334, GO:0007165=PMID:8696334, GO:0007160=GO_REF:0000019, GO:0016020=PMID:8696334, GO:0061153=GO_REF:0000019, GO:0005887=GO_REF:0000019, GO:0043473=GO_REF:0000019, GO:0005789=GO_REF:0000019, GO:0043588=GO_REF:0000019, GO:0016021=PMID:8696334} Q92838 Ectodysplasin-A protein 20040813 {GO:0005515=IPI, GO:0042346=IEA, GO:0010467=IEA, GO:0005581=IEA, GO:0005886=TAS, GO:0090263=IEA, GO:0030154=IEA, GO:0006955=IEA, GO:0051092=IDA, GO:0042475=IEA, GO:0060662=IEA, GO:0043123=IEA, GO:0005856=TAS, GO:0005164=IEA, GO:0005102=IDA, GO:0045177=IEA, GO:0060789=IEA, GO:0007398=TAS, GO:0007165=TAS, GO:0007160=IEA, GO:0016020=TAS, GO:0061153=IEA, GO:0005887=IEA, GO:0043473=IEA, GO:0005789=IEA, GO:0043588=IEA, GO:0016021=TAS} cell differentiation, cell-matrix adhesion, ectoderm development, gene expression, hair follicle placode formation, immune response, odontogenesis of dentin-containing tooth, pigmentation, positive regulation of I-kappaB kinase/NF-kappaB cascade, positive regulation of NF-kappaB import into nucleus, positive regulation of NF-kappaB transcription factor activity, positive regulation of canonical Wnt receptor signaling pathway, salivary gland cavitation, signal transduction, skin development, trachea gland development apical part of cell, collagen, cytoskeleton, endoplasmic reticulum membrane, integral to membrane, integral to plasma membrane, membrane, plasma membrane protein binding, receptor binding, tumor necrosis factor receptor binding Human EDA2R GOC UniProtKB {GO:0005515=PMID:11039935, GO:0051092=PMID:11039935, GO:0005031=PMID:11039935, GO:0008544=PMID:11039935, GO:0005887=GO_REF:0000002, GO:0046330=PMID:12270937, GO:0004872=PMID:11039935, GO:0009790=PMID:12270937, GO:0016021=PMID:12270937, GO:0033209=PMID:11039935, GO:0030154=GO_REF:0000037} Q9HAV5 Tumor necrosis factor receptor superfamily member 27 protein 20130413 {GO:0005515=IPI, GO:0051092=IDA, GO:0005031=NAS, GO:0008544=NAS, GO:0005887=IEA, GO:0046330=IDA, GO:0004872=IDA, GO:0009790=NAS, GO:0016021=IC, GO:0033209=NAS, GO:0030154=IEA} cell differentiation, embryo development, epidermis development, positive regulation of JNK cascade, positive regulation of NF-kappaB transcription factor activity, tumor necrosis factor-mediated signaling pathway integral to membrane, integral to plasma membrane protein binding, receptor activity, tumor necrosis factor-activated receptor activity Human EDAR HGNC UniProtKB {GO:0005515=PMID:11039935, GO:0042346=GO_REF:0000019, GO:0005886=GO_REF:0000019, GO:0006915=GO_REF:0000037, GO:0045177=GO_REF:0000019, GO:0030154=GO_REF:0000037, GO:0007165=GO_REF:0000002, GO:0008544=PMID:12270937, GO:0043473=GO_REF:0000019, GO:0042475=GO_REF:0000019, GO:0004872=PMID:11039935, GO:0060662=GO_REF:0000019, GO:0016021=PMID:10431241, GO:0001942=GO_REF:0000019, GO:0004888=PMID:10431241} Q9UNE0 Tumor necrosis factor receptor superfamily member EDAR protein 20040813 {GO:0005515=IPI, GO:0042346=IEA, GO:0005886=IEA, GO:0006915=IEA, GO:0045177=IEA, GO:0030154=IEA, GO:0007165=IEA, GO:0008544=TAS, GO:0043473=IEA, GO:0042475=IEA, GO:0004872=IDA, GO:0060662=IEA, GO:0016021=NAS, GO:0001942=IEA, GO:0004888=NAS} apoptotic process, cell differentiation, epidermis development, hair follicle development, odontogenesis of dentin-containing tooth, pigmentation, positive regulation of NF-kappaB import into nucleus, salivary gland cavitation, signal transduction apical part of cell, integral to membrane, plasma membrane protein binding, receptor activity, transmembrane signaling receptor activity Human UniProtKB:Q92838 EDARADD UniProtKB UniProtKB {GO:0007165=GO_REF:0000002, GO:0005737=GO_REF:0000039, GO:0061153=GO_REF:0000019, GO:0042475=GO_REF:0000019, GO:0001942=GO_REF:0000019, GO:0030154=GO_REF:0000037} Q8WWZ3 Ectodysplasin-A receptor-associated adapter protein protein 20130413 {GO:0007165=IEA, GO:0005737=IEA, GO:0061153=IEA, GO:0042475=IEA, GO:0001942=IEA, GO:0030154=IEA} cell differentiation, hair follicle development, odontogenesis of dentin-containing tooth, signal transduction, trachea gland development cytoplasm Human UniProtKB-SubCell:SL-0086 EDC3 IntAct UniProtKB {GO:0005515=PMID:16364915, GO:0010467=Reactome:REACT_71, GO:0016070=Reactome:REACT_21257, GO:0016071=Reactome:REACT_20605, GO:0000932=GO_REF:0000039, GO:0003723=GO_REF:0000037, GO:0043928=Reactome:REACT_20518, GO:0042802=PMID:18678652, GO:0005829=Reactome:REACT_20560, GO:0000288=Reactome:REACT_20639} Q96F86 Enhancer of mRNA-decapping protein 3 protein 20130415 {GO:0005515=IPI, GO:0010467=TAS, GO:0016070=TAS, GO:0016071=TAS, GO:0000932=IEA, GO:0003723=IEA, GO:0043928=TAS, GO:0042802=IPI, GO:0005829=TAS, GO:0000288=TAS} RNA metabolic process, exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay, gene expression, mRNA metabolic process, nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay cytoplasmic mRNA processing body, cytosol RNA binding, identical protein binding, protein binding Human UniProtKB:Q96F86 EDC4 HPA UniProtKB {GO:0005515=PMID:21903422, GO:0010467=Reactome:REACT_71, GO:0016070=Reactome:REACT_21257, GO:0016071=Reactome:REACT_20605, GO:0005730=GO_REF:0000052, GO:0043928=Reactome:REACT_20518, GO:0005634=GO_REF:0000052, GO:0005829=Reactome:REACT_20560, GO:0043231=GO_REF:0000052, GO:0008150=GO_REF:0000015, GO:0005737=PMID:9067524, GO:0000932=PMID:20826699, GO:0000288=Reactome:REACT_20639} Q6P2E9 Enhancer of mRNA-decapping protein 4 protein 20110516 {GO:0005515=IPI, GO:0010467=TAS, GO:0016070=TAS, GO:0016071=TAS, GO:0005730=IDA, GO:0043928=TAS, GO:0005634=IDA, GO:0005829=TAS, GO:0043231=IDA, GO:0008150=ND, GO:0005737=TAS, GO:0000932=IDA, GO:0000288=TAS} RNA metabolic process, biological_process, exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay, gene expression, mRNA metabolic process, nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay cytoplasm, cytoplasmic mRNA processing body, cytosol, intracellular membrane-bounded organelle, nucleolus, nucleus protein binding Human EDEM1 Reactome UniProtKB {GO:0005515=PMID:19524542, GO:0004571=PMID:12610306, GO:0005509=GO_REF:0000002, GO:0030176=GO_REF:0000024, GO:0030433=GO_REF:0000024, GO:0030968=Reactome:REACT_18356, GO:0051787=PMID:19524542, GO:0016020=GO_REF:0000002, GO:0006457=Reactome:REACT_23878, GO:0005789=Reactome:REACT_116092, GO:0006987=Reactome:REACT_18368, GO:0044267=Reactome:REACT_17015, GO:0018279=Reactome:REACT_22426, GO:0043687=Reactome:REACT_22161} Q92611 ER degradation-enhancing alpha-mannosidase-like protein 1 protein 20130301 {GO:0005515=IPI, GO:0004571=IDA, GO:0005509=IEA, GO:0030176=ISS, GO:0030433=ISS, GO:0030968=TAS, GO:0051787=IDA, GO:0016020=IEA, GO:0006457=TAS, GO:0005789=TAS, GO:0006987=TAS, GO:0044267=TAS, GO:0018279=TAS, GO:0043687=TAS} ER-associated protein catabolic process, activation of signaling protein activity involved in unfolded protein response, cellular protein metabolic process, endoplasmic reticulum unfolded protein response, post-translational protein modification, protein N-linked glycosylation via asparagine, protein folding endoplasmic reticulum membrane, integral to endoplasmic reticulum membrane, membrane calcium ion binding, mannosyl-oligosaccharide 1,2-alpha-mannosidase activity, misfolded protein binding, protein binding Human EDEM2 Reactome UniProtKB {GO:0006986=GO_REF:0000037, GO:0016020=GO_REF:0000002, GO:0006457=Reactome:REACT_23878, GO:0005509=GO_REF:0000002, GO:0004571=PMID:15537790, GO:0005789=Reactome:REACT_25207, GO:0005788=GO_REF:0000039, GO:0005576=GO_REF:0000039, GO:0044267=Reactome:REACT_17015, GO:0043687=Reactome:REACT_22161, GO:0018279=Reactome:REACT_22426} Q9BV94 ER degradation-enhancing alpha-mannosidase-like protein 2 protein 20130301 {GO:0006986=IEA, GO:0016020=IEA, GO:0006457=TAS, GO:0005509=IEA, GO:0004571=IDA, GO:0005789=TAS, GO:0005788=IEA, GO:0005576=IEA, GO:0044267=TAS, GO:0043687=TAS, GO:0018279=TAS} cellular protein metabolic process, post-translational protein modification, protein N-linked glycosylation via asparagine, protein folding, response to unfolded protein endoplasmic reticulum lumen, endoplasmic reticulum membrane, extracellular region, membrane calcium ion binding, mannosyl-oligosaccharide 1,2-alpha-mannosidase activity Human EDEM3 Reactome UniProtKB {GO:0006986=GO_REF:0000037, GO:0004571=GO_REF:0000003, GO:0005509=GO_REF:0000002, GO:0016020=GO_REF:0000002, GO:0006457=Reactome:REACT_23878, GO:0005789=Reactome:REACT_25207, GO:0005788=GO_REF:0000039, GO:0006516=GO_REF:0000019, GO:0043161=GO_REF:0000019, GO:0004569=GO_REF:0000019, GO:0044267=Reactome:REACT_17015, GO:0018279=Reactome:REACT_22426, GO:0043687=Reactome:REACT_22161} Q9BZQ6 ER degradation-enhancing alpha-mannosidase-like protein 3 protein 20130301 {GO:0006986=IEA, GO:0004571=IEA, GO:0005509=IEA, GO:0016020=IEA, GO:0006457=TAS, GO:0005789=TAS, GO:0005788=IEA, GO:0006516=IEA, GO:0043161=IEA, GO:0004569=IEA, GO:0044267=TAS, GO:0018279=TAS, GO:0043687=TAS} cellular protein metabolic process, glycoprotein catabolic process, post-translational protein modification, proteasomal ubiquitin-dependent protein catabolic process, protein N-linked glycosylation via asparagine, protein folding, response to unfolded protein endoplasmic reticulum lumen, endoplasmic reticulum membrane, membrane calcium ion binding, glycoprotein endo-alpha-1,2-mannosidase activity, mannosyl-oligosaccharide 1,2-alpha-mannosidase activity Human EDF1 HPA UniProtKB {GO:0005515=PMID:12040021, GO:0005516=GO_REF:0000037, GO:0006355=PMID:12040021, GO:0005669=PMID:12040021, GO:0003700=PMID:12040021, GO:0003713=PMID:12040021, GO:0008168=PMID:12040021, GO:0005730=GO_REF:0000052, GO:0007275=GO_REF:0000037, GO:0005634=GO_REF:0000052, GO:0006351=GO_REF:0000037, GO:0019216=PMID:12040021, GO:0005622=PMID:9813014, GO:0043565=GO_REF:0000002, GO:0005737=GO_REF:0000052, GO:0043388=PMID:10567391, GO:0045446=PMID:12040021, GO:0045893=PMID:8164657, GO:0004402=PMID:12040021} O60869 Endothelial differentiation-related factor 1 protein 20101115 {GO:0005515=IPI, GO:0005516=IEA, GO:0006355=TAS, GO:0005669=IDA, GO:0003700=IMP, GO:0003713=IMP, GO:0008168=IDA, GO:0005730=IDA, GO:0007275=IEA, GO:0005634=IDA, GO:0006351=IEA, GO:0019216=TAS, GO:0005622=TAS, GO:0043565=IEA, GO:0005737=IDA, GO:0043388=IDA, GO:0045446=TAS, GO:0045893=TAS, GO:0004402=IDA} endothelial cell differentiation, multicellular organismal development, positive regulation of DNA binding, positive regulation of transcription, DNA-dependent, regulation of lipid metabolic process, regulation of transcription, DNA-dependent, transcription, DNA-dependent cytoplasm, intracellular, nucleolus, nucleus, transcription factor TFIID complex calmodulin binding, histone acetyltransferase activity, methyltransferase activity, protein binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, transcription coactivator activity Human EDIL3 PINC UniProtKB {GO:0005178=PMID:9420328, GO:0010811=GO_REF:0000019, GO:0005509=GO_REF:0000002, GO:0007275=GO_REF:0000037, GO:0007155=GO_REF:0000037} O43854 EGF-like repeat and discoidin I-like domain-containing protein 3 protein 20030904 {GO:0005178=TAS, GO:0010811=IEA, GO:0005509=IEA, GO:0007275=IEA, GO:0007155=IEA} cell adhesion, multicellular organismal development, positive regulation of cell-substrate adhesion calcium ion binding, integrin binding Human EDN1 BHF-UCL UniProtKB {GO:0019722=PMID:10770212, GO:0051216=GO_REF:0000019, GO:0005615=PMID:10770212, GO:0006885=GO_REF:0000019, GO:0007243=GO_REF:0000019, GO:0019229=GO_REF:0000002, GO:0007507=GO_REF:0000019, GO:0046888=GO_REF:0000019, GO:0070101=PMID:17178876, GO:0015758=GO_REF:0000019, GO:0014032=GO_REF:0000019, GO:0001516=PMID:9492062, GO:0051482=GO_REF:0000019, GO:0046887=PMID:10770212, GO:0071356=GO_REF:0000019, GO:0032496=GO_REF:0000019, GO:0003100=PMID:2649896, GO:0031583=GO_REF:0000019, GO:0030335=PMID:9696419, GO:0043179=GO_REF:0000019, GO:0030593=PMID:9696419, GO:0060137=GO_REF:0000019, GO:0045840=PMID:10770212, GO:0000122=PMID:19767294, GO:0060585=PMID:9492062, GO:0005125=PMID:19767294, GO:0014065=PMID:17078114, GO:0001701=GO_REF:0000019, GO:0032269=PMID:19767294, GO:0010595=PMID:8999856, GO:0045793=PMID:12847114, GO:0045321=PMID:16820593, GO:0007186=PMID:17078114, GO:0005179=PMID:2649896, GO:0035815=GO_REF:0000019, GO:0071347=GO_REF:0000019, GO:0090023=GO_REF:0000019, GO:0016049=GO_REF:0000019, GO:0010460=PMID:2649896, GO:0030072=PMID:10770212, GO:0035810=GO_REF:0000019, GO:0051930=GO_REF:0000019, GO:0008284=PMID:1917960, GO:0051899=GO_REF:0000019, GO:0042482=GO_REF:0000019, GO:0030818=GO_REF:0000019, GO:0007267=PMID:12379507, GO:0031707=PMID:10770212, GO:0010259=GO_REF:0000019, GO:0010870=PMID:17178876, GO:0009953=GO_REF:0000019, GO:0031708=PMID:10770212, GO:0007204=PMID:1917960, GO:0007205=GO_REF:0000019, GO:0045429=PMID:8999856, GO:0042313=PMID:16820593, GO:0042045=GO_REF:0000019, GO:0005737=PMID:12379507, GO:0045987=GO_REF:0000019, GO:0043406=PMID:10770212, GO:0030185=PMID:16820593, GO:0042310=PMID:2649896, GO:0042474=GO_REF:0000019, GO:0043507=PMID:12847114, GO:0043200=GO_REF:0000019, GO:0010613=PMID:12847114, GO:0042554=GO_REF:0000019, GO:0014824=PMID:8982507, GO:0007589=GO_REF:0000019, GO:0001666=GO_REF:0000019, GO:0014826=PMID:9422810, GO:0001569=GO_REF:0000019, GO:0001821=GO_REF:0000019, GO:0007585=GO_REF:0000019, GO:0048016=PMID:1917960, GO:0005576=Reactome:REACT_22436, GO:0033574=GO_REF:0000019, GO:0048661=PMID:10393673, GO:0019233=GO_REF:0000019, GO:0034392=GO_REF:0000019, GO:0060298=PMID:12847114, GO:0030195=PMID:16820593, GO:0051771=PMID:16820593, GO:0007166=PMID:1713452, GO:0035094=GO_REF:0000019} P05305 Endothelin-1 protein 20110318 {GO:0019722=IDA, GO:0051216=IEA, GO:0005615=IDA, GO:0006885=IEA, GO:0007243=IEA, GO:0019229=IEA, GO:0007507=IEA, GO:0046888=IEA, GO:0070101=IC, GO:0015758=IEA, GO:0014032=IEA, GO:0001516=IDA, GO:0051482=IEA, GO:0046887=IDA, GO:0071356=IEA, GO:0032496=IEA, GO:0003100=IDA, GO:0031583=IEA, GO:0030335=IDA, GO:0043179=IEA, GO:0030593=IDA, GO:0060137=IEA, GO:0045840=IDA, GO:0000122=IDA, GO:0060585=IMP, GO:0005125=IDA, GO:0014065=IDA, GO:0001701=IEA, GO:0032269=IDA, GO:0010595=TAS, GO:0045793=IDA, GO:0045321=TAS, GO:0007186=IDA, GO:0005179=IDA, GO:0035815=IEA, GO:0071347=IEA, GO:0090023=IEA, GO:0016049=IEA, GO:0010460=IDA, GO:0030072=IDA, GO:0035810=IEA, GO:0051930=IEA, GO:0008284=IDA, GO:0051899=IEA, GO:0042482=IEA, GO:0030818=IEA, GO:0007267=IDA, GO:0031707=IDA, GO:0010259=IEA, GO:0010870=IDA, GO:0009953=IEA, GO:0031708=IDA, GO:0007204=IDA, GO:0007205=IEA, GO:0045429=TAS, GO:0042313=IDA, GO:0042045=IEA, GO:0005737=IDA, GO:0045987=IEA, GO:0043406=IDA, GO:0030185=IDA, GO:0042310=IDA, GO:0042474=IEA, GO:0043507=IDA, GO:0043200=IEA, GO:0010613=IDA, GO:0042554=IEA, GO:0014824=IDA, GO:0007589=IEA, GO:0001666=IEA, GO:0014826=IDA, GO:0001569=IEA, GO:0001821=IEA, GO:0007585=IEA, GO:0048016=IDA, GO:0005576=TAS, GO:0033574=IEA, GO:0048661=IDA, GO:0019233=IEA, GO:0034392=IEA, GO:0060298=IMP, GO:0030195=TAS, GO:0051771=IDA, GO:0007166=IDA, GO:0035094=IEA} G-protein coupled receptor signaling pathway, artery smooth muscle contraction, body fluid secretion, calcium-mediated signaling, cartilage development, cell growth, cell surface receptor signaling pathway, cell-cell signaling, cellular response to interleukin-1, cellular response to tumor necrosis factor, dorsal/ventral pattern formation, elevation of cytosolic calcium ion concentration, elevation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway, epithelial fluid transport, glucose transport, heart development, histamine secretion, in utero embryonic development, inositol phosphate-mediated signaling, intracellular protein kinase cascade, leukocyte activation, maternal process involved in parturition, membrane depolarization, middle ear morphogenesis, multicellular organismal aging, negative regulation of blood coagulation, negative regulation of cAMP biosynthetic process, negative regulation of cellular protein metabolic process, negative regulation of hormone secretion, negative regulation of nitric-oxide synthase biosynthetic process, negative regulation of smooth muscle cell apoptotic process, negative regulation of transcription from RNA polymerase II promoter, neural crest cell development, neutrophil chemotaxis, nitric oxide transport, patterning of blood vessels, peptide hormone secretion, phosphatidylinositol 3-kinase cascade, phospholipase D-activating G-protein coupled receptor signaling pathway, positive regulation of JUN kinase activity, positive regulation of MAP kinase activity, positive regulation of cardiac muscle hypertrophy, positive regulation of cell migration, positive regulation of cell proliferation, positive regulation of cell size, positive regulation of chemokine-mediated signaling pathway, positive regulation of endothelial cell migration, positive regulation of heart rate, positive regulation of hormone secretion, positive regulation of mitosis, positive regulation of neutrophil chemotaxis, positive regulation of nitric oxide biosynthetic process, positive regulation of odontogenesis, positive regulation of prostaglandin-endoperoxide synthase activity, positive regulation of receptor biosynthetic process, positive regulation of renal sodium excretion, positive regulation of sarcomere organization, positive regulation of smooth muscle cell proliferation, positive regulation of smooth muscle contraction, positive regulation of urine volume, prostaglandin biosynthetic process, protein kinase C deactivation, protein kinase C-activating G-protein coupled receptor signaling pathway, regulation of pH, regulation of sensory perception of pain, regulation of systemic arterial blood pressure by endothelin, regulation of vasoconstriction, respiratory gaseous exchange, response to amino acid stimulus, response to hypoxia, response to lipopolysaccharide, response to nicotine, response to testosterone stimulus, rhythmic excitation, sensory perception of pain, superoxide anion generation, vasoconstriction, vein smooth muscle contraction cytoplasm, extracellular region, extracellular space cytokine activity, endothelin A receptor binding, endothelin B receptor binding, hormone activity Human EDN2 BHF-UCL UniProtKB {GO:0014824=PMID:8982507, GO:0008284=PMID:1917960, GO:0014826=PMID:8982507, GO:0019722=PMID:1917960, GO:0030593=PMID:9696419, GO:0019221=PMID:12207323, GO:0048016=PMID:1917960, GO:0005576=Reactome:REACT_22436, GO:0060585=PMID:9492062, GO:0005615=PMID:15691296, GO:0007204=PMID:1917960, GO:0002690=PMID:9696419, GO:0019229=GO_REF:0000002, GO:0005179=PMID:2649896, GO:0042116=PMID:12207323, GO:0001516=PMID:9492062, GO:0003058=PMID:1652300, GO:0045987=GO_REF:0000019, GO:0042310=PMID:2649896, GO:0003099=PMID:1652300, GO:0010460=PMID:2649896, GO:0048246=PMID:12207323, GO:0003100=PMID:2649896, GO:0007166=PMID:1713452} P20800 Endothelin-2 protein 20080903 {GO:0014824=IDA, GO:0008284=IDA, GO:0014826=IDA, GO:0019722=IDA, GO:0030593=IDA, GO:0019221=IDA, GO:0048016=IDA, GO:0005576=TAS, GO:0060585=IMP, GO:0005615=IDA, GO:0007204=IDA, GO:0002690=IDA, GO:0019229=IEA, GO:0005179=IDA, GO:0042116=IDA, GO:0001516=IDA, GO:0003058=TAS, GO:0045987=IEA, GO:0042310=IDA, GO:0003099=TAS, GO:0010460=IDA, GO:0048246=IDA, GO:0003100=IDA, GO:0007166=IC} artery smooth muscle contraction, calcium-mediated signaling, cell surface receptor signaling pathway, cytokine-mediated signaling pathway, elevation of cytosolic calcium ion concentration, hormonal regulation of the force of heart contraction, inositol phosphate-mediated signaling, macrophage activation, macrophage chemotaxis, neutrophil chemotaxis, positive regulation of cell proliferation, positive regulation of heart rate, positive regulation of leukocyte chemotaxis, positive regulation of prostaglandin-endoperoxide synthase activity, positive regulation of smooth muscle contraction, positive regulation of the force of heart contraction by chemical signal, prostaglandin biosynthetic process, regulation of systemic arterial blood pressure by endothelin, regulation of vasoconstriction, vasoconstriction, vein smooth muscle contraction extracellular region, extracellular space hormone activity Human EDN3 InterPro UniProtKB {GO:0008284=GO_REF:0000019, GO:0008015=PMID:8298278, GO:0001755=GO_REF:0000019, GO:0007267=PMID:8298278, GO:0005615=PMID:15691296, GO:0019229=GO_REF:0000002, GO:0043406=PMID:10770212, GO:0030182=GO_REF:0000019, GO:0042310=PMID:2649896, GO:0046887=PMID:10770212, GO:0003100=PMID:2649896, GO:0014824=PMID:8982507, GO:0014826=PMID:8982507, GO:0030593=PMID:9696419, GO:0048016=PMID:1917960, GO:0005102=PMID:8298278, GO:0005576=GO_REF:0000002, GO:0007275=PMID:8630502, GO:0030318=GO_REF:0000019, GO:0045840=PMID:10770212, GO:0002690=PMID:9696419, GO:0007165=PMID:8298278, GO:0048070=GO_REF:0000019, GO:0005179=PMID:2649896, GO:0010460=PMID:2649896, GO:0030072=PMID:10770212, GO:0007166=PMID:1713452} Q4FAT2 Endothelin-3 protein 20130413 {GO:0008284=IEA, GO:0008015=TAS, GO:0001755=IEA, GO:0007267=TAS, GO:0005615=IDA, GO:0019229=IEA, GO:0043406=IDA, GO:0030182=IEA, GO:0042310=IDA, GO:0046887=IDA, GO:0003100=IDA, GO:0014824=IDA, GO:0014826=IDA, GO:0030593=IDA, GO:0048016=IDA, GO:0005102=TAS, GO:0005576=IEA, GO:0007275=TAS, GO:0030318=IEA, GO:0045840=IDA, GO:0002690=IDA, GO:0007165=TAS, GO:0048070=IEA, GO:0005179=IDA, GO:0010460=IDA, GO:0030072=IDA, GO:0007166=IDA} artery smooth muscle contraction, blood circulation, cell surface receptor signaling pathway, cell-cell signaling, inositol phosphate-mediated signaling, melanocyte differentiation, multicellular organismal development, neural crest cell migration, neuron differentiation, neutrophil chemotaxis, peptide hormone secretion, positive regulation of MAP kinase activity, positive regulation of cell proliferation, positive regulation of heart rate, positive regulation of hormone secretion, positive regulation of leukocyte chemotaxis, positive regulation of mitosis, regulation of developmental pigmentation, regulation of systemic arterial blood pressure by endothelin, regulation of vasoconstriction, signal transduction, vasoconstriction, vein smooth muscle contraction extracellular region, extracellular space hormone activity, receptor binding Human InterPro:IPR001928|InterPro:IPR019764 EDNRA BHF-UCL UniProtKB {GO:0007507=GO_REF:0000019, GO:0006939=PMID:9284755, GO:0014032=GO_REF:0000019, GO:0015758=GO_REF:0000024, GO:0051482=GO_REF:0000019, GO:0032496=GO_REF:0000019, GO:0070374=GO_REF:0000019, GO:0050678=GO_REF:0000019, GO:0031965=GO_REF:0000019, GO:0007568=GO_REF:0000019, GO:0060137=GO_REF:0000019, GO:0043278=GO_REF:0000019, GO:0043084=GO_REF:0000019, GO:0001701=GO_REF:0000019, GO:0048484=GO_REF:0000002, GO:0007186=PMID:8611157, GO:0005887=PMID:1326535, GO:0090023=GO_REF:0000019, GO:0008284=GO_REF:0000019, GO:0042482=GO_REF:0000019, GO:0090184=GO_REF:0000019, GO:0005886=Reactome:REACT_22436, GO:0008283=PMID:9284755, GO:0030818=GO_REF:0000019, GO:0007266=GO_REF:0000019, GO:0007202=PMID:8702836, GO:0048144=GO_REF:0000019, GO:0007204=PMID:1849646, GO:0007205=GO_REF:0000019, GO:0007190=PMID:8702836, GO:0042310=PMID:8982507, GO:0051281=GO_REF:0000019, GO:0014824=PMID:8982507, GO:0001666=GO_REF:0000019, GO:0043066=GO_REF:0000019, GO:0001569=GO_REF:0000019, GO:0001821=GO_REF:0000019, GO:0007585=GO_REF:0000024, GO:0030315=GO_REF:0000019, GO:0019233=GO_REF:0000019, GO:0007165=PMID:1326535, GO:0048659=GO_REF:0000019, GO:0016020=GO_REF:0000029, GO:0003094=GO_REF:0000019, GO:0004435=PMID:8702836, GO:0004962=PMID:8611157, GO:0050729=GO_REF:0000019, GO:0008217=GO_REF:0000002, GO:0001934=GO_REF:0000019, GO:0060322=GO_REF:0000019, GO:0071260=GO_REF:0000019} P25101 Endothelin-1 receptor protein 20080903 {GO:0007507=IEA, GO:0006939=NAS, GO:0014032=IEA, GO:0015758=ISS, GO:0051482=IEA, GO:0032496=IEA, GO:0070374=IEA, GO:0050678=IEA, GO:0031965=IEA, GO:0007568=IEA, GO:0060137=IEA, GO:0043278=IEA, GO:0043084=IEA, GO:0001701=IEA, GO:0048484=IEA, GO:0007186=NAS, GO:0005887=TAS, GO:0090023=IEA, GO:0008284=IEA, GO:0042482=IEA, GO:0090184=IEA, GO:0005886=TAS, GO:0008283=NAS, GO:0030818=IEA, GO:0007266=IEA, GO:0007202=TAS, GO:0048144=IEA, GO:0007204=TAS, GO:0007205=IEA, GO:0007190=TAS, GO:0042310=IMP, GO:0051281=IEA, GO:0014824=IMP, GO:0001666=IEA, GO:0043066=IEA, GO:0001569=IEA, GO:0001821=IEA, GO:0007585=ISS, GO:0030315=IEA, GO:0019233=IEA, GO:0007165=TAS, GO:0048659=IEA, GO:0016020=NAS, GO:0003094=IEA, GO:0004435=TAS, GO:0004962=NAS, GO:0050729=IEA, GO:0008217=IEA, GO:0001934=IEA, GO:0060322=IEA, GO:0071260=IEA} G-protein coupled receptor signaling pathway, Rho protein signal transduction, activation of adenylate cyclase activity, activation of phospholipase C activity, aging, artery smooth muscle contraction, cell proliferation, cellular response to mechanical stimulus, elevation of cytosolic calcium ion concentration, elevation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway, enteric nervous system development, fibroblast proliferation, glomerular filtration, glucose transport, head development, heart development, histamine secretion, in utero embryonic development, maternal process involved in parturition, negative regulation of apoptotic process, negative regulation of cAMP biosynthetic process, neural crest cell development, patterning of blood vessels, penile erection, positive regulation of ERK1 and ERK2 cascade, positive regulation of cell proliferation, positive regulation of inflammatory response, positive regulation of kidney development, positive regulation of neutrophil chemotaxis, positive regulation of odontogenesis, positive regulation of protein phosphorylation, positive regulation of release of sequestered calcium ion into cytosol, protein kinase C-activating G-protein coupled receptor signaling pathway, regulation of blood pressure, regulation of epithelial cell proliferation, respiratory gaseous exchange, response to hypoxia, response to lipopolysaccharide, response to morphine, sensory perception of pain, signal transduction, smooth muscle cell proliferation, smooth muscle contraction, vasoconstriction T-tubule, integral to plasma membrane, membrane, nuclear membrane, plasma membrane endothelin receptor activity, phosphatidylinositol phospholipase C activity Human EDNRB GOC UniProtKB {GO:0014070=GO_REF:0000019, GO:0008284=GO_REF:0000019, GO:0005886=Reactome:REACT_22436, GO:0060406=GO_REF:0000019, GO:0001755=GO_REF:0000019, GO:0007200=GO_REF:0000019, GO:0019934=GO_REF:0000019, GO:0007194=PMID:9556633, GO:0007204=GO_REF:0000019, GO:0031702=GO_REF:0000019, GO:0006885=GO_REF:0000019, GO:0042045=GO_REF:0000019, GO:0042311=GO_REF:0000019, GO:0042310=PMID:8982507, GO:0050678=GO_REF:0000019, GO:0014826=PMID:8982507, GO:0031965=GO_REF:0000019, GO:0043066=GO_REF:0000019, GO:0086100=PMID:19767294, GO:0007568=GO_REF:0000019, GO:0014043=GO_REF:0000024, GO:0030318=GO_REF:0000019, GO:0000122=PMID:19767294, GO:0032269=PMID:19767294, GO:0019233=GO_REF:0000019, GO:0048484=GO_REF:0000024, GO:0007399=PMID:8001158, GO:0071222=GO_REF:0000019, GO:0005887=PMID:8810293, GO:0004962=PMID:1713452, GO:0007422=GO_REF:0000019, GO:0035815=GO_REF:0000019, GO:0008217=GO_REF:0000019, GO:0001934=GO_REF:0000019, GO:0007497=GO_REF:0000019, GO:0045121=GO_REF:0000019, GO:0048265=GO_REF:0000019, GO:0048246=PMID:12207323, GO:0017046=PMID:1713452, GO:0035810=GO_REF:0000019, GO:0007166=PMID:8810293, GO:0035645=GO_REF:0000024, GO:0051930=GO_REF:0000019} P24530 Endothelin B receptor protein 20130413 {GO:0014070=IEA, GO:0008284=IEA, GO:0005886=TAS, GO:0060406=IEA, GO:0001755=IEA, GO:0007200=IEA, GO:0019934=IEA, GO:0007194=TAS, GO:0007204=IEA, GO:0031702=IEA, GO:0006885=IEA, GO:0042045=IEA, GO:0042311=IEA, GO:0042310=IMP, GO:0050678=IEA, GO:0014826=IMP, GO:0031965=IEA, GO:0043066=IEA, GO:0086100=IMP, GO:0007568=IEA, GO:0014043=ISS, GO:0030318=IEA, GO:0000122=IMP, GO:0032269=IMP, GO:0019233=IEA, GO:0048484=ISS, GO:0007399=TAS, GO:0071222=IEA, GO:0005887=TAS, GO:0004962=IDA, GO:0007422=IEA, GO:0035815=IEA, GO:0008217=IEA, GO:0001934=IEA, GO:0007497=IEA, GO:0045121=IEA, GO:0048265=IEA, GO:0048246=IMP, GO:0017046=IPI, GO:0035810=IEA, GO:0007166=TAS, GO:0035645=ISS, GO:0051930=IEA} aging, cGMP-mediated signaling, cell surface receptor signaling pathway, cellular response to lipopolysaccharide, elevation of cytosolic calcium ion concentration, endothelin receptor signaling pathway, enteric nervous system development, enteric smooth muscle cell differentiation, epithelial fluid transport, macrophage chemotaxis, melanocyte differentiation, negative regulation of adenylate cyclase activity, negative regulation of apoptotic process, negative regulation of cellular protein metabolic process, negative regulation of neuron maturation, negative regulation of transcription from RNA polymerase II promoter, nervous system development, neural crest cell migration, peripheral nervous system development, phospholipase C-activating G-protein coupled receptor signaling pathway, positive regulation of cell proliferation, positive regulation of penile erection, positive regulation of protein phosphorylation, positive regulation of renal sodium excretion, positive regulation of urine volume, posterior midgut development, regulation of blood pressure, regulation of epithelial cell proliferation, regulation of pH, regulation of sensory perception of pain, response to organic cyclic compound, response to pain, sensory perception of pain, vasoconstriction, vasodilation, vein smooth muscle contraction integral to plasma membrane, membrane raft, nuclear membrane, plasma membrane endothelin receptor activity, peptide hormone binding, type 1 angiotensin receptor binding Human EEA1 HPA UniProtKB {GO:0005515=PMID:11870209, GO:0005516=PMID:11741531, GO:0005969=GO_REF:0000019, GO:0005886=GO_REF:0000052, GO:0045022=PMID:7768953, GO:0006906=PMID:9697774, GO:0042803=PMID:11741531, GO:0006897=PMID:21081650, GO:0005829=PMID:7768953, GO:0005545=PMID:11256955, GO:0005737=GO_REF:0000052, GO:0030742=PMID:10491193, GO:0016020=PMID:7768953, GO:0031901=GO_REF:0000039, GO:0016189=PMID:11741531, GO:0008270=PMID:11741531, GO:0055037=GO_REF:0000019, GO:0005769=PMID:19535332, GO:0019897=PMID:7768953} Q15075 Early endosome antigen 1 protein 20111111 {GO:0005515=IPI, GO:0005516=NAS, GO:0005969=IEA, GO:0005886=IDA, GO:0045022=NAS, GO:0006906=IMP, GO:0042803=IDA, GO:0006897=IMP, GO:0005829=IDA, GO:0005545=IDA, GO:0005737=IDA, GO:0030742=IDA, GO:0016020=TAS, GO:0031901=IEA, GO:0016189=TAS, GO:0008270=TAS, GO:0055037=IEA, GO:0005769=IDA, GO:0019897=IDA} early endosome to late endosome transport, endocytosis, synaptic vesicle to endosome fusion, vesicle fusion cytoplasm, cytosol, early endosome, early endosome membrane, extrinsic to plasma membrane, membrane, plasma membrane, recycling endosome, serine-pyruvate aminotransferase complex 1-phosphatidylinositol binding, GTP-dependent protein binding, calmodulin binding, protein binding, protein homodimerization activity, zinc ion binding Human EED IntAct UniProtKB {GO:0005515=PMID:23238014, GO:0035098=PMID:15385962, GO:0016571=GO_REF:0000019, GO:0003682=GO_REF:0000019, GO:0006349=GO_REF:0000019, GO:0005634=PMID:9584199, GO:0045120=GO_REF:0000019, GO:0045892=PMID:9584199, GO:0001739=GO_REF:0000019, GO:0006351=GO_REF:0000037, GO:0042054=PMID:15385962} O75530 Polycomb protein EED protein 20130415 {GO:0005515=IPI, GO:0035098=IDA, GO:0016571=IEA, GO:0003682=IEA, GO:0006349=IEA, GO:0005634=NAS, GO:0045120=IEA, GO:0045892=NAS, GO:0001739=IEA, GO:0006351=IEA, GO:0042054=IDA} histone methylation, negative regulation of transcription, DNA-dependent, regulation of gene expression by genetic imprinting, transcription, DNA-dependent ESC/E(Z) complex, nucleus, pronucleus, sex chromatin chromatin binding, histone methyltransferase activity, protein binding Human UniProtKB:Q16531 EEF1A1 ENSEMBL UniProtKB {GO:0005515=PMID:18000879, GO:0010467=Reactome:REACT_71, GO:0006355=GO_REF:0000037, GO:0005853=PMID:2564392, GO:0019901=PMID:17595531, GO:0003924=GO_REF:0000002, GO:0005634=GO_REF:0000039, GO:0005525=GO_REF:0000002, GO:0003746=PMID:17595531, GO:0006412=Reactome:REACT_1014, GO:0006351=GO_REF:0000037, GO:0006414=Reactome:REACT_1477, GO:0005829=Reactome:REACT_67, GO:0005737=GO_REF:0000019, GO:0044267=Reactome:REACT_17015} Q5JR01 Elongation factor 1-alpha 1 protein 20130413 {GO:0005515=IPI, GO:0010467=TAS, GO:0006355=IEA, GO:0005853=TAS, GO:0019901=IPI, GO:0003924=IEA, GO:0005634=IEA, GO:0005525=IEA, GO:0003746=TAS, GO:0006412=TAS, GO:0006351=IEA, GO:0006414=TAS, GO:0005829=TAS, GO:0005737=IEA, GO:0044267=TAS} cellular protein metabolic process, gene expression, regulation of transcription, DNA-dependent, transcription, DNA-dependent, translation, translational elongation cytoplasm, cytosol, eukaryotic translation elongation factor 1 complex, nucleus GTP binding, GTPase activity, protein binding, protein kinase binding, translation elongation factor activity Human Ensembl:ENSMUSP00000042457 EEF1A2 PINC UniProtKB {GO:0043066=GO_REF:0000019, GO:0005853=GO_REF:0000019, GO:0010035=GO_REF:0000019, GO:0043025=GO_REF:0000019, GO:0003924=GO_REF:0000002, GO:0005634=GO_REF:0000039, GO:0003746=GO_REF:0000019, GO:0005525=GO_REF:0000037, GO:0008135=PMID:8812466} Q05639 Elongation factor 1-alpha 2 protein 20040811 {GO:0043066=IEA, GO:0005853=IEA, GO:0010035=IEA, GO:0043025=IEA, GO:0003924=IEA, GO:0005634=IEA, GO:0003746=IEA, GO:0005525=IEA, GO:0008135=NAS} negative regulation of apoptotic process, response to inorganic substance eukaryotic translation elongation factor 1 complex, neuronal cell body, nucleus GTP binding, GTPase activity, translation elongation factor activity, translation factor activity, nucleic acid binding Human EEF1B2 IntAct UniProtKB {GO:0005515=PMID:16189514, GO:0010467=Reactome:REACT_71, GO:0005853=PMID:1886777, GO:0003746=PMID:1886777, GO:0044267=Reactome:REACT_17015, GO:0006412=Reactome:REACT_1014, GO:0005829=Reactome:REACT_1395, GO:0006414=Reactome:REACT_1477} P24534 Elongation factor 1-beta protein 20130415 {GO:0005515=IPI, GO:0010467=TAS, GO:0005853=NAS, GO:0003746=NAS, GO:0044267=TAS, GO:0006412=TAS, GO:0005829=TAS, GO:0006414=TAS} cellular protein metabolic process, gene expression, translation, translational elongation cytosol, eukaryotic translation elongation factor 1 complex protein binding, translation elongation factor activity Human UniProtKB:P26641 EEF1D GOC UniProtKB {GO:0005515=PMID:20195357, GO:0010467=Reactome:REACT_71, GO:0005853=GO_REF:0000002, GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0003746=GO_REF:0000037, GO:0003677=GO_REF:0000037, GO:0006412=Reactome:REACT_1014, GO:0006351=GO_REF:0000037, GO:0005829=Reactome:REACT_1395, GO:0006414=Reactome:REACT_1477, GO:0007165=PMID:12761501, GO:0004871=PMID:12761501, GO:0043123=PMID:12761501, GO:0044267=Reactome:REACT_17015, GO:0008135=PMID:8334168} P29692 Elongation factor 1-delta protein 20130413 {GO:0005515=IPI, GO:0010467=TAS, GO:0005853=IEA, GO:0006355=IEA, GO:0005634=IEA, GO:0003746=IEA, GO:0003677=IEA, GO:0006412=TAS, GO:0006351=IEA, GO:0005829=TAS, GO:0006414=TAS, GO:0007165=IMP, GO:0004871=IMP, GO:0043123=IMP, GO:0044267=TAS, GO:0008135=TAS} cellular protein metabolic process, gene expression, positive regulation of I-kappaB kinase/NF-kappaB cascade, regulation of transcription, DNA-dependent, signal transduction, transcription, DNA-dependent, translation, translational elongation cytosol, eukaryotic translation elongation factor 1 complex, nucleus DNA binding, protein binding, signal transducer activity, translation elongation factor activity, translation factor activity, nucleic acid binding Human EEF1E1 HPA UniProtKB {GO:0005515=PMID:22190034, GO:0010467=Reactome:REACT_71, GO:0005737=GO_REF:0000052, GO:0043065=GO_REF:0000024, GO:0008285=GO_REF:0000024, GO:0043517=GO_REF:0000024, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0006418=Reactome:REACT_15482, GO:0005829=Reactome:REACT_15516} O43324 Eukaryotic translation elongation factor 1 epsilon-1 protein 20101115 {GO:0005515=IPI, GO:0010467=TAS, GO:0005737=IDA, GO:0043065=ISS, GO:0008285=ISS, GO:0043517=ISS, GO:0005730=IDA, GO:0005634=IDA, GO:0006418=TAS, GO:0005829=TAS} gene expression, negative regulation of cell proliferation, positive regulation of DNA damage response, signal transduction by p53 class mediator, positive regulation of apoptotic process, tRNA aminoacylation for protein translation cytoplasm, cytosol, nucleolus, nucleus protein binding Human EEF1G IntAct UniProtKB {GO:0005515=PMID:16189514, GO:0005622=GO_REF:0000029, GO:0010467=Reactome:REACT_71, GO:0005853=GO_REF:0000002, GO:0009615=PMID:16548883, GO:0003746=GO_REF:0000029, GO:0044267=Reactome:REACT_17015, GO:0006412=Reactome:REACT_1014, GO:0005829=Reactome:REACT_1395, GO:0006414=Reactome:REACT_1477} P26641 Elongation factor 1-gamma protein 20130415 {GO:0005515=IPI, GO:0005622=NAS, GO:0010467=TAS, GO:0005853=IEA, GO:0009615=IEP, GO:0003746=NAS, GO:0044267=TAS, GO:0006412=TAS, GO:0005829=TAS, GO:0006414=TAS} cellular protein metabolic process, gene expression, response to virus, translation, translational elongation cytosol, eukaryotic translation elongation factor 1 complex, intracellular protein binding, translation elongation factor activity Human UniProtKB:P29692 EEF2 Reactome UniProtKB {GO:0010467=Reactome:REACT_71, GO:0030529=PMID:18809582, GO:0003924=GO_REF:0000019, GO:0005525=GO_REF:0000037, GO:0003746=GO_REF:0000037, GO:0044267=Reactome:REACT_17015, GO:0006412=Reactome:REACT_1014, GO:0005844=GO_REF:0000019, GO:0006414=Reactome:REACT_1477, GO:0005829=Reactome:REACT_2173} P13639 Elongation factor 2 protein 20130213 {GO:0010467=TAS, GO:0030529=IDA, GO:0003924=IEA, GO:0005525=IEA, GO:0003746=IEA, GO:0044267=TAS, GO:0006412=TAS, GO:0005844=IEA, GO:0006414=TAS, GO:0005829=TAS} cellular protein metabolic process, gene expression, translation, translational elongation cytosol, polysome, ribonucleoprotein complex GTP binding, GTPase activity, translation elongation factor activity Human EEF2K Reactome UniProtKB {GO:0008286=Reactome:REACT_498, GO:0005516=PMID:9144159, GO:0005509=GO_REF:0000002, GO:0005524=GO_REF:0000037, GO:0006414=PMID:9144159, GO:0005829=Reactome:REACT_6883, GO:0031952=GO_REF:0000019, GO:0005737=PMID:9144159, GO:0046777=PMID:9144159, GO:0004672=PMID:9144159, GO:0004674=GO_REF:0000002, GO:0004686=PMID:9144159, GO:0008135=PMID:9144159} O00418 Eukaryotic elongation factor 2 kinase protein 20130301 {GO:0008286=TAS, GO:0005516=IDA, GO:0005509=IEA, GO:0005524=IEA, GO:0006414=TAS, GO:0005829=TAS, GO:0031952=IEA, GO:0005737=TAS, GO:0046777=IDA, GO:0004672=TAS, GO:0004674=IEA, GO:0004686=IDA, GO:0008135=TAS} insulin receptor signaling pathway, protein autophosphorylation, regulation of protein autophosphorylation, translational elongation cytoplasm, cytosol ATP binding, calcium ion binding, calmodulin binding, elongation factor-2 kinase activity, protein kinase activity, protein serine/threonine kinase activity, translation factor activity, nucleic acid binding Human EEFSEC GOC UniProtKB {GO:0006184=GO_REF:0000029, GO:0005739=GO_REF:0000019, GO:0005737=GO_REF:0000029, GO:0000049=GO_REF:0000019, GO:0001514=GO_REF:0000019, GO:0003924=GO_REF:0000029, GO:0005634=GO_REF:0000029, GO:0003746=GO_REF:0000029, GO:0005525=GO_REF:0000019, GO:0006414=GO_REF:0000029} P57772 Selenocysteine-specific elongation factor protein 20130413 {GO:0006184=NAS, GO:0005739=IEA, GO:0005737=NAS, GO:0000049=IEA, GO:0001514=IEA, GO:0003924=NAS, GO:0005634=NAS, GO:0003746=NAS, GO:0005525=IEA, GO:0006414=NAS} GTP catabolic process, selenocysteine incorporation, translational elongation cytoplasm, mitochondrion, nucleus GTP binding, GTPase activity, tRNA binding, translation elongation factor activity Human EEPD1 InterPro UniProtKB {GO:0006281=GO_REF:0000002, GO:0003677=GO_REF:0000002} Q7L9B9 Endonuclease/exonuclease/phosphatase family domain-containing protein 1 protein 20130413 {GO:0006281=IEA, GO:0003677=IEA} DNA repair DNA binding Human InterPro:IPR003583 EFCAB1 InterPro UniProtKB {GO:0005509=GO_REF:0000002} Q9HAE3 EF-hand calcium-binding domain-containing protein 1 protein 20130413 {GO:0005509=IEA} calcium ion binding Human InterPro:IPR001125|InterPro:IPR002048|InterPro:IPR011992 EFCAB11 InterPro UniProtKB {GO:0005509=GO_REF:0000002} Q9BUY7 EF-hand calcium-binding domain-containing protein 11 protein 20130413 {GO:0005509=IEA} calcium ion binding Human InterPro:IPR002048|InterPro:IPR011992 EFCAB4A UniProtKB UniProtKB {GO:0005737=GO_REF:0000019, GO:0002115=PMID:20418871, GO:0005509=GO_REF:0000002, GO:2001256=GO_REF:0000019, GO:0034613=GO_REF:0000019} Q8N4Y2 EF-hand calcium-binding domain-containing protein 4A protein 20100430 {GO:0005737=IEA, GO:0002115=IMP, GO:0005509=IEA, GO:2001256=IEA, GO:0034613=IEA} cellular protein localization, regulation of store-operated calcium entry, store-operated calcium entry cytoplasm calcium ion binding Human EFCAB4B HPA UniProtKB {GO:0005515=PMID:20418871, GO:0032237=PMID:20418871, GO:0005737=GO_REF:0000052, GO:0002115=PMID:20418871, GO:0005794=GO_REF:0000052, GO:0051928=PMID:20418871, GO:0005509=PMID:20418871, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052} Q9BSW2 EF-hand calcium-binding domain-containing protein 4B protein 20110516 {GO:0005515=IPI, GO:0032237=IMP, GO:0005737=IDA, GO:0002115=IMP, GO:0005794=IDA, GO:0051928=IMP, GO:0005509=IDA, GO:0005730=IDA, GO:0005634=IDA} activation of store-operated calcium channel activity, positive regulation of calcium ion transport, store-operated calcium entry Golgi apparatus, cytoplasm, nucleolus, nucleus calcium ion binding, protein binding Human EFCAB5 InterPro UniProtKB {GO:0005509=GO_REF:0000002} K7EJC3 EF-hand calcium-binding domain-containing protein 5 protein 20130413 {GO:0005509=IEA} calcium ion binding Human InterPro:IPR002048|InterPro:IPR011992 EFCAB6 UniProtKB UniProtKB {GO:0006355=GO_REF:0000037, GO:0005509=GO_REF:0000002, GO:0005634=GO_REF:0000039, GO:0006351=GO_REF:0000037} Q5THR3 EF-hand calcium-binding domain-containing protein 6 protein 20130413 {GO:0006355=IEA, GO:0005509=IEA, GO:0005634=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus calcium ion binding Human UniProtKB-SubCell:SL-0191 EFEMP1 InterPro UniProtKB {GO:0005515=PMID:16713569, GO:0006355=PMID:20005202, GO:0005154=PMID:19804359, GO:0005509=GO_REF:0000002, GO:0005578=GO_REF:0000039, GO:0018108=PMID:19804359, GO:0005576=Reactome:REACT_150335, GO:0005615=PMID:20005202, GO:0005006=PMID:19804359, GO:0007173=PMID:19804359, GO:0030198=Reactome:REACT_118779, GO:0032331=PMID:20005202, GO:0008083=GO_REF:0000037, GO:0007601=PMID:10369267} Q580Q6 EGF-containing fibulin-like extracellular matrix protein 1 protein 20130413 {GO:0005515=IPI, GO:0006355=IDA, GO:0005154=IDA, GO:0005509=IEA, GO:0005578=IEA, GO:0018108=IDA, GO:0005576=TAS, GO:0005615=IDA, GO:0005006=IDA, GO:0007173=IDA, GO:0030198=TAS, GO:0032331=IDA, GO:0008083=IEA, GO:0007601=TAS} epidermal growth factor receptor signaling pathway, extracellular matrix organization, negative regulation of chondrocyte differentiation, peptidyl-tyrosine phosphorylation, regulation of transcription, DNA-dependent, visual perception extracellular region, extracellular space, proteinaceous extracellular matrix calcium ion binding, epidermal growth factor receptor binding, epidermal growth factor-activated receptor activity, growth factor activity, protein binding Human InterPro:IPR001881|InterPro:IPR018097 EFEMP2 IntAct UniProtKB {GO:0005515=PMID:23088713, GO:0016020=GO_REF:0000002, GO:0030198=Reactome:REACT_118779, GO:0007596=GO_REF:0000002, GO:0005509=GO_REF:0000002, GO:0005576=Reactome:REACT_150335, GO:0005604=PMID:10601734, GO:0005201=PMID:10601734, GO:0004888=GO_REF:0000002} O95967 EGF-containing fibulin-like extracellular matrix protein 2 protein 20130415 {GO:0005515=IPI, GO:0016020=IEA, GO:0030198=TAS, GO:0007596=IEA, GO:0005509=IEA, GO:0005576=TAS, GO:0005604=TAS, GO:0005201=TAS, GO:0004888=IEA} blood coagulation, extracellular matrix organization basement membrane, extracellular region, membrane calcium ion binding, extracellular matrix structural constituent, protein binding, transmembrane signaling receptor activity Human UniProtKB:P09022 EFHC1 UniProtKB UniProtKB {GO:0005929=GO_REF:0000019, GO:0005930=GO_REF:0000024, GO:0005509=GO_REF:0000002, GO:0043025=GO_REF:0000024, GO:0008022=GO_REF:0000024} Q5JVL4 EF-hand domain-containing protein 1 protein 20060201 {GO:0005929=IEA, GO:0005930=ISS, GO:0005509=IEA, GO:0043025=ISS, GO:0008022=ISS} axoneme, cilium, neuronal cell body calcium ion binding, protein C-terminus binding Human UniProtKB:Q9D9T8 EFHC2 InterPro UniProtKB {GO:0005509=GO_REF:0000002} Q5JST6 EF-hand domain-containing family member C2 protein 20130413 {GO:0005509=IEA} calcium ion binding Human InterPro:IPR002048|InterPro:IPR011992 EFHD1 ENSEMBL UniProtKB {GO:0005509=GO_REF:0000002, GO:0005743=GO_REF:0000019, GO:0031175=GO_REF:0000019} Q9BUP0 EF-hand domain-containing protein D1 protein 20130413 {GO:0005509=IEA, GO:0005743=IEA, GO:0031175=IEA} neuron projection development mitochondrial inner membrane calcium ion binding Human Ensembl:ENSMUSP00000027472 EFHD2 UniProtKB UniProtKB {GO:0005509=GO_REF:0000019, GO:0045121=GO_REF:0000039} Q96C19 EF-hand domain-containing protein D2 protein 20130413 {GO:0005509=IEA, GO:0045121=IEA} membrane raft calcium ion binding Human UniProtKB-SubCell:SL-0370 EFNA1 BHF-UCL UniProtKB {GO:0005515=PMID:19573808, GO:0033628=PMID:10655584, GO:0003180=GO_REF:0000024, GO:0050730=GO_REF:0000024, GO:0003183=GO_REF:0000024, GO:0007267=PMID:8660976, GO:0050731=PMID:10655584, GO:0010719=GO_REF:0000024, GO:0014028=GO_REF:0000019, GO:0000187=GO_REF:0000019, GO:0030182=GO_REF:0000019, GO:0034446=PMID:10655584, GO:0046658=GO_REF:0000019, GO:0061002=GO_REF:0000024, GO:0003199=GO_REF:0000024, GO:0048013=PMID:10655584, GO:0005102=PMID:8660976, GO:0045765=GO_REF:0000019, GO:0005576=GO_REF:0000039, GO:0000122=GO_REF:0000024, GO:0001525=GO_REF:0000037, GO:0043535=GO_REF:0000019, GO:0046875=PMID:15777695, GO:0016477=PMID:10655584, GO:0005887=PMID:8660976, GO:0050770=GO_REF:0000019} P20827 Ephrin-A1 protein 20110228 {GO:0005515=IPI, GO:0033628=IDA, GO:0003180=ISS, GO:0050730=ISS, GO:0003183=ISS, GO:0007267=TAS, GO:0050731=IDA, GO:0010719=ISS, GO:0014028=IEA, GO:0000187=IEA, GO:0030182=IEA, GO:0034446=IDA, GO:0046658=IEA, GO:0061002=ISS, GO:0003199=ISS, GO:0048013=IDA, GO:0005102=TAS, GO:0045765=IEA, GO:0005576=IEA, GO:0000122=ISS, GO:0001525=IEA, GO:0043535=IEA, GO:0046875=IPI, GO:0016477=IDA, GO:0005887=TAS, GO:0050770=IEA} activation of MAPK activity, angiogenesis, aortic valve morphogenesis, cell migration, cell-cell signaling, endocardial cushion to mesenchymal transition involved in heart valve formation, ephrin receptor signaling pathway, mitral valve morphogenesis, negative regulation of dendritic spine morphogenesis, negative regulation of epithelial to mesenchymal transition, negative regulation of transcription from RNA polymerase II promoter, neuron differentiation, notochord formation, positive regulation of peptidyl-tyrosine phosphorylation, regulation of angiogenesis, regulation of axonogenesis, regulation of blood vessel endothelial cell migration, regulation of cell adhesion mediated by integrin, regulation of peptidyl-tyrosine phosphorylation, substrate adhesion-dependent cell spreading anchored to plasma membrane, extracellular region, integral to plasma membrane ephrin receptor binding, protein binding, receptor binding Human UniProtKB:P52793 EFNA2 PINC UniProtKB {GO:0046849=GO_REF:0000024, GO:0048013=GO_REF:0000024, GO:0005886=GO_REF:0000039, GO:0046875=GO_REF:0000019, GO:0007267=PMID:9826538, GO:0030316=GO_REF:0000024, GO:0031225=GO_REF:0000037} O43921 Ephrin-A2 protein 20030904 {GO:0046849=ISS, GO:0048013=ISS, GO:0005886=IEA, GO:0046875=IEA, GO:0007267=TAS, GO:0030316=ISS, GO:0031225=IEA} bone remodeling, cell-cell signaling, ephrin receptor signaling pathway, osteoclast differentiation anchored to membrane, plasma membrane ephrin receptor binding Human EFNA3 PINC UniProtKB {GO:0005005=PMID:8660976, GO:0048013=GO_REF:0000024, GO:0046875=PMID:15777695, GO:0016020=GO_REF:0000038, GO:0005887=PMID:8660976, GO:0007267=PMID:8660976, GO:0031225=GO_REF:0000037} P52797 Ephrin-A3 protein 20030904 {GO:0005005=TAS, GO:0048013=ISS, GO:0046875=IPI, GO:0016020=IEA, GO:0005887=TAS, GO:0007267=TAS, GO:0031225=IEA} cell-cell signaling, ephrin receptor signaling pathway anchored to membrane, integral to plasma membrane, membrane ephrin receptor binding, transmembrane-ephrin receptor activity Human EFNA4 PINC UniProtKB {GO:0005515=PMID:15777695, GO:0005005=PMID:8660976, GO:0046875=PMID:15777695, GO:0016020=GO_REF:0000038, GO:0005887=PMID:8660976, GO:0007267=PMID:8660976, GO:0005576=GO_REF:0000039, GO:0031225=GO_REF:0000037} P52798 Ephrin-A4 protein 20030904 {GO:0005515=IPI, GO:0005005=TAS, GO:0046875=IPI, GO:0016020=IEA, GO:0005887=TAS, GO:0007267=TAS, GO:0005576=IEA, GO:0031225=IEA} cell-cell signaling anchored to membrane, extracellular region, integral to plasma membrane, membrane ephrin receptor binding, protein binding, transmembrane-ephrin receptor activity Human EFNA5 PINC UniProtKB {GO:0031290=GO_REF:0000019, GO:0022407=PMID:11870224, GO:0048013=PMID:11870224, GO:0005886=GO_REF:0000024, GO:0050731=GO_REF:0000024, GO:0006915=PMID:11870224, GO:0031362=PMID:11870224, GO:0051893=PMID:11870224, GO:0007399=PMID:9245480, GO:0070507=PMID:11870224, GO:0045499=GO_REF:0000019, GO:0032314=GO_REF:0000024, GO:0016020=GO_REF:0000038, GO:0046875=PMID:11870224, GO:0005901=GO_REF:0000039, GO:0032956=PMID:11870224, GO:0032319=PMID:11870224, GO:0061178=GO_REF:0000024} P52803 Ephrin-A5 protein 20031119 {GO:0031290=IEA, GO:0022407=IDA, GO:0048013=IDA, GO:0005886=ISS, GO:0050731=ISS, GO:0006915=IDA, GO:0031362=IDA, GO:0051893=IDA, GO:0007399=TAS, GO:0070507=IDA, GO:0045499=IEA, GO:0032314=ISS, GO:0016020=IEA, GO:0046875=IPI, GO:0005901=IEA, GO:0032956=IDA, GO:0032319=IDA, GO:0061178=ISS} apoptotic process, ephrin receptor signaling pathway, nervous system development, positive regulation of peptidyl-tyrosine phosphorylation, regulation of Rac GTPase activity, regulation of Rho GTPase activity, regulation of actin cytoskeleton organization, regulation of cell-cell adhesion, regulation of focal adhesion assembly, regulation of insulin secretion involved in cellular response to glucose stimulus, regulation of microtubule cytoskeleton organization, retinal ganglion cell axon guidance anchored to external side of plasma membrane, caveola, membrane, plasma membrane chemorepellent activity, ephrin receptor binding Human EFNB1 PINC UniProtKB {GO:0005515=PMID:9883737, GO:0001755=GO_REF:0000019, GO:0007267=PMID:8798744, GO:0045202=GO_REF:0000024, GO:0005634=GO_REF:0000019, GO:0009880=GO_REF:0000019, GO:0005737=GO_REF:0000019, GO:0046875=GO_REF:0000019, GO:0007411=GO_REF:0000019, GO:0005887=PMID:8660976, GO:0042102=GO_REF:0000019, GO:0045121=GO_REF:0000019, GO:0007155=PMID:8798744} P98172 Ephrin-B1 protein 20030904 {GO:0005515=IPI, GO:0001755=IEA, GO:0007267=TAS, GO:0045202=ISS, GO:0005634=IEA, GO:0009880=IEA, GO:0005737=IEA, GO:0046875=IEA, GO:0007411=IEA, GO:0005887=TAS, GO:0042102=IEA, GO:0045121=IEA, GO:0007155=TAS} axon guidance, cell adhesion, cell-cell signaling, embryonic pattern specification, neural crest cell migration, positive regulation of T cell proliferation cytoplasm, integral to plasma membrane, membrane raft, nucleus, synapse ephrin receptor binding, protein binding Human EFNB2 BHF-UCL UniProtKB {GO:0048013=PMID:12734395, GO:0005886=PMID:8660976, GO:0007267=PMID:8559144, GO:0002042=PMID:12734395, GO:0009653=PMID:9630219, GO:0030154=GO_REF:0000037, GO:2000727=PMID:17336907, GO:0007399=GO_REF:0000037, GO:0046875=PMID:16867992, GO:0050920=PMID:12734395, GO:0005887=PMID:8660976, GO:0019048=GO_REF:0000037, GO:0009887=GO_REF:0000019, GO:0007155=PMID:12734395, GO:0001945=GO_REF:0000019} P52799 Ephrin-B2 protein 20120925 {GO:0048013=IDA, GO:0005886=TAS, GO:0007267=TAS, GO:0002042=IDA, GO:0009653=TAS, GO:0030154=IEA, GO:2000727=ISS, GO:0007399=IEA, GO:0046875=IPI, GO:0050920=IDA, GO:0005887=TAS, GO:0019048=IEA, GO:0009887=IEA, GO:0007155=IDA, GO:0001945=IEA} anatomical structure morphogenesis, cell adhesion, cell differentiation, cell migration involved in sprouting angiogenesis, cell-cell signaling, ephrin receptor signaling pathway, lymph vessel development, nervous system development, organ morphogenesis, positive regulation of cardiac muscle cell differentiation, regulation of chemotaxis, virus-host interaction integral to plasma membrane, plasma membrane ephrin receptor binding Human UniProtKB:P52800 EFNB3 MGI UniProtKB {GO:0005005=PMID:9126477, GO:0048013=PMID:8808709, GO:0046875=PMID:8808709, GO:0005887=PMID:9126477, GO:0016198=GO_REF:0000019, GO:0019048=GO_REF:0000037, GO:0007267=PMID:9126477, GO:0007628=GO_REF:0000019, GO:0007399=PMID:9126477} Q15768 Ephrin-B3 protein 20070125 {GO:0005005=TAS, GO:0048013=IDA, GO:0046875=IDA, GO:0005887=TAS, GO:0016198=IEA, GO:0019048=IEA, GO:0007267=TAS, GO:0007628=IEA, GO:0007399=TAS} adult walking behavior, axon choice point recognition, cell-cell signaling, ephrin receptor signaling pathway, nervous system development, virus-host interaction integral to plasma membrane ephrin receptor binding, transmembrane-ephrin receptor activity Human EFR3A UniProtKB UniProtKB {GO:0005622=GO_REF:0000019, GO:0005886=GO_REF:0000039} Q14156 Protein EFR3 homolog A protein 20130413 {GO:0005622=IEA, GO:0005886=IEA} intracellular, plasma membrane Human UniProtKB-SubCell:SL-0039 EFR3B null null {} null null null null {} null null null EFS PINC UniProtKB {GO:0035556=PMID:9349509, GO:0005737=PMID:9349509, GO:0017124=GO_REF:0000019, GO:0019904=PMID:11984006, GO:0007155=GO_REF:0000037} O43281 Embryonal Fyn-associated substrate protein 20030904 {GO:0035556=TAS, GO:0005737=TAS, GO:0017124=IEA, GO:0019904=IPI, GO:0007155=IEA} cell adhesion, intracellular signal transduction cytoplasm SH3 domain binding, protein domain specific binding Human EFTUD1 UniProtKB UniProtKB {GO:0006184=PMID:21536732, GO:0042256=PMID:21536732, GO:0003924=PMID:21536732, GO:0043022=PMID:21536732, GO:0003746=GO_REF:0000037, GO:0005525=GO_REF:0000037} Q7Z2Z2 Elongation factor Tu GTP-binding domain-containing protein 1 protein 20110516 {GO:0006184=IDA, GO:0042256=IMP, GO:0003924=IDA, GO:0043022=IMP, GO:0003746=IEA, GO:0005525=IEA} GTP catabolic process, mature ribosome assembly GTP binding, GTPase activity, ribosome binding, translation elongation factor activity Human EFTUD2 GOC UniProtKB {GO:0005515=PMID:17314511, GO:0006397=PMID:9233818, GO:0008380=Reactome:REACT_1735, GO:0010467=Reactome:REACT_71, GO:0015030=PMID:15257298, GO:0005730=GO_REF:0000052, GO:0003924=GO_REF:0000002, GO:0005634=GO_REF:0000052, GO:0005525=GO_REF:0000037, GO:0071013=PMID:11991638, GO:0006184=PMID:9233818, GO:0005737=GO_REF:0000052, GO:0016607=PMID:15257298, GO:0000398=Reactome:REACT_1753, GO:0005681=PMID:9233818, GO:0005654=Reactome:REACT_2241} Q15029 116 kDa U5 small nuclear ribonucleoprotein component protein 20130413 {GO:0005515=IPI, GO:0006397=TAS, GO:0008380=TAS, GO:0010467=TAS, GO:0015030=IDA, GO:0005730=IDA, GO:0003924=IEA, GO:0005634=IDA, GO:0005525=IEA, GO:0071013=IDA, GO:0006184=TAS, GO:0005737=IDA, GO:0016607=IDA, GO:0000398=TAS, GO:0005681=TAS, GO:0005654=TAS} GTP catabolic process, RNA splicing, gene expression, mRNA processing, mRNA splicing, via spliceosome Cajal body, catalytic step 2 spliceosome, cytoplasm, nuclear speck, nucleolus, nucleoplasm, nucleus, spliceosomal complex GTP binding, GTPase activity, protein binding Human EGF GOC UniProtKB {GO:0005515=PMID:12620237, GO:0005154=PMID:15611079, GO:0008284=PMID:20388803, GO:0005886=GO_REF:0000019, GO:0051048=PMID:10559227, GO:0007262=GO_REF:0000024, GO:0021940=GO_REF:0000019, GO:0035413=PMID:20302655, GO:0005615=GO_REF:0000019, GO:2000008=PMID:19996314, GO:0007171=PMID:9712850, GO:0000186=GO_REF:0000019, GO:0030297=PMID:9712850, GO:0007173=Reactome:REACT_9417, GO:0043406=PMID:15611079, GO:0031093=Reactome:REACT_21351, GO:0070371=PMID:16314496, GO:0048011=Reactome:REACT_11061, GO:0090279=PMID:19996314, GO:0048015=Reactome:REACT_12464, GO:0045741=PMID:15611079, GO:0005509=GO_REF:0000002, GO:0042059=Reactome:REACT_12484, GO:0030168=Reactome:REACT_798, GO:0018108=GO_REF:0000019, GO:0045840=PMID:15611079, GO:0005576=Reactome:REACT_147854, GO:0001525=PMID:15611079, GO:0006260=PMID:9482941, GO:0007165=Reactome:REACT_12478, GO:2000060=GO_REF:0000019, GO:0008543=Reactome:REACT_9470, GO:0007596=Reactome:REACT_604, GO:0045087=Reactome:REACT_6802, GO:0043388=GO_REF:0000024, GO:0002576=Reactome:REACT_318, GO:0090370=GO_REF:0000019, GO:0048754=GO_REF:0000019, GO:0016021=GO_REF:0000037, GO:0008083=PMID:7736574, GO:0060749=GO_REF:0000019, GO:0042327=PMID:15611079} P01133 Pro-epidermal growth factor protein 20130413 {GO:0005515=IPI, GO:0005154=TAS, GO:0008284=IDA, GO:0005886=IEA, GO:0051048=IDA, GO:0007262=ISS, GO:0021940=IEA, GO:0035413=IDA, GO:0005615=IEA, GO:2000008=IDA, GO:0007171=TAS, GO:0000186=IEA, GO:0030297=TAS, GO:0007173=TAS, GO:0043406=IDA, GO:0031093=TAS, GO:0070371=IDA, GO:0048011=TAS, GO:0090279=IDA, GO:0048015=TAS, GO:0045741=IDA, GO:0005509=IEA, GO:0042059=TAS, GO:0030168=TAS, GO:0018108=IEA, GO:0045840=IDA, GO:0005576=TAS, GO:0001525=IDA, GO:0006260=TAS, GO:0007165=TAS, GO:2000060=IEA, GO:0008543=TAS, GO:0007596=TAS, GO:0045087=TAS, GO:0043388=ISS, GO:0002576=TAS, GO:0090370=IEA, GO:0048754=IEA, GO:0016021=IEA, GO:0008083=IDA, GO:0060749=IEA, GO:0042327=IDA} DNA replication, ERK1 and ERK2 cascade, STAT protein import into nucleus, activation of MAPKK activity, activation of transmembrane receptor protein tyrosine kinase activity, angiogenesis, blood coagulation, branching morphogenesis of an epithelial tube, epidermal growth factor receptor signaling pathway, fibroblast growth factor receptor signaling pathway, innate immune response, mammary gland alveolus development, negative regulation of cholesterol efflux, negative regulation of epidermal growth factor receptor signaling pathway, negative regulation of secretion, neurotrophin TRK receptor signaling pathway, peptidyl-tyrosine phosphorylation, phosphatidylinositol-mediated signaling, platelet activation, platelet degranulation, positive regulation of DNA binding, positive regulation of MAP kinase activity, positive regulation of catenin import into nucleus, positive regulation of cell proliferation, positive regulation of cerebellar granule cell precursor proliferation, positive regulation of epidermal growth factor-activated receptor activity, positive regulation of mitosis, positive regulation of phosphorylation, positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process, regulation of calcium ion import, regulation of protein localization to cell surface, signal transduction extracellular region, extracellular space, integral to membrane, plasma membrane, platelet alpha granule lumen calcium ion binding, epidermal growth factor receptor binding, growth factor activity, protein binding, transmembrane receptor protein tyrosine kinase activator activity Human EGFL6 PINC UniProtKB {GO:0007049=PMID:10610727, GO:0005178=PMID:10610727, GO:0016020=GO_REF:0000002, GO:0030198=GO_REF:0000019, GO:0010811=GO_REF:0000019, GO:0005509=GO_REF:0000002, GO:0007275=GO_REF:0000037, GO:0007155=GO_REF:0000037, GO:0005615=PMID:10610727, GO:0030154=GO_REF:0000037, GO:0005604=GO_REF:0000039} Q8IUX8 Epidermal growth factor-like protein 6 protein 20070906 {GO:0007049=TAS, GO:0005178=TAS, GO:0016020=IEA, GO:0030198=IEA, GO:0010811=IEA, GO:0005509=IEA, GO:0007275=IEA, GO:0007155=IEA, GO:0005615=TAS, GO:0030154=IEA, GO:0005604=IEA} cell adhesion, cell cycle, cell differentiation, extracellular matrix organization, multicellular organismal development, positive regulation of cell-substrate adhesion basement membrane, extracellular space, membrane calcium ion binding, integrin binding Human EGFL7 UniProtKB UniProtKB {GO:0030336=GO_REF:0000019, GO:0001568=GO_REF:0000024, GO:0005509=GO_REF:0000002, GO:0005576=GO_REF:0000024, GO:0001525=GO_REF:0000037, GO:0001570=GO_REF:0000024, GO:0005615=GO_REF:0000019} Q9UHF1 Epidermal growth factor-like protein 7 protein 20041109 {GO:0030336=IEA, GO:0001568=ISS, GO:0005509=IEA, GO:0005576=ISS, GO:0001525=IEA, GO:0001570=ISS, GO:0005615=IEA} angiogenesis, blood vessel development, negative regulation of cell migration, vasculogenesis extracellular region, extracellular space calcium ion binding Human UniProtKB:Q9QXT5 EGFL8 UniProtKB UniProtKB {GO:0008474=GO_REF:0000002, GO:0005509=GO_REF:0000002, GO:0005576=GO_REF:0000039, GO:0016021=GO_REF:0000029, GO:0001701=GO_REF:0000024, GO:0006464=GO_REF:0000002} Q99944 Epidermal growth factor-like protein 8 protein 20041109 {GO:0008474=IEA, GO:0005509=IEA, GO:0005576=IEA, GO:0016021=NAS, GO:0001701=ISS, GO:0006464=IEA} cellular protein modification process, in utero embryonic development extracellular region, integral to membrane calcium ion binding, palmitoyl-(protein) hydrolase activity Human EGFLAM UniProtKB UniProtKB {GO:0019800=GO_REF:0000019, GO:0030054=GO_REF:0000037, GO:0030198=GO_REF:0000019, GO:0010811=GO_REF:0000019, GO:0045202=GO_REF:0000039, GO:0005539=GO_REF:0000019, GO:0005614=GO_REF:0000019, GO:0005604=GO_REF:0000019} Q63HQ2 Pikachurin protein 20130413 {GO:0019800=IEA, GO:0030054=IEA, GO:0030198=IEA, GO:0010811=IEA, GO:0045202=IEA, GO:0005539=IEA, GO:0005614=IEA, GO:0005604=IEA} extracellular matrix organization, peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan, positive regulation of cell-substrate adhesion basement membrane, cell junction, interstitial matrix, synapse glycosaminoglycan binding Human UniProtKB-SubCell:SL-0258 EGFR UniProtKB UniProtKB {GO:0005515=PMID:10805725, GO:0050730=PMID:12435727, GO:0060571=GO_REF:0000019, GO:0005615=PMID:9103388, GO:0042802=PMID:22579287, GO:0005006=PMID:17115032, GO:0016337=PMID:12435727, GO:0021795=GO_REF:0000019, GO:0046777=PMID:18070883, GO:0003690=PMID:6325948, GO:0051015=PMID:14702346, GO:0007173=Reactome:REACT_9417, GO:0000165=PMID:15542601, GO:0007411=Reactome:REACT_18266, GO:0001942=GO_REF:0000019, GO:0004709=PMID:15542601, GO:0050679=PMID:10572067, GO:0031965=GO_REF:0000039, GO:0030335=PMID:12435727, GO:0046982=PMID:10572067, GO:0070435=GO_REF:0000024, GO:0030122=PMID:14702346, GO:0019903=PMID:15899872, GO:0045740=PMID:17115032, GO:0051205=PMID:12435727, GO:0042059=Reactome:REACT_12484, GO:0006950=PMID:12828935, GO:0001892=GO_REF:0000019, GO:0048546=GO_REF:0000019, GO:0070141=PMID:18483258, GO:0001503=PMID:12925580, GO:0008543=Reactome:REACT_9470, GO:0045087=Reactome:REACT_6802, GO:0005789=GO_REF:0000039, GO:0045121=PMID:12009895, GO:0019899=PMID:12009895, GO:0010008=GO_REF:0000039, GO:0004888=PMID:7736574, GO:0043006=PMID:12435727, GO:0051897=PMID:17655843, GO:0008284=PMID:7736574, GO:0048471=GO_REF:0000019, GO:0005886=GO_REF:0000052, GO:0008283=PMID:17115032, GO:0050999=PMID:12828935, GO:0005634=PMID:17115032, GO:0030139=GO_REF:0000019, GO:0048146=GO_REF:0000019, GO:0007202=PMID:12435727, GO:0045739=PMID:17115032, GO:0035413=PMID:20302655, GO:0045429=PMID:12828935, GO:0016323=PMID:12646923, GO:0000186=PMID:15542601, GO:0005737=GO_REF:0000052, GO:0043406=PMID:10572067, GO:0030235=PMID:12828935, GO:0007435=GO_REF:0000019, GO:0048011=Reactome:REACT_11061, GO:0043066=PMID:18070883, GO:0042177=PMID:17115032, GO:0048015=Reactome:REACT_12464, GO:0005524=GO_REF:0000038, GO:0000902=GO_REF:0000019, GO:0007165=Reactome:REACT_12478, GO:0031659=PMID:18483258, GO:0000139=GO_REF:0000039, GO:0016020=PMID:12435727, GO:0016021=GO_REF:0000002, GO:0004713=Reactome:REACT_12569, GO:0004714=GO_REF:0000002, GO:0007169=GO_REF:0000002, GO:0007166=PMID:7736574, GO:0004716=GO_REF:0000002, GO:0042327=PMID:15082764, GO:0005768=PMID:17182860} Q504U8 Epidermal growth factor receptor protein 20130413 {GO:0005515=IPI, GO:0050730=IMP, GO:0060571=IEA, GO:0005615=NAS, GO:0042802=IPI, GO:0005006=IDA, GO:0016337=IMP, GO:0021795=IEA, GO:0046777=IMP, GO:0003690=NAS, GO:0051015=IDA, GO:0007173=TAS, GO:0000165=NAS, GO:0007411=TAS, GO:0001942=IEA, GO:0004709=NAS, GO:0050679=IDA, GO:0031965=IEA, GO:0030335=IMP, GO:0046982=IDA, GO:0070435=ISS, GO:0030122=TAS, GO:0019903=IPI, GO:0045740=IDA, GO:0051205=TAS, GO:0042059=TAS, GO:0006950=NAS, GO:0001892=IEA, GO:0048546=IEA, GO:0070141=IDA, GO:0001503=NAS, GO:0008543=TAS, GO:0045087=TAS, GO:0005789=IEA, GO:0045121=IDA, GO:0019899=IPI, GO:0010008=IEA, GO:0004888=IDA, GO:0043006=TAS, GO:0051897=IMP, GO:0008284=IDA, GO:0048471=IEA, GO:0005886=IDA, GO:0008283=IDA, GO:0050999=IDA, GO:0005634=IDA, GO:0030139=IEA, GO:0048146=IEA, GO:0007202=TAS, GO:0045739=IDA, GO:0035413=IMP, GO:0045429=IDA, GO:0016323=IDA, GO:0000186=NAS, GO:0005737=IDA, GO:0043406=IDA, GO:0030235=IDA, GO:0007435=IEA, GO:0048011=TAS, GO:0043066=IMP, GO:0042177=IDA, GO:0048015=TAS, GO:0005524=IEA, GO:0000902=IEA, GO:0007165=TAS, GO:0031659=IDA, GO:0000139=IEA, GO:0016020=IDA, GO:0016021=IEA, GO:0004713=TAS, GO:0004714=IEA, GO:0007169=IEA, GO:0007166=IDA, GO:0004716=IEA, GO:0042327=IDA, GO:0005768=IDA} MAPK cascade, activation of MAPKK activity, activation of phospholipase A2 activity by calcium-mediated signaling, activation of phospholipase C activity, axon guidance, cell morphogenesis, cell proliferation, cell surface receptor signaling pathway, cell-cell adhesion, cerebral cortex cell migration, digestive tract morphogenesis, embryonic placenta development, epidermal growth factor receptor signaling pathway, fibroblast growth factor receptor signaling pathway, hair follicle development, innate immune response, morphogenesis of an epithelial fold, negative regulation of apoptotic process, negative regulation of epidermal growth factor receptor signaling pathway, negative regulation of protein catabolic process, neurotrophin TRK receptor signaling pathway, ossification, phosphatidylinositol-mediated signaling, positive regulation of DNA repair, positive regulation of DNA replication, positive regulation of MAP kinase activity, positive regulation of catenin import into nucleus, positive regulation of cell migration, positive regulation of cell proliferation, positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S, positive regulation of epithelial cell proliferation, positive regulation of fibroblast proliferation, positive regulation of nitric oxide biosynthetic process, positive regulation of phosphorylation, positive regulation of protein kinase B signaling cascade, protein autophosphorylation, protein insertion into membrane, regulation of nitric-oxide synthase activity, regulation of peptidyl-tyrosine phosphorylation, response to UV-A, response to stress, salivary gland morphogenesis, signal transduction, transmembrane receptor protein tyrosine kinase signaling pathway AP-2 adaptor complex, Golgi membrane, Shc-EGFR complex, basolateral plasma membrane, cytoplasm, endocytic vesicle, endoplasmic reticulum membrane, endosome, endosome membrane, extracellular space, integral to membrane, membrane, membrane raft, nuclear membrane, nucleus, perinuclear region of cytoplasm, plasma membrane ATP binding, MAP kinase kinase kinase activity, actin filament binding, double-stranded DNA binding, enzyme binding, epidermal growth factor-activated receptor activity, identical protein binding, nitric-oxide synthase regulator activity, protein binding, protein heterodimerization activity, protein phosphatase binding, protein tyrosine kinase activity, receptor signaling protein tyrosine kinase activity, transmembrane receptor protein tyrosine kinase activity, transmembrane signaling receptor activity Human UniProtKB-KW:KW-0067 EGLN1 IntAct UniProtKB {GO:0031545=PMID:11598268, GO:0005515=PMID:15721254, GO:0001666=PMID:16956324, GO:0031543=PMID:16956324, GO:0060711=GO_REF:0000019, GO:0031418=GO_REF:0000037, GO:0005506=GO_REF:0000002, GO:0060412=GO_REF:0000019, GO:0071731=PMID:21601578, GO:0071456=Reactome:REACT_121311, GO:0061418=Reactome:REACT_120815, GO:0045765=GO_REF:0000024, GO:0033554=Reactome:REACT_120956, GO:0005634=GO_REF:0000039, GO:0043433=PMID:16956324, GO:0005829=Reactome:REACT_121242, GO:0060347=GO_REF:0000019, GO:0005737=PMID:12615973, GO:0018401=PMID:11598268, GO:0008270=GO_REF:0000002, GO:0016702=GO_REF:0000037, GO:0032364=PMID:16956324, GO:0055008=GO_REF:0000019} Q9GZT9 Egl nine homolog 1 protein 20130415 {GO:0031545=IDA, GO:0005515=IPI, GO:0001666=IDA, GO:0031543=TAS, GO:0060711=IEA, GO:0031418=IEA, GO:0005506=IEA, GO:0060412=IEA, GO:0071731=IDA, GO:0071456=TAS, GO:0061418=TAS, GO:0045765=ISS, GO:0033554=TAS, GO:0005634=IEA, GO:0043433=IDA, GO:0005829=TAS, GO:0060347=IEA, GO:0005737=IDA, GO:0018401=IDA, GO:0008270=IEA, GO:0016702=IEA, GO:0032364=IDA, GO:0055008=IEA} cardiac muscle tissue morphogenesis, cellular response to hypoxia, cellular response to stress, heart trabecula formation, labyrinthine layer development, negative regulation of sequence-specific DNA binding transcription factor activity, oxygen homeostasis, peptidyl-proline hydroxylation to 4-hydroxy-L-proline, regulation of angiogenesis, regulation of transcription from RNA polymerase II promoter in response to hypoxia, response to hypoxia, response to nitric oxide, ventricular septum morphogenesis cytoplasm, cytosol, nucleus L-ascorbic acid binding, iron ion binding, oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen, peptidyl-proline 4-dioxygenase activity, peptidyl-proline dioxygenase activity, protein binding, zinc ion binding Human UniProtKB:Q13438 EGLN2 LIFEdb UniProtKB {GO:0005515=PMID:22286099, GO:0031545=PMID:11598268, GO:0001666=PMID:11595184, GO:0045732=PMID:11595184, GO:0031418=GO_REF:0000037, GO:0071456=Reactome:REACT_121311, GO:0061418=Reactome:REACT_120815, GO:0033554=Reactome:REACT_120956, GO:0005634=GO_REF:0000054, GO:0001558=PMID:11850811, GO:0008198=PMID:12039559, GO:0043523=PMID:19587290, GO:0018401=PMID:11598268, GO:0019826=PMID:11595184, GO:0016706=PMID:11595184, GO:0005654=Reactome:REACT_120973, GO:0045454=PMID:11595184, GO:0016702=GO_REF:0000037, GO:0030520=PMID:11850811} Q96KS0 Egl nine homolog 2 protein 20100607 {GO:0005515=IPI, GO:0031545=IDA, GO:0001666=IDA, GO:0045732=IDA, GO:0031418=IEA, GO:0071456=TAS, GO:0061418=TAS, GO:0033554=TAS, GO:0005634=IDA, GO:0001558=NAS, GO:0008198=NAS, GO:0043523=IMP, GO:0018401=IDA, GO:0019826=IDA, GO:0016706=IDA, GO:0005654=TAS, GO:0045454=IDA, GO:0016702=IEA, GO:0030520=NAS} cell redox homeostasis, cellular response to hypoxia, cellular response to stress, intracellular estrogen receptor signaling pathway, peptidyl-proline hydroxylation to 4-hydroxy-L-proline, positive regulation of protein catabolic process, regulation of cell growth, regulation of neuron apoptotic process, regulation of transcription from RNA polymerase II promoter in response to hypoxia, response to hypoxia nucleoplasm, nucleus L-ascorbic acid binding, ferrous iron binding, oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors, oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen, oxygen sensor activity, peptidyl-proline 4-dioxygenase activity, protein binding Human EGLN3 Reactome UniProtKB {GO:0031545=PMID:11598268, GO:0005515=PMID:22286099, GO:0001666=PMID:20978507, GO:0031418=GO_REF:0000037, GO:0005506=GO_REF:0000002, GO:0006919=PMID:20978507, GO:0071456=Reactome:REACT_121311, GO:0061418=Reactome:REACT_120815, GO:0006915=PMID:20978507, GO:0033554=Reactome:REACT_120956, GO:0005634=PMID:12615973, GO:0006974=GO_REF:0000037, GO:0005829=Reactome:REACT_121242, GO:0043523=GO_REF:0000024, GO:0005737=PMID:12615973, GO:0018126=PMID:19584355, GO:0042127=PMID:20978507, GO:0018401=PMID:11598268, GO:0016706=GO_REF:0000002, GO:0005654=Reactome:REACT_120973, GO:0016702=GO_REF:0000037} Q9H6Z9 Egl nine homolog 3 protein 20130301 {GO:0031545=IDA, GO:0005515=IPI, GO:0001666=IEP, GO:0031418=IEA, GO:0005506=IEA, GO:0006919=IEP, GO:0071456=TAS, GO:0061418=TAS, GO:0006915=IEP, GO:0033554=TAS, GO:0005634=IDA, GO:0006974=IEA, GO:0005829=TAS, GO:0043523=ISS, GO:0005737=IDA, GO:0018126=IDA, GO:0042127=IEP, GO:0018401=IDA, GO:0016706=IEA, GO:0005654=TAS, GO:0016702=IEA} activation of cysteine-type endopeptidase activity involved in apoptotic process, apoptotic process, cellular response to hypoxia, cellular response to stress, peptidyl-proline hydroxylation to 4-hydroxy-L-proline, protein hydroxylation, regulation of cell proliferation, regulation of neuron apoptotic process, regulation of transcription from RNA polymerase II promoter in response to hypoxia, response to DNA damage stimulus, response to hypoxia cytoplasm, cytosol, nucleoplasm, nucleus L-ascorbic acid binding, iron ion binding, oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors, oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen, peptidyl-proline 4-dioxygenase activity, protein binding Human EGR1 BHF-UCL UniProtKB {GO:0005515=PMID:19057511, GO:0003700=PMID:12560508, GO:0006366=PMID:19057511, GO:0048709=GO_REF:0000019, GO:0019221=Reactome:REACT_25229, GO:0060291=GO_REF:0000019, GO:0042220=GO_REF:0000019, GO:0043525=GO_REF:0000019, GO:0003690=GO_REF:0000019, GO:0072303=GO_REF:0000024, GO:0060337=Reactome:REACT_25162, GO:0051602=GO_REF:0000019, GO:0048169=GO_REF:0000019, GO:0007611=GO_REF:0000019, GO:0031667=GO_REF:0000019, GO:0035035=PMID:20018936, GO:0032869=GO_REF:0000019, GO:0000122=GO_REF:0000019, GO:0030509=GO_REF:0000019, GO:0000979=GO_REF:0000019, GO:0071317=GO_REF:0000019, GO:0071383=GO_REF:0000019, GO:0007623=GO_REF:0000019, GO:0008270=GO_REF:0000002, GO:0005654=Reactome:REACT_25192, GO:0071873=GO_REF:0000019, GO:0045893=PMID:12560508, GO:0008134=GO_REF:0000019, GO:0045471=GO_REF:0000019, GO:0072110=GO_REF:0000024, GO:0005634=PMID:19057511, GO:0071480=GO_REF:0000019, GO:0071372=GO_REF:0000019, GO:0005737=PMID:19057511, GO:0045944=PMID:20018936, GO:0033233=PMID:19057511, GO:0090090=GO_REF:0000019, GO:0070498=PMID:20018936, GO:0071236=GO_REF:0000019, GO:0034465=GO_REF:0000019, GO:0071455=GO_REF:0000019, GO:0071456=GO_REF:0000019, GO:0035690=GO_REF:0000019, GO:0003677=PMID:12560508, GO:0009749=GO_REF:0000019, GO:0043565=PMID:1662794, GO:0001077=GO_REF:0000019, GO:0001975=GO_REF:0000019, GO:0030217=GO_REF:0000019, GO:0071363=GO_REF:0000019, GO:0071504=GO_REF:0000024, GO:0071506=GO_REF:0000024, GO:0071260=GO_REF:0000019, GO:0071320=GO_REF:0000019} P18146 Early growth response protein 1 protein 20110127 {GO:0005515=IPI, GO:0003700=IDA, GO:0006366=IDA, GO:0048709=IEA, GO:0019221=TAS, GO:0060291=IEA, GO:0042220=IEA, GO:0043525=IEA, GO:0003690=IEA, GO:0072303=ISS, GO:0060337=TAS, GO:0051602=IEA, GO:0048169=IEA, GO:0007611=IEA, GO:0031667=IEA, GO:0035035=IPI, GO:0032869=IEA, GO:0000122=IEA, GO:0030509=IEA, GO:0000979=IEA, GO:0071317=IEA, GO:0071383=IEA, GO:0007623=IEA, GO:0008270=IEA, GO:0005654=TAS, GO:0071873=IEA, GO:0045893=IDA, GO:0008134=IEA, GO:0045471=IEA, GO:0072110=ISS, GO:0005634=IDA, GO:0071480=IEA, GO:0071372=IEA, GO:0005737=IDA, GO:0045944=IMP, GO:0033233=IDA, GO:0090090=IEA, GO:0070498=IMP, GO:0071236=IEA, GO:0034465=IEA, GO:0071455=IEA, GO:0071456=IEA, GO:0035690=IEA, GO:0003677=IDA, GO:0009749=IEA, GO:0043565=IDA, GO:0001077=IEA, GO:0001975=IEA, GO:0030217=IEA, GO:0071363=IEA, GO:0071504=ISS, GO:0071506=ISS, GO:0071260=IEA, GO:0071320=IEA} BMP signaling pathway, T cell differentiation, cellular response to antibiotic, cellular response to cAMP, cellular response to drug, cellular response to follicle-stimulating hormone stimulus, cellular response to gamma radiation, cellular response to growth factor stimulus, cellular response to heparin, cellular response to hyperoxia, cellular response to hypoxia, cellular response to insulin stimulus, cellular response to isoquinoline alkaloid, cellular response to mechanical stimulus, cellular response to mycophenolic acid, cellular response to steroid hormone stimulus, circadian rhythm, cytokine-mediated signaling pathway, glomerular mesangial cell proliferation, interleukin-1-mediated signaling pathway, learning or memory, long-term synaptic potentiation, negative regulation of canonical Wnt receptor signaling pathway, negative regulation of transcription from RNA polymerase II promoter, oligodendrocyte differentiation, positive regulation of glomerular metanephric mesangial cell proliferation, positive regulation of neuron apoptotic process, positive regulation of transcription from RNA polymerase II promoter, positive regulation of transcription, DNA-dependent, regulation of long-term neuronal synaptic plasticity, regulation of protein sumoylation, response to amphetamine, response to carbon monoxide, response to cocaine, response to electrical stimulus, response to ethanol, response to glucose stimulus, response to norepinephrine stimulus, response to nutrient levels, transcription from RNA polymerase II promoter, type I interferon-mediated signaling pathway cytoplasm, nucleoplasm, nucleus DNA binding, RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription, RNA polymerase II core promoter sequence-specific DNA binding, double-stranded DNA binding, histone acetyltransferase binding, protein binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, transcription factor binding, zinc ion binding Human EGR2 BHF-UCL UniProtKB {GO:0005515=PMID:14532282, GO:0003700=PMID:14532282, GO:0006366=GO_REF:0000024, GO:0044212=GO_REF:0000024, GO:0016874=GO_REF:0000037, GO:0005634=PMID:14532282, GO:0014037=GO_REF:0000019, GO:0005737=GO_REF:0000024, GO:0030278=GO_REF:0000019, GO:0021660=GO_REF:0000019, GO:0048168=GO_REF:0000019, GO:0035284=GO_REF:0000019, GO:0045944=GO_REF:0000019, GO:0006611=GO_REF:0000024, GO:0007611=GO_REF:0000019, GO:0045444=GO_REF:0000024, GO:0031625=PMID:19651900, GO:0001102=GO_REF:0000024, GO:0032868=GO_REF:0000019, GO:0042552=GO_REF:0000019, GO:0071310=GO_REF:0000019, GO:0016925=GO_REF:0000041, GO:0021666=GO_REF:0000019, GO:0008045=GO_REF:0000019, GO:0007420=PMID:9537424, GO:0003682=GO_REF:0000024, GO:0007422=PMID:9537424, GO:0071837=GO_REF:0000019, GO:0007622=GO_REF:0000019, GO:0008270=GO_REF:0000002, GO:0021612=GO_REF:0000019, GO:0045893=GO_REF:0000024} P11161 E3 SUMO-protein ligase EGR2 protein 20101220 {GO:0005515=IPI, GO:0003700=IDA, GO:0006366=ISS, GO:0044212=ISS, GO:0016874=IEA, GO:0005634=IC, GO:0014037=IEA, GO:0005737=ISS, GO:0030278=IEA, GO:0021660=IEA, GO:0048168=IEA, GO:0035284=IEA, GO:0045944=IEA, GO:0006611=ISS, GO:0007611=IEA, GO:0045444=ISS, GO:0031625=IPI, GO:0001102=ISS, GO:0032868=IEA, GO:0042552=IEA, GO:0071310=IEA, GO:0016925=IEA, GO:0021666=IEA, GO:0008045=IEA, GO:0007420=TAS, GO:0003682=ISS, GO:0007422=TAS, GO:0071837=IEA, GO:0007622=IEA, GO:0008270=IEA, GO:0021612=IEA, GO:0045893=ISS} Schwann cell differentiation, brain development, brain segmentation, cellular response to organic substance, facial nerve structural organization, fat cell differentiation, learning or memory, motor neuron axon guidance, myelination, peripheral nervous system development, positive regulation of transcription from RNA polymerase II promoter, positive regulation of transcription, DNA-dependent, protein export from nucleus, protein sumoylation, regulation of neuronal synaptic plasticity, regulation of ossification, response to insulin stimulus, rhombomere 3 formation, rhombomere 5 formation, rhythmic behavior, transcription from RNA polymerase II promoter cytoplasm, nucleus HMG box domain binding, RNA polymerase II activating transcription factor binding, chromatin binding, ligase activity, protein binding, sequence-specific DNA binding transcription factor activity, transcription regulatory region DNA binding, ubiquitin protein ligase binding, zinc ion binding Human GO:0003700 EGR3 PINC UniProtKB {GO:0007517=PMID:9731539, GO:0003700=PMID:9731539, GO:0007422=GO_REF:0000019, GO:0007623=PMID:9488654, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0007274=GO_REF:0000019, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q06889 Early growth response protein 3 protein 20030904 {GO:0007517=TAS, GO:0003700=TAS, GO:0007422=IEA, GO:0007623=TAS, GO:0005634=IEA, GO:0008270=IEA, GO:0007274=IEA, GO:0003677=IEA, GO:0006351=IEA} circadian rhythm, muscle organ development, neuromuscular synaptic transmission, peripheral nervous system development, transcription, DNA-dependent nucleus DNA binding, sequence-specific DNA binding transcription factor activity, zinc ion binding Human EGR4 PINC UniProtKB {GO:0008284=PMID:1658795, GO:0003700=PMID:1584812, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q05215 Early growth response protein 4 protein 20030904 {GO:0008284=TAS, GO:0003700=NAS, GO:0005634=IEA, GO:0008270=IEA, GO:0003677=IEA, GO:0006351=IEA} positive regulation of cell proliferation, transcription, DNA-dependent nucleus DNA binding, sequence-specific DNA binding transcription factor activity, zinc ion binding Human EHBP1 HPA UniProtKB {GO:0005737=GO_REF:0000052, GO:0016020=GO_REF:0000039} Q8NDI1 EH domain-binding protein 1 protein 20110516 {GO:0005737=IDA, GO:0016020=IEA} cytoplasm, membrane Human EHBP1L1 UniProtKB UniProtKB {GO:0008150=GO_REF:0000015, GO:0003674=GO_REF:0000015, GO:0005575=GO_REF:0000015} Q8N3D4 EH domain-binding protein 1-like protein 1 protein 20101022 {GO:0008150=ND, GO:0003674=ND, GO:0005575=ND} biological_process cellular_component molecular_function Human EHD1 BHF-UCL UniProtKB {GO:0005515=PMID:17233914, GO:0005811=GO_REF:0000024, GO:0042632=GO_REF:0000024, GO:0048471=GO_REF:0000019, GO:0005886=GO_REF:0000039, GO:0032456=PMID:17233914, GO:0005509=GO_REF:0000002, GO:0003924=GO_REF:0000002, GO:0030139=GO_REF:0000019, GO:0005525=GO_REF:0000002, GO:0010886=GO_REF:0000024, GO:0006886=PMID:15020713, GO:0005524=GO_REF:0000037, GO:0006897=GO_REF:0000019, GO:0034383=GO_REF:0000024, GO:0007596=Reactome:REACT_604, GO:0031901=PMID:15020713, GO:0016197=GO_REF:0000019, GO:0051260=PMID:17233914, GO:0031095=GO_REF:0000024, GO:0055038=PMID:15020713, GO:0010008=Reactome:REACT_25249, GO:0005769=GO_REF:0000019} Q9H4M9 EH domain-containing protein 1 protein 20091118 {GO:0005515=IPI, GO:0005811=ISS, GO:0042632=ISS, GO:0048471=IEA, GO:0005886=IEA, GO:0032456=IGI, GO:0005509=IEA, GO:0003924=IEA, GO:0030139=IEA, GO:0005525=IEA, GO:0010886=ISS, GO:0006886=IMP, GO:0005524=IEA, GO:0006897=IEA, GO:0034383=ISS, GO:0007596=TAS, GO:0031901=IDA, GO:0016197=IEA, GO:0051260=IPI, GO:0031095=ISS, GO:0055038=IDA, GO:0010008=TAS, GO:0005769=IEA} blood coagulation, cholesterol homeostasis, endocytic recycling, endocytosis, endosomal transport, intracellular protein transport, low-density lipoprotein particle clearance, positive regulation of cholesterol storage, protein homooligomerization early endosome, early endosome membrane, endocytic vesicle, endosome membrane, lipid particle, perinuclear region of cytoplasm, plasma membrane, platelet dense tubular network membrane, recycling endosome membrane ATP binding, GTP binding, GTPase activity, calcium ion binding, protein binding Human UniProtKB:Q9WVK4 EHD2 Reactome UniProtKB {GO:0005515=PMID:17233914, GO:0048471=GO_REF:0000019, GO:0005886=GO_REF:0000039, GO:0005509=GO_REF:0000002, GO:0019904=GO_REF:0000019, GO:0032456=PMID:17233914, GO:0003924=GO_REF:0000002, GO:0005634=PMID:10673336, GO:0003676=PMID:10673336, GO:0005525=GO_REF:0000002, GO:0005524=GO_REF:0000037, GO:0006897=GO_REF:0000019, GO:0007596=Reactome:REACT_604, GO:0030866=GO_REF:0000019, GO:0055038=PMID:17233914, GO:0010008=Reactome:REACT_25249} Q9NZN4 EH domain-containing protein 2 protein 20101111 {GO:0005515=IPI, GO:0048471=IEA, GO:0005886=IEA, GO:0005509=IEA, GO:0019904=IEA, GO:0032456=IGI, GO:0003924=IEA, GO:0005634=TAS, GO:0003676=TAS, GO:0005525=IEA, GO:0005524=IEA, GO:0006897=IEA, GO:0007596=TAS, GO:0030866=IEA, GO:0055038=IDA, GO:0010008=TAS} blood coagulation, cortical actin cytoskeleton organization, endocytic recycling, endocytosis endosome membrane, nucleus, perinuclear region of cytoplasm, plasma membrane, recycling endosome membrane ATP binding, GTP binding, GTPase activity, calcium ion binding, nucleic acid binding, protein binding, protein domain specific binding Human EHD3 Reactome UniProtKB {GO:0005515=PMID:17233914, GO:0048471=GO_REF:0000019, GO:0005886=GO_REF:0000039, GO:0072661=PMID:20489164, GO:0005509=GO_REF:0000002, GO:0032456=PMID:17233914, GO:0003924=GO_REF:0000002, GO:0005634=PMID:10673336, GO:0030139=GO_REF:0000019, GO:0005525=GO_REF:0000002, GO:0003676=PMID:10673336, GO:0005524=GO_REF:0000037, GO:0005737=GO_REF:0000024, GO:0007596=Reactome:REACT_604, GO:0051260=PMID:17233914, GO:0086036=PMID:20489164, GO:0055038=PMID:17233914, GO:0010008=Reactome:REACT_25249} Q9NZN3 EH domain-containing protein 3 protein 20101111 {GO:0005515=IPI, GO:0048471=IEA, GO:0005886=IEA, GO:0072661=IGI, GO:0005509=IEA, GO:0032456=IDA, GO:0003924=IEA, GO:0005634=TAS, GO:0030139=IEA, GO:0005525=IEA, GO:0003676=TAS, GO:0005524=IEA, GO:0005737=ISS, GO:0007596=TAS, GO:0051260=IPI, GO:0086036=IGI, GO:0055038=IDA, GO:0010008=TAS} blood coagulation, endocytic recycling, protein homooligomerization, protein targeting to plasma membrane, regulation of cardiac muscle cell membrane potential cytoplasm, endocytic vesicle, endosome membrane, nucleus, perinuclear region of cytoplasm, plasma membrane, recycling endosome membrane ATP binding, GTP binding, GTPase activity, calcium ion binding, nucleic acid binding, protein binding Human EHD4 LIFEdb UniProtKB {GO:0005515=PMID:17233914, GO:0006907=GO_REF:0000019, GO:0048471=GO_REF:0000019, GO:0005886=GO_REF:0000019, GO:0005783=GO_REF:0000054, GO:0032456=PMID:17233914, GO:0005509=GO_REF:0000002, GO:0003924=GO_REF:0000002, GO:0050731=GO_REF:0000019, GO:0005634=PMID:10673336, GO:0003676=PMID:10673336, GO:0005525=GO_REF:0000002, GO:0005524=GO_REF:0000037, GO:0071363=GO_REF:0000019, GO:0030100=GO_REF:0000019, GO:0031901=GO_REF:0000039, GO:0051260=PMID:17233914, GO:0055038=PMID:17233914} Q9H223 EH domain-containing protein 4 protein 20100607 {GO:0005515=IPI, GO:0006907=IEA, GO:0048471=IEA, GO:0005886=IEA, GO:0005783=IDA, GO:0032456=IGI, GO:0005509=IEA, GO:0003924=IEA, GO:0050731=IEA, GO:0005634=TAS, GO:0003676=TAS, GO:0005525=IEA, GO:0005524=IEA, GO:0071363=IEA, GO:0030100=IEA, GO:0031901=IEA, GO:0051260=IPI, GO:0055038=IDA} cellular response to growth factor stimulus, endocytic recycling, pinocytosis, positive regulation of peptidyl-tyrosine phosphorylation, protein homooligomerization, regulation of endocytosis early endosome membrane, endoplasmic reticulum, nucleus, perinuclear region of cytoplasm, plasma membrane, recycling endosome membrane ATP binding, GTP binding, GTPase activity, calcium ion binding, nucleic acid binding, protein binding Human EHF UniProtKB UniProtKB {GO:0043565=GO_REF:0000002, GO:0003700=PMID:10644770, GO:0008283=PMID:10644770, GO:0030855=PMID:10644770, GO:0007275=PMID:10644770, GO:0005634=PMID:10644770, GO:0045893=PMID:10644770, GO:0003677=PMID:10644770, GO:0006351=GO_REF:0000037} Q9NZC4 ETS homologous factor protein 20061130 {GO:0043565=IEA, GO:0003700=IDA, GO:0008283=TAS, GO:0030855=IEP, GO:0007275=TAS, GO:0005634=IC, GO:0045893=IDA, GO:0003677=IDA, GO:0006351=IEA} cell proliferation, epithelial cell differentiation, multicellular organismal development, positive regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus DNA binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity Human EHHADH HPA UniProtKB {GO:0050662=GO_REF:0000002, GO:0006635=PMID:8188243, GO:0005730=GO_REF:0000052, GO:0005102=PMID:20178365, GO:0003857=PMID:8188243, GO:0005634=GO_REF:0000052, GO:0003824=GO_REF:0000002, GO:0043231=GO_REF:0000052, GO:0005829=GO_REF:0000019, GO:0005739=GO_REF:0000019, GO:0005737=GO_REF:0000052, GO:0004165=GO_REF:0000003, GO:0006475=PMID:20167786, GO:0019899=PMID:16781659, GO:0004300=PMID:8188243, GO:0005777=PMID:8188243} Q08426 Peroxisomal bifunctional enzyme protein 20110516 {GO:0050662=IEA, GO:0006635=NAS, GO:0005730=IDA, GO:0005102=IPI, GO:0003857=NAS, GO:0005634=IDA, GO:0003824=IEA, GO:0043231=IDA, GO:0005829=IEA, GO:0005739=IEA, GO:0005737=IDA, GO:0004165=IEA, GO:0006475=IDA, GO:0019899=IPI, GO:0004300=NAS, GO:0005777=NAS} fatty acid beta-oxidation, internal protein amino acid acetylation cytoplasm, cytosol, intracellular membrane-bounded organelle, mitochondrion, nucleolus, nucleus, peroxisome 3-hydroxyacyl-CoA dehydrogenase activity, catalytic activity, coenzyme binding, dodecenoyl-CoA delta-isomerase activity, enoyl-CoA hydratase activity, enzyme binding, receptor binding Human EHMT1 IntAct UniProtKB {GO:0005515=PMID:21131967, GO:0005694=GO_REF:0000039, GO:0016571=PMID:12004135, GO:0008168=PMID:12004135, GO:0018027=PMID:20118233, GO:0005634=GO_REF:0000024, GO:0000122=GO_REF:0000019, GO:0009790=GO_REF:0000024, GO:0016279=PMID:20118233, GO:0018026=GO_REF:0000024, GO:0018024=PMID:12004135, GO:0006306=GO_REF:0000024, GO:0002039=PMID:20118233, GO:0046974=GO_REF:0000024, GO:0008270=GO_REF:0000002, GO:0045892=GO_REF:0000024, GO:0046976=GO_REF:0000024, GO:0016568=PMID:12004135} Q9H9B1 Histone-lysine N-methyltransferase EHMT1 protein 20130415 {GO:0005515=IPI, GO:0005694=IEA, GO:0016571=IDA, GO:0008168=IDA, GO:0018027=IDA, GO:0005634=ISS, GO:0000122=IEA, GO:0009790=ISS, GO:0016279=IDA, GO:0018026=ISS, GO:0018024=IDA, GO:0006306=ISS, GO:0002039=IPI, GO:0046974=ISS, GO:0008270=IEA, GO:0045892=ISS, GO:0046976=ISS, GO:0016568=IDA} DNA methylation, chromatin modification, embryo development, histone methylation, negative regulation of transcription from RNA polymerase II promoter, negative regulation of transcription, DNA-dependent, peptidyl-lysine dimethylation, peptidyl-lysine monomethylation chromosome, nucleus histone methyltransferase activity (H3-K27 specific), histone methyltransferase activity (H3-K9 specific), histone-lysine N-methyltransferase activity, methyltransferase activity, p53 binding, protein binding, protein-lysine N-methyltransferase activity, zinc ion binding Human UniProtKB:Q04207 EHMT2 IntAct UniProtKB {GO:0005515=PMID:17636019, GO:0000239=GO_REF:0000019, GO:0005694=GO_REF:0000039, GO:0016571=PMID:22387026, GO:0007286=GO_REF:0000019, GO:0010424=GO_REF:0000019, GO:0018027=PMID:20118233, GO:0005634=GO_REF:0000024, GO:0000122=GO_REF:0000019, GO:0016279=PMID:20118233, GO:0018024=PMID:22387026, GO:0006306=GO_REF:0000024, GO:0009566=GO_REF:0000019, GO:0002039=PMID:20118233, GO:0035265=GO_REF:0000019, GO:0046974=GO_REF:0000024, GO:0008270=GO_REF:0000002, GO:0007130=GO_REF:0000019, GO:0006275=PMID:22387026, GO:0046976=GO_REF:0000024} Q96KQ7 Histone-lysine N-methyltransferase EHMT2 protein 20130415 {GO:0005515=IPI, GO:0000239=IEA, GO:0005694=IEA, GO:0016571=IMP, GO:0007286=IEA, GO:0010424=IEA, GO:0018027=IDA, GO:0005634=ISS, GO:0000122=IEA, GO:0016279=IDA, GO:0018024=IMP, GO:0006306=ISS, GO:0009566=IEA, GO:0002039=IPI, GO:0035265=IEA, GO:0046974=ISS, GO:0008270=IEA, GO:0007130=IEA, GO:0006275=IMP, GO:0046976=ISS} DNA methylation, DNA methylation on cytosine within a CG sequence, fertilization, histone methylation, negative regulation of transcription from RNA polymerase II promoter, organ growth, pachytene, peptidyl-lysine dimethylation, regulation of DNA replication, spermatid development, synaptonemal complex assembly chromosome, nucleus histone methyltransferase activity (H3-K27 specific), histone methyltransferase activity (H3-K9 specific), histone-lysine N-methyltransferase activity, p53 binding, protein binding, protein-lysine N-methyltransferase activity, zinc ion binding Human UniProtKB:Q9NQX1 EI24 MGI UniProtKB {GO:0030308=PMID:10594026, GO:0031965=GO_REF:0000039, GO:0042493=GO_REF:0000019, GO:0005789=GO_REF:0000039, GO:0006914=GO_REF:0000037, GO:0006915=GO_REF:0000037, GO:0016021=GO_REF:0000037, GO:0006917=GO_REF:0000019} O14681 Etoposide-induced protein 2.4 homolog protein 20080903 {GO:0030308=IDA, GO:0031965=IEA, GO:0042493=IEA, GO:0005789=IEA, GO:0006914=IEA, GO:0006915=IEA, GO:0016021=IEA, GO:0006917=IEA} apoptotic process, autophagy, induction of apoptosis, negative regulation of cell growth, response to drug endoplasmic reticulum membrane, integral to membrane, nuclear membrane Human EID1 GOC UniProtKB {GO:0035035=PMID:11073990, GO:0005515=PMID:18557765, GO:0005737=GO_REF:0000039, GO:0007049=GO_REF:0000037, GO:0035034=PMID:11073990, GO:0003714=GO_REF:0000024, GO:0035065=PMID:11073990, GO:0005634=PMID:11073990, GO:0000122=PMID:11073990, GO:0045892=PMID:11073990, GO:0030154=PMID:11073989, GO:0006351=GO_REF:0000037} Q9Y6B2 EP300-interacting inhibitor of differentiation 1 protein 20130413 {GO:0035035=IDA, GO:0005515=IPI, GO:0005737=IEA, GO:0007049=IEA, GO:0035034=IDA, GO:0003714=ISS, GO:0035065=IDA, GO:0005634=IPI, GO:0000122=IDA, GO:0045892=IDA, GO:0030154=IDA, GO:0006351=IEA} cell cycle, cell differentiation, negative regulation of transcription from RNA polymerase II promoter, negative regulation of transcription, DNA-dependent, regulation of histone acetylation, transcription, DNA-dependent cytoplasm, nucleus histone acetyltransferase binding, histone acetyltransferase regulator activity, protein binding, transcription corepressor activity Human EID2 HPA UniProtKB {GO:0005515=PMID:15970276, GO:0005730=GO_REF:0000052, GO:0046332=PMID:14612439, GO:0005634=GO_REF:0000052, GO:0006351=GO_REF:0000037, GO:0030154=GO_REF:0000037, GO:0005622=PMID:14612439, GO:0007183=PMID:14612439, GO:0007517=GO_REF:0000037, GO:0007181=PMID:14612439, GO:0042127=PMID:14612439, GO:0017015=PMID:14612439, GO:0045892=PMID:14612439, GO:0030512=PMID:14612439} Q8N6I1 EP300-interacting inhibitor of differentiation 2 protein 20111111 {GO:0005515=IPI, GO:0005730=IDA, GO:0046332=IDA, GO:0005634=IDA, GO:0006351=IEA, GO:0030154=IEA, GO:0005622=IC, GO:0007183=IDA, GO:0007517=IEA, GO:0007181=IDA, GO:0042127=IDA, GO:0017015=IDA, GO:0045892=IDA, GO:0030512=IDA} SMAD protein complex assembly, cell differentiation, muscle organ development, negative regulation of transcription, DNA-dependent, negative regulation of transforming growth factor beta receptor signaling pathway, regulation of cell proliferation, regulation of transforming growth factor beta receptor signaling pathway, transcription, DNA-dependent, transforming growth factor beta receptor complex assembly intracellular, nucleolus, nucleus SMAD binding, protein binding NOT Human EID2B UniProtKB UniProtKB {GO:0006355=GO_REF:0000037, GO:0007517=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0030154=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q96D98 EP300-interacting inhibitor of differentiation 2B protein 20130413 {GO:0006355=IEA, GO:0007517=IEA, GO:0005634=IEA, GO:0030154=IEA, GO:0006351=IEA} cell differentiation, muscle organ development, regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus Human UniProtKB-SubCell:SL-0191 EID3 IntAct UniProtKB {GO:0005515=PMID:21364888, GO:0005737=GO_REF:0000039, GO:0000781=GO_REF:0000039, GO:0006355=GO_REF:0000037, GO:0006281=GO_REF:0000037, GO:0030915=PMID:18086888, GO:0005634=GO_REF:0000039, GO:0006310=GO_REF:0000037, GO:0006351=GO_REF:0000037, GO:0042802=PMID:15970276} Q8N140 EP300-interacting inhibitor of differentiation 3 protein 20130415 {GO:0005515=IPI, GO:0005737=IEA, GO:0000781=IEA, GO:0006355=IEA, GO:0006281=IEA, GO:0030915=IDA, GO:0005634=IEA, GO:0006310=IEA, GO:0006351=IEA, GO:0042802=IPI} DNA recombination, DNA repair, regulation of transcription, DNA-dependent, transcription, DNA-dependent Smc5-Smc6 complex, chromosome, telomeric region, cytoplasm, nucleus identical protein binding, protein binding Human UniProtKB:Q8N140 EIF1 PINC UniProtKB {GO:0005737=PMID:10347211, GO:0006446=PMID:10347211, GO:0006950=PMID:10347211, GO:0003743=PMID:10347211, GO:0008135=PMID:10347211, GO:0006413=GO_REF:0000029} P41567 Eukaryotic translation initiation factor 1 protein 20030904 {GO:0005737=TAS, GO:0006446=TAS, GO:0006950=NAS, GO:0003743=NAS, GO:0008135=TAS, GO:0006413=NAS} regulation of translational initiation, response to stress, translational initiation cytoplasm translation factor activity, nucleic acid binding, translation initiation factor activity Human EIF1AD UniProtKB UniProtKB {GO:0003743=GO_REF:0000002, GO:0005634=GO_REF:0000039} Q8N9N8 Probable RNA-binding protein EIF1AD protein 20130413 {GO:0003743=IEA, GO:0005634=IEA} nucleus translation initiation factor activity Human UniProtKB-SubCell:SL-0191 EIF1AX Reactome UniProtKB {GO:0010467=Reactome:REACT_71, GO:0003743=GO_REF:0000037, GO:0044267=Reactome:REACT_17015, GO:0006412=Reactome:REACT_1014, GO:0006413=Reactome:REACT_2159, GO:0008135=PMID:8106356, GO:0005829=Reactome:REACT_1904} P47813 Eukaryotic translation initiation factor 1A, X-chromosomal protein 20130213 {GO:0010467=TAS, GO:0003743=IEA, GO:0044267=TAS, GO:0006412=TAS, GO:0006413=TAS, GO:0008135=TAS, GO:0005829=TAS} cellular protein metabolic process, gene expression, translation, translational initiation cytosol translation factor activity, nucleic acid binding, translation initiation factor activity Human EIF1AY IntAct UniProtKB {GO:0005515=PMID:12569173, GO:0003743=GO_REF:0000037} O14602 Eukaryotic translation initiation factor 1A, Y-chromosomal protein 20130415 {GO:0005515=IPI, GO:0003743=IEA} protein binding, translation initiation factor activity Human UniProtKB:O60841 EIF1B UniProtKB UniProtKB {GO:0006446=PMID:7904817, GO:0003743=GO_REF:0000037, GO:0005575=GO_REF:0000015} O60739 Eukaryotic translation initiation factor 1b protein 20080924 {GO:0006446=NAS, GO:0003743=IEA, GO:0005575=ND} regulation of translational initiation cellular_component translation initiation factor activity Human EIF2A UniProtKB UniProtKB {GO:0005515=PMID:18816594, GO:0005850=PMID:12133843, GO:0005737=PMID:12133843, GO:0000049=PMID:12133843, GO:0032933=GO_REF:0000019, GO:0042255=PMID:12133843, GO:0043022=PMID:12133843, GO:0003743=PMID:12133843, GO:0009967=GO_REF:0000019, GO:0006468=GO_REF:0000019, GO:0006417=PMID:12133843} Q9BY44 Eukaryotic translation initiation factor 2A protein 20120223 {GO:0005515=IPI, GO:0005850=IDA, GO:0005737=IDA, GO:0000049=IMP, GO:0032933=IEA, GO:0042255=IMP, GO:0043022=IMP, GO:0003743=IMP, GO:0009967=IEA, GO:0006468=IEA, GO:0006417=IMP} SREBP signaling pathway, positive regulation of signal transduction, protein phosphorylation, regulation of translation, ribosome assembly cytoplasm, eukaryotic translation initiation factor 2 complex protein binding, ribosome binding, tRNA binding, translation initiation factor activity Human UniProtKB:Q14899 EIF2AK1 UniProtKB UniProtKB {GO:0008285=GO_REF:0000019, GO:0006950=PMID:11036079, GO:0003743=GO_REF:0000038, GO:0010999=GO_REF:0000019, GO:0005524=GO_REF:0000037, GO:0042803=GO_REF:0000024, GO:0005737=GO_REF:0000039, GO:0045993=PMID:11036079, GO:0009605=PMID:11036079, GO:0046777=GO_REF:0000024, GO:0004674=GO_REF:0000002, GO:0046986=GO_REF:0000024, GO:0046501=GO_REF:0000019, GO:0004694=PMID:11036079, GO:0020037=GO_REF:0000024} Q9BQI3 Eukaryotic translation initiation factor 2-alpha kinase 1 protein 20041006 {GO:0008285=IEA, GO:0006950=IEP, GO:0003743=IEA, GO:0010999=IEA, GO:0005524=IEA, GO:0042803=ISS, GO:0005737=IEA, GO:0045993=NAS, GO:0009605=IEP, GO:0046777=ISS, GO:0004674=IEA, GO:0046986=ISS, GO:0046501=IEA, GO:0004694=IDA, GO:0020037=ISS} negative regulation of cell proliferation, negative regulation of hemoglobin biosynthetic process, negative regulation of translational initiation by iron, protein autophosphorylation, protoporphyrinogen IX metabolic process, regulation of eIF2 alpha phosphorylation by heme, response to external stimulus, response to stress cytoplasm ATP binding, eukaryotic translation initiation factor 2alpha kinase activity, heme binding, protein homodimerization activity, protein serine/threonine kinase activity, translation initiation factor activity Human UniProtKB:Q9Z2R9 EIF2AK2 IntAct UniProtKB {GO:0005515=PMID:23455922, GO:0003725=GO_REF:0000019, GO:0033689=PMID:16216244, GO:0008285=PMID:1351683, GO:0019054=Reactome:REACT_6222, GO:0008601=PMID:10866685, GO:0019058=Reactome:REACT_6167, GO:0006926=GO_REF:0000019, GO:0006412=GO_REF:0000019, GO:0005524=GO_REF:0000037, GO:0005829=Reactome:REACT_6186, GO:0030968=GO_REF:0000019, GO:0051607=GO_REF:0000037, GO:0004672=GO_REF:0000019, GO:0046777=PMID:16216244, GO:0004674=PMID:1695551, GO:0019048=Reactome:REACT_6323, GO:0030683=Reactome:REACT_6350, GO:0006468=PMID:1695551, GO:0004715=GO_REF:0000003, GO:0004694=PMID:10866685} P19525 Interferon-induced, double-stranded RNA-activated protein kinase protein 20130415 {GO:0005515=IPI, GO:0003725=IEA, GO:0033689=IMP, GO:0008285=TAS, GO:0019054=TAS, GO:0008601=TAS, GO:0019058=TAS, GO:0006926=IEA, GO:0006412=IEA, GO:0005524=IEA, GO:0005829=TAS, GO:0030968=IEA, GO:0051607=IEA, GO:0004672=IEA, GO:0046777=IMP, GO:0004674=TAS, GO:0019048=TAS, GO:0030683=TAS, GO:0006468=TAS, GO:0004715=IEA, GO:0004694=TAS} defense response to virus, endoplasmic reticulum unfolded protein response, evasion or tolerance by virus of host immune response, modulation by virus of host cellular process, negative regulation of cell proliferation, negative regulation of osteoblast proliferation, protein autophosphorylation, protein phosphorylation, translation, viral infectious cycle, virus-host interaction, virus-infected cell apoptotic process cytosol ATP binding, double-stranded RNA binding, eukaryotic translation initiation factor 2alpha kinase activity, non-membrane spanning protein tyrosine kinase activity, protein binding, protein kinase activity, protein phosphatase type 2A regulator activity, protein serine/threonine kinase activity Human UniProtKB:Q7L2E3 EIF2AK3 BHF-UCL UniProtKB {GO:0017148=PMID:12086964, GO:0005515=PMID:11907036, GO:0032055=GO_REF:0000019, GO:0034976=PMID:19061639, GO:0019722=GO_REF:0000024, GO:0006983=PMID:10677345, GO:0005783=GO_REF:0000024, GO:0006926=GO_REF:0000019, GO:0030282=GO_REF:0000024, GO:0006412=GO_REF:0000019, GO:0042802=PMID:11907036, GO:0030968=PMID:19816510, GO:0032092=GO_REF:0000019, GO:0005737=GO_REF:0000024, GO:0032933=GO_REF:0000019, GO:0046777=PMID:12086964, GO:0002063=GO_REF:0000024, GO:0045444=GO_REF:0000019, GO:0051260=PMID:11907036, GO:0031642=GO_REF:0000024, GO:0006919=GO_REF:0000024, GO:0019903=PMID:22169477, GO:0009967=GO_REF:0000019, GO:0019217=GO_REF:0000019, GO:0005524=GO_REF:0000037, GO:0032057=PMID:19816510, GO:0001501=GO_REF:0000024, GO:0004672=PMID:10026192, GO:0007595=GO_REF:0000019, GO:0001503=PMID:12086964, GO:0031016=GO_REF:0000019, GO:0004674=Reactome:REACT_18275, GO:0031018=PMID:12086964, GO:0005789=Reactome:REACT_18413, GO:0006468=GO_REF:0000024, GO:0048009=GO_REF:0000024, GO:0016021=GO_REF:0000037, GO:0006987=Reactome:REACT_18277, GO:0044267=Reactome:REACT_17015, GO:0030073=GO_REF:0000024, GO:0007029=GO_REF:0000024, GO:0004694=PMID:12086964} Q9NZJ5 Eukaryotic translation initiation factor 2-alpha kinase 3 protein 20100107 {GO:0017148=TAS, GO:0005515=IPI, GO:0032055=IEA, GO:0034976=IMP, GO:0019722=ISS, GO:0006983=IDA, GO:0005783=ISS, GO:0006926=IEA, GO:0030282=ISS, GO:0006412=IEA, GO:0042802=IPI, GO:0030968=TAS, GO:0032092=IEA, GO:0005737=ISS, GO:0032933=IEA, GO:0046777=IMP, GO:0002063=ISS, GO:0045444=IEA, GO:0051260=IMP, GO:0031642=ISS, GO:0006919=ISS, GO:0019903=IPI, GO:0009967=IEA, GO:0019217=IEA, GO:0005524=IEA, GO:0032057=TAS, GO:0001501=ISS, GO:0004672=TAS, GO:0007595=IEA, GO:0001503=IMP, GO:0031016=IEA, GO:0004674=TAS, GO:0031018=IMP, GO:0005789=TAS, GO:0006468=ISS, GO:0048009=ISS, GO:0016021=IEA, GO:0006987=TAS, GO:0044267=TAS, GO:0030073=ISS, GO:0007029=ISS, GO:0004694=IMP} ER overload response, SREBP signaling pathway, activation of cysteine-type endopeptidase activity involved in apoptotic process, activation of signaling protein activity involved in unfolded protein response, bone mineralization, calcium-mediated signaling, cellular protein metabolic process, chondrocyte development, endocrine pancreas development, endoplasmic reticulum organization, endoplasmic reticulum unfolded protein response, fat cell differentiation, insulin secretion, insulin-like growth factor receptor signaling pathway, lactation, negative regulation of myelination, negative regulation of translation, negative regulation of translation in response to stress, negative regulation of translational initiation in response to stress, ossification, pancreas development, positive regulation of protein binding, positive regulation of signal transduction, protein autophosphorylation, protein homooligomerization, protein phosphorylation, regulation of fatty acid metabolic process, response to endoplasmic reticulum stress, skeletal system development, translation, virus-infected cell apoptotic process cytoplasm, endoplasmic reticulum, endoplasmic reticulum membrane, integral to membrane ATP binding, eukaryotic translation initiation factor 2alpha kinase activity, identical protein binding, protein binding, protein kinase activity, protein phosphatase binding, protein serine/threonine kinase activity Human EIF2AK4 UniProtKB UniProtKB {GO:0005622=GO_REF:0000029, GO:0017148=GO_REF:0000019, GO:0043558=GO_REF:0000019, GO:0022626=GO_REF:0000024, GO:0004674=GO_REF:0000024, GO:0006446=GO_REF:0000024, GO:0006468=GO_REF:0000024, GO:0005524=GO_REF:0000037, GO:0042803=GO_REF:0000002, GO:0004694=PMID:10504407, GO:0030968=GO_REF:0000019, GO:0009267=GO_REF:0000019} Q9P2K8 Eukaryotic translation initiation factor 2-alpha kinase 4 protein 20051108 {GO:0005622=NAS, GO:0017148=IEA, GO:0043558=IEA, GO:0022626=ISS, GO:0004674=ISS, GO:0006446=ISS, GO:0006468=ISS, GO:0005524=IEA, GO:0042803=IEA, GO:0004694=ISS, GO:0030968=IEA, GO:0009267=IEA} cellular response to starvation, endoplasmic reticulum unfolded protein response, negative regulation of translation, protein phosphorylation, regulation of translational initiation, regulation of translational initiation in response to stress cytosolic ribosome, intracellular ATP binding, eukaryotic translation initiation factor 2alpha kinase activity, protein homodimerization activity, protein serine/threonine kinase activity Human UniProtKB:Q9QZ05 EIF2B1 IntAct UniProtKB {GO:0005515=PMID:9235896, GO:0005851=PMID:11323413, GO:0010467=Reactome:REACT_71, GO:0051716=PMID:8626696, GO:0005886=PMID:9235896, GO:0009408=GO_REF:0000024, GO:0043434=GO_REF:0000024, GO:0003743=PMID:16289705, GO:0005525=GO_REF:0000019, GO:0006412=Reactome:REACT_1014, GO:0006413=Reactome:REACT_2159, GO:0005829=Reactome:REACT_1401, GO:0009749=GO_REF:0000024, GO:0005085=PMID:11323413, GO:0032057=GO_REF:0000019, GO:0005737=PMID:9235896, GO:0016020=PMID:9235896, GO:0019509=GO_REF:0000033, GO:0014003=PMID:15217090, GO:0006446=GO_REF:0000033, GO:0019003=GO_REF:0000019, GO:0044267=Reactome:REACT_17015, GO:0044237=GO_REF:0000002, GO:0046523=GO_REF:0000033} Q14232 Translation initiation factor eIF-2B subunit alpha protein 20130415 {GO:0005515=IPI, GO:0005851=IDA, GO:0010467=TAS, GO:0051716=IDA, GO:0005886=IDA, GO:0009408=ISS, GO:0043434=ISS, GO:0003743=IDA, GO:0005525=IEA, GO:0006412=TAS, GO:0006413=TAS, GO:0005829=TAS, GO:0009749=ISS, GO:0005085=IDA, GO:0032057=IEA, GO:0005737=IDA, GO:0016020=IDA, GO:0019509=IBA, GO:0014003=IMP, GO:0006446=IBA, GO:0019003=IEA, GO:0044267=TAS, GO:0044237=IEA, GO:0046523=IBA} L-methionine salvage from methylthioadenosine, cellular metabolic process, cellular protein metabolic process, cellular response to stimulus, gene expression, negative regulation of translational initiation in response to stress, oligodendrocyte development, regulation of translational initiation, response to glucose stimulus, response to heat, response to peptide hormone stimulus, translation, translational initiation cytoplasm, cytosol, eukaryotic translation initiation factor 2B complex, membrane, plasma membrane GDP binding, GTP binding, S-methyl-5-thioribose-1-phosphate isomerase activity, guanyl-nucleotide exchange factor activity, protein binding, translation initiation factor activity Human UniProtKB:Q01338 EIF2B2 Reactome UniProtKB {GO:0005851=PMID:11323413, GO:0005515=PMID:15060152, GO:0010467=Reactome:REACT_71, GO:0051716=PMID:8626696, GO:0009408=GO_REF:0000024, GO:0042552=PMID:14566705, GO:0003743=PMID:16289705, GO:0043434=GO_REF:0000024, GO:0007417=PMID:15776425, GO:0005525=PMID:11323413, GO:0006412=Reactome:REACT_1014, GO:0005524=PMID:11323413, GO:0006413=Reactome:REACT_2159, GO:0005829=Reactome:REACT_1401, GO:0009749=GO_REF:0000024, GO:0005085=PMID:11323413, GO:0001541=PMID:15507143, GO:0005737=PMID:11323413, GO:0019509=GO_REF:0000033, GO:0014003=PMID:15217090, GO:0006446=PMID:15060152, GO:0044267=Reactome:REACT_17015, GO:0044237=GO_REF:0000002, GO:0046523=GO_REF:0000033} P49770 Translation initiation factor eIF-2B subunit beta protein 20130213 {GO:0005851=IDA, GO:0005515=IPI, GO:0010467=TAS, GO:0051716=IDA, GO:0009408=ISS, GO:0042552=IMP, GO:0003743=IDA, GO:0043434=ISS, GO:0007417=IMP, GO:0005525=IDA, GO:0006412=TAS, GO:0005524=IDA, GO:0006413=TAS, GO:0005829=TAS, GO:0009749=ISS, GO:0005085=IDA, GO:0001541=IMP, GO:0005737=IDA, GO:0019509=IBA, GO:0014003=IMP, GO:0006446=TAS, GO:0044267=TAS, GO:0044237=IEA, GO:0046523=IBA} L-methionine salvage from methylthioadenosine, cellular metabolic process, cellular protein metabolic process, cellular response to stimulus, central nervous system development, gene expression, myelination, oligodendrocyte development, ovarian follicle development, regulation of translational initiation, response to glucose stimulus, response to heat, response to peptide hormone stimulus, translation, translational initiation cytoplasm, cytosol, eukaryotic translation initiation factor 2B complex ATP binding, GTP binding, S-methyl-5-thioribose-1-phosphate isomerase activity, guanyl-nucleotide exchange factor activity, protein binding, translation initiation factor activity Human EIF2B3 Reactome UniProtKB {GO:0005515=PMID:15060152, GO:0005851=PMID:11323413, GO:0010467=Reactome:REACT_71, GO:0051716=PMID:8626696, GO:0009408=GO_REF:0000024, GO:0009058=GO_REF:0000002, GO:0016779=GO_REF:0000002, GO:0003743=PMID:16289705, GO:0043434=GO_REF:0000024, GO:0006412=Reactome:REACT_1014, GO:0006413=Reactome:REACT_2159, GO:0005829=Reactome:REACT_1401, GO:0009749=GO_REF:0000024, GO:0005085=PMID:11323413, GO:0032057=GO_REF:0000024, GO:0005737=PMID:11323413, GO:0014003=PMID:15217090, GO:0044267=Reactome:REACT_17015, GO:0016740=GO_REF:0000002, GO:0008135=PMID:10900014} Q9NR50 Translation initiation factor eIF-2B subunit gamma protein 20130213 {GO:0005515=IPI, GO:0005851=IDA, GO:0010467=TAS, GO:0051716=IDA, GO:0009408=ISS, GO:0009058=IEA, GO:0016779=IEA, GO:0003743=IDA, GO:0043434=ISS, GO:0006412=TAS, GO:0006413=TAS, GO:0005829=TAS, GO:0009749=ISS, GO:0005085=IDA, GO:0032057=ISS, GO:0005737=IDA, GO:0014003=IMP, GO:0044267=TAS, GO:0016740=IEA, GO:0008135=IDA} biosynthetic process, cellular protein metabolic process, cellular response to stimulus, gene expression, negative regulation of translational initiation in response to stress, oligodendrocyte development, response to glucose stimulus, response to heat, response to peptide hormone stimulus, translation, translational initiation cytoplasm, cytosol, eukaryotic translation initiation factor 2B complex guanyl-nucleotide exchange factor activity, nucleotidyltransferase activity, protein binding, transferase activity, translation factor activity, nucleic acid binding, translation initiation factor activity Human EIF2B4 Reactome UniProtKB {GO:0005515=PMID:15060152, GO:0010467=Reactome:REACT_71, GO:0051716=PMID:8626696, GO:0009408=GO_REF:0000024, GO:0003743=PMID:16289705, GO:0043434=GO_REF:0000024, GO:0006412=Reactome:REACT_1014, GO:0006413=Reactome:REACT_2159, GO:0005829=Reactome:REACT_1401, GO:0005085=PMID:11323413, GO:0005737=PMID:11323413, GO:0001541=PMID:15507143, GO:0019509=GO_REF:0000033, GO:0045947=GO_REF:0000033, GO:0044237=GO_REF:0000002, GO:0005851=PMID:11323413, GO:0042552=PMID:14566705, GO:0006417=PMID:12556349, GO:0009749=GO_REF:0000024, GO:0032057=GO_REF:0000024, GO:0014003=PMID:15217090, GO:0006446=GO_REF:0000033, GO:0031369=GO_REF:0000024, GO:0044267=Reactome:REACT_17015, GO:0046523=GO_REF:0000033} Q9UI10 Translation initiation factor eIF-2B subunit delta protein 20130213 {GO:0005515=IPI, GO:0010467=TAS, GO:0051716=IDA, GO:0009408=ISS, GO:0003743=IDA, GO:0043434=ISS, GO:0006412=TAS, GO:0006413=TAS, GO:0005829=TAS, GO:0005085=IDA, GO:0005737=IDA, GO:0001541=IMP, GO:0019509=IBA, GO:0045947=IBA, GO:0044237=IEA, GO:0005851=IDA, GO:0042552=IMP, GO:0006417=NAS, GO:0009749=ISS, GO:0032057=ISS, GO:0014003=IMP, GO:0006446=IBA, GO:0031369=ISS, GO:0044267=TAS, GO:0046523=IBA} L-methionine salvage from methylthioadenosine, cellular metabolic process, cellular protein metabolic process, cellular response to stimulus, gene expression, myelination, negative regulation of translational initiation, negative regulation of translational initiation in response to stress, oligodendrocyte development, ovarian follicle development, regulation of translation, regulation of translational initiation, response to glucose stimulus, response to heat, response to peptide hormone stimulus, translation, translational initiation cytoplasm, cytosol, eukaryotic translation initiation factor 2B complex S-methyl-5-thioribose-1-phosphate isomerase activity, guanyl-nucleotide exchange factor activity, protein binding, translation initiation factor activity, translation initiation factor binding Human EIF2B5 Reactome UniProtKB {GO:0005515=PMID:15060152, GO:0010467=Reactome:REACT_71, GO:0051716=PMID:8626696, GO:0009408=GO_REF:0000024, GO:0048708=PMID:15723074, GO:0003743=PMID:16289705, GO:0043434=GO_REF:0000024, GO:0005634=GO_REF:0000024, GO:0006412=Reactome:REACT_1014, GO:0006413=Reactome:REACT_2159, GO:0005829=Reactome:REACT_1401, GO:0005085=GO_REF:0000024, GO:0001541=PMID:15507143, GO:0005737=PMID:11323413, GO:0045948=GO_REF:0000024, GO:0005851=PMID:11323413, GO:0016070=GO_REF:0000002, GO:0042552=PMID:15723074, GO:0006950=PMID:16041584, GO:0009749=GO_REF:0000024, GO:0032057=GO_REF:0000024, GO:0014002=PMID:15723074, GO:0014003=PMID:15217090, GO:0031369=GO_REF:0000024, GO:0044267=Reactome:REACT_17015, GO:0016740=GO_REF:0000002} Q13144 Translation initiation factor eIF-2B subunit epsilon protein 20130213 {GO:0005515=IPI, GO:0010467=TAS, GO:0051716=IDA, GO:0009408=ISS, GO:0048708=IMP, GO:0003743=IDA, GO:0043434=ISS, GO:0005634=ISS, GO:0006412=TAS, GO:0006413=TAS, GO:0005829=TAS, GO:0005085=ISS, GO:0001541=IMP, GO:0005737=IDA, GO:0045948=ISS, GO:0005851=IDA, GO:0016070=IEA, GO:0042552=IMP, GO:0006950=IMP, GO:0009749=ISS, GO:0032057=ISS, GO:0014002=IMP, GO:0014003=IMP, GO:0031369=ISS, GO:0044267=TAS, GO:0016740=IEA} RNA metabolic process, astrocyte development, astrocyte differentiation, cellular protein metabolic process, cellular response to stimulus, gene expression, myelination, negative regulation of translational initiation in response to stress, oligodendrocyte development, ovarian follicle development, positive regulation of translational initiation, response to glucose stimulus, response to heat, response to peptide hormone stimulus, response to stress, translation, translational initiation cytoplasm, cytosol, eukaryotic translation initiation factor 2B complex, nucleus guanyl-nucleotide exchange factor activity, protein binding, transferase activity, translation initiation factor activity, translation initiation factor binding Human EIF2D InterPro UniProtKB {GO:0005737=PMID:20566627, GO:0003723=GO_REF:0000002, GO:0003743=PMID:20566627, GO:0004872=PMID:2482295, GO:0006886=PMID:2482295} Q5SY38 Eukaryotic translation initiation factor 2D protein 20130413 {GO:0005737=IDA, GO:0003723=IEA, GO:0003743=IDA, GO:0004872=TAS, GO:0006886=TAS} intracellular protein transport cytoplasm RNA binding, receptor activity, translation initiation factor activity Human InterPro:IPR002478 EIF2S1 IntAct UniProtKB {GO:0005851=PMID:11323413, GO:0005515=PMID:22323517, GO:0010467=Reactome:REACT_71, GO:0005850=GO_REF:0000002, GO:0010494=GO_REF:0000024, GO:0003743=PMID:16289705, GO:0005634=GO_REF:0000019, GO:0006412=Reactome:REACT_1014, GO:0006413=Reactome:REACT_2159, GO:0030968=Reactome:REACT_18356, GO:0005829=Reactome:REACT_18275, GO:0043558=GO_REF:0000019, GO:0046777=GO_REF:0000019, GO:0043022=PMID:17894550, GO:0006987=Reactome:REACT_18277, GO:0044267=Reactome:REACT_17015, GO:0005844=PMID:2948954} P05198 Eukaryotic translation initiation factor 2 subunit 1 protein 20130415 {GO:0005851=IDA, GO:0005515=IPI, GO:0010467=TAS, GO:0005850=IEA, GO:0010494=ISS, GO:0003743=IDA, GO:0005634=IEA, GO:0006412=TAS, GO:0006413=TAS, GO:0030968=TAS, GO:0005829=TAS, GO:0043558=IEA, GO:0046777=IEA, GO:0043022=IDA, GO:0006987=TAS, GO:0044267=TAS, GO:0005844=TAS} activation of signaling protein activity involved in unfolded protein response, cellular protein metabolic process, endoplasmic reticulum unfolded protein response, gene expression, protein autophosphorylation, regulation of translational initiation in response to stress, translation, translational initiation cytoplasmic stress granule, cytosol, eukaryotic translation initiation factor 2 complex, eukaryotic translation initiation factor 2B complex, nucleus, polysome protein binding, ribosome binding, translation initiation factor activity Human UniProtKB:O00571 EIF2S2 IntAct UniProtKB {GO:0005515=PMID:16288713, GO:0010467=Reactome:REACT_71, GO:0005850=PMID:3044606, GO:0003723=PMID:3044606, GO:0003743=PMID:16289705, GO:0044267=Reactome:REACT_17015, GO:0006412=Reactome:REACT_1014, GO:0006413=Reactome:REACT_2159, GO:0008135=PMID:3044606, GO:0046872=GO_REF:0000037, GO:0005829=Reactome:REACT_1904} P20042 Eukaryotic translation initiation factor 2 subunit 2 protein 20130415 {GO:0005515=IPI, GO:0010467=TAS, GO:0005850=TAS, GO:0003723=TAS, GO:0003743=IDA, GO:0044267=TAS, GO:0006412=TAS, GO:0006413=TAS, GO:0008135=TAS, GO:0046872=IEA, GO:0005829=TAS} cellular protein metabolic process, gene expression, translation, translational initiation cytosol, eukaryotic translation initiation factor 2 complex RNA binding, metal ion binding, protein binding, translation factor activity, nucleic acid binding, translation initiation factor activity Human UniProtKB:P41091 EIF2S3 GOC UniProtKB {GO:0006184=PMID:8106381, GO:0005515=PMID:16288713, GO:0010467=Reactome:REACT_71, GO:0003924=GO_REF:0000002, GO:0003743=PMID:10900014, GO:0005525=GO_REF:0000037, GO:0044267=Reactome:REACT_17015, GO:0006412=Reactome:REACT_1014, GO:0008135=PMID:10900014, GO:0006413=Reactome:REACT_2159, GO:0005829=Reactome:REACT_1904} P41091 Eukaryotic translation initiation factor 2 subunit 3 protein 20130413 {GO:0006184=TAS, GO:0005515=IPI, GO:0010467=TAS, GO:0003924=IEA, GO:0003743=IDA, GO:0005525=IEA, GO:0044267=TAS, GO:0006412=TAS, GO:0008135=IDA, GO:0006413=TAS, GO:0005829=TAS} GTP catabolic process, cellular protein metabolic process, gene expression, translation, translational initiation cytosol GTP binding, GTPase activity, protein binding, translation factor activity, nucleic acid binding, translation initiation factor activity Human EIF3A HPA UniProtKB {GO:0005515=PMID:22190034, GO:0010467=Reactome:REACT_71, GO:0005852=PMID:17322308, GO:0001732=PMID:17581632, GO:0005730=GO_REF:0000052, GO:0003743=PMID:17581632, GO:0005634=GO_REF:0000052, GO:0006412=Reactome:REACT_1014, GO:0006413=Reactome:REACT_2159, GO:0005829=Reactome:REACT_1904, GO:0005737=GO_REF:0000052, GO:0005198=PMID:9150439, GO:0044267=Reactome:REACT_17015} Q14152 Eukaryotic translation initiation factor 3 subunit A protein 20110516 {GO:0005515=IPI, GO:0010467=TAS, GO:0005852=IDA, GO:0001732=IDA, GO:0005730=IDA, GO:0003743=IDA, GO:0005634=IDA, GO:0006412=TAS, GO:0006413=TAS, GO:0005829=TAS, GO:0005737=IDA, GO:0005198=NAS, GO:0044267=TAS} cellular protein metabolic process, formation of translation initiation complex, gene expression, translation, translational initiation cytoplasm, cytosol, eukaryotic translation initiation factor 3 complex, nucleolus, nucleus protein binding, structural molecule activity, translation initiation factor activity Human EIF3B Reactome UniProtKB {GO:0005515=PMID:18599441, GO:0010467=Reactome:REACT_71, GO:0032947=PMID:17322308, GO:0005852=PMID:17581632, GO:0000166=GO_REF:0000002, GO:0006446=PMID:8995410, GO:0003743=PMID:18599441, GO:0031369=GO_REF:0000002, GO:0044267=Reactome:REACT_17015, GO:0006412=Reactome:REACT_1014, GO:0006413=Reactome:REACT_2159, GO:0005829=Reactome:REACT_1904} P55884 Eukaryotic translation initiation factor 3 subunit B protein 20130213 {GO:0005515=IPI, GO:0010467=TAS, GO:0032947=TAS, GO:0005852=IDA, GO:0000166=IEA, GO:0006446=IDA, GO:0003743=IC, GO:0031369=IEA, GO:0044267=TAS, GO:0006412=TAS, GO:0006413=TAS, GO:0005829=TAS} cellular protein metabolic process, gene expression, regulation of translational initiation, translation, translational initiation cytosol, eukaryotic translation initiation factor 3 complex nucleotide binding, protein binding, protein complex scaffold, translation initiation factor activity, translation initiation factor binding Human EIF3C IntAct UniProtKB {GO:0005515=PMID:22190034, GO:0010467=Reactome:REACT_71, GO:0005852=PMID:17322308, GO:0003743=PMID:17322308, GO:0031369=GO_REF:0000002, GO:0044267=Reactome:REACT_17015, GO:0006412=Reactome:REACT_1014, GO:0006413=Reactome:REACT_2159, GO:0005829=Reactome:REACT_1904} Q99613 Eukaryotic translation initiation factor 3 subunit C protein 20130415 {GO:0005515=IPI, GO:0010467=TAS, GO:0005852=IDA, GO:0003743=IC, GO:0031369=IEA, GO:0044267=TAS, GO:0006412=TAS, GO:0006413=TAS, GO:0005829=TAS} cellular protein metabolic process, gene expression, translation, translational initiation cytosol, eukaryotic translation initiation factor 3 complex protein binding, translation initiation factor activity, translation initiation factor binding Human UniProtKB:Q9Q2G4 EIF3CL UniProtKB UniProtKB {GO:0005852=GO_REF:0000002, GO:0003743=GO_REF:0000038, GO:0031369=GO_REF:0000002} B5ME19 Eukaryotic translation initiation factor 3 subunit C protein 20130413 {GO:0005852=IEA, GO:0003743=IEA, GO:0031369=IEA} eukaryotic translation initiation factor 3 complex translation initiation factor activity, translation initiation factor binding Human UniProtKB-KW:KW-0396 EIF3D IntAct UniProtKB {GO:0005515=PMID:22190034, GO:0010467=Reactome:REACT_71, GO:0005852=PMID:18599441, GO:0001732=GO_REF:0000019, GO:0003743=PMID:18599441, GO:0044267=Reactome:REACT_17015, GO:0006412=Reactome:REACT_1014, GO:0006413=Reactome:REACT_2159, GO:0005829=Reactome:REACT_1904} O15371 Eukaryotic translation initiation factor 3 subunit D protein 20130415 {GO:0005515=IPI, GO:0010467=TAS, GO:0005852=IDA, GO:0001732=IEA, GO:0003743=IC, GO:0044267=TAS, GO:0006412=TAS, GO:0006413=TAS, GO:0005829=TAS} cellular protein metabolic process, formation of translation initiation complex, gene expression, translation, translational initiation cytosol, eukaryotic translation initiation factor 3 complex protein binding, translation initiation factor activity Human UniProtKB:Q9Q2G4 EIF3E HPA UniProtKB {GO:0005515=PMID:22190034, GO:0010467=Reactome:REACT_71, GO:0005852=PMID:10504338, GO:0003743=PMID:17322308, GO:0005634=GO_REF:0000052, GO:0006412=Reactome:REACT_1014, GO:0006413=Reactome:REACT_2159, GO:0005829=Reactome:REACT_1904, GO:0005737=GO_REF:0000052, GO:0047485=PMID:10504338, GO:0000184=PMID:17468741, GO:0016605=PMID:10504338, GO:0006446=PMID:17468741, GO:0045947=PMID:10504338, GO:0005654=PMID:17468741, GO:0044267=Reactome:REACT_17015, GO:0000785=PMID:17468741} P60228 Eukaryotic translation initiation factor 3 subunit E protein 20101115 {GO:0005515=IPI, GO:0010467=TAS, GO:0005852=NAS, GO:0003743=IC, GO:0005634=IDA, GO:0006412=TAS, GO:0006413=TAS, GO:0005829=TAS, GO:0005737=IDA, GO:0047485=IPI, GO:0000184=IMP, GO:0016605=IDA, GO:0006446=NAS, GO:0045947=NAS, GO:0005654=NAS, GO:0044267=TAS, GO:0000785=NAS} cellular protein metabolic process, gene expression, negative regulation of translational initiation, nuclear-transcribed mRNA catabolic process, nonsense-mediated decay, regulation of translational initiation, translation, translational initiation PML body, chromatin, cytoplasm, cytosol, eukaryotic translation initiation factor 3 complex, nucleoplasm, nucleus protein N-terminus binding, protein binding, translation initiation factor activity Human EIF3F IntAct UniProtKB {GO:0005515=PMID:22190034, GO:0010467=Reactome:REACT_71, GO:0005852=PMID:17581632, GO:0006508=GO_REF:0000037, GO:0003743=PMID:17581632, GO:0008234=GO_REF:0000037, GO:0044267=Reactome:REACT_17015, GO:0006412=Reactome:REACT_1014, GO:0006413=Reactome:REACT_2159, GO:0005829=Reactome:REACT_1904} O00303 Eukaryotic translation initiation factor 3 subunit F protein 20130415 {GO:0005515=IPI, GO:0010467=TAS, GO:0005852=IDA, GO:0006508=IEA, GO:0003743=IDA, GO:0008234=IEA, GO:0044267=TAS, GO:0006412=TAS, GO:0006413=TAS, GO:0005829=TAS} cellular protein metabolic process, gene expression, proteolysis, translation, translational initiation cytosol, eukaryotic translation initiation factor 3 complex cysteine-type peptidase activity, protein binding, translation initiation factor activity Human UniProtKB:Q9Q2G4 EIF3G Reactome UniProtKB {GO:0005515=PMID:17094969, GO:0010467=Reactome:REACT_71, GO:0048471=GO_REF:0000039, GO:0005852=PMID:18599441, GO:0000166=GO_REF:0000002, GO:0003743=PMID:18599441, GO:0005634=GO_REF:0000039, GO:0044267=Reactome:REACT_17015, GO:0006412=Reactome:REACT_1014, GO:0006413=Reactome:REACT_2159, GO:0005829=Reactome:REACT_1904} O75821 Eukaryotic translation initiation factor 3 subunit G protein 20130213 {GO:0005515=IPI, GO:0010467=TAS, GO:0048471=IEA, GO:0005852=IDA, GO:0000166=IEA, GO:0003743=IC, GO:0005634=IEA, GO:0044267=TAS, GO:0006412=TAS, GO:0006413=TAS, GO:0005829=TAS} cellular protein metabolic process, gene expression, translation, translational initiation cytosol, eukaryotic translation initiation factor 3 complex, nucleus, perinuclear region of cytoplasm nucleotide binding, protein binding, translation initiation factor activity Human EIF3H HPA UniProtKB {GO:0005515=PMID:22190034, GO:0010467=Reactome:REACT_71, GO:0005737=GO_REF:0000052, GO:0005852=PMID:18599441, GO:0006446=PMID:9341143, GO:0003743=PMID:18599441, GO:0044267=Reactome:REACT_17015, GO:0006412=Reactome:REACT_1014, GO:0006413=Reactome:REACT_2159, GO:0005829=Reactome:REACT_1904} O15372 Eukaryotic translation initiation factor 3 subunit H protein 20100326 {GO:0005515=IPI, GO:0010467=TAS, GO:0005737=IDA, GO:0005852=IDA, GO:0006446=TAS, GO:0003743=IC, GO:0044267=TAS, GO:0006412=TAS, GO:0006413=TAS, GO:0005829=TAS} cellular protein metabolic process, gene expression, regulation of translational initiation, translation, translational initiation cytoplasm, cytosol, eukaryotic translation initiation factor 3 complex protein binding, translation initiation factor activity Human EIF3I ENSEMBL UniProtKB {GO:0010467=Reactome:REACT_71, GO:0005852=GO_REF:0000019, GO:0003743=PMID:17581632, GO:0044267=Reactome:REACT_17015, GO:0006412=Reactome:REACT_1014, GO:0006413=GO_REF:0000019, GO:0005829=Reactome:REACT_1904} Q5TFK1 Eukaryotic translation initiation factor 3 subunit I protein 20130413 {GO:0010467=TAS, GO:0005852=IEA, GO:0003743=IDA, GO:0044267=TAS, GO:0006412=TAS, GO:0006413=IEA, GO:0005829=TAS} cellular protein metabolic process, gene expression, translation, translational initiation cytosol, eukaryotic translation initiation factor 3 complex translation initiation factor activity Human Ensembl:ENSMUSP00000099653 EIF3J Reactome UniProtKB {GO:0010467=Reactome:REACT_71, GO:0005852=PMID:18599441, GO:0003743=PMID:18599441, GO:0044267=Reactome:REACT_17015, GO:0006412=Reactome:REACT_1014, GO:0006413=Reactome:REACT_2159, GO:0005829=Reactome:REACT_1904} O75822 Eukaryotic translation initiation factor 3 subunit J protein 20080912 {GO:0010467=TAS, GO:0005852=IDA, GO:0003743=IC, GO:0044267=TAS, GO:0006412=TAS, GO:0006413=TAS, GO:0005829=TAS} cellular protein metabolic process, gene expression, translation, translational initiation cytosol, eukaryotic translation initiation factor 3 complex translation initiation factor activity Human EIF3K HPA UniProtKB {GO:0005515=PMID:22190034, GO:0010467=Reactome:REACT_71, GO:0005852=PMID:17322308, GO:0006446=GO_REF:0000002, GO:0005730=GO_REF:0000052, GO:0003743=PMID:17322308, GO:0043022=GO_REF:0000002, GO:0005634=GO_REF:0000052, GO:0044267=Reactome:REACT_17015, GO:0006412=Reactome:REACT_1014, GO:0006413=Reactome:REACT_2159, GO:0005829=Reactome:REACT_1904} Q9UBQ5 Eukaryotic translation initiation factor 3 subunit K protein 20111111 {GO:0005515=IPI, GO:0010467=TAS, GO:0005852=IDA, GO:0006446=IEA, GO:0005730=IDA, GO:0003743=IC, GO:0043022=IEA, GO:0005634=IDA, GO:0044267=TAS, GO:0006412=TAS, GO:0006413=TAS, GO:0005829=TAS} cellular protein metabolic process, gene expression, regulation of translational initiation, translation, translational initiation cytosol, eukaryotic translation initiation factor 3 complex, nucleolus, nucleus protein binding, ribosome binding, translation initiation factor activity NOT Human EIF3L IntAct UniProtKB {GO:0005515=PMID:22190034, GO:0005852=PMID:17322308, GO:0001650=GO_REF:0000019, GO:0003743=PMID:17322308, GO:0005654=GO_REF:0000019, GO:0006413=PMID:17322308} Q9Y262 Eukaryotic translation initiation factor 3 subunit L protein 20130415 {GO:0005515=IPI, GO:0005852=IDA, GO:0001650=IEA, GO:0003743=IC, GO:0005654=IEA, GO:0006413=IC} translational initiation eukaryotic translation initiation factor 3 complex, fibrillar center, nucleoplasm protein binding, translation initiation factor activity Human UniProtKB:Q9Q2G4 EIF3M IntAct UniProtKB {GO:0005515=PMID:22190034, GO:0005852=PMID:17322308, GO:0003743=PMID:17322308, GO:0006413=PMID:17322308} Q7L2H7 Eukaryotic translation initiation factor 3 subunit M protein 20130415 {GO:0005515=IPI, GO:0005852=IDA, GO:0003743=IC, GO:0006413=IC} translational initiation eukaryotic translation initiation factor 3 complex protein binding, translation initiation factor activity Human UniProtKB:Q9Q2G4 EIF4A1 IntAct UniProtKB {GO:0008026=GO_REF:0000002, GO:0000339=PMID:3215517, GO:0005515=PMID:19203580, GO:0010467=Reactome:REACT_71, GO:0016281=PMID:9168945, GO:0016070=Reactome:REACT_21257, GO:0016071=Reactome:REACT_20605, GO:0019221=Reactome:REACT_25229, GO:0004386=PMID:3215517, GO:0003743=GO_REF:0000037, GO:0003676=GO_REF:0000002, GO:0003729=PMID:3215517, GO:0006412=Reactome:REACT_1014, GO:0005524=GO_REF:0000037, GO:0006413=Reactome:REACT_2159, GO:0005829=Reactome:REACT_115968, GO:0019048=GO_REF:0000037, GO:0044267=Reactome:REACT_17015, GO:0008135=PMID:3215517, GO:0000289=Reactome:REACT_20514, GO:0000288=Reactome:REACT_20639} P60842 Eukaryotic initiation factor 4A-I protein 20130415 {GO:0008026=IEA, GO:0000339=TAS, GO:0005515=IPI, GO:0010467=TAS, GO:0016281=TAS, GO:0016070=TAS, GO:0016071=TAS, GO:0019221=TAS, GO:0004386=TAS, GO:0003743=IEA, GO:0003676=IEA, GO:0003729=TAS, GO:0006412=TAS, GO:0005524=IEA, GO:0006413=TAS, GO:0005829=TAS, GO:0019048=IEA, GO:0044267=TAS, GO:0008135=TAS, GO:0000289=TAS, GO:0000288=TAS} RNA metabolic process, cellular protein metabolic process, cytokine-mediated signaling pathway, gene expression, mRNA metabolic process, nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay, nuclear-transcribed mRNA poly(A) tail shortening, translation, translational initiation, virus-host interaction cytosol, eukaryotic translation initiation factor 4F complex ATP binding, ATP-dependent helicase activity, RNA cap binding, helicase activity, mRNA binding, nucleic acid binding, protein binding, translation factor activity, nucleic acid binding, translation initiation factor activity Human UniProtKB:Q15056 EIF4A2 UniProtKB UniProtKB {GO:0005515=PMID:11408474, GO:0008026=GO_REF:0000002, GO:0010467=Reactome:REACT_71, GO:0016281=PMID:8521730, GO:0016070=Reactome:REACT_21257, GO:0016071=Reactome:REACT_20605, GO:0019221=Reactome:REACT_25229, GO:0004386=PMID:8521730, GO:0003743=GO_REF:0000038, GO:0003676=GO_REF:0000002, GO:0005524=GO_REF:0000038, GO:0006412=Reactome:REACT_1014, GO:0006413=Reactome:REACT_2159, GO:0005829=Reactome:REACT_115968, GO:0019048=GO_REF:0000037, GO:0006446=PMID:8521730, GO:0044267=Reactome:REACT_17015, GO:0000289=Reactome:REACT_20514, GO:0000288=Reactome:REACT_20639} Q9NZE6 BM-010 protein 20130413 {GO:0005515=IPI, GO:0008026=IEA, GO:0010467=TAS, GO:0016281=TAS, GO:0016070=TAS, GO:0016071=TAS, GO:0019221=TAS, GO:0004386=TAS, GO:0003743=IEA, GO:0003676=IEA, GO:0005524=IEA, GO:0006412=TAS, GO:0006413=TAS, GO:0005829=TAS, GO:0019048=IEA, GO:0006446=TAS, GO:0044267=TAS, GO:0000289=TAS, GO:0000288=TAS} RNA metabolic process, cellular protein metabolic process, cytokine-mediated signaling pathway, gene expression, mRNA metabolic process, nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay, nuclear-transcribed mRNA poly(A) tail shortening, regulation of translational initiation, translation, translational initiation, virus-host interaction cytosol, eukaryotic translation initiation factor 4F complex ATP binding, ATP-dependent helicase activity, helicase activity, nucleic acid binding, protein binding, translation initiation factor activity Human UniProtKB-KW:KW-0067 EIF4A3 IntAct UniProtKB {GO:0048026=GO_REF:0000019, GO:0005515=PMID:23084401, GO:0017148=PMID:10523622, GO:0010467=Reactome:REACT_71, GO:0006364=GO_REF:0000037, GO:0019221=Reactome:REACT_25229, GO:0005634=GO_REF:0000019, GO:0071013=PMID:11991638, GO:0005829=Reactome:REACT_115968, GO:0004004=PMID:10523622, GO:0005737=PMID:10523622, GO:0000184=Reactome:REACT_75886, GO:0045944=GO_REF:0000019, GO:0008143=PMID:10523622, GO:0035145=PMID:16601204, GO:0000289=Reactome:REACT_20514, GO:0000288=Reactome:REACT_20639, GO:0008026=GO_REF:0000002, GO:0016070=Reactome:REACT_21257, GO:0016071=Reactome:REACT_20605, GO:0045727=PMID:18423201, GO:0003676=GO_REF:0000002, GO:0005524=PMID:10523622, GO:0016607=GO_REF:0000039, GO:0000398=PMID:11991638, GO:0051028=GO_REF:0000037} P38919 Eukaryotic initiation factor 4A-III protein 20130415 {GO:0048026=IEA, GO:0005515=IPI, GO:0017148=IDA, GO:0010467=TAS, GO:0006364=IEA, GO:0019221=TAS, GO:0005634=IEA, GO:0071013=IDA, GO:0005829=TAS, GO:0004004=IDA, GO:0005737=IDA, GO:0000184=TAS, GO:0045944=IEA, GO:0008143=IDA, GO:0035145=IDA, GO:0000289=TAS, GO:0000288=TAS, GO:0008026=IEA, GO:0016070=TAS, GO:0016071=TAS, GO:0045727=IMP, GO:0003676=IEA, GO:0005524=IDA, GO:0016607=IEA, GO:0000398=IC, GO:0051028=IEA} RNA metabolic process, cytokine-mediated signaling pathway, gene expression, mRNA metabolic process, mRNA splicing, via spliceosome, mRNA transport, negative regulation of translation, nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay, nuclear-transcribed mRNA catabolic process, nonsense-mediated decay, nuclear-transcribed mRNA poly(A) tail shortening, positive regulation of mRNA splicing, via spliceosome, positive regulation of transcription from RNA polymerase II promoter, positive regulation of translation, rRNA processing catalytic step 2 spliceosome, cytoplasm, cytosol, exon-exon junction complex, nuclear speck, nucleus ATP binding, ATP-dependent RNA helicase activity, ATP-dependent helicase activity, nucleic acid binding, poly(A) RNA binding, protein binding Human UniProtKB:Q9Y2W1 EIF4B Reactome UniProtKB {GO:0008286=Reactome:REACT_498, GO:0010467=Reactome:REACT_71, GO:0016281=PMID:2390971, GO:0016070=Reactome:REACT_21257, GO:0016071=Reactome:REACT_20605, GO:0003723=PMID:2390971, GO:0003743=GO_REF:0000037, GO:0003676=GO_REF:0000002, GO:0006412=Reactome:REACT_1014, GO:0006413=Reactome:REACT_2159, GO:0005829=Reactome:REACT_20662, GO:0000166=GO_REF:0000002, GO:0006446=PMID:2390971, GO:0044267=Reactome:REACT_17015, GO:0000289=Reactome:REACT_20514, GO:0000288=Reactome:REACT_20639} P23588 Eukaryotic translation initiation factor 4B protein 20080912 {GO:0008286=TAS, GO:0010467=TAS, GO:0016281=TAS, GO:0016070=TAS, GO:0016071=TAS, GO:0003723=TAS, GO:0003743=IEA, GO:0003676=IEA, GO:0006412=TAS, GO:0006413=TAS, GO:0005829=TAS, GO:0000166=IEA, GO:0006446=TAS, GO:0044267=TAS, GO:0000289=TAS, GO:0000288=TAS} RNA metabolic process, cellular protein metabolic process, gene expression, insulin receptor signaling pathway, mRNA metabolic process, nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay, nuclear-transcribed mRNA poly(A) tail shortening, regulation of translational initiation, translation, translational initiation cytosol, eukaryotic translation initiation factor 4F complex RNA binding, nucleic acid binding, nucleotide binding, translation initiation factor activity Human EIF4E IntAct UniProtKB {GO:0000339=PMID:3469651, GO:0005515=PMID:19060904, GO:0008286=Reactome:REACT_498, GO:0010467=Reactome:REACT_71, GO:0016281=GO_REF:0000019, GO:0010494=PMID:21883093, GO:0030324=GO_REF:0000019, GO:0019221=Reactome:REACT_25229, GO:0003743=GO_REF:0000024, GO:0006412=Reactome:REACT_1014, GO:0006413=Reactome:REACT_2159, GO:0016442=PMID:20616046, GO:0005829=Reactome:REACT_115968, GO:0005737=GO_REF:0000002, GO:0000082=PMID:14673156, GO:0006406=Reactome:REACT_1597, GO:0000932=PMID:20616046, GO:0000289=Reactome:REACT_20514, GO:0000288=Reactome:REACT_20639, GO:0031370=GO_REF:0000019, GO:0016070=Reactome:REACT_21257, GO:0016071=Reactome:REACT_20605, GO:0006417=GO_REF:0000037, GO:0045931=PMID:14673156, GO:0019048=GO_REF:0000037, GO:0044267=Reactome:REACT_17015, GO:0005845=PMID:16271312} P06730 Eukaryotic translation initiation factor 4E protein 20130415 {GO:0000339=TAS, GO:0005515=IPI, GO:0008286=TAS, GO:0010467=TAS, GO:0016281=IEA, GO:0010494=IDA, GO:0030324=IEA, GO:0019221=TAS, GO:0003743=ISS, GO:0006412=TAS, GO:0006413=TAS, GO:0016442=IDA, GO:0005829=TAS, GO:0005737=IEA, GO:0000082=IMP, GO:0006406=TAS, GO:0000932=IDA, GO:0000289=TAS, GO:0000288=TAS, GO:0031370=IEA, GO:0016070=TAS, GO:0016071=TAS, GO:0006417=IEA, GO:0045931=IMP, GO:0019048=IEA, GO:0044267=TAS, GO:0005845=IDA} G1/S transition of mitotic cell cycle, RNA metabolic process, cellular protein metabolic process, cytokine-mediated signaling pathway, gene expression, insulin receptor signaling pathway, lung development, mRNA export from nucleus, mRNA metabolic process, nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay, nuclear-transcribed mRNA poly(A) tail shortening, positive regulation of mitotic cell cycle, regulation of translation, translation, translational initiation, virus-host interaction RNA-induced silencing complex, cytoplasm, cytoplasmic mRNA processing body, cytoplasmic stress granule, cytosol, eukaryotic translation initiation factor 4F complex, mRNA cap binding complex RNA cap binding, eukaryotic initiation factor 4G binding, protein binding, translation initiation factor activity Human UniProtKB:Q9NRA8 EIF4E2 IntAct UniProtKB {GO:0017148=PMID:22751931, GO:0000339=PMID:9582349, GO:0005515=PMID:19060904, GO:0005737=GO_REF:0000002, GO:0019221=Reactome:REACT_25229, GO:0003743=GO_REF:0000037, GO:0008135=PMID:9582349, GO:0031625=PMID:14623119, GO:0005845=PMID:17368478, GO:0005829=Reactome:REACT_115968} O60573 Eukaryotic translation initiation factor 4E type 2 protein 20130415 {GO:0017148=IMP, GO:0000339=TAS, GO:0005515=IPI, GO:0005737=IEA, GO:0019221=TAS, GO:0003743=IEA, GO:0008135=TAS, GO:0031625=IPI, GO:0005845=IDA, GO:0005829=TAS} cytokine-mediated signaling pathway, negative regulation of translation cytoplasm, cytosol, mRNA cap binding complex RNA cap binding, protein binding, translation factor activity, nucleic acid binding, translation initiation factor activity, ubiquitin protein ligase binding Human UniProtKB:Q9NRA8 EIF4E3 Reactome UniProtKB {GO:0005737=GO_REF:0000002, GO:0019221=Reactome:REACT_25229, GO:0003743=GO_REF:0000037, GO:0005845=GO_REF:0000024, GO:0006417=GO_REF:0000037, GO:0005829=Reactome:REACT_115968} Q8N5X7 Eukaryotic translation initiation factor 4E type 3 protein 20130301 {GO:0005737=IEA, GO:0019221=TAS, GO:0003743=IEA, GO:0005845=ISS, GO:0006417=IEA, GO:0005829=TAS} cytokine-mediated signaling pathway, regulation of translation cytoplasm, cytosol, mRNA cap binding complex translation initiation factor activity Human EIF4EBP1 HPA UniProtKB {GO:0008286=Reactome:REACT_498, GO:0005515=PMID:16189514, GO:0031929=PMID:12150926, GO:0010467=Reactome:REACT_71, GO:0030324=GO_REF:0000019, GO:0045471=GO_REF:0000019, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0006412=Reactome:REACT_1014, GO:0006413=Reactome:REACT_2159, GO:0005829=Reactome:REACT_6873, GO:0043234=GO_REF:0000019, GO:0005737=GO_REF:0000052, GO:0045931=PMID:14673156, GO:0000082=PMID:14673156, GO:0031333=GO_REF:0000019, GO:0008190=GO_REF:0000019, GO:0045947=GO_REF:0000019, GO:0044267=Reactome:REACT_17015} Q13541 Eukaryotic translation initiation factor 4E-binding protein 1 protein 20101115 {GO:0008286=TAS, GO:0005515=IPI, GO:0031929=IDA, GO:0010467=TAS, GO:0030324=IEA, GO:0045471=IEA, GO:0005730=IDA, GO:0005634=IDA, GO:0006412=TAS, GO:0006413=TAS, GO:0005829=TAS, GO:0043234=IEA, GO:0005737=IDA, GO:0045931=IMP, GO:0000082=IMP, GO:0031333=IEA, GO:0008190=IEA, GO:0045947=IEA, GO:0044267=TAS} G1/S transition of mitotic cell cycle, TOR signaling cascade, cellular protein metabolic process, gene expression, insulin receptor signaling pathway, lung development, negative regulation of protein complex assembly, negative regulation of translational initiation, positive regulation of mitotic cell cycle, response to ethanol, translation, translational initiation cytoplasm, cytosol, nucleolus, nucleus, protein complex eukaryotic initiation factor 4E binding, protein binding Human EIF4EBP2 PINC UniProtKB {GO:0005515=PMID:16271312, GO:0008286=GO_REF:0000019, GO:0019933=GO_REF:0000019, GO:0008190=GO_REF:0000002, GO:0045947=GO_REF:0000002, GO:0006412=PMID:7935836} Q13542 Eukaryotic translation initiation factor 4E-binding protein 2 protein 20030904 {GO:0005515=IPI, GO:0008286=IEA, GO:0019933=IEA, GO:0008190=IEA, GO:0045947=IEA, GO:0006412=TAS} cAMP-mediated signaling, insulin receptor signaling pathway, negative regulation of translational initiation, translation eukaryotic initiation factor 4E binding, protein binding Human EIF4EBP3 IntAct UniProtKB {GO:0005515=PMID:15153109, GO:0016281=PMID:9593750, GO:0008190=GO_REF:0000002, GO:0045947=PMID:9593750, GO:0030371=PMID:9593750} O60516 Eukaryotic translation initiation factor 4E-binding protein 3 protein 20130415 {GO:0005515=IPI, GO:0016281=NAS, GO:0008190=IEA, GO:0045947=NAS, GO:0030371=NAS} negative regulation of translational initiation eukaryotic translation initiation factor 4F complex eukaryotic initiation factor 4E binding, protein binding, translation repressor activity Human UniProtKB:Q80ZJ3 EIF4ENIF1 HPA UniProtKB {GO:0005515=PMID:19060904, GO:0005737=PMID:10856257, GO:0016607=GO_REF:0000039, GO:0016605=GO_REF:0000039, GO:0008565=PMID:10856257, GO:0003743=GO_REF:0000038, GO:0005634=PMID:10856257, GO:0005829=GO_REF:0000019, GO:0043231=GO_REF:0000052} Q9NRA8 Eukaryotic translation initiation factor 4E transporter protein 20101115 {GO:0005515=IPI, GO:0005737=TAS, GO:0016607=IEA, GO:0016605=IEA, GO:0008565=TAS, GO:0003743=IEA, GO:0005634=TAS, GO:0005829=IEA, GO:0043231=IDA} PML body, cytoplasm, cytosol, intracellular membrane-bounded organelle, nuclear speck, nucleus protein binding, protein transporter activity, translation initiation factor activity Human EIF4G1 IntAct UniProtKB {GO:0008286=Reactome:REACT_498, GO:0005515=PMID:19716330, GO:0010467=Reactome:REACT_71, GO:0008219=GO_REF:0000037, GO:0016281=PMID:9857202, GO:0016070=Reactome:REACT_21257, GO:0016071=Reactome:REACT_20605, GO:0003723=GO_REF:0000002, GO:0019221=Reactome:REACT_25229, GO:0003743=PMID:9372926, GO:0006412=Reactome:REACT_1014, GO:0003677=GO_REF:0000002, GO:0006413=Reactome:REACT_2159, GO:0005829=Reactome:REACT_115968, GO:0005737=GO_REF:0000029, GO:0000184=Reactome:REACT_75886, GO:0019048=GO_REF:0000037, GO:0006446=PMID:9372926, GO:0044267=Reactome:REACT_17015, GO:0000289=Reactome:REACT_20514, GO:0008135=PMID:9857202, GO:0000288=Reactome:REACT_20639} Q04637 Eukaryotic translation initiation factor 4 gamma 1 protein 20130415 {GO:0008286=TAS, GO:0005515=IPI, GO:0010467=TAS, GO:0008219=IEA, GO:0016281=TAS, GO:0016070=TAS, GO:0016071=TAS, GO:0003723=IEA, GO:0019221=TAS, GO:0003743=TAS, GO:0006412=TAS, GO:0003677=IEA, GO:0006413=TAS, GO:0005829=TAS, GO:0005737=NAS, GO:0000184=TAS, GO:0019048=IEA, GO:0006446=NAS, GO:0044267=TAS, GO:0000289=TAS, GO:0008135=TAS, GO:0000288=TAS} RNA metabolic process, cell death, cellular protein metabolic process, cytokine-mediated signaling pathway, gene expression, insulin receptor signaling pathway, mRNA metabolic process, nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay, nuclear-transcribed mRNA catabolic process, nonsense-mediated decay, nuclear-transcribed mRNA poly(A) tail shortening, regulation of translational initiation, translation, translational initiation, virus-host interaction cytoplasm, cytosol, eukaryotic translation initiation factor 4F complex DNA binding, RNA binding, protein binding, translation factor activity, nucleic acid binding, translation initiation factor activity Human UniProtKB:P11940 EIF4G2 IntAct UniProtKB {GO:0005515=PMID:16166382, GO:0008219=PMID:9032289, GO:0016281=PMID:11943866, GO:0016070=GO_REF:0000002, GO:0003723=GO_REF:0000002, GO:0019221=Reactome:REACT_25229, GO:0003743=PMID:11943866, GO:0003677=GO_REF:0000002, GO:0005829=Reactome:REACT_115968, GO:0005737=GO_REF:0000019, GO:0006446=PMID:11943866, GO:0007050=PMID:9032289, GO:0008135=PMID:16289705} P78344 Eukaryotic translation initiation factor 4 gamma 2 protein 20130415 {GO:0005515=IPI, GO:0008219=TAS, GO:0016281=IDA, GO:0016070=IEA, GO:0003723=IEA, GO:0019221=TAS, GO:0003743=IDA, GO:0003677=IEA, GO:0005829=TAS, GO:0005737=IEA, GO:0006446=IDA, GO:0007050=TAS, GO:0008135=IDA} RNA metabolic process, cell cycle arrest, cell death, cytokine-mediated signaling pathway, regulation of translational initiation cytoplasm, cytosol, eukaryotic translation initiation factor 4F complex DNA binding, RNA binding, protein binding, translation factor activity, nucleic acid binding, translation initiation factor activity Human UniProtKB:P60842 EIF4G3 InterPro UniProtKB {GO:0000339=PMID:9418880, GO:0016281=PMID:9418880, GO:0016070=GO_REF:0000002, GO:0003723=GO_REF:0000002, GO:0019221=Reactome:REACT_25229, GO:0003743=GO_REF:0000037, GO:0045727=GO_REF:0000019, GO:0007283=GO_REF:0000019, GO:0003677=GO_REF:0000002, GO:0005829=Reactome:REACT_115968, GO:0007128=GO_REF:0000019, GO:0019048=GO_REF:0000037, GO:0006446=PMID:9418880, GO:0001934=GO_REF:0000019, GO:0008135=PMID:9418880} Q5SWD0 Eukaryotic translation initiation factor 4 gamma 3 protein 20130413 {GO:0000339=TAS, GO:0016281=TAS, GO:0016070=IEA, GO:0003723=IEA, GO:0019221=TAS, GO:0003743=IEA, GO:0045727=IEA, GO:0007283=IEA, GO:0003677=IEA, GO:0005829=TAS, GO:0007128=IEA, GO:0019048=IEA, GO:0006446=TAS, GO:0001934=IEA, GO:0008135=TAS} RNA metabolic process, cytokine-mediated signaling pathway, meiotic prophase I, positive regulation of protein phosphorylation, positive regulation of translation, regulation of translational initiation, spermatogenesis, virus-host interaction cytosol, eukaryotic translation initiation factor 4F complex DNA binding, RNA binding, RNA cap binding, translation factor activity, nucleic acid binding, translation initiation factor activity Human InterPro:IPR016021 EIF4H IntAct UniProtKB {GO:0005515=PMID:19203580, GO:0010467=Reactome:REACT_71, GO:0048471=GO_REF:0000039, GO:0016281=PMID:9516461, GO:0003723=PMID:8812460, GO:0003743=GO_REF:0000037, GO:0006412=Reactome:REACT_1014, GO:0006413=Reactome:REACT_2159, GO:0005829=Reactome:REACT_1904, GO:0019953=GO_REF:0000019, GO:0048589=GO_REF:0000019, GO:0000166=GO_REF:0000002, GO:0019048=GO_REF:0000037, GO:0006446=PMID:9516461, GO:0044267=Reactome:REACT_17015, GO:0008135=PMID:9516461} Q15056 Eukaryotic translation initiation factor 4H protein 20130415 {GO:0005515=IPI, GO:0010467=TAS, GO:0048471=IEA, GO:0016281=TAS, GO:0003723=TAS, GO:0003743=IEA, GO:0006412=TAS, GO:0006413=TAS, GO:0005829=TAS, GO:0019953=IEA, GO:0048589=IEA, GO:0000166=IEA, GO:0019048=IEA, GO:0006446=TAS, GO:0044267=TAS, GO:0008135=TAS} cellular protein metabolic process, developmental growth, gene expression, regulation of translational initiation, sexual reproduction, translation, translational initiation, virus-host interaction cytosol, eukaryotic translation initiation factor 4F complex, perinuclear region of cytoplasm RNA binding, nucleotide binding, protein binding, translation factor activity, nucleic acid binding, translation initiation factor activity Human UniProtKB:P60842 EIF5 GOC UniProtKB {GO:0010467=Reactome:REACT_71, GO:0016070=GO_REF:0000002, GO:0003924=PMID:8663286, GO:0003743=PMID:8663286, GO:0005525=GO_REF:0000037, GO:0006412=Reactome:REACT_1014, GO:0006413=Reactome:REACT_2159, GO:0005829=Reactome:REACT_1060, GO:0006184=PMID:8663286, GO:0005737=GO_REF:0000052, GO:0006446=PMID:8663286, GO:0044267=Reactome:REACT_17015, GO:0008135=PMID:8663286} P55010 Eukaryotic translation initiation factor 5 protein 20130413 {GO:0010467=TAS, GO:0016070=IEA, GO:0003924=TAS, GO:0003743=NAS, GO:0005525=IEA, GO:0006412=TAS, GO:0006413=TAS, GO:0005829=TAS, GO:0006184=TAS, GO:0005737=IDA, GO:0006446=TAS, GO:0044267=TAS, GO:0008135=TAS} GTP catabolic process, RNA metabolic process, cellular protein metabolic process, gene expression, regulation of translational initiation, translation, translational initiation cytoplasm, cytosol GTP binding, GTPase activity, translation factor activity, nucleic acid binding, translation initiation factor activity Human EIF5A Reactome UniProtKB {GO:0005515=PMID:17213197, GO:0008284=PMID:14622290, GO:0008612=Reactome:REACT_12469, GO:0003723=PMID:15303967, GO:0005634=PMID:17187778, GO:0006917=PMID:15371445, GO:0003746=GO_REF:0000024, GO:0005829=Reactome:REACT_12551, GO:0006913=PMID:10381392, GO:0006452=GO_REF:0000002, GO:0045905=GO_REF:0000002, GO:0005737=PMID:12210765, GO:0047485=PMID:15371445, GO:0006406=PMID:9465063, GO:0005643=PMID:10381392, GO:0005642=PMID:12210765, GO:0006611=PMID:8596953, GO:0005789=GO_REF:0000039, GO:0043022=GO_REF:0000002, GO:0017070=PMID:9285100, GO:0044267=Reactome:REACT_17015, GO:0045901=GO_REF:0000024, GO:0043687=Reactome:REACT_22161} P63241 Eukaryotic translation initiation factor 5A-1 protein 20130301 {GO:0005515=IPI, GO:0008284=IGI, GO:0008612=TAS, GO:0003723=IDA, GO:0005634=IDA, GO:0006917=IDA, GO:0003746=ISS, GO:0005829=TAS, GO:0006913=IMP, GO:0006452=IEA, GO:0045905=IEA, GO:0005737=IDA, GO:0047485=IPI, GO:0006406=IMP, GO:0005643=IDA, GO:0005642=IDA, GO:0006611=IMP, GO:0005789=IEA, GO:0043022=IEA, GO:0017070=IDA, GO:0044267=TAS, GO:0045901=ISS, GO:0043687=TAS} cellular protein metabolic process, induction of apoptosis, mRNA export from nucleus, nucleocytoplasmic transport, peptidyl-lysine modification to hypusine, positive regulation of cell proliferation, positive regulation of translational elongation, positive regulation of translational termination, post-translational protein modification, protein export from nucleus, translational frameshifting annulate lamellae, cytoplasm, cytosol, endoplasmic reticulum membrane, nuclear pore, nucleus RNA binding, U6 snRNA binding, protein N-terminus binding, protein binding, ribosome binding, translation elongation factor activity Human EIF5A2 Reactome UniProtKB {GO:0005515=PMID:14622290, GO:0008284=PMID:14622290, GO:0008612=Reactome:REACT_12469, GO:0007283=PMID:11161802, GO:0003746=GO_REF:0000037, GO:0015031=GO_REF:0000037, GO:0005829=Reactome:REACT_12551, GO:0006452=GO_REF:0000002, GO:0045905=GO_REF:0000002, GO:0005643=GO_REF:0000039, GO:0005789=GO_REF:0000039, GO:0043022=GO_REF:0000002, GO:0051028=GO_REF:0000037, GO:0044267=Reactome:REACT_17015, GO:0045901=GO_REF:0000002, GO:0010509=PMID:11161802, GO:0043687=Reactome:REACT_22161} Q9GZV4 Eukaryotic translation initiation factor 5A-2 protein 20130301 {GO:0005515=IPI, GO:0008284=IGI, GO:0008612=TAS, GO:0007283=NAS, GO:0003746=IEA, GO:0015031=IEA, GO:0005829=TAS, GO:0006452=IEA, GO:0045905=IEA, GO:0005643=IEA, GO:0005789=IEA, GO:0043022=IEA, GO:0051028=IEA, GO:0044267=TAS, GO:0045901=IEA, GO:0010509=NAS, GO:0043687=TAS} cellular protein metabolic process, mRNA transport, peptidyl-lysine modification to hypusine, polyamine homeostasis, positive regulation of cell proliferation, positive regulation of translational elongation, positive regulation of translational termination, post-translational protein modification, protein transport, spermatogenesis, translational frameshifting cytosol, endoplasmic reticulum membrane, nuclear pore protein binding, ribosome binding, translation elongation factor activity Human EIF5AL1 UniProtKB UniProtKB {GO:0045905=GO_REF:0000002, GO:0006452=GO_REF:0000002, GO:0008612=GO_REF:0000002, GO:0005643=GO_REF:0000039, GO:0005789=GO_REF:0000039, GO:0043022=GO_REF:0000002, GO:0051028=GO_REF:0000037, GO:0015031=GO_REF:0000037, GO:0003746=GO_REF:0000037, GO:0045901=GO_REF:0000002} Q6IS14 Eukaryotic translation initiation factor 5A-1-like protein 20130413 {GO:0045905=IEA, GO:0006452=IEA, GO:0008612=IEA, GO:0005643=IEA, GO:0005789=IEA, GO:0043022=IEA, GO:0051028=IEA, GO:0015031=IEA, GO:0003746=IEA, GO:0045901=IEA} mRNA transport, peptidyl-lysine modification to hypusine, positive regulation of translational elongation, positive regulation of translational termination, protein transport, translational frameshifting endoplasmic reticulum membrane, nuclear pore ribosome binding, translation elongation factor activity Human UniProtKB-SubCell:SL-0097 EIF5B IntAct UniProtKB {GO:0005515=PMID:20195357, GO:0010467=Reactome:REACT_71, GO:0006446=PMID:10200264, GO:0003924=GO_REF:0000002, GO:0003743=PMID:10200264, GO:0005525=GO_REF:0000037, GO:0044267=Reactome:REACT_17015, GO:0006412=Reactome:REACT_1014, GO:0006413=Reactome:REACT_2159, GO:0005829=Reactome:REACT_198} O60841 Eukaryotic translation initiation factor 5B protein 20130415 {GO:0005515=IPI, GO:0010467=TAS, GO:0006446=NAS, GO:0003924=IEA, GO:0003743=NAS, GO:0005525=IEA, GO:0044267=TAS, GO:0006412=TAS, GO:0006413=TAS, GO:0005829=TAS} cellular protein metabolic process, gene expression, regulation of translational initiation, translation, translational initiation cytosol GTP binding, GTPase activity, protein binding, translation initiation factor activity Human UniProtKB:P14921 EIF6 HPA UniProtKB {GO:0005515=PMID:21903422, GO:0005737=GO_REF:0000039, GO:0042256=PMID:21536732, GO:0005730=GO_REF:0000052, GO:0003743=GO_REF:0000020, GO:0043022=PMID:21536732, GO:0005634=GO_REF:0000052, GO:0043023=GO_REF:0000020, GO:0042273=GO_REF:0000020, GO:0000054=GO_REF:0000020, GO:0005638=GO_REF:0000019} P56537 Eukaryotic translation initiation factor 6 protein 20111111 {GO:0005515=IPI, GO:0005737=IEA, GO:0042256=IMP, GO:0005730=IDA, GO:0003743=IEA, GO:0043022=IDA, GO:0005634=IDA, GO:0043023=IEA, GO:0042273=IEA, GO:0000054=IEA, GO:0005638=IEA} mature ribosome assembly, ribosomal large subunit biogenesis, ribosomal subunit export from nucleus cytoplasm, lamin filament, nucleolus, nucleus protein binding, ribosomal large subunit binding, ribosome binding, translation initiation factor activity NOT Human ELAC2 UniProtKB UniProtKB {GO:0005739=GO_REF:0000019, GO:0004519=GO_REF:0000037, GO:0016787=GO_REF:0000002, GO:0005634=GO_REF:0000039, GO:0046872=GO_REF:0000037, GO:0008033=GO_REF:0000037} Q9BQ52 Zinc phosphodiesterase ELAC protein 2 protein 20130413 {GO:0005739=IEA, GO:0004519=IEA, GO:0016787=IEA, GO:0005634=IEA, GO:0046872=IEA, GO:0008033=IEA} tRNA processing mitochondrion, nucleus endonuclease activity, hydrolase activity, metal ion binding Human UniProtKB-SubCell:SL-0191 ELANE BHF-UCL UniProtKB {GO:0005515=PMID:21979170, GO:0004252=GO_REF:0000002, GO:0002020=PMID:6980881, GO:0030163=PMID:12887060, GO:0050922=PMID:15140022, GO:0022617=Reactome:REACT_118572, GO:0043406=PMID:14730209, GO:0030198=Reactome:REACT_118779, GO:0045079=PMID:12223522, GO:0030574=Reactome:REACT_150401, GO:0006508=PMID:11907569, GO:0030141=PMID:11907569, GO:0009411=PMID:11928814, GO:0008201=PMID:11907569, GO:0009986=PMID:12114510, GO:0045415=PMID:12223522, GO:0045416=PMID:14730209, GO:0006874=PMID:15140022, GO:0005576=Reactome:REACT_150438, GO:0048661=PMID:15010259, GO:0051635=PMID:14705961, GO:0019955=PMID:12393522, GO:0004175=PMID:6980881, GO:0050728=PMID:15140022, GO:0008233=PMID:11907569} P08246 Neutrophil elastase protein 20111202 {GO:0005515=IPI, GO:0004252=IEA, GO:0002020=IPI, GO:0030163=NAS, GO:0050922=NAS, GO:0022617=TAS, GO:0043406=NAS, GO:0030198=TAS, GO:0045079=IDA, GO:0030574=TAS, GO:0006508=IDA, GO:0030141=IDA, GO:0009411=IDA, GO:0008201=IDA, GO:0009986=IDA, GO:0045415=IDA, GO:0045416=IDA, GO:0006874=NAS, GO:0005576=TAS, GO:0048661=IDA, GO:0051635=NAS, GO:0019955=IPI, GO:0004175=IDA, GO:0050728=NAS, GO:0008233=IDA} cellular calcium ion homeostasis, collagen catabolic process, extracellular matrix disassembly, extracellular matrix organization, negative regulation of chemokine biosynthetic process, negative regulation of chemotaxis, negative regulation of inflammatory response, negative regulation of interleukin-8 biosynthetic process, positive regulation of MAP kinase activity, positive regulation of interleukin-8 biosynthetic process, positive regulation of smooth muscle cell proliferation, protein catabolic process, proteolysis, response to UV cell surface, extracellular region, secretory granule bacterial cell surface binding, cytokine binding, endopeptidase activity, heparin binding, peptidase activity, protease binding, protein binding, serine-type endopeptidase activity Human ELAVL1 Reactome UniProtKB {GO:0005515=PMID:17932509, GO:0010467=Reactome:REACT_71, GO:0016070=Reactome:REACT_21257, GO:0019901=PMID:14517288, GO:0016071=Reactome:REACT_20605, GO:0003723=PMID:21613615, GO:0005634=PMID:14517288, GO:0007275=PMID:9003489, GO:0045727=PMID:21613615, GO:0003729=PMID:10660597, GO:0035925=PMID:23056314, GO:0006417=PMID:23056314, GO:0005829=Reactome:REACT_24924, GO:0005737=PMID:14517288, GO:0000166=GO_REF:0000002, GO:0017091=PMID:14517288, GO:0005654=Reactome:REACT_25286, GO:0048255=PMID:21613615, GO:0070935=PMID:14517288} Q15717 ELAV-like protein 1 protein 20091216 {GO:0005515=IPI, GO:0010467=TAS, GO:0016070=TAS, GO:0019901=IPI, GO:0016071=TAS, GO:0003723=IDA, GO:0005634=IDA, GO:0007275=TAS, GO:0045727=IDA, GO:0003729=TAS, GO:0035925=IDA, GO:0006417=IMP, GO:0005829=TAS, GO:0005737=IDA, GO:0000166=IEA, GO:0017091=IDA, GO:0005654=TAS, GO:0048255=IDA, GO:0070935=IDA} 3'-UTR-mediated mRNA stabilization, RNA metabolic process, gene expression, mRNA metabolic process, mRNA stabilization, multicellular organismal development, positive regulation of translation, regulation of translation cytoplasm, cytosol, nucleoplasm, nucleus AU-rich element binding, RNA binding, mRNA 3'-UTR AU-rich region binding, mRNA binding, nucleotide binding, protein binding, protein kinase binding Human ELAVL2 PINC UniProtKB {GO:0005515=PMID:17289661, GO:0006355=PMID:8158249, GO:0000166=GO_REF:0000002, GO:0003723=GO_REF:0000038, GO:0003730=PMID:8158249} Q12926 ELAV-like protein 2 protein 20030904 {GO:0005515=IPI, GO:0006355=TAS, GO:0000166=IEA, GO:0003723=IEA, GO:0003730=TAS} regulation of transcription, DNA-dependent RNA binding, mRNA 3'-UTR binding, nucleotide binding, protein binding Human ELAVL3 UniProtKB UniProtKB {GO:0000166=GO_REF:0000002, GO:0017091=PMID:10710437, GO:0003676=GO_REF:0000002, GO:0030154=GO_REF:0000037, GO:0007399=GO_REF:0000037} Q14576 ELAV-like protein 3 protein 20090731 {GO:0000166=IEA, GO:0017091=IDA, GO:0003676=IEA, GO:0030154=IEA, GO:0007399=IEA} cell differentiation, nervous system development AU-rich element binding, nucleic acid binding, nucleotide binding Human ELAVL4 PINC UniProtKB {GO:0006397=PMID:10348344, GO:0006396=PMID:1655278, GO:0000166=GO_REF:0000002, GO:0003723=PMID:1655278, GO:0017091=PMID:10710437, GO:0003730=PMID:10848602} P26378 ELAV-like protein 4 protein 20030904 {GO:0006397=TAS, GO:0006396=TAS, GO:0000166=IEA, GO:0003723=TAS, GO:0017091=IDA, GO:0003730=TAS} RNA processing, mRNA processing AU-rich element binding, RNA binding, mRNA 3'-UTR binding, nucleotide binding Human ELF1 ENSEMBL UniProtKB {GO:0005515=PMID:18692240, GO:0043565=GO_REF:0000002, GO:0005737=GO_REF:0000052, GO:0003700=PMID:14970218, GO:0045944=PMID:19674970, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000019, GO:0045893=PMID:19674970, GO:0001817=GO_REF:0000019, GO:0050860=GO_REF:0000019, GO:0006351=GO_REF:0000037} Q5T9E7 ETS-related transcription factor Elf-1 protein 20130413 {GO:0005515=IPI, GO:0043565=IEA, GO:0005737=IDA, GO:0003700=IDA, GO:0045944=IDA, GO:0005730=IDA, GO:0005634=IEA, GO:0045893=IDA, GO:0001817=IEA, GO:0050860=IEA, GO:0006351=IEA} negative regulation of T cell receptor signaling pathway, positive regulation of transcription from RNA polymerase II promoter, positive regulation of transcription, DNA-dependent, regulation of cytokine production, transcription, DNA-dependent cytoplasm, nucleolus, nucleus protein binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity Human Ensembl:ENSMUSP00000046515 ELF2 HPA UniProtKB {GO:0005515=PMID:14970218, GO:0043565=GO_REF:0000002, GO:0005737=GO_REF:0000052, GO:0003700=GO_REF:0000002, GO:0006357=PMID:8756667, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0045893=PMID:8756667, GO:0006351=GO_REF:0000037} Q15723 ETS-related transcription factor Elf-2 protein 20101115 {GO:0005515=IPI, GO:0043565=IEA, GO:0005737=IDA, GO:0003700=IEA, GO:0006357=IDA, GO:0005730=IDA, GO:0005634=IDA, GO:0045893=IDA, GO:0006351=IEA} positive regulation of transcription, DNA-dependent, regulation of transcription from RNA polymerase II promoter, transcription, DNA-dependent cytoplasm, nucleolus, nucleus protein binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity Human ELF3 HPA UniProtKB {GO:0005515=PMID:15075319, GO:0005794=GO_REF:0000052, GO:0003700=PMID:9234700, GO:0006366=PMID:9234700, GO:0060056=GO_REF:0000024, GO:0001824=GO_REF:0000019, GO:0003713=PMID:12624109, GO:0005730=GO_REF:0000052, GO:0007275=PMID:9234700, GO:0005634=GO_REF:0000052, GO:0043565=GO_REF:0000002, GO:0005737=GO_REF:0000052, GO:0006954=PMID:14715662, GO:0008544=PMID:9234700, GO:0030198=GO_REF:0000019, GO:0045944=GO_REF:0000019, GO:0030855=PMID:9234700, GO:0045893=PMID:9234700, GO:0045892=PMID:10773884} Q5SR36 ETS-related transcription factor Elf-3 protein 20101115 {GO:0005515=IPI, GO:0005794=IDA, GO:0003700=NAS, GO:0006366=TAS, GO:0060056=ISS, GO:0001824=IEA, GO:0003713=IDA, GO:0005730=IDA, GO:0007275=TAS, GO:0005634=IDA, GO:0043565=IEA, GO:0005737=IDA, GO:0006954=IEP, GO:0008544=NAS, GO:0030198=IEA, GO:0045944=IEA, GO:0030855=IEP, GO:0045893=IDA, GO:0045892=IDA} blastocyst development, epidermis development, epithelial cell differentiation, extracellular matrix organization, inflammatory response, mammary gland involution, multicellular organismal development, negative regulation of transcription, DNA-dependent, positive regulation of transcription from RNA polymerase II promoter, positive regulation of transcription, DNA-dependent, transcription from RNA polymerase II promoter Golgi apparatus, cytoplasm, nucleolus, nucleus protein binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, transcription coactivator activity Human ELF4 UniProtKB UniProtKB {GO:0005515=PMID:14970218, GO:0043565=GO_REF:0000002, GO:0006355=GO_REF:0000029, GO:0003700=GO_REF:0000029, GO:0016605=PMID:14970218, GO:0045944=PMID:14625302, GO:0001787=GO_REF:0000024, GO:0005634=GO_REF:0000029, GO:0045893=PMID:14625302, GO:0001866=GO_REF:0000024, GO:0006351=GO_REF:0000037} Q99607 ETS-related transcription factor Elf-4 protein 20060711 {GO:0005515=IPI, GO:0043565=IEA, GO:0006355=NAS, GO:0003700=NAS, GO:0016605=IDA, GO:0045944=IDA, GO:0001787=ISS, GO:0005634=NAS, GO:0045893=IDA, GO:0001866=ISS, GO:0006351=IEA} NK T cell proliferation, natural killer cell proliferation, positive regulation of transcription from RNA polymerase II promoter, positive regulation of transcription, DNA-dependent, regulation of transcription, DNA-dependent, transcription, DNA-dependent PML body, nucleus protein binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity Human UniProtKB:Q01196-1 ELF5 PINC UniProtKB {GO:0043565=GO_REF:0000002, GO:0005737=GO_REF:0000019, GO:0060644=GO_REF:0000019, GO:0003700=GO_REF:0000002, GO:0006366=PMID:9840936, GO:0008283=PMID:9840936, GO:0005634=GO_REF:0000039, GO:0007398=GO_REF:0000019} Q9UKW6 ETS-related transcription factor Elf-5 protein 20061106 {GO:0043565=IEA, GO:0005737=IEA, GO:0060644=IEA, GO:0003700=IEA, GO:0006366=TAS, GO:0008283=TAS, GO:0005634=IEA, GO:0007398=IEA} cell proliferation, ectoderm development, mammary gland epithelial cell differentiation, transcription from RNA polymerase II promoter cytoplasm, nucleus sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity Human ELFN1 UniProtKB UniProtKB {GO:0050808=GO_REF:0000024, GO:0019902=PMID:19389623, GO:0010923=PMID:19389623, GO:0004864=GO_REF:0000037, GO:0016021=GO_REF:0000037, GO:0060076=GO_REF:0000024, GO:0030425=GO_REF:0000024} P0C7U0 Protein ELFN1 protein 20121101 {GO:0050808=ISS, GO:0019902=IDA, GO:0010923=IDA, GO:0004864=IEA, GO:0016021=IEA, GO:0060076=ISS, GO:0030425=ISS} negative regulation of phosphatase activity, synapse organization dendrite, excitatory synapse, integral to membrane phosphatase binding, protein phosphatase inhibitor activity Human UniProtKB:Q8C8T7 ELFN2 UniProtKB UniProtKB {GO:0019902=PMID:19389623, GO:0010923=PMID:19389623, GO:0004864=GO_REF:0000037, GO:0016021=GO_REF:0000037} Q5R3F8 Protein phosphatase 1 regulatory subunit 29 protein 20111103 {GO:0019902=IDA, GO:0010923=IDA, GO:0004864=IEA, GO:0016021=IEA} negative regulation of phosphatase activity integral to membrane phosphatase binding, protein phosphatase inhibitor activity Human ELK1 BHF-UCL UniProtKB {GO:0005515=PMID:17296730, GO:0048011=Reactome:REACT_11061, GO:0038124=Reactome:REACT_8006, GO:0003700=PMID:14970218, GO:0034142=Reactome:REACT_6894, GO:0038123=Reactome:REACT_8005, GO:0034134=Reactome:REACT_7980, GO:0005634=PMID:20018936, GO:0002224=Reactome:REACT_9020, GO:0051403=Reactome:REACT_21308, GO:0006351=GO_REF:0000037, GO:0043565=GO_REF:0000002, GO:0002756=Reactome:REACT_6782, GO:0002755=Reactome:REACT_27215, GO:0045087=Reactome:REACT_6802, GO:0045944=PMID:22065586, GO:0035666=Reactome:REACT_25281, GO:0034166=Reactome:REACT_9027, GO:0045893=PMID:15790681, GO:0034146=Reactome:REACT_9061, GO:0034138=Reactome:REACT_6783, GO:0034162=Reactome:REACT_9047} P19419 ETS domain-containing protein Elk-1 protein 20110427 {GO:0005515=IPI, GO:0048011=TAS, GO:0038124=TAS, GO:0003700=IDA, GO:0034142=TAS, GO:0038123=TAS, GO:0034134=TAS, GO:0005634=IDA, GO:0002224=TAS, GO:0051403=TAS, GO:0006351=IEA, GO:0043565=IEA, GO:0002756=TAS, GO:0002755=TAS, GO:0045087=TAS, GO:0045944=IMP, GO:0035666=TAS, GO:0034166=TAS, GO:0045893=IDA, GO:0034146=TAS, GO:0034138=TAS, GO:0034162=TAS} MyD88-dependent toll-like receptor signaling pathway, MyD88-independent toll-like receptor signaling pathway, TRIF-dependent toll-like receptor signaling pathway, innate immune response, neurotrophin TRK receptor signaling pathway, positive regulation of transcription from RNA polymerase II promoter, positive regulation of transcription, DNA-dependent, stress-activated MAPK cascade, toll-like receptor 10 signaling pathway, toll-like receptor 2 signaling pathway, toll-like receptor 3 signaling pathway, toll-like receptor 4 signaling pathway, toll-like receptor 5 signaling pathway, toll-like receptor 9 signaling pathway, toll-like receptor TLR1:TLR2 signaling pathway, toll-like receptor TLR6:TLR2 signaling pathway, toll-like receptor signaling pathway, transcription, DNA-dependent nucleus protein binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity Human ELK3 HPA UniProtKB {GO:0005515=PMID:17474147, GO:0003700=GO_REF:0000019, GO:0003714=PMID:12933792, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0001525=GO_REF:0000019, GO:0032422=PMID:12933792, GO:0006351=GO_REF:0000037, GO:0043231=GO_REF:0000052, GO:0043565=GO_REF:0000002, GO:0005739=GO_REF:0000052, GO:0007165=PMID:7958835, GO:0042060=GO_REF:0000019, GO:0045892=PMID:12933792} P41970 ETS domain-containing protein Elk-3 protein 20080818 {GO:0005515=IPI, GO:0003700=IEA, GO:0003714=IDA, GO:0005730=IDA, GO:0005634=IDA, GO:0001525=IEA, GO:0032422=IDA, GO:0006351=IEA, GO:0043231=IDA, GO:0043565=IEA, GO:0005739=IDA, GO:0007165=TAS, GO:0042060=IEA, GO:0045892=IDA} angiogenesis, negative regulation of transcription, DNA-dependent, signal transduction, transcription, DNA-dependent, wound healing intracellular membrane-bounded organelle, mitochondrion, nucleolus, nucleus protein binding, purine-rich negative regulatory element binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, transcription corepressor activity Human ELK4 HPA UniProtKB {GO:0005515=PMID:22722849, GO:0003712=PMID:7851904, GO:0070932=PMID:22722849, GO:0003700=GO_REF:0000002, GO:0005730=GO_REF:0000052, GO:0001047=PMID:22722849, GO:0005634=GO_REF:0000052, GO:0000122=PMID:22722849, GO:0003677=PMID:1339307, GO:0006351=GO_REF:0000037, GO:0043565=GO_REF:0000002, GO:0005737=GO_REF:0000052, GO:0003682=PMID:22722849} P28324 ETS domain-containing protein Elk-4 protein 20101115 {GO:0005515=IPI, GO:0003712=TAS, GO:0070932=IDA, GO:0003700=IEA, GO:0005730=IDA, GO:0001047=TAS, GO:0005634=IDA, GO:0000122=IMP, GO:0003677=TAS, GO:0006351=IEA, GO:0043565=IEA, GO:0005737=IDA, GO:0003682=IDA} histone H3 deacetylation, negative regulation of transcription from RNA polymerase II promoter, transcription, DNA-dependent cytoplasm, nucleolus, nucleus DNA binding, chromatin binding, core promoter binding, protein binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, transcription cofactor activity Human ELL IntAct UniProtKB {GO:0005515=PMID:19389623, GO:0010467=Reactome:REACT_71, GO:0022415=Reactome:REACT_6361, GO:0006368=Reactome:REACT_1845, GO:0015030=GO_REF:0000039, GO:0006366=Reactome:REACT_1366, GO:0019902=PMID:19389623, GO:0008023=GO_REF:0000002, GO:0001701=GO_REF:0000019, GO:0050434=Reactome:REACT_6162, GO:0032786=PMID:8596958, GO:0016607=PMID:19389623, GO:0010923=PMID:19389623, GO:0016032=Reactome:REACT_6256, GO:0005654=Reactome:REACT_6355} P55199 RNA polymerase II elongation factor ELL protein 20130415 {GO:0005515=IPI, GO:0010467=TAS, GO:0022415=TAS, GO:0006368=TAS, GO:0015030=IEA, GO:0006366=TAS, GO:0019902=IDA, GO:0008023=IEA, GO:0001701=IEA, GO:0050434=TAS, GO:0032786=TAS, GO:0016607=IDA, GO:0010923=IDA, GO:0016032=TAS, GO:0005654=TAS} gene expression, in utero embryonic development, negative regulation of phosphatase activity, positive regulation of DNA-dependent transcription, elongation, positive regulation of viral transcription, transcription elongation from RNA polymerase II promoter, transcription from RNA polymerase II promoter, viral reproduction, viral reproductive process Cajal body, nuclear speck, nucleoplasm, transcription elongation factor complex phosphatase binding, protein binding Human UniProtKB:P62136 ELL2 HPA UniProtKB {GO:0006355=GO_REF:0000037, GO:0006368=GO_REF:0000002, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0003746=GO_REF:0000038, GO:0008023=GO_REF:0000002} O00472 RNA polymerase II elongation factor ELL2 protein 20110516 {GO:0006355=IEA, GO:0006368=IEA, GO:0005730=IDA, GO:0005634=IDA, GO:0003746=IEA, GO:0008023=IEA} regulation of transcription, DNA-dependent, transcription elongation from RNA polymerase II promoter nucleolus, nucleus, transcription elongation factor complex translation elongation factor activity NOT Human ELL3 HPA UniProtKB {GO:0048863=GO_REF:0000024, GO:0006368=PMID:10882741, GO:0032786=PMID:10882741, GO:0006354=PMID:10882741, GO:0006366=GO_REF:0000024, GO:0045944=PMID:10882741, GO:0005730=GO_REF:0000052, GO:0010717=GO_REF:0000024, GO:0005634=GO_REF:0000052, GO:0007283=PMID:10882741, GO:0008023=PMID:10882741, GO:0035326=GO_REF:0000024} Q9HB65 RNA polymerase II elongation factor ELL3 protein 20110516 {GO:0048863=ISS, GO:0006368=IDA, GO:0032786=IDA, GO:0006354=IDA, GO:0006366=ISS, GO:0045944=IDA, GO:0005730=IDA, GO:0010717=ISS, GO:0005634=IDA, GO:0007283=NAS, GO:0008023=NAS, GO:0035326=ISS} DNA-dependent transcription, elongation, positive regulation of DNA-dependent transcription, elongation, positive regulation of transcription from RNA polymerase II promoter, regulation of epithelial to mesenchymal transition, spermatogenesis, stem cell differentiation, transcription elongation from RNA polymerase II promoter, transcription from RNA polymerase II promoter nucleolus, nucleus, transcription elongation factor complex enhancer binding NOT Human ELMO1 IntAct UniProtKB {GO:0005515=PMID:15247908, GO:0006909=GO_REF:0000002, GO:0030029=GO_REF:0000019, GO:0017124=PMID:12029088, GO:0030036=PMID:11595183, GO:0005886=PMID:11595183, GO:0006928=PMID:11595183, GO:0006915=PMID:11595183, GO:0006911=PMID:11595183, GO:0050690=Reactome:REACT_11068, GO:0005829=Reactome:REACT_160134, GO:0016601=PMID:11595183, GO:0005737=GO_REF:0000054, GO:0005543=GO_REF:0000002, GO:0045087=Reactome:REACT_6802, GO:0016032=Reactome:REACT_6185, GO:0005856=GO_REF:0000002, GO:0038096=Reactome:REACT_160123} Q92556 Engulfment and cell motility protein 1 protein 20130415 {GO:0005515=IPI, GO:0006909=IEA, GO:0030029=IEA, GO:0017124=IPI, GO:0030036=IGI, GO:0005886=IDA, GO:0006928=IGI, GO:0006915=NAS, GO:0006911=IGI, GO:0050690=TAS, GO:0005829=TAS, GO:0016601=IGI, GO:0005737=IDA, GO:0005543=IEA, GO:0045087=TAS, GO:0016032=TAS, GO:0005856=IEA, GO:0038096=TAS} Fc-gamma receptor signaling pathway involved in phagocytosis, Rac protein signal transduction, actin cytoskeleton organization, actin filament-based process, apoptotic process, cellular component movement, innate immune response, phagocytosis, phagocytosis, engulfment, regulation of defense response to virus by virus, viral reproduction cytoplasm, cytoskeleton, cytosol, plasma membrane SH3 domain binding, phospholipid binding, protein binding Human UniProtKB:Q14185 ELMO2 Reactome UniProtKB {GO:0005515=PMID:20679435, GO:0006909=GO_REF:0000002, GO:0030971=PMID:20679435, GO:0017124=GO_REF:0000037, GO:0005543=GO_REF:0000002, GO:0016020=PMID:20679435, GO:0060326=PMID:20679435, GO:0045087=Reactome:REACT_6802, GO:0006915=GO_REF:0000037, GO:0005856=GO_REF:0000002, GO:0038096=Reactome:REACT_160123, GO:0005829=Reactome:REACT_160134} Q96JJ3 Engulfment and cell motility protein 2 protein 20130301 {GO:0005515=IPI, GO:0006909=IEA, GO:0030971=IPI, GO:0017124=IEA, GO:0005543=IEA, GO:0016020=IDA, GO:0060326=IMP, GO:0045087=TAS, GO:0006915=IEA, GO:0005856=IEA, GO:0038096=TAS, GO:0005829=TAS} Fc-gamma receptor signaling pathway involved in phagocytosis, apoptotic process, cell chemotaxis, innate immune response, phagocytosis cytoskeleton, cytosol, membrane SH3 domain binding, phospholipid binding, protein binding, receptor tyrosine kinase binding Human ELMO3 UniProtKB UniProtKB {GO:0006909=GO_REF:0000037, GO:0005737=GO_REF:0000039, GO:0017124=GO_REF:0000037, GO:0005543=GO_REF:0000002, GO:0006915=GO_REF:0000037, GO:0005856=GO_REF:0000002} Q96BJ8 Engulfment and cell motility protein 3 protein 20130413 {GO:0006909=IEA, GO:0005737=IEA, GO:0017124=IEA, GO:0005543=IEA, GO:0006915=IEA, GO:0005856=IEA} apoptotic process, phagocytosis cytoplasm, cytoskeleton SH3 domain binding, phospholipid binding Human UniProtKB-SubCell:SL-0086 ELMOD1 HPA UniProtKB {GO:0043547=PMID:17452337, GO:0006909=GO_REF:0000002, GO:0005737=GO_REF:0000052, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0005856=GO_REF:0000002, GO:0005096=PMID:17452337} Q8N336 ELMO domain-containing protein 1 protein 20111111 {GO:0043547=IDA, GO:0006909=IEA, GO:0005737=IDA, GO:0005730=IDA, GO:0005634=IDA, GO:0005856=IEA, GO:0005096=IDA} phagocytosis, positive regulation of GTPase activity cytoplasm, cytoskeleton, nucleolus, nucleus GTPase activator activity Human ELMOD2 GOC UniProtKB {GO:0043547=PMID:17452337, GO:0050688=PMID:17452337, GO:0006909=GO_REF:0000002, GO:0051607=GO_REF:0000037, GO:0005856=GO_REF:0000002, GO:0005096=PMID:17452337} Q8IZ81 ELMO domain-containing protein 2 protein 20130413 {GO:0043547=IDA, GO:0050688=IDA, GO:0006909=IEA, GO:0051607=IEA, GO:0005856=IEA, GO:0005096=IDA} defense response to virus, phagocytosis, positive regulation of GTPase activity, regulation of defense response to virus cytoskeleton GTPase activator activity Human ELN BHF-UCL UniProtKB {GO:0005515=PMID:11805834, GO:0007585=PMID:9873040, GO:0008283=PMID:9607766, GO:0008015=PMID:8096434, GO:0043149=GO_REF:0000019, GO:0005578=GO_REF:0000029, GO:0050840=GO_REF:0000019, GO:0005576=Reactome:REACT_150459, GO:0030023=GO_REF:0000029, GO:0071953=GO_REF:0000019, GO:0005739=GO_REF:0000019, GO:0030833=GO_REF:0000019, GO:0001974=GO_REF:0000019, GO:0007519=GO_REF:0000019, GO:0030198=Reactome:REACT_118779, GO:0009887=PMID:9580666, GO:0005201=PMID:9580666} P15502 Elastin protein 20101007 {GO:0005515=IPI, GO:0007585=TAS, GO:0008283=TAS, GO:0008015=TAS, GO:0043149=IEA, GO:0005578=NAS, GO:0050840=IEA, GO:0005576=TAS, GO:0030023=NAS, GO:0071953=IEA, GO:0005739=IEA, GO:0030833=IEA, GO:0001974=IEA, GO:0007519=IEA, GO:0030198=TAS, GO:0009887=TAS, GO:0005201=TAS} blood circulation, blood vessel remodeling, cell proliferation, extracellular matrix organization, organ morphogenesis, regulation of actin filament polymerization, respiratory gaseous exchange, skeletal muscle tissue development, stress fiber assembly elastic fiber, extracellular region, mitochondrion, proteinaceous extracellular matrix extracellular matrix binding, extracellular matrix constituent conferring elasticity, extracellular matrix structural constituent, protein binding Human UniProtKB:Q9WVH8 ELOF1 UniProtKB UniProtKB {GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0046872=GO_REF:0000037, GO:0006351=GO_REF:0000037} P60002 Transcription elongation factor 1 homolog protein 20130413 {GO:0006355=IEA, GO:0005634=IEA, GO:0046872=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus metal ion binding Human UniProtKB-SubCell:SL-0191 ELOVL1 Reactome UniProtKB {GO:0005515=PMID:20937905, GO:0005783=PMID:20937905, GO:0019367=PMID:20166112, GO:0030148=PMID:20937905, GO:0030176=PMID:20166112, GO:0035338=Reactome:REACT_1319, GO:0044281=Reactome:REACT_111217, GO:0009922=PMID:20166112, GO:0005789=Reactome:REACT_22270, GO:0019432=Reactome:REACT_1190, GO:0034625=PMID:20166112, GO:0042761=PMID:20166112, GO:0044255=Reactome:REACT_22279} Q9BW60 Elongation of very long chain fatty acids protein 1 protein 20130301 {GO:0005515=IPI, GO:0005783=IDA, GO:0019367=IDA, GO:0030148=IMP, GO:0030176=NAS, GO:0035338=TAS, GO:0044281=TAS, GO:0009922=IDA, GO:0005789=TAS, GO:0019432=TAS, GO:0034625=IDA, GO:0042761=IDA, GO:0044255=TAS} cellular lipid metabolic process, fatty acid elongation, monounsaturated fatty acid, fatty acid elongation, saturated fatty acid, long-chain fatty-acyl-CoA biosynthetic process, small molecule metabolic process, sphingolipid biosynthetic process, triglyceride biosynthetic process, very long-chain fatty acid biosynthetic process endoplasmic reticulum, endoplasmic reticulum membrane, integral to endoplasmic reticulum membrane fatty acid elongase activity, protein binding Human ELOVL2 Reactome UniProtKB {GO:0005515=PMID:20937905, GO:0005783=PMID:20937905, GO:0044281=Reactome:REACT_111217, GO:0035338=Reactome:REACT_1319, GO:0036109=Reactome:REACT_121147, GO:0033559=Reactome:REACT_121284, GO:0043651=Reactome:REACT_121100, GO:0009922=PMID:12371743, GO:0005789=Reactome:REACT_121099, GO:0019432=Reactome:REACT_1190, GO:0016021=GO_REF:0000037, GO:0034626=PMID:20937905, GO:0042761=PMID:20937905, GO:0044255=Reactome:REACT_22279} Q9NXB9 Elongation of very long chain fatty acids protein 2 protein 20130301 {GO:0005515=IPI, GO:0005783=IDA, GO:0044281=TAS, GO:0035338=TAS, GO:0036109=TAS, GO:0033559=TAS, GO:0043651=TAS, GO:0009922=IDA, GO:0005789=TAS, GO:0019432=TAS, GO:0016021=IEA, GO:0034626=IDA, GO:0042761=IDA, GO:0044255=TAS} alpha-linolenic acid metabolic process, cellular lipid metabolic process, fatty acid elongation, polyunsaturated fatty acid, linoleic acid metabolic process, long-chain fatty-acyl-CoA biosynthetic process, small molecule metabolic process, triglyceride biosynthetic process, unsaturated fatty acid metabolic process, very long-chain fatty acid biosynthetic process endoplasmic reticulum, endoplasmic reticulum membrane, integral to membrane fatty acid elongase activity, protein binding Human ELOVL3 Reactome UniProtKB {GO:0005515=PMID:20937905, GO:0005783=PMID:20937905, GO:0019367=PMID:20937905, GO:0035338=Reactome:REACT_1319, GO:0044281=Reactome:REACT_111217, GO:0005789=Reactome:REACT_22133, GO:0019432=Reactome:REACT_1190, GO:0034625=PMID:20937905, GO:0016021=GO_REF:0000037, GO:0034626=PMID:20937905, GO:0042761=PMID:20937905, GO:0016740=GO_REF:0000037, GO:0044255=Reactome:REACT_22279} Q9HB03 Elongation of very long chain fatty acids protein 3 protein 20130301 {GO:0005515=IPI, GO:0005783=IDA, GO:0019367=IDA, GO:0035338=TAS, GO:0044281=TAS, GO:0005789=TAS, GO:0019432=TAS, GO:0034625=IDA, GO:0016021=IEA, GO:0034626=IDA, GO:0042761=IDA, GO:0016740=IEA, GO:0044255=TAS} cellular lipid metabolic process, fatty acid elongation, monounsaturated fatty acid, fatty acid elongation, polyunsaturated fatty acid, fatty acid elongation, saturated fatty acid, long-chain fatty-acyl-CoA biosynthetic process, small molecule metabolic process, triglyceride biosynthetic process, very long-chain fatty acid biosynthetic process endoplasmic reticulum, endoplasmic reticulum membrane, integral to membrane protein binding, transferase activity Human ELOVL4 GOC UniProtKB {GO:0005515=PMID:20937905, GO:0005783=PMID:20937905, GO:0019367=PMID:20937905, GO:0030176=PMID:16036915, GO:0035338=Reactome:REACT_1319, GO:0044281=Reactome:REACT_111217, GO:0008020=PMID:11138005, GO:0009584=PMID:11138005, GO:0019432=Reactome:REACT_1190, GO:0006633=PMID:11138005, GO:0042761=GO_REF:0000024, GO:0016740=GO_REF:0000037, GO:0044255=Reactome:REACT_22279} Q9GZR5 Elongation of very long chain fatty acids protein 4 protein 20130413 {GO:0005515=IPI, GO:0005783=IDA, GO:0019367=IDA, GO:0030176=IDA, GO:0035338=TAS, GO:0044281=TAS, GO:0008020=NAS, GO:0009584=NAS, GO:0019432=TAS, GO:0006633=NAS, GO:0042761=ISS, GO:0016740=IEA, GO:0044255=TAS} cellular lipid metabolic process, detection of visible light, fatty acid biosynthetic process, fatty acid elongation, saturated fatty acid, long-chain fatty-acyl-CoA biosynthetic process, small molecule metabolic process, triglyceride biosynthetic process, very long-chain fatty acid biosynthetic process endoplasmic reticulum, integral to endoplasmic reticulum membrane G-protein coupled photoreceptor activity, protein binding, transferase activity Human ELOVL5 Reactome UniProtKB {GO:0005515=PMID:20937905, GO:0005783=PMID:20937905, GO:0044281=Reactome:REACT_111217, GO:0035338=Reactome:REACT_1319, GO:0036109=Reactome:REACT_121147, GO:0033559=Reactome:REACT_121284, GO:0043651=Reactome:REACT_121100, GO:0009922=PMID:20427700, GO:0005789=Reactome:REACT_121099, GO:0019432=Reactome:REACT_1190, GO:0034625=PMID:20427700, GO:0016021=GO_REF:0000037, GO:0034626=PMID:20937905, GO:0042761=PMID:20937905, GO:0044255=Reactome:REACT_22279} Q9NYP7 Elongation of very long chain fatty acids protein 5 protein 20130301 {GO:0005515=IPI, GO:0005783=IDA, GO:0044281=TAS, GO:0035338=TAS, GO:0036109=TAS, GO:0033559=TAS, GO:0043651=TAS, GO:0009922=IDA, GO:0005789=TAS, GO:0019432=TAS, GO:0034625=IDA, GO:0016021=IEA, GO:0034626=IDA, GO:0042761=IDA, GO:0044255=TAS} alpha-linolenic acid metabolic process, cellular lipid metabolic process, fatty acid elongation, monounsaturated fatty acid, fatty acid elongation, polyunsaturated fatty acid, linoleic acid metabolic process, long-chain fatty-acyl-CoA biosynthetic process, small molecule metabolic process, triglyceride biosynthetic process, unsaturated fatty acid metabolic process, very long-chain fatty acid biosynthetic process endoplasmic reticulum, endoplasmic reticulum membrane, integral to membrane fatty acid elongase activity, protein binding Human ELOVL6 Reactome UniProtKB {GO:0005515=PMID:20937905, GO:0016747=GO_REF:0000019, GO:0005783=PMID:20937905, GO:0019367=PMID:20937905, GO:0030497=GO_REF:0000019, GO:0030176=GO_REF:0000019, GO:0035338=Reactome:REACT_1319, GO:0044281=Reactome:REACT_111217, GO:0042759=PMID:20937905, GO:0005789=Reactome:REACT_147888, GO:0019432=Reactome:REACT_1190, GO:0016021=GO_REF:0000002, GO:0044255=Reactome:REACT_22279} Q9H5J4 Elongation of very long chain fatty acids protein 6 protein 20130301 {GO:0005515=IPI, GO:0016747=IEA, GO:0005783=IDA, GO:0019367=IDA, GO:0030497=IEA, GO:0030176=IEA, GO:0035338=TAS, GO:0044281=TAS, GO:0042759=IDA, GO:0005789=TAS, GO:0019432=TAS, GO:0016021=IEA, GO:0044255=TAS} cellular lipid metabolic process, fatty acid elongation, fatty acid elongation, saturated fatty acid, long-chain fatty acid biosynthetic process, long-chain fatty-acyl-CoA biosynthetic process, small molecule metabolic process, triglyceride biosynthetic process endoplasmic reticulum, endoplasmic reticulum membrane, integral to endoplasmic reticulum membrane, integral to membrane protein binding, transferase activity, transferring acyl groups other than amino-acyl groups Human ELOVL7 InterPro UniProtKB {GO:0005515=PMID:20937905, GO:0005783=PMID:20937905, GO:0019367=PMID:19826053, GO:0019432=Reactome:REACT_1190, GO:0005789=Reactome:REACT_22192, GO:0044281=Reactome:REACT_111217, GO:0035338=Reactome:REACT_1319, GO:0034626=PMID:20937905, GO:0016021=GO_REF:0000002, GO:0042761=PMID:19826053, GO:0044255=Reactome:REACT_22279, GO:0016740=GO_REF:0000037} D6RHD0 Elongation of very long chain fatty acids protein 7 protein 20130413 {GO:0005515=IPI, GO:0005783=IDA, GO:0019367=IDA, GO:0019432=TAS, GO:0005789=TAS, GO:0044281=TAS, GO:0035338=TAS, GO:0034626=IDA, GO:0016021=IEA, GO:0042761=IDA, GO:0044255=TAS, GO:0016740=IEA} cellular lipid metabolic process, fatty acid elongation, polyunsaturated fatty acid, fatty acid elongation, saturated fatty acid, long-chain fatty-acyl-CoA biosynthetic process, small molecule metabolic process, triglyceride biosynthetic process, very long-chain fatty acid biosynthetic process endoplasmic reticulum, endoplasmic reticulum membrane, integral to membrane protein binding, transferase activity Human InterPro:IPR002076 ELP2 HPA UniProtKB {GO:0006368=PMID:11714725, GO:0005737=GO_REF:0000052, GO:0033588=PMID:22854966, GO:0006357=PMID:11714725, GO:0016591=PMID:11714725, GO:0005730=PMID:11714725, GO:0008023=PMID:11714725, GO:0003677=PMID:11714725} Q6IA86 Elongator complex protein 2 protein 20101115 {GO:0006368=IC, GO:0005737=IDA, GO:0033588=IDA, GO:0006357=TAS, GO:0016591=IC, GO:0005730=IC, GO:0008023=IDA, GO:0003677=IDA} regulation of transcription from RNA polymerase II promoter, transcription elongation from RNA polymerase II promoter DNA-directed RNA polymerase II, holoenzyme, Elongator holoenzyme complex, cytoplasm, nucleolus, transcription elongation factor complex DNA binding Human ELP3 IntAct UniProtKB {GO:0005515=PMID:19185337, GO:0006368=PMID:11714725, GO:0008080=GO_REF:0000002, GO:0030335=GO_REF:0000024, GO:0051536=GO_REF:0000037, GO:0006357=PMID:11714725, GO:0005730=PMID:11714725, GO:0008023=PMID:11714725, GO:0003677=PMID:11714725, GO:0046872=GO_REF:0000037, GO:0005737=GO_REF:0000054, GO:0033588=PMID:22854966, GO:0016591=PMID:11714725, GO:0008607=PMID:11818576, GO:0004402=GO_REF:0000003} Q9H9T3 Elongator complex protein 3 protein 20130415 {GO:0005515=IPI, GO:0006368=IDA, GO:0008080=IEA, GO:0030335=ISS, GO:0051536=IEA, GO:0006357=TAS, GO:0005730=IDA, GO:0008023=IDA, GO:0003677=IDA, GO:0046872=IEA, GO:0005737=IDA, GO:0033588=IDA, GO:0016591=IDA, GO:0008607=IDA, GO:0004402=IEA} positive regulation of cell migration, regulation of transcription from RNA polymerase II promoter, transcription elongation from RNA polymerase II promoter DNA-directed RNA polymerase II, holoenzyme, Elongator holoenzyme complex, cytoplasm, nucleolus, transcription elongation factor complex DNA binding, N-acetyltransferase activity, histone acetyltransferase activity, iron-sulfur cluster binding, metal ion binding, phosphorylase kinase regulator activity, protein binding Human UniProtKB:O95163 ELP4 GOC UniProtKB {GO:0005515=PMID:17577209, GO:0006368=PMID:11714725, GO:0005737=PMID:22854966, GO:0033588=PMID:11714725, GO:0016573=PMID:11714725, GO:0006357=PMID:11714725, GO:0016591=PMID:11714725, GO:0008607=PMID:11818576, GO:0008023=PMID:11714725, GO:0004402=PMID:11714725} Q96EB1 Elongator complex protein 4 protein 20130413 {GO:0005515=IPI, GO:0006368=IC, GO:0005737=IDA, GO:0033588=IDA, GO:0016573=IDA, GO:0006357=TAS, GO:0016591=IDA, GO:0008607=IDA, GO:0008023=IDA, GO:0004402=IDA} histone acetylation, regulation of transcription from RNA polymerase II promoter, transcription elongation from RNA polymerase II promoter DNA-directed RNA polymerase II, holoenzyme, Elongator holoenzyme complex, cytoplasm, transcription elongation factor complex histone acetyltransferase activity, phosphorylase kinase regulator activity, protein binding Human ELSPBP1 UniProtKB UniProtKB {GO:0007338=GO_REF:0000037, GO:0005576=GO_REF:0000039} Q96BH3 Epididymal sperm-binding protein 1 protein 20130413 {GO:0007338=IEA, GO:0005576=IEA} single fertilization extracellular region Human UniProtKB-SubCell:SL-0243 ELTD1 GDB UniProtKB {GO:0007186=PMID:15203201, GO:0005886=GO_REF:0000039, GO:0007218=GO_REF:0000002, GO:0004930=GO_REF:0000037, GO:0005509=GO_REF:0000002, GO:0046983=GO_REF:0000019, GO:0016021=GO_REF:0000037} Q9HBW9 EGF, latrophilin and seven transmembrane domain-containing protein 1 protein 20050504 {GO:0007186=TAS, GO:0005886=IEA, GO:0007218=IEA, GO:0004930=IEA, GO:0005509=IEA, GO:0046983=IEA, GO:0016021=IEA} G-protein coupled receptor signaling pathway, neuropeptide signaling pathway integral to membrane, plasma membrane G-protein coupled receptor activity, calcium ion binding, protein dimerization activity Human EMB ENSEMBL UniProtKB {GO:0016021=GO_REF:0000037, GO:0007155=GO_REF:0000019} Q6PCB8 Embigin protein 20130413 {GO:0016021=IEA, GO:0007155=IEA} cell adhesion integral to membrane Human Ensembl:ENSRNOP00000015306 EMC4 UniProtKB UniProtKB {GO:0072546=PMID:22119785, GO:0006915=GO_REF:0000037, GO:0016021=PMID:22119785} Q5J8M3 ER membrane protein complex subunit 4 protein 20120629 {GO:0072546=IDA, GO:0006915=IEA, GO:0016021=IDA} apoptotic process ER membrane protein complex, integral to membrane Human EMCN UniProtKB UniProtKB {GO:0005886=GO_REF:0000039, GO:0005576=GO_REF:0000039, GO:0016021=GO_REF:0000037} Q9ULC0 Endomucin protein 20130413 {GO:0005886=IEA, GO:0005576=IEA, GO:0016021=IEA} extracellular region, integral to membrane, plasma membrane Human UniProtKB-SubCell:SL-0039 EMD HPA UniProtKB {GO:0007077=Reactome:REACT_160255, GO:0005515=PMID:16169070, GO:0031965=GO_REF:0000052, GO:0005783=GO_REF:0000052, GO:0007084=Reactome:REACT_160113, GO:0005874=GO_REF:0000037, GO:0048147=PMID:16858403, GO:0048487=PMID:17785515, GO:0005637=PMID:16858403, GO:0003779=PMID:15328537, GO:0005635=PMID:16858403, GO:0035914=GO_REF:0000019, GO:0035414=PMID:16858403, GO:0060828=PMID:16858403, GO:0046827=PMID:16858403, GO:0005640=PMID:17785515, GO:0006936=PMID:7894480, GO:0007517=PMID:8589715, GO:0071363=PMID:16858403, GO:0000088=Reactome:REACT_765, GO:0000087=Reactome:REACT_910, GO:0016021=GO_REF:0000037, GO:0000278=Reactome:REACT_152, GO:0000090=Reactome:REACT_1275} Q5HY57 Emerin (Emery-Dreifuss muscular dystrophy), isoform CRA_b protein 20080205 {GO:0007077=TAS, GO:0005515=IPI, GO:0031965=IDA, GO:0005783=IDA, GO:0007084=TAS, GO:0005874=IEA, GO:0048147=IMP, GO:0048487=IDA, GO:0005637=NAS, GO:0003779=IDA, GO:0005635=IDA, GO:0035914=IEA, GO:0035414=IMP, GO:0060828=IMP, GO:0046827=IMP, GO:0005640=IDA, GO:0006936=TAS, GO:0007517=TAS, GO:0071363=IMP, GO:0000088=TAS, GO:0000087=TAS, GO:0016021=IEA, GO:0000278=TAS, GO:0000090=TAS} M phase of mitotic cell cycle, cellular response to growth factor stimulus, mitotic anaphase, mitotic cell cycle, mitotic nuclear envelope disassembly, mitotic nuclear envelope reassembly, mitotic prophase, muscle contraction, muscle organ development, negative regulation of catenin import into nucleus, negative regulation of fibroblast proliferation, positive regulation of protein export from nucleus, regulation of canonical Wnt receptor signaling pathway, skeletal muscle cell differentiation endoplasmic reticulum, integral to membrane, microtubule, nuclear envelope, nuclear inner membrane, nuclear membrane, nuclear outer membrane actin binding, beta-tubulin binding, protein binding Human EME1 IntAct UniProtKB {GO:0005515=PMID:19596236, GO:0004518=GO_REF:0000002, GO:0006281=GO_REF:0000037, GO:0004519=GO_REF:0000037, GO:0005730=GO_REF:0000039, GO:0006310=GO_REF:0000037, GO:0006259=GO_REF:0000002, GO:0003677=GO_REF:0000002, GO:0046872=GO_REF:0000037} Q96AY2 Crossover junction endonuclease EME1 protein 20130415 {GO:0005515=IPI, GO:0004518=IEA, GO:0006281=IEA, GO:0004519=IEA, GO:0005730=IEA, GO:0006310=IEA, GO:0006259=IEA, GO:0003677=IEA, GO:0046872=IEA} DNA metabolic process, DNA recombination, DNA repair nucleolus DNA binding, endonuclease activity, metal ion binding, nuclease activity, protein binding Human UniProtKB:Q8IY92 EME2 InterPro UniProtKB {GO:0004518=GO_REF:0000002, GO:0006281=GO_REF:0000037, GO:0004519=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0006310=GO_REF:0000037, GO:0006259=GO_REF:0000002, GO:0003677=GO_REF:0000002} H3BV62 Probable crossover junction endonuclease EME2 protein 20130413 {GO:0004518=IEA, GO:0006281=IEA, GO:0004519=IEA, GO:0005634=IEA, GO:0006310=IEA, GO:0006259=IEA, GO:0003677=IEA} DNA metabolic process, DNA recombination, DNA repair nucleus DNA binding, endonuclease activity, nuclease activity Human InterPro:IPR006166 EMG1 UniProtKB UniProtKB {GO:0070037=PMID:20047967, GO:0005737=GO_REF:0000024, GO:0006364=GO_REF:0000024, GO:0003723=GO_REF:0000024, GO:0005730=GO_REF:0000024, GO:0005634=GO_REF:0000024, GO:0042274=GO_REF:0000024, GO:0019843=GO_REF:0000037} Q92979 Ribosomal RNA small subunit methyltransferase NEP1 protein 20091117 {GO:0070037=IDA, GO:0005737=ISS, GO:0006364=ISS, GO:0003723=ISS, GO:0005730=ISS, GO:0005634=ISS, GO:0042274=ISS, GO:0019843=IEA} rRNA processing, ribosomal small subunit biogenesis cytoplasm, nucleolus, nucleus RNA binding, rRNA (pseudouridine) methyltransferase activity, rRNA binding Human UniProtKB:Q06287 EMID1 ENSEMBL UniProtKB {GO:0005581=GO_REF:0000037, GO:0005794=GO_REF:0000019, GO:0005783=GO_REF:0000019, GO:0005578=GO_REF:0000019} Q96A84 EMI domain-containing protein 1 protein 20130413 {GO:0005581=IEA, GO:0005794=IEA, GO:0005783=IEA, GO:0005578=IEA} Golgi apparatus, collagen, endoplasmic reticulum, proteinaceous extracellular matrix Human Ensembl:ENSMUSP00000061704 EMILIN1 Reactome UniProtKB {GO:0005515=PMID:11278945, GO:0005581=GO_REF:0000037, GO:0030198=Reactome:REACT_118779, GO:0010811=GO_REF:0000019, GO:0005576=Reactome:REACT_150335, GO:0030023=GO_REF:0000019, GO:0007155=GO_REF:0000037, GO:0042802=GO_REF:0000019} Q9Y6C2 EMILIN-1 protein 20130213 {GO:0005515=IPI, GO:0005581=IEA, GO:0030198=TAS, GO:0010811=IEA, GO:0005576=TAS, GO:0030023=IEA, GO:0007155=IEA, GO:0042802=IEA} cell adhesion, extracellular matrix organization, positive regulation of cell-substrate adhesion collagen, extracellular region extracellular matrix constituent conferring elasticity, identical protein binding, protein binding Human EMILIN2 UniProtKB UniProtKB {GO:0005515=PMID:11278945, GO:0008150=GO_REF:0000015, GO:0005581=GO_REF:0000037, GO:0030023=PMID:11278945, GO:0005576=PMID:11278945, GO:0007155=GO_REF:0000037} Q9BXX0 EMILIN-2 protein 20061026 {GO:0005515=IPI, GO:0008150=ND, GO:0005581=IEA, GO:0030023=NAS, GO:0005576=IDA, GO:0007155=IEA} biological_process, cell adhesion collagen, extracellular region extracellular matrix constituent conferring elasticity, protein binding Human EMILIN3 BHF-UCL UniProtKB {GO:0031012=PMID:22261194, GO:0005737=GO_REF:0000019, GO:0005578=GO_REF:0000039} Q9NT22 EMILIN-3 protein 20120228 {GO:0031012=ISS, GO:0005737=IEA, GO:0005578=IEA} cytoplasm, extracellular matrix, proteinaceous extracellular matrix colocalizes_with Human UniProtKB:F1SDV5 EML1 IntAct UniProtKB {GO:0005515=PMID:19060904, GO:0005737=GO_REF:0000037, GO:0005875=PMID:9226380, GO:0005509=PMID:9226380, GO:0005874=GO_REF:0000037} O00423 Echinoderm microtubule-associated protein-like 1 protein 20130415 {GO:0005515=IPI, GO:0005737=IEA, GO:0005875=TAS, GO:0005509=NAS, GO:0005874=IEA} cytoplasm, microtubule, microtubule associated complex calcium ion binding, protein binding Human UniProtKB:Q9H9L3 EML2 HPA UniProtKB {GO:0005737=GO_REF:0000037, GO:0005875=PMID:10521658, GO:0007605=PMID:10521658, GO:0005874=GO_REF:0000037, GO:0005102=GO_REF:0000019, GO:0008022=GO_REF:0000019, GO:0003824=GO_REF:0000002, GO:0007601=PMID:10521658, GO:0043231=GO_REF:0000052} O95834 Echinoderm microtubule-associated protein-like 2 protein 20081203 {GO:0005737=IEA, GO:0005875=TAS, GO:0007605=TAS, GO:0005874=IEA, GO:0005102=IEA, GO:0008022=IEA, GO:0003824=IEA, GO:0007601=TAS, GO:0043231=IDA} sensory perception of sound, visual perception cytoplasm, intracellular membrane-bounded organelle, microtubule, microtubule associated complex catalytic activity, protein C-terminus binding, receptor binding Human EML3 UniProtKB UniProtKB {GO:0005737=GO_REF:0000037, GO:0005874=GO_REF:0000037} Q32P44 Echinoderm microtubule-associated protein-like 3 protein 20130413 {GO:0005737=IEA, GO:0005874=IEA} cytoplasm, microtubule Human UniProtKB-KW:KW-0493 EML4 UniProtKB UniProtKB {GO:0003674=GO_REF:0000015, GO:0007067=PMID:10995578, GO:0005737=PMID:10995578, GO:0005874=GO_REF:0000037, GO:0007017=PMID:10995578} Q9HC35 Echinoderm microtubule-associated protein-like 4 protein 20021114 {GO:0003674=ND, GO:0007067=NAS, GO:0005737=NAS, GO:0005874=IEA, GO:0007017=NAS} microtubule-based process, mitosis cytoplasm, microtubule molecular_function Human EMP2 MGI UniProtKB {GO:2001046=PMID:16216233, GO:0005178=PMID:16216233, GO:0008283=PMID:8996089, GO:0016021=GO_REF:0000037, GO:0001954=PMID:16216233} P54851 Epithelial membrane protein 2 protein 20130220 {GO:2001046=IDA, GO:0005178=IPI, GO:0008283=TAS, GO:0016021=IEA, GO:0001954=IDA} cell proliferation, positive regulation of cell-matrix adhesion, positive regulation of integrin-mediated signaling pathway integral to membrane integrin binding Human EMP3 PINC UniProtKB {GO:0008285=PMID:8996089, GO:0016020=GO_REF:0000002, GO:0016049=GO_REF:0000002, GO:0016021=GO_REF:0000037} P54852 Epithelial membrane protein 3 protein 20030904 {GO:0008285=TAS, GO:0016020=IEA, GO:0016049=IEA, GO:0016021=IEA} cell growth, negative regulation of cell proliferation integral to membrane, membrane Human EMR2 Reactome UniProtKB {GO:0031256=PMID:17928360, GO:0005886=Reactome:REACT_23776, GO:0004930=GO_REF:0000037, GO:0005509=GO_REF:0000002, GO:0071621=PMID:17928360, GO:0032587=GO_REF:0000039, GO:0035374=PMID:12829604, GO:0006954=GO_REF:0000037, GO:0007186=PMID:15203201, GO:0016020=GO_REF:0000002, GO:0016477=PMID:17928360, GO:0007218=GO_REF:0000002, GO:0016021=GO_REF:0000037, GO:0007155=PMID:12829604} Q9UHX3 EGF-like module-containing mucin-like hormone receptor-like 2 protein 20091026 {GO:0031256=IDA, GO:0005886=TAS, GO:0004930=IEA, GO:0005509=IEA, GO:0071621=IMP, GO:0032587=IEA, GO:0035374=IMP, GO:0006954=IEA, GO:0007186=TAS, GO:0016020=IEA, GO:0016477=IMP, GO:0007218=IEA, GO:0016021=IEA, GO:0007155=IMP} G-protein coupled receptor signaling pathway, cell adhesion, cell migration, granulocyte chemotaxis, inflammatory response, neuropeptide signaling pathway integral to membrane, leading edge membrane, membrane, plasma membrane, ruffle membrane G-protein coupled receptor activity, calcium ion binding, chondroitin sulfate binding Human EMX1 MGI UniProtKB {GO:0005515=PMID:20887964, GO:0043565=GO_REF:0000002, GO:0005737=GO_REF:0000039, GO:0021796=GO_REF:0000019, GO:0003700=GO_REF:0000002, GO:0042493=GO_REF:0000019, GO:0030182=GO_REF:0000019, GO:0007275=GO_REF:0000029, GO:0005634=PMID:20887964, GO:0009791=GO_REF:0000019, GO:0003677=GO_REF:0000029} Q04741 Homeobox protein EMX1 protein 20120406 {GO:0005515=IPI, GO:0043565=IEA, GO:0005737=IEA, GO:0021796=IEA, GO:0003700=IEA, GO:0042493=IEA, GO:0030182=IEA, GO:0007275=NAS, GO:0005634=IDA, GO:0009791=IEA, GO:0003677=NAS} cerebral cortex regionalization, multicellular organismal development, neuron differentiation, post-embryonic development, response to drug cytoplasm, nucleus DNA binding, protein binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity Human EMX2 IntAct UniProtKB {GO:0005515=PMID:15247416, GO:0021542=GO_REF:0000019, GO:0021846=GO_REF:0000019, GO:0000976=GO_REF:0000002, GO:0003700=GO_REF:0000002, GO:0042493=GO_REF:0000019, GO:0007275=GO_REF:0000029, GO:0005634=GO_REF:0000029, GO:0009952=GO_REF:0000019, GO:0003677=GO_REF:0000029, GO:0021796=GO_REF:0000019, GO:0030182=GO_REF:0000019, GO:0072001=GO_REF:0000019, GO:0021885=GO_REF:0000019} Q04743 Homeobox protein EMX2 protein 20130415 {GO:0005515=IPI, GO:0021542=IEA, GO:0021846=IEA, GO:0000976=IEA, GO:0003700=IEA, GO:0042493=IEA, GO:0007275=NAS, GO:0005634=NAS, GO:0009952=IEA, GO:0003677=NAS, GO:0021796=IEA, GO:0030182=IEA, GO:0072001=IEA, GO:0021885=IEA} anterior/posterior pattern specification, cell proliferation in forebrain, cerebral cortex regionalization, dentate gyrus development, forebrain cell migration, multicellular organismal development, neuron differentiation, renal system development, response to drug nucleus DNA binding, protein binding, sequence-specific DNA binding transcription factor activity, transcription regulatory region sequence-specific DNA binding Human UniProtKB:P06730 EN1 PINC UniProtKB {GO:0003700=GO_REF:0000002, GO:0009954=GO_REF:0000019, GO:0005634=GO_REF:0000039, GO:0009953=GO_REF:0000019, GO:0009653=PMID:8094370, GO:0043565=GO_REF:0000002, GO:0001501=PMID:8684466, GO:0048666=GO_REF:0000019, GO:0045944=GO_REF:0000019, GO:0043473=GO_REF:0000019, GO:0030917=GO_REF:0000019, GO:0030901=GO_REF:0000019, GO:0035115=GO_REF:0000019, GO:0030902=GO_REF:0000019} Q05925 Homeobox protein engrailed-1 protein 20031119 {GO:0003700=IEA, GO:0009954=IEA, GO:0005634=IEA, GO:0009953=IEA, GO:0009653=TAS, GO:0043565=IEA, GO:0001501=TAS, GO:0048666=IEA, GO:0045944=IEA, GO:0043473=IEA, GO:0030917=IEA, GO:0030901=IEA, GO:0035115=IEA, GO:0030902=IEA} anatomical structure morphogenesis, dorsal/ventral pattern formation, embryonic forelimb morphogenesis, hindbrain development, midbrain development, midbrain-hindbrain boundary development, neuron development, pigmentation, positive regulation of transcription from RNA polymerase II promoter, proximal/distal pattern formation, skeletal system development nucleus sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity Human EN2 PINC UniProtKB {GO:0043565=GO_REF:0000002, GO:0003700=GO_REF:0000002, GO:0016020=GO_REF:0000019, GO:0048666=GO_REF:0000019, GO:0045944=GO_REF:0000019, GO:0007275=PMID:1672471, GO:0005634=GO_REF:0000039, GO:0030901=GO_REF:0000019, GO:0030902=GO_REF:0000019} P19622 Homeobox protein engrailed-2 protein 20030904 {GO:0043565=IEA, GO:0003700=IEA, GO:0016020=IEA, GO:0048666=IEA, GO:0045944=IEA, GO:0007275=TAS, GO:0005634=IEA, GO:0030901=IEA, GO:0030902=IEA} hindbrain development, midbrain development, multicellular organismal development, neuron development, positive regulation of transcription from RNA polymerase II promoter membrane, nucleus sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity Human ENAH HPA UniProtKB {GO:0050852=Reactome:REACT_12526, GO:0001725=GO_REF:0000019, GO:0017124=GO_REF:0000019, GO:0030054=GO_REF:0000052, GO:0005886=GO_REF:0000052, GO:0050699=PMID:17686488, GO:0001843=GO_REF:0000019, GO:0045202=GO_REF:0000039, GO:0046907=GO_REF:0000002, GO:0003779=GO_REF:0000037, GO:0030175=GO_REF:0000039, GO:0030027=GO_REF:0000039, GO:0005829=Reactome:REACT_19293, GO:0005737=GO_REF:0000052, GO:0008154=GO_REF:0000019, GO:0007411=Reactome:REACT_18266, GO:0005925=GO_REF:0000052} Q8N8S7 Protein enabled homolog protein 20111111 {GO:0050852=TAS, GO:0001725=IEA, GO:0017124=IEA, GO:0030054=IDA, GO:0005886=IDA, GO:0050699=IPI, GO:0001843=IEA, GO:0045202=IEA, GO:0046907=IEA, GO:0003779=IEA, GO:0030175=IEA, GO:0030027=IEA, GO:0005829=TAS, GO:0005737=IDA, GO:0008154=IEA, GO:0007411=TAS, GO:0005925=IDA} T cell receptor signaling pathway, actin polymerization or depolymerization, axon guidance, intracellular transport, neural tube closure cell junction, cytoplasm, cytosol, filopodium, focal adhesion, lamellipodium, plasma membrane, stress fiber, synapse SH3 domain binding, WW domain binding, actin binding Human ENAM UniProtKB UniProtKB {GO:0030345=GO_REF:0000029, GO:0097186=GO_REF:0000019, GO:0005578=GO_REF:0000029, GO:0042476=GO_REF:0000029, GO:0030282=GO_REF:0000029} Q9NRM1 Enamelin protein 20030113 {GO:0030345=NAS, GO:0097186=IEA, GO:0005578=NAS, GO:0042476=NAS, GO:0030282=NAS} amelogenesis, bone mineralization, odontogenesis proteinaceous extracellular matrix structural constituent of tooth enamel Human ENC1 PINC UniProtKB {GO:0005515=PMID:19424503, GO:0017148=PMID:19424503, GO:0005737=PMID:19424503, GO:0016567=PMID:15983046, GO:0031463=PMID:15983046, GO:0007275=PMID:9566959, GO:0005634=PMID:9566959, GO:0003779=GO_REF:0000037, GO:0005856=GO_REF:0000039, GO:0016363=GO_REF:0000039, GO:0007399=PMID:9566959, GO:0010499=PMID:19424503} O14682 Ectoderm-neural cortex protein 1 protein 20030904 {GO:0005515=IPI, GO:0017148=IDA, GO:0005737=IDA, GO:0016567=IDA, GO:0031463=IDA, GO:0007275=TAS, GO:0005634=TAS, GO:0003779=IEA, GO:0005856=IEA, GO:0016363=IEA, GO:0007399=TAS, GO:0010499=IDA} multicellular organismal development, negative regulation of translation, nervous system development, proteasomal ubiquitin-independent protein catabolic process, protein ubiquitination Cul3-RING ubiquitin ligase complex, cytoplasm, cytoskeleton, nuclear matrix, nucleus actin binding, protein binding Human ENDOD1 UniProtKB UniProtKB {GO:0004519=GO_REF:0000037, GO:0005576=GO_REF:0000039, GO:0003676=GO_REF:0000002, GO:0046872=GO_REF:0000002} O94919 Endonuclease domain-containing 1 protein protein 20130413 {GO:0004519=IEA, GO:0005576=IEA, GO:0003676=IEA, GO:0046872=IEA} extracellular region endonuclease activity, metal ion binding, nucleic acid binding Human UniProtKB-SubCell:SL-0243 ENDOG UniProtKB UniProtKB {GO:0005739=GO_REF:0000039, GO:0043065=GO_REF:0000019, GO:0004519=GO_REF:0000037, GO:0006309=GO_REF:0000019, GO:0034612=GO_REF:0000019, GO:0003676=GO_REF:0000002, GO:0001701=GO_REF:0000019, GO:0046677=GO_REF:0000019, GO:0046872=GO_REF:0000037} Q14249 Endonuclease G, mitochondrial protein 20130413 {GO:0005739=IEA, GO:0043065=IEA, GO:0004519=IEA, GO:0006309=IEA, GO:0034612=IEA, GO:0003676=IEA, GO:0001701=IEA, GO:0046677=IEA, GO:0046872=IEA} apoptotic DNA fragmentation, in utero embryonic development, positive regulation of apoptotic process, response to antibiotic, response to tumor necrosis factor mitochondrion endonuclease activity, metal ion binding, nucleic acid binding Human UniProtKB-SubCell:SL-0173 ENDOV UniProtKB UniProtKB {GO:0000287=GO_REF:0000024, GO:0006281=GO_REF:0000024, GO:0004519=GO_REF:0000002, GO:0016888=GO_REF:0000024} Q8N8Q3 Endonuclease V protein 20110516 {GO:0000287=ISS, GO:0006281=ISS, GO:0004519=IEA, GO:0016888=ISS} DNA repair endodeoxyribonuclease activity, producing 5'-phosphomonoesters, endonuclease activity, magnesium ion binding Human UniProtKB:Q8C9A2 ENG HPA UniProtKB {GO:0005515=PMID:20856203, GO:0005634=GO_REF:0000052, GO:0048844=PMID:8194490, GO:0005539=PMID:3262645, GO:0072563=GO_REF:0000019, GO:0048845=PMID:8194490, GO:0005615=PMID:19004009, GO:0042803=GO_REF:0000019, GO:0005114=PMID:8294451, GO:0001947=PMID:8194490, GO:0031953=PMID:12015308, GO:0030513=PMID:17068149, GO:0070022=PMID:1326540, GO:0005737=GO_REF:0000052, GO:0048185=PMID:11382917, GO:0048745=PMID:8194490, GO:0007155=GO_REF:0000037, GO:0017015=PMID:15702480, GO:0022009=PMID:7894484, GO:0050431=PMID:1326540, GO:0001569=PMID:8194490, GO:0006355=PMID:15702480, GO:0003273=GO_REF:0000019, GO:0005730=GO_REF:0000052, GO:0010862=PMID:12015308, GO:0030509=PMID:11382917, GO:0005072=PMID:12015308, GO:0005534=PMID:3262645, GO:0034713=PMID:8294451, GO:0001300=GO_REF:0000019, GO:0001934=PMID:12015308, GO:0001570=PMID:7894484, GO:0009897=PMID:1537377, GO:0004888=PMID:18974388} P17813 Endoglin protein 20101115 {GO:0005515=IPI, GO:0005634=IDA, GO:0048844=ISS, GO:0005539=IDA, GO:0072563=IEA, GO:0048845=ISS, GO:0005615=IDA, GO:0042803=IEA, GO:0005114=ISS, GO:0001947=ISS, GO:0031953=IDA, GO:0030513=IDA, GO:0070022=IC, GO:0005737=IDA, GO:0048185=TAS, GO:0048745=ISS, GO:0007155=IEA, GO:0017015=IDA, GO:0022009=IMP, GO:0050431=IPI, GO:0001569=ISS, GO:0006355=IMP, GO:0003273=IEA, GO:0005730=IDA, GO:0010862=IDA, GO:0030509=TAS, GO:0005072=IDA, GO:0005534=IDA, GO:0034713=ISS, GO:0001300=IEA, GO:0001934=IDA, GO:0001570=IMP, GO:0009897=IDA, GO:0004888=NAS} BMP signaling pathway, artery morphogenesis, cell adhesion, cell migration involved in endocardial cushion formation, central nervous system vasculogenesis, chronological cell aging, heart looping, negative regulation of protein autophosphorylation, patterning of blood vessels, positive regulation of BMP signaling pathway, positive regulation of pathway-restricted SMAD protein phosphorylation, positive regulation of protein phosphorylation, regulation of transcription, DNA-dependent, regulation of transforming growth factor beta receptor signaling pathway, smooth muscle tissue development, vasculogenesis, venous blood vessel morphogenesis cytoplasm, endothelial microparticle, external side of plasma membrane, extracellular space, nucleolus, nucleus, transforming growth factor beta receptor homodimeric complex activin binding, galactose binding, glycosaminoglycan binding, protein binding, protein homodimerization activity, transforming growth factor beta binding, transforming growth factor beta receptor, cytoplasmic mediator activity, transmembrane signaling receptor activity, type I transforming growth factor beta receptor binding, type II transforming growth factor beta receptor binding Human ENGASE UniProtKB UniProtKB {GO:0005737=GO_REF:0000002, GO:0033925=GO_REF:0000003, GO:0005829=GO_REF:0000039} Q8NFI3 Cytosolic endo-beta-N-acetylglucosaminidase protein 20130413 {GO:0005737=IEA, GO:0033925=IEA, GO:0005829=IEA} cytoplasm, cytosol mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase activity Human UniProtKB-SubCell:SL-0091 ENKUR UniProtKB UniProtKB {GO:0005929=GO_REF:0000037, GO:0005516=GO_REF:0000037, GO:0017124=GO_REF:0000037} Q8TC29 Enkurin protein 20130413 {GO:0005929=IEA, GO:0005516=IEA, GO:0017124=IEA} cilium SH3 domain binding, calmodulin binding Human UniProtKB-KW:KW-0729 ENO1 BHF-UCL UniProtKB {GO:0005515=PMID:21274509, GO:0030308=PMID:10082554, GO:0003700=PMID:2005901, GO:0000287=GO_REF:0000002, GO:0005886=GO_REF:0000039, GO:0005975=Reactome:REACT_474, GO:0003714=PMID:2005901, GO:0006094=Reactome:REACT_1520, GO:0005634=PMID:10082554, GO:0044281=Reactome:REACT_111217, GO:0000122=PMID:2005901, GO:0009615=PMID:16548883, GO:0003677=GO_REF:0000037, GO:0031430=GO_REF:0000039, GO:0004634=GO_REF:0000003, GO:0006096=Reactome:REACT_1383, GO:0006351=GO_REF:0000037, GO:0005829=Reactome:REACT_2018, GO:0005737=GO_REF:0000054, GO:0006006=Reactome:REACT_723, GO:0000015=GO_REF:0000002, GO:0045892=PMID:10082554} P06733 Alpha-enolase protein 20110222 {GO:0005515=IPI, GO:0030308=IDA, GO:0003700=TAS, GO:0000287=IEA, GO:0005886=IEA, GO:0005975=TAS, GO:0003714=TAS, GO:0006094=TAS, GO:0005634=IC, GO:0044281=TAS, GO:0000122=TAS, GO:0009615=IEP, GO:0003677=IEA, GO:0031430=IEA, GO:0004634=IEA, GO:0006096=TAS, GO:0006351=IEA, GO:0005829=TAS, GO:0005737=IDA, GO:0006006=TAS, GO:0000015=IEA, GO:0045892=IDA} carbohydrate metabolic process, gluconeogenesis, glucose metabolic process, glycolysis, negative regulation of cell growth, negative regulation of transcription from RNA polymerase II promoter, negative regulation of transcription, DNA-dependent, response to virus, small molecule metabolic process, transcription, DNA-dependent M band, cytoplasm, cytosol, nucleus, phosphopyruvate hydratase complex, plasma membrane DNA binding, magnesium ion binding, phosphopyruvate hydratase activity, protein binding, sequence-specific DNA binding transcription factor activity, transcription corepressor activity Human UniProtKB:O75952-1 ENO2 Reactome UniProtKB {GO:0001917=GO_REF:0000019, GO:0000287=GO_REF:0000002, GO:0005886=GO_REF:0000039, GO:0005975=Reactome:REACT_474, GO:0006094=Reactome:REACT_1520, GO:0006006=Reactome:REACT_723, GO:0043204=GO_REF:0000019, GO:0044281=Reactome:REACT_111217, GO:0000015=GO_REF:0000002, GO:0006096=Reactome:REACT_1383, GO:0004634=GO_REF:0000003, GO:0005829=Reactome:REACT_2018} P09104 Gamma-enolase protein 20130213 {GO:0001917=IEA, GO:0000287=IEA, GO:0005886=IEA, GO:0005975=TAS, GO:0006094=TAS, GO:0006006=TAS, GO:0043204=IEA, GO:0044281=TAS, GO:0000015=IEA, GO:0006096=TAS, GO:0004634=IEA, GO:0005829=TAS} carbohydrate metabolic process, gluconeogenesis, glucose metabolic process, glycolysis, small molecule metabolic process cytosol, perikaryon, phosphopyruvate hydratase complex, photoreceptor inner segment, plasma membrane magnesium ion binding, phosphopyruvate hydratase activity Human ENO3 HPA UniProtKB {GO:0000287=GO_REF:0000002, GO:0046982=GO_REF:0000019, GO:0005975=Reactome:REACT_474, GO:0042493=GO_REF:0000019, GO:0007568=GO_REF:0000019, GO:0006094=Reactome:REACT_1520, GO:0044281=Reactome:REACT_111217, GO:0006096=Reactome:REACT_1383, GO:0004634=GO_REF:0000003, GO:0042803=GO_REF:0000019, GO:0005829=Reactome:REACT_2018, GO:0005737=GO_REF:0000052, GO:0016020=GO_REF:0000019, GO:0006006=Reactome:REACT_723, GO:0043403=GO_REF:0000019, GO:0000015=GO_REF:0000002} P13929 Beta-enolase protein 20080205 {GO:0000287=IEA, GO:0046982=IEA, GO:0005975=TAS, GO:0042493=IEA, GO:0007568=IEA, GO:0006094=TAS, GO:0044281=TAS, GO:0006096=TAS, GO:0004634=IEA, GO:0042803=IEA, GO:0005829=TAS, GO:0005737=IDA, GO:0016020=IEA, GO:0006006=TAS, GO:0043403=IEA, GO:0000015=IEA} aging, carbohydrate metabolic process, gluconeogenesis, glucose metabolic process, glycolysis, response to drug, skeletal muscle tissue regeneration, small molecule metabolic process cytoplasm, cytosol, membrane, phosphopyruvate hydratase complex magnesium ion binding, phosphopyruvate hydratase activity, protein heterodimerization activity, protein homodimerization activity Human ENOPH1 Reactome UniProtKB {GO:0008967=GO_REF:0000002, GO:0034641=Reactome:REACT_13, GO:0000096=Reactome:REACT_115639, GO:0000287=GO_REF:0000002, GO:0019509=Reactome:REACT_75881, GO:0006595=Reactome:REACT_14820, GO:0005634=GO_REF:0000039, GO:0044281=Reactome:REACT_111217, GO:0005575=GO_REF:0000015, GO:0005829=Reactome:REACT_75868, GO:0043874=Reactome:REACT_75868} Q9UHY7 Enolase-phosphatase E1 protein 20110330 {GO:0008967=IEA, GO:0034641=TAS, GO:0000096=TAS, GO:0000287=IEA, GO:0019509=TAS, GO:0006595=TAS, GO:0005634=IEA, GO:0044281=TAS, GO:0005575=ND, GO:0005829=TAS, GO:0043874=TAS} L-methionine salvage from methylthioadenosine, cellular nitrogen compound metabolic process, polyamine metabolic process, small molecule metabolic process, sulfur amino acid metabolic process cellular_component, cytosol, nucleus acireductone synthase activity, magnesium ion binding, phosphoglycolate phosphatase activity Human ENOSF1 UniProtKB UniProtKB {GO:0005739=GO_REF:0000039, GO:0003674=GO_REF:0000015, GO:0008150=GO_REF:0000015, GO:0005575=GO_REF:0000015, GO:0016853=GO_REF:0000037, GO:0009063=GO_REF:0000002, GO:0003824=GO_REF:0000002, GO:0046872=GO_REF:0000037} Q7L5Y1 Mitochondrial enolase superfamily member 1 protein 20090723 {GO:0005739=IEA, GO:0003674=ND, GO:0008150=ND, GO:0005575=ND, GO:0016853=IEA, GO:0009063=IEA, GO:0003824=IEA, GO:0046872=IEA} biological_process, cellular amino acid catabolic process cellular_component, mitochondrion catalytic activity, isomerase activity, metal ion binding, molecular_function Human ENOX1 HPA UniProtKB {GO:0005886=GO_REF:0000052, GO:0000166=GO_REF:0000002, GO:0016491=GO_REF:0000037, GO:0048511=GO_REF:0000037, GO:0022900=GO_REF:0000037, GO:0003676=GO_REF:0000002, GO:0005615=GO_REF:0000039} Q8TC92 Ecto-NOX disulfide-thiol exchanger 1 protein 20110516 {GO:0005886=IDA, GO:0000166=IEA, GO:0016491=IEA, GO:0048511=IEA, GO:0022900=IEA, GO:0003676=IEA, GO:0005615=IEA} electron transport chain, rhythmic process extracellular space, plasma membrane nucleic acid binding, nucleotide binding, oxidoreductase activity Human ENOX2 PINC UniProtKB {GO:0000166=GO_REF:0000002, GO:0015035=PMID:1888291, GO:0007624=PMID:12356293, GO:0016049=PMID:9932650, GO:0022900=GO_REF:0000037, GO:0003676=GO_REF:0000002, GO:0005615=GO_REF:0000039, GO:0009897=PMID:11488599, GO:0040008=GO_REF:0000037, GO:0005829=PMID:8150545, GO:0055114=PMID:11888291} Q16206 Ecto-NOX disulfide-thiol exchanger 2 protein 20030904 {GO:0000166=IEA, GO:0015035=IDA, GO:0007624=IDA, GO:0016049=NAS, GO:0022900=IEA, GO:0003676=IEA, GO:0005615=IEA, GO:0009897=IDA, GO:0040008=IEA, GO:0005829=TAS, GO:0055114=IDA} cell growth, electron transport chain, oxidation-reduction process, regulation of growth, ultradian rhythm cytosol, external side of plasma membrane, extracellular space nucleic acid binding, nucleotide binding, protein disulfide oxidoreductase activity Human ENPEP Reactome UniProtKB {GO:0005886=Reactome:REACT_147872, GO:0002003=Reactome:REACT_147707, GO:0008283=PMID:14998491, GO:0007267=PMID:8346219, GO:0045177=GO_REF:0000024, GO:0001525=GO_REF:0000024, GO:0031410=GO_REF:0000024, GO:0032835=GO_REF:0000024, GO:0005903=GO_REF:0000024, GO:0003081=PMID:19608358, GO:0016324=GO_REF:0000024, GO:0016477=PMID:14998491, GO:0005887=PMID:8244382, GO:0004177=PMID:8244382, GO:0006508=GO_REF:0000037, GO:0070006=PMID:8346219, GO:0002005=PMID:19608358, GO:0008270=GO_REF:0000002, GO:0044267=Reactome:REACT_17015, GO:0008237=Reactome:REACT_147872, GO:0009897=GO_REF:0000024} Q07075 Glutamyl aminopeptidase protein 20111129 {GO:0005886=TAS, GO:0002003=TAS, GO:0008283=IDA, GO:0007267=NAS, GO:0045177=ISS, GO:0001525=ISS, GO:0031410=ISS, GO:0032835=ISS, GO:0005903=ISS, GO:0003081=IDA, GO:0016324=ISS, GO:0016477=IDA, GO:0005887=NAS, GO:0004177=IDA, GO:0006508=IEA, GO:0070006=IDA, GO:0002005=NAS, GO:0008270=IEA, GO:0044267=TAS, GO:0008237=EXP, GO:0009897=ISS} angiogenesis, angiotensin catabolic process in blood, angiotensin maturation, cell migration, cell proliferation, cell-cell signaling, cellular protein metabolic process, glomerulus development, proteolysis, regulation of systemic arterial blood pressure by renin-angiotensin apical part of cell, apical plasma membrane, brush border, cytoplasmic vesicle, external side of plasma membrane, integral to plasma membrane, plasma membrane aminopeptidase activity, metalloaminopeptidase activity, metallopeptidase activity, zinc ion binding Human ENPP1 BHF-UCL UniProtKB {GO:0005515=PMID:11289049, GO:0030308=PMID:17849011, GO:0050427=PMID:7830796, GO:0005886=PMID:10513816, GO:0045599=PMID:17849011, GO:0005158=PMID:7830796, GO:0004551=PMID:12746903, GO:0006767=Reactome:REACT_11238, GO:0009143=PMID:10513816, GO:0006091=PMID:12746903, GO:0044281=Reactome:REACT_111217, GO:0006796=PMID:11159191, GO:0003824=GO_REF:0000002, GO:0005615=PMID:11159191, GO:0042803=PMID:7830796, GO:0046872=GO_REF:0000037, GO:0031953=PMID:11289049, GO:0016323=PMID:9553761, GO:0006771=Reactome:REACT_11070, GO:0030279=GO_REF:0000019, GO:0006955=GO_REF:0000002, GO:0030730=PMID:17849011, GO:0004528=GO_REF:0000003, GO:0046849=GO_REF:0000019, GO:0046325=PMID:17849011, GO:0005044=GO_REF:0000002, GO:0032869=PMID:17849011, GO:0030500=PMID:10513816, GO:0009986=PMID:10513816, GO:0046627=PMID:17849011, GO:0050656=PMID:7830796, GO:0003676=GO_REF:0000002, GO:0005524=PMID:7830796, GO:0031214=GO_REF:0000037, GO:0045719=PMID:11289049, GO:0030505=PMID:10513816, GO:0030643=PMID:11159191, GO:0006766=Reactome:REACT_11193, GO:0047429=PMID:11159191, GO:0030247=GO_REF:0000002, GO:0016021=GO_REF:0000037, GO:0035529=GO_REF:0000003} P22413 Ectonucleotide pyrophosphatase/phosphodiesterase family member 1 protein 20080219 {GO:0005515=IPI, GO:0030308=IDA, GO:0050427=IDA, GO:0005886=IDA, GO:0045599=IDA, GO:0005158=IDA, GO:0004551=IDA, GO:0006767=TAS, GO:0009143=IDA, GO:0006091=IDA, GO:0044281=TAS, GO:0006796=IDA, GO:0003824=IEA, GO:0005615=IDA, GO:0042803=IDA, GO:0046872=IEA, GO:0031953=IDA, GO:0016323=NAS, GO:0006771=TAS, GO:0030279=IEA, GO:0006955=IEA, GO:0030730=IDA, GO:0004528=IEA, GO:0046849=IEA, GO:0046325=IDA, GO:0005044=IEA, GO:0032869=IDA, GO:0030500=IC, GO:0009986=IDA, GO:0046627=IDA, GO:0050656=IC, GO:0003676=IEA, GO:0005524=IDA, GO:0031214=IEA, GO:0045719=IDA, GO:0030505=IDA, GO:0030643=IDA, GO:0006766=TAS, GO:0047429=IDA, GO:0030247=IEA, GO:0016021=IEA, GO:0035529=IEA} 3'-phosphoadenosine 5'-phosphosulfate metabolic process, biomineral tissue development, bone remodeling, cellular phosphate ion homeostasis, cellular response to insulin stimulus, generation of precursor metabolites and energy, immune response, inorganic diphosphate transport, negative regulation of cell growth, negative regulation of fat cell differentiation, negative regulation of glucose import, negative regulation of glycogen biosynthetic process, negative regulation of insulin receptor signaling pathway, negative regulation of ossification, negative regulation of protein autophosphorylation, nucleoside triphosphate catabolic process, phosphate-containing compound metabolic process, regulation of bone mineralization, riboflavin metabolic process, sequestering of triglyceride, small molecule metabolic process, vitamin metabolic process, water-soluble vitamin metabolic process basolateral plasma membrane, cell surface, extracellular space, integral to membrane, plasma membrane 3'-phosphoadenosine 5'-phosphosulfate binding, ATP binding, NADH pyrophosphatase activity, catalytic activity, insulin receptor binding, metal ion binding, nucleic acid binding, nucleoside-triphosphate diphosphatase activity, nucleotide diphosphatase activity, phosphodiesterase I activity, polysaccharide binding, protein binding, protein homodimerization activity, scavenger receptor activity Human ENPP2 PINC UniProtKB {GO:0030334=PMID:1733949, GO:0005886=PMID:8579579, GO:0005509=GO_REF:0000024, GO:0004551=PMID:8579579, GO:0006928=PMID:1733949, GO:0006796=PMID:8579579, GO:0003676=GO_REF:0000002, GO:0003824=GO_REF:0000002, GO:0005615=GO_REF:0000024, GO:0046872=GO_REF:0000002, GO:0006955=GO_REF:0000002, GO:0004528=PMID:7982964, GO:0007186=PMID:1733949, GO:0016787=PMID:7982964, GO:0006935=PMID:7982964, GO:0005887=PMID:1733949, GO:0004622=PMID:21240271, GO:0030247=GO_REF:0000002, GO:0047391=GO_REF:0000003, GO:0008270=GO_REF:0000024, GO:0034638=PMID:21240271, GO:0008134=PMID:8586446, GO:0005044=GO_REF:0000002} Q13822 Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 protein 20030904 {GO:0030334=IDA, GO:0005886=TAS, GO:0005509=ISS, GO:0004551=TAS, GO:0006928=TAS, GO:0006796=TAS, GO:0003676=IEA, GO:0003824=IEA, GO:0005615=ISS, GO:0046872=IEA, GO:0006955=IEA, GO:0004528=TAS, GO:0007186=TAS, GO:0016787=TAS, GO:0006935=NAS, GO:0005887=TAS, GO:0004622=IDA, GO:0030247=IEA, GO:0047391=IEA, GO:0008270=ISS, GO:0034638=IDA, GO:0008134=TAS, GO:0005044=IEA} G-protein coupled receptor signaling pathway, cellular component movement, chemotaxis, immune response, phosphate-containing compound metabolic process, phosphatidylcholine catabolic process, regulation of cell migration extracellular space, integral to plasma membrane, plasma membrane alkylglycerophosphoethanolamine phosphodiesterase activity, calcium ion binding, catalytic activity, hydrolase activity, lysophospholipase activity, metal ion binding, nucleic acid binding, nucleotide diphosphatase activity, phosphodiesterase I activity, polysaccharide binding, scavenger receptor activity, transcription factor binding, zinc ion binding Human ENPP3 BHF-UCL UniProtKB {GO:0048471=PMID:10513816, GO:0004551=PMID:9344668, GO:0005576=GO_REF:0000039, GO:0009143=PMID:10513816, GO:0006796=PMID:10513816, GO:0003824=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0046872=GO_REF:0000037, GO:0030505=PMID:10513816, GO:0006955=GO_REF:0000002, GO:0004528=GO_REF:0000003, GO:0047429=PMID:10513816, GO:0005887=PMID:9344668, GO:0030247=GO_REF:0000002, GO:0035529=GO_REF:0000003, GO:0005044=GO_REF:0000002} O14638 Ectonucleotide pyrophosphatase/phosphodiesterase family member 3 protein 20080225 {GO:0048471=IDA, GO:0004551=TAS, GO:0005576=IEA, GO:0009143=IDA, GO:0006796=IDA, GO:0003824=IEA, GO:0003676=IEA, GO:0046872=IEA, GO:0030505=IDA, GO:0006955=IEA, GO:0004528=IEA, GO:0047429=IDA, GO:0005887=TAS, GO:0030247=IEA, GO:0035529=IEA, GO:0005044=IEA} immune response, inorganic diphosphate transport, nucleoside triphosphate catabolic process, phosphate-containing compound metabolic process extracellular region, integral to plasma membrane, perinuclear region of cytoplasm NADH pyrophosphatase activity, catalytic activity, metal ion binding, nucleic acid binding, nucleoside-triphosphate diphosphatase activity, nucleotide diphosphatase activity, phosphodiesterase I activity, polysaccharide binding, scavenger receptor activity Human ENPP7 Reactome UniProtKB {GO:0006665=Reactome:REACT_19323, GO:0006684=PMID:12671034, GO:0008285=PMID:12671034, GO:0005794=PMID:12671034, GO:0005886=Reactome:REACT_115560, GO:0006687=Reactome:REACT_116105, GO:0004767=PMID:12671034, GO:0044281=Reactome:REACT_111217, GO:0003824=GO_REF:0000002, GO:0005902=PMID:12671034, GO:0016020=PMID:12885774, GO:0016021=GO_REF:0000037, GO:0008156=PMID:12671034} Q6UWV6 Ectonucleotide pyrophosphatase/phosphodiesterase family member 7 protein 20130301 {GO:0006665=TAS, GO:0006684=IDA, GO:0008285=IDA, GO:0005794=IDA, GO:0005886=TAS, GO:0006687=TAS, GO:0004767=IDA, GO:0044281=TAS, GO:0003824=IEA, GO:0005902=IDA, GO:0016020=NAS, GO:0016021=IEA, GO:0008156=IDA} glycosphingolipid metabolic process, negative regulation of DNA replication, negative regulation of cell proliferation, small molecule metabolic process, sphingolipid metabolic process, sphingomyelin metabolic process Golgi apparatus, integral to membrane, membrane, microvillus, plasma membrane catalytic activity, sphingomyelin phosphodiesterase activity Human ENSA Reactome UniProtKB {GO:0007584=PMID:9653196, GO:0004864=GO_REF:0000037, GO:0008601=GO_REF:0000024, GO:0005102=PMID:9653196, GO:0019212=GO_REF:0000024, GO:0009749=GO_REF:0000019, GO:0005737=GO_REF:0000039, GO:0007067=GO_REF:0000024, GO:0000088=Reactome:REACT_765, GO:0000086=GO_REF:0000024, GO:0000087=Reactome:REACT_910, GO:0006810=PMID:9653196, GO:0005654=Reactome:REACT_150207, GO:0000278=Reactome:REACT_152, GO:0008200=PMID:9653196, GO:0051721=GO_REF:0000024, GO:0051301=GO_REF:0000037} O43768 Alpha-endosulfine protein 20120306 {GO:0007584=TAS, GO:0004864=IEA, GO:0008601=ISS, GO:0005102=TAS, GO:0019212=ISS, GO:0009749=IEA, GO:0005737=IEA, GO:0007067=ISS, GO:0000088=TAS, GO:0000086=ISS, GO:0000087=TAS, GO:0006810=TAS, GO:0005654=TAS, GO:0000278=TAS, GO:0008200=TAS, GO:0051721=ISS, GO:0051301=IEA} G2/M transition of mitotic cell cycle, M phase of mitotic cell cycle, cell division, mitosis, mitotic cell cycle, mitotic prophase, response to glucose stimulus, response to nutrient, transport cytoplasm, nucleoplasm ion channel inhibitor activity, phosphatase inhibitor activity, protein phosphatase 2A binding, protein phosphatase inhibitor activity, protein phosphatase type 2A regulator activity, receptor binding Human ENTHD1 null null {} null null null null {} null null null ENTPD1 PINC UniProtKB {GO:0005886=PMID:8955160, GO:0016787=GO_REF:0000037, GO:0007596=PMID:8955160, GO:0005887=PMID:7930580, GO:0007155=PMID:7930580, GO:0005524=GO_REF:0000037} P49961 Ectonucleoside triphosphate diphosphohydrolase 1 protein 20030904 {GO:0005886=NAS, GO:0016787=IEA, GO:0007596=TAS, GO:0005887=TAS, GO:0007155=NAS, GO:0005524=IEA} blood coagulation, cell adhesion integral to plasma membrane, plasma membrane ATP binding, hydrolase activity Human ENTPD2 ENSEMBL UniProtKB {GO:0017111=GO_REF:0000019, GO:0017110=GO_REF:0000019, GO:0007186=GO_REF:0000019, GO:0009181=GO_REF:0000019, GO:0005605=GO_REF:0000019, GO:0030168=GO_REF:0000019, GO:0016021=GO_REF:0000037, GO:0005524=GO_REF:0000037} Q9Y5L3 Ectonucleoside triphosphate diphosphohydrolase 2 protein 20130413 {GO:0017111=IEA, GO:0017110=IEA, GO:0007186=IEA, GO:0009181=IEA, GO:0005605=IEA, GO:0030168=IEA, GO:0016021=IEA, GO:0005524=IEA} G-protein coupled receptor signaling pathway, platelet activation, purine ribonucleoside diphosphate catabolic process basal lamina, integral to membrane ATP binding, nucleoside-diphosphatase activity, nucleoside-triphosphatase activity Human Ensembl:ENSMUSP00000028328 ENTPD4 HPA UniProtKB {GO:0030173=PMID:9556635, GO:0005737=GO_REF:0000052, GO:0016787=GO_REF:0000038, GO:0045134=PMID:9556635, GO:0000421=GO_REF:0000039, GO:0031410=GO_REF:0000037, GO:0006256=PMID:9556635, GO:0043231=GO_REF:0000052} Q9Y227 Ectonucleoside triphosphate diphosphohydrolase 4 protein 20090616 {GO:0030173=IDA, GO:0005737=IDA, GO:0016787=IEA, GO:0045134=IDA, GO:0000421=IEA, GO:0031410=IEA, GO:0006256=IDA, GO:0043231=IDA} UDP catabolic process autophagic vacuole membrane, cytoplasm, cytoplasmic vesicle, integral to Golgi membrane, intracellular membrane-bounded organelle hydrolase activity, uridine-diphosphatase activity Human ENTPD5 UniProtKB UniProtKB {GO:0046034=GO_REF:0000024, GO:0004382=GO_REF:0000024, GO:0005783=GO_REF:0000024, GO:0008283=GO_REF:0000024, GO:0014066=GO_REF:0000024, GO:0006096=GO_REF:0000024, GO:0016787=GO_REF:0000002, GO:0045134=GO_REF:0000024, GO:0005789=GO_REF:0000039, GO:0016049=GO_REF:0000024, GO:0051084=GO_REF:0000024, GO:0006487=GO_REF:0000024, GO:0016021=GO_REF:0000037} O75356 Ectonucleoside triphosphate diphosphohydrolase 5 protein 20101217 {GO:0046034=ISS, GO:0004382=ISS, GO:0005783=ISS, GO:0008283=ISS, GO:0014066=ISS, GO:0006096=ISS, GO:0016787=IEA, GO:0045134=ISS, GO:0005789=IEA, GO:0016049=ISS, GO:0051084=ISS, GO:0006487=ISS, GO:0016021=IEA} 'de novo' posttranslational protein folding, ATP metabolic process, cell growth, cell proliferation, glycolysis, protein N-linked glycosylation, regulation of phosphatidylinositol 3-kinase cascade endoplasmic reticulum, endoplasmic reticulum membrane, integral to membrane guanosine-diphosphatase activity, hydrolase activity, uridine-diphosphatase activity Human UniProtKB:Q9WUZ9 ENTPD6 InterPro UniProtKB {GO:0051592=GO_REF:0000019, GO:0017111=GO_REF:0000019, GO:0000139=GO_REF:0000039, GO:0009986=GO_REF:0000019, GO:0005886=GO_REF:0000019, GO:0016787=GO_REF:0000002, GO:0045134=GO_REF:0000003, GO:0032026=GO_REF:0000019, GO:0008894=GO_REF:0000019, GO:0016021=GO_REF:0000037, GO:0005615=GO_REF:0000019} Q5QPJ7 Ectonucleoside triphosphate diphosphohydrolase 6 protein 20130413 {GO:0051592=IEA, GO:0017111=IEA, GO:0000139=IEA, GO:0009986=IEA, GO:0005886=IEA, GO:0016787=IEA, GO:0045134=IEA, GO:0032026=IEA, GO:0008894=IEA, GO:0016021=IEA, GO:0005615=IEA} response to calcium ion, response to magnesium ion Golgi membrane, cell surface, extracellular space, integral to membrane, plasma membrane guanosine-5'-triphosphate,3'-diphosphate diphosphatase activity, hydrolase activity, nucleoside-triphosphatase activity, uridine-diphosphatase activity Human InterPro:IPR000407 ENY2 UniProtKB UniProtKB {GO:0016578=PMID:18206972, GO:0030374=PMID:18206972, GO:0000124=PMID:18206972, GO:0003713=PMID:18206972, GO:0051028=GO_REF:0000037, GO:0045893=PMID:18206972, GO:0006351=GO_REF:0000037} Q9NPA8 Enhancer of yellow 2 transcription factor homolog protein 20090427 {GO:0016578=IDA, GO:0030374=IDA, GO:0000124=IDA, GO:0003713=IDA, GO:0051028=IEA, GO:0045893=IDA, GO:0006351=IEA} histone deubiquitination, mRNA transport, positive regulation of transcription, DNA-dependent, transcription, DNA-dependent SAGA complex ligand-dependent nuclear receptor transcription coactivator activity, transcription coactivator activity Human EOMES BHF-UCL UniProtKB {GO:0001191=GO_REF:0000024, GO:0003700=GO_REF:0000002, GO:0045597=GO_REF:0000019, GO:0005634=GO_REF:0000039, GO:0001714=GO_REF:0000019, GO:0021772=GO_REF:0000019, GO:0045944=PMID:20713518, GO:0002302=PMID:17566017, GO:0032609=GO_REF:0000019, GO:0021895=GO_REF:0000019, GO:0001102=GO_REF:0000024, GO:0001706=GO_REF:0000024, GO:0000977=GO_REF:0000019, GO:0001707=GO_REF:0000024, GO:0060706=GO_REF:0000024, GO:0000122=GO_REF:0000024, GO:0001829=GO_REF:0000019, GO:0060809=GO_REF:0000024, GO:0003677=GO_REF:0000024, GO:0006351=GO_REF:0000038, GO:0043565=PMID:20713518, GO:0007420=PMID:17353897, GO:0019827=GO_REF:0000019, GO:0045664=GO_REF:0000019, GO:0045893=GO_REF:0000024} O95936 Eomesodermin homolog protein 20121106 {GO:0001191=ISS, GO:0003700=IEA, GO:0045597=IEA, GO:0005634=IEA, GO:0001714=IEA, GO:0021772=IEA, GO:0045944=IDA, GO:0002302=IMP, GO:0032609=IEA, GO:0021895=IEA, GO:0001102=ISS, GO:0001706=ISS, GO:0000977=IEA, GO:0001707=ISS, GO:0060706=ISS, GO:0000122=ISS, GO:0001829=IEA, GO:0060809=ISS, GO:0003677=ISS, GO:0006351=IEA, GO:0043565=IDA, GO:0007420=IMP, GO:0019827=IEA, GO:0045664=IEA, GO:0045893=ISS} CD8-positive, alpha-beta T cell differentiation involved in immune response, brain development, cell differentiation involved in embryonic placenta development, cerebral cortex neuron differentiation, endoderm formation, endodermal cell fate specification, interferon-gamma production, mesoderm formation, mesodermal to mesenchymal transition involved in gastrulation, negative regulation of transcription from RNA polymerase II promoter, olfactory bulb development, positive regulation of cell differentiation, positive regulation of transcription from RNA polymerase II promoter, positive regulation of transcription, DNA-dependent, regulation of neuron differentiation, stem cell maintenance, transcription, DNA-dependent, trophectodermal cell differentiation nucleus DNA binding, RNA polymerase II activating transcription factor binding, RNA polymerase II regulatory region sequence-specific DNA binding, RNA polymerase II transcription factor binding transcription factor activity involved in negative regulation of transcription, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity Human UniProtKB:O54839 EP300 HPA UniProtKB {GO:0005515=PMID:22770219, GO:0043627=PMID:11581164, GO:0008013=PMID:12408825, GO:0001756=GO_REF:0000019, GO:0018076=PMID:12435739, GO:0050681=PMID:18487222, GO:0007507=GO_REF:0000019, GO:0004468=PMID:20019387, GO:0007219=Reactome:REACT_118859, GO:0000123=GO_REF:0000019, GO:0009887=GO_REF:0000019, GO:0001102=PMID:20018936, GO:0003713=PMID:18487222, GO:0060765=PMID:18487222, GO:0033554=Reactome:REACT_120956, GO:0000122=PMID:10733570, GO:0031490=GO_REF:0000019, GO:0043923=PMID:16687403, GO:0018393=PMID:17403783, GO:0042771=PMID:17403783, GO:0007049=GO_REF:0000037, GO:0007519=GO_REF:0000019, GO:0043967=PMID:16325578, GO:0045087=Reactome:REACT_6802, GO:0016407=PMID:12435739, GO:0008270=GO_REF:0000002, GO:0005654=Reactome:REACT_160309, GO:0008134=PMID:15261140, GO:0016746=PMID:17403783, GO:0030324=GO_REF:0000019, GO:0061418=Reactome:REACT_120815, GO:0005634=GO_REF:0000052, GO:0032092=GO_REF:0000019, GO:0002039=GO_REF:0000019, GO:0005737=GO_REF:0000052, GO:0051091=PMID:10518217, GO:0045944=PMID:12586840, GO:0033613=PMID:20590529, GO:0004402=PMID:12040021, GO:0001666=PMID:9887100, GO:0005667=GO_REF:0000019, GO:0006355=PMID:15261140, GO:0005730=GO_REF:0000052, GO:0006915=PMID:9194565, GO:0071456=Reactome:REACT_121311, GO:0003677=PMID:9194565, GO:0006351=GO_REF:0000037, GO:0007399=PMID:10205054, GO:0019048=GO_REF:0000037, GO:0003682=PMID:17641689} Q09472 Histone acetyltransferase p300 protein 20120912 {GO:0005515=IPI, GO:0043627=IDA, GO:0008013=IPI, GO:0001756=IEA, GO:0018076=IDA, GO:0050681=IPI, GO:0007507=IEA, GO:0004468=IDA, GO:0007219=TAS, GO:0000123=IEA, GO:0009887=IEA, GO:0001102=IPI, GO:0003713=IDA, GO:0060765=IDA, GO:0033554=TAS, GO:0000122=IDA, GO:0031490=IEA, GO:0043923=IDA, GO:0018393=IDA, GO:0042771=IDA, GO:0007049=IEA, GO:0007519=IEA, GO:0043967=IMP, GO:0045087=TAS, GO:0016407=IMP, GO:0008270=IEA, GO:0005654=TAS, GO:0008134=IPI, GO:0016746=IDA, GO:0030324=IEA, GO:0061418=TAS, GO:0005634=IDA, GO:0032092=IEA, GO:0002039=IEA, GO:0005737=IDA, GO:0051091=IDA, GO:0045944=IDA, GO:0033613=IPI, GO:0004402=IDA, GO:0001666=IDA, GO:0005667=IEA, GO:0006355=IDA, GO:0005730=IDA, GO:0006915=IMP, GO:0071456=TAS, GO:0003677=IDA, GO:0006351=IEA, GO:0007399=TAS, GO:0019048=IEA, GO:0003682=IMP} N-terminal peptidyl-lysine acetylation, Notch signaling pathway, apoptotic process, cell cycle, cellular response to hypoxia, cellular response to stress, heart development, histone H4 acetylation, innate immune response, internal peptidyl-lysine acetylation, intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator, lung development, negative regulation of transcription from RNA polymerase II promoter, nervous system development, organ morphogenesis, positive regulation by host of viral transcription, positive regulation of protein binding, positive regulation of sequence-specific DNA binding transcription factor activity, positive regulation of transcription from RNA polymerase II promoter, regulation of androgen receptor signaling pathway, regulation of transcription from RNA polymerase II promoter in response to hypoxia, regulation of transcription, DNA-dependent, response to estrogen stimulus, response to hypoxia, skeletal muscle tissue development, somitogenesis, transcription, DNA-dependent, virus-host interaction cytoplasm, histone acetyltransferase complex, nucleolus, nucleoplasm, nucleus, transcription factor complex DNA binding, RNA polymerase II activating transcription factor binding, acetyltransferase activity, activating transcription factor binding, androgen receptor binding, beta-catenin binding, chromatin DNA binding, chromatin binding, histone acetyltransferase activity, lysine N-acetyltransferase activity, p53 binding, protein binding, transcription coactivator activity, transcription factor binding, transferase activity, transferring acyl groups, zinc ion binding Human EP400 UniProtKB UniProtKB {GO:0016607=GO_REF:0000024, GO:0043967=PMID:14966270, GO:0043968=PMID:14966270, GO:0003682=GO_REF:0000002, GO:0035267=PMID:14966270, GO:0004386=GO_REF:0000037, GO:0005524=GO_REF:0000037, GO:0003677=GO_REF:0000037} Q96L91 E1A-binding protein p400 protein 20100920 {GO:0016607=ISS, GO:0043967=IDA, GO:0043968=IDA, GO:0003682=IEA, GO:0035267=IDA, GO:0004386=IEA, GO:0005524=IEA, GO:0003677=IEA} histone H2A acetylation, histone H4 acetylation NuA4 histone acetyltransferase complex, nuclear speck ATP binding, DNA binding, chromatin binding, helicase activity Human UniProtKB:Q8CHI8 EP400NL null null {} null null null null {} null null null EPAS1 BHF-UCL UniProtKB {GO:0005515=PMID:18000879, GO:0006366=PMID:9079689, GO:0030324=GO_REF:0000019, GO:0061418=Reactome:REACT_120815, GO:0005829=Reactome:REACT_120857, GO:0042415=GO_REF:0000019, GO:0005737=GO_REF:0000019, GO:0045944=PMID:9576906, GO:0043129=GO_REF:0000019, GO:0048469=GO_REF:0000019, GO:0004871=GO_REF:0000002, GO:0048625=GO_REF:0000024, GO:0035035=PMID:15261140, GO:0005667=PMID:9576906, GO:0001666=PMID:11782478, GO:0046982=PMID:9079689, GO:0071456=Reactome:REACT_121311, GO:0001892=GO_REF:0000019, GO:0033554=Reactome:REACT_120956, GO:0043619=GO_REF:0000019, GO:0001525=GO_REF:0000019, GO:0003677=PMID:9000051, GO:0043565=PMID:9079689, GO:0007165=PMID:9079689, GO:0001077=GO_REF:0000019, GO:0002027=GO_REF:0000019, GO:0001974=GO_REF:0000019, GO:0030218=GO_REF:0000019, GO:0005654=Reactome:REACT_121374, GO:0007005=GO_REF:0000019, GO:0007601=GO_REF:0000019, GO:0008134=PMID:9079689} Q99814 Endothelial PAS domain-containing protein 1 protein 20101221 {GO:0005515=IPI, GO:0006366=TAS, GO:0030324=IEA, GO:0061418=TAS, GO:0005829=TAS, GO:0042415=IEA, GO:0005737=IEA, GO:0045944=IGI, GO:0043129=IEA, GO:0048469=IEA, GO:0004871=IEA, GO:0048625=ISS, GO:0035035=IPI, GO:0005667=IPI, GO:0001666=IDA, GO:0046982=IPI, GO:0071456=TAS, GO:0001892=IEA, GO:0033554=TAS, GO:0043619=IEA, GO:0001525=IEA, GO:0003677=IGI, GO:0043565=IDA, GO:0007165=TAS, GO:0001077=IEA, GO:0002027=IEA, GO:0001974=IEA, GO:0030218=IEA, GO:0005654=TAS, GO:0007005=IEA, GO:0007601=IEA, GO:0008134=IPI} angiogenesis, blood vessel remodeling, cell maturation, cellular response to hypoxia, cellular response to stress, embryonic placenta development, erythrocyte differentiation, lung development, mitochondrion organization, myoblast fate commitment, norepinephrine metabolic process, positive regulation of transcription from RNA polymerase II promoter, regulation of heart rate, regulation of transcription from RNA polymerase II promoter in response to hypoxia, regulation of transcription from RNA polymerase II promoter in response to oxidative stress, response to hypoxia, signal transduction, surfactant homeostasis, transcription from RNA polymerase II promoter, visual perception cytoplasm, cytosol, nucleoplasm, transcription factor complex DNA binding, RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription, histone acetyltransferase binding, protein binding, protein heterodimerization activity, sequence-specific DNA binding, signal transducer activity, transcription factor binding Human UniProtKB:P97481 EPB41 HPA UniProtKB {GO:0005515=PMID:8922391, GO:0008091=PMID:6894932, GO:0005516=GO_REF:0000037, GO:0005794=GO_REF:0000052, GO:0030036=PMID:8434260, GO:0005886=GO_REF:0000052, GO:0008015=PMID:6894932, GO:0030507=PMID:3693401, GO:0003779=GO_REF:0000037, GO:0005634=GO_REF:0000052, GO:0014731=PMID:3693401, GO:0032092=PMID:3693401, GO:0043231=GO_REF:0000052, GO:0043234=PMID:16060676, GO:0005545=PMID:16669616, GO:0005198=GO_REF:0000002, GO:0030866=GO_REF:0000002, GO:0005200=PMID:6894932, GO:0030863=PMID:16254212, GO:0005856=GO_REF:0000002, GO:0019898=GO_REF:0000002} P11171 Protein 4.1 protein 20101115 {GO:0005515=IPI, GO:0008091=TAS, GO:0005516=IEA, GO:0005794=IDA, GO:0030036=NAS, GO:0005886=IDA, GO:0008015=TAS, GO:0030507=TAS, GO:0003779=IEA, GO:0005634=IDA, GO:0014731=TAS, GO:0032092=IDA, GO:0043231=IDA, GO:0043234=IDA, GO:0005545=IDA, GO:0005198=IEA, GO:0030866=IEA, GO:0005200=TAS, GO:0030863=IDA, GO:0005856=IEA, GO:0019898=IEA} actin cytoskeleton organization, blood circulation, cortical actin cytoskeleton organization, positive regulation of protein binding Golgi apparatus, cortical cytoskeleton, cytoskeleton, extrinsic to membrane, intracellular membrane-bounded organelle, nucleus, plasma membrane, protein complex, spectrin, spectrin-associated cytoskeleton 1-phosphatidylinositol binding, actin binding, calmodulin binding, protein binding, spectrin binding, structural constituent of cytoskeleton, structural molecule activity Human EPB41L1 Reactome UniProtKB {GO:0008092=GO_REF:0000002, GO:0005737=GO_REF:0000002, GO:0005886=Reactome:REACT_18393, GO:0030866=GO_REF:0000002, GO:0005198=GO_REF:0000002, GO:0007268=Reactome:REACT_13685, GO:0003779=GO_REF:0000037, GO:0005856=GO_REF:0000039, GO:0005829=Reactome:REACT_18393, GO:0019898=GO_REF:0000002} Q9H4G0 Band 4.1-like protein 1 protein 20130301 {GO:0008092=IEA, GO:0005737=IEA, GO:0005886=TAS, GO:0030866=IEA, GO:0005198=IEA, GO:0007268=TAS, GO:0003779=IEA, GO:0005856=IEA, GO:0005829=TAS, GO:0019898=IEA} cortical actin cytoskeleton organization, synaptic transmission cytoplasm, cytoskeleton, cytosol, extrinsic to membrane, plasma membrane actin binding, cytoskeletal protein binding, structural molecule activity Human EPB41L2 InterPro UniProtKB {GO:0008092=GO_REF:0000002, GO:0008091=PMID:9598318, GO:0030054=GO_REF:0000052, GO:0005886=GO_REF:0000052, GO:0005730=GO_REF:0000052, GO:0003779=GO_REF:0000002, GO:0005634=GO_REF:0000052, GO:0005737=GO_REF:0000002, GO:0008180=PMID:18850735, GO:0005198=GO_REF:0000002, GO:0030866=GO_REF:0000002, GO:0005856=GO_REF:0000002, GO:0042731=GO_REF:0000019, GO:0019898=GO_REF:0000002} Q6ZSX4 Band 4.1-like protein 2 protein 20130413 {GO:0008092=IEA, GO:0008091=TAS, GO:0030054=IDA, GO:0005886=IDA, GO:0005730=IDA, GO:0003779=IEA, GO:0005634=IDA, GO:0005737=IEA, GO:0008180=IDA, GO:0005198=IEA, GO:0030866=IEA, GO:0005856=IEA, GO:0042731=IEA, GO:0019898=IEA} cortical actin cytoskeleton organization cell junction, cytoplasm, cytoskeleton, extrinsic to membrane, nucleolus, nucleus, plasma membrane, signalosome, spectrin PH domain binding, actin binding, cytoskeletal protein binding, structural molecule activity Human InterPro:IPR007477 EPB41L3 BHF-UCL UniProtKB {GO:0005515=PMID:12234973, GO:0005886=PMID:9892180, GO:0030913=GO_REF:0000024, GO:0044224=GO_REF:0000024, GO:0033270=GO_REF:0000024, GO:0003779=GO_REF:0000037, GO:0008150=GO_REF:0000015, GO:0005737=GO_REF:0000037, GO:0005198=GO_REF:0000002, GO:0030866=GO_REF:0000002, GO:0005911=PMID:12234973, GO:0048812=GO_REF:0000024, GO:0043217=GO_REF:0000024, GO:0030673=GO_REF:0000024, GO:0005856=GO_REF:0000039, GO:0019898=GO_REF:0000002} Q9Y2J2 Band 4.1-like protein 3 protein 20130111 {GO:0005515=IPI, GO:0005886=NAS, GO:0030913=ISS, GO:0044224=ISS, GO:0033270=ISS, GO:0003779=IEA, GO:0008150=ND, GO:0005737=IEA, GO:0005198=IEA, GO:0030866=IEA, GO:0005911=IDA, GO:0048812=ISS, GO:0043217=ISS, GO:0030673=ISS, GO:0005856=IEA, GO:0019898=IEA} biological_process, cortical actin cytoskeleton organization, myelin maintenance, neuron projection morphogenesis, paranodal junction assembly axolemma, cell-cell junction, cytoplasm, cytoskeleton, extrinsic to membrane, juxtaparanode region of axon, paranode region of axon, plasma membrane actin binding, protein binding, structural molecule activity Human UniProtKB:Q9WV92 EPB41L4A UniProtKB UniProtKB {GO:0008092=GO_REF:0000002, GO:0003674=GO_REF:0000015, GO:0008150=GO_REF:0000015, GO:0005737=GO_REF:0000037, GO:0005575=GO_REF:0000015, GO:0005856=GO_REF:0000039, GO:0019898=GO_REF:0000002} Q9HCS5 Band 4.1-like protein 4A protein 20061026 {GO:0008092=IEA, GO:0003674=ND, GO:0008150=ND, GO:0005737=IEA, GO:0005575=ND, GO:0005856=IEA, GO:0019898=IEA} biological_process cellular_component, cytoplasm, cytoskeleton, extrinsic to membrane cytoskeletal protein binding, molecular_function Human EPB41L4B MGI UniProtKB {GO:0008092=GO_REF:0000002, GO:0005737=GO_REF:0000037, GO:0005200=PMID:10783258, GO:0045177=PMID:22006950, GO:0031032=PMID:22006950, GO:0005856=GO_REF:0000039, GO:0019898=GO_REF:0000002} Q9H329 Band 4.1-like protein 4B protein 20120406 {GO:0008092=IEA, GO:0005737=IEA, GO:0005200=TAS, GO:0045177=IDA, GO:0031032=IDA, GO:0005856=IEA, GO:0019898=IEA} actomyosin structure organization apical part of cell, cytoplasm, cytoskeleton, extrinsic to membrane cytoskeletal protein binding, structural constituent of cytoskeleton Human EPB41L5 UniProtKB UniProtKB {GO:0008092=GO_REF:0000002, GO:0032091=GO_REF:0000019, GO:0010718=GO_REF:0000019, GO:0071560=GO_REF:0000019, GO:0001839=GO_REF:0000019, GO:0031032=GO_REF:0000019, GO:0070986=GO_REF:0000019, GO:0001837=GO_REF:0000019, GO:0051894=GO_REF:0000019, GO:0032092=GO_REF:0000019, GO:0006931=GO_REF:0000019, GO:0005737=GO_REF:0000039, GO:0032525=GO_REF:0000019, GO:0007509=GO_REF:0000019, GO:0070201=GO_REF:0000019, GO:0005856=GO_REF:0000002, GO:0048319=GO_REF:0000019, GO:0003383=GO_REF:0000019, GO:0022408=GO_REF:0000019, GO:0048339=GO_REF:0000019, GO:0019904=GO_REF:0000019, GO:0032587=GO_REF:0000019, GO:0007398=GO_REF:0000019, GO:0001701=GO_REF:0000019, GO:0009826=GO_REF:0000019, GO:0010608=GO_REF:0000019, GO:0007492=GO_REF:0000019, GO:0048617=GO_REF:0000019, GO:0010634=GO_REF:0000019, GO:0005925=GO_REF:0000019, GO:0019898=GO_REF:0000002} Q9HCM4 Band 4.1-like protein 5 protein 20130413 {GO:0008092=IEA, GO:0032091=IEA, GO:0010718=IEA, GO:0071560=IEA, GO:0001839=IEA, GO:0031032=IEA, GO:0070986=IEA, GO:0001837=IEA, GO:0051894=IEA, GO:0032092=IEA, GO:0006931=IEA, GO:0005737=IEA, GO:0032525=IEA, GO:0007509=IEA, GO:0070201=IEA, GO:0005856=IEA, GO:0048319=IEA, GO:0003383=IEA, GO:0022408=IEA, GO:0048339=IEA, GO:0019904=IEA, GO:0032587=IEA, GO:0007398=IEA, GO:0001701=IEA, GO:0009826=IEA, GO:0010608=IEA, GO:0007492=IEA, GO:0048617=IEA, GO:0010634=IEA, GO:0005925=IEA, GO:0019898=IEA} actomyosin structure organization, apical constriction, axial mesoderm morphogenesis, cellular response to transforming growth factor beta stimulus, ectoderm development, embryonic foregut morphogenesis, endoderm development, epithelial to mesenchymal transition, in utero embryonic development, left/right axis specification, mesoderm migration involved in gastrulation, negative regulation of cell-cell adhesion, negative regulation of protein binding, neural plate morphogenesis, paraxial mesoderm development, positive regulation of epithelial cell migration, positive regulation of epithelial to mesenchymal transition, positive regulation of focal adhesion assembly, positive regulation of protein binding, posttranscriptional regulation of gene expression, regulation of establishment of protein localization, somite rostral/caudal axis specification, substrate-dependent cell migration, cell attachment to substrate, unidimensional cell growth cytoplasm, cytoskeleton, extrinsic to membrane, focal adhesion, ruffle membrane cytoskeletal protein binding, protein domain specific binding Human UniProtKB-SubCell:SL-0086 EPB42 IntAct UniProtKB {GO:0005515=PMID:12970870, GO:0020027=GO_REF:0000019, GO:0005886=GO_REF:0000039, GO:0008360=GO_REF:0000037, GO:0048536=GO_REF:0000019, GO:0055072=GO_REF:0000019, GO:0005524=PMID:8608138, GO:0000902=GO_REF:0000019, GO:0018149=GO_REF:0000002, GO:0043249=GO_REF:0000037, GO:0003810=GO_REF:0000002, GO:0005200=PMID:1350227, GO:0030863=GO_REF:0000019, GO:0005856=PMID:1350227} P16452 Erythrocyte membrane protein band 4.2 protein 20130415 {GO:0005515=IPI, GO:0020027=IEA, GO:0005886=IEA, GO:0008360=IEA, GO:0048536=IEA, GO:0055072=IEA, GO:0005524=TAS, GO:0000902=IEA, GO:0018149=IEA, GO:0043249=IEA, GO:0003810=IEA, GO:0005200=TAS, GO:0030863=IEA, GO:0005856=TAS} cell morphogenesis, erythrocyte maturation, hemoglobin metabolic process, iron ion homeostasis, peptide cross-linking, regulation of cell shape, spleen development cortical cytoskeleton, cytoskeleton, plasma membrane ATP binding, protein binding, protein-glutamine gamma-glutamyltransferase activity, structural constituent of cytoskeleton Human UniProtKB:P58062 EPB49 HPA UniProtKB {GO:0005737=GO_REF:0000052, GO:0016020=GO_REF:0000019, GO:0007010=PMID:7615546, GO:0030863=GO_REF:0000019, GO:0005634=GO_REF:0000052, GO:0003779=GO_REF:0000037, GO:0015629=PMID:8341682, GO:0051017=PMID:7615546, GO:0051693=GO_REF:0000037} Q08495 Dematin protein 20101115 {GO:0005737=IDA, GO:0016020=IEA, GO:0007010=TAS, GO:0030863=IEA, GO:0005634=IDA, GO:0003779=IEA, GO:0015629=TAS, GO:0051017=TAS, GO:0051693=IEA} actin filament bundle assembly, actin filament capping, cytoskeleton organization actin cytoskeleton, cortical cytoskeleton, cytoplasm, membrane, nucleus actin binding Human EPC1 MGI UniProtKB {GO:0031965=PMID:10976108, GO:0005634=PMID:17192267, GO:0000122=PMID:10976108, GO:0006351=PMID:10976108, GO:0032777=PMID:14966270, GO:0043967=PMID:14966270, GO:0045944=PMID:10976108, GO:0045814=PMID:10976108, GO:0043968=PMID:14966270, GO:0035267=PMID:14966270, GO:0005654=PMID:10976108, GO:0045893=PMID:10976108, GO:0045892=PMID:10976108, GO:0040008=GO_REF:0000037, GO:0004402=PMID:14966270} Q9H2F5 Enhancer of polycomb homolog 1 protein 20070611 {GO:0031965=IDA, GO:0005634=IDA, GO:0000122=IDA, GO:0006351=TAS, GO:0032777=IDA, GO:0043967=IDA, GO:0045944=IDA, GO:0045814=IDA, GO:0043968=IDA, GO:0035267=IDA, GO:0005654=IDA, GO:0045893=TAS, GO:0045892=IDA, GO:0040008=IEA, GO:0004402=IDA} histone H2A acetylation, histone H4 acetylation, negative regulation of gene expression, epigenetic, negative regulation of transcription from RNA polymerase II promoter, negative regulation of transcription, DNA-dependent, positive regulation of transcription from RNA polymerase II promoter, positive regulation of transcription, DNA-dependent, regulation of growth, transcription, DNA-dependent NuA4 histone acetyltransferase complex, Piccolo NuA4 histone acetyltransferase complex, nuclear membrane, nucleoplasm, nucleus histone acetyltransferase activity Human EPC2 UniProtKB UniProtKB {GO:0006355=GO_REF:0000037, GO:0006281=GO_REF:0000037, GO:0032777=GO_REF:0000002, GO:0006351=GO_REF:0000037, GO:0016568=GO_REF:0000037} Q52LR7 Enhancer of polycomb homolog 2 protein 20130413 {GO:0006355=IEA, GO:0006281=IEA, GO:0032777=IEA, GO:0006351=IEA, GO:0016568=IEA} DNA repair, chromatin modification, regulation of transcription, DNA-dependent, transcription, DNA-dependent Piccolo NuA4 histone acetyltransferase complex Human UniProtKB-KW:KW-0156 EPCAM MGI UniProtKB {GO:0005515=PMID:16054130, GO:0016323=PMID:18025791, GO:0001657=GO_REF:0000019, GO:0016324=PMID:18025791, GO:0008284=PMID:15195135, GO:0005886=PMID:19785009, GO:0009986=GO_REF:0000019, GO:0005923=PMID:16054130, GO:0016021=GO_REF:0000019, GO:0016328=PMID:16054130} P16422 Epithelial cell adhesion molecule protein 20090324 {GO:0005515=IPI, GO:0016323=IDA, GO:0001657=IEA, GO:0016324=IDA, GO:0008284=IDA, GO:0005886=IDA, GO:0009986=IEA, GO:0005923=IDA, GO:0016021=IEA, GO:0016328=IDA} positive regulation of cell proliferation, ureteric bud development apical plasma membrane, basolateral plasma membrane, cell surface, integral to membrane, lateral plasma membrane, plasma membrane, tight junction protein binding Human EPDR1 UniProtKB UniProtKB {GO:0007160=GO_REF:0000002, GO:0005509=GO_REF:0000002, GO:0005576=GO_REF:0000039, GO:0005764=GO_REF:0000019} Q9UM22 Mammalian ependymin-related protein 1 protein 20130413 {GO:0007160=IEA, GO:0005509=IEA, GO:0005576=IEA, GO:0005764=IEA} cell-matrix adhesion extracellular region, lysosome calcium ion binding Human UniProtKB-SubCell:SL-0243 EPG5 UniProtKB UniProtKB {GO:0006914=GO_REF:0000037} Q9HCE0 Ectopic P granules protein 5 homolog protein 20130413 {GO:0006914=IEA} autophagy Human UniProtKB-KW:KW-0072 EPHA1 UniProtKB UniProtKB {GO:0008284=PMID:20043122, GO:0030336=PMID:19118217, GO:0030335=PMID:20043122, GO:0019901=PMID:19118217, GO:0001525=GO_REF:0000037, GO:0032862=PMID:19118217, GO:0005524=GO_REF:0000037, GO:0045766=PMID:20043122, GO:0005005=PMID:19118217, GO:0004672=PMID:12775584, GO:0046777=PMID:19118217, GO:0032314=PMID:19118217, GO:0005887=PMID:19118217, GO:0051496=GO_REF:0000024, GO:0034446=PMID:19118217, GO:0006469=PMID:19118217, GO:0001954=PMID:19118217, GO:0007166=PMID:19118217} P21709 Ephrin type-A receptor 1 protein 20110923 {GO:0008284=IMP, GO:0030336=IDA, GO:0030335=IMP, GO:0019901=IPI, GO:0001525=IEA, GO:0032862=IDA, GO:0005524=IEA, GO:0045766=IMP, GO:0005005=IDA, GO:0004672=IDA, GO:0046777=IDA, GO:0032314=IDA, GO:0005887=IDA, GO:0051496=ISS, GO:0034446=IDA, GO:0006469=IDA, GO:0001954=IDA, GO:0007166=IDA} activation of Rho GTPase activity, angiogenesis, cell surface receptor signaling pathway, negative regulation of cell migration, negative regulation of protein kinase activity, positive regulation of angiogenesis, positive regulation of cell migration, positive regulation of cell proliferation, positive regulation of cell-matrix adhesion, positive regulation of stress fiber assembly, protein autophosphorylation, regulation of Rac GTPase activity, substrate adhesion-dependent cell spreading integral to plasma membrane ATP binding, protein kinase activity, protein kinase binding, transmembrane-ephrin receptor activity Human UniProtKB:Q60750 EPHA2 IntAct UniProtKB {GO:0051898=PMID:19573808, GO:0005515=PMID:22939624, GO:0033628=PMID:10655584, GO:0005886=PMID:20861311, GO:0014028=GO_REF:0000019, GO:0010591=PMID:19573808, GO:0005003=GO_REF:0000002, GO:0046849=GO_REF:0000024, GO:0030182=GO_REF:0000019, GO:0070309=GO_REF:0000024, GO:0007155=GO_REF:0000037, GO:0070372=PMID:20861311, GO:0060035=GO_REF:0000019, GO:0031256=PMID:19573808, GO:0031258=GO_REF:0000039, GO:0048013=PMID:10655584, GO:0030316=GO_REF:0000024, GO:0045765=GO_REF:0000024, GO:0006915=PMID:18339848, GO:0007275=PMID:7918100, GO:0032587=GO_REF:0000039, GO:0001525=GO_REF:0000037, GO:0070848=PMID:19573808, GO:0032863=PMID:20679435, GO:0005524=GO_REF:0000037, GO:0001649=GO_REF:0000024, GO:0036342=GO_REF:0000019, GO:0043535=GO_REF:0000024, GO:0033598=GO_REF:0000024, GO:0001501=GO_REF:0000019, GO:0005887=PMID:10655584, GO:0060326=PMID:19573808, GO:0030216=PMID:20861311, GO:0043491=PMID:19573808, GO:0021915=GO_REF:0000019, GO:0004714=PMID:10655584, GO:0005925=PMID:10655584, GO:0001570=GO_REF:0000019, GO:0060444=GO_REF:0000024, GO:0048320=GO_REF:0000019, GO:0090004=PMID:20679435} P29317 Ephrin type-A receptor 2 protein 20130415 {GO:0051898=IDA, GO:0005515=IPI, GO:0033628=IDA, GO:0005886=IDA, GO:0014028=IEA, GO:0010591=IMP, GO:0005003=IEA, GO:0046849=ISS, GO:0030182=IEA, GO:0070309=ISS, GO:0007155=IEA, GO:0070372=IMP, GO:0060035=IEA, GO:0031256=IDA, GO:0031258=IEA, GO:0048013=IDA, GO:0030316=ISS, GO:0045765=ISS, GO:0006915=IDA, GO:0007275=TAS, GO:0032587=IEA, GO:0001525=IEA, GO:0070848=IMP, GO:0032863=IMP, GO:0005524=IEA, GO:0001649=ISS, GO:0036342=IEA, GO:0043535=ISS, GO:0033598=ISS, GO:0001501=IEA, GO:0005887=IDA, GO:0060326=IMP, GO:0030216=IMP, GO:0043491=IDA, GO:0021915=IEA, GO:0004714=IDA, GO:0005925=IDA, GO:0001570=IEA, GO:0060444=ISS, GO:0048320=IEA, GO:0090004=IMP} activation of Rac GTPase activity, angiogenesis, apoptotic process, axial mesoderm formation, bone remodeling, branching involved in mammary gland duct morphogenesis, cell adhesion, cell chemotaxis, ephrin receptor signaling pathway, keratinocyte differentiation, lens fiber cell morphogenesis, mammary gland epithelial cell proliferation, multicellular organismal development, negative regulation of protein kinase B signaling cascade, neural tube development, neuron differentiation, notochord cell development, notochord formation, osteoblast differentiation, osteoclast differentiation, positive regulation of establishment of protein localization to plasma membrane, post-anal tail morphogenesis, protein kinase B signaling cascade, regulation of ERK1 and ERK2 cascade, regulation of angiogenesis, regulation of blood vessel endothelial cell migration, regulation of cell adhesion mediated by integrin, regulation of lamellipodium assembly, response to growth factor stimulus, skeletal system development, vasculogenesis focal adhesion, integral to plasma membrane, lamellipodium membrane, leading edge membrane, plasma membrane, ruffle membrane ATP binding, ephrin receptor activity, protein binding, transmembrane receptor protein tyrosine kinase activity Human UniProtKB:P08238 EPHA3 BHF-UCL UniProtKB {GO:0005515=PMID:21135139, GO:0048013=PMID:11870224, GO:0071300=PMID:17910947, GO:0006915=GO_REF:0000024, GO:0010717=GO_REF:0000024, GO:0005576=GO_REF:0000039, GO:0005524=GO_REF:0000037, GO:0051893=PMID:11870224, GO:0070507=PMID:11870224, GO:0005004=PMID:11870224, GO:0005003=GO_REF:0000002, GO:0016477=GO_REF:0000024, GO:0005887=PMID:11870224, GO:0032956=PMID:11870224, GO:0010976=PMID:17910947, GO:0032319=PMID:11870224, GO:0007155=GO_REF:0000037, GO:0097156=GO_REF:0000024, GO:0097155=GO_REF:0000024, GO:0005769=PMID:21135139} P29320 Ephrin type-A receptor 3 protein 20110707 {GO:0005515=IPI, GO:0048013=IDA, GO:0071300=IMP, GO:0006915=ISS, GO:0010717=ISS, GO:0005576=IEA, GO:0005524=IEA, GO:0051893=IDA, GO:0070507=IDA, GO:0005004=IDA, GO:0005003=IEA, GO:0016477=ISS, GO:0005887=IDA, GO:0032956=IDA, GO:0010976=IMP, GO:0032319=IDA, GO:0007155=IEA, GO:0097156=ISS, GO:0097155=ISS, GO:0005769=IDA} apoptotic process, cell adhesion, cell migration, cellular response to retinoic acid, ephrin receptor signaling pathway, fasciculation of motor neuron axon, fasciculation of sensory neuron axon, positive regulation of neuron projection development, regulation of Rho GTPase activity, regulation of actin cytoskeleton organization, regulation of epithelial to mesenchymal transition, regulation of focal adhesion assembly, regulation of microtubule cytoskeleton organization early endosome, extracellular region, integral to plasma membrane ATP binding, GPI-linked ephrin receptor activity, ephrin receptor activity, protein binding Human EPHA4 UniProtKB UniProtKB {GO:0005515=PMID:12775584, GO:0030424=GO_REF:0000024, GO:0097161=PMID:12775584, GO:0030054=GO_REF:0000037, GO:0031594=GO_REF:0000019, GO:0008347=GO_REF:0000019, GO:0005783=GO_REF:0000019, GO:0005741=GO_REF:0000019, GO:0030175=GO_REF:0000019, GO:0030425=GO_REF:0000024, GO:0005005=GO_REF:0000024, GO:0005737=GO_REF:0000024, GO:0005004=GO_REF:0000024, GO:0005003=GO_REF:0000002, GO:0032314=GO_REF:0000024, GO:0048681=GO_REF:0000024, GO:0045211=GO_REF:0000037, GO:0007628=GO_REF:0000019, GO:0043204=GO_REF:0000019, GO:0043679=GO_REF:0000019, GO:0043507=GO_REF:0000019, GO:0007155=GO_REF:0000037, GO:0061001=GO_REF:0000024, GO:0097156=GO_REF:0000024, GO:0097155=GO_REF:0000024, GO:0032317=GO_REF:0000024, GO:0005794=GO_REF:0000019, GO:0009986=GO_REF:0000019, GO:0021957=GO_REF:0000024, GO:2001108=PMID:12775584, GO:0014069=GO_REF:0000039, GO:0044295=GO_REF:0000019, GO:0005524=GO_REF:0000037, GO:0048710=GO_REF:0000024, GO:0008045=GO_REF:0000024, GO:0004672=PMID:12775584, GO:0046875=GO_REF:0000019, GO:0005887=GO_REF:0000024, GO:0050775=GO_REF:0000019, GO:0031901=GO_REF:0000024, GO:0042731=PMID:12775584, GO:0050770=GO_REF:0000024} P54764 Ephrin type-A receptor 4 protein 20110819 {GO:0005515=IPI, GO:0030424=ISS, GO:0097161=IDA, GO:0030054=IEA, GO:0031594=IEA, GO:0008347=IEA, GO:0005783=IEA, GO:0005741=IEA, GO:0030175=IEA, GO:0030425=ISS, GO:0005005=ISS, GO:0005737=ISS, GO:0005004=ISS, GO:0005003=IEA, GO:0032314=ISS, GO:0048681=ISS, GO:0045211=IEA, GO:0007628=IEA, GO:0043204=IEA, GO:0043679=IEA, GO:0043507=IEA, GO:0007155=IEA, GO:0061001=ISS, GO:0097156=ISS, GO:0097155=ISS, GO:0032317=ISS, GO:0005794=IEA, GO:0009986=IEA, GO:0021957=ISS, GO:2001108=IDA, GO:0014069=IEA, GO:0044295=IEA, GO:0005524=IEA, GO:0048710=ISS, GO:0008045=ISS, GO:0004672=IDA, GO:0046875=IEA, GO:0005887=ISS, GO:0050775=IEA, GO:0031901=ISS, GO:0042731=IPI, GO:0050770=ISS} adult walking behavior, cell adhesion, corticospinal tract morphogenesis, fasciculation of motor neuron axon, fasciculation of sensory neuron axon, glial cell migration, motor neuron axon guidance, negative regulation of axon regeneration, positive regulation of JUN kinase activity, positive regulation of Rho guanyl-nucleotide exchange factor activity, positive regulation of dendrite morphogenesis, regulation of Rac GTPase activity, regulation of Rap GTPase activity, regulation of astrocyte differentiation, regulation of axonogenesis, regulation of dendritic spine morphogenesis Golgi apparatus, axon, axon terminus, axonal growth cone, cell junction, cell surface, cytoplasm, dendrite, early endosome membrane, endoplasmic reticulum, filopodium, integral to plasma membrane, mitochondrial outer membrane, neuromuscular junction, perikaryon, postsynaptic density, postsynaptic membrane ATP binding, DH domain binding, GPI-linked ephrin receptor activity, PH domain binding, ephrin receptor activity, ephrin receptor binding, protein binding, protein kinase activity, transmembrane-ephrin receptor activity Human UniProtKB:Q03137 EPHA5 UniProtKB UniProtKB {GO:0005791=PMID:10375373, GO:0030424=GO_REF:0000039, GO:0048471=PMID:10375373, GO:0051964=GO_REF:0000019, GO:0048013=GO_REF:0000024, GO:0005886=PMID:10375373, GO:0005524=GO_REF:0000037, GO:0030425=PMID:10375373, GO:0032793=GO_REF:0000024, GO:0021766=GO_REF:0000024, GO:0005005=PMID:7898931, GO:0005004=GO_REF:0000024, GO:0032314=GO_REF:0000024, GO:0005003=GO_REF:0000024, GO:0048666=PMID:10375373, GO:0007411=GO_REF:0000024, GO:0005887=GO_REF:0000002, GO:0032956=GO_REF:0000024, GO:0019933=GO_REF:0000024, GO:0043025=PMID:10375373, GO:0016021=GO_REF:0000038, GO:0061178=GO_REF:0000024, GO:0009897=PMID:10064801} P54756 Ephrin type-A receptor 5 protein 20110823 {GO:0005791=IDA, GO:0030424=IEA, GO:0048471=IDA, GO:0051964=IEA, GO:0048013=ISS, GO:0005886=IDA, GO:0005524=IEA, GO:0030425=IDA, GO:0032793=ISS, GO:0021766=ISS, GO:0005005=NAS, GO:0005004=ISS, GO:0032314=ISS, GO:0005003=ISS, GO:0048666=IEP, GO:0007411=ISS, GO:0005887=IEA, GO:0032956=ISS, GO:0019933=ISS, GO:0043025=IDA, GO:0016021=IEA, GO:0061178=ISS, GO:0009897=IDA} axon guidance, cAMP-mediated signaling, ephrin receptor signaling pathway, hippocampus development, negative regulation of synapse assembly, neuron development, positive regulation of CREB transcription factor activity, regulation of Rac GTPase activity, regulation of actin cytoskeleton organization, regulation of insulin secretion involved in cellular response to glucose stimulus axon, dendrite, external side of plasma membrane, integral to membrane, integral to plasma membrane, neuronal cell body, perinuclear region of cytoplasm, plasma membrane, rough endoplasmic reticulum ATP binding, GPI-linked ephrin receptor activity, ephrin receptor activity, transmembrane-ephrin receptor activity Human UniProtKB:Q60629 EPHA6 UniProtKB UniProtKB {GO:0003674=GO_REF:0000015, GO:0008150=GO_REF:0000015, GO:0005003=GO_REF:0000002, GO:0004672=GO_REF:0000002, GO:0005887=GO_REF:0000002, GO:0005575=GO_REF:0000015, GO:0016021=GO_REF:0000002, GO:0004713=GO_REF:0000038, GO:0005524=GO_REF:0000037} Q9UF33 Ephrin type-A receptor 6 protein 20110107 {GO:0003674=ND, GO:0008150=ND, GO:0005003=IEA, GO:0004672=IEA, GO:0005887=IEA, GO:0005575=ND, GO:0016021=IEA, GO:0004713=IEA, GO:0005524=IEA} biological_process cellular_component, integral to membrane, integral to plasma membrane ATP binding, ephrin receptor activity, molecular_function, protein kinase activity, protein tyrosine kinase activity Human EPHA7 IntAct UniProtKB {GO:0005515=PMID:22036564, GO:0031290=GO_REF:0000019, GO:0022407=GO_REF:0000024, GO:0031594=GO_REF:0000019, GO:0048013=PMID:17726105, GO:0050730=PMID:17726105, GO:0050919=GO_REF:0000024, GO:0005524=GO_REF:0000037, GO:0030425=GO_REF:0000019, GO:0031952=GO_REF:0000024, GO:0016310=GO_REF:0000024, GO:0045499=GO_REF:0000024, GO:0005004=GO_REF:0000024, GO:0043281=GO_REF:0000024, GO:0043525=GO_REF:0000024, GO:0046875=GO_REF:0000019, GO:0007420=GO_REF:0000024, GO:0005887=GO_REF:0000002, GO:0045211=GO_REF:0000019, GO:0043025=GO_REF:0000019, GO:0048755=GO_REF:0000024, GO:0004713=GO_REF:0000024, GO:0008046=GO_REF:0000024, GO:0070372=PMID:17726105} Q15375 Ephrin type-A receptor 7 protein 20130415 {GO:0005515=IPI, GO:0031290=IEA, GO:0022407=ISS, GO:0031594=IEA, GO:0048013=IDA, GO:0050730=IDA, GO:0050919=ISS, GO:0005524=IEA, GO:0030425=IEA, GO:0031952=ISS, GO:0016310=ISS, GO:0045499=ISS, GO:0005004=ISS, GO:0043281=ISS, GO:0043525=ISS, GO:0046875=IEA, GO:0007420=ISS, GO:0005887=IEA, GO:0045211=IEA, GO:0043025=IEA, GO:0048755=ISS, GO:0004713=ISS, GO:0008046=ISS, GO:0070372=IDA} brain development, branching morphogenesis of a nerve, ephrin receptor signaling pathway, negative chemotaxis, phosphorylation, positive regulation of neuron apoptotic process, regulation of ERK1 and ERK2 cascade, regulation of cell-cell adhesion, regulation of cysteine-type endopeptidase activity involved in apoptotic process, regulation of peptidyl-tyrosine phosphorylation, regulation of protein autophosphorylation, retinal ganglion cell axon guidance dendrite, integral to plasma membrane, neuromuscular junction, neuronal cell body, postsynaptic membrane ATP binding, GPI-linked ephrin receptor activity, axon guidance receptor activity, chemorepellent activity, ephrin receptor binding, protein binding, protein tyrosine kinase activity Human UniProtKB:P52793 EPHA8 UniProtKB UniProtKB {GO:0043005=GO_REF:0000024, GO:0033628=GO_REF:0000024, GO:0048013=GO_REF:0000024, GO:0006929=GO_REF:0000024, GO:0005524=GO_REF:0000037, GO:0030155=GO_REF:0000024, GO:0031175=GO_REF:0000024, GO:0016322=GO_REF:0000024, GO:0005004=GO_REF:0000024, GO:0046777=GO_REF:0000024, GO:0043552=GO_REF:0000024, GO:0005887=GO_REF:0000024, GO:0007411=GO_REF:0000024, GO:0031901=GO_REF:0000039, GO:0007155=GO_REF:0000037, GO:0043410=GO_REF:0000024} P29322 Ephrin type-A receptor 8 protein 20110830 {GO:0043005=ISS, GO:0033628=ISS, GO:0048013=ISS, GO:0006929=ISS, GO:0005524=IEA, GO:0030155=ISS, GO:0031175=ISS, GO:0016322=ISS, GO:0005004=ISS, GO:0046777=ISS, GO:0043552=ISS, GO:0005887=ISS, GO:0007411=ISS, GO:0031901=IEA, GO:0007155=IEA, GO:0043410=ISS} axon guidance, cell adhesion, ephrin receptor signaling pathway, neuron projection development, neuron remodeling, positive regulation of MAPK cascade, positive regulation of phosphatidylinositol 3-kinase activity, protein autophosphorylation, regulation of cell adhesion, regulation of cell adhesion mediated by integrin, substrate-dependent cell migration early endosome membrane, integral to plasma membrane, neuron projection ATP binding, GPI-linked ephrin receptor activity Human UniProtKB:O09127 EPHB1 IntAct UniProtKB {GO:0031290=GO_REF:0000024, GO:0005515=PMID:12223469, GO:0030424=GO_REF:0000019, GO:0030010=GO_REF:0000024, GO:0048593=GO_REF:0000019, GO:0030425=GO_REF:0000039, GO:0046328=PMID:9430661, GO:0061351=GO_REF:0000024, GO:0005005=PMID:18034775, GO:0005737=GO_REF:0000019, GO:0046777=PMID:18034775, GO:0005003=GO_REF:0000002, GO:0007411=GO_REF:0000024, GO:0060996=GO_REF:0000024, GO:0060997=GO_REF:0000024, GO:0070372=PMID:12925710, GO:0050965=GO_REF:0000024, GO:0022008=GO_REF:0000024, GO:0051965=GO_REF:0000024, GO:0048013=PMID:12925710, GO:0031589=PMID:9430661, GO:0021952=GO_REF:0000024, GO:0001525=PMID:9499402, GO:0005524=GO_REF:0000037, GO:0060326=PMID:12925710, GO:0005887=PMID:18034775, GO:0031901=PMID:18034775, GO:0045121=GO_REF:0000019, GO:0004713=GO_REF:0000019, GO:0016021=GO_REF:0000002, GO:0021631=GO_REF:0000019, GO:0008046=GO_REF:0000019} P54762 Ephrin type-B receptor 1 protein 20130415 {GO:0031290=ISS, GO:0005515=IPI, GO:0030424=IEA, GO:0030010=ISS, GO:0048593=IEA, GO:0030425=IEA, GO:0046328=IDA, GO:0061351=ISS, GO:0005005=IDA, GO:0005737=IEA, GO:0046777=IDA, GO:0005003=IEA, GO:0007411=ISS, GO:0060996=ISS, GO:0060997=ISS, GO:0070372=IDA, GO:0050965=ISS, GO:0022008=ISS, GO:0051965=ISS, GO:0048013=IDA, GO:0031589=IDA, GO:0021952=ISS, GO:0001525=IDA, GO:0005524=IEA, GO:0060326=IDA, GO:0005887=IDA, GO:0031901=IDA, GO:0045121=IEA, GO:0004713=IEA, GO:0016021=IEA, GO:0021631=IEA, GO:0008046=IEA} angiogenesis, axon guidance, camera-type eye morphogenesis, cell chemotaxis, cell-substrate adhesion, central nervous system projection neuron axonogenesis, dendritic spine development, dendritic spine morphogenesis, detection of temperature stimulus involved in sensory perception of pain, ephrin receptor signaling pathway, establishment of cell polarity, neural precursor cell proliferation, neurogenesis, optic nerve morphogenesis, positive regulation of synapse assembly, protein autophosphorylation, regulation of ERK1 and ERK2 cascade, regulation of JNK cascade, retinal ganglion cell axon guidance axon, cytoplasm, dendrite, early endosome membrane, integral to membrane, integral to plasma membrane, membrane raft ATP binding, axon guidance receptor activity, ephrin receptor activity, protein binding, protein tyrosine kinase activity, transmembrane-ephrin receptor activity Human UniProtKB:Q14451 EPHB2 InterPro UniProtKB {GO:0031290=GO_REF:0000019, GO:0030424=GO_REF:0000024, GO:0071679=GO_REF:0000024, GO:0001655=GO_REF:0000024, GO:0048593=GO_REF:0000019, GO:0030425=GO_REF:0000024, GO:0005005=GO_REF:0000024, GO:0005003=GO_REF:0000002, GO:0007413=GO_REF:0000024, GO:0007411=Reactome:REACT_18266, GO:0043025=GO_REF:0000019, GO:0060021=GO_REF:0000024, GO:0060996=GO_REF:0000024, GO:0007612=GO_REF:0000019, GO:0060997=GO_REF:0000024, GO:0051965=GO_REF:0000024, GO:0042472=GO_REF:0000024, GO:0048013=GO_REF:0000024, GO:0005102=GO_REF:0000019, GO:0021952=GO_REF:0000019, GO:0018108=GO_REF:0000024, GO:0001525=GO_REF:0000024, GO:0005524=GO_REF:0000002, GO:0007399=PMID:8589679, GO:0022038=GO_REF:0000024, GO:0016310=GO_REF:0000024, GO:0005887=GO_REF:0000024, GO:0050771=GO_REF:0000019, GO:0006468=GO_REF:0000029, GO:0016021=GO_REF:0000002, GO:0004713=GO_REF:0000024, GO:0021631=GO_REF:0000019, GO:0008046=GO_REF:0000019, GO:0050878=GO_REF:0000024, GO:0048170=GO_REF:0000019} Q6NVW1 EPHB2 protein protein 20130413 {GO:0031290=IEA, GO:0030424=ISS, GO:0071679=ISS, GO:0001655=ISS, GO:0048593=IEA, GO:0030425=ISS, GO:0005005=ISS, GO:0005003=IEA, GO:0007413=ISS, GO:0007411=TAS, GO:0043025=IEA, GO:0060021=ISS, GO:0060996=ISS, GO:0007612=IEA, GO:0060997=ISS, GO:0051965=ISS, GO:0042472=ISS, GO:0048013=ISS, GO:0005102=IEA, GO:0021952=IEA, GO:0018108=ISS, GO:0001525=ISS, GO:0005524=IEA, GO:0007399=TAS, GO:0022038=ISS, GO:0016310=ISS, GO:0005887=ISS, GO:0050771=IEA, GO:0006468=TAS, GO:0016021=IEA, GO:0004713=ISS, GO:0021631=IEA, GO:0008046=IEA, GO:0050878=ISS, GO:0048170=IEA} angiogenesis, axon guidance, axonal fasciculation, camera-type eye morphogenesis, central nervous system projection neuron axonogenesis, commissural neuron axon guidance, corpus callosum development, dendritic spine development, dendritic spine morphogenesis, ephrin receptor signaling pathway, inner ear morphogenesis, learning, negative regulation of axonogenesis, nervous system development, optic nerve morphogenesis, palate development, peptidyl-tyrosine phosphorylation, phosphorylation, positive regulation of long-term neuronal synaptic plasticity, positive regulation of synapse assembly, protein phosphorylation, regulation of body fluid levels, retinal ganglion cell axon guidance, urogenital system development axon, dendrite, integral to membrane, integral to plasma membrane, neuronal cell body ATP binding, axon guidance receptor activity, ephrin receptor activity, protein tyrosine kinase activity, receptor binding, transmembrane-ephrin receptor activity Human InterPro:IPR001426 EPHB3 UniProtKB UniProtKB {GO:0031290=GO_REF:0000019, GO:0001655=GO_REF:0000024, GO:0048538=GO_REF:0000024, GO:0030425=GO_REF:0000039, GO:0007413=GO_REF:0000024, GO:0005003=PMID:15536074, GO:0046777=PMID:15536074, GO:0032314=PMID:15536074, GO:0007411=GO_REF:0000024, GO:0034446=PMID:15536074, GO:0060021=GO_REF:0000024, GO:0060996=GO_REF:0000024, GO:0060997=GO_REF:0000024, GO:0051965=GO_REF:0000024, GO:0022407=PMID:8397371, GO:0048013=PMID:15536074, GO:0021952=GO_REF:0000019, GO:0001525=GO_REF:0000024, GO:0005524=GO_REF:0000037, GO:0048546=GO_REF:0000024, GO:0043088=PMID:15536074, GO:0022038=GO_REF:0000024, GO:0016477=PMID:15536074, GO:0005887=PMID:15536074, GO:0008046=GO_REF:0000019, GO:0050770=GO_REF:0000024} P54753 Ephrin type-B receptor 3 protein 20110906 {GO:0031290=IEA, GO:0001655=ISS, GO:0048538=ISS, GO:0030425=IEA, GO:0007413=ISS, GO:0005003=IDA, GO:0046777=IDA, GO:0032314=IDA, GO:0007411=ISS, GO:0034446=IDA, GO:0060021=ISS, GO:0060996=ISS, GO:0060997=ISS, GO:0051965=ISS, GO:0022407=IDA, GO:0048013=IDA, GO:0021952=IEA, GO:0001525=ISS, GO:0005524=IEA, GO:0048546=ISS, GO:0043088=IDA, GO:0022038=ISS, GO:0016477=IDA, GO:0005887=IDA, GO:0008046=IEA, GO:0050770=ISS} angiogenesis, axon guidance, axonal fasciculation, cell migration, central nervous system projection neuron axonogenesis, corpus callosum development, dendritic spine development, dendritic spine morphogenesis, digestive tract morphogenesis, ephrin receptor signaling pathway, palate development, positive regulation of synapse assembly, protein autophosphorylation, regulation of Cdc42 GTPase activity, regulation of Rac GTPase activity, regulation of axonogenesis, regulation of cell-cell adhesion, retinal ganglion cell axon guidance, substrate adhesion-dependent cell spreading, thymus development, urogenital system development dendrite, integral to plasma membrane ATP binding, axon guidance receptor activity, ephrin receptor activity Human UniProtKB:P54754 EPHB4 UniProtKB UniProtKB {GO:0005515=PMID:16867992, GO:0003007=GO_REF:0000024, GO:0005003=GO_REF:0000002, GO:0046777=PMID:8188704, GO:0048013=PMID:12734395, GO:0009986=PMID:12493773, GO:0005887=GO_REF:0000002, GO:0002042=PMID:12734395, GO:0001525=GO_REF:0000024, GO:0007155=PMID:12734395, GO:0004714=PMID:8188704, GO:0005524=GO_REF:0000038} Q96L35 EPH receptor B4, isoform CRA_b protein 20130413 {GO:0005515=IPI, GO:0003007=ISS, GO:0005003=IEA, GO:0046777=IDA, GO:0048013=IDA, GO:0009986=IDA, GO:0005887=IEA, GO:0002042=IDA, GO:0001525=ISS, GO:0007155=IDA, GO:0004714=IDA, GO:0005524=IEA} angiogenesis, cell adhesion, cell migration involved in sprouting angiogenesis, ephrin receptor signaling pathway, heart morphogenesis, protein autophosphorylation cell surface, integral to plasma membrane ATP binding, ephrin receptor activity, protein binding, transmembrane receptor protein tyrosine kinase activity Human UniProtKB-KW:KW-0067 EPHB6 PINC UniProtKB {GO:0005003=GO_REF:0000002, GO:0004672=GO_REF:0000002, GO:0048013=GO_REF:0000002, GO:0005887=GO_REF:0000002, GO:0004872=PMID:9207182, GO:0005576=GO_REF:0000039, GO:0016021=GO_REF:0000038, GO:0005524=GO_REF:0000037, GO:0035898=GO_REF:0000019, GO:0055074=GO_REF:0000019} O15197 Ephrin type-B receptor 6 protein 20030904 {GO:0005003=IEA, GO:0004672=IEA, GO:0048013=IEA, GO:0005887=IEA, GO:0004872=TAS, GO:0005576=IEA, GO:0016021=IEA, GO:0005524=IEA, GO:0035898=IEA, GO:0055074=IEA} calcium ion homeostasis, ephrin receptor signaling pathway, parathyroid hormone secretion extracellular region, integral to membrane, integral to plasma membrane ATP binding, ephrin receptor activity, protein kinase activity, receptor activity Human EPHX1 PINC UniProtKB {GO:0014070=GO_REF:0000019, GO:0033961=GO_REF:0000003, GO:0019439=GO_REF:0000037, GO:0006725=GO_REF:0000019, GO:0005789=GO_REF:0000039, GO:0009636=GO_REF:0000037, GO:0016021=GO_REF:0000037, GO:0004301=PMID:7516776} P07099 Epoxide hydrolase 1 protein 20030904 {GO:0014070=IEA, GO:0033961=IEA, GO:0019439=IEA, GO:0006725=IEA, GO:0005789=IEA, GO:0009636=IEA, GO:0016021=IEA, GO:0004301=TAS} aromatic compound catabolic process, cellular aromatic compound metabolic process, response to organic cyclic compound, response to toxic substance endoplasmic reticulum membrane, integral to membrane cis-stilbene-oxide hydrolase activity, epoxide hydrolase activity Human EPHX2 HPA UniProtKB {GO:0019369=Reactome:REACT_147851, GO:0090181=PMID:18974052, GO:0006805=PMID:10862610, GO:0017144=PMID:10862610, GO:0003869=PMID:12574508, GO:0044281=Reactome:REACT_111217, GO:0003824=GO_REF:0000002, GO:0042803=PMID:18513744, GO:0005829=Reactome:REACT_150274, GO:0016791=PMID:15196990, GO:0042577=PMID:12574510, GO:0005737=GO_REF:0000052, GO:0006954=PMID:10862610, GO:0045909=PMID:10862610, GO:0033885=GO_REF:0000003, GO:0005777=PMID:18513744, GO:0042632=PMID:18974052, GO:0000287=PMID:12574510, GO:0005794=GO_REF:0000052, GO:0019373=Reactome:REACT_150417, GO:0072593=PMID:10862610, GO:0005730=GO_REF:0000052, GO:0006874=PMID:10862610, GO:0005102=PMID:20178365, GO:0009636=PMID:10862610, GO:0010628=GO_REF:0000019, GO:0016787=GO_REF:0000002, GO:0046839=PMID:12574510, GO:0016311=PMID:12574508, GO:0046272=PMID:8342951, GO:0008217=PMID:10862610, GO:0005925=GO_REF:0000052, GO:0004301=Reactome:REACT_150274} P34913 Bifunctional epoxide hydrolase 2 protein 20101115 {GO:0019369=TAS, GO:0090181=IMP, GO:0006805=NAS, GO:0017144=NAS, GO:0003869=IDA, GO:0044281=TAS, GO:0003824=IEA, GO:0042803=IDA, GO:0005829=TAS, GO:0016791=IDA, GO:0042577=IDA, GO:0005737=IDA, GO:0006954=NAS, GO:0045909=NAS, GO:0033885=IEA, GO:0005777=IDA, GO:0042632=IDA, GO:0000287=IDA, GO:0005794=IDA, GO:0019373=TAS, GO:0072593=NAS, GO:0005730=IDA, GO:0006874=NAS, GO:0005102=IPI, GO:0009636=NAS, GO:0010628=IEA, GO:0016787=IEA, GO:0046839=IDA, GO:0016311=IDA, GO:0046272=IDA, GO:0008217=NAS, GO:0005925=IDA, GO:0004301=TAS} arachidonic acid metabolic process, cellular calcium ion homeostasis, cholesterol homeostasis, dephosphorylation, drug metabolic process, epoxygenase P450 pathway, inflammatory response, phospholipid dephosphorylation, positive regulation of gene expression, positive regulation of vasodilation, reactive oxygen species metabolic process, regulation of blood pressure, regulation of cholesterol metabolic process, response to toxic substance, small molecule metabolic process, stilbene catabolic process, xenobiotic metabolic process Golgi apparatus, cytoplasm, cytosol, focal adhesion, nucleolus, peroxisome 10-hydroxy-9-(phosphonooxy)octadecanoate phosphatase activity, 4-nitrophenylphosphatase activity, catalytic activity, epoxide hydrolase activity, hydrolase activity, lipid phosphatase activity, magnesium ion binding, phosphatase activity, protein homodimerization activity, receptor binding Human EPM2A GOC UniProtKB {GO:0005515=PMID:15930137, GO:0005886=GO_REF:0000039, GO:0005783=GO_REF:0000039, GO:0005977=PMID:9931343, GO:0005634=GO_REF:0000039, GO:0035335=PMID:9931343, GO:0007399=GO_REF:0000019, GO:0005829=PMID:12915448, GO:0005737=PMID:17908927, GO:0006470=PMID:11001928, GO:0030246=GO_REF:0000002, GO:0007610=GO_REF:0000019, GO:0004722=PMID:11001928, GO:0008138=GO_REF:0000002, GO:2001070=GO_REF:0000002, GO:0005844=PMID:11001928, GO:0004725=PMID:11001928} O95278 Laforin protein 20130413 {GO:0005515=IPI, GO:0005886=IEA, GO:0005783=IEA, GO:0005977=NAS, GO:0005634=IEA, GO:0035335=NAS, GO:0007399=IEA, GO:0005829=IDA, GO:0005737=IDA, GO:0006470=IDA, GO:0030246=IEA, GO:0007610=IEA, GO:0004722=TAS, GO:0008138=IEA, GO:2001070=IEA, GO:0005844=IDA, GO:0004725=IDA} behavior, glycogen metabolic process, nervous system development, peptidyl-tyrosine dephosphorylation, protein dephosphorylation cytoplasm, cytosol, endoplasmic reticulum, nucleus, plasma membrane, polysome carbohydrate binding, protein binding, protein serine/threonine phosphatase activity, protein tyrosine phosphatase activity, protein tyrosine/serine/threonine phosphatase activity, starch binding Human EPM2AIP1 UniProtKB UniProtKB {GO:0005783=GO_REF:0000039} Q7L775 EPM2A-interacting protein 1 protein 20130413 {GO:0005783=IEA} endoplasmic reticulum Human UniProtKB-SubCell:SL-0095 EPN1 Reactome UniProtKB {GO:0007565=GO_REF:0000019, GO:0005886=Reactome:REACT_12527, GO:0042059=Reactome:REACT_12484, GO:0005634=GO_REF:0000039, GO:0001701=GO_REF:0000019, GO:0006897=GO_REF:0000019, GO:0008289=GO_REF:0000037, GO:0005737=GO_REF:0000039, GO:0005905=GO_REF:0000039, GO:0007219=GO_REF:0000019, GO:0007173=Reactome:REACT_9417, GO:0048568=GO_REF:0000019, GO:0008134=GO_REF:0000019} Q9Y6I3 Epsin-1 protein 20130213 {GO:0007565=IEA, GO:0005886=TAS, GO:0042059=TAS, GO:0005634=IEA, GO:0001701=IEA, GO:0006897=IEA, GO:0008289=IEA, GO:0005737=IEA, GO:0005905=IEA, GO:0007219=IEA, GO:0007173=TAS, GO:0048568=IEA, GO:0008134=IEA} Notch signaling pathway, embryonic organ development, endocytosis, epidermal growth factor receptor signaling pathway, female pregnancy, in utero embryonic development, negative regulation of epidermal growth factor receptor signaling pathway coated pit, cytoplasm, nucleus, plasma membrane lipid binding, transcription factor binding Human EPN2 ENSEMBL UniProtKB {GO:0007219=GO_REF:0000019, GO:0048568=GO_REF:0000019, GO:0030128=GO_REF:0000002, GO:0001701=GO_REF:0000019, GO:0008289=GO_REF:0000037, GO:0006897=GO_REF:0000037} O95208 Epsin-2 protein 20130413 {GO:0007219=IEA, GO:0048568=IEA, GO:0030128=IEA, GO:0001701=IEA, GO:0008289=IEA, GO:0006897=IEA} Notch signaling pathway, embryonic organ development, endocytosis, in utero embryonic development clathrin coat of endocytic vesicle lipid binding Human Ensembl:ENSMUSP00000136950 EPN3 UniProtKB UniProtKB {GO:0048471=GO_REF:0000039, GO:0030136=GO_REF:0000039, GO:0005634=GO_REF:0000039, GO:0008289=GO_REF:0000037} Q9H201 Epsin-3 protein 20130413 {GO:0048471=IEA, GO:0030136=IEA, GO:0005634=IEA, GO:0008289=IEA} clathrin-coated vesicle, nucleus, perinuclear region of cytoplasm lipid binding Human UniProtKB-SubCell:SL-0198 EPO BHF-UCL UniProtKB {GO:0005515=PMID:9774108, GO:0042541=GO_REF:0000019, GO:0008284=PMID:9722506, GO:0043627=GO_REF:0000019, GO:0043499=PMID:14569084, GO:0009651=GO_REF:0000019, GO:0033189=GO_REF:0000019, GO:0008015=PMID:3838366, GO:0042523=PMID:9722506, GO:0061418=Reactome:REACT_120815, GO:0046579=PMID:9722506, GO:0005615=PMID:14569084, GO:0048678=GO_REF:0000019, GO:0032413=PMID:14569084, GO:0043249=GO_REF:0000037, GO:0018105=GO_REF:0000019, GO:0010766=PMID:14569084, GO:0051602=GO_REF:0000019, GO:0032496=GO_REF:0000019, GO:0033033=GO_REF:0000019, GO:0005128=GO_REF:0000002, GO:0070555=GO_REF:0000019, GO:0071474=PMID:14569084, GO:0043066=PMID:14569084, GO:0007566=GO_REF:0000019, GO:0045740=PMID:9722506, GO:0007568=GO_REF:0000019, GO:0071456=Reactome:REACT_121311, GO:0006915=GO_REF:0000019, GO:0005576=Reactome:REACT_121407, GO:0033554=Reactome:REACT_120956, GO:0030295=GO_REF:0000019, GO:0033574=GO_REF:0000019, GO:0007165=PMID:3838366, GO:0005179=GO_REF:0000037, GO:0045666=GO_REF:0000019, GO:0055093=GO_REF:0000019, GO:0045893=PMID:9722506} P01588 Erythropoietin protein 20080530 {GO:0005515=IPI, GO:0042541=IEA, GO:0008284=IDA, GO:0043627=IEA, GO:0043499=IDA, GO:0009651=IEA, GO:0033189=IEA, GO:0008015=NAS, GO:0042523=IDA, GO:0061418=TAS, GO:0046579=IDA, GO:0005615=IDA, GO:0048678=IEA, GO:0032413=IDA, GO:0043249=IEA, GO:0018105=IEA, GO:0010766=IDA, GO:0051602=IEA, GO:0032496=IEA, GO:0033033=IEA, GO:0005128=IEA, GO:0070555=IEA, GO:0071474=IDA, GO:0043066=IDA, GO:0007566=IEA, GO:0045740=IDA, GO:0007568=IEA, GO:0071456=TAS, GO:0006915=IEA, GO:0005576=TAS, GO:0033554=TAS, GO:0030295=IEA, GO:0033574=IEA, GO:0007165=NAS, GO:0005179=IEA, GO:0045666=IEA, GO:0055093=IEA, GO:0045893=IDA} aging, apoptotic process, blood circulation, cellular hyperosmotic response, cellular response to hypoxia, cellular response to stress, embryo implantation, erythrocyte maturation, hemoglobin biosynthetic process, negative regulation of apoptotic process, negative regulation of ion transmembrane transporter activity, negative regulation of myeloid cell apoptotic process, negative regulation of sodium ion transport, peptidyl-serine phosphorylation, positive regulation of DNA replication, positive regulation of Ras protein signal transduction, positive regulation of cell proliferation, positive regulation of neuron differentiation, positive regulation of transcription, DNA-dependent, positive regulation of tyrosine phosphorylation of Stat5 protein, regulation of transcription from RNA polymerase II promoter in response to hypoxia, response to axon injury, response to electrical stimulus, response to estrogen stimulus, response to hyperoxia, response to interleukin-1, response to lipopolysaccharide, response to salt stress, response to testosterone stimulus, response to vitamin A, signal transduction extracellular region, extracellular space erythropoietin receptor binding, eukaryotic cell surface binding, hormone activity, protein binding, protein kinase activator activity Human EPOR GOC UniProtKB {GO:0005515=PMID:15644415, GO:0038162=PMID:8506290, GO:0005576=GO_REF:0000039, GO:0009790=GO_REF:0000019, GO:0042802=PMID:21058338, GO:0007507=GO_REF:0000019, GO:0046697=GO_REF:0000019, GO:0007165=PMID:1668606, GO:0007420=GO_REF:0000019, GO:0005887=PMID:1848667, GO:0016021=GO_REF:0000002, GO:0004888=GO_REF:0000002, GO:0004900=PMID:2163696} P19235 Erythropoietin receptor protein 20130413 {GO:0005515=IPI, GO:0038162=TAS, GO:0005576=IEA, GO:0009790=IEA, GO:0042802=IPI, GO:0007507=IEA, GO:0046697=IEA, GO:0007165=NAS, GO:0007420=IEA, GO:0005887=TAS, GO:0016021=IEA, GO:0004888=IEA, GO:0004900=IDA} brain development, decidualization, embryo development, erythropoietin-mediated signaling pathway, heart development, signal transduction extracellular region, integral to membrane, integral to plasma membrane erythropoietin receptor activity, identical protein binding, protein binding, transmembrane signaling receptor activity Human EPPK1 UniProtKB UniProtKB {GO:0008150=GO_REF:0000015, GO:0005737=GO_REF:0000037, GO:0005198=GO_REF:0000029, GO:0005856=GO_REF:0000029} P58107 Epiplakin protein 20021104 {GO:0008150=ND, GO:0005737=IEA, GO:0005198=NAS, GO:0005856=NAS} biological_process cytoplasm, cytoskeleton structural molecule activity Human EPRS IntAct UniProtKB {GO:0005515=PMID:9556618, GO:0017148=PMID:23071094, GO:0010467=Reactome:REACT_71, GO:0035613=PMID:15479637, GO:0004818=Reactome:REACT_15345, GO:0004827=Reactome:REACT_15436, GO:0005524=GO_REF:0000037, GO:0005829=Reactome:REACT_15516, GO:0006418=Reactome:REACT_15482, GO:0005737=PMID:8188258, GO:0006424=GO_REF:0000002, GO:0006433=GO_REF:0000002, GO:0006461=PMID:8188258, GO:0071346=PMID:15479637, GO:0030529=PMID:15479637} P07814 Bifunctional glutamate/proline--tRNA ligase protein 20130415 {GO:0005515=IPI, GO:0017148=IDA, GO:0010467=TAS, GO:0035613=IDA, GO:0004818=TAS, GO:0004827=TAS, GO:0005524=IEA, GO:0005829=TAS, GO:0006418=TAS, GO:0005737=TAS, GO:0006424=IEA, GO:0006433=IEA, GO:0006461=TAS, GO:0071346=IDA, GO:0030529=IDA} cellular response to interferon-gamma, gene expression, glutamyl-tRNA aminoacylation, negative regulation of translation, prolyl-tRNA aminoacylation, protein complex assembly, tRNA aminoacylation for protein translation cytoplasm, cytosol, ribonucleoprotein complex ATP binding, RNA stem-loop binding, glutamate-tRNA ligase activity, proline-tRNA ligase activity, protein binding Human UniProtKB:P41252 EPS15 HPA UniProtKB {GO:0005515=PMID:21762413, GO:0017124=GO_REF:0000037, GO:0060170=GO_REF:0000019, GO:0005886=PMID:15465819, GO:0008283=PMID:8183552, GO:0030122=GO_REF:0000019, GO:0032456=PMID:12807910, GO:0005509=GO_REF:0000002, GO:0042059=Reactome:REACT_12484, GO:0015031=GO_REF:0000037, GO:0005829=Reactome:REACT_12527, GO:0043231=GO_REF:0000052, GO:0006897=GO_REF:0000037, GO:0016050=PMID:9762922, GO:0005737=GO_REF:0000052, GO:0005905=PMID:9762922, GO:0007173=Reactome:REACT_9417, GO:0031901=GO_REF:0000039, GO:0048268=PMID:12807910} P42566 Epidermal growth factor receptor substrate 15 protein 20081203 {GO:0005515=IPI, GO:0017124=IEA, GO:0060170=IEA, GO:0005886=IDA, GO:0008283=TAS, GO:0030122=IEA, GO:0032456=IC, GO:0005509=IEA, GO:0042059=TAS, GO:0015031=IEA, GO:0005829=TAS, GO:0043231=IDA, GO:0006897=IEA, GO:0016050=TAS, GO:0005737=IDA, GO:0005905=TAS, GO:0007173=TAS, GO:0031901=IEA, GO:0048268=IDA} cell proliferation, clathrin coat assembly, endocytic recycling, endocytosis, epidermal growth factor receptor signaling pathway, negative regulation of epidermal growth factor receptor signaling pathway, protein transport, vesicle organization AP-2 adaptor complex, cilium membrane, coated pit, cytoplasm, cytosol, early endosome membrane, intracellular membrane-bounded organelle, plasma membrane SH3 domain binding, calcium ion binding, protein binding Human EPS15L1 Reactome UniProtKB {GO:0005905=GO_REF:0000039, GO:0007173=Reactome:REACT_9417, GO:0005886=Reactome:REACT_12527, GO:0005509=GO_REF:0000002, GO:0042059=Reactome:REACT_12484, GO:0005634=GO_REF:0000039, GO:0006897=GO_REF:0000037} Q9UBC2 Epidermal growth factor receptor substrate 15-like 1 protein 20130213 {GO:0005905=IEA, GO:0007173=TAS, GO:0005886=TAS, GO:0005509=IEA, GO:0042059=TAS, GO:0005634=IEA, GO:0006897=IEA} endocytosis, epidermal growth factor receptor signaling pathway, negative regulation of epidermal growth factor receptor signaling pathway coated pit, nucleus, plasma membrane calcium ion binding Human EPS8 IntAct UniProtKB {GO:0005515=PMID:21988832, GO:0008344=GO_REF:0000019, GO:0008283=PMID:8084614, GO:0008360=GO_REF:0000024, GO:0017146=GO_REF:0000019, GO:0035415=GO_REF:0000024, GO:0030426=GO_REF:0000039, GO:0070358=GO_REF:0000024, GO:0051016=GO_REF:0000024, GO:0030832=GO_REF:0000024, GO:0007173=PMID:8084614, GO:0016301=GO_REF:0000038, GO:0051764=GO_REF:0000024, GO:0051017=GO_REF:0000024, GO:0005938=GO_REF:0000024, GO:0010458=GO_REF:0000024, GO:0031532=GO_REF:0000019, GO:0014069=GO_REF:0000019, GO:0032420=GO_REF:0000024, GO:0003779=GO_REF:0000024, GO:0032587=GO_REF:0000024, GO:0007165=PMID:8084614, GO:0048365=GO_REF:0000024, GO:0036336=GO_REF:0000024, GO:0016601=GO_REF:0000024, GO:0048149=GO_REF:0000019, GO:0005070=PMID:8084614} Q12929 Epidermal growth factor receptor kinase substrate 8 protein 20130415 {GO:0005515=IPI, GO:0008344=IEA, GO:0008283=TAS, GO:0008360=ISS, GO:0017146=IEA, GO:0035415=ISS, GO:0030426=IEA, GO:0070358=ISS, GO:0051016=ISS, GO:0030832=ISS, GO:0007173=TAS, GO:0016301=IEA, GO:0051764=ISS, GO:0051017=ISS, GO:0005938=ISS, GO:0010458=ISS, GO:0031532=IEA, GO:0014069=IEA, GO:0032420=ISS, GO:0003779=ISS, GO:0032587=ISS, GO:0007165=TAS, GO:0048365=ISS, GO:0036336=ISS, GO:0016601=ISS, GO:0048149=IEA, GO:0005070=TAS} Rac protein signal transduction, actin crosslink formation, actin cytoskeleton reorganization, actin filament bundle assembly, actin polymerization-dependent cell motility, adult locomotory behavior, barbed-end actin filament capping, behavioral response to ethanol, cell proliferation, dendritic cell migration, epidermal growth factor receptor signaling pathway, exit from mitosis, regulation of actin filament length, regulation of cell shape, regulation of mitotic prometaphase, signal transduction N-methyl-D-aspartate selective glutamate receptor complex, cell cortex, growth cone, postsynaptic density, ruffle membrane, stereocilium Rac GTPase binding, SH3/SH2 adaptor activity, actin binding, kinase activity, protein binding Human UniProtKB:P49419 EPS8L1 UniProtKB UniProtKB {GO:0003674=GO_REF:0000015, GO:0008150=GO_REF:0000015, GO:0005737=GO_REF:0000039, GO:0016301=GO_REF:0000038, GO:0005575=GO_REF:0000015} Q8TE68 Epidermal growth factor receptor kinase substrate 8-like protein 1 protein 20061106 {GO:0003674=ND, GO:0008150=ND, GO:0005737=IEA, GO:0016301=IEA, GO:0005575=ND} biological_process cellular_component, cytoplasm kinase activity, molecular_function Human EPS8L2 HPA UniProtKB {GO:0005737=GO_REF:0000052, GO:0005886=GO_REF:0000052} Q9H6S3 Epidermal growth factor receptor kinase substrate 8-like protein 2 protein 20111111 {GO:0005737=IDA, GO:0005886=IDA} cytoplasm, plasma membrane Human EPS8L3 UniProtKB UniProtKB {GO:0005737=GO_REF:0000039} Q8TE67 Epidermal growth factor receptor kinase substrate 8-like protein 3 protein 20130413 {GO:0005737=IEA} cytoplasm Human UniProtKB-SubCell:SL-0086 EPSTI1 null null {} null null null null {} null null null EPT1 Reactome UniProtKB {GO:0006646=Reactome:REACT_120919, GO:0016780=GO_REF:0000002, GO:0016020=GO_REF:0000002, GO:0004307=GO_REF:0000003, GO:0005789=Reactome:REACT_121214, GO:0044281=Reactome:REACT_111217, GO:0016021=GO_REF:0000037, GO:0008654=GO_REF:0000002, GO:0006644=Reactome:REACT_120870, GO:0046872=GO_REF:0000037, GO:0046474=Reactome:REACT_121401} Q9C0D9 Ethanolaminephosphotransferase 1 protein 20110819 {GO:0006646=TAS, GO:0016780=IEA, GO:0016020=IEA, GO:0004307=IEA, GO:0005789=TAS, GO:0044281=TAS, GO:0016021=IEA, GO:0008654=IEA, GO:0006644=TAS, GO:0046872=IEA, GO:0046474=TAS} glycerophospholipid biosynthetic process, phosphatidylethanolamine biosynthetic process, phospholipid biosynthetic process, phospholipid metabolic process, small molecule metabolic process endoplasmic reticulum membrane, integral to membrane, membrane ethanolaminephosphotransferase activity, metal ion binding, phosphotransferase activity, for other substituted phosphate groups Human EPX ENSEMBL UniProtKB {GO:0032753=GO_REF:0000019, GO:0004601=GO_REF:0000003, GO:0032693=GO_REF:0000019, GO:0032714=GO_REF:0000019, GO:0002215=GO_REF:0000019, GO:0042744=GO_REF:0000037, GO:0072677=GO_REF:0000019, GO:0046872=GO_REF:0000037, GO:0020037=GO_REF:0000002} P11678 Eosinophil peroxidase protein 20130413 {GO:0032753=IEA, GO:0004601=IEA, GO:0032693=IEA, GO:0032714=IEA, GO:0002215=IEA, GO:0042744=IEA, GO:0072677=IEA, GO:0046872=IEA, GO:0020037=IEA} defense response to nematode, eosinophil migration, hydrogen peroxide catabolic process, negative regulation of interleukin-10 production, negative regulation of interleukin-5 production, positive regulation of interleukin-4 production heme binding, metal ion binding, peroxidase activity Human Ensembl:ENSMUSP00000050497 ERAL1 UniProtKB UniProtKB {GO:0005759=PMID:20604745, GO:0003723=GO_REF:0000029, GO:0005743=GO_REF:0000039, GO:0019843=PMID:20604745, GO:0043024=PMID:20604745, GO:0005525=GO_REF:0000029, GO:0000028=PMID:20604745} O75616 GTPase Era, mitochondrial protein 20101217 {GO:0005759=IDA, GO:0003723=NAS, GO:0005743=IEA, GO:0019843=IDA, GO:0043024=IDA, GO:0005525=NAS, GO:0000028=IMP} ribosomal small subunit assembly mitochondrial inner membrane, mitochondrial matrix GTP binding, RNA binding, rRNA binding, ribosomal small subunit binding Human ERAP1 BHF-UCL UniProtKB {GO:0005515=PMID:18445477, GO:0005138=PMID:12748171, GO:0002474=Reactome:REACT_75820, GO:0005783=PMID:12748171, GO:0005576=PMID:11056387, GO:0001525=PMID:15691326, GO:0005151=PMID:15691326, GO:0045766=GO_REF:0000019, GO:0005829=PMID:10220586, GO:0009617=PMID:16034137, GO:0005737=GO_REF:0000019, GO:0019885=PMID:15691326, GO:0004177=PMID:12748171, GO:0045088=PMID:12748171, GO:0006508=GO_REF:0000002, GO:0005789=GO_REF:0000039, GO:0008217=PMID:15691326, GO:0008235=PMID:10220586, GO:0005788=Reactome:REACT_75798, GO:0045444=PMID:11056387, GO:0008270=PMID:10220586, GO:0016021=PMID:12748171, GO:0006509=PMID:12748171, GO:0008237=GO_REF:0000002} Q9NZ08 Endoplasmic reticulum aminopeptidase 1 protein 20081121 {GO:0005515=IPI, GO:0005138=IPI, GO:0002474=TAS, GO:0005783=NAS, GO:0005576=IDA, GO:0001525=TAS, GO:0005151=TAS, GO:0045766=IEA, GO:0005829=NAS, GO:0009617=IEP, GO:0005737=IEA, GO:0019885=TAS, GO:0004177=IDA, GO:0045088=NAS, GO:0006508=IEA, GO:0005789=IEA, GO:0008217=TAS, GO:0008235=IDA, GO:0005788=TAS, GO:0045444=NAS, GO:0008270=NAS, GO:0016021=NAS, GO:0006509=IDA, GO:0008237=IEA} angiogenesis, antigen processing and presentation of endogenous peptide antigen via MHC class I, antigen processing and presentation of peptide antigen via MHC class I, fat cell differentiation, membrane protein ectodomain proteolysis, positive regulation of angiogenesis, proteolysis, regulation of blood pressure, regulation of innate immune response, response to bacterium cytoplasm, cytosol, endoplasmic reticulum, endoplasmic reticulum lumen, endoplasmic reticulum membrane, extracellular region, integral to membrane aminopeptidase activity, interleukin-1, Type II receptor binding, interleukin-6 receptor binding, metalloexopeptidase activity, metallopeptidase activity, protein binding, zinc ion binding Human ERAP2 Reactome UniProtKB {GO:0002474=Reactome:REACT_75820, GO:0004177=PMID:12799365, GO:0019885=PMID:15691326, GO:0008217=PMID:12799365, GO:0005789=GO_REF:0000039, GO:0006508=GO_REF:0000037, GO:0005788=Reactome:REACT_75798, GO:0008270=PMID:12799365, GO:0016021=GO_REF:0000037, GO:0008237=PMID:12799365} Q6P179 Endoplasmic reticulum aminopeptidase 2 protein 20101029 {GO:0002474=TAS, GO:0004177=IDA, GO:0019885=TAS, GO:0008217=TAS, GO:0005789=IEA, GO:0006508=IEA, GO:0005788=TAS, GO:0008270=TAS, GO:0016021=IEA, GO:0008237=IDA} antigen processing and presentation of endogenous peptide antigen via MHC class I, antigen processing and presentation of peptide antigen via MHC class I, proteolysis, regulation of blood pressure endoplasmic reticulum lumen, endoplasmic reticulum membrane, integral to membrane aminopeptidase activity, metallopeptidase activity, zinc ion binding Human ERAS UniProtKB UniProtKB {GO:0005886=GO_REF:0000039, GO:0007264=GO_REF:0000002, GO:0003924=GO_REF:0000002, GO:0005525=GO_REF:0000037} Q7Z444 GTPase ERas protein 20130413 {GO:0005886=IEA, GO:0007264=IEA, GO:0003924=IEA, GO:0005525=IEA} small GTPase mediated signal transduction plasma membrane GTP binding, GTPase activity Human UniProtKB-SubCell:SL-0039 ERBB2 GOC UniProtKB {GO:0033088=GO_REF:0000019, GO:0005515=PMID:22939624, GO:0030307=PMID:21555369, GO:0030879=PMID:15504738, GO:0042802=PMID:21480528, GO:0005006=PMID:15504738, GO:0007507=PMID:15504738, GO:0046777=PMID:7556068, GO:0007173=Reactome:REACT_9417, GO:0007411=Reactome:REACT_18266, GO:0046983=PMID:12000754, GO:0070372=PMID:16314522, GO:0043125=PMID:9590694, GO:0023014=PMID:10851066, GO:0050679=PMID:10572067, GO:0046982=PMID:7556068, GO:0019903=PMID:15899872, GO:0014065=PMID:7556068, GO:0045785=PMID:7556068, GO:0043235=PMID:7556068, GO:0008045=GO_REF:0000019, GO:0008543=Reactome:REACT_9470, GO:0032321=GO_REF:0000024, GO:0045087=Reactome:REACT_6802, GO:0042060=PMID:12646923, GO:0007422=GO_REF:0000019, GO:0010008=PMID:16314522, GO:0004888=PMID:7514177, GO:0048471=GO_REF:0000039, GO:0005886=Reactome:REACT_147854, GO:0008283=PMID:10851066, GO:0005634=PMID:16314522, GO:0016323=PMID:12646923, GO:0005737=GO_REF:0000019, GO:0016324=GO_REF:0000019, GO:0019838=PMID:7514177, GO:0007528=GO_REF:0000019, GO:0045943=PMID:21555369, GO:0043406=PMID:10572067, GO:0045945=PMID:19372587, GO:0001042=PMID:21555369, GO:0048011=Reactome:REACT_11061, GO:0048015=Reactome:REACT_12464, GO:0042552=GO_REF:0000019, GO:0045765=PMID:15609325, GO:0032886=PMID:20937854, GO:0045727=PMID:21555369, GO:0008022=PMID:15520177, GO:0005524=GO_REF:0000037, GO:0006351=GO_REF:0000037, GO:0007399=PMID:15504738, GO:0007165=PMID:10572067, GO:0016020=GO_REF:0000002, GO:0001934=GO_REF:0000024, GO:0006468=PMID:10851066, GO:0016021=PMID:15609325, GO:0004713=PMID:7556068, GO:0004714=PMID:7514177, GO:0007169=PMID:7556068, GO:0004716=GO_REF:0000002, GO:0007166=PMID:9685399, GO:0007167=PMID:9590694} P04626 Receptor tyrosine-protein kinase erbB-2 protein 20130413 {GO:0033088=IEA, GO:0005515=IPI, GO:0030307=IMP, GO:0030879=TAS, GO:0042802=IPI, GO:0005006=NAS, GO:0007507=TAS, GO:0046777=IDA, GO:0007173=TAS, GO:0007411=TAS, GO:0046983=NAS, GO:0070372=IMP, GO:0043125=TAS, GO:0023014=TAS, GO:0050679=IDA, GO:0046982=IPI, GO:0019903=IPI, GO:0014065=IDA, GO:0045785=IDA, GO:0043235=TAS, GO:0008045=IEA, GO:0008543=TAS, GO:0032321=ISS, GO:0045087=TAS, GO:0042060=IDA, GO:0007422=IEA, GO:0010008=IDA, GO:0004888=IDA, GO:0048471=IEA, GO:0005886=TAS, GO:0008283=TAS, GO:0005634=IDA, GO:0016323=IDA, GO:0005737=IEA, GO:0016324=IEA, GO:0019838=IDA, GO:0007528=IEA, GO:0045943=IMP, GO:0043406=IDA, GO:0045945=IDA, GO:0001042=IDA, GO:0048011=TAS, GO:0048015=TAS, GO:0042552=IEA, GO:0045765=NAS, GO:0032886=IDA, GO:0045727=IMP, GO:0008022=IPI, GO:0005524=IEA, GO:0006351=IEA, GO:0007399=TAS, GO:0007165=IDA, GO:0016020=IEA, GO:0001934=ISS, GO:0006468=TAS, GO:0016021=NAS, GO:0004713=IDA, GO:0004714=IDA, GO:0007169=TAS, GO:0004716=IEA, GO:0007166=IDA, GO:0007167=TAS} axon guidance, cell proliferation, cell surface receptor signaling pathway, enzyme linked receptor protein signaling pathway, epidermal growth factor receptor signaling pathway, fibroblast growth factor receptor signaling pathway, heart development, innate immune response, mammary gland development, motor neuron axon guidance, myelination, negative regulation of immature T cell proliferation in thymus, nervous system development, neuromuscular junction development, neurotrophin TRK receptor signaling pathway, peripheral nervous system development, phosphatidylinositol 3-kinase cascade, phosphatidylinositol-mediated signaling, positive regulation of MAP kinase activity, positive regulation of Rho GTPase activity, positive regulation of cell adhesion, positive regulation of cell growth, positive regulation of epithelial cell proliferation, positive regulation of protein phosphorylation, positive regulation of transcription from RNA polymerase I promoter, positive regulation of transcription from RNA polymerase III promoter, positive regulation of translation, protein autophosphorylation, protein phosphorylation, regulation of ERK1 and ERK2 cascade, regulation of angiogenesis, regulation of microtubule-based process, signal transduction, signal transduction by phosphorylation, transcription, DNA-dependent, transmembrane receptor protein tyrosine kinase signaling pathway, wound healing apical plasma membrane, basolateral plasma membrane, cytoplasm, endosome membrane, integral to membrane, membrane, nucleus, perinuclear region of cytoplasm, plasma membrane, receptor complex ATP binding, ErbB-3 class receptor binding, RNA polymerase I core binding, epidermal growth factor-activated receptor activity, growth factor binding, identical protein binding, protein C-terminus binding, protein binding, protein dimerization activity, protein heterodimerization activity, protein phosphatase binding, protein tyrosine kinase activity, receptor signaling protein tyrosine kinase activity, transmembrane receptor protein tyrosine kinase activity, transmembrane signaling receptor activity Human ERBB2IP HPA UniProtKB {GO:0005515=PMID:16714539, GO:0030056=PMID:11375975, GO:0031965=GO_REF:0000039, GO:0005886=GO_REF:0000052, GO:0045104=PMID:11375975, GO:0005634=PMID:11375975, GO:0006605=GO_REF:0000019, GO:0045175=PMID:11375975, GO:0005604=PMID:10878805, GO:0045197=PMID:11375975, GO:0007165=PMID:10878805, GO:0005176=PMID:11375975, GO:0005737=PMID:11375975, GO:0007049=PMID:11375975, GO:0009925=PMID:11375975, GO:0005178=PMID:11375975, GO:0007173=PMID:11375975, GO:0007229=PMID:11375975, GO:0005200=PMID:11375975, GO:0016049=PMID:11375975, GO:0007155=PMID:11375975} Q96RT1 Protein LAP2 protein 20120912 {GO:0005515=IPI, GO:0030056=IDA, GO:0031965=IEA, GO:0005886=IDA, GO:0045104=NAS, GO:0005634=IDA, GO:0006605=IEA, GO:0045175=NAS, GO:0005604=TAS, GO:0045197=NAS, GO:0007165=TAS, GO:0005176=TAS, GO:0005737=IDA, GO:0007049=NAS, GO:0009925=NAS, GO:0005178=IPI, GO:0007173=TAS, GO:0007229=NAS, GO:0005200=NAS, GO:0016049=NAS, GO:0007155=NAS} basal protein localization, cell adhesion, cell cycle, cell growth, epidermal growth factor receptor signaling pathway, establishment or maintenance of epithelial cell apical/basal polarity, integrin-mediated signaling pathway, intermediate filament cytoskeleton organization, protein targeting, signal transduction basal plasma membrane, basement membrane, cytoplasm, hemidesmosome, nuclear membrane, nucleus, plasma membrane ErbB-2 class receptor binding, integrin binding, protein binding, structural constituent of cytoskeleton Human ERBB3 GOC UniProtKB {GO:0005515=PMID:22439932, GO:0005886=PMID:17701904, GO:0061098=PMID:7556068, GO:0051048=PMID:10559227, GO:0051402=PMID:17701904, GO:0005615=PMID:11389077, GO:0042803=PMID:11389077, GO:0007507=GO_REF:0000024, GO:0016323=PMID:12646923, GO:0014037=GO_REF:0000024, GO:0043524=GO_REF:0000024, GO:0016324=GO_REF:0000019, GO:0030296=PMID:7556068, GO:0007173=Reactome:REACT_9417, GO:0019838=PMID:7514177, GO:0042127=PMID:11389077, GO:0009968=PMID:11389077, GO:0048011=Reactome:REACT_11061, GO:0046982=PMID:7556068, GO:0003197=GO_REF:0000019, GO:0021545=GO_REF:0000024, GO:0048015=Reactome:REACT_12464, GO:0014068=PMID:17701904, GO:0016328=GO_REF:0000019, GO:0005524=GO_REF:0000037, GO:0014065=PMID:7556068, GO:0043235=PMID:7514177, GO:0007165=PMID:10572067, GO:0007162=PMID:7556068, GO:0004672=GO_REF:0000002, GO:0016020=GO_REF:0000002, GO:0005887=PMID:2687875, GO:0008543=Reactome:REACT_9470, GO:0045087=Reactome:REACT_6802, GO:0042060=PMID:12646923, GO:0007422=GO_REF:0000024, GO:0004713=PMID:7556068, GO:0004714=GO_REF:0000002, GO:0007169=PMID:7514177, GO:0004888=PMID:7514177} P21860 Receptor tyrosine-protein kinase erbB-3 protein 20130413 {GO:0005515=IPI, GO:0005886=TAS, GO:0061098=IDA, GO:0051048=IDA, GO:0051402=IMP, GO:0005615=IDA, GO:0042803=NAS, GO:0007507=ISS, GO:0016323=IDA, GO:0014037=ISS, GO:0043524=ISS, GO:0016324=IEA, GO:0030296=IDA, GO:0007173=TAS, GO:0019838=ISS, GO:0042127=IDA, GO:0009968=IDA, GO:0048011=TAS, GO:0046982=IPI, GO:0003197=IEA, GO:0021545=ISS, GO:0048015=TAS, GO:0014068=TAS, GO:0016328=IEA, GO:0005524=IEA, GO:0014065=IDA, GO:0043235=ISS, GO:0007165=IDA, GO:0007162=IDA, GO:0004672=IEA, GO:0016020=IEA, GO:0005887=TAS, GO:0008543=TAS, GO:0045087=TAS, GO:0042060=NAS, GO:0007422=ISS, GO:0004713=IDA, GO:0004714=IEA, GO:0007169=ISS, GO:0004888=ISS} Schwann cell differentiation, cranial nerve development, endocardial cushion development, epidermal growth factor receptor signaling pathway, fibroblast growth factor receptor signaling pathway, heart development, innate immune response, negative regulation of cell adhesion, negative regulation of neuron apoptotic process, negative regulation of secretion, negative regulation of signal transduction, neuron apoptotic process, neurotrophin TRK receptor signaling pathway, peripheral nervous system development, phosphatidylinositol 3-kinase cascade, phosphatidylinositol-mediated signaling, positive regulation of phosphatidylinositol 3-kinase cascade, positive regulation of protein tyrosine kinase activity, regulation of cell proliferation, signal transduction, transmembrane receptor protein tyrosine kinase signaling pathway, wound healing apical plasma membrane, basolateral plasma membrane, extracellular space, integral to plasma membrane, lateral plasma membrane, membrane, plasma membrane, receptor complex ATP binding, growth factor binding, protein binding, protein heterodimerization activity, protein homodimerization activity, protein kinase activity, protein tyrosine kinase activator activity, protein tyrosine kinase activity, transmembrane receptor protein tyrosine kinase activity, transmembrane signaling receptor activity Human ERBB4 HPA UniProtKB {GO:0005515=PMID:22939624, GO:0060045=GO_REF:0000024, GO:0021551=GO_REF:0000024, GO:0005154=PMID:8617750, GO:0044212=PMID:15534001, GO:0001755=GO_REF:0000024, GO:0042803=PMID:18334220, GO:0009880=GO_REF:0000024, GO:0007507=GO_REF:0000024, GO:0060644=GO_REF:0000024, GO:0046777=PMID:18334220, GO:0007173=Reactome:REACT_9417, GO:0005759=Reactome:REACT_115552, GO:0070374=PMID:10348342, GO:0030334=GO_REF:0000024, GO:0018108=PMID:18334220, GO:0045165=GO_REF:0000019, GO:0008543=Reactome:REACT_9470, GO:0045087=Reactome:REACT_6802, GO:0021889=GO_REF:0000024, GO:0005654=Reactome:REACT_116083, GO:0045893=PMID:15534001, GO:0008284=PMID:9135143, GO:0008285=PMID:17120616, GO:0005886=Reactome:REACT_147854, GO:0008283=PMID:8383326, GO:0042523=PMID:16837552, GO:0005634=GO_REF:0000052, GO:0005829=Reactome:REACT_116068, GO:0005739=PMID:16778220, GO:0016323=PMID:12646923, GO:0005737=GO_REF:0000052, GO:0061026=GO_REF:0000024, GO:2000366=PMID:15534001, GO:0048011=Reactome:REACT_11061, GO:0048015=Reactome:REACT_12464, GO:0005730=GO_REF:0000052, GO:0006915=PMID:16778220, GO:0005576=Reactome:REACT_115992, GO:0005524=GO_REF:0000037, GO:0006351=GO_REF:0000037, GO:0007399=GO_REF:0000024, GO:0007165=PMID:10572067, GO:0016477=PMID:9135143, GO:0007595=PMID:15534001, GO:0016020=GO_REF:0000002, GO:0001934=PMID:15534001, GO:0004713=PMID:18334220, GO:0016021=GO_REF:0000037, GO:0004714=PMID:18334220, GO:0007169=PMID:10353604, GO:0004716=GO_REF:0000002, GO:0060749=GO_REF:0000024} Q15303 Receptor tyrosine-protein kinase erbB-4 protein 20090616 {GO:0005515=IPI, GO:0060045=ISS, GO:0021551=ISS, GO:0005154=IPI, GO:0044212=IMP, GO:0001755=ISS, GO:0042803=IPI, GO:0009880=ISS, GO:0007507=ISS, GO:0060644=ISS, GO:0046777=IDA, GO:0007173=TAS, GO:0005759=TAS, GO:0070374=IMP, GO:0030334=ISS, GO:0018108=IDA, GO:0045165=IEA, GO:0008543=TAS, GO:0045087=TAS, GO:0021889=ISS, GO:0005654=TAS, GO:0045893=IMP, GO:0008284=IMP, GO:0008285=IMP, GO:0005886=TAS, GO:0008283=TAS, GO:0042523=IMP, GO:0005634=IDA, GO:0005829=TAS, GO:0005739=IDA, GO:0016323=IDA, GO:0005737=IDA, GO:0061026=ISS, GO:2000366=IMP, GO:0048011=TAS, GO:0048015=TAS, GO:0005730=IDA, GO:0006915=IMP, GO:0005576=TAS, GO:0005524=IEA, GO:0006351=IEA, GO:0007399=ISS, GO:0007165=IDA, GO:0016477=IDA, GO:0007595=IMP, GO:0016020=IEA, GO:0001934=TAS, GO:0004713=IDA, GO:0016021=IEA, GO:0004714=IDA, GO:0007169=IDA, GO:0004716=IEA, GO:0060749=ISS} apoptotic process, cardiac muscle tissue regeneration, cell fate commitment, cell migration, cell proliferation, central nervous system morphogenesis, embryonic pattern specification, epidermal growth factor receptor signaling pathway, fibroblast growth factor receptor signaling pathway, heart development, innate immune response, lactation, mammary gland alveolus development, mammary gland epithelial cell differentiation, negative regulation of cell proliferation, nervous system development, neural crest cell migration, neurotrophin TRK receptor signaling pathway, olfactory bulb interneuron differentiation, peptidyl-tyrosine phosphorylation, phosphatidylinositol-mediated signaling, positive regulation of ERK1 and ERK2 cascade, positive regulation of STAT protein import into nucleus, positive regulation of cardiac muscle cell proliferation, positive regulation of cell proliferation, positive regulation of protein phosphorylation, positive regulation of transcription, DNA-dependent, positive regulation of tyrosine phosphorylation of Stat5 protein, protein autophosphorylation, regulation of cell migration, signal transduction, transcription, DNA-dependent, transmembrane receptor protein tyrosine kinase signaling pathway basolateral plasma membrane, cytoplasm, cytosol, extracellular region, integral to membrane, membrane, mitochondrial matrix, mitochondrion, nucleolus, nucleoplasm, nucleus, plasma membrane ATP binding, epidermal growth factor receptor binding, protein binding, protein homodimerization activity, protein tyrosine kinase activity, receptor signaling protein tyrosine kinase activity, transcription regulatory region DNA binding, transmembrane receptor protein tyrosine kinase activity Human ERC1 UniProtKB UniProtKB {GO:0005515=PMID:12391317, GO:0017137=GO_REF:0000019, GO:0006355=PMID:15218148, GO:0007252=PMID:15218148, GO:0008385=PMID:15218148, GO:0007275=PMID:15218148, GO:0015031=GO_REF:0000037, GO:0043522=PMID:15218148, GO:0042734=PMID:12391317, GO:0005737=PMID:15218148, GO:0051092=PMID:15218148, GO:0000139=GO_REF:0000039, GO:0042147=GO_REF:0000019} Q8IUD2 ELKS/Rab6-interacting/CAST family member 1 protein 20051024 {GO:0005515=IPI, GO:0017137=IEA, GO:0006355=NAS, GO:0007252=IDA, GO:0008385=IDA, GO:0007275=NAS, GO:0015031=IEA, GO:0043522=NAS, GO:0042734=TAS, GO:0005737=TAS, GO:0051092=TAS, GO:0000139=IEA, GO:0042147=IEA} I-kappaB phosphorylation, multicellular organismal development, positive regulation of NF-kappaB transcription factor activity, protein transport, regulation of transcription, DNA-dependent, retrograde transport, endosome to Golgi Golgi membrane, IkappaB kinase complex, cytoplasm, presynaptic membrane Rab GTPase binding, leucine zipper domain binding, protein binding Human ERC2 IntAct UniProtKB {GO:0005515=PMID:20195357, GO:0042734=GO_REF:0000024, GO:0005737=GO_REF:0000039, GO:0030054=GO_REF:0000037, GO:0005856=GO_REF:0000039, GO:0030426=GO_REF:0000024} O15083 ERC protein 2 protein 20130415 {GO:0005515=IPI, GO:0042734=ISS, GO:0005737=IEA, GO:0030054=IEA, GO:0005856=IEA, GO:0030426=ISS} cell junction, cytoplasm, cytoskeleton, growth cone, presynaptic membrane protein binding Human UniProtKB:P10242 ERCC1 HPA UniProtKB {GO:0005515=PMID:8197175, GO:0051276=GO_REF:0000019, GO:0009650=GO_REF:0000019, GO:0010165=GO_REF:0000019, GO:0048477=GO_REF:0000019, GO:0008283=GO_REF:0000019, GO:0005634=GO_REF:0000052, GO:0010259=GO_REF:0000019, GO:0007283=GO_REF:0000019, GO:0007281=GO_REF:0000019, GO:0006302=GO_REF:0000019, GO:0000720=GO_REF:0000019, GO:0000109=PMID:3290851, GO:0005737=GO_REF:0000052, GO:0006295=PMID:7657672, GO:0003697=PMID:17720715, GO:0035264=GO_REF:0000019, GO:0006296=PMID:7657672, GO:0009744=GO_REF:0000019, GO:0048568=GO_REF:0000019, GO:0035166=GO_REF:0000019, GO:0006979=PMID:17614221, GO:0000784=PMID:14690602, GO:0043066=GO_REF:0000019, GO:0007584=GO_REF:0000019, GO:0045190=GO_REF:0000019, GO:0019904=PMID:17720715, GO:0005730=GO_REF:0000052, GO:0006310=PMID:11707424, GO:0008022=PMID:9722633, GO:0006312=PMID:8811092, GO:0003684=PMID:17720715, GO:0006949=GO_REF:0000019, GO:0006281=Reactome:REACT_216, GO:0004519=GO_REF:0000002, GO:0006283=Reactome:REACT_1628, GO:0043566=PMID:14734547, GO:0000014=PMID:7559382, GO:0005654=Reactome:REACT_2163, GO:0032205=PMID:17055345, GO:0001302=GO_REF:0000019, GO:0006289=Reactome:REACT_1826, GO:0000718=Reactome:REACT_311, GO:0008584=GO_REF:0000019} P07992 DNA excision repair protein ERCC-1 protein 20101115 {GO:0005515=IPI, GO:0051276=IEA, GO:0009650=IEA, GO:0010165=IEA, GO:0048477=IEA, GO:0008283=IEA, GO:0005634=IDA, GO:0010259=IEA, GO:0007283=IEA, GO:0007281=IEA, GO:0006302=IEA, GO:0000720=IEA, GO:0000109=IDA, GO:0005737=IDA, GO:0006295=IMP, GO:0003697=IDA, GO:0035264=IEA, GO:0006296=IMP, GO:0009744=IEA, GO:0048568=IEA, GO:0035166=IEA, GO:0006979=IMP, GO:0000784=IDA, GO:0043066=IEA, GO:0007584=IEA, GO:0045190=IEA, GO:0019904=IPI, GO:0005730=IDA, GO:0006310=IGI, GO:0008022=IPI, GO:0006312=IMP, GO:0003684=IDA, GO:0006949=IEA, GO:0006281=TAS, GO:0004519=IEA, GO:0006283=TAS, GO:0043566=IDA, GO:0000014=IDA, GO:0005654=TAS, GO:0032205=IMP, GO:0001302=IEA, GO:0006289=TAS, GO:0000718=TAS, GO:0008584=IEA} DNA recombination, DNA repair, UV protection, cell proliferation, chromosome organization, double-strand break repair, embryonic organ development, germ cell development, isotype switching, male gonad development, mitotic recombination, multicellular organism growth, multicellular organismal aging, negative regulation of apoptotic process, negative regulation of telomere maintenance, nucleotide-excision repair, nucleotide-excision repair, DNA damage removal, nucleotide-excision repair, DNA incision, 3'-to lesion, nucleotide-excision repair, DNA incision, 5'-to lesion, oogenesis, post-embryonic hemopoiesis, pyrimidine dimer repair by nucleotide-excision repair, replicative cell aging, response to X-ray, response to nutrient, response to oxidative stress, response to sucrose stimulus, spermatogenesis, syncytium formation, transcription-coupled nucleotide-excision repair cytoplasm, nuclear chromosome, telomeric region, nucleolus, nucleoplasm, nucleotide-excision repair complex, nucleus damaged DNA binding, endonuclease activity, protein C-terminus binding, protein binding, protein domain specific binding, single-stranded DNA binding, single-stranded DNA specific endodeoxyribonuclease activity, structure-specific DNA binding Human ERCC2 GOC UniProtKB {GO:0005515=PMID:11445587, GO:0010467=Reactome:REACT_71, GO:0006368=Reactome:REACT_2089, GO:0009650=PMID:2835663, GO:0006367=Reactome:REACT_1851, GO:0006366=Reactome:REACT_1366, GO:0000441=GO_REF:0000019, GO:0006363=Reactome:REACT_1074, GO:0006362=Reactome:REACT_2204, GO:0006361=Reactome:REACT_1974, GO:0006360=Reactome:REACT_1309, GO:0009791=GO_REF:0000019, GO:0030198=GO_REF:0000019, GO:0006979=PMID:17614221, GO:0008094=PMID:9852112, GO:0019907=PMID:8692842, GO:0007568=GO_REF:0000019, GO:0005819=PMID:20797633, GO:0006370=Reactome:REACT_1470, GO:0001701=GO_REF:0000019, GO:0006281=Reactome:REACT_216, GO:0006283=Reactome:REACT_1628, GO:0043388=GO_REF:0000019, GO:0043139=PMID:11445587, GO:0000075=PMID:17088560, GO:0005654=Reactome:REACT_2233, GO:0043588=GO_REF:0000019, GO:0006289=Reactome:REACT_1826, GO:0045893=PMID:8692842, GO:0022415=Reactome:REACT_6361, GO:0035315=PMID:11335038, GO:0021510=GO_REF:0000019, GO:0008283=GO_REF:0000019, GO:0005634=PMID:20797633, GO:0044281=Reactome:REACT_111217, GO:0030282=GO_REF:0000019, GO:0046872=GO_REF:0000037, GO:0005737=PMID:20797633, GO:0043249=GO_REF:0000019, GO:0004003=GO_REF:0000002, GO:0007059=PMID:20797633, GO:0035264=GO_REF:0000019, GO:0040016=GO_REF:0000019, GO:0045944=PMID:8692841, GO:0048820=GO_REF:0000019, GO:0016032=Reactome:REACT_6256, GO:0001666=GO_REF:0000019, GO:0043066=GO_REF:0000019, GO:0051539=GO_REF:0000037, GO:0006915=GO_REF:0000019, GO:0006917=PMID:8675009, GO:0060218=GO_REF:0000019, GO:0008022=PMID:10801852, GO:0032289=GO_REF:0000019, GO:0008353=PMID:9852112, GO:0003677=GO_REF:0000037, GO:0005524=GO_REF:0000037, GO:0050434=Reactome:REACT_6162, GO:0047485=PMID:8652557, GO:0004672=PMID:9852112, GO:0019048=GO_REF:0000037, GO:0006468=PMID:9852112, GO:0000718=Reactome:REACT_311, GO:0005675=PMID:9852112, GO:0033683=PMID:8692841, GO:0071817=PMID:20797633} P18074 TFIIH basal transcription factor complex helicase XPD subunit protein 20130413 {GO:0005515=IPI, GO:0010467=TAS, GO:0006368=TAS, GO:0009650=IGI, GO:0006367=TAS, GO:0006366=TAS, GO:0000441=IEA, GO:0006363=TAS, GO:0006362=TAS, GO:0006361=TAS, GO:0006360=TAS, GO:0009791=IEA, GO:0030198=IEA, GO:0006979=IMP, GO:0008094=IDA, GO:0019907=IDA, GO:0007568=IEA, GO:0005819=IDA, GO:0006370=TAS, GO:0001701=IEA, GO:0006281=TAS, GO:0006283=TAS, GO:0043388=IEA, GO:0043139=IDA, GO:0000075=IMP, GO:0005654=TAS, GO:0043588=IEA, GO:0006289=TAS, GO:0045893=IDA, GO:0022415=TAS, GO:0035315=IMP, GO:0021510=IEA, GO:0008283=IEA, GO:0005634=IDA, GO:0044281=TAS, GO:0030282=IEA, GO:0046872=IEA, GO:0005737=IDA, GO:0043249=IEA, GO:0004003=IEA, GO:0007059=IMP, GO:0035264=IEA, GO:0040016=IEA, GO:0045944=IDA, GO:0048820=IEA, GO:0016032=TAS, GO:0001666=IEA, GO:0043066=IEA, GO:0051539=IEA, GO:0006915=IEA, GO:0006917=IMP, GO:0060218=IEA, GO:0008022=IPI, GO:0032289=IEA, GO:0008353=IDA, GO:0003677=IEA, GO:0005524=IEA, GO:0050434=TAS, GO:0047485=IPI, GO:0004672=IDA, GO:0019048=IEA, GO:0006468=IDA, GO:0000718=TAS, GO:0005675=IDA, GO:0033683=IMP, GO:0071817=IDA} 7-methylguanosine mRNA capping, DNA repair, UV protection, aging, apoptotic process, bone mineralization, cell cycle checkpoint, cell proliferation, central nervous system myelin formation, chromosome segregation, embryonic cleavage, erythrocyte maturation, extracellular matrix organization, gene expression, hair cell differentiation, hair follicle maturation, hematopoietic stem cell differentiation, in utero embryonic development, induction of apoptosis, multicellular organism growth, negative regulation of apoptotic process, nucleotide-excision repair, nucleotide-excision repair, DNA damage removal, nucleotide-excision repair, DNA incision, positive regulation of DNA binding, positive regulation of transcription from RNA polymerase II promoter, positive regulation of transcription, DNA-dependent, positive regulation of viral transcription, post-embryonic development, protein phosphorylation, response to hypoxia, response to oxidative stress, skin development, small molecule metabolic process, spinal cord development, termination of RNA polymerase I transcription, transcription elongation from RNA polymerase I promoter, transcription elongation from RNA polymerase II promoter, transcription from RNA polymerase I promoter, transcription from RNA polymerase II promoter, transcription initiation from RNA polymerase I promoter, transcription initiation from RNA polymerase II promoter, transcription-coupled nucleotide-excision repair, viral reproduction, viral reproductive process, virus-host interaction MMXD complex, SSL2-core TFIIH complex, cyclin-dependent protein kinase activating kinase holoenzyme complex, cytoplasm, holo TFIIH complex, nucleoplasm, nucleus, spindle 4 iron, 4 sulfur cluster binding, 5'-3' DNA helicase activity, ATP binding, ATP-dependent DNA helicase activity, DNA binding, DNA-dependent ATPase activity, RNA polymerase II carboxy-terminal domain kinase activity, metal ion binding, protein C-terminus binding, protein N-terminus binding, protein binding, protein kinase activity Human ERCC3 IntAct UniProtKB {GO:0005515=PMID:10734143, GO:0010467=Reactome:REACT_71, GO:0009650=GO_REF:0000019, GO:0006368=Reactome:REACT_2089, GO:0006367=Reactome:REACT_1851, GO:0006366=Reactome:REACT_1366, GO:0000441=GO_REF:0000019, GO:0006363=Reactome:REACT_1074, GO:0006362=Reactome:REACT_2204, GO:0006361=Reactome:REACT_1974, GO:0006360=Reactome:REACT_1309, GO:0009411=PMID:17509950, GO:0006979=PMID:17614221, GO:0008094=PMID:9852112, GO:0032564=GO_REF:0000019, GO:0006370=Reactome:REACT_1470, GO:0006281=Reactome:REACT_216, GO:0006283=Reactome:REACT_1628, GO:0000075=PMID:17088560, GO:0043138=PMID:17466626, GO:0005654=Reactome:REACT_2233, GO:0006289=Reactome:REACT_1826, GO:0008134=PMID:9173976, GO:0035315=PMID:11335038, GO:0022415=Reactome:REACT_6361, GO:0005634=PMID:8663148, GO:0004003=GO_REF:0000019, GO:0008104=PMID:17509950, GO:0045944=PMID:8692841, GO:0016032=Reactome:REACT_6256, GO:0016887=PMID:17466626, GO:0001666=GO_REF:0000019, GO:0042277=GO_REF:0000019, GO:0006917=PMID:16914395, GO:0005525=GO_REF:0000019, GO:0008022=PMID:10801852, GO:0005524=GO_REF:0000019, GO:0008353=PMID:9852112, GO:0003677=PMID:8663148, GO:0050434=Reactome:REACT_6162, GO:0003684=PMID:2167179, GO:0047485=PMID:8652557, GO:0004672=PMID:9852112, GO:0019048=GO_REF:0000037, GO:0006468=GO_REF:0000019, GO:0000717=PMID:17466626, GO:0000718=Reactome:REACT_311, GO:0005675=PMID:8692842, GO:0006265=PMID:8663148, GO:0033683=PMID:17466626} P19447 TFIIH basal transcription factor complex helicase XPB subunit protein 20130415 {GO:0005515=IPI, GO:0010467=TAS, GO:0009650=IEA, GO:0006368=TAS, GO:0006367=TAS, GO:0006366=TAS, GO:0000441=IEA, GO:0006363=TAS, GO:0006362=TAS, GO:0006361=TAS, GO:0006360=TAS, GO:0009411=IMP, GO:0006979=IMP, GO:0008094=IDA, GO:0032564=IEA, GO:0006370=TAS, GO:0006281=TAS, GO:0006283=TAS, GO:0000075=IMP, GO:0043138=IDA, GO:0005654=TAS, GO:0006289=TAS, GO:0008134=IDA, GO:0035315=IMP, GO:0022415=TAS, GO:0005634=TAS, GO:0004003=IEA, GO:0008104=IMP, GO:0045944=IDA, GO:0016032=TAS, GO:0016887=IDA, GO:0001666=IEA, GO:0042277=IEA, GO:0006917=IDA, GO:0005525=IEA, GO:0008022=IPI, GO:0005524=IEA, GO:0008353=IDA, GO:0003677=TAS, GO:0050434=TAS, GO:0003684=NAS, GO:0047485=IPI, GO:0004672=IDA, GO:0019048=IEA, GO:0006468=IEA, GO:0000717=IMP, GO:0000718=TAS, GO:0005675=IDA, GO:0006265=IMP, GO:0033683=IMP} 7-methylguanosine mRNA capping, DNA repair, DNA topological change, UV protection, cell cycle checkpoint, gene expression, hair cell differentiation, induction of apoptosis, nucleotide-excision repair, nucleotide-excision repair, DNA damage removal, nucleotide-excision repair, DNA duplex unwinding, nucleotide-excision repair, DNA incision, positive regulation of transcription from RNA polymerase II promoter, positive regulation of viral transcription, protein localization, protein phosphorylation, response to UV, response to hypoxia, response to oxidative stress, termination of RNA polymerase I transcription, transcription elongation from RNA polymerase I promoter, transcription elongation from RNA polymerase II promoter, transcription from RNA polymerase I promoter, transcription from RNA polymerase II promoter, transcription initiation from RNA polymerase I promoter, transcription initiation from RNA polymerase II promoter, transcription-coupled nucleotide-excision repair, viral reproduction, viral reproductive process, virus-host interaction SSL2-core TFIIH complex, holo TFIIH complex, nucleoplasm, nucleus 3'-5' DNA helicase activity, ATP binding, ATP-dependent DNA helicase activity, ATPase activity, DNA binding, DNA-dependent ATPase activity, GTP binding, RNA polymerase II carboxy-terminal domain kinase activity, dATP binding, damaged DNA binding, peptide binding, protein C-terminus binding, protein N-terminus binding, protein binding, protein kinase activity, transcription factor binding Human UniProtKB:Q01831 ERCC4 BHF-UCL UniProtKB {GO:0005515=PMID:14690602, GO:0009650=GO_REF:0000019, GO:0010834=PMID:17055345, GO:0000110=PMID:10413517, GO:0005634=PMID:12571280, GO:0000109=PMID:10644440, GO:0000723=PMID:14690602, GO:0006295=PMID:11790111, GO:0003697=PMID:10413517, GO:0000724=PMID:14728600, GO:0006296=PMID:14728600, GO:0009411=PMID:16678501, GO:0000784=PMID:14690602, GO:0000781=PMID:14690602, GO:0004520=PMID:14734547, GO:0008022=PMID:9722633, GO:0003684=PMID:11790111, GO:0006281=Reactome:REACT_216, GO:0047485=PMID:14734547, GO:0000710=GO_REF:0000033, GO:0006283=Reactome:REACT_1628, GO:0000712=GO_REF:0000033, GO:0043566=PMID:14734547, GO:0000014=GO_REF:0000033, GO:0032205=PMID:17055345, GO:0005654=Reactome:REACT_2163, GO:0006289=Reactome:REACT_1826, GO:0000718=Reactome:REACT_311, GO:0033683=PMID:10413517} Q92889 DNA repair endonuclease XPF protein 20081216 {GO:0005515=IPI, GO:0009650=IEA, GO:0010834=IMP, GO:0000110=IDA, GO:0005634=IDA, GO:0000109=IDA, GO:0000723=IMP, GO:0006295=IMP, GO:0003697=IDA, GO:0000724=IMP, GO:0006296=IMP, GO:0009411=IMP, GO:0000784=IDA, GO:0000781=IDA, GO:0004520=IDA, GO:0008022=IPI, GO:0003684=IMP, GO:0006281=TAS, GO:0047485=IPI, GO:0000710=IBA, GO:0006283=TAS, GO:0000712=IBA, GO:0043566=IDA, GO:0000014=IBA, GO:0032205=IMP, GO:0005654=TAS, GO:0006289=TAS, GO:0000718=TAS, GO:0033683=IDA} DNA repair, UV protection, double-strand break repair via homologous recombination, meiotic mismatch repair, negative regulation of telomere maintenance, nucleotide-excision repair, nucleotide-excision repair, DNA damage removal, nucleotide-excision repair, DNA incision, nucleotide-excision repair, DNA incision, 3'-to lesion, nucleotide-excision repair, DNA incision, 5'-to lesion, resolution of meiotic recombination intermediates, response to UV, telomere maintenance, telomere maintenance via telomere shortening, transcription-coupled nucleotide-excision repair chromosome, telomeric region, nuclear chromosome, telomeric region, nucleoplasm, nucleotide-excision repair complex, nucleotide-excision repair factor 1 complex, nucleus damaged DNA binding, endodeoxyribonuclease activity, protein C-terminus binding, protein N-terminus binding, protein binding, single-stranded DNA binding, single-stranded DNA specific endodeoxyribonuclease activity, structure-specific DNA binding Human ERCC5 InterPro UniProtKB {GO:0005515=PMID:8652557, GO:0009650=PMID:7510366, GO:0043066=PMID:16167068, GO:0000405=PMID:16246722, GO:0004520=PMID:12644470, GO:0005634=GO_REF:0000002, GO:0008340=GO_REF:0000019, GO:0042803=PMID:10026181, GO:0046872=GO_REF:0000037, GO:0010225=PMID:17208056, GO:0003690=PMID:8090225, GO:0047485=PMID:8652557, GO:0006281=Reactome:REACT_216, GO:0004519=GO_REF:0000002, GO:0006295=PMID:7657672, GO:0003697=GO_REF:0000002, GO:0035264=GO_REF:0000019, GO:0006283=Reactome:REACT_1628, GO:0016591=PMID:16246722, GO:0005654=Reactome:REACT_2163, GO:0006289=GO_REF:0000002, GO:0000718=Reactome:REACT_311, GO:0009411=PMID:16167068, GO:0005675=PMID:11259578} Q9HD60 Xeroderma pigmentosum complementation group G protein splice variant protein 20130413 {GO:0005515=IPI, GO:0009650=IGI, GO:0043066=IMP, GO:0000405=IDA, GO:0004520=IDA, GO:0005634=IEA, GO:0008340=IEA, GO:0042803=IPI, GO:0046872=IEA, GO:0010225=IMP, GO:0003690=IDA, GO:0047485=IPI, GO:0006281=TAS, GO:0004519=IEA, GO:0006295=IMP, GO:0003697=IEA, GO:0035264=IEA, GO:0006283=TAS, GO:0016591=IDA, GO:0005654=TAS, GO:0006289=IEA, GO:0000718=TAS, GO:0009411=IMP, GO:0005675=IDA} DNA repair, UV protection, determination of adult lifespan, multicellular organism growth, negative regulation of apoptotic process, nucleotide-excision repair, nucleotide-excision repair, DNA damage removal, nucleotide-excision repair, DNA incision, 3'-to lesion, response to UV, response to UV-C, transcription-coupled nucleotide-excision repair DNA-directed RNA polymerase II, holoenzyme, holo TFIIH complex, nucleoplasm, nucleus bubble DNA binding, double-stranded DNA binding, endodeoxyribonuclease activity, endonuclease activity, metal ion binding, protein N-terminus binding, protein binding, protein homodimerization activity, single-stranded DNA binding Human InterPro:IPR001044 ERCC6 IntAct UniProtKB {GO:0005515=PMID:7664335, GO:0010165=GO_REF:0000019, GO:0006366=PMID:7664335, GO:0005634=PMID:12560492, GO:0045494=GO_REF:0000019, GO:0032403=PMID:16916636, GO:0032786=PMID:9326587, GO:0006290=GO_REF:0000019, GO:0032784=PMID:9326587, GO:0006979=PMID:16107709, GO:0010332=GO_REF:0000019, GO:0009411=PMID:16916636, GO:0008094=PMID:12560492, GO:0008630=GO_REF:0000019, GO:0004386=GO_REF:0000002, GO:0005730=PMID:16107709, GO:0009636=GO_REF:0000019, GO:0007256=GO_REF:0000019, GO:0007257=GO_REF:0000019, GO:0008022=PMID:16246722, GO:0008023=PMID:9326587, GO:0003677=PMID:16107709, GO:0005524=PMID:12560492, GO:0003678=PMID:8999876, GO:0006281=Reactome:REACT_216, GO:0047485=PMID:7664335, GO:0010224=GO_REF:0000019, GO:0006283=Reactome:REACT_1628, GO:0003682=PMID:16916636, GO:0006284=PMID:9973627, GO:0000303=GO_REF:0000019, GO:0005654=Reactome:REACT_1584, GO:0006289=Reactome:REACT_1826} Q03468 DNA excision repair protein ERCC-6 protein 20130415 {GO:0005515=IPI, GO:0010165=IEA, GO:0006366=NAS, GO:0005634=IDA, GO:0045494=IEA, GO:0032403=IDA, GO:0032786=IDA, GO:0006290=IEA, GO:0032784=IDA, GO:0006979=IDA, GO:0010332=IEA, GO:0009411=IDA, GO:0008094=IDA, GO:0008630=IEA, GO:0004386=IEA, GO:0005730=IDA, GO:0009636=IEA, GO:0007256=IEA, GO:0007257=IEA, GO:0008022=IPI, GO:0008023=IDA, GO:0003677=IDA, GO:0005524=IDA, GO:0003678=IDA, GO:0006281=TAS, GO:0047485=IPI, GO:0010224=IEA, GO:0006283=TAS, GO:0003682=IDA, GO:0006284=IMP, GO:0000303=IEA, GO:0005654=TAS, GO:0006289=TAS} DNA repair, activation of JNKK activity, activation of JUN kinase activity, base-excision repair, intrinsic apoptotic signaling pathway in response to DNA damage, nucleotide-excision repair, photoreceptor cell maintenance, positive regulation of DNA-dependent transcription, elongation, pyrimidine dimer repair, regulation of DNA-dependent transcription, elongation, response to UV, response to UV-B, response to X-ray, response to gamma radiation, response to oxidative stress, response to superoxide, response to toxic substance, transcription from RNA polymerase II promoter, transcription-coupled nucleotide-excision repair nucleolus, nucleoplasm, nucleus, transcription elongation factor complex ATP binding, DNA binding, DNA helicase activity, DNA-dependent ATPase activity, chromatin binding, helicase activity, protein C-terminus binding, protein N-terminus binding, protein binding, protein complex binding Human UniProtKB:Q13216-1 ERCC6L IntAct UniProtKB {GO:0005515=PMID:23275563, GO:0000236=Reactome:REACT_682, GO:0000087=Reactome:REACT_910, GO:0000777=GO_REF:0000039, GO:0004386=GO_REF:0000037, GO:0000278=Reactome:REACT_152, GO:0000090=Reactome:REACT_1275, GO:0005524=GO_REF:0000037, GO:0003677=GO_REF:0000037, GO:0005829=Reactome:REACT_150414, GO:0051301=GO_REF:0000037} Q2NKX8 DNA excision repair protein ERCC-6-like protein 20130415 {GO:0005515=IPI, GO:0000236=TAS, GO:0000087=TAS, GO:0000777=IEA, GO:0004386=IEA, GO:0000278=TAS, GO:0000090=TAS, GO:0005524=IEA, GO:0003677=IEA, GO:0005829=TAS, GO:0051301=IEA} M phase of mitotic cell cycle, cell division, mitotic anaphase, mitotic cell cycle, mitotic prometaphase condensed chromosome kinetochore, cytosol ATP binding, DNA binding, helicase activity, protein binding Human UniProtKB:P42858 ERCC8 IntAct UniProtKB {GO:0000209=PMID:12732143, GO:0005515=PMID:10944529, GO:0004842=PMID:12732143, GO:0010165=GO_REF:0000019, GO:0005634=PMID:11782547, GO:0032403=PMID:16916636, GO:0016363=PMID:11782547, GO:0006974=PMID:11782547, GO:0003678=PMID:8999876, GO:0051865=PMID:12732143, GO:0043234=PMID:12732143, GO:0000109=PMID:12732143, GO:0006281=Reactome:REACT_216, GO:0006283=Reactome:REACT_1628, GO:0005654=Reactome:REACT_1584, GO:0043161=PMID:16751180, GO:0031464=PMID:12732143, GO:0006289=Reactome:REACT_1826, GO:0009411=PMID:12732143, GO:0006979=PMID:11782547, GO:0008094=PMID:8999876} Q13216 DNA excision repair protein ERCC-8 protein 20130415 {GO:0000209=IDA, GO:0005515=IPI, GO:0004842=IDA, GO:0010165=IEA, GO:0005634=IDA, GO:0032403=IDA, GO:0016363=IDA, GO:0006974=IDA, GO:0003678=IDA, GO:0051865=IDA, GO:0043234=IDA, GO:0000109=IDA, GO:0006281=TAS, GO:0006283=TAS, GO:0005654=TAS, GO:0043161=IDA, GO:0031464=IDA, GO:0006289=TAS, GO:0009411=IDA, GO:0006979=IDA, GO:0008094=IDA} DNA repair, nucleotide-excision repair, proteasomal ubiquitin-dependent protein catabolic process, protein autoubiquitination, protein polyubiquitination, response to DNA damage stimulus, response to UV, response to X-ray, response to oxidative stress, transcription-coupled nucleotide-excision repair Cul4A-RING ubiquitin ligase complex, nuclear matrix, nucleoplasm, nucleotide-excision repair complex, nucleus, protein complex DNA helicase activity, DNA-dependent ATPase activity, protein binding, protein complex binding, ubiquitin-protein ligase activity Human UniProtKB:Q9HCS7 EREG Reactome UniProtKB {GO:0005515=PMID:9419975, GO:0008284=GO_REF:0000024, GO:0005154=PMID:10681561, GO:0008285=GO_REF:0000024, GO:0019221=PMID:9419975, GO:0042700=GO_REF:0000024, GO:0050680=PMID:10681561, GO:0007267=PMID:14581411, GO:0043434=GO_REF:0000019, GO:0001819=GO_REF:0000024, GO:0001556=GO_REF:0000024, GO:0048146=PMID:12702554, GO:0005615=PMID:14581411, GO:0009653=PMID:9337852, GO:0007173=Reactome:REACT_9417, GO:0045860=PMID:14581411, GO:0009887=PMID:9337852, GO:0051781=GO_REF:0000037, GO:0048160=GO_REF:0000024, GO:0042108=PMID:10681561, GO:0045410=GO_REF:0000024, GO:0048011=Reactome:REACT_11061, GO:0051151=PMID:14581411, GO:0048015=Reactome:REACT_12464, GO:0045741=PMID:9990076, GO:0045740=PMID:9337852, GO:0005576=Reactome:REACT_147854, GO:0045840=GO_REF:0000024, GO:0001525=GO_REF:0000037, GO:0048661=PMID:9990076, GO:0043616=PMID:10681561, GO:0045089=GO_REF:0000024, GO:0008543=Reactome:REACT_9470, GO:0005887=PMID:9337852, GO:0030216=PMID:10681561, GO:0045087=Reactome:REACT_6802, GO:0001550=GO_REF:0000024, GO:0042060=PMID:12898511, GO:0009299=PMID:10681561, GO:0007143=GO_REF:0000024, GO:0045892=PMID:14581411, GO:0008083=GO_REF:0000037, GO:0030728=GO_REF:0000024, GO:0042327=PMID:9419975} O14944 Proepiregulin protein 20130301 {GO:0005515=IPI, GO:0008284=ISS, GO:0005154=TAS, GO:0008285=ISS, GO:0019221=IDA, GO:0042700=ISS, GO:0050680=TAS, GO:0007267=IDA, GO:0043434=IEA, GO:0001819=ISS, GO:0001556=ISS, GO:0048146=IDA, GO:0005615=IDA, GO:0009653=TAS, GO:0007173=TAS, GO:0045860=IDA, GO:0009887=TAS, GO:0051781=IEA, GO:0048160=ISS, GO:0042108=IDA, GO:0045410=ISS, GO:0048011=TAS, GO:0051151=IDA, GO:0048015=TAS, GO:0045741=ISS, GO:0045740=IDA, GO:0005576=TAS, GO:0045840=ISS, GO:0001525=IEA, GO:0048661=ISS, GO:0043616=IDA, GO:0045089=ISS, GO:0008543=TAS, GO:0005887=TAS, GO:0030216=TAS, GO:0045087=TAS, GO:0001550=ISS, GO:0042060=TAS, GO:0009299=IDA, GO:0007143=ISS, GO:0045892=IDA, GO:0008083=IEA, GO:0030728=ISS, GO:0042327=IDA} anatomical structure morphogenesis, angiogenesis, cell-cell signaling, cytokine-mediated signaling pathway, epidermal growth factor receptor signaling pathway, female meiosis, fibroblast growth factor receptor signaling pathway, innate immune response, keratinocyte differentiation, keratinocyte proliferation, luteinizing hormone signaling pathway, mRNA transcription, negative regulation of cell proliferation, negative regulation of epithelial cell proliferation, negative regulation of smooth muscle cell differentiation, negative regulation of transcription, DNA-dependent, neurotrophin TRK receptor signaling pathway, oocyte maturation, organ morphogenesis, ovarian cumulus expansion, ovulation, phosphatidylinositol-mediated signaling, positive regulation of DNA replication, positive regulation of cell division, positive regulation of cell proliferation, positive regulation of cytokine biosynthetic process, positive regulation of cytokine production, positive regulation of epidermal growth factor-activated receptor activity, positive regulation of fibroblast proliferation, positive regulation of innate immune response, positive regulation of interleukin-6 biosynthetic process, positive regulation of mitosis, positive regulation of phosphorylation, positive regulation of protein kinase activity, positive regulation of smooth muscle cell proliferation, primary follicle stage, response to peptide hormone stimulus, wound healing extracellular region, extracellular space, integral to plasma membrane epidermal growth factor receptor binding, growth factor activity, protein binding Human ERF UniProtKB UniProtKB {GO:0043565=GO_REF:0000002, GO:0007049=PMID:7588608, GO:0060710=GO_REF:0000019, GO:0003700=GO_REF:0000002, GO:0003714=PMID:7588608, GO:0060707=GO_REF:0000019, GO:0005634=GO_REF:0000039, GO:0000122=PMID:7588608, GO:0010668=GO_REF:0000019, GO:0006351=GO_REF:0000037} P50548 ETS domain-containing transcription factor ERF protein 20120606 {GO:0043565=IEA, GO:0007049=NAS, GO:0060710=IEA, GO:0003700=IEA, GO:0003714=IDA, GO:0060707=IEA, GO:0005634=IEA, GO:0000122=IDA, GO:0010668=IEA, GO:0006351=IEA} cell cycle, chorio-allantoic fusion, ectodermal cell differentiation, negative regulation of transcription from RNA polymerase II promoter, transcription, DNA-dependent, trophoblast giant cell differentiation nucleus sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, transcription corepressor activity Human ERG IntAct UniProtKB {GO:0005515=PMID:21575865, GO:0003700=GO_REF:0000002, GO:0008283=PMID:3476934, GO:0005634=GO_REF:0000039, GO:0007275=PMID:8502479, GO:0003677=PMID:8502479, GO:0006351=GO_REF:0000037, GO:0043565=GO_REF:0000002, GO:0007165=PMID:8502479, GO:0005737=GO_REF:0000039, GO:0030529=PMID:17289661, GO:0006468=PMID:8502479, GO:0004871=PMID:8502479} P11308 Transcriptional regulator ERG protein 20130415 {GO:0005515=IPI, GO:0003700=IEA, GO:0008283=TAS, GO:0005634=IEA, GO:0007275=TAS, GO:0003677=TAS, GO:0006351=IEA, GO:0043565=IEA, GO:0007165=TAS, GO:0005737=IEA, GO:0030529=IDA, GO:0006468=TAS, GO:0004871=TAS} cell proliferation, multicellular organismal development, protein phosphorylation, signal transduction, transcription, DNA-dependent cytoplasm, nucleus, ribonucleoprotein complex DNA binding, protein binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, signal transducer activity Human UniProtKB:P09874 ERGIC1 HGNC UniProtKB {GO:0005515=PMID:15308636, GO:0006888=PMID:15308636, GO:0005793=PMID:15308636, GO:0000139=GO_REF:0000039, GO:0033116=GO_REF:0000039, GO:0005789=GO_REF:0000039, GO:0016021=GO_REF:0000037} Q969X5 Endoplasmic reticulum-Golgi intermediate compartment protein 1 protein 20060104 {GO:0005515=IPI, GO:0006888=IDA, GO:0005793=IDA, GO:0000139=IEA, GO:0033116=IEA, GO:0005789=IEA, GO:0016021=IEA} ER to Golgi vesicle-mediated transport Golgi membrane, endoplasmic reticulum membrane, endoplasmic reticulum-Golgi intermediate compartment, endoplasmic reticulum-Golgi intermediate compartment membrane, integral to membrane protein binding Human UniProtKB:O95330 ERGIC2 UniProtKB UniProtKB {GO:0005794=GO_REF:0000039, GO:0033116=GO_REF:0000039, GO:0005789=GO_REF:0000039, GO:0005634=GO_REF:0000039, GO:0016021=GO_REF:0000037, GO:0016192=GO_REF:0000037} Q96RQ1 Endoplasmic reticulum-Golgi intermediate compartment protein 2 protein 20130413 {GO:0005794=IEA, GO:0033116=IEA, GO:0005789=IEA, GO:0005634=IEA, GO:0016021=IEA, GO:0016192=IEA} vesicle-mediated transport Golgi apparatus, endoplasmic reticulum membrane, endoplasmic reticulum-Golgi intermediate compartment membrane, integral to membrane, nucleus Human UniProtKB-SubCell:SL-0099 ERGIC3 UniProtKB UniProtKB {GO:0005794=GO_REF:0000039, GO:0033116=GO_REF:0000039, GO:0005789=GO_REF:0000039, GO:0016021=GO_REF:0000037, GO:0016192=GO_REF:0000037} Q9Y282 Endoplasmic reticulum-Golgi intermediate compartment protein 3 protein 20130413 {GO:0005794=IEA, GO:0033116=IEA, GO:0005789=IEA, GO:0016021=IEA, GO:0016192=IEA} vesicle-mediated transport Golgi apparatus, endoplasmic reticulum membrane, endoplasmic reticulum-Golgi intermediate compartment membrane, integral to membrane Human UniProtKB-SubCell:SL-0099 ERH PINC UniProtKB {GO:0006213=PMID:8786099, GO:0006139=PMID:9074495, GO:0007049=GO_REF:0000037, GO:0030496=PMID:15166316} P84090 Enhancer of rudimentary homolog protein 20040715 {GO:0006213=TAS, GO:0006139=TAS, GO:0007049=IEA, GO:0030496=IDA} cell cycle, nucleobase-containing compound metabolic process, pyrimidine nucleoside metabolic process midbody Human ERI1 UniProtKB UniProtKB {GO:0005737=PMID:16912046, GO:0008408=PMID:16912046, GO:0071044=PMID:18172165, GO:0005730=PMID:16912046, GO:0043022=GO_REF:0000024, GO:0005634=GO_REF:0000024, GO:0019843=GO_REF:0000024, GO:0071204=GO_REF:0000024, GO:0031047=GO_REF:0000037, GO:0071207=GO_REF:0000024, GO:0046872=GO_REF:0000037, GO:0031125=GO_REF:0000024} Q8IV48 3'-5' exoribonuclease 1 protein 20090116 {GO:0005737=IDA, GO:0008408=IDA, GO:0071044=IMP, GO:0005730=IDA, GO:0043022=ISS, GO:0005634=ISS, GO:0019843=ISS, GO:0071204=ISS, GO:0031047=IEA, GO:0071207=ISS, GO:0046872=IEA, GO:0031125=ISS} gene silencing by RNA, histone mRNA catabolic process, rRNA 3'-end processing cytoplasm, histone pre-mRNA 3'end processing complex, nucleolus, nucleus 3'-5' exonuclease activity, histone pre-mRNA stem-loop binding, metal ion binding, rRNA binding, ribosome binding Human UniProtKB:Q7TMF2 ERI3 UniProtKB UniProtKB {GO:0005622=GO_REF:0000002, GO:0004527=GO_REF:0000037, GO:0003676=GO_REF:0000002, GO:0046872=GO_REF:0000037} O43414 ERI1 exoribonuclease 3 protein 20130413 {GO:0005622=IEA, GO:0004527=IEA, GO:0003676=IEA, GO:0046872=IEA} intracellular exonuclease activity, metal ion binding, nucleic acid binding Human UniProtKB-KW:KW-0479 ERICH1 null null {} null null null null {} null null null ERLEC1 UniProtKB UniProtKB {GO:0005515=PMID:18502753, GO:0001948=PMID:16531414, GO:0005788=PMID:16531414} Q96DZ1 Endoplasmic reticulum lectin 1 protein 20120708 {GO:0005515=IPI, GO:0001948=IDA, GO:0005788=IDA} endoplasmic reticulum lumen glycoprotein binding, protein binding Human UniProtKB:Q13438 ERLIN1 HPA UniProtKB {GO:0005515=PMID:19240031, GO:0043234=PMID:18468998, GO:0005783=GO_REF:0000052, GO:0005789=PMID:16835267, GO:0016021=GO_REF:0000037, GO:0030433=PMID:19240031} O75477 Erlin-1 protein 20081203 {GO:0005515=IPI, GO:0043234=IDA, GO:0005783=IDA, GO:0005789=IDA, GO:0016021=IEA, GO:0030433=IDA} ER-associated protein catabolic process endoplasmic reticulum, endoplasmic reticulum membrane, integral to membrane, protein complex protein binding Human ERLIN2 HPA UniProtKB {GO:0005515=PMID:19240031, GO:0043234=PMID:18468998, GO:0008219=GO_REF:0000037, GO:0005737=GO_REF:0000052, GO:0005886=GO_REF:0000052, GO:0005783=GO_REF:0000052, GO:0005789=PMID:16835267, GO:0016021=GO_REF:0000037, GO:0030433=PMID:19240031} O94905 Erlin-2 protein 20101115 {GO:0005515=IPI, GO:0043234=IDA, GO:0008219=IEA, GO:0005737=IDA, GO:0005886=IDA, GO:0005783=IDA, GO:0005789=IDA, GO:0016021=IEA, GO:0030433=IDA} ER-associated protein catabolic process, cell death cytoplasm, endoplasmic reticulum, endoplasmic reticulum membrane, integral to membrane, plasma membrane, protein complex protein binding Human ERMAP MGI UniProtKB {GO:0005886=PMID:11549310, GO:0031410=GO_REF:0000019, GO:0016021=GO_REF:0000037} Q96PL5 Erythroid membrane-associated protein protein 20040716 {GO:0005886=IDA, GO:0031410=IEA, GO:0016021=IEA} cytoplasmic vesicle, integral to membrane, plasma membrane Human ERMN UniProtKB UniProtKB {GO:0005737=GO_REF:0000037, GO:0033269=GO_REF:0000019, GO:0031344=GO_REF:0000019, GO:0051015=GO_REF:0000019, GO:0043209=GO_REF:0000019, GO:0008360=GO_REF:0000019, GO:0043025=GO_REF:0000019, GO:0033270=GO_REF:0000019, GO:0007015=GO_REF:0000019, GO:0030175=GO_REF:0000019, GO:0005856=GO_REF:0000039, GO:0001763=GO_REF:0000019} Q8TAM6 Ermin protein 20130413 {GO:0005737=IEA, GO:0033269=IEA, GO:0031344=IEA, GO:0051015=IEA, GO:0043209=IEA, GO:0008360=IEA, GO:0043025=IEA, GO:0033270=IEA, GO:0007015=IEA, GO:0030175=IEA, GO:0005856=IEA, GO:0001763=IEA} actin filament organization, morphogenesis of a branching structure, regulation of cell projection organization, regulation of cell shape cytoplasm, cytoskeleton, filopodium, internode region of axon, myelin sheath, neuronal cell body, paranode region of axon actin filament binding Human UniProtKB-SubCell:SL-0090 ERMP1 UniProtKB UniProtKB {GO:0005789=GO_REF:0000039, GO:0006508=GO_REF:0000037, GO:0008233=GO_REF:0000002, GO:0016021=GO_REF:0000037, GO:0046872=GO_REF:0000037, GO:0008237=GO_REF:0000037} Q7Z2K6 Endoplasmic reticulum metallopeptidase 1 protein 20130413 {GO:0005789=IEA, GO:0006508=IEA, GO:0008233=IEA, GO:0016021=IEA, GO:0046872=IEA, GO:0008237=IEA} proteolysis endoplasmic reticulum membrane, integral to membrane metal ion binding, metallopeptidase activity, peptidase activity Human UniProtKB-SubCell:SL-0097 ERN1 IntAct UniProtKB {GO:0005515=PMID:16645094, GO:0006397=GO_REF:0000002, GO:0006355=GO_REF:0000037, GO:0000287=PMID:9637683, GO:0006915=GO_REF:0000037, GO:0005637=GO_REF:0000019, GO:0030176=PMID:9637683, GO:0004521=Reactome:REACT_22313, GO:0006917=GO_REF:0000024, GO:0005524=PMID:9637683, GO:0006351=GO_REF:0000037, GO:0030968=Reactome:REACT_18356, GO:0046777=GO_REF:0000019, GO:0004674=Reactome:REACT_18399, GO:0005789=Reactome:REACT_22313, GO:0007050=GO_REF:0000024, GO:0006468=PMID:9637683, GO:0006987=Reactome:REACT_18368, GO:0044267=Reactome:REACT_17015} O75460 Serine/threonine-protein kinase/endoribonuclease IRE1 protein 20130415 {GO:0005515=IPI, GO:0006397=IEA, GO:0006355=IEA, GO:0000287=IDA, GO:0006915=IEA, GO:0005637=IEA, GO:0030176=IDA, GO:0004521=TAS, GO:0006917=ISS, GO:0005524=IDA, GO:0006351=IEA, GO:0030968=TAS, GO:0046777=IEA, GO:0004674=TAS, GO:0005789=TAS, GO:0007050=ISS, GO:0006468=IDA, GO:0006987=TAS, GO:0044267=TAS} activation of signaling protein activity involved in unfolded protein response, apoptotic process, cell cycle arrest, cellular protein metabolic process, endoplasmic reticulum unfolded protein response, induction of apoptosis, mRNA processing, protein autophosphorylation, protein phosphorylation, regulation of transcription, DNA-dependent, transcription, DNA-dependent endoplasmic reticulum membrane, integral to endoplasmic reticulum membrane, nuclear inner membrane ATP binding, endoribonuclease activity, magnesium ion binding, protein binding, protein serine/threonine kinase activity Human UniProtKB:Q07813 ERO1L Reactome UniProtKB {GO:0034976=GO_REF:0000024, GO:0051209=GO_REF:0000024, GO:0005783=PMID:10671517, GO:0050660=GO_REF:0000002, GO:0003756=GO_REF:0000002, GO:0043231=PMID:10671517, GO:0030968=GO_REF:0000019, GO:0009266=PMID:10671517, GO:0016020=PMID:10671517, GO:0006457=PMID:10671517, GO:0050873=GO_REF:0000019, GO:0070059=GO_REF:0000024, GO:0016491=PMID:11707400, GO:0051085=PMID:11707400, GO:0005789=GO_REF:0000039, GO:0016671=GO_REF:0000002, GO:0005788=Reactome:REACT_15454, GO:0022900=GO_REF:0000037, GO:0044267=Reactome:REACT_17015, GO:0006464=PMID:10671517} Q96HE7 ERO1-like protein alpha protein 20130301 {GO:0034976=ISS, GO:0051209=ISS, GO:0005783=IDA, GO:0050660=IEA, GO:0003756=IEA, GO:0043231=TAS, GO:0030968=IEA, GO:0009266=TAS, GO:0016020=TAS, GO:0006457=TAS, GO:0050873=IEA, GO:0070059=ISS, GO:0016491=IDA, GO:0051085=IDA, GO:0005789=IEA, GO:0016671=IEA, GO:0005788=TAS, GO:0022900=IEA, GO:0044267=TAS, GO:0006464=TAS} brown fat cell differentiation, cellular protein metabolic process, cellular protein modification process, chaperone mediated protein folding requiring cofactor, electron transport chain, endoplasmic reticulum unfolded protein response, intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress, protein folding, release of sequestered calcium ion into cytosol, response to endoplasmic reticulum stress, response to temperature stimulus endoplasmic reticulum, endoplasmic reticulum lumen, endoplasmic reticulum membrane, intracellular membrane-bounded organelle, membrane flavin adenine dinucleotide binding, oxidoreductase activity, oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor, protein disulfide isomerase activity Human ERO1LB UniProtKB UniProtKB {GO:0006457=PMID:10818100, GO:0005783=PMID:10818100, GO:0050660=GO_REF:0000002, GO:0016491=PMID:10818100, GO:0016671=GO_REF:0000002, GO:0005789=GO_REF:0000039, GO:0003756=GO_REF:0000002, GO:0051082=PMID:10818100, GO:0022900=GO_REF:0000037} Q86YB8 ERO1-like protein beta protein 20050308 {GO:0006457=TAS, GO:0005783=TAS, GO:0050660=IEA, GO:0016491=NAS, GO:0016671=IEA, GO:0005789=IEA, GO:0003756=IEA, GO:0051082=NAS, GO:0022900=IEA} electron transport chain, protein folding endoplasmic reticulum, endoplasmic reticulum membrane flavin adenine dinucleotide binding, oxidoreductase activity, oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor, protein disulfide isomerase activity, unfolded protein binding Human ERP27 UniProtKB UniProtKB {GO:0005788=GO_REF:0000039} Q96DN0 Endoplasmic reticulum resident protein 27 protein 20130413 {GO:0005788=IEA} endoplasmic reticulum lumen Human UniProtKB-SubCell:SL-0096 ERP29 PINC UniProtKB {GO:0042470=GO_REF:0000039, GO:0009306=GO_REF:0000002, GO:0009986=PMID:19995400, GO:0006457=PMID:9738895, GO:0005783=PMID:9738895, GO:0003756=PMID:9738895, GO:0005788=GO_REF:0000039, GO:0006886=PMID:9738895} P30040 Endoplasmic reticulum resident protein 29 protein 20030904 {GO:0042470=IEA, GO:0009306=IEA, GO:0009986=IDA, GO:0006457=TAS, GO:0005783=TAS, GO:0003756=TAS, GO:0005788=IEA, GO:0006886=TAS} intracellular protein transport, protein folding, protein secretion cell surface, endoplasmic reticulum, endoplasmic reticulum lumen, melanosome protein disulfide isomerase activity Human ERP44 MGI UniProtKB {GO:0006986=PMID:11847130, GO:0009100=PMID:11847130, GO:0005793=PMID:15308636, GO:0009986=PMID:19995400, GO:0006457=PMID:11847130, GO:0005789=PMID:11847130, GO:0006950=PMID:11847130, GO:0005788=PMID:11847130, GO:0003756=PMID:11847130, GO:0045454=PMID:11847130} Q9BS26 Endoplasmic reticulum resident protein 44 protein 20120926 {GO:0006986=IDA, GO:0009100=IDA, GO:0005793=IDA, GO:0009986=IDA, GO:0006457=IDA, GO:0005789=IDA, GO:0006950=IDA, GO:0005788=IDA, GO:0003756=IDA, GO:0045454=TAS} cell redox homeostasis, glycoprotein metabolic process, protein folding, response to stress, response to unfolded protein cell surface, endoplasmic reticulum lumen, endoplasmic reticulum membrane, endoplasmic reticulum-Golgi intermediate compartment protein disulfide isomerase activity Human ERRFI1 GOC UniProtKB {GO:0005515=PMID:21988832, GO:0060426=GO_REF:0000024, GO:0060428=GO_REF:0000024, GO:0048286=GO_REF:0000024, GO:0019901=PMID:18046415, GO:0006950=PMID:10749885, GO:0005634=GO_REF:0000039, GO:0005100=PMID:10749885, GO:0031234=GO_REF:0000024, GO:0031953=PMID:18046415, GO:0045616=GO_REF:0000024, GO:0005737=GO_REF:0000052, GO:0032321=PMID:10749885, GO:0007175=PMID:18046415, GO:0043589=GO_REF:0000024} Q9UJM3 ERBB receptor feedback inhibitor 1 protein 20130413 {GO:0005515=IPI, GO:0060426=ISS, GO:0060428=ISS, GO:0048286=ISS, GO:0019901=IPI, GO:0006950=TAS, GO:0005634=IEA, GO:0005100=TAS, GO:0031234=ISS, GO:0031953=IDA, GO:0045616=ISS, GO:0005737=IDA, GO:0032321=TAS, GO:0007175=IDA, GO:0043589=ISS} lung alveolus development, lung epithelium development, lung vasculature development, negative regulation of epidermal growth factor-activated receptor activity, negative regulation of protein autophosphorylation, positive regulation of Rho GTPase activity, regulation of keratinocyte differentiation, response to stress, skin morphogenesis cytoplasm, extrinsic to internal side of plasma membrane, nucleus Rho GTPase activator activity, protein binding, protein kinase binding Human ESAM Reactome UniProtKB {GO:0005886=Reactome:REACT_12081, GO:0005912=GO_REF:0000039, GO:0007596=Reactome:REACT_604, GO:0005923=GO_REF:0000039, GO:0016021=GO_REF:0000037, GO:0050900=Reactome:REACT_12051, GO:0007156=GO_REF:0000019} Q96AP7 Endothelial cell-selective adhesion molecule protein 20130301 {GO:0005886=TAS, GO:0005912=IEA, GO:0007596=TAS, GO:0005923=IEA, GO:0016021=IEA, GO:0050900=TAS, GO:0007156=IEA} blood coagulation, homophilic cell adhesion, leukocyte migration adherens junction, integral to membrane, plasma membrane, tight junction Human ESCO1 Reactome UniProtKB {GO:0000084=Reactome:REACT_899, GO:0016746=GO_REF:0000037, GO:0034421=PMID:21111234, GO:0005654=Reactome:REACT_150456, GO:0000278=Reactome:REACT_152, GO:0000785=PMID:19907496, GO:0006275=PMID:19907496, GO:0046872=GO_REF:0000037} Q5FWF5 N-acetyltransferase ESCO1 protein 20120913 {GO:0000084=TAS, GO:0016746=IEA, GO:0034421=IMP, GO:0005654=TAS, GO:0000278=TAS, GO:0000785=IDA, GO:0006275=IMP, GO:0046872=IEA} S phase of mitotic cell cycle, mitotic cell cycle, post-translational protein acetylation, regulation of DNA replication chromatin, nucleoplasm metal ion binding, transferase activity, transferring acyl groups Human ESCO2 Reactome UniProtKB {GO:0000084=Reactome:REACT_899, GO:0016746=GO_REF:0000037, GO:0034421=PMID:21111234, GO:0005654=Reactome:REACT_150456, GO:0000278=Reactome:REACT_152, GO:0000785=PMID:19907496, GO:0046872=GO_REF:0000037, GO:0006275=PMID:19907496} Q56NI9 N-acetyltransferase ESCO2 protein 20120913 {GO:0000084=TAS, GO:0016746=IEA, GO:0034421=IMP, GO:0005654=TAS, GO:0000278=TAS, GO:0000785=IDA, GO:0046872=IEA, GO:0006275=IMP} S phase of mitotic cell cycle, mitotic cell cycle, post-translational protein acetylation, regulation of DNA replication chromatin, nucleoplasm metal ion binding, transferase activity, transferring acyl groups Human ESD HPA UniProtKB {GO:0004091=PMID:3164702, GO:0008150=GO_REF:0000015, GO:0005737=GO_REF:0000052, GO:0005794=GO_REF:0000052, GO:0046294=GO_REF:0000002, GO:0016023=GO_REF:0000029, GO:0005634=GO_REF:0000052, GO:0047374=GO_REF:0000003, GO:0018738=GO_REF:0000003} P10768 S-formylglutathione hydrolase protein 20110516 {GO:0004091=NAS, GO:0008150=ND, GO:0005737=IDA, GO:0005794=IDA, GO:0046294=IEA, GO:0016023=NAS, GO:0005634=IDA, GO:0047374=IEA, GO:0018738=IEA} biological_process, formaldehyde catabolic process Golgi apparatus, cytoplasm, cytoplasmic membrane-bounded vesicle, nucleus S-formylglutathione hydrolase activity, carboxylesterase activity, methylumbelliferyl-acetate deacetylase activity Human ESF1 UniProtKB UniProtKB {GO:0006355=GO_REF:0000037, GO:0005730=GO_REF:0000039, GO:0005654=GO_REF:0000039, GO:0006351=GO_REF:0000037} Q9H501 ESF1 homolog protein 20130413 {GO:0006355=IEA, GO:0005730=IEA, GO:0005654=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleolus, nucleoplasm Human UniProtKB-SubCell:SL-0188 ESM1 UniProtKB UniProtKB {GO:0005576=GO_REF:0000029, GO:0001525=PMID:11866539, GO:0008083=GO_REF:0000029, GO:0001558=GO_REF:0000002, GO:0005520=GO_REF:0000002} Q9NQ30 Endothelial cell-specific molecule 1 protein 20110330 {GO:0005576=NAS, GO:0001525=IEP, GO:0008083=NAS, GO:0001558=IEA, GO:0005520=IEA} angiogenesis, regulation of cell growth extracellular region growth factor activity, insulin-like growth factor binding Human ESPL1 Reactome UniProtKB {GO:0005515=PMID:12672959, GO:0005813=PMID:12672959, GO:0045842=PMID:12672959, GO:0006915=PMID:11875078, GO:0005634=GO_REF:0000039, GO:0003824=PMID:12672959, GO:0045875=PMID:12194817, GO:0000212=GO_REF:0000019, GO:0005829=Reactome:REACT_150369, GO:0000910=PMID:11509732, GO:0000070=PMID:12672959, GO:0045143=GO_REF:0000019, GO:0040001=PMID:12672959, GO:0000087=Reactome:REACT_910, GO:0006508=GO_REF:0000037, GO:0008233=GO_REF:0000019, GO:0008234=Reactome:REACT_150369, GO:0000278=Reactome:REACT_152, GO:0000090=Reactome:REACT_1275} Q14674 Separin protein 20120913 {GO:0005515=IPI, GO:0005813=IDA, GO:0045842=NAS, GO:0006915=TAS, GO:0005634=IEA, GO:0003824=NAS, GO:0045875=NAS, GO:0000212=IEA, GO:0005829=TAS, GO:0000910=NAS, GO:0000070=IMP, GO:0045143=IEA, GO:0040001=NAS, GO:0000087=TAS, GO:0006508=IEA, GO:0008233=IEA, GO:0008234=TAS, GO:0000278=TAS, GO:0000090=TAS} M phase of mitotic cell cycle, apoptotic process, cytokinesis, establishment of mitotic spindle localization, homologous chromosome segregation, meiotic spindle organization, mitotic anaphase, mitotic cell cycle, mitotic sister chromatid segregation, negative regulation of sister chromatid cohesion, positive regulation of mitotic metaphase/anaphase transition, proteolysis centrosome, cytosol, nucleus catalytic activity, cysteine-type peptidase activity, peptidase activity, protein binding Human ESPN UniProtKB UniProtKB {GO:0005903=PMID:9763424, GO:0017124=PMID:12598619, GO:0005737=GO_REF:0000019, GO:0051015=PMID:8799813, GO:0031941=PMID:8799813, GO:0051494=GO_REF:0000019, GO:0030046=GO_REF:0000019, GO:0007605=GO_REF:0000037, GO:0032420=GO_REF:0000039, GO:0051491=GO_REF:0000019, GO:0007626=GO_REF:0000019, GO:0032426=GO_REF:0000019} B1AK53 Espin protein 20091215 {GO:0005903=ISS, GO:0017124=ISS, GO:0005737=IEA, GO:0051015=ISS, GO:0031941=ISS, GO:0051494=IEA, GO:0030046=IEA, GO:0007605=IEA, GO:0032420=IEA, GO:0051491=IEA, GO:0007626=IEA, GO:0032426=IEA} locomotory behavior, negative regulation of cytoskeleton organization, parallel actin filament bundle assembly, positive regulation of filopodium assembly, sensory perception of sound brush border, cytoplasm, filamentous actin, stereocilium, stereocilium bundle tip SH3 domain binding, actin filament binding Human UniProtKB:Q63618 ESR1 UniProtKB UniProtKB {GO:0005515=PMID:17363140, GO:0010467=Reactome:REACT_71, GO:0043627=PMID:11581164, GO:0003700=GO_REF:0000002, GO:0006367=Reactome:REACT_15525, GO:0008013=PMID:15304487, GO:0060750=GO_REF:0000019, GO:0003707=PMID:11004670, GO:0042802=PMID:21182205, GO:0002064=GO_REF:0000019, GO:0004879=GO_REF:0000019, GO:0005496=GO_REF:0000002, GO:0032355=PMID:15304487, GO:0043124=PMID:16043358, GO:0005794=GO_REF:0000039, GO:0071391=GO_REF:0000019, GO:0060687=GO_REF:0000019, GO:0001547=GO_REF:0000019, GO:0048386=PMID:15831516, GO:0008270=GO_REF:0000002, GO:0005654=Reactome:REACT_116083, GO:0019899=PMID:12039952, GO:0008134=GO_REF:0000019, GO:0060065=GO_REF:0000019, GO:0005886=PMID:15569929, GO:0060068=GO_REF:0000019, GO:0030284=GO_REF:0000002, GO:0005634=GO_REF:0000029, GO:0038052=PMID:18722177, GO:0048146=GO_REF:0000019, GO:0043433=PMID:10816575, GO:0034056=PMID:17975005, GO:0005737=GO_REF:0000019, GO:0051091=PMID:10681512, GO:0045944=GO_REF:0000019, GO:0060523=GO_REF:0000019, GO:0030235=PMID:12389206, GO:0060527=GO_REF:0000019, GO:0006355=GO_REF:0000029, GO:0060745=GO_REF:0000019, GO:0008209=GO_REF:0000019, GO:0042981=GO_REF:0000019, GO:0003677=GO_REF:0000002, GO:0006351=GO_REF:0000038, GO:0043565=GO_REF:0000002, GO:0007165=PMID:10749889, GO:0016020=PMID:11960618, GO:0003682=GO_REF:0000019, GO:0016021=GO_REF:0000037, GO:0060749=GO_REF:0000019, GO:0008584=GO_REF:0000019, GO:0030520=PMID:3753802} Q9H2M1 Estrogen receptor alpha protein 20021106 {GO:0005515=IPI, GO:0010467=TAS, GO:0043627=IDA, GO:0003700=IEA, GO:0006367=TAS, GO:0008013=IPI, GO:0060750=IEA, GO:0003707=NAS, GO:0042802=IPI, GO:0002064=IEA, GO:0004879=IEA, GO:0005496=IEA, GO:0032355=IDA, GO:0043124=IDA, GO:0005794=IEA, GO:0071391=IEA, GO:0060687=IEA, GO:0001547=IEA, GO:0048386=IDA, GO:0008270=IEA, GO:0005654=TAS, GO:0019899=IPI, GO:0008134=IEA, GO:0060065=IEA, GO:0005886=IDA, GO:0060068=IEA, GO:0030284=IEA, GO:0005634=NAS, GO:0038052=IGI, GO:0048146=IEA, GO:0043433=IDA, GO:0034056=IDA, GO:0005737=IEA, GO:0051091=IDA, GO:0045944=IEA, GO:0060523=IEA, GO:0030235=NAS, GO:0060527=IEA, GO:0006355=NAS, GO:0060745=IEA, GO:0008209=IEA, GO:0042981=IEA, GO:0003677=IEA, GO:0006351=IEA, GO:0043565=IEA, GO:0007165=TAS, GO:0016020=NAS, GO:0003682=IEA, GO:0016021=IEA, GO:0060749=IEA, GO:0008584=IEA, GO:0030520=NAS} androgen metabolic process, antral ovarian follicle growth, cellular response to estrogen stimulus, epithelial cell development, epithelial cell proliferation involved in mammary gland duct elongation, gene expression, intracellular estrogen receptor signaling pathway, male gonad development, mammary gland alveolus development, mammary gland branching involved in pregnancy, negative regulation of I-kappaB kinase/NF-kappaB cascade, negative regulation of sequence-specific DNA binding transcription factor activity, positive regulation of fibroblast proliferation, positive regulation of retinoic acid receptor signaling pathway, positive regulation of sequence-specific DNA binding transcription factor activity, positive regulation of transcription from RNA polymerase II promoter, prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis, prostate epithelial cord elongation, regulation of apoptotic process, regulation of branching involved in prostate gland morphogenesis, regulation of transcription, DNA-dependent, response to estradiol stimulus, response to estrogen stimulus, signal transduction, transcription initiation from RNA polymerase II promoter, transcription, DNA-dependent, uterus development, vagina development Golgi apparatus, cytoplasm, integral to membrane, membrane, nucleoplasm, nucleus, plasma membrane DNA binding, beta-catenin binding, chromatin binding, enzyme binding, estrogen receptor activity, estrogen response element binding, estrogen-activated sequence-specific DNA binding RNA polymerase II transcription factor activity, identical protein binding, ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity, nitric-oxide synthase regulator activity, protein binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, steroid binding, steroid hormone receptor activity, transcription factor binding, zinc ion binding Human ESR2 GOC UniProtKB {GO:0005515=PMID:14764652, GO:0010467=Reactome:REACT_71, GO:0060065=GO_REF:0000019, GO:0030308=PMID:11181953, GO:0006367=Reactome:REACT_15525, GO:0003700=PMID:8769313, GO:0060068=GO_REF:0000019, GO:0007267=PMID:8769313, GO:0050680=GO_REF:0000019, GO:0003707=PMID:10749889, GO:0030284=PMID:11181953, GO:0005634=PMID:11181953, GO:0005739=PMID:15024130, GO:0001541=GO_REF:0000019, GO:0051091=PMID:10681512, GO:0004879=PMID:9671811, GO:0005496=PMID:11181953, GO:0048019=PMID:9671811, GO:0006355=PMID:11181953, GO:0043065=GO_REF:0000019, GO:0060743=GO_REF:0000019, GO:0003713=PMID:8769313, GO:0060740=GO_REF:0000019, GO:0060766=GO_REF:0000019, GO:0005576=PMID:9671811, GO:0003677=PMID:9636657, GO:0006351=GO_REF:0000038, GO:0043565=GO_REF:0000002, GO:0007165=PMID:8769313, GO:1900116=PMID:9671811, GO:0007420=GO_REF:0000019, GO:0005654=Reactome:REACT_19207, GO:0008270=GO_REF:0000002, GO:0001764=GO_REF:0000019, GO:0019899=PMID:12039952, GO:0030520=PMID:11181953} Q92731 Estrogen receptor beta protein 20130413 {GO:0005515=IPI, GO:0010467=TAS, GO:0060065=IEA, GO:0030308=NAS, GO:0006367=TAS, GO:0003700=TAS, GO:0060068=IEA, GO:0007267=TAS, GO:0050680=IEA, GO:0003707=TAS, GO:0030284=TAS, GO:0005634=TAS, GO:0005739=IDA, GO:0001541=IEA, GO:0051091=IDA, GO:0004879=NAS, GO:0005496=TAS, GO:0048019=NAS, GO:0006355=TAS, GO:0043065=IEA, GO:0060743=IEA, GO:0003713=TAS, GO:0060740=IEA, GO:0060766=IEA, GO:0005576=NAS, GO:0003677=TAS, GO:0006351=IEA, GO:0043565=IEA, GO:0007165=TAS, GO:1900116=NAS, GO:0007420=IEA, GO:0005654=TAS, GO:0008270=IEA, GO:0001764=IEA, GO:0019899=IPI, GO:0030520=TAS} brain development, cell-cell signaling, epithelial cell maturation involved in prostate gland development, extracellular negative regulation of signal transduction, gene expression, intracellular estrogen receptor signaling pathway, negative regulation of androgen receptor signaling pathway, negative regulation of cell growth, negative regulation of epithelial cell proliferation, neuron migration, ovarian follicle development, positive regulation of apoptotic process, positive regulation of sequence-specific DNA binding transcription factor activity, prostate gland epithelium morphogenesis, regulation of transcription, DNA-dependent, signal transduction, transcription initiation from RNA polymerase II promoter, transcription, DNA-dependent, uterus development, vagina development extracellular region, mitochondrion, nucleoplasm, nucleus DNA binding, enzyme binding, estrogen receptor activity, ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity, protein binding, receptor antagonist activity, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, steroid binding, steroid hormone receptor activity, transcription coactivator activity, zinc ion binding Human ESRP1 HPA UniProtKB {GO:0008380=GO_REF:0000037, GO:0006397=GO_REF:0000037, GO:0005886=GO_REF:0000052, GO:0000166=GO_REF:0000002, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0043484=PMID:19285943, GO:0003729=PMID:19285943, GO:0003676=GO_REF:0000002} Q6NXG1 Epithelial splicing regulatory protein 1 protein 20100326 {GO:0008380=IEA, GO:0006397=IEA, GO:0005886=IDA, GO:0000166=IEA, GO:0005730=IDA, GO:0005634=IDA, GO:0043484=IDA, GO:0003729=IDA, GO:0003676=IEA} RNA splicing, mRNA processing, regulation of RNA splicing nucleolus, nucleus, plasma membrane mRNA binding, nucleic acid binding, nucleotide binding Human ESRP2 HPA UniProtKB {GO:0005739=GO_REF:0000052, GO:0008380=GO_REF:0000037, GO:0006397=GO_REF:0000037, GO:0005813=GO_REF:0000052, GO:0005737=GO_REF:0000052, GO:0000166=GO_REF:0000002, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0043484=PMID:19285943, GO:0003729=PMID:19285943} Q9H6T0 Epithelial splicing regulatory protein 2 protein 20120912 {GO:0005739=IDA, GO:0008380=IEA, GO:0006397=IEA, GO:0005813=IDA, GO:0005737=IDA, GO:0000166=IEA, GO:0005730=IDA, GO:0005634=IDA, GO:0043484=IDA, GO:0003729=IDA} RNA splicing, mRNA processing, regulation of RNA splicing centrosome, cytoplasm, mitochondrion, nucleolus, nucleus mRNA binding, nucleotide binding Human ESRRA GOC UniProtKB {GO:0005515=PMID:16260778, GO:0010467=Reactome:REACT_71, GO:0006367=Reactome:REACT_15525, GO:0003700=GO_REF:0000002, GO:0051216=GO_REF:0000019, GO:0019904=PMID:11984006, GO:0003707=GO_REF:0000002, GO:0005634=PMID:9286700, GO:0045670=GO_REF:0000019, GO:0003677=PMID:9286700, GO:0006351=GO_REF:0000038, GO:0043565=GO_REF:0000002, GO:0045667=GO_REF:0000019, GO:0042127=GO_REF:0000019, GO:0045944=GO_REF:0000024, GO:0005654=Reactome:REACT_19207, GO:0008270=GO_REF:0000002, GO:0004879=PMID:9286700, GO:0030522=PMID:9286700, GO:0005496=GO_REF:0000002} P11474 Steroid hormone receptor ERR1 protein 20130413 {GO:0005515=IPI, GO:0010467=TAS, GO:0006367=TAS, GO:0003700=IEA, GO:0051216=IEA, GO:0019904=IPI, GO:0003707=IEA, GO:0005634=TAS, GO:0045670=IEA, GO:0003677=TAS, GO:0006351=IEA, GO:0043565=IEA, GO:0045667=IEA, GO:0042127=IEA, GO:0045944=ISS, GO:0005654=TAS, GO:0008270=IEA, GO:0004879=TAS, GO:0030522=TAS, GO:0005496=IEA} cartilage development, gene expression, intracellular receptor signaling pathway, positive regulation of transcription from RNA polymerase II promoter, regulation of cell proliferation, regulation of osteoblast differentiation, regulation of osteoclast differentiation, transcription initiation from RNA polymerase II promoter, transcription, DNA-dependent nucleoplasm, nucleus DNA binding, ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity, protein binding, protein domain specific binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, steroid binding, steroid hormone receptor activity, zinc ion binding Human ESRRB GOC UniProtKB {GO:0010467=Reactome:REACT_71, GO:0001831=GO_REF:0000019, GO:0006367=Reactome:REACT_15525, GO:0003700=GO_REF:0000002, GO:0001834=GO_REF:0000019, GO:0003713=GO_REF:0000024, GO:0003707=GO_REF:0000002, GO:0001892=PMID:19196830, GO:0005634=GO_REF:0000024, GO:0006351=GO_REF:0000038, GO:0043565=PMID:12654265, GO:0045944=GO_REF:0000024, GO:0019827=GO_REF:0000019, GO:0000980=GO_REF:0000024, GO:0008270=GO_REF:0000002, GO:0005654=Reactome:REACT_19207, GO:0004879=PMID:9344655, GO:0030522=PMID:9344655, GO:0005496=GO_REF:0000002, GO:0008134=GO_REF:0000024} O95718 Steroid hormone receptor ERR2 protein 20130413 {GO:0010467=TAS, GO:0001831=IEA, GO:0006367=TAS, GO:0003700=IEA, GO:0001834=IEA, GO:0003713=ISS, GO:0003707=IEA, GO:0001892=NAS, GO:0005634=ISS, GO:0006351=IEA, GO:0043565=IDA, GO:0045944=ISS, GO:0019827=IEA, GO:0000980=ISS, GO:0008270=IEA, GO:0005654=TAS, GO:0004879=TAS, GO:0030522=TAS, GO:0005496=IEA, GO:0008134=ISS} embryonic placenta development, gene expression, intracellular receptor signaling pathway, positive regulation of transcription from RNA polymerase II promoter, stem cell maintenance, transcription initiation from RNA polymerase II promoter, transcription, DNA-dependent, trophectodermal cell proliferation, trophectodermal cellular morphogenesis nucleoplasm, nucleus RNA polymerase II distal enhancer sequence-specific DNA binding, ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, steroid binding, steroid hormone receptor activity, transcription coactivator activity, transcription factor binding, zinc ion binding Human ESRRG Reactome UniProtKB {GO:0005515=PMID:10428842, GO:0010467=Reactome:REACT_71, GO:0003700=GO_REF:0000002, GO:0006367=Reactome:REACT_15525, GO:0003707=GO_REF:0000002, GO:0005634=GO_REF:0000038, GO:0050682=GO_REF:0000024, GO:0003708=GO_REF:0000002, GO:0006351=GO_REF:0000038, GO:0043565=GO_REF:0000002, GO:0008270=GO_REF:0000002, GO:0005654=Reactome:REACT_19207, GO:0045893=GO_REF:0000024, GO:0005496=GO_REF:0000002} P62508 Estrogen-related receptor gamma protein 20130301 {GO:0005515=IPI, GO:0010467=TAS, GO:0003700=IEA, GO:0006367=TAS, GO:0003707=IEA, GO:0005634=IEA, GO:0050682=ISS, GO:0003708=IEA, GO:0006351=IEA, GO:0043565=IEA, GO:0008270=IEA, GO:0005654=TAS, GO:0045893=ISS, GO:0005496=IEA} gene expression, positive regulation of transcription, DNA-dependent, transcription initiation from RNA polymerase II promoter, transcription, DNA-dependent nucleoplasm, nucleus AF-2 domain binding, protein binding, retinoic acid receptor activity, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, steroid binding, steroid hormone receptor activity, zinc ion binding Human ESX1 UniProtKB UniProtKB {GO:0043565=PMID:15897875, GO:0005737=PMID:15235584, GO:0003700=GO_REF:0000002, GO:0051726=PMID:15235584, GO:0005634=PMID:15235584, GO:0045892=PMID:15897875, GO:0006351=GO_REF:0000037} Q8N693 Homeobox protein ESX1 protein 20090924 {GO:0043565=IDA, GO:0005737=IDA, GO:0003700=IEA, GO:0051726=IDA, GO:0005634=IDA, GO:0045892=IDA, GO:0006351=IEA} negative regulation of transcription, DNA-dependent, regulation of cell cycle, transcription, DNA-dependent cytoplasm, nucleus sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity Human ESYT1 UniProtKB UniProtKB {GO:0016021=GO_REF:0000037} Q9BSJ8 Extended synaptotagmin-1 protein 20130413 {GO:0016021=IEA} integral to membrane Human UniProtKB-KW:KW-0812 ESYT2 UniProtKB UniProtKB {GO:0005886=GO_REF:0000039, GO:0016021=GO_REF:0000037} A0FGR8 Extended synaptotagmin-2 protein 20130413 {GO:0005886=IEA, GO:0016021=IEA} integral to membrane, plasma membrane Human UniProtKB-SubCell:SL-0039 ETAA1 HPA UniProtKB {GO:0005737=GO_REF:0000052, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052} Q9NY74 Ewing's tumor-associated antigen 1 protein 20101115 {GO:0005737=IDA, GO:0005730=IDA, GO:0005634=IDA} cytoplasm, nucleolus, nucleus Human ETF1 InterPro UniProtKB {GO:0005515=PMID:9712840, GO:0010467=Reactome:REACT_71, GO:0016070=Reactome:REACT_21257, GO:0016071=Reactome:REACT_20605, GO:0003723=PMID:7990965, GO:0006449=PMID:7990965, GO:0006415=Reactome:REACT_1986, GO:0003747=PMID:15326224, GO:0006412=Reactome:REACT_1014, GO:0005829=Reactome:REACT_75917, GO:0005737=GO_REF:0000002, GO:0016149=GO_REF:0000002, GO:0000184=Reactome:REACT_75886, GO:0006479=PMID:18539146, GO:0043022=PMID:12867083, GO:0008079=PMID:10413110, GO:0044267=Reactome:REACT_17015} Q96CG1 Eukaryotic translation termination factor 1, isoform CRA_b protein 20130413 {GO:0005515=IPI, GO:0010467=TAS, GO:0016070=TAS, GO:0016071=TAS, GO:0003723=TAS, GO:0006449=TAS, GO:0006415=TAS, GO:0003747=TAS, GO:0006412=TAS, GO:0005829=TAS, GO:0005737=IEA, GO:0016149=IEA, GO:0000184=TAS, GO:0006479=IDA, GO:0043022=TAS, GO:0008079=TAS, GO:0044267=TAS} RNA metabolic process, cellular protein metabolic process, gene expression, mRNA metabolic process, nuclear-transcribed mRNA catabolic process, nonsense-mediated decay, protein methylation, regulation of translational termination, translation, translational termination cytoplasm, cytosol RNA binding, protein binding, ribosome binding, translation release factor activity, translation release factor activity, codon specific, translation termination factor activity Human InterPro:IPR004403 ETFA Reactome UniProtKB {GO:0022904=Reactome:REACT_22393, GO:0005739=PMID:3170610, GO:0005759=Reactome:REACT_6169, GO:0050660=PMID:10423253, GO:0016491=PMID:10423253, GO:0009055=PMID:10423253, GO:0044281=Reactome:REACT_111217} P13804 Electron transfer flavoprotein subunit alpha, mitochondrial protein 20051125 {GO:0022904=TAS, GO:0005739=TAS, GO:0005759=TAS, GO:0050660=IDA, GO:0016491=IDA, GO:0009055=IDA, GO:0044281=TAS} respiratory electron transport chain, small molecule metabolic process mitochondrial matrix, mitochondrion electron carrier activity, flavin adenine dinucleotide binding, oxidoreductase activity Human ETFB HPA UniProtKB {GO:0005739=GO_REF:0000052, GO:0022904=Reactome:REACT_22393, GO:0005759=Reactome:REACT_6169, GO:0009055=GO_REF:0000002, GO:0044281=Reactome:REACT_111217, GO:0043231=GO_REF:0000052} P38117 Electron transfer flavoprotein subunit beta protein 20100326 {GO:0005739=IDA, GO:0022904=TAS, GO:0005759=TAS, GO:0009055=IEA, GO:0044281=TAS, GO:0043231=IDA} respiratory electron transport chain, small molecule metabolic process intracellular membrane-bounded organelle, mitochondrial matrix, mitochondrion electron carrier activity Human ETFDH BHF-UCL UniProtKB {GO:0048039=PMID:14640977, GO:0051539=PMID:18037314, GO:0048038=PMID:14640977, GO:0031966=PMID:12049629, GO:0051536=GO_REF:0000002, GO:0043783=GO_REF:0000024, GO:0050660=PMID:17050691, GO:0005743=GO_REF:0000019, GO:0009055=PMID:12049629, GO:0044281=Reactome:REACT_111217, GO:0033539=PMID:17412732, GO:0046872=GO_REF:0000037, GO:0022904=Reactome:REACT_22393, GO:0004174=PMID:12049629, GO:0005759=Reactome:REACT_6169, GO:0016491=PMID:14640977, GO:0031305=PMID:8306995, GO:0022900=PMID:12049629, GO:0006979=GO_REF:0000024} Q16134 Electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial protein 20090907 {GO:0048039=IDA, GO:0051539=IDA, GO:0048038=IDA, GO:0031966=IDA, GO:0051536=IEA, GO:0043783=ISS, GO:0050660=ISS, GO:0005743=IEA, GO:0009055=IDA, GO:0044281=TAS, GO:0033539=IMP, GO:0046872=IEA, GO:0022904=TAS, GO:0004174=IDA, GO:0005759=TAS, GO:0016491=IDA, GO:0031305=IDA, GO:0022900=IDA, GO:0006979=ISS} electron transport chain, fatty acid beta-oxidation using acyl-CoA dehydrogenase, respiratory electron transport chain, response to oxidative stress, small molecule metabolic process integral to mitochondrial inner membrane, mitochondrial inner membrane, mitochondrial matrix, mitochondrial membrane 4 iron, 4 sulfur cluster binding, electron carrier activity, electron-transferring-flavoprotein dehydrogenase activity, flavin adenine dinucleotide binding, iron-sulfur cluster binding, metal ion binding, oxidoreductase activity, oxidoreductase activity, oxidizing metal ions with flavin as acceptor, quinone binding, ubiquinone binding Human ETHE1 HPA UniProtKB {GO:0050313=Reactome:REACT_115730, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0044281=Reactome:REACT_111217, GO:0046872=GO_REF:0000037, GO:0005739=GO_REF:0000052, GO:0034641=Reactome:REACT_13, GO:0005737=GO_REF:0000054, GO:0000096=Reactome:REACT_115639, GO:0016787=GO_REF:0000037, GO:0000098=Reactome:REACT_115654, GO:0005759=Reactome:REACT_115730, GO:0070221=Reactome:REACT_116010} O95571 Protein ETHE1, mitochondrial protein 20111111 {GO:0050313=TAS, GO:0005730=IDA, GO:0005634=IDA, GO:0044281=TAS, GO:0046872=IEA, GO:0005739=IDA, GO:0034641=TAS, GO:0005737=IDA, GO:0000096=TAS, GO:0016787=IEA, GO:0000098=TAS, GO:0005759=TAS, GO:0070221=TAS} cellular nitrogen compound metabolic process, small molecule metabolic process, sulfide oxidation, using sulfide:quinone oxidoreductase, sulfur amino acid catabolic process, sulfur amino acid metabolic process cytoplasm, mitochondrial matrix, mitochondrion, nucleolus, nucleus hydrolase activity, metal ion binding, sulfur dioxygenase activity Human ETNK1 Reactome UniProtKB {GO:0004305=PMID:11044454, GO:0006646=Reactome:REACT_120919, GO:0005737=GO_REF:0000029, GO:0016301=GO_REF:0000002, GO:0044281=Reactome:REACT_111217, GO:0006644=Reactome:REACT_120870, GO:0005524=GO_REF:0000037, GO:0005829=Reactome:REACT_121273, GO:0046474=Reactome:REACT_121401} Q9HBU6 Ethanolamine kinase 1 protein 20130301 {GO:0004305=IDA, GO:0006646=TAS, GO:0005737=NAS, GO:0016301=IEA, GO:0044281=TAS, GO:0006644=TAS, GO:0005524=IEA, GO:0005829=TAS, GO:0046474=TAS} glycerophospholipid biosynthetic process, phosphatidylethanolamine biosynthetic process, phospholipid metabolic process, small molecule metabolic process cytoplasm, cytosol ATP binding, ethanolamine kinase activity, kinase activity Human ETNK2 Reactome UniProtKB {GO:0004305=GO_REF:0000003, GO:0006646=Reactome:REACT_120919, GO:0044281=Reactome:REACT_111217, GO:0001890=GO_REF:0000019, GO:0005575=GO_REF:0000015, GO:0009791=GO_REF:0000019, GO:0001701=GO_REF:0000019, GO:0005524=GO_REF:0000037, GO:0005829=Reactome:REACT_121273, GO:0008150=GO_REF:0000015, GO:0035264=GO_REF:0000019, GO:0016301=GO_REF:0000002, GO:0006644=Reactome:REACT_120870, GO:0046474=Reactome:REACT_121401} Q9NVF9 Ethanolamine kinase 2 protein 20130301 {GO:0004305=IEA, GO:0006646=TAS, GO:0044281=TAS, GO:0001890=IEA, GO:0005575=ND, GO:0009791=IEA, GO:0001701=IEA, GO:0005524=IEA, GO:0005829=TAS, GO:0008150=ND, GO:0035264=IEA, GO:0016301=IEA, GO:0006644=TAS, GO:0046474=TAS} biological_process, glycerophospholipid biosynthetic process, in utero embryonic development, multicellular organism growth, phosphatidylethanolamine biosynthetic process, phospholipid metabolic process, placenta development, post-embryonic development, small molecule metabolic process cellular_component, cytosol ATP binding, ethanolamine kinase activity, kinase activity Human ETS1 InterPro UniProtKB {GO:0005515=PMID:11909962, GO:0008284=GO_REF:0000019, GO:0003700=PMID:11909962, GO:0008285=PMID:2187191, GO:0070301=GO_REF:0000019, GO:0021983=GO_REF:0000019, GO:0005634=GO_REF:0000002, GO:0060206=GO_REF:0000019, GO:0010715=GO_REF:0000019, GO:0005737=GO_REF:0000039, GO:0006955=PMID:2187191, GO:0030578=PMID:11909962, GO:0048870=PMID:15247905, GO:0045944=PMID:15247905, GO:0032355=GO_REF:0000019, GO:0070555=GO_REF:0000019, GO:0005667=GO_REF:0000019, GO:0001666=GO_REF:0000019, GO:0007565=GO_REF:0000019, GO:0060055=GO_REF:0000019, GO:0045765=PMID:15592518, GO:0021854=GO_REF:0000019, GO:0003677=GO_REF:0000024, GO:0045766=GO_REF:0000019, GO:0006351=GO_REF:0000037, GO:0009612=GO_REF:0000019, GO:0043565=GO_REF:0000002, GO:0010595=PMID:15592518, GO:0045648=PMID:8620536, GO:0034616=GO_REF:0000019, GO:0045893=PMID:11909962, GO:0051272=PMID:15247905, GO:0008134=PMID:10698492} Q96AC5 Protein C-ets-1 protein 20130413 {GO:0005515=IPI, GO:0008284=IEA, GO:0003700=IDA, GO:0008285=TAS, GO:0070301=IEA, GO:0021983=IEA, GO:0005634=IEA, GO:0060206=IEA, GO:0010715=IEA, GO:0005737=IEA, GO:0006955=TAS, GO:0030578=IDA, GO:0048870=IMP, GO:0045944=IDA, GO:0032355=IEA, GO:0070555=IEA, GO:0005667=IEA, GO:0001666=IEA, GO:0007565=IEA, GO:0060055=IEA, GO:0045765=IMP, GO:0021854=IEA, GO:0003677=ISS, GO:0045766=IEA, GO:0006351=IEA, GO:0009612=IEA, GO:0043565=IEA, GO:0010595=IMP, GO:0045648=IDA, GO:0034616=IEA, GO:0045893=IDA, GO:0051272=IMP, GO:0008134=NAS} PML body organization, angiogenesis involved in wound healing, cell motility, cellular response to hydrogen peroxide, estrous cycle phase, female pregnancy, hypothalamus development, immune response, negative regulation of cell proliferation, pituitary gland development, positive regulation of angiogenesis, positive regulation of cell proliferation, positive regulation of cellular component movement, positive regulation of endothelial cell migration, positive regulation of erythrocyte differentiation, positive regulation of transcription from RNA polymerase II promoter, positive regulation of transcription, DNA-dependent, regulation of angiogenesis, regulation of extracellular matrix disassembly, response to estradiol stimulus, response to hypoxia, response to interleukin-1, response to laminar fluid shear stress, response to mechanical stimulus, transcription, DNA-dependent cytoplasm, nucleus, transcription factor complex DNA binding, protein binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, transcription factor binding Human InterPro:IPR003118 ETS2 BHF-UCL UniProtKB {GO:0005515=PMID:11909962, GO:0001501=PMID:8596630, GO:0003700=PMID:11909962, GO:0000977=GO_REF:0000019, GO:0045944=GO_REF:0000019, GO:0005634=PMID:16780588, GO:0035259=GO_REF:0000019, GO:0045893=PMID:11909962, GO:0003677=PMID:10918595} P15036 Protein C-ets-2 protein 20081024 {GO:0005515=IPI, GO:0001501=TAS, GO:0003700=IDA, GO:0000977=IEA, GO:0045944=IEA, GO:0005634=IDA, GO:0035259=IEA, GO:0045893=IDA, GO:0003677=TAS} positive regulation of transcription from RNA polymerase II promoter, positive regulation of transcription, DNA-dependent, skeletal system development nucleus DNA binding, RNA polymerase II regulatory region sequence-specific DNA binding, glucocorticoid receptor binding, protein binding, sequence-specific DNA binding transcription factor activity Human ETV1 BHF-UCL UniProtKB {GO:0005515=PMID:21575865, GO:0043565=GO_REF:0000002, GO:0007517=GO_REF:0000019, GO:0003700=GO_REF:0000002, GO:0006366=PMID:7700648, GO:0007411=GO_REF:0000019, GO:0048935=PMID:20096094, GO:0005634=GO_REF:0000039, GO:0007638=GO_REF:0000019, GO:0045893=GO_REF:0000019} P50549 ETS translocation variant 1 protein 20110708 {GO:0005515=IPI, GO:0043565=IEA, GO:0007517=IEA, GO:0003700=IEA, GO:0006366=TAS, GO:0007411=IEA, GO:0048935=TAS, GO:0005634=IEA, GO:0007638=IEA, GO:0045893=IEA} axon guidance, mechanosensory behavior, muscle organ development, peripheral nervous system neuron development, positive regulation of transcription, DNA-dependent, transcription from RNA polymerase II promoter nucleus protein binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity Human ETV2 UniProtKB UniProtKB {GO:0003700=GO_REF:0000002, GO:2000382=GO_REF:0000019, GO:0001824=GO_REF:0000019, GO:0048514=GO_REF:0000019, GO:0006915=GO_REF:0000019, GO:0005634=GO_REF:0000038, GO:0001890=GO_REF:0000019, GO:0043565=GO_REF:0000002, GO:0007219=GO_REF:0000019, GO:0045944=GO_REF:0000019, GO:0030218=GO_REF:0000019, GO:0060803=GO_REF:0000019, GO:0016055=GO_REF:0000019, GO:0045603=GO_REF:0000019} Q3KNT2 ETS translocation variant 2 protein 20130413 {GO:0003700=IEA, GO:2000382=IEA, GO:0001824=IEA, GO:0048514=IEA, GO:0006915=IEA, GO:0005634=IEA, GO:0001890=IEA, GO:0043565=IEA, GO:0007219=IEA, GO:0045944=IEA, GO:0030218=IEA, GO:0060803=IEA, GO:0016055=IEA, GO:0045603=IEA} BMP signaling pathway involved in mesodermal cell fate specification, Notch signaling pathway, Wnt receptor signaling pathway, apoptotic process, blastocyst development, blood vessel morphogenesis, erythrocyte differentiation, placenta development, positive regulation of endothelial cell differentiation, positive regulation of mesoderm development, positive regulation of transcription from RNA polymerase II promoter nucleus sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity Human UniProtKB-KW:KW-0539 ETV3 UniProtKB UniProtKB {GO:0043565=GO_REF:0000002, GO:0003674=GO_REF:0000015, GO:0008150=GO_REF:0000015, GO:0003700=GO_REF:0000002, GO:0017053=GO_REF:0000019, GO:0005634=GO_REF:0000029, GO:0000122=GO_REF:0000019, GO:0006351=GO_REF:0000037} P41162 ETS translocation variant 3 protein 20061026 {GO:0043565=IEA, GO:0003674=ND, GO:0008150=ND, GO:0003700=IEA, GO:0017053=IEA, GO:0005634=NAS, GO:0000122=IEA, GO:0006351=IEA} biological_process, negative regulation of transcription from RNA polymerase II promoter, transcription, DNA-dependent nucleus, transcriptional repressor complex molecular_function, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity Human ETV4 HPA UniProtKB {GO:0048863=GO_REF:0000019, GO:0043565=GO_REF:0000002, GO:0006355=GO_REF:0000029, GO:0008045=GO_REF:0000019, GO:0003700=GO_REF:0000002, GO:0060762=GO_REF:0000019, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000029, GO:0045893=GO_REF:0000029, GO:0033600=GO_REF:0000019, GO:0060444=GO_REF:0000019, GO:0006351=GO_REF:0000037} P43268 ETS translocation variant 4 protein 20080818 {GO:0048863=IEA, GO:0043565=IEA, GO:0006355=NAS, GO:0008045=IEA, GO:0003700=IEA, GO:0060762=IEA, GO:0005730=IDA, GO:0005634=NAS, GO:0045893=NAS, GO:0033600=IEA, GO:0060444=IEA, GO:0006351=IEA} branching involved in mammary gland duct morphogenesis, motor neuron axon guidance, negative regulation of mammary gland epithelial cell proliferation, positive regulation of transcription, DNA-dependent, regulation of branching involved in mammary gland duct morphogenesis, regulation of transcription, DNA-dependent, stem cell differentiation, transcription, DNA-dependent nucleolus, nucleus sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity Human ETV5 PINC UniProtKB {GO:0003700=GO_REF:0000002, GO:0044212=PMID:19443906, GO:0060762=GO_REF:0000019, GO:0005634=PMID:19443906, GO:0007274=GO_REF:0000019, GO:0048133=GO_REF:0000019, GO:0060252=GO_REF:0000019, GO:0003677=PMID:8152800, GO:0043565=GO_REF:0000002, GO:0045666=GO_REF:0000019, GO:0050807=GO_REF:0000019, GO:0007610=GO_REF:0000019, GO:0034599=PMID:19443906, GO:0045893=GO_REF:0000019, GO:0071340=GO_REF:0000019} P41161 ETS translocation variant 5 protein 20030904 {GO:0003700=IEA, GO:0044212=IDA, GO:0060762=IEA, GO:0005634=IDA, GO:0007274=IEA, GO:0048133=IEA, GO:0060252=IEA, GO:0003677=TAS, GO:0043565=IEA, GO:0045666=IEA, GO:0050807=IEA, GO:0007610=IEA, GO:0034599=IDA, GO:0045893=IEA, GO:0071340=IEA} behavior, cellular response to oxidative stress, male germ-line stem cell division, neuromuscular synaptic transmission, positive regulation of glial cell proliferation, positive regulation of neuron differentiation, positive regulation of transcription, DNA-dependent, regulation of branching involved in mammary gland duct morphogenesis, regulation of synapse organization, skeletal muscle acetylcholine-gated channel clustering nucleus DNA binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, transcription regulatory region DNA binding Human ETV6 IntAct UniProtKB {GO:0005515=PMID:12590135, GO:0043565=GO_REF:0000002, GO:0003700=GO_REF:0000019, GO:0019904=PMID:12588862, GO:0005634=GO_REF:0000039, GO:0030154=GO_REF:0000019, GO:0006351=GO_REF:0000037} P41212 Transcription factor ETV6 protein 20130415 {GO:0005515=IPI, GO:0043565=IEA, GO:0003700=IEA, GO:0019904=IPI, GO:0005634=IEA, GO:0030154=IEA, GO:0006351=IEA} cell differentiation, transcription, DNA-dependent nucleus protein binding, protein domain specific binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity Human UniProtKB:Q9UKV0-3 ETV7 HPA UniProtKB {GO:0005515=PMID:12588862, GO:0043565=GO_REF:0000002, GO:0003700=GO_REF:0000002, GO:0006366=PMID:10828014, GO:0005730=GO_REF:0000052, GO:0009887=PMID:10828014, GO:0005634=GO_REF:0000052} Q9Y603 Transcription factor ETV7 protein 20101115 {GO:0005515=IPI, GO:0043565=IEA, GO:0003700=IEA, GO:0006366=TAS, GO:0005730=IDA, GO:0009887=TAS, GO:0005634=IDA} organ morphogenesis, transcription from RNA polymerase II promoter nucleolus, nucleus protein binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity NOT Human EVC2 UniProtKB UniProtKB {GO:0005929=GO_REF:0000024, GO:0060170=GO_REF:0000039, GO:0005737=GO_REF:0000037, GO:0005634=GO_REF:0000024, GO:0005932=GO_REF:0000039, GO:0016021=GO_REF:0000037, GO:0007224=GO_REF:0000024} Q86UK5 Limbin protein 20111004 {GO:0005929=ISS, GO:0060170=IEA, GO:0005737=IEA, GO:0005634=ISS, GO:0005932=IEA, GO:0016021=IEA, GO:0007224=ISS} smoothened signaling pathway cilium, cilium membrane, cytoplasm, integral to membrane, microtubule basal body, nucleus Human UniProtKB:Q8K1G2 EVI2A UniProtKB UniProtKB {GO:0016021=GO_REF:0000037, GO:0004888=PMID:2117566} P22794 Protein EVI2A protein 20041028 {GO:0016021=IEA, GO:0004888=NAS} integral to membrane transmembrane signaling receptor activity Human EVI5 IntAct UniProtKB {GO:0005515=PMID:16439210, GO:0005622=GO_REF:0000002, GO:0007049=GO_REF:0000037, GO:0005737=GO_REF:0000037, GO:0005815=GO_REF:0000039, GO:0008283=PMID:9618176, GO:0005819=GO_REF:0000039, GO:0007275=PMID:9618176, GO:0005634=GO_REF:0000039, GO:0005097=GO_REF:0000002, GO:0051301=GO_REF:0000037} O60447 Ecotropic viral integration site 5 protein homolog protein 20130415 {GO:0005515=IPI, GO:0005622=IEA, GO:0007049=IEA, GO:0005737=IEA, GO:0005815=IEA, GO:0008283=TAS, GO:0005819=IEA, GO:0007275=TAS, GO:0005634=IEA, GO:0005097=IEA, GO:0051301=IEA} cell cycle, cell division, cell proliferation, multicellular organismal development cytoplasm, intracellular, microtubule organizing center, nucleus, spindle Rab GTPase activator activity, protein binding Human UniProtKB:Q9UKT4 EVI5L IntAct UniProtKB {GO:0005515=PMID:19060904, GO:0005622=GO_REF:0000002, GO:0005097=GO_REF:0000002} Q96CN4 EVI5-like protein protein 20130415 {GO:0005515=IPI, GO:0005622=IEA, GO:0005097=IEA} intracellular Rab GTPase activator activity, protein binding Human UniProtKB:Q6ZVK8 EVL Reactome UniProtKB {GO:0005515=PMID:10993894, GO:0017124=GO_REF:0000024, GO:0003779=GO_REF:0000037, GO:0030027=GO_REF:0000024, GO:0005829=Reactome:REACT_19293, GO:0007399=PMID:10993894, GO:0005737=GO_REF:0000024, GO:0007411=Reactome:REACT_18266, GO:0051289=GO_REF:0000002, GO:0008154=GO_REF:0000024, GO:0009887=PMID:10993894, GO:0007015=PMID:9268706, GO:0005856=GO_REF:0000039, GO:0005522=GO_REF:0000024, GO:0005925=GO_REF:0000024, GO:0007166=PMID:10993894} Q9UI08 Ena/VASP-like protein protein 20130301 {GO:0005515=IPI, GO:0017124=ISS, GO:0003779=IEA, GO:0030027=ISS, GO:0005829=TAS, GO:0007399=NAS, GO:0005737=ISS, GO:0007411=TAS, GO:0051289=IEA, GO:0008154=ISS, GO:0009887=NAS, GO:0007015=TAS, GO:0005856=IEA, GO:0005522=ISS, GO:0005925=ISS, GO:0007166=NAS} actin filament organization, actin polymerization or depolymerization, axon guidance, cell surface receptor signaling pathway, nervous system development, organ morphogenesis, protein homotetramerization cytoplasm, cytoskeleton, cytosol, focal adhesion, lamellipodium SH3 domain binding, actin binding, profilin binding, protein binding Human EVPL PINC UniProtKB {GO:0030057=GO_REF:0000039, GO:0005737=GO_REF:0000037, GO:0018149=PMID:10908733, GO:0008544=PMID:8707850, GO:0030216=PMID:10908733, GO:0005198=PMID:10908733, GO:0031424=GO_REF:0000037, GO:0030674=PMID:10908733, GO:0005856=GO_REF:0000002, GO:0001533=PMID:10908733} Q92817 Envoplakin protein 20030904 {GO:0030057=IEA, GO:0005737=IEA, GO:0018149=IDA, GO:0008544=TAS, GO:0030216=IDA, GO:0005198=IDA, GO:0031424=IEA, GO:0030674=IDA, GO:0005856=IEA, GO:0001533=IDA} epidermis development, keratinization, keratinocyte differentiation, peptide cross-linking cornified envelope, cytoplasm, cytoskeleton, desmosome protein binding, bridging, structural molecule activity Human EVX1 UniProtKB UniProtKB {GO:0043565=GO_REF:0000002, GO:0003700=GO_REF:0000002, GO:0045944=GO_REF:0000019, GO:0005634=GO_REF:0000039, GO:0009792=GO_REF:0000019, GO:0021913=GO_REF:0000019} P49640 Homeobox even-skipped homolog protein 1 protein 20130413 {GO:0043565=IEA, GO:0003700=IEA, GO:0045944=IEA, GO:0005634=IEA, GO:0009792=IEA, GO:0021913=IEA} embryo development ending in birth or egg hatching, positive regulation of transcription from RNA polymerase II promoter, regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification nucleus sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity Human UniProtKB-SubCell:SL-0191 EWSR1 IntAct UniProtKB {GO:0005515=PMID:18347058, GO:0005622=GO_REF:0000002, GO:0005516=GO_REF:0000037, GO:0005737=GO_REF:0000039, GO:0006355=GO_REF:0000037, GO:0005886=GO_REF:0000039, GO:0000166=GO_REF:0000002, GO:0003723=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0006351=GO_REF:0000037} Q01844 RNA-binding protein EWS protein 20130415 {GO:0005515=IPI, GO:0005622=IEA, GO:0005516=IEA, GO:0005737=IEA, GO:0006355=IEA, GO:0005886=IEA, GO:0000166=IEA, GO:0003723=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003676=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent cytoplasm, intracellular, nucleus, plasma membrane RNA binding, calmodulin binding, nucleic acid binding, nucleotide binding, protein binding, zinc ion binding Human UniProtKB:Q9NS23-2 EXD1 InterPro UniProtKB {GO:0008408=GO_REF:0000002, GO:0003676=GO_REF:0000002} Q8NHP7 Exonuclease 3'-5' domain-containing protein 1 protein 20130413 {GO:0008408=IEA, GO:0003676=IEA} 3'-5' exonuclease activity, nucleic acid binding Human InterPro:IPR002562 EXD2 InterPro UniProtKB {GO:0008408=GO_REF:0000002, GO:0003676=GO_REF:0000002} Q9NVH0 Exonuclease 3'-5' domain-containing protein 2 protein 20130413 {GO:0008408=IEA, GO:0003676=IEA} 3'-5' exonuclease activity, nucleic acid binding Human InterPro:IPR002562 EXD3 IntAct UniProtKB {GO:0005515=PMID:19060904, GO:0008408=GO_REF:0000002, GO:0003676=GO_REF:0000002} Q9NX53 Probable exonuclease mut-7 homolog, isoform 5 protein 20130415 {GO:0005515=IPI, GO:0008408=IEA, GO:0003676=IEA} 3'-5' exonuclease activity, nucleic acid binding, protein binding Human UniProtKB:Q15038 EXO1 PINC UniProtKB {GO:0005515=PMID:15886194, GO:0035312=PMID:10608837, GO:0008409=PMID:9685493, GO:0045190=GO_REF:0000019, GO:0005634=PMID:14676842, GO:0006310=PMID:10364235, GO:0051908=PMID:11842105, GO:0016446=GO_REF:0000019, GO:0003677=PMID:11842105, GO:0046872=GO_REF:0000037, GO:0004527=PMID:9788596, GO:0004518=GO_REF:0000002, GO:0006281=PMID:10364235, GO:0007126=GO_REF:0000037, GO:0045145=PMID:10608837, GO:0004523=PMID:10364235, GO:0043566=GO_REF:0000019, GO:0048256=PMID:11842105, GO:0006298=PMID:14636568, GO:0002455=GO_REF:0000019} Q9UQ84 Exonuclease 1 protein 20061106 {GO:0005515=IPI, GO:0035312=IDA, GO:0008409=ISS, GO:0045190=IEA, GO:0005634=IDA, GO:0006310=IGI, GO:0051908=IDA, GO:0016446=IEA, GO:0003677=IDA, GO:0046872=IEA, GO:0004527=TAS, GO:0004518=IEA, GO:0006281=TAS, GO:0007126=IEA, GO:0045145=IDA, GO:0004523=TAS, GO:0043566=IEA, GO:0048256=IDA, GO:0006298=IDA, GO:0002455=IEA} DNA recombination, DNA repair, humoral immune response mediated by circulating immunoglobulin, isotype switching, meiosis, mismatch repair, somatic hypermutation of immunoglobulin genes nucleus 5'-3' exodeoxyribonuclease activity, 5'-3' exonuclease activity, DNA binding, double-stranded DNA specific 5'-3' exodeoxyribonuclease activity, exonuclease activity, flap endonuclease activity, metal ion binding, nuclease activity, protein binding, ribonuclease H activity, single-stranded DNA specific 5'-3' exodeoxyribonuclease activity, structure-specific DNA binding Human EXOC1 Reactome UniProtKB {GO:0000145=PMID:11406615, GO:0005886=Reactome:REACT_15394, GO:0006887=PMID:11406615, GO:0015031=GO_REF:0000037, GO:0044267=Reactome:REACT_17015, GO:0016044=Reactome:REACT_11123} Q9NV70 Exocyst complex component 1 protein 20130301 {GO:0000145=NAS, GO:0005886=TAS, GO:0006887=NAS, GO:0015031=IEA, GO:0044267=TAS, GO:0016044=TAS} cellular membrane organization, cellular protein metabolic process, exocytosis, protein transport exocyst, plasma membrane Human EXOC2 Reactome UniProtKB {GO:0005515=PMID:19166349, GO:0047485=GO_REF:0000019, GO:0005886=Reactome:REACT_15394, GO:0015031=GO_REF:0000037, GO:0006887=GO_REF:0000037, GO:0044267=Reactome:REACT_17015, GO:0017160=GO_REF:0000019, GO:0016044=Reactome:REACT_11123} Q96KP1 Exocyst complex component 2 protein 20130301 {GO:0005515=IPI, GO:0047485=IEA, GO:0005886=TAS, GO:0015031=IEA, GO:0006887=IEA, GO:0044267=TAS, GO:0017160=IEA, GO:0016044=TAS} cellular membrane organization, cellular protein metabolic process, exocytosis, protein transport plasma membrane Ral GTPase binding, protein N-terminus binding, protein binding Human EXOC3 Reactome UniProtKB {GO:0005515=PMID:18329369, GO:0000145=GO_REF:0000002, GO:0015031=GO_REF:0000037, GO:0006887=GO_REF:0000037, GO:0044267=Reactome:REACT_17015, GO:0016044=Reactome:REACT_11123, GO:0030667=Reactome:REACT_15394} O60645 Exocyst complex component 3 protein 20130301 {GO:0005515=IPI, GO:0000145=IEA, GO:0015031=IEA, GO:0006887=IEA, GO:0044267=TAS, GO:0016044=TAS, GO:0030667=TAS} cellular membrane organization, cellular protein metabolic process, exocytosis, protein transport exocyst, secretory granule membrane protein binding Human EXOC4 LIFEdb UniProtKB {GO:0005737=GO_REF:0000054, GO:0047485=PMID:18480549, GO:0000145=GO_REF:0000002, GO:0005886=Reactome:REACT_15394, GO:0032584=GO_REF:0000019, GO:0015031=GO_REF:0000037, GO:0044267=Reactome:REACT_17015, GO:0016044=Reactome:REACT_11123, GO:0035748=GO_REF:0000019, GO:0006904=GO_REF:0000002} Q96A65 Exocyst complex component 4 protein 20100607 {GO:0005737=IDA, GO:0047485=IPI, GO:0000145=IEA, GO:0005886=TAS, GO:0032584=IEA, GO:0015031=IEA, GO:0044267=TAS, GO:0016044=TAS, GO:0035748=IEA, GO:0006904=IEA} cellular membrane organization, cellular protein metabolic process, protein transport, vesicle docking involved in exocytosis cytoplasm, exocyst, growth cone membrane, myelin sheath abaxonal region, plasma membrane protein N-terminus binding Human EXOC5 Reactome UniProtKB {GO:0005737=PMID:9119050, GO:0047485=GO_REF:0000019, GO:0006892=PMID:9119050, GO:0015031=GO_REF:0000037, GO:0006887=GO_REF:0000037, GO:0044267=Reactome:REACT_17015, GO:0016044=Reactome:REACT_11123, GO:0048278=GO_REF:0000002, GO:0005829=Reactome:REACT_15394} O00471 Exocyst complex component 5 protein 20130301 {GO:0005737=TAS, GO:0047485=IEA, GO:0006892=TAS, GO:0015031=IEA, GO:0006887=IEA, GO:0044267=TAS, GO:0016044=TAS, GO:0048278=IEA, GO:0005829=TAS} cellular membrane organization, cellular protein metabolic process, exocytosis, post-Golgi vesicle-mediated transport, protein transport, vesicle docking cytoplasm, cytosol protein N-terminus binding Human EXOC6 Reactome UniProtKB {GO:0000145=GO_REF:0000002, GO:0005886=Reactome:REACT_15394, GO:0030218=GO_REF:0000019, GO:0015031=GO_REF:0000037, GO:0044267=Reactome:REACT_17015, GO:0016044=Reactome:REACT_11123, GO:0006904=GO_REF:0000002} Q8TAG9 Exocyst complex component 6 protein 20130301 {GO:0000145=IEA, GO:0005886=TAS, GO:0030218=IEA, GO:0015031=IEA, GO:0044267=TAS, GO:0016044=TAS, GO:0006904=IEA} cellular membrane organization, cellular protein metabolic process, erythrocyte differentiation, protein transport, vesicle docking involved in exocytosis exocyst, plasma membrane Human EXOC6B UniProtKB UniProtKB {GO:0000145=GO_REF:0000002, GO:0015031=GO_REF:0000037, GO:0006904=GO_REF:0000002} Q9Y2D4 Exocyst complex component 6B protein 20130413 {GO:0000145=IEA, GO:0015031=IEA, GO:0006904=IEA} protein transport, vesicle docking involved in exocytosis exocyst Human UniProtKB-KW:KW-0653 EXOC7 BHF-UCL UniProtKB {GO:0005515=PMID:16148947, GO:0000145=GO_REF:0000002, GO:0005815=PMID:18000879, GO:0005886=Reactome:REACT_15394, GO:0034451=PMID:18000879, GO:0032584=GO_REF:0000019, GO:0015031=GO_REF:0000037, GO:0006887=GO_REF:0000037, GO:0044267=Reactome:REACT_17015, GO:0016044=Reactome:REACT_11123, GO:0005829=GO_REF:0000039} Q9UPT5 Exocyst complex component 7 protein 20080604 {GO:0005515=IPI, GO:0000145=IEA, GO:0005815=IDA, GO:0005886=TAS, GO:0034451=IDA, GO:0032584=IEA, GO:0015031=IEA, GO:0006887=IEA, GO:0044267=TAS, GO:0016044=TAS, GO:0005829=IEA} cellular membrane organization, cellular protein metabolic process, exocytosis, protein transport centriolar satellite, cytosol, exocyst, growth cone membrane, microtubule organizing center, plasma membrane protein binding Human EXOC8 HPA UniProtKB {GO:0005515=PMID:21241894, GO:0005737=GO_REF:0000052, GO:0000145=GO_REF:0000019, GO:0005543=GO_REF:0000002, GO:0005886=Reactome:REACT_15394, GO:0005634=GO_REF:0000052, GO:0034613=GO_REF:0000019, GO:0015031=GO_REF:0000037, GO:0006887=GO_REF:0000037, GO:0044267=Reactome:REACT_17015, GO:0016044=Reactome:REACT_11123, GO:0030426=GO_REF:0000039} Q8IYI6 Exocyst complex component 8 protein 20101115 {GO:0005515=IPI, GO:0005737=IDA, GO:0000145=IEA, GO:0005543=IEA, GO:0005886=TAS, GO:0005634=IDA, GO:0034613=IEA, GO:0015031=IEA, GO:0006887=IEA, GO:0044267=TAS, GO:0016044=TAS, GO:0030426=IEA} cellular membrane organization, cellular protein localization, cellular protein metabolic process, exocytosis, protein transport cytoplasm, exocyst, growth cone, nucleus, plasma membrane phospholipid binding, protein binding Human EXOG UniProtKB UniProtKB {GO:0008150=GO_REF:0000015, GO:0004519=PMID:10231028, GO:0016787=GO_REF:0000002, GO:0005743=GO_REF:0000039, GO:0005575=GO_REF:0000015, GO:0003676=GO_REF:0000002, GO:0046872=GO_REF:0000037} Q9Y2C4 Nuclease EXOG, mitochondrial protein 20061026 {GO:0008150=ND, GO:0004519=NAS, GO:0016787=IEA, GO:0005743=IEA, GO:0005575=ND, GO:0003676=IEA, GO:0046872=IEA} biological_process cellular_component, mitochondrial inner membrane endonuclease activity, hydrolase activity, metal ion binding, nucleic acid binding Human EXOSC1 HPA UniProtKB {GO:0005515=PMID:15231747, GO:0010467=Reactome:REACT_71, GO:0016070=Reactome:REACT_21257, GO:0016071=Reactome:REACT_20605, GO:0003723=PMID:11812149, GO:0006364=GO_REF:0000037, GO:0005730=PMID:11812149, GO:0004532=PMID:17174896, GO:0043928=Reactome:REACT_20619, GO:0005634=GO_REF:0000052, GO:0000178=PMID:20531389, GO:0005829=Reactome:REACT_25297, GO:0000288=Reactome:REACT_20639} Q9Y3B2 Exosome complex component CSL4 protein 20110516 {GO:0005515=IPI, GO:0010467=TAS, GO:0016070=TAS, GO:0016071=TAS, GO:0003723=NAS, GO:0006364=IEA, GO:0005730=IDA, GO:0004532=IDA, GO:0043928=TAS, GO:0005634=IDA, GO:0000178=IDA, GO:0005829=TAS, GO:0000288=TAS} RNA metabolic process, exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay, gene expression, mRNA metabolic process, nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay, rRNA processing cytosol, exosome (RNase complex), nucleolus, nucleus RNA binding, exoribonuclease activity, protein binding Human EXOSC10 HPA UniProtKB {GO:0005515=PMID:17412707, GO:0006396=GO_REF:0000002, GO:0008408=GO_REF:0000002, GO:0000460=PMID:17412707, GO:0071028=PMID:17545563, GO:0003723=GO_REF:0000037, GO:0000956=PMID:17545563, GO:0005730=GO_REF:0000052, GO:0071035=PMID:16455498, GO:0004532=PMID:17174896, GO:0035327=PMID:20699273, GO:0005634=GO_REF:0000052, GO:0009048=GO_REF:0000019, GO:0071034=PMID:19056938, GO:0003676=GO_REF:0000002, GO:0000178=PMID:20531389, GO:0005737=GO_REF:0000052, GO:0000184=PMID:22890540, GO:0000166=GO_REF:0000002, GO:0071044=PMID:18172165, GO:0000176=GO_REF:0000002, GO:0071048=PMID:20699273} Q01780 Exosome component 10 protein 20111111 {GO:0005515=IPI, GO:0006396=IEA, GO:0008408=IEA, GO:0000460=IMP, GO:0071028=IMP, GO:0003723=IEA, GO:0000956=IMP, GO:0005730=IDA, GO:0071035=IMP, GO:0004532=IDA, GO:0035327=IMP, GO:0005634=IDA, GO:0009048=IEA, GO:0071034=IMP, GO:0003676=IEA, GO:0000178=IDA, GO:0005737=IDA, GO:0000184=IMP, GO:0000166=IEA, GO:0071044=IMP, GO:0000176=IEA, GO:0071048=IMP} CUT catabolic process, RNA processing, dosage compensation by inactivation of X chromosome, histone mRNA catabolic process, maturation of 5.8S rRNA, nuclear mRNA surveillance, nuclear polyadenylation-dependent rRNA catabolic process, nuclear retention of unspliced pre-mRNA at the site of transcription, nuclear-transcribed mRNA catabolic process, nuclear-transcribed mRNA catabolic process, nonsense-mediated decay cytoplasm, exosome (RNase complex), nuclear exosome (RNase complex), nucleolus, nucleus, transcriptionally active chromatin 3'-5' exonuclease activity, RNA binding, exoribonuclease activity, nucleic acid binding, nucleotide binding, protein binding Human EXOSC2 IntAct UniProtKB {GO:0005515=PMID:20531389, GO:0010467=Reactome:REACT_71, GO:0016070=Reactome:REACT_21257, GO:0016071=Reactome:REACT_20605, GO:0030307=PMID:17545563, GO:0003723=GO_REF:0000002, GO:0006364=GO_REF:0000037, GO:0008312=PMID:8600032, GO:0005730=GO_REF:0000039, GO:0043928=Reactome:REACT_20619, GO:0004532=PMID:17174896, GO:0005634=PMID:17545563, GO:0000178=PMID:20531389, GO:0005829=Reactome:REACT_25297, GO:0004527=GO_REF:0000038, GO:0005737=PMID:17545563, GO:0000175=PMID:8600032, GO:0000288=Reactome:REACT_20639} Q13868 Exosome complex component RRP4 protein 20130415 {GO:0005515=IPI, GO:0010467=TAS, GO:0016070=TAS, GO:0016071=TAS, GO:0030307=IMP, GO:0003723=IEA, GO:0006364=IEA, GO:0008312=TAS, GO:0005730=IEA, GO:0043928=TAS, GO:0004532=IDA, GO:0005634=IDA, GO:0000178=IDA, GO:0005829=TAS, GO:0004527=IEA, GO:0005737=IDA, GO:0000175=TAS, GO:0000288=TAS} RNA metabolic process, exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay, gene expression, mRNA metabolic process, nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay, positive regulation of cell growth, rRNA processing cytoplasm, cytosol, exosome (RNase complex), nucleolus, nucleus 3'-5'-exoribonuclease activity, 7S RNA binding, RNA binding, exonuclease activity, exoribonuclease activity, protein binding Human UniProtKB:Q8TF46-1 EXOSC3 IntAct UniProtKB {GO:0005515=PMID:21255825, GO:0010467=Reactome:REACT_71, GO:0016070=Reactome:REACT_21257, GO:0016071=Reactome:REACT_20605, GO:0003723=GO_REF:0000037, GO:0006364=PMID:11110791, GO:0045190=GO_REF:0000024, GO:0005730=PMID:20531389, GO:0043928=Reactome:REACT_20619, GO:0035327=PMID:20699273, GO:0004532=PMID:17174896, GO:0005634=PMID:17545563, GO:0071034=PMID:19056938, GO:0000178=PMID:20531389, GO:0005829=Reactome:REACT_25297, GO:0045006=PMID:21255825, GO:0005737=PMID:17545563, GO:0000175=PMID:11110791, GO:0000177=PMID:11110791, GO:0000176=PMID:11110791, GO:0000288=Reactome:REACT_20639} Q9NQT5 Exosome complex component RRP40 protein 20130415 {GO:0005515=IPI, GO:0010467=TAS, GO:0016070=TAS, GO:0016071=TAS, GO:0003723=IEA, GO:0006364=IDA, GO:0045190=ISS, GO:0005730=IDA, GO:0043928=TAS, GO:0035327=IMP, GO:0004532=IDA, GO:0005634=IDA, GO:0071034=IMP, GO:0000178=IDA, GO:0005829=TAS, GO:0045006=IDA, GO:0005737=IDA, GO:0000175=NAS, GO:0000177=IDA, GO:0000176=IDA, GO:0000288=TAS} CUT catabolic process, DNA deamination, RNA metabolic process, exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay, gene expression, isotype switching, mRNA metabolic process, nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay, rRNA processing cytoplasm, cytoplasmic exosome (RNase complex), cytosol, exosome (RNase complex), nuclear exosome (RNase complex), nucleolus, nucleus, transcriptionally active chromatin 3'-5'-exoribonuclease activity, RNA binding, exoribonuclease activity, protein binding Human UniProtKB:Q9Y2L1 EXOSC4 IntAct UniProtKB {GO:0005515=PMID:21255825, GO:0010467=Reactome:REACT_71, GO:0000460=PMID:20368444, GO:0016070=Reactome:REACT_21257, GO:0016071=Reactome:REACT_20605, GO:0030307=PMID:17545563, GO:0006364=PMID:11110791, GO:0071028=PMID:17545563, GO:0005730=PMID:11110791, GO:0000956=PMID:17545563, GO:0043928=Reactome:REACT_20619, GO:0035327=PMID:20699273, GO:0004532=PMID:17174896, GO:0005634=PMID:17545563, GO:0000178=PMID:20531389, GO:0005829=Reactome:REACT_25297, GO:0045006=PMID:21255825, GO:0051607=PMID:21791617, GO:0005737=PMID:17545563, GO:0000175=PMID:11110791, GO:0071044=PMID:18172165, GO:0017091=PMID:16912217, GO:0000288=Reactome:REACT_20639} Q9NPD3 Exosome complex component RRP41 protein 20130415 {GO:0005515=IPI, GO:0010467=TAS, GO:0000460=IMP, GO:0016070=TAS, GO:0016071=TAS, GO:0030307=IMP, GO:0006364=NAS, GO:0071028=IMP, GO:0005730=NAS, GO:0000956=IMP, GO:0043928=TAS, GO:0035327=IMP, GO:0004532=IDA, GO:0005634=IDA, GO:0000178=IDA, GO:0005829=TAS, GO:0045006=IDA, GO:0051607=IMP, GO:0005737=IDA, GO:0000175=NAS, GO:0071044=IMP, GO:0017091=IDA, GO:0000288=TAS} DNA deamination, RNA metabolic process, defense response to virus, exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay, gene expression, histone mRNA catabolic process, mRNA metabolic process, maturation of 5.8S rRNA, nuclear mRNA surveillance, nuclear-transcribed mRNA catabolic process, nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay, positive regulation of cell growth, rRNA processing cytoplasm, cytosol, exosome (RNase complex), nucleolus, nucleus, transcriptionally active chromatin 3'-5'-exoribonuclease activity, AU-rich element binding, exoribonuclease activity, protein binding Human UniProtKB:Q9NQT5 EXOSC5 Reactome UniProtKB {GO:0005515=PMID:11812149, GO:0010467=Reactome:REACT_71, GO:0016070=Reactome:REACT_21257, GO:0016071=Reactome:REACT_20605, GO:0003723=GO_REF:0000037, GO:0006364=PMID:11110791, GO:0005730=PMID:11110791, GO:0043928=Reactome:REACT_20619, GO:0035327=PMID:20699273, GO:0004532=PMID:17174896, GO:0000178=PMID:20531389, GO:0005829=Reactome:REACT_25297, GO:0045006=PMID:21255825, GO:0005737=PMID:11110791, GO:0051607=PMID:21791617, GO:0000175=PMID:11110791, GO:0000288=Reactome:REACT_20639} Q9NQT4 Exosome complex component RRP46 protein 20130301 {GO:0005515=IPI, GO:0010467=TAS, GO:0016070=TAS, GO:0016071=TAS, GO:0003723=IEA, GO:0006364=NAS, GO:0005730=NAS, GO:0043928=TAS, GO:0035327=IMP, GO:0004532=IDA, GO:0000178=IDA, GO:0005829=TAS, GO:0045006=IDA, GO:0005737=NAS, GO:0051607=IMP, GO:0000175=NAS, GO:0000288=TAS} DNA deamination, RNA metabolic process, defense response to virus, exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay, gene expression, mRNA metabolic process, nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay, rRNA processing cytoplasm, cytosol, exosome (RNase complex), nucleolus, transcriptionally active chromatin 3'-5'-exoribonuclease activity, RNA binding, exoribonuclease activity, protein binding Human EXOSC6 Reactome UniProtKB {GO:0010467=Reactome:REACT_71, GO:0016070=Reactome:REACT_21257, GO:0016071=Reactome:REACT_20605, GO:0003723=GO_REF:0000037, GO:0006364=GO_REF:0000037, GO:0045190=GO_REF:0000024, GO:0005730=GO_REF:0000039, GO:0004532=PMID:17174896, GO:0043928=Reactome:REACT_20619, GO:0000178=PMID:20531389, GO:0005829=Reactome:REACT_25297, GO:0045006=PMID:21255825, GO:0000288=Reactome:REACT_20639} Q5RKV6 Exosome complex component MTR3 protein 20130301 {GO:0010467=TAS, GO:0016070=TAS, GO:0016071=TAS, GO:0003723=IEA, GO:0006364=IEA, GO:0045190=ISS, GO:0005730=IEA, GO:0004532=IDA, GO:0043928=TAS, GO:0000178=IDA, GO:0005829=TAS, GO:0045006=IDA, GO:0000288=TAS} DNA deamination, RNA metabolic process, exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay, gene expression, isotype switching, mRNA metabolic process, nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay, rRNA processing cytosol, exosome (RNase complex), nucleolus RNA binding, exoribonuclease activity Human EXOSC7 Reactome UniProtKB {GO:0005515=PMID:21876179, GO:0010467=Reactome:REACT_71, GO:0016070=Reactome:REACT_21257, GO:0016071=Reactome:REACT_20605, GO:0006364=PMID:11849973, GO:0003723=PMID:11849973, GO:0005730=GO_REF:0000039, GO:0043928=Reactome:REACT_20619, GO:0004532=PMID:17174896, GO:0000178=PMID:20531389, GO:0006401=PMID:11719186, GO:0005829=Reactome:REACT_25297, GO:0000175=PMID:11849973, GO:0000288=Reactome:REACT_20639} Q15024 Exosome complex component RRP42 protein 20130301 {GO:0005515=IPI, GO:0010467=TAS, GO:0016070=TAS, GO:0016071=TAS, GO:0006364=TAS, GO:0003723=TAS, GO:0005730=IEA, GO:0043928=TAS, GO:0004532=IDA, GO:0000178=IDA, GO:0006401=NAS, GO:0005829=TAS, GO:0000175=TAS, GO:0000288=TAS} RNA catabolic process, RNA metabolic process, exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay, gene expression, mRNA metabolic process, nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay, rRNA processing cytosol, exosome (RNase complex), nucleolus 3'-5'-exoribonuclease activity, RNA binding, exoribonuclease activity, protein binding Human EXOSC8 IntAct UniProtKB {GO:0005515=PMID:21255825, GO:0010467=Reactome:REACT_71, GO:0016070=Reactome:REACT_21257, GO:0016071=Reactome:REACT_20605, GO:0006364=GO_REF:0000037, GO:0005730=GO_REF:0000039, GO:0043928=Reactome:REACT_20619, GO:0004532=PMID:17174896, GO:0005634=PMID:17545563, GO:0000178=PMID:20531389, GO:0005829=Reactome:REACT_25297, GO:0008150=GO_REF:0000015, GO:0005737=PMID:17545563, GO:0017091=PMID:16912217, GO:0000288=Reactome:REACT_20639} Q96B26 Exosome complex component RRP43 protein 20130415 {GO:0005515=IPI, GO:0010467=TAS, GO:0016070=TAS, GO:0016071=TAS, GO:0006364=IEA, GO:0005730=IEA, GO:0043928=TAS, GO:0004532=IDA, GO:0005634=IDA, GO:0000178=IDA, GO:0005829=TAS, GO:0008150=ND, GO:0005737=IDA, GO:0017091=IDA, GO:0000288=TAS} RNA metabolic process, biological_process, exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay, gene expression, mRNA metabolic process, nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay, rRNA processing cytoplasm, cytosol, exosome (RNase complex), nucleolus, nucleus AU-rich element binding, exoribonuclease activity, protein binding Human UniProtKB:Q9NQT5 EXOSC9 Reactome UniProtKB {GO:0010467=Reactome:REACT_71, GO:0016070=Reactome:REACT_21257, GO:0016071=Reactome:REACT_20605, GO:0030307=PMID:17545563, GO:0003723=PMID:11879549, GO:0006364=PMID:11879549, GO:0071028=PMID:17545563, GO:0005730=GO_REF:0000039, GO:0071035=PMID:16455498, GO:0000956=PMID:17545563, GO:0043928=Reactome:REACT_20619, GO:0004532=PMID:17174896, GO:0005634=PMID:17545563, GO:0000178=PMID:20531389, GO:0005829=Reactome:REACT_25297, GO:0005737=PMID:17545563, GO:0006955=PMID:11879549, GO:0000175=PMID:11879549, GO:0000176=PMID:22791713, GO:0017091=PMID:11782436, GO:0000288=Reactome:REACT_20639} Q06265 Exosome complex component RRP45 protein 20130301 {GO:0010467=TAS, GO:0016070=TAS, GO:0016071=TAS, GO:0030307=IMP, GO:0003723=NAS, GO:0006364=NAS, GO:0071028=IMP, GO:0005730=IEA, GO:0071035=IMP, GO:0000956=IMP, GO:0043928=TAS, GO:0004532=IDA, GO:0005634=IDA, GO:0000178=IDA, GO:0005829=TAS, GO:0005737=IDA, GO:0006955=NAS, GO:0000175=NAS, GO:0000176=IDA, GO:0017091=IDA, GO:0000288=TAS} RNA metabolic process, exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay, gene expression, immune response, mRNA metabolic process, nuclear mRNA surveillance, nuclear polyadenylation-dependent rRNA catabolic process, nuclear-transcribed mRNA catabolic process, nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay, positive regulation of cell growth, rRNA processing cytoplasm, cytosol, exosome (RNase complex), nuclear exosome (RNase complex), nucleolus, nucleus 3'-5'-exoribonuclease activity, AU-rich element binding, RNA binding, exoribonuclease activity Human EXPH5 UniProtKB UniProtKB {GO:0045921=PMID:19966785, GO:0017137=PMID:16880209, GO:0071985=PMID:19966785, GO:0050714=PMID:19966785, GO:0006886=GO_REF:0000002, GO:0005768=PMID:19966785} Q8NEV8 Exophilin-5 protein 20110803 {GO:0045921=IMP, GO:0017137=IPI, GO:0071985=IMP, GO:0050714=IMP, GO:0006886=IEA, GO:0005768=IDA} intracellular protein transport, multivesicular body sorting pathway, positive regulation of exocytosis, positive regulation of protein secretion endosome Rab GTPase binding Human UniProtKB:O00194 EXT1 BHF-UCL UniProtKB {GO:0007369=GO_REF:0000019, GO:0005783=PMID:9620772, GO:0030176=GO_REF:0000024, GO:0015012=PMID:10639137, GO:0044281=Reactome:REACT_111217, GO:0015014=PMID:17761672, GO:0042803=PMID:12907669, GO:0021772=GO_REF:0000019, GO:0007411=GO_REF:0000019, GO:0033692=PMID:12907669, GO:0030203=Reactome:REACT_121315, GO:0008375=PMID:12907669, GO:0050508=PMID:12907669, GO:0005794=PMID:10639137, GO:0050509=PMID:12907669, GO:0072498=GO_REF:0000019, GO:0046982=PMID:12907669, GO:0005975=Reactome:REACT_474, GO:0016757=PMID:12907669, GO:0015020=PMID:12907669, GO:0006024=PMID:12907669, GO:0007165=PMID:10878610, GO:0001501=PMID:9620772, GO:0007492=GO_REF:0000019, GO:0016020=GO_REF:0000002, GO:0000139=PMID:12907669, GO:0001503=PMID:7550340, GO:0005789=PMID:9620772, GO:0006486=GO_REF:0000041, GO:0007498=GO_REF:0000019, GO:0016021=PMID:9620772, GO:0042328=PMID:12907669} Q16394 Exostosin-1 protein 20080228 {GO:0007369=IEA, GO:0005783=IDA, GO:0030176=ISS, GO:0015012=IDA, GO:0044281=TAS, GO:0015014=IMP, GO:0042803=IDA, GO:0021772=IEA, GO:0007411=IEA, GO:0033692=IDA, GO:0030203=TAS, GO:0008375=IDA, GO:0050508=NAS, GO:0005794=IDA, GO:0050509=NAS, GO:0072498=IEA, GO:0046982=IPI, GO:0005975=TAS, GO:0016757=IDA, GO:0015020=IDA, GO:0006024=IDA, GO:0007165=TAS, GO:0001501=TAS, GO:0007492=IEA, GO:0016020=IEA, GO:0000139=TAS, GO:0001503=IMP, GO:0005789=NAS, GO:0006486=IEA, GO:0007498=IEA, GO:0016021=TAS, GO:0042328=NAS} axon guidance, carbohydrate metabolic process, cellular polysaccharide biosynthetic process, embryonic skeletal joint development, endoderm development, gastrulation, glycosaminoglycan biosynthetic process, glycosaminoglycan metabolic process, heparan sulfate proteoglycan biosynthetic process, heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process, mesoderm development, olfactory bulb development, ossification, protein glycosylation, signal transduction, skeletal system development, small molecule metabolic process Golgi apparatus, Golgi membrane, endoplasmic reticulum, endoplasmic reticulum membrane, integral to endoplasmic reticulum membrane, integral to membrane, membrane N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity, acetylglucosaminyltransferase activity, glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity, glucuronosyltransferase activity, heparan sulfate N-acetylglucosaminyltransferase activity, protein heterodimerization activity, protein homodimerization activity, transferase activity, transferring glycosyl groups Human EXT2 BHF-UCL UniProtKB {GO:0005783=GO_REF:0000024, GO:0031227=GO_REF:0000002, GO:0015012=PMID:17761672, GO:0044281=Reactome:REACT_111217, GO:0015014=PMID:17761672, GO:0042803=PMID:12907669, GO:0030154=GO_REF:0000019, GO:0033692=PMID:12907669, GO:0030203=Reactome:REACT_121315, GO:0008375=PMID:12907669, GO:0050508=GO_REF:0000003, GO:0050509=PMID:12907669, GO:0005794=GO_REF:0000024, GO:0001707=GO_REF:0000019, GO:0046982=PMID:12907669, GO:0005975=Reactome:REACT_474, GO:0016757=PMID:12907669, GO:0015020=PMID:12907669, GO:0006024=PMID:12907669, GO:0007165=PMID:10878610, GO:0000139=Reactome:REACT_121320, GO:0001503=PMID:9326317, GO:0005789=PMID:10639137, GO:0006486=GO_REF:0000041, GO:0016021=GO_REF:0000037, GO:0042328=PMID:12907669} Q93063 Exostosin-2 protein 20080228 {GO:0005783=ISS, GO:0031227=IEA, GO:0015012=IMP, GO:0044281=TAS, GO:0015014=IMP, GO:0042803=IDA, GO:0030154=IEA, GO:0033692=IDA, GO:0030203=TAS, GO:0008375=IDA, GO:0050508=IEA, GO:0050509=NAS, GO:0005794=ISS, GO:0001707=IEA, GO:0046982=IPI, GO:0005975=TAS, GO:0016757=IDA, GO:0015020=IDA, GO:0006024=IDA, GO:0007165=TAS, GO:0000139=TAS, GO:0001503=IMP, GO:0005789=TAS, GO:0006486=IEA, GO:0016021=IEA, GO:0042328=NAS} carbohydrate metabolic process, cell differentiation, cellular polysaccharide biosynthetic process, glycosaminoglycan biosynthetic process, glycosaminoglycan metabolic process, heparan sulfate proteoglycan biosynthetic process, heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process, mesoderm formation, ossification, protein glycosylation, signal transduction, small molecule metabolic process Golgi apparatus, Golgi membrane, endoplasmic reticulum, endoplasmic reticulum membrane, integral to membrane, intrinsic to endoplasmic reticulum membrane N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity, acetylglucosaminyltransferase activity, glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity, glucuronosyltransferase activity, heparan sulfate N-acetylglucosaminyltransferase activity, protein heterodimerization activity, protein homodimerization activity, transferase activity, transferring glycosyl groups Human EXTL1 PINC UniProtKB {GO:0001501=PMID:9037597, GO:0050508=GO_REF:0000003, GO:0031227=GO_REF:0000002, GO:0006486=GO_REF:0000041, GO:0016021=GO_REF:0000037} Q92935 Exostosin-like 1 protein 20030904 {GO:0001501=TAS, GO:0050508=IEA, GO:0031227=IEA, GO:0006486=IEA, GO:0016021=IEA} protein glycosylation, skeletal system development integral to membrane, intrinsic to endoplasmic reticulum membrane glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity Human EXTL3 BHF-UCL UniProtKB {GO:0016758=GO_REF:0000002, GO:0030307=GO_REF:0000019, GO:0005783=PMID:10639137, GO:0031227=GO_REF:0000002, GO:0015012=GO_REF:0000041, GO:0046872=GO_REF:0000037, GO:0030968=Reactome:REACT_18356, GO:0001888=GO_REF:0000003, GO:0016020=GO_REF:0000002, GO:0005789=Reactome:REACT_115825, GO:0016021=GO_REF:0000037, GO:0006987=Reactome:REACT_18368, GO:0044267=Reactome:REACT_17015} O43909 Exostosin-like 3 protein 20080228 {GO:0016758=IEA, GO:0030307=IEA, GO:0005783=IDA, GO:0031227=IEA, GO:0015012=IEA, GO:0046872=IEA, GO:0030968=TAS, GO:0001888=IEA, GO:0016020=IEA, GO:0005789=TAS, GO:0016021=IEA, GO:0006987=TAS, GO:0044267=TAS} activation of signaling protein activity involved in unfolded protein response, cellular protein metabolic process, endoplasmic reticulum unfolded protein response, heparan sulfate proteoglycan biosynthetic process, positive regulation of cell growth endoplasmic reticulum, endoplasmic reticulum membrane, integral to membrane, intrinsic to endoplasmic reticulum membrane, membrane glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity, metal ion binding, transferase activity, transferring hexosyl groups Human EYA1 PINC UniProtKB {GO:0005515=PMID:15141091, GO:0001656=GO_REF:0000019, GO:0007389=GO_REF:0000019, GO:0001658=GO_REF:0000019, GO:0007605=PMID:9020840, GO:0000132=GO_REF:0000019, GO:0035088=GO_REF:0000019, GO:0005634=PMID:19497856, GO:0048704=GO_REF:0000019, GO:0045739=PMID:19234442, GO:0048752=GO_REF:0000019, GO:0009653=PMID:9020840, GO:0046872=GO_REF:0000037, GO:0006302=PMID:19234442, GO:0005737=PMID:19497856, GO:0010212=PMID:19234442, GO:0045944=GO_REF:0000019, GO:0090103=GO_REF:0000019, GO:0072513=GO_REF:0000019, GO:0014706=GO_REF:0000019, GO:0042474=GO_REF:0000019, GO:0042473=GO_REF:0000019, GO:0004725=PMID:19234442, GO:0045747=GO_REF:0000019, GO:0050679=GO_REF:0000019, GO:0043066=GO_REF:0000019, GO:0016576=PMID:19234442, GO:0016925=GO_REF:0000024, GO:0035909=GO_REF:0000019, GO:0007275=GO_REF:0000002, GO:0003151=GO_REF:0000019, GO:0071600=GO_REF:0000019, GO:0006351=GO_REF:0000037, GO:0060037=GO_REF:0000019, GO:0045165=GO_REF:0000019, GO:0045664=GO_REF:0000019, GO:0060487=GO_REF:0000019, GO:0034613=GO_REF:0000019} Q99502 Eyes absent homolog 1 protein 20030904 {GO:0005515=IPI, GO:0001656=IEA, GO:0007389=IEA, GO:0001658=IEA, GO:0007605=TAS, GO:0000132=IEA, GO:0035088=IEA, GO:0005634=IDA, GO:0048704=IEA, GO:0045739=IMP, GO:0048752=IEA, GO:0009653=TAS, GO:0046872=IEA, GO:0006302=IMP, GO:0005737=IDA, GO:0010212=IDA, GO:0045944=IEA, GO:0090103=IEA, GO:0072513=IEA, GO:0014706=IEA, GO:0042474=IEA, GO:0042473=IEA, GO:0004725=IDA, GO:0045747=IEA, GO:0050679=IEA, GO:0043066=IEA, GO:0016576=IDA, GO:0016925=ISS, GO:0035909=IEA, GO:0007275=IEA, GO:0003151=IEA, GO:0071600=IEA, GO:0006351=IEA, GO:0060037=IEA, GO:0045165=IEA, GO:0045664=IEA, GO:0060487=IEA, GO:0034613=IEA} anatomical structure morphogenesis, aorta morphogenesis, branching involved in ureteric bud morphogenesis, cell fate commitment, cellular protein localization, cochlea morphogenesis, double-strand break repair, embryonic skeletal system morphogenesis, establishment of mitotic spindle orientation, establishment or maintenance of apical/basal cell polarity, histone dephosphorylation, lung epithelial cell differentiation, metanephros development, middle ear morphogenesis, multicellular organismal development, negative regulation of apoptotic process, otic vesicle morphogenesis, outer ear morphogenesis, outflow tract morphogenesis, pattern specification process, pharyngeal system development, positive regulation of DNA repair, positive regulation of Notch signaling pathway, positive regulation of epithelial cell proliferation, positive regulation of secondary heart field cardioblast proliferation, positive regulation of transcription from RNA polymerase II promoter, protein sumoylation, regulation of neuron differentiation, response to ionizing radiation, semicircular canal morphogenesis, sensory perception of sound, striated muscle tissue development, transcription, DNA-dependent cytoplasm, nucleus metal ion binding, protein binding, protein tyrosine phosphatase activity Human EYA2 GOC UniProtKB {GO:0005515=PMID:19497856, GO:0006355=GO_REF:0000037, GO:0000287=PMID:19351884, GO:0016576=PMID:19351884, GO:0006915=GO_REF:0000019, GO:0007275=GO_REF:0000002, GO:0005634=GO_REF:0000039, GO:0035335=PMID:19351884, GO:0006351=GO_REF:0000037, GO:0005739=GO_REF:0000052, GO:0007501=PMID:9020840, GO:0006281=GO_REF:0000037, GO:0014706=GO_REF:0000019, GO:0004725=PMID:19351884} O00167 Eyes absent homolog 2 protein 20130413 {GO:0005515=IPI, GO:0006355=IEA, GO:0000287=IDA, GO:0016576=IDA, GO:0006915=IEA, GO:0007275=IEA, GO:0005634=IEA, GO:0035335=IDA, GO:0006351=IEA, GO:0005739=IDA, GO:0007501=TAS, GO:0006281=IEA, GO:0014706=IEA, GO:0004725=IDA} DNA repair, apoptotic process, histone dephosphorylation, mesodermal cell fate specification, multicellular organismal development, peptidyl-tyrosine dephosphorylation, regulation of transcription, DNA-dependent, striated muscle tissue development, transcription, DNA-dependent mitochondrion, nucleus magnesium ion binding, protein binding, protein tyrosine phosphatase activity Human EYA3 GOC UniProtKB {GO:0005515=PMID:19234442, GO:0005667=GO_REF:0000019, GO:0006355=GO_REF:0000037, GO:0016576=PMID:19234442, GO:0005634=PMID:19234442, GO:0007275=GO_REF:0000037, GO:0045739=PMID:19234442, GO:0009653=PMID:9020840, GO:0035335=PMID:19351884, GO:0006351=GO_REF:0000037, GO:0046872=GO_REF:0000037, GO:0006302=PMID:19234442, GO:0005737=GO_REF:0000039, GO:0003682=GO_REF:0000019, GO:0010212=PMID:19234442, GO:0008138=GO_REF:0000019, GO:0007601=PMID:9049631, GO:0004725=PMID:19234442} Q99504 Eyes absent homolog 3 protein 20130413 {GO:0005515=IPI, GO:0005667=IEA, GO:0006355=IEA, GO:0016576=IDA, GO:0005634=IDA, GO:0007275=IEA, GO:0045739=IMP, GO:0009653=TAS, GO:0035335=IDA, GO:0006351=IEA, GO:0046872=IEA, GO:0006302=IMP, GO:0005737=IEA, GO:0003682=IEA, GO:0010212=IDA, GO:0008138=IEA, GO:0007601=TAS, GO:0004725=IDA} anatomical structure morphogenesis, double-strand break repair, histone dephosphorylation, multicellular organismal development, peptidyl-tyrosine dephosphorylation, positive regulation of DNA repair, regulation of transcription, DNA-dependent, response to ionizing radiation, transcription, DNA-dependent, visual perception cytoplasm, nucleus, transcription factor complex chromatin binding, metal ion binding, protein binding, protein tyrosine phosphatase activity, protein tyrosine/serine/threonine phosphatase activity Human EYA4 PINC UniProtKB {GO:0006355=GO_REF:0000037, GO:0007605=GO_REF:0000019, GO:0007275=GO_REF:0000002, GO:0005634=GO_REF:0000039, GO:0009653=PMID:9887327, GO:0046872=GO_REF:0000037, GO:0006351=GO_REF:0000037, GO:0005737=GO_REF:0000039, GO:0006281=GO_REF:0000037, GO:0042474=GO_REF:0000019, GO:0007601=PMID:9887327, GO:0004725=GO_REF:0000003, GO:0016568=GO_REF:0000037} O95677 Eyes absent homolog 4 protein 20030904 {GO:0006355=IEA, GO:0007605=IEA, GO:0007275=IEA, GO:0005634=IEA, GO:0009653=TAS, GO:0046872=IEA, GO:0006351=IEA, GO:0005737=IEA, GO:0006281=IEA, GO:0042474=IEA, GO:0007601=TAS, GO:0004725=IEA, GO:0016568=IEA} DNA repair, anatomical structure morphogenesis, chromatin modification, middle ear morphogenesis, multicellular organismal development, regulation of transcription, DNA-dependent, sensory perception of sound, transcription, DNA-dependent, visual perception cytoplasm, nucleus metal ion binding, protein tyrosine phosphatase activity Human EZH1 HPA UniProtKB {GO:0035098=PMID:20075857, GO:0003682=GO_REF:0000002, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0000122=GO_REF:0000019, GO:0009653=PMID:8921387, GO:0046976=GO_REF:0000019, GO:0006351=GO_REF:0000037, GO:0018024=GO_REF:0000002} Q92800 Histone-lysine N-methyltransferase EZH1 protein 20090616 {GO:0035098=IDA, GO:0003682=IEA, GO:0005730=IDA, GO:0005634=IDA, GO:0000122=IEA, GO:0009653=TAS, GO:0046976=IEA, GO:0006351=IEA, GO:0018024=IEA} anatomical structure morphogenesis, negative regulation of transcription from RNA polymerase II promoter, transcription, DNA-dependent ESC/E(Z) complex, nucleolus, nucleus chromatin binding, histone methyltransferase activity (H3-K27 specific), histone-lysine N-methyltransferase activity NOT Human EZH2 IntAct UniProtKB {GO:0005515=PMID:22897849, GO:0071902=PMID:20154697, GO:0021695=GO_REF:0000019, GO:0006325=PMID:8921387, GO:0010718=PMID:20154697, GO:0042054=PMID:15385962, GO:0000084=GO_REF:0000019, GO:0043406=PMID:20154697, GO:0042127=GO_REF:0000019, GO:0014013=GO_REF:0000019, GO:0051154=GO_REF:0000019, GO:0034244=GO_REF:0000019, GO:0070734=GO_REF:0000019, GO:0006355=PMID:8921387, GO:0001047=GO_REF:0000019, GO:0000122=PMID:20154697, GO:0003677=PMID:8954776, GO:0006351=GO_REF:0000037, GO:0070314=GO_REF:0000019, GO:0018024=GO_REF:0000003, GO:0043565=GO_REF:0000019, GO:0045605=GO_REF:0000019, GO:0035098=PMID:15385962, GO:0032320=PMID:20154697, GO:0048387=PMID:16179254, GO:0003682=PMID:20154697, GO:0045814=PMID:20154697, GO:0045120=GO_REF:0000019, GO:0045892=PMID:16179254} Q15910 Histone-lysine N-methyltransferase EZH2 protein 20130415 {GO:0005515=IPI, GO:0071902=IDA, GO:0021695=IEA, GO:0006325=TAS, GO:0010718=IDA, GO:0042054=IDA, GO:0000084=IEA, GO:0043406=IDA, GO:0042127=IEA, GO:0014013=IEA, GO:0051154=IEA, GO:0034244=IEA, GO:0070734=IEA, GO:0006355=TAS, GO:0001047=IEA, GO:0000122=IDA, GO:0003677=TAS, GO:0006351=IEA, GO:0070314=IEA, GO:0018024=IEA, GO:0043565=IEA, GO:0045605=IEA, GO:0035098=IDA, GO:0032320=IDA, GO:0048387=IMP, GO:0003682=IDA, GO:0045814=IDA, GO:0045120=IEA, GO:0045892=IMP} G1 to G0 transition, S phase of mitotic cell cycle, cerebellar cortex development, chromatin organization, histone H3-K27 methylation, negative regulation of epidermal cell differentiation, negative regulation of gene expression, epigenetic, negative regulation of retinoic acid receptor signaling pathway, negative regulation of striated muscle cell differentiation, negative regulation of transcription elongation from RNA polymerase II promoter, negative regulation of transcription from RNA polymerase II promoter, negative regulation of transcription, DNA-dependent, positive regulation of MAP kinase activity, positive regulation of Ras GTPase activity, positive regulation of epithelial to mesenchymal transition, positive regulation of protein serine/threonine kinase activity, regulation of cell proliferation, regulation of gliogenesis, regulation of transcription, DNA-dependent, transcription, DNA-dependent ESC/E(Z) complex, pronucleus DNA binding, chromatin binding, core promoter binding, histone methyltransferase activity, histone-lysine N-methyltransferase activity, protein binding, sequence-specific DNA binding Human UniProtKB:Q8IXJ9 EZR HPA UniProtKB {GO:0008092=GO_REF:0000002, GO:0005515=PMID:21282464, GO:0005886=GO_REF:0000052, GO:0008360=GO_REF:0000037, GO:0005884=PMID:11598191, GO:0031528=GO_REF:0000039, GO:0035088=GO_REF:0000019, GO:0030175=PMID:12082081, GO:0015629=PMID:10793131, GO:0005829=Reactome:REACT_22317, GO:0016323=GO_REF:0000024, GO:0016324=GO_REF:0000039, GO:0005737=GO_REF:0000002, GO:0051015=PMID:10793131, GO:0007411=Reactome:REACT_18266, GO:0030855=GO_REF:0000019, GO:0007159=PMID:12082081, GO:0022614=PMID:12082081, GO:0005932=GO_REF:0000019, GO:0005856=GO_REF:0000002, GO:0050839=PMID:12082081, GO:0007016=PMID:10793131, GO:0051017=PMID:10793131, GO:0005730=GO_REF:0000052, GO:0045177=PMID:12082081, GO:0032587=GO_REF:0000039, GO:0001726=PMID:9852149, GO:0005902=PMID:12082081, GO:0030863=PMID:11598191, GO:0001931=GO_REF:0000019, GO:0005925=PMID:21282464, GO:0019898=PMID:7844168} P15311 Ezrin protein 20100326 {GO:0008092=IEA, GO:0005515=IPI, GO:0005886=IDA, GO:0008360=IEA, GO:0005884=IDA, GO:0031528=IEA, GO:0035088=IEA, GO:0030175=IDA, GO:0015629=IDA, GO:0005829=TAS, GO:0016323=ISS, GO:0016324=IEA, GO:0005737=IEA, GO:0051015=IDA, GO:0007411=TAS, GO:0030855=IEA, GO:0007159=IEP, GO:0022614=IEP, GO:0005932=IEA, GO:0005856=IEA, GO:0050839=IPI, GO:0007016=NAS, GO:0051017=IDA, GO:0005730=IDA, GO:0045177=IDA, GO:0032587=IEA, GO:0001726=IDA, GO:0005902=IDA, GO:0030863=TAS, GO:0001931=IEA, GO:0005925=IDA, GO:0019898=IDA} actin filament bundle assembly, axon guidance, cytoskeletal anchoring at plasma membrane, epithelial cell differentiation, establishment or maintenance of apical/basal cell polarity, leukocyte cell-cell adhesion, membrane to membrane docking, regulation of cell shape actin cytoskeleton, actin filament, apical part of cell, apical plasma membrane, basolateral plasma membrane, cortical cytoskeleton, cytoplasm, cytoskeleton, cytosol, extrinsic to membrane, filopodium, focal adhesion, microtubule basal body, microvillus, microvillus membrane, nucleolus, plasma membrane, ruffle, ruffle membrane, uropod actin filament binding, cell adhesion molecule binding, cytoskeletal protein binding, protein binding Human F10 UniProtKB UniProtKB {GO:0005515=PMID:6323392, GO:0051897=PMID:18612547, GO:0030335=PMID:18612547, GO:0004252=GO_REF:0000002, GO:0005886=Reactome:REACT_1446, GO:0005796=Reactome:REACT_1644, GO:0005509=GO_REF:0000002, GO:0005576=GO_REF:0000002, GO:0031233=PMID:17469850, GO:0017187=Reactome:REACT_1132, GO:0005543=PMID:17469850, GO:0007596=PMID:17469850, GO:0007597=Reactome:REACT_326, GO:0007598=Reactome:REACT_1573, GO:0006508=GO_REF:0000038, GO:0005788=Reactome:REACT_1565, GO:0044267=Reactome:REACT_17015, GO:0043687=Reactome:REACT_22161} Q5JVE8 Factor X light chain protein 20130413 {GO:0005515=IPI, GO:0051897=IDA, GO:0030335=TAS, GO:0004252=IEA, GO:0005886=TAS, GO:0005796=TAS, GO:0005509=IEA, GO:0005576=IEA, GO:0031233=IC, GO:0017187=TAS, GO:0005543=IDA, GO:0007596=IC, GO:0007597=TAS, GO:0007598=TAS, GO:0006508=IEA, GO:0005788=TAS, GO:0044267=TAS, GO:0043687=TAS} blood coagulation, blood coagulation, extrinsic pathway, blood coagulation, intrinsic pathway, cellular protein metabolic process, peptidyl-glutamic acid carboxylation, positive regulation of cell migration, positive regulation of protein kinase B signaling cascade, post-translational protein modification, proteolysis Golgi lumen, endoplasmic reticulum lumen, extracellular region, intrinsic to external side of plasma membrane, plasma membrane calcium ion binding, phospholipid binding, protein binding, serine-type endopeptidase activity Human UniProtKB-KW:KW-0645 F11 BHF-UCL UniProtKB {GO:0005515=PMID:15545266, GO:0004252=PMID:9593722, GO:0005886=Reactome:REACT_2073, GO:0051919=PMID:89876, GO:0005576=Reactome:REACT_177, GO:0005615=PMID:89876, GO:0030193=GO_REF:0000019, GO:0016020=PMID:9593722, GO:0007596=Reactome:REACT_2051, GO:0007597=Reactome:REACT_326, GO:0006508=GO_REF:0000037, GO:0031639=PMID:89876, GO:0070009=GO_REF:0000019, GO:0008201=GO_REF:0000037, GO:0044421=GO_REF:0000019} P03951 Coagulation factor XI protein 20081015 {GO:0005515=IPI, GO:0004252=NAS, GO:0005886=TAS, GO:0051919=IDA, GO:0005576=TAS, GO:0005615=IDA, GO:0030193=IEA, GO:0016020=NAS, GO:0007596=TAS, GO:0007597=TAS, GO:0006508=IEA, GO:0031639=IDA, GO:0070009=IEA, GO:0008201=IEA, GO:0044421=IEA} blood coagulation, blood coagulation, intrinsic pathway, plasminogen activation, positive regulation of fibrinolysis, proteolysis, regulation of blood coagulation extracellular region, extracellular region part, extracellular space, membrane, plasma membrane heparin binding, protein binding, serine-type aminopeptidase activity, serine-type endopeptidase activity Human F11R Reactome UniProtKB {GO:0030054=Reactome:REACT_121319, GO:0005886=Reactome:REACT_19353, GO:0034329=Reactome:REACT_20676, GO:0050900=Reactome:REACT_12051, GO:0045216=Reactome:REACT_19331, GO:0006954=PMID:10395639, GO:0070830=Reactome:REACT_19373, GO:0005911=PMID:10395639, GO:0007596=Reactome:REACT_604, GO:0019048=GO_REF:0000037, GO:0030855=GO_REF:0000019, GO:0007179=Reactome:REACT_120726, GO:0016021=GO_REF:0000037, GO:0005923=GO_REF:0000039, GO:0007155=GO_REF:0000019} Q9Y624 Junctional adhesion molecule A protein 20090827 {GO:0030054=TAS, GO:0005886=TAS, GO:0034329=TAS, GO:0050900=TAS, GO:0045216=TAS, GO:0006954=TAS, GO:0070830=TAS, GO:0005911=TAS, GO:0007596=TAS, GO:0019048=IEA, GO:0030855=IEA, GO:0007179=TAS, GO:0016021=IEA, GO:0005923=IEA, GO:0007155=IEA} blood coagulation, cell adhesion, cell junction assembly, cell-cell junction organization, epithelial cell differentiation, inflammatory response, leukocyte migration, tight junction assembly, transforming growth factor beta receptor signaling pathway, virus-host interaction cell junction, cell-cell junction, integral to membrane, plasma membrane, tight junction Human F12 BHF-UCL UniProtKB {GO:0005515=PMID:8710908, GO:0016540=PMID:18725990, GO:0005886=Reactome:REACT_1455, GO:0004252=PMID:18725990, GO:0051919=PMID:89876, GO:0005576=Reactome:REACT_1455, GO:0005615=PMID:6793628, GO:0051787=PMID:18725990, GO:0051788=PMID:18725990, GO:0016485=PMID:18725990, GO:0010756=PMID:89876, GO:0007596=Reactome:REACT_2051, GO:0030194=PMID:6793628, GO:0045087=PMID:2510163, GO:0002542=PMID:18725990, GO:0007597=PMID:18725990, GO:0006508=GO_REF:0000037, GO:0002353=PMID:18725990, GO:0042730=GO_REF:0000037, GO:0070009=GO_REF:0000019, GO:0031638=PMID:89876} P00748 Coagulation factor XII protein 20081015 {GO:0005515=IPI, GO:0016540=IDA, GO:0005886=TAS, GO:0004252=IDA, GO:0051919=IDA, GO:0005576=TAS, GO:0005615=IDA, GO:0051787=IC, GO:0051788=IDA, GO:0016485=IDA, GO:0010756=IDA, GO:0007596=TAS, GO:0030194=IDA, GO:0045087=TAS, GO:0002542=IDA, GO:0007597=IC, GO:0006508=IEA, GO:0002353=IDA, GO:0042730=IEA, GO:0070009=IEA, GO:0031638=IDA} Factor XII activation, blood coagulation, blood coagulation, intrinsic pathway, fibrinolysis, innate immune response, plasma kallikrein-kinin cascade, positive regulation of blood coagulation, positive regulation of fibrinolysis, positive regulation of plasminogen activation, protein autoprocessing, protein processing, proteolysis, response to misfolded protein, zymogen activation extracellular region, extracellular space, plasma membrane misfolded protein binding, protein binding, serine-type aminopeptidase activity, serine-type endopeptidase activity Human F13A1 ENSEMBL UniProtKB {GO:0018149=GO_REF:0000019, GO:0007596=GO_REF:0000019, GO:0003810=GO_REF:0000019, GO:0002576=Reactome:REACT_318, GO:0030168=Reactome:REACT_798, GO:0031093=Reactome:REACT_21351, GO:0005576=Reactome:REACT_21351, GO:0046872=GO_REF:0000037} Q9NQP5 Coagulation factor XIII A chain protein 20130413 {GO:0018149=IEA, GO:0007596=IEA, GO:0003810=IEA, GO:0002576=TAS, GO:0030168=TAS, GO:0031093=TAS, GO:0005576=TAS, GO:0046872=IEA} blood coagulation, peptide cross-linking, platelet activation, platelet degranulation extracellular region, platelet alpha granule lumen metal ion binding, protein-glutamine gamma-glutamyltransferase activity Human Ensembl:ENSMUSP00000048667 F13B Reactome UniProtKB {GO:0007596=Reactome:REACT_2051, GO:0005576=Reactome:REACT_1314} P05160 Coagulation factor XIII B chain protein 20040824 {GO:0007596=TAS, GO:0005576=TAS} blood coagulation extracellular region Human F2 BHF-UCL UniProtKB {GO:0010544=PMID:17379830, GO:0005515=PMID:8626514, GO:0008284=GO_REF:0000019, GO:0004252=PMID:1672265, GO:0005886=Reactome:REACT_1834, GO:0030307=GO_REF:0000019, GO:0008360=GO_REF:0000019, GO:1900738=PMID:20164183, GO:0050900=Reactome:REACT_12051, GO:0005615=PMID:9639571, GO:0006508=Reactome:REACT_733, GO:0051281=PMID:1672265, GO:0005796=Reactome:REACT_1065, GO:0051480=PMID:19052258, GO:0005509=GO_REF:0000002, GO:0009611=PMID:9639571, GO:0005102=PMID:8626514, GO:0051918=PMID:17379830, GO:0030168=PMID:9038223, GO:0014068=GO_REF:0000019, GO:0005576=Reactome:REACT_23955, GO:0007275=PMID:9639571, GO:0006953=GO_REF:0000037, GO:0045861=PMID:1695900, GO:0048712=PMID:1691280, GO:0017187=Reactome:REACT_1132, GO:0032967=PMID:9639571, GO:0030193=PMID:12855810, GO:0030194=PMID:9038223, GO:0007596=Reactome:REACT_2051, GO:0007597=Reactome:REACT_326, GO:0001934=PMID:7559487, GO:0005788=Reactome:REACT_903, GO:0008083=PMID:8626514, GO:2000379=PMID:17275676, GO:0044267=Reactome:REACT_17015, GO:0042730=PMID:12855810, GO:0007166=PMID:1672265, GO:0070053=PMID:2435757, GO:0043687=Reactome:REACT_22161} P00734 Prothrombin protein 20100329 {GO:0010544=TAS, GO:0005515=IPI, GO:0008284=IEA, GO:0004252=IDA, GO:0005886=TAS, GO:0030307=IEA, GO:0008360=IEA, GO:1900738=IDA, GO:0050900=TAS, GO:0005615=IDA, GO:0006508=TAS, GO:0051281=IDA, GO:0005796=TAS, GO:0051480=IDA, GO:0005509=IEA, GO:0009611=IDA, GO:0005102=IPI, GO:0051918=TAS, GO:0030168=IDA, GO:0014068=IEA, GO:0005576=TAS, GO:0007275=TAS, GO:0006953=IEA, GO:0045861=IDA, GO:0048712=IDA, GO:0017187=TAS, GO:0032967=IDA, GO:0030193=TAS, GO:0030194=IDA, GO:0007596=TAS, GO:0007597=TAS, GO:0001934=IDA, GO:0005788=TAS, GO:0008083=TAS, GO:2000379=IDA, GO:0044267=TAS, GO:0042730=IDA, GO:0007166=IDA, GO:0070053=IDA, GO:0043687=TAS} acute-phase response, blood coagulation, blood coagulation, intrinsic pathway, cell surface receptor signaling pathway, cellular protein metabolic process, cytosolic calcium ion homeostasis, fibrinolysis, leukocyte migration, multicellular organismal development, negative regulation of astrocyte differentiation, negative regulation of fibrinolysis, negative regulation of platelet activation, negative regulation of proteolysis, peptidyl-glutamic acid carboxylation, platelet activation, positive regulation of blood coagulation, positive regulation of cell growth, positive regulation of cell proliferation, positive regulation of collagen biosynthetic process, positive regulation of phosphatidylinositol 3-kinase cascade, positive regulation of phospholipase C-activating G-protein coupled receptor signaling pathway, positive regulation of protein phosphorylation, positive regulation of reactive oxygen species metabolic process, positive regulation of release of sequestered calcium ion into cytosol, post-translational protein modification, proteolysis, regulation of blood coagulation, regulation of cell shape, response to wounding Golgi lumen, endoplasmic reticulum lumen, extracellular region, extracellular space, plasma membrane calcium ion binding, growth factor activity, protein binding, receptor binding, serine-type endopeptidase activity, thrombospondin receptor activity Human F2R BHF-UCL UniProtKB {GO:0005515=PMID:17848177, GO:0031594=GO_REF:0000024, GO:0051928=GO_REF:0000024, GO:0009653=PMID:9701242, GO:0043524=GO_REF:0000024, GO:0045211=GO_REF:0000024, GO:0051482=GO_REF:0000024, GO:0032496=GO_REF:0000024, GO:0070374=GO_REF:0000024, GO:0043123=PMID:12761501, GO:2000484=PMID:17404307, GO:0031681=GO_REF:0000024, GO:0030335=PMID:9701242, GO:0051209=GO_REF:0000024, GO:0005794=PMID:7961693, GO:0004930=PMID:17848177, GO:0030168=PMID:9038223, GO:0014068=GO_REF:0000024, GO:0043280=PMID:10692450, GO:0032967=PMID:9639571, GO:0007186=GO_REF:0000024, GO:0005887=PMID:1672265, GO:0045893=PMID:17848177, GO:0051930=GO_REF:0000024, GO:0007260=PMID:10692450, GO:0008284=GO_REF:0000024, GO:0008285=PMID:10692450, GO:0005886=PMID:9038223, GO:0015057=PMID:1672265, GO:0035025=GO_REF:0000024, GO:0007262=PMID:10692450, GO:0007200=PMID:20164183, GO:0007204=GO_REF:0000024, GO:0007205=GO_REF:0000024, GO:0001965=GO_REF:0000024, GO:0000186=GO_REF:0000024, GO:0048873=GO_REF:0000024, GO:0006954=GO_REF:0000024, GO:0045907=GO_REF:0000024, GO:0007529=GO_REF:0000024, GO:0045987=GO_REF:0000024, GO:2000778=PMID:11447194, GO:0031094=PMID:9038223, GO:0051281=PMID:1672265, GO:0006919=PMID:10692450, GO:0005102=PMID:1672265, GO:0009611=PMID:9639571, GO:0002248=PMID:9639571, GO:0005576=Reactome:REACT_72, GO:0003105=GO_REF:0000024, GO:0046427=PMID:10692450, GO:0030193=PMID:17848177, GO:0030194=PMID:9038223, GO:0007596=Reactome:REACT_604, GO:0005901=PMID:17848177, GO:0060155=PMID:1672265, GO:1900134=GO_REF:0000024, GO:0043410=PMID:17848177, GO:0032651=GO_REF:0000024} P25116 Proteinase-activated receptor 1 protein 20100624 {GO:0005515=IPI, GO:0031594=ISS, GO:0051928=ISS, GO:0009653=TAS, GO:0043524=ISS, GO:0045211=ISS, GO:0051482=ISS, GO:0032496=ISS, GO:0070374=ISS, GO:0043123=IEP, GO:2000484=IDA, GO:0031681=ISS, GO:0030335=IMP, GO:0051209=ISS, GO:0005794=TAS, GO:0004930=TAS, GO:0030168=IDA, GO:0014068=ISS, GO:0043280=IDA, GO:0032967=IDA, GO:0007186=ISS, GO:0005887=TAS, GO:0045893=IDA, GO:0051930=ISS, GO:0007260=IDA, GO:0008284=ISS, GO:0008285=IDA, GO:0005886=IDA, GO:0015057=IDA, GO:0035025=ISS, GO:0007262=IDA, GO:0007200=IDA, GO:0007204=ISS, GO:0007205=ISS, GO:0001965=ISS, GO:0000186=ISS, GO:0048873=ISS, GO:0006954=ISS, GO:0045907=ISS, GO:0007529=ISS, GO:0045987=ISS, GO:2000778=IDA, GO:0031094=IDA, GO:0051281=IDA, GO:0006919=IDA, GO:0005102=IPI, GO:0009611=IDA, GO:0002248=IDA, GO:0005576=TAS, GO:0003105=ISS, GO:0046427=IDA, GO:0030193=IDA, GO:0030194=IDA, GO:0007596=TAS, GO:0005901=IDA, GO:0060155=IC, GO:1900134=ISS, GO:0043410=IDA, GO:0032651=ISS} G-protein coupled receptor signaling pathway, STAT protein import into nucleus, activation of MAPKK activity, activation of cysteine-type endopeptidase activity involved in apoptotic process, anatomical structure morphogenesis, blood coagulation, connective tissue replacement involved in inflammatory response wound healing, elevation of cytosolic calcium ion concentration, elevation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway, establishment of synaptic specificity at neuromuscular junction, homeostasis of number of cells within a tissue, inflammatory response, negative regulation of cell proliferation, negative regulation of glomerular filtration, negative regulation of neuron apoptotic process, negative regulation of renin secretion into blood stream, phospholipase C-activating G-protein coupled receptor signaling pathway, platelet activation, platelet dense granule organization, positive regulation of ERK1 and ERK2 cascade, positive regulation of I-kappaB kinase/NF-kappaB cascade, positive regulation of JAK-STAT cascade, positive regulation of MAPK cascade, positive regulation of Rho protein signal transduction, positive regulation of blood coagulation, positive regulation of calcium ion transport, positive regulation of cell migration, positive regulation of cell proliferation, positive regulation of collagen biosynthetic process, positive regulation of cysteine-type endopeptidase activity involved in apoptotic process, positive regulation of interleukin-6 secretion, positive regulation of interleukin-8 secretion, positive regulation of phosphatidylinositol 3-kinase cascade, positive regulation of release of sequestered calcium ion into cytosol, positive regulation of smooth muscle contraction, positive regulation of transcription, DNA-dependent, positive regulation of vasoconstriction, protein kinase C-activating G-protein coupled receptor signaling pathway, regulation of blood coagulation, regulation of interleukin-1 beta production, regulation of sensory perception of pain, release of sequestered calcium ion into cytosol, response to lipopolysaccharide, response to wounding, tyrosine phosphorylation of STAT protein Golgi apparatus, caveola, extracellular region, integral to plasma membrane, neuromuscular junction, plasma membrane, platelet dense tubular network, postsynaptic membrane G-protein alpha-subunit binding, G-protein beta-subunit binding, G-protein coupled receptor activity, protein binding, receptor binding, thrombin receptor activity Human GO:0051281 F2RL1 BHF-UCL UniProtKB {GO:0005515=PMID:20826780, GO:0043311=PMID:11714832, GO:0070963=PMID:21501162, GO:0046330=PMID:11413129, GO:0050900=PMID:15155775, GO:0060100=PMID:21501162, GO:0046328=PMID:16410250, GO:0051607=PMID:19494303, GO:0046329=PMID:19781631, GO:0030836=PMID:17500066, GO:0031274=GO_REF:0000024, GO:0070374=GO_REF:0000024, GO:0043123=PMID:11413129, GO:0090195=PMID:19494303, GO:0043122=PMID:18453611, GO:0090198=PMID:19865078, GO:2000484=PMID:19865078, GO:0072608=PMID:18453611, GO:0031681=GO_REF:0000024, GO:0005794=PMID:8615752, GO:0030335=GO_REF:0000024, GO:0004930=PMID:18622013, GO:0050702=PMID:15155775, GO:0014068=GO_REF:0000024, GO:0010804=PMID:19781631, GO:0072643=GO_REF:0000024, GO:0007186=PMID:7556175, GO:0005887=PMID:17848177, GO:0045087=GO_REF:0000037, GO:0042119=PMID:15155775, GO:0034145=PMID:18622013, GO:0005886=Reactome:REACT_22436, GO:0034141=PMID:19865078, GO:0034140=PMID:19865078, GO:0015057=GO_REF:0000002, GO:0035025=GO_REF:0000024, GO:0035926=PMID:21501162, GO:0097029=GO_REF:0000024, GO:0007204=GO_REF:0000024, GO:0050927=PMID:17991872, GO:0031143=GO_REF:0000024, GO:0001965=GO_REF:0000024, GO:0006954=GO_REF:0000037, GO:0050921=GO_REF:0000024, GO:0061028=PMID:20826780, GO:0045909=GO_REF:0000024, GO:2000778=PMID:11447194, GO:0045944=PMID:16410250, GO:0004872=PMID:8615752, GO:0034137=PMID:19865078, GO:0032930=PMID:11714832, GO:0002286=GO_REF:0000024, GO:0005102=PMID:8615752, GO:0003104=GO_REF:0000024, GO:0002690=PMID:17991872, GO:0002741=PMID:11441110, GO:0030193=PMID:17848177, GO:0007596=GO_REF:0000002, GO:0070661=GO_REF:0000024, GO:0016021=GO_REF:0000002, GO:1900135=GO_REF:0000024} P55085 Proteinase-activated receptor 2 protein 20080215 {GO:0005515=IPI, GO:0043311=IDA, GO:0070963=IDA, GO:0046330=IDA, GO:0050900=IDA, GO:0060100=IDA, GO:0046328=IDA, GO:0051607=IDA, GO:0046329=IDA, GO:0030836=IDA, GO:0031274=ISS, GO:0070374=ISS, GO:0043123=IDA, GO:0090195=IDA, GO:0043122=IDA, GO:0090198=IDA, GO:2000484=IDA, GO:0072608=IDA, GO:0031681=ISS, GO:0005794=TAS, GO:0030335=ISS, GO:0004930=IMP, GO:0050702=IDA, GO:0014068=ISS, GO:0010804=IDA, GO:0072643=ISS, GO:0007186=TAS, GO:0005887=IDA, GO:0045087=IEA, GO:0042119=IDA, GO:0034145=IDA, GO:0005886=TAS, GO:0034141=IMP, GO:0034140=IMP, GO:0015057=IEA, GO:0035025=ISS, GO:0035926=IDA, GO:0097029=ISS, GO:0007204=ISS, GO:0050927=IDA, GO:0031143=ISS, GO:0001965=ISS, GO:0006954=IEA, GO:0050921=ISS, GO:0061028=IDA, GO:0045909=ISS, GO:2000778=IDA, GO:0045944=IDA, GO:0004872=TAS, GO:0034137=IMP, GO:0032930=IDA, GO:0002286=ISS, GO:0005102=TAS, GO:0003104=ISS, GO:0002690=IDA, GO:0002741=IDA, GO:0030193=IDA, GO:0007596=IEA, GO:0070661=ISS, GO:0016021=IEA, GO:1900135=ISS} G-protein coupled receptor signaling pathway, T cell activation involved in immune response, blood coagulation, chemokine (C-C motif) ligand 2 secretion, chemokine secretion, defense response to virus, elevation of cytosolic calcium ion concentration, establishment of endothelial barrier, inflammatory response, innate immune response, interferon-gamma secretion, interleukin-1 beta secretion, interleukin-10 secretion, leukocyte migration, leukocyte proliferation, mature dendritic cell differentiation, negative regulation of JNK cascade, negative regulation of chemokine secretion, negative regulation of toll-like receptor 3 signaling pathway, negative regulation of tumor necrosis factor-mediated signaling pathway, neutrophil activation, positive regulation of ERK1 and ERK2 cascade, positive regulation of I-kappaB kinase/NF-kappaB cascade, positive regulation of JNK cascade, positive regulation of Rho protein signal transduction, positive regulation of actin filament depolymerization, positive regulation of cell migration, positive regulation of chemotaxis, positive regulation of cytokine secretion involved in immune response, positive regulation of eosinophil degranulation, positive regulation of glomerular filtration, positive regulation of interleukin-6 secretion, positive regulation of interleukin-8 secretion, positive regulation of leukocyte chemotaxis, positive regulation of neutrophil mediated killing of gram-negative bacterium, positive regulation of phagocytosis, engulfment, positive regulation of phosphatidylinositol 3-kinase cascade, positive regulation of positive chemotaxis, positive regulation of pseudopodium assembly, positive regulation of renin secretion into blood stream, positive regulation of superoxide anion generation, positive regulation of toll-like receptor 2 signaling pathway, positive regulation of toll-like receptor 3 signaling pathway, positive regulation of toll-like receptor 4 signaling pathway, positive regulation of transcription from RNA polymerase II promoter, positive regulation of vasodilation, regulation of I-kappaB kinase/NF-kappaB cascade, regulation of JNK cascade, regulation of blood coagulation Golgi apparatus, integral to membrane, integral to plasma membrane, plasma membrane, pseudopodium G-protein alpha-subunit binding, G-protein beta-subunit binding, G-protein coupled receptor activity, protein binding, receptor activity, receptor binding, thrombin receptor activity Human F2RL2 IntAct UniProtKB {GO:0005515=PMID:17474147, GO:0016324=GO_REF:0000019, GO:0005886=Reactome:REACT_23902, GO:0007596=Reactome:REACT_604, GO:0005887=PMID:9087410, GO:0004435=PMID:9087410, GO:0015057=GO_REF:0000002, GO:0009611=PMID:9087410, GO:0030168=Reactome:REACT_798, GO:0005576=Reactome:REACT_72} O00254 Proteinase-activated receptor 3 protein 20130415 {GO:0005515=IPI, GO:0016324=IEA, GO:0005886=TAS, GO:0007596=TAS, GO:0005887=TAS, GO:0004435=TAS, GO:0015057=IEA, GO:0009611=TAS, GO:0030168=TAS, GO:0005576=TAS} blood coagulation, platelet activation, response to wounding apical plasma membrane, extracellular region, integral to plasma membrane, plasma membrane phosphatidylinositol phospholipase C activity, protein binding, thrombin receptor activity Human UniProtKB:P16333 F2RL3 BHF-UCL UniProtKB {GO:0007165=PMID:9618465, GO:0005886=Reactome:REACT_23902, GO:0005887=PMID:9618465, GO:0015057=GO_REF:0000002, GO:0007596=Reactome:REACT_604, GO:0009611=PMID:9618465, GO:0030168=Reactome:REACT_798, GO:0007200=PMID:9618465, GO:0060155=PMID:18480058, GO:0005576=Reactome:REACT_72, GO:0016021=GO_REF:0000002, GO:0051281=PMID:18480058} Q96RI0 Proteinase-activated receptor 4 protein 20100624 {GO:0007165=TAS, GO:0005886=TAS, GO:0005887=TAS, GO:0015057=IEA, GO:0007596=TAS, GO:0009611=TAS, GO:0030168=TAS, GO:0007200=TAS, GO:0060155=IC, GO:0005576=TAS, GO:0016021=IEA, GO:0051281=IDA} blood coagulation, phospholipase C-activating G-protein coupled receptor signaling pathway, platelet activation, platelet dense granule organization, positive regulation of release of sequestered calcium ion into cytosol, response to wounding, signal transduction extracellular region, integral to membrane, integral to plasma membrane, plasma membrane thrombin receptor activity Human GO:0051281 F3 BHF-UCL UniProtKB {GO:0005515=PMID:20634491, GO:0051897=PMID:18612547, GO:0043498=PMID:17898544, GO:0043066=PMID:18612547, GO:0030335=PMID:18612547, GO:0005886=Reactome:REACT_1669, GO:0006919=PMID:17898544, GO:0002543=PMID:17469850, GO:0002020=PMID:3455766, GO:0005615=PMID:19065458, GO:0045766=PMID:17898544, GO:0031233=PMID:17469850, GO:0050927=PMID:17991872, GO:0031012=PMID:2704749, GO:0005543=PMID:17469850, GO:0001938=PMID:17898544, GO:0007596=Reactome:REACT_2051, GO:0007598=Reactome:REACT_1573, GO:0002541=PMID:17469850, GO:0010641=PMID:17991872, GO:0016021=GO_REF:0000037} P13726 Tissue factor protein 20090416 {GO:0005515=IPI, GO:0051897=IMP, GO:0043498=IDA, GO:0043066=TAS, GO:0030335=TAS, GO:0005886=TAS, GO:0006919=IDA, GO:0002543=IC, GO:0002020=IPI, GO:0005615=IDA, GO:0045766=IDA, GO:0031233=IC, GO:0050927=IC, GO:0031012=IDA, GO:0005543=IDA, GO:0001938=IDA, GO:0007596=TAS, GO:0007598=TAS, GO:0002541=IDA, GO:0010641=IDA, GO:0016021=IEA} activation of blood coagulation via clotting cascade, activation of cysteine-type endopeptidase activity involved in apoptotic process, activation of plasma proteins involved in acute inflammatory response, blood coagulation, blood coagulation, extrinsic pathway, negative regulation of apoptotic process, positive regulation of angiogenesis, positive regulation of cell migration, positive regulation of endothelial cell proliferation, positive regulation of platelet-derived growth factor receptor signaling pathway, positive regulation of positive chemotaxis, positive regulation of protein kinase B signaling cascade extracellular matrix, extracellular space, integral to membrane, intrinsic to external side of plasma membrane, plasma membrane cell surface binding, phospholipid binding, protease binding, protein binding Human F5 Reactome UniProtKB {GO:0005515=PMID:9556620, GO:0005886=Reactome:REACT_1446, GO:0007596=Reactome:REACT_2051, GO:0005507=GO_REF:0000002, GO:0008015=GO_REF:0000019, GO:0002576=Reactome:REACT_318, GO:0030168=Reactome:REACT_798, GO:0031093=Reactome:REACT_21351, GO:0005576=Reactome:REACT_21351, GO:0007155=GO_REF:0000002, GO:0005615=GO_REF:0000019} P12259 Coagulation factor V protein 20040824 {GO:0005515=IPI, GO:0005886=TAS, GO:0007596=TAS, GO:0005507=IEA, GO:0008015=IEA, GO:0002576=TAS, GO:0030168=TAS, GO:0031093=TAS, GO:0005576=TAS, GO:0007155=IEA, GO:0005615=IEA} blood circulation, blood coagulation, cell adhesion, platelet activation, platelet degranulation extracellular region, extracellular space, plasma membrane, platelet alpha granule lumen copper ion binding, protein binding Human F7 BHF-UCL UniProtKB {GO:0051897=PMID:18612547, GO:0043627=GO_REF:0000019, GO:0004252=GO_REF:0000002, GO:0005886=Reactome:REACT_1669, GO:0031100=GO_REF:0000019, GO:0005615=GO_REF:0000019, GO:0050927=PMID:17991872, GO:0001948=PMID:3455766, GO:0006508=Reactome:REACT_733, GO:0010641=PMID:17991872, GO:0043066=PMID:18612547, GO:0060416=GO_REF:0000019, GO:0030335=PMID:18612547, GO:0005796=Reactome:REACT_1743, GO:0005509=GO_REF:0000002, GO:0005102=GO_REF:0000019, GO:0005576=Reactome:REACT_1669, GO:0031982=GO_REF:0000019, GO:0002690=PMID:17991872, GO:0017187=Reactome:REACT_1132, GO:0030194=GO_REF:0000019, GO:0007596=Reactome:REACT_2051, GO:0007598=Reactome:REACT_1573, GO:0008236=PMID:3037537, GO:0005788=Reactome:REACT_1969, GO:0007623=GO_REF:0000019, GO:0032571=GO_REF:0000019, GO:0044267=Reactome:REACT_17015, GO:0043687=Reactome:REACT_22161} P08709 Coagulation factor VII protein 20090416 {GO:0051897=IDA, GO:0043627=IEA, GO:0004252=IEA, GO:0005886=TAS, GO:0031100=IEA, GO:0005615=IEA, GO:0050927=IDA, GO:0001948=IPI, GO:0006508=TAS, GO:0010641=IDA, GO:0043066=TAS, GO:0060416=IEA, GO:0030335=TAS, GO:0005796=TAS, GO:0005509=IEA, GO:0005102=IEA, GO:0005576=TAS, GO:0031982=IEA, GO:0002690=IDA, GO:0017187=TAS, GO:0030194=IEA, GO:0007596=TAS, GO:0007598=TAS, GO:0008236=TAS, GO:0005788=TAS, GO:0007623=IEA, GO:0032571=IEA, GO:0044267=TAS, GO:0043687=TAS} blood coagulation, blood coagulation, extrinsic pathway, cellular protein metabolic process, circadian rhythm, negative regulation of apoptotic process, organ regeneration, peptidyl-glutamic acid carboxylation, positive regulation of blood coagulation, positive regulation of cell migration, positive regulation of leukocyte chemotaxis, positive regulation of platelet-derived growth factor receptor signaling pathway, positive regulation of positive chemotaxis, positive regulation of protein kinase B signaling cascade, post-translational protein modification, proteolysis, response to estrogen stimulus, response to growth hormone stimulus, response to vitamin K Golgi lumen, endoplasmic reticulum lumen, extracellular region, extracellular space, plasma membrane, vesicle calcium ion binding, glycoprotein binding, receptor binding, serine-type endopeptidase activity, serine-type peptidase activity Human F8 Reactome UniProtKB {GO:0005515=PMID:7756647, GO:0005886=Reactome:REACT_1668, GO:0005507=GO_REF:0000002, GO:0030168=Reactome:REACT_798, GO:0005576=Reactome:REACT_21351, GO:0006953=GO_REF:0000037, GO:0005615=GO_REF:0000039, GO:0007596=Reactome:REACT_2051, GO:0007597=Reactome:REACT_326, GO:0002576=Reactome:REACT_318, GO:0016491=GO_REF:0000002, GO:0031093=Reactome:REACT_21351, GO:0007155=GO_REF:0000002} P00451 Coagulation factor VIII protein 20050120 {GO:0005515=IPI, GO:0005886=TAS, GO:0005507=IEA, GO:0030168=TAS, GO:0005576=TAS, GO:0006953=IEA, GO:0005615=IEA, GO:0007596=TAS, GO:0007597=TAS, GO:0002576=TAS, GO:0016491=IEA, GO:0031093=TAS, GO:0007155=IEA} acute-phase response, blood coagulation, blood coagulation, intrinsic pathway, cell adhesion, platelet activation, platelet degranulation extracellular region, extracellular space, plasma membrane, platelet alpha granule lumen copper ion binding, oxidoreductase activity, protein binding Human F8A1 LIFEdb UniProtKB {GO:0008150=GO_REF:0000015, GO:0003674=GO_REF:0000015, GO:0005634=GO_REF:0000054} P23610 Factor VIII intron 22 protein protein 20100607 {GO:0008150=ND, GO:0003674=ND, GO:0005634=IDA} biological_process nucleus molecular_function Human F9 UniProtKB UniProtKB {GO:0004252=GO_REF:0000002, GO:0005886=Reactome:REACT_1668, GO:0005796=Reactome:REACT_618, GO:0005509=GO_REF:0000002, GO:0005576=GO_REF:0000002, GO:0017187=Reactome:REACT_1132, GO:0007596=GO_REF:0000002, GO:0007597=Reactome:REACT_326, GO:0007598=Reactome:REACT_1573, GO:0006508=GO_REF:0000038, GO:0005788=Reactome:REACT_2045, GO:0044267=Reactome:REACT_17015, GO:0043687=Reactome:REACT_22161} Q5FBE1 Coagulation factor IX protein 20130413 {GO:0004252=IEA, GO:0005886=TAS, GO:0005796=TAS, GO:0005509=IEA, GO:0005576=IEA, GO:0017187=TAS, GO:0007596=IEA, GO:0007597=TAS, GO:0007598=TAS, GO:0006508=IEA, GO:0005788=TAS, GO:0044267=TAS, GO:0043687=TAS} blood coagulation, blood coagulation, extrinsic pathway, blood coagulation, intrinsic pathway, cellular protein metabolic process, peptidyl-glutamic acid carboxylation, post-translational protein modification, proteolysis Golgi lumen, endoplasmic reticulum lumen, extracellular region, plasma membrane calcium ion binding, serine-type endopeptidase activity Human UniProtKB-KW:KW-0645 FA2H UniProtKB UniProtKB {GO:0006665=GO_REF:0000002, GO:0008219=GO_REF:0000037, GO:0042634=GO_REF:0000019, GO:0005506=GO_REF:0000002, GO:0005783=GO_REF:0000019, GO:0032287=GO_REF:0000019, GO:0046872=GO_REF:0000038, GO:0001949=GO_REF:0000019, GO:0032286=GO_REF:0000019, GO:0042127=GO_REF:0000019, GO:0005789=GO_REF:0000039, GO:0006633=GO_REF:0000037, GO:0016021=GO_REF:0000037, GO:0022900=GO_REF:0000037, GO:0030258=GO_REF:0000019, GO:0080132=GO_REF:0000019, GO:0020037=GO_REF:0000002} Q7L5A8 Fatty acid 2-hydroxylase protein 20130413 {GO:0006665=IEA, GO:0008219=IEA, GO:0042634=IEA, GO:0005506=IEA, GO:0005783=IEA, GO:0032287=IEA, GO:0046872=IEA, GO:0001949=IEA, GO:0032286=IEA, GO:0042127=IEA, GO:0005789=IEA, GO:0006633=IEA, GO:0016021=IEA, GO:0022900=IEA, GO:0030258=IEA, GO:0080132=IEA, GO:0020037=IEA} cell death, central nervous system myelin maintenance, electron transport chain, fatty acid biosynthetic process, lipid modification, peripheral nervous system myelin maintenance, regulation of cell proliferation, regulation of hair cycle, sebaceous gland cell differentiation, sphingolipid metabolic process endoplasmic reticulum, endoplasmic reticulum membrane, integral to membrane fatty acid alpha-hydroxylase activity, heme binding, iron ion binding, metal ion binding Human UniProtKB-SubCell:SL-0097 FAAH HPA UniProtKB {GO:0005737=GO_REF:0000052, GO:0016884=GO_REF:0000002, GO:0017064=PMID:9122178, GO:0031090=GO_REF:0000024, GO:0047372=GO_REF:0000019, GO:0016021=GO_REF:0000037, GO:0005856=GO_REF:0000039, GO:0009062=PMID:9122178, GO:0012505=GO_REF:0000039} O00519 Fatty-acid amide hydrolase 1 protein 20080205 {GO:0005737=IDA, GO:0016884=IEA, GO:0017064=IDA, GO:0031090=ISS, GO:0047372=IEA, GO:0016021=IEA, GO:0005856=IEA, GO:0009062=IDA, GO:0012505=IEA} fatty acid catabolic process cytoplasm, cytoskeleton, endomembrane system, integral to membrane, organelle membrane acylglycerol lipase activity, carbon-nitrogen ligase activity, with glutamine as amido-N-donor, fatty acid amide hydrolase activity Human FAAH2 UniProtKB UniProtKB {GO:0016884=GO_REF:0000002, GO:0016787=GO_REF:0000037, GO:0016021=GO_REF:0000037} Q6GMR7 Fatty-acid amide hydrolase 2 protein 20130413 {GO:0016884=IEA, GO:0016787=IEA, GO:0016021=IEA} integral to membrane carbon-nitrogen ligase activity, with glutamine as amido-N-donor, hydrolase activity Human UniProtKB-KW:KW-0378 FABP1 Reactome UniProtKB {GO:0005215=GO_REF:0000002, GO:0043066=PMID:16175609, GO:0005504=GO_REF:0000019, GO:0008284=GO_REF:0000019, GO:0032052=GO_REF:0000019, GO:0016209=PMID:16175609, GO:0070301=PMID:16175609, GO:0005782=GO_REF:0000024, GO:0051345=GO_REF:0000019, GO:0005324=GO_REF:0000019, GO:0071456=PMID:16175609, GO:0044281=Reactome:REACT_111217, GO:0008289=GO_REF:0000038, GO:0005829=GO_REF:0000019, GO:0050892=GO_REF:0000019, GO:0005543=GO_REF:0000019, GO:0045179=GO_REF:0000019, GO:0003682=GO_REF:0000019, GO:0008144=GO_REF:0000019, GO:0032000=GO_REF:0000019, GO:0005654=Reactome:REACT_115721, GO:0043154=PMID:16175609, GO:0044255=Reactome:REACT_22279} P07148 Fatty acid-binding protein, liver protein 20111113 {GO:0005215=IEA, GO:0043066=IDA, GO:0005504=IEA, GO:0008284=IEA, GO:0032052=IEA, GO:0016209=IDA, GO:0070301=IDA, GO:0005782=ISS, GO:0051345=IEA, GO:0005324=IEA, GO:0071456=IDA, GO:0044281=TAS, GO:0008289=IEA, GO:0005829=IEA, GO:0050892=IEA, GO:0005543=IEA, GO:0045179=IEA, GO:0003682=IEA, GO:0008144=IEA, GO:0032000=IEA, GO:0005654=TAS, GO:0043154=IDA, GO:0044255=TAS} cellular lipid metabolic process, cellular response to hydrogen peroxide, cellular response to hypoxia, intestinal absorption, negative regulation of apoptotic process, negative regulation of cysteine-type endopeptidase activity involved in apoptotic process, positive regulation of cell proliferation, positive regulation of fatty acid beta-oxidation, positive regulation of hydrolase activity, small molecule metabolic process apical cortex, cytosol, nucleoplasm, peroxisomal matrix antioxidant activity, bile acid binding, chromatin binding, drug binding, fatty acid binding, lipid binding, long-chain fatty acid transporter activity, phospholipid binding, transporter activity Human FABP2 PINC UniProtKB {GO:0005902=GO_REF:0000019, GO:0050892=GO_REF:0000019, GO:0005504=GO_REF:0000019, GO:0045179=GO_REF:0000019, GO:0005886=GO_REF:0000019, GO:0005324=GO_REF:0000019, GO:0007586=PMID:7883976, GO:0006631=GO_REF:0000019} P12104 Fatty acid-binding protein, intestinal protein 20030904 {GO:0005902=IEA, GO:0050892=IEA, GO:0005504=IEA, GO:0045179=IEA, GO:0005886=IEA, GO:0005324=IEA, GO:0007586=TAS, GO:0006631=IEA} digestion, fatty acid metabolic process, intestinal absorption apical cortex, microvillus, plasma membrane fatty acid binding, long-chain fatty acid transporter activity Human FABP3 PINC UniProtKB {GO:0008092=PMID:17987659, GO:0032868=GO_REF:0000019, GO:0016528=GO_REF:0000019, GO:0008285=PMID:7962070, GO:0070542=GO_REF:0000019, GO:0005324=GO_REF:0000019, GO:0042493=GO_REF:0000019, GO:0006631=GO_REF:0000019, GO:0050543=GO_REF:0000019, GO:0008289=PMID:3421901, GO:0005829=GO_REF:0000019} P05413 Fatty acid-binding protein, heart protein 20030904 {GO:0008092=IPI, GO:0032868=IEA, GO:0016528=IEA, GO:0008285=TAS, GO:0070542=IEA, GO:0005324=IEA, GO:0042493=IEA, GO:0006631=IEA, GO:0050543=IEA, GO:0008289=TAS, GO:0005829=IEA} fatty acid metabolic process, negative regulation of cell proliferation, response to drug, response to fatty acid, response to insulin stimulus cytosol, sarcoplasm cytoskeletal protein binding, icosatetraenoic acid binding, lipid binding, long-chain fatty acid transporter activity Human FABP4 HPA UniProtKB {GO:0006629=Reactome:REACT_602, GO:0042632=GO_REF:0000019, GO:0071285=GO_REF:0000019, GO:0005811=Reactome:REACT_27226, GO:0005215=GO_REF:0000002, GO:0005504=PMID:2481498, GO:0005634=GO_REF:0000039, GO:0044281=Reactome:REACT_111217, GO:0001816=GO_REF:0000019, GO:0005737=GO_REF:0000052, GO:0050872=GO_REF:0000019, GO:0050873=GO_REF:0000019, GO:0050729=GO_REF:0000019, GO:0019433=Reactome:REACT_494, GO:0006469=GO_REF:0000019, GO:0045892=GO_REF:0000019} P15090 Fatty acid-binding protein, adipocyte protein 20100326 {GO:0006629=TAS, GO:0042632=IEA, GO:0071285=IEA, GO:0005811=TAS, GO:0005215=IEA, GO:0005504=TAS, GO:0005634=IEA, GO:0044281=TAS, GO:0001816=IEA, GO:0005737=IDA, GO:0050872=IEA, GO:0050873=IEA, GO:0050729=IEA, GO:0019433=TAS, GO:0006469=IEA, GO:0045892=IEA} brown fat cell differentiation, cellular response to lithium ion, cholesterol homeostasis, cytokine production, lipid metabolic process, negative regulation of protein kinase activity, negative regulation of transcription, DNA-dependent, positive regulation of inflammatory response, small molecule metabolic process, triglyceride catabolic process, white fat cell differentiation cytoplasm, lipid particle, nucleus fatty acid binding, transporter activity Human FABP5 PINC UniProtKB {GO:0006629=PMID:8092987, GO:0005515=PMID:12839573, GO:0005215=GO_REF:0000002, GO:0005504=PMID:8092987, GO:0005737=PMID:16130169, GO:0008544=PMID:1512466, GO:0015758=GO_REF:0000019, GO:0006006=GO_REF:0000019, GO:0006656=GO_REF:0000019, GO:0008289=PMID:1512466} Q01469 Fatty acid-binding protein, epidermal protein 20030904 {GO:0006629=TAS, GO:0005515=IPI, GO:0005215=IEA, GO:0005504=TAS, GO:0005737=TAS, GO:0008544=TAS, GO:0015758=IEA, GO:0006006=IEA, GO:0006656=IEA, GO:0008289=TAS} epidermis development, glucose metabolic process, glucose transport, lipid metabolic process, phosphatidylcholine biosynthetic process cytoplasm fatty acid binding, lipid binding, protein binding, transporter activity Human FABP6 HPA UniProtKB {GO:0006629=PMID:9250612, GO:0005215=GO_REF:0000002, GO:0005737=PMID:7588781, GO:0005794=GO_REF:0000052, GO:0008285=PMID:9250612, GO:0015721=Reactome:REACT_11042, GO:0005634=GO_REF:0000052, GO:0008206=Reactome:REACT_11040, GO:0044281=Reactome:REACT_111217, GO:0005829=Reactome:REACT_10078, GO:0008289=GO_REF:0000037} P51161 Gastrotropin protein 20090616 {GO:0006629=NAS, GO:0005215=IEA, GO:0005737=TAS, GO:0005794=IDA, GO:0008285=TAS, GO:0015721=TAS, GO:0005634=IDA, GO:0008206=TAS, GO:0044281=TAS, GO:0005829=TAS, GO:0008289=IEA} bile acid and bile salt transport, bile acid metabolic process, lipid metabolic process, negative regulation of cell proliferation, small molecule metabolic process Golgi apparatus, cytoplasm, cytosol, nucleus lipid binding, transporter activity Human FABP9 ENSEMBL UniProtKB {GO:0001675=GO_REF:0000019, GO:0005215=GO_REF:0000002, GO:0001669=GO_REF:0000019, GO:0008289=GO_REF:0000037} Q0Z7S8 Fatty acid-binding protein 9 protein 20130413 {GO:0001675=IEA, GO:0005215=IEA, GO:0001669=IEA, GO:0008289=IEA} acrosome assembly acrosomal vesicle lipid binding, transporter activity Human Ensembl:ENSRNOP00000014949 FADD BHF-UCL UniProtKB {GO:0005515=PMID:16127453, GO:0008625=PMID:7538907, GO:0043005=GO_REF:0000019, GO:0034142=Reactome:REACT_6894, GO:0031265=PMID:20935634, GO:0031264=PMID:11101870, GO:0032813=PMID:21109225, GO:0097202=PMID:18387192, GO:0002020=PMID:9208847, GO:0051291=GO_REF:0000019, GO:0032757=PMID:16127453, GO:0042802=PMID:8681376, GO:0005829=Reactome:REACT_150447, GO:0002756=Reactome:REACT_6809, GO:0051607=PMID:21109225, GO:0045944=PMID:16127453, GO:0043123=PMID:12761501, GO:0034138=Reactome:REACT_6783, GO:0005164=GO_REF:0000019, GO:0070265=PMID:11101870, GO:0043065=PMID:20935634, GO:0032760=PMID:16127453, GO:0006919=Reactome:REACT_1503, GO:0006915=Reactome:REACT_578, GO:0005123=PMID:7538907, GO:0097191=PMID:18309324, GO:0002224=Reactome:REACT_6966, GO:0097190=PMID:11101870, GO:0045862=PMID:18387192, GO:0044297=GO_REF:0000019, GO:0045087=Reactome:REACT_6802, GO:0019048=GO_REF:0000037, GO:0060340=PMID:21109225, GO:0035666=Reactome:REACT_25281, GO:0045121=GO_REF:0000019, GO:0071260=PMID:19593445} Q13158 Protein FADD protein 20110310 {GO:0005515=IPI, GO:0008625=TAS, GO:0043005=IEA, GO:0034142=TAS, GO:0031265=IDA, GO:0031264=IDA, GO:0032813=IPI, GO:0097202=IDA, GO:0002020=IPI, GO:0051291=IEA, GO:0032757=IDA, GO:0042802=IPI, GO:0005829=TAS, GO:0002756=TAS, GO:0051607=IMP, GO:0045944=IDA, GO:0043123=IEP, GO:0034138=TAS, GO:0005164=IEA, GO:0070265=IMP, GO:0043065=IMP, GO:0032760=IDA, GO:0006919=TAS, GO:0006915=TAS, GO:0005123=TAS, GO:0097191=TAS, GO:0002224=TAS, GO:0097190=IDA, GO:0045862=IDA, GO:0044297=IEA, GO:0045087=TAS, GO:0019048=IEA, GO:0060340=IMP, GO:0035666=TAS, GO:0045121=IEA, GO:0071260=IEP} MyD88-independent toll-like receptor signaling pathway, TRIF-dependent toll-like receptor signaling pathway, activation of cysteine-type endopeptidase activity, activation of cysteine-type endopeptidase activity involved in apoptotic process, apoptotic process, apoptotic signaling pathway, cellular response to mechanical stimulus, defense response to virus, extrinsic apoptotic signaling pathway, extrinsic apoptotic signaling pathway via death domain receptors, innate immune response, necrotic cell death, positive regulation of I-kappaB kinase/NF-kappaB cascade, positive regulation of apoptotic process, positive regulation of interleukin-8 production, positive regulation of proteolysis, positive regulation of transcription from RNA polymerase II promoter, positive regulation of tumor necrosis factor production, positive regulation of type I interferon-mediated signaling pathway, protein heterooligomerization, toll-like receptor 3 signaling pathway, toll-like receptor 4 signaling pathway, toll-like receptor signaling pathway, virus-host interaction CD95 death-inducing signaling complex, cell body, cytosol, death-inducing signaling complex, membrane raft, neuron projection death receptor binding, identical protein binding, protease binding, protein binding, tumor necrosis factor receptor binding, tumor necrosis factor receptor superfamily binding Human FADS1 Reactome UniProtKB {GO:0006629=GO_REF:0000002, GO:0019369=GO_REF:0000019, GO:0046456=PMID:10601301, GO:0014070=GO_REF:0000019, GO:0033189=GO_REF:0000019, GO:0007267=PMID:10601301, GO:0005634=GO_REF:0000019, GO:0044281=Reactome:REACT_111217, GO:0043231=PMID:10601301, GO:0009744=GO_REF:0000019, GO:0044255=Reactome:REACT_22279, GO:0016717=GO_REF:0000019, GO:0009267=PMID:10601301, GO:0032868=GO_REF:0000019, GO:0006636=PMID:10601301, GO:0006355=PMID:10601301, GO:0005506=GO_REF:0000002, GO:0000248=PMID:10601301, GO:0007568=GO_REF:0000019, GO:0006950=GO_REF:0000019, GO:0036109=Reactome:REACT_121147, GO:0008654=PMID:10601301, GO:0043651=Reactome:REACT_121100, GO:0033559=Reactome:REACT_121284, GO:0016020=PMID:10601301, GO:0005789=Reactome:REACT_121259, GO:0016491=PMID:10601301, GO:0045595=PMID:10601301, GO:0016021=PMID:10601301, GO:0022900=GO_REF:0000037, GO:0020037=GO_REF:0000002} O60427 Fatty acid desaturase 1 protein 20130301 {GO:0006629=IEA, GO:0019369=IEA, GO:0046456=TAS, GO:0014070=IEA, GO:0033189=IEA, GO:0007267=NAS, GO:0005634=IEA, GO:0044281=TAS, GO:0043231=NAS, GO:0009744=IEA, GO:0044255=TAS, GO:0016717=IEA, GO:0009267=IDA, GO:0032868=IEA, GO:0006636=IDA, GO:0006355=NAS, GO:0005506=IEA, GO:0000248=TAS, GO:0007568=IEA, GO:0006950=IEA, GO:0036109=TAS, GO:0008654=TAS, GO:0043651=TAS, GO:0033559=TAS, GO:0016020=NAS, GO:0005789=TAS, GO:0016491=IDA, GO:0045595=NAS, GO:0016021=NAS, GO:0022900=IEA, GO:0020037=IEA} aging, alpha-linolenic acid metabolic process, arachidonic acid metabolic process, cell-cell signaling, cellular lipid metabolic process, cellular response to starvation, electron transport chain, icosanoid biosynthetic process, linoleic acid metabolic process, lipid metabolic process, phospholipid biosynthetic process, regulation of cell differentiation, regulation of transcription, DNA-dependent, response to insulin stimulus, response to organic cyclic compound, response to stress, response to sucrose stimulus, response to vitamin A, small molecule metabolic process, unsaturated fatty acid biosynthetic process, unsaturated fatty acid metabolic process endoplasmic reticulum membrane, integral to membrane, intracellular membrane-bounded organelle, membrane, nucleus C-5 sterol desaturase activity, heme binding, iron ion binding, oxidoreductase activity, oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water Human FADS2 Reactome UniProtKB {GO:0006629=GO_REF:0000002, GO:0006636=GO_REF:0000041, GO:0005506=GO_REF:0000002, GO:0004768=GO_REF:0000019, GO:0044281=Reactome:REACT_111217, GO:0036109=Reactome:REACT_121147, GO:0043651=Reactome:REACT_121100, GO:0033559=Reactome:REACT_121284, GO:0016020=PMID:9867867, GO:0005887=PMID:9867867, GO:0005789=Reactome:REACT_121304, GO:0006633=GO_REF:0000002, GO:0022900=GO_REF:0000037, GO:0016717=GO_REF:0000002, GO:0020037=GO_REF:0000002} O95864 Fatty acid desaturase 2 protein 20130301 {GO:0006629=IEA, GO:0006636=IEA, GO:0005506=IEA, GO:0004768=IEA, GO:0044281=TAS, GO:0036109=TAS, GO:0043651=TAS, GO:0033559=TAS, GO:0016020=TAS, GO:0005887=TAS, GO:0005789=TAS, GO:0006633=IEA, GO:0022900=IEA, GO:0016717=IEA, GO:0020037=IEA} alpha-linolenic acid metabolic process, electron transport chain, fatty acid biosynthetic process, linoleic acid metabolic process, lipid metabolic process, small molecule metabolic process, unsaturated fatty acid biosynthetic process, unsaturated fatty acid metabolic process endoplasmic reticulum membrane, integral to plasma membrane, membrane heme binding, iron ion binding, oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water, stearoyl-CoA 9-desaturase activity Human FADS3 UniProtKB UniProtKB {GO:0006629=GO_REF:0000002, GO:0003674=GO_REF:0000015, GO:0006636=PMID:10860662, GO:0016020=PMID:10860662, GO:0005506=GO_REF:0000002, GO:0005789=GO_REF:0000039, GO:0006633=GO_REF:0000002, GO:0016021=GO_REF:0000037, GO:0022900=GO_REF:0000037, GO:0016717=GO_REF:0000002, GO:0020037=GO_REF:0000002} Q9Y5Q0 Fatty acid desaturase 3 protein 20061026 {GO:0006629=IEA, GO:0003674=ND, GO:0006636=NAS, GO:0016020=NAS, GO:0005506=IEA, GO:0005789=IEA, GO:0006633=IEA, GO:0016021=IEA, GO:0022900=IEA, GO:0016717=IEA, GO:0020037=IEA} electron transport chain, fatty acid biosynthetic process, lipid metabolic process, unsaturated fatty acid biosynthetic process endoplasmic reticulum membrane, integral to membrane, membrane heme binding, iron ion binding, molecular_function, oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water Human FADS6 UniProtKB UniProtKB {GO:0006629=GO_REF:0000002, GO:0016491=GO_REF:0000037, GO:0006633=GO_REF:0000037, GO:0016021=GO_REF:0000037} Q8N9I5 Fatty acid desaturase 6 protein 20130413 {GO:0006629=IEA, GO:0016491=IEA, GO:0006633=IEA, GO:0016021=IEA} fatty acid biosynthetic process, lipid metabolic process integral to membrane oxidoreductase activity Human UniProtKB-KW:KW-0560 FAF1 GOC UniProtKB {GO:0045859=PMID:11713579, GO:0005515=PMID:15688372, GO:0043130=PMID:18775313, GO:0008219=PMID:15743842, GO:0048471=PMID:11713579, GO:0043065=PMID:10462485, GO:0019901=PMID:11713579, GO:0051059=PMID:14600157, GO:0042176=PMID:15743842, GO:0031265=PMID:12702723, GO:0019904=GO_REF:0000019, GO:0007253=PMID:14600157, GO:0006915=GO_REF:0000037, GO:0005634=PMID:15596450, GO:0005635=GO_REF:0000019, GO:0030155=GO_REF:0000019, GO:0005829=PMID:15596450, GO:0019887=PMID:11713579, GO:0031334=PMID:15688372, GO:0031072=PMID:15596450, GO:0043161=PMID:15743842, GO:0034098=PMID:18775313, GO:0031625=PMID:18775313} Q9UNN5 FAS-associated factor 1 protein 20130413 {GO:0045859=NAS, GO:0005515=IPI, GO:0043130=IDA, GO:0008219=IMP, GO:0048471=IDA, GO:0043065=NAS, GO:0019901=IDA, GO:0051059=IPI, GO:0042176=IMP, GO:0031265=NAS, GO:0019904=IEA, GO:0007253=IMP, GO:0006915=IEA, GO:0005634=IDA, GO:0005635=IEA, GO:0030155=IEA, GO:0005829=IDA, GO:0019887=NAS, GO:0031334=IMP, GO:0031072=IDA, GO:0043161=NAS, GO:0034098=IDA, GO:0031625=IDA} apoptotic process, cell death, cytoplasmic sequestering of NF-kappaB, positive regulation of apoptotic process, positive regulation of protein complex assembly, proteasomal ubiquitin-dependent protein catabolic process, regulation of cell adhesion, regulation of protein catabolic process, regulation of protein kinase activity CD95 death-inducing signaling complex, Cdc48p-Npl4p-Ufd1p AAA ATPase complex, cytosol, nuclear envelope, nucleus, perinuclear region of cytoplasm NF-kappaB binding, heat shock protein binding, protein binding, protein domain specific binding, protein kinase binding, protein kinase regulator activity, ubiquitin binding, ubiquitin protein ligase binding Human FAF2 BHF-UCL UniProtKB {GO:0005515=PMID:19818707, GO:0006986=GO_REF:0000037, GO:0043130=PMID:18775313, GO:0034098=PMID:18775313, GO:0031625=PMID:18775313} Q96CS3 FAS-associated factor 2 protein 20110707 {GO:0005515=IPI, GO:0006986=IEA, GO:0043130=IDA, GO:0034098=IDA, GO:0031625=IDA} response to unfolded protein Cdc48p-Npl4p-Ufd1p AAA ATPase complex protein binding, ubiquitin binding, ubiquitin protein ligase binding Human FAH Reactome UniProtKB {GO:0004334=Reactome:REACT_1297, GO:0034641=Reactome:REACT_13, GO:0006559=Reactome:REACT_1786, GO:0009072=GO_REF:0000002, GO:0044281=Reactome:REACT_111217, GO:0006572=GO_REF:0000037, GO:0006527=GO_REF:0000019, GO:0046872=GO_REF:0000037, GO:0005829=Reactome:REACT_1297} P16930 Fumarylacetoacetase protein 20130213 {GO:0004334=EXP, GO:0034641=TAS, GO:0006559=TAS, GO:0009072=IEA, GO:0044281=TAS, GO:0006572=IEA, GO:0006527=IEA, GO:0046872=IEA, GO:0005829=TAS} L-phenylalanine catabolic process, arginine catabolic process, aromatic amino acid family metabolic process, cellular nitrogen compound metabolic process, small molecule metabolic process, tyrosine catabolic process cytosol fumarylacetoacetase activity, metal ion binding Human FAHD1 LIFEdb UniProtKB {GO:0005739=GO_REF:0000054, GO:0047621=GO_REF:0000003, GO:0018773=PMID:21878618, GO:0034545=PMID:21878618, GO:0046872=GO_REF:0000037, GO:0005829=PMID:21878618} Q6P587 Acylpyruvase FAHD1, mitochondrial protein 20100607 {GO:0005739=IDA, GO:0047621=IEA, GO:0018773=IDA, GO:0034545=IDA, GO:0046872=IEA, GO:0005829=IDA} cytosol, mitochondrion acetylpyruvate hydrolase activity, acylpyruvate hydrolase activity, fumarylpyruvate hydrolase activity, metal ion binding Human FAHD2A UniProtKB UniProtKB {GO:0016787=GO_REF:0000037, GO:0003824=GO_REF:0000002, GO:0046872=GO_REF:0000037} Q96GK7 Fumarylacetoacetate hydrolase domain-containing protein 2A protein 20130413 {GO:0016787=IEA, GO:0003824=IEA, GO:0046872=IEA} catalytic activity, hydrolase activity, metal ion binding Human UniProtKB-KW:KW-0479 FAHD2B UniProtKB UniProtKB {GO:0016787=GO_REF:0000037, GO:0046872=GO_REF:0000037} Q6P2I3 Fumarylacetoacetate hydrolase domain-containing protein 2B protein 20130413 {GO:0016787=IEA, GO:0046872=IEA} hydrolase activity, metal ion binding Human UniProtKB-KW:KW-0479 FAIM UniProtKB UniProtKB {GO:0005737=GO_REF:0000039, GO:0043066=GO_REF:0000002, GO:0006915=GO_REF:0000037} Q9NVQ4 Fas apoptotic inhibitory molecule 1 protein 20130413 {GO:0005737=IEA, GO:0043066=IEA, GO:0006915=IEA} apoptotic process, negative regulation of apoptotic process cytoplasm Human UniProtKB-SubCell:SL-0086 FAIM2 UniProtKB UniProtKB {GO:0043066=PMID:10535980, GO:0030054=GO_REF:0000037, GO:0005886=GO_REF:0000039, GO:0006915=GO_REF:0000037, GO:0021549=GO_REF:0000024, GO:0005575=GO_REF:0000015, GO:0043523=PMID:17635665, GO:0021702=GO_REF:0000024, GO:0021680=GO_REF:0000024, GO:0021681=GO_REF:0000024, GO:0045211=GO_REF:0000039, GO:0045121=PMID:17635665, GO:0016021=GO_REF:0000037} Q9BWQ8 Protein lifeguard 2 protein 20120116 {GO:0043066=NAS, GO:0030054=IEA, GO:0005886=IEA, GO:0006915=IEA, GO:0021549=ISS, GO:0005575=ND, GO:0043523=IMP, GO:0021702=ISS, GO:0021680=ISS, GO:0021681=ISS, GO:0045211=IEA, GO:0045121=IDA, GO:0016021=IEA} apoptotic process, cerebellar Purkinje cell differentiation, cerebellar Purkinje cell layer development, cerebellar granular layer development, cerebellum development, negative regulation of apoptotic process, regulation of neuron apoptotic process cell junction, cellular_component, integral to membrane, membrane raft, plasma membrane, postsynaptic membrane Human UniProtKB:Q8K097 FAIM3 PINC UniProtKB {GO:0006968=PMID:9586636, GO:0043066=PMID:9586636, GO:0005576=GO_REF:0000039, GO:0016021=GO_REF:0000037} O60667 Fas apoptotic inhibitory molecule 3 protein 20040128 {GO:0006968=TAS, GO:0043066=TAS, GO:0005576=IEA, GO:0016021=IEA} cellular defense response, negative regulation of apoptotic process extracellular region, integral to membrane Human FAM101A null null {} null null null null {} null null null FAM101B MGI UniProtKB {GO:0030036=GO_REF:0000019, GO:0031005=PMID:21709252, GO:0001837=GO_REF:0000019, GO:0015629=GO_REF:0000019} Q8N5W9 Protein FAM101B protein 20120411 {GO:0030036=IEA, GO:0031005=IDA, GO:0001837=IEA, GO:0015629=IEA} actin cytoskeleton organization, epithelial to mesenchymal transition actin cytoskeleton filamin binding Human FAM102A null null {} null null null null {} null null null FAM102B null null {} null null null null {} null null null FAM103A1 UniProtKB UniProtKB {GO:0005515=PMID:22099306, GO:0003723=PMID:22099306, GO:0036031=PMID:22099306, GO:0006370=PMID:22099306, GO:0005634=PMID:22099306, GO:0032259=PMID:22099306, GO:0005845=PMID:22099306} Q9BTL3 RNMT-activating mini protein protein 20111125 {GO:0005515=IPI, GO:0003723=IDA, GO:0036031=IDA, GO:0006370=IDA, GO:0005634=IDA, GO:0032259=IMP, GO:0005845=IDA} 7-methylguanosine mRNA capping, methylation, recruitment of mRNA capping enzyme to RNA polymerase II holoenzyme complex mRNA cap binding complex, nucleus RNA binding, protein binding Human FAM104B null null {} null null null null {} null null null FAM105A null null {} null null null null {} null null null FAM105B null null {} null null null null {} null null null FAM107A UniProtKB UniProtKB {GO:0003674=GO_REF:0000015, GO:0005634=PMID:10564580, GO:0001558=PMID:10564580} O95990 Protein FAM107A protein 20031105 {GO:0003674=ND, GO:0005634=IDA, GO:0001558=IDA} regulation of cell growth nucleus molecular_function Human FAM107B null null {} null null null null {} null null null FAM109A UniProtKB UniProtKB {GO:0005802=PMID:21233288, GO:0005515=PMID:21233288, GO:0005794=GO_REF:0000039, GO:0005543=GO_REF:0000002, GO:0001881=PMID:21233288, GO:0030136=PMID:21233288, GO:0042147=PMID:21233288, GO:0007032=PMID:21233288, GO:0055037=PMID:21233288, GO:0005769=PMID:21233288, GO:0042803=PMID:21233288} Q8N4B1 Sesquipedalian-1 protein 20110427 {GO:0005802=IDA, GO:0005515=IPI, GO:0005794=IEA, GO:0005543=IEA, GO:0001881=IMP, GO:0030136=IDA, GO:0042147=IMP, GO:0007032=IMP, GO:0055037=IDA, GO:0005769=IDA, GO:0042803=IPI} endosome organization, receptor recycling, retrograde transport, endosome to Golgi Golgi apparatus, clathrin-coated vesicle, early endosome, recycling endosome, trans-Golgi network phospholipid binding, protein binding, protein homodimerization activity Human FAM109B UniProtKB UniProtKB {GO:0005802=PMID:21233288, GO:0005515=PMID:21233288, GO:0005794=GO_REF:0000039, GO:0005543=GO_REF:0000002, GO:0001881=PMID:21233288, GO:0030136=PMID:21233288, GO:0042147=PMID:21233288, GO:0007032=PMID:21233288, GO:0055037=PMID:21233288, GO:0005769=PMID:21233288, GO:0042803=PMID:21233288} Q6ICB4 Sesquipedalian-2 protein 20110427 {GO:0005802=IDA, GO:0005515=IPI, GO:0005794=IEA, GO:0005543=IEA, GO:0001881=IMP, GO:0030136=IDA, GO:0042147=IMP, GO:0007032=IMP, GO:0055037=IDA, GO:0005769=IDA, GO:0042803=IPI} endosome organization, receptor recycling, retrograde transport, endosome to Golgi Golgi apparatus, clathrin-coated vesicle, early endosome, recycling endosome, trans-Golgi network phospholipid binding, protein binding, protein homodimerization activity Human FAM110A IntAct UniProtKB {GO:0005515=PMID:17474147, GO:0005737=GO_REF:0000039, GO:0000922=GO_REF:0000039, GO:0005815=GO_REF:0000039} Q9BQ89 Protein FAM110A protein 20130415 {GO:0005515=IPI, GO:0005737=IEA, GO:0000922=IEA, GO:0005815=IEA} cytoplasm, microtubule organizing center, spindle pole protein binding Human UniProtKB:P16333 FAM110B HPA UniProtKB {GO:0005739=GO_REF:0000052, GO:0005737=GO_REF:0000052, GO:0005815=GO_REF:0000039, GO:0005634=GO_REF:0000052} Q8TC76 Protein FAM110B protein 20080205 {GO:0005739=IDA, GO:0005737=IDA, GO:0005815=IEA, GO:0005634=IDA} cytoplasm, microtubule organizing center, mitochondrion, nucleus Human FAM110C UniProtKB UniProtKB {GO:0051897=PMID:19698782, GO:0000922=GO_REF:0000039, GO:0030335=PMID:19698782, GO:0005815=GO_REF:0000039, GO:0043014=PMID:19698782, GO:0005874=GO_REF:0000037, GO:0060491=PMID:19698782, GO:0005634=GO_REF:0000039, GO:0005938=PMID:19698782} Q1W6H9 Protein FAM110C protein 20130307 {GO:0051897=IMP, GO:0000922=IEA, GO:0030335=IMP, GO:0005815=IEA, GO:0043014=IDA, GO:0005874=IEA, GO:0060491=IMP, GO:0005634=IEA, GO:0005938=IDA} positive regulation of cell migration, positive regulation of protein kinase B signaling cascade, regulation of cell projection assembly cell cortex, microtubule, microtubule organizing center, nucleus, spindle pole alpha-tubulin binding Human FAM111A UniProtKB UniProtKB {GO:0005515=PMID:23093934, GO:0005737=PMID:23093934, GO:0000087=PMID:23093934, GO:0005634=PMID:23093934, GO:0003824=GO_REF:0000002, GO:0045071=PMID:23093934} Q96PZ2 Protein FAM111A protein 20130326 {GO:0005515=IPI, GO:0005737=IDA, GO:0000087=IEP, GO:0005634=IDA, GO:0003824=IEA, GO:0045071=IMP} M phase of mitotic cell cycle, negative regulation of viral genome replication cytoplasm, nucleus catalytic activity, protein binding Human FAM111B InterPro UniProtKB {GO:0003824=GO_REF:0000002} Q6SJ93 Protein FAM111B protein 20130413 {GO:0003824=IEA} catalytic activity Human InterPro:IPR009003 FAM114A1 UniProtKB UniProtKB {GO:0005737=GO_REF:0000039} Q8IWE2 Protein NOXP20 protein 20130413 {GO:0005737=IEA} cytoplasm Human UniProtKB-SubCell:SL-0086 FAM114A2 UniProtKB UniProtKB {GO:0008150=GO_REF:0000015, GO:0017076=PMID:10843801, GO:0005575=GO_REF:0000015} Q9NRY5 Protein FAM114A2 protein 20061026 {GO:0008150=ND, GO:0017076=NAS, GO:0005575=ND} biological_process cellular_component purine nucleotide binding Human FAM115A null null {} null null null null {} null null null FAM117B null null {} null null null null {} null null null FAM118B null null {} null null null null {} null null null FAM120A HPA UniProtKB {GO:0005737=GO_REF:0000052, GO:0005886=GO_REF:0000039, GO:0003723=GO_REF:0000037} Q9NZB2 Constitutive coactivator of PPAR-gamma-like protein 1 protein 20101115 {GO:0005737=IDA, GO:0005886=IEA, GO:0003723=IEA} cytoplasm, plasma membrane RNA binding Human FAM120AOS null null {} null null null null {} null null null FAM120B UniProtKB UniProtKB {GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0030154=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q96EK7 Constitutive coactivator of peroxisome proliferator-activated receptor gamma protein 20130413 {GO:0006355=IEA, GO:0005634=IEA, GO:0030154=IEA, GO:0006351=IEA} cell differentiation, regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus Human UniProtKB-SubCell:SL-0191 FAM120C null null {} null null null null {} null null null FAM122A null null {} null null null null {} null null null FAM122B null null {} null null null null {} null null null FAM122C null null {} null null null null {} null null null FAM124A null null {} null null null null {} null null null FAM124B IntAct UniProtKB {GO:0005515=PMID:19447967} Q9H5Z6 Protein FAM124B protein 20130415 {GO:0005515=IPI} protein binding Human UniProtKB:Q99750 FAM126B LIFEdb UniProtKB {GO:0005622=GO_REF:0000054} Q8IXS8 Protein FAM126B protein 20100607 {GO:0005622=IDA} intracellular Human FAM127A UniProtKB UniProtKB {GO:0008150=GO_REF:0000015, GO:0005886=GO_REF:0000039, GO:0005575=GO_REF:0000015} O15255 CAAX box protein 1 protein 20061026 {GO:0008150=ND, GO:0005886=IEA, GO:0005575=ND} biological_process cellular_component, plasma membrane Human FAM127B null null {} null null null null {} null null null FAM127C null null {} null null null null {} null null null FAM129A HPA UniProtKB {GO:0003674=GO_REF:0000015, GO:0034976=GO_REF:0000024, GO:0005737=GO_REF:0000052, GO:0005886=GO_REF:0000052, GO:0005730=GO_REF:0000052, GO:0001934=GO_REF:0000024, GO:0001933=GO_REF:0000024, GO:0005634=GO_REF:0000052, GO:0045727=GO_REF:0000024} Q9BZQ8 Protein Niban protein 20101115 {GO:0003674=ND, GO:0034976=ISS, GO:0005737=IDA, GO:0005886=IDA, GO:0005730=IDA, GO:0001934=ISS, GO:0001933=ISS, GO:0005634=IDA, GO:0045727=ISS} negative regulation of protein phosphorylation, positive regulation of protein phosphorylation, positive regulation of translation, response to endoplasmic reticulum stress cytoplasm, nucleolus, nucleus, plasma membrane molecular_function Human FAM129B UniProtKB UniProtKB {GO:0043066=PMID:21148485, GO:0005543=GO_REF:0000002, GO:0005912=PMID:21148485, GO:0005634=PMID:21148485, GO:0005829=PMID:21148485} Q96TA1 Niban-like protein 1 protein 20110714 {GO:0043066=IMP, GO:0005543=IEA, GO:0005912=IDA, GO:0005634=IDA, GO:0005829=IDA} negative regulation of apoptotic process adherens junction, cytosol, nucleus phospholipid binding NOT Human FAM131A UniProtKB UniProtKB {GO:0005576=GO_REF:0000039} Q6UXB0 Protein FAM131A protein 20130413 {GO:0005576=IEA} extracellular region Human UniProtKB-SubCell:SL-0243 FAM131B null null {} null null null null {} null null null FAM131C null null {} null null null null {} null null null FAM133B null null {} null null null null {} null null null FAM134A UniProtKB UniProtKB {GO:0005783=GO_REF:0000002, GO:0016021=GO_REF:0000037} Q8NC44 Protein FAM134A protein 20130413 {GO:0005783=IEA, GO:0016021=IEA} endoplasmic reticulum, integral to membrane Human UniProtKB-KW:KW-0812 FAM134B UniProtKB UniProtKB {GO:0005801=GO_REF:0000024, GO:0005794=GO_REF:0000039, GO:0005783=GO_REF:0000002, GO:0016021=GO_REF:0000037, GO:0019233=PMID:19838196} Q9H6L5 Protein FAM134B protein 20091023 {GO:0005801=ISS, GO:0005794=IEA, GO:0005783=IEA, GO:0016021=IEA, GO:0019233=IMP} sensory perception of pain Golgi apparatus, cis-Golgi network, endoplasmic reticulum, integral to membrane Human UniProtKB:Q8VE91 FAM134C UniProtKB UniProtKB {GO:0016021=GO_REF:0000037} Q86VR2 Protein FAM134C protein 20130413 {GO:0016021=IEA} integral to membrane Human UniProtKB-KW:KW-0812 FAM135A null null {} null null null null {} null null null FAM135B null null {} null null null null {} null null null FAM136A LIFEdb UniProtKB {GO:0005739=GO_REF:0000039, GO:0005737=GO_REF:0000054} Q96C01 Protein FAM136A protein 20100607 {GO:0005739=IEA, GO:0005737=IDA} cytoplasm, mitochondrion Human FAM13A InterPro UniProtKB {GO:0005622=GO_REF:0000002, GO:0051056=Reactome:REACT_11051, GO:0007165=GO_REF:0000002, GO:0007264=Reactome:REACT_11044, GO:0005829=Reactome:REACT_9982, GO:0005096=GO_REF:0000037} Q6P521 Protein FAM13A protein 20130413 {GO:0005622=IEA, GO:0051056=TAS, GO:0007165=IEA, GO:0007264=TAS, GO:0005829=TAS, GO:0005096=IEA} regulation of small GTPase mediated signal transduction, signal transduction, small GTPase mediated signal transduction cytosol, intracellular GTPase activator activity Human InterPro:IPR000198|InterPro:IPR008936 FAM13B Reactome UniProtKB {GO:0005622=GO_REF:0000002, GO:0051056=Reactome:REACT_11051, GO:0007165=GO_REF:0000002, GO:0007264=Reactome:REACT_11044, GO:0005829=Reactome:REACT_9982, GO:0005096=GO_REF:0000037} Q9NYF5 Protein FAM13B protein 20130301 {GO:0005622=IEA, GO:0051056=TAS, GO:0007165=IEA, GO:0007264=TAS, GO:0005829=TAS, GO:0005096=IEA} regulation of small GTPase mediated signal transduction, signal transduction, small GTPase mediated signal transduction cytosol, intracellular GTPase activator activity Human FAM13C null null {} null null null null {} null null null FAM151A BHF-UCL UniProtKB {GO:0003674=GO_REF:0000015, GO:0008150=GO_REF:0000015, GO:0016020=PMID:12975309, GO:0016021=GO_REF:0000037} Q8WW52 Protein FAM151A protein 20090507 {GO:0003674=ND, GO:0008150=ND, GO:0016020=NAS, GO:0016021=IEA} biological_process integral to membrane, membrane molecular_function Human FAM153A null null {} null null null null {} null null null FAM154A null null {} null null null null {} null null null FAM156A LIFEdb UniProtKB {GO:0005635=GO_REF:0000054, GO:0016021=GO_REF:0000037} Q8NDB6 Protein FAM156A/FAM156B protein 20100607 {GO:0005635=IDA, GO:0016021=IEA} integral to membrane, nuclear envelope Human FAM160A2 UniProtKB UniProtKB {GO:0005515=PMID:18799622, GO:0008333=PMID:18799622, GO:0007032=PMID:18799622, GO:0045022=PMID:18799622, GO:0015031=GO_REF:0000037, GO:0007040=PMID:18799622, GO:0070695=PMID:18799622} Q8N612 FTS and Hook-interacting protein protein 20090603 {GO:0005515=IPI, GO:0008333=IMP, GO:0007032=IMP, GO:0045022=IMP, GO:0015031=IEA, GO:0007040=IMP, GO:0070695=IDA} early endosome to late endosome transport, endosome organization, endosome to lysosome transport, lysosome organization, protein transport FHF complex protein binding Human UniProtKB:Q9H8T0 FAM160B1 null null {} null null null null {} null null null FAM160B2 null null {} null null null null {} null null null FAM161A UniProtKB UniProtKB {GO:0005515=PMID:22940612, GO:0042384=PMID:22940612, GO:0005813=PMID:21399614, GO:0005737=GO_REF:0000037, GO:0032391=PMID:22940612, GO:0007601=GO_REF:0000037, GO:0036064=PMID:22940612, GO:0050896=GO_REF:0000037} Q3B820 Protein FAM161A protein 20121017 {GO:0005515=IPI, GO:0042384=IMP, GO:0005813=IDA, GO:0005737=IEA, GO:0032391=IDA, GO:0007601=IEA, GO:0036064=IDA, GO:0050896=IEA} cilium assembly, response to stimulus, visual perception centrosome, cilium basal body, cytoplasm, photoreceptor connecting cilium protein binding Human UniProtKB:Q86SQ7 FAM161B null null {} null null null null {} null null null FAM162A IntAct UniProtKB {GO:0005515=PMID:15082785, GO:0005739=GO_REF:0000039, GO:0043065=PMID:15082785, GO:0006919=PMID:15082785, GO:0090200=PMID:15082785, GO:0006927=PMID:15082785, GO:0071456=PMID:15082785, GO:0016021=GO_REF:0000037, GO:0051402=GO_REF:0000019} Q96A26 Protein FAM162A protein 20130415 {GO:0005515=IPI, GO:0005739=IEA, GO:0043065=IDA, GO:0006919=IDA, GO:0090200=IDA, GO:0006927=IDA, GO:0071456=IDA, GO:0016021=IEA, GO:0051402=IEA} activation of cysteine-type endopeptidase activity involved in apoptotic process, cellular response to hypoxia, neuron apoptotic process, positive regulation of apoptotic process, positive regulation of release of cytochrome c from mitochondria, transformed cell apoptotic process integral to membrane, mitochondrion protein binding Human UniProtKB:P45880 FAM168A null null {} null null null null {} null null null FAM168B UniProtKB UniProtKB {GO:0030424=GO_REF:0000039, GO:0048471=GO_REF:0000039, GO:0005886=GO_REF:0000039, GO:0016021=GO_REF:0000037} A1KXE4 Myelin-associated neurite-outgrowth inhibitor protein 20130413 {GO:0030424=IEA, GO:0048471=IEA, GO:0005886=IEA, GO:0016021=IEA} axon, integral to membrane, perinuclear region of cytoplasm, plasma membrane Human UniProtKB-SubCell:SL-0198 FAM169A UniProtKB UniProtKB {GO:0005637=GO_REF:0000039} Q9Y6X4 Soluble lamin-associated protein of 75 kDa protein 20130413 {GO:0005637=IEA} nuclear inner membrane Human UniProtKB-SubCell:SL-0179 FAM171A1 UniProtKB UniProtKB {GO:0016021=GO_REF:0000037} Q5VUB5 Protein FAM171A1 protein 20130413 {GO:0016021=IEA} integral to membrane Human UniProtKB-KW:KW-0812 FAM171A2 UniProtKB UniProtKB {GO:0016021=GO_REF:0000037} A8MVW0 Protein FAM171A2 protein 20130413 {GO:0016021=IEA} integral to membrane Human UniProtKB-KW:KW-0812 FAM171B UniProtKB UniProtKB {GO:0016021=GO_REF:0000037, GO:0003677=GO_REF:0000002} Q6P995 Protein FAM171B protein 20130413 {GO:0016021=IEA, GO:0003677=IEA} integral to membrane DNA binding Human UniProtKB-KW:KW-0812 FAM172A LIFEdb UniProtKB {GO:0005783=GO_REF:0000054, GO:0005576=GO_REF:0000039} Q8WUF8 Protein FAM172A protein 20100607 {GO:0005783=IDA, GO:0005576=IEA} endoplasmic reticulum, extracellular region Human FAM173A UniProtKB UniProtKB {GO:0016021=GO_REF:0000037} Q9BQD7 Protein FAM173A protein 20130413 {GO:0016021=IEA} integral to membrane Human UniProtKB-KW:KW-0812 FAM174A UniProtKB UniProtKB {GO:0016021=GO_REF:0000037} Q8TBP5 Membrane protein FAM174A protein 20130413 {GO:0016021=IEA} integral to membrane Human UniProtKB-KW:KW-0812 FAM174B UniProtKB UniProtKB {GO:0016021=GO_REF:0000037} Q3ZCQ3 Membrane protein FAM174B protein 20130413 {GO:0016021=IEA} integral to membrane Human UniProtKB-KW:KW-0812 FAM175A IntAct UniProtKB {GO:0005515=PMID:19615732, GO:0070531=PMID:17525340, GO:0010212=PMID:17643121, GO:0031572=PMID:17643121, GO:0005634=PMID:17643121, GO:0045739=PMID:17643121, GO:0031593=PMID:19261749, GO:0006302=PMID:17643121, GO:0016568=GO_REF:0000037} Q6UWZ7 BRCA1-A complex subunit Abraxas protein 20130415 {GO:0005515=IPI, GO:0070531=IDA, GO:0010212=IMP, GO:0031572=IMP, GO:0005634=IDA, GO:0045739=IMP, GO:0031593=IDA, GO:0006302=IMP, GO:0016568=IEA} G2 DNA damage checkpoint, chromatin modification, double-strand break repair, positive regulation of DNA repair, response to ionizing radiation BRCA1-A complex, nucleus polyubiquitin binding, protein binding Human UniProtKB:Q96RL1 FAM175B UniProtKB UniProtKB {GO:0070552=PMID:19214193, GO:0031593=PMID:19261749} Q15018 BRISC complex subunit Abro1 protein 20090422 {GO:0070552=IDA, GO:0031593=IDA} BRISC complex polyubiquitin binding Human FAM177A1 null null {} null null null null {} null null null FAM178A null null {} null null null null {} null null null FAM178B null null {} null null null null {} null null null FAM179B null null {} null null null null {} null null null FAM184A UniProtKB UniProtKB {GO:0003674=GO_REF:0000015, GO:0008150=GO_REF:0000015, GO:0005575=GO_REF:0000015} Q8NB25 Protein FAM184A protein 20101020 {GO:0003674=ND, GO:0008150=ND, GO:0005575=ND} biological_process cellular_component molecular_function Human FAM184B null null {} null null null null {} null null null FAM188A HPA UniProtKB {GO:0005515=PMID:21499297, GO:0031965=GO_REF:0000052, GO:0005509=GO_REF:0000002, GO:0005730=GO_REF:0000052, GO:0006915=GO_REF:0000037, GO:0005634=GO_REF:0000052} Q9H8M7 Protein FAM188A protein 20110516 {GO:0005515=IPI, GO:0031965=IDA, GO:0005509=IEA, GO:0005730=IDA, GO:0006915=IEA, GO:0005634=IDA} apoptotic process nuclear membrane, nucleolus, nucleus calcium ion binding, protein binding Human FAM189A2 UniProtKB UniProtKB {GO:0003674=GO_REF:0000015, GO:0008150=GO_REF:0000015, GO:0005575=GO_REF:0000015, GO:0016021=GO_REF:0000037} Q15884 Protein FAM189A2 protein 20061026 {GO:0003674=ND, GO:0008150=ND, GO:0005575=ND, GO:0016021=IEA} biological_process cellular_component, integral to membrane molecular_function Human FAM189B InterPro UniProtKB {GO:0005515=PMID:15064722, GO:0008150=GO_REF:0000015, GO:0050699=PMID:15064722, GO:0016021=GO_REF:0000002} Q96AD8 Protein FAM189B protein 20130413 {GO:0005515=IPI, GO:0008150=ND, GO:0050699=IPI, GO:0016021=IEA} biological_process integral to membrane WW domain binding, protein binding Human InterPro:IPR007237 FAM192A LIFEdb UniProtKB {GO:0005634=GO_REF:0000054} Q9GZU8 Protein FAM192A protein 20100607 {GO:0005634=IDA} nucleus Human FAM193B null null {} null null null null {} null null null FAM195A null null {} null null null null {} null null null FAM195B null null {} null null null null {} null null null FAM199X null null {} null null null null {} null null null FAM19A4 UniProtKB UniProtKB {GO:0005576=GO_REF:0000039} Q96LR4 Protein FAM19A4 protein 20130413 {GO:0005576=IEA} extracellular region Human UniProtKB-SubCell:SL-0243 FAM200A UniProtKB UniProtKB {GO:0016021=GO_REF:0000037, GO:0003676=GO_REF:0000002} Q8TCP9 Protein FAM200A protein 20130413 {GO:0016021=IEA, GO:0003676=IEA} integral to membrane nucleic acid binding Human UniProtKB-KW:KW-0812 FAM203A UniProtKB UniProtKB {GO:0008150=GO_REF:0000015, GO:0003674=GO_REF:0000015, GO:0005575=GO_REF:0000015} Q9BTY7 Protein FAM203A protein 20080604 {GO:0008150=ND, GO:0003674=ND, GO:0005575=ND} biological_process cellular_component molecular_function Human FAM206A InterPro UniProtKB {GO:0005960=GO_REF:0000002, GO:0006546=GO_REF:0000002} Q9NX38 Protein FAM206A protein 20130413 {GO:0005960=IEA, GO:0006546=IEA} glycine catabolic process glycine cleavage complex Human InterPro:IPR002930 FAM207A null null {} null null null null {} null null null FAM208A null null {} null null null null {} null null null FAM208B null null {} null null null null {} null null null FAM20B UniProtKB UniProtKB {GO:0005794=PMID:19473117, GO:0000139=GO_REF:0000039, GO:0016301=GO_REF:0000037, GO:0016773=PMID:19473117, GO:0016021=GO_REF:0000037, GO:0005524=GO_REF:0000037} O75063 Glycosaminoglycan xylosylkinase protein 20100514 {GO:0005794=IDA, GO:0000139=IEA, GO:0016301=IEA, GO:0016773=IDA, GO:0016021=IEA, GO:0005524=IEA} Golgi apparatus, Golgi membrane, integral to membrane ATP binding, kinase activity, phosphotransferase activity, alcohol group as acceptor Human FAM20C ENSEMBL UniProtKB {GO:0045669=GO_REF:0000019, GO:0001501=GO_REF:0000019, GO:0030501=GO_REF:0000019, GO:0097187=GO_REF:0000019, GO:0040036=GO_REF:0000019, GO:0004674=GO_REF:0000037, GO:0071895=GO_REF:0000019, GO:0070166=GO_REF:0000019, GO:0005509=GO_REF:0000019, GO:0051174=GO_REF:0000019, GO:0036179=GO_REF:0000019, GO:0005615=GO_REF:0000019} Q8IXL6 Extracellular serine/threonine protein kinase FAM20C protein 20130413 {GO:0045669=IEA, GO:0001501=IEA, GO:0030501=IEA, GO:0097187=IEA, GO:0040036=IEA, GO:0004674=IEA, GO:0071895=IEA, GO:0070166=IEA, GO:0005509=IEA, GO:0051174=IEA, GO:0036179=IEA, GO:0005615=IEA} dentinogenesis, enamel mineralization, odontoblast differentiation, osteoclast maturation, positive regulation of bone mineralization, positive regulation of osteoblast differentiation, regulation of fibroblast growth factor receptor signaling pathway, regulation of phosphorus metabolic process, skeletal system development extracellular space calcium ion binding, protein serine/threonine kinase activity Human Ensembl:ENSMUSP00000026972 FAM210A UniProtKB UniProtKB {GO:0005739=GO_REF:0000039, GO:0016021=GO_REF:0000037} Q96ND0 Protein FAM210A protein 20130413 {GO:0005739=IEA, GO:0016021=IEA} integral to membrane, mitochondrion Human UniProtKB-SubCell:SL-0173 FAM210B UniProtKB UniProtKB {GO:0016021=GO_REF:0000037} Q96KR6 Protein FAM210B protein 20130413 {GO:0016021=IEA} integral to membrane Human UniProtKB-KW:KW-0812 FAM212A ENSEMBL UniProtKB {GO:0021915=GO_REF:0000019} Q96EL1 Protein FAM212A protein 20130413 {GO:0021915=IEA} neural tube development Human Ensembl:ENSMUSP00000040433 FAM212B null null {} null null null null {} null null null FAM213A UniProtKB UniProtKB {GO:0005739=GO_REF:0000019, GO:0005737=PMID:19951071, GO:0016209=PMID:19951071, GO:0045670=PMID:19951071, GO:0055114=PMID:19951071} Q9BRX8 Redox-regulatory protein FAM213A protein 20110918 {GO:0005739=IEA, GO:0005737=IDA, GO:0016209=IDA, GO:0045670=IDA, GO:0055114=IDA} oxidation-reduction process, regulation of osteoclast differentiation cytoplasm, mitochondrion antioxidant activity Human FAM213B Reactome UniProtKB {GO:0019371=Reactome:REACT_150149, GO:0019369=Reactome:REACT_147851, GO:0001516=GO_REF:0000024, GO:0044281=Reactome:REACT_111217, GO:0016616=GO_REF:0000024, GO:0005829=GO_REF:0000039} Q8TBF2 Prostamide/prostaglandin F synthase protein 20130301 {GO:0019371=TAS, GO:0019369=TAS, GO:0001516=ISS, GO:0044281=TAS, GO:0016616=ISS, GO:0005829=IEA} arachidonic acid metabolic process, cyclooxygenase pathway, prostaglandin biosynthetic process, small molecule metabolic process cytosol oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor Human FAM214A null null {} null null null null {} null null null FAM214B LIFEdb UniProtKB {GO:0005634=GO_REF:0000054} Q7L5A3 Protein FAM214B protein 20100607 {GO:0005634=IDA} nucleus Human FAM21A UniProtKB UniProtKB {GO:0031901=GO_REF:0000039, GO:0071203=GO_REF:0000024, GO:0042147=GO_REF:0000024, GO:0005769=GO_REF:0000024} Q641Q2 WASH complex subunit FAM21A protein 20091127 {GO:0031901=IEA, GO:0071203=ISS, GO:0042147=ISS, GO:0005769=ISS} retrograde transport, endosome to Golgi WASH complex, early endosome, early endosome membrane Human UniProtKB:Q9Y4E1 FAM21B UniProtKB UniProtKB {GO:0031901=GO_REF:0000039, GO:0071203=GO_REF:0000024, GO:0042147=GO_REF:0000024, GO:0005769=GO_REF:0000024} Q5SNT6 WASH complex subunit FAM21B protein 20091127 {GO:0031901=IEA, GO:0071203=ISS, GO:0042147=ISS, GO:0005769=ISS} retrograde transport, endosome to Golgi WASH complex, early endosome, early endosome membrane Human UniProtKB:Q9Y4E1 FAM21C MGI UniProtKB {GO:0005515=PMID:19922874, GO:0005886=GO_REF:0000039, GO:0031901=GO_REF:0000039, GO:0071203=PMID:19922875, GO:0042147=PMID:19922874, GO:0005769=PMID:19922874, GO:0005768=PMID:20923837} Q9Y4E1 WASH complex subunit FAM21C protein 20120912 {GO:0005515=IPI, GO:0005886=IEA, GO:0031901=IEA, GO:0071203=IDA, GO:0042147=IMP, GO:0005769=IDA, GO:0005768=IDA} retrograde transport, endosome to Golgi WASH complex, early endosome, early endosome membrane, endosome, plasma membrane protein binding Human FAM26E UniProtKB UniProtKB {GO:0016021=GO_REF:0000037, GO:0006811=GO_REF:0000037} Q8N5C1 Protein FAM26E protein 20130413 {GO:0016021=IEA, GO:0006811=IEA} ion transport integral to membrane Human UniProtKB-KW:KW-0812 FAM27E3 null null {} null null null null {} null null null FAM32A LIFEdb UniProtKB {GO:0008150=GO_REF:0000015, GO:0003674=GO_REF:0000015, GO:0007049=GO_REF:0000037, GO:0005730=GO_REF:0000054, GO:0006915=GO_REF:0000037} Q9Y421 Protein FAM32A protein 20100607 {GO:0008150=ND, GO:0003674=ND, GO:0007049=IEA, GO:0005730=IDA, GO:0006915=IEA} apoptotic process, biological_process, cell cycle nucleolus molecular_function Human FAM35A null null {} null null null null {} null null null FAM3A UniProtKB UniProtKB {GO:0008150=GO_REF:0000015, GO:0003674=GO_REF:0000015, GO:0005576=GO_REF:0000039, GO:0005575=GO_REF:0000015} P98173 Protein FAM3A protein 20061026 {GO:0008150=ND, GO:0003674=ND, GO:0005576=IEA, GO:0005575=ND} biological_process cellular_component, extracellular region molecular_function Human FAM3B UniProtKB UniProtKB {GO:0006915=GO_REF:0000037, GO:0005576=PMID:12160727, GO:0005125=PMID:12160727, GO:0030073=PMID:12160727, GO:0005615=GO_REF:0000037} P58499 Protein FAM3B protein 20021105 {GO:0006915=IEA, GO:0005576=NAS, GO:0005125=NAS, GO:0030073=IDA, GO:0005615=IEA} apoptotic process, insulin secretion extracellular region, extracellular space cytokine activity Human FAM3C HPA UniProtKB {GO:0008150=GO_REF:0000015, GO:0005794=GO_REF:0000052, GO:0016023=GO_REF:0000039, GO:0005576=PMID:12160727, GO:0007275=GO_REF:0000037, GO:0005125=PMID:12160727} Q92520 Protein FAM3C protein 20120912 {GO:0008150=ND, GO:0005794=IDA, GO:0016023=IEA, GO:0005576=NAS, GO:0007275=IEA, GO:0005125=NAS} biological_process, multicellular organismal development Golgi apparatus, cytoplasmic membrane-bounded vesicle, extracellular region cytokine activity Human FAM43B null null {} null null null null {} null null null FAM45A null null {} null null null null {} null null null FAM46A null null {} null null null null {} null null null FAM46B null null {} null null null null {} null null null FAM46C null null {} null null null null {} null null null FAM46D null null {} null null null null {} null null null FAM47B null null {} null null null null {} null null null FAM49B ENSEMBL UniProtKB {GO:0005929=GO_REF:0000019} Q9NW21 Protein FAM49B protein 20130413 {GO:0005929=IEA} cilium Human Ensembl:ENSMUSP00000066359 FAM50A LIFEdb UniProtKB {GO:0003674=GO_REF:0000015, GO:0005634=GO_REF:0000054, GO:0007283=PMID:10534398} Q14320 Protein FAM50A protein 20100607 {GO:0003674=ND, GO:0005634=IDA, GO:0007283=NAS} spermatogenesis nucleus molecular_function Human FAM50B InterPro UniProtKB {GO:0005634=GO_REF:0000002} Q9Y247 Protein FAM50B protein 20130413 {GO:0005634=IEA} nucleus Human InterPro:IPR007005 FAM53A UniProtKB UniProtKB {GO:0005634=GO_REF:0000039} Q6NSI3 Protein FAM53A protein 20130413 {GO:0005634=IEA} nucleus Human UniProtKB-SubCell:SL-0191 FAM53B UniProtKB UniProtKB {GO:0008150=GO_REF:0000015, GO:0003674=GO_REF:0000015, GO:0005575=GO_REF:0000015} Q14153 Protein FAM53B protein 20061026 {GO:0008150=ND, GO:0003674=ND, GO:0005575=ND} biological_process cellular_component molecular_function Human FAM53C null null {} null null null null {} null null null FAM57A UniProtKB UniProtKB {GO:0005886=GO_REF:0000039, GO:0016021=GO_REF:0000037} Q8TBR7 Protein FAM57A protein 20130413 {GO:0005886=IEA, GO:0016021=IEA} integral to membrane, plasma membrane Human UniProtKB-SubCell:SL-0039 FAM58A UniProtKB UniProtKB {GO:0005515=PMID:18297069, GO:0006355=GO_REF:0000002, GO:0019901=GO_REF:0000002, GO:0000079=GO_REF:0000002} Q8N1B3 Cyclin-related protein FAM58A protein 20100114 {GO:0005515=IPI, GO:0006355=IEA, GO:0019901=IEA, GO:0000079=IEA} regulation of cyclin-dependent protein serine/threonine kinase activity, regulation of transcription, DNA-dependent protein binding, protein kinase binding Human UniProtKB:Q9NSC2 FAM5B UniProtKB UniProtKB {GO:0005576=GO_REF:0000039} Q9C0B6 Protein FAM5B protein 20130413 {GO:0005576=IEA} extracellular region Human UniProtKB-SubCell:SL-0243 FAM5C UniProtKB UniProtKB {GO:0005783=GO_REF:0000019, GO:0043025=GO_REF:0000019, GO:0005576=GO_REF:0000039, GO:0045786=GO_REF:0000019, GO:0030425=GO_REF:0000019, GO:0007399=GO_REF:0000019} Q76B58 Protein FAM5C protein 20130413 {GO:0005783=IEA, GO:0043025=IEA, GO:0005576=IEA, GO:0045786=IEA, GO:0030425=IEA, GO:0007399=IEA} negative regulation of cell cycle, nervous system development dendrite, endoplasmic reticulum, extracellular region, neuronal cell body Human UniProtKB-SubCell:SL-0243 FAM60A UniProtKB UniProtKB {GO:0030336=PMID:22984288, GO:0016580=PMID:22984288} Q9NP50 Protein FAM60A protein 20121018 {GO:0030336=IMP, GO:0016580=IDA} negative regulation of cell migration Sin3 complex Human FAM63A UniProtKB UniProtKB {GO:0008150=GO_REF:0000015, GO:0005575=GO_REF:0000015} Q8N5J2 Protein FAM63A protein 20081126 {GO:0008150=ND, GO:0005575=ND} biological_process cellular_component Human FAM63B UniProtKB UniProtKB {GO:0008150=GO_REF:0000015, GO:0003674=GO_REF:0000015, GO:0005575=GO_REF:0000015} Q8NBR6 Protein FAM63B protein 20081126 {GO:0008150=ND, GO:0003674=ND, GO:0005575=ND} biological_process cellular_component molecular_function Human FAM64A BHF-UCL UniProtKB {GO:0005515=PMID:16491119, GO:0005730=PMID:16491119} Q9BSJ6 Protein FAM64A protein 20100118 {GO:0005515=IPI, GO:0005730=IDA} nucleolus protein binding Human FAM65A UniProtKB UniProtKB {GO:0005737=GO_REF:0000024} Q6ZS17 Protein FAM65A protein 20110316 {GO:0005737=ISS} cytoplasm Human UniProtKB:Q68FE6 FAM65B UniProtKB UniProtKB {GO:0005739=GO_REF:0000039, GO:0007517=GO_REF:0000037, GO:0030175=GO_REF:0000039, GO:0005856=GO_REF:0000039, GO:0030154=GO_REF:0000037} Q9Y4F9 Protein FAM65B protein 20130413 {GO:0005739=IEA, GO:0007517=IEA, GO:0030175=IEA, GO:0005856=IEA, GO:0030154=IEA} cell differentiation, muscle organ development cytoskeleton, filopodium, mitochondrion Human UniProtKB-SubCell:SL-0286 FAM69B UniProtKB UniProtKB {GO:0005789=GO_REF:0000039, GO:0016021=GO_REF:0000037} Q5VUD6 Protein FAM69B protein 20130413 {GO:0005789=IEA, GO:0016021=IEA} endoplasmic reticulum membrane, integral to membrane Human UniProtKB-SubCell:SL-0097 FAM71C null null {} null null null null {} null null null FAM71E2 null null {} null null null null {} null null null FAM72A UniProtKB UniProtKB {GO:0005739=GO_REF:0000039} Q5TYM5 Protein FAM72A protein 20130413 {GO:0005739=IEA} mitochondrion Human UniProtKB-SubCell:SL-0173 FAM72B null null {} null null null null {} null null null FAM72D null null {} null null null null {} null null null FAM73A UniProtKB UniProtKB {GO:0016021=GO_REF:0000037} Q8NAN2 Protein FAM73A protein 20130413 {GO:0016021=IEA} integral to membrane Human UniProtKB-KW:KW-0812 FAM76A null null {} null null null null {} null null null FAM76B UniProtKB UniProtKB {GO:0016607=GO_REF:0000039} Q5HYJ3 Protein FAM76B protein 20130413 {GO:0016607=IEA} nuclear speck Human UniProtKB-SubCell:SL-0186 FAM78A null null {} null null null null {} null null null FAM81A null null {} null null null null {} null null null FAM83B null null {} null null null null {} null null null FAM83C null null {} null null null null {} null null null FAM83D UniProtKB UniProtKB {GO:0005737=GO_REF:0000039, GO:0000922=GO_REF:0000039, GO:0007067=GO_REF:0000037, GO:0051301=GO_REF:0000037} Q9H4H8 Protein FAM83D protein 20130413 {GO:0005737=IEA, GO:0000922=IEA, GO:0007067=IEA, GO:0051301=IEA} cell division, mitosis cytoplasm, spindle pole Human UniProtKB-SubCell:SL-0086 FAM83F null null {} null null null null {} null null null FAM83G null null {} null null null null {} null null null FAM83H UniProtKB UniProtKB {GO:0031214=GO_REF:0000037} Q6ZRV2 Protein FAM83H protein 20130413 {GO:0031214=IEA} biomineral tissue development Human UniProtKB-KW:KW-0091 FAM84B HGNC UniProtKB {GO:0005515=PMID:12477722, GO:0005737=PMID:12477722, GO:0005886=PMID:12477722} Q96KN1 Protein FAM84B protein 20050729 {GO:0005515=IPI, GO:0005737=IDA, GO:0005886=IDA} cytoplasm, plasma membrane protein binding Human FAM86A null null {} null null null null {} null null null FAM86B1 null null {} null null null null {} null null null FAM86B2 null null {} null null null null {} null null null FAM86C1 null null {} null null null null {} null null null FAM8A1 UniProtKB UniProtKB {GO:0016021=GO_REF:0000037} Q9UBU6 Protein FAM8A1 protein 20130413 {GO:0016021=IEA} integral to membrane Human UniProtKB-KW:KW-0812 FAM90A1 InterPro UniProtKB {GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002} Q86YD7 Protein FAM90A1 protein 20130413 {GO:0008270=IEA, GO:0003676=IEA} nucleic acid binding, zinc ion binding Human InterPro:IPR001878 FAM91A1 null null {} null null null null {} null null null FAM92A1 null null {} null null null null {} null null null FAM96A UniProtKB UniProtKB {GO:0008150=GO_REF:0000015, GO:0003674=GO_REF:0000015, GO:0005737=GO_REF:0000039, GO:0007059=GO_REF:0000037, GO:0005575=GO_REF:0000015, GO:0046872=GO_REF:0000037} Q9H5X1 MIP18 family protein FAM96A protein 20080829 {GO:0008150=ND, GO:0003674=ND, GO:0005737=IEA, GO:0007059=IEA, GO:0005575=ND, GO:0046872=IEA} biological_process, chromosome segregation cellular_component, cytoplasm metal ion binding, molecular_function Human FAM96B HPA UniProtKB {GO:0005515=PMID:20797633, GO:0005737=GO_REF:0000052, GO:0007059=PMID:20797633, GO:0097361=PMID:22678361, GO:0005730=GO_REF:0000052, GO:0005819=PMID:20797633, GO:0005634=GO_REF:0000052, GO:0044281=Reactome:REACT_111217, GO:0071817=PMID:20797633} Q9Y3D0 Mitotic spindle-associated MMXD complex subunit MIP18 protein 20111111 {GO:0005515=IPI, GO:0005737=IDA, GO:0007059=IMP, GO:0097361=IDA, GO:0005730=IDA, GO:0005819=IDA, GO:0005634=IDA, GO:0044281=TAS, GO:0071817=IDA} chromosome segregation, small molecule metabolic process CIA complex, MMXD complex, cytoplasm, nucleolus, nucleus, spindle protein binding Human FAM98A null null {} null null null null {} null null null FAM98B UniProtKB UniProtKB {GO:0072669=PMID:21311021} Q52LJ0 Protein FAM98B protein 20110222 {GO:0072669=IDA} tRNA-splicing ligase complex Human FAM98C null null {} null null null null {} null null null FAN1 UniProtKB UniProtKB {GO:0005515=PMID:20603016, GO:0043130=PMID:20603016, GO:0000287=PMID:20603016, GO:0008409=PMID:20603073, GO:0004528=GO_REF:0000003, GO:0006281=PMID:20603073, GO:0000724=PMID:20603016, GO:0005634=PMID:20603073, GO:0006289=PMID:20603016, GO:0017108=PMID:20603073, GO:0003677=GO_REF:0000002, GO:0033683=PMID:20603016} Q9Y2M0 Fanconi-associated nuclease 1 protein 20100721 {GO:0005515=IPI, GO:0043130=IDA, GO:0000287=TAS, GO:0008409=IDA, GO:0004528=IEA, GO:0006281=IMP, GO:0000724=IMP, GO:0005634=IDA, GO:0006289=IMP, GO:0017108=IDA, GO:0003677=IEA, GO:0033683=IMP} DNA repair, double-strand break repair via homologous recombination, nucleotide-excision repair, nucleotide-excision repair, DNA incision nucleus 5'-3' exonuclease activity, 5'-flap endonuclease activity, DNA binding, magnesium ion binding, phosphodiesterase I activity, protein binding, ubiquitin binding Human UniProtKB:Q9BXW9 FANCA BHF-UCL UniProtKB {GO:0005515=PMID:11726552, GO:0008585=GO_REF:0000019, GO:0005737=GO_REF:0000039, GO:0006281=Reactome:REACT_216, GO:0006461=PMID:9398857, GO:0042127=GO_REF:0000019, GO:0005634=PMID:11726552, GO:0005654=Reactome:REACT_18429, GO:0008584=GO_REF:0000019, GO:0043240=PMID:22343915, GO:0007140=GO_REF:0000019} O15360 Fanconi anemia group A protein protein 20110811 {GO:0005515=IPI, GO:0008585=IEA, GO:0005737=IEA, GO:0006281=TAS, GO:0006461=TAS, GO:0042127=IEA, GO:0005634=IDA, GO:0005654=TAS, GO:0008584=IEA, GO:0043240=IDA, GO:0007140=IEA} DNA repair, female gonad development, male gonad development, male meiosis, protein complex assembly, regulation of cell proliferation Fanconi anaemia nuclear complex, cytoplasm, nucleoplasm, nucleus protein binding Human FANCB Reactome UniProtKB {GO:0006281=Reactome:REACT_216, GO:0005654=Reactome:REACT_18429, GO:0043240=PMID:20347428} Q8NB91 Fanconi anemia group B protein protein 20130213 {GO:0006281=TAS, GO:0005654=TAS, GO:0043240=IDA} DNA repair Fanconi anaemia nuclear complex, nucleoplasm Human FANCC Reactome UniProtKB {GO:0005515=PMID:9596688, GO:0005737=PMID:9398857, GO:0006281=Reactome:REACT_216, GO:0006461=PMID:9398857, GO:0019430=GO_REF:0000019, GO:0005654=Reactome:REACT_18429, GO:0005634=PMID:9398857, GO:0006289=GO_REF:0000019, GO:0002262=GO_REF:0000019, GO:0007281=GO_REF:0000019, GO:0043240=PMID:22266823, GO:0005829=PMID:9596688} Q00597 Fanconi anemia group C protein protein 20130213 {GO:0005515=IPI, GO:0005737=TAS, GO:0006281=TAS, GO:0006461=TAS, GO:0019430=IEA, GO:0005654=TAS, GO:0005634=TAS, GO:0006289=IEA, GO:0002262=IEA, GO:0007281=IEA, GO:0043240=IDA, GO:0005829=IDA} DNA repair, germ cell development, myeloid cell homeostasis, nucleotide-excision repair, protein complex assembly, removal of superoxide radicals Fanconi anaemia nuclear complex, cytoplasm, cytosol, nucleoplasm, nucleus protein binding Human FANCD2 IntAct UniProtKB {GO:0005515=PMID:18212739, GO:0007129=GO_REF:0000019, GO:0000793=GO_REF:0000019, GO:0006281=Reactome:REACT_216, GO:0007276=GO_REF:0000019, GO:0005654=Reactome:REACT_18429, GO:0010332=PMID:12874027} Q9BXW9 Fanconi anemia group D2 protein protein 20130415 {GO:0005515=IPI, GO:0007129=IEA, GO:0000793=IEA, GO:0006281=TAS, GO:0007276=IEA, GO:0005654=TAS, GO:0010332=IDA} DNA repair, gamete generation, response to gamma radiation, synapsis condensed chromosome, nucleoplasm protein binding Human UniProtKB:P51587 FANCE Reactome UniProtKB {GO:0003674=GO_REF:0000015, GO:0006281=Reactome:REACT_216, GO:0005654=Reactome:REACT_18429, GO:0005634=PMID:11001585, GO:0043240=PMID:22266823} Q9HB96 Fanconi anemia group E protein protein 20130213 {GO:0003674=ND, GO:0006281=TAS, GO:0005654=TAS, GO:0005634=NAS, GO:0043240=IDA} DNA repair Fanconi anaemia nuclear complex, nucleoplasm, nucleus molecular_function Human FANCF IntAct UniProtKB {GO:0005515=PMID:12649160, GO:0003674=GO_REF:0000015, GO:0008150=GO_REF:0000015, GO:0006281=Reactome:REACT_216, GO:0005654=Reactome:REACT_18429, GO:0043240=PMID:20347428} Q9NPI8 Fanconi anemia group F protein protein 20130415 {GO:0005515=IPI, GO:0003674=ND, GO:0008150=ND, GO:0006281=TAS, GO:0005654=TAS, GO:0043240=IDA} DNA repair, biological_process Fanconi anaemia nuclear complex, nucleoplasm molecular_function, protein binding Human UniProtKB:O15360 FANCG IntAct UniProtKB {GO:0003684=PMID:9806548, GO:0005739=PMID:17060495, GO:0005515=PMID:16189514, GO:0009314=GO_REF:0000019, GO:0001541=GO_REF:0000019, GO:0006281=Reactome:REACT_216, GO:0007286=GO_REF:0000019, GO:0000075=PMID:9256465, GO:0005654=Reactome:REACT_18429, GO:0007005=PMID:17060495, GO:0006974=GO_REF:0000019, GO:0043240=PMID:22343915} O15287 Fanconi anemia group G protein protein 20130415 {GO:0003684=TAS, GO:0005739=IDA, GO:0005515=IPI, GO:0009314=IEA, GO:0001541=IEA, GO:0006281=TAS, GO:0007286=IEA, GO:0000075=TAS, GO:0005654=TAS, GO:0007005=IMP, GO:0006974=IEA, GO:0043240=IDA} DNA repair, cell cycle checkpoint, mitochondrion organization, ovarian follicle development, response to DNA damage stimulus, response to radiation, spermatid development Fanconi anaemia nuclear complex, mitochondrion, nucleoplasm damaged DNA binding, protein binding Human UniProtKB:O15360 FANCI HPA UniProtKB {GO:0005515=PMID:20603015, GO:0007049=GO_REF:0000037, GO:0006281=Reactome:REACT_216, GO:0005886=GO_REF:0000052, GO:0031398=PMID:18029348, GO:0005654=Reactome:REACT_18367, GO:0005634=GO_REF:0000052, GO:0003677=GO_REF:0000037} Q9NVI1 Fanconi anemia group I protein protein 20110516 {GO:0005515=IPI, GO:0007049=IEA, GO:0006281=TAS, GO:0005886=IDA, GO:0031398=IDA, GO:0005654=TAS, GO:0005634=IDA, GO:0003677=IEA} DNA repair, cell cycle, positive regulation of protein ubiquitination nucleoplasm, nucleus, plasma membrane DNA binding, protein binding Human FANCL Reactome UniProtKB {GO:0005737=GO_REF:0000039, GO:0004842=Reactome:REACT_18429, GO:0006513=PMID:16916645, GO:0006281=Reactome:REACT_216, GO:0007276=GO_REF:0000019, GO:0042127=GO_REF:0000019, GO:0005654=Reactome:REACT_18429, GO:0008270=GO_REF:0000002, GO:0005635=GO_REF:0000019, GO:0031625=PMID:19111657, GO:0006974=PMID:16916645, GO:0043240=PMID:22343915} Q9NW38 E3 ubiquitin-protein ligase FANCL protein 20130213 {GO:0005737=IEA, GO:0004842=TAS, GO:0006513=IDA, GO:0006281=TAS, GO:0007276=IEA, GO:0042127=IEA, GO:0005654=TAS, GO:0008270=IEA, GO:0005635=IEA, GO:0031625=IPI, GO:0006974=IMP, GO:0043240=IDA} DNA repair, gamete generation, protein monoubiquitination, regulation of cell proliferation, response to DNA damage stimulus Fanconi anaemia nuclear complex, cytoplasm, nuclear envelope, nucleoplasm ubiquitin protein ligase binding, ubiquitin-protein ligase activity, zinc ion binding Human FANCM Reactome UniProtKB {GO:0008026=GO_REF:0000002, GO:0005515=PMID:20347429, GO:0071821=PMID:20347428, GO:0006259=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0005524=GO_REF:0000037, GO:0043240=PMID:20347428, GO:0004518=GO_REF:0000002, GO:0006281=Reactome:REACT_216, GO:0003682=PMID:20347429, GO:0000712=PMID:20347428, GO:0031297=PMID:20347428, GO:0005654=Reactome:REACT_18429} Q8IYD8 Fanconi anemia group M protein protein 20130213 {GO:0008026=IEA, GO:0005515=IPI, GO:0071821=IDA, GO:0006259=IEA, GO:0003677=IEA, GO:0005524=IEA, GO:0043240=IDA, GO:0004518=IEA, GO:0006281=TAS, GO:0003682=IDA, GO:0000712=IMP, GO:0031297=IMP, GO:0005654=TAS} DNA metabolic process, DNA repair, replication fork processing, resolution of meiotic recombination intermediates FANCM-MHF complex, Fanconi anaemia nuclear complex, nucleoplasm ATP binding, ATP-dependent helicase activity, DNA binding, chromatin binding, nuclease activity, protein binding Human FANK1 HPA UniProtKB {GO:0005737=GO_REF:0000039, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052} Q8TC84 Fibronectin type 3 and ankyrin repeat domains protein 1 protein 20120912 {GO:0005737=IEA, GO:0005730=IDA, GO:0005634=IDA} cytoplasm, nucleolus, nucleus NOT Human FAP BHF-UCL UniProtKB {GO:0005515=PMID:16651416, GO:0030054=GO_REF:0000037, GO:0004252=GO_REF:0000002, GO:0031258=GO_REF:0000039, GO:0051917=PMID:17317851, GO:0002020=PMID:17317851, GO:0005615=PMID:17317851, GO:0010716=PMID:16651416, GO:0030027=PMID:16651416, GO:0042803=PMID:9247085, GO:0004175=PMID:17317851, GO:0016020=GO_REF:0000002, GO:0043542=PMID:16651416, GO:0071438=GO_REF:0000039, GO:0006508=GO_REF:0000037, GO:0046983=PMID:9065413, GO:0008236=PMID:9065413, GO:0008233=PMID:9688278, GO:0016021=PMID:9065413, GO:0008239=PMID:7911242, GO:0004222=PMID:9065413} Q12884 Seprase protein 20110203 {GO:0005515=IPI, GO:0030054=IEA, GO:0004252=IEA, GO:0031258=IEA, GO:0051917=IC, GO:0002020=IPI, GO:0005615=IDA, GO:0010716=IDA, GO:0030027=IDA, GO:0042803=NAS, GO:0004175=IDA, GO:0016020=IEA, GO:0043542=IDA, GO:0071438=IEA, GO:0006508=IEA, GO:0046983=NAS, GO:0008236=IMP, GO:0008233=IDA, GO:0016021=NAS, GO:0008239=NAS, GO:0004222=TAS} endothelial cell migration, negative regulation of extracellular matrix disassembly, proteolysis, regulation of fibrinolysis cell junction, extracellular space, integral to membrane, invadopodium membrane, lamellipodium, lamellipodium membrane, membrane dipeptidyl-peptidase activity, endopeptidase activity, metalloendopeptidase activity, peptidase activity, protease binding, protein binding, protein dimerization activity, protein homodimerization activity, serine-type endopeptidase activity, serine-type peptidase activity contributes_to Human FAR1 Reactome UniProtKB {GO:0005782=Reactome:REACT_17006, GO:0008611=Reactome:REACT_1407, GO:0044281=Reactome:REACT_111217, GO:0016021=GO_REF:0000037, GO:0035336=PMID:15220348, GO:0080019=PMID:15220348, GO:0044255=Reactome:REACT_16957, GO:0005778=PMID:21525035, GO:0050062=GO_REF:0000019, GO:0046474=PMID:20071337, GO:0010025=GO_REF:0000019, GO:0005777=PMID:20071337} Q8WVX9 Fatty acyl-CoA reductase 1 protein 20130301 {GO:0005782=TAS, GO:0008611=TAS, GO:0044281=TAS, GO:0016021=IEA, GO:0035336=IDA, GO:0080019=IDA, GO:0044255=TAS, GO:0005778=IDA, GO:0050062=IEA, GO:0046474=IDA, GO:0010025=IEA, GO:0005777=IDA} cellular lipid metabolic process, ether lipid biosynthetic process, glycerophospholipid biosynthetic process, long-chain fatty-acyl-CoA metabolic process, small molecule metabolic process, wax biosynthetic process integral to membrane, peroxisomal matrix, peroxisomal membrane, peroxisome fatty-acyl-CoA reductase (alcohol-forming) activity, long-chain-fatty-acyl-CoA reductase activity Human FAR2 Reactome UniProtKB {GO:0005782=Reactome:REACT_17042, GO:0008611=Reactome:REACT_1407, GO:0005789=GO_REF:0000039, GO:0044281=Reactome:REACT_111217, GO:0016021=GO_REF:0000037, GO:0035336=PMID:15220348, GO:0080019=PMID:15220348, GO:0044255=Reactome:REACT_16957, GO:0005778=GO_REF:0000039, GO:0050062=GO_REF:0000019, GO:0005777=GO_REF:0000024} Q96K12 Fatty acyl-CoA reductase 2 protein 20130301 {GO:0005782=TAS, GO:0008611=TAS, GO:0005789=IEA, GO:0044281=TAS, GO:0016021=IEA, GO:0035336=IDA, GO:0080019=IDA, GO:0044255=TAS, GO:0005778=IEA, GO:0050062=IEA, GO:0005777=ISS} cellular lipid metabolic process, ether lipid biosynthetic process, long-chain fatty-acyl-CoA metabolic process, small molecule metabolic process endoplasmic reticulum membrane, integral to membrane, peroxisomal matrix, peroxisomal membrane, peroxisome fatty-acyl-CoA reductase (alcohol-forming) activity, long-chain-fatty-acyl-CoA reductase activity Human FARP1 PINC UniProtKB {GO:0008092=GO_REF:0000002, GO:0035023=GO_REF:0000002, GO:0007416=GO_REF:0000024, GO:0030425=GO_REF:0000024, GO:0031234=GO_REF:0000024, GO:0005829=GO_REF:0000024, GO:0005622=GO_REF:0000002, GO:0048813=GO_REF:0000024, GO:0005737=GO_REF:0000002, GO:0005543=GO_REF:0000002, GO:0010923=PMID:19389623, GO:0005089=PMID:9425278, GO:0005856=GO_REF:0000002, GO:0030676=GO_REF:0000024, GO:0019898=GO_REF:0000002} Q9Y4F1 FERM, RhoGEF and pleckstrin domain-containing protein 1 protein 20030904 {GO:0008092=IEA, GO:0035023=IEA, GO:0007416=ISS, GO:0030425=ISS, GO:0031234=ISS, GO:0005829=ISS, GO:0005622=IEA, GO:0048813=ISS, GO:0005737=IEA, GO:0005543=IEA, GO:0010923=IDA, GO:0005089=TAS, GO:0005856=IEA, GO:0030676=ISS, GO:0019898=IEA} dendrite morphogenesis, negative regulation of phosphatase activity, regulation of Rho protein signal transduction, synapse assembly cytoplasm, cytoskeleton, cytosol, dendrite, extrinsic to internal side of plasma membrane, extrinsic to membrane, intracellular Rac guanyl-nucleotide exchange factor activity, Rho guanyl-nucleotide exchange factor activity, cytoskeletal protein binding, phospholipid binding Human FARP2 Reactome UniProtKB {GO:0008092=GO_REF:0000002, GO:0071800=GO_REF:0000024, GO:0031532=GO_REF:0000024, GO:0035023=GO_REF:0000002, GO:0030316=GO_REF:0000024, GO:0033623=GO_REF:0000024, GO:0005829=Reactome:REACT_19403, GO:0016322=PMID:12351724, GO:0005622=GO_REF:0000002, GO:0016601=PMID:12351724, GO:0005737=PMID:12351724, GO:0005543=GO_REF:0000002, GO:0007411=Reactome:REACT_18266, GO:0071526=GO_REF:0000024, GO:0005089=PMID:12351724, GO:0007155=GO_REF:0000024, GO:0005856=GO_REF:0000002, GO:0030676=GO_REF:0000024, GO:0019898=GO_REF:0000002} O94887 FERM, RhoGEF and pleckstrin domain-containing protein 2 protein 20090515 {GO:0008092=IEA, GO:0071800=ISS, GO:0031532=ISS, GO:0035023=IEA, GO:0030316=ISS, GO:0033623=ISS, GO:0005829=TAS, GO:0016322=IDA, GO:0005622=IEA, GO:0016601=IDA, GO:0005737=IDA, GO:0005543=IEA, GO:0007411=TAS, GO:0071526=ISS, GO:0005089=IDA, GO:0007155=ISS, GO:0005856=IEA, GO:0030676=ISS, GO:0019898=IEA} Rac protein signal transduction, actin cytoskeleton reorganization, axon guidance, cell adhesion, neuron remodeling, osteoclast differentiation, podosome assembly, regulation of Rho protein signal transduction, regulation of integrin activation, semaphorin-plexin signaling pathway cytoplasm, cytoskeleton, cytosol, extrinsic to membrane, intracellular Rac guanyl-nucleotide exchange factor activity, Rho guanyl-nucleotide exchange factor activity, cytoskeletal protein binding, phospholipid binding Human FARS2 InterPro UniProtKB {GO:0010467=Reactome:REACT_71, GO:0005737=GO_REF:0000002, GO:0000049=GO_REF:0000002, GO:0000287=GO_REF:0000002, GO:0006432=PMID:10329163, GO:0005759=Reactome:REACT_15462, GO:0004826=PMID:10329163, GO:0043039=GO_REF:0000002, GO:0005524=GO_REF:0000002, GO:0004812=GO_REF:0000002, GO:0008033=PMID:10329163, GO:0006418=Reactome:REACT_15482} Q5JRF7 Phenylalanine--tRNA ligase, mitochondrial protein 20130413 {GO:0010467=TAS, GO:0005737=IEA, GO:0000049=IEA, GO:0000287=IEA, GO:0006432=IDA, GO:0005759=TAS, GO:0004826=IDA, GO:0043039=IEA, GO:0005524=IEA, GO:0004812=IEA, GO:0008033=IDA, GO:0006418=TAS} gene expression, phenylalanyl-tRNA aminoacylation, tRNA aminoacylation, tRNA aminoacylation for protein translation, tRNA processing cytoplasm, mitochondrial matrix ATP binding, aminoacyl-tRNA ligase activity, magnesium ion binding, phenylalanine-tRNA ligase activity, tRNA binding Human InterPro:IPR002319 FARSA HPA UniProtKB {GO:0005515=PMID:21163940, GO:0010467=Reactome:REACT_71, GO:0005737=GO_REF:0000052, GO:0000049=GO_REF:0000002, GO:0006432=GO_REF:0000002, GO:0004826=GO_REF:0000003, GO:0043039=GO_REF:0000002, GO:0005524=GO_REF:0000037, GO:0004812=GO_REF:0000002, GO:0006418=Reactome:REACT_15482, GO:0005829=Reactome:REACT_15328} Q9Y285 Phenylalanine--tRNA ligase alpha subunit protein 20080818 {GO:0005515=IPI, GO:0010467=TAS, GO:0005737=IDA, GO:0000049=IEA, GO:0006432=IEA, GO:0004826=IEA, GO:0043039=IEA, GO:0005524=IEA, GO:0004812=IEA, GO:0006418=TAS, GO:0005829=TAS} gene expression, phenylalanyl-tRNA aminoacylation, tRNA aminoacylation, tRNA aminoacylation for protein translation cytoplasm, cytosol ATP binding, aminoacyl-tRNA ligase activity, phenylalanine-tRNA ligase activity, protein binding, tRNA binding Human FARSB Reactome UniProtKB {GO:0010467=Reactome:REACT_71, GO:0005737=PMID:10049785, GO:0000287=GO_REF:0000002, GO:0006432=GO_REF:0000002, GO:0003723=GO_REF:0000002, GO:0004826=GO_REF:0000003, GO:0006412=PMID:10049785, GO:0005524=GO_REF:0000037, GO:0006418=Reactome:REACT_15482, GO:0005829=Reactome:REACT_15328} Q9NSD9 Phenylalanine--tRNA ligase beta subunit protein 20130213 {GO:0010467=TAS, GO:0005737=TAS, GO:0000287=IEA, GO:0006432=IEA, GO:0003723=IEA, GO:0004826=IEA, GO:0006412=TAS, GO:0005524=IEA, GO:0006418=TAS, GO:0005829=TAS} gene expression, phenylalanyl-tRNA aminoacylation, tRNA aminoacylation for protein translation, translation cytoplasm, cytosol ATP binding, RNA binding, magnesium ion binding, phenylalanine-tRNA ligase activity Human FAS HPA UniProtKB {GO:0005515=PMID:21803845, GO:0019724=GO_REF:0000019, GO:0010467=GO_REF:0000019, GO:0031265=PMID:20935634, GO:0031264=PMID:11101870, GO:0051402=GO_REF:0000019, GO:0048536=GO_REF:0000019, GO:0042802=PMID:21382479, GO:0045619=GO_REF:0000019, GO:0051260=GO_REF:0000019, GO:0010940=PMID:16507998, GO:0032464=GO_REF:0000019, GO:0071285=GO_REF:0000019, GO:0009636=GO_REF:0000019, GO:0051384=GO_REF:0000019, GO:0045121=PMID:21382479, GO:0002377=GO_REF:0000019, GO:0009897=GO_REF:0000019, GO:0004888=GO_REF:0000002, GO:0008625=GO_REF:0000019, GO:0005886=GO_REF:0000052, GO:0006927=GO_REF:0000019, GO:0006925=GO_REF:0000019, GO:0005634=GO_REF:0000052, GO:0006924=GO_REF:0000019, GO:0005829=PMID:7533181, GO:0006955=GO_REF:0000002, GO:0005737=GO_REF:0000052, GO:0045637=GO_REF:0000019, GO:0004872=PMID:7533181, GO:0004871=PMID:9360929, GO:0019900=PMID:7538908, GO:0043066=GO_REF:0000019, GO:0043065=PMID:20935634, GO:0050869=GO_REF:0000019, GO:0006919=Reactome:REACT_1503, GO:0071455=PMID:21382479, GO:0006915=Reactome:REACT_578, GO:0005576=GO_REF:0000039, GO:0042981=PMID:7533181, GO:0006917=PMID:1375228, GO:0097190=Reactome:REACT_1619, GO:0003014=GO_REF:0000019, GO:0007165=PMID:9360929, GO:0006461=PMID:10875918, GO:0016020=GO_REF:0000002, GO:0045060=GO_REF:0000019, GO:0016021=GO_REF:0000037, GO:0071260=PMID:19593445} P25445 Tumor necrosis factor receptor superfamily member 6 protein 20111111 {GO:0005515=IPI, GO:0019724=IEA, GO:0010467=IEA, GO:0031265=IDA, GO:0031264=IDA, GO:0051402=IEA, GO:0048536=IEA, GO:0042802=IPI, GO:0045619=IEA, GO:0051260=IEA, GO:0010940=IMP, GO:0032464=IEA, GO:0071285=IEA, GO:0009636=IEA, GO:0051384=IEA, GO:0045121=IDA, GO:0002377=IEA, GO:0009897=IEA, GO:0004888=IEA, GO:0008625=IEA, GO:0005886=IDA, GO:0006927=IEA, GO:0006925=IEA, GO:0005634=IDA, GO:0006924=IEA, GO:0005829=NAS, GO:0006955=IEA, GO:0005737=IDA, GO:0045637=IEA, GO:0004872=NAS, GO:0004871=TAS, GO:0019900=IPI, GO:0043066=IEA, GO:0043065=IMP, GO:0050869=IEA, GO:0006919=TAS, GO:0071455=IMP, GO:0006915=TAS, GO:0005576=IEA, GO:0042981=NAS, GO:0006917=TAS, GO:0097190=TAS, GO:0003014=IEA, GO:0007165=TAS, GO:0006461=TAS, GO:0016020=IEA, GO:0045060=IEA, GO:0016021=IEA, GO:0071260=IEP} B cell mediated immunity, activation of cysteine-type endopeptidase activity involved in apoptotic process, activation-induced cell death of T cells, apoptotic process, apoptotic signaling pathway, cellular response to hyperoxia, cellular response to lithium ion, cellular response to mechanical stimulus, extrinsic apoptotic signaling pathway via death domain receptors, gene expression, immune response, immunoglobulin production, induction of apoptosis, inflammatory cell apoptotic process, negative regulation of B cell activation, negative regulation of apoptotic process, negative thymic T cell selection, neuron apoptotic process, positive regulation of apoptotic process, positive regulation of necrotic cell death, positive regulation of protein homooligomerization, protein complex assembly, protein homooligomerization, regulation of apoptotic process, regulation of lymphocyte differentiation, regulation of myeloid cell differentiation, renal system process, response to glucocorticoid stimulus, response to toxic substance, signal transduction, spleen development, transformed cell apoptotic process CD95 death-inducing signaling complex, cytoplasm, cytosol, death-inducing signaling complex, external side of plasma membrane, extracellular region, integral to membrane, membrane, membrane raft, nucleus, plasma membrane identical protein binding, kinase binding, protein binding, receptor activity, signal transducer activity, transmembrane signaling receptor activity Human FASLG BHF-UCL UniProtKB {GO:0005515=PMID:21803845, GO:0008625=GO_REF:0000019, GO:0008284=GO_REF:0000019, GO:0048471=GO_REF:0000019, GO:0060554=PMID:11101870, GO:0060555=PMID:11101870, GO:0007267=PMID:7826947, GO:0006925=GO_REF:0000019, GO:0005634=PMID:17557115, GO:0060205=GO_REF:0000039, GO:0005615=PMID:18835034, GO:0006955=GO_REF:0000002, GO:0043525=GO_REF:0000019, GO:0032496=GO_REF:0000019, GO:0043123=PMID:12761501, GO:0043202=GO_REF:0000039, GO:0005164=GO_REF:0000019, GO:0070265=PMID:11101870, GO:0043065=PMID:14749367, GO:0045742=GO_REF:0000019, GO:0006919=PMID:18293083, GO:0005102=PMID:7826947, GO:0006915=Reactome:REACT_578, GO:0005576=Reactome:REACT_2191, GO:0033554=GO_REF:0000019, GO:0000122=PMID:17557115, GO:0070848=GO_REF:0000019, GO:0097190=PMID:11101870, GO:0005125=GO_REF:0000037, GO:0006351=GO_REF:0000037, GO:0007165=PMID:7826947, GO:0030644=GO_REF:0000019, GO:0048388=GO_REF:0000019, GO:0005887=PMID:7826947, GO:0005901=GO_REF:0000019, GO:0016525=PMID:18835034, GO:0046666=GO_REF:0000019, GO:0009897=GO_REF:0000019} P48023 Tumor necrosis factor ligand superfamily member 6 protein 20100331 {GO:0005515=IPI, GO:0008625=IEA, GO:0008284=IEA, GO:0048471=IEA, GO:0060554=IDA, GO:0060555=IDA, GO:0007267=TAS, GO:0006925=IEA, GO:0005634=IDA, GO:0060205=IEA, GO:0005615=IDA, GO:0006955=IEA, GO:0043525=IEA, GO:0032496=IEA, GO:0043123=IEP, GO:0043202=IEA, GO:0005164=IEA, GO:0070265=IDA, GO:0043065=IDA, GO:0045742=IEA, GO:0006919=IMP, GO:0005102=TAS, GO:0006915=TAS, GO:0005576=TAS, GO:0033554=IEA, GO:0000122=IDA, GO:0070848=IEA, GO:0097190=IDA, GO:0005125=IEA, GO:0006351=IEA, GO:0007165=TAS, GO:0030644=IEA, GO:0048388=IEA, GO:0005887=TAS, GO:0005901=IEA, GO:0016525=IDA, GO:0046666=IEA, GO:0009897=IEA} activation of cysteine-type endopeptidase activity involved in apoptotic process, activation of necroptosis by extracellular signals, activation of necroptosis of activated-T cells, apoptotic process, apoptotic signaling pathway, cell-cell signaling, cellular chloride ion homeostasis, cellular response to stress, endosomal lumen acidification, extrinsic apoptotic signaling pathway via death domain receptors, immune response, inflammatory cell apoptotic process, necrotic cell death, negative regulation of angiogenesis, negative regulation of transcription from RNA polymerase II promoter, positive regulation of I-kappaB kinase/NF-kappaB cascade, positive regulation of apoptotic process, positive regulation of cell proliferation, positive regulation of epidermal growth factor receptor signaling pathway, positive regulation of neuron apoptotic process, response to growth factor stimulus, response to lipopolysaccharide, retinal cell programmed cell death, signal transduction, transcription, DNA-dependent caveola, cytoplasmic membrane-bounded vesicle lumen, external side of plasma membrane, extracellular region, extracellular space, integral to plasma membrane, lysosomal lumen, nucleus, perinuclear region of cytoplasm cytokine activity, protein binding, receptor binding, tumor necrosis factor receptor binding Human FASN HPA UniProtKB {GO:0005515=PMID:18022563, GO:0005886=GO_REF:0000052, GO:0015939=Reactome:REACT_11172, GO:0006767=Reactome:REACT_11238, GO:0044281=Reactome:REACT_111217, GO:0035338=Reactome:REACT_1319, GO:0070402=GO_REF:0000019, GO:0042803=GO_REF:0000019, GO:0005829=Reactome:REACT_115784, GO:0005739=GO_REF:0000019, GO:0005737=GO_REF:0000052, GO:0008144=GO_REF:0000019, GO:0019432=Reactome:REACT_1190, GO:0006631=PMID:7835891, GO:0006633=GO_REF:0000019, GO:0004313=GO_REF:0000003, GO:0004312=Reactome:REACT_1497, GO:0044255=Reactome:REACT_22279, GO:0042470=GO_REF:0000039, GO:0005794=GO_REF:0000052, GO:0016295=GO_REF:0000003, GO:0004319=GO_REF:0000003, GO:0016296=GO_REF:0000003, GO:0004315=GO_REF:0000003, GO:0047451=GO_REF:0000003, GO:0004314=GO_REF:0000003, GO:0006084=GO_REF:0000019, GO:0004317=GO_REF:0000002, GO:0004316=GO_REF:0000003, GO:0042587=GO_REF:0000019, GO:0031325=Reactome:REACT_2122, GO:0006112=Reactome:REACT_1505, GO:0006766=Reactome:REACT_11193, GO:0004320=GO_REF:0000003, GO:0008270=GO_REF:0000002} P49327 Fatty acid synthase protein 20101115 {GO:0005515=IPI, GO:0005886=IDA, GO:0015939=TAS, GO:0006767=TAS, GO:0044281=TAS, GO:0035338=TAS, GO:0070402=IEA, GO:0042803=IEA, GO:0005829=TAS, GO:0005739=IEA, GO:0005737=IDA, GO:0008144=IEA, GO:0019432=TAS, GO:0006631=TAS, GO:0006633=IEA, GO:0004313=IEA, GO:0004312=TAS, GO:0044255=TAS, GO:0042470=IEA, GO:0005794=IDA, GO:0016295=IEA, GO:0004319=IEA, GO:0016296=IEA, GO:0004315=IEA, GO:0047451=IEA, GO:0004314=IEA, GO:0006084=IEA, GO:0004317=IEA, GO:0004316=IEA, GO:0042587=IEA, GO:0031325=TAS, GO:0006112=TAS, GO:0006766=TAS, GO:0004320=IEA, GO:0008270=IEA} acetyl-CoA metabolic process, cellular lipid metabolic process, energy reserve metabolic process, fatty acid biosynthetic process, fatty acid metabolic process, long-chain fatty-acyl-CoA biosynthetic process, pantothenate metabolic process, positive regulation of cellular metabolic process, small molecule metabolic process, triglyceride biosynthetic process, vitamin metabolic process, water-soluble vitamin metabolic process Golgi apparatus, cytoplasm, cytosol, glycogen granule, melanosome, mitochondrion, plasma membrane "3-hydroxyoctanoyl-acyl-carrier-protein"" dehydratase activity, 3-hydroxypalmitoyl-""acyl-carrier-protein"" dehydratase activity, 3-oxoacyl-""acyl-carrier-protein"" reductase (NADPH) activity, 3-oxoacyl-""acyl-carrier-protein"" synthase activity, NADPH binding, ""acyl-carrier-protein"" S-acetyltransferase activity, ""acyl-carrier-protein"" S-malonyltransferase activity, drug binding, enoyl-""acyl-carrier-protein"" reductase (NADPH, B-specific) activity, fatty acid synthase activity, myristoyl-""acyl-carrier-protein"" hydrolase activity, oleoyl-""acyl-carrier-protein"" hydrolase activity, palmitoyl-""acyl-carrier-protein"" hydrolase activity, protein binding, protein homodimerization activity, zinc ion binding""" Human FASTK PINC UniProtKB {GO:0005515=PMID:7544399, GO:0005739=GO_REF:0000019, GO:0004672=GO_REF:0000002, GO:0004674=PMID:7544399, GO:0016301=GO_REF:0000038, GO:0043484=PMID:17592127, GO:0006468=PMID:7544399, GO:0033867=GO_REF:0000003, GO:0097190=PMID:7544399, GO:0005524=GO_REF:0000037} Q14296 Fas-activated serine/threonine kinase protein 20030904 {GO:0005515=IPI, GO:0005739=IEA, GO:0004672=IEA, GO:0004674=IDA, GO:0016301=IEA, GO:0043484=IMP, GO:0006468=IDA, GO:0033867=IEA, GO:0097190=TAS, GO:0005524=IEA} apoptotic signaling pathway, protein phosphorylation, regulation of RNA splicing mitochondrion ATP binding, Fas-activated serine/threonine kinase activity, kinase activity, protein binding, protein kinase activity, protein serine/threonine kinase activity Human FASTKD1 UniProtKB UniProtKB {GO:0005739=PMID:20869947, GO:0045333=PMID:20869947, GO:0004672=GO_REF:0000002} Q53R41 FAST kinase domain-containing protein 1 protein 20101208 {GO:0005739=IDA, GO:0045333=ISS, GO:0004672=IEA} cellular respiration mitochondrion protein kinase activity Human UniProtKB:Q14CZ7 FASTKD2 UniProtKB UniProtKB {GO:0005739=PMID:20869947, GO:0045333=PMID:20869947, GO:0004672=GO_REF:0000002} Q9NYY8 FAST kinase domain-containing protein 2 protein 20101208 {GO:0005739=IDA, GO:0045333=ISS, GO:0004672=IEA} cellular respiration mitochondrion protein kinase activity Human UniProtKB:Q14CZ7 FASTKD3 UniProtKB UniProtKB {GO:0005739=PMID:20869947, GO:0045333=PMID:20869947, GO:0004672=GO_REF:0000002} Q14CZ7 FAST kinase domain-containing protein 3 protein 20101208 {GO:0005739=IDA, GO:0045333=IMP, GO:0004672=IEA} cellular respiration mitochondrion protein kinase activity Human FASTKD5 UniProtKB UniProtKB {GO:0005739=PMID:20869947, GO:0045333=PMID:20869947, GO:0004672=GO_REF:0000002} Q7L8L6 FAST kinase domain-containing protein 5 protein 20101208 {GO:0005739=IDA, GO:0045333=ISS, GO:0004672=IEA} cellular respiration mitochondrion protein kinase activity Human UniProtKB:Q14CZ7 FAT1 PINC UniProtKB {GO:0005515=PMID:19131340, GO:0048471=PMID:15922730, GO:0030054=GO_REF:0000019, GO:0005886=PMID:15922730, GO:0005509=GO_REF:0000002, GO:0007267=PMID:8586420, GO:0005634=PMID:15922730, GO:0030175=GO_REF:0000019, GO:0009653=PMID:8586420, GO:0030027=GO_REF:0000019, GO:0016337=GO_REF:0000024, GO:0007163=GO_REF:0000024, GO:0016477=GO_REF:0000024, GO:0005887=PMID:8586420, GO:0005911=PMID:15148305, GO:0007015=GO_REF:0000024, GO:0016021=GO_REF:0000038, GO:0007155=PMID:8586420, GO:0007156=GO_REF:0000002} Q14517 Protocadherin Fat 1 protein 20031119 {GO:0005515=IPI, GO:0048471=IDA, GO:0030054=IEA, GO:0005886=IDA, GO:0005509=IEA, GO:0007267=TAS, GO:0005634=IDA, GO:0030175=IEA, GO:0009653=TAS, GO:0030027=IEA, GO:0016337=ISS, GO:0007163=ISS, GO:0016477=ISS, GO:0005887=TAS, GO:0005911=IDA, GO:0007015=ISS, GO:0016021=IEA, GO:0007155=TAS, GO:0007156=IEA} actin filament organization, anatomical structure morphogenesis, cell adhesion, cell migration, cell-cell adhesion, cell-cell signaling, establishment or maintenance of cell polarity, homophilic cell adhesion cell junction, cell-cell junction, filopodium, integral to membrane, integral to plasma membrane, lamellipodium, nucleus, perinuclear region of cytoplasm, plasma membrane calcium ion binding, protein binding Human FAT2 UniProtKB UniProtKB {GO:0005913=PMID:17900869, GO:0005886=GO_REF:0000039, GO:0005509=GO_REF:0000029, GO:0010631=PMID:17900869, GO:0005634=GO_REF:0000039, GO:0016021=GO_REF:0000037, GO:0007156=GO_REF:0000024} Q9NYQ8 Protocadherin Fat 2 protein 20110211 {GO:0005913=IDA, GO:0005886=IEA, GO:0005509=NAS, GO:0010631=IMP, GO:0005634=IEA, GO:0016021=IEA, GO:0007156=ISS} epithelial cell migration, homophilic cell adhesion cell-cell adherens junction, integral to membrane, nucleus, plasma membrane calcium ion binding Human UniProtKB:O88277 FAT3 UniProtKB UniProtKB {GO:0005886=GO_REF:0000002, GO:0005509=GO_REF:0000002, GO:0007275=GO_REF:0000037, GO:0016021=GO_REF:0000037, GO:0007156=GO_REF:0000002} Q8TDW7 Protocadherin Fat 3 protein 20130413 {GO:0005886=IEA, GO:0005509=IEA, GO:0007275=IEA, GO:0016021=IEA, GO:0007156=IEA} homophilic cell adhesion, multicellular organismal development integral to membrane, plasma membrane calcium ion binding Human UniProtKB-KW:KW-0812 FAT4 IntAct UniProtKB {GO:0005515=PMID:22153077, GO:0005886=GO_REF:0000002, GO:0005509=GO_REF:0000002, GO:0016021=GO_REF:0000037, GO:0007156=GO_REF:0000002} Q6V0I7 Protocadherin Fat 4 protein 20130415 {GO:0005515=IPI, GO:0005886=IEA, GO:0005509=IEA, GO:0016021=IEA, GO:0007156=IEA} homophilic cell adhesion integral to membrane, plasma membrane calcium ion binding, protein binding Human UniProtKB:Q9H2K2 FATE1 LIFEdb UniProtKB {GO:0005783=GO_REF:0000054, GO:0016021=GO_REF:0000037} Q969F0 Fetal and adult testis-expressed transcript protein protein 20100607 {GO:0005783=IDA, GO:0016021=IEA} endoplasmic reticulum, integral to membrane Human FAU Reactome UniProtKB {GO:0010467=Reactome:REACT_71, GO:0003735=PMID:15883184, GO:0016070=Reactome:REACT_21257, GO:0016071=Reactome:REACT_20605, GO:0019083=Reactome:REACT_6152, GO:0006614=Reactome:REACT_115902, GO:0003723=PMID:8395683, GO:0019058=Reactome:REACT_6167, GO:0015935=PMID:15883184, GO:0005575=GO_REF:0000015, GO:0006415=Reactome:REACT_1986, GO:0006412=Reactome:REACT_1014, GO:0006413=Reactome:REACT_2159, GO:0005829=Reactome:REACT_115921, GO:0006414=Reactome:REACT_1477, GO:0008150=GO_REF:0000015, GO:0003674=GO_REF:0000015, GO:0000184=Reactome:REACT_75886, GO:0022627=PMID:8706699, GO:0016032=Reactome:REACT_6145, GO:0005840=GO_REF:0000002, GO:0044267=Reactome:REACT_17015} P62861 40S ribosomal protein S30 protein 20130213 {GO:0010467=TAS, GO:0003735=IDA, GO:0016070=TAS, GO:0016071=TAS, GO:0019083=TAS, GO:0006614=TAS, GO:0003723=TAS, GO:0019058=TAS, GO:0015935=IDA, GO:0005575=ND, GO:0006415=TAS, GO:0006412=TAS, GO:0006413=TAS, GO:0005829=TAS, GO:0006414=TAS, GO:0008150=ND, GO:0003674=ND, GO:0000184=TAS, GO:0022627=IDA, GO:0016032=TAS, GO:0005840=IEA, GO:0044267=TAS} RNA metabolic process, SRP-dependent cotranslational protein targeting to membrane, biological_process, cellular protein metabolic process, gene expression, mRNA metabolic process, nuclear-transcribed mRNA catabolic process, nonsense-mediated decay, translation, translational elongation, translational initiation, translational termination, viral infectious cycle, viral reproduction, viral transcription cellular_component, cytosol, cytosolic small ribosomal subunit, ribosome, small ribosomal subunit RNA binding, molecular_function, structural constituent of ribosome Human FBF1 UniProtKB UniProtKB {GO:0090162=PMID:18838552, GO:0043297=PMID:18838552, GO:0005515=PMID:18838552, GO:0043296=PMID:18838552, GO:0000922=PMID:21399614, GO:0005814=GO_REF:0000039, GO:0045095=PMID:18838552} Q8TES7 Fas-binding factor 1 protein 20110518 {GO:0090162=IMP, GO:0043297=IMP, GO:0005515=IPI, GO:0043296=IDA, GO:0000922=IDA, GO:0005814=IEA, GO:0045095=IDA} apical junction assembly, establishment of epithelial cell polarity apical junction complex, centriole, keratin filament, spindle pole protein binding Human FBL BHF-UCL UniProtKB {GO:0005515=PMID:10837141, GO:0016074=GO_REF:0000019, GO:0015030=PMID:16687569, GO:0031428=PMID:17636026, GO:0001652=GO_REF:0000019, GO:0006364=GO_REF:0000037, GO:0003723=GO_REF:0000037, GO:0008168=GO_REF:0000037, GO:0005730=PMID:16687569, GO:0008033=GO_REF:0000002} P22087 rRNA 2'-O-methyltransferase fibrillarin protein 20091118 {GO:0005515=IPI, GO:0016074=IEA, GO:0015030=IDA, GO:0031428=NAS, GO:0001652=IEA, GO:0006364=IEA, GO:0003723=IEA, GO:0008168=IEA, GO:0005730=IDA, GO:0008033=IEA} rRNA processing, snoRNA metabolic process, tRNA processing Cajal body, box C/D snoRNP complex, granular component, nucleolus RNA binding, methyltransferase activity, protein binding Human FBLIM1 HPA UniProtKB {GO:0001725=PMID:18829455, GO:0016337=PMID:19074766, GO:0030054=GO_REF:0000052, GO:0034329=Reactome:REACT_20676, GO:0031005=PMID:19074766, GO:0008360=GO_REF:0000037, GO:0008270=GO_REF:0000002, GO:0005938=GO_REF:0000039, GO:0005925=GO_REF:0000039, GO:0033623=PMID:19074766, GO:0043231=GO_REF:0000052, GO:0005829=Reactome:REACT_20572} Q8WUP2 Filamin-binding LIM protein 1 protein 20100326 {GO:0001725=IDA, GO:0016337=IMP, GO:0030054=IDA, GO:0034329=TAS, GO:0031005=IDA, GO:0008360=IEA, GO:0008270=IEA, GO:0005938=IEA, GO:0005925=IEA, GO:0033623=IMP, GO:0043231=IDA, GO:0005829=TAS} cell junction assembly, cell-cell adhesion, regulation of cell shape, regulation of integrin activation cell cortex, cell junction, cytosol, focal adhesion, intracellular membrane-bounded organelle, stress fiber filamin binding, zinc ion binding Human FBLN1 Reactome UniProtKB {GO:0016504=GO_REF:0000019, GO:0030198=Reactome:REACT_118779, GO:0007566=GO_REF:0000019, GO:0019048=GO_REF:0000037, GO:0005509=GO_REF:0000002, GO:0005578=PMID:2269669, GO:0005576=Reactome:REACT_150469, GO:0005201=PMID:2269669, GO:0005604=GO_REF:0000019} P23142 Fibulin-1 protein 20130301 {GO:0016504=IEA, GO:0030198=TAS, GO:0007566=IEA, GO:0019048=IEA, GO:0005509=IEA, GO:0005578=TAS, GO:0005576=TAS, GO:0005201=TAS, GO:0005604=IEA} embryo implantation, extracellular matrix organization, virus-host interaction basement membrane, extracellular region, proteinaceous extracellular matrix calcium ion binding, extracellular matrix structural constituent, peptidase activator activity Human FBLN2 BHF-UCL UniProtKB {GO:0031012=PMID:22261194, GO:0030198=Reactome:REACT_118779, GO:0005509=GO_REF:0000002, GO:0010811=GO_REF:0000019, GO:0005578=GO_REF:0000039, GO:0050840=GO_REF:0000019, GO:0005576=Reactome:REACT_150469, GO:0005201=PMID:7806230} P98095 Fibulin-2 protein 20120228 {GO:0031012=ISS, GO:0030198=TAS, GO:0005509=IEA, GO:0010811=IEA, GO:0005578=IEA, GO:0050840=IEA, GO:0005576=TAS, GO:0005201=TAS} extracellular matrix organization, positive regulation of cell-substrate adhesion extracellular matrix, extracellular region, proteinaceous extracellular matrix calcium ion binding, extracellular matrix binding, extracellular matrix structural constituent colocalizes_with Human UniProtKB:F1SPG5 FBLN5 HPA UniProtKB {GO:0005515=PMID:19570982, GO:0005509=GO_REF:0000002, GO:0005578=PMID:10428823, GO:0005576=Reactome:REACT_150335, GO:0071953=GO_REF:0000024, GO:0008022=PMID:15528465, GO:0001558=GO_REF:0000019, GO:0005615=GO_REF:0000019, GO:2000121=GO_REF:0000024, GO:0005737=GO_REF:0000052, GO:0005178=PMID:10428823, GO:0007160=PMID:10428823, GO:0016020=GO_REF:0000002, GO:0030198=Reactome:REACT_118779, GO:0007596=GO_REF:0000002, GO:0034394=GO_REF:0000024, GO:0048251=GO_REF:0000024, GO:0004888=GO_REF:0000002} Q9UBX5 Fibulin-5 protein 20080205 {GO:0005515=IPI, GO:0005509=IEA, GO:0005578=TAS, GO:0005576=TAS, GO:0071953=ISS, GO:0008022=IPI, GO:0001558=IEA, GO:0005615=IEA, GO:2000121=ISS, GO:0005737=IDA, GO:0005178=TAS, GO:0007160=TAS, GO:0016020=IEA, GO:0030198=TAS, GO:0007596=IEA, GO:0034394=ISS, GO:0048251=ISS, GO:0004888=IEA} blood coagulation, cell-matrix adhesion, elastic fiber assembly, extracellular matrix organization, protein localization to cell surface, regulation of cell growth, regulation of removal of superoxide radicals cytoplasm, elastic fiber, extracellular region, extracellular space, membrane, proteinaceous extracellular matrix calcium ion binding, integrin binding, protein C-terminus binding, protein binding, transmembrane signaling receptor activity Human FBN1 BHF-UCL UniProtKB {GO:0005515=PMID:19570982, GO:0035583=GO_REF:0000024, GO:0035582=GO_REF:0000024, GO:0005509=PMID:7691719, GO:0005578=PMID:3536967, GO:0001527=PMID:1860873, GO:0005576=Reactome:REACT_150459, GO:0005615=PMID:3536967, GO:0005604=PMID:3536967, GO:0031012=GO_REF:0000019, GO:0007507=PMID:15781745, GO:0001501=PMID:8188302, GO:0030198=Reactome:REACT_118779, GO:0005201=PMID:3536967} P35555 Fibrillin-1 protein 20101031 {GO:0005515=IPI, GO:0035583=ISS, GO:0035582=ISS, GO:0005509=IDA, GO:0005578=IDA, GO:0001527=IDA, GO:0005576=TAS, GO:0005615=IDA, GO:0005604=IDA, GO:0031012=IEA, GO:0007507=IMP, GO:0001501=IMP, GO:0030198=TAS, GO:0005201=IDA} extracellular matrix organization, heart development, sequestering of BMP in extracellular matrix, sequestering of TGFbeta in extracellular matrix, skeletal system development basement membrane, extracellular matrix, extracellular region, extracellular space, microfibril, proteinaceous extracellular matrix calcium ion binding, extracellular matrix structural constituent, protein binding Human UniProtKB:Q61554 FBN2 BHF-UCL UniProtKB {GO:0045669=GO_REF:0000024, GO:0035583=GO_REF:0000024, GO:0060346=GO_REF:0000024, GO:0030501=GO_REF:0000024, GO:0030198=Reactome:REACT_118779, GO:0005509=GO_REF:0000002, GO:0005578=PMID:8120105, GO:0001527=PMID:20855508, GO:0005576=Reactome:REACT_150459, GO:0030326=GO_REF:0000019, GO:0009653=PMID:7493032, GO:0005201=GO_REF:0000002} P35556 Fibrillin-2 protein 20101031 {GO:0045669=ISS, GO:0035583=ISS, GO:0060346=ISS, GO:0030501=ISS, GO:0030198=TAS, GO:0005509=IEA, GO:0005578=TAS, GO:0001527=TAS, GO:0005576=TAS, GO:0030326=IEA, GO:0009653=TAS, GO:0005201=IEA} anatomical structure morphogenesis, bone trabecula formation, embryonic limb morphogenesis, extracellular matrix organization, positive regulation of bone mineralization, positive regulation of osteoblast differentiation, sequestering of TGFbeta in extracellular matrix extracellular region, microfibril, proteinaceous extracellular matrix calcium ion binding, extracellular matrix structural constituent Human FBN3 UniProtKB UniProtKB {GO:0005509=GO_REF:0000002, GO:0005578=GO_REF:0000039, GO:0005201=GO_REF:0000002} Q75N90 Fibrillin-3 protein 20130413 {GO:0005509=IEA, GO:0005578=IEA, GO:0005201=IEA} proteinaceous extracellular matrix calcium ion binding, extracellular matrix structural constituent Human UniProtKB-SubCell:SL-0111 FBP1 InterPro UniProtKB {GO:0005515=PMID:16275660, GO:0030308=PMID:19881551, GO:0016208=PMID:18650089, GO:0005975=GO_REF:0000002, GO:0071286=PMID:10222032, GO:0006094=Reactome:REACT_1520, GO:0044281=Reactome:REACT_111217, GO:0035690=PMID:18650089, GO:0046872=PMID:8387495, GO:0005829=Reactome:REACT_379, GO:0006111=PMID:7558035, GO:0046580=PMID:19881551, GO:0005737=PMID:20096900, GO:0051289=PMID:18650089, GO:0016311=PMID:18650089, GO:0006006=Reactome:REACT_723, GO:0045820=PMID:19881551, GO:0048029=GO_REF:0000024, GO:0006002=PMID:16442285, GO:0006000=PMID:7558035, GO:0042132=GO_REF:0000002} Q5VZC3 Fructose-1,6-bisphosphatase 1 protein 20130413 {GO:0005515=IPI, GO:0030308=IDA, GO:0016208=IDA, GO:0005975=IEA, GO:0071286=IDA, GO:0006094=TAS, GO:0044281=TAS, GO:0035690=IDA, GO:0046872=IMP, GO:0005829=TAS, GO:0006111=IMP, GO:0046580=IDA, GO:0005737=IDA, GO:0051289=IDA, GO:0016311=IDA, GO:0006006=TAS, GO:0045820=IDA, GO:0048029=ISS, GO:0006002=IDA, GO:0006000=TAS, GO:0042132=IEA} carbohydrate metabolic process, cellular response to drug, cellular response to magnesium ion, dephosphorylation, fructose 6-phosphate metabolic process, fructose metabolic process, gluconeogenesis, glucose metabolic process, negative regulation of Ras protein signal transduction, negative regulation of cell growth, negative regulation of glycolysis, protein homotetramerization, regulation of gluconeogenesis, small molecule metabolic process cytoplasm, cytosol AMP binding, fructose 1,6-bisphosphate 1-phosphatase activity, metal ion binding, monosaccharide binding, protein binding Human InterPro:IPR000146 FBP2 Reactome UniProtKB {GO:0005975=Reactome:REACT_474, GO:0004331=PMID:9678974, GO:0006094=Reactome:REACT_1520, GO:0006006=Reactome:REACT_723, GO:0044281=Reactome:REACT_111217, GO:0046872=GO_REF:0000037, GO:0005829=Reactome:REACT_379, GO:0006000=PMID:9678974, GO:0042132=GO_REF:0000003} O00757 Fructose-1,6-bisphosphatase isozyme 2 protein 20130213 {GO:0005975=TAS, GO:0004331=TAS, GO:0006094=TAS, GO:0006006=TAS, GO:0044281=TAS, GO:0046872=IEA, GO:0005829=TAS, GO:0006000=TAS, GO:0042132=IEA} carbohydrate metabolic process, fructose metabolic process, gluconeogenesis, glucose metabolic process, small molecule metabolic process cytosol fructose 1,6-bisphosphate 1-phosphatase activity, fructose-2,6-bisphosphate 2-phosphatase activity, metal ion binding Human FBRS ENSEMBL UniProtKB {GO:0048146=GO_REF:0000019, GO:0008083=GO_REF:0000019, GO:0005615=GO_REF:0000019} J3KNZ9 Probable fibrosin-1 protein 20130413 {GO:0048146=IEA, GO:0008083=IEA, GO:0005615=IEA} positive regulation of fibroblast proliferation extracellular space growth factor activity Human Ensembl:ENSMUSP00000043682 FBRSL1 null null {} null null null null {} null null null FBXL12 IntAct UniProtKB {GO:0005515=PMID:21163940, GO:0006511=GO_REF:0000019, GO:0005737=GO_REF:0000019, GO:0000151=GO_REF:0000019} Q9NXK8 F-box/LRR-repeat protein 12 protein 20130415 {GO:0005515=IPI, GO:0006511=IEA, GO:0005737=IEA, GO:0000151=IEA} ubiquitin-dependent protein catabolic process cytoplasm, ubiquitin ligase complex protein binding Human UniProtKB:Q9H0A6 FBXL13 null null {} null null null null {} null null null FBXL14 UniProtKB UniProtKB {GO:0005515=PMID:19955572, GO:0004842=PMID:19955572, GO:0005737=PMID:19955572, GO:0042787=PMID:19955572} Q8N1E6 F-box/LRR-repeat protein 14 protein 20110719 {GO:0005515=IPI, GO:0004842=IDA, GO:0005737=IDA, GO:0042787=IDA} protein ubiquitination involved in ubiquitin-dependent protein catabolic process cytoplasm protein binding, ubiquitin-protein ligase activity Human FBXL15 UniProtKB UniProtKB {GO:0005515=PMID:21572392, GO:0030513=PMID:21572392, GO:0005737=PMID:21572392, GO:0004842=PMID:21572392, GO:0016567=PMID:21572392, GO:0000086=PMID:21572392, GO:0030282=GO_REF:0000024, GO:0009953=GO_REF:0000024, GO:0031146=PMID:21572392, GO:0019005=PMID:21572392} Q9H469 F-box/LRR-repeat protein 15 protein 20110517 {GO:0005515=IPI, GO:0030513=IMP, GO:0005737=IDA, GO:0004842=IDA, GO:0016567=IDA, GO:0000086=IMP, GO:0030282=ISS, GO:0009953=ISS, GO:0031146=IDA, GO:0019005=IDA} G2/M transition of mitotic cell cycle, SCF-dependent proteasomal ubiquitin-dependent protein catabolic process, bone mineralization, dorsal/ventral pattern formation, positive regulation of BMP signaling pathway, protein ubiquitination SCF ubiquitin ligase complex, cytoplasm protein binding, ubiquitin-protein ligase activity Human UniProtKB:D4ABB4 FBXL16 null null {} null null null null {} null null null FBXL17 null null {} null null null null {} null null null FBXL18 null null {} null null null null {} null null null FBXL19 InterPro UniProtKB {GO:0008270=GO_REF:0000002, GO:0003677=GO_REF:0000002} Q6PCT2 F-box/LRR-repeat protein 19 protein 20130413 {GO:0008270=IEA, GO:0003677=IEA} DNA binding, zinc ion binding Human InterPro:IPR001965|InterPro:IPR002857 FBXL2 PINC UniProtKB {GO:0005515=PMID:15893726, GO:0005516=GO_REF:0000037, GO:0006511=GO_REF:0000019, GO:0005737=PMID:10508920, GO:0004842=GO_REF:0000019, GO:0006513=GO_REF:0000019, GO:0016020=PMID:15893726, GO:0019048=GO_REF:0000037, GO:0006508=PMID:10531035, GO:0006464=PMID:10531035} Q9UKC9 F-box/LRR-repeat protein 2 protein 20050308 {GO:0005515=IPI, GO:0005516=IEA, GO:0006511=IEA, GO:0005737=TAS, GO:0004842=IEA, GO:0006513=IEA, GO:0016020=IDA, GO:0019048=IEA, GO:0006508=TAS, GO:0006464=TAS} cellular protein modification process, protein monoubiquitination, proteolysis, ubiquitin-dependent protein catabolic process, virus-host interaction cytoplasm, membrane calmodulin binding, protein binding, ubiquitin-protein ligase activity Human FBXL20 UniProtKB UniProtKB {GO:0005737=GO_REF:0000039} Q96IG2 F-box/LRR-repeat protein 20 protein 20130413 {GO:0005737=IEA} cytoplasm Human UniProtKB-SubCell:SL-0086 FBXL21 UniProtKB UniProtKB {GO:0004842=PMID:10531035, GO:0016567=GO_REF:0000024, GO:0000151=PMID:10531035, GO:0005634=GO_REF:0000024, GO:0048511=GO_REF:0000037, GO:0043153=GO_REF:0000024, GO:0019005=GO_REF:0000024, GO:0005829=GO_REF:0000024} Q9UKT6 F-box/LRR-repeat protein 21 protein 20130315 {GO:0004842=NAS, GO:0016567=ISS, GO:0000151=NAS, GO:0005634=ISS, GO:0048511=IEA, GO:0043153=ISS, GO:0019005=ISS, GO:0005829=ISS} entrainment of circadian clock by photoperiod, protein ubiquitination, rhythmic process SCF ubiquitin ligase complex, cytosol, nucleus, ubiquitin ligase complex ubiquitin-protein ligase activity Human UniProtKB:Q8BFZ4 FBXL22 UniPathway UniProtKB {GO:0030018=GO_REF:0000039, GO:0016567=GO_REF:0000041} Q6P050 F-box and leucine-rich protein 22 protein 20130413 {GO:0030018=IEA, GO:0016567=IEA} protein ubiquitination Z disc Human UniPathway:UPA00143 FBXL3 UniProtKB UniProtKB {GO:0005515=PMID:17463251, GO:0004842=PMID:17463251, GO:0016567=GO_REF:0000024, GO:0042752=PMID:17463251, GO:0000151=PMID:10531035, GO:0005634=GO_REF:0000024, GO:0048511=GO_REF:0000037, GO:0031146=PMID:17463251, GO:0043153=GO_REF:0000024, GO:0019005=PMID:17463251, GO:0005829=GO_REF:0000024} Q9UKT7 F-box/LRR-repeat protein 3 protein 20130315 {GO:0005515=IPI, GO:0004842=IDA, GO:0016567=ISS, GO:0042752=IMP, GO:0000151=NAS, GO:0005634=ISS, GO:0048511=IEA, GO:0031146=IDA, GO:0043153=ISS, GO:0019005=IDA, GO:0005829=ISS} SCF-dependent proteasomal ubiquitin-dependent protein catabolic process, entrainment of circadian clock by photoperiod, protein ubiquitination, regulation of circadian rhythm, rhythmic process SCF ubiquitin ligase complex, cytosol, nucleus, ubiquitin ligase complex protein binding, ubiquitin-protein ligase activity Human UniProtKB:Q8C4V4 FBXL4 HPA UniProtKB {GO:0006511=PMID:10531035, GO:0005737=GO_REF:0000039, GO:0005730=GO_REF:0000052, GO:0000151=PMID:10531035, GO:0005634=GO_REF:0000052} Q9UKA2 F-box/LRR-repeat protein 4 protein 20101115 {GO:0006511=TAS, GO:0005737=IEA, GO:0005730=IDA, GO:0000151=TAS, GO:0005634=IDA} ubiquitin-dependent protein catabolic process cytoplasm, nucleolus, nucleus, ubiquitin ligase complex NOT Human FBXL5 UniProtKB UniProtKB {GO:0005515=PMID:19762597, GO:0048471=PMID:17532294, GO:0004842=PMID:10531035, GO:0016567=PMID:19762597, GO:0005506=PMID:19762596, GO:0000151=PMID:10531035, GO:0031146=PMID:19762596, GO:0055072=PMID:19762596, GO:0019005=PMID:19762597} Q9UKA1 F-box/LRR-repeat protein 5 protein 20091030 {GO:0005515=IPI, GO:0048471=IDA, GO:0004842=NAS, GO:0016567=IDA, GO:0005506=IDA, GO:0000151=NAS, GO:0031146=IDA, GO:0055072=IMP, GO:0019005=IDA} SCF-dependent proteasomal ubiquitin-dependent protein catabolic process, iron ion homeostasis, protein ubiquitination SCF ubiquitin ligase complex, perinuclear region of cytoplasm, ubiquitin ligase complex iron ion binding, protein binding, ubiquitin-protein ligase activity Human UniProtKB:P48200 FBXL6 GOC UniProtKB {GO:0004842=PMID:10531035, GO:0016567=PMID:10531035, GO:0006508=PMID:10531035} Q8N531 F-box/LRR-repeat protein 6 protein 20130413 {GO:0004842=TAS, GO:0016567=TAS, GO:0006508=TAS} protein ubiquitination, proteolysis ubiquitin-protein ligase activity Human FBXL7 UniProtKB UniProtKB {GO:0006511=PMID:10531035, GO:0004842=PMID:10531035, GO:0005737=GO_REF:0000037, GO:0007067=GO_REF:0000024, GO:0005813=GO_REF:0000024, GO:0016567=GO_REF:0000024, GO:0008283=GO_REF:0000024, GO:0000086=GO_REF:0000024, GO:0000151=PMID:10531035, GO:0031146=GO_REF:0000024, GO:0019005=GO_REF:0000024, GO:0051301=GO_REF:0000037} Q9UJT9 F-box/LRR-repeat protein 7 protein 20120430 {GO:0006511=NAS, GO:0004842=NAS, GO:0005737=IEA, GO:0007067=ISS, GO:0005813=ISS, GO:0016567=ISS, GO:0008283=ISS, GO:0000086=ISS, GO:0000151=NAS, GO:0031146=ISS, GO:0019005=ISS, GO:0051301=IEA} G2/M transition of mitotic cell cycle, SCF-dependent proteasomal ubiquitin-dependent protein catabolic process, cell division, cell proliferation, mitosis, protein ubiquitination, ubiquitin-dependent protein catabolic process SCF ubiquitin ligase complex, centrosome, cytoplasm, ubiquitin ligase complex ubiquitin-protein ligase activity Human UniProtKB:Q5BJ29 FBXL8 IntAct UniProtKB {GO:0005515=PMID:19159283} Q96CD0 F-box/LRR-repeat protein 8 protein 20130415 {GO:0005515=IPI} protein binding Human UniProtKB:P63208 FBXO10 UniProtKB UniProtKB {GO:0004842=PMID:10531037, GO:0016567=PMID:10531035, GO:0000151=PMID:10531035} Q9UK96 F-box only protein 10 protein 20010817 {GO:0004842=NAS, GO:0016567=NAS, GO:0000151=NAS} protein ubiquitination ubiquitin ligase complex ubiquitin-protein ligase activity Human FBXO11 HPA UniProtKB {GO:0006511=PMID:10531037, GO:0005737=GO_REF:0000052, GO:0004842=PMID:10531035, GO:0016567=PMID:10531035, GO:0007605=GO_REF:0000019, GO:0005730=GO_REF:0000052, GO:0016274=PMID:16487488, GO:0000151=PMID:10531037, GO:0005634=GO_REF:0000052, GO:0008270=GO_REF:0000002, GO:0035246=PMID:16487488, GO:0006464=PMID:16487488} Q86XK2 F-box only protein 11 protein 20101115 {GO:0006511=NAS, GO:0005737=IDA, GO:0004842=NAS, GO:0016567=NAS, GO:0007605=IEA, GO:0005730=IDA, GO:0016274=IDA, GO:0000151=NAS, GO:0005634=IDA, GO:0008270=IEA, GO:0035246=IDA, GO:0006464=IDA} cellular protein modification process, peptidyl-arginine N-methylation, protein ubiquitination, sensory perception of sound, ubiquitin-dependent protein catabolic process cytoplasm, nucleolus, nucleus, ubiquitin ligase complex protein-arginine N-methyltransferase activity, ubiquitin-protein ligase activity, zinc ion binding Human FBXO15 ENSEMBL UniProtKB {GO:0019005=GO_REF:0000019} Q8NCQ5 F-box only protein 15 protein 20130413 {GO:0019005=IEA} SCF ubiquitin ligase complex Human Ensembl:ENSMUSP00000045925 FBXO16 null null {} null null null null {} null null null FBXO17 UniProtKB UniProtKB {GO:0005515=PMID:18203720, GO:0030163=GO_REF:0000002, GO:0001948=PMID:18203720, GO:0019005=PMID:18203720} Q96EF6 F-box only protein 17 protein 20100625 {GO:0005515=IPI, GO:0030163=IEA, GO:0001948=IDA, GO:0019005=IDA} protein catabolic process SCF ubiquitin ligase complex glycoprotein binding, protein binding Human FBXO18 HPA UniProtKB {GO:0004003=GO_REF:0000002, GO:0005634=GO_REF:0000052, GO:0005524=GO_REF:0000037, GO:0003677=GO_REF:0000037} Q8NFZ0 F-box only protein 18 protein 20080818 {GO:0004003=IEA, GO:0005634=IDA, GO:0005524=IEA, GO:0003677=IEA} nucleus ATP binding, ATP-dependent DNA helicase activity, DNA binding Human FBXO2 PINC UniProtKB {GO:0004842=PMID:10531035, GO:0016567=GO_REF:0000024, GO:0005783=GO_REF:0000037, GO:0030433=GO_REF:0000019, GO:0031146=GO_REF:0000024, GO:0005829=GO_REF:0000024, GO:0001540=GO_REF:0000019, GO:0001948=GO_REF:0000019, GO:0043197=GO_REF:0000019, GO:0031090=GO_REF:0000039, GO:0006508=PMID:10531035, GO:0030246=GO_REF:0000019, GO:0006516=GO_REF:0000024, GO:0031396=GO_REF:0000019, GO:0006464=PMID:10531035, GO:0019005=GO_REF:0000024} Q9UK22 F-box only protein 2 protein 20030904 {GO:0004842=TAS, GO:0016567=ISS, GO:0005783=IEA, GO:0030433=IEA, GO:0031146=ISS, GO:0005829=ISS, GO:0001540=IEA, GO:0001948=IEA, GO:0043197=IEA, GO:0031090=IEA, GO:0006508=TAS, GO:0030246=IEA, GO:0006516=ISS, GO:0031396=IEA, GO:0006464=TAS, GO:0019005=ISS} ER-associated protein catabolic process, SCF-dependent proteasomal ubiquitin-dependent protein catabolic process, cellular protein modification process, glycoprotein catabolic process, protein ubiquitination, proteolysis, regulation of protein ubiquitination SCF ubiquitin ligase complex, cytosol, dendritic spine, endoplasmic reticulum, organelle membrane beta-amyloid binding, carbohydrate binding, glycoprotein binding, ubiquitin-protein ligase activity Human FBXO21 GOC UniProtKB {GO:0006511=PMID:10531035, GO:0004842=PMID:10531035, GO:0016567=PMID:10531035, GO:0000151=PMID:10531035, GO:0003677=GO_REF:0000002} O94952 F-box only protein 21 protein 20130413 {GO:0006511=NAS, GO:0004842=NAS, GO:0016567=NAS, GO:0000151=NAS, GO:0003677=IEA} protein ubiquitination, ubiquitin-dependent protein catabolic process ubiquitin ligase complex DNA binding, ubiquitin-protein ligase activity Human FBXO22 PINC UniProtKB {GO:0000209=GO_REF:0000019, GO:0006511=PMID:10531035, GO:0004842=PMID:10531037, GO:0030018=GO_REF:0000039, GO:2000060=GO_REF:0000019, GO:0005737=GO_REF:0000019, GO:0032436=GO_REF:0000019, GO:0010830=GO_REF:0000019, GO:0005634=GO_REF:0000019, GO:0006464=PMID:10531035, GO:0009267=GO_REF:0000019, GO:0006913=GO_REF:0000019} Q8NEZ5 F-box only protein 22 protein 20061107 {GO:0000209=IEA, GO:0006511=TAS, GO:0004842=TAS, GO:0030018=IEA, GO:2000060=IEA, GO:0005737=IEA, GO:0032436=IEA, GO:0010830=IEA, GO:0005634=IEA, GO:0006464=TAS, GO:0009267=IEA, GO:0006913=IEA} cellular protein modification process, cellular response to starvation, nucleocytoplasmic transport, positive regulation of proteasomal ubiquitin-dependent protein catabolic process, positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process, protein polyubiquitination, regulation of myotube differentiation, ubiquitin-dependent protein catabolic process Z disc, cytoplasm, nucleus ubiquitin-protein ligase activity Human FBXO24 UniProtKB UniProtKB {GO:0004842=PMID:10531035, GO:0016567=PMID:10531035, GO:0000151=PMID:10531035} O75426 F-box only protein 24 protein 20010814 {GO:0004842=NAS, GO:0016567=NAS, GO:0000151=NAS} protein ubiquitination ubiquitin ligase complex ubiquitin-protein ligase activity Human FBXO25 UniProtKB UniProtKB {GO:0004842=PMID:10531035, GO:0016567=GO_REF:0000024, GO:0000151=PMID:10531035, GO:0003779=GO_REF:0000037, GO:0005634=GO_REF:0000024, GO:0019005=GO_REF:0000024} Q8TCJ0 F-box only protein 25 protein 20100622 {GO:0004842=NAS, GO:0016567=ISS, GO:0000151=NAS, GO:0003779=IEA, GO:0005634=ISS, GO:0019005=ISS} protein ubiquitination SCF ubiquitin ligase complex, nucleus, ubiquitin ligase complex actin binding, ubiquitin-protein ligase activity Human UniProtKB:Q9D2Y6 FBXO27 UniProtKB UniProtKB {GO:0005515=PMID:18203720, GO:0030163=GO_REF:0000002, GO:0001948=PMID:18203720, GO:0019005=PMID:18203720} Q8NI29 F-box only protein 27 protein 20100625 {GO:0005515=IPI, GO:0030163=IEA, GO:0001948=IDA, GO:0019005=IDA} protein catabolic process SCF ubiquitin ligase complex glycoprotein binding, protein binding Human FBXO28 null null {} null null null null {} null null null FBXO3 GOC UniProtKB {GO:0005515=PMID:22190034, GO:0004842=PMID:10531035, GO:0016567=PMID:10531035, GO:0006508=PMID:10531035, GO:0005634=GO_REF:0000039} Q9UK99 F-box only protein 3 protein 20130413 {GO:0005515=IPI, GO:0004842=TAS, GO:0016567=TAS, GO:0006508=TAS, GO:0005634=IEA} protein ubiquitination, proteolysis nucleus protein binding, ubiquitin-protein ligase activity Human FBXO30 InterPro UniProtKB {GO:0004842=GO_REF:0000002, GO:0008270=GO_REF:0000002} Q8TB52 F-box only protein 30 protein 20130413 {GO:0004842=IEA, GO:0008270=IEA} ubiquitin-protein ligase activity, zinc ion binding Human InterPro:IPR001293|InterPro:IPR013323 FBXO31 UniProtKB UniProtKB {GO:0008054=PMID:19412162, GO:0016567=GO_REF:0000041, GO:0030332=PMID:19412162, GO:0031571=PMID:19412162, GO:0031146=PMID:19412162, GO:0006974=PMID:19412162, GO:0019005=PMID:19412162} Q5XUX0 F-box only protein 31 protein 20090511 {GO:0008054=IMP, GO:0016567=IEA, GO:0030332=IPI, GO:0031571=IMP, GO:0031146=IDA, GO:0006974=IDA, GO:0019005=IDA} SCF-dependent proteasomal ubiquitin-dependent protein catabolic process, cyclin catabolic process, mitotic G1 DNA damage checkpoint, protein ubiquitination, response to DNA damage stimulus SCF ubiquitin ligase complex cyclin binding Human FBXO32 UniPathway UniProtKB {GO:0005737=GO_REF:0000039, GO:0016567=GO_REF:0000041, GO:0005634=GO_REF:0000039} Q969P5 F-box only protein 32 protein 20130413 {GO:0005737=IEA, GO:0016567=IEA, GO:0005634=IEA} protein ubiquitination cytoplasm, nucleus Human UniPathway:UPA00143 FBXO33 UniPathway UniProtKB {GO:0016567=GO_REF:0000041} Q7Z6M2 F-box only protein 33 protein 20130413 {GO:0016567=IEA} protein ubiquitination Human UniPathway:UPA00143 FBXO34 null null {} null null null null {} null null null FBXO38 UniProtKB UniProtKB {GO:0005737=GO_REF:0000039, GO:0005634=GO_REF:0000039} Q6PIJ6 F-box only protein 38 protein 20130413 {GO:0005737=IEA, GO:0005634=IEA} cytoplasm, nucleus Human UniProtKB-SubCell:SL-0086 FBXO4 IntAct UniProtKB {GO:0000209=PMID:20181953, GO:0005515=PMID:21242966, GO:0004842=PMID:10531035, GO:0005737=GO_REF:0000039, GO:0016567=PMID:10531035, GO:0000151=PMID:10531035, GO:0031146=PMID:20159592, GO:0019005=PMID:20181953, GO:0042803=PMID:20181953} Q9UKT5 F-box only protein 4 protein 20130415 {GO:0000209=IDA, GO:0005515=IPI, GO:0004842=IDA, GO:0005737=IEA, GO:0016567=IDA, GO:0000151=IDA, GO:0031146=IDA, GO:0019005=IDA, GO:0042803=IPI} SCF-dependent proteasomal ubiquitin-dependent protein catabolic process, protein polyubiquitination, protein ubiquitination SCF ubiquitin ligase complex, cytoplasm, ubiquitin ligase complex protein binding, protein homodimerization activity, ubiquitin-protein ligase activity Human UniProtKB:P62260 FBXO40 HPA UniProtKB {GO:0042692=PMID:17928169, GO:0003674=GO_REF:0000015, GO:0005813=GO_REF:0000052, GO:0005737=GO_REF:0000052, GO:0004842=GO_REF:0000002, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0008270=GO_REF:0000002} Q9UH90 F-box only protein 40 protein 20101115 {GO:0042692=ISS, GO:0003674=ND, GO:0005813=IDA, GO:0005737=IDA, GO:0004842=IEA, GO:0005730=IDA, GO:0005634=IDA, GO:0008270=IEA} muscle cell differentiation centrosome, cytoplasm, nucleolus, nucleus molecular_function, ubiquitin-protein ligase activity, zinc ion binding Human FBXO41 null null {} null null null null {} null null null FBXO42 null null {} null null null null {} null null null FBXO44 UniProtKB UniProtKB {GO:0005515=PMID:18203720, GO:0030163=GO_REF:0000002, GO:0019005=PMID:18203720} Q9H4M3 F-box only protein 44 protein 20100614 {GO:0005515=IPI, GO:0030163=IEA, GO:0019005=IDA} protein catabolic process SCF ubiquitin ligase complex protein binding Human UniProtKB:Q13616 FBXO45 UniProtKB UniProtKB {GO:0005515=PMID:19581926, GO:0042734=GO_REF:0000039, GO:0030054=GO_REF:0000037, GO:0016567=GO_REF:0000024, GO:0042787=PMID:19581926, GO:0005886=GO_REF:0000037, GO:0045211=GO_REF:0000039, GO:0014069=GO_REF:0000019, GO:0043161=GO_REF:0000024, GO:0006974=PMID:19581926, GO:0007399=GO_REF:0000037} P0C2W1 F-box/SPRY domain-containing protein 1 protein 20100629 {GO:0005515=IPI, GO:0042734=IEA, GO:0030054=IEA, GO:0016567=ISS, GO:0042787=IDA, GO:0005886=IEA, GO:0045211=IEA, GO:0014069=IEA, GO:0043161=ISS, GO:0006974=IDA, GO:0007399=IEA} nervous system development, proteasomal ubiquitin-dependent protein catabolic process, protein ubiquitination, protein ubiquitination involved in ubiquitin-dependent protein catabolic process, response to DNA damage stimulus cell junction, plasma membrane, postsynaptic density, postsynaptic membrane, presynaptic membrane protein binding Human UniProtKB:Q8K3B1 FBXO46 IntAct UniProtKB {GO:0005515=PMID:22632967} Q6PJ61 F-box only protein 46 protein 20130415 {GO:0005515=IPI} protein binding Human UniProtKB:P63208 FBXO5 HPA UniProtKB {GO:0005515=PMID:18662541, GO:0005634=GO_REF:0000052, GO:0001556=GO_REF:0000019, GO:0031145=Reactome:REACT_6828, GO:0046872=GO_REF:0000037, GO:0005829=Reactome:REACT_6878, GO:0016050=GO_REF:0000019, GO:0007057=GO_REF:0000019, GO:0005737=PMID:11988738, GO:0000082=Reactome:REACT_1783, GO:0000083=Reactome:REACT_683, GO:0000089=GO_REF:0000019, GO:0000087=Reactome:REACT_910, GO:0007091=Reactome:REACT_1016, GO:0019901=PMID:15148369, GO:0060565=PMID:15148369, GO:0005730=GO_REF:0000052, GO:0005819=PMID:15469984, GO:0051437=Reactome:REACT_6821, GO:0051436=PMID:16921029, GO:0051439=Reactome:REACT_6837, GO:0040020=GO_REF:0000019, GO:0007346=GO_REF:0000024, GO:0046785=GO_REF:0000019, GO:0005654=Reactome:REACT_22145, GO:0000278=Reactome:REACT_152, GO:0051301=GO_REF:0000037} Q9UKT4 F-box only protein 5 protein 20111111 {GO:0005515=IPI, GO:0005634=IDA, GO:0001556=IEA, GO:0031145=TAS, GO:0046872=IEA, GO:0005829=TAS, GO:0016050=IEA, GO:0007057=IEA, GO:0005737=IDA, GO:0000082=TAS, GO:0000083=TAS, GO:0000089=IEA, GO:0000087=TAS, GO:0007091=TAS, GO:0019901=IPI, GO:0060565=IDA, GO:0005730=IDA, GO:0005819=IDA, GO:0051437=TAS, GO:0051436=IDA, GO:0051439=TAS, GO:0040020=IEA, GO:0007346=ISS, GO:0046785=IEA, GO:0005654=TAS, GO:0000278=TAS, GO:0051301=IEA} G1/S transition of mitotic cell cycle, M phase of mitotic cell cycle, anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process, cell division, inhibition of mitotic anaphase-promoting complex activity, metaphase/anaphase transition of mitotic cell cycle, microtubule polymerization, mitotic cell cycle, mitotic metaphase, negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle, oocyte maturation, positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle, regulation of meiosis, regulation of mitotic cell cycle, regulation of transcription involved in G1/S phase of mitotic cell cycle, regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle, spindle assembly involved in female meiosis I, vesicle organization cytoplasm, cytosol, nucleolus, nucleoplasm, nucleus, spindle metal ion binding, protein binding, protein kinase binding NOT Human FBXO6 PINC UniProtKB {GO:0006986=GO_REF:0000037, GO:0005515=PMID:19716789, GO:0004842=GO_REF:0000019, GO:0031146=PMID:19716789, GO:0030433=GO_REF:0000024, GO:0030163=GO_REF:0000002, GO:0005737=PMID:19716789, GO:0006281=PMID:19716789, GO:0001948=GO_REF:0000024, GO:0006508=PMID:10531035, GO:0006516=GO_REF:0000019, GO:0030246=GO_REF:0000019, GO:0000077=PMID:19716789, GO:0019005=PMID:19716789} Q9NRD1 F-box only protein 6 protein 20050308 {GO:0006986=IEA, GO:0005515=IPI, GO:0004842=IEA, GO:0031146=IDA, GO:0030433=ISS, GO:0030163=IEA, GO:0005737=IDA, GO:0006281=TAS, GO:0001948=ISS, GO:0006508=TAS, GO:0006516=IEA, GO:0030246=IEA, GO:0000077=TAS, GO:0019005=IDA} DNA damage checkpoint, DNA repair, ER-associated protein catabolic process, SCF-dependent proteasomal ubiquitin-dependent protein catabolic process, glycoprotein catabolic process, protein catabolic process, proteolysis, response to unfolded protein SCF ubiquitin ligase complex, cytoplasm carbohydrate binding, glycoprotein binding, protein binding, ubiquitin-protein ligase activity Human FBXO7 IntAct UniProtKB {GO:0005515=PMID:22632967, GO:0043234=GO_REF:0000054, GO:0006511=PMID:10531035, GO:0008219=GO_REF:0000037, GO:0004842=PMID:10531035, GO:0005737=GO_REF:0000039, GO:0031647=PMID:15145941, GO:0000151=PMID:10531035, GO:0005634=GO_REF:0000039} Q9Y3I1 F-box only protein 7 protein 20130415 {GO:0005515=IPI, GO:0043234=IDA, GO:0006511=TAS, GO:0008219=IEA, GO:0004842=TAS, GO:0005737=IEA, GO:0031647=IDA, GO:0000151=TAS, GO:0005634=IEA} cell death, regulation of protein stability, ubiquitin-dependent protein catabolic process cytoplasm, nucleus, protein complex, ubiquitin ligase complex protein binding, ubiquitin-protein ligase activity Human UniProtKB:P63208 FBXO8 UniProtKB UniProtKB {GO:0005802=GO_REF:0000033, GO:0005086=GO_REF:0000029, GO:0006511=PMID:10945468, GO:0030054=GO_REF:0000033, GO:0030036=GO_REF:0000033, GO:0032012=GO_REF:0000002, GO:0000151=PMID:10945468, GO:0005634=GO_REF:0000033, GO:0016192=GO_REF:0000033} Q9NRD0 F-box only protein 8 protein 20021104 {GO:0005802=IBA, GO:0005086=NAS, GO:0006511=NAS, GO:0030054=IBA, GO:0030036=IBA, GO:0032012=IEA, GO:0000151=NAS, GO:0005634=IBA, GO:0016192=IBA} actin cytoskeleton organization, regulation of ARF protein signal transduction, ubiquitin-dependent protein catabolic process, vesicle-mediated transport cell junction, nucleus, trans-Golgi network, ubiquitin ligase complex ARF guanyl-nucleotide exchange factor activity Human FBXO9 UniProtKB UniProtKB {GO:0005515=PMID:23263282, GO:0032006=PMID:23263282, GO:0005737=PMID:23263282, GO:0004842=PMID:10531037, GO:0016567=PMID:23263282, GO:0000151=PMID:10531037, GO:0031146=PMID:23263282, GO:0019005=PMID:23263282} Q9UK97 F-box only protein 9 protein 20130125 {GO:0005515=IPI, GO:0032006=IMP, GO:0005737=IDA, GO:0004842=NAS, GO:0016567=IDA, GO:0000151=NAS, GO:0031146=IDA, GO:0019005=IDA} SCF-dependent proteasomal ubiquitin-dependent protein catabolic process, protein ubiquitination, regulation of TOR signaling cascade SCF ubiquitin ligase complex, cytoplasm, ubiquitin ligase complex protein binding, ubiquitin-protein ligase activity Human UniProtKB:O43156 FBXW10 null null {} null null null null {} null null null FBXW11 IntAct UniProtKB {GO:0000209=PMID:20347421, GO:0005515=PMID:22682247, GO:0005813=PMID:21399614, GO:0042347=GO_REF:0000019, GO:0004842=PMID:20347421, GO:0016567=PMID:16885022, GO:0000151=PMID:10531035, GO:0005634=GO_REF:0000024, GO:0031146=PMID:20347421, GO:0045862=PMID:16885022, GO:0005829=Reactome:REACT_118856, GO:0031648=PMID:16885022, GO:0007049=GO_REF:0000037, GO:0006470=GO_REF:0000024, GO:0042753=GO_REF:0000024, GO:0046983=GO_REF:0000002, GO:0043161=PMID:20347421, GO:0048511=GO_REF:0000037, GO:0045893=GO_REF:0000024, GO:0016055=GO_REF:0000037, GO:0045892=PMID:19966869, GO:0019005=PMID:20347421} Q9UKB1 F-box/WD repeat-containing protein 11 protein 20130415 {GO:0000209=IDA, GO:0005515=IPI, GO:0005813=IDA, GO:0042347=IEA, GO:0004842=IDA, GO:0016567=IDA, GO:0000151=NAS, GO:0005634=ISS, GO:0031146=IDA, GO:0045862=IMP, GO:0005829=TAS, GO:0031648=IMP, GO:0007049=IEA, GO:0006470=ISS, GO:0042753=ISS, GO:0046983=IEA, GO:0043161=IDA, GO:0048511=IEA, GO:0045893=ISS, GO:0016055=IEA, GO:0045892=IMP, GO:0019005=IDA} SCF-dependent proteasomal ubiquitin-dependent protein catabolic process, Wnt receptor signaling pathway, cell cycle, negative regulation of NF-kappaB import into nucleus, negative regulation of transcription, DNA-dependent, positive regulation of circadian rhythm, positive regulation of proteolysis, positive regulation of transcription, DNA-dependent, proteasomal ubiquitin-dependent protein catabolic process, protein dephosphorylation, protein destabilization, protein polyubiquitination, protein ubiquitination, rhythmic process SCF ubiquitin ligase complex, centrosome, cytosol, nucleus, ubiquitin ligase complex protein binding, protein dimerization activity, ubiquitin-protein ligase activity Human UniProtKB:P35222 FBXW2 GOC UniProtKB {GO:0005515=PMID:22632967, GO:0004842=PMID:10531035, GO:0005737=GO_REF:0000019, GO:0016567=PMID:10531035, GO:0006508=PMID:10531035, GO:0006464=PMID:10531035} Q9UKT8 F-box/WD repeat-containing protein 2 protein 20130413 {GO:0005515=IPI, GO:0004842=TAS, GO:0005737=IEA, GO:0016567=TAS, GO:0006508=TAS, GO:0006464=TAS} cellular protein modification process, protein ubiquitination, proteolysis cytoplasm protein binding, ubiquitin-protein ligase activity Human FBXW4 UniProtKB UniProtKB {GO:0003674=GO_REF:0000015, GO:0006511=PMID:10945468, GO:0051216=GO_REF:0000019, GO:0000151=PMID:10945468, GO:0002053=GO_REF:0000019, GO:0030326=PMID:10405324, GO:0016055=GO_REF:0000037, GO:0042733=GO_REF:0000019} P57775 F-box/WD repeat-containing protein 4 protein 20011009 {GO:0003674=ND, GO:0006511=NAS, GO:0051216=IEA, GO:0000151=NAS, GO:0002053=IEA, GO:0030326=NAS, GO:0016055=IEA, GO:0042733=IEA} Wnt receptor signaling pathway, cartilage development, embryonic digit morphogenesis, embryonic limb morphogenesis, positive regulation of mesenchymal cell proliferation, ubiquitin-dependent protein catabolic process ubiquitin ligase complex molecular_function Human FBXW5 IntAct UniProtKB {GO:0005515=PMID:22632967, GO:0051298=PMID:21725316, GO:0005737=PMID:21725316, GO:0016567=PMID:21725316, GO:0019901=PMID:21725316, GO:0043161=PMID:18381890, GO:0080008=PMID:18381890, GO:0031146=PMID:21725316, GO:0003824=GO_REF:0000002, GO:0019005=PMID:21725316} Q969U6 F-box/WD repeat-containing protein 5 protein 20130415 {GO:0005515=IPI, GO:0051298=IMP, GO:0005737=IDA, GO:0016567=IDA, GO:0019901=IPI, GO:0043161=IDA, GO:0080008=IDA, GO:0031146=IDA, GO:0003824=IEA, GO:0019005=IDA} SCF-dependent proteasomal ubiquitin-dependent protein catabolic process, centrosome duplication, proteasomal ubiquitin-dependent protein catabolic process, protein ubiquitination Cul4-RING ubiquitin ligase complex, SCF ubiquitin ligase complex, cytoplasm catalytic activity, protein binding, protein kinase binding Human UniProtKB:P63208 FBXW7 BHF-UCL UniProtKB {GO:0005515=PMID:17314511, GO:0016567=PMID:12354302, GO:0003700=GO_REF:0000019, GO:0030324=GO_REF:0000019, GO:0005783=GO_REF:0000019, GO:0032876=PMID:15917200, GO:0031146=PMID:15103331, GO:2000639=GO_REF:0000024, GO:0032880=GO_REF:0000024, GO:0007219=Reactome:REACT_118859, GO:0070374=PMID:20208556, GO:0001944=PMID:21123947, GO:0045746=GO_REF:0000024, GO:0010868=GO_REF:0000024, GO:0005794=GO_REF:0000019, GO:0045741=PMID:20208556, GO:0005730=GO_REF:0000039, GO:0050821=PMID:20208556, GO:2000346=GO_REF:0000024, GO:0055088=GO_REF:0000024, GO:0010883=GO_REF:0000024, GO:2000060=PMID:20208556, GO:0019048=GO_REF:0000037, GO:0007062=PMID:15917200, GO:0005654=Reactome:REACT_160209, GO:0001570=GO_REF:0000019, GO:0019005=PMID:15103331} Q969H0 F-box/WD repeat-containing protein 7 protein 20100127 {GO:0005515=IPI, GO:0016567=IDA, GO:0003700=IEA, GO:0030324=IEA, GO:0005783=IEA, GO:0032876=IMP, GO:0031146=IDA, GO:2000639=ISS, GO:0032880=ISS, GO:0007219=TAS, GO:0070374=IMP, GO:0001944=TAS, GO:0045746=ISS, GO:0010868=ISS, GO:0005794=IEA, GO:0045741=IDA, GO:0005730=IEA, GO:0050821=IDA, GO:2000346=ISS, GO:0055088=ISS, GO:0010883=ISS, GO:2000060=IDA, GO:0019048=IEA, GO:0007062=IMP, GO:0005654=TAS, GO:0001570=IEA, GO:0019005=IDA} Notch signaling pathway, SCF-dependent proteasomal ubiquitin-dependent protein catabolic process, lipid homeostasis, lung development, negative regulation of DNA endoreduplication, negative regulation of Notch signaling pathway, negative regulation of SREBP signaling pathway, negative regulation of hepatocyte proliferation, negative regulation of triglyceride biosynthetic process, positive regulation of ERK1 and ERK2 cascade, positive regulation of epidermal growth factor-activated receptor activity, positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process, protein stabilization, protein ubiquitination, regulation of lipid storage, regulation of protein localization, sister chromatid cohesion, vasculature development, vasculogenesis, virus-host interaction Golgi apparatus, SCF ubiquitin ligase complex, endoplasmic reticulum, nucleolus, nucleoplasm protein binding, sequence-specific DNA binding transcription factor activity Human FBXW8 IntAct UniProtKB {GO:0005515=PMID:17314511, GO:0048471=GO_REF:0000039, GO:0005794=GO_REF:0000039, GO:0060712=GO_REF:0000019, GO:0060716=GO_REF:0000019, GO:0019005=GO_REF:0000019} Q8N3Y1 F-box/WD repeat-containing protein 8 protein 20130415 {GO:0005515=IPI, GO:0048471=IEA, GO:0005794=IEA, GO:0060712=IEA, GO:0060716=IEA, GO:0019005=IEA} labyrinthine layer blood vessel development, spongiotrophoblast layer development Golgi apparatus, SCF ubiquitin ligase complex, perinuclear region of cytoplasm protein binding Human UniProtKB:P01106 FBXW9 IntAct UniProtKB {GO:0005515=PMID:19159283} Q5XUX1 F-box/WD repeat-containing protein 9 protein 20130415 {GO:0005515=IPI} protein binding Human UniProtKB:P63208 FCAMR UniProtKB UniProtKB {GO:0005886=GO_REF:0000039, GO:0016021=GO_REF:0000037} Q8WWV6 High affinity immunoglobulin alpha and immunoglobulin mu Fc receptor protein 20130413 {GO:0005886=IEA, GO:0016021=IEA} integral to membrane, plasma membrane Human UniProtKB-SubCell:SL-0039 FCAR HPA UniProtKB {GO:0006955=PMID:10835685, GO:0019862=GO_REF:0000037, GO:0005886=GO_REF:0000052, GO:0005887=PMID:2258698, GO:0005576=GO_REF:0000039} P24071 Immunoglobulin alpha Fc receptor protein 20090616 {GO:0006955=TAS, GO:0019862=IEA, GO:0005886=IDA, GO:0005887=TAS, GO:0005576=IEA} immune response extracellular region, integral to plasma membrane, plasma membrane IgA binding Human FCER1A PINC UniProtKB {GO:0001812=GO_REF:0000019, GO:0019370=GO_REF:0000019, GO:0045401=GO_REF:0000019, GO:0001820=GO_REF:0000019, GO:0045425=GO_REF:0000019, GO:0005886=PMID:1535625, GO:0050731=GO_REF:0000019, GO:0007257=GO_REF:0000019, GO:0043306=GO_REF:0000019, GO:0050850=GO_REF:0000019, GO:0019863=GO_REF:0000019, GO:0005887=GO_REF:0000019, GO:0019767=GO_REF:0000019, GO:0009897=GO_REF:0000019} P12319 High affinity immunoglobulin epsilon receptor subunit alpha protein 20030904 {GO:0001812=IEA, GO:0019370=IEA, GO:0045401=IEA, GO:0001820=IEA, GO:0045425=IEA, GO:0005886=TAS, GO:0050731=IEA, GO:0007257=IEA, GO:0043306=IEA, GO:0050850=IEA, GO:0019863=IEA, GO:0005887=IEA, GO:0019767=IEA, GO:0009897=IEA} activation of JUN kinase activity, leukotriene biosynthetic process, positive regulation of calcium-mediated signaling, positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, positive regulation of interleukin-3 biosynthetic process, positive regulation of mast cell degranulation, positive regulation of peptidyl-tyrosine phosphorylation, positive regulation of type I hypersensitivity, serotonin secretion external side of plasma membrane, integral to plasma membrane, plasma membrane IgE binding, IgE receptor activity Human FCER1G Reactome UniProtKB {GO:0001812=GO_REF:0000019, GO:0032755=GO_REF:0000019, GO:0033026=GO_REF:0000019, GO:0045576=GO_REF:0000019, GO:0016064=GO_REF:0000019, GO:0005886=Reactome:REACT_23800, GO:0032733=GO_REF:0000019, GO:0010543=GO_REF:0000019, GO:0050900=Reactome:REACT_12051, GO:0002554=GO_REF:0000019, GO:0019886=GO_REF:0000019, GO:0032998=GO_REF:0000019, GO:0050766=GO_REF:0000019, GO:0019863=GO_REF:0000019, GO:0019864=GO_REF:0000019, GO:0001798=GO_REF:0000019, GO:0019767=GO_REF:0000019, GO:0002283=GO_REF:0000019, GO:0042742=GO_REF:0000019, GO:0032765=GO_REF:0000019, GO:0032760=GO_REF:0000019, GO:0030593=GO_REF:0000019, GO:0042590=GO_REF:0000019, GO:0030168=Reactome:REACT_798, GO:0006911=GO_REF:0000019, GO:0001805=GO_REF:0000019, GO:0043306=GO_REF:0000019, GO:0007596=Reactome:REACT_604, GO:0007229=GO_REF:0000019, GO:0005887=GO_REF:0000019, GO:0002431=GO_REF:0000019, GO:0009897=GO_REF:0000019} P30273 High affinity immunoglobulin epsilon receptor subunit gamma protein 20130213 {GO:0001812=IEA, GO:0032755=IEA, GO:0033026=IEA, GO:0045576=IEA, GO:0016064=IEA, GO:0005886=TAS, GO:0032733=IEA, GO:0010543=IEA, GO:0050900=TAS, GO:0002554=IEA, GO:0019886=IEA, GO:0032998=IEA, GO:0050766=IEA, GO:0019863=IEA, GO:0019864=IEA, GO:0001798=IEA, GO:0019767=IEA, GO:0002283=IEA, GO:0042742=IEA, GO:0032765=IEA, GO:0032760=IEA, GO:0030593=IEA, GO:0042590=IEA, GO:0030168=TAS, GO:0006911=IEA, GO:0001805=IEA, GO:0043306=IEA, GO:0007596=TAS, GO:0007229=IEA, GO:0005887=IEA, GO:0002431=IEA, GO:0009897=IEA} Fc receptor mediated stimulatory signaling pathway, antigen processing and presentation of exogenous peptide antigen via MHC class I, antigen processing and presentation of exogenous peptide antigen via MHC class II, blood coagulation, defense response to bacterium, immunoglobulin mediated immune response, integrin-mediated signaling pathway, leukocyte migration, mast cell activation, negative regulation of mast cell apoptotic process, neutrophil activation involved in immune response, neutrophil chemotaxis, phagocytosis, engulfment, platelet activation, positive regulation of interleukin-10 production, positive regulation of interleukin-6 production, positive regulation of mast cell cytokine production, positive regulation of mast cell degranulation, positive regulation of phagocytosis, positive regulation of tumor necrosis factor production, positive regulation of type I hypersensitivity, positive regulation of type III hypersensitivity, positive regulation of type IIa hypersensitivity, regulation of platelet activation, serotonin secretion by platelet Fc-epsilon receptor I complex, external side of plasma membrane, integral to plasma membrane, plasma membrane IgE binding, IgE receptor activity, IgG binding Human FCER2 BHF-UCL UniProtKB {GO:0002925=GO_REF:0000019, GO:0019863=GO_REF:0000037, GO:0005178=PMID:2529542, GO:0051000=PMID:7544003, GO:0005887=PMID:2529542, GO:0051712=PMID:7544003, GO:0030246=GO_REF:0000002, GO:0005576=GO_REF:0000039, GO:0051770=PMID:7544003, GO:0009897=GO_REF:0000019, GO:0046872=GO_REF:0000037} P06734 Low affinity immunoglobulin epsilon Fc receptor protein 20080724 {GO:0002925=IEA, GO:0019863=IEA, GO:0005178=TAS, GO:0051000=IDA, GO:0005887=TAS, GO:0051712=IDA, GO:0030246=IEA, GO:0005576=IEA, GO:0051770=IDA, GO:0009897=IEA, GO:0046872=IEA} positive regulation of humoral immune response mediated by circulating immunoglobulin, positive regulation of killing of cells of other organism, positive regulation of nitric-oxide synthase activity, positive regulation of nitric-oxide synthase biosynthetic process external side of plasma membrane, extracellular region, integral to plasma membrane IgE binding, carbohydrate binding, integrin binding, metal ion binding Human FCGBP HPA UniProtKB {GO:0005515=PMID:19432394, GO:0005737=GO_REF:0000052, GO:0005576=GO_REF:0000039} Q9Y6R7 IgGFc-binding protein protein 20080205 {GO:0005515=IPI, GO:0005737=IDA, GO:0005576=IEA} cytoplasm, extracellular region protein binding Human FCGR1A BHF-UCL UniProtKB {GO:0005515=PMID:18322202, GO:0002474=Reactome:REACT_75820, GO:0005886=PMID:18322202, GO:0019221=Reactome:REACT_25229, GO:0050766=GO_REF:0000019, GO:0006955=PMID:10879688, GO:0019864=GO_REF:0000019, GO:0001798=GO_REF:0000019, GO:0042742=GO_REF:0000019, GO:0060333=Reactome:REACT_25078, GO:0042590=Reactome:REACT_111119, GO:0006910=GO_REF:0000019, GO:0006911=GO_REF:0000019, GO:0006898=GO_REF:0000019, GO:0001805=GO_REF:0000019, GO:0007165=PMID:10879688, GO:0031901=Reactome:REACT_111177, GO:0045087=Reactome:REACT_6802, GO:0002479=Reactome:REACT_111056, GO:0016021=GO_REF:0000037, GO:0005057=PMID:10879688, GO:0019770=GO_REF:0000019, GO:0030669=Reactome:REACT_111177, GO:0038096=Reactome:REACT_160123, GO:0001788=GO_REF:0000019, GO:0009897=GO_REF:0000019} P12314 High affinity immunoglobulin gamma Fc receptor I protein 20080926 {GO:0005515=IPI, GO:0002474=TAS, GO:0005886=IDA, GO:0019221=TAS, GO:0050766=IEA, GO:0006955=TAS, GO:0019864=IEA, GO:0001798=IEA, GO:0042742=IEA, GO:0060333=TAS, GO:0042590=TAS, GO:0006910=IEA, GO:0006911=IEA, GO:0006898=IEA, GO:0001805=IEA, GO:0007165=TAS, GO:0031901=TAS, GO:0045087=TAS, GO:0002479=TAS, GO:0016021=IEA, GO:0005057=TAS, GO:0019770=IEA, GO:0030669=TAS, GO:0038096=TAS, GO:0001788=IEA, GO:0009897=IEA} Fc-gamma receptor signaling pathway involved in phagocytosis, antibody-dependent cellular cytotoxicity, antigen processing and presentation of exogenous peptide antigen via MHC class I, antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent, antigen processing and presentation of peptide antigen via MHC class I, cytokine-mediated signaling pathway, defense response to bacterium, immune response, innate immune response, interferon-gamma-mediated signaling pathway, phagocytosis, engulfment, phagocytosis, recognition, positive regulation of phagocytosis, positive regulation of type III hypersensitivity, positive regulation of type IIa hypersensitivity, receptor-mediated endocytosis, signal transduction clathrin-coated endocytic vesicle membrane, early endosome membrane, external side of plasma membrane, integral to membrane, plasma membrane IgG binding, IgG receptor activity, protein binding, receptor signaling protein activity Human FCGR2A Reactome UniProtKB {GO:0005886=Reactome:REACT_160316, GO:0019864=GO_REF:0000037, GO:0045087=Reactome:REACT_6802, GO:0016021=GO_REF:0000037, GO:0038096=Reactome:REACT_160123} P12318 Low affinity immunoglobulin gamma Fc region receptor II-a protein 20120104 {GO:0005886=TAS, GO:0019864=IEA, GO:0045087=TAS, GO:0016021=IEA, GO:0038096=TAS} Fc-gamma receptor signaling pathway involved in phagocytosis, innate immune response integral to membrane, plasma membrane IgG binding Human FCGR2B IntAct UniProtKB {GO:0005515=PMID:17474147, GO:0007165=PMID:2142460, GO:0006955=PMID:2142460, GO:0005886=Reactome:REACT_11087, GO:0019864=GO_REF:0000037, GO:0019048=GO_REF:0000037, GO:0050776=Reactome:REACT_11152, GO:0016021=GO_REF:0000037} P31994 Low affinity immunoglobulin gamma Fc region receptor II-b protein 20130415 {GO:0005515=IPI, GO:0007165=TAS, GO:0006955=TAS, GO:0005886=TAS, GO:0019864=IEA, GO:0019048=IEA, GO:0050776=TAS, GO:0016021=IEA} immune response, regulation of immune response, signal transduction, virus-host interaction integral to membrane, plasma membrane IgG binding, protein binding Human UniProtKB:P19174 FCGR2C IntAct UniProtKB {GO:0005515=PMID:17785206, GO:0006955=PMID:2531080, GO:0005737=GO_REF:0000039, GO:0005886=GO_REF:0000039, GO:0019864=GO_REF:0000037, GO:0016021=PMID:2531080, GO:0004888=PMID:2531080} P31995 Low affinity immunoglobulin gamma Fc region receptor II-c protein 20130415 {GO:0005515=IPI, GO:0006955=NAS, GO:0005737=IEA, GO:0005886=IEA, GO:0019864=IEA, GO:0016021=NAS, GO:0004888=NAS} immune response cytoplasm, integral to membrane, plasma membrane IgG binding, protein binding, transmembrane signaling receptor activity Human UniProtKB:P02741 FCGR3A Reactome UniProtKB {GO:0006955=PMID:2138330, GO:0005886=Reactome:REACT_160316, GO:0019864=GO_REF:0000037, GO:0045087=Reactome:REACT_6802, GO:0050776=Reactome:REACT_11152, GO:0005576=GO_REF:0000039, GO:0016021=GO_REF:0000037, GO:0038096=Reactome:REACT_160123} P08637 Low affinity immunoglobulin gamma Fc region receptor III-A protein 20130228 {GO:0006955=TAS, GO:0005886=TAS, GO:0019864=IEA, GO:0045087=TAS, GO:0050776=TAS, GO:0005576=IEA, GO:0016021=IEA, GO:0038096=TAS} Fc-gamma receptor signaling pathway involved in phagocytosis, immune response, innate immune response, regulation of immune response extracellular region, integral to membrane, plasma membrane IgG binding Human FCGR3B PINC UniProtKB {GO:0006955=PMID:2139735, GO:0005886=GO_REF:0000039, GO:0019864=GO_REF:0000037, GO:0005576=GO_REF:0000039, GO:0031225=GO_REF:0000037} O75015 Low affinity immunoglobulin gamma Fc region receptor III-B protein 20030904 {GO:0006955=TAS, GO:0005886=IEA, GO:0019864=IEA, GO:0005576=IEA, GO:0031225=IEA} immune response anchored to membrane, extracellular region, plasma membrane IgG binding Human FCGRT UniProtKB UniProtKB {GO:0030881=GO_REF:0000019, GO:0006955=GO_REF:0000002, GO:0019864=PMID:7964511, GO:0002416=PMID:7964511, GO:0019882=GO_REF:0000002, GO:0042612=GO_REF:0000002, GO:0016021=GO_REF:0000037} P55899 IgG receptor FcRn large subunit p51 protein 20130307 {GO:0030881=IEA, GO:0006955=IEA, GO:0019864=IDA, GO:0002416=NAS, GO:0019882=IEA, GO:0042612=IEA, GO:0016021=IEA} IgG immunoglobulin transcytosis in epithelial cells mediated by FcRn immunoglobulin receptor, antigen processing and presentation, immune response MHC class I protein complex, integral to membrane IgG binding, beta-2-microglobulin binding Human FCHO1 MGI UniProtKB {GO:0072583=PMID:20448150, GO:0005905=PMID:22484487, GO:0005886=PMID:20448150, GO:0035612=PMID:22484487, GO:0030136=PMID:20448150, GO:0048268=PMID:20448150} O14526 FCH domain only protein 1 protein 20120730 {GO:0072583=IMP, GO:0005905=IDA, GO:0005886=IDA, GO:0035612=IDA, GO:0030136=IDA, GO:0048268=IMP} clathrin coat assembly, clathrin-mediated endocytosis clathrin-coated vesicle, coated pit, plasma membrane AP-2 adaptor complex binding Human FCHO2 IntAct UniProtKB {GO:0005515=PMID:22323290, GO:0072583=PMID:20448150, GO:0005905=PMID:22484487, GO:0005886=GO_REF:0000024, GO:0030136=PMID:21762413, GO:0001786=GO_REF:0000024, GO:0005546=GO_REF:0000024, GO:0035091=GO_REF:0000024, GO:0072659=GO_REF:0000024, GO:0010324=GO_REF:0000024, GO:0048268=PMID:20448150} Q0JRZ9 FCH domain only protein 2 protein 20130415 {GO:0005515=IPI, GO:0072583=IMP, GO:0005905=IDA, GO:0005886=ISS, GO:0030136=IDA, GO:0001786=ISS, GO:0005546=ISS, GO:0035091=ISS, GO:0072659=ISS, GO:0010324=ISS, GO:0048268=IMP} clathrin coat assembly, clathrin-mediated endocytosis, membrane invagination, protein localization to plasma membrane clathrin-coated vesicle, coated pit, plasma membrane phosphatidylinositol binding, phosphatidylinositol-4,5-bisphosphate binding, phosphatidylserine binding, protein binding Human UniProtKB:P98078 FCHSD1 null null {} null null null null {} null null null FCHSD2 IntAct UniProtKB {GO:0005515=PMID:18654987} O94868 FCH and double SH3 domains protein 2 protein 20130415 {GO:0005515=IPI} protein binding Human UniProtKB:P55072 FCN1 PINC UniProtKB {GO:0005581=GO_REF:0000037, GO:0045087=GO_REF:0000037, GO:0005509=PMID:8576206, GO:0030246=PMID:8576206, GO:0003823=PMID:8576206, GO:0008228=PMID:8576206} O00602 Ficolin-1 protein 20030904 {GO:0005581=IEA, GO:0045087=IEA, GO:0005509=TAS, GO:0030246=TAS, GO:0003823=TAS, GO:0008228=TAS} innate immune response, opsonization collagen antigen binding, calcium ion binding, carbohydrate binding Human FCN2 PINC UniProtKB {GO:0005581=GO_REF:0000037, GO:0005509=PMID:8576206, GO:0030246=PMID:8576206, GO:0003823=PMID:8576206, GO:0008228=PMID:8576206, GO:0048306=PMID:12421953, GO:0001867=GO_REF:0000037} Q15485 Ficolin-2 protein 20031106 {GO:0005581=IEA, GO:0005509=TAS, GO:0030246=TAS, GO:0003823=TAS, GO:0008228=TAS, GO:0048306=IPI, GO:0001867=IEA} complement activation, lectin pathway, opsonization collagen antigen binding, calcium ion binding, calcium-dependent protein binding, carbohydrate binding Human FCN3 PINC UniProtKB {GO:0005515=PMID:11907111, GO:0005581=GO_REF:0000037, GO:0030246=PMID:9694814, GO:0005576=PMID:14718574, GO:0001867=PMID:11907111} O75636 Ficolin-3 protein 20031119 {GO:0005515=IPI, GO:0005581=IEA, GO:0030246=TAS, GO:0005576=NAS, GO:0001867=IDA} complement activation, lectin pathway collagen, extracellular region carbohydrate binding, protein binding Human FCRL3 UniProtKB UniProtKB {GO:0005886=GO_REF:0000039, GO:0016021=GO_REF:0000037} Q96P31 Fc receptor-like protein 3 protein 20130413 {GO:0005886=IEA, GO:0016021=IEA} integral to membrane, plasma membrane Human UniProtKB-SubCell:SL-0039 FCRLB MGI UniProtKB {GO:0005737=PMID:15815692, GO:0005783=GO_REF:0000039} Q6BAA4 Fc receptor-like B protein 20091111 {GO:0005737=IDA, GO:0005783=IEA} cytoplasm, endoplasmic reticulum Human FDFT1 HPA UniProtKB {GO:0006695=Reactome:REACT_9405, GO:0008610=GO_REF:0000002, GO:0006694=PMID:8474436, GO:0009058=GO_REF:0000002, GO:0051996=GO_REF:0000003, GO:0005783=GO_REF:0000052, GO:0044281=Reactome:REACT_111217, GO:0008299=GO_REF:0000037, GO:0043231=GO_REF:0000019, GO:0045338=GO_REF:0000019, GO:0016491=GO_REF:0000037, GO:0005789=Reactome:REACT_115945, GO:0016021=GO_REF:0000037, GO:0044255=Reactome:REACT_22279, GO:0016740=GO_REF:0000002, GO:0004310=Reactome:REACT_9512} P37268 Squalene synthase protein 20080818 {GO:0006695=TAS, GO:0008610=IEA, GO:0006694=TAS, GO:0009058=IEA, GO:0051996=IEA, GO:0005783=IDA, GO:0044281=TAS, GO:0008299=IEA, GO:0043231=IEA, GO:0045338=IEA, GO:0016491=IEA, GO:0005789=TAS, GO:0016021=IEA, GO:0044255=TAS, GO:0016740=IEA, GO:0004310=TAS} biosynthetic process, cellular lipid metabolic process, cholesterol biosynthetic process, farnesyl diphosphate metabolic process, isoprenoid biosynthetic process, lipid biosynthetic process, small molecule metabolic process, steroid biosynthetic process endoplasmic reticulum, endoplasmic reticulum membrane, integral to membrane, intracellular membrane-bounded organelle farnesyl-diphosphate farnesyltransferase activity, oxidoreductase activity, squalene synthase activity, transferase activity Human FDPS HPA UniProtKB {GO:0006695=Reactome:REACT_9405, GO:0005730=GO_REF:0000052, GO:0004337=GO_REF:0000003, GO:0005634=GO_REF:0000052, GO:0044281=Reactome:REACT_111217, GO:0008299=GO_REF:0000038, GO:0046872=GO_REF:0000037, GO:0005829=Reactome:REACT_147807, GO:0005739=GO_REF:0000019, GO:0005737=GO_REF:0000052, GO:0019048=GO_REF:0000037, GO:0045337=GO_REF:0000041, GO:0004161=GO_REF:0000003, GO:0033384=GO_REF:0000041, GO:0016740=GO_REF:0000038} P14324 Farnesyl pyrophosphate synthase protein 20101115 {GO:0006695=TAS, GO:0005730=IDA, GO:0004337=IEA, GO:0005634=IDA, GO:0044281=TAS, GO:0008299=IEA, GO:0046872=IEA, GO:0005829=TAS, GO:0005739=IEA, GO:0005737=IDA, GO:0019048=IEA, GO:0045337=IEA, GO:0004161=IEA, GO:0033384=IEA, GO:0016740=IEA} cholesterol biosynthetic process, farnesyl diphosphate biosynthetic process, geranyl diphosphate biosynthetic process, isoprenoid biosynthetic process, small molecule metabolic process, virus-host interaction cytoplasm, cytosol, mitochondrion, nucleolus, nucleus dimethylallyltranstransferase activity, geranyltranstransferase activity, metal ion binding, transferase activity Human FDX1 HPA UniProtKB {GO:0005739=GO_REF:0000052, GO:0006694=GO_REF:0000037, GO:0005506=PMID:2969697, GO:0051537=PMID:21636783, GO:0005759=Reactome:REACT_150385, GO:0009055=PMID:21636783, GO:0042446=PMID:21636783, GO:0044281=Reactome:REACT_111217, GO:0022900=GO_REF:0000037, GO:0008203=PMID:21636783} P10109 Adrenodoxin, mitochondrial protein 20110516 {GO:0005739=IDA, GO:0006694=IEA, GO:0005506=TAS, GO:0051537=IDA, GO:0005759=TAS, GO:0009055=IDA, GO:0042446=IDA, GO:0044281=TAS, GO:0022900=IEA, GO:0008203=IDA} cholesterol metabolic process, electron transport chain, hormone biosynthetic process, small molecule metabolic process, steroid biosynthetic process mitochondrial matrix, mitochondrion 2 iron, 2 sulfur cluster binding, electron carrier activity, iron ion binding Human FDX1L Reactome UniProtKB {GO:0051537=GO_REF:0000037, GO:0005759=Reactome:REACT_150385, GO:0009055=GO_REF:0000002, GO:0044281=Reactome:REACT_111217, GO:0022900=GO_REF:0000037, GO:0046872=GO_REF:0000037} Q6P4F2 Adrenodoxin-like protein, mitochondrial protein 20120702 {GO:0051537=IEA, GO:0005759=TAS, GO:0009055=IEA, GO:0044281=TAS, GO:0022900=IEA, GO:0046872=IEA} electron transport chain, small molecule metabolic process mitochondrial matrix 2 iron, 2 sulfur cluster binding, electron carrier activity, metal ion binding Human FDXACB1 InterPro UniProtKB {GO:0000287=GO_REF:0000002, GO:0000049=GO_REF:0000002, GO:0006432=GO_REF:0000002, GO:0004826=GO_REF:0000002, GO:0005524=GO_REF:0000002, GO:0008033=GO_REF:0000002} Q9BRP7 Ferredoxin-fold anticodon-binding domain-containing protein 1 protein 20130413 {GO:0000287=IEA, GO:0000049=IEA, GO:0006432=IEA, GO:0004826=IEA, GO:0005524=IEA, GO:0008033=IEA} phenylalanyl-tRNA aminoacylation, tRNA processing ATP binding, magnesium ion binding, phenylalanine-tRNA ligase activity, tRNA binding Human InterPro:IPR005121 FDXR IntAct UniProtKB {GO:0005515=PMID:18319262, GO:0006694=PMID:1863359, GO:0005743=GO_REF:0000019, GO:0044281=Reactome:REACT_111217, GO:0006091=PMID:2845396, GO:0070402=GO_REF:0000019, GO:0070995=GO_REF:0000019, GO:0005739=PMID:2845396, GO:0004324=PMID:2845396, GO:0005759=Reactome:REACT_150376, GO:0015039=GO_REF:0000019, GO:0016491=GO_REF:0000038, GO:0022900=GO_REF:0000037, GO:0008203=GO_REF:0000041, GO:0055114=PMID:2845396} P22570 NADPH:adrenodoxin oxidoreductase, mitochondrial protein 20130415 {GO:0005515=IPI, GO:0006694=TAS, GO:0005743=IEA, GO:0044281=TAS, GO:0006091=TAS, GO:0070402=IEA, GO:0070995=IEA, GO:0005739=TAS, GO:0004324=TAS, GO:0005759=TAS, GO:0015039=IEA, GO:0016491=IEA, GO:0022900=IEA, GO:0008203=IEA, GO:0055114=TAS} NADPH oxidation, cholesterol metabolic process, electron transport chain, generation of precursor metabolites and energy, oxidation-reduction process, small molecule metabolic process, steroid biosynthetic process mitochondrial inner membrane, mitochondrial matrix, mitochondrion NADPH binding, NADPH-adrenodoxin reductase activity, ferredoxin-NADP+ reductase activity, oxidoreductase activity, protein binding Human UniProtKB:P49789 FECH BHF-UCL UniProtKB {GO:0005515=PMID:15123683, GO:0051537=GO_REF:0000037, GO:0005743=GO_REF:0000039, GO:0044281=Reactome:REACT_111217, GO:0006091=PMID:1729699, GO:0010999=GO_REF:0000019, GO:0034379=GO_REF:0000019, GO:0055072=GO_REF:0000019, GO:0008198=PMID:1729699, GO:0004325=PMID:15123683, GO:0006783=Reactome:REACT_9465, GO:0006778=Reactome:REACT_9431, GO:0005759=Reactome:REACT_9461, GO:0030218=GO_REF:0000019, GO:0030350=GO_REF:0000019, GO:0046984=GO_REF:0000019, GO:0009416=PMID:1376018, GO:0046501=PMID:15123683, GO:0009589=GO_REF:0000019, GO:0008203=GO_REF:0000019, GO:0020037=GO_REF:0000019} P22830 Ferrochelatase, mitochondrial protein 20080912 {GO:0005515=IPI, GO:0051537=IEA, GO:0005743=IEA, GO:0044281=TAS, GO:0006091=TAS, GO:0010999=IEA, GO:0034379=IEA, GO:0055072=IEA, GO:0008198=TAS, GO:0004325=IDA, GO:0006783=TAS, GO:0006778=TAS, GO:0005759=TAS, GO:0030218=IEA, GO:0030350=IEA, GO:0046984=IEA, GO:0009416=TAS, GO:0046501=IDA, GO:0009589=IEA, GO:0008203=IEA, GO:0020037=IEA} cholesterol metabolic process, detection of UV, erythrocyte differentiation, generation of precursor metabolites and energy, heme biosynthetic process, iron ion homeostasis, porphyrin-containing compound metabolic process, protoporphyrinogen IX metabolic process, regulation of eIF2 alpha phosphorylation by heme, regulation of hemoglobin biosynthetic process, response to light stimulus, small molecule metabolic process, very-low-density lipoprotein particle assembly mitochondrial inner membrane, mitochondrial matrix 2 iron, 2 sulfur cluster binding, ferrochelatase activity, ferrous iron binding, heme binding, iron-responsive element binding, protein binding Human FEM1A UniProtKB UniProtKB {GO:0004842=GO_REF:0000024, GO:0005737=GO_REF:0000039, GO:0050728=PMID:16424369, GO:0051438=GO_REF:0000024, GO:0031867=PMID:16424369} Q9BSK4 Protein fem-1 homolog A protein 20111220 {GO:0004842=ISS, GO:0005737=IEA, GO:0050728=IDA, GO:0051438=ISS, GO:0031867=IPI} negative regulation of inflammatory response, regulation of ubiquitin-protein ligase activity cytoplasm EP4 subtype prostaglandin E2 receptor binding, ubiquitin-protein ligase activity Human FEM1B HPA UniProtKB {GO:0005515=PMID:17003112, GO:0004842=PMID:15601820, GO:0016567=GO_REF:0000019, GO:0060743=GO_REF:0000019, GO:2000001=PMID:19330022, GO:0005730=GO_REF:0000052, GO:0006915=GO_REF:0000037, GO:0051438=PMID:15601820, GO:0042981=PMID:10542291, GO:0005634=GO_REF:0000052, GO:0005123=PMID:10542291, GO:0006917=PMID:10623617, GO:0060442=GO_REF:0000019, GO:0005737=PMID:19330022} Q9UK73 Protein fem-1 homolog B protein 20110516 {GO:0005515=IPI, GO:0004842=IMP, GO:0016567=IEA, GO:0060743=IEA, GO:2000001=IMP, GO:0005730=IDA, GO:0006915=IEA, GO:0051438=IMP, GO:0042981=IMP, GO:0005634=IDA, GO:0005123=IMP, GO:0006917=NAS, GO:0060442=IEA, GO:0005737=IDA} apoptotic process, branching involved in prostate gland morphogenesis, epithelial cell maturation involved in prostate gland development, induction of apoptosis, protein ubiquitination, regulation of DNA damage checkpoint, regulation of apoptotic process, regulation of ubiquitin-protein ligase activity cytoplasm, nucleolus, nucleus death receptor binding, protein binding, ubiquitin-protein ligase activity NOT Human FEM1C UniPathway UniProtKB {GO:0005737=GO_REF:0000039, GO:0016567=GO_REF:0000041} Q96JP0 Protein fem-1 homolog C protein 20130413 {GO:0005737=IEA, GO:0016567=IEA} protein ubiquitination cytoplasm Human UniPathway:UPA00143 FEN1 HPA UniProtKB {GO:0005515=PMID:18499658, GO:0009650=PMID:8007985, GO:0008409=PMID:7961795, GO:0005634=GO_REF:0000052, GO:0006302=PMID:8131753, GO:0005739=PMID:18995831, GO:0000084=Reactome:REACT_899, GO:0006271=Reactome:REACT_932, GO:0004527=PMID:9778254, GO:0003690=PMID:8131753, GO:0000723=Reactome:REACT_7970, GO:0004523=PMID:7961795, GO:0000722=Reactome:REACT_8027, GO:0048256=GO_REF:0000019, GO:0007613=GO_REF:0000019, GO:0008309=PMID:8131753, GO:0030145=GO_REF:0000019, GO:0000287=GO_REF:0000020, GO:0048015=PMID:15504738, GO:0005730=GO_REF:0000039, GO:0003677=PMID:11986308, GO:0006260=PMID:15504738, GO:0003684=PMID:8007985, GO:0004518=GO_REF:0000002, GO:0006281=Reactome:REACT_216, GO:0004519=PMID:8131753, GO:0006284=Reactome:REACT_1104, GO:0005654=Reactome:REACT_7975, GO:0017108=PMID:18995831, GO:0043137=PMID:18995831, GO:0000278=Reactome:REACT_152, GO:0032201=Reactome:REACT_7961} P39748 Flap endonuclease 1 protein 20080818 {GO:0005515=IPI, GO:0009650=TAS, GO:0008409=IDA, GO:0005634=IDA, GO:0006302=TAS, GO:0005739=IDA, GO:0000084=TAS, GO:0006271=TAS, GO:0004527=TAS, GO:0003690=TAS, GO:0000723=TAS, GO:0004523=IDA, GO:0000722=TAS, GO:0048256=IEA, GO:0007613=IEA, GO:0008309=TAS, GO:0030145=IEA, GO:0000287=IEA, GO:0048015=NAS, GO:0005730=IEA, GO:0003677=IMP, GO:0006260=NAS, GO:0003684=TAS, GO:0004518=IEA, GO:0006281=TAS, GO:0004519=TAS, GO:0006284=TAS, GO:0005654=TAS, GO:0017108=IDA, GO:0043137=IDA, GO:0000278=TAS, GO:0032201=TAS} DNA repair, DNA replication, DNA replication, removal of RNA primer, DNA strand elongation involved in DNA replication, S phase of mitotic cell cycle, UV protection, base-excision repair, double-strand break repair, memory, mitotic cell cycle, phosphatidylinositol-mediated signaling, telomere maintenance, telomere maintenance via recombination, telomere maintenance via semi-conservative replication mitochondrion, nucleolus, nucleoplasm, nucleus 5'-3' exonuclease activity, 5'-flap endonuclease activity, DNA binding, damaged DNA binding, double-stranded DNA binding, double-stranded DNA specific exodeoxyribonuclease activity, endonuclease activity, exonuclease activity, flap endonuclease activity, magnesium ion binding, manganese ion binding, nuclease activity, protein binding, ribonuclease H activity Human FER HPA UniProtKB {GO:0005154=PMID:21518868, GO:0000790=PMID:1990274, GO:0030054=PMID:12972546, GO:0042503=PMID:19147545, GO:0019221=PMID:9722593, GO:0050904=GO_REF:0000024, GO:0010762=GO_REF:0000019, GO:0046777=PMID:7623846, GO:0030838=PMID:19738202, GO:0006935=GO_REF:0000019, GO:0016301=GO_REF:0000038, GO:0032496=GO_REF:0000024, GO:0034446=GO_REF:0000024, GO:0070102=PMID:19147545, GO:0005938=GO_REF:0000039, GO:0017137=GO_REF:0000019, GO:0032869=GO_REF:0000024, GO:0036006=PMID:9722593, GO:0030335=PMID:19738202, GO:0045296=GO_REF:0000019, GO:0019901=GO_REF:0000019, GO:0045295=GO_REF:0000019, GO:0031532=GO_REF:0000024, GO:0018108=PMID:12972546, GO:0035426=GO_REF:0000024, GO:0038028=GO_REF:0000024, GO:0030027=PMID:19738202, GO:0042058=PMID:21518868, GO:0031234=PMID:19738202, GO:0044331=GO_REF:0000024, GO:0000278=PMID:22223638, GO:0038095=GO_REF:0000024, GO:0038109=GO_REF:0000024, GO:0008284=PMID:20111072, GO:0008283=PMID:22223638, GO:0033007=GO_REF:0000024, GO:0005634=PMID:19147545, GO:0015629=PMID:19738202, GO:0036119=GO_REF:0000024, GO:0005829=Reactome:REACT_111221, GO:0008289=PMID:19738202, GO:0010591=PMID:19738202, GO:0035556=PMID:2209086, GO:0005737=GO_REF:0000052, GO:0051092=PMID:21518868, GO:0015630=PMID:12972546, GO:0000226=PMID:12972546, GO:0003779=GO_REF:0000019, GO:0005524=GO_REF:0000037, GO:0034614=GO_REF:0000024, GO:0006468=PMID:2725517, GO:0008157=GO_REF:0000019, GO:0001932=GO_REF:0000024, GO:0048008=GO_REF:0000024, GO:0004713=PMID:2725517, GO:0004715=PMID:12972546} P16591 Tyrosine-protein kinase Fer protein 20080205 {GO:0005154=IDA, GO:0000790=IDA, GO:0030054=IDA, GO:0042503=IDA, GO:0019221=IMP, GO:0050904=ISS, GO:0010762=IEA, GO:0046777=IDA, GO:0030838=IMP, GO:0006935=IEA, GO:0016301=IEA, GO:0032496=ISS, GO:0034446=ISS, GO:0070102=IMP, GO:0005938=IEA, GO:0017137=IEA, GO:0032869=ISS, GO:0036006=IMP, GO:0030335=IMP, GO:0045296=IEA, GO:0019901=IEA, GO:0045295=IEA, GO:0031532=ISS, GO:0018108=IDA, GO:0035426=ISS, GO:0038028=ISS, GO:0030027=IDA, GO:0042058=IMP, GO:0031234=IDA, GO:0044331=ISS, GO:0000278=IMP, GO:0038095=ISS, GO:0038109=ISS, GO:0008284=TAS, GO:0008283=IMP, GO:0033007=ISS, GO:0005634=IDA, GO:0015629=IDA, GO:0036119=ISS, GO:0005829=TAS, GO:0008289=IDA, GO:0010591=IDA, GO:0035556=TAS, GO:0005737=IDA, GO:0051092=IMP, GO:0015630=IDA, GO:0000226=IMP, GO:0003779=IEA, GO:0005524=IEA, GO:0034614=ISS, GO:0006468=TAS, GO:0008157=IEA, GO:0001932=ISS, GO:0048008=ISS, GO:0004713=TAS, GO:0004715=IDA} Fc-epsilon receptor signaling pathway, Kit signaling pathway, actin cytoskeleton reorganization, cell proliferation, cell-cell adhesion mediated by cadherin, cellular response to insulin stimulus, cellular response to macrophage colony-stimulating factor stimulus, cellular response to reactive oxygen species, chemotaxis, cytokine-mediated signaling pathway, diapedesis, extracellular matrix-cell signaling, insulin receptor signaling pathway via phosphatidylinositol 3-kinase cascade, interleukin-6-mediated signaling pathway, intracellular signal transduction, microtubule cytoskeleton organization, mitotic cell cycle, negative regulation of mast cell activation involved in immune response, peptidyl-tyrosine phosphorylation, platelet-derived growth factor receptor signaling pathway, positive regulation of NF-kappaB transcription factor activity, positive regulation of actin filament polymerization, positive regulation of cell migration, positive regulation of cell proliferation, protein autophosphorylation, protein phosphorylation, regulation of epidermal growth factor receptor signaling pathway, regulation of fibroblast migration, regulation of lamellipodium assembly, regulation of protein phosphorylation, response to lipopolysaccharide, response to platelet-derived growth factor stimulus, substrate adhesion-dependent cell spreading, tyrosine phosphorylation of Stat3 protein actin cytoskeleton, cell cortex, cell junction, cytoplasm, cytosol, extrinsic to internal side of plasma membrane, lamellipodium, microtubule cytoskeleton, nuclear chromatin, nucleus ATP binding, Rab GTPase binding, actin binding, cadherin binding, epidermal growth factor receptor binding, gamma-catenin binding, kinase activity, lipid binding, non-membrane spanning protein tyrosine kinase activity, protein kinase binding, protein phosphatase 1 binding, protein tyrosine kinase activity Human FER1L6 UniProtKB UniProtKB {GO:0016021=GO_REF:0000037} Q2WGJ9 Fer-1-like protein 6 protein 20130413 {GO:0016021=IEA} integral to membrane Human UniProtKB-KW:KW-0812 FERD3L UniProtKB UniProtKB {GO:0046983=GO_REF:0000002, GO:0005634=GO_REF:0000024, GO:0045892=GO_REF:0000024, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q96RJ6 Fer3-like protein protein 20080326 {GO:0046983=IEA, GO:0005634=ISS, GO:0045892=ISS, GO:0003677=IEA, GO:0006351=IEA} negative regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus DNA binding, protein dimerization activity Human UniProtKB:Q923Z4 FERMT1 UniProtKB UniProtKB {GO:0090162=PMID:17012746, GO:0051546=PMID:17012746, GO:0030054=PMID:17012746, GO:0031941=GO_REF:0000019, GO:0005543=GO_REF:0000002, GO:0032587=GO_REF:0000039, GO:0007155=PMID:17012746, GO:0043616=PMID:17012746, GO:0005925=GO_REF:0000039, GO:0005829=PMID:17012746} Q9BQL6 Fermitin family homolog 1 protein 20100122 {GO:0090162=IDA, GO:0051546=IDA, GO:0030054=IDA, GO:0031941=IEA, GO:0005543=IEA, GO:0032587=IEA, GO:0007155=IDA, GO:0043616=IDA, GO:0005925=IEA, GO:0005829=IDA} cell adhesion, establishment of epithelial cell polarity, keratinocyte migration, keratinocyte proliferation cell junction, cytosol, filamentous actin, focal adhesion, ruffle membrane phospholipid binding Human FERMT2 HPA UniProtKB {GO:0001725=GO_REF:0000019, GO:0030036=GO_REF:0000029, GO:0034329=Reactome:REACT_20676, GO:0008360=GO_REF:0000037, GO:0005730=GO_REF:0000052, GO:0005547=PMID:22030399, GO:0005634=GO_REF:0000052, GO:0072657=GO_REF:0000024, GO:0005829=Reactome:REACT_20555, GO:0033622=PMID:22030399, GO:0031234=PMID:21325030, GO:0005737=PMID:22699938, GO:0031941=GO_REF:0000019, GO:0005543=GO_REF:0000002, GO:0007160=GO_REF:0000024, GO:0007229=PMID:21325030, GO:0048041=GO_REF:0000024, GO:0034446=GO_REF:0000024, GO:0007179=PMID:21325030, GO:0016055=PMID:22699938, GO:0005856=GO_REF:0000002, GO:0005925=GO_REF:0000052, GO:0005938=GO_REF:0000039} Q96AC1 Fermitin family homolog 2 protein 20110516 {GO:0001725=IEA, GO:0030036=NAS, GO:0034329=TAS, GO:0008360=IEA, GO:0005730=IDA, GO:0005547=IDA, GO:0005634=IDA, GO:0072657=ISS, GO:0005829=TAS, GO:0033622=IMP, GO:0031234=IDA, GO:0005737=IDA, GO:0031941=IEA, GO:0005543=IEA, GO:0007160=ISS, GO:0007229=IMP, GO:0048041=ISS, GO:0034446=ISS, GO:0007179=IMP, GO:0016055=IMP, GO:0005856=IEA, GO:0005925=IDA, GO:0005938=IEA} Wnt receptor signaling pathway, actin cytoskeleton organization, cell junction assembly, cell-matrix adhesion, focal adhesion assembly, integrin activation, integrin-mediated signaling pathway, protein localization to membrane, regulation of cell shape, substrate adhesion-dependent cell spreading, transforming growth factor beta receptor signaling pathway cell cortex, cytoplasm, cytoskeleton, cytosol, extrinsic to internal side of plasma membrane, filamentous actin, focal adhesion, nucleolus, nucleus, stress fiber phosphatidylinositol-3,4,5-trisphosphate binding, phospholipid binding Human FERMT3 UniProtKB UniProtKB {GO:0070527=GO_REF:0000024, GO:0030054=GO_REF:0000037, GO:0005543=GO_REF:0000002, GO:0005178=GO_REF:0000024, GO:0007159=PMID:19234460, GO:0002102=GO_REF:0000024, GO:0033632=PMID:19234463, GO:0042995=GO_REF:0000037, GO:0033622=PMID:19234463} Q86UX7 Fermitin family homolog 3 protein 20091113 {GO:0070527=ISS, GO:0030054=IEA, GO:0005543=IEA, GO:0005178=ISS, GO:0007159=IMP, GO:0002102=ISS, GO:0033632=IMP, GO:0042995=IEA, GO:0033622=IMP} integrin activation, leukocyte cell-cell adhesion, platelet aggregation, regulation of cell-cell adhesion mediated by integrin cell junction, cell projection, podosome integrin binding, phospholipid binding Human FES Reactome UniProtKB {GO:0008283=PMID:6264598, GO:0008360=PMID:18046454, GO:2000145=PMID:18046454, GO:2000251=PMID:15302586, GO:0030155=PMID:11509660, GO:0005829=Reactome:REACT_111221, GO:0005737=PMID:11339827, GO:0046777=PMID:7687763, GO:0045639=PMID:2656706, GO:0007411=Reactome:REACT_18266, GO:0042127=PMID:11509660, GO:0015630=PMID:15485904, GO:0060627=PMID:11339827, GO:0034987=PMID:19001085, GO:0043304=PMID:19001085, GO:0031116=PMID:15485904, GO:0005794=GO_REF:0000039, GO:0007275=PMID:6264598, GO:0018108=PMID:11509660, GO:0031410=PMID:11339827, GO:0005524=GO_REF:0000037, GO:0031234=PMID:18046454, GO:0004672=GO_REF:0000019, GO:0010976=PMID:15302586, GO:0016023=GO_REF:0000039, GO:0006468=PMID:6183005, GO:0045595=PMID:15302586, GO:0004713=PMID:11509660, GO:0035091=PMID:19001085, GO:0004715=PMID:15485904, GO:0005925=PMID:18046454} P07332 Tyrosine-protein kinase Fes/Fps protein 20090515 {GO:0008283=TAS, GO:0008360=IMP, GO:2000145=IMP, GO:2000251=IMP, GO:0030155=IMP, GO:0005829=TAS, GO:0005737=IDA, GO:0046777=IDA, GO:0045639=IMP, GO:0007411=TAS, GO:0042127=IMP, GO:0015630=IDA, GO:0060627=TAS, GO:0034987=IDA, GO:0043304=IMP, GO:0031116=IMP, GO:0005794=IEA, GO:0007275=TAS, GO:0018108=IDA, GO:0031410=IDA, GO:0005524=IEA, GO:0031234=IDA, GO:0004672=IEA, GO:0010976=IMP, GO:0016023=IEA, GO:0006468=TAS, GO:0045595=IMP, GO:0004713=IDA, GO:0035091=IDA, GO:0004715=IDA, GO:0005925=IDA} axon guidance, cell proliferation, multicellular organismal development, peptidyl-tyrosine phosphorylation, positive regulation of actin cytoskeleton reorganization, positive regulation of microtubule polymerization, positive regulation of myeloid cell differentiation, positive regulation of neuron projection development, protein autophosphorylation, protein phosphorylation, regulation of cell adhesion, regulation of cell differentiation, regulation of cell motility, regulation of cell proliferation, regulation of cell shape, regulation of mast cell degranulation, regulation of vesicle-mediated transport Golgi apparatus, cytoplasm, cytoplasmic membrane-bounded vesicle, cytoplasmic vesicle, cytosol, extrinsic to internal side of plasma membrane, focal adhesion, microtubule cytoskeleton ATP binding, immunoglobulin receptor binding, non-membrane spanning protein tyrosine kinase activity, phosphatidylinositol binding, protein kinase activity, protein tyrosine kinase activity Human FETUB UniProtKB UniProtKB {GO:0003674=GO_REF:0000015, GO:0008150=GO_REF:0000015, GO:0004869=GO_REF:0000002, GO:0005576=GO_REF:0000029, GO:0005615=GO_REF:0000002} Q9UGM5 Fetuin-B protein 20061026 {GO:0003674=ND, GO:0008150=ND, GO:0004869=IEA, GO:0005576=NAS, GO:0005615=IEA} biological_process extracellular region, extracellular space cysteine-type endopeptidase inhibitor activity, molecular_function Human FEZ1 HPA UniProtKB {GO:0005515=PMID:16169070, GO:0030424=GO_REF:0000019, GO:0005813=GO_REF:0000019, GO:0005886=GO_REF:0000039, GO:0043015=GO_REF:0000019, GO:0005874=GO_REF:0000037, GO:0030425=GO_REF:0000019, GO:0007399=PMID:9096408, GO:0051654=GO_REF:0000019, GO:0005737=GO_REF:0000052, GO:0047485=GO_REF:0000019, GO:0071363=GO_REF:0000019, GO:0007411=PMID:9096408, GO:0045666=GO_REF:0000019, GO:0010976=GO_REF:0000019, GO:0015630=GO_REF:0000052, GO:0005080=GO_REF:0000019, GO:0006810=GO_REF:0000037, GO:0007155=PMID:9096408} Q99689 Fasciculation and elongation protein zeta-1 protein 20111111 {GO:0005515=IPI, GO:0030424=IEA, GO:0005813=IEA, GO:0005886=IEA, GO:0043015=IEA, GO:0005874=IEA, GO:0030425=IEA, GO:0007399=TAS, GO:0051654=IEA, GO:0005737=IDA, GO:0047485=IEA, GO:0071363=IEA, GO:0007411=TAS, GO:0045666=IEA, GO:0010976=IEA, GO:0015630=IDA, GO:0005080=IEA, GO:0006810=IEA, GO:0007155=TAS} axon guidance, cell adhesion, cellular response to growth factor stimulus, establishment of mitochondrion localization, nervous system development, positive regulation of neuron differentiation, positive regulation of neuron projection development, transport axon, centrosome, cytoplasm, dendrite, microtubule, microtubule cytoskeleton, plasma membrane gamma-tubulin binding, protein N-terminus binding, protein binding, protein kinase C binding Human FEZ2 IntAct UniProtKB {GO:0005515=PMID:14690447, GO:0007165=PMID:9096408, GO:0007411=PMID:9096408, GO:0007399=PMID:9096408} Q9UHY8 Fasciculation and elongation protein zeta-2 protein 20130415 {GO:0005515=IPI, GO:0007165=TAS, GO:0007411=TAS, GO:0007399=TAS} axon guidance, nervous system development, signal transduction protein binding Human UniProtKB:Q96PY6 FEZF1 ENSEMBL UniProtKB {GO:0008285=GO_REF:0000019, GO:0021772=GO_REF:0000019, GO:0045666=GO_REF:0000019, GO:0021797=GO_REF:0000019, GO:0007411=GO_REF:0000019, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0000122=GO_REF:0000019, GO:0045893=GO_REF:0000019, GO:0001764=GO_REF:0000019, GO:0000978=GO_REF:0000019, GO:0006351=GO_REF:0000037} C9J0C5 Fez family zinc finger protein 1 protein 20130413 {GO:0008285=IEA, GO:0021772=IEA, GO:0045666=IEA, GO:0021797=IEA, GO:0007411=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0000122=IEA, GO:0045893=IEA, GO:0001764=IEA, GO:0000978=IEA, GO:0006351=IEA} axon guidance, forebrain anterior/posterior pattern specification, negative regulation of cell proliferation, negative regulation of transcription from RNA polymerase II promoter, neuron migration, olfactory bulb development, positive regulation of neuron differentiation, positive regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus RNA polymerase II core promoter proximal region sequence-specific DNA binding, zinc ion binding Human Ensembl:ENSMUSP00000031709 FFAR1 Reactome UniProtKB {GO:0005085=Reactome:REACT_19346, GO:0006112=Reactome:REACT_1505, GO:0050796=Reactome:REACT_18325, GO:0005886=Reactome:REACT_22436, GO:0007186=PMID:9344866, GO:0005887=PMID:9344866, GO:0004930=GO_REF:0000037, GO:0044281=Reactome:REACT_111217, GO:0042593=GO_REF:0000019, GO:0030073=GO_REF:0000019, GO:0008289=GO_REF:0000037} O14842 Free fatty acid receptor 1 protein 20130213 {GO:0005085=TAS, GO:0006112=TAS, GO:0050796=TAS, GO:0005886=TAS, GO:0007186=TAS, GO:0005887=TAS, GO:0004930=IEA, GO:0044281=TAS, GO:0042593=IEA, GO:0030073=IEA, GO:0008289=IEA} G-protein coupled receptor signaling pathway, energy reserve metabolic process, glucose homeostasis, insulin secretion, regulation of insulin secretion, small molecule metabolic process integral to plasma membrane, plasma membrane G-protein coupled receptor activity, guanyl-nucleotide exchange factor activity, lipid binding Human FFAR2 Reactome UniProtKB {GO:0005886=Reactome:REACT_22436, GO:0007186=PMID:9344866, GO:0005887=PMID:9344866, GO:0004930=GO_REF:0000037, GO:0008289=GO_REF:0000037} O15552 Free fatty acid receptor 2 protein 20091021 {GO:0005886=TAS, GO:0007186=TAS, GO:0005887=TAS, GO:0004930=IEA, GO:0008289=IEA} G-protein coupled receptor signaling pathway integral to plasma membrane, plasma membrane G-protein coupled receptor activity, lipid binding Human FFAR3 Reactome UniProtKB {GO:0005886=Reactome:REACT_22436, GO:0007186=PMID:9344866, GO:0005887=PMID:9344866, GO:0004930=GO_REF:0000037, GO:0008289=GO_REF:0000037} O14843 Free fatty acid receptor 3 protein 20091021 {GO:0005886=TAS, GO:0007186=TAS, GO:0005887=TAS, GO:0004930=IEA, GO:0008289=IEA} G-protein coupled receptor signaling pathway integral to plasma membrane, plasma membrane G-protein coupled receptor activity, lipid binding Human FGA BHF-UCL UniProtKB {GO:0005515=PMID:10954706, GO:0051258=GO_REF:0000002, GO:0043499=PMID:6777381, GO:0005886=Reactome:REACT_726, GO:0005102=GO_REF:0000002, GO:0005577=GO_REF:0000002, GO:0030168=Reactome:REACT_798, GO:0005576=Reactome:REACT_75905, GO:0005615=PMID:6777381, GO:0051592=PMID:6777381, GO:0007165=GO_REF:0000002, GO:0007596=Reactome:REACT_2051, GO:0002576=Reactome:REACT_318, GO:0031091=PMID:6777381, GO:0031093=Reactome:REACT_21351, GO:0030674=GO_REF:0000002, GO:0005938=GO_REF:0000019, GO:0009897=PMID:6777381} P02671 Fibrinogen alpha chain protein 20081001 {GO:0005515=IPI, GO:0051258=IEA, GO:0043499=IDA, GO:0005886=TAS, GO:0005102=IEA, GO:0005577=IEA, GO:0030168=TAS, GO:0005576=TAS, GO:0005615=IDA, GO:0051592=IDA, GO:0007165=IEA, GO:0007596=TAS, GO:0002576=TAS, GO:0031091=IDA, GO:0031093=TAS, GO:0030674=IEA, GO:0005938=IEA, GO:0009897=IDA} blood coagulation, platelet activation, platelet degranulation, protein polymerization, response to calcium ion, signal transduction cell cortex, external side of plasma membrane, extracellular region, extracellular space, fibrinogen complex, plasma membrane, platelet alpha granule, platelet alpha granule lumen eukaryotic cell surface binding, protein binding, protein binding, bridging, receptor binding Human FGB BHF-UCL UniProtKB {GO:0051258=GO_REF:0000002, GO:0043499=PMID:6777381, GO:0005886=Reactome:REACT_726, GO:0051087=PMID:19996109, GO:0005102=GO_REF:0000002, GO:0005577=GO_REF:0000002, GO:0030168=Reactome:REACT_798, GO:0072562=GO_REF:0000019, GO:0005576=Reactome:REACT_23931, GO:0005615=PMID:6777381, GO:0051592=PMID:6777381, GO:0007165=GO_REF:0000002, GO:0007596=Reactome:REACT_2051, GO:0002576=Reactome:REACT_318, GO:0031091=PMID:6777381, GO:0031093=Reactome:REACT_21351, GO:0030674=GO_REF:0000002, GO:0005938=GO_REF:0000019, GO:0009897=PMID:6777381} P02675 Fibrinogen beta chain protein 20081001 {GO:0051258=IEA, GO:0043499=IDA, GO:0005886=TAS, GO:0051087=IPI, GO:0005102=IEA, GO:0005577=IEA, GO:0030168=TAS, GO:0072562=IEA, GO:0005576=TAS, GO:0005615=IDA, GO:0051592=IDA, GO:0007165=IEA, GO:0007596=TAS, GO:0002576=TAS, GO:0031091=IDA, GO:0031093=TAS, GO:0030674=IEA, GO:0005938=IEA, GO:0009897=IDA} blood coagulation, platelet activation, platelet degranulation, protein polymerization, response to calcium ion, signal transduction blood microparticle, cell cortex, external side of plasma membrane, extracellular region, extracellular space, fibrinogen complex, plasma membrane, platelet alpha granule, platelet alpha granule lumen chaperone binding, eukaryotic cell surface binding, protein binding, bridging, receptor binding Human FGD1 HPA UniProtKB {GO:0030036=PMID:8969170, GO:0005886=GO_REF:0000052, GO:0031267=PMID:8969170, GO:0007264=Reactome:REACT_11044, GO:0008360=GO_REF:0000024, GO:0005634=GO_REF:0000052, GO:0046872=GO_REF:0000037, GO:0005829=Reactome:REACT_19216, GO:0005085=PMID:8969170, GO:0005737=GO_REF:0000052, GO:0005543=GO_REF:0000002, GO:0007010=GO_REF:0000024, GO:0009887=PMID:7954831, GO:0046847=PMID:8969170, GO:0005856=GO_REF:0000039, GO:0005089=GO_REF:0000002, GO:0051056=Reactome:REACT_11051, GO:0048011=Reactome:REACT_13776, GO:0005794=GO_REF:0000024, GO:0006915=Reactome:REACT_13638, GO:0007275=PMID:8969170, GO:0001726=GO_REF:0000024, GO:0097190=Reactome:REACT_13720, GO:0030027=GO_REF:0000024, GO:0043088=PMID:8969170, GO:0007165=PMID:8969170} P98174 FYVE, RhoGEF and PH domain-containing protein 1 protein 20100326 {GO:0030036=IDA, GO:0005886=IDA, GO:0031267=IDA, GO:0007264=TAS, GO:0008360=ISS, GO:0005634=IDA, GO:0046872=IEA, GO:0005829=TAS, GO:0005085=IDA, GO:0005737=IDA, GO:0005543=IEA, GO:0007010=ISS, GO:0009887=TAS, GO:0046847=IDA, GO:0005856=IEA, GO:0005089=IEA, GO:0051056=TAS, GO:0048011=TAS, GO:0005794=ISS, GO:0006915=TAS, GO:0007275=TAS, GO:0001726=ISS, GO:0097190=TAS, GO:0030027=ISS, GO:0043088=IDA, GO:0007165=TAS} actin cytoskeleton organization, apoptotic process, apoptotic signaling pathway, cytoskeleton organization, filopodium assembly, multicellular organismal development, neurotrophin TRK receptor signaling pathway, organ morphogenesis, regulation of Cdc42 GTPase activity, regulation of cell shape, regulation of small GTPase mediated signal transduction, signal transduction, small GTPase mediated signal transduction Golgi apparatus, cytoplasm, cytoskeleton, cytosol, lamellipodium, nucleus, plasma membrane, ruffle Rho guanyl-nucleotide exchange factor activity, guanyl-nucleotide exchange factor activity, metal ion binding, phospholipid binding, small GTPase binding Human FGD2 Reactome UniProtKB {GO:0051056=Reactome:REACT_11051, GO:0048011=Reactome:REACT_13776, GO:0005794=GO_REF:0000024, GO:0030036=GO_REF:0000024, GO:0031267=GO_REF:0000024, GO:0007264=Reactome:REACT_11044, GO:0008360=GO_REF:0000024, GO:0006915=Reactome:REACT_13638, GO:0005634=GO_REF:0000039, GO:0032587=GO_REF:0000039, GO:0097190=Reactome:REACT_13720, GO:0001726=GO_REF:0000024, GO:0046872=GO_REF:0000037, GO:0030027=GO_REF:0000024, GO:0005829=Reactome:REACT_19216, GO:0043088=GO_REF:0000024, GO:0005085=GO_REF:0000024, GO:0005737=GO_REF:0000024, GO:0005543=GO_REF:0000002, GO:0031901=GO_REF:0000039, GO:0007010=GO_REF:0000024, GO:0046847=GO_REF:0000024, GO:0005089=GO_REF:0000002, GO:0005856=GO_REF:0000039} Q7Z6J4 FYVE, RhoGEF and PH domain-containing protein 2 protein 20130301 {GO:0051056=TAS, GO:0048011=TAS, GO:0005794=ISS, GO:0030036=ISS, GO:0031267=ISS, GO:0007264=TAS, GO:0008360=ISS, GO:0006915=TAS, GO:0005634=IEA, GO:0032587=IEA, GO:0097190=TAS, GO:0001726=ISS, GO:0046872=IEA, GO:0030027=ISS, GO:0005829=TAS, GO:0043088=ISS, GO:0005085=ISS, GO:0005737=ISS, GO:0005543=IEA, GO:0031901=IEA, GO:0007010=ISS, GO:0046847=ISS, GO:0005089=IEA, GO:0005856=IEA} actin cytoskeleton organization, apoptotic process, apoptotic signaling pathway, cytoskeleton organization, filopodium assembly, neurotrophin TRK receptor signaling pathway, regulation of Cdc42 GTPase activity, regulation of cell shape, regulation of small GTPase mediated signal transduction, small GTPase mediated signal transduction Golgi apparatus, cytoplasm, cytoskeleton, cytosol, early endosome membrane, lamellipodium, nucleus, ruffle, ruffle membrane Rho guanyl-nucleotide exchange factor activity, guanyl-nucleotide exchange factor activity, metal ion binding, phospholipid binding, small GTPase binding Human FGD3 Reactome UniProtKB {GO:0051056=Reactome:REACT_11051, GO:0048011=Reactome:REACT_13776, GO:0005794=GO_REF:0000024, GO:0030036=GO_REF:0000024, GO:0031267=GO_REF:0000024, GO:0007264=Reactome:REACT_11044, GO:0035023=GO_REF:0000002, GO:0008360=GO_REF:0000024, GO:0006915=Reactome:REACT_13638, GO:0097190=Reactome:REACT_13720, GO:0001726=GO_REF:0000024, GO:0030027=GO_REF:0000024, GO:0046872=GO_REF:0000037, GO:0005829=Reactome:REACT_19216, GO:0043088=GO_REF:0000024, GO:0005622=GO_REF:0000002, GO:0005085=GO_REF:0000024, GO:0005737=GO_REF:0000024, GO:0005543=GO_REF:0000002, GO:0007010=GO_REF:0000024, GO:0046847=GO_REF:0000024, GO:0005089=GO_REF:0000002, GO:0005856=GO_REF:0000039} Q5JSP0 FYVE, RhoGEF and PH domain-containing protein 3 protein 20130301 {GO:0051056=TAS, GO:0048011=TAS, GO:0005794=ISS, GO:0030036=ISS, GO:0031267=ISS, GO:0007264=TAS, GO:0035023=IEA, GO:0008360=ISS, GO:0006915=TAS, GO:0097190=TAS, GO:0001726=ISS, GO:0030027=ISS, GO:0046872=IEA, GO:0005829=TAS, GO:0043088=ISS, GO:0005622=IEA, GO:0005085=ISS, GO:0005737=ISS, GO:0005543=IEA, GO:0007010=ISS, GO:0046847=ISS, GO:0005089=IEA, GO:0005856=IEA} actin cytoskeleton organization, apoptotic process, apoptotic signaling pathway, cytoskeleton organization, filopodium assembly, neurotrophin TRK receptor signaling pathway, regulation of Cdc42 GTPase activity, regulation of Rho protein signal transduction, regulation of cell shape, regulation of small GTPase mediated signal transduction, small GTPase mediated signal transduction Golgi apparatus, cytoplasm, cytoskeleton, cytosol, intracellular, lamellipodium, ruffle Rho guanyl-nucleotide exchange factor activity, guanyl-nucleotide exchange factor activity, metal ion binding, phospholipid binding, small GTPase binding Human FGD4 HPA UniProtKB {GO:0030036=GO_REF:0000024, GO:0030035=GO_REF:0000019, GO:0031267=GO_REF:0000024, GO:0035023=GO_REF:0000002, GO:0007264=Reactome:REACT_11044, GO:0008360=GO_REF:0000024, GO:0030032=GO_REF:0000019, GO:0030175=GO_REF:0000039, GO:0015629=GO_REF:0000052, GO:0046872=GO_REF:0000037, GO:0005829=Reactome:REACT_19216, GO:0005622=GO_REF:0000002, GO:0005085=GO_REF:0000024, GO:0005737=GO_REF:0000024, GO:0005543=GO_REF:0000002, GO:0007010=GO_REF:0000024, GO:0046847=GO_REF:0000024, GO:0005089=GO_REF:0000002, GO:0051056=Reactome:REACT_11051, GO:0048011=Reactome:REACT_13776, GO:0005794=GO_REF:0000024, GO:0006915=Reactome:REACT_13638, GO:0003779=GO_REF:0000037, GO:0097190=Reactome:REACT_13720, GO:0001726=GO_REF:0000024, GO:0030027=GO_REF:0000024, GO:0043088=GO_REF:0000024} Q96M96 FYVE, RhoGEF and PH domain-containing protein 4 protein 20110516 {GO:0030036=ISS, GO:0030035=IEA, GO:0031267=ISS, GO:0035023=IEA, GO:0007264=TAS, GO:0008360=ISS, GO:0030032=IEA, GO:0030175=IEA, GO:0015629=IDA, GO:0046872=IEA, GO:0005829=TAS, GO:0005622=IEA, GO:0005085=ISS, GO:0005737=ISS, GO:0005543=IEA, GO:0007010=ISS, GO:0046847=ISS, GO:0005089=IEA, GO:0051056=TAS, GO:0048011=TAS, GO:0005794=ISS, GO:0006915=TAS, GO:0003779=IEA, GO:0097190=TAS, GO:0001726=ISS, GO:0030027=ISS, GO:0043088=ISS} actin cytoskeleton organization, apoptotic process, apoptotic signaling pathway, cytoskeleton organization, filopodium assembly, lamellipodium assembly, microspike assembly, neurotrophin TRK receptor signaling pathway, regulation of Cdc42 GTPase activity, regulation of Rho protein signal transduction, regulation of cell shape, regulation of small GTPase mediated signal transduction, small GTPase mediated signal transduction Golgi apparatus, actin cytoskeleton, cytoplasm, cytosol, filopodium, intracellular, lamellipodium, ruffle Rho guanyl-nucleotide exchange factor activity, actin binding, guanyl-nucleotide exchange factor activity, metal ion binding, phospholipid binding, small GTPase binding Human FGD5 UniProtKB UniProtKB {GO:0005794=GO_REF:0000024, GO:0030036=GO_REF:0000024, GO:0031267=GO_REF:0000024, GO:0035023=GO_REF:0000002, GO:0005783=GO_REF:0000039, GO:0008360=GO_REF:0000024, GO:0032587=GO_REF:0000039, GO:0001726=GO_REF:0000024, GO:0030027=GO_REF:0000024, GO:0046872=GO_REF:0000037, GO:0043088=GO_REF:0000024, GO:0005622=GO_REF:0000002, GO:0005085=GO_REF:0000024, GO:0005737=GO_REF:0000024, GO:0005543=GO_REF:0000002, GO:0007010=GO_REF:0000024, GO:0046847=GO_REF:0000024, GO:0005089=GO_REF:0000002, GO:0005856=GO_REF:0000039, GO:0005769=GO_REF:0000039} Q6ZNL6 FYVE, RhoGEF and PH domain-containing protein 5 protein 20050412 {GO:0005794=ISS, GO:0030036=ISS, GO:0031267=ISS, GO:0035023=IEA, GO:0005783=IEA, GO:0008360=ISS, GO:0032587=IEA, GO:0001726=ISS, GO:0030027=ISS, GO:0046872=IEA, GO:0043088=ISS, GO:0005622=IEA, GO:0005085=ISS, GO:0005737=ISS, GO:0005543=IEA, GO:0007010=ISS, GO:0046847=ISS, GO:0005089=IEA, GO:0005856=IEA, GO:0005769=IEA} actin cytoskeleton organization, cytoskeleton organization, filopodium assembly, regulation of Cdc42 GTPase activity, regulation of Rho protein signal transduction, regulation of cell shape Golgi apparatus, cytoplasm, cytoskeleton, early endosome, endoplasmic reticulum, intracellular, lamellipodium, ruffle, ruffle membrane Rho guanyl-nucleotide exchange factor activity, guanyl-nucleotide exchange factor activity, metal ion binding, phospholipid binding, small GTPase binding Human UniProtKB:P52734 FGD6 UniProtKB UniProtKB {GO:0005794=GO_REF:0000024, GO:0030036=GO_REF:0000024, GO:0031267=GO_REF:0000024, GO:0035023=GO_REF:0000002, GO:0008360=GO_REF:0000024, GO:0001726=GO_REF:0000024, GO:0030027=GO_REF:0000024, GO:0046872=GO_REF:0000037, GO:0043088=GO_REF:0000024, GO:0005622=GO_REF:0000002, GO:0005085=GO_REF:0000024, GO:0005737=GO_REF:0000024, GO:0005543=GO_REF:0000002, GO:0007010=GO_REF:0000024, GO:0046847=GO_REF:0000024, GO:0005089=GO_REF:0000002, GO:0005856=GO_REF:0000039} Q6ZV73 FYVE, RhoGEF and PH domain-containing protein 6 protein 20050412 {GO:0005794=ISS, GO:0030036=ISS, GO:0031267=ISS, GO:0035023=IEA, GO:0008360=ISS, GO:0001726=ISS, GO:0030027=ISS, GO:0046872=IEA, GO:0043088=ISS, GO:0005622=IEA, GO:0005085=ISS, GO:0005737=ISS, GO:0005543=IEA, GO:0007010=ISS, GO:0046847=ISS, GO:0005089=IEA, GO:0005856=IEA} actin cytoskeleton organization, cytoskeleton organization, filopodium assembly, regulation of Cdc42 GTPase activity, regulation of Rho protein signal transduction, regulation of cell shape Golgi apparatus, cytoplasm, cytoskeleton, intracellular, lamellipodium, ruffle Rho guanyl-nucleotide exchange factor activity, guanyl-nucleotide exchange factor activity, metal ion binding, phospholipid binding, small GTPase binding Human UniProtKB:P52734 FGF1 BHF-UCL UniProtKB {GO:0005515=PMID:18441324, GO:0008286=Reactome:REACT_498, GO:0008284=PMID:18187602, GO:0030324=GO_REF:0000019, GO:0001759=GO_REF:0000019, GO:0009653=PMID:1693186, GO:0005615=PMID:18400376, GO:0005829=PMID:12746488, GO:0034605=PMID:12746488, GO:0005737=GO_REF:0000019, GO:0007173=Reactome:REACT_9417, GO:0045944=PMID:19229075, GO:0051781=PMID:20145243, GO:0005938=GO_REF:0000039, GO:0008201=PMID:20145243, GO:0050679=GO_REF:0000019, GO:0010740=PMID:19229075, GO:0048011=Reactome:REACT_11061, GO:0030335=PMID:20145243, GO:0060681=PMID:11731227, GO:0048015=Reactome:REACT_12464, GO:0005730=GO_REF:0000019, GO:0005578=GO_REF:0000019, GO:0007275=PMID:10903182, GO:0005576=Reactome:REACT_147854, GO:0005104=PMID:12815063, GO:0001525=GO_REF:0000037, GO:0045766=PMID:20145243, GO:0044548=PMID:11432880, GO:0007165=PMID:3778488, GO:0008543=Reactome:REACT_9515, GO:0045087=Reactome:REACT_6802, GO:0001934=GO_REF:0000019, GO:0030544=GO_REF:0000019, GO:0072163=PMID:11731227, GO:0008083=PMID:20145243, GO:0045542=PMID:19229075} P05230 Fibroblast growth factor 1 protein 20101229 {GO:0005515=IPI, GO:0008286=TAS, GO:0008284=IGI, GO:0030324=IEA, GO:0001759=IEA, GO:0009653=TAS, GO:0005615=IDA, GO:0005829=IDA, GO:0034605=IDA, GO:0005737=IEA, GO:0007173=TAS, GO:0045944=IDA, GO:0051781=IDA, GO:0005938=IEA, GO:0008201=IDA, GO:0050679=IEA, GO:0010740=IDA, GO:0048011=TAS, GO:0030335=IDA, GO:0060681=IDA, GO:0048015=TAS, GO:0005730=IEA, GO:0005578=IEA, GO:0007275=TAS, GO:0005576=TAS, GO:0005104=IPI, GO:0001525=IEA, GO:0045766=IDA, GO:0044548=IPI, GO:0007165=NAS, GO:0008543=TAS, GO:0045087=TAS, GO:0001934=IEA, GO:0030544=IEA, GO:0072163=IDA, GO:0008083=IDA, GO:0045542=IDA} anatomical structure morphogenesis, angiogenesis, branch elongation involved in ureteric bud branching, cellular response to heat, epidermal growth factor receptor signaling pathway, fibroblast growth factor receptor signaling pathway, innate immune response, insulin receptor signaling pathway, lung development, mesonephric epithelium development, multicellular organismal development, neurotrophin TRK receptor signaling pathway, organ induction, phosphatidylinositol-mediated signaling, positive regulation of angiogenesis, positive regulation of cell division, positive regulation of cell migration, positive regulation of cell proliferation, positive regulation of cholesterol biosynthetic process, positive regulation of epithelial cell proliferation, positive regulation of intracellular protein kinase cascade, positive regulation of protein phosphorylation, positive regulation of transcription from RNA polymerase II promoter, signal transduction cell cortex, cytoplasm, cytosol, extracellular region, extracellular space, nucleolus, proteinaceous extracellular matrix Hsp70 protein binding, S100 protein binding, fibroblast growth factor receptor binding, growth factor activity, heparin binding, protein binding Human FGF10 Reactome UniProtKB {GO:0010838=PMID:17449030, GO:0051549=PMID:17449030, GO:0090263=GO_REF:0000019, GO:0005111=PMID:19224135, GO:0050731=PMID:17449030, GO:0046579=PMID:12804770, GO:0030878=GO_REF:0000019, GO:0005615=PMID:16597614, GO:0031069=GO_REF:0000019, GO:0060430=PMID:17071719, GO:0031076=GO_REF:0000019, GO:0060915=GO_REF:0000019, GO:0060436=GO_REF:0000019, GO:0045747=GO_REF:0000019, GO:0031532=PMID:17449030, GO:0009986=PMID:11923311, GO:0045740=PMID:17471512, GO:0042056=PMID:9740653, GO:0050930=GO_REF:0000019, GO:0046877=PMID:19102732, GO:0060441=GO_REF:0000019, GO:0045087=Reactome:REACT_6802, GO:0042060=PMID:11896977, GO:0060447=PMID:9740653, GO:0051145=GO_REF:0000019, GO:0060595=PMID:11923311, GO:0021983=GO_REF:0000019, GO:0005634=PMID:17471512, GO:0048146=GO_REF:0000019, GO:0045739=PMID:14975937, GO:0000187=PMID:14975937, GO:0060665=GO_REF:0000019, GO:0060664=GO_REF:0000019, GO:0060667=GO_REF:0000019, GO:0060661=GO_REF:0000019, GO:0042475=GO_REF:0000019, GO:0007431=PMID:17213838, GO:0035019=GO_REF:0000019, GO:0060054=PMID:19152659, GO:0048011=Reactome:REACT_11061, GO:0048015=Reactome:REACT_12464, GO:0001823=PMID:18437684, GO:0005576=Reactome:REACT_147854, GO:0005104=PMID:11923311, GO:0050918=PMID:9740653, GO:0032808=PMID:17213838, GO:0003338=GO_REF:0000019, GO:0048557=GO_REF:0000019, GO:0001974=GO_REF:0000019, GO:0034394=PMID:17449030, GO:0060510=GO_REF:0000019, GO:0048754=PMID:17959718, GO:0061033=PMID:10541313, GO:0001656=PMID:18437684, GO:0071157=PMID:17188682, GO:0048538=PMID:17969154, GO:0001759=GO_REF:0000019, GO:0048536=GO_REF:0000019, GO:0042693=GO_REF:0000019, GO:0009880=GO_REF:0000019, GO:0007173=Reactome:REACT_9417, GO:0030538=GO_REF:0000019, GO:0032496=GO_REF:0000019, GO:0048808=GO_REF:0000019, GO:0048807=GO_REF:0000019, GO:0070374=PMID:14975937, GO:0070371=PMID:17959718, GO:0032355=GO_REF:0000019, GO:0050679=GO_REF:0000019, GO:0060685=GO_REF:0000019, GO:0050677=PMID:11923311, GO:0048286=GO_REF:0000019, GO:0061115=GO_REF:0000019, GO:0030916=GO_REF:0000019, GO:0050671=PMID:19152659, GO:0032781=PMID:12804770, GO:0032925=GO_REF:0000019, GO:0050674=PMID:11923311, GO:0050673=PMID:19224135, GO:0045931=GO_REF:0000019, GO:0050872=GO_REF:0000019, GO:0008543=Reactome:REACT_9483, GO:0070384=GO_REF:0000019, GO:0060174=GO_REF:0000019, GO:0045893=PMID:17500053, GO:0008083=PMID:15690149, GO:0008286=Reactome:REACT_498, GO:0030949=GO_REF:0000019, GO:0007368=GO_REF:0000019, GO:0060428=PMID:9740653, GO:0008285=GO_REF:0000019, GO:0005886=PMID:16597614, GO:0060879=GO_REF:0000019, GO:0042246=GO_REF:0000019, GO:0035265=GO_REF:0000019, GO:0045944=GO_REF:0000019, GO:0071338=PMID:16086254, GO:0060496=GO_REF:0000019, GO:0008201=PMID:11923311, GO:0070352=GO_REF:0000019, GO:0070075=PMID:19102732, GO:0043066=GO_REF:0000019, GO:0001525=GO_REF:0000019, GO:0043616=GO_REF:0000019, GO:0031012=PMID:17959718, GO:0031659=PMID:17188682, GO:0031016=GO_REF:0000019, GO:0060019=GO_REF:0000024, GO:0008589=GO_REF:0000019, GO:0060615=GO_REF:0000019, GO:0010631=GO_REF:0000019, GO:0010634=PMID:17500053, GO:0043410=PMID:12804770} O15520 Fibroblast growth factor 10 protein 20130301 {GO:0010838=IDA, GO:0051549=IDA, GO:0090263=IEA, GO:0005111=IPI, GO:0050731=IDA, GO:0046579=IDA, GO:0030878=IEA, GO:0005615=IDA, GO:0031069=IEA, GO:0060430=IMP, GO:0031076=IEA, GO:0060915=IEA, GO:0060436=IEA, GO:0045747=IEA, GO:0031532=IDA, GO:0009986=NAS, GO:0045740=IMP, GO:0042056=IDA, GO:0050930=IEA, GO:0046877=IMP, GO:0060441=IEA, GO:0045087=TAS, GO:0042060=IDA, GO:0060447=IDA, GO:0051145=IEA, GO:0060595=IDA, GO:0021983=IEA, GO:0005634=IDA, GO:0048146=IEA, GO:0045739=IDA, GO:0000187=IDA, GO:0060665=IEA, GO:0060664=IEA, GO:0060667=IEA, GO:0060661=IEA, GO:0042475=IEA, GO:0007431=IMP, GO:0035019=IEA, GO:0060054=NAS, GO:0048011=TAS, GO:0048015=TAS, GO:0001823=IEP, GO:0005576=TAS, GO:0005104=IDA, GO:0050918=IDA, GO:0032808=IMP, GO:0003338=IEA, GO:0048557=IEA, GO:0001974=IEA, GO:0034394=IDA, GO:0060510=IEA, GO:0048754=IDA, GO:0061033=IDA, GO:0001656=IEP, GO:0071157=IDA, GO:0048538=IDA, GO:0001759=IEA, GO:0048536=IEA, GO:0042693=IEA, GO:0009880=IEA, GO:0007173=TAS, GO:0030538=IEA, GO:0032496=IEA, GO:0048808=IEA, GO:0048807=IEA, GO:0070374=IDA, GO:0070371=IDA, GO:0032355=IEA, GO:0050679=IEA, GO:0060685=IEA, GO:0050677=IDA, GO:0048286=IEA, GO:0061115=IEA, GO:0030916=IEA, GO:0050671=IDA, GO:0032781=IDA, GO:0032925=IEA, GO:0050674=IDA, GO:0050673=IDA, GO:0045931=IEA, GO:0050872=IEA, GO:0008543=TAS, GO:0070384=IEA, GO:0060174=IEA, GO:0045893=IDA, GO:0008083=IDA, GO:0008286=TAS, GO:0030949=IEA, GO:0007368=IEA, GO:0060428=IDA, GO:0008285=IEA, GO:0005886=IDA, GO:0060879=IEA, GO:0042246=IEA, GO:0035265=IEA, GO:0045944=IEA, GO:0071338=IDA, GO:0060496=IEA, GO:0008201=IDA, GO:0070352=IEA, GO:0070075=IMP, GO:0043066=IEA, GO:0001525=IEA, GO:0043616=IEA, GO:0031012=IDA, GO:0031659=IDA, GO:0031016=IEA, GO:0060019=ISS, GO:0008589=IEA, GO:0060615=IEA, GO:0010631=IEA, GO:0010634=IDA, GO:0043410=IDA} ERK1 and ERK2 cascade, Harderian gland development, Type II pneumocyte differentiation, actin cytoskeleton reorganization, activation of MAPK activity, angiogenesis, blood vessel remodeling, branch elongation involved in salivary gland morphogenesis, branching morphogenesis of an epithelial tube, bronchiole morphogenesis, bud outgrowth involved in lung branching, determination of left/right symmetry, embryonic camera-type eye development, embryonic digestive tract morphogenesis, embryonic genitalia morphogenesis, embryonic pattern specification, epidermal growth factor receptor signaling pathway, epithelial cell migration, epithelial cell proliferation, epithelial cell proliferation involved in salivary gland morphogenesis, epithelial tube branching involved in lung morphogenesis, female genitalia morphogenesis, fibroblast growth factor receptor signaling pathway, fibroblast growth factor receptor signaling pathway involved in mammary gland specification, hair follicle morphogenesis, induction of positive chemotaxis, innate immune response, insulin receptor signaling pathway, keratinocyte proliferation, lacrimal gland development, limb bud formation, lung alveolus development, lung epithelium development, lung proximal/distal axis specification, lung saccule development, male genitalia morphogenesis, mammary gland bud formation, mesenchymal cell differentiation involved in lung development, mesenchymal-epithelial cell signaling involved in lung development, mesonephros development, metanephros development, metanephros morphogenesis, muscle cell fate commitment, negative regulation of apoptotic process, negative regulation of cell cycle arrest, negative regulation of cell proliferation, neurotrophin TRK receptor signaling pathway, odontogenesis of dentin-containing tooth, organ growth, organ induction, otic vesicle formation, pancreas development, phosphatidylinositol-mediated signaling, pituitary gland development, positive chemotaxis, positive regulation of ATPase activity, positive regulation of DNA repair, positive regulation of DNA replication, positive regulation of ERK1 and ERK2 cascade, positive regulation of MAPK cascade, positive regulation of Notch signaling pathway, positive regulation of Ras protein signal transduction, positive regulation of canonical Wnt receptor signaling pathway, positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S, positive regulation of epithelial cell migration, positive regulation of epithelial cell proliferation, positive regulation of epithelial cell proliferation involved in wound healing, positive regulation of fibroblast proliferation, positive regulation of hair follicle cell proliferation, positive regulation of keratinocyte migration, positive regulation of keratinocyte proliferation, positive regulation of lymphocyte proliferation, positive regulation of mitotic cell cycle, positive regulation of peptidyl-tyrosine phosphorylation, positive regulation of transcription from RNA polymerase II promoter, positive regulation of transcription, DNA-dependent, positive regulation of urothelial cell proliferation, positive regulation of vascular endothelial growth factor receptor signaling pathway, positive regulation of white fat cell proliferation, protein localization to cell surface, radial glial cell differentiation, regulation of activin receptor signaling pathway, regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling, regulation of prostatic bud formation, regulation of saliva secretion, regulation of smoothened signaling pathway, response to estradiol stimulus, response to lipopolysaccharide, salivary gland development, secretion by lung epithelial cell involved in lung growth, semicircular canal fusion, smooth muscle cell differentiation, somatic stem cell maintenance, spleen development, submandibular salivary gland formation, tear secretion, thymus development, thyroid gland development, tissue regeneration, urothelial cell proliferation, white fat cell differentiation, wound healing cell surface, extracellular matrix, extracellular region, extracellular space, nucleus, plasma membrane chemoattractant activity, fibroblast growth factor receptor binding, growth factor activity, heparin binding, type 2 fibroblast growth factor receptor binding Human FGF12 PINC UniProtKB {GO:0007507=PMID:10049777, GO:0050905=GO_REF:0000019, GO:0007165=PMID:8790420, GO:0008344=GO_REF:0000019, GO:0010765=GO_REF:0000019, GO:0007267=PMID:8790420, GO:0007268=GO_REF:0000019, GO:0005634=PMID:8790420, GO:0005615=PMID:10049777, GO:2001258=GO_REF:0000019, GO:0008083=GO_REF:0000037, GO:0007399=PMID:8790420} P61328 Fibroblast growth factor 12 protein 20061127 {GO:0007507=TAS, GO:0050905=IEA, GO:0007165=TAS, GO:0008344=IEA, GO:0010765=IEA, GO:0007267=TAS, GO:0007268=IEA, GO:0005634=IDA, GO:0005615=TAS, GO:2001258=IEA, GO:0008083=IEA, GO:0007399=TAS} adult locomotory behavior, cell-cell signaling, heart development, negative regulation of cation channel activity, nervous system development, neuromuscular process, positive regulation of sodium ion transport, signal transduction, synaptic transmission extracellular space, nucleus growth factor activity Human FGF13 GOC UniProtKB {GO:0008017=GO_REF:0000024, GO:0005515=PMID:15282281, GO:0030424=GO_REF:0000024, GO:0043005=GO_REF:0000024, GO:0005886=GO_REF:0000024, GO:0007267=PMID:8790420, GO:0005634=PMID:8790420, GO:0030175=GO_REF:0000024, GO:0030425=GO_REF:0000024, GO:0048671=GO_REF:0000024, GO:0030426=GO_REF:0000024, GO:0005737=PMID:12244047, GO:0021795=GO_REF:0000024, GO:0014704=GO_REF:0000024, GO:0000165=PMID:12244047, GO:0045860=PMID:12244047, GO:0007613=GO_REF:0000024, GO:0007612=GO_REF:0000024, GO:0005874=GO_REF:0000024, GO:0048487=GO_REF:0000024, GO:0005730=GO_REF:0000039, GO:0030295=PMID:12244047, GO:0045200=GO_REF:0000024, GO:0072659=GO_REF:0000024, GO:0007399=PMID:8790420, GO:0044325=GO_REF:0000024, GO:0007165=PMID:8790420, GO:0021766=GO_REF:0000024, GO:0046785=GO_REF:0000024, GO:0007026=GO_REF:0000024, GO:0001764=GO_REF:0000024, GO:0008083=GO_REF:0000002, GO:0017080=PMID:15282281} Q92913 Fibroblast growth factor 13 protein 20130413 {GO:0008017=ISS, GO:0005515=IPI, GO:0030424=ISS, GO:0043005=ISS, GO:0005886=ISS, GO:0007267=TAS, GO:0005634=IDA, GO:0030175=ISS, GO:0030425=ISS, GO:0048671=ISS, GO:0030426=ISS, GO:0005737=IPI, GO:0021795=ISS, GO:0014704=ISS, GO:0000165=IDA, GO:0045860=IGI, GO:0007613=ISS, GO:0007612=ISS, GO:0005874=ISS, GO:0048487=ISS, GO:0005730=IEA, GO:0030295=IGI, GO:0045200=ISS, GO:0072659=ISS, GO:0007399=TAS, GO:0044325=ISS, GO:0007165=TAS, GO:0021766=ISS, GO:0046785=ISS, GO:0007026=ISS, GO:0001764=ISS, GO:0008083=IEA, GO:0017080=IDA} MAPK cascade, cell-cell signaling, cerebral cortex cell migration, establishment of neuroblast polarity, hippocampus development, learning, memory, microtubule polymerization, negative regulation of collateral sprouting, negative regulation of microtubule depolymerization, nervous system development, neuron migration, positive regulation of protein kinase activity, protein localization to plasma membrane, signal transduction axon, cytoplasm, dendrite, filopodium, growth cone, intercalated disc, microtubule, neuron projection, nucleolus, nucleus, plasma membrane beta-tubulin binding, growth factor activity, ion channel binding, microtubule binding, protein binding, protein kinase activator activity, sodium channel regulator activity Human UniProtKB:Q13387-2 FGF16 Reactome UniProtKB {GO:0008286=Reactome:REACT_498, GO:0048011=Reactome:REACT_11061, GO:0048015=Reactome:REACT_12464, GO:0007267=PMID:9473496, GO:0005576=Reactome:REACT_121127, GO:0005615=PMID:9473496, GO:0009266=PMID:9473496, GO:0007165=PMID:9473496, GO:0007173=Reactome:REACT_9417, GO:0008543=Reactome:REACT_9510, GO:0045087=Reactome:REACT_6802, GO:0008152=PMID:9473496, GO:0009887=PMID:9473496, GO:0008083=GO_REF:0000037} O43320 Fibroblast growth factor 16 protein 20110530 {GO:0008286=TAS, GO:0048011=TAS, GO:0048015=TAS, GO:0007267=TAS, GO:0005576=TAS, GO:0005615=TAS, GO:0009266=TAS, GO:0007165=TAS, GO:0007173=TAS, GO:0008543=TAS, GO:0045087=TAS, GO:0008152=TAS, GO:0009887=TAS, GO:0008083=IEA} cell-cell signaling, epidermal growth factor receptor signaling pathway, fibroblast growth factor receptor signaling pathway, innate immune response, insulin receptor signaling pathway, metabolic process, neurotrophin TRK receptor signaling pathway, organ morphogenesis, phosphatidylinositol-mediated signaling, response to temperature stimulus, signal transduction extracellular region, extracellular space growth factor activity Human FGF17 Reactome UniProtKB {GO:0008286=Reactome:REACT_498, GO:0048011=Reactome:REACT_11061, GO:0008284=GO_REF:0000019, GO:0048015=Reactome:REACT_12464, GO:0005111=PMID:16384934, GO:0007267=PMID:9514906, GO:0005576=Reactome:REACT_147854, GO:0005105=PMID:16384934, GO:0005615=PMID:9514906, GO:0007399=PMID:9514906, GO:0007165=PMID:9514906, GO:0007173=Reactome:REACT_9417, GO:0008543=Reactome:REACT_9515, GO:0045087=Reactome:REACT_6802, GO:0008083=GO_REF:0000037} O60258 Fibroblast growth factor 17 protein 20130301 {GO:0008286=TAS, GO:0048011=TAS, GO:0008284=IEA, GO:0048015=TAS, GO:0005111=IDA, GO:0007267=TAS, GO:0005576=TAS, GO:0005105=IDA, GO:0005615=TAS, GO:0007399=TAS, GO:0007165=TAS, GO:0007173=TAS, GO:0008543=TAS, GO:0045087=TAS, GO:0008083=IEA} cell-cell signaling, epidermal growth factor receptor signaling pathway, fibroblast growth factor receptor signaling pathway, innate immune response, insulin receptor signaling pathway, nervous system development, neurotrophin TRK receptor signaling pathway, phosphatidylinositol-mediated signaling, positive regulation of cell proliferation, signal transduction extracellular region, extracellular space growth factor activity, type 1 fibroblast growth factor receptor binding, type 2 fibroblast growth factor receptor binding Human FGF18 LIFEdb UniProtKB {GO:0008286=Reactome:REACT_498, GO:0030949=GO_REF:0000019, GO:0008284=GO_REF:0000019, GO:0030324=GO_REF:0000019, GO:0005111=PMID:16384934, GO:0007267=PMID:9742123, GO:0009653=PMID:9742123, GO:0005615=PMID:9742123, GO:0002063=GO_REF:0000019, GO:0007173=Reactome:REACT_9417, GO:0032332=GO_REF:0000019, GO:0070374=GO_REF:0000019, GO:0048011=Reactome:REACT_11061, GO:0048015=Reactome:REACT_12464, GO:0005730=GO_REF:0000054, GO:0005576=Reactome:REACT_147854, GO:0005105=PMID:16384934, GO:0001525=GO_REF:0000019, GO:0007399=GO_REF:0000019, GO:0007165=PMID:9742123, GO:0001958=GO_REF:0000019, GO:0001957=GO_REF:0000019, GO:0008543=Reactome:REACT_9510, GO:0045087=Reactome:REACT_6802, GO:0008083=GO_REF:0000037} O76093 Fibroblast growth factor 18 protein 20100607 {GO:0008286=TAS, GO:0030949=IEA, GO:0008284=IEA, GO:0030324=IEA, GO:0005111=IDA, GO:0007267=TAS, GO:0009653=TAS, GO:0005615=TAS, GO:0002063=IEA, GO:0007173=TAS, GO:0032332=IEA, GO:0070374=IEA, GO:0048011=TAS, GO:0048015=TAS, GO:0005730=IDA, GO:0005576=TAS, GO:0005105=IDA, GO:0001525=IEA, GO:0007399=IEA, GO:0007165=TAS, GO:0001958=IEA, GO:0001957=IEA, GO:0008543=TAS, GO:0045087=TAS, GO:0008083=IEA} anatomical structure morphogenesis, angiogenesis, cell-cell signaling, chondrocyte development, endochondral ossification, epidermal growth factor receptor signaling pathway, fibroblast growth factor receptor signaling pathway, innate immune response, insulin receptor signaling pathway, intramembranous ossification, lung development, nervous system development, neurotrophin TRK receptor signaling pathway, phosphatidylinositol-mediated signaling, positive regulation of ERK1 and ERK2 cascade, positive regulation of cell proliferation, positive regulation of chondrocyte differentiation, positive regulation of vascular endothelial growth factor receptor signaling pathway, signal transduction extracellular region, extracellular space, nucleolus growth factor activity, type 1 fibroblast growth factor receptor binding, type 2 fibroblast growth factor receptor binding Human FGF19 Reactome UniProtKB {GO:0008286=Reactome:REACT_498, GO:0005515=PMID:18829467, GO:0048011=Reactome:REACT_11061, GO:0008284=PMID:18187602, GO:0048015=Reactome:REACT_12464, GO:0001755=GO_REF:0000019, GO:0046330=PMID:12815072, GO:0005104=PMID:10525310, GO:0005576=Reactome:REACT_147854, GO:0070858=PMID:12815072, GO:0007399=PMID:9931477, GO:0007507=GO_REF:0000019, GO:0007173=Reactome:REACT_9417, GO:0008543=Reactome:REACT_9470, GO:0045087=Reactome:REACT_6802, GO:0046326=PMID:17623664, GO:0070374=PMID:17623664, GO:0008083=GO_REF:0000037} O95750 Fibroblast growth factor 19 protein 20130301 {GO:0008286=TAS, GO:0005515=IPI, GO:0048011=TAS, GO:0008284=IGI, GO:0048015=TAS, GO:0001755=IEA, GO:0046330=IDA, GO:0005104=IPI, GO:0005576=TAS, GO:0070858=IDA, GO:0007399=TAS, GO:0007507=IEA, GO:0007173=TAS, GO:0008543=TAS, GO:0045087=TAS, GO:0046326=IDA, GO:0070374=IDA, GO:0008083=IEA} epidermal growth factor receptor signaling pathway, fibroblast growth factor receptor signaling pathway, heart development, innate immune response, insulin receptor signaling pathway, negative regulation of bile acid biosynthetic process, nervous system development, neural crest cell migration, neurotrophin TRK receptor signaling pathway, phosphatidylinositol-mediated signaling, positive regulation of ERK1 and ERK2 cascade, positive regulation of JNK cascade, positive regulation of cell proliferation, positive regulation of glucose import extracellular region fibroblast growth factor receptor binding, growth factor activity, protein binding Human FGF2 GOC UniProtKB {GO:0060045=PMID:9553078, GO:0005515=PMID:18329368, GO:0030308=GO_REF:0000019, GO:0001658=PMID:12631064, GO:0001759=GO_REF:0000019, GO:0048598=PMID:20011604, GO:0048678=GO_REF:0000019, GO:0005615=GO_REF:0000019, GO:0060644=GO_REF:0000019, GO:0043552=PMID:20011604, GO:0010764=PMID:19577615, GO:0006935=PMID:10848592, GO:0007173=Reactome:REACT_9417, GO:0032958=PMID:20011604, GO:0061045=PMID:19577615, GO:0060548=PMID:12631064, GO:0009887=PMID:10903182, GO:0051781=GO_REF:0000037, GO:0070374=PMID:17167778, GO:0051209=PMID:20011604, GO:0017134=GO_REF:0000019, GO:0043536=PMID:18555217, GO:0008543=Reactome:REACT_9515, GO:0045087=Reactome:REACT_6802, GO:0042060=PMID:20011604, GO:0006700=GO_REF:0000019, GO:0010001=GO_REF:0000019, GO:0045893=PMID:17500071, GO:0045892=GO_REF:0000019, GO:0043537=PMID:18555217, GO:0008286=Reactome:REACT_498, GO:0008284=PMID:8663044, GO:0008285=GO_REF:0000019, GO:0060591=PMID:17167778, GO:0030324=GO_REF:0000019, GO:0002042=PMID:19351956, GO:0021940=GO_REF:0000019, GO:0042660=PMID:18635606, GO:0007265=PMID:10848592, GO:0060129=GO_REF:0000019, GO:0005634=GO_REF:0000039, GO:0048864=GO_REF:0000019, GO:0060128=GO_REF:0000019, GO:0005829=GO_REF:0000019, GO:0000187=PMID:9712850, GO:0000186=GO_REF:0000019, GO:0030374=PMID:17500071, GO:0051726=GO_REF:0000019, GO:0008201=GO_REF:0000037, GO:0048011=Reactome:REACT_11061, GO:0006661=PMID:20011604, GO:0048015=Reactome:REACT_12464, GO:0006915=GO_REF:0000019, GO:0045765=PMID:20011604, GO:0005576=Reactome:REACT_147854, GO:0005104=PMID:10830168, GO:0000189=GO_REF:0000019, GO:0045766=PMID:20011604, GO:0050918=PMID:18059339, GO:0007399=PMID:9576942, GO:0010863=PMID:20011604, GO:0045669=GO_REF:0000019, GO:0007165=PMID:9712850, GO:0021762=GO_REF:0000019, GO:0030214=PMID:19577615, GO:0046668=GO_REF:0000019} P09038 Fibroblast growth factor 2 protein 20130413 {GO:0060045=IDA, GO:0005515=IPI, GO:0030308=IEA, GO:0001658=IDA, GO:0001759=IEA, GO:0048598=TAS, GO:0048678=IEA, GO:0005615=IEA, GO:0060644=IEA, GO:0043552=IDA, GO:0010764=IDA, GO:0006935=TAS, GO:0007173=TAS, GO:0032958=IDA, GO:0061045=IDA, GO:0060548=IDA, GO:0009887=TAS, GO:0051781=IEA, GO:0070374=IDA, GO:0051209=IDA, GO:0017134=IEA, GO:0043536=IDA, GO:0008543=TAS, GO:0045087=TAS, GO:0042060=TAS, GO:0006700=IEA, GO:0010001=IEA, GO:0045893=IDA, GO:0045892=IEA, GO:0043537=IDA, GO:0008286=TAS, GO:0008284=IGI, GO:0008285=IEA, GO:0060591=IDA, GO:0030324=IEA, GO:0002042=IGI, GO:0021940=IEA, GO:0042660=IDA, GO:0007265=TAS, GO:0060129=IEA, GO:0005634=IEA, GO:0048864=IEA, GO:0060128=IEA, GO:0005829=IEA, GO:0000187=TAS, GO:0000186=IEA, GO:0030374=IDA, GO:0051726=IEA, GO:0008201=IEA, GO:0048011=TAS, GO:0006661=IDA, GO:0048015=TAS, GO:0006915=IEA, GO:0045765=TAS, GO:0005576=TAS, GO:0005104=IPI, GO:0000189=IEA, GO:0045766=IDA, GO:0050918=IDA, GO:0007399=TAS, GO:0010863=IDA, GO:0045669=IEA, GO:0007165=NAS, GO:0021762=IEA, GO:0030214=IDA, GO:0046668=IEA} C21-steroid hormone biosynthetic process, MAPK import into nucleus, Ras protein signal transduction, activation of MAPK activity, activation of MAPKK activity, apoptotic process, branching involved in ureteric bud morphogenesis, cell migration involved in sprouting angiogenesis, chemotaxis, chondroblast differentiation, corticotropin hormone secreting cell differentiation, embryonic morphogenesis, epidermal growth factor receptor signaling pathway, fibroblast growth factor receptor signaling pathway, glial cell differentiation, hyaluronan catabolic process, innate immune response, inositol phosphate biosynthetic process, insulin receptor signaling pathway, lung development, mammary gland epithelial cell differentiation, negative regulation of blood vessel endothelial cell migration, negative regulation of cell death, negative regulation of cell growth, negative regulation of cell proliferation, negative regulation of fibroblast migration, negative regulation of transcription, DNA-dependent, negative regulation of wound healing, nervous system development, neurotrophin TRK receptor signaling pathway, organ induction, organ morphogenesis, phosphatidylinositol biosynthetic process, phosphatidylinositol-mediated signaling, positive chemotaxis, positive regulation of ERK1 and ERK2 cascade, positive regulation of angiogenesis, positive regulation of blood vessel endothelial cell migration, positive regulation of cardiac muscle cell proliferation, positive regulation of cell division, positive regulation of cell fate specification, positive regulation of cell proliferation, positive regulation of cerebellar granule cell precursor proliferation, positive regulation of osteoblast differentiation, positive regulation of phosphatidylinositol 3-kinase activity, positive regulation of phospholipase C activity, positive regulation of transcription, DNA-dependent, regulation of angiogenesis, regulation of cell cycle, regulation of retinal cell programmed cell death, release of sequestered calcium ion into cytosol, response to axon injury, signal transduction, stem cell development, substantia nigra development, thyroid-stimulating hormone-secreting cell differentiation, wound healing cytosol, extracellular region, extracellular space, nucleus fibroblast growth factor binding, fibroblast growth factor receptor binding, heparin binding, ligand-dependent nuclear receptor transcription coactivator activity, protein binding Human FGF20 Reactome UniProtKB {GO:0008286=Reactome:REACT_498, GO:0048011=Reactome:REACT_11061, GO:0008284=GO_REF:0000019, GO:0060113=GO_REF:0000019, GO:0048015=Reactome:REACT_12464, GO:0060043=GO_REF:0000019, GO:0007267=PMID:10913340, GO:0005104=GO_REF:0000019, GO:0005576=Reactome:REACT_120860, GO:0007165=PMID:10913340, GO:0007173=Reactome:REACT_9417, GO:0008543=Reactome:REACT_9515, GO:0045087=Reactome:REACT_6802, GO:0070374=GO_REF:0000019, GO:0008083=GO_REF:0000019} Q9NP95 Fibroblast growth factor 20 protein 20110530 {GO:0008286=TAS, GO:0048011=TAS, GO:0008284=IEA, GO:0060113=IEA, GO:0048015=TAS, GO:0060043=IEA, GO:0007267=TAS, GO:0005104=IEA, GO:0005576=TAS, GO:0007165=TAS, GO:0007173=TAS, GO:0008543=TAS, GO:0045087=TAS, GO:0070374=IEA, GO:0008083=IEA} cell-cell signaling, epidermal growth factor receptor signaling pathway, fibroblast growth factor receptor signaling pathway, innate immune response, inner ear receptor cell differentiation, insulin receptor signaling pathway, neurotrophin TRK receptor signaling pathway, phosphatidylinositol-mediated signaling, positive regulation of ERK1 and ERK2 cascade, positive regulation of cell proliferation, regulation of cardiac muscle cell proliferation, signal transduction extracellular region fibroblast growth factor receptor binding, growth factor activity Human FGF21 BHF-UCL UniProtKB {GO:0005515=PMID:19117008, GO:0007165=PMID:10858549, GO:0046326=PMID:17623664, GO:0007267=PMID:10858549, GO:0010988=PMID:22378787, GO:0005576=GO_REF:0000039, GO:0005104=GO_REF:0000002, GO:0045716=PMID:22378787, GO:0070374=PMID:17623664, GO:0008083=GO_REF:0000037} Q9NSA1 Fibroblast growth factor 21 protein 20120601 {GO:0005515=IPI, GO:0007165=TAS, GO:0046326=IDA, GO:0007267=TAS, GO:0010988=NAS, GO:0005576=IEA, GO:0005104=IEA, GO:0045716=NAS, GO:0070374=IDA, GO:0008083=IEA} cell-cell signaling, positive regulation of ERK1 and ERK2 cascade, positive regulation of glucose import, positive regulation of low-density lipoprotein particle receptor biosynthetic process, regulation of low-density lipoprotein particle clearance, signal transduction extracellular region fibroblast growth factor receptor binding, growth factor activity, protein binding Human FGF22 Reactome UniProtKB {GO:0008286=Reactome:REACT_498, GO:0048011=Reactome:REACT_11061, GO:0005794=GO_REF:0000019, GO:0009986=GO_REF:0000019, GO:0048015=Reactome:REACT_12464, GO:0005730=GO_REF:0000019, GO:0005576=Reactome:REACT_111238, GO:0005615=PMID:11342227, GO:0030154=PMID:11342227, GO:0007173=Reactome:REACT_9417, GO:0008543=Reactome:REACT_9483, GO:0045087=Reactome:REACT_6802, GO:0008083=GO_REF:0000037} Q9HCT0 Fibroblast growth factor 22 protein 20110530 {GO:0008286=TAS, GO:0048011=TAS, GO:0005794=IEA, GO:0009986=IEA, GO:0048015=TAS, GO:0005730=IEA, GO:0005576=TAS, GO:0005615=NAS, GO:0030154=NAS, GO:0007173=TAS, GO:0008543=TAS, GO:0045087=TAS, GO:0008083=IEA} cell differentiation, epidermal growth factor receptor signaling pathway, fibroblast growth factor receptor signaling pathway, innate immune response, insulin receptor signaling pathway, neurotrophin TRK receptor signaling pathway, phosphatidylinositol-mediated signaling Golgi apparatus, cell surface, extracellular region, extracellular space, nucleolus growth factor activity Human FGF23 BHF-UCL UniProtKB {GO:0008286=Reactome:REACT_498, GO:0048011=Reactome:REACT_11061, GO:0048015=Reactome:REACT_12464, GO:0042369=PMID:15040831, GO:0055062=PMID:11062477, GO:0005576=Reactome:REACT_120860, GO:0005105=GO_REF:0000019, GO:0006796=GO_REF:0000019, GO:0030502=PMID:18282132, GO:0005615=PMID:22261194, GO:0030154=GO_REF:0000029, GO:0046888=GO_REF:0000024, GO:0010980=PMID:15040831, GO:0045668=PMID:18282132, GO:0007173=Reactome:REACT_9417, GO:0008543=Reactome:REACT_9515, GO:0030643=GO_REF:0000019, GO:0045087=Reactome:REACT_6802, GO:0070374=GO_REF:0000019, GO:0045893=GO_REF:0000019, GO:0008083=GO_REF:0000037, GO:0090080=GO_REF:0000019, GO:0010966=PMID:11409890} Q9GZV9 Fibroblast growth factor 23 protein 20120228 {GO:0008286=TAS, GO:0048011=TAS, GO:0048015=TAS, GO:0042369=IDA, GO:0055062=IMP, GO:0005576=TAS, GO:0005105=IEA, GO:0006796=IEA, GO:0030502=IDA, GO:0005615=ISS, GO:0030154=NAS, GO:0046888=ISS, GO:0010980=IDA, GO:0045668=IDA, GO:0007173=TAS, GO:0008543=TAS, GO:0030643=IEA, GO:0045087=TAS, GO:0070374=IEA, GO:0045893=IEA, GO:0008083=IEA, GO:0090080=IEA, GO:0010966=IDA} cell differentiation, cellular phosphate ion homeostasis, epidermal growth factor receptor signaling pathway, fibroblast growth factor receptor signaling pathway, innate immune response, insulin receptor signaling pathway, negative regulation of bone mineralization, negative regulation of hormone secretion, negative regulation of osteoblast differentiation, neurotrophin TRK receptor signaling pathway, phosphate ion homeostasis, phosphate-containing compound metabolic process, phosphatidylinositol-mediated signaling, positive regulation of ERK1 and ERK2 cascade, positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway, positive regulation of transcription, DNA-dependent, positive regulation of vitamin D 24-hydroxylase activity, regulation of phosphate transport, vitamin D catabolic process extracellular region, extracellular space growth factor activity, type 1 fibroblast growth factor receptor binding Human UniProtKB:F1SKZ1 FGF3 BHF-UCL UniProtKB {GO:0008286=Reactome:REACT_498, GO:0005515=PMID:16263090, GO:0048011=Reactome:REACT_11061, GO:0008284=PMID:8663044, GO:0005794=GO_REF:0000019, GO:0048015=Reactome:REACT_12464, GO:0030916=GO_REF:0000019, GO:0007267=PMID:2470007, GO:0005576=Reactome:REACT_147854, GO:0048538=GO_REF:0000019, GO:0001759=GO_REF:0000019, GO:0048752=GO_REF:0000019, GO:0009653=PMID:2470007, GO:0036342=GO_REF:0000019, GO:0007165=PMID:2470007, GO:0007173=Reactome:REACT_9417, GO:0008543=Reactome:REACT_9483, GO:0045087=Reactome:REACT_6802, GO:0051781=GO_REF:0000037, GO:0008083=GO_REF:0000037, GO:0055026=PMID:20702560} P11487 Fibroblast growth factor 3 protein 20110418 {GO:0008286=TAS, GO:0005515=IPI, GO:0048011=TAS, GO:0008284=IGI, GO:0005794=IEA, GO:0048015=TAS, GO:0030916=IEA, GO:0007267=TAS, GO:0005576=TAS, GO:0048538=IEA, GO:0001759=IEA, GO:0048752=IEA, GO:0009653=TAS, GO:0036342=IEA, GO:0007165=TAS, GO:0007173=TAS, GO:0008543=TAS, GO:0045087=TAS, GO:0051781=IEA, GO:0008083=IEA, GO:0055026=IMP} anatomical structure morphogenesis, cell-cell signaling, epidermal growth factor receptor signaling pathway, fibroblast growth factor receptor signaling pathway, innate immune response, insulin receptor signaling pathway, negative regulation of cardiac muscle tissue development, neurotrophin TRK receptor signaling pathway, organ induction, otic vesicle formation, phosphatidylinositol-mediated signaling, positive regulation of cell division, positive regulation of cell proliferation, post-anal tail morphogenesis, semicircular canal morphogenesis, signal transduction, thymus development Golgi apparatus, extracellular region growth factor activity, protein binding Human FGF4 Reactome UniProtKB {GO:0008286=Reactome:REACT_498, GO:0008284=PMID:8663044, GO:0060591=PMID:17167778, GO:0010463=PMID:11023873, GO:0007267=PMID:2959959, GO:0005634=GO_REF:0000019, GO:0005829=GO_REF:0000019, GO:0007173=Reactome:REACT_9417, GO:0045944=GO_REF:0000019, GO:0042475=GO_REF:0000019, GO:0051781=GO_REF:0000037, GO:0070374=PMID:17167778, GO:0008201=GO_REF:0000037, GO:0048011=Reactome:REACT_11061, GO:0043066=GO_REF:0000019, GO:0048015=Reactome:REACT_12464, GO:0005104=GO_REF:0000019, GO:0060561=GO_REF:0000019, GO:0005576=Reactome:REACT_147854, GO:0007165=PMID:2959959, GO:0060363=GO_REF:0000019, GO:0001502=GO_REF:0000019, GO:0008543=Reactome:REACT_9515, GO:0045087=Reactome:REACT_6802, GO:0019827=GO_REF:0000019, GO:0035116=GO_REF:0000019, GO:0001934=GO_REF:0000019, GO:0008083=GO_REF:0000037} P08620 Fibroblast growth factor 4 protein 20130301 {GO:0008286=TAS, GO:0008284=IGI, GO:0060591=IDA, GO:0010463=IDA, GO:0007267=TAS, GO:0005634=IEA, GO:0005829=IEA, GO:0007173=TAS, GO:0045944=IEA, GO:0042475=IEA, GO:0051781=IEA, GO:0070374=IDA, GO:0008201=IEA, GO:0048011=TAS, GO:0043066=IEA, GO:0048015=TAS, GO:0005104=IEA, GO:0060561=IEA, GO:0005576=TAS, GO:0007165=TAS, GO:0060363=IEA, GO:0001502=IEA, GO:0008543=TAS, GO:0045087=TAS, GO:0019827=IEA, GO:0035116=IEA, GO:0001934=IEA, GO:0008083=IEA} apoptotic process involved in morphogenesis, cartilage condensation, cell-cell signaling, chondroblast differentiation, cranial suture morphogenesis, embryonic hindlimb morphogenesis, epidermal growth factor receptor signaling pathway, fibroblast growth factor receptor signaling pathway, innate immune response, insulin receptor signaling pathway, mesenchymal cell proliferation, negative regulation of apoptotic process, neurotrophin TRK receptor signaling pathway, odontogenesis of dentin-containing tooth, phosphatidylinositol-mediated signaling, positive regulation of ERK1 and ERK2 cascade, positive regulation of cell division, positive regulation of cell proliferation, positive regulation of protein phosphorylation, positive regulation of transcription from RNA polymerase II promoter, signal transduction, stem cell maintenance cytosol, extracellular region, nucleus fibroblast growth factor receptor binding, growth factor activity, heparin binding Human FGF5 Reactome UniProtKB {GO:0008286=Reactome:REACT_498, GO:0048011=Reactome:REACT_11061, GO:0008284=PMID:8663044, GO:0023019=GO_REF:0000019, GO:0008283=PMID:3211147, GO:0048015=Reactome:REACT_12464, GO:0007267=PMID:9786939, GO:0005104=PMID:8386828, GO:0005576=Reactome:REACT_147854, GO:0005615=PMID:9786939, GO:0007399=PMID:9786939, GO:0007173=Reactome:REACT_9417, GO:0008543=Reactome:REACT_9515, GO:0045087=Reactome:REACT_6802, GO:0010001=GO_REF:0000019, GO:0051781=GO_REF:0000037, GO:0008083=GO_REF:0000037} P12034 Fibroblast growth factor 5 protein 20130301 {GO:0008286=TAS, GO:0048011=TAS, GO:0008284=IGI, GO:0023019=IEA, GO:0008283=TAS, GO:0048015=TAS, GO:0007267=TAS, GO:0005104=IDA, GO:0005576=TAS, GO:0005615=TAS, GO:0007399=TAS, GO:0007173=TAS, GO:0008543=TAS, GO:0045087=TAS, GO:0010001=IEA, GO:0051781=IEA, GO:0008083=IEA} cell proliferation, cell-cell signaling, epidermal growth factor receptor signaling pathway, fibroblast growth factor receptor signaling pathway, glial cell differentiation, innate immune response, insulin receptor signaling pathway, nervous system development, neurotrophin TRK receptor signaling pathway, phosphatidylinositol-mediated signaling, positive regulation of cell division, positive regulation of cell proliferation, signal transduction involved in regulation of gene expression extracellular region, extracellular space fibroblast growth factor receptor binding, growth factor activity Human FGF6 Reactome UniProtKB {GO:0008286=Reactome:REACT_498, GO:0048011=Reactome:REACT_11061, GO:0008284=PMID:8663044, GO:0008283=PMID:2649847, GO:0048015=Reactome:REACT_12464, GO:0007267=PMID:2649847, GO:0005576=Reactome:REACT_147854, GO:0001525=GO_REF:0000037, GO:0005615=GO_REF:0000039, GO:0042383=GO_REF:0000019, GO:0007165=PMID:2649847, GO:0007173=Reactome:REACT_9417, GO:0001502=GO_REF:0000019, GO:0008543=Reactome:REACT_9515, GO:0045087=Reactome:REACT_6802, GO:0051781=GO_REF:0000037, GO:0045445=GO_REF:0000019, GO:0008083=GO_REF:0000037} P10767 Fibroblast growth factor 6 protein 20130301 {GO:0008286=TAS, GO:0048011=TAS, GO:0008284=IGI, GO:0008283=TAS, GO:0048015=TAS, GO:0007267=TAS, GO:0005576=TAS, GO:0001525=IEA, GO:0005615=IEA, GO:0042383=IEA, GO:0007165=TAS, GO:0007173=TAS, GO:0001502=IEA, GO:0008543=TAS, GO:0045087=TAS, GO:0051781=IEA, GO:0045445=IEA, GO:0008083=IEA} angiogenesis, cartilage condensation, cell proliferation, cell-cell signaling, epidermal growth factor receptor signaling pathway, fibroblast growth factor receptor signaling pathway, innate immune response, insulin receptor signaling pathway, myoblast differentiation, neurotrophin TRK receptor signaling pathway, phosphatidylinositol-mediated signaling, positive regulation of cell division, positive regulation of cell proliferation, signal transduction extracellular region, extracellular space, sarcolemma growth factor activity Human FGF7 IntAct UniProtKB {GO:0005515=PMID:1309608, GO:0008286=Reactome:REACT_498, GO:0010838=PMID:17449030, GO:0008284=PMID:8663044, GO:0051549=PMID:17449030, GO:0010463=PMID:11023837, GO:0050731=PMID:17449030, GO:0031069=GO_REF:0000019, GO:0060665=GO_REF:0000019, GO:0007173=Reactome:REACT_9417, GO:0060501=PMID:9740653, GO:0051781=GO_REF:0000037, GO:0008201=GO_REF:0000037, GO:0050679=PMID:11493558, GO:0048011=Reactome:REACT_11061, GO:0005794=GO_REF:0000019, GO:0031532=PMID:17449030, GO:0048015=Reactome:REACT_12464, GO:0009611=PMID:7973639, GO:0005576=Reactome:REACT_147854, GO:0042056=PMID:17449030, GO:0050918=PMID:17449030, GO:0007165=PMID:2475908, GO:0008544=PMID:7973639, GO:0008543=Reactome:REACT_9470, GO:0045087=Reactome:REACT_6802, GO:0034394=PMID:17449030, GO:0008083=GO_REF:0000037, GO:0061033=PMID:10541313, GO:0060445=GO_REF:0000019} P21781 Fibroblast growth factor 7 protein 20130415 {GO:0005515=IPI, GO:0008286=TAS, GO:0010838=IDA, GO:0008284=IGI, GO:0051549=IDA, GO:0010463=IDA, GO:0050731=IDA, GO:0031069=IEA, GO:0060665=IEA, GO:0007173=TAS, GO:0060501=IDA, GO:0051781=IEA, GO:0008201=IEA, GO:0050679=IDA, GO:0048011=TAS, GO:0005794=IEA, GO:0031532=IDA, GO:0048015=TAS, GO:0009611=TAS, GO:0005576=TAS, GO:0042056=IDA, GO:0050918=IDA, GO:0007165=NAS, GO:0008544=TAS, GO:0008543=TAS, GO:0045087=TAS, GO:0034394=IDA, GO:0008083=IEA, GO:0061033=IDA, GO:0060445=IEA} actin cytoskeleton reorganization, branching involved in salivary gland morphogenesis, epidermal growth factor receptor signaling pathway, epidermis development, fibroblast growth factor receptor signaling pathway, hair follicle morphogenesis, innate immune response, insulin receptor signaling pathway, mesenchymal cell proliferation, neurotrophin TRK receptor signaling pathway, phosphatidylinositol-mediated signaling, positive chemotaxis, positive regulation of cell division, positive regulation of cell proliferation, positive regulation of epithelial cell proliferation, positive regulation of epithelial cell proliferation involved in lung morphogenesis, positive regulation of keratinocyte migration, positive regulation of keratinocyte proliferation, positive regulation of peptidyl-tyrosine phosphorylation, protein localization to cell surface, regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling, response to wounding, secretion by lung epithelial cell involved in lung growth, signal transduction Golgi apparatus, extracellular region chemoattractant activity, growth factor activity, heparin binding, protein binding Human UniProtKB:P21802-3 FGF8 BHF-UCL UniProtKB {GO:0001656=PMID:18437684, GO:0008406=PMID:18596921, GO:0001658=GO_REF:0000019, GO:0030878=GO_REF:0000019, GO:0001759=GO_REF:0000019, GO:0009653=PMID:8595889, GO:0001947=GO_REF:0000019, GO:0030539=GO_REF:0000019, GO:0043524=GO_REF:0000019, GO:0007173=Reactome:REACT_9417, GO:0021798=GO_REF:0000019, GO:0000165=GO_REF:0000019, GO:0051781=GO_REF:0000037, GO:0021543=GO_REF:0000019, GO:0023019=GO_REF:0000019, GO:0030916=GO_REF:0000019, GO:0021544=GO_REF:0000019, GO:0045840=GO_REF:0000019, GO:0030509=GO_REF:0000019, GO:0060037=GO_REF:0000019, GO:0060348=PMID:18596921, GO:0008543=Reactome:REACT_9515, GO:0045087=Reactome:REACT_6802, GO:0030917=GO_REF:0000019, GO:0008083=GO_REF:0000037, GO:0060445=GO_REF:0000019, GO:0008286=Reactome:REACT_498, GO:0021846=GO_REF:0000019, GO:0008284=GO_REF:0000019, GO:0007369=PMID:8700553, GO:0060425=GO_REF:0000019, GO:0001839=GO_REF:0000019, GO:0060129=GO_REF:0000019, GO:0060128=GO_REF:0000019, GO:0008078=GO_REF:0000019, GO:0042476=PMID:17394220, GO:0060070=GO_REF:0000019, GO:0055026=PMID:20702560, GO:0048011=Reactome:REACT_11061, GO:0001569=GO_REF:0000019, GO:0090134=GO_REF:0000019, GO:0046622=GO_REF:0000019, GO:0003198=GO_REF:0000024, GO:0048015=Reactome:REACT_12464, GO:0001823=PMID:18437684, GO:0035909=GO_REF:0000019, GO:0060563=PMID:17309880, GO:0006915=GO_REF:0000019, GO:0005576=Reactome:REACT_147854, GO:0048853=GO_REF:0000019, GO:0010628=GO_REF:0000019, GO:0001974=GO_REF:0000019, GO:0071542=PMID:15193767, GO:0003148=GO_REF:0000024, GO:0035116=GO_REF:0000019, GO:0042487=GO_REF:0000019} P55075 Fibroblast growth factor 8 protein 20120727 {GO:0001656=IEP, GO:0008406=IMP, GO:0001658=IEA, GO:0030878=IEA, GO:0001759=IEA, GO:0009653=NAS, GO:0001947=IEA, GO:0030539=IEA, GO:0043524=IEA, GO:0007173=TAS, GO:0021798=IEA, GO:0000165=IEA, GO:0051781=IEA, GO:0021543=IEA, GO:0023019=IEA, GO:0030916=IEA, GO:0021544=IEA, GO:0045840=IEA, GO:0030509=IEA, GO:0060037=IEA, GO:0060348=IMP, GO:0008543=TAS, GO:0045087=TAS, GO:0030917=IEA, GO:0008083=IEA, GO:0060445=IEA, GO:0008286=TAS, GO:0021846=IEA, GO:0008284=IEA, GO:0007369=NAS, GO:0060425=IEA, GO:0001839=IEA, GO:0060129=IEA, GO:0060128=IEA, GO:0008078=IEA, GO:0042476=IEP, GO:0060070=IEA, GO:0055026=IMP, GO:0048011=TAS, GO:0001569=IEA, GO:0090134=IEA, GO:0046622=IEA, GO:0003198=ISS, GO:0048015=TAS, GO:0001823=IEP, GO:0035909=IEA, GO:0060563=IDA, GO:0006915=IEA, GO:0005576=TAS, GO:0048853=IEA, GO:0010628=IEA, GO:0001974=IEA, GO:0071542=IDA, GO:0003148=ISS, GO:0035116=IEA, GO:0042487=IEA} BMP signaling pathway, MAPK cascade, anatomical structure morphogenesis, aorta morphogenesis, apoptotic process, blood vessel remodeling, bone development, branching involved in salivary gland morphogenesis, branching involved in ureteric bud morphogenesis, canonical Wnt receptor signaling pathway, cell migration involved in mesendoderm migration, cell proliferation in forebrain, corticotropin hormone secreting cell differentiation, dopaminergic neuron differentiation, embryonic hindlimb morphogenesis, epidermal growth factor receptor signaling pathway, epithelial to mesenchymal transition involved in endocardial cushion formation, fibroblast growth factor receptor signaling pathway, forebrain dorsal/ventral pattern formation, forebrain morphogenesis, gastrulation, gonad development, heart looping, innate immune response, insulin receptor signaling pathway, lung morphogenesis, male genitalia development, mesodermal cell migration, mesonephros development, metanephros development, midbrain-hindbrain boundary development, negative regulation of cardiac muscle tissue development, negative regulation of neuron apoptotic process, neural plate morphogenesis, neuroepithelial cell differentiation, neurotrophin TRK receptor signaling pathway, odontogenesis, organ induction, otic vesicle formation, outflow tract septum morphogenesis, pallium development, patterning of blood vessels, pharyngeal system development, phosphatidylinositol-mediated signaling, positive regulation of cell division, positive regulation of cell proliferation, positive regulation of gene expression, positive regulation of mitosis, positive regulation of organ growth, regulation of odontogenesis of dentin-containing tooth, signal transduction involved in regulation of gene expression, subpallium development, thyroid gland development, thyroid-stimulating hormone-secreting cell differentiation extracellular region growth factor activity Human UniProtKB:P37237 FGF9 Reactome UniProtKB {GO:0008286=Reactome:REACT_498, GO:0060045=GO_REF:0000019, GO:0030949=GO_REF:0000019, GO:0008284=PMID:8321227, GO:0090263=GO_REF:0000019, GO:0007267=GO_REF:0000019, GO:0030178=GO_REF:0000019, GO:0048706=GO_REF:0000019, GO:0030326=GO_REF:0000019, GO:0006606=GO_REF:0000019, GO:0005615=PMID:8321227, GO:0045880=GO_REF:0000019, GO:0005737=GO_REF:0000019, GO:0007173=Reactome:REACT_9417, GO:0002062=GO_REF:0000019, GO:0030238=GO_REF:0000019, GO:0051781=GO_REF:0000037, GO:0008201=GO_REF:0000037, GO:0050679=GO_REF:0000019, GO:0048505=GO_REF:0000019, GO:0048011=Reactome:REACT_11061, GO:0042472=GO_REF:0000019, GO:0048015=Reactome:REACT_12464, GO:0005576=Reactome:REACT_9519, GO:0005104=GO_REF:0000019, GO:0002053=GO_REF:0000019, GO:0001525=GO_REF:0000019, GO:0048566=GO_REF:0000019, GO:0001649=GO_REF:0000019, GO:0005604=GO_REF:0000019, GO:0010628=GO_REF:0000019, GO:0007165=PMID:8575785, GO:0008543=Reactome:REACT_9515, GO:0045087=Reactome:REACT_6802, GO:0060484=GO_REF:0000019, GO:0043410=GO_REF:0000019, GO:0008083=GO_REF:0000019, GO:0008584=PMID:17848411} P31371 Fibroblast growth factor 9 protein 20110530 {GO:0008286=TAS, GO:0060045=IEA, GO:0030949=IEA, GO:0008284=IDA, GO:0090263=IEA, GO:0007267=IEA, GO:0030178=IEA, GO:0048706=IEA, GO:0030326=IEA, GO:0006606=IEA, GO:0005615=IDA, GO:0045880=IEA, GO:0005737=IEA, GO:0007173=TAS, GO:0002062=IEA, GO:0030238=IEA, GO:0051781=IEA, GO:0008201=IEA, GO:0050679=IEA, GO:0048505=IEA, GO:0048011=TAS, GO:0042472=IEA, GO:0048015=TAS, GO:0005576=TAS, GO:0005104=IEA, GO:0002053=IEA, GO:0001525=IEA, GO:0048566=IEA, GO:0001649=IEA, GO:0005604=IEA, GO:0010628=IEA, GO:0007165=TAS, GO:0008543=TAS, GO:0045087=TAS, GO:0060484=IEA, GO:0043410=IEA, GO:0008083=IEA, GO:0008584=IEP} angiogenesis, cell-cell signaling, chondrocyte differentiation, embryonic digestive tract development, embryonic limb morphogenesis, embryonic skeletal system development, epidermal growth factor receptor signaling pathway, fibroblast growth factor receptor signaling pathway, innate immune response, inner ear morphogenesis, insulin receptor signaling pathway, lung-associated mesenchyme development, male gonad development, male sex determination, negative regulation of Wnt receptor signaling pathway, neurotrophin TRK receptor signaling pathway, osteoblast differentiation, phosphatidylinositol-mediated signaling, positive regulation of MAPK cascade, positive regulation of canonical Wnt receptor signaling pathway, positive regulation of cardiac muscle cell proliferation, positive regulation of cell division, positive regulation of cell proliferation, positive regulation of epithelial cell proliferation, positive regulation of gene expression, positive regulation of mesenchymal cell proliferation, positive regulation of smoothened signaling pathway, positive regulation of vascular endothelial growth factor receptor signaling pathway, protein import into nucleus, regulation of timing of cell differentiation, signal transduction basement membrane, cytoplasm, extracellular region, extracellular space fibroblast growth factor receptor binding, growth factor activity, heparin binding Human FGFBP1 IntAct UniProtKB {GO:0005515=PMID:16257968, GO:0007165=PMID:1885605, GO:0008284=GO_REF:0000019, GO:0008285=PMID:1885605, GO:0005886=GO_REF:0000039, GO:0045743=GO_REF:0000019, GO:0009986=GO_REF:0000019, GO:0017134=GO_REF:0000019, GO:0007267=PMID:1885605, GO:0008201=PMID:1885605, GO:0005615=GO_REF:0000039} Q14512 Fibroblast growth factor-binding protein 1 protein 20130415 {GO:0005515=IPI, GO:0007165=NAS, GO:0008284=IEA, GO:0008285=TAS, GO:0005886=IEA, GO:0045743=IEA, GO:0009986=IEA, GO:0017134=IEA, GO:0007267=TAS, GO:0008201=TAS, GO:0005615=IEA} cell-cell signaling, negative regulation of cell proliferation, positive regulation of cell proliferation, positive regulation of fibroblast growth factor receptor signaling pathway, signal transduction cell surface, extracellular space, plasma membrane fibroblast growth factor binding, heparin binding, protein binding Human UniProtKB:P09038 FGFBP2 UniProtKB UniProtKB {GO:0019838=GO_REF:0000037, GO:0005615=GO_REF:0000039} Q9BYJ0 Fibroblast growth factor-binding protein 2 protein 20130413 {GO:0019838=IEA, GO:0005615=IEA} extracellular space growth factor binding Human UniProtKB-SubCell:SL-0112 FGFR1 IntAct UniProtKB {GO:0060045=GO_REF:0000019, GO:0005515=PMID:19665973, GO:0001657=GO_REF:0000019, GO:0007605=GO_REF:0000019, GO:0048705=PMID:15863030, GO:0001759=GO_REF:0000019, GO:0042803=PMID:20133753, GO:0042802=PMID:19696444, GO:0046777=PMID:8622701, GO:0007173=Reactome:REACT_9417, GO:0007411=Reactome:REACT_18266, GO:0000165=PMID:10748122, GO:0002062=GO_REF:0000019, GO:0048339=GO_REF:0000019, GO:0042472=GO_REF:0000019, GO:0017134=PMID:18480409, GO:0010518=PMID:12141425, GO:0018108=PMID:18480409, GO:0014068=PMID:15863030, GO:0000122=GO_REF:0000019, GO:0001701=GO_REF:0000019, GO:0045787=GO_REF:0000019, GO:0001501=PMID:7874169, GO:0005887=PMID:10918587, GO:0008543=Reactome:REACT_9515, GO:0045087=Reactome:REACT_6802, GO:0010976=GO_REF:0000019, GO:0045595=PMID:12141425, GO:0060484=GO_REF:0000019, GO:0060445=GO_REF:0000019, GO:0008286=Reactome:REACT_498, GO:0021847=GO_REF:0000019, GO:0008284=PMID:8663044, GO:0005886=Reactome:REACT_147854, GO:0005634=GO_REF:0000039, GO:0030326=GO_REF:0000019, GO:0043009=PMID:15863030, GO:0005829=GO_REF:0000039, GO:0048378=GO_REF:0000019, GO:0060665=GO_REF:0000019, GO:0043406=PMID:18480409, GO:0048469=GO_REF:0000019, GO:0042474=GO_REF:0000019, GO:0042473=GO_REF:0000019, GO:0008201=PMID:18480409, GO:0005007=PMID:18480409, GO:0048011=Reactome:REACT_11061, GO:0043066=GO_REF:0000019, GO:0048015=Reactome:REACT_12464, GO:0048762=GO_REF:0000019, GO:0002053=GO_REF:0000019, GO:0005576=PMID:1652059, GO:0001525=GO_REF:0000019, GO:0005524=GO_REF:0000037, GO:0035607=GO_REF:0000019, GO:0006351=GO_REF:0000037, GO:0010863=PMID:18480409, GO:0060117=GO_REF:0000019, GO:0016477=PMID:15863030, GO:0045666=PMID:8622701, GO:0016023=GO_REF:0000039, GO:0030901=GO_REF:0000019, GO:0006468=PMID:1846977, GO:0016021=PMID:1652059, GO:0004713=PMID:8622701, GO:0001764=PMID:15863030, GO:0043410=PMID:8622701, GO:0090080=GO_REF:0000019} P11362 Fibroblast growth factor receptor 1 protein 20130415 {GO:0060045=IEA, GO:0005515=IPI, GO:0001657=IEA, GO:0007605=IEA, GO:0048705=TAS, GO:0001759=IEA, GO:0042803=IPI, GO:0042802=IPI, GO:0046777=IDA, GO:0007173=TAS, GO:0007411=TAS, GO:0000165=TAS, GO:0002062=IEA, GO:0048339=IEA, GO:0042472=IEA, GO:0017134=IDA, GO:0010518=TAS, GO:0018108=IDA, GO:0014068=TAS, GO:0000122=IEA, GO:0001701=IEA, GO:0045787=IEA, GO:0001501=TAS, GO:0005887=TAS, GO:0008543=TAS, GO:0045087=TAS, GO:0010976=IEA, GO:0045595=TAS, GO:0060484=IEA, GO:0060445=IEA, GO:0008286=TAS, GO:0021847=IEA, GO:0008284=IGI, GO:0005886=TAS, GO:0005634=IEA, GO:0030326=IEA, GO:0043009=TAS, GO:0005829=IEA, GO:0048378=IEA, GO:0060665=IEA, GO:0043406=IDA, GO:0048469=IEA, GO:0042474=IEA, GO:0042473=IEA, GO:0008201=IDA, GO:0005007=IDA, GO:0048011=TAS, GO:0043066=IEA, GO:0048015=TAS, GO:0048762=IEA, GO:0002053=IEA, GO:0005576=NAS, GO:0001525=IEA, GO:0005524=IEA, GO:0035607=IEA, GO:0006351=IEA, GO:0010863=IDA, GO:0060117=IEA, GO:0016477=TAS, GO:0045666=IMP, GO:0016023=IEA, GO:0030901=IEA, GO:0006468=NAS, GO:0016021=NAS, GO:0004713=IDA, GO:0001764=TAS, GO:0043410=IMP, GO:0090080=IEA} MAPK cascade, angiogenesis, auditory receptor cell development, axon guidance, branching involved in salivary gland morphogenesis, cell maturation, cell migration, chondrocyte differentiation, chordate embryonic development, embryonic limb morphogenesis, epidermal growth factor receptor signaling pathway, fibroblast growth factor receptor signaling pathway, fibroblast growth factor receptor signaling pathway involved in orbitofrontal cortex development, in utero embryonic development, innate immune response, inner ear morphogenesis, insulin receptor signaling pathway, lung-associated mesenchyme development, mesenchymal cell differentiation, midbrain development, middle ear morphogenesis, negative regulation of apoptotic process, negative regulation of transcription from RNA polymerase II promoter, neuron migration, neurotrophin TRK receptor signaling pathway, organ induction, outer ear morphogenesis, paraxial mesoderm development, peptidyl-tyrosine phosphorylation, phosphatidylinositol-mediated signaling, positive regulation of MAP kinase activity, positive regulation of MAPK cascade, positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway, positive regulation of cardiac muscle cell proliferation, positive regulation of cell cycle, positive regulation of cell proliferation, positive regulation of mesenchymal cell proliferation, positive regulation of neuron differentiation, positive regulation of neuron projection development, positive regulation of phosphatidylinositol 3-kinase cascade, positive regulation of phospholipase C activity, positive regulation of phospholipase activity, protein autophosphorylation, protein phosphorylation, regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling, regulation of cell differentiation, regulation of lateral mesodermal cell fate specification, sensory perception of sound, skeletal system development, skeletal system morphogenesis, transcription, DNA-dependent, ureteric bud development, ventricular zone neuroblast division cytoplasmic membrane-bounded vesicle, cytosol, extracellular region, integral to membrane, integral to plasma membrane, nucleus, plasma membrane ATP binding, fibroblast growth factor binding, fibroblast growth factor-activated receptor activity, heparin binding, identical protein binding, protein binding, protein homodimerization activity, protein tyrosine kinase activity Human UniProtKB:P11362 FGFR1OP GOC UniProtKB {GO:0005515=PMID:17888034, GO:0005813=PMID:21399614, GO:0008284=PMID:17888034, GO:0048471=PMID:17888034, GO:0030335=PMID:17888034, GO:0034453=GO_REF:0000002, GO:0019901=PMID:17888034, GO:0030307=PMID:17888034, GO:0061099=PMID:17888034, GO:0030292=PMID:17888034, GO:0005634=PMID:17888034, GO:0042803=PMID:16690081, GO:0005829=Reactome:REACT_121382, GO:0000086=Reactome:REACT_2203, GO:0004713=Reactome:REACT_121233, GO:0006469=PMID:17888034, GO:0000278=Reactome:REACT_152} O95684 FGFR1 oncogene partner protein 20130413 {GO:0005515=IPI, GO:0005813=IDA, GO:0008284=IDA, GO:0048471=IDA, GO:0030335=IDA, GO:0034453=IEA, GO:0019901=IPI, GO:0030307=IDA, GO:0061099=IDA, GO:0030292=IDA, GO:0005634=IDA, GO:0042803=IDA, GO:0005829=TAS, GO:0000086=TAS, GO:0004713=TAS, GO:0006469=IDA, GO:0000278=TAS} G2/M transition of mitotic cell cycle, microtubule anchoring, mitotic cell cycle, negative regulation of protein kinase activity, negative regulation of protein tyrosine kinase activity, positive regulation of cell growth, positive regulation of cell migration, positive regulation of cell proliferation centrosome, cytosol, nucleus, perinuclear region of cytoplasm protein binding, protein homodimerization activity, protein kinase binding, protein tyrosine kinase activity, protein tyrosine kinase inhibitor activity Human FGFR1OP2 Reactome UniProtKB {GO:0005737=GO_REF:0000019, GO:0042060=GO_REF:0000019, GO:0042803=GO_REF:0000019, GO:0005829=Reactome:REACT_121382} Q9NVK5 FGFR1 oncogene partner 2 protein 20121108 {GO:0005737=IEA, GO:0042060=IEA, GO:0042803=IEA, GO:0005829=TAS} wound healing cytoplasm, cytosol protein homodimerization activity Human FGFR2 HPA UniProtKB {GO:0005515=PMID:22726438, GO:0060045=GO_REF:0000024, GO:0090263=GO_REF:0000024, GO:0048705=PMID:15190072, GO:0009791=GO_REF:0000024, GO:0048701=PMID:7874170, GO:0021860=GO_REF:0000024, GO:0031069=GO_REF:0000024, GO:0060916=GO_REF:0000024, GO:0060915=GO_REF:0000024, GO:0046777=PMID:15629145, GO:0005794=GO_REF:0000039, GO:0042472=GO_REF:0000024, GO:0051150=GO_REF:0000024, GO:0009986=PMID:12493773, GO:0010518=PMID:16844695, GO:0018108=PMID:16844695, GO:0001701=GO_REF:0000024, GO:0060442=GO_REF:0000024, GO:0060348=GO_REF:0000024, GO:0045165=GO_REF:0000024, GO:0005887=PMID:16844695, GO:0045087=Reactome:REACT_6802, GO:0060349=GO_REF:0000024, GO:0060449=GO_REF:0000024, GO:0060445=GO_REF:0000024, GO:0060595=GO_REF:0000024, GO:0060529=GO_REF:0000024, GO:0021847=GO_REF:0000024, GO:0030177=GO_REF:0000024, GO:0005634=PMID:17471512, GO:0007528=GO_REF:0000019, GO:0060664=GO_REF:0000024, GO:0060667=GO_REF:0000024, GO:0048568=GO_REF:0000024, GO:0040014=GO_REF:0000024, GO:0042476=GO_REF:0000024, GO:0060523=GO_REF:0000024, GO:0060527=GO_REF:0000024, GO:0035604=GO_REF:0000024, GO:0048011=Reactome:REACT_11061, GO:0035603=GO_REF:0000024, GO:0035602=GO_REF:0000024, GO:0048015=Reactome:REACT_12464, GO:0048762=GO_REF:0000024, GO:0005576=GO_REF:0000039, GO:0048565=GO_REF:0000024, GO:0035607=GO_REF:0000024, GO:0048562=GO_REF:0000024, GO:0032808=GO_REF:0000024, GO:0045667=PMID:15190072, GO:0016020=PMID:8676562, GO:0040036=GO_REF:0000024, GO:0048557=GO_REF:0000024, GO:0060463=GO_REF:0000024, GO:0060512=GO_REF:0000024, GO:0016023=GO_REF:0000039, GO:0030901=GO_REF:0000024, GO:0048755=GO_REF:0000024, GO:0016021=PMID:1697263, GO:0061031=GO_REF:0000019, GO:0001657=GO_REF:0000024, GO:0033688=PMID:15190072, GO:0055010=GO_REF:0000024, GO:0070307=GO_REF:0000019, GO:0060670=GO_REF:0000024, GO:0007409=GO_REF:0000024, GO:0042803=PMID:16844695, GO:0042802=PMID:22726438, GO:0009880=GO_REF:0000024, GO:0048608=GO_REF:0000024, GO:0007173=Reactome:REACT_9417, GO:0060501=GO_REF:0000024, GO:0009887=GO_REF:0000024, GO:0051781=GO_REF:0000024, GO:0060601=GO_REF:0000024, GO:0070374=GO_REF:0000024, GO:0070372=GO_REF:0000024, GO:0005938=PMID:17471512, GO:0050679=GO_REF:0000024, GO:0048286=GO_REF:0000024, GO:0017134=PMID:8386828, GO:0010453=GO_REF:0000024, GO:0030916=GO_REF:0000024, GO:0048489=GO_REF:0000019, GO:0000122=GO_REF:0000024, GO:0060688=GO_REF:0000024, GO:0045787=GO_REF:0000024, GO:0060076=GO_REF:0000024, GO:0060687=GO_REF:0000024, GO:0045839=GO_REF:0000019, GO:0008543=Reactome:REACT_9470, GO:0060174=GO_REF:0000024, GO:0060484=GO_REF:0000024, GO:0008286=Reactome:REACT_498, GO:0008284=PMID:8663044, GO:0008285=GO_REF:0000019, GO:0005886=GO_REF:0000052, GO:0030324=GO_REF:0000024, GO:0007267=GO_REF:0000024, GO:0030282=GO_REF:0000024, GO:0048730=GO_REF:0000024, GO:0005737=PMID:17471512, GO:0035264=GO_REF:0000024, GO:0035265=GO_REF:0000024, GO:0045944=GO_REF:0000024, GO:0030855=GO_REF:0000024, GO:0022612=GO_REF:0000024, GO:0008201=GO_REF:0000037, GO:0005007=PMID:10830168, GO:0006915=GO_REF:0000037, GO:0002053=GO_REF:0000024, GO:0001525=GO_REF:0000024, GO:0005524=GO_REF:0000037, GO:0031012=PMID:17959718, GO:0060365=GO_REF:0000019, GO:0016331=GO_REF:0000024, GO:0008589=GO_REF:0000024, GO:0003149=GO_REF:0000024, GO:0003148=GO_REF:0000024, GO:0060615=GO_REF:0000024, GO:0004713=PMID:1697263, GO:0043410=PMID:15629145, GO:0021769=GO_REF:0000024} P21802 Fibroblast growth factor receptor 2 protein 20120912 {GO:0005515=IPI, GO:0060045=ISS, GO:0090263=ISS, GO:0048705=TAS, GO:0009791=ISS, GO:0048701=IMP, GO:0021860=ISS, GO:0031069=ISS, GO:0060916=ISS, GO:0060915=ISS, GO:0046777=IDA, GO:0005794=IEA, GO:0042472=ISS, GO:0051150=ISS, GO:0009986=IDA, GO:0010518=IMP, GO:0018108=IDA, GO:0001701=ISS, GO:0060442=ISS, GO:0060348=ISS, GO:0045165=ISS, GO:0005887=IDA, GO:0045087=TAS, GO:0060349=ISS, GO:0060449=ISS, GO:0060445=ISS, GO:0060595=ISS, GO:0060529=ISS, GO:0021847=ISS, GO:0030177=ISS, GO:0005634=IDA, GO:0007528=IEA, GO:0060664=ISS, GO:0060667=ISS, GO:0048568=ISS, GO:0040014=ISS, GO:0042476=ISS, GO:0060523=ISS, GO:0060527=ISS, GO:0035604=ISS, GO:0048011=TAS, GO:0035603=ISS, GO:0035602=ISS, GO:0048015=TAS, GO:0048762=ISS, GO:0005576=IEA, GO:0048565=ISS, GO:0035607=ISS, GO:0048562=ISS, GO:0032808=ISS, GO:0045667=TAS, GO:0016020=NAS, GO:0040036=ISS, GO:0048557=ISS, GO:0060463=ISS, GO:0060512=ISS, GO:0016023=IEA, GO:0030901=ISS, GO:0048755=ISS, GO:0016021=NAS, GO:0061031=IEA, GO:0001657=ISS, GO:0033688=TAS, GO:0055010=ISS, GO:0070307=IEA, GO:0060670=ISS, GO:0007409=ISS, GO:0042803=IPI, GO:0042802=IPI, GO:0009880=ISS, GO:0048608=ISS, GO:0007173=TAS, GO:0060501=ISS, GO:0009887=ISS, GO:0051781=ISS, GO:0060601=ISS, GO:0070374=ISS, GO:0070372=ISS, GO:0005938=IDA, GO:0050679=ISS, GO:0048286=ISS, GO:0017134=IPI, GO:0010453=ISS, GO:0030916=ISS, GO:0048489=IEA, GO:0000122=ISS, GO:0060688=ISS, GO:0045787=ISS, GO:0060076=ISS, GO:0060687=ISS, GO:0045839=IEA, GO:0008543=TAS, GO:0060174=ISS, GO:0060484=ISS, GO:0008286=TAS, GO:0008284=IGI, GO:0008285=IEA, GO:0005886=IDA, GO:0030324=ISS, GO:0007267=ISS, GO:0030282=ISS, GO:0048730=ISS, GO:0005737=IDA, GO:0035264=ISS, GO:0035265=ISS, GO:0045944=ISS, GO:0030855=ISS, GO:0022612=ISS, GO:0008201=IEA, GO:0005007=IGI, GO:0006915=IEA, GO:0002053=ISS, GO:0001525=ISS, GO:0005524=IEA, GO:0031012=IDA, GO:0060365=IEA, GO:0016331=ISS, GO:0008589=ISS, GO:0003149=ISS, GO:0003148=ISS, GO:0060615=ISS, GO:0004713=NAS, GO:0043410=IMP, GO:0021769=ISS} angiogenesis, apoptotic process, axonogenesis, bone development, bone mineralization, bone morphogenesis, branch elongation involved in salivary gland morphogenesis, branching involved in labyrinthine layer morphogenesis, branching involved in prostate gland morphogenesis, branching involved in salivary gland morphogenesis, branching morphogenesis of a nerve, bud elongation involved in lung branching, cell fate commitment, cell-cell signaling, coronal suture morphogenesis, digestive tract development, embryonic cranial skeleton morphogenesis, embryonic digestive tract morphogenesis, embryonic organ development, embryonic organ morphogenesis, embryonic pattern specification, endodermal digestive tract morphogenesis, epidermal growth factor receptor signaling pathway, epidermis morphogenesis, epithelial cell differentiation, epithelial cell proliferation involved in salivary gland morphogenesis, fibroblast growth factor receptor signaling pathway, fibroblast growth factor receptor signaling pathway involved in hemopoiesis, fibroblast growth factor receptor signaling pathway involved in mammary gland specification, fibroblast growth factor receptor signaling pathway involved in negative regulation of apoptotic process in bone marrow, fibroblast growth factor receptor signaling pathway involved in orbitofrontal cortex development, fibroblast growth factor receptor signaling pathway involved in positive regulation of cell proliferation in bone marrow, gland morphogenesis, hair follicle morphogenesis, in utero embryonic development, innate immune response, inner ear morphogenesis, insulin receptor signaling pathway, lacrimal gland development, lateral sprouting from an epithelium, lens fiber cell development, limb bud formation, lung alveolus development, lung development, lung lobe morphogenesis, lung-associated mesenchyme development, mammary gland bud formation, membranous septum morphogenesis, mesenchymal cell differentiation, mesenchymal cell differentiation involved in lung development, mesenchymal cell proliferation involved in lung development, midbrain development, morphogenesis of embryonic epithelium, multicellular organism growth, negative regulation of cell proliferation, negative regulation of mitosis, negative regulation of transcription from RNA polymerase II promoter, neuromuscular junction development, neurotrophin TRK receptor signaling pathway, odontogenesis, orbitofrontal cortex development, organ growth, organ morphogenesis, otic vesicle formation, outflow tract septum morphogenesis, peptidyl-tyrosine phosphorylation, phosphatidylinositol-mediated signaling, positive regulation of ERK1 and ERK2 cascade, positive regulation of MAPK cascade, positive regulation of Wnt receptor signaling pathway, positive regulation of canonical Wnt receptor signaling pathway, positive regulation of cardiac muscle cell proliferation, positive regulation of cell cycle, positive regulation of cell division, positive regulation of cell proliferation, positive regulation of epithelial cell proliferation, positive regulation of epithelial cell proliferation involved in lung morphogenesis, positive regulation of mesenchymal cell proliferation, positive regulation of phospholipase activity, positive regulation of transcription from RNA polymerase II promoter, post-embryonic development, prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis, prostate epithelial cord elongation, prostate gland morphogenesis, protein autophosphorylation, pyramidal neuron development, regulation of ERK1 and ERK2 cascade, regulation of branching involved in prostate gland morphogenesis, regulation of cell fate commitment, regulation of fibroblast growth factor receptor signaling pathway, regulation of morphogenesis of a branching structure, regulation of multicellular organism growth, regulation of osteoblast differentiation, regulation of osteoblast proliferation, regulation of smooth muscle cell differentiation, regulation of smoothened signaling pathway, reproductive structure development, skeletal system morphogenesis, squamous basal epithelial stem cell differentiation involved in prostate gland acinus development, synaptic vesicle transport, ureteric bud development, ventricular cardiac muscle tissue morphogenesis, ventricular zone neuroblast division Golgi apparatus, cell cortex, cell surface, cytoplasm, cytoplasmic membrane-bounded vesicle, excitatory synapse, extracellular matrix, extracellular region, integral to membrane, integral to plasma membrane, membrane, nucleus, plasma membrane ATP binding, fibroblast growth factor binding, fibroblast growth factor-activated receptor activity, heparin binding, identical protein binding, protein binding, protein homodimerization activity, protein tyrosine kinase activity Human FGFR3 BHF-UCL UniProtKB {GO:0005515=PMID:22939624, GO:0003416=PMID:15748888, GO:0070307=GO_REF:0000019, GO:0045597=GO_REF:0000019, GO:0090263=GO_REF:0000019, GO:0050680=GO_REF:0000019, GO:0035988=PMID:15748888, GO:0005764=GO_REF:0000019, GO:0048678=GO_REF:0000019, GO:0061144=GO_REF:0000019, GO:0046777=PMID:11294897, GO:0007173=Reactome:REACT_9417, GO:0043552=PMID:15748888, GO:0002062=PMID:15748888, GO:0000165=GO_REF:0000019, GO:0031398=GO_REF:0000019, GO:0070374=PMID:11294897, GO:0017134=PMID:8663044, GO:0010518=PMID:17561467, GO:0018108=PMID:11294897, GO:0000122=GO_REF:0000019, GO:0048546=GO_REF:0000019, GO:0048640=PMID:20582225, GO:0045839=GO_REF:0000019, GO:0072148=GO_REF:0000019, GO:0001501=PMID:8601314, GO:0001958=PMID:15748888, GO:0008543=Reactome:REACT_9510, GO:0005887=PMID:8663044, GO:0045087=Reactome:REACT_6802, GO:0060349=PMID:15748888, GO:0060385=GO_REF:0000019, GO:0009898=GO_REF:0000019, GO:0005925=PMID:15748888, GO:0008286=Reactome:REACT_498, GO:0048471=GO_REF:0000019, GO:0008284=PMID:8663044, GO:0005886=Reactome:REACT_147854, GO:0022010=GO_REF:0000019, GO:0005783=GO_REF:0000039, GO:0045879=GO_REF:0000019, GO:0002089=GO_REF:0000019, GO:0090102=GO_REF:0000019, GO:0035019=GO_REF:0000019, GO:0005007=PMID:8663044, GO:0048011=Reactome:REACT_11061, GO:0043066=GO_REF:0000019, GO:0043065=GO_REF:0000019, GO:0060113=GO_REF:0000019, GO:0048015=Reactome:REACT_12464, GO:0042517=PMID:11294897, GO:0042511=PMID:17561467, GO:0006915=GO_REF:0000037, GO:0042981=PMID:17561467, GO:0070977=PMID:20582225, GO:0007259=PMID:10918587, GO:0005524=GO_REF:0000037, GO:0048712=GO_REF:0000019, GO:0001938=GO_REF:0000019, GO:0021762=GO_REF:0000019, GO:0016023=GO_REF:0000039, GO:0016021=GO_REF:0000002, GO:0004713=PMID:11294897, GO:0043410=PMID:11294897, GO:0002009=GO_REF:0000019, GO:0090080=GO_REF:0000019} P22607 Fibroblast growth factor receptor 3 protein 20101216 {GO:0005515=IPI, GO:0003416=TAS, GO:0070307=IEA, GO:0045597=IEA, GO:0090263=IEA, GO:0050680=IEA, GO:0035988=TAS, GO:0005764=IEA, GO:0048678=IEA, GO:0061144=IEA, GO:0046777=IDA, GO:0007173=TAS, GO:0043552=TAS, GO:0002062=TAS, GO:0000165=IEA, GO:0031398=IEA, GO:0070374=IMP, GO:0017134=IDA, GO:0010518=IMP, GO:0018108=IDA, GO:0000122=IEA, GO:0048546=IEA, GO:0048640=ISS, GO:0045839=IEA, GO:0072148=IEA, GO:0001501=TAS, GO:0001958=TAS, GO:0008543=TAS, GO:0005887=IDA, GO:0045087=TAS, GO:0060349=TAS, GO:0060385=IEA, GO:0009898=IEA, GO:0005925=TAS, GO:0008286=TAS, GO:0048471=IEA, GO:0008284=IGI, GO:0005886=TAS, GO:0022010=IEA, GO:0005783=IEA, GO:0045879=IEA, GO:0002089=IEA, GO:0090102=IEA, GO:0035019=IEA, GO:0005007=IMP, GO:0048011=TAS, GO:0043066=IEA, GO:0043065=IEA, GO:0060113=IEA, GO:0048015=TAS, GO:0042517=IMP, GO:0042511=IMP, GO:0006915=IEA, GO:0042981=IMP, GO:0070977=ISS, GO:0007259=TAS, GO:0005524=IEA, GO:0048712=IEA, GO:0001938=IEA, GO:0021762=IEA, GO:0016023=IEA, GO:0016021=IEA, GO:0004713=IDA, GO:0043410=IMP, GO:0002009=IEA, GO:0090080=IEA} JAK-STAT cascade, MAPK cascade, alveolar secondary septum development, apoptotic process, axonogenesis involved in innervation, bone maturation, bone morphogenesis, central nervous system myelination, chondrocyte differentiation, chondrocyte proliferation, cochlea development, digestive tract morphogenesis, endochondral bone growth, endochondral ossification, epidermal growth factor receptor signaling pathway, epithelial cell fate commitment, fibroblast growth factor receptor signaling pathway, innate immune response, inner ear receptor cell differentiation, insulin receptor signaling pathway, lens fiber cell development, lens morphogenesis in camera-type eye, morphogenesis of an epithelium, negative regulation of apoptotic process, negative regulation of astrocyte differentiation, negative regulation of developmental growth, negative regulation of epithelial cell proliferation, negative regulation of mitosis, negative regulation of smoothened signaling pathway, negative regulation of transcription from RNA polymerase II promoter, neurotrophin TRK receptor signaling pathway, peptidyl-tyrosine phosphorylation, phosphatidylinositol-mediated signaling, positive regulation of ERK1 and ERK2 cascade, positive regulation of MAPK cascade, positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway, positive regulation of apoptotic process, positive regulation of canonical Wnt receptor signaling pathway, positive regulation of cell differentiation, positive regulation of cell proliferation, positive regulation of endothelial cell proliferation, positive regulation of phosphatidylinositol 3-kinase activity, positive regulation of phospholipase activity, positive regulation of protein ubiquitination, positive regulation of tyrosine phosphorylation of Stat1 protein, positive regulation of tyrosine phosphorylation of Stat3 protein, protein autophosphorylation, regulation of apoptotic process, response to axon injury, skeletal system development, somatic stem cell maintenance, substantia nigra development cytoplasmic membrane-bounded vesicle, endoplasmic reticulum, focal adhesion, integral to membrane, integral to plasma membrane, internal side of plasma membrane, lysosome, perinuclear region of cytoplasm, plasma membrane ATP binding, fibroblast growth factor binding, fibroblast growth factor-activated receptor activity, protein binding, protein tyrosine kinase activity Human UniProtKB:Q61851 FGFR4 HPA UniProtKB {GO:0008286=Reactome:REACT_498, GO:0008284=PMID:8663044, GO:2000188=GO_REF:0000024, GO:0005886=Reactome:REACT_147854, GO:0005783=PMID:20683963, GO:2000573=PMID:21653700, GO:0005634=GO_REF:0000052, GO:0001759=GO_REF:0000019, GO:0010715=PMID:20876804, GO:0061144=GO_REF:0000019, GO:0005737=GO_REF:0000052, GO:0046777=PMID:20798051, GO:0007173=Reactome:REACT_9417, GO:0005911=PMID:20798051, GO:0070857=PMID:20683963, GO:0070374=PMID:21653700, GO:0008201=PMID:18480409, GO:0005007=PMID:10525310, GO:0048011=Reactome:REACT_11061, GO:0017134=PMID:10525310, GO:0048015=Reactome:REACT_12464, GO:0005730=GO_REF:0000052, GO:0055062=GO_REF:0000024, GO:0005576=GO_REF:0000039, GO:0018108=PMID:18480409, GO:0042593=GO_REF:0000024, GO:0005524=GO_REF:0000037, GO:0045862=PMID:20798051, GO:0019216=GO_REF:0000024, GO:0048554=PMID:20798051, GO:0016477=PMID:20876804, GO:0008543=Reactome:REACT_9470, GO:0005887=PMID:20683963, GO:0045087=Reactome:REACT_6802, GO:0004713=Reactome:REACT_121299, GO:0016021=GO_REF:0000038, GO:0005768=GO_REF:0000039} P22455 Fibroblast growth factor receptor 4 protein 20101115 {GO:0008286=TAS, GO:0008284=IGI, GO:2000188=ISS, GO:0005886=TAS, GO:0005783=IDA, GO:2000573=IMP, GO:0005634=IDA, GO:0001759=IEA, GO:0010715=IMP, GO:0061144=IEA, GO:0005737=IDA, GO:0046777=IDA, GO:0007173=TAS, GO:0005911=IDA, GO:0070857=IMP, GO:0070374=IMP, GO:0008201=IDA, GO:0005007=IGI, GO:0048011=TAS, GO:0017134=IPI, GO:0048015=TAS, GO:0005730=IDA, GO:0055062=ISS, GO:0005576=IEA, GO:0018108=IDA, GO:0042593=ISS, GO:0005524=IEA, GO:0045862=IMP, GO:0019216=ISS, GO:0048554=IMP, GO:0016477=IMP, GO:0008543=TAS, GO:0005887=IDA, GO:0045087=TAS, GO:0004713=TAS, GO:0016021=IEA, GO:0005768=IEA} alveolar secondary septum development, cell migration, epidermal growth factor receptor signaling pathway, fibroblast growth factor receptor signaling pathway, glucose homeostasis, innate immune response, insulin receptor signaling pathway, neurotrophin TRK receptor signaling pathway, organ induction, peptidyl-tyrosine phosphorylation, phosphate ion homeostasis, phosphatidylinositol-mediated signaling, positive regulation of DNA biosynthetic process, positive regulation of ERK1 and ERK2 cascade, positive regulation of cell proliferation, positive regulation of metalloenzyme activity, positive regulation of proteolysis, protein autophosphorylation, regulation of bile acid biosynthetic process, regulation of cholesterol homeostasis, regulation of extracellular matrix disassembly, regulation of lipid metabolic process cell-cell junction, cytoplasm, endoplasmic reticulum, endosome, extracellular region, integral to membrane, integral to plasma membrane, nucleolus, nucleus, plasma membrane ATP binding, fibroblast growth factor binding, fibroblast growth factor-activated receptor activity, heparin binding, protein tyrosine kinase activity Human FGFRL1 GOC UniProtKB {GO:0005007=PMID:12813049, GO:0001501=GO_REF:0000019, GO:0008285=GO_REF:0000019, GO:0005886=PMID:12813049, GO:0008543=PMID:12813049, GO:0017134=GO_REF:0000019, GO:0060412=GO_REF:0000019, GO:0060539=GO_REF:0000019, GO:0016021=GO_REF:0000037, GO:0003179=GO_REF:0000019, GO:0008201=PMID:12813049, GO:0001558=GO_REF:0000029} Q8N441 Fibroblast growth factor receptor-like 1 protein 20130413 {GO:0005007=IDA, GO:0001501=IEA, GO:0008285=IEA, GO:0005886=IDA, GO:0008543=IDA, GO:0017134=IEA, GO:0060412=IEA, GO:0060539=IEA, GO:0016021=IEA, GO:0003179=IEA, GO:0008201=IDA, GO:0001558=NAS} diaphragm development, fibroblast growth factor receptor signaling pathway, heart valve morphogenesis, negative regulation of cell proliferation, regulation of cell growth, skeletal system development, ventricular septum morphogenesis integral to membrane, plasma membrane fibroblast growth factor binding, fibroblast growth factor-activated receptor activity, heparin binding Human FGG BHF-UCL UniProtKB {GO:0051258=GO_REF:0000002, GO:0043499=PMID:6777381, GO:0005886=Reactome:REACT_726, GO:0005102=GO_REF:0000002, GO:0005577=GO_REF:0000002, GO:0030168=Reactome:REACT_798, GO:0072562=GO_REF:0000019, GO:0005576=Reactome:REACT_23931, GO:0005615=PMID:6777381, GO:0046872=GO_REF:0000037, GO:0051592=PMID:6777381, GO:0007165=GO_REF:0000002, GO:0007596=Reactome:REACT_2051, GO:0002576=Reactome:REACT_318, GO:0031091=PMID:6777381, GO:0031093=Reactome:REACT_21351, GO:0030674=GO_REF:0000002, GO:0005938=GO_REF:0000019, GO:0009897=PMID:6777381} P02679 Fibrinogen gamma chain protein 20081001 {GO:0051258=IEA, GO:0043499=IDA, GO:0005886=TAS, GO:0005102=IEA, GO:0005577=IEA, GO:0030168=TAS, GO:0072562=IEA, GO:0005576=TAS, GO:0005615=IDA, GO:0046872=IEA, GO:0051592=IDA, GO:0007165=IEA, GO:0007596=TAS, GO:0002576=TAS, GO:0031091=IDA, GO:0031093=TAS, GO:0030674=IEA, GO:0005938=IEA, GO:0009897=IDA} blood coagulation, platelet activation, platelet degranulation, protein polymerization, response to calcium ion, signal transduction blood microparticle, cell cortex, external side of plasma membrane, extracellular region, extracellular space, fibrinogen complex, plasma membrane, platelet alpha granule, platelet alpha granule lumen eukaryotic cell surface binding, metal ion binding, protein binding, bridging, receptor binding Human FGL1 PINC UniProtKB {GO:0035634=GO_REF:0000019, GO:0005577=PMID:8390249} Q08830 Fibrinogen-like protein 1 protein 20030904 {GO:0035634=IEA, GO:0005577=TAS} response to stilbenoid fibrinogen complex Human FGR ENSEMBL UniProtKB {GO:0005515=PMID:22939624, GO:0045859=GO_REF:0000019, GO:0005886=GO_REF:0000024, GO:0050830=GO_REF:0000019, GO:0008360=GO_REF:0000019, GO:0005743=GO_REF:0000039, GO:0050715=GO_REF:0000019, GO:0015629=GO_REF:0000019, GO:0005829=GO_REF:0000019, GO:0050764=GO_REF:0000019, GO:0005758=GO_REF:0000039, GO:0046777=PMID:8327512, GO:0043552=PMID:10739672, GO:0005856=PMID:8603737, GO:0034987=GO_REF:0000019, GO:0030335=GO_REF:0000019, GO:0034988=PMID:8327512, GO:0019901=GO_REF:0000019, GO:0014068=PMID:10739672, GO:0018108=GO_REF:0000019, GO:0032587=GO_REF:0000019, GO:0009615=PMID:3003578, GO:0005524=GO_REF:0000002, GO:0043306=GO_REF:0000019, GO:0002768=PMID:8327512, GO:0007596=Reactome:REACT_604, GO:0007229=GO_REF:0000019, GO:0045087=Reactome:REACT_6802, GO:0045088=GO_REF:0000019, GO:0006468=PMID:2995972, GO:0001784=GO_REF:0000019, GO:0004713=PMID:7519620, GO:0038096=Reactome:REACT_160123, GO:0004715=GO_REF:0000019} Q5TGY6 Tyrosine-protein kinase Fgr protein 20130413 {GO:0005515=IPI, GO:0045859=IEA, GO:0005886=ISS, GO:0050830=IEA, GO:0008360=IEA, GO:0005743=IEA, GO:0050715=IEA, GO:0015629=IEA, GO:0005829=IEA, GO:0050764=IEA, GO:0005758=IEA, GO:0046777=IDA, GO:0043552=IMP, GO:0005856=IDA, GO:0034987=IEA, GO:0030335=IEA, GO:0034988=IDA, GO:0019901=IEA, GO:0014068=IMP, GO:0018108=IEA, GO:0032587=IEA, GO:0009615=TAS, GO:0005524=IEA, GO:0043306=IEA, GO:0002768=TAS, GO:0007596=TAS, GO:0007229=IEA, GO:0045087=TAS, GO:0045088=IEA, GO:0006468=TAS, GO:0001784=IEA, GO:0004713=IDA, GO:0038096=TAS, GO:0004715=IEA} Fc-gamma receptor signaling pathway involved in phagocytosis, blood coagulation, defense response to Gram-positive bacterium, immune response-regulating cell surface receptor signaling pathway, innate immune response, integrin-mediated signaling pathway, peptidyl-tyrosine phosphorylation, positive regulation of cell migration, positive regulation of cytokine secretion, positive regulation of mast cell degranulation, positive regulation of phosphatidylinositol 3-kinase activity, positive regulation of phosphatidylinositol 3-kinase cascade, protein autophosphorylation, protein phosphorylation, regulation of cell shape, regulation of innate immune response, regulation of phagocytosis, regulation of protein kinase activity, response to virus actin cytoskeleton, cytoskeleton, cytosol, mitochondrial inner membrane, mitochondrial intermembrane space, plasma membrane, ruffle membrane ATP binding, Fc-gamma receptor I complex binding, immunoglobulin receptor binding, non-membrane spanning protein tyrosine kinase activity, phosphotyrosine binding, protein binding, protein kinase binding, protein tyrosine kinase activity Human Ensembl:ENSMUSP00000030693 FH Reactome UniProtKB {GO:0005739=PMID:8200987, GO:0005737=PMID:8200987, GO:0004333=Reactome:REACT_21360, GO:0006099=Reactome:REACT_1785, GO:0048873=GO_REF:0000019, GO:0006106=GO_REF:0000002, GO:0005759=Reactome:REACT_21360, GO:0044281=Reactome:REACT_111217, GO:0045239=GO_REF:0000002} P07954 Fumarate hydratase, mitochondrial protein 20091226 {GO:0005739=TAS, GO:0005737=TAS, GO:0004333=EXP, GO:0006099=TAS, GO:0048873=IEA, GO:0006106=IEA, GO:0005759=TAS, GO:0044281=TAS, GO:0045239=IEA} fumarate metabolic process, homeostasis of number of cells within a tissue, small molecule metabolic process, tricarboxylic acid cycle cytoplasm, mitochondrial matrix, mitochondrion, tricarboxylic acid cycle enzyme complex fumarate hydratase activity Human FHIT HPA UniProtKB {GO:0005515=PMID:18319262, GO:0006355=GO_REF:0000037, GO:0047710=PMID:9323207, GO:0032435=PMID:15313915, GO:0003824=PMID:8598045, GO:0006351=GO_REF:0000037, GO:0043231=GO_REF:0000052, GO:0042802=PMID:16189514, GO:0005829=PMID:15313915, GO:0006260=GO_REF:0000019, GO:0005737=GO_REF:0000052, GO:0000166=GO_REF:0000037, GO:0072332=PMID:15313915, GO:0016787=PMID:8794732, GO:0009117=PMID:8794732, GO:0031625=PMID:15313915, GO:0006163=PMID:9323207} P49789 Bis(5'-adenosyl)-triphosphatase protein 20100326 {GO:0005515=IPI, GO:0006355=IEA, GO:0047710=IDA, GO:0032435=IMP, GO:0003824=TAS, GO:0006351=IEA, GO:0043231=IDA, GO:0042802=IPI, GO:0005829=IDA, GO:0006260=IEA, GO:0005737=IDA, GO:0000166=IEA, GO:0072332=IMP, GO:0016787=IDA, GO:0009117=TAS, GO:0031625=IPI, GO:0006163=IDA} DNA replication, intrinsic apoptotic signaling pathway by p53 class mediator, negative regulation of proteasomal ubiquitin-dependent protein catabolic process, nucleotide metabolic process, purine nucleotide metabolic process, regulation of transcription, DNA-dependent, transcription, DNA-dependent cytoplasm, cytosol, intracellular membrane-bounded organelle bis(5'-adenosyl)-triphosphatase activity, catalytic activity, hydrolase activity, identical protein binding, nucleotide binding, protein binding, ubiquitin protein ligase binding Human FHL1 HPA UniProtKB {GO:0005515=PMID:19401155, GO:0030308=PMID:21702045, GO:0005886=GO_REF:0000052, GO:0043268=PMID:18281375, GO:0005634=PMID:21702045, GO:2000134=PMID:21702045, GO:0030154=GO_REF:0000037, GO:0005829=GO_REF:0000039, GO:0003674=GO_REF:0000015, GO:0005737=GO_REF:0000052, GO:0007517=PMID:7626119, GO:0010972=PMID:21702045, GO:0009887=PMID:7626119, GO:0008270=GO_REF:0000002, GO:0003254=PMID:18281375} Q5JXI8 Four and a half LIM domains protein 1 protein 20090616 {GO:0005515=IPI, GO:0030308=IDA, GO:0005886=IDA, GO:0043268=IDA, GO:0005634=IDA, GO:2000134=IDA, GO:0030154=IEA, GO:0005829=IEA, GO:0003674=ND, GO:0005737=IDA, GO:0007517=NAS, GO:0010972=IDA, GO:0009887=NAS, GO:0008270=IEA, GO:0003254=IDA} cell differentiation, muscle organ development, negative regulation of G1/S transition of mitotic cell cycle, negative regulation of G2/M transition of mitotic cell cycle, negative regulation of cell growth, organ morphogenesis, positive regulation of potassium ion transport, regulation of membrane depolarization cytoplasm, cytosol, nucleus, plasma membrane molecular_function, protein binding, zinc ion binding Human FHL2 InterPro UniProtKB {GO:0005515=PMID:19608030, GO:0030018=GO_REF:0000019, GO:0005634=GO_REF:0000052, GO:0050681=PMID:15572661, GO:0044281=Reactome:REACT_111217, GO:0015629=GO_REF:0000052, GO:0042802=PMID:18255255, GO:0009725=PMID:17975004, GO:0044255=Reactome:REACT_22279, GO:0043066=PMID:15692560, GO:0006357=GO_REF:0000019, GO:0003713=PMID:15572661, GO:0000122=PMID:15692560, GO:0031430=GO_REF:0000019, GO:0006351=GO_REF:0000037, GO:0001649=GO_REF:0000019, GO:0060347=GO_REF:0000019, GO:0055015=GO_REF:0000019, GO:0008270=GO_REF:0000002, GO:0005654=Reactome:REACT_116040, GO:0055014=GO_REF:0000019, GO:0045893=PMID:15572661, GO:0045892=GO_REF:0000019, GO:0005925=GO_REF:0000052, GO:0030521=PMID:15572661, GO:0008134=PMID:15692560} Q5TM15 Splice variant of four and a half LIM domain protein 2 protein 20130413 {GO:0005515=IPI, GO:0030018=IEA, GO:0005634=IDA, GO:0050681=NAS, GO:0044281=TAS, GO:0015629=IDA, GO:0042802=IPI, GO:0009725=IMP, GO:0044255=TAS, GO:0043066=IDA, GO:0006357=IEA, GO:0003713=NAS, GO:0000122=IDA, GO:0031430=IEA, GO:0006351=IEA, GO:0001649=IEA, GO:0060347=IEA, GO:0055015=IEA, GO:0008270=IEA, GO:0005654=TAS, GO:0055014=IEA, GO:0045893=NAS, GO:0045892=IEA, GO:0005925=IDA, GO:0030521=NAS, GO:0008134=IPI} androgen receptor signaling pathway, atrial cardiac muscle cell development, cellular lipid metabolic process, heart trabecula formation, negative regulation of apoptotic process, negative regulation of transcription from RNA polymerase II promoter, negative regulation of transcription, DNA-dependent, osteoblast differentiation, positive regulation of transcription, DNA-dependent, regulation of transcription from RNA polymerase II promoter, response to hormone stimulus, small molecule metabolic process, transcription, DNA-dependent, ventricular cardiac muscle cell development M band, Z disc, actin cytoskeleton, focal adhesion, nucleoplasm, nucleus androgen receptor binding, identical protein binding, protein binding, transcription coactivator activity, transcription factor binding, zinc ion binding Human InterPro:IPR001781 FHL3 PINC UniProtKB {GO:0030018=GO_REF:0000019, GO:0001725=GO_REF:0000019, GO:0007517=PMID:10049693, GO:0030036=GO_REF:0000019, GO:0005634=GO_REF:0000019, GO:0003779=GO_REF:0000019, GO:0008270=GO_REF:0000002} Q13643 Four and a half LIM domains protein 3 protein 20030904 {GO:0030018=IEA, GO:0001725=IEA, GO:0007517=TAS, GO:0030036=IEA, GO:0005634=IEA, GO:0003779=IEA, GO:0008270=IEA} actin cytoskeleton organization, muscle organ development Z disc, nucleus, stress fiber actin binding, zinc ion binding Human FHL5 UniProtKB UniProtKB {GO:0045944=GO_REF:0000019, GO:0003713=GO_REF:0000019, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002} Q5TD97 Four and a half LIM domains protein 5 protein 20130413 {GO:0045944=IEA, GO:0003713=IEA, GO:0005634=IEA, GO:0008270=IEA} positive regulation of transcription from RNA polymerase II promoter nucleus transcription coactivator activity, zinc ion binding Human UniProtKB-SubCell:SL-0191 FHOD1 HPA UniProtKB {GO:0005515=PMID:15095401, GO:0001725=PMID:15095401, GO:0005737=GO_REF:0000052, GO:0032059=GO_REF:0000039, GO:0030036=GO_REF:0000002, GO:0045944=PMID:15095401, GO:0051496=PMID:15095401, GO:0005634=PMID:15095401, GO:0003779=GO_REF:0000037} Q9Y613 FH1/FH2 domain-containing protein 1 protein 20101115 {GO:0005515=IPI, GO:0001725=IDA, GO:0005737=IDA, GO:0032059=IEA, GO:0030036=IEA, GO:0045944=IDA, GO:0051496=IDA, GO:0005634=IDA, GO:0003779=IEA} actin cytoskeleton organization, positive regulation of stress fiber assembly, positive regulation of transcription from RNA polymerase II promoter bleb, cytoplasm, nucleus, stress fiber actin binding, protein binding Human FHOD3 HPA UniProtKB {GO:0005515=PMID:21149568, GO:0005737=GO_REF:0000052, GO:0030018=GO_REF:0000039, GO:0030036=GO_REF:0000002, GO:0030837=GO_REF:0000019, GO:0005730=GO_REF:0000052, GO:0045214=GO_REF:0000019, GO:0005634=GO_REF:0000052, GO:0003779=GO_REF:0000037, GO:0005856=GO_REF:0000039} Q2V2M9 FH1/FH2 domain-containing protein 3 protein 20110516 {GO:0005515=IPI, GO:0005737=IDA, GO:0030018=IEA, GO:0030036=IEA, GO:0030837=IEA, GO:0005730=IDA, GO:0045214=IEA, GO:0005634=IDA, GO:0003779=IEA, GO:0005856=IEA} actin cytoskeleton organization, negative regulation of actin filament polymerization, sarcomere organization Z disc, cytoplasm, cytoskeleton, nucleolus, nucleus actin binding, protein binding Human FIBCD1 UniProtKB UniProtKB {GO:0008061=PMID:19710473, GO:0016020=PMID:19710473, GO:0016021=GO_REF:0000037, GO:0046872=GO_REF:0000037} Q8N539 Fibrinogen C domain-containing protein 1 protein 20100126 {GO:0008061=IDA, GO:0016020=IDA, GO:0016021=IEA, GO:0046872=IEA} integral to membrane, membrane chitin binding, metal ion binding Human FIBP MGI UniProtKB {GO:0005739=PMID:9806903, GO:0016020=PMID:9806903, GO:0008543=PMID:9806903, GO:0017134=PMID:9806903, GO:0005634=PMID:9806903, GO:0012505=GO_REF:0000039} O43427 Acidic fibroblast growth factor intracellular-binding protein protein 20091019 {GO:0005739=TAS, GO:0016020=IDA, GO:0008543=TAS, GO:0017134=IPI, GO:0005634=IDA, GO:0012505=IEA} fibroblast growth factor receptor signaling pathway endomembrane system, membrane, mitochondrion, nucleus fibroblast growth factor binding Human UniProtKB:P05230 FICD UniProtKB UniProtKB {GO:0018117=PMID:22266942, GO:0034259=PMID:19362538, GO:0016021=GO_REF:0000037, GO:0005524=GO_REF:0000037, GO:0070733=PMID:22266942} Q9BVA6 Adenosine monophosphate-protein transferase FICD protein 20120503 {GO:0018117=IDA, GO:0034259=TAS, GO:0016021=IEA, GO:0005524=IEA, GO:0070733=IDA} negative regulation of Rho GTPase activity, protein adenylylation integral to membrane ATP binding, protein adenylyltransferase activity Human FIG4 GOC UniProtKB {GO:0005515=PMID:17556371, GO:0008219=GO_REF:0000037, GO:0006661=Reactome:REACT_120918, GO:0043813=Reactome:REACT_121182, GO:0036092=Reactome:REACT_121182, GO:0043812=GO_REF:0000019, GO:0046488=GO_REF:0000019, GO:0044281=Reactome:REACT_111217, GO:0034593=GO_REF:0000019, GO:0032288=GO_REF:0000019, GO:0042578=GO_REF:0000002, GO:0000139=Reactome:REACT_121149, GO:0048666=GO_REF:0000019, GO:0031901=Reactome:REACT_121095, GO:0004438=GO_REF:0000019, GO:0031902=Reactome:REACT_121182, GO:0010976=GO_REF:0000019, GO:0043473=GO_REF:0000019, GO:0007626=GO_REF:0000019, GO:0007033=GO_REF:0000019, GO:0006644=Reactome:REACT_121175, GO:0010008=PMID:17556371, GO:0031642=GO_REF:0000019} Q92562 Polyphosphoinositide phosphatase protein 20130413 {GO:0005515=IPI, GO:0008219=IEA, GO:0006661=TAS, GO:0043813=TAS, GO:0036092=TAS, GO:0043812=IEA, GO:0046488=IEA, GO:0044281=TAS, GO:0034593=IEA, GO:0032288=IEA, GO:0042578=IEA, GO:0000139=TAS, GO:0048666=IEA, GO:0031901=TAS, GO:0004438=IEA, GO:0031902=TAS, GO:0010976=IEA, GO:0043473=IEA, GO:0007626=IEA, GO:0007033=IEA, GO:0006644=TAS, GO:0010008=IDA, GO:0031642=IEA} cell death, locomotory behavior, myelin assembly, negative regulation of myelination, neuron development, phosphatidylinositol biosynthetic process, phosphatidylinositol metabolic process, phosphatidylinositol-3-phosphate biosynthetic process, phospholipid metabolic process, pigmentation, positive regulation of neuron projection development, small molecule metabolic process, vacuole organization Golgi membrane, early endosome membrane, endosome membrane, late endosome membrane phosphatidylinositol bisphosphate phosphatase activity, phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity, phosphatidylinositol-3-phosphatase activity, phosphatidylinositol-4-phosphate phosphatase activity, phosphoric ester hydrolase activity, protein binding Human FIGF GOC UniProtKB {GO:0048010=Reactome:REACT_12529, GO:0008284=GO_REF:0000019, GO:0008283=GO_REF:0000019, GO:0030168=Reactome:REACT_798, GO:0005576=Reactome:REACT_21351, GO:0060754=PMID:19275959, GO:0001525=GO_REF:0000037, GO:0005161=PMID:9479493, GO:0005615=GO_REF:0000019, GO:0042056=PMID:19275959, GO:0030154=GO_REF:0000037, GO:0042803=GO_REF:0000019, GO:0050918=PMID:19275959, GO:0050930=PMID:19275959, GO:0016020=GO_REF:0000002, GO:0007596=Reactome:REACT_604, GO:0002576=Reactome:REACT_318, GO:0043185=GO_REF:0000019, GO:0031093=Reactome:REACT_21351, GO:0051781=GO_REF:0000037, GO:0005172=PMID:9435229, GO:0008083=GO_REF:0000019} O43915 Vascular endothelial growth factor D protein 20130413 {GO:0048010=TAS, GO:0008284=IEA, GO:0008283=IEA, GO:0030168=TAS, GO:0005576=TAS, GO:0060754=IDA, GO:0001525=IEA, GO:0005161=TAS, GO:0005615=IEA, GO:0042056=IDA, GO:0030154=IEA, GO:0042803=IEA, GO:0050918=IDA, GO:0050930=IDA, GO:0016020=IEA, GO:0007596=TAS, GO:0002576=TAS, GO:0043185=IEA, GO:0031093=TAS, GO:0051781=IEA, GO:0005172=IPI, GO:0008083=IEA} angiogenesis, blood coagulation, cell differentiation, cell proliferation, induction of positive chemotaxis, platelet activation, platelet degranulation, positive chemotaxis, positive regulation of cell division, positive regulation of cell proliferation, positive regulation of mast cell chemotaxis, vascular endothelial growth factor receptor signaling pathway extracellular region, extracellular space, membrane, platelet alpha granule lumen chemoattractant activity, growth factor activity, platelet-derived growth factor receptor binding, protein homodimerization activity, vascular endothelial growth factor receptor 3 binding, vascular endothelial growth factor receptor binding Human FIGN UniProtKB UniProtKB {GO:0017111=GO_REF:0000002, GO:0008022=GO_REF:0000019, GO:0005524=GO_REF:0000037, GO:0016363=GO_REF:0000024} Q5HY92 Fidgetin protein 20090922 {GO:0017111=IEA, GO:0008022=IEA, GO:0005524=IEA, GO:0016363=ISS} nuclear matrix ATP binding, nucleoside-triphosphatase activity, protein C-terminus binding Human UniProtKB:Q9ERZ6 FIGNL1 UniProtKB UniProtKB {GO:0017111=GO_REF:0000002, GO:0043066=GO_REF:0000024, GO:0005737=GO_REF:0000024, GO:0046034=GO_REF:0000024, GO:0000287=GO_REF:0000024, GO:0016787=GO_REF:0000024, GO:0033687=GO_REF:0000024, GO:0051726=GO_REF:0000024, GO:0005634=GO_REF:0000024, GO:0005524=GO_REF:0000037, GO:0001649=GO_REF:0000024} Q6PIW4 Fidgetin-like protein 1 protein 20110302 {GO:0017111=IEA, GO:0043066=ISS, GO:0005737=ISS, GO:0046034=ISS, GO:0000287=ISS, GO:0016787=ISS, GO:0033687=ISS, GO:0051726=ISS, GO:0005634=ISS, GO:0005524=IEA, GO:0001649=ISS} ATP metabolic process, negative regulation of apoptotic process, osteoblast differentiation, osteoblast proliferation, regulation of cell cycle cytoplasm, nucleus ATP binding, hydrolase activity, magnesium ion binding, nucleoside-triphosphatase activity Human UniProtKB:Q8BPY9 FILIP1 null null {} null null null null {} null null null FILIP1L UniProtKB UniProtKB {GO:0008150=GO_REF:0000015, GO:0003674=GO_REF:0000015, GO:0005737=GO_REF:0000039, GO:0016020=GO_REF:0000039, GO:0005634=GO_REF:0000039, GO:0016459=GO_REF:0000029} Q4L180 Filamin A-interacting protein 1-like protein 20061026 {GO:0008150=ND, GO:0003674=ND, GO:0005737=IEA, GO:0016020=IEA, GO:0005634=IEA, GO:0016459=NAS} biological_process cytoplasm, membrane, myosin complex, nucleus molecular_function Human FIP1L1 HPA UniProtKB {GO:0006397=GO_REF:0000037, GO:0003723=GO_REF:0000037, GO:0005730=GO_REF:0000052, GO:0005847=GO_REF:0000019, GO:0005634=GO_REF:0000052} Q6UN15 Pre-mRNA 3'-end-processing factor FIP1 protein 20111111 {GO:0006397=IEA, GO:0003723=IEA, GO:0005730=IDA, GO:0005847=IEA, GO:0005634=IDA} mRNA processing mRNA cleavage and polyadenylation specificity factor complex, nucleolus, nucleus RNA binding NOT Human FIS1 HPA UniProtKB {GO:0005515=PMID:21183955, GO:0035584=PMID:21183955, GO:0010821=PMID:21149567, GO:0000266=PMID:18845145, GO:0000422=PMID:18515060, GO:0005102=PMID:20178365, GO:0006915=PMID:16118244, GO:0001836=PMID:19864424, GO:0043653=PMID:17545159, GO:0007204=PMID:21183955, GO:0043280=PMID:21183955, GO:0005739=GO_REF:0000052, GO:0043234=PMID:20826455, GO:0070584=PMID:21149567, GO:0051561=PMID:21183955, GO:0051260=PMID:18845145, GO:0031307=PMID:18845145, GO:0005779=PMID:17408615, GO:0032471=PMID:21183955, GO:0005777=PMID:14561759, GO:0016559=PMID:20826455} Q9Y3D6 Mitochondrial fission 1 protein protein 20090616 {GO:0005515=IPI, GO:0035584=IMP, GO:0010821=IMP, GO:0000266=IDA, GO:0000422=IDA, GO:0005102=IPI, GO:0006915=IDA, GO:0001836=IMP, GO:0043653=IDA, GO:0007204=IMP, GO:0043280=IMP, GO:0005739=IDA, GO:0043234=IDA, GO:0070584=IMP, GO:0051561=IMP, GO:0051260=IMP, GO:0031307=NAS, GO:0005779=IDA, GO:0032471=IMP, GO:0005777=ISS, GO:0016559=IMP} apoptotic process, calcium-mediated signaling using intracellular calcium source, elevation of cytosolic calcium ion concentration, elevation of mitochondrial calcium ion concentration, mitochondrial fission, mitochondrial fragmentation involved in apoptotic process, mitochondrion degradation, mitochondrion morphogenesis, peroxisome fission, positive regulation of cysteine-type endopeptidase activity involved in apoptotic process, protein homooligomerization, reduction of endoplasmic reticulum calcium ion concentration, regulation of mitochondrion organization, release of cytochrome c from mitochondria integral to mitochondrial outer membrane, integral to peroxisomal membrane, mitochondrion, peroxisome, protein complex protein binding, receptor binding Human FITM1 BHF-UCL UniProtKB {GO:0003674=GO_REF:0000015, GO:0010890=PMID:18160536, GO:0005789=PMID:18160536, GO:0030176=GO_REF:0000019, GO:0034389=PMID:18160536} A5D6W6 Fat storage-inducing transmembrane protein 1 protein 20100303 {GO:0003674=ND, GO:0010890=ISS, GO:0005789=ISS, GO:0030176=IEA, GO:0034389=ISS} lipid particle organization, positive regulation of sequestering of triglyceride endoplasmic reticulum membrane, integral to endoplasmic reticulum membrane molecular_function Human FITM2 BHF-UCL UniProtKB {GO:0005739=GO_REF:0000019, GO:0003674=GO_REF:0000015, GO:0010890=PMID:18160536, GO:0022604=PMID:21834987, GO:0007010=PMID:21834987, GO:0005789=PMID:18160536, GO:0030176=GO_REF:0000024, GO:0035356=PMID:18160536, GO:0010866=PMID:18160536, GO:0034389=PMID:18160536} Q8N6M3 Fat storage-inducing transmembrane protein 2 protein 20100303 {GO:0005739=IEA, GO:0003674=ND, GO:0010890=ISS, GO:0022604=IMP, GO:0007010=IMP, GO:0005789=ISS, GO:0030176=ISS, GO:0035356=ISS, GO:0010866=ISS, GO:0034389=ISS} cellular triglyceride homeostasis, cytoskeleton organization, lipid particle organization, positive regulation of sequestering of triglyceride, regulation of cell morphogenesis, regulation of triglyceride biosynthetic process endoplasmic reticulum membrane, integral to endoplasmic reticulum membrane, mitochondrion molecular_function Human FIZ1 UniProtKB UniProtKB {GO:0005737=GO_REF:0000024, GO:0006355=GO_REF:0000037, GO:0019901=GO_REF:0000024, GO:0005102=GO_REF:0000024, GO:0005634=GO_REF:0000024, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0006351=GO_REF:0000037} Q96SL8 Flt3-interacting zinc finger protein 1 protein 20050413 {GO:0005737=ISS, GO:0006355=IEA, GO:0019901=ISS, GO:0005102=ISS, GO:0005634=ISS, GO:0008270=IEA, GO:0003676=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent cytoplasm, nucleus nucleic acid binding, protein kinase binding, receptor binding, zinc ion binding Human UniProtKB:Q9WTJ4 FJX1 ENSEMBL UniProtKB {GO:0005615=GO_REF:0000019} Q86VR8 Four-jointed box protein 1 protein 20130413 {GO:0005615=IEA} extracellular space Human Ensembl:ENSMUSP00000097270 FKBP10 InterPro UniProtKB {GO:0000413=GO_REF:0000033, GO:0016020=GO_REF:0000033, GO:0006457=GO_REF:0000002, GO:0018208=GO_REF:0000033, GO:0005509=GO_REF:0000002, GO:0003755=GO_REF:0000033, GO:0005528=GO_REF:0000033, GO:0005788=GO_REF:0000039} Q9H6J3 Peptidyl-prolyl cis-trans isomerase FKBP10 protein 20130413 {GO:0000413=IBA, GO:0016020=IBA, GO:0006457=IEA, GO:0018208=IBA, GO:0005509=IEA, GO:0003755=IBA, GO:0005528=IBA, GO:0005788=IEA} peptidyl-proline modification, protein folding, protein peptidyl-prolyl isomerization endoplasmic reticulum lumen, membrane FK506 binding, calcium ion binding, peptidyl-prolyl cis-trans isomerase activity Human InterPro:IPR001179 FKBP11 GOC UniProtKB {GO:0000413=GO_REF:0000033, GO:0016020=GO_REF:0000033, GO:0006457=GO_REF:0000037, GO:0018208=GO_REF:0000033, GO:0003755=GO_REF:0000033, GO:0005528=GO_REF:0000033, GO:0016021=GO_REF:0000037} Q9NYL4 Peptidyl-prolyl cis-trans isomerase FKBP11 protein 20130413 {GO:0000413=IBA, GO:0016020=IBA, GO:0006457=IEA, GO:0018208=IBA, GO:0003755=IBA, GO:0005528=IBA, GO:0016021=IEA} peptidyl-proline modification, protein folding, protein peptidyl-prolyl isomerization integral to membrane, membrane FK506 binding, peptidyl-prolyl cis-trans isomerase activity Human PANTHER:PTN000054102 FKBP14 GOC UniProtKB {GO:0000413=GO_REF:0000033, GO:0016020=GO_REF:0000033, GO:0006457=GO_REF:0000037, GO:0018208=GO_REF:0000033, GO:0005509=GO_REF:0000002, GO:0003755=GO_REF:0000033, GO:0005788=Reactome:REACT_115587, GO:0005528=GO_REF:0000033, GO:0006987=Reactome:REACT_18368, GO:0044267=Reactome:REACT_17015, GO:0030968=Reactome:REACT_18356} Q9NWM8 Peptidyl-prolyl cis-trans isomerase FKBP14 protein 20130413 {GO:0000413=IBA, GO:0016020=IBA, GO:0006457=IEA, GO:0018208=IBA, GO:0005509=IEA, GO:0003755=IBA, GO:0005788=TAS, GO:0005528=IBA, GO:0006987=TAS, GO:0044267=TAS, GO:0030968=TAS} activation of signaling protein activity involved in unfolded protein response, cellular protein metabolic process, endoplasmic reticulum unfolded protein response, peptidyl-proline modification, protein folding, protein peptidyl-prolyl isomerization endoplasmic reticulum lumen, membrane FK506 binding, calcium ion binding, peptidyl-prolyl cis-trans isomerase activity Human PANTHER:PTN000054102 FKBP15 UniProtKB UniProtKB {GO:0030424=GO_REF:0000039, GO:0006457=GO_REF:0000002, GO:0010923=PMID:19389623, GO:0005884=GO_REF:0000019, GO:0003779=GO_REF:0000037, GO:0005769=GO_REF:0000039, GO:0030426=GO_REF:0000019, GO:0006897=GO_REF:0000037} Q5T1M5 FK506-binding protein 15 protein 20111103 {GO:0030424=IEA, GO:0006457=IEA, GO:0010923=IDA, GO:0005884=IEA, GO:0003779=IEA, GO:0005769=IEA, GO:0030426=IEA, GO:0006897=IEA} endocytosis, negative regulation of phosphatase activity, protein folding actin filament, axon, early endosome, growth cone actin binding Human FKBP1A UniProtKB UniProtKB {GO:0000413=PMID:2477715, GO:0005515=PMID:10358090, GO:0030424=GO_REF:0000033, GO:0055010=GO_REF:0000024, GO:0046332=PMID:16720724, GO:0022417=PMID:11322937, GO:0032092=PMID:18346205, GO:0005829=PMID:1701173, GO:0042026=PMID:11322937, GO:0005737=PMID:12443530, GO:0006458=PMID:11322937, GO:0006457=GO_REF:0000038, GO:0048185=PMID:16720724, GO:0060314=PMID:7592869, GO:0060315=PMID:12443530, GO:0031398=PMID:16720724, GO:0005024=PMID:11322937, GO:0007179=Reactome:REACT_120850, GO:0043206=PMID:18346205, GO:0004871=PMID:12761501, GO:0051280=PMID:12443530, GO:0043123=PMID:12761501, GO:0014802=PMID:1374404, GO:0003755=GO_REF:0000038, GO:0005528=PMID:17962721, GO:0033017=GO_REF:0000033, GO:0005160=PMID:7518616, GO:0032925=PMID:16720724, GO:0034205=PMID:18346205, GO:0005527=PMID:17962721, GO:0060347=GO_REF:0000024, GO:0007183=PMID:16720724, GO:0003007=GO_REF:0000024, GO:0042110=PMID:1696686, GO:0016020=PMID:12443530, GO:0034713=PMID:7518616, GO:0019855=PMID:12443530, GO:0018208=GO_REF:0000033, GO:0032513=PMID:7592869, GO:0050776=PMID:2477715, GO:0005219=PMID:11322937} Q5W0X3 Peptidyl-prolyl cis-trans isomerase protein 20130413 {GO:0000413=IDA, GO:0005515=IPI, GO:0030424=IBA, GO:0055010=ISS, GO:0046332=IPI, GO:0022417=TAS, GO:0032092=IDA, GO:0005829=IDA, GO:0042026=TAS, GO:0005737=IDA, GO:0006458=TAS, GO:0006457=IEA, GO:0048185=IPI, GO:0060314=IDA, GO:0060315=IDA, GO:0031398=IDA, GO:0005024=TAS, GO:0007179=TAS, GO:0043206=IDA, GO:0004871=IMP, GO:0051280=IDA, GO:0043123=IMP, GO:0014802=ISS, GO:0003755=IEA, GO:0005528=NAS, GO:0033017=IBA, GO:0005160=ISS, GO:0032925=IDA, GO:0034205=IDA, GO:0005527=NAS, GO:0060347=ISS, GO:0007183=IDA, GO:0003007=ISS, GO:0042110=NAS, GO:0016020=IDA, GO:0034713=ISS, GO:0019855=IDA, GO:0018208=IBA, GO:0032513=IDA, GO:0050776=IMP, GO:0005219=TAS} 'de novo' protein folding, SMAD protein complex assembly, T cell activation, beta-amyloid formation, extracellular fibril organization, heart morphogenesis, heart trabecula formation, negative regulation of protein phosphatase type 2B activity, negative regulation of release of sequestered calcium ion into cytosol, negative regulation of ryanodine-sensitive calcium-release channel activity, peptidyl-proline modification, positive regulation of I-kappaB kinase/NF-kappaB cascade, positive regulation of protein binding, positive regulation of protein ubiquitination, protein folding, protein maturation by protein folding, protein peptidyl-prolyl isomerization, protein refolding, regulation of activin receptor signaling pathway, regulation of immune response, regulation of ryanodine-sensitive calcium-release channel activity, transforming growth factor beta receptor signaling pathway, ventricular cardiac muscle tissue morphogenesis axon, cytoplasm, cytosol, membrane, sarcoplasmic reticulum membrane, terminal cisterna FK506 binding, SMAD binding, activin binding, calcium channel inhibitor activity, macrolide binding, peptidyl-prolyl cis-trans isomerase activity, protein binding, ryanodine-sensitive calcium-release channel activity, signal transducer activity, transforming growth factor beta receptor binding, transforming growth factor beta-activated receptor activity, type I transforming growth factor beta receptor binding Human UniProtKB-KW:KW-0697 FKBP1B GOC UniProtKB {GO:0000413=PMID:7592869, GO:0005515=PMID:7592869, GO:0042542=GO_REF:0000019, GO:0019227=GO_REF:0000019, GO:0022417=PMID:11322937, GO:0005829=PMID:7592869, GO:0006939=GO_REF:0000019, GO:0042026=PMID:11322937, GO:0005737=PMID:12443530, GO:0030551=GO_REF:0000019, GO:0006936=GO_REF:0000029, GO:0006458=PMID:11322937, GO:0042098=GO_REF:0000019, GO:0006457=GO_REF:0000038, GO:0060314=PMID:7592869, GO:0033197=GO_REF:0000019, GO:0051280=PMID:12443530, GO:0010459=GO_REF:0000024, GO:0003755=PMID:7592869, GO:0005102=PMID:10830164, GO:0033017=GO_REF:0000033, GO:0010881=GO_REF:0000024, GO:0005528=PMID:7592869, GO:0014808=GO_REF:0000019, GO:1901385=PMID:17921453, GO:0034704=PMID:10830164, GO:0009749=GO_REF:0000019, GO:0044325=GO_REF:0000019, GO:0016020=PMID:12443530, GO:0018208=GO_REF:0000033, GO:0032513=PMID:7592869, GO:0051775=PMID:19226252, GO:0030073=GO_REF:0000019, GO:0061179=GO_REF:0000019, GO:0005219=PMID:11322937} P68106 Peptidyl-prolyl cis-trans isomerase FKBP1B protein 20130413 {GO:0000413=IDA, GO:0005515=IPI, GO:0042542=IEA, GO:0019227=IEA, GO:0022417=TAS, GO:0005829=IC, GO:0006939=IEA, GO:0042026=TAS, GO:0005737=IDA, GO:0030551=IEA, GO:0006936=NAS, GO:0006458=TAS, GO:0042098=IEA, GO:0006457=IEA, GO:0060314=IMP, GO:0033197=IEA, GO:0051280=IDA, GO:0010459=ISS, GO:0003755=IDA, GO:0005102=IPI, GO:0033017=IBA, GO:0010881=ISS, GO:0005528=IDA, GO:0014808=IEA, GO:1901385=IDA, GO:0034704=IDA, GO:0009749=IEA, GO:0044325=IEA, GO:0016020=IDA, GO:0018208=IBA, GO:0032513=IDA, GO:0051775=IDA, GO:0030073=IEA, GO:0061179=IEA, GO:0005219=TAS} 'de novo' protein folding, T cell proliferation, insulin secretion, muscle contraction, negative regulation of heart rate, negative regulation of insulin secretion involved in cellular response to glucose stimulus, negative regulation of protein phosphatase type 2B activity, negative regulation of release of sequestered calcium ion into cytosol, neuronal action potential propagation, peptidyl-proline modification, protein folding, protein maturation by protein folding, protein peptidyl-prolyl isomerization, protein refolding, regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion, regulation of ryanodine-sensitive calcium-release channel activity, regulation of voltage-gated calcium channel activity, release of sequestered calcium ion into cytosol by sarcoplasmic reticulum, response to glucose stimulus, response to hydrogen peroxide, response to redox state, response to vitamin E, smooth muscle contraction calcium channel complex, cytoplasm, cytosol, membrane, sarcoplasmic reticulum membrane FK506 binding, cyclic nucleotide binding, ion channel binding, peptidyl-prolyl cis-trans isomerase activity, protein binding, receptor binding, ryanodine-sensitive calcium-release channel activity Human FKBP2 GOC UniProtKB {GO:0000413=GO_REF:0000033, GO:0005515=PMID:16713569, GO:0016020=GO_REF:0000033, GO:0005783=PMID:1713687, GO:0006457=GO_REF:0000037, GO:0018208=GO_REF:0000033, GO:0005789=GO_REF:0000039, GO:0003755=GO_REF:0000033, GO:0005528=GO_REF:0000033} P26885 Peptidyl-prolyl cis-trans isomerase FKBP2 protein 20130413 {GO:0000413=IBA, GO:0005515=IPI, GO:0016020=IBA, GO:0005783=TAS, GO:0006457=IEA, GO:0018208=IBA, GO:0005789=IEA, GO:0003755=IBA, GO:0005528=IBA} peptidyl-proline modification, protein folding, protein peptidyl-prolyl isomerization endoplasmic reticulum, endoplasmic reticulum membrane, membrane FK506 binding, peptidyl-prolyl cis-trans isomerase activity, protein binding Human PANTHER:PTN000054102 FKBP3 GOC UniProtKB {GO:0000413=GO_REF:0000033, GO:0016020=GO_REF:0000033, GO:0006457=GO_REF:0000037, GO:0018208=GO_REF:0000033, GO:0003755=GO_REF:0000033, GO:0005528=GO_REF:0000033, GO:0004872=PMID:1374240, GO:0005634=GO_REF:0000033} Q00688 Peptidyl-prolyl cis-trans isomerase FKBP3 protein 20130413 {GO:0000413=IBA, GO:0016020=IBA, GO:0006457=IEA, GO:0018208=IBA, GO:0003755=IBA, GO:0005528=IBA, GO:0004872=TAS, GO:0005634=IBA} peptidyl-proline modification, protein folding, protein peptidyl-prolyl isomerization membrane, nucleus FK506 binding, peptidyl-prolyl cis-trans isomerase activity, receptor activity Human PANTHER:PTN000054102 FKBP4 GOC UniProtKB {GO:0000413=PMID:11350175, GO:0005515=PMID:12604780, GO:0051219=GO_REF:0000019, GO:0048471=GO_REF:0000019, GO:0046661=GO_REF:0000019, GO:0031503=GO_REF:0000019, GO:0005634=GO_REF:0000052, GO:0035259=GO_REF:0000019, GO:0005829=GO_REF:0000024, GO:0005622=GO_REF:0000029, GO:0005739=GO_REF:0000039, GO:0005737=GO_REF:0000052, GO:0006457=PMID:1279700, GO:0031072=PMID:9660753, GO:0043025=GO_REF:0000019, GO:0030850=GO_REF:0000019, GO:0030674=PMID:2378870, GO:0031115=GO_REF:0000019, GO:0032767=GO_REF:0000019, GO:0031111=GO_REF:0000024, GO:0007566=GO_REF:0000019, GO:0005874=GO_REF:0000037, GO:0005730=GO_REF:0000052, GO:0003755=PMID:11350175, GO:0048156=GO_REF:0000019, GO:0005528=PMID:1376003, GO:0005525=GO_REF:0000019, GO:0044295=GO_REF:0000024, GO:0005524=GO_REF:0000019, GO:0043234=GO_REF:0000019, GO:0061077=PMID:11350175, GO:0016020=GO_REF:0000033, GO:0018208=GO_REF:0000033, GO:0010977=GO_REF:0000024, GO:0006463=GO_REF:0000019, GO:0030521=GO_REF:0000019, GO:0006825=GO_REF:0000019} Q02790 Peptidyl-prolyl cis-trans isomerase FKBP4 protein 20130413 {GO:0000413=IDA, GO:0005515=IPI, GO:0051219=IEA, GO:0048471=IEA, GO:0046661=IEA, GO:0031503=IEA, GO:0005634=IDA, GO:0035259=IEA, GO:0005829=ISS, GO:0005622=NAS, GO:0005739=IEA, GO:0005737=IDA, GO:0006457=TAS, GO:0031072=IPI, GO:0043025=IEA, GO:0030850=IEA, GO:0030674=TAS, GO:0031115=IEA, GO:0032767=IEA, GO:0031111=ISS, GO:0007566=IEA, GO:0005874=IEA, GO:0005730=IDA, GO:0003755=IDA, GO:0048156=IEA, GO:0005528=TAS, GO:0005525=IEA, GO:0044295=ISS, GO:0005524=IEA, GO:0043234=IEA, GO:0061077=IDA, GO:0016020=IBA, GO:0018208=IBA, GO:0010977=ISS, GO:0006463=IEA, GO:0030521=IEA, GO:0006825=IEA} androgen receptor signaling pathway, chaperone-mediated protein folding, copper ion transport, embryo implantation, male sex differentiation, negative regulation of microtubule polymerization, negative regulation of microtubule polymerization or depolymerization, negative regulation of neuron projection development, peptidyl-proline modification, prostate gland development, protein complex localization, protein folding, protein peptidyl-prolyl isomerization, steroid hormone receptor complex assembly axonal growth cone, cytoplasm, cytosol, intracellular, membrane, microtubule, mitochondrion, neuronal cell body, nucleolus, nucleus, perinuclear region of cytoplasm, protein complex ATP binding, FK506 binding, GTP binding, copper-dependent protein binding, glucocorticoid receptor binding, heat shock protein binding, peptidyl-prolyl cis-trans isomerase activity, phosphoprotein binding, protein binding, protein binding, bridging, tau protein binding Human FKBP5 GOC UniProtKB {GO:0000413=PMID:11350175, GO:0005737=GO_REF:0000039, GO:0061077=PMID:11350175, GO:0016020=GO_REF:0000033, GO:0006457=PMID:9001212, GO:0031072=PMID:9660753, GO:0018208=GO_REF:0000033, GO:0005730=GO_REF:0000052, GO:0003755=PMID:11350175, GO:0005528=GO_REF:0000033, GO:0005634=GO_REF:0000052} Q13451 Peptidyl-prolyl cis-trans isomerase FKBP5 protein 20130413 {GO:0000413=IDA, GO:0005737=IEA, GO:0061077=IDA, GO:0016020=IBA, GO:0006457=TAS, GO:0031072=IPI, GO:0018208=IBA, GO:0005730=IDA, GO:0003755=IDA, GO:0005528=IBA, GO:0005634=IDA} chaperone-mediated protein folding, peptidyl-proline modification, protein folding, protein peptidyl-prolyl isomerization cytoplasm, membrane, nucleolus, nucleus FK506 binding, heat shock protein binding, peptidyl-prolyl cis-trans isomerase activity Human FKBP6 RefGenome UniProtKB {GO:0016020=GO_REF:0000033, GO:0000239=GO_REF:0000019, GO:0006457=GO_REF:0000037, GO:0018208=GO_REF:0000033, GO:0003755=GO_REF:0000033, GO:0005528=GO_REF:0000033, GO:0007283=GO_REF:0000019} O75344 Peptidyl-prolyl cis-trans isomerase FKBP6 protein 20110126 {GO:0016020=IBA, GO:0000239=IEA, GO:0006457=IEA, GO:0018208=IBA, GO:0003755=IBA, GO:0005528=IBA, GO:0007283=IEA} pachytene, peptidyl-proline modification, protein folding, spermatogenesis membrane FK506 binding, peptidyl-prolyl cis-trans isomerase activity Human PANTHER:PTN000054102 FKBP7 HPA UniProtKB {GO:0000413=GO_REF:0000033, GO:0016020=GO_REF:0000033, GO:0005783=GO_REF:0000052, GO:0006457=GO_REF:0000037, GO:0018208=GO_REF:0000033, GO:0005509=GO_REF:0000019, GO:0003755=GO_REF:0000033, GO:0005528=GO_REF:0000033, GO:0005788=GO_REF:0000039} Q9Y680 Peptidyl-prolyl cis-trans isomerase FKBP7 protein 20081203 {GO:0000413=IBA, GO:0016020=IBA, GO:0005783=IDA, GO:0006457=IEA, GO:0018208=IBA, GO:0005509=IEA, GO:0003755=IBA, GO:0005528=IBA, GO:0005788=IEA} peptidyl-proline modification, protein folding, protein peptidyl-prolyl isomerization endoplasmic reticulum, endoplasmic reticulum lumen, membrane FK506 binding, calcium ion binding, peptidyl-prolyl cis-trans isomerase activity Human FKBP8 GOC UniProtKB {GO:0000413=GO_REF:0000033, GO:0005515=PMID:20029029, GO:0035556=PMID:10197430, GO:0031966=GO_REF:0000039, GO:0006457=GO_REF:0000037, GO:0019048=GO_REF:0000037, GO:0018208=GO_REF:0000033, GO:0003755=GO_REF:0000033, GO:0005528=GO_REF:0000033, GO:0006915=GO_REF:0000037, GO:0030176=GO_REF:0000033, GO:0005740=GO_REF:0000033} Q14318 Peptidyl-prolyl cis-trans isomerase FKBP8 protein 20130413 {GO:0000413=IBA, GO:0005515=IPI, GO:0035556=TAS, GO:0031966=IEA, GO:0006457=IEA, GO:0019048=IEA, GO:0018208=IBA, GO:0003755=IBA, GO:0005528=IBA, GO:0006915=IEA, GO:0030176=IBA, GO:0005740=IBA} apoptotic process, intracellular signal transduction, peptidyl-proline modification, protein folding, protein peptidyl-prolyl isomerization, virus-host interaction integral to endoplasmic reticulum membrane, mitochondrial envelope, mitochondrial membrane FK506 binding, peptidyl-prolyl cis-trans isomerase activity, protein binding Human PANTHER:PTN000054102 FKBP9 GOC UniProtKB {GO:0000413=GO_REF:0000033, GO:0016020=GO_REF:0000033, GO:0005783=GO_REF:0000033, GO:0006457=GO_REF:0000024, GO:0018208=GO_REF:0000033, GO:0005509=GO_REF:0000024, GO:0003755=GO_REF:0000033, GO:0005528=GO_REF:0000033} O95302 Peptidyl-prolyl cis-trans isomerase FKBP9 protein 20130413 {GO:0000413=IBA, GO:0016020=IBA, GO:0005783=IBA, GO:0006457=ISS, GO:0018208=IBA, GO:0005509=ISS, GO:0003755=IBA, GO:0005528=IBA} peptidyl-proline modification, protein folding, protein peptidyl-prolyl isomerization endoplasmic reticulum, membrane FK506 binding, calcium ion binding, peptidyl-prolyl cis-trans isomerase activity Human PANTHER:PTN000054102 FKBP9L InterPro UniProtKB {GO:0006457=GO_REF:0000002, GO:0005509=GO_REF:0000002} Q75LS8 Putative FK506-binding protein 9-like protein protein 20130413 {GO:0006457=IEA, GO:0005509=IEA} protein folding calcium ion binding Human InterPro:IPR001179 FKBPL GOC UniProtKB {GO:0000413=GO_REF:0000033, GO:0009314=PMID:10521921, GO:0016020=GO_REF:0000033, GO:0018208=GO_REF:0000033, GO:0003755=GO_REF:0000033, GO:0005528=GO_REF:0000033, GO:0005634=GO_REF:0000033} Q9UIM3 FK506-binding protein-like protein 20130413 {GO:0000413=IBA, GO:0009314=NAS, GO:0016020=IBA, GO:0018208=IBA, GO:0003755=IBA, GO:0005528=IBA, GO:0005634=IBA} peptidyl-proline modification, protein peptidyl-prolyl isomerization, response to radiation membrane, nucleus FK506 binding, peptidyl-prolyl cis-trans isomerase activity Human PANTHER:PTN000054102 FKTN BHF-UCL UniProtKB {GO:0005801=PMID:15213246, GO:0005794=PMID:18808525, GO:0008285=PMID:18808525, GO:0005783=PMID:18808525, GO:0005634=PMID:18808525, GO:0060049=PMID:18808525, GO:0005615=PMID:9690476, GO:0007399=PMID:9690476, GO:0007517=PMID:9690476, GO:0046329=PMID:18808525, GO:0000139=GO_REF:0000039, GO:0016021=GO_REF:0000037, GO:0016740=GO_REF:0000037} O75072 Fukutin protein 20110404 {GO:0005801=IDA, GO:0005794=IDA, GO:0008285=IMP, GO:0005783=IDA, GO:0005634=IDA, GO:0060049=NAS, GO:0005615=TAS, GO:0007399=TAS, GO:0007517=TAS, GO:0046329=IMP, GO:0000139=IEA, GO:0016021=IEA, GO:0016740=IEA} muscle organ development, negative regulation of JNK cascade, negative regulation of cell proliferation, nervous system development, regulation of protein glycosylation Golgi apparatus, Golgi membrane, cis-Golgi network, endoplasmic reticulum, extracellular space, integral to membrane, nucleus transferase activity Human FLAD1 Reactome UniProtKB {GO:0006771=Reactome:REACT_11070, GO:0003919=GO_REF:0000003, GO:0006766=Reactome:REACT_11193, GO:0006777=GO_REF:0000002, GO:0006767=Reactome:REACT_11238, GO:0044281=Reactome:REACT_111217, GO:0003824=GO_REF:0000002, GO:0005524=GO_REF:0000037, GO:0005829=Reactome:REACT_11128, GO:0006747=GO_REF:0000041} Q8NFF5 FAD synthase protein 20130301 {GO:0006771=TAS, GO:0003919=IEA, GO:0006766=TAS, GO:0006777=IEA, GO:0006767=TAS, GO:0044281=TAS, GO:0003824=IEA, GO:0005524=IEA, GO:0005829=TAS, GO:0006747=IEA} FAD biosynthetic process, Mo-molybdopterin cofactor biosynthetic process, riboflavin metabolic process, small molecule metabolic process, vitamin metabolic process, water-soluble vitamin metabolic process cytosol ATP binding, FMN adenylyltransferase activity, catalytic activity Human FLCN HPA UniProtKB {GO:0005515=PMID:17028174, GO:0051898=GO_REF:0000024, GO:0032006=GO_REF:0000024, GO:0032007=GO_REF:0000024, GO:0030308=PMID:20573232, GO:0032008=GO_REF:0000024, GO:0005886=GO_REF:0000052, GO:0035065=GO_REF:0000024, GO:0005634=PMID:17028174, GO:0032403=PMID:17028174, GO:0005737=GO_REF:0000052, GO:0070373=GO_REF:0000024, GO:0030511=GO_REF:0000024, GO:2001170=GO_REF:0000024, GO:0030097=GO_REF:0000024, GO:0031929=PMID:17028174, GO:1901723=GO_REF:0000024, GO:0030336=PMID:22965878, GO:0043065=GO_REF:0000024, GO:0006950=PMID:17028174, GO:0010823=GO_REF:0000024, GO:0001701=GO_REF:0000024, GO:0045785=PMID:21209915, GO:0010628=GO_REF:0000024, GO:2000973=GO_REF:0000024, GO:0010629=GO_REF:0000024, GO:0001934=GO_REF:0000024, GO:0007043=GO_REF:0000024, GO:0001932=PMID:18663353, GO:2000506=GO_REF:0000024} Q8NFG4 Folliculin protein 20101115 {GO:0005515=IPI, GO:0051898=ISS, GO:0032006=ISS, GO:0032007=ISS, GO:0030308=IDA, GO:0032008=ISS, GO:0005886=IDA, GO:0035065=ISS, GO:0005634=IDA, GO:0032403=IDA, GO:0005737=IDA, GO:0070373=ISS, GO:0030511=ISS, GO:2001170=ISS, GO:0030097=ISS, GO:0031929=IMP, GO:1901723=ISS, GO:0030336=IMP, GO:0043065=ISS, GO:0006950=IMP, GO:0010823=ISS, GO:0001701=ISS, GO:0045785=IMP, GO:0010628=ISS, GO:2000973=ISS, GO:0010629=ISS, GO:0001934=ISS, GO:0007043=ISS, GO:0001932=IDA, GO:2000506=ISS} TOR signaling cascade, cell-cell junction assembly, hemopoiesis, in utero embryonic development, negative regulation of ATP biosynthetic process, negative regulation of ERK1 and ERK2 cascade, negative regulation of TOR signaling cascade, negative regulation of cell growth, negative regulation of cell migration, negative regulation of cell proliferation involved in kidney development, negative regulation of energy homeostasis, negative regulation of gene expression, negative regulation of mitochondrion organization, negative regulation of protein kinase B signaling cascade, positive regulation of TOR signaling cascade, positive regulation of apoptotic process, positive regulation of cell adhesion, positive regulation of gene expression, positive regulation of protein phosphorylation, positive regulation of transforming growth factor beta receptor signaling pathway, regulation of TOR signaling cascade, regulation of histone acetylation, regulation of pro-B cell differentiation, regulation of protein phosphorylation, response to stress cytoplasm, nucleus, plasma membrane protein binding, protein complex binding Human FLG BHF-UCL UniProtKB {GO:0005882=PMID:2740331, GO:0030216=PMID:17704059, GO:0005198=PMID:2740331, GO:0005509=GO_REF:0000002, GO:0016023=PMID:12850301, GO:0007275=PMID:2740331, GO:0001533=GO_REF:0000019} P20930 Filaggrin protein 20081118 {GO:0005882=NAS, GO:0030216=TAS, GO:0005198=NAS, GO:0005509=IEA, GO:0016023=IDA, GO:0007275=NAS, GO:0001533=IEA} keratinocyte differentiation, multicellular organismal development cornified envelope, cytoplasmic membrane-bounded vesicle, intermediate filament calcium ion binding, structural molecule activity Human FLG2 InterPro UniProtKB {GO:0005198=GO_REF:0000002, GO:0005509=GO_REF:0000002} Q5D862 Filaggrin-2 protein 20130413 {GO:0005198=IEA, GO:0005509=IEA} calcium ion binding, structural molecule activity Human InterPro:IPR001751|InterPro:IPR002048|InterPro:IPR011992 FLI1 PINC UniProtKB {GO:0007599=PMID:10891501, GO:0043565=GO_REF:0000002, GO:0003700=GO_REF:0000002, GO:0008015=GO_REF:0000019, GO:0009887=GO_REF:0000019, GO:0000980=GO_REF:0000019, GO:0005634=GO_REF:0000039, GO:0003677=PMID:1522903, GO:0006351=GO_REF:0000037} Q01543 Friend leukemia integration 1 transcription factor protein 20030904 {GO:0007599=TAS, GO:0043565=IEA, GO:0003700=IEA, GO:0008015=IEA, GO:0009887=IEA, GO:0000980=IEA, GO:0005634=IEA, GO:0003677=TAS, GO:0006351=IEA} blood circulation, hemostasis, organ morphogenesis, transcription, DNA-dependent nucleus DNA binding, RNA polymerase II distal enhancer sequence-specific DNA binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity Human FLII HPA UniProtKB {GO:0005515=PMID:10366446, GO:0005813=GO_REF:0000052, GO:0005737=GO_REF:0000052, GO:0006355=GO_REF:0000037, GO:0006936=PMID:9177775, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0007275=GO_REF:0000019, GO:0003779=GO_REF:0000037, GO:0005925=GO_REF:0000039, GO:0006351=GO_REF:0000037} Q13045 Protein flightless-1 homolog protein 20080818 {GO:0005515=IPI, GO:0005813=IDA, GO:0005737=IDA, GO:0006355=IEA, GO:0006936=TAS, GO:0005730=IDA, GO:0005634=IDA, GO:0007275=IEA, GO:0003779=IEA, GO:0005925=IEA, GO:0006351=IEA} multicellular organismal development, muscle contraction, regulation of transcription, DNA-dependent, transcription, DNA-dependent centrosome, cytoplasm, focal adhesion, nucleolus, nucleus actin binding, protein binding Human FLNA UniProtKB UniProtKB {GO:0005802=GO_REF:0000019, GO:0005515=PMID:10692483, GO:0031267=PMID:10051605, GO:0005886=GO_REF:0000052, GO:0031523=PMID:18548008, GO:0005634=PMID:15684392, GO:0007195=PMID:10692483, GO:0001837=GO_REF:0000019, GO:0045022=GO_REF:0000019, GO:0015629=GO_REF:0000052, GO:0042993=PMID:15684392, GO:0042803=PMID:2391361, GO:0043433=PMID:15684392, GO:0045184=PMID:18322202, GO:0005829=Reactome:REACT_23834, GO:0005737=GO_REF:0000052, GO:0001948=PMID:3138234, GO:0051015=PMID:4044584, GO:0005080=GO_REF:0000019, GO:0051764=PMID:10051605, GO:0004871=PMID:12761501, GO:0090307=PMID:18548008, GO:0043123=PMID:12761501, GO:0005938=GO_REF:0000039, GO:0034988=PMID:1833070, GO:0031532=PMID:10051605, GO:0042177=PMID:18322202, GO:0034329=Reactome:REACT_20676, GO:0051220=PMID:17536008, GO:0050821=PMID:18322202, GO:0030168=Reactome:REACT_798, GO:0003779=GO_REF:0000038, GO:0005576=Reactome:REACT_21347, GO:0048365=PMID:10051605, GO:0042384=PMID:22121117, GO:0007596=Reactome:REACT_604, GO:0034394=PMID:18322202, GO:0002576=Reactome:REACT_318, GO:0043113=PMID:10692483, GO:0017048=PMID:10051605, GO:0017160=PMID:10051605, GO:0008134=PMID:15684392} Q5HY54 Filamin-A protein 20130413 {GO:0005802=IEA, GO:0005515=IPI, GO:0031267=IDA, GO:0005886=IDA, GO:0031523=IDA, GO:0005634=IDA, GO:0007195=IMP, GO:0001837=IEA, GO:0045022=IEA, GO:0015629=IDA, GO:0042993=IMP, GO:0042803=IDA, GO:0043433=IDA, GO:0045184=IDA, GO:0005829=TAS, GO:0005737=IDA, GO:0001948=IDA, GO:0051015=IDA, GO:0005080=IEA, GO:0051764=IDA, GO:0004871=IMP, GO:0090307=IDA, GO:0043123=IMP, GO:0005938=IEA, GO:0034988=IDA, GO:0031532=IDA, GO:0042177=IMP, GO:0034329=TAS, GO:0051220=IMP, GO:0050821=IMP, GO:0030168=TAS, GO:0003779=IEA, GO:0005576=TAS, GO:0048365=IDA, GO:0042384=IMP, GO:0007596=TAS, GO:0034394=IDA, GO:0002576=TAS, GO:0043113=IDA, GO:0017048=IDA, GO:0017160=IDA, GO:0008134=IPI} actin crosslink formation, actin cytoskeleton reorganization, adenylate cyclase-inhibiting dopamine receptor signaling pathway, blood coagulation, cell junction assembly, cilium assembly, cytoplasmic sequestering of protein, early endosome to late endosome transport, epithelial to mesenchymal transition, establishment of protein localization, negative regulation of protein catabolic process, negative regulation of sequence-specific DNA binding transcription factor activity, platelet activation, platelet degranulation, positive regulation of I-kappaB kinase/NF-kappaB cascade, positive regulation of transcription factor import into nucleus, protein localization to cell surface, protein stabilization, receptor clustering, spindle assembly involved in mitosis Myb complex, actin cytoskeleton, cell cortex, cytoplasm, cytosol, extracellular region, nucleus, plasma membrane, trans-Golgi network Fc-gamma receptor I complex binding, Rac GTPase binding, Ral GTPase binding, Rho GTPase binding, actin binding, actin filament binding, glycoprotein binding, protein binding, protein homodimerization activity, protein kinase C binding, signal transducer activity, small GTPase binding, transcription factor binding Human UniProtKB-KW:KW-0009 FLNB HPA UniProtKB {GO:0005515=PMID:10644691, GO:0001725=GO_REF:0000019, GO:0030018=GO_REF:0000039, GO:0030036=PMID:8327473, GO:0005886=GO_REF:0000052, GO:0019221=Reactome:REACT_25229, GO:0003779=PMID:8327473, GO:0015629=PMID:9651345, GO:0030154=GO_REF:0000037, GO:0042802=PMID:12393796, GO:0005829=Reactome:REACT_115658, GO:0007165=PMID:8327473, GO:0005737=GO_REF:0000052, GO:0007519=GO_REF:0000019, GO:0016021=PMID:8327473, GO:0005938=GO_REF:0000039, GO:0007016=PMID:9694715, GO:0005925=GO_REF:0000019} O75369 Filamin-B protein 20101115 {GO:0005515=IPI, GO:0001725=IEA, GO:0030018=IEA, GO:0030036=TAS, GO:0005886=IDA, GO:0019221=TAS, GO:0003779=NAS, GO:0015629=TAS, GO:0030154=IEA, GO:0042802=IPI, GO:0005829=TAS, GO:0007165=TAS, GO:0005737=IDA, GO:0007519=IEA, GO:0016021=NAS, GO:0005938=IEA, GO:0007016=TAS, GO:0005925=IEA} actin cytoskeleton organization, cell differentiation, cytokine-mediated signaling pathway, cytoskeletal anchoring at plasma membrane, signal transduction, skeletal muscle tissue development Z disc, actin cytoskeleton, cell cortex, cytoplasm, cytosol, focal adhesion, integral to membrane, plasma membrane, stress fiber actin binding, identical protein binding, protein binding Human FLNC BHF-UCL UniProtKB {GO:0005515=PMID:17474147, GO:0008092=PMID:17987659, GO:0030018=GO_REF:0000039, GO:0005886=GO_REF:0000052, GO:0034329=Reactome:REACT_20676, GO:0030506=PMID:21223964, GO:0003779=GO_REF:0000037, GO:0005829=Reactome:REACT_20513, GO:0048747=GO_REF:0000019, GO:0042383=PMID:21223964, GO:0016528=GO_REF:0000019, GO:0005737=GO_REF:0000052, GO:0043034=PMID:21223964, GO:0005856=GO_REF:0000039} Q14315 Filamin-C protein 20120606 {GO:0005515=IPI, GO:0008092=IPI, GO:0030018=IEA, GO:0005886=IDA, GO:0034329=TAS, GO:0030506=IPI, GO:0003779=IEA, GO:0005829=TAS, GO:0048747=IEA, GO:0042383=IDA, GO:0016528=IEA, GO:0005737=IDA, GO:0043034=TAS, GO:0005856=IEA} cell junction assembly, muscle fiber development Z disc, costamere, cytoplasm, cytoskeleton, cytosol, plasma membrane, sarcolemma, sarcoplasm actin binding, ankyrin binding, cytoskeletal protein binding, protein binding Human FLOT1 BHF-UCL UniProtKB {GO:0005515=PMID:15469992, GO:0042470=GO_REF:0000039, GO:0005815=PMID:18000879, GO:0035023=GO_REF:0000019, GO:0034451=PMID:18000879, GO:0007409=GO_REF:0000019, GO:0072659=GO_REF:0000019, GO:0016600=GO_REF:0000019, GO:0042383=GO_REF:0000019, GO:0035255=GO_REF:0000019, GO:0008180=PMID:18850735, GO:0005901=PMID:9153235, GO:0045121=PMID:15469992, GO:0016021=PMID:9153235, GO:0005768=PMID:20682791} O75955 Flotillin-1 protein 20080604 {GO:0005515=IPI, GO:0042470=IEA, GO:0005815=IDA, GO:0035023=IEA, GO:0034451=IDA, GO:0007409=IEA, GO:0072659=IEA, GO:0016600=IEA, GO:0042383=IEA, GO:0035255=IEA, GO:0008180=IDA, GO:0005901=TAS, GO:0045121=IDA, GO:0016021=TAS, GO:0005768=IDA} axonogenesis, protein localization to plasma membrane, regulation of Rho protein signal transduction caveola, centriolar satellite, endosome, flotillin complex, integral to membrane, melanosome, membrane raft, microtubule organizing center, sarcolemma, signalosome ionotropic glutamate receptor binding, protein binding Human FLOT2 PINC UniProtKB {GO:0008544=PMID:8051082, GO:0005886=PMID:1769667, GO:0009986=PMID:12493773, GO:0035255=GO_REF:0000019, GO:0030139=PMID:20682791, GO:0007155=GO_REF:0000037, GO:0002080=GO_REF:0000019, GO:0016600=GO_REF:0000019, GO:0005768=PMID:20682791} Q14254 Flotillin-2 protein 20030904 {GO:0008544=TAS, GO:0005886=NAS, GO:0009986=IDA, GO:0035255=IEA, GO:0030139=IDA, GO:0007155=IEA, GO:0002080=IEA, GO:0016600=IEA, GO:0005768=IDA} cell adhesion, epidermis development acrosomal membrane, cell surface, endocytic vesicle, endosome, flotillin complex, plasma membrane ionotropic glutamate receptor binding Human FLRT1 UniProtKB UniProtKB {GO:0008150=GO_REF:0000015, GO:0005887=PMID:10644439, GO:0005578=PMID:10644439, GO:0005057=PMID:10644439, GO:0030674=PMID:10644439, GO:0007155=GO_REF:0000037} Q9NZU1 Leucine-rich repeat transmembrane protein FLRT1 protein 20061026 {GO:0008150=ND, GO:0005887=NAS, GO:0005578=NAS, GO:0005057=NAS, GO:0030674=NAS, GO:0007155=IEA} biological_process, cell adhesion integral to plasma membrane, proteinaceous extracellular matrix protein binding, bridging, receptor signaling protein activity Human FLRT2 UniProtKB UniProtKB {GO:0008150=GO_REF:0000015, GO:0005887=PMID:10644439, GO:0005578=PMID:10644439, GO:0005057=PMID:10644439, GO:0030674=PMID:10644439, GO:0007155=GO_REF:0000037} O43155 Leucine-rich repeat transmembrane protein FLRT2 protein 20010822 {GO:0008150=ND, GO:0005887=NAS, GO:0005578=NAS, GO:0005057=NAS, GO:0030674=NAS, GO:0007155=IEA} biological_process, cell adhesion integral to plasma membrane, proteinaceous extracellular matrix protein binding, bridging, receptor signaling protein activity Human FLRT3 UniProtKB UniProtKB {GO:0008150=GO_REF:0000015, GO:0005887=PMID:10644439, GO:0005578=PMID:10644439, GO:0005057=PMID:10644439, GO:0030674=PMID:10644439, GO:0007155=GO_REF:0000037} Q9NZU0 Leucine-rich repeat transmembrane protein FLRT3 protein 20010822 {GO:0008150=ND, GO:0005887=NAS, GO:0005578=NAS, GO:0005057=NAS, GO:0030674=NAS, GO:0007155=IEA} biological_process, cell adhesion integral to plasma membrane, proteinaceous extracellular matrix protein binding, bridging, receptor signaling protein activity Human FLT1 HPA UniProtKB {GO:0005515=PMID:10543948, GO:0030949=PMID:1312256, GO:0008284=PMID:10748050, GO:0035924=PMID:8605350, GO:0005886=GO_REF:0000052, GO:0048514=GO_REF:0000024, GO:0005634=GO_REF:0000052, GO:0002040=GO_REF:0000019, GO:0048598=GO_REF:0000024, GO:0005615=PMID:8248162, GO:0030154=GO_REF:0000037, GO:0042802=GO_REF:0000019, GO:0005737=GO_REF:0000052, GO:0046777=PMID:9299537, GO:0043552=PMID:11312102, GO:0019838=PMID:1312256, GO:0043406=PMID:9299537, GO:0036323=PMID:15952180, GO:0005021=PMID:1312256, GO:0048010=Reactome:REACT_12529, GO:0001569=GO_REF:0000019, GO:0005794=GO_REF:0000052, GO:0030335=PMID:8605350, GO:0005730=GO_REF:0000052, GO:0036326=PMID:8605350, GO:0036327=PMID:15952180, GO:0018108=PMID:9299537, GO:0014068=PMID:14633857, GO:0005524=GO_REF:0000037, GO:0045766=PMID:14633857, GO:0010863=PMID:11312102, GO:0002548=PMID:8605350, GO:0016477=PMID:8605350, GO:0005887=PMID:11513746, GO:0036332=PMID:12796773, GO:0004713=GO_REF:0000002, GO:0004714=PMID:8248162, GO:0043410=PMID:9299537, GO:0007169=PMID:2158038, GO:0005768=GO_REF:0000039} P17948 Vascular endothelial growth factor receptor 1 protein 20101115 {GO:0005515=IPI, GO:0030949=IDA, GO:0008284=TAS, GO:0035924=IDA, GO:0005886=IDA, GO:0048514=ISS, GO:0005634=IDA, GO:0002040=IEA, GO:0048598=ISS, GO:0005615=TAS, GO:0030154=IEA, GO:0042802=IEA, GO:0005737=IDA, GO:0046777=IDA, GO:0043552=IMP, GO:0019838=IPI, GO:0043406=IDA, GO:0036323=IDA, GO:0005021=IDA, GO:0048010=TAS, GO:0001569=IEA, GO:0005794=IDA, GO:0030335=IDA, GO:0005730=IDA, GO:0036326=IDA, GO:0036327=IDA, GO:0018108=IDA, GO:0014068=IMP, GO:0005524=IEA, GO:0045766=IMP, GO:0010863=IMP, GO:0002548=IDA, GO:0016477=IMP, GO:0005887=IDA, GO:0036332=IDA, GO:0004713=IEA, GO:0004714=TAS, GO:0043410=IDA, GO:0007169=TAS, GO:0005768=IEA} blood vessel morphogenesis, cell differentiation, cell migration, cellular response to vascular endothelial growth factor stimulus, embryonic morphogenesis, monocyte chemotaxis, patterning of blood vessels, peptidyl-tyrosine phosphorylation, positive regulation of MAP kinase activity, positive regulation of MAPK cascade, positive regulation of angiogenesis, positive regulation of cell migration, positive regulation of cell proliferation, positive regulation of phosphatidylinositol 3-kinase activity, positive regulation of phosphatidylinositol 3-kinase cascade, positive regulation of phospholipase C activity, positive regulation of vascular endothelial growth factor receptor signaling pathway, protein autophosphorylation, sprouting angiogenesis, transmembrane receptor protein tyrosine kinase signaling pathway, vascular endothelial growth factor receptor signaling pathway, vascular endothelial growth factor receptor-1 signaling pathway Golgi apparatus, cytoplasm, endosome, extracellular space, integral to plasma membrane, nucleolus, nucleus, plasma membrane ATP binding, VEGF-A-activated receptor activity, VEGF-B-activated receptor activity, growth factor binding, identical protein binding, placental growth factor-activated receptor activity, protein binding, protein tyrosine kinase activity, transmembrane receptor protein tyrosine kinase activity, vascular endothelial growth factor-activated receptor activity Human FLT3 UniProtKB UniProtKB {GO:0005515=PMID:20098747, GO:0045578=GO_REF:0000019, GO:0008284=PMID:19549778, GO:0008285=GO_REF:0000019, GO:0019221=GO_REF:0000024, GO:0097028=GO_REF:0000024, GO:0042803=PMID:19549778, GO:0046777=PMID:19549778, GO:0043552=PMID:12951584, GO:0043406=PMID:19549778, GO:0030183=GO_REF:0000024, GO:0005021=PMID:8394751, GO:0002328=GO_REF:0000024, GO:0035726=GO_REF:0000024, GO:0038084=PMID:8394751, GO:0001776=GO_REF:0000024, GO:0030097=PMID:7507245, GO:0004896=GO_REF:0000024, GO:0042531=PMID:19549778, GO:0009986=GO_REF:0000019, GO:0018108=PMID:19549778, GO:0014068=PMID:12951584, GO:0042981=PMID:19549778, GO:0005524=GO_REF:0000038, GO:0002572=GO_REF:0000019, GO:0016020=GO_REF:0000002, GO:0005887=PMID:8394751, GO:0071345=GO_REF:0000024, GO:0005788=GO_REF:0000039, GO:0046651=GO_REF:0000024, GO:0016021=GO_REF:0000038, GO:0002318=GO_REF:0000024, GO:0004714=GO_REF:0000002, GO:0043410=PMID:19549778, GO:0007169=GO_REF:0000002, GO:0043548=GO_REF:0000019} Q5VTU6 Receptor-type tyrosine-protein kinase FLT3 protein 20130413 {GO:0005515=IPI, GO:0045578=IEA, GO:0008284=TAS, GO:0008285=IEA, GO:0019221=ISS, GO:0097028=ISS, GO:0042803=TAS, GO:0046777=TAS, GO:0043552=TAS, GO:0043406=TAS, GO:0030183=ISS, GO:0005021=TAS, GO:0002328=ISS, GO:0035726=ISS, GO:0038084=TAS, GO:0001776=ISS, GO:0030097=IDA, GO:0004896=ISS, GO:0042531=TAS, GO:0009986=IEA, GO:0018108=TAS, GO:0014068=TAS, GO:0042981=TAS, GO:0005524=IEA, GO:0002572=IEA, GO:0016020=IEA, GO:0005887=TAS, GO:0071345=ISS, GO:0005788=IEA, GO:0046651=ISS, GO:0016021=IEA, GO:0002318=ISS, GO:0004714=IEA, GO:0043410=TAS, GO:0007169=IEA, GO:0043548=IEA} B cell differentiation, cellular response to cytokine stimulus, common myeloid progenitor cell proliferation, cytokine-mediated signaling pathway, dendritic cell differentiation, hemopoiesis, leukocyte homeostasis, lymphocyte proliferation, myeloid progenitor cell differentiation, negative regulation of B cell differentiation, negative regulation of cell proliferation, peptidyl-tyrosine phosphorylation, positive regulation of MAP kinase activity, positive regulation of MAPK cascade, positive regulation of cell proliferation, positive regulation of phosphatidylinositol 3-kinase activity, positive regulation of phosphatidylinositol 3-kinase cascade, positive regulation of tyrosine phosphorylation of STAT protein, pro-B cell differentiation, pro-T cell differentiation, protein autophosphorylation, regulation of apoptotic process, transmembrane receptor protein tyrosine kinase signaling pathway, vascular endothelial growth factor signaling pathway cell surface, endoplasmic reticulum lumen, integral to membrane, integral to plasma membrane, membrane ATP binding, cytokine receptor activity, phosphatidylinositol 3-kinase binding, protein binding, protein homodimerization activity, transmembrane receptor protein tyrosine kinase activity, vascular endothelial growth factor-activated receptor activity Human UniProtKB-KW:KW-0812 FLT3LG ENSEMBL UniProtKB {GO:0030971=GO_REF:0000019, GO:0008284=GO_REF:0000019, GO:0005886=GO_REF:0000039, GO:0005102=PMID:8180375, GO:0032825=GO_REF:0000019, GO:0005125=GO_REF:0000002, GO:0005615=GO_REF:0000037, GO:0042803=GO_REF:0000019, GO:0031233=GO_REF:0000019, GO:0007165=PMID:8180375, GO:0016020=PMID:8145851, GO:0030098=GO_REF:0000019, GO:0016021=PMID:8180375, GO:0035162=PMID:21149635} Q05C96 cDNA FLJ61175, highly similar to SL cytokine protein 20130413 {GO:0030971=IEA, GO:0008284=IEA, GO:0005886=IEA, GO:0005102=TAS, GO:0032825=IEA, GO:0005125=IEA, GO:0005615=IEA, GO:0042803=IEA, GO:0031233=IEA, GO:0007165=TAS, GO:0016020=NAS, GO:0030098=IEA, GO:0016021=NAS, GO:0035162=IDA} embryonic hemopoiesis, lymphocyte differentiation, positive regulation of cell proliferation, positive regulation of natural killer cell differentiation, signal transduction extracellular space, integral to membrane, intrinsic to external side of plasma membrane, membrane, plasma membrane cytokine activity, protein homodimerization activity, receptor binding, receptor tyrosine kinase binding Human Ensembl:ENSMUSP00000082492 FLT4 BHF-UCL UniProtKB {GO:0005515=PMID:22939624, GO:0008284=PMID:11574540, GO:0035924=PMID:19779139, GO:0005886=Reactome:REACT_12533, GO:0048514=GO_REF:0000024, GO:0046330=PMID:16076871, GO:0005634=GO_REF:0000039, GO:0002040=GO_REF:0000024, GO:0001946=PMID:19779139, GO:0005737=GO_REF:0000039, GO:0046777=PMID:7675451, GO:0090037=PMID:11532940, GO:0060312=GO_REF:0000024, GO:0019838=PMID:9435229, GO:0005021=PMID:9012504, GO:0070374=PMID:11532940, GO:0001945=GO_REF:0000024, GO:0001944=GO_REF:0000024, GO:0048010=Reactome:REACT_12529, GO:0043066=PMID:11532940, GO:0019903=PMID:20826270, GO:0018108=PMID:7898938, GO:0005576=GO_REF:0000039, GO:0005524=GO_REF:0000037, GO:0010575=PMID:19779139, GO:0010595=PMID:11532940, GO:0001938=PMID:11532940, GO:0005887=GO_REF:0000002, GO:0001934=PMID:11532940, GO:0004714=PMID:7898938, GO:0043410=PMID:19779139, GO:0007169=PMID:10835628} P35916 Vascular endothelial growth factor receptor 3 protein 20120319 {GO:0005515=IPI, GO:0008284=IGI, GO:0035924=IMP, GO:0005886=TAS, GO:0048514=ISS, GO:0046330=IMP, GO:0005634=IEA, GO:0002040=ISS, GO:0001946=IMP, GO:0005737=IEA, GO:0046777=IDA, GO:0090037=IMP, GO:0060312=ISS, GO:0019838=IPI, GO:0005021=IDA, GO:0070374=IMP, GO:0001945=ISS, GO:0001944=ISS, GO:0048010=TAS, GO:0043066=IMP, GO:0019903=IPI, GO:0018108=IDA, GO:0005576=IEA, GO:0005524=IEA, GO:0010575=IMP, GO:0010595=IMP, GO:0001938=IMP, GO:0005887=IEA, GO:0001934=IMP, GO:0004714=IMP, GO:0043410=IMP, GO:0007169=TAS} blood vessel morphogenesis, cellular response to vascular endothelial growth factor stimulus, lymph vessel development, lymphangiogenesis, negative regulation of apoptotic process, peptidyl-tyrosine phosphorylation, positive regulation of ERK1 and ERK2 cascade, positive regulation of JNK cascade, positive regulation of MAPK cascade, positive regulation of cell proliferation, positive regulation of endothelial cell migration, positive regulation of endothelial cell proliferation, positive regulation of protein kinase C signaling cascade, positive regulation of protein phosphorylation, positive regulation vascular endothelial growth factor production, protein autophosphorylation, regulation of blood vessel remodeling, sprouting angiogenesis, transmembrane receptor protein tyrosine kinase signaling pathway, vascular endothelial growth factor receptor signaling pathway, vasculature development cytoplasm, extracellular region, integral to plasma membrane, nucleus, plasma membrane ATP binding, growth factor binding, protein binding, protein phosphatase binding, transmembrane receptor protein tyrosine kinase activity, vascular endothelial growth factor-activated receptor activity Human UniProtKB:P35917 FLVCR1 Reactome UniProtKB {GO:0005515=PMID:20610401, GO:0005215=PMID:10648427, GO:0008219=GO_REF:0000037, GO:0046620=GO_REF:0000019, GO:0005886=Reactome:REACT_25203, GO:0015232=PMID:20610401, GO:0007275=PMID:10648427, GO:0048536=GO_REF:0000019, GO:0097037=PMID:15369674, GO:0055085=Reactome:REACT_15518, GO:0001701=GO_REF:0000019, GO:0006879=Reactome:REACT_25060, GO:0035264=GO_REF:0000019, GO:0005887=PMID:10648427, GO:0060323=GO_REF:0000019, GO:0030218=GO_REF:0000019, GO:0006810=PMID:10648427, GO:0016021=GO_REF:0000002, GO:0042733=GO_REF:0000019} Q9Y5Y0 Feline leukemia virus subgroup C receptor-related protein 1 protein 20130301 {GO:0005515=IPI, GO:0005215=TAS, GO:0008219=IEA, GO:0046620=IEA, GO:0005886=TAS, GO:0015232=IDA, GO:0007275=TAS, GO:0048536=IEA, GO:0097037=IMP, GO:0055085=TAS, GO:0001701=IEA, GO:0006879=TAS, GO:0035264=IEA, GO:0005887=TAS, GO:0060323=IEA, GO:0030218=IEA, GO:0006810=TAS, GO:0016021=IEA, GO:0042733=IEA} cell death, cellular iron ion homeostasis, embryonic digit morphogenesis, erythrocyte differentiation, head morphogenesis, heme export, in utero embryonic development, multicellular organism growth, multicellular organismal development, regulation of organ growth, spleen development, transmembrane transport, transport integral to membrane, integral to plasma membrane, plasma membrane heme transporter activity, protein binding, transporter activity Human FLYWCH1 HPA UniProtKB {GO:0005737=GO_REF:0000052, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0003677=GO_REF:0000037, GO:0046872=GO_REF:0000037} Q4VC44 FLYWCH-type zinc finger-containing protein 1 protein 20111111 {GO:0005737=IDA, GO:0005730=IDA, GO:0005634=IDA, GO:0003677=IEA, GO:0046872=IEA} cytoplasm, nucleolus, nucleus DNA binding, metal ion binding Human FLYWCH2 UniProtKB UniProtKB {GO:0003674=GO_REF:0000015, GO:0008150=GO_REF:0000015, GO:0005575=GO_REF:0000015} Q96CP2 FLYWCH family member 2 protein 20110303 {GO:0003674=ND, GO:0008150=ND, GO:0005575=ND} biological_process cellular_component molecular_function Human FMN1 UniProtKB UniProtKB {GO:0035137=GO_REF:0000019, GO:0010467=GO_REF:0000019, GO:0035136=GO_REF:0000019, GO:0017124=GO_REF:0000019, GO:0030036=GO_REF:0000002, GO:0005886=GO_REF:0000039, GO:0048705=GO_REF:0000019, GO:0003779=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0015629=GO_REF:0000002, GO:0003677=GO_REF:0000019, GO:0005737=GO_REF:0000039, GO:0005912=GO_REF:0000039, GO:0030838=GO_REF:0000019, GO:0051127=GO_REF:0000019} Q68DA7 Formin-1 protein 20130413 {GO:0035137=IEA, GO:0010467=IEA, GO:0035136=IEA, GO:0017124=IEA, GO:0030036=IEA, GO:0005886=IEA, GO:0048705=IEA, GO:0003779=IEA, GO:0005634=IEA, GO:0015629=IEA, GO:0003677=IEA, GO:0005737=IEA, GO:0005912=IEA, GO:0030838=IEA, GO:0051127=IEA} actin cytoskeleton organization, forelimb morphogenesis, gene expression, hindlimb morphogenesis, positive regulation of actin filament polymerization, positive regulation of actin nucleation, skeletal system morphogenesis actin cytoskeleton, adherens junction, cytoplasm, nucleus, plasma membrane DNA binding, SH3 domain binding, actin binding Human UniProtKB-SubCell:SL-0009 FMNL1 IntAct UniProtKB {GO:0005515=PMID:21148482, GO:0030036=GO_REF:0000002, GO:0005886=GO_REF:0000024, GO:0006929=GO_REF:0000019, GO:0008360=PMID:21834987, GO:0003779=GO_REF:0000002, GO:0005829=GO_REF:0000024, GO:0045335=GO_REF:0000024, GO:0032794=PMID:21148482, GO:0051014=GO_REF:0000024, GO:0003674=GO_REF:0000015, GO:0048365=GO_REF:0000024, GO:0032059=GO_REF:0000039, GO:0051015=GO_REF:0000024, GO:0030866=PMID:21834987, GO:0005522=GO_REF:0000019, GO:0005938=GO_REF:0000039} O95466 Formin-like protein 1 protein 20130415 {GO:0005515=IPI, GO:0030036=IEA, GO:0005886=ISS, GO:0006929=IEA, GO:0008360=IMP, GO:0003779=IEA, GO:0005829=ISS, GO:0045335=ISS, GO:0032794=IDA, GO:0051014=ISS, GO:0003674=ND, GO:0048365=ISS, GO:0032059=IEA, GO:0051015=ISS, GO:0030866=IMP, GO:0005522=IEA, GO:0005938=IEA} actin cytoskeleton organization, actin filament severing, cortical actin cytoskeleton organization, regulation of cell shape, substrate-dependent cell migration bleb, cell cortex, cytosol, phagocytic vesicle, plasma membrane GTPase activating protein binding, Rac GTPase binding, actin binding, actin filament binding, molecular_function, profilin binding, protein binding Human UniProtKB:O75044 FMNL2 UniProtKB UniProtKB {GO:0005737=GO_REF:0000039, GO:0030036=GO_REF:0000002, GO:0030866=PMID:21834987, GO:0022604=PMID:21834987, GO:0007010=PMID:21834987, GO:0017048=GO_REF:0000002, GO:0003779=GO_REF:0000002} Q96PY5 Formin-like protein 2 protein 20110926 {GO:0005737=IEA, GO:0030036=IEA, GO:0030866=IMP, GO:0022604=IMP, GO:0007010=IMP, GO:0017048=IEA, GO:0003779=IEA} actin cytoskeleton organization, cortical actin cytoskeleton organization, cytoskeleton organization, regulation of cell morphogenesis cytoplasm Rho GTPase binding, actin binding Human FMNL3 UniProtKB UniProtKB {GO:0032794=GO_REF:0000024, GO:0005737=PMID:21834987, GO:0030036=GO_REF:0000002, GO:0016477=PMID:21834987, GO:0008360=PMID:21834987, GO:0007010=PMID:21834987, GO:0017048=GO_REF:0000002, GO:0003779=GO_REF:0000002} Q8IVF7 Formin-like protein 3 protein 20120606 {GO:0032794=ISS, GO:0005737=IDA, GO:0030036=IEA, GO:0016477=IMP, GO:0008360=IMP, GO:0007010=IMP, GO:0017048=IEA, GO:0003779=IEA} actin cytoskeleton organization, cell migration, cytoskeleton organization, regulation of cell shape cytoplasm GTPase activating protein binding, Rho GTPase binding, actin binding Human UniProtKB:Q6ZPF4 FMO1 ENSEMBL UniProtKB {GO:0050661=GO_REF:0000002, GO:0006805=Reactome:REACT_13705, GO:0050660=GO_REF:0000002, GO:0031227=GO_REF:0000002, GO:0006970=GO_REF:0000019, GO:0044281=Reactome:REACT_111217, GO:0006082=PMID:15144220, GO:0043231=GO_REF:0000019, GO:0070995=PMID:15144220, GO:0004497=PMID:1712018, GO:0004499=GO_REF:0000019, GO:0032496=GO_REF:0000019, GO:0005788=Reactome:REACT_13805, GO:0016021=GO_REF:0000037, GO:0009404=PMID:15144220} Q5QPT3 "Dimethylaniline monooxygenase ""N-oxide-forming"" 1" protein 20130413 {GO:0050661=IEA, GO:0006805=TAS, GO:0050660=IEA, GO:0031227=IEA, GO:0006970=IEA, GO:0044281=TAS, GO:0006082=IDA, GO:0043231=IEA, GO:0070995=IDA, GO:0004497=TAS, GO:0004499=IEA, GO:0032496=IEA, GO:0005788=TAS, GO:0016021=IEA, GO:0009404=IDA} NADPH oxidation, organic acid metabolic process, response to lipopolysaccharide, response to osmotic stress, small molecule metabolic process, toxin metabolic process, xenobiotic metabolic process endoplasmic reticulum lumen, integral to membrane, intracellular membrane-bounded organelle, intrinsic to endoplasmic reticulum membrane N,N-dimethylaniline monooxygenase activity, NADP binding, flavin adenine dinucleotide binding, monooxygenase activity Human Ensembl:ENSRNOP00000044613 FMO3 Reactome UniProtKB {GO:0050661=GO_REF:0000019, GO:0006805=Reactome:REACT_13705, GO:0034899=GO_REF:0000003, GO:0004499=Reactome:REACT_236, GO:0017144=GO_REF:0000019, GO:0050660=GO_REF:0000002, GO:0005789=Reactome:REACT_236, GO:0031227=GO_REF:0000002, GO:0044281=Reactome:REACT_111217, GO:0016021=GO_REF:0000037, GO:0016597=GO_REF:0000019, GO:0043231=PMID:9207220} P31513 "Dimethylaniline monooxygenase ""N-oxide-forming"" 3" protein 20120320 {GO:0050661=IEA, GO:0006805=TAS, GO:0034899=IEA, GO:0004499=TAS, GO:0017144=IEA, GO:0050660=IEA, GO:0005789=TAS, GO:0031227=IEA, GO:0044281=TAS, GO:0016021=IEA, GO:0016597=IEA, GO:0043231=TAS} drug metabolic process, small molecule metabolic process, xenobiotic metabolic process endoplasmic reticulum membrane, integral to membrane, intracellular membrane-bounded organelle, intrinsic to endoplasmic reticulum membrane N,N-dimethylaniline monooxygenase activity, NADP binding, amino acid binding, flavin adenine dinucleotide binding, trimethylamine monooxygenase activity Human FMO4 UniProtKB UniProtKB {GO:0050661=GO_REF:0000002, GO:0006805=GO_REF:0000029, GO:0004499=PMID:1417778, GO:0050660=GO_REF:0000002, GO:0031227=GO_REF:0000002, GO:0016021=GO_REF:0000037, GO:0043231=GO_REF:0000029} P31512 "Dimethylaniline monooxygenase ""N-oxide-forming"" 4" protein 20021104 {GO:0050661=IEA, GO:0006805=NAS, GO:0004499=NAS, GO:0050660=IEA, GO:0031227=IEA, GO:0016021=IEA, GO:0043231=NAS} xenobiotic metabolic process integral to membrane, intracellular membrane-bounded organelle, intrinsic to endoplasmic reticulum membrane N,N-dimethylaniline monooxygenase activity, NADP binding, flavin adenine dinucleotide binding Human FMOD Reactome UniProtKB {GO:0007181=PMID:8093006, GO:0018146=Reactome:REACT_121120, GO:0005975=Reactome:REACT_474, GO:0005796=Reactome:REACT_121317, GO:0042340=Reactome:REACT_121313, GO:0005578=GO_REF:0000039, GO:0005576=Reactome:REACT_121303, GO:0044281=Reactome:REACT_111217, GO:0030203=Reactome:REACT_121315, GO:0043202=Reactome:REACT_121303, GO:0042339=Reactome:REACT_121288} Q06828 Fibromodulin protein 20130301 {GO:0007181=TAS, GO:0018146=TAS, GO:0005975=TAS, GO:0005796=TAS, GO:0042340=TAS, GO:0005578=IEA, GO:0005576=TAS, GO:0044281=TAS, GO:0030203=TAS, GO:0043202=TAS, GO:0042339=TAS} carbohydrate metabolic process, glycosaminoglycan metabolic process, keratan sulfate biosynthetic process, keratan sulfate catabolic process, keratan sulfate metabolic process, small molecule metabolic process, transforming growth factor beta receptor complex assembly Golgi lumen, extracellular region, lysosomal lumen, proteinaceous extracellular matrix Human FMR1 InterPro UniProtKB {GO:0005515=PMID:11438699, GO:0071598=GO_REF:0000019, GO:0010494=GO_REF:0000019, GO:0003723=GO_REF:0000002, GO:0005730=PMID:16407062, GO:0045202=GO_REF:0000019, GO:0003729=PMID:7692601, GO:0007417=GO_REF:0000019, GO:0005737=PMID:16407062, GO:0043197=GO_REF:0000019, GO:0043198=GO_REF:0000019, GO:0042788=PMID:12837692, GO:0045947=GO_REF:0000024, GO:0005654=PMID:10888599, GO:0051028=GO_REF:0000037, GO:0005845=GO_REF:0000024} Q8IXW7 FMR1 protein protein 20130413 {GO:0005515=IPI, GO:0071598=IEA, GO:0010494=IEA, GO:0003723=IEA, GO:0005730=TAS, GO:0045202=IEA, GO:0003729=TAS, GO:0007417=IEA, GO:0005737=TAS, GO:0043197=IEA, GO:0043198=IEA, GO:0042788=TAS, GO:0045947=ISS, GO:0005654=TAS, GO:0051028=IEA, GO:0005845=ISS} central nervous system development, mRNA transport, negative regulation of translational initiation cytoplasm, cytoplasmic stress granule, dendritic shaft, dendritic spine, mRNA cap binding complex, neuronal ribonucleoprotein granule, nucleolus, nucleoplasm, polysomal ribosome, synapse RNA binding, mRNA binding, protein binding Human InterPro:IPR004087|InterPro:IPR004088 FN1 BHF-UCL UniProtKB {GO:0005515=PMID:2531657, GO:0008360=GO_REF:0000037, GO:0005518=PMID:3024962, GO:0050900=Reactome:REACT_12051, GO:0016324=GO_REF:0000019, GO:0030198=Reactome:REACT_118779, GO:0034446=PMID:16236823, GO:0031093=Reactome:REACT_21351, GO:0007155=PMID:1423622, GO:0008201=PMID:10075919, GO:0005793=PMID:15308636, GO:0005578=GO_REF:0000029, GO:0009611=PMID:7989369, GO:0030168=Reactome:REACT_798, GO:0005577=PMID:3997886, GO:0005576=Reactome:REACT_160174, GO:0006953=GO_REF:0000037, GO:0001525=GO_REF:0000037, GO:0005604=GO_REF:0000019, GO:0031012=PMID:22261194, GO:0016504=GO_REF:0000019, GO:0018149=PMID:3997886, GO:0016477=GO_REF:0000029, GO:0007161=GO_REF:0000019, GO:0007596=Reactome:REACT_604, GO:0002576=Reactome:REACT_318, GO:0007044=GO_REF:0000019, GO:0005201=GO_REF:0000029} P02751 Fibronectin protein 20110114 {GO:0005515=IPI, GO:0008360=IEA, GO:0005518=NAS, GO:0050900=TAS, GO:0016324=IEA, GO:0030198=TAS, GO:0034446=IDA, GO:0031093=TAS, GO:0007155=NAS, GO:0008201=NAS, GO:0005793=IDA, GO:0005578=NAS, GO:0009611=NAS, GO:0030168=TAS, GO:0005577=IDA, GO:0005576=TAS, GO:0006953=IEA, GO:0001525=IEA, GO:0005604=IEA, GO:0031012=ISS, GO:0016504=IEA, GO:0018149=IDA, GO:0016477=NAS, GO:0007161=IEA, GO:0007596=TAS, GO:0002576=TAS, GO:0007044=IEA, GO:0005201=NAS} acute-phase response, angiogenesis, blood coagulation, calcium-independent cell-matrix adhesion, cell adhesion, cell migration, cell-substrate junction assembly, extracellular matrix organization, leukocyte migration, peptide cross-linking, platelet activation, platelet degranulation, regulation of cell shape, response to wounding, substrate adhesion-dependent cell spreading apical plasma membrane, basement membrane, endoplasmic reticulum-Golgi intermediate compartment, extracellular matrix, extracellular region, fibrinogen complex, platelet alpha granule lumen, proteinaceous extracellular matrix collagen binding, extracellular matrix structural constituent, heparin binding, peptidase activator activity, protein binding Human UniProtKB:P08519 FN3KRP UniProtKB UniProtKB {GO:0016301=GO_REF:0000037, GO:0016772=GO_REF:0000002} Q9HA64 Ketosamine-3-kinase protein 20130413 {GO:0016301=IEA, GO:0016772=IEA} kinase activity, transferase activity, transferring phosphorus-containing groups Human UniProtKB-KW:KW-0418 FNBP1 IntAct UniProtKB {GO:0005515=PMID:20562859, GO:0005905=GO_REF:0000039, GO:0005886=GO_REF:0000039, GO:0016023=GO_REF:0000039, GO:0005856=GO_REF:0000039, GO:0005938=GO_REF:0000039, GO:0005764=GO_REF:0000039, GO:0042802=PMID:17512409, GO:0008289=GO_REF:0000037, GO:0006897=GO_REF:0000037} Q96RU3 Formin-binding protein 1 protein 20130415 {GO:0005515=IPI, GO:0005905=IEA, GO:0005886=IEA, GO:0016023=IEA, GO:0005856=IEA, GO:0005938=IEA, GO:0005764=IEA, GO:0042802=IPI, GO:0008289=IEA, GO:0006897=IEA} endocytosis cell cortex, coated pit, cytoplasmic membrane-bounded vesicle, cytoskeleton, lysosome, plasma membrane identical protein binding, lipid binding, protein binding Human UniProtKB:Q96RU3 FNBP1L BHF-UCL UniProtKB {GO:0005515=PMID:20730103, GO:0072583=PMID:20730103, GO:0005886=GO_REF:0000039, GO:0097320=PMID:20730103, GO:0006914=GO_REF:0000037, GO:0051491=PMID:20730103, GO:0006900=PMID:20730103, GO:0008289=GO_REF:0000037, GO:0016050=PMID:20730103, GO:0030050=PMID:20730103, GO:0016023=PMID:20730103, GO:0005856=GO_REF:0000039, GO:0005938=GO_REF:0000039, GO:0010324=PMID:20730103} Q5T0N5 Formin-binding protein 1-like protein 20120517 {GO:0005515=IPI, GO:0072583=IDA, GO:0005886=IEA, GO:0097320=IDA, GO:0006914=IEA, GO:0051491=IDA, GO:0006900=IDA, GO:0008289=IEA, GO:0016050=IDA, GO:0030050=IDA, GO:0016023=IDA, GO:0005856=IEA, GO:0005938=IEA, GO:0010324=IDA} autophagy, clathrin-mediated endocytosis, membrane budding, membrane invagination, membrane tubulation, positive regulation of filopodium assembly, vesicle organization, vesicle transport along actin filament cell cortex, cytoplasmic membrane-bounded vesicle, cytoskeleton, plasma membrane lipid binding, protein binding Human FNBP4 HPA UniProtKB {GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052} Q8N3X1 Formin-binding protein 4 protein 20111111 {GO:0005730=IDA, GO:0005634=IDA} nucleolus, nucleus NOT Human FNDC3A UniProtKB UniProtKB {GO:0012506=GO_REF:0000019, GO:0009566=GO_REF:0000019, GO:0016337=GO_REF:0000019, GO:0005794=PMID:18218838, GO:0060009=GO_REF:0000019, GO:0000139=GO_REF:0000039, GO:0001669=GO_REF:0000019, GO:0007286=GO_REF:0000019, GO:0016021=GO_REF:0000037, GO:0005829=GO_REF:0000019} Q9Y2H6 Fibronectin type-III domain-containing protein 3A protein 20090622 {GO:0012506=IEA, GO:0009566=IEA, GO:0016337=IEA, GO:0005794=IDA, GO:0060009=IEA, GO:0000139=IEA, GO:0001669=IEA, GO:0007286=IEA, GO:0016021=IEA, GO:0005829=IEA} Sertoli cell development, cell-cell adhesion, fertilization, spermatid development Golgi apparatus, Golgi membrane, acrosomal vesicle, cytosol, integral to membrane, vesicle membrane Human FNDC3B HPA UniProtKB {GO:0005783=GO_REF:0000052, GO:0045600=GO_REF:0000019, GO:0016021=GO_REF:0000037} Q53EP0 Fibronectin type III domain-containing protein 3B protein 20080205 {GO:0005783=IDA, GO:0045600=IEA, GO:0016021=IEA} positive regulation of fat cell differentiation endoplasmic reticulum, integral to membrane Human FNDC4 UniProtKB UniProtKB {GO:0005886=GO_REF:0000024, GO:0005783=GO_REF:0000024, GO:0016021=GO_REF:0000037} Q9H6D8 Fibronectin type III domain-containing protein 4 protein 20120423 {GO:0005886=ISS, GO:0005783=ISS, GO:0016021=IEA} endoplasmic reticulum, integral to membrane, plasma membrane Human UniProtKB:Q3TR08 FNDC5 UniProtKB UniProtKB {GO:0003674=GO_REF:0000015, GO:0008150=GO_REF:0000015, GO:0005886=GO_REF:0000024, GO:0005179=GO_REF:0000037, GO:0005783=GO_REF:0000024, GO:0014850=GO_REF:0000024, GO:0005576=GO_REF:0000024, GO:0016021=GO_REF:0000037, GO:0090336=GO_REF:0000024, GO:0005778=GO_REF:0000039} Q8NAU1 Fibronectin type III domain-containing protein 5 protein 20120517 {GO:0003674=ND, GO:0008150=ND, GO:0005886=ISS, GO:0005179=IEA, GO:0005783=ISS, GO:0014850=ISS, GO:0005576=ISS, GO:0016021=IEA, GO:0090336=ISS, GO:0005778=IEA} biological_process, positive regulation of brown fat cell differentiation, response to muscle activity endoplasmic reticulum, extracellular region, integral to membrane, peroxisomal membrane, plasma membrane hormone activity, molecular_function Human FNDC7 UniProtKB UniProtKB {GO:0005576=GO_REF:0000039} Q5VTL7 Fibronectin type III domain-containing protein 7 protein 20130413 {GO:0005576=IEA} extracellular region Human UniProtKB-SubCell:SL-0243 FNIP1 IntAct UniProtKB {GO:0031929=PMID:17028174, GO:0005515=PMID:22190034, GO:0051056=GO_REF:0000002, GO:0032007=GO_REF:0000024, GO:0007264=GO_REF:0000002, GO:0005622=GO_REF:0000002, GO:0005085=GO_REF:0000038, GO:2000973=GO_REF:0000024, GO:0005737=PMID:17028174, GO:0002904=GO_REF:0000024, GO:0001932=PMID:18663353, GO:0002327=GO_REF:0000024, GO:0043154=GO_REF:0000024, GO:0009267=GO_REF:0000024} Q8TF40 Folliculin-interacting protein 1 protein 20130415 {GO:0031929=IMP, GO:0005515=IPI, GO:0051056=IEA, GO:0032007=ISS, GO:0007264=IEA, GO:0005622=IEA, GO:0005085=IEA, GO:2000973=ISS, GO:0005737=IDA, GO:0002904=ISS, GO:0001932=IDA, GO:0002327=ISS, GO:0043154=ISS, GO:0009267=ISS} TOR signaling cascade, cellular response to starvation, immature B cell differentiation, negative regulation of TOR signaling cascade, negative regulation of cysteine-type endopeptidase activity involved in apoptotic process, positive regulation of B cell apoptotic process, regulation of pro-B cell differentiation, regulation of protein phosphorylation, regulation of small GTPase mediated signal transduction, small GTPase mediated signal transduction cytoplasm, intracellular guanyl-nucleotide exchange factor activity, protein binding Human UniProtKB:Q9Q2G4 FNTA BHF-UCL UniProtKB {GO:0018343=PMID:19228685, GO:0008017=PMID:19228685, GO:0005515=PMID:15451670, GO:0018342=GO_REF:0000002, GO:0030971=GO_REF:0000019, GO:0018344=PMID:8106351, GO:0043014=PMID:19228685, GO:0005875=PMID:19228685, GO:0006915=Reactome:REACT_578, GO:0045213=GO_REF:0000019, GO:0006921=Reactome:REACT_995, GO:0005829=Reactome:REACT_12014, GO:0004660=PMID:19228685, GO:0004661=PMID:8106351, GO:0005737=PMID:8599089, GO:0090045=PMID:19228685, GO:0030548=GO_REF:0000019, GO:0004662=GO_REF:0000003, GO:0004663=GO_REF:0000019, GO:0090044=PMID:19228685, GO:0007179=PMID:8599089, GO:0008318=GO_REF:0000002} P49354 Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha protein 20090724 {GO:0018343=IDA, GO:0008017=IDA, GO:0005515=IPI, GO:0018342=IEA, GO:0030971=IEA, GO:0018344=TAS, GO:0043014=IDA, GO:0005875=IDA, GO:0006915=TAS, GO:0045213=IEA, GO:0006921=TAS, GO:0005829=TAS, GO:0004660=IDA, GO:0004661=TAS, GO:0005737=TAS, GO:0090045=IDA, GO:0030548=IEA, GO:0004662=IEA, GO:0004663=IEA, GO:0090044=IDA, GO:0007179=TAS, GO:0008318=IEA} apoptotic process, cellular component disassembly involved in execution phase of apoptosis, neurotransmitter receptor metabolic process, positive regulation of deacetylase activity, positive regulation of tubulin deacetylation, protein farnesylation, protein geranylgeranylation, protein prenylation, transforming growth factor beta receptor signaling pathway cytoplasm, cytosol, microtubule associated complex CAAX-protein geranylgeranyltransferase activity, Rab geranylgeranyltransferase activity, acetylcholine receptor regulator activity, alpha-tubulin binding, microtubule binding, protein binding, protein farnesyltransferase activity, protein geranylgeranyltransferase activity, protein prenyltransferase activity, receptor tyrosine kinase binding contributes_to Human FNTB BHF-UCL UniProtKB {GO:0004660=PMID:19228685, GO:0005515=PMID:15451670, GO:0018343=PMID:19228685, GO:0005875=PMID:19228685, GO:0042127=GO_REF:0000002, GO:0005965=GO_REF:0000002, GO:0046872=GO_REF:0000037} P49356 Protein farnesyltransferase subunit beta protein 20090724 {GO:0004660=IDA, GO:0005515=IPI, GO:0018343=IDA, GO:0005875=IDA, GO:0042127=IEA, GO:0005965=IEA, GO:0046872=IEA} protein farnesylation, regulation of cell proliferation microtubule associated complex, protein farnesyltransferase complex metal ion binding, protein binding, protein farnesyltransferase activity Human FOLH1 HPA UniProtKB {GO:0005737=GO_REF:0000052, GO:0006760=GO_REF:0000019, GO:0016020=PMID:9375657, GO:0005887=GO_REF:0000019, GO:0006508=PMID:9375657, GO:0004180=GO_REF:0000019, GO:0005634=GO_REF:0000052, GO:0008233=PMID:9375657, GO:0016805=GO_REF:0000019, GO:0046872=GO_REF:0000037, GO:0008237=GO_REF:0000037} Q04609 Glutamate carboxypeptidase 2 protein 20080205 {GO:0005737=IDA, GO:0006760=IEA, GO:0016020=NAS, GO:0005887=IEA, GO:0006508=NAS, GO:0004180=IEA, GO:0005634=IDA, GO:0008233=NAS, GO:0016805=IEA, GO:0046872=IEA, GO:0008237=IEA} folic acid-containing compound metabolic process, proteolysis cytoplasm, integral to plasma membrane, membrane, nucleus carboxypeptidase activity, dipeptidase activity, metal ion binding, metallopeptidase activity, peptidase activity Human FOLR1 PINC UniProtKB {GO:0008219=GO_REF:0000037, GO:0005542=PMID:1840502, GO:0016020=PMID:2768245, GO:0005886=PMID:1840502, GO:0005887=PMID:10633085, GO:0015884=PMID:9545095, GO:0004872=PMID:10633085, GO:0005576=GO_REF:0000039, GO:0046655=GO_REF:0000019, GO:0031225=GO_REF:0000037, GO:0006898=PMID:9545095} P15328 Folate receptor alpha protein 20030904 {GO:0008219=IEA, GO:0005542=NAS, GO:0016020=TAS, GO:0005886=NAS, GO:0005887=TAS, GO:0015884=TAS, GO:0004872=TAS, GO:0005576=IEA, GO:0046655=IEA, GO:0031225=IEA, GO:0006898=TAS} cell death, folic acid metabolic process, folic acid transport, receptor-mediated endocytosis anchored to membrane, extracellular region, integral to plasma membrane, membrane, plasma membrane folic acid binding, receptor activity Human FOLR2 PINC UniProtKB {GO:0005542=GO_REF:0000037, GO:0016020=PMID:2605182, GO:0005886=GO_REF:0000039, GO:0015884=PMID:2605182, GO:0005576=GO_REF:0000039, GO:0031225=GO_REF:0000037} P14207 Folate receptor beta protein 20030904 {GO:0005542=IEA, GO:0016020=TAS, GO:0005886=IEA, GO:0015884=TAS, GO:0005576=IEA, GO:0031225=IEA} folic acid transport anchored to membrane, extracellular region, membrane, plasma membrane folic acid binding Human FOLR3 PINC UniProtKB {GO:0005542=GO_REF:0000037, GO:0016020=PMID:8110752, GO:0015884=PMID:8110752, GO:0005576=GO_REF:0000039, GO:0019898=PMID:8110752} P41439 Folate receptor gamma protein 20030904 {GO:0005542=IEA, GO:0016020=TAS, GO:0015884=TAS, GO:0005576=IEA, GO:0019898=TAS} folic acid transport extracellular region, extrinsic to membrane, membrane folic acid binding Human FOPNL HPA UniProtKB {GO:0042384=PMID:15616553, GO:0005813=GO_REF:0000052, GO:0034453=GO_REF:0000002, GO:0005815=GO_REF:0000002, GO:0031514=GO_REF:0000024, GO:0034451=PMID:15616553, GO:0005634=GO_REF:0000052, GO:0005932=GO_REF:0000024} Q96NB1 LisH domain-containing protein FOPNL protein 20111111 {GO:0042384=IMP, GO:0005813=IDA, GO:0034453=IEA, GO:0005815=IEA, GO:0031514=ISS, GO:0034451=IDA, GO:0005634=IDA, GO:0005932=ISS} cilium assembly, microtubule anchoring centriolar satellite, centrosome, microtubule basal body, microtubule organizing center, motile cilium, nucleus Human FOS HPA UniProtKB {GO:0005515=PMID:20936779, GO:0003700=PMID:9732876, GO:0044212=PMID:9732876, GO:0006366=GO_REF:0000019, GO:0009409=GO_REF:0000019, GO:0051591=GO_REF:0000019, GO:0051403=Reactome:REACT_21308, GO:0002756=Reactome:REACT_6809, GO:0003690=GO_REF:0000019, GO:0031668=GO_REF:0000019, GO:0002755=Reactome:REACT_27215, GO:0032496=GO_REF:0000019, GO:0007179=PMID:9732876, GO:0009416=GO_REF:0000019, GO:0001661=GO_REF:0000019, GO:0051412=GO_REF:0000019, GO:0007565=GO_REF:0000019, GO:0038124=Reactome:REACT_8006, GO:0038123=Reactome:REACT_8005, GO:0034134=Reactome:REACT_7980, GO:0007568=GO_REF:0000019, GO:0009636=GO_REF:0000019, GO:0030431=GO_REF:0000019, GO:0002224=Reactome:REACT_9020, GO:0009629=GO_REF:0000019, GO:0045087=Reactome:REACT_6802, GO:0032570=GO_REF:0000019, GO:0005654=Reactome:REACT_21404, GO:0034166=Reactome:REACT_9027, GO:0035666=Reactome:REACT_25281, GO:0045893=PMID:9732876, GO:0034162=Reactome:REACT_9047, GO:0008134=GO_REF:0000019, GO:0043005=GO_REF:0000019, GO:0034142=Reactome:REACT_6894, GO:0005634=GO_REF:0000052, GO:0060395=PMID:9732876, GO:0032870=GO_REF:0000019, GO:0051090=Reactome:REACT_21326, GO:0006954=PMID:9443941, GO:0045944=GO_REF:0000019, GO:0071277=GO_REF:0000019, GO:0034097=GO_REF:0000019, GO:0034138=Reactome:REACT_6783, GO:0005667=GO_REF:0000019, GO:0006357=PMID:10918580, GO:0042493=GO_REF:0000019, GO:0005730=GO_REF:0000052, GO:0070412=PMID:9732876, GO:0003677=GO_REF:0000002, GO:0007399=GO_REF:0000019, GO:0009612=GO_REF:0000019, GO:0043565=GO_REF:0000019, GO:0006306=PMID:9888853, GO:0016020=GO_REF:0000019, GO:0034614=PMID:17217916, GO:0034146=Reactome:REACT_9061} P01100 Proto-oncogene c-Fos protein 20081203 {GO:0005515=IPI, GO:0003700=IDA, GO:0044212=IDA, GO:0006366=IEA, GO:0009409=IEA, GO:0051591=IEA, GO:0051403=TAS, GO:0002756=TAS, GO:0003690=IEA, GO:0031668=IEA, GO:0002755=TAS, GO:0032496=IEA, GO:0007179=IDA, GO:0009416=IEA, GO:0001661=IEA, GO:0051412=IEA, GO:0007565=IEA, GO:0038124=TAS, GO:0038123=TAS, GO:0034134=TAS, GO:0007568=IEA, GO:0009636=IEA, GO:0030431=IEA, GO:0002224=TAS, GO:0009629=IEA, GO:0045087=TAS, GO:0032570=IEA, GO:0005654=TAS, GO:0034166=TAS, GO:0035666=TAS, GO:0045893=IDA, GO:0034162=TAS, GO:0008134=IEA, GO:0043005=IEA, GO:0034142=TAS, GO:0005634=IDA, GO:0060395=IDA, GO:0032870=IEA, GO:0051090=TAS, GO:0006954=TAS, GO:0045944=IEA, GO:0071277=IEA, GO:0034097=IEA, GO:0034138=TAS, GO:0005667=IEA, GO:0006357=TAS, GO:0042493=IEA, GO:0005730=IDA, GO:0070412=IPI, GO:0003677=IEA, GO:0007399=IEA, GO:0009612=IEA, GO:0043565=IEA, GO:0006306=TAS, GO:0016020=IEA, GO:0034614=IDA, GO:0034146=TAS} DNA methylation, MyD88-dependent toll-like receptor signaling pathway, MyD88-independent toll-like receptor signaling pathway, SMAD protein signal transduction, TRIF-dependent toll-like receptor signaling pathway, aging, cellular response to calcium ion, cellular response to extracellular stimulus, cellular response to hormone stimulus, cellular response to reactive oxygen species, conditioned taste aversion, female pregnancy, inflammatory response, innate immune response, nervous system development, positive regulation of transcription from RNA polymerase II promoter, positive regulation of transcription, DNA-dependent, regulation of sequence-specific DNA binding transcription factor activity, regulation of transcription from RNA polymerase II promoter, response to cAMP, response to cold, response to corticosterone stimulus, response to cytokine stimulus, response to drug, response to gravity, response to light stimulus, response to lipopolysaccharide, response to mechanical stimulus, response to progesterone stimulus, response to toxic substance, sleep, stress-activated MAPK cascade, toll-like receptor 10 signaling pathway, toll-like receptor 2 signaling pathway, toll-like receptor 3 signaling pathway, toll-like receptor 4 signaling pathway, toll-like receptor 5 signaling pathway, toll-like receptor 9 signaling pathway, toll-like receptor TLR1:TLR2 signaling pathway, toll-like receptor TLR6:TLR2 signaling pathway, toll-like receptor signaling pathway, transcription from RNA polymerase II promoter, transforming growth factor beta receptor signaling pathway membrane, neuron projection, nucleolus, nucleoplasm, nucleus, transcription factor complex DNA binding, R-SMAD binding, double-stranded DNA binding, protein binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, transcription factor binding, transcription regulatory region DNA binding NOT Human FOSB ENSEMBL UniProtKB {GO:0043565=GO_REF:0000002, GO:0003700=GO_REF:0000002, GO:0071277=GO_REF:0000019, GO:0007610=PMID:8706134, GO:0007275=PMID:8706134, GO:0005634=GO_REF:0000002, GO:0000122=PMID:1900040, GO:0003677=PMID:1900040, GO:0008134=PMID:1900040} Q49AD7 FOSB protein protein 20130413 {GO:0043565=IEA, GO:0003700=IEA, GO:0071277=IEA, GO:0007610=TAS, GO:0007275=TAS, GO:0005634=IEA, GO:0000122=TAS, GO:0003677=TAS, GO:0008134=TAS} behavior, cellular response to calcium ion, multicellular organismal development, negative regulation of transcription from RNA polymerase II promoter nucleus DNA binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, transcription factor binding Human Ensembl:ENSMUSP00000003640 FOSL1 IntAct UniProtKB {GO:0005515=PMID:19060904, GO:0042542=GO_REF:0000019, GO:0043005=GO_REF:0000019, GO:0008284=PMID:8230424, GO:0008285=GO_REF:0000019, GO:0003700=GO_REF:0000002, GO:0060674=GO_REF:0000019, GO:0006366=PMID:2107490, GO:0005634=GO_REF:0000039, GO:0051591=GO_REF:0000019, GO:0005829=GO_REF:0000019, GO:0051091=GO_REF:0000019, GO:0006935=PMID:10918580, GO:0031668=GO_REF:0000019, GO:0007612=GO_REF:0000019, GO:0034097=GO_REF:0000019, GO:0051412=GO_REF:0000019, GO:0007565=GO_REF:0000019, GO:0000977=GO_REF:0000019, GO:0043065=GO_REF:0000019, GO:0006357=PMID:10918580, GO:0042493=GO_REF:0000019, GO:0009615=PMID:8230424, GO:0003677=GO_REF:0000002, GO:0045787=GO_REF:0000019, GO:0001701=GO_REF:0000019, GO:0009612=GO_REF:0000019, GO:0007296=GO_REF:0000019, GO:0042734=GO_REF:0000019, GO:0006968=PMID:10918580, GO:0009629=GO_REF:0000019, GO:0032570=GO_REF:0000019} P15407 Fos-related antigen 1 protein 20130415 {GO:0005515=IPI, GO:0042542=IEA, GO:0043005=IEA, GO:0008284=TAS, GO:0008285=IEA, GO:0003700=IEA, GO:0060674=IEA, GO:0006366=TAS, GO:0005634=IEA, GO:0051591=IEA, GO:0005829=IEA, GO:0051091=IEA, GO:0006935=TAS, GO:0031668=IEA, GO:0007612=IEA, GO:0034097=IEA, GO:0051412=IEA, GO:0007565=IEA, GO:0000977=IEA, GO:0043065=IEA, GO:0006357=TAS, GO:0042493=IEA, GO:0009615=TAS, GO:0003677=IEA, GO:0045787=IEA, GO:0001701=IEA, GO:0009612=IEA, GO:0007296=IEA, GO:0042734=IEA, GO:0006968=TAS, GO:0009629=IEA, GO:0032570=IEA} cellular defense response, cellular response to extracellular stimulus, chemotaxis, female pregnancy, in utero embryonic development, learning, negative regulation of cell proliferation, placenta blood vessel development, positive regulation of apoptotic process, positive regulation of cell cycle, positive regulation of cell proliferation, positive regulation of sequence-specific DNA binding transcription factor activity, regulation of transcription from RNA polymerase II promoter, response to cAMP, response to corticosterone stimulus, response to cytokine stimulus, response to drug, response to gravity, response to hydrogen peroxide, response to mechanical stimulus, response to progesterone stimulus, response to virus, transcription from RNA polymerase II promoter, vitellogenesis cytosol, neuron projection, nucleus, presynaptic membrane DNA binding, RNA polymerase II regulatory region sequence-specific DNA binding, protein binding, sequence-specific DNA binding transcription factor activity Human UniProtKB:O95751 FOSL2 HPA UniProtKB {GO:0008219=PMID:8954781, GO:0000977=GO_REF:0000019, GO:0003700=GO_REF:0000002, GO:0006357=PMID:8954781, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0048146=GO_REF:0000019, GO:0006351=GO_REF:0000037} P15408 Fos-related antigen 2 protein 20090616 {GO:0008219=TAS, GO:0000977=IEA, GO:0003700=IEA, GO:0006357=TAS, GO:0005730=IDA, GO:0005634=IDA, GO:0048146=IEA, GO:0006351=IEA} cell death, positive regulation of fibroblast proliferation, regulation of transcription from RNA polymerase II promoter, transcription, DNA-dependent nucleolus, nucleus RNA polymerase II regulatory region sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity NOT Human FOXA1 BHF-UCL UniProtKB {GO:0007389=GO_REF:0000033, GO:0003700=PMID:8652662, GO:0044212=PMID:16087863, GO:0003705=GO_REF:0000033, GO:2000049=PMID:20160041, GO:0005634=PMID:20160041, GO:0010719=PMID:20160041, GO:0009790=GO_REF:0000033, GO:0010817=GO_REF:0000033, GO:0051091=PMID:16087863, GO:0003690=GO_REF:0000033, GO:0045944=PMID:20160041, GO:0006338=GO_REF:0000024, GO:0060738=GO_REF:0000033, GO:0032355=PMID:16087863, GO:0060528=GO_REF:0000033, GO:0005667=GO_REF:0000033, GO:0060743=GO_REF:0000033, GO:0008301=GO_REF:0000033, GO:0019904=GO_REF:0000033, GO:0060741=GO_REF:0000033, GO:0060740=GO_REF:0000033, GO:0048665=GO_REF:0000033, GO:0042593=GO_REF:0000033, GO:0003677=PMID:9931457, GO:0043565=GO_REF:0000019, GO:0001077=GO_REF:0000024, GO:0045931=PMID:16087863, GO:0060441=GO_REF:0000033, GO:0045666=GO_REF:0000033, GO:0060487=GO_REF:0000033, GO:0033148=PMID:16087863, GO:0042445=GO_REF:0000019, GO:0008134=GO_REF:0000033} P55317 Hepatocyte nuclear factor 3-alpha protein 20110311 {GO:0007389=IBA, GO:0003700=TAS, GO:0044212=IDA, GO:0003705=IBA, GO:2000049=IC, GO:0005634=IDA, GO:0010719=IMP, GO:0009790=IBA, GO:0010817=IBA, GO:0051091=IMP, GO:0003690=IBA, GO:0045944=IDA, GO:0006338=ISS, GO:0060738=IBA, GO:0032355=IDA, GO:0060528=IBA, GO:0005667=IBA, GO:0060743=IBA, GO:0008301=IBA, GO:0019904=IBA, GO:0060741=IBA, GO:0060740=IBA, GO:0048665=IBA, GO:0042593=IBA, GO:0003677=IDA, GO:0043565=IEA, GO:0001077=ISS, GO:0045931=IMP, GO:0060441=IBA, GO:0045666=IBA, GO:0060487=IBA, GO:0033148=IMP, GO:0042445=IEA, GO:0008134=IBA} chromatin remodeling, embryo development, epithelial cell maturation involved in prostate gland development, epithelial tube branching involved in lung morphogenesis, epithelial-mesenchymal signaling involved in prostate gland development, glucose homeostasis, hormone metabolic process, lung epithelial cell differentiation, negative regulation of epithelial to mesenchymal transition, neuron fate specification, pattern specification process, positive regulation of cell-cell adhesion mediated by cadherin, positive regulation of intracellular estrogen receptor signaling pathway, positive regulation of mitotic cell cycle, positive regulation of neuron differentiation, positive regulation of sequence-specific DNA binding transcription factor activity, positive regulation of transcription from RNA polymerase II promoter, prostate gland epithelium morphogenesis, prostate gland stromal morphogenesis, regulation of hormone levels, response to estradiol stimulus, secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development nucleus, transcription factor complex DNA binding, DNA binding, bending, RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription, RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity, double-stranded DNA binding, protein domain specific binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, transcription factor binding, transcription regulatory region DNA binding Human UniProtKB:P23512 FOXA2 BHF-UCL UniProtKB {GO:0003700=PMID:12124776, GO:0044212=PMID:15737987, GO:0003705=GO_REF:0000033, GO:2000049=PMID:20160041, GO:0003690=GO_REF:0000033, GO:0000433=GO_REF:0000024, GO:0000432=GO_REF:0000024, GO:0001705=GO_REF:0000033, GO:0008301=GO_REF:0000033, GO:0023019=GO_REF:0000019, GO:0019904=GO_REF:0000033, GO:0000978=PMID:12642491, GO:0001701=GO_REF:0000033, GO:0060441=GO_REF:0000033, GO:0060487=GO_REF:0000033, GO:0070741=PMID:15737987, GO:0045893=GO_REF:0000024, GO:0008134=GO_REF:0000033, GO:0021533=GO_REF:0000033, GO:0008344=GO_REF:0000019, GO:0005634=PMID:20160041, GO:0010719=PMID:20160041, GO:0009952=GO_REF:0000033, GO:0043433=PMID:12642491, GO:0051090=GO_REF:0000033, GO:0005737=GO_REF:0000039, GO:0032525=GO_REF:0000019, GO:0045944=PMID:20160041, GO:0045945=GO_REF:0000019, GO:0040019=GO_REF:0000024, GO:0021904=GO_REF:0000033, GO:0021779=GO_REF:0000033, GO:0005667=GO_REF:0000033, GO:0006357=PMID:12911579, GO:0090009=GO_REF:0000024, GO:2000543=GO_REF:0000024, GO:0048665=GO_REF:0000033, GO:0033132=GO_REF:0000024, GO:0032289=GO_REF:0000033, GO:0003677=PMID:9931457, GO:0030193=PMID:12911579, GO:0045665=GO_REF:0000033, GO:0007492=GO_REF:0000033, GO:0045666=GO_REF:0000033, GO:0031018=PMID:12124776, GO:0071542=GO_REF:0000019, GO:2000971=GO_REF:0000024, GO:2000976=GO_REF:0000024, GO:0061178=GO_REF:0000024, GO:0016568=GO_REF:0000037} Q9Y261 Hepatocyte nuclear factor 3-beta protein 20110808 {GO:0003700=IDA, GO:0044212=IMP, GO:0003705=IBA, GO:2000049=IC, GO:0003690=IBA, GO:0000433=ISS, GO:0000432=ISS, GO:0001705=IBA, GO:0008301=IBA, GO:0023019=IEA, GO:0019904=IBA, GO:0000978=IDA, GO:0001701=IBA, GO:0060441=IBA, GO:0060487=IBA, GO:0070741=TAS, GO:0045893=ISS, GO:0008134=IBA, GO:0021533=IBA, GO:0008344=IEA, GO:0005634=IDA, GO:0010719=IMP, GO:0009952=IBA, GO:0043433=IMP, GO:0051090=IBA, GO:0005737=IEA, GO:0032525=IEA, GO:0045944=IDA, GO:0045945=IEA, GO:0040019=ISS, GO:0021904=IBA, GO:0021779=IBA, GO:0005667=IBA, GO:0006357=IDA, GO:0090009=ISS, GO:2000543=ISS, GO:0048665=IBA, GO:0033132=ISS, GO:0032289=IBA, GO:0003677=IDA, GO:0030193=IDA, GO:0045665=IBA, GO:0007492=IBA, GO:0045666=IBA, GO:0031018=IDA, GO:0071542=IEA, GO:2000971=ISS, GO:2000976=ISS, GO:0061178=ISS, GO:0016568=IEA} adult locomotory behavior, anterior/posterior pattern specification, cell differentiation in hindbrain, central nervous system myelin formation, chromatin modification, dopaminergic neuron differentiation, dorsal/ventral neural tube patterning, ectoderm formation, endocrine pancreas development, endoderm development, epithelial tube branching involved in lung morphogenesis, in utero embryonic development, lung epithelial cell differentiation, negative regulation of detection of glucose, negative regulation of epithelial to mesenchymal transition, negative regulation of glucokinase activity, negative regulation of neuron differentiation, negative regulation of sequence-specific DNA binding transcription factor activity, negative regulation of transcription from RNA polymerase II promoter by glucose, neuron fate specification, oligodendrocyte cell fate commitment, positive regulation of cell-cell adhesion mediated by cadherin, positive regulation of embryonic development, positive regulation of gastrulation, positive regulation of neuron differentiation, positive regulation of transcription from RNA polymerase II promoter, positive regulation of transcription from RNA polymerase II promoter by glucose, positive regulation of transcription from RNA polymerase III promoter, positive regulation of transcription, DNA-dependent, primitive streak formation, regulation of blood coagulation, regulation of insulin secretion involved in cellular response to glucose stimulus, regulation of sequence-specific DNA binding transcription factor activity, regulation of transcription from RNA polymerase II promoter, regulation of transcription from RNA polymerase II promoter involved in detection of glucose, response to interleukin-6, signal transduction involved in regulation of gene expression, somite rostral/caudal axis specification cytoplasm, nucleus, transcription factor complex DNA binding, DNA binding, bending, RNA polymerase II core promoter proximal region sequence-specific DNA binding, RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity, double-stranded DNA binding, protein domain specific binding, sequence-specific DNA binding transcription factor activity, transcription factor binding, transcription regulatory region DNA binding Human UniProtKB:P35583 FOXA3 Reactome UniProtKB {GO:0008285=GO_REF:0000033, GO:0003700=PMID:9369482, GO:0001678=PMID:9369482, GO:0044212=PMID:9369482, GO:0003705=GO_REF:0000033, GO:0005634=PMID:7739897, GO:0007283=GO_REF:0000019, GO:0009790=GO_REF:0000033, GO:0051090=GO_REF:0000033, GO:0003690=GO_REF:0000033, GO:0045944=PMID:12695546, GO:0009267=GO_REF:0000033, GO:0005667=GO_REF:0000033, GO:0008301=GO_REF:0000033, GO:0019904=GO_REF:0000033, GO:0048665=GO_REF:0000033, GO:0021999=GO_REF:0000033, GO:0043565=GO_REF:0000019, GO:0070368=GO_REF:0000033, GO:0060441=GO_REF:0000033, GO:0007420=GO_REF:0000033, GO:0031018=Reactome:REACT_13819, GO:0060487=GO_REF:0000033, GO:0016568=GO_REF:0000037, GO:0008134=GO_REF:0000033} P55318 Hepatocyte nuclear factor 3-gamma protein 20130301 {GO:0008285=IBA, GO:0003700=TAS, GO:0001678=TAS, GO:0044212=IMP, GO:0003705=IBA, GO:0005634=TAS, GO:0007283=IEA, GO:0009790=IBA, GO:0051090=IBA, GO:0003690=IBA, GO:0045944=IDA, GO:0009267=IBA, GO:0005667=IBA, GO:0008301=IBA, GO:0019904=IBA, GO:0048665=IBA, GO:0021999=IBA, GO:0043565=IEA, GO:0070368=IBA, GO:0060441=IRD, GO:0007420=IBA, GO:0031018=TAS, GO:0060487=IRD, GO:0016568=IEA, GO:0008134=IBA} brain development, cellular glucose homeostasis, cellular response to starvation, chromatin modification, embryo development, endocrine pancreas development, epithelial tube branching involved in lung morphogenesis, lung epithelial cell differentiation, negative regulation of cell proliferation, neural plate anterior/posterior regionalization, neuron fate specification, positive regulation of hepatocyte differentiation, positive regulation of transcription from RNA polymerase II promoter, regulation of sequence-specific DNA binding transcription factor activity, spermatogenesis nucleus, transcription factor complex DNA binding, bending, RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity, double-stranded DNA binding, protein domain specific binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, transcription factor binding, transcription regulatory region DNA binding Human FOXB1 UniProtKB UniProtKB {GO:0007389=GO_REF:0000033, GO:0021510=GO_REF:0000019, GO:0033504=GO_REF:0000024, GO:0061379=GO_REF:0000024, GO:0003705=GO_REF:0000033, GO:0001756=GO_REF:0000024, GO:0001655=GO_REF:0000019, GO:0005634=GO_REF:0000024, GO:0061377=GO_REF:0000024, GO:0009790=GO_REF:0000033, GO:0061374=GO_REF:0000024, GO:0021794=GO_REF:0000019, GO:0051090=GO_REF:0000033, GO:0022029=GO_REF:0000024, GO:0007412=GO_REF:0000024, GO:0043524=GO_REF:0000024, GO:0061381=GO_REF:0000024, GO:0003690=GO_REF:0000033, GO:0009888=GO_REF:0000033, GO:0005667=GO_REF:0000033, GO:0008301=GO_REF:0000033, GO:0021855=GO_REF:0000024, GO:0021767=GO_REF:0000024, GO:0043565=GO_REF:0000024, GO:0007595=GO_REF:0000024, GO:0007420=GO_REF:0000033, GO:0008542=GO_REF:0000024, GO:0030901=GO_REF:0000024, GO:0061030=GO_REF:0000024, GO:0008134=GO_REF:0000033} Q99853 Forkhead box protein B1 protein 20101123 {GO:0007389=IBA, GO:0021510=IEA, GO:0033504=ISS, GO:0061379=ISS, GO:0003705=IBA, GO:0001756=ISS, GO:0001655=IEA, GO:0005634=ISS, GO:0061377=ISS, GO:0009790=IBA, GO:0061374=ISS, GO:0021794=IEA, GO:0051090=IBA, GO:0022029=ISS, GO:0007412=ISS, GO:0043524=ISS, GO:0061381=ISS, GO:0003690=IBA, GO:0009888=IBA, GO:0005667=IBA, GO:0008301=IBA, GO:0021855=ISS, GO:0021767=ISS, GO:0043565=ISS, GO:0007595=ISS, GO:0007420=IBA, GO:0008542=ISS, GO:0030901=ISS, GO:0061030=ISS, GO:0008134=IBA} axon target recognition, brain development, cell migration in diencephalon, embryo development, epithelial cell differentiation involved in mammary gland alveolus development, floor plate development, hypothalamus cell migration, inferior colliculus development, lactation, mammary gland lobule development, mammillary body development, mammillothalamic axonal tract development, midbrain development, negative regulation of neuron apoptotic process, pattern specification process, regulation of sequence-specific DNA binding transcription factor activity, somitogenesis, spinal cord development, telencephalon cell migration, thalamus development, tissue development, urogenital system development, visual learning nucleus, transcription factor complex DNA binding, bending, RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity, double-stranded DNA binding, sequence-specific DNA binding, transcription factor binding Human UniProtKB:Q64732 FOXC1 BHF-UCL UniProtKB {GO:0001656=GO_REF:0000033, GO:0005515=PMID:22190034, GO:0001657=GO_REF:0000033, GO:0003700=PMID:11179011, GO:0044212=GO_REF:0000024, GO:0055010=GO_REF:0000033, GO:0003705=GO_REF:0000033, GO:0001756=GO_REF:0000033, GO:0001654=PMID:9792859, GO:0048844=GO_REF:0000033, GO:0007507=PMID:10474162, GO:0001946=GO_REF:0000033, GO:0014034=GO_REF:0000033, GO:0003690=GO_REF:0000033, GO:0050880=GO_REF:0000033, GO:0007219=GO_REF:0000033, GO:0014032=GO_REF:0000019, GO:0030199=GO_REF:0000033, GO:0030203=GO_REF:0000033, GO:0008301=PMID:7957066, GO:0001701=GO_REF:0000019, GO:0031490=GO_REF:0000033, GO:0060038=GO_REF:0000033, GO:0001501=GO_REF:0000019, GO:0005720=PMID:15684392, GO:0001503=GO_REF:0000033, GO:0045930=PMID:12408963, GO:0007420=GO_REF:0000033, GO:0048343=GO_REF:0000033, GO:0045893=PMID:11237714, GO:0008134=PMID:15684392, GO:0005634=GO_REF:0000052, GO:0051090=GO_REF:0000033, GO:0005737=GO_REF:0000052, GO:0001541=GO_REF:0000033, GO:0045944=GO_REF:0000024, GO:0042475=PMID:12614756, GO:0043010=GO_REF:0000033, GO:0005667=GO_REF:0000033, GO:0046620=GO_REF:0000033, GO:0048010=GO_REF:0000033, GO:0008354=GO_REF:0000033, GO:0043066=GO_REF:0000019, GO:0006355=PMID:15684392, GO:0035050=GO_REF:0000033, GO:0005730=GO_REF:0000052, GO:0003677=PMID:11179011, GO:0043565=PMID:7957066, GO:0032808=GO_REF:0000033, GO:0001974=GO_REF:0000033, GO:0001570=GO_REF:0000033} Q12948 Forkhead box protein C1 protein 20110119 {GO:0001656=IBA, GO:0005515=IPI, GO:0001657=IBA, GO:0003700=IDA, GO:0044212=ISS, GO:0055010=IBA, GO:0003705=IBA, GO:0001756=IBA, GO:0001654=IDA, GO:0048844=IBA, GO:0007507=IDA, GO:0001946=IBA, GO:0014034=IBA, GO:0003690=IBA, GO:0050880=IBA, GO:0007219=IBA, GO:0014032=IEA, GO:0030199=IBA, GO:0030203=IBA, GO:0008301=IDA, GO:0001701=IEA, GO:0031490=IBA, GO:0060038=IBA, GO:0001501=IEA, GO:0005720=IDA, GO:0001503=IBA, GO:0045930=IDA, GO:0007420=IBA, GO:0048343=IBA, GO:0045893=IDA, GO:0008134=IPI, GO:0005634=IDA, GO:0051090=IBA, GO:0005737=IDA, GO:0001541=IBA, GO:0045944=ISS, GO:0042475=IMP, GO:0043010=IBA, GO:0005667=IBA, GO:0046620=IBA, GO:0048010=IBA, GO:0008354=IBA, GO:0043066=IEA, GO:0006355=IDA, GO:0035050=IBA, GO:0005730=IDA, GO:0003677=IDA, GO:0043565=IDA, GO:0032808=IBA, GO:0001974=IBA, GO:0001570=IBA} Notch signaling pathway, artery morphogenesis, blood vessel remodeling, brain development, camera-type eye development, cardiac muscle cell proliferation, collagen fibril organization, embryonic heart tube development, eye development, germ cell migration, glycosaminoglycan metabolic process, heart development, in utero embryonic development, lacrimal gland development, lymphangiogenesis, metanephros development, negative regulation of apoptotic process, negative regulation of mitotic cell cycle, neural crest cell development, neural crest cell fate commitment, odontogenesis of dentin-containing tooth, ossification, ovarian follicle development, paraxial mesodermal cell fate commitment, positive regulation of transcription from RNA polymerase II promoter, positive regulation of transcription, DNA-dependent, regulation of blood vessel size, regulation of organ growth, regulation of sequence-specific DNA binding transcription factor activity, regulation of transcription, DNA-dependent, skeletal system development, somitogenesis, ureteric bud development, vascular endothelial growth factor receptor signaling pathway, vasculogenesis, ventricular cardiac muscle tissue morphogenesis cytoplasm, nuclear heterochromatin, nucleolus, nucleus, transcription factor complex DNA binding, DNA binding, bending, RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity, chromatin DNA binding, double-stranded DNA binding, protein binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, transcription factor binding, transcription regulatory region DNA binding Human UniProtKB:Q61572 FOXC2 BHF-UCL UniProtKB {GO:0001656=GO_REF:0000033, GO:0001657=GO_REF:0000033, GO:0003700=PMID:9169153, GO:0055010=GO_REF:0000033, GO:0044212=GO_REF:0000024, GO:0003705=GO_REF:0000033, GO:0001756=GO_REF:0000033, GO:0048844=GO_REF:0000033, GO:0048703=GO_REF:0000033, GO:0007507=PMID:21457232, GO:0001946=PMID:12114478, GO:0014034=GO_REF:0000033, GO:0003690=GO_REF:0000033, GO:0050880=GO_REF:0000033, GO:0014032=GO_REF:0000019, GO:0007219=GO_REF:0000033, GO:0030199=GO_REF:0000033, GO:0090050=GO_REF:0000024, GO:0008301=GO_REF:0000033, GO:0000122=GO_REF:0000024, GO:0060038=GO_REF:0000033, GO:0031490=PMID:16456100, GO:0010595=GO_REF:0000024, GO:0001503=GO_REF:0000033, GO:0035470=GO_REF:0000024, GO:0048343=GO_REF:0000033, GO:0045893=PMID:9169153, GO:0072144=GO_REF:0000019, GO:0008134=GO_REF:0000033, GO:0072011=GO_REF:0000019, GO:0008286=PMID:16456100, GO:0072112=GO_REF:0000019, GO:0005634=PMID:16081467, GO:0051090=GO_REF:0000033, GO:0045944=GO_REF:0000024, GO:0043010=GO_REF:0000033, GO:0009725=PMID:16456100, GO:0005667=GO_REF:0000033, GO:0048010=GO_REF:0000033, GO:0046620=GO_REF:0000033, GO:0043066=GO_REF:0000019, GO:0001569=GO_REF:0000033, GO:0035050=GO_REF:0000033, GO:0033630=GO_REF:0000024, GO:0043565=PMID:16081467, GO:0001077=PMID:20956529, GO:0001974=GO_REF:0000033, GO:0007498=PMID:8674414, GO:0001570=GO_REF:0000033} Q99958 Forkhead box protein C2 protein 20110119 {GO:0001656=IBA, GO:0001657=IBA, GO:0003700=IDA, GO:0055010=IBA, GO:0044212=ISS, GO:0003705=IBA, GO:0001756=IBA, GO:0048844=IBA, GO:0048703=IBA, GO:0007507=IMP, GO:0001946=IMP, GO:0014034=IBA, GO:0003690=IBA, GO:0050880=IBA, GO:0014032=IEA, GO:0007219=IBA, GO:0030199=IBA, GO:0090050=ISS, GO:0008301=IBA, GO:0000122=ISS, GO:0060038=IBA, GO:0031490=IDA, GO:0010595=ISS, GO:0001503=IBA, GO:0035470=ISS, GO:0048343=IBA, GO:0045893=IDA, GO:0072144=IEA, GO:0008134=IBA, GO:0072011=IEA, GO:0008286=IDA, GO:0072112=IEA, GO:0005634=IDA, GO:0051090=IBA, GO:0045944=ISS, GO:0043010=IBA, GO:0009725=IDA, GO:0005667=IBA, GO:0048010=IBA, GO:0046620=IBA, GO:0043066=IEA, GO:0001569=IBA, GO:0035050=IBA, GO:0033630=ISS, GO:0043565=IDA, GO:0001077=IDA, GO:0001974=IBA, GO:0007498=NAS, GO:0001570=IBA} Notch signaling pathway, artery morphogenesis, blood vessel remodeling, camera-type eye development, cardiac muscle cell proliferation, collagen fibril organization, embryonic heart tube development, embryonic viscerocranium morphogenesis, glomerular endothelium development, glomerular mesangial cell development, glomerular visceral epithelial cell differentiation, heart development, insulin receptor signaling pathway, lymphangiogenesis, mesoderm development, metanephros development, negative regulation of apoptotic process, negative regulation of transcription from RNA polymerase II promoter, neural crest cell development, neural crest cell fate commitment, ossification, paraxial mesodermal cell fate commitment, patterning of blood vessels, positive regulation of cell adhesion mediated by integrin, positive regulation of cell migration involved in sprouting angiogenesis, positive regulation of endothelial cell migration, positive regulation of transcription from RNA polymerase II promoter, positive regulation of transcription, DNA-dependent, positive regulation of vascular wound healing, regulation of blood vessel size, regulation of organ growth, regulation of sequence-specific DNA binding transcription factor activity, response to hormone stimulus, somitogenesis, ureteric bud development, vascular endothelial growth factor receptor signaling pathway, vasculogenesis, ventricular cardiac muscle tissue morphogenesis nucleus, transcription factor complex DNA binding, bending, RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription, RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity, chromatin DNA binding, double-stranded DNA binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, transcription factor binding, transcription regulatory region DNA binding Human UniProtKB:Q61850 FOXD3 BHF-UCL UniProtKB {GO:0005515=PMID:11891324, GO:0007389=GO_REF:0000033, GO:0000790=PMID:22306510, GO:0001658=GO_REF:0000033, GO:0003700=GO_REF:0000024, GO:0051216=GO_REF:0000033, GO:0003705=GO_REF:0000033, GO:0001755=GO_REF:0000033, GO:0048846=GO_REF:0000033, GO:0051090=GO_REF:0000033, GO:0003690=GO_REF:0000033, GO:0045944=PMID:11891324, GO:0005667=GO_REF:0000033, GO:0000977=PMID:22306510, GO:0008301=GO_REF:0000033, GO:0001822=GO_REF:0000033, GO:0001892=GO_REF:0000033, GO:0030318=GO_REF:0000033, GO:0000122=PMID:22306510, GO:0001829=GO_REF:0000033, GO:0001227=PMID:22306510, GO:0001701=GO_REF:0000024, GO:0048485=GO_REF:0000033, GO:0048484=GO_REF:0000033, GO:0007422=GO_REF:0000033, GO:0050935=GO_REF:0000033, GO:0048937=GO_REF:0000033, GO:0008134=GO_REF:0000033} Q9UJU5 Forkhead box protein D3 protein 20121109 {GO:0005515=IPI, GO:0007389=IBA, GO:0000790=IDA, GO:0001658=IBA, GO:0003700=ISS, GO:0051216=IBA, GO:0003705=IBA, GO:0001755=IBA, GO:0048846=IBA, GO:0051090=IBA, GO:0003690=IBA, GO:0045944=IDA, GO:0005667=IBA, GO:0000977=IDA, GO:0008301=IBA, GO:0001822=IBA, GO:0001892=IBA, GO:0030318=IBA, GO:0000122=IDA, GO:0001829=IBA, GO:0001227=IDA, GO:0001701=ISS, GO:0048485=IBA, GO:0048484=IBA, GO:0007422=IBA, GO:0050935=IBA, GO:0048937=IBA, GO:0008134=IBA} axon extension involved in axon guidance, branching involved in ureteric bud morphogenesis, cartilage development, embryonic placenta development, enteric nervous system development, in utero embryonic development, iridophore differentiation, kidney development, lateral line nerve glial cell development, melanocyte differentiation, negative regulation of transcription from RNA polymerase II promoter, neural crest cell migration, pattern specification process, peripheral nervous system development, positive regulation of transcription from RNA polymerase II promoter, regulation of sequence-specific DNA binding transcription factor activity, sympathetic nervous system development, trophectodermal cell differentiation nuclear chromatin, transcription factor complex DNA binding, bending, RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity, RNA polymerase II regulatory region sequence-specific DNA binding, RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription, double-stranded DNA binding, protein binding, sequence-specific DNA binding transcription factor activity, transcription factor binding Human FOXD4L6 HPA UniProtKB {GO:0005667=GO_REF:0000033, GO:0007389=GO_REF:0000033, GO:0090184=GO_REF:0000033, GO:0051216=GO_REF:0000033, GO:0008301=GO_REF:0000033, GO:0003705=GO_REF:0000033, GO:0001755=GO_REF:0000033, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0030318=GO_REF:0000033, GO:0009790=GO_REF:0000033, GO:0048846=GO_REF:0000033, GO:0048485=GO_REF:0000033, GO:0060678=GO_REF:0000033, GO:0048484=GO_REF:0000033, GO:0043565=GO_REF:0000002, GO:0051090=GO_REF:0000033, GO:0030513=GO_REF:0000033, GO:0003690=GO_REF:0000033, GO:0045944=GO_REF:0000033, GO:0050935=GO_REF:0000033, GO:0007422=GO_REF:0000033, GO:0048937=GO_REF:0000033, GO:0008134=GO_REF:0000033} Q3SYB3 Forkhead box protein D4-like 6 protein 20090616 {GO:0005667=IBA, GO:0007389=IBA, GO:0090184=IBA, GO:0051216=IBA, GO:0008301=IBA, GO:0003705=IBA, GO:0001755=IBA, GO:0005730=IDA, GO:0005634=IDA, GO:0030318=IBA, GO:0009790=IBA, GO:0048846=IBA, GO:0048485=IBA, GO:0060678=IBA, GO:0048484=IBA, GO:0043565=IEA, GO:0051090=IBA, GO:0030513=IBA, GO:0003690=IBA, GO:0045944=IBA, GO:0050935=IBA, GO:0007422=IBA, GO:0048937=IBA, GO:0008134=IBA} axon extension involved in axon guidance, cartilage development, dichotomous subdivision of terminal units involved in ureteric bud branching, embryo development, enteric nervous system development, iridophore differentiation, lateral line nerve glial cell development, melanocyte differentiation, neural crest cell migration, pattern specification process, peripheral nervous system development, positive regulation of BMP signaling pathway, positive regulation of kidney development, positive regulation of transcription from RNA polymerase II promoter, regulation of sequence-specific DNA binding transcription factor activity, sympathetic nervous system development nucleolus, nucleus, transcription factor complex DNA binding, bending, RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity, double-stranded DNA binding, sequence-specific DNA binding, transcription factor binding NOT Human FOXE1 UniProtKB UniProtKB {GO:0007389=GO_REF:0000033, GO:0003700=PMID:9697705, GO:0003705=GO_REF:0000033, GO:0048538=PMID:15494458, GO:0005634=PMID:9697705, GO:0030878=PMID:15494458, GO:0048846=GO_REF:0000033, GO:0009653=PMID:9169137, GO:0031069=GO_REF:0000024, GO:0051090=GO_REF:0000033, GO:0003690=GO_REF:0000033, GO:0002089=GO_REF:0000033, GO:0045944=GO_REF:0000033, GO:0006590=GO_REF:0000024, GO:0060022=PMID:12165566, GO:0060023=PMID:12165566, GO:0005667=GO_REF:0000033, GO:0008301=GO_REF:0000033, GO:0000122=GO_REF:0000024, GO:0003677=PMID:9697705, GO:0048485=GO_REF:0000033, GO:0048484=GO_REF:0000033, GO:0048562=GO_REF:0000024, GO:0043565=GO_REF:0000019, GO:0016477=GO_REF:0000024, GO:0060465=PMID:15494458, GO:0007422=GO_REF:0000033, GO:0048937=GO_REF:0000033, GO:0045893=PMID:9697705, GO:0045892=GO_REF:0000024, GO:0008134=GO_REF:0000033} O00358 Forkhead box protein E1 protein 20080611 {GO:0007389=IBA, GO:0003700=IDA, GO:0003705=IBA, GO:0048538=IEP, GO:0005634=IDA, GO:0030878=IEP, GO:0048846=IRD, GO:0009653=NAS, GO:0031069=ISS, GO:0051090=IBA, GO:0003690=IBA, GO:0002089=IBA, GO:0045944=IBA, GO:0006590=ISS, GO:0060022=IMP, GO:0060023=IMP, GO:0005667=IBA, GO:0008301=IBA, GO:0000122=ISS, GO:0003677=IDA, GO:0048485=IRD, GO:0048484=IRD, GO:0048562=ISS, GO:0043565=IEA, GO:0016477=ISS, GO:0060465=IEP, GO:0007422=IBA, GO:0048937=IRD, GO:0045893=IDA, GO:0045892=ISS, GO:0008134=IBA} anatomical structure morphogenesis, axon extension involved in axon guidance, cell migration, embryonic organ morphogenesis, enteric nervous system development, hair follicle morphogenesis, hard palate development, lateral line nerve glial cell development, lens morphogenesis in camera-type eye, negative regulation of transcription from RNA polymerase II promoter, negative regulation of transcription, DNA-dependent, pattern specification process, peripheral nervous system development, pharynx development, positive regulation of transcription from RNA polymerase II promoter, positive regulation of transcription, DNA-dependent, regulation of sequence-specific DNA binding transcription factor activity, soft palate development, sympathetic nervous system development, thymus development, thyroid gland development, thyroid hormone generation nucleus, transcription factor complex DNA binding, DNA binding, bending, RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity, double-stranded DNA binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, transcription factor binding Human UniProtKB:Q8R2I0 FOXF2 MGI UniProtKB {GO:0005667=PMID:9722567, GO:0007389=GO_REF:0000033, GO:0003700=PMID:9722567, GO:0008301=GO_REF:0000033, GO:0003705=GO_REF:0000033, GO:0005634=PMID:9722567, GO:0001837=PMID:19220249, GO:0048566=GO_REF:0000019, GO:0009790=GO_REF:0000033, GO:0003677=PMID:7957066, GO:0048596=GO_REF:0000019, GO:0042249=GO_REF:0000019, GO:0043565=PMID:7957066, GO:0051090=GO_REF:0000033, GO:0003690=GO_REF:0000033, GO:0030198=GO_REF:0000019, GO:0045944=PMID:8626802, GO:0009888=GO_REF:0000033, GO:0060021=PMID:19276632, GO:0048806=PMID:19276632, GO:0045893=PMID:8626802, GO:0045892=GO_REF:0000019, GO:0008134=PMID:9722567} Q12947 Forkhead box protein F2 protein 20100210 {GO:0005667=IDA, GO:0007389=IBA, GO:0003700=IDA, GO:0008301=IBA, GO:0003705=IBA, GO:0005634=IDA, GO:0001837=NAS, GO:0048566=IEA, GO:0009790=IBA, GO:0003677=IDA, GO:0048596=IEA, GO:0042249=IEA, GO:0043565=IDA, GO:0051090=IBA, GO:0003690=IBA, GO:0030198=IEA, GO:0045944=IDA, GO:0009888=IBA, GO:0060021=IMP, GO:0048806=IMP, GO:0045893=IDA, GO:0045892=IEA, GO:0008134=IPI} embryo development, embryonic camera-type eye morphogenesis, embryonic digestive tract development, epithelial to mesenchymal transition, establishment of planar polarity of embryonic epithelium, extracellular matrix organization, genitalia development, negative regulation of transcription, DNA-dependent, palate development, pattern specification process, positive regulation of transcription from RNA polymerase II promoter, positive regulation of transcription, DNA-dependent, regulation of sequence-specific DNA binding transcription factor activity, tissue development nucleus, transcription factor complex DNA binding, DNA binding, bending, RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity, double-stranded DNA binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, transcription factor binding Human FOXG1 PINC UniProtKB {GO:0005515=PMID:12657635, GO:0003705=GO_REF:0000033, GO:0005634=GO_REF:0000029, GO:0009953=GO_REF:0000033, GO:0009792=GO_REF:0000033, GO:0051090=GO_REF:0000033, GO:0003690=GO_REF:0000033, GO:0016199=GO_REF:0000033, GO:0045944=GO_REF:0000033, GO:0009888=GO_REF:0000033, GO:0005667=GO_REF:0000033, GO:0006355=GO_REF:0000029, GO:0042472=GO_REF:0000033, GO:0008301=GO_REF:0000033, GO:0007568=GO_REF:0000019, GO:0021954=GO_REF:0000033, GO:0002052=GO_REF:0000033, GO:0035058=GO_REF:0000033, GO:0003677=PMID:7959731, GO:0045787=GO_REF:0000033, GO:0043565=GO_REF:0000002, GO:0007346=GO_REF:0000033, GO:0045665=GO_REF:0000033, GO:0007420=PMID:7599184, GO:0030900=GO_REF:0000019, GO:0045892=PMID:12657635, GO:0030902=GO_REF:0000033, GO:0043584=GO_REF:0000033, GO:0008134=GO_REF:0000033} P55316 Forkhead box protein G1 protein 20030904 {GO:0005515=IPI, GO:0003705=IBA, GO:0005634=NAS, GO:0009953=IBA, GO:0009792=IBA, GO:0051090=IBA, GO:0003690=IBA, GO:0016199=IBA, GO:0045944=IBA, GO:0009888=IBA, GO:0005667=IBA, GO:0006355=NAS, GO:0042472=IBA, GO:0008301=IBA, GO:0007568=IEA, GO:0021954=IBA, GO:0002052=IBA, GO:0035058=IBA, GO:0003677=TAS, GO:0045787=IBA, GO:0043565=IEA, GO:0007346=IBA, GO:0045665=IBA, GO:0007420=TAS, GO:0030900=IEA, GO:0045892=IDA, GO:0030902=IBA, GO:0043584=IBA, GO:0008134=IBA} aging, axon midline choice point recognition, brain development, central nervous system neuron development, dorsal/ventral pattern formation, embryo development ending in birth or egg hatching, forebrain development, hindbrain development, inner ear morphogenesis, negative regulation of neuron differentiation, negative regulation of transcription, DNA-dependent, nonmotile primary cilium assembly, nose development, positive regulation of cell cycle, positive regulation of neuroblast proliferation, positive regulation of transcription from RNA polymerase II promoter, regulation of mitotic cell cycle, regulation of sequence-specific DNA binding transcription factor activity, regulation of transcription, DNA-dependent, tissue development nucleus, transcription factor complex DNA binding, DNA binding, bending, RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity, double-stranded DNA binding, protein binding, sequence-specific DNA binding, transcription factor binding Human FOXH1 BHF-UCL UniProtKB {GO:0005515=PMID:17474147, GO:0003700=PMID:17438144, GO:0001190=GO_REF:0000019, GO:0044212=GO_REF:0000024, GO:0003705=GO_REF:0000033, GO:0003139=GO_REF:0000019, GO:0005634=PMID:16120611, GO:0003215=GO_REF:0000019, GO:0050681=PMID:16120611, GO:0001947=GO_REF:0000033, GO:0051090=GO_REF:0000033, GO:0042074=GO_REF:0000033, GO:0003690=GO_REF:0000033, GO:0003146=GO_REF:0000033, GO:0045944=PMID:9702198, GO:1900164=PMID:17507406, GO:0003222=GO_REF:0000019, GO:0007179=GO_REF:0000024, GO:0010159=GO_REF:0000033, GO:0005667=PMID:17438144, GO:0048318=GO_REF:0000033, GO:0001568=GO_REF:0000033, GO:0001104=GO_REF:0000019, GO:0008301=GO_REF:0000033, GO:0019904=PMID:9702198, GO:0070410=PMID:16120611, GO:0035909=GO_REF:0000019, GO:0035054=GO_REF:0000033, GO:0060766=PMID:16120611, GO:0021508=GO_REF:0000033, GO:0070412=PMID:16120611, GO:2000824=PMID:16120611, GO:0003677=PMID:9389648, GO:0003151=GO_REF:0000019, GO:0032444=PMID:9389648, GO:0043565=PMID:9702198, GO:0005654=Reactome:REACT_111132, GO:0033147=PMID:16120611, GO:0045893=PMID:9389648, GO:0008134=GO_REF:0000033} O75593 Forkhead box protein H1 protein 20120516 {GO:0005515=IPI, GO:0003700=IDA, GO:0001190=IEA, GO:0044212=ISS, GO:0003705=IBA, GO:0003139=IEA, GO:0005634=IDA, GO:0003215=IEA, GO:0050681=IPI, GO:0001947=IBA, GO:0051090=IBA, GO:0042074=IBA, GO:0003690=IBA, GO:0003146=IRD, GO:0045944=IDA, GO:1900164=NAS, GO:0003222=IEA, GO:0007179=ISS, GO:0010159=IBA, GO:0005667=IDA, GO:0048318=IBA, GO:0001568=IBA, GO:0001104=IEA, GO:0008301=IBA, GO:0019904=IPI, GO:0070410=IMP, GO:0035909=IEA, GO:0035054=IBA, GO:0060766=IDA, GO:0021508=IBA, GO:0070412=IMP, GO:2000824=IDA, GO:0003677=IDA, GO:0003151=IEA, GO:0032444=IDA, GO:0043565=IDA, GO:0005654=TAS, GO:0033147=IDA, GO:0045893=IDA, GO:0008134=IBA} aorta morphogenesis, axial mesoderm development, blood vessel development, cardiac right ventricle morphogenesis, cell migration involved in gastrulation, embryonic heart tube anterior/posterior pattern specification, floor plate formation, heart jogging, heart looping, negative regulation of androgen receptor activity, negative regulation of androgen receptor signaling pathway, negative regulation of intracellular estrogen receptor signaling pathway, nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry, outflow tract morphogenesis, positive regulation of transcription from RNA polymerase II promoter, positive regulation of transcription, DNA-dependent, regulation of sequence-specific DNA binding transcription factor activity, secondary heart field specification, specification of organ position, transforming growth factor beta receptor signaling pathway, ventricular trabecula myocardium morphogenesis activin responsive factor complex, nucleoplasm, nucleus, transcription factor complex DNA binding, DNA binding, bending, R-SMAD binding, RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity, RNA polymerase II transcription cofactor activity, RNA polymerase II transcription factor binding transcription factor activity involved in positive regulation of transcription, androgen receptor binding, co-SMAD binding, double-stranded DNA binding, protein binding, protein domain specific binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, transcription factor binding, transcription regulatory region DNA binding Human UniProtKB:P10275 FOXI1 UniProtKB UniProtKB {GO:0005667=GO_REF:0000033, GO:0007389=GO_REF:0000033, GO:0003700=PMID:19214237, GO:0044212=GO_REF:0000024, GO:0008301=GO_REF:0000033, GO:0003705=GO_REF:0000033, GO:0005634=PMID:19214237, GO:0009790=PMID:7957066, GO:0043565=GO_REF:0000024, GO:0051090=GO_REF:0000033, GO:0003690=GO_REF:0000033, GO:0009957=GO_REF:0000033, GO:0045944=PMID:19214237, GO:0043049=GO_REF:0000033, GO:0008134=GO_REF:0000033} Q12951 Forkhead box protein I1 protein 20100415 {GO:0005667=IBA, GO:0007389=IBA, GO:0003700=IDA, GO:0044212=ISS, GO:0008301=IBA, GO:0003705=IBA, GO:0005634=IC, GO:0009790=NAS, GO:0043565=ISS, GO:0051090=IBA, GO:0003690=IBA, GO:0009957=IBA, GO:0045944=IDA, GO:0043049=IBA, GO:0008134=IBA} embryo development, epidermal cell fate specification, otic placode formation, pattern specification process, positive regulation of transcription from RNA polymerase II promoter, regulation of sequence-specific DNA binding transcription factor activity nucleus, transcription factor complex DNA binding, bending, RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity, double-stranded DNA binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, transcription factor binding, transcription regulatory region DNA binding Human UniProtKB:Q922I5 FOXJ1 BHF-UCL UniProtKB {GO:0007389=GO_REF:0000024, GO:1901248=PMID:20539013, GO:0060428=PMID:9530170, GO:0030036=GO_REF:0000024, GO:0003700=PMID:9073514, GO:0030324=GO_REF:0000033, GO:0033085=GO_REF:0000024, GO:0003705=GO_REF:0000033, GO:0035089=GO_REF:0000024, GO:0045409=GO_REF:0000024, GO:0005634=PMID:17008636, GO:0072016=PMID:9530170, GO:0007283=PMID:9073514, GO:0050900=GO_REF:0000024, GO:0042130=GO_REF:0000033, GO:0001947=GO_REF:0000033, GO:0003690=GO_REF:0000033, GO:0060972=GO_REF:0000033, GO:0045944=PMID:9096351, GO:0006959=GO_REF:0000024, GO:0030855=GO_REF:0000033, GO:0002635=GO_REF:0000024, GO:0002924=GO_REF:0000024, GO:0005667=GO_REF:0000033, GO:0000976=PMID:9096351, GO:0008301=GO_REF:0000033, GO:0050869=GO_REF:0000024, GO:0019904=GO_REF:0000033, GO:0035502=PMID:9530170, GO:0002508=GO_REF:0000024, GO:0032088=GO_REF:0000024, GO:0000122=GO_REF:0000024, GO:0032862=GO_REF:0000024, GO:0002897=GO_REF:0000024, GO:0003677=PMID:9073514, GO:0042384=GO_REF:0000024, GO:0007420=PMID:9096351, GO:0008134=GO_REF:0000033} Q92949 Forkhead box protein J1 protein 20120808 {GO:0007389=ISS, GO:1901248=IDA, GO:0060428=IEP, GO:0030036=ISS, GO:0003700=NAS, GO:0030324=IBA, GO:0033085=ISS, GO:0003705=IBA, GO:0035089=ISS, GO:0045409=ISS, GO:0005634=IDA, GO:0072016=IEP, GO:0007283=NAS, GO:0050900=ISS, GO:0042130=IBA, GO:0001947=IBA, GO:0003690=IBA, GO:0060972=IBA, GO:0045944=IDA, GO:0006959=ISS, GO:0030855=IBA, GO:0002635=ISS, GO:0002924=ISS, GO:0005667=IBA, GO:0000976=IDA, GO:0008301=IBA, GO:0050869=ISS, GO:0019904=IBA, GO:0035502=IEP, GO:0002508=ISS, GO:0032088=ISS, GO:0000122=ISS, GO:0032862=ISS, GO:0002897=ISS, GO:0003677=NAS, GO:0042384=ISS, GO:0007420=NAS, GO:0008134=IBA} actin cytoskeleton organization, activation of Rho GTPase activity, brain development, central tolerance induction, cilium assembly, epithelial cell differentiation, establishment of apical/basal cell polarity, glomerular parietal epithelial cell development, heart looping, humoral immune response, left/right pattern formation, leukocyte migration, lung development, lung epithelium development, metanephric part of ureteric bud development, negative regulation of B cell activation, negative regulation of NF-kappaB transcription factor activity, negative regulation of T cell differentiation in thymus, negative regulation of T cell proliferation, negative regulation of germinal center formation, negative regulation of humoral immune response mediated by circulating immunoglobulin, negative regulation of interleukin-6 biosynthetic process, negative regulation of transcription from RNA polymerase II promoter, pattern specification process, positive regulation of central B cell tolerance induction, positive regulation of lung ciliated cell differentiation, positive regulation of transcription from RNA polymerase II promoter, spermatogenesis nucleus, transcription factor complex DNA binding, DNA binding, bending, RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity, double-stranded DNA binding, protein domain specific binding, sequence-specific DNA binding transcription factor activity, transcription factor binding, transcription regulatory region sequence-specific DNA binding Human FOXJ2 HPA UniProtKB {GO:0005667=GO_REF:0000033, GO:0007389=GO_REF:0000033, GO:0008301=GO_REF:0000033, GO:0003705=GO_REF:0000033, GO:0019904=GO_REF:0000033, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0009790=GO_REF:0000033, GO:0048513=GO_REF:0000033, GO:0043565=GO_REF:0000002, GO:0051090=GO_REF:0000033, GO:0003690=GO_REF:0000033, GO:0009888=GO_REF:0000033, GO:0008134=GO_REF:0000033} Q9P0K8 Forkhead box protein J2 protein 20101115 {GO:0005667=IBA, GO:0007389=IBA, GO:0008301=IBA, GO:0003705=IBA, GO:0019904=IBA, GO:0005730=IDA, GO:0005634=IDA, GO:0009790=IBA, GO:0048513=IBA, GO:0043565=IEA, GO:0051090=IBA, GO:0003690=IBA, GO:0009888=IBA, GO:0008134=IBA} embryo development, organ development, pattern specification process, regulation of sequence-specific DNA binding transcription factor activity, tissue development nucleolus, nucleus, transcription factor complex DNA binding, bending, RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity, double-stranded DNA binding, protein domain specific binding, sequence-specific DNA binding, transcription factor binding Human FOXJ3 RefGenome UniProtKB {GO:0005667=GO_REF:0000033, GO:0007389=GO_REF:0000033, GO:0003700=GO_REF:0000002, GO:0008301=GO_REF:0000033, GO:0003705=GO_REF:0000033, GO:0019904=GO_REF:0000033, GO:0005634=GO_REF:0000038, GO:0048513=GO_REF:0000033, GO:0009790=GO_REF:0000033, GO:0006351=GO_REF:0000038, GO:0043565=GO_REF:0000002, GO:0051090=GO_REF:0000033, GO:0003690=GO_REF:0000033, GO:0009888=GO_REF:0000033, GO:0045893=GO_REF:0000033, GO:0008134=GO_REF:0000033} Q9UPW0 Forkhead box protein J3 protein 20100514 {GO:0005667=IBA, GO:0007389=IBA, GO:0003700=IEA, GO:0008301=IBA, GO:0003705=IBA, GO:0019904=IBA, GO:0005634=IEA, GO:0048513=IBA, GO:0009790=IBA, GO:0006351=IEA, GO:0043565=IEA, GO:0051090=IBA, GO:0003690=IBA, GO:0009888=IBA, GO:0045893=IBA, GO:0008134=IBA} embryo development, organ development, pattern specification process, positive regulation of transcription, DNA-dependent, regulation of sequence-specific DNA binding transcription factor activity, tissue development, transcription, DNA-dependent nucleus, transcription factor complex DNA binding, bending, RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity, double-stranded DNA binding, protein domain specific binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, transcription factor binding Human PANTHER:PTN000215024 FOXK1 HPA UniProtKB {GO:0005515=PMID:21903422, GO:0005667=GO_REF:0000033, GO:0007389=GO_REF:0000033, GO:0030308=GO_REF:0000019, GO:0000287=GO_REF:0000033, GO:0008301=GO_REF:0000033, GO:0003705=GO_REF:0000033, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0009790=GO_REF:0000033, GO:0030154=GO_REF:0000037, GO:0043565=GO_REF:0000019, GO:0051090=GO_REF:0000033, GO:0007517=GO_REF:0000037, GO:0003690=GO_REF:0000033, GO:0009888=GO_REF:0000033, GO:0045893=GO_REF:0000019, GO:0045892=GO_REF:0000019, GO:0008134=GO_REF:0000033} P85037 Forkhead box protein K1 protein 20101115 {GO:0005515=IPI, GO:0005667=IBA, GO:0007389=IBA, GO:0030308=IEA, GO:0000287=IBA, GO:0008301=IBA, GO:0003705=IBA, GO:0005730=IDA, GO:0005634=IDA, GO:0009790=IBA, GO:0030154=IEA, GO:0043565=IEA, GO:0051090=IBA, GO:0007517=IEA, GO:0003690=IBA, GO:0009888=IBA, GO:0045893=IEA, GO:0045892=IEA, GO:0008134=IBA} cell differentiation, embryo development, muscle organ development, negative regulation of cell growth, negative regulation of transcription, DNA-dependent, pattern specification process, positive regulation of transcription, DNA-dependent, regulation of sequence-specific DNA binding transcription factor activity, tissue development nucleolus, nucleus, transcription factor complex DNA binding, bending, RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity, double-stranded DNA binding, magnesium ion binding, protein binding, sequence-specific DNA binding, transcription factor binding NOT Human FOXK2 HPA UniProtKB {GO:0005515=PMID:21903422, GO:0005667=GO_REF:0000033, GO:0007389=GO_REF:0000033, GO:0006355=PMID:12402362, GO:0000287=PMID:16624804, GO:0003700=PMID:12402362, GO:0006357=PMID:1909027, GO:0008301=GO_REF:0000033, GO:0003705=GO_REF:0000033, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0009790=GO_REF:0000033, GO:0006351=GO_REF:0000038, GO:0043231=GO_REF:0000052, GO:0043565=PMID:12402362, GO:0051090=GO_REF:0000033, GO:0003690=GO_REF:0000033, GO:0009888=GO_REF:0000033, GO:0008134=GO_REF:0000033} Q01167 Forkhead box protein K2 protein 20100326 {GO:0005515=IPI, GO:0005667=IBA, GO:0007389=IBA, GO:0006355=NAS, GO:0000287=IDA, GO:0003700=NAS, GO:0006357=TAS, GO:0008301=IBA, GO:0003705=IBA, GO:0005730=IDA, GO:0005634=IDA, GO:0009790=IBA, GO:0006351=IEA, GO:0043231=IDA, GO:0043565=IDA, GO:0051090=IBA, GO:0003690=IBA, GO:0009888=IBA, GO:0008134=IBA} embryo development, pattern specification process, regulation of sequence-specific DNA binding transcription factor activity, regulation of transcription from RNA polymerase II promoter, regulation of transcription, DNA-dependent, tissue development, transcription, DNA-dependent intracellular membrane-bounded organelle, nucleolus, nucleus, transcription factor complex DNA binding, bending, RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity, double-stranded DNA binding, magnesium ion binding, protein binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, transcription factor binding Human FOXL1 MGI UniProtKB {GO:0035136=GO_REF:0000033, GO:0005667=GO_REF:0000033, GO:0007389=GO_REF:0000033, GO:0006355=GO_REF:0000029, GO:0003700=GO_REF:0000024, GO:0030111=GO_REF:0000024, GO:0051216=GO_REF:0000033, GO:0008301=GO_REF:0000033, GO:0003705=GO_REF:0000033, GO:0005634=PMID:7957066, GO:0007275=PMID:11078474, GO:0009790=GO_REF:0000033, GO:0003677=PMID:7957066, GO:0030166=GO_REF:0000024, GO:0043565=PMID:7957066, GO:0007507=PMID:21457232, GO:0051090=GO_REF:0000033, GO:0003690=GO_REF:0000033, GO:0007420=GO_REF:0000033, GO:0007495=GO_REF:0000024, GO:0009887=GO_REF:0000024, GO:0043010=GO_REF:0000033, GO:0008134=GO_REF:0000033} Q12952 Forkhead box protein L1 protein 20061227 {GO:0035136=IBA, GO:0005667=IBA, GO:0007389=IBA, GO:0006355=NAS, GO:0003700=ISS, GO:0030111=ISS, GO:0051216=IBA, GO:0008301=IBA, GO:0003705=IBA, GO:0005634=IC, GO:0007275=NAS, GO:0009790=IBA, GO:0003677=IDA, GO:0030166=ISS, GO:0043565=IDA, GO:0007507=IMP, GO:0051090=IBA, GO:0003690=IBA, GO:0007420=IBA, GO:0007495=ISS, GO:0009887=ISS, GO:0043010=IBA, GO:0008134=IBA} brain development, camera-type eye development, cartilage development, embryo development, forelimb morphogenesis, heart development, multicellular organismal development, organ morphogenesis, pattern specification process, proteoglycan biosynthetic process, regulation of Wnt receptor signaling pathway, regulation of sequence-specific DNA binding transcription factor activity, regulation of transcription, DNA-dependent, visceral mesoderm-endoderm interaction involved in midgut development nucleus, transcription factor complex DNA binding, DNA binding, bending, RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity, double-stranded DNA binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, transcription factor binding Human FOXL2 UniProtKB UniProtKB {GO:0005515=PMID:16153597, GO:0007389=GO_REF:0000033, GO:0003700=PMID:12471206, GO:0003705=GO_REF:0000033, GO:0042703=PMID:12161610, GO:0005634=PMID:12471206, GO:0030154=PMID:12471206, GO:0051090=GO_REF:0000033, GO:0060026=GO_REF:0000033, GO:0001541=GO_REF:0000024, GO:0003690=GO_REF:0000033, GO:0045944=GO_REF:0000033, GO:0031624=PMID:19744555, GO:0048048=GO_REF:0000033, GO:0043028=PMID:16153597, GO:0005667=GO_REF:0000033, GO:0043065=PMID:16153597, GO:0008301=GO_REF:0000033, GO:0030331=GO_REF:0000033, GO:0006917=GO_REF:0000033, GO:0003677=PMID:11175783, GO:0043280=PMID:16153597, GO:0043565=GO_REF:0000002, GO:0019101=GO_REF:0000033, GO:0006309=PMID:16153597, GO:0002074=PMID:12630957, GO:0045893=GO_REF:0000024, GO:0045892=PMID:19744555, GO:0060014=GO_REF:0000019, GO:0008134=GO_REF:0000033} P58012 Forkhead box protein L2 protein 20091221 {GO:0005515=IPI, GO:0007389=IBA, GO:0003700=NAS, GO:0003705=IBA, GO:0042703=IMP, GO:0005634=IDA, GO:0030154=NAS, GO:0051090=IBA, GO:0060026=IBA, GO:0001541=ISS, GO:0003690=IBA, GO:0045944=IBA, GO:0031624=IPI, GO:0048048=IBA, GO:0043028=IMP, GO:0005667=IBA, GO:0043065=IMP, GO:0008301=IBA, GO:0030331=IBA, GO:0006917=IBA, GO:0003677=TAS, GO:0043280=IMP, GO:0043565=IEA, GO:0019101=IBA, GO:0006309=IMP, GO:0002074=IMP, GO:0045893=ISS, GO:0045892=IDA, GO:0060014=IEA, GO:0008134=IBA} apoptotic DNA fragmentation, cell differentiation, convergent extension, embryonic eye morphogenesis, extraocular skeletal muscle development, female somatic sex determination, granulosa cell differentiation, induction of apoptosis, menstruation, negative regulation of transcription, DNA-dependent, ovarian follicle development, pattern specification process, positive regulation of apoptotic process, positive regulation of cysteine-type endopeptidase activity involved in apoptotic process, positive regulation of transcription from RNA polymerase II promoter, positive regulation of transcription, DNA-dependent, regulation of sequence-specific DNA binding transcription factor activity nucleus, transcription factor complex DNA binding, DNA binding, bending, RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity, cysteine-type endopeptidase regulator activity involved in apoptotic process, double-stranded DNA binding, estrogen receptor binding, protein binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, transcription factor binding, ubiquitin conjugating enzyme binding Human UniProtKB:P63279 FOXM1 BHF-UCL UniProtKB {GO:0071156=PMID:19696738, GO:0005515=PMID:16809346, GO:0007389=GO_REF:0000033, GO:0008284=PMID:19696738, GO:0003700=GO_REF:0000002, GO:0044212=GO_REF:0000019, GO:0003705=GO_REF:0000033, GO:0090344=PMID:19696738, GO:0005634=GO_REF:0000052, GO:0046578=PMID:19696738, GO:0009790=GO_REF:0000033, GO:0032873=PMID:19696738, GO:0051090=GO_REF:0000033, GO:0005737=GO_REF:0000052, GO:0003690=GO_REF:0000033, GO:0045944=PMID:20531406, GO:0000086=PMID:19160488, GO:0009888=GO_REF:0000033, GO:0006978=PMID:17101782, GO:0005667=GO_REF:0000033, GO:0019901=PMID:19160488, GO:0008301=GO_REF:0000033, GO:0019904=GO_REF:0000033, GO:0005730=GO_REF:0000052, GO:0000122=PMID:20531406, GO:0001889=GO_REF:0000033, GO:0043565=GO_REF:0000002, GO:0006281=GO_REF:0000037, GO:2000377=PMID:19696738, GO:2000781=PMID:17101782, GO:0045893=PMID:20531406, GO:0001570=GO_REF:0000033, GO:0045892=PMID:20531406, GO:0008134=GO_REF:0000033} Q08050 Forkhead box protein M1 protein 20110418 {GO:0071156=IMP, GO:0005515=IPI, GO:0007389=IBA, GO:0008284=IMP, GO:0003700=IEA, GO:0044212=IEA, GO:0003705=IBA, GO:0090344=IMP, GO:0005634=IDA, GO:0046578=IMP, GO:0009790=IBA, GO:0032873=IMP, GO:0051090=IBA, GO:0005737=IDA, GO:0003690=IBA, GO:0045944=IMP, GO:0000086=IDA, GO:0009888=IBA, GO:0006978=IMP, GO:0005667=IBA, GO:0019901=IPI, GO:0008301=IBA, GO:0019904=IBA, GO:0005730=IDA, GO:0000122=IMP, GO:0001889=IBA, GO:0043565=IEA, GO:0006281=IEA, GO:2000377=IMP, GO:2000781=IMP, GO:0045893=IMP, GO:0001570=IBA, GO:0045892=IMP, GO:0008134=IBA} DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, DNA repair, G2/M transition of mitotic cell cycle, embryo development, liver development, negative regulation of cell aging, negative regulation of stress-activated MAPK cascade, negative regulation of transcription from RNA polymerase II promoter, negative regulation of transcription, DNA-dependent, pattern specification process, positive regulation of cell proliferation, positive regulation of double-strand break repair, positive regulation of transcription from RNA polymerase II promoter, positive regulation of transcription, DNA-dependent, regulation of Ras protein signal transduction, regulation of cell cycle arrest, regulation of reactive oxygen species metabolic process, regulation of sequence-specific DNA binding transcription factor activity, tissue development, vasculogenesis cytoplasm, nucleolus, nucleus, transcription factor complex DNA binding, bending, RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity, double-stranded DNA binding, protein binding, protein domain specific binding, protein kinase binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, transcription factor binding, transcription regulatory region DNA binding Human FOXN2 HPA UniProtKB {GO:0005667=GO_REF:0000033, GO:0007389=GO_REF:0000033, GO:0003700=PMID:1639393, GO:0008301=GO_REF:0000033, GO:0003705=GO_REF:0000033, GO:0005634=GO_REF:0000052, GO:0009790=GO_REF:0000033, GO:0006351=GO_REF:0000038, GO:0043231=GO_REF:0000052, GO:0043565=GO_REF:0000002, GO:0051090=GO_REF:0000033, GO:0003690=GO_REF:0000033, GO:0009888=GO_REF:0000033, GO:0008134=GO_REF:0000033} P32314 Forkhead box protein N2 protein 20101115 {GO:0005667=IBA, GO:0007389=IBA, GO:0003700=TAS, GO:0008301=IBA, GO:0003705=IBA, GO:0005634=IDA, GO:0009790=IBA, GO:0006351=IEA, GO:0043231=IDA, GO:0043565=IEA, GO:0051090=IBA, GO:0003690=IBA, GO:0009888=IBA, GO:0008134=IBA} embryo development, pattern specification process, regulation of sequence-specific DNA binding transcription factor activity, tissue development, transcription, DNA-dependent intracellular membrane-bounded organelle, nucleus, transcription factor complex DNA binding, bending, RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity, double-stranded DNA binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, transcription factor binding Human FOXN3 IntAct UniProtKB {GO:0005515=PMID:16102918, GO:0005667=GO_REF:0000033, GO:0007389=GO_REF:0000033, GO:0003700=GO_REF:0000002, GO:0008301=GO_REF:0000033, GO:0003705=GO_REF:0000033, GO:0005634=PMID:16102918, GO:0009790=GO_REF:0000033, GO:0008022=PMID:16951149, GO:0006351=GO_REF:0000038, GO:0043565=GO_REF:0000002, GO:0000085=PMID:9154802, GO:0051090=GO_REF:0000033, GO:0003690=GO_REF:0000033, GO:0009888=GO_REF:0000033, GO:0000077=PMID:9154802, GO:0045892=PMID:16102918, GO:0008134=GO_REF:0000033} O00409 Forkhead box protein N3 protein 20130415 {GO:0005515=IPI, GO:0005667=IBA, GO:0007389=IBA, GO:0003700=IEA, GO:0008301=IBA, GO:0003705=IBA, GO:0005634=IC, GO:0009790=IBA, GO:0008022=IPI, GO:0006351=IEA, GO:0043565=IEA, GO:0000085=TAS, GO:0051090=IBA, GO:0003690=IBA, GO:0009888=IBA, GO:0000077=TAS, GO:0045892=IDA, GO:0008134=IBA} DNA damage checkpoint, G2 phase of mitotic cell cycle, embryo development, negative regulation of transcription, DNA-dependent, pattern specification process, regulation of sequence-specific DNA binding transcription factor activity, tissue development, transcription, DNA-dependent nucleus, transcription factor complex DNA binding, bending, RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity, double-stranded DNA binding, protein C-terminus binding, protein binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, transcription factor binding Human UniProtKB:Q13573 FOXO1 BHF-UCL UniProtKB {GO:0005515=PMID:18408765, GO:0008286=GO_REF:0000024, GO:0007389=GO_REF:0000033, GO:0001659=PMID:22510882, GO:0001678=PMID:22510882, GO:0071732=GO_REF:0000024, GO:0045599=GO_REF:0000024, GO:0003705=GO_REF:0000033, GO:0005634=GO_REF:0000052, GO:0009790=GO_REF:0000033, GO:0048513=GO_REF:0000033, GO:0032873=PMID:19696738, GO:0005829=Reactome:REACT_13699, GO:0005739=PMID:22510882, GO:0051090=GO_REF:0000033, GO:0005737=PMID:11237865, GO:0003690=GO_REF:0000033, GO:0007173=Reactome:REACT_9417, GO:0045944=PMID:12228231, GO:0042127=GO_REF:0000033, GO:0009888=GO_REF:0000033, GO:0045444=PMID:22510882, GO:0051721=GO_REF:0000024, GO:0006473=PMID:22510882, GO:0009267=PMID:22510882, GO:0005667=GO_REF:0000033, GO:0048011=Reactome:REACT_11061, GO:0043066=PMID:10871843, GO:0001568=GO_REF:0000033, GO:0019901=GO_REF:0000033, GO:0008301=GO_REF:0000033, GO:0048015=Reactome:REACT_12464, GO:0045722=GO_REF:0000019, GO:0006915=GO_REF:0000037, GO:0006974=GO_REF:0000024, GO:0070417=PMID:22510882, GO:0043565=PMID:12228231, GO:0001078=GO_REF:0000019, GO:0008543=Reactome:REACT_9470, GO:0045087=Reactome:REACT_6802, GO:0031018=Reactome:REACT_13819, GO:0003682=PMID:22510882, GO:0005654=Reactome:REACT_147827, GO:0034599=GO_REF:0000024, GO:0045893=PMID:12228231, GO:2000505=PMID:22510882, GO:0045892=PMID:22510882, GO:0008134=GO_REF:0000033} Q12778 Forkhead box protein O1 protein 20100202 {GO:0005515=IPI, GO:0008286=ISS, GO:0007389=IBA, GO:0001659=ISS, GO:0001678=ISS, GO:0071732=ISS, GO:0045599=ISS, GO:0003705=IBA, GO:0005634=IDA, GO:0009790=IBA, GO:0048513=IBA, GO:0032873=IDA, GO:0005829=TAS, GO:0005739=ISS, GO:0051090=IBA, GO:0005737=IDA, GO:0003690=IBA, GO:0007173=TAS, GO:0045944=IDA, GO:0042127=IBA, GO:0009888=IBA, GO:0045444=ISS, GO:0051721=ISS, GO:0006473=ISS, GO:0009267=ISS, GO:0005667=IBA, GO:0048011=TAS, GO:0043066=IDA, GO:0001568=IBA, GO:0019901=IBA, GO:0008301=IBA, GO:0048015=TAS, GO:0045722=IEA, GO:0006915=IEA, GO:0006974=ISS, GO:0070417=ISS, GO:0043565=IDA, GO:0001078=IEA, GO:0008543=TAS, GO:0045087=TAS, GO:0031018=TAS, GO:0003682=ISS, GO:0005654=TAS, GO:0034599=ISS, GO:0045893=IDA, GO:2000505=ISS, GO:0045892=ISS, GO:0008134=IBA} apoptotic process, blood vessel development, cellular glucose homeostasis, cellular response to cold, cellular response to nitric oxide, cellular response to oxidative stress, cellular response to starvation, embryo development, endocrine pancreas development, epidermal growth factor receptor signaling pathway, fat cell differentiation, fibroblast growth factor receptor signaling pathway, innate immune response, insulin receptor signaling pathway, negative regulation of apoptotic process, negative regulation of fat cell differentiation, negative regulation of stress-activated MAPK cascade, negative regulation of transcription, DNA-dependent, neurotrophin TRK receptor signaling pathway, organ development, pattern specification process, phosphatidylinositol-mediated signaling, positive regulation of gluconeogenesis, positive regulation of transcription from RNA polymerase II promoter, positive regulation of transcription, DNA-dependent, protein acetylation, regulation of cell proliferation, regulation of energy homeostasis, regulation of sequence-specific DNA binding transcription factor activity, response to DNA damage stimulus, temperature homeostasis, tissue development cytoplasm, cytosol, mitochondrion, nucleoplasm, nucleus, transcription factor complex DNA binding, bending, RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription, RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity, chromatin binding, double-stranded DNA binding, protein binding, protein kinase binding, protein phosphatase 2A binding, sequence-specific DNA binding, transcription factor binding Human FOXO3 BHF-UCL UniProtKB {GO:0005515=PMID:21909281, GO:0008286=GO_REF:0000033, GO:0007389=GO_REF:0000033, GO:0003700=PMID:14734530, GO:0003705=GO_REF:0000033, GO:0005634=PMID:22761832, GO:0001556=GO_REF:0000033, GO:0009790=GO_REF:0000033, GO:0005829=GO_REF:0000033, GO:0051090=GO_REF:0000033, GO:0005737=PMID:21329882, GO:0003690=GO_REF:0000033, GO:0007173=Reactome:REACT_9417, GO:0045944=PMID:14734530, GO:0042127=GO_REF:0000033, GO:0009888=GO_REF:0000033, GO:0005667=GO_REF:0000033, GO:0048011=Reactome:REACT_11061, GO:0019901=PMID:21329882, GO:0030330=GO_REF:0000019, GO:0008301=GO_REF:0000033, GO:0048015=Reactome:REACT_12464, GO:0006950=PMID:21329882, GO:0001544=GO_REF:0000033, GO:0006915=PMID:10102273, GO:0001542=GO_REF:0000033, GO:0000122=PMID:18787191, GO:0042593=GO_REF:0000033, GO:0006917=GO_REF:0000033, GO:0003677=PMID:21329882, GO:0006417=PMID:21329882, GO:0006974=GO_REF:0000033, GO:0001547=GO_REF:0000033, GO:0043565=PMID:10102273, GO:0016020=GO_REF:0000019, GO:0008543=Reactome:REACT_9470, GO:0045648=PMID:14734530, GO:0045087=Reactome:REACT_6802, GO:0005654=Reactome:REACT_147827, GO:0045893=PMID:10102273, GO:0008134=GO_REF:0000033} O43524 Forkhead box protein O3 protein 20100520 {GO:0005515=IPI, GO:0008286=IBA, GO:0007389=IBA, GO:0003700=IDA, GO:0003705=IBA, GO:0005634=IDA, GO:0001556=IBA, GO:0009790=IBA, GO:0005829=IBA, GO:0051090=IBA, GO:0005737=IDA, GO:0003690=IBA, GO:0007173=TAS, GO:0045944=IDA, GO:0042127=IBA, GO:0009888=IBA, GO:0005667=IBA, GO:0048011=TAS, GO:0019901=IPI, GO:0030330=IEA, GO:0008301=IBA, GO:0048015=TAS, GO:0006950=IDA, GO:0001544=IBA, GO:0006915=IDA, GO:0001542=IBA, GO:0000122=IMP, GO:0042593=IBA, GO:0006917=IBA, GO:0003677=IDA, GO:0006417=IDA, GO:0006974=IBA, GO:0001547=IBA, GO:0043565=IDA, GO:0016020=IEA, GO:0008543=TAS, GO:0045648=IDA, GO:0045087=TAS, GO:0005654=TAS, GO:0045893=IDA, GO:0008134=IBA} DNA damage response, signal transduction by p53 class mediator, antral ovarian follicle growth, apoptotic process, embryo development, epidermal growth factor receptor signaling pathway, fibroblast growth factor receptor signaling pathway, glucose homeostasis, induction of apoptosis, initiation of primordial ovarian follicle growth, innate immune response, insulin receptor signaling pathway, negative regulation of transcription from RNA polymerase II promoter, neurotrophin TRK receptor signaling pathway, oocyte maturation, ovulation from ovarian follicle, pattern specification process, phosphatidylinositol-mediated signaling, positive regulation of erythrocyte differentiation, positive regulation of transcription from RNA polymerase II promoter, positive regulation of transcription, DNA-dependent, regulation of cell proliferation, regulation of sequence-specific DNA binding transcription factor activity, regulation of translation, response to DNA damage stimulus, response to stress, tissue development cytoplasm, cytosol, membrane, nucleoplasm, nucleus, transcription factor complex DNA binding, DNA binding, bending, RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity, double-stranded DNA binding, protein binding, protein kinase binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, transcription factor binding Human FOXO4 IntAct UniProtKB {GO:0007095=GO_REF:0000033, GO:0005515=PMID:15126506, GO:0008286=PMID:10217147, GO:0007389=GO_REF:0000033, GO:0008285=PMID:10783894, GO:0003700=PMID:10783894, GO:0006366=PMID:10783894, GO:0003705=GO_REF:0000033, GO:0005634=PMID:22972301, GO:0048513=GO_REF:0000033, GO:0009790=GO_REF:0000033, GO:0005829=PMID:22972301, GO:0051090=GO_REF:0000033, GO:0005737=PMID:16964248, GO:0003690=GO_REF:0000033, GO:0007173=Reactome:REACT_9417, GO:0045944=GO_REF:0000033, GO:0009888=GO_REF:0000033, GO:0007050=PMID:10783894, GO:0000080=PMID:10783894, GO:0005667=GO_REF:0000033, GO:0048011=Reactome:REACT_11061, GO:0006355=PMID:15126506, GO:0019901=GO_REF:0000033, GO:0051151=PMID:16054032, GO:0008301=GO_REF:0000033, GO:0048015=Reactome:REACT_12464, GO:0003677=PMID:10783894, GO:0048863=PMID:22972301, GO:0043565=PMID:22972301, GO:0007517=GO_REF:0000037, GO:0008543=Reactome:REACT_9470, GO:0045087=Reactome:REACT_6802, GO:0016525=PMID:12761217, GO:0001071=PMID:22972301, GO:0005654=Reactome:REACT_147827, GO:0019899=PMID:16964248, GO:0008134=PMID:16054032} P98177 Forkhead box protein O4 protein 20130415 {GO:0007095=IBA, GO:0005515=IPI, GO:0008286=IDA, GO:0007389=IBA, GO:0008285=IDA, GO:0003700=IDA, GO:0006366=TAS, GO:0003705=IBA, GO:0005634=TAS, GO:0048513=IBA, GO:0009790=IBA, GO:0005829=TAS, GO:0051090=IBA, GO:0005737=IDA, GO:0003690=IBA, GO:0007173=TAS, GO:0045944=IBA, GO:0009888=IBA, GO:0007050=IDA, GO:0000080=IDA, GO:0005667=IBA, GO:0048011=TAS, GO:0006355=IDA, GO:0019901=IBA, GO:0051151=IDA, GO:0008301=IBA, GO:0048015=TAS, GO:0003677=IDA, GO:0048863=IMP, GO:0043565=IMP, GO:0007517=IEA, GO:0008543=TAS, GO:0045087=TAS, GO:0016525=IDA, GO:0001071=IMP, GO:0005654=TAS, GO:0019899=IPI, GO:0008134=IPI} G1 phase of mitotic cell cycle, cell cycle arrest, embryo development, epidermal growth factor receptor signaling pathway, fibroblast growth factor receptor signaling pathway, innate immune response, insulin receptor signaling pathway, mitotic G2 DNA damage checkpoint, muscle organ development, negative regulation of angiogenesis, negative regulation of cell proliferation, negative regulation of smooth muscle cell differentiation, neurotrophin TRK receptor signaling pathway, organ development, pattern specification process, phosphatidylinositol-mediated signaling, positive regulation of transcription from RNA polymerase II promoter, regulation of sequence-specific DNA binding transcription factor activity, regulation of transcription, DNA-dependent, stem cell differentiation, tissue development, transcription from RNA polymerase II promoter cytoplasm, cytosol, nucleoplasm, nucleus, transcription factor complex DNA binding, DNA binding, bending, RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity, double-stranded DNA binding, enzyme binding, nucleic acid binding transcription factor activity, protein binding, protein kinase binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, transcription factor binding Human UniProtKB:Q96EB6 FOXP1 HPA UniProtKB {GO:0007389=GO_REF:0000033, GO:0003700=GO_REF:0000002, GO:0030324=GO_REF:0000019, GO:0003705=GO_REF:0000033, GO:0060043=GO_REF:0000019, GO:0005634=GO_REF:0000052, GO:0009790=GO_REF:0000033, GO:0021517=GO_REF:0000019, GO:0046872=GO_REF:0000037, GO:0042803=GO_REF:0000033, GO:0051090=GO_REF:0000033, GO:0005737=GO_REF:0000033, GO:0003690=GO_REF:0000033, GO:0002639=GO_REF:0000033, GO:0060501=GO_REF:0000033, GO:0045944=GO_REF:0000019, GO:0048745=GO_REF:0000033, GO:0002329=GO_REF:0000033, GO:0055007=GO_REF:0000033, GO:0050679=GO_REF:0000019, GO:0005667=GO_REF:0000033, GO:0033152=GO_REF:0000033, GO:0046982=GO_REF:0000033, GO:0008301=GO_REF:0000033, GO:0005730=GO_REF:0000052, GO:0045214=GO_REF:0000019, GO:0002053=GO_REF:0000033, GO:0003677=GO_REF:0000019, GO:0001701=GO_REF:0000019, GO:2000727=GO_REF:0000019, GO:0043565=GO_REF:0000002, GO:0008045=GO_REF:0000019, GO:0007519=GO_REF:0000033, GO:0003682=GO_REF:0000033, GO:0045892=PMID:20950788, GO:0008134=GO_REF:0000033} Q9H334 Forkhead box protein P1 protein 20080205 {GO:0007389=IBA, GO:0003700=IEA, GO:0030324=IEA, GO:0003705=IBA, GO:0060043=IEA, GO:0005634=IDA, GO:0009790=IBA, GO:0021517=IEA, GO:0046872=IEA, GO:0042803=IBA, GO:0051090=IBA, GO:0005737=IBA, GO:0003690=IBA, GO:0002639=IBA, GO:0060501=IBA, GO:0045944=IEA, GO:0048745=IBA, GO:0002329=IBA, GO:0055007=IBA, GO:0050679=IEA, GO:0005667=IBA, GO:0033152=IBA, GO:0046982=IBA, GO:0008301=IBA, GO:0005730=IDA, GO:0045214=IEA, GO:0002053=IBA, GO:0003677=IEA, GO:0001701=IEA, GO:2000727=IEA, GO:0043565=IEA, GO:0008045=IEA, GO:0007519=IBA, GO:0003682=IBA, GO:0045892=IDA, GO:0008134=IBA} cardiac muscle cell differentiation, embryo development, immunoglobulin V(D)J recombination, in utero embryonic development, lung development, motor neuron axon guidance, negative regulation of transcription, DNA-dependent, pattern specification process, positive regulation of cardiac muscle cell differentiation, positive regulation of epithelial cell proliferation, positive regulation of epithelial cell proliferation involved in lung morphogenesis, positive regulation of immunoglobulin production, positive regulation of mesenchymal cell proliferation, positive regulation of transcription from RNA polymerase II promoter, pre-B cell differentiation, regulation of cardiac muscle cell proliferation, regulation of sequence-specific DNA binding transcription factor activity, sarcomere organization, skeletal muscle tissue development, smooth muscle tissue development, ventral spinal cord development cytoplasm, nucleolus, nucleus, transcription factor complex DNA binding, DNA binding, bending, RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity, chromatin binding, double-stranded DNA binding, metal ion binding, protein heterodimerization activity, protein homodimerization activity, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, transcription factor binding NOT Human FOXP2 InterPro UniProtKB {GO:0007389=GO_REF:0000033, GO:0021987=PMID:18987363, GO:0003700=GO_REF:0000002, GO:0003705=GO_REF:0000033, GO:0009790=GO_REF:0000033, GO:0009791=GO_REF:0000033, GO:0042803=PMID:16407075, GO:0046872=GO_REF:0000037, GO:0051090=GO_REF:0000033, GO:0005737=GO_REF:0000033, GO:0003690=GO_REF:0000033, GO:0048745=GO_REF:0000033, GO:0060501=GO_REF:0000033, GO:0043010=GO_REF:0000033, GO:0005667=GO_REF:0000033, GO:0046982=GO_REF:0000033, GO:0048286=GO_REF:0000033, GO:0008301=GO_REF:0000033, GO:0002053=GO_REF:0000033, GO:0021549=GO_REF:0000033, GO:0003677=PMID:16407075, GO:0043565=GO_REF:0000002, GO:0007519=GO_REF:0000033, GO:0003682=GO_REF:0000033, GO:0042297=GO_REF:0000033, GO:0045892=PMID:18987363, GO:0040007=GO_REF:0000033, GO:0021757=PMID:11872605, GO:0060013=GO_REF:0000033, GO:0021758=PMID:11872605, GO:0008134=GO_REF:0000033} Q0PRL4 Forkhead box P2 variant 3 protein 20130413 {GO:0007389=IBA, GO:0021987=IEP, GO:0003700=IEA, GO:0003705=IBA, GO:0009790=IBA, GO:0009791=IBA, GO:0042803=IDA, GO:0046872=IEA, GO:0051090=IBA, GO:0005737=IBA, GO:0003690=IBA, GO:0048745=IBA, GO:0060501=IBA, GO:0043010=IBA, GO:0005667=IBA, GO:0046982=IBA, GO:0048286=IBA, GO:0008301=IBA, GO:0002053=IBA, GO:0021549=IBA, GO:0003677=IDA, GO:0043565=IEA, GO:0007519=IBA, GO:0003682=IBA, GO:0042297=IBA, GO:0045892=IDA, GO:0040007=IBA, GO:0021757=IMP, GO:0060013=IBA, GO:0021758=IMP, GO:0008134=IBA} camera-type eye development, caudate nucleus development, cerebellum development, cerebral cortex development, embryo development, growth, lung alveolus development, negative regulation of transcription, DNA-dependent, pattern specification process, positive regulation of epithelial cell proliferation involved in lung morphogenesis, positive regulation of mesenchymal cell proliferation, post-embryonic development, putamen development, regulation of sequence-specific DNA binding transcription factor activity, righting reflex, skeletal muscle tissue development, smooth muscle tissue development, vocal learning cytoplasm, transcription factor complex DNA binding, DNA binding, bending, RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity, chromatin binding, double-stranded DNA binding, metal ion binding, protein heterodimerization activity, protein homodimerization activity, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, transcription factor binding Human InterPro:IPR001766|InterPro:IPR018122 FOXP3 BHF-UCL UniProtKB {GO:0005515=PMID:20676092, GO:0048302=GO_REF:0000033, GO:0007389=GO_REF:0000033, GO:0032753=GO_REF:0000019, GO:0003700=PMID:11483607, GO:0032693=PMID:15466453, GO:0032715=GO_REF:0000033, GO:0003705=GO_REF:0000033, GO:0002513=GO_REF:0000033, GO:0032714=GO_REF:0000033, GO:0032713=PMID:15466453, GO:0032792=PMID:16652169, GO:0009790=GO_REF:0000033, GO:0048294=GO_REF:0000033, GO:0009791=GO_REF:0000033, GO:0001816=GO_REF:0000019, GO:0042803=PMID:16920951, GO:0042130=PMID:15466453, GO:0032914=GO_REF:0000033, GO:0003690=GO_REF:0000033, GO:0045077=GO_REF:0000033, GO:0048745=GO_REF:0000033, GO:0060501=GO_REF:0000033, GO:0002361=GO_REF:0000019, GO:0043029=PMID:11483607, GO:0002262=GO_REF:0000033, GO:0032689=PMID:15466453, GO:0035035=PMID:17360565, GO:0046982=GO_REF:0000033, GO:0048286=GO_REF:0000033, GO:0008301=GO_REF:0000033, GO:0003714=GO_REF:0000033, GO:0032720=GO_REF:0000033, GO:0002725=PMID:15466453, GO:0021549=GO_REF:0000033, GO:0045085=PMID:16873067, GO:0043234=PMID:16903909, GO:0042110=PMID:15466453, GO:0050777=PMID:15652505, GO:0007519=GO_REF:0000033, GO:0002669=GO_REF:0000033, GO:0008270=GO_REF:0000002, GO:0045893=PMID:19276356, GO:0042297=GO_REF:0000033, GO:0045892=PMID:17360565, GO:0040007=GO_REF:0000033, GO:0002456=GO_REF:0000019, GO:0050852=GO_REF:0000033, GO:0032831=GO_REF:0000033, GO:0001782=GO_REF:0000033, GO:0021987=GO_REF:0000033, GO:0008285=PMID:15652505, GO:0042826=PMID:17360565, GO:0051525=PMID:16873067, GO:0046007=PMID:11483607, GO:0005634=PMID:11483607, GO:0050710=PMID:11483607, GO:0035067=GO_REF:0000033, GO:0035066=PMID:19276356, GO:0043433=PMID:16873067, GO:0005737=GO_REF:0000033, GO:0045944=PMID:19276356, GO:0002677=GO_REF:0000033, GO:0006338=PMID:16903909, GO:0043010=GO_REF:0000033, GO:0032703=PMID:17360565, GO:0005667=GO_REF:0000033, GO:0006355=PMID:11138001, GO:0051059=PMID:16652169, GO:0002851=GO_REF:0000033, GO:0002053=GO_REF:0000033, GO:0032088=PMID:16652169, GO:0009615=PMID:20583921, GO:0033092=GO_REF:0000033, GO:0042036=PMID:11483607, GO:0043565=PMID:19276356, GO:0031064=PMID:19276356, GO:0003682=GO_REF:0000033, GO:0021757=GO_REF:0000033, GO:0060013=GO_REF:0000033, GO:0021758=GO_REF:0000033} Q9BZS1 Forkhead box protein P3 protein 20090803 {GO:0005515=IPI, GO:0048302=IBA, GO:0007389=IBA, GO:0032753=IEA, GO:0003700=IDA, GO:0032693=IDA, GO:0032715=IBA, GO:0003705=IBA, GO:0002513=IBA, GO:0032714=IBA, GO:0032713=IDA, GO:0032792=IDA, GO:0009790=IBA, GO:0048294=IBA, GO:0009791=IBA, GO:0001816=IEA, GO:0042803=IPI, GO:0042130=IDA, GO:0032914=IBA, GO:0003690=IBA, GO:0045077=IBA, GO:0048745=IRD, GO:0060501=IRD, GO:0002361=IEA, GO:0043029=NAS, GO:0002262=IBA, GO:0032689=IDA, GO:0035035=IPI, GO:0046982=IBA, GO:0048286=IRD, GO:0008301=IBA, GO:0003714=IBA, GO:0032720=IBA, GO:0002725=IDA, GO:0021549=IBA, GO:0045085=IMP, GO:0043234=NAS, GO:0042110=IDA, GO:0050777=IDA, GO:0007519=IRD, GO:0002669=IBA, GO:0008270=IEA, GO:0045893=IMP, GO:0042297=IRD, GO:0045892=IDA, GO:0040007=IRD, GO:0002456=IEA, GO:0050852=IBA, GO:0032831=IBA, GO:0001782=IBA, GO:0021987=IRD, GO:0008285=IDA, GO:0042826=IPI, GO:0051525=IPI, GO:0046007=NAS, GO:0005634=IDA, GO:0050710=IDA, GO:0035067=IBA, GO:0035066=IMP, GO:0043433=IDA, GO:0005737=IBA, GO:0045944=IMP, GO:0002677=IBA, GO:0006338=NAS, GO:0043010=IRD, GO:0032703=IDA, GO:0005667=IBA, GO:0006355=NAS, GO:0051059=NAS, GO:0002851=IBA, GO:0002053=IRD, GO:0032088=IDA, GO:0009615=IEP, GO:0033092=IBA, GO:0042036=IDA, GO:0043565=IDA, GO:0031064=IGI, GO:0003682=IBA, GO:0021757=IRD, GO:0060013=IRD, GO:0021758=IRD} B cell homeostasis, CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation, T cell activation, T cell homeostasis, T cell mediated immunity, T cell receptor signaling pathway, camera-type eye development, caudate nucleus development, cerebellum development, cerebral cortex development, chromatin remodeling, cytokine production, embryo development, growth, lung alveolus development, myeloid cell homeostasis, negative regulation of CREB transcription factor activity, negative regulation of NF-kappaB transcription factor activity, negative regulation of T cell cytokine production, negative regulation of T cell proliferation, negative regulation of activated T cell proliferation, negative regulation of cell proliferation, negative regulation of chronic inflammatory response, negative regulation of cytokine biosynthetic process, negative regulation of cytokine secretion, negative regulation of histone acetylation, negative regulation of histone deacetylation, negative regulation of immune response, negative regulation of interferon-gamma biosynthetic process, negative regulation of interferon-gamma production, negative regulation of interleukin-10 production, negative regulation of interleukin-2 biosynthetic process, negative regulation of interleukin-2 production, negative regulation of interleukin-4 production, negative regulation of interleukin-5 production, negative regulation of interleukin-6 production, negative regulation of isotype switching to IgE isotypes, negative regulation of sequence-specific DNA binding transcription factor activity, negative regulation of transcription, DNA-dependent, negative regulation of tumor necrosis factor production, pattern specification process, positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation, positive regulation of T cell anergy, positive regulation of epithelial cell proliferation involved in lung morphogenesis, positive regulation of histone acetylation, positive regulation of immature T cell proliferation in thymus, positive regulation of interleukin-4 production, positive regulation of mesenchymal cell proliferation, positive regulation of peripheral T cell tolerance induction, positive regulation of transcription from RNA polymerase II promoter, positive regulation of transcription, DNA-dependent, positive regulation of transforming growth factor beta1 production, post-embryonic development, putamen development, regulation of isotype switching to IgG isotypes, regulation of transcription, DNA-dependent, response to virus, righting reflex, skeletal muscle tissue development, smooth muscle tissue development, tolerance induction to self antigen, vocal learning cytoplasm, nucleus, protein complex, transcription factor complex DNA binding, bending, NF-kappaB binding, NFAT protein binding, RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity, chromatin binding, double-stranded DNA binding, histone acetyltransferase binding, histone deacetylase binding, protein binding, protein heterodimerization activity, protein homodimerization activity, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, transcription corepressor activity, zinc ion binding Human UniProtKB:P56524 FOXP4 RefGenome UniProtKB {GO:0005667=GO_REF:0000033, GO:0007389=GO_REF:0000033, GO:0003700=GO_REF:0000002, GO:0046982=GO_REF:0000033, GO:0008301=GO_REF:0000033, GO:0003705=GO_REF:0000033, GO:0042803=GO_REF:0000033, GO:0046872=GO_REF:0000037, GO:0043565=GO_REF:0000002, GO:0007507=GO_REF:0000033, GO:0051090=GO_REF:0000033, GO:0005737=GO_REF:0000033, GO:0003690=GO_REF:0000033, GO:0003682=GO_REF:0000033, GO:0048617=GO_REF:0000033, GO:0009888=GO_REF:0000033, GO:0008134=GO_REF:0000033} Q8IVH2 Forkhead box protein P4 protein 20100514 {GO:0005667=IBA, GO:0007389=IBA, GO:0003700=IEA, GO:0046982=IBA, GO:0008301=IBA, GO:0003705=IBA, GO:0042803=IBA, GO:0046872=IEA, GO:0043565=IEA, GO:0007507=IBA, GO:0051090=IBA, GO:0005737=IBA, GO:0003690=IBA, GO:0003682=IBA, GO:0048617=IBA, GO:0009888=IBA, GO:0008134=IBA} embryonic foregut morphogenesis, heart development, pattern specification process, regulation of sequence-specific DNA binding transcription factor activity, tissue development cytoplasm, transcription factor complex DNA binding, bending, RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity, chromatin binding, double-stranded DNA binding, metal ion binding, protein heterodimerization activity, protein homodimerization activity, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, transcription factor binding Human PANTHER:PTN000215024 FOXQ1 RefGenome UniProtKB {GO:0005667=GO_REF:0000033, GO:0007389=GO_REF:0000033, GO:0008301=GO_REF:0000033, GO:0003705=GO_REF:0000033, GO:0030331=GO_REF:0000033, GO:0009790=GO_REF:0000033, GO:0031069=GO_REF:0000033, GO:0043280=GO_REF:0000033, GO:0043565=GO_REF:0000002, GO:0051090=GO_REF:0000033, GO:0003690=GO_REF:0000033, GO:0006309=GO_REF:0000033, GO:0045944=GO_REF:0000033, GO:0031624=GO_REF:0000033, GO:0043028=GO_REF:0000033, GO:0008134=GO_REF:0000033} Q9C009 Forkhead box protein Q1 protein 20100514 {GO:0005667=IBA, GO:0007389=IBA, GO:0008301=IBA, GO:0003705=IBA, GO:0030331=IBA, GO:0009790=IBA, GO:0031069=IBA, GO:0043280=IBA, GO:0043565=IEA, GO:0051090=IBA, GO:0003690=IBA, GO:0006309=IBA, GO:0045944=IBA, GO:0031624=IBA, GO:0043028=IBA, GO:0008134=IBA} apoptotic DNA fragmentation, embryo development, hair follicle morphogenesis, pattern specification process, positive regulation of cysteine-type endopeptidase activity involved in apoptotic process, positive regulation of transcription from RNA polymerase II promoter, regulation of sequence-specific DNA binding transcription factor activity transcription factor complex DNA binding, bending, RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity, cysteine-type endopeptidase regulator activity involved in apoptotic process, double-stranded DNA binding, estrogen receptor binding, sequence-specific DNA binding, transcription factor binding, ubiquitin conjugating enzyme binding Human PANTHER:PTN000215024 FOXRED1 LIFEdb UniProtKB {GO:0005739=GO_REF:0000054, GO:0008150=GO_REF:0000015, GO:0016491=GO_REF:0000037, GO:0016021=GO_REF:0000037} Q96CU9 FAD-dependent oxidoreductase domain-containing protein 1 protein 20100607 {GO:0005739=IDA, GO:0008150=ND, GO:0016491=IEA, GO:0016021=IEA} biological_process integral to membrane, mitochondrion oxidoreductase activity Human FOXRED2 UniProtKB UniProtKB {GO:0005515=PMID:19706418, GO:0050660=PMID:19706418, GO:0016491=GO_REF:0000037, GO:0005788=PMID:19706418, GO:0030433=PMID:19706418} Q8IWF2 FAD-dependent oxidoreductase domain-containing protein 2 protein 20110128 {GO:0005515=IPI, GO:0050660=IDA, GO:0016491=IEA, GO:0005788=IDA, GO:0030433=IMP} ER-associated protein catabolic process endoplasmic reticulum lumen flavin adenine dinucleotide binding, oxidoreductase activity, protein binding Human UniProtKB:Q13438-2 FOXS1 UniProtKB UniProtKB {GO:0001656=GO_REF:0000033, GO:0008286=GO_REF:0000033, GO:0001657=GO_REF:0000033, GO:0003700=PMID:9325056, GO:0055010=GO_REF:0000033, GO:0003705=GO_REF:0000033, GO:0001756=GO_REF:0000033, GO:0005634=GO_REF:0000024, GO:0048844=GO_REF:0000033, GO:0048703=GO_REF:0000033, GO:0043433=GO_REF:0000024, GO:0001946=GO_REF:0000033, GO:0014034=GO_REF:0000033, GO:0050880=GO_REF:0000033, GO:0003690=GO_REF:0000033, GO:0007219=GO_REF:0000033, GO:0030199=GO_REF:0000033, GO:0045944=GO_REF:0000033, GO:0050885=GO_REF:0000033, GO:0043010=GO_REF:0000033, GO:0040018=GO_REF:0000033, GO:0048010=GO_REF:0000033, GO:0005667=GO_REF:0000033, GO:0046620=GO_REF:0000033, GO:0006355=GO_REF:0000029, GO:0001569=GO_REF:0000033, GO:0001568=GO_REF:0000024, GO:0035050=GO_REF:0000033, GO:0008301=GO_REF:0000033, GO:0007275=GO_REF:0000029, GO:0003677=GO_REF:0000024, GO:0060038=GO_REF:0000033, GO:0031490=GO_REF:0000033, GO:0043565=GO_REF:0000002, GO:0001503=GO_REF:0000033, GO:0001974=GO_REF:0000033, GO:0048343=GO_REF:0000033, GO:0045892=GO_REF:0000024, GO:0001570=GO_REF:0000033, GO:0008134=GO_REF:0000033} O43638 Forkhead box protein S1 protein 20091127 {GO:0001656=IRD, GO:0008286=IBA, GO:0001657=IRD, GO:0003700=TAS, GO:0055010=IBA, GO:0003705=IBA, GO:0001756=IBA, GO:0005634=ISS, GO:0048844=IBA, GO:0048703=IRD, GO:0043433=ISS, GO:0001946=IBA, GO:0014034=IBA, GO:0050880=IBA, GO:0003690=IBA, GO:0007219=IBA, GO:0030199=IBA, GO:0045944=IBA, GO:0050885=IBA, GO:0043010=IBA, GO:0040018=IBA, GO:0048010=IBA, GO:0005667=IBA, GO:0046620=IBA, GO:0006355=NAS, GO:0001569=IBA, GO:0001568=ISS, GO:0035050=IBA, GO:0008301=IBA, GO:0007275=NAS, GO:0003677=ISS, GO:0060038=IBA, GO:0031490=IBA, GO:0043565=IEA, GO:0001503=IBA, GO:0001974=IBA, GO:0048343=IBA, GO:0045892=ISS, GO:0001570=IBA, GO:0008134=IBA} Notch signaling pathway, artery morphogenesis, blood vessel development, blood vessel remodeling, camera-type eye development, cardiac muscle cell proliferation, collagen fibril organization, embryonic heart tube development, embryonic viscerocranium morphogenesis, insulin receptor signaling pathway, lymphangiogenesis, metanephros development, multicellular organismal development, negative regulation of sequence-specific DNA binding transcription factor activity, negative regulation of transcription, DNA-dependent, neural crest cell fate commitment, neuromuscular process controlling balance, ossification, paraxial mesodermal cell fate commitment, patterning of blood vessels, positive regulation of multicellular organism growth, positive regulation of transcription from RNA polymerase II promoter, regulation of blood vessel size, regulation of organ growth, regulation of transcription, DNA-dependent, somitogenesis, ureteric bud development, vascular endothelial growth factor receptor signaling pathway, vasculogenesis, ventricular cardiac muscle tissue morphogenesis nucleus, transcription factor complex DNA binding, DNA binding, bending, RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity, chromatin DNA binding, double-stranded DNA binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, transcription factor binding Human UniProtKB:Q61574 FPGS InterPro UniProtKB {GO:0031100=GO_REF:0000019, GO:0005743=GO_REF:0000039, GO:0006767=Reactome:REACT_11238, GO:0044281=Reactome:REACT_111217, GO:0005524=GO_REF:0000002, GO:0042221=GO_REF:0000019, GO:0004326=GO_REF:0000002, GO:0005829=Reactome:REACT_11098, GO:0001889=GO_REF:0000019, GO:0005739=PMID:7721888, GO:0005737=PMID:1409616, GO:0006139=PMID:7721888, GO:0006766=Reactome:REACT_11193, GO:0007420=GO_REF:0000019, GO:0005759=Reactome:REACT_11134, GO:0046655=Reactome:REACT_11167, GO:0006730=GO_REF:0000037} Q5JU23 Folylpolyglutamate synthase, mitochondrial protein 20130413 {GO:0031100=IEA, GO:0005743=IEA, GO:0006767=TAS, GO:0044281=TAS, GO:0005524=IEA, GO:0042221=IEA, GO:0004326=IEA, GO:0005829=TAS, GO:0001889=IEA, GO:0005739=TAS, GO:0005737=TAS, GO:0006139=TAS, GO:0006766=TAS, GO:0007420=IEA, GO:0005759=TAS, GO:0046655=TAS, GO:0006730=IEA} brain development, folic acid metabolic process, liver development, nucleobase-containing compound metabolic process, one-carbon metabolic process, organ regeneration, response to chemical stimulus, small molecule metabolic process, vitamin metabolic process, water-soluble vitamin metabolic process cytoplasm, cytosol, mitochondrial inner membrane, mitochondrial matrix, mitochondrion ATP binding, tetrahydrofolylpolyglutamate synthase activity Human InterPro:IPR001645|InterPro:IPR013221|InterPro:IPR018109 FPGT PINC UniProtKB {GO:0005737=GO_REF:0000039, GO:0047341=GO_REF:0000003, GO:0016779=GO_REF:0000038, GO:0006004=PMID:9804772, GO:0003824=PMID:9804772, GO:0005525=GO_REF:0000037, GO:0016772=GO_REF:0000002} O14772 Fucose-1-phosphate guanylyltransferase protein 20030904 {GO:0005737=IEA, GO:0047341=IEA, GO:0016779=IEA, GO:0006004=TAS, GO:0003824=TAS, GO:0005525=IEA, GO:0016772=IEA} fucose metabolic process cytoplasm GTP binding, catalytic activity, fucose-1-phosphate guanylyltransferase activity, nucleotidyltransferase activity, transferase activity, transferring phosphorus-containing groups Human FPR1 IntAct UniProtKB {GO:0005515=PMID:22447027, GO:0042554=GO_REF:0000002, GO:0007263=PMID:10861041, GO:0005886=Reactome:REACT_22289, GO:0006928=PMID:10882119, GO:0004982=PMID:12218158, GO:0000187=PMID:10857861, GO:0007165=PMID:10820279, GO:0006935=GO_REF:0000037, GO:0007186=PMID:10823817, GO:0007188=PMID:10889468, GO:0004872=PMID:10857861, GO:0016021=GO_REF:0000037, GO:0005768=PMID:10823817} P21462 fMet-Leu-Phe receptor protein 20130415 {GO:0005515=IPI, GO:0042554=IEA, GO:0007263=TAS, GO:0005886=TAS, GO:0006928=TAS, GO:0004982=IDA, GO:0000187=TAS, GO:0007165=TAS, GO:0006935=IEA, GO:0007186=TAS, GO:0007188=TAS, GO:0004872=TAS, GO:0016021=IEA, GO:0005768=TAS} G-protein coupled receptor signaling pathway, activation of MAPK activity, adenylate cyclase-modulating G-protein coupled receptor signaling pathway, cellular component movement, chemotaxis, nitric oxide mediated signal transduction, signal transduction, superoxide anion generation endosome, integral to membrane, plasma membrane N-formyl peptide receptor activity, protein binding, receptor activity Human UniProtKB:P25098 FPR2 Reactome UniProtKB {GO:0042554=GO_REF:0000002, GO:0004982=GO_REF:0000002, GO:0006954=GO_REF:0000002, GO:0005886=Reactome:REACT_22436, GO:0007186=PMID:9054386, GO:0006935=GO_REF:0000037, GO:0004930=PMID:9054386, GO:0006928=PMID:1374236, GO:0016021=GO_REF:0000037, GO:0007155=PMID:9054386} P25090 N-formyl peptide receptor 2 protein 20091023 {GO:0042554=IEA, GO:0004982=IEA, GO:0006954=IEA, GO:0005886=TAS, GO:0007186=TAS, GO:0006935=IEA, GO:0004930=TAS, GO:0006928=TAS, GO:0016021=IEA, GO:0007155=TAS} G-protein coupled receptor signaling pathway, cell adhesion, cellular component movement, chemotaxis, inflammatory response, superoxide anion generation integral to membrane, plasma membrane G-protein coupled receptor activity, N-formyl peptide receptor activity Human FRA10AC1 IntAct UniProtKB {GO:0005515=PMID:16169070, GO:0005634=GO_REF:0000039} Q70Z53 Protein FRA10AC1 protein 20130415 {GO:0005515=IPI, GO:0005634=IEA} nucleus protein binding Human UniProtKB:Q12852 FRAS1 BHF-UCL UniProtKB {GO:0031012=PMID:22261194, GO:0007154=GO_REF:0000002, GO:0005886=GO_REF:0000039, GO:0016021=GO_REF:0000037, GO:0046872=GO_REF:0000037} Q86XX4 Extracellular matrix protein FRAS1 protein 20120228 {GO:0031012=ISS, GO:0007154=IEA, GO:0005886=IEA, GO:0016021=IEA, GO:0046872=IEA} cell communication extracellular matrix, integral to membrane, plasma membrane metal ion binding colocalizes_with Human UniProtKB:F1RYS0 FRAT1 UniProtKB UniProtKB {GO:0005737=GO_REF:0000039, GO:0016055=GO_REF:0000037} Q92837 Proto-oncogene FRAT1 protein 20130413 {GO:0005737=IEA, GO:0016055=IEA} Wnt receptor signaling pathway cytoplasm Human UniProtKB-SubCell:SL-0086 FRAT2 UniProtKB UniProtKB {GO:0003674=GO_REF:0000015, GO:0008283=PMID:9635432, GO:0007275=PMID:9635432, GO:0005575=GO_REF:0000015, GO:0016055=GO_REF:0000037} O75474 GSK-3-binding protein FRAT2 protein 20061026 {GO:0003674=ND, GO:0008283=NAS, GO:0007275=NAS, GO:0005575=ND, GO:0016055=IEA} Wnt receptor signaling pathway, cell proliferation, multicellular organismal development cellular_component molecular_function Human FREM1 UniProtKB UniProtKB {GO:0007154=GO_REF:0000002, GO:0007160=GO_REF:0000019, GO:0030246=GO_REF:0000002, GO:0016021=GO_REF:0000002, GO:0097094=PMID:21931569, GO:0046872=GO_REF:0000037, GO:0005604=GO_REF:0000039} Q5H8C1 FRAS1-related extracellular matrix protein 1 protein 20120426 {GO:0007154=IEA, GO:0007160=IEA, GO:0030246=IEA, GO:0016021=IEA, GO:0097094=IMP, GO:0046872=IEA, GO:0005604=IEA} cell communication, cell-matrix adhesion, craniofacial suture morphogenesis basement membrane, integral to membrane carbohydrate binding, metal ion binding Human FREM2 UniProtKB UniProtKB {GO:0048839=GO_REF:0000019, GO:0007154=GO_REF:0000002, GO:0005886=GO_REF:0000039, GO:0005509=GO_REF:0000002, GO:0016021=GO_REF:0000037, GO:0002009=GO_REF:0000019, GO:0007156=GO_REF:0000002, GO:0005604=GO_REF:0000019} Q5SZK8 FRAS1-related extracellular matrix protein 2 protein 20130413 {GO:0048839=IEA, GO:0007154=IEA, GO:0005886=IEA, GO:0005509=IEA, GO:0016021=IEA, GO:0002009=IEA, GO:0007156=IEA, GO:0005604=IEA} cell communication, homophilic cell adhesion, inner ear development, morphogenesis of an epithelium basement membrane, integral to membrane, plasma membrane calcium ion binding Human UniProtKB-SubCell:SL-0039 FRG1 UniProtKB UniProtKB {GO:0015030=GO_REF:0000039, GO:0016607=GO_REF:0000039, GO:0000398=PMID:11991638, GO:0006364=GO_REF:0000037, GO:0005730=GO_REF:0000039, GO:0071013=PMID:11991638} Q14331 Protein FRG1 protein 20110302 {GO:0015030=IEA, GO:0016607=IEA, GO:0000398=IC, GO:0006364=IEA, GO:0005730=IEA, GO:0071013=IDA} mRNA splicing, via spliceosome, rRNA processing Cajal body, catalytic step 2 spliceosome, nuclear speck, nucleolus Human FRK IntAct UniProtKB {GO:0005622=PMID:7510261, GO:0005515=PMID:19345329, GO:0005737=GO_REF:0000039, GO:0008285=PMID:7664264, GO:0005886=GO_REF:0000019, GO:0006468=PMID:7696183, GO:0005634=GO_REF:0000039, GO:0004713=GO_REF:0000038, GO:0004715=GO_REF:0000003, GO:0005524=GO_REF:0000037, GO:0030154=GO_REF:0000019} P42685 Tyrosine-protein kinase FRK protein 20130415 {GO:0005622=TAS, GO:0005515=IPI, GO:0005737=IEA, GO:0008285=TAS, GO:0005886=IEA, GO:0006468=TAS, GO:0005634=IEA, GO:0004713=IEA, GO:0004715=IEA, GO:0005524=IEA, GO:0030154=IEA} cell differentiation, negative regulation of cell proliferation, protein phosphorylation cytoplasm, intracellular, nucleus, plasma membrane ATP binding, non-membrane spanning protein tyrosine kinase activity, protein binding, protein tyrosine kinase activity Human UniProtKB:P60484 FRMD4A UniProtKB UniProtKB {GO:0090162=GO_REF:0000019, GO:0005737=GO_REF:0000037, GO:0005923=GO_REF:0000019, GO:0030674=GO_REF:0000019, GO:0005856=GO_REF:0000039} Q9P2Q2 FERM domain-containing protein 4A protein 20130413 {GO:0090162=IEA, GO:0005737=IEA, GO:0005923=IEA, GO:0030674=IEA, GO:0005856=IEA} establishment of epithelial cell polarity cytoplasm, cytoskeleton, tight junction protein binding, bridging Human UniProtKB-SubCell:SL-0090 FRMD4B UniProtKB UniProtKB {GO:0090162=GO_REF:0000019, GO:0005737=GO_REF:0000019, GO:0005856=GO_REF:0000039, GO:0001726=GO_REF:0000019} Q9Y2L6 FERM domain-containing protein 4B protein 20130413 {GO:0090162=IEA, GO:0005737=IEA, GO:0005856=IEA, GO:0001726=IEA} establishment of epithelial cell polarity cytoplasm, cytoskeleton, ruffle Human UniProtKB-SubCell:SL-0090 FRMD5 BHF-UCL UniProtKB {GO:0008092=GO_REF:0000002, GO:0003674=GO_REF:0000015, GO:0008150=GO_REF:0000015, GO:0005737=GO_REF:0000002, GO:0005575=GO_REF:0000015, GO:0016021=GO_REF:0000037, GO:0005856=GO_REF:0000002, GO:0019898=GO_REF:0000002} Q7Z6J6 FERM domain-containing protein 5 protein 20110712 {GO:0008092=IEA, GO:0003674=ND, GO:0008150=ND, GO:0005737=IEA, GO:0005575=ND, GO:0016021=IEA, GO:0005856=IEA, GO:0019898=IEA} biological_process cellular_component, cytoplasm, cytoskeleton, extrinsic to membrane, integral to membrane cytoskeletal protein binding, molecular_function Human FRMD6 HPA UniProtKB {GO:0005739=GO_REF:0000052, GO:0043296=GO_REF:0000019, GO:0003383=GO_REF:0000019, GO:0032970=GO_REF:0000019, GO:0005886=GO_REF:0000039, GO:0034613=GO_REF:0000019, GO:0005856=GO_REF:0000002} Q96NE9 FERM domain-containing protein 6 protein 20080205 {GO:0005739=IDA, GO:0043296=IEA, GO:0003383=IEA, GO:0032970=IEA, GO:0005886=IEA, GO:0034613=IEA, GO:0005856=IEA} apical constriction, cellular protein localization, regulation of actin filament-based process apical junction complex, cytoskeleton, mitochondrion, plasma membrane Human FRMD8 InterPro UniProtKB {GO:0005856=GO_REF:0000002} Q9BZ67 FERM domain-containing protein 8 protein 20130413 {GO:0005856=IEA} cytoskeleton Human InterPro:IPR000299 FRMPD1 HPA UniProtKB {GO:0005737=GO_REF:0000052, GO:0005886=GO_REF:0000039, GO:0005856=GO_REF:0000002, GO:0005829=GO_REF:0000039} Q5SYB0 FERM and PDZ domain-containing protein 1 protein 20120912 {GO:0005737=IDA, GO:0005886=IEA, GO:0005856=IEA, GO:0005829=IEA} cytoplasm, cytoskeleton, cytosol, plasma membrane Human FRMPD4 UniProtKB UniProtKB {GO:0005515=PMID:19118189, GO:0043197=PMID:19118189, GO:0051835=PMID:19118189, GO:0005546=PMID:19118189, GO:0005856=GO_REF:0000002} Q14CM0 FERM and PDZ domain-containing protein 4 protein 20091109 {GO:0005515=IPI, GO:0043197=IDA, GO:0051835=IMP, GO:0005546=IDA, GO:0005856=IEA} positive regulation of synapse structural plasticity cytoskeleton, dendritic spine phosphatidylinositol-4,5-bisphosphate binding, protein binding Human UniProtKB:P78352 FRS2 Reactome UniProtKB {GO:0008286=Reactome:REACT_498, GO:0005515=PMID:9660748, GO:0005886=Reactome:REACT_147854, GO:0005158=GO_REF:0000002, GO:0046619=GO_REF:0000019, GO:0003281=GO_REF:0000019, GO:0001759=GO_REF:0000019, GO:0007405=GO_REF:0000019, GO:0000187=GO_REF:0000019, GO:0005737=GO_REF:0000019, GO:0000186=Reactome:REACT_12005, GO:0007173=Reactome:REACT_9417, GO:0005068=PMID:9660748, GO:0008595=GO_REF:0000019, GO:0060527=GO_REF:0000019, GO:0050678=GO_REF:0000019, GO:0048011=Reactome:REACT_11061, GO:0005168=PMID:15488758, GO:0048015=Reactome:REACT_12464, GO:0019211=PMID:9660748, GO:0005104=PMID:9660748, GO:0001702=GO_REF:0000019, GO:0012505=GO_REF:0000039, GO:0007186=PMID:9660748, GO:0016020=PMID:9660748, GO:0008543=Reactome:REACT_9470, GO:0005887=PMID:9660748, GO:0045087=Reactome:REACT_6802, GO:0007185=PMID:9660748, GO:0030900=GO_REF:0000019, GO:0005768=Reactome:REACT_12063} Q8WU20 Fibroblast growth factor receptor substrate 2 protein 20070120 {GO:0008286=TAS, GO:0005515=IPI, GO:0005886=TAS, GO:0005158=IEA, GO:0046619=IEA, GO:0003281=IEA, GO:0001759=IEA, GO:0007405=IEA, GO:0000187=IEA, GO:0005737=IEA, GO:0000186=TAS, GO:0007173=TAS, GO:0005068=TAS, GO:0008595=IEA, GO:0060527=IEA, GO:0050678=IEA, GO:0048011=TAS, GO:0005168=IPI, GO:0048015=TAS, GO:0019211=TAS, GO:0005104=IPI, GO:0001702=IEA, GO:0012505=IEA, GO:0007186=TAS, GO:0016020=TAS, GO:0008543=TAS, GO:0005887=TAS, GO:0045087=TAS, GO:0007185=TAS, GO:0030900=IEA, GO:0005768=TAS} G-protein coupled receptor signaling pathway, activation of MAPK activity, activation of MAPKK activity, anterior/posterior axis specification, embryo, epidermal growth factor receptor signaling pathway, fibroblast growth factor receptor signaling pathway, forebrain development, gastrulation with mouth forming second, innate immune response, insulin receptor signaling pathway, neuroblast proliferation, neurotrophin TRK receptor signaling pathway, optic placode formation involved in camera-type eye formation, organ induction, phosphatidylinositol-mediated signaling, prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis, regulation of epithelial cell proliferation, transmembrane receptor protein tyrosine phosphatase signaling pathway, ventricular septum development cytoplasm, endomembrane system, endosome, integral to plasma membrane, membrane, plasma membrane fibroblast growth factor receptor binding, insulin receptor binding, neurotrophin TRKA receptor binding, phosphatase activator activity, protein binding, transmembrane receptor protein tyrosine kinase adaptor activity Human FRS3 Reactome UniProtKB {GO:0007165=PMID:8761293, GO:0005886=Reactome:REACT_111238, GO:0008543=Reactome:REACT_9470, GO:0005158=GO_REF:0000002, GO:0005104=PMID:9660748} O43559 Fibroblast growth factor receptor substrate 3 protein 20100226 {GO:0007165=TAS, GO:0005886=TAS, GO:0008543=TAS, GO:0005158=IEA, GO:0005104=IPI} fibroblast growth factor receptor signaling pathway, signal transduction plasma membrane fibroblast growth factor receptor binding, insulin receptor binding Human FRY UniProtKB UniProtKB {GO:0005737=GO_REF:0000039, GO:0000922=GO_REF:0000039, GO:0005815=GO_REF:0000039} Q5TBA9 Protein furry homolog protein 20130413 {GO:0005737=IEA, GO:0000922=IEA, GO:0005815=IEA} cytoplasm, microtubule organizing center, spindle pole Human UniProtKB-SubCell:SL-0048 FRYL UniProtKB UniProtKB {GO:0006355=GO_REF:0000037, GO:0006351=GO_REF:0000037} O94915 Protein furry homolog-like protein 20130413 {GO:0006355=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent Human UniProtKB-KW:KW-0805 FRZB BHF-UCL UniProtKB {GO:0008406=GO_REF:0000033, GO:0017147=GO_REF:0000024, GO:0060429=GO_REF:0000033, GO:0030308=PMID:20208569, GO:0008285=PMID:20208569, GO:0030178=PMID:20208569, GO:0007409=GO_REF:0000033, GO:0005615=PMID:22261194, GO:0060029=GO_REF:0000019, GO:0005737=GO_REF:0000033, GO:0014033=GO_REF:0000019, GO:0090103=GO_REF:0000033, GO:0016055=GO_REF:0000037, GO:0090090=PMID:17471511, GO:0001944=GO_REF:0000033, GO:0042813=GO_REF:0000033, GO:0010721=GO_REF:0000019, GO:0043065=PMID:18166153, GO:0060056=GO_REF:0000033, GO:0032589=GO_REF:0000033, GO:0030165=GO_REF:0000033, GO:0070367=GO_REF:0000033, GO:0061053=GO_REF:0000019, GO:0001501=PMID:8824257, GO:0016020=PMID:8824257, GO:0007420=GO_REF:0000033, GO:0045600=PMID:12055200, GO:0061037=GO_REF:0000033} Q92765 Secreted frizzled-related protein 3 protein 20120228 {GO:0008406=IBA, GO:0017147=ISS, GO:0060429=IBA, GO:0030308=IDA, GO:0008285=IDA, GO:0030178=IDA, GO:0007409=IRD, GO:0005615=ISS, GO:0060029=IEA, GO:0005737=IBA, GO:0014033=IEA, GO:0090103=IBA, GO:0016055=IEA, GO:0090090=IDA, GO:0001944=IBA, GO:0042813=IBA, GO:0010721=IEA, GO:0043065=IGI, GO:0060056=IBA, GO:0032589=IKR, GO:0030165=IBA, GO:0070367=IBA, GO:0061053=IEA, GO:0001501=TAS, GO:0016020=TAS, GO:0007420=IBA, GO:0045600=IDA, GO:0061037=IBA} Wnt receptor signaling pathway, axonogenesis, brain development, cochlea morphogenesis, convergent extension involved in organogenesis, epithelium development, gonad development, mammary gland involution, negative regulation of Wnt receptor signaling pathway, negative regulation of canonical Wnt receptor signaling pathway, negative regulation of cartilage development, negative regulation of cell development, negative regulation of cell growth, negative regulation of cell proliferation, negative regulation of hepatocyte differentiation, neural crest cell differentiation, positive regulation of apoptotic process, positive regulation of fat cell differentiation, skeletal system development, somite development, vasculature development cytoplasm, extracellular space, membrane, neuron projection membrane PDZ domain binding, Wnt-activated receptor activity, Wnt-protein binding Human UniProtKB:F1RYL4 FSCN1 IntAct UniProtKB {GO:0005515=PMID:21706053, GO:0001725=PMID:3525578, GO:0030054=GO_REF:0000037, GO:0030036=PMID:9571235, GO:0008283=PMID:8068206, GO:0003779=PMID:20393565, GO:0030175=PMID:3525578, GO:0015629=PMID:3525578, GO:0005829=GO_REF:0000039, GO:0005737=GO_REF:0000038, GO:0051015=PMID:17671164, GO:0016477=PMID:20393565, GO:0008144=PMID:20393565, GO:0048870=PMID:9571235, GO:0071437=PMID:20137952, GO:0030674=GO_REF:0000002, GO:0005856=GO_REF:0000040, GO:0051017=PMID:20393565} Q16658 Fascin protein 20130415 {GO:0005515=IPI, GO:0001725=IDA, GO:0030054=IEA, GO:0030036=IDA, GO:0008283=TAS, GO:0003779=IDA, GO:0030175=IDA, GO:0015629=IDA, GO:0005829=IEA, GO:0005737=IEA, GO:0051015=IDA, GO:0016477=IMP, GO:0008144=IDA, GO:0048870=IDA, GO:0071437=IDA, GO:0030674=IEA, GO:0005856=IEA, GO:0051017=IDA} actin cytoskeleton organization, actin filament bundle assembly, cell migration, cell motility, cell proliferation actin cytoskeleton, cell junction, cytoplasm, cytoskeleton, cytosol, filopodium, invadopodium, stress fiber actin binding, actin filament binding, drug binding, protein binding, protein binding, bridging Human UniProtKB:Q9ULL4 FSCN2 PINC UniProtKB {GO:0005737=GO_REF:0000037, GO:0030036=GO_REF:0000024, GO:0051015=GO_REF:0000024, GO:0032420=GO_REF:0000039, GO:0003779=GO_REF:0000024, GO:0015629=GO_REF:0000024, GO:0030674=GO_REF:0000002, GO:0007601=PMID:10783262, GO:0009653=PMID:10783262, GO:0051017=PMID:10783262, GO:0042462=GO_REF:0000019} O14926 Fascin-2 protein 20030904 {GO:0005737=IEA, GO:0030036=ISS, GO:0051015=ISS, GO:0032420=IEA, GO:0003779=ISS, GO:0015629=ISS, GO:0030674=IEA, GO:0007601=TAS, GO:0009653=TAS, GO:0051017=TAS, GO:0042462=IEA} actin cytoskeleton organization, actin filament bundle assembly, anatomical structure morphogenesis, eye photoreceptor cell development, visual perception actin cytoskeleton, cytoplasm, stereocilium actin binding, actin filament binding, protein binding, bridging Human FSD1 HPA UniProtKB {GO:0005622=GO_REF:0000002, GO:0005737=GO_REF:0000052, GO:0007067=GO_REF:0000037, GO:0005815=GO_REF:0000039, GO:0005874=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0032154=GO_REF:0000039, GO:0051301=GO_REF:0000037} Q9BTV5 Fibronectin type III and SPRY domain-containing protein 1 protein 20110516 {GO:0005622=IEA, GO:0005737=IDA, GO:0007067=IEA, GO:0005815=IEA, GO:0005874=IEA, GO:0005634=IEA, GO:0032154=IEA, GO:0051301=IEA} cell division, mitosis cleavage furrow, cytoplasm, intracellular, microtubule, microtubule organizing center, nucleus Human FSD1L UniProtKB UniProtKB {GO:0005622=GO_REF:0000002, GO:0003674=GO_REF:0000015, GO:0008150=GO_REF:0000015, GO:0005575=GO_REF:0000015} Q9BXM9 FSD1-like protein protein 20061026 {GO:0005622=IEA, GO:0003674=ND, GO:0008150=ND, GO:0005575=ND} biological_process cellular_component, intracellular molecular_function Human FSHB BHF-UCL UniProtKB {GO:0005515=PMID:15662415, GO:0008284=PMID:20613903, GO:0007565=PMID:8220432, GO:0030335=PMID:20613903, GO:0006701=PMID:14557487, GO:0046982=GO_REF:0000029, GO:0016913=GO_REF:0000029, GO:0005576=Reactome:REACT_22268, GO:0007283=GO_REF:0000029, GO:0007292=PMID:8220432, GO:0007165=PMID:8220432, GO:0001541=GO_REF:0000029, GO:0005737=PMID:14602737, GO:0005179=PMID:8220432, GO:0016486=Reactome:REACT_15452, GO:0007179=PMID:14557487, GO:0060011=GO_REF:0000019, GO:0044267=Reactome:REACT_17015} P01225 Follitropin subunit beta protein 20120821 {GO:0005515=IPI, GO:0008284=NAS, GO:0007565=TAS, GO:0030335=NAS, GO:0006701=TAS, GO:0046982=NAS, GO:0016913=NAS, GO:0005576=TAS, GO:0007283=NAS, GO:0007292=TAS, GO:0007165=TAS, GO:0001541=NAS, GO:0005737=IDA, GO:0005179=TAS, GO:0016486=TAS, GO:0007179=IEP, GO:0060011=IEA, GO:0044267=TAS} Sertoli cell proliferation, cellular protein metabolic process, female gamete generation, female pregnancy, ovarian follicle development, peptide hormone processing, positive regulation of cell migration, positive regulation of cell proliferation, progesterone biosynthetic process, signal transduction, spermatogenesis, transforming growth factor beta receptor signaling pathway cytoplasm, extracellular region follicle-stimulating hormone activity, hormone activity, protein binding, protein heterodimerization activity Human FSHR GOC UniProtKB {GO:0005515=PMID:15196694, GO:0008406=PMID:9020851, GO:0005886=Reactome:REACT_22268, GO:0009986=GO_REF:0000019, GO:0042699=PMID:9020851, GO:0004963=GO_REF:0000002, GO:0007283=PMID:9020851, GO:0007292=PMID:9020851, GO:0008585=PMID:7553856, GO:0045056=GO_REF:0000019, GO:0007186=PMID:9020851, GO:0016021=GO_REF:0000037, GO:0007189=GO_REF:0000019, GO:0017046=GO_REF:0000019, GO:0035093=GO_REF:0000019, GO:0008584=PMID:17848411, GO:0005768=GO_REF:0000019, GO:0033044=GO_REF:0000019} P23945 Follicle-stimulating hormone receptor protein 20130413 {GO:0005515=IPI, GO:0008406=TAS, GO:0005886=TAS, GO:0009986=IEA, GO:0042699=TAS, GO:0004963=IEA, GO:0007283=TAS, GO:0007292=TAS, GO:0008585=TAS, GO:0045056=IEA, GO:0007186=TAS, GO:0016021=IEA, GO:0007189=IEA, GO:0017046=IEA, GO:0035093=IEA, GO:0008584=IEP, GO:0005768=IEA, GO:0033044=IEA} G-protein coupled receptor signaling pathway, adenylate cyclase-activating G-protein coupled receptor signaling pathway, female gamete generation, female gonad development, follicle-stimulating hormone signaling pathway, gonad development, male gonad development, regulation of chromosome organization, spermatogenesis, spermatogenesis, exchange of chromosomal proteins, transcytosis cell surface, endosome, integral to membrane, plasma membrane follicle-stimulating hormone receptor activity, peptide hormone binding, protein binding Human FSIP1 null null {} null null null null {} null null null FSIP2 UniProtKB UniProtKB {GO:0005739=GO_REF:0000019, GO:0030529=GO_REF:0000038, GO:0003676=GO_REF:0000038} Q8NAU3 Fibrous sheath-interacting protein 2 protein 20130413 {GO:0005739=IEA, GO:0030529=IEA, GO:0003676=IEA} mitochondrion, ribonucleoprotein complex nucleic acid binding Human UniProtKB-KW:KW-0687 FST Reactome UniProtKB {GO:0005515=PMID:16198295, GO:0007389=GO_REF:0000019, GO:0007276=GO_REF:0000019, GO:0046882=GO_REF:0000029, GO:0032926=PMID:11948405, GO:0005576=Reactome:REACT_150395, GO:0005634=GO_REF:0000019, GO:0043395=GO_REF:0000019, GO:0000122=PMID:12702211, GO:0030509=GO_REF:0000019, GO:0043616=GO_REF:0000019, GO:0031069=GO_REF:0000019, GO:0008585=GO_REF:0000019, GO:0051798=PMID:12514121, GO:0005737=GO_REF:0000019, GO:0002244=PMID:15451575, GO:0048185=PMID:12697670, GO:0042475=GO_REF:0000019, GO:0045596=GO_REF:0000019, GO:0004871=PMID:12702211} P19883 Follistatin protein 20120921 {GO:0005515=IPI, GO:0007389=IEA, GO:0007276=IEA, GO:0046882=NAS, GO:0032926=IDA, GO:0005576=TAS, GO:0005634=IEA, GO:0043395=IEA, GO:0000122=IDA, GO:0030509=IEA, GO:0043616=IEA, GO:0031069=IEA, GO:0008585=IEA, GO:0051798=IDA, GO:0005737=IEA, GO:0002244=IDA, GO:0048185=IPI, GO:0042475=IEA, GO:0045596=IEA, GO:0004871=NAS} BMP signaling pathway, female gonad development, gamete generation, hair follicle morphogenesis, hematopoietic progenitor cell differentiation, keratinocyte proliferation, negative regulation of activin receptor signaling pathway, negative regulation of cell differentiation, negative regulation of follicle-stimulating hormone secretion, negative regulation of transcription from RNA polymerase II promoter, odontogenesis of dentin-containing tooth, pattern specification process, positive regulation of hair follicle development cytoplasm, extracellular region, nucleus activin binding, heparan sulfate proteoglycan binding, protein binding, signal transducer activity Human FSTL1 Reactome UniProtKB {GO:0005509=GO_REF:0000002, GO:0005576=Reactome:REACT_12026, GO:0030509=Reactome:REACT_12034, GO:0005615=PMID:9786430, GO:0008201=GO_REF:0000037} Q12841 Follistatin-related protein 1 protein 20130301 {GO:0005509=IEA, GO:0005576=TAS, GO:0030509=TAS, GO:0005615=TAS, GO:0008201=IEA} BMP signaling pathway extracellular region, extracellular space calcium ion binding, heparin binding Human FSTL3 IntAct UniProtKB {GO:0005515=PMID:15574124, GO:0030325=GO_REF:0000019, GO:0030324=GO_REF:0000019, GO:0005634=PMID:16150905, GO:0007283=GO_REF:0000019, GO:0005615=PMID:16150905, GO:0030514=PMID:17878677, GO:0002244=PMID:15451575, GO:0048185=PMID:12697670, GO:0045944=PMID:17868029, GO:0090101=PMID:17878677, GO:0030141=GO_REF:0000019, GO:0001968=PMID:16336961, GO:0044306=GO_REF:0000019, GO:0005794=GO_REF:0000019, GO:0022409=PMID:16336961, GO:0006357=PMID:11948405, GO:0001822=GO_REF:0000019, GO:0032926=PMID:12697670, GO:0045671=PMID:15574124, GO:0005576=Reactome:REACT_150306, GO:0006351=GO_REF:0000037, GO:0071248=GO_REF:0000019, GO:0001503=GO_REF:0000037, GO:0008584=GO_REF:0000019} O95633 Follistatin-related protein 3 protein 20130415 {GO:0005515=IPI, GO:0030325=IEA, GO:0030324=IEA, GO:0005634=IDA, GO:0007283=IEA, GO:0005615=IDA, GO:0030514=IDA, GO:0002244=IDA, GO:0048185=IPI, GO:0045944=IDA, GO:0090101=IDA, GO:0030141=IEA, GO:0001968=IPI, GO:0044306=IEA, GO:0005794=IEA, GO:0022409=IDA, GO:0006357=IDA, GO:0001822=IEA, GO:0032926=IDA, GO:0045671=IDA, GO:0005576=TAS, GO:0006351=IEA, GO:0071248=IEA, GO:0001503=IEA, GO:0008584=IEA} adrenal gland development, cellular response to metal ion, hematopoietic progenitor cell differentiation, kidney development, lung development, male gonad development, negative regulation of BMP signaling pathway, negative regulation of activin receptor signaling pathway, negative regulation of osteoclast differentiation, negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway, ossification, positive regulation of cell-cell adhesion, positive regulation of transcription from RNA polymerase II promoter, regulation of transcription from RNA polymerase II promoter, spermatogenesis, transcription, DNA-dependent Golgi apparatus, extracellular region, extracellular space, neuron projection terminus, nucleus, secretory granule activin binding, fibronectin binding, protein binding Human UniProtKB:O43184-2 FSTL4 UniProtKB UniProtKB {GO:0005509=GO_REF:0000002, GO:0005576=GO_REF:0000039} Q6MZW2 Follistatin-related protein 4 protein 20130413 {GO:0005509=IEA, GO:0005576=IEA} extracellular region calcium ion binding Human UniProtKB-SubCell:SL-0243 FTCD Reactome UniProtKB {GO:0030412=Reactome:REACT_485, GO:0005794=GO_REF:0000039, GO:0019557=GO_REF:0000041, GO:0005814=GO_REF:0000039, GO:0019556=GO_REF:0000041, GO:0006548=Reactome:REACT_1249, GO:0044281=Reactome:REACT_111217, GO:0003824=GO_REF:0000002, GO:0030409=GO_REF:0000003, GO:0005829=Reactome:REACT_485, GO:0035999=GO_REF:0000041, GO:0034641=Reactome:REACT_13, GO:0005542=GO_REF:0000037, GO:0005737=PMID:10029623, GO:0006760=PMID:10029623, GO:0007010=GO_REF:0000019, GO:0016740=GO_REF:0000002, GO:0044237=GO_REF:0000002} O95954 Formimidoyltransferase-cyclodeaminase protein 20130213 {GO:0030412=EXP, GO:0005794=IEA, GO:0019557=IEA, GO:0005814=IEA, GO:0019556=IEA, GO:0006548=TAS, GO:0044281=TAS, GO:0003824=IEA, GO:0030409=IEA, GO:0005829=TAS, GO:0035999=IEA, GO:0034641=TAS, GO:0005542=IEA, GO:0005737=TAS, GO:0006760=TAS, GO:0007010=IEA, GO:0016740=IEA, GO:0044237=IEA} cellular metabolic process, cellular nitrogen compound metabolic process, cytoskeleton organization, folic acid-containing compound metabolic process, histidine catabolic process, histidine catabolic process to glutamate and formamide, histidine catabolic process to glutamate and formate, small molecule metabolic process, tetrahydrofolate interconversion Golgi apparatus, centriole, cytoplasm, cytosol catalytic activity, folic acid binding, formimidoyltetrahydrofolate cyclodeaminase activity, glutamate formimidoyltransferase activity, transferase activity Human FTH1 IntAct UniProtKB {GO:0005515=PMID:21988832, GO:0008285=GO_REF:0000024, GO:0005506=PMID:3020541, GO:0006892=Reactome:REACT_11235, GO:0048147=PMID:9924025, GO:0006880=PMID:9924025, GO:0055085=Reactome:REACT_15518, GO:0008199=GO_REF:0000002, GO:0005829=Reactome:REACT_115629, GO:0006879=Reactome:REACT_25060, GO:0005739=GO_REF:0000019, GO:0008043=PMID:6589621, GO:0004322=GO_REF:0000003, GO:0006955=GO_REF:0000024, GO:0016491=GO_REF:0000002, GO:0006826=GO_REF:0000002, GO:0016044=Reactome:REACT_11123} P02794 Ferritin heavy chain protein 20130415 {GO:0005515=IPI, GO:0008285=ISS, GO:0005506=TAS, GO:0006892=TAS, GO:0048147=IDA, GO:0006880=IDA, GO:0055085=TAS, GO:0008199=IEA, GO:0005829=TAS, GO:0006879=TAS, GO:0005739=IEA, GO:0008043=TAS, GO:0004322=IEA, GO:0006955=ISS, GO:0016491=IEA, GO:0006826=IEA, GO:0016044=TAS} cellular iron ion homeostasis, cellular membrane organization, immune response, intracellular sequestering of iron ion, iron ion transport, negative regulation of cell proliferation, negative regulation of fibroblast proliferation, post-Golgi vesicle-mediated transport, transmembrane transport cytosol, intracellular ferritin complex, mitochondrion ferric iron binding, ferroxidase activity, iron ion binding, oxidoreductase activity, protein binding Human UniProtKB:Q9UER7 FTL IntAct UniProtKB {GO:0005515=PMID:23275563, GO:0008219=GO_REF:0000037, GO:0005506=PMID:19923220, GO:0006892=Reactome:REACT_11235, GO:0055072=PMID:19923220, GO:0055085=Reactome:REACT_15518, GO:0042802=PMID:16790936, GO:0008199=GO_REF:0000002, GO:0005829=Reactome:REACT_115629, GO:0008043=PMID:20159981, GO:0006879=Reactome:REACT_25060, GO:0016491=GO_REF:0000002, GO:0006826=GO_REF:0000002, GO:0016044=Reactome:REACT_11123} P02792 Ferritin light chain protein 20130415 {GO:0005515=IPI, GO:0008219=IEA, GO:0005506=IDA, GO:0006892=TAS, GO:0055072=TAS, GO:0055085=TAS, GO:0042802=IPI, GO:0008199=IEA, GO:0005829=TAS, GO:0008043=IDA, GO:0006879=TAS, GO:0016491=IEA, GO:0006826=IEA, GO:0016044=TAS} cell death, cellular iron ion homeostasis, cellular membrane organization, iron ion homeostasis, iron ion transport, post-Golgi vesicle-mediated transport, transmembrane transport cytosol, intracellular ferritin complex ferric iron binding, identical protein binding, iron ion binding, oxidoreductase activity, protein binding Human UniProtKB:P02792 FTO BHF-UCL UniProtKB {GO:0001659=GO_REF:0000019, GO:0070989=PMID:18775698, GO:0043734=PMID:20376003, GO:0005634=PMID:17991826, GO:0010883=GO_REF:0000019, GO:0042245=PMID:18775698, GO:0035515=PMID:18775698, GO:0008198=PMID:20376003, GO:0035553=PMID:18775698, GO:0035516=PMID:18775698, GO:0035552=PMID:18775698, GO:0006307=PMID:18775698, GO:0040014=GO_REF:0000019, GO:0080111=PMID:18775698, GO:0070350=GO_REF:0000019, GO:0044065=GO_REF:0000019, GO:0016702=GO_REF:0000037, GO:0060612=GO_REF:0000019} Q9C0B1 Alpha-ketoglutarate-dependent dioxygenase FTO protein 20100517 {GO:0001659=IEA, GO:0070989=IDA, GO:0043734=IDA, GO:0005634=ISS, GO:0010883=IEA, GO:0042245=IDA, GO:0035515=IDA, GO:0008198=IDA, GO:0035553=IDA, GO:0035516=IDA, GO:0035552=IDA, GO:0006307=IDA, GO:0040014=IEA, GO:0080111=IDA, GO:0070350=IEA, GO:0044065=IEA, GO:0016702=IEA, GO:0060612=IEA} DNA dealkylation involved in DNA repair, DNA demethylation, RNA repair, adipose tissue development, oxidative demethylation, oxidative single-stranded DNA demethylation, oxidative single-stranded RNA demethylation, regulation of lipid storage, regulation of multicellular organism growth, regulation of respiratory system process, regulation of white fat cell proliferation, temperature homeostasis nucleus DNA-N1-methyladenine dioxygenase activity, ferrous iron binding, oxidative DNA demethylase activity, oxidative RNA demethylase activity, oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen Human FTSJ1 UniProtKB UniProtKB {GO:0005737=GO_REF:0000039, GO:0001510=GO_REF:0000002, GO:0008168=GO_REF:0000037, GO:0008033=GO_REF:0000037} Q9UET6 Putative tRNA (cytidine(32)/guanosine(34)-2'-O)-methyltransferase protein 20130413 {GO:0005737=IEA, GO:0001510=IEA, GO:0008168=IEA, GO:0008033=IEA} RNA methylation, tRNA processing cytoplasm methyltransferase activity Human UniProtKB-SubCell:SL-0086 FTSJ2 BHF-UCL UniProtKB {GO:0005739=GO_REF:0000024, GO:0031167=PMID:11827451, GO:0001510=GO_REF:0000002, GO:0008283=PMID:11827451, GO:0006364=PMID:11827451, GO:0008650=PMID:11827451, GO:0008168=GO_REF:0000002, GO:0005730=PMID:11827451} Q9UI43 Putative ribosomal RNA methyltransferase 2 protein 20110310 {GO:0005739=ISS, GO:0031167=NAS, GO:0001510=IEA, GO:0008283=NAS, GO:0006364=NAS, GO:0008650=NAS, GO:0008168=IEA, GO:0005730=IDA} RNA methylation, cell proliferation, rRNA methylation, rRNA processing mitochondrion, nucleolus methyltransferase activity, rRNA (uridine-2'-O-)-methyltransferase activity Human UniProtKB:Q9CPY0 FTSJ3 IntAct UniProtKB {GO:0005515=PMID:21903422, GO:0001510=GO_REF:0000002, GO:0006364=GO_REF:0000037, GO:0008168=GO_REF:0000037, GO:0005730=GO_REF:0000039} Q8IY81 pre-rRNA processing protein FTSJ3 protein 20130415 {GO:0005515=IPI, GO:0001510=IEA, GO:0006364=IEA, GO:0008168=IEA, GO:0005730=IEA} RNA methylation, rRNA processing nucleolus methyltransferase activity, protein binding Human UniProtKB:Q9Y6K5 FTSJD1 UniProtKB UniProtKB {GO:0008168=GO_REF:0000037, GO:0016021=GO_REF:0000037} Q8IYT2 FtsJ methyltransferase domain-containing protein 1 protein 20130413 {GO:0008168=IEA, GO:0016021=IEA} integral to membrane methyltransferase activity Human UniProtKB-KW:KW-0812 FTSJD2 HPA UniProtKB {GO:0005737=GO_REF:0000052, GO:0004483=PMID:20713356, GO:0008168=GO_REF:0000002, GO:0005730=GO_REF:0000052, GO:0006370=PMID:20713356, GO:0080009=PMID:20713356, GO:0005634=GO_REF:0000052, GO:0003676=GO_REF:0000002} Q8N1G2 Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 1 protein 20101115 {GO:0005737=IDA, GO:0004483=IDA, GO:0008168=IEA, GO:0005730=IDA, GO:0006370=IMP, GO:0080009=IDA, GO:0005634=IDA, GO:0003676=IEA} 7-methylguanosine mRNA capping, mRNA methylation cytoplasm, nucleolus, nucleus mRNA (nucleoside-2'-O-)-methyltransferase activity, methyltransferase activity, nucleic acid binding Human FUBP1 HPA UniProtKB {GO:0003700=PMID:8125259, GO:0006366=PMID:8125259, GO:0003697=PMID:8125259, GO:0003723=GO_REF:0000002, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052} Q96AE4 Far upstream element-binding protein 1 protein 20080205 {GO:0003700=TAS, GO:0006366=TAS, GO:0003697=TAS, GO:0003723=IEA, GO:0005730=IDA, GO:0005634=IDA} transcription from RNA polymerase II promoter nucleolus, nucleus RNA binding, sequence-specific DNA binding transcription factor activity, single-stranded DNA binding NOT Human FUBP3 UniProtKB UniProtKB {GO:0005737=PMID:19087307, GO:0003723=GO_REF:0000002, GO:0005634=PMID:8940189, GO:0045893=PMID:8940189, GO:0003677=GO_REF:0000037, GO:0006351=PMID:8940189} Q96I24 Far upstream element-binding protein 3 protein 20111118 {GO:0005737=IDA, GO:0003723=IEA, GO:0005634=NAS, GO:0045893=IDA, GO:0003677=IEA, GO:0006351=IDA} positive regulation of transcription, DNA-dependent, transcription, DNA-dependent cytoplasm, nucleus DNA binding, RNA binding Human FUCA1 UniProtKB UniProtKB {GO:0005737=PMID:11698403, GO:0004560=PMID:11698403, GO:0006027=PMID:11698403, GO:0030246=GO_REF:0000019, GO:0006004=GO_REF:0000002, GO:0005764=GO_REF:0000039} P04066 Tissue alpha-L-fucosidase protein 20031216 {GO:0005737=IC, GO:0004560=TAS, GO:0006027=NAS, GO:0030246=IEA, GO:0006004=IEA, GO:0005764=IEA} fucose metabolic process, glycosaminoglycan catabolic process cytoplasm, lysosome alpha-L-fucosidase activity, carbohydrate binding Human FUCA2 UniProtKB UniProtKB {GO:0005975=GO_REF:0000002, GO:0004560=GO_REF:0000003, GO:0005576=GO_REF:0000039, GO:0006004=GO_REF:0000002} Q9BTY2 Plasma alpha-L-fucosidase protein 20130413 {GO:0005975=IEA, GO:0004560=IEA, GO:0005576=IEA, GO:0006004=IEA} carbohydrate metabolic process, fucose metabolic process extracellular region alpha-L-fucosidase activity Human UniProtKB-SubCell:SL-0243 FUK UniProtKB UniProtKB {GO:0005737=GO_REF:0000002, GO:0050201=PMID:12056818, GO:0016301=GO_REF:0000038, GO:0016773=GO_REF:0000002, GO:0005524=GO_REF:0000037, GO:0016772=GO_REF:0000002} Q8N0W3 L-fucose kinase protein 20041109 {GO:0005737=IEA, GO:0050201=NAS, GO:0016301=IEA, GO:0016773=IEA, GO:0005524=IEA, GO:0016772=IEA} cytoplasm ATP binding, fucokinase activity, kinase activity, phosphotransferase activity, alcohol group as acceptor, transferase activity, transferring phosphorus-containing groups Human FUNDC1 MGI UniProtKB {GO:0005515=PMID:22267086, GO:0001666=PMID:22267086, GO:0000422=PMID:22267086, GO:0005741=PMID:22267086, GO:0031307=PMID:22267086} Q8IVP5 FUN14 domain-containing protein 1 protein 20120727 {GO:0005515=IPI, GO:0001666=IMP, GO:0000422=IMP, GO:0005741=IDA, GO:0031307=IDA} mitochondrion degradation, response to hypoxia integral to mitochondrial outer membrane, mitochondrial outer membrane protein binding Human FUNDC2 LIFEdb UniProtKB {GO:0005739=GO_REF:0000054} Q9BWH2 FUN14 domain-containing protein 2 protein 20100607 {GO:0005739=IDA} mitochondrion Human FURIN BHF-UCL UniProtKB {GO:0005802=PMID:14744861, GO:0032455=Reactome:REACT_11062, GO:0051044=PMID:17010968, GO:0005886=Reactome:REACT_150355, GO:0004252=PMID:10567353, GO:0004867=PMID:10567353, GO:0008283=PMID:15899807, GO:0002020=PMID:14744861, GO:0032911=PMID:15899807, GO:0005615=PMID:10567353, GO:0052548=PMID:14744861, GO:0046872=GO_REF:0000037, GO:0016486=PMID:9242664, GO:0007219=Reactome:REACT_299, GO:0022617=Reactome:REACT_118572, GO:0016485=PMID:14744861, GO:0030198=Reactome:REACT_118779, GO:0030574=Reactome:REACT_150401, GO:0006508=Reactome:REACT_733, GO:0007179=Reactome:REACT_120850, GO:0030140=PMID:15078902, GO:0042277=PMID:8940009, GO:0048011=Reactome:REACT_11061, GO:0009986=PMID:16537537, GO:0042176=PMID:15899807, GO:0019067=PMID:8940009, GO:0048406=PMID:8615794, GO:0005796=Reactome:REACT_10058, GO:0043043=PMID:8262946, GO:0032902=PMID:8615794, GO:0009966=GO_REF:0000019, GO:0032904=PMID:10567353, GO:0017187=Reactome:REACT_1132, GO:0004175=PMID:9242664, GO:0000139=Reactome:REACT_118833, GO:0032804=PMID:16912035, GO:0008233=PMID:15082773, GO:0045121=PMID:17010968, GO:0016021=GO_REF:0000037, GO:0032940=PMID:8615794, GO:0044267=Reactome:REACT_17015, GO:0006465=PMID:16912035, GO:0043687=Reactome:REACT_22161} P09958 Furin protein 20080415 {GO:0005802=IDA, GO:0032455=TAS, GO:0051044=IC, GO:0005886=TAS, GO:0004252=IDA, GO:0004867=IDA, GO:0008283=IMP, GO:0002020=IPI, GO:0032911=IMP, GO:0005615=IDA, GO:0052548=IDA, GO:0046872=IEA, GO:0016486=IDA, GO:0007219=TAS, GO:0022617=TAS, GO:0016485=IDA, GO:0030198=TAS, GO:0030574=TAS, GO:0006508=TAS, GO:0007179=TAS, GO:0030140=IDA, GO:0042277=IDA, GO:0048011=TAS, GO:0009986=IDA, GO:0042176=IMP, GO:0019067=IEP, GO:0048406=IDA, GO:0005796=TAS, GO:0043043=IDA, GO:0032902=IDA, GO:0009966=IEA, GO:0032904=IDA, GO:0017187=TAS, GO:0004175=IDA, GO:0000139=TAS, GO:0032804=IDA, GO:0008233=IDA, GO:0045121=IDA, GO:0016021=IEA, GO:0032940=IDA, GO:0044267=TAS, GO:0006465=IDA, GO:0043687=TAS} Notch signaling pathway, cell proliferation, cellular protein metabolic process, collagen catabolic process, extracellular matrix disassembly, extracellular matrix organization, negative regulation of low-density lipoprotein particle receptor catabolic process, negative regulation of nerve growth factor production, negative regulation of transforming growth factor beta1 production, nerve growth factor processing, nerve growth factor production, neurotrophin TRK receptor signaling pathway, peptide biosynthetic process, peptide hormone processing, peptidyl-glutamic acid carboxylation, positive regulation of membrane protein ectodomain proteolysis, post-translational protein modification, protein processing, proteolysis, regulation of endopeptidase activity, regulation of protein catabolic process, regulation of signal transduction, secretion by cell, signal peptide processing, transforming growth factor beta receptor signaling pathway, viral assembly, maturation, egress, and release Golgi lumen, Golgi membrane, cell surface, extracellular space, integral to membrane, membrane raft, plasma membrane, trans-Golgi network, trans-Golgi network transport vesicle endopeptidase activity, metal ion binding, nerve growth factor binding, peptidase activity, peptide binding, protease binding, serine-type endopeptidase activity, serine-type endopeptidase inhibitor activity Human FUS HPA UniProtKB {GO:0005515=PMID:20085233, GO:0008380=Reactome:REACT_1735, GO:0010467=Reactome:REACT_71, GO:0008219=GO_REF:0000037, GO:0003723=GO_REF:0000037, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0003676=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0005622=GO_REF:0000002, GO:0005737=GO_REF:0000019, GO:0000166=GO_REF:0000002, GO:0000398=Reactome:REACT_467, GO:0008270=GO_REF:0000002, GO:0005654=Reactome:REACT_1935} P35637 RNA-binding protein FUS protein 20080205 {GO:0005515=IPI, GO:0008380=TAS, GO:0010467=TAS, GO:0008219=IEA, GO:0003723=IEA, GO:0005730=IDA, GO:0005634=IDA, GO:0003676=IEA, GO:0003677=IEA, GO:0005622=IEA, GO:0005737=IEA, GO:0000166=IEA, GO:0000398=TAS, GO:0008270=IEA, GO:0005654=TAS} RNA splicing, cell death, gene expression, mRNA splicing, via spliceosome cytoplasm, intracellular, nucleolus, nucleoplasm, nucleus DNA binding, RNA binding, nucleic acid binding, nucleotide binding, protein binding, zinc ion binding NOT Human FUT1 PINC UniProtKB {GO:0042355=PMID:11698403, GO:0005794=PMID:11698403, GO:0016020=PMID:2118655, GO:0005975=PMID:2118655, GO:0005887=PMID:2118655, GO:0008417=PMID:2118655, GO:0008107=PMID:11698403, GO:0032580=GO_REF:0000039, GO:0006486=PMID:11698403} P19526 Galactoside 2-alpha-L-fucosyltransferase 1 protein 20030904 {GO:0042355=NAS, GO:0005794=TAS, GO:0016020=TAS, GO:0005975=TAS, GO:0005887=TAS, GO:0008417=TAS, GO:0008107=TAS, GO:0032580=IEA, GO:0006486=TAS} L-fucose catabolic process, carbohydrate metabolic process, protein glycosylation Golgi apparatus, Golgi cisterna membrane, integral to plasma membrane, membrane fucosyltransferase activity, galactoside 2-alpha-L-fucosyltransferase activity Human FUT10 UniProtKB UniProtKB {GO:0030097=PMID:11698403, GO:0046920=PMID:11698403, GO:0042355=PMID:11698403, GO:0005794=PMID:11698403, GO:0009790=PMID:11698403, GO:0006605=PMID:11698403, GO:0007399=PMID:11698403, GO:0009566=PMID:11698403, GO:0006457=PMID:11698403, GO:0032580=GO_REF:0000039, GO:0042060=PMID:11698403, GO:0006486=PMID:11698403, GO:0016021=GO_REF:0000037} Q6P4F1 Alpha-(1,3)-fucosyltransferase 10 protein 20070906 {GO:0030097=NAS, GO:0046920=TAS, GO:0042355=NAS, GO:0005794=TAS, GO:0009790=NAS, GO:0006605=NAS, GO:0007399=NAS, GO:0009566=NAS, GO:0006457=NAS, GO:0032580=IEA, GO:0042060=NAS, GO:0006486=TAS, GO:0016021=IEA} L-fucose catabolic process, embryo development, fertilization, hemopoiesis, nervous system development, protein folding, protein glycosylation, protein targeting, wound healing Golgi apparatus, Golgi cisterna membrane, integral to membrane alpha-(1->3)-fucosyltransferase activity Human FUT11 UniPathway UniProtKB {GO:0046920=GO_REF:0000002, GO:0032580=GO_REF:0000039, GO:0006486=GO_REF:0000041, GO:0016021=GO_REF:0000037} Q495W5 Alpha-(1,3)-fucosyltransferase 11 protein 20130413 {GO:0046920=IEA, GO:0032580=IEA, GO:0006486=IEA, GO:0016021=IEA} protein glycosylation Golgi cisterna membrane, integral to membrane alpha-(1->3)-fucosyltransferase activity Human UniPathway:UPA00378 FUT4 GOC UniProtKB {GO:0042355=PMID:11698403, GO:0046920=PMID:11698403, GO:0005794=PMID:11698403, GO:0016020=PMID:1716630, GO:0009986=GO_REF:0000019, GO:0005975=PMID:1716630, GO:0008417=PMID:1716630, GO:0032580=GO_REF:0000039, GO:0006486=PMID:11698403, GO:0016021=GO_REF:0000037, GO:0036065=PMID:1716630, GO:0071944=GO_REF:0000019} P22083 Alpha-(1,3)-fucosyltransferase protein 20130413 {GO:0042355=NAS, GO:0046920=TAS, GO:0005794=TAS, GO:0016020=TAS, GO:0009986=IEA, GO:0005975=TAS, GO:0008417=TAS, GO:0032580=IEA, GO:0006486=TAS, GO:0016021=IEA, GO:0036065=TAS, GO:0071944=IEA} L-fucose catabolic process, carbohydrate metabolic process, fucosylation, protein glycosylation Golgi apparatus, Golgi cisterna membrane, cell periphery, cell surface, integral to membrane, membrane alpha-(1->3)-fucosyltransferase activity, fucosyltransferase activity Human FUT7 GOC UniProtKB {GO:0042355=PMID:11698403, GO:0046920=PMID:11698403, GO:0005794=PMID:11698403, GO:0008417=PMID:8207002, GO:0032580=GO_REF:0000039, GO:0002522=GO_REF:0000019, GO:0002361=GO_REF:0000019, GO:0006486=PMID:11698403, GO:0016021=GO_REF:0000037, GO:0036065=PMID:8207002} Q11130 Alpha-(1,3)-fucosyltransferase protein 20130413 {GO:0042355=NAS, GO:0046920=TAS, GO:0005794=TAS, GO:0008417=TAS, GO:0032580=IEA, GO:0002522=IEA, GO:0002361=IEA, GO:0006486=TAS, GO:0016021=IEA, GO:0036065=TAS} CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation, L-fucose catabolic process, fucosylation, leukocyte migration involved in immune response, protein glycosylation Golgi apparatus, Golgi cisterna membrane, integral to membrane alpha-(1->3)-fucosyltransferase activity, fucosyltransferase activity Human FUT8 GOC UniProtKB {GO:0036071=PMID:9133635, GO:0042355=PMID:11698403, GO:0009312=PMID:9133635, GO:0017124=GO_REF:0000037, GO:0005794=PMID:11698403, GO:0007585=GO_REF:0000019, GO:0016757=GO_REF:0000038, GO:0046921=GO_REF:0000019, GO:0033578=GO_REF:0000002, GO:0001701=PMID:11698403, GO:0000139=Reactome:REACT_25399, GO:0016477=GO_REF:0000019, GO:0007229=GO_REF:0000019, GO:0006491=PMID:11698403, GO:0032580=GO_REF:0000039, GO:0007179=GO_REF:0000019, GO:0043112=GO_REF:0000019, GO:0006487=PMID:9133635, GO:0016021=GO_REF:0000037, GO:0008424=PMID:11698403, GO:0044267=Reactome:REACT_17015, GO:0043687=Reactome:REACT_22161, GO:0018279=Reactome:REACT_22426} Q9BYC5 Alpha-(1,6)-fucosyltransferase protein 20130413 {GO:0036071=TAS, GO:0042355=NAS, GO:0009312=TAS, GO:0017124=IEA, GO:0005794=NAS, GO:0007585=IEA, GO:0016757=IEA, GO:0046921=IEA, GO:0033578=IEA, GO:0001701=NAS, GO:0000139=TAS, GO:0016477=IEA, GO:0007229=IEA, GO:0006491=TAS, GO:0032580=IEA, GO:0007179=IEA, GO:0043112=IEA, GO:0006487=TAS, GO:0016021=IEA, GO:0008424=TAS, GO:0044267=TAS, GO:0043687=TAS, GO:0018279=TAS} L-fucose catabolic process, N-glycan fucosylation, N-glycan processing, cell migration, cellular protein metabolic process, in utero embryonic development, integrin-mediated signaling pathway, oligosaccharide biosynthetic process, post-translational protein modification, protein N-linked glycosylation, protein N-linked glycosylation via asparagine, protein glycosylation in Golgi, receptor metabolic process, respiratory gaseous exchange, transforming growth factor beta receptor signaling pathway Golgi apparatus, Golgi cisterna membrane, Golgi membrane, integral to membrane SH3 domain binding, alpha-(1->6)-fucosyltransferase activity, glycoprotein 6-alpha-L-fucosyltransferase activity, transferase activity, transferring glycosyl groups Human FUT9 GOC UniProtKB {GO:0042355=PMID:11698403, GO:0046920=PMID:11698403, GO:0005794=PMID:11698403, GO:0005975=PMID:10386598, GO:0008417=PMID:10386598, GO:0032580=GO_REF:0000039, GO:0006486=PMID:11698403, GO:0016021=GO_REF:0000037, GO:0036065=PMID:10386598, GO:0007399=GO_REF:0000019} Q9Y231 Alpha-(1,3)-fucosyltransferase protein 20130413 {GO:0042355=NAS, GO:0046920=TAS, GO:0005794=TAS, GO:0005975=TAS, GO:0008417=TAS, GO:0032580=IEA, GO:0006486=TAS, GO:0016021=IEA, GO:0036065=TAS, GO:0007399=IEA} L-fucose catabolic process, carbohydrate metabolic process, fucosylation, nervous system development, protein glycosylation Golgi apparatus, Golgi cisterna membrane, integral to membrane alpha-(1->3)-fucosyltransferase activity, fucosyltransferase activity Human FUZ UniProtKB UniProtKB {GO:0001736=GO_REF:0000024, GO:0042384=GO_REF:0000024, GO:0010172=GO_REF:0000024, GO:0005737=GO_REF:0000039, GO:0008589=GO_REF:0000024, GO:0001843=GO_REF:0000024, GO:0048704=GO_REF:0000024, GO:0005856=GO_REF:0000039, GO:0015031=GO_REF:0000037, GO:0001942=GO_REF:0000024} Q9BT04 Protein fuzzy homolog protein 20110413 {GO:0001736=ISS, GO:0042384=ISS, GO:0010172=ISS, GO:0005737=IEA, GO:0008589=ISS, GO:0001843=ISS, GO:0048704=ISS, GO:0005856=IEA, GO:0015031=IEA, GO:0001942=ISS} cilium assembly, embryonic body morphogenesis, embryonic skeletal system morphogenesis, establishment of planar polarity, hair follicle development, neural tube closure, protein transport, regulation of smoothened signaling pathway cytoplasm, cytoskeleton Human UniProtKB:Q3UYI6 FXN BHF-UCL UniProtKB {GO:0005515=PMID:15123683, GO:0014070=GO_REF:0000019, GO:0008284=PMID:18160053, GO:0016540=PMID:12785837, GO:0051353=PMID:18160053, GO:0070301=PMID:15641778, GO:0016226=GO_REF:0000002, GO:0030307=PMID:15509595, GO:0045773=GO_REF:0000019, GO:0044281=Reactome:REACT_111217, GO:0009792=GO_REF:0000019, GO:0005829=PMID:17468497, GO:0006119=GO_REF:0000019, GO:0005739=PMID:17468497, GO:0009060=GO_REF:0000019, GO:0006879=PMID:18160053, GO:0040015=GO_REF:0000019, GO:0090201=PMID:16608849, GO:0005759=GO_REF:0000024, GO:0010039=PMID:18424449, GO:0007628=GO_REF:0000019, GO:0006811=GO_REF:0000037, GO:0046621=GO_REF:0000019, GO:0010722=PMID:15123683, GO:0034986=PMID:15123683, GO:0043066=PMID:16608849, GO:0019230=GO_REF:0000019, GO:0051536=PMID:17285345, GO:0051537=PMID:12785837, GO:0042493=GO_REF:0000019, GO:0051349=PMID:18160053, GO:0051347=PMID:18160053, GO:0008198=PMID:15123683, GO:0006783=PMID:15123683, GO:0008199=PMID:18537827, GO:0004322=PMID:15641778, GO:0048554=PMID:15509595, GO:0007005=GO_REF:0000019, GO:0019899=GO_REF:0000019, GO:0018283=PMID:12785837} Q16595 Frataxin, mitochondrial protein 20080912 {GO:0005515=IPI, GO:0014070=IEA, GO:0008284=IMP, GO:0016540=IDA, GO:0051353=IMP, GO:0070301=IDA, GO:0016226=IEA, GO:0030307=IMP, GO:0045773=IEA, GO:0044281=TAS, GO:0009792=IEA, GO:0005829=IDA, GO:0006119=IEA, GO:0005739=IDA, GO:0009060=IEA, GO:0006879=IMP, GO:0040015=IEA, GO:0090201=IMP, GO:0005759=ISS, GO:0010039=IMP, GO:0007628=IEA, GO:0006811=IEA, GO:0046621=IEA, GO:0010722=IDA, GO:0034986=IDA, GO:0043066=IMP, GO:0019230=IEA, GO:0051536=IDA, GO:0051537=IDA, GO:0042493=IEA, GO:0051349=IMP, GO:0051347=IMP, GO:0008198=IDA, GO:0006783=NAS, GO:0008199=IDA, GO:0004322=IDA, GO:0048554=IMP, GO:0007005=IEA, GO:0019899=IEA, GO:0018283=IDA} adult walking behavior, aerobic respiration, cellular iron ion homeostasis, cellular response to hydrogen peroxide, embryo development ending in birth or egg hatching, heme biosynthetic process, ion transport, iron incorporation into metallo-sulfur cluster, iron-sulfur cluster assembly, mitochondrion organization, negative regulation of apoptotic process, negative regulation of multicellular organism growth, negative regulation of organ growth, negative regulation of release of cytochrome c from mitochondria, oxidative phosphorylation, positive regulation of axon extension, positive regulation of cell growth, positive regulation of cell proliferation, positive regulation of lyase activity, positive regulation of metalloenzyme activity, positive regulation of oxidoreductase activity, positive regulation of transferase activity, proprioception, protein autoprocessing, regulation of ferrochelatase activity, response to drug, response to iron ion, response to organic cyclic compound, small molecule metabolic process cytosol, mitochondrial matrix, mitochondrion 2 iron, 2 sulfur cluster binding, enzyme binding, ferric iron binding, ferrous iron binding, ferroxidase activity, iron chaperone activity, iron-sulfur cluster binding, protein binding Human FXR1 HPA UniProtKB {GO:0017148=GO_REF:0000019, GO:0005737=GO_REF:0000052, GO:0007517=GO_REF:0000037, GO:0002151=GO_REF:0000019, GO:0003723=PMID:7781595, GO:0005730=PMID:10888599, GO:0043034=GO_REF:0000019, GO:0006915=PMID:9642279, GO:0005634=GO_REF:0000019, GO:0003730=GO_REF:0000019, GO:0005844=GO_REF:0000019, GO:0030154=GO_REF:0000037} P51114 Fragile X mental retardation syndrome-related protein 1 protein 20090616 {GO:0017148=IEA, GO:0005737=IDA, GO:0007517=IEA, GO:0002151=IEA, GO:0003723=TAS, GO:0005730=TAS, GO:0043034=IEA, GO:0006915=TAS, GO:0005634=IEA, GO:0003730=IEA, GO:0005844=IEA, GO:0030154=IEA} apoptotic process, cell differentiation, muscle organ development, negative regulation of translation costamere, cytoplasm, nucleolus, nucleus, polysome G-quadruplex RNA binding, RNA binding, mRNA 3'-UTR binding Human FXR2 HPA UniProtKB {GO:0005515=PMID:19060904, GO:0005737=GO_REF:0000052, GO:0003723=GO_REF:0000037, GO:0022625=PMID:9259278} P51116 Fragile X mental retardation syndrome-related protein 2 protein 20100326 {GO:0005515=IPI, GO:0005737=IDA, GO:0003723=IEA, GO:0022625=TAS} cytoplasm, cytosolic large ribosomal subunit RNA binding, protein binding Human FXYD1 Reactome UniProtKB {GO:0006821=PMID:9169143, GO:0034220=Reactome:REACT_25300, GO:0006936=PMID:9169143, GO:0005886=Reactome:REACT_25287, GO:0016020=GO_REF:0000002, GO:0005887=PMID:9169143, GO:0034707=GO_REF:0000037, GO:0055085=Reactome:REACT_15518, GO:0005254=GO_REF:0000037, GO:0005216=GO_REF:0000002} O00168 Phospholemman protein 20130301 {GO:0006821=TAS, GO:0034220=TAS, GO:0006936=TAS, GO:0005886=TAS, GO:0016020=IEA, GO:0005887=TAS, GO:0034707=IEA, GO:0055085=TAS, GO:0005254=IEA, GO:0005216=IEA} chloride transport, ion transmembrane transport, muscle contraction, transmembrane transport chloride channel complex, integral to plasma membrane, membrane, plasma membrane chloride channel activity, ion channel activity Human FXYD2 Reactome UniProtKB {GO:0005215=PMID:9048881, GO:0005886=Reactome:REACT_25287, GO:0005890=GO_REF:0000029, GO:0001558=GO_REF:0000019, GO:0055085=Reactome:REACT_15518, GO:0043231=GO_REF:0000019, GO:0016323=GO_REF:0000019, GO:0034220=Reactome:REACT_25300, GO:0042127=GO_REF:0000019, GO:0006810=PMID:9048881, GO:0005216=GO_REF:0000029, GO:0005391=GO_REF:0000019, GO:0006811=GO_REF:0000029} P54710 Sodium/potassium-transporting ATPase subunit gamma protein 20130301 {GO:0005215=TAS, GO:0005886=TAS, GO:0005890=NAS, GO:0001558=IEA, GO:0055085=TAS, GO:0043231=IEA, GO:0016323=IEA, GO:0034220=TAS, GO:0042127=IEA, GO:0006810=TAS, GO:0005216=NAS, GO:0005391=IEA, GO:0006811=NAS} ion transmembrane transport, ion transport, regulation of cell growth, regulation of cell proliferation, transmembrane transport, transport basolateral plasma membrane, intracellular membrane-bounded organelle, plasma membrane, sodium:potassium-exchanging ATPase complex ion channel activity, sodium:potassium-exchanging ATPase activity, transporter activity Human FXYD3 Reactome UniProtKB {GO:0006821=PMID:7836447, GO:0034220=Reactome:REACT_25300, GO:0005886=Reactome:REACT_25287, GO:0016020=GO_REF:0000002, GO:0005887=PMID:7836447, GO:0034707=GO_REF:0000037, GO:0055085=Reactome:REACT_15518, GO:0005254=GO_REF:0000037, GO:0005216=GO_REF:0000002} Q14802 FXYD domain-containing ion transport regulator 3 protein 20130301 {GO:0006821=TAS, GO:0034220=TAS, GO:0005886=TAS, GO:0016020=IEA, GO:0005887=TAS, GO:0034707=IEA, GO:0055085=TAS, GO:0005254=IEA, GO:0005216=IEA} chloride transport, ion transmembrane transport, transmembrane transport chloride channel complex, integral to plasma membrane, membrane, plasma membrane chloride channel activity, ion channel activity Human FXYD5 UniProtKB UniProtKB {GO:0045296=PMID:11756660, GO:0016020=GO_REF:0000002, GO:0030033=PMID:11756660, GO:0003779=PMID:11756660, GO:0046588=PMID:11756660, GO:0016021=PMID:11756660, GO:0005216=GO_REF:0000002} Q96DB9 FXYD domain-containing ion transport regulator 5 protein 20021029 {GO:0045296=IDA, GO:0016020=IEA, GO:0030033=NAS, GO:0003779=IDA, GO:0046588=NAS, GO:0016021=IDA, GO:0005216=IEA} microvillus assembly, negative regulation of calcium-dependent cell-cell adhesion integral to membrane, membrane actin binding, cadherin binding, ion channel activity Human FXYD6 LIFEdb UniProtKB {GO:0003674=GO_REF:0000015, GO:0008150=GO_REF:0000015, GO:0034220=Reactome:REACT_25300, GO:0005886=GO_REF:0000054, GO:0016020=GO_REF:0000002, GO:0016021=GO_REF:0000037, GO:0055085=Reactome:REACT_15518, GO:0005216=GO_REF:0000002} Q9H0Q3 FXYD domain-containing ion transport regulator 6 protein 20100607 {GO:0003674=ND, GO:0008150=ND, GO:0034220=TAS, GO:0005886=IDA, GO:0016020=IEA, GO:0016021=IEA, GO:0055085=TAS, GO:0005216=IEA} biological_process, ion transmembrane transport, transmembrane transport integral to membrane, membrane, plasma membrane ion channel activity, molecular_function Human FXYD7 Reactome UniProtKB {GO:0034220=Reactome:REACT_25300, GO:0005886=Reactome:REACT_25287, GO:0016020=GO_REF:0000002, GO:0051117=GO_REF:0000019, GO:0016021=GO_REF:0000037, GO:0055085=Reactome:REACT_15518, GO:0005216=GO_REF:0000002, GO:0043269=GO_REF:0000019} P58549 FXYD domain-containing ion transport regulator 7 protein 20130301 {GO:0034220=TAS, GO:0005886=TAS, GO:0016020=IEA, GO:0051117=IEA, GO:0016021=IEA, GO:0055085=TAS, GO:0005216=IEA, GO:0043269=IEA} ion transmembrane transport, regulation of ion transport, transmembrane transport integral to membrane, membrane, plasma membrane ATPase binding, ion channel activity Human FYB IntAct UniProtKB {GO:0005515=PMID:22074159, GO:0050852=Reactome:REACT_12526, GO:0005102=PMID:10747096, GO:0005634=GO_REF:0000039, GO:0015629=PMID:10747096, GO:0032403=GO_REF:0000019, GO:0006607=PMID:9207119, GO:0007243=PMID:9207119, GO:0005829=Reactome:REACT_23963, GO:0008150=GO_REF:0000015, GO:0007165=PMID:9207119, GO:0006955=PMID:9207119, GO:0006468=PMID:9207119} O15117 FYN-binding protein protein 20130415 {GO:0005515=IPI, GO:0050852=TAS, GO:0005102=TAS, GO:0005634=IEA, GO:0015629=TAS, GO:0032403=IEA, GO:0006607=TAS, GO:0007243=TAS, GO:0005829=TAS, GO:0008150=ND, GO:0007165=TAS, GO:0006955=TAS, GO:0006468=TAS} NLS-bearing substrate import into nucleus, T cell receptor signaling pathway, biological_process, immune response, intracellular protein kinase cascade, protein phosphorylation, signal transduction actin cytoskeleton, cytosol, nucleus protein binding, protein complex binding, receptor binding Human UniProtKB:P16333 FYCO1 IntAct UniProtKB {GO:0005515=PMID:20562859, GO:0005776=PMID:20100911, GO:0005770=PMID:20100911, GO:0006810=GO_REF:0000002, GO:0072383=PMID:20100911, GO:0031410=GO_REF:0000037, GO:0016021=GO_REF:0000002, GO:0005764=PMID:20100911, GO:0046872=GO_REF:0000037} Q9BQS8 FYVE and coiled-coil domain-containing protein 1 protein 20130415 {GO:0005515=IPI, GO:0005776=IDA, GO:0005770=IDA, GO:0006810=IEA, GO:0072383=IMP, GO:0031410=IEA, GO:0016021=IEA, GO:0005764=IDA, GO:0046872=IEA} plus-end-directed vesicle transport along microtubule, transport autophagic vacuole, cytoplasmic vesicle, integral to membrane, late endosome, lysosome metal ion binding, protein binding Human UniProtKB:Q9H0R8 FYN UniProtKB UniProtKB {GO:0005515=PMID:22939624, GO:0008360=GO_REF:0000019, GO:0050900=Reactome:REACT_12051, GO:0007243=PMID:1361685, GO:0042802=PMID:14993658, GO:0042608=GO_REF:0000019, GO:0001948=PMID:16831868, GO:0046777=GO_REF:0000019, GO:0042609=GO_REF:0000019, GO:0007173=Reactome:REACT_9417, GO:0007411=Reactome:REACT_18266, GO:0007612=PMID:1361685, GO:0030168=Reactome:REACT_798, GO:0014069=GO_REF:0000019, GO:0018108=GO_REF:0000019, GO:0044325=GO_REF:0000019, GO:0046875=PMID:10498895, GO:0008543=Reactome:REACT_9470, GO:0045087=Reactome:REACT_6802, GO:0010976=GO_REF:0000019, GO:0038096=Reactome:REACT_160123, GO:0043548=GO_REF:0000019, GO:0050852=PMID:7722293, GO:0007631=PMID:8264796, GO:0005886=PMID:15611048, GO:0045471=GO_REF:0000019, GO:0031295=Reactome:REACT_19344, GO:0005634=GO_REF:0000039, GO:0051428=GO_REF:0000019, GO:0046872=GO_REF:0000037, GO:0005829=Reactome:REACT_160304, GO:0005739=GO_REF:0000019, GO:0015631=GO_REF:0000019, GO:0071375=GO_REF:0000019, GO:2001240=GO_REF:0000019, GO:0016032=Reactome:REACT_6185, GO:0050966=GO_REF:0000019, GO:0006816=PMID:7822789, GO:0048011=Reactome:REACT_11061, GO:0042610=GO_REF:0000019, GO:0042177=GO_REF:0000019, GO:0048015=Reactome:REACT_12464, GO:0042493=GO_REF:0000019, GO:0005524=GO_REF:0000038, GO:0050690=Reactome:REACT_11068, GO:0048813=GO_REF:0000019, GO:0016020=GO_REF:0000019, GO:0071363=GO_REF:0000019, GO:0007596=Reactome:REACT_604, GO:0019048=GO_REF:0000037, GO:0010629=GO_REF:0000019, GO:0050798=GO_REF:0000019, GO:0006468=PMID:7822789, GO:0030900=GO_REF:0000019, GO:0004713=GO_REF:0000038, GO:0001764=GO_REF:0000019, GO:0004715=PMID:7822789, GO:0007166=GO_REF:0000019, GO:0005768=PMID:15611048} Q5R3A8 Tyrosine-protein kinase Fyn protein 20130413 {GO:0005515=IPI, GO:0008360=IEA, GO:0050900=TAS, GO:0007243=TAS, GO:0042802=IPI, GO:0042608=IEA, GO:0001948=IPI, GO:0046777=IEA, GO:0042609=IEA, GO:0007173=TAS, GO:0007411=TAS, GO:0007612=TAS, GO:0030168=TAS, GO:0014069=IEA, GO:0018108=IEA, GO:0044325=IEA, GO:0046875=IPI, GO:0008543=TAS, GO:0045087=TAS, GO:0010976=IEA, GO:0038096=TAS, GO:0043548=IEA, GO:0050852=IDA, GO:0007631=TAS, GO:0005886=IDA, GO:0045471=IEA, GO:0031295=TAS, GO:0005634=IEA, GO:0051428=IEA, GO:0046872=IEA, GO:0005829=TAS, GO:0005739=IEA, GO:0015631=IEA, GO:0071375=IEA, GO:2001240=IEA, GO:0016032=TAS, GO:0050966=IEA, GO:0006816=NAS, GO:0048011=TAS, GO:0042610=IEA, GO:0042177=IEA, GO:0048015=TAS, GO:0042493=IEA, GO:0005524=IEA, GO:0050690=TAS, GO:0048813=IEA, GO:0016020=IEA, GO:0071363=IEA, GO:0007596=TAS, GO:0019048=IEA, GO:0010629=IEA, GO:0050798=IEA, GO:0006468=NAS, GO:0030900=IEA, GO:0004713=IEA, GO:0001764=IEA, GO:0004715=NAS, GO:0007166=IEA, GO:0005768=IDA} Fc-gamma receptor signaling pathway involved in phagocytosis, T cell costimulation, T cell receptor signaling pathway, activated T cell proliferation, axon guidance, blood coagulation, calcium ion transport, cell surface receptor signaling pathway, cellular response to growth factor stimulus, cellular response to peptide hormone stimulus, dendrite morphogenesis, detection of mechanical stimulus involved in sensory perception of pain, epidermal growth factor receptor signaling pathway, feeding behavior, fibroblast growth factor receptor signaling pathway, forebrain development, innate immune response, intracellular protein kinase cascade, learning, leukocyte migration, negative regulation of extrinsic apoptotic signaling pathway in absence of ligand, negative regulation of gene expression, negative regulation of protein catabolic process, neuron migration, neurotrophin TRK receptor signaling pathway, peptidyl-tyrosine phosphorylation, phosphatidylinositol-mediated signaling, platelet activation, positive regulation of neuron projection development, protein autophosphorylation, protein phosphorylation, regulation of cell shape, regulation of defense response to virus by virus, response to drug, response to ethanol, viral reproduction, virus-host interaction cytosol, endosome, membrane, mitochondrion, nucleus, plasma membrane, postsynaptic density ATP binding, CD4 receptor binding, CD8 receptor binding, T cell receptor binding, ephrin receptor binding, glycoprotein binding, identical protein binding, ion channel binding, metal ion binding, non-membrane spanning protein tyrosine kinase activity, peptide hormone receptor binding, phosphatidylinositol 3-kinase binding, protein binding, protein tyrosine kinase activity, tubulin binding Human UniProtKB-KW:KW-0067 FYTTD1 UniProtKB UniProtKB {GO:0005515=PMID:19836239, GO:0006406=PMID:19836239, GO:0016607=PMID:19836239, GO:0005654=PMID:19836239, GO:0003729=PMID:19836239} Q96QD9 UAP56-interacting factor protein 20091203 {GO:0005515=IPI, GO:0006406=IMP, GO:0016607=IDA, GO:0005654=IDA, GO:0003729=IDA} mRNA export from nucleus nuclear speck, nucleoplasm mRNA binding, protein binding Human FZD1 BHF-UCL UniProtKB {GO:0008406=GO_REF:0000033, GO:0005515=PMID:19277043, GO:0017147=PMID:10557084, GO:0007199=GO_REF:0000033, GO:0007267=PMID:10557084, GO:0044339=PMID:20039315, GO:0044338=PMID:20039315, GO:0007409=GO_REF:0000033, GO:0009790=GO_REF:0000033, GO:0035414=GO_REF:0000019, GO:0007223=GO_REF:0000033, GO:0030514=GO_REF:0000033, GO:0051091=PMID:14739301, GO:0005737=GO_REF:0000033, GO:0030182=GO_REF:0000024, GO:0030855=GO_REF:0000033, GO:0060070=PMID:14739301, GO:0090090=GO_REF:0000033, GO:0060022=GO_REF:0000019, GO:0001944=GO_REF:0000033, GO:0042813=PMID:10557084, GO:0003150=GO_REF:0000019, GO:0009986=PMID:19643732, GO:0048286=GO_REF:0000033, GO:0004930=GO_REF:0000037, GO:0042493=PMID:19421142, GO:0005102=PMID:14739301, GO:0090179=GO_REF:0000019, GO:0045177=GO_REF:0000033, GO:0035425=PMID:10557084, GO:0030165=PMID:19388021, GO:0032589=GO_REF:0000033, GO:0003151=GO_REF:0000019, GO:0007420=GO_REF:0000033, GO:0003149=GO_REF:0000019, GO:0001934=GO_REF:0000019, GO:0016021=GO_REF:0000037, GO:0045893=PMID:18929644, GO:0045892=GO_REF:0000019} Q9UP38 Frizzled-1 protein 20100930 {GO:0008406=IBA, GO:0005515=IPI, GO:0017147=IPI, GO:0007199=IBA, GO:0007267=IDA, GO:0044339=IMP, GO:0044338=IMP, GO:0007409=IBA, GO:0009790=IBA, GO:0035414=IEA, GO:0007223=IBA, GO:0030514=IBA, GO:0051091=IDA, GO:0005737=IBA, GO:0030182=ISS, GO:0030855=IBA, GO:0060070=IDA, GO:0090090=IBA, GO:0060022=IEA, GO:0001944=IBA, GO:0042813=IDA, GO:0003150=IEA, GO:0009986=IDA, GO:0048286=IBA, GO:0004930=IEA, GO:0042493=IMP, GO:0005102=IPI, GO:0090179=IEA, GO:0045177=IBA, GO:0035425=IDA, GO:0030165=IPI, GO:0032589=IBA, GO:0003151=IEA, GO:0007420=IBA, GO:0003149=IEA, GO:0001934=IEA, GO:0016021=IEA, GO:0045893=IDA, GO:0045892=IEA} G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger, Wnt receptor signaling pathway, calcium modulating pathway, autocrine signaling, axonogenesis, brain development, canonical Wnt receptor signaling pathway, canonical Wnt receptor signaling pathway involved in mesenchymal stem cell differentiation, canonical Wnt receptor signaling pathway involved in osteoblast differentiation, cell-cell signaling, embryo development, epithelial cell differentiation, gonad development, hard palate development, lung alveolus development, membranous septum morphogenesis, muscular septum morphogenesis, negative regulation of BMP signaling pathway, negative regulation of canonical Wnt receptor signaling pathway, negative regulation of catenin import into nucleus, negative regulation of transcription, DNA-dependent, neuron differentiation, outflow tract morphogenesis, planar cell polarity pathway involved in neural tube closure, positive regulation of protein phosphorylation, positive regulation of sequence-specific DNA binding transcription factor activity, positive regulation of transcription, DNA-dependent, response to drug, vasculature development apical part of cell, cell surface, cytoplasm, integral to membrane, neuron projection membrane G-protein coupled receptor activity, PDZ domain binding, Wnt-activated receptor activity, Wnt-protein binding, protein binding, receptor binding Human FZD10 BHF-UCL UniProtKB {GO:0005515=PMID:15930302, GO:0008406=GO_REF:0000033, GO:0042813=GO_REF:0000033, GO:0017147=GO_REF:0000033, GO:0009986=PMID:18271942, GO:0005886=GO_REF:0000033, GO:0034259=PMID:19137009, GO:0004930=GO_REF:0000037, GO:0071300=GO_REF:0000024, GO:0038031=PMID:19137009, GO:0009790=GO_REF:0000033, GO:0042995=GO_REF:0000033, GO:0030165=GO_REF:0000033, GO:0032855=PMID:19137009, GO:0005737=PMID:16007199, GO:0005887=PMID:10448064, GO:0007420=GO_REF:0000033, GO:0032956=PMID:19137009, GO:0030182=GO_REF:0000024, GO:0043507=PMID:19137009, GO:0060070=GO_REF:0000033, GO:0001944=GO_REF:0000033} Q9ULW2 Frizzled-10 protein 20120404 {GO:0005515=IPI, GO:0008406=IBA, GO:0042813=IBA, GO:0017147=IBA, GO:0009986=IDA, GO:0005886=IBA, GO:0034259=IMP, GO:0004930=IEA, GO:0071300=ISS, GO:0038031=IMP, GO:0009790=IBA, GO:0042995=IBA, GO:0030165=IBA, GO:0032855=IMP, GO:0005737=IDA, GO:0005887=TAS, GO:0007420=IBA, GO:0032956=IMP, GO:0030182=ISS, GO:0043507=IMP, GO:0060070=IBA, GO:0001944=IBA} brain development, canonical Wnt receptor signaling pathway, cellular response to retinoic acid, embryo development, gonad development, negative regulation of Rho GTPase activity, neuron differentiation, non-canonical Wnt receptor signaling pathway via JNK cascade, positive regulation of JUN kinase activity, positive regulation of Rac GTPase activity, regulation of actin cytoskeleton organization, vasculature development cell projection, cell surface, cytoplasm, integral to plasma membrane, plasma membrane G-protein coupled receptor activity, PDZ domain binding, Wnt-activated receptor activity, Wnt-protein binding, protein binding Human FZD2 BHF-UCL UniProtKB {GO:0008406=GO_REF:0000033, GO:0007608=GO_REF:0000019, GO:0017147=GO_REF:0000033, GO:0005886=PMID:18929644, GO:0007199=GO_REF:0000033, GO:0007267=GO_REF:0000019, GO:0007409=GO_REF:0000033, GO:0009790=GO_REF:0000033, GO:0007223=GO_REF:0000033, GO:0005737=PMID:19038973, GO:0051091=PMID:18929644, GO:0030182=GO_REF:0000024, GO:0030855=GO_REF:0000033, GO:0090103=GO_REF:0000019, GO:0060070=PMID:18215320, GO:0060022=GO_REF:0000019, GO:0001944=GO_REF:0000033, GO:0042813=GO_REF:0000033, GO:0003150=GO_REF:0000019, GO:0004930=GO_REF:0000037, GO:0090179=GO_REF:0000019, GO:0060119=GO_REF:0000019, GO:0045177=GO_REF:0000033, GO:0032589=GO_REF:0000033, GO:0030165=PMID:19388021, GO:0003151=GO_REF:0000019, GO:0007420=GO_REF:0000033, GO:0003149=GO_REF:0000019, GO:0030825=PMID:19946729, GO:0016021=GO_REF:0000037, GO:0045893=PMID:18215320} Q14332 Frizzled-2 protein 20100818 {GO:0008406=IBA, GO:0007608=IEA, GO:0017147=IBA, GO:0005886=IDA, GO:0007199=IBA, GO:0007267=IEA, GO:0007409=IBA, GO:0009790=IBA, GO:0007223=IBA, GO:0005737=IDA, GO:0051091=IDA, GO:0030182=ISS, GO:0030855=IBA, GO:0090103=IEA, GO:0060070=IDA, GO:0060022=IEA, GO:0001944=IBA, GO:0042813=IBA, GO:0003150=IEA, GO:0004930=IEA, GO:0090179=IEA, GO:0060119=IEA, GO:0045177=IBA, GO:0032589=IBA, GO:0030165=IPI, GO:0003151=IEA, GO:0007420=IBA, GO:0003149=IEA, GO:0030825=IMP, GO:0016021=IEA, GO:0045893=IDA} G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger, Wnt receptor signaling pathway, calcium modulating pathway, axonogenesis, brain development, canonical Wnt receptor signaling pathway, cell-cell signaling, cochlea morphogenesis, embryo development, epithelial cell differentiation, gonad development, hard palate development, inner ear receptor cell development, membranous septum morphogenesis, muscular septum morphogenesis, neuron differentiation, outflow tract morphogenesis, planar cell polarity pathway involved in neural tube closure, positive regulation of cGMP metabolic process, positive regulation of sequence-specific DNA binding transcription factor activity, positive regulation of transcription, DNA-dependent, sensory perception of smell, vasculature development apical part of cell, cytoplasm, integral to membrane, neuron projection membrane, plasma membrane G-protein coupled receptor activity, PDZ domain binding, Wnt-activated receptor activity, Wnt-protein binding Human FZD3 BHF-UCL UniProtKB {GO:0001736=GO_REF:0000033, GO:0008406=GO_REF:0000033, GO:0005515=PMID:19277043, GO:0017147=PMID:19038973, GO:0030424=GO_REF:0000033, GO:0005886=PMID:19038973, GO:0071679=GO_REF:0000033, GO:0007199=GO_REF:0000033, GO:0030425=GO_REF:0000033, GO:0005737=PMID:19038973, GO:0033278=GO_REF:0000033, GO:0016324=GO_REF:0000019, GO:0030182=GO_REF:0000024, GO:0043025=GO_REF:0000033, GO:0060070=PMID:20802536, GO:0001942=GO_REF:0000019, GO:0001944=GO_REF:0000033, GO:0042813=PMID:19038973, GO:0048786=GO_REF:0000033, GO:0042472=GO_REF:0000033, GO:0004930=GO_REF:0000037, GO:0001843=GO_REF:0000033, GO:0045177=GO_REF:0000033, GO:0032589=GO_REF:0000033, GO:0030165=PMID:18256285, GO:0036342=GO_REF:0000019, GO:0021754=GO_REF:0000033, GO:0016021=GO_REF:0000037, GO:0001764=GO_REF:0000019} Q9NPG1 Frizzled-3 protein 20100818 {GO:0001736=IBA, GO:0008406=IBA, GO:0005515=IPI, GO:0017147=IPI, GO:0030424=IBA, GO:0005886=IDA, GO:0071679=IBA, GO:0007199=IBA, GO:0030425=IBA, GO:0005737=IDA, GO:0033278=IBA, GO:0016324=IEA, GO:0030182=ISS, GO:0043025=IBA, GO:0060070=IDA, GO:0001942=IEA, GO:0001944=IBA, GO:0042813=IC, GO:0048786=IBA, GO:0042472=IBA, GO:0004930=IEA, GO:0001843=IBA, GO:0045177=IBA, GO:0032589=IBA, GO:0030165=IPI, GO:0036342=IEA, GO:0021754=IBA, GO:0016021=IEA, GO:0001764=IEA} G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger, canonical Wnt receptor signaling pathway, cell proliferation in midbrain, commissural neuron axon guidance, establishment of planar polarity, facial nucleus development, gonad development, hair follicle development, inner ear morphogenesis, neural tube closure, neuron differentiation, neuron migration, post-anal tail morphogenesis, vasculature development apical part of cell, apical plasma membrane, axon, cytoplasm, dendrite, integral to membrane, neuron projection membrane, neuronal cell body, plasma membrane, presynaptic active zone G-protein coupled receptor activity, PDZ domain binding, Wnt-activated receptor activity, Wnt-protein binding, protein binding Human FZD4 BHF-UCL UniProtKB {GO:0005515=PMID:20802536, GO:0017147=GO_REF:0000033, GO:0030947=GO_REF:0000033, GO:0005886=PMID:14688793, GO:0071300=GO_REF:0000024, GO:0007605=GO_REF:0000019, GO:0010812=PMID:18156211, GO:0042701=GO_REF:0000033, GO:0061299=PMID:15024691, GO:0009790=GO_REF:0000033, GO:0042995=GO_REF:0000033, GO:0042803=PMID:14688793, GO:0007223=PMID:12172548, GO:0051091=PMID:14688793, GO:0005737=GO_REF:0000033, GO:0005911=GO_REF:0000019, GO:0030182=GO_REF:0000024, GO:0034446=GO_REF:0000033, GO:0043507=GO_REF:0000019, GO:0016055=PMID:14688793, GO:0060070=PMID:15035989, GO:0031625=PMID:22575959, GO:0042813=PMID:17955262, GO:0046982=PMID:14688793, GO:0009986=PMID:19643732, GO:0004930=GO_REF:0000037, GO:0031987=GO_REF:0000019, GO:0035426=GO_REF:0000019, GO:0030165=PMID:20802536, GO:0019955=PMID:17955262, GO:0061304=GO_REF:0000019, GO:0007420=GO_REF:0000033, GO:0005887=PMID:17955262, GO:0045893=PMID:17955262, GO:0001570=GO_REF:0000033, GO:0061301=GO_REF:0000019} Q9ULV1 Frizzled-4 protein 20100806 {GO:0005515=IPI, GO:0017147=IBA, GO:0030947=IBA, GO:0005886=IDA, GO:0071300=ISS, GO:0007605=IEA, GO:0010812=IMP, GO:0042701=IBA, GO:0061299=IMP, GO:0009790=IBA, GO:0042995=IBA, GO:0042803=IPI, GO:0007223=IDA, GO:0051091=IDA, GO:0005737=IBA, GO:0005911=IEA, GO:0030182=ISS, GO:0034446=IBA, GO:0043507=IEA, GO:0016055=IDA, GO:0060070=IDA, GO:0031625=IPI, GO:0042813=IDA, GO:0046982=IPI, GO:0009986=IDA, GO:0004930=IEA, GO:0031987=IEA, GO:0035426=IEA, GO:0030165=IDA, GO:0019955=IPI, GO:0061304=IEA, GO:0007420=IBA, GO:0005887=IC, GO:0045893=IDA, GO:0001570=IBA, GO:0061301=IEA} Wnt receptor signaling pathway, Wnt receptor signaling pathway, calcium modulating pathway, brain development, canonical Wnt receptor signaling pathway, cellular response to retinoic acid, cerebellum vasculature morphogenesis, embryo development, extracellular matrix-cell signaling, locomotion involved in locomotory behavior, negative regulation of cell-substrate adhesion, neuron differentiation, positive regulation of JUN kinase activity, positive regulation of sequence-specific DNA binding transcription factor activity, positive regulation of transcription, DNA-dependent, progesterone secretion, regulation of vascular endothelial growth factor receptor signaling pathway, retina vasculature morphogenesis in camera-type eye, retinal blood vessel morphogenesis, sensory perception of sound, substrate adhesion-dependent cell spreading, vasculogenesis cell projection, cell surface, cell-cell junction, cytoplasm, integral to plasma membrane, plasma membrane G-protein coupled receptor activity, PDZ domain binding, Wnt-activated receptor activity, Wnt-protein binding, cytokine binding, protein binding, protein heterodimerization activity, protein homodimerization activity, ubiquitin protein ligase binding Human FZD5 BHF-UCL UniProtKB {GO:0008406=GO_REF:0000033, GO:0005515=PMID:18838381, GO:0017147=PMID:12490564, GO:0048471=GO_REF:0000019, GO:0008285=GO_REF:0000019, GO:0005886=Reactome:REACT_21306, GO:0007409=GO_REF:0000033, GO:0042995=GO_REF:0000033, GO:0044332=PMID:11029007, GO:0005737=GO_REF:0000033, GO:0031076=GO_REF:0000033, GO:0000578=PMID:12121999, GO:0045944=PMID:10906785, GO:0030182=GO_REF:0000024, GO:0060716=GO_REF:0000033, GO:0048469=GO_REF:0000019, GO:0043507=GO_REF:0000019, GO:0008595=PMID:9054360, GO:0060070=PMID:12121999, GO:0071219=PMID:16601243, GO:0031625=PMID:22575959, GO:0032729=PMID:16601243, GO:0042813=PMID:9054360, GO:0033077=GO_REF:0000033, GO:0009986=PMID:19643732, GO:0019901=PMID:19643732, GO:0004930=GO_REF:0000037, GO:0006915=GO_REF:0000033, GO:0060561=GO_REF:0000019, GO:0001525=GO_REF:0000033, GO:0030165=GO_REF:0000033, GO:0031077=GO_REF:0000033, GO:0000139=GO_REF:0000039, GO:0007420=GO_REF:0000033, GO:0016021=GO_REF:0000037, GO:0060061=PMID:9054360} Q13467 Frizzled-5 protein 20110204 {GO:0008406=IBA, GO:0005515=IPI, GO:0017147=IPI, GO:0048471=IEA, GO:0008285=IEA, GO:0005886=TAS, GO:0007409=IBA, GO:0042995=IBA, GO:0044332=IDA, GO:0005737=IBA, GO:0031076=IBA, GO:0000578=IDA, GO:0045944=IGI, GO:0030182=ISS, GO:0060716=IBA, GO:0048469=IEA, GO:0043507=IEA, GO:0008595=IDA, GO:0060070=IDA, GO:0071219=IDA, GO:0031625=IPI, GO:0032729=IMP, GO:0042813=IC, GO:0033077=IBA, GO:0009986=IDA, GO:0019901=IPI, GO:0004930=IEA, GO:0006915=IBA, GO:0060561=IEA, GO:0001525=IBA, GO:0030165=IBA, GO:0031077=IBA, GO:0000139=IEA, GO:0007420=IBA, GO:0016021=IEA, GO:0060061=IDA} Spemann organizer formation, T cell differentiation in thymus, Wnt receptor signaling pathway involved in dorsal/ventral axis specification, angiogenesis, anterior/posterior axis specification, embryo, apoptotic process, apoptotic process involved in morphogenesis, axonogenesis, brain development, canonical Wnt receptor signaling pathway, cell maturation, cellular response to molecule of bacterial origin, embryonic axis specification, embryonic camera-type eye development, gonad development, labyrinthine layer blood vessel development, negative regulation of cell proliferation, neuron differentiation, positive regulation of JUN kinase activity, positive regulation of interferon-gamma production, positive regulation of transcription from RNA polymerase II promoter, post-embryonic camera-type eye development Golgi membrane, cell projection, cell surface, cytoplasm, integral to membrane, perinuclear region of cytoplasm, plasma membrane G-protein coupled receptor activity, PDZ domain binding, Wnt-activated receptor activity, Wnt-protein binding, protein binding, protein kinase binding, ubiquitin protein ligase binding Human FZD6 HPA UniProtKB {GO:0001736=GO_REF:0000033, GO:0008406=GO_REF:0000033, GO:0005515=PMID:10347172, GO:0017147=PMID:15265686, GO:0005886=GO_REF:0000052, GO:0007199=GO_REF:0000033, GO:0007409=GO_REF:0000033, GO:0043433=PMID:14747478, GO:0005737=GO_REF:0000033, GO:0033278=GO_REF:0000033, GO:0016055=GO_REF:0000038, GO:0090090=PMID:14747478, GO:0001942=GO_REF:0000019, GO:0060071=GO_REF:0000019, GO:0031625=PMID:22575959, GO:0042813=PMID:10347172, GO:0042472=GO_REF:0000033, GO:0004930=GO_REF:0000037, GO:0001843=GO_REF:0000033, GO:0030168=GO_REF:0000019, GO:0045177=GO_REF:0000033, GO:0007275=GO_REF:0000038, GO:0001525=GO_REF:0000033, GO:0030165=GO_REF:0000033, GO:0032589=GO_REF:0000033, GO:0016327=GO_REF:0000033, GO:0005887=PMID:15265686, GO:0016021=GO_REF:0000038, GO:0035567=PMID:14747478} O60353 Frizzled-6 protein 20090616 {GO:0001736=IBA, GO:0008406=IBA, GO:0005515=IPI, GO:0017147=ISS, GO:0005886=IDA, GO:0007199=IBA, GO:0007409=IBA, GO:0043433=IDA, GO:0005737=IBA, GO:0033278=IBA, GO:0016055=IEA, GO:0090090=IMP, GO:0001942=IEA, GO:0060071=IEA, GO:0031625=IPI, GO:0042813=IDA, GO:0042472=IBA, GO:0004930=IEA, GO:0001843=IBA, GO:0030168=IEA, GO:0045177=IBA, GO:0007275=IEA, GO:0001525=IBA, GO:0030165=IBA, GO:0032589=IBA, GO:0016327=IBA, GO:0005887=ISS, GO:0016021=IEA, GO:0035567=IDA} G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger, Wnt receptor signaling pathway, Wnt receptor signaling pathway, planar cell polarity pathway, angiogenesis, axonogenesis, cell proliferation in midbrain, establishment of planar polarity, gonad development, hair follicle development, inner ear morphogenesis, multicellular organismal development, negative regulation of canonical Wnt receptor signaling pathway, negative regulation of sequence-specific DNA binding transcription factor activity, neural tube closure, non-canonical Wnt receptor signaling pathway, platelet activation apical part of cell, apicolateral plasma membrane, cytoplasm, integral to membrane, integral to plasma membrane, neuron projection membrane, plasma membrane G-protein coupled receptor activity, PDZ domain binding, Wnt-activated receptor activity, Wnt-protein binding, protein binding, ubiquitin protein ligase binding Human FZD7 BHF-UCL UniProtKB {GO:0008406=GO_REF:0000033, GO:0048103=GO_REF:0000019, GO:0017147=PMID:18313787, GO:0005886=PMID:18256285, GO:0071300=GO_REF:0000024, GO:0038031=PMID:19773752, GO:0007199=GO_REF:0000033, GO:0010812=PMID:18156211, GO:0046330=PMID:18256285, GO:0007409=GO_REF:0000033, GO:0042666=PMID:18681827, GO:0007223=GO_REF:0000033, GO:0035412=PMID:9707618, GO:0005737=GO_REF:0000033, GO:0030182=GO_REF:0000024, GO:0034446=GO_REF:0000019, GO:0014834=GO_REF:0000019, GO:0060070=PMID:19773752, GO:0001944=GO_REF:0000033, GO:0042813=GO_REF:0000033, GO:0060054=PMID:18313787, GO:0006355=PMID:18681827, GO:0033077=GO_REF:0000019, GO:0004930=GO_REF:0000037, GO:0060231=PMID:17016432, GO:0045177=GO_REF:0000033, GO:0032589=GO_REF:0000033, GO:0030165=PMID:18256285, GO:0007420=GO_REF:0000033, GO:0019827=PMID:18681827, GO:0016021=PMID:9707618, GO:0045893=PMID:19773752, GO:0042327=PMID:18256285} O75084 Frizzled-7 protein 20100806 {GO:0008406=IBA, GO:0048103=IEA, GO:0017147=IPI, GO:0005886=IDA, GO:0071300=ISS, GO:0038031=IMP, GO:0007199=IBA, GO:0010812=IMP, GO:0046330=IC, GO:0007409=IBA, GO:0042666=IMP, GO:0007223=IBA, GO:0035412=IMP, GO:0005737=IBA, GO:0030182=ISS, GO:0034446=IEA, GO:0014834=IEA, GO:0060070=IMP, GO:0001944=IBA, GO:0042813=IBA, GO:0060054=IMP, GO:0006355=IMP, GO:0033077=IEA, GO:0004930=IEA, GO:0060231=IMP, GO:0045177=IBA, GO:0032589=IBA, GO:0030165=IPI, GO:0007420=IBA, GO:0019827=IMP, GO:0016021=TAS, GO:0045893=IMP, GO:0042327=IDA} G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger, T cell differentiation in thymus, Wnt receptor signaling pathway, calcium modulating pathway, axonogenesis, brain development, canonical Wnt receptor signaling pathway, cellular response to retinoic acid, gonad development, mesenchymal to epithelial transition, negative regulation of cell-substrate adhesion, negative regulation of ectodermal cell fate specification, neuron differentiation, non-canonical Wnt receptor signaling pathway via JNK cascade, positive regulation of JNK cascade, positive regulation of epithelial cell proliferation involved in wound healing, positive regulation of phosphorylation, positive regulation of transcription, DNA-dependent, regulation of catenin import into nucleus, regulation of transcription, DNA-dependent, satellite cell maintenance involved in skeletal muscle regeneration, somatic stem cell division, stem cell maintenance, substrate adhesion-dependent cell spreading, vasculature development apical part of cell, cytoplasm, integral to membrane, neuron projection membrane, plasma membrane G-protein coupled receptor activity, PDZ domain binding, Wnt-activated receptor activity, Wnt-protein binding Human FZD8 BHF-UCL UniProtKB {GO:0005515=PMID:22682250, GO:0042813=PMID:11295046, GO:0008406=GO_REF:0000033, GO:0017147=GO_REF:0000033, GO:0033077=GO_REF:0000033, GO:0005794=GO_REF:0000039, GO:0005886=GO_REF:0000033, GO:0004930=GO_REF:0000037, GO:0005102=GO_REF:0000019, GO:0042995=GO_REF:0000033, GO:0000122=GO_REF:0000019, GO:0007409=GO_REF:0000033, GO:0009790=GO_REF:0000033, GO:0030165=PMID:18256285, GO:0005737=GO_REF:0000033, GO:0007420=GO_REF:0000033, GO:0030182=GO_REF:0000024, GO:0045944=GO_REF:0000019, GO:0016021=PMID:11295046, GO:0043507=GO_REF:0000019, GO:0060070=GO_REF:0000033, GO:0031625=PMID:22575959, GO:0001944=GO_REF:0000033} Q9H461 Frizzled-8 protein 20100810 {GO:0005515=IPI, GO:0042813=TAS, GO:0008406=IBA, GO:0017147=IBA, GO:0033077=IBA, GO:0005794=IEA, GO:0005886=IBA, GO:0004930=IEA, GO:0005102=IEA, GO:0042995=IBA, GO:0000122=IEA, GO:0007409=IBA, GO:0009790=IBA, GO:0030165=IPI, GO:0005737=IBA, GO:0007420=IBA, GO:0030182=ISS, GO:0045944=IEA, GO:0016021=TAS, GO:0043507=IEA, GO:0060070=IBA, GO:0031625=IPI, GO:0001944=IBA} T cell differentiation in thymus, axonogenesis, brain development, canonical Wnt receptor signaling pathway, embryo development, gonad development, negative regulation of transcription from RNA polymerase II promoter, neuron differentiation, positive regulation of JUN kinase activity, positive regulation of transcription from RNA polymerase II promoter, vasculature development Golgi apparatus, cell projection, cytoplasm, integral to membrane, plasma membrane G-protein coupled receptor activity, PDZ domain binding, Wnt-activated receptor activity, Wnt-protein binding, protein binding, receptor binding, ubiquitin protein ligase binding Human UniProtKB:O00560 FZD9 BHF-UCL UniProtKB {GO:0008406=GO_REF:0000033, GO:0042813=GO_REF:0000033, GO:0017147=PMID:19038973, GO:0048471=GO_REF:0000033, GO:0046982=PMID:14688793, GO:0009986=PMID:20458727, GO:0005886=PMID:19038973, GO:0004930=GO_REF:0000037, GO:0031527=GO_REF:0000033, GO:0009790=GO_REF:0000033, GO:0030165=GO_REF:0000033, GO:0042803=PMID:14688793, GO:0007399=PMID:9147651, GO:0007405=GO_REF:0000033, GO:0005737=PMID:19038973, GO:0007420=GO_REF:0000033, GO:0030183=GO_REF:0000033, GO:0007611=GO_REF:0000019, GO:0016021=GO_REF:0000037, GO:0060070=GO_REF:0000033, GO:0001944=GO_REF:0000033} O00144 Frizzled-9 protein 20100818 {GO:0008406=IBA, GO:0042813=IBA, GO:0017147=IPI, GO:0048471=IBA, GO:0046982=IPI, GO:0009986=IDA, GO:0005886=IDA, GO:0004930=IEA, GO:0031527=IBA, GO:0009790=IBA, GO:0030165=IBA, GO:0042803=IPI, GO:0007399=TAS, GO:0007405=IBA, GO:0005737=IDA, GO:0007420=IBA, GO:0030183=IBA, GO:0007611=IEA, GO:0016021=IEA, GO:0060070=IBA, GO:0001944=IBA} B cell differentiation, brain development, canonical Wnt receptor signaling pathway, embryo development, gonad development, learning or memory, nervous system development, neuroblast proliferation, vasculature development cell surface, cytoplasm, filopodium membrane, integral to membrane, perinuclear region of cytoplasm, plasma membrane G-protein coupled receptor activity, PDZ domain binding, Wnt-activated receptor activity, Wnt-protein binding, protein heterodimerization activity, protein homodimerization activity Human FZR1 HPA UniProtKB {GO:0005515=PMID:22770219, GO:0031965=GO_REF:0000052, GO:0008284=GO_REF:0000019, GO:0045732=PMID:11459825, GO:0070306=GO_REF:0000019, GO:0031572=PMID:18662541, GO:0005730=GO_REF:0000052, GO:0051437=Reactome:REACT_6821, GO:0090344=GO_REF:0000019, GO:0005634=GO_REF:0000052, GO:0051436=Reactome:REACT_6785, GO:0031145=Reactome:REACT_6828, GO:0051439=Reactome:REACT_6867, GO:0005829=Reactome:REACT_9035, GO:0051488=PMID:11459826, GO:0000084=Reactome:REACT_899, GO:0040020=GO_REF:0000019, GO:0007067=GO_REF:0000037, GO:0006281=GO_REF:0000037, GO:0070979=PMID:21596315, GO:0005680=PMID:11459825, GO:0005654=Reactome:REACT_9051, GO:0000278=Reactome:REACT_152, GO:0051301=GO_REF:0000037} Q9UM11 Fizzy-related protein homolog protein 20120912 {GO:0005515=IPI, GO:0031965=IDA, GO:0008284=IEA, GO:0045732=IGI, GO:0070306=IEA, GO:0031572=IDA, GO:0005730=IDA, GO:0051437=TAS, GO:0090344=IEA, GO:0005634=IDA, GO:0051436=TAS, GO:0031145=TAS, GO:0051439=TAS, GO:0005829=TAS, GO:0051488=IDA, GO:0000084=TAS, GO:0040020=IEA, GO:0007067=IEA, GO:0006281=IEA, GO:0070979=TAS, GO:0005680=IDA, GO:0005654=TAS, GO:0000278=TAS, GO:0051301=IEA} DNA repair, G2 DNA damage checkpoint, S phase of mitotic cell cycle, activation of anaphase-promoting complex activity, anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process, cell division, lens fiber cell differentiation, mitosis, mitotic cell cycle, negative regulation of cell aging, negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle, positive regulation of cell proliferation, positive regulation of protein catabolic process, positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle, protein K11-linked ubiquitination, regulation of meiosis, regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle anaphase-promoting complex, cytosol, nuclear membrane, nucleolus, nucleoplasm, nucleus protein binding Human G0S2 Reactome UniProtKB {GO:0005811=Reactome:REACT_115967, GO:0005515=PMID:19706769, GO:0005739=PMID:19706769, GO:0003674=GO_REF:0000015, GO:0043065=PMID:19706769, GO:0006915=PMID:19706769, GO:0044281=Reactome:REACT_111217, GO:0044255=Reactome:REACT_22279} P27469 G0/G1 switch protein 2 protein 20130301 {GO:0005811=TAS, GO:0005515=IPI, GO:0005739=IDA, GO:0003674=ND, GO:0043065=IDA, GO:0006915=IDA, GO:0044281=TAS, GO:0044255=TAS} apoptotic process, cellular lipid metabolic process, positive regulation of apoptotic process, small molecule metabolic process lipid particle, mitochondrion molecular_function, protein binding Human G2E3 HPA UniProtKB {GO:0000209=GO_REF:0000019, GO:0005737=GO_REF:0000052, GO:0043066=GO_REF:0000019, GO:0004842=GO_REF:0000019, GO:0005794=GO_REF:0000052, GO:0001824=GO_REF:0000019, GO:0005730=GO_REF:0000039, GO:0006915=GO_REF:0000037, GO:0008270=GO_REF:0000002, GO:0043231=GO_REF:0000052} Q7L622 G2/M phase-specific E3 ubiquitin-protein ligase protein 20101115 {GO:0000209=IEA, GO:0005737=IDA, GO:0043066=IEA, GO:0004842=IEA, GO:0005794=IDA, GO:0001824=IEA, GO:0005730=IEA, GO:0006915=IEA, GO:0008270=IEA, GO:0043231=IDA} apoptotic process, blastocyst development, negative regulation of apoptotic process, protein polyubiquitination Golgi apparatus, cytoplasm, intracellular membrane-bounded organelle, nucleolus ubiquitin-protein ligase activity, zinc ion binding Human G3BP1 HPA UniProtKB {GO:0005515=PMID:23209657, GO:0005886=GO_REF:0000039, GO:0010494=GO_REF:0000019, GO:0007265=PMID:8649363, GO:0005634=GO_REF:0000039, GO:0003729=GO_REF:0000019, GO:0003677=GO_REF:0000037, GO:0005524=GO_REF:0000037, GO:0005829=GO_REF:0000039, GO:0004004=PMID:9889278, GO:0005622=GO_REF:0000002, GO:0005737=GO_REF:0000052, GO:0004003=PMID:9889278, GO:0004519=GO_REF:0000037, GO:0000166=GO_REF:0000002, GO:0006810=GO_REF:0000037, GO:0090090=GO_REF:0000019} Q13283 Ras GTPase-activating protein-binding protein 1 protein 20080205 {GO:0005515=IPI, GO:0005886=IEA, GO:0010494=IEA, GO:0007265=TAS, GO:0005634=IEA, GO:0003729=IEA, GO:0003677=IEA, GO:0005524=IEA, GO:0005829=IEA, GO:0004004=TAS, GO:0005622=IEA, GO:0005737=IDA, GO:0004003=TAS, GO:0004519=IEA, GO:0000166=IEA, GO:0006810=IEA, GO:0090090=IEA} Ras protein signal transduction, negative regulation of canonical Wnt receptor signaling pathway, transport cytoplasm, cytoplasmic stress granule, cytosol, intracellular, nucleus, plasma membrane ATP binding, ATP-dependent DNA helicase activity, ATP-dependent RNA helicase activity, DNA binding, endonuclease activity, mRNA binding, nucleotide binding, protein binding Human G3BP2 HPA UniProtKB {GO:0005622=GO_REF:0000002, GO:0051056=Reactome:REACT_11051, GO:0005737=GO_REF:0000052, GO:0000166=GO_REF:0000002, GO:0007264=Reactome:REACT_11044, GO:0003723=GO_REF:0000029, GO:0007253=PMID:10969074, GO:0006810=GO_REF:0000002, GO:0030159=PMID:10969074, GO:0007265=PMID:9575347, GO:0051028=GO_REF:0000037, GO:0005829=Reactome:REACT_9982} Q9UN86 Ras GTPase-activating protein-binding protein 2 protein 20100326 {GO:0005622=IEA, GO:0051056=TAS, GO:0005737=IDA, GO:0000166=IEA, GO:0007264=TAS, GO:0003723=NAS, GO:0007253=NAS, GO:0006810=IEA, GO:0030159=NAS, GO:0007265=NAS, GO:0051028=IEA, GO:0005829=TAS} Ras protein signal transduction, cytoplasmic sequestering of NF-kappaB, mRNA transport, regulation of small GTPase mediated signal transduction, small GTPase mediated signal transduction, transport cytoplasm, cytosol, intracellular RNA binding, nucleotide binding, receptor signaling complex scaffold activity Human G6PC Reactome UniProtKB {GO:0010468=GO_REF:0000019, GO:0006094=PMID:8211187, GO:0015760=GO_REF:0000019, GO:0030176=PMID:10318794, GO:0044281=Reactome:REACT_111217, GO:0046415=GO_REF:0000019, GO:0003824=GO_REF:0000002, GO:0008645=Reactome:REACT_9441, GO:0015758=Reactome:REACT_212, GO:0035264=GO_REF:0000019, GO:0016773=GO_REF:0000019, GO:0051156=GO_REF:0000019, GO:0008202=GO_REF:0000019, GO:0042632=GO_REF:0000019, GO:0005975=Reactome:REACT_474, GO:0005977=PMID:8211187, GO:0042593=PMID:8211187, GO:0055085=Reactome:REACT_19118, GO:0016020=GO_REF:0000002, GO:0042301=PMID:12093795, GO:0004346=PMID:15661744, GO:0005789=Reactome:REACT_1682, GO:0006641=GO_REF:0000019, GO:0016021=PMID:10318794, GO:0005980=GO_REF:0000019} P35575 Glucose-6-phosphatase protein 20130301 {GO:0010468=IEA, GO:0006094=IMP, GO:0015760=IEA, GO:0030176=TAS, GO:0044281=TAS, GO:0046415=IEA, GO:0003824=IEA, GO:0008645=TAS, GO:0015758=TAS, GO:0035264=IEA, GO:0016773=IEA, GO:0051156=IEA, GO:0008202=IEA, GO:0042632=IEA, GO:0005975=TAS, GO:0005977=TAS, GO:0042593=IMP, GO:0055085=TAS, GO:0016020=IEA, GO:0042301=IMP, GO:0004346=IDA, GO:0005789=TAS, GO:0006641=IEA, GO:0016021=IDA, GO:0005980=IEA} carbohydrate metabolic process, cholesterol homeostasis, gluconeogenesis, glucose 6-phosphate metabolic process, glucose homeostasis, glucose transport, glucose-6-phosphate transport, glycogen catabolic process, glycogen metabolic process, hexose transport, multicellular organism growth, regulation of gene expression, small molecule metabolic process, steroid metabolic process, transmembrane transport, triglyceride metabolic process, urate metabolic process endoplasmic reticulum membrane, integral to endoplasmic reticulum membrane, integral to membrane, membrane catalytic activity, glucose-6-phosphatase activity, phosphate ion binding, phosphotransferase activity, alcohol group as acceptor Human G6PD HPA UniProtKB {GO:0050661=PMID:15858258, GO:0006629=PMID:17361089, GO:0014070=GO_REF:0000019, GO:0006695=PMID:12027950, GO:0045471=GO_REF:0000019, GO:0010734=PMID:17516514, GO:0006749=PMID:17516514, GO:0005634=GO_REF:0000019, GO:0044281=Reactome:REACT_111217, GO:0006098=PMID:2297768, GO:0001816=PMID:17361089, GO:0032094=GO_REF:0000019, GO:0005536=PMID:5643703, GO:0042803=PMID:15858258, GO:0043231=GO_REF:0000052, GO:0005829=PMID:743300, GO:0005737=GO_REF:0000052, GO:0043249=PMID:5643703, GO:0051156=PMID:5643703, GO:0005813=GO_REF:0000052, GO:0005975=Reactome:REACT_474, GO:0009051=PMID:2420826, GO:0046390=PMID:2420826, GO:0019322=PMID:5643703, GO:0006740=PMID:17516514, GO:0004345=PMID:5643703, GO:0009898=PMID:743300, GO:0034599=PMID:17516514, GO:0055114=PMID:2420826} P11413 Glucose-6-phosphate 1-dehydrogenase protein 20101115 {GO:0050661=IDA, GO:0006629=TAS, GO:0014070=IEA, GO:0006695=IMP, GO:0045471=IEA, GO:0010734=IMP, GO:0006749=IMP, GO:0005634=IEA, GO:0044281=TAS, GO:0006098=IDA, GO:0001816=IMP, GO:0032094=IEA, GO:0005536=IMP, GO:0042803=IPI, GO:0043231=IDA, GO:0005829=IDA, GO:0005737=IDA, GO:0043249=IMP, GO:0051156=IMP, GO:0005813=IDA, GO:0005975=TAS, GO:0009051=IMP, GO:0046390=IMP, GO:0019322=IDA, GO:0006740=IMP, GO:0004345=IMP, GO:0009898=IDA, GO:0034599=IMP, GO:0055114=IMP} NADPH regeneration, carbohydrate metabolic process, cellular response to oxidative stress, cholesterol biosynthetic process, cytokine production, erythrocyte maturation, glucose 6-phosphate metabolic process, glutathione metabolic process, lipid metabolic process, negative regulation of protein glutathionylation, oxidation-reduction process, pentose biosynthetic process, pentose-phosphate shunt, pentose-phosphate shunt, oxidative branch, response to ethanol, response to food, response to organic cyclic compound, ribose phosphate biosynthetic process, small molecule metabolic process centrosome, cytoplasm, cytosol, internal side of plasma membrane, intracellular membrane-bounded organelle, nucleus NADP binding, glucose binding, glucose-6-phosphate dehydrogenase activity, protein homodimerization activity Human GAA BHF-UCL UniProtKB {GO:0055010=PMID:10931430, GO:0005765=GO_REF:0000039, GO:0005764=PMID:9505277, GO:0060048=PMID:10931430, GO:0004553=GO_REF:0000002, GO:0046716=GO_REF:0000019, GO:0002086=PMID:16917947, GO:0050884=GO_REF:0000019, GO:0050885=GO_REF:0000019, GO:0009888=GO_REF:0000019, GO:0006006=PMID:9505277, GO:0007626=GO_REF:0000019, GO:0005975=GO_REF:0000002, GO:0000023=PMID:9505277, GO:0003007=GO_REF:0000019, GO:0032450=GO_REF:0000003, GO:0007517=PMID:7717400, GO:0002026=GO_REF:0000019, GO:0030246=GO_REF:0000002, GO:0005985=PMID:9505277, GO:0043181=PMID:10931430, GO:0007040=PMID:7717400, GO:0043587=PMID:10931430, GO:0005980=PMID:9505277, GO:0004558=PMID:9505277} P10253 Lysosomal alpha-glucosidase protein 20071109 {GO:0055010=IMP, GO:0005765=IEA, GO:0005764=IDA, GO:0060048=IMP, GO:0004553=IEA, GO:0046716=IEA, GO:0002086=IMP, GO:0050884=IEA, GO:0050885=IEA, GO:0009888=IEA, GO:0006006=IC, GO:0007626=IEA, GO:0005975=IEA, GO:0000023=IC, GO:0003007=IEA, GO:0032450=IEA, GO:0007517=IMP, GO:0002026=IEA, GO:0030246=IEA, GO:0005985=IC, GO:0043181=IMP, GO:0007040=IMP, GO:0043587=IMP, GO:0005980=IDA, GO:0004558=IDA} carbohydrate metabolic process, cardiac muscle contraction, diaphragm contraction, glucose metabolic process, glycogen catabolic process, heart morphogenesis, locomotory behavior, lysosome organization, maltose metabolic process, muscle cell homeostasis, muscle organ development, neuromuscular process controlling balance, neuromuscular process controlling posture, regulation of the force of heart contraction, sucrose metabolic process, tissue development, tongue morphogenesis, vacuolar sequestering, ventricular cardiac muscle tissue morphogenesis lysosomal membrane, lysosome alpha-glucosidase activity, carbohydrate binding, hydrolase activity, hydrolyzing O-glycosyl compounds, maltose alpha-glucosidase activity Human GAB1 IntAct UniProtKB {GO:0005515=PMID:9658397, GO:0008286=Reactome:REACT_498, GO:0030334=GO_REF:0000019, GO:0048011=Reactome:REACT_11061, GO:0060711=GO_REF:0000019, GO:0008283=PMID:8596638, GO:0048015=Reactome:REACT_12464, GO:0007257=GO_REF:0000019, GO:0005829=Reactome:REACT_147854, GO:0007507=GO_REF:0000019, GO:0005737=GO_REF:0000019, GO:0005543=GO_REF:0000002, GO:0007173=Reactome:REACT_9417, GO:0008544=GO_REF:0000019, GO:0008543=Reactome:REACT_9470, GO:0045087=Reactome:REACT_6802, GO:0005070=PMID:8596638, GO:0004871=GO_REF:0000019, GO:0048008=GO_REF:0000019, GO:0070102=GO_REF:0000019, GO:0006979=GO_REF:0000019} Q13480 GRB2-associated-binding protein 1 protein 20130415 {GO:0005515=IPI, GO:0008286=TAS, GO:0030334=IEA, GO:0048011=TAS, GO:0060711=IEA, GO:0008283=TAS, GO:0048015=TAS, GO:0007257=IEA, GO:0005829=TAS, GO:0007507=IEA, GO:0005737=IEA, GO:0005543=IEA, GO:0007173=TAS, GO:0008544=IEA, GO:0008543=TAS, GO:0045087=TAS, GO:0005070=TAS, GO:0004871=IEA, GO:0048008=IEA, GO:0070102=IEA, GO:0006979=IEA} activation of JUN kinase activity, cell proliferation, epidermal growth factor receptor signaling pathway, epidermis development, fibroblast growth factor receptor signaling pathway, heart development, innate immune response, insulin receptor signaling pathway, interleukin-6-mediated signaling pathway, labyrinthine layer development, neurotrophin TRK receptor signaling pathway, phosphatidylinositol-mediated signaling, platelet-derived growth factor receptor signaling pathway, regulation of cell migration, response to oxidative stress cytoplasm, cytosol SH3/SH2 adaptor activity, phospholipid binding, protein binding, signal transducer activity Human UniProtKB:Q06124 GAB2 GOC UniProtKB {GO:0005515=PMID:21706016, GO:0008284=PMID:19172738, GO:0005886=PMID:19172738, GO:0048015=GO_REF:0000024, GO:0043325=GO_REF:0000024, GO:0030316=PMID:15750601, GO:0005547=GO_REF:0000024, GO:0043306=GO_REF:0000024, GO:0005829=Reactome:REACT_121343, GO:0005737=PMID:19172738, GO:0005543=GO_REF:0000002, GO:0005070=PMID:19641626, GO:0005068=PMID:19172738, GO:0007169=PMID:19172738} Q9UQC2 GRB2-associated-binding protein 2 protein 20130413 {GO:0005515=IPI, GO:0008284=IDA, GO:0005886=IDA, GO:0048015=ISS, GO:0043325=ISS, GO:0030316=IMP, GO:0005547=ISS, GO:0043306=ISS, GO:0005829=TAS, GO:0005737=IDA, GO:0005543=IEA, GO:0005070=RCA, GO:0005068=IDA, GO:0007169=IDA} osteoclast differentiation, phosphatidylinositol-mediated signaling, positive regulation of cell proliferation, positive regulation of mast cell degranulation, transmembrane receptor protein tyrosine kinase signaling pathway cytoplasm, cytosol, plasma membrane SH3/SH2 adaptor activity, phosphatidylinositol-3,4,5-trisphosphate binding, phosphatidylinositol-3,4-bisphosphate binding, phospholipid binding, protein binding, transmembrane receptor protein tyrosine kinase adaptor activity Human GAB3 InterPro UniProtKB {GO:0005543=GO_REF:0000002} Q8WWW8 GRB2-associated-binding protein 3 protein 20130413 {GO:0005543=IEA} phospholipid binding Human InterPro:IPR001849 GABARAP IntAct UniProtKB {GO:0005515=PMID:20562859, GO:0008017=GO_REF:0000019, GO:0048471=GO_REF:0000019, GO:0005776=PMID:19056683, GO:0005794=GO_REF:0000019, GO:0005886=GO_REF:0000019, GO:0005875=GO_REF:0000019, GO:0000421=PMID:15169837, GO:0005874=GO_REF:0000037, GO:0048487=PMID:9892355, GO:0006914=GO_REF:0000037, GO:0006915=PMID:15977068, GO:0000226=GO_REF:0000019, GO:0007268=PMID:9892355, GO:0006605=PMID:9892355, GO:0031410=GO_REF:0000037, GO:0050811=PMID:9892355, GO:0015031=GO_REF:0000019, GO:0015629=GO_REF:0000019, GO:0005764=GO_REF:0000019, GO:0044297=GO_REF:0000019, GO:0005790=GO_REF:0000019, GO:0000139=GO_REF:0000039} O95166 Gamma-aminobutyric acid receptor-associated protein protein 20130415 {GO:0005515=IPI, GO:0008017=IEA, GO:0048471=IEA, GO:0005776=IDA, GO:0005794=IEA, GO:0005886=IEA, GO:0005875=IEA, GO:0000421=IDA, GO:0005874=IEA, GO:0048487=IDA, GO:0006914=IEA, GO:0006915=IDA, GO:0000226=IEA, GO:0007268=TAS, GO:0006605=TAS, GO:0031410=IEA, GO:0050811=IPI, GO:0015031=IEA, GO:0015629=IEA, GO:0005764=IEA, GO:0044297=IEA, GO:0005790=IEA, GO:0000139=IEA} apoptotic process, autophagy, microtubule cytoskeleton organization, protein targeting, protein transport, synaptic transmission Golgi apparatus, Golgi membrane, actin cytoskeleton, autophagic vacuole, autophagic vacuole membrane, cell body, cytoplasmic vesicle, lysosome, microtubule, microtubule associated complex, perinuclear region of cytoplasm, plasma membrane, smooth endoplasmic reticulum GABA receptor binding, beta-tubulin binding, microtubule binding, protein binding Human UniProtKB:Q9Y4P1 GABARAPL1 IntAct UniProtKB {GO:0005622=GO_REF:0000054, GO:0005515=PMID:20562859, GO:0005776=PMID:15292400, GO:0005794=GO_REF:0000039, GO:0005783=GO_REF:0000039, GO:0005874=GO_REF:0000037, GO:0048487=GO_REF:0000024, GO:0006914=GO_REF:0000037, GO:0050811=GO_REF:0000024, GO:0030659=GO_REF:0000039} Q9H0R8 Gamma-aminobutyric acid receptor-associated protein-like 1 protein 20130415 {GO:0005622=IDA, GO:0005515=IPI, GO:0005776=IDA, GO:0005794=IEA, GO:0005783=IEA, GO:0005874=IEA, GO:0048487=ISS, GO:0006914=IEA, GO:0050811=ISS, GO:0030659=IEA} autophagy Golgi apparatus, autophagic vacuole, cytoplasmic vesicle membrane, endoplasmic reticulum, intracellular, microtubule GABA receptor binding, beta-tubulin binding, protein binding Human UniProtKB:Q9Y4P1 GABARAPL2 BHF-UCL UniProtKB {GO:0005515=PMID:21669198, GO:0008017=PMID:11414770, GO:0005776=PMID:21669198, GO:0005794=PMID:11414770, GO:0000421=PMID:15169837, GO:0048487=GO_REF:0000024, GO:0006914=PMID:12507496, GO:0006891=PMID:10747018, GO:0031410=GO_REF:0000037, GO:0050811=PMID:11414770, GO:0032781=PMID:10747018, GO:0015031=GO_REF:0000037, GO:0005829=PMID:11414770, GO:0005622=GO_REF:0000054, GO:0005737=PMID:21669198, GO:0000139=PMID:21669198, GO:0000149=PMID:10747018, GO:0051117=PMID:10747018} P60520 Gamma-aminobutyric acid receptor-associated protein-like 2 protein 20130121 {GO:0005515=IPI, GO:0008017=NAS, GO:0005776=IDA, GO:0005794=ISS, GO:0000421=IDA, GO:0048487=ISS, GO:0006914=NAS, GO:0006891=ISS, GO:0031410=IEA, GO:0050811=NAS, GO:0032781=ISS, GO:0015031=IEA, GO:0005829=ISS, GO:0005622=IDA, GO:0005737=IDA, GO:0000139=IDA, GO:0000149=ISS, GO:0051117=ISS} autophagy, intra-Golgi vesicle-mediated transport, positive regulation of ATPase activity, protein transport Golgi apparatus, Golgi membrane, autophagic vacuole, autophagic vacuole membrane, cytoplasm, cytoplasmic vesicle, cytosol, intracellular ATPase binding, GABA receptor binding, SNARE binding, beta-tubulin binding, microtubule binding, protein binding Human GABBR1 IntAct UniProtKB {GO:0005515=PMID:20195357, GO:0030054=GO_REF:0000037, GO:0005886=Reactome:REACT_25066, GO:0004965=GO_REF:0000002, GO:0007268=Reactome:REACT_13685, GO:0007214=GO_REF:0000019, GO:0005576=GO_REF:0000039, GO:0038037=GO_REF:0000019, GO:0007194=PMID:9069281, GO:0042734=GO_REF:0000019, GO:0005737=GO_REF:0000019, GO:0005887=PMID:9753614, GO:0045211=GO_REF:0000039, GO:0016021=GO_REF:0000038} Q9UBS5 Gamma-aminobutyric acid type B receptor subunit 1 protein 20130415 {GO:0005515=IPI, GO:0030054=IEA, GO:0005886=TAS, GO:0004965=IEA, GO:0007268=TAS, GO:0007214=IEA, GO:0005576=IEA, GO:0038037=IEA, GO:0007194=TAS, GO:0042734=IEA, GO:0005737=IEA, GO:0005887=TAS, GO:0045211=IEA, GO:0016021=IEA} gamma-aminobutyric acid signaling pathway, negative regulation of adenylate cyclase activity, synaptic transmission G-protein coupled receptor dimeric complex, cell junction, cytoplasm, extracellular region, integral to membrane, integral to plasma membrane, plasma membrane, postsynaptic membrane, presynaptic membrane G-protein coupled GABA receptor activity, protein binding Human UniProtKB:P61244 GABBR2 Reactome UniProtKB {GO:0043005=GO_REF:0000019, GO:0005737=GO_REF:0000019, GO:0030054=GO_REF:0000037, GO:0005886=Reactome:REACT_25066, GO:0007186=PMID:9872316, GO:0005887=PMID:10328880, GO:0045211=GO_REF:0000039, GO:0004965=GO_REF:0000019, GO:0007268=Reactome:REACT_13685, GO:0007214=GO_REF:0000019, GO:0007194=PMID:10328880} O75899 Gamma-aminobutyric acid type B receptor subunit 2 protein 20101111 {GO:0043005=IEA, GO:0005737=IEA, GO:0030054=IEA, GO:0005886=TAS, GO:0007186=TAS, GO:0005887=TAS, GO:0045211=IEA, GO:0004965=IEA, GO:0007268=TAS, GO:0007214=IEA, GO:0007194=TAS} G-protein coupled receptor signaling pathway, gamma-aminobutyric acid signaling pathway, negative regulation of adenylate cyclase activity, synaptic transmission cell junction, cytoplasm, integral to plasma membrane, neuron projection, plasma membrane, postsynaptic membrane G-protein coupled GABA receptor activity Human GABPA BHF-UCL UniProtKB {GO:0005515=PMID:10675337, GO:0000790=PMID:22306510, GO:0003700=PMID:8441384, GO:0044212=PMID:9857059, GO:0046982=PMID:9857059, GO:0006366=PMID:8441384, GO:0003713=PMID:8441384, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0000122=GO_REF:0000019, GO:0000978=PMID:22306510, GO:0001228=PMID:22306510, GO:0001701=GO_REF:0000019, GO:0003677=PMID:8441384, GO:0045944=PMID:22306510} Q06546 GA-binding protein alpha chain protein 20121109 {GO:0005515=IPI, GO:0000790=IDA, GO:0003700=TAS, GO:0044212=IDA, GO:0046982=IDA, GO:0006366=TAS, GO:0003713=TAS, GO:0005730=IDA, GO:0005634=IDA, GO:0000122=IEA, GO:0000978=IDA, GO:0001228=IDA, GO:0001701=IEA, GO:0003677=TAS, GO:0045944=IDA} in utero embryonic development, negative regulation of transcription from RNA polymerase II promoter, positive regulation of transcription from RNA polymerase II promoter, transcription from RNA polymerase II promoter nuclear chromatin, nucleolus, nucleus DNA binding, RNA polymerase II core promoter proximal region sequence-specific DNA binding, RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription, protein binding, protein heterodimerization activity, sequence-specific DNA binding transcription factor activity, transcription coactivator activity, transcription regulatory region DNA binding Human GABPB1 IntAct UniProtKB {GO:0005515=PMID:19060904, GO:0003700=PMID:8441384, GO:0006357=PMID:8441384, GO:0046982=PMID:9857059, GO:0044212=PMID:9857059, GO:0045944=PMID:9857059, GO:0005634=PMID:9857059, GO:0006351=GO_REF:0000037} Q06547 GA-binding protein subunit beta-1 protein 20130415 {GO:0005515=IPI, GO:0003700=TAS, GO:0006357=TAS, GO:0046982=IDA, GO:0044212=IDA, GO:0045944=IDA, GO:0005634=IDA, GO:0006351=IEA} positive regulation of transcription from RNA polymerase II promoter, regulation of transcription from RNA polymerase II promoter, transcription, DNA-dependent nucleus protein binding, protein heterodimerization activity, sequence-specific DNA binding transcription factor activity, transcription regulatory region DNA binding Human UniProtKB:Q96M61 GABPB2 MGI UniProtKB {GO:0046982=PMID:9857059, GO:0044212=PMID:9857059, GO:0045944=PMID:9857059, GO:0005634=PMID:9857059, GO:0042803=GO_REF:0000019, GO:0006351=GO_REF:0000037} Q8TAK5 GA-binding protein subunit beta-2 protein 20100615 {GO:0046982=IDA, GO:0044212=IDA, GO:0045944=IDA, GO:0005634=IDA, GO:0042803=IEA, GO:0006351=IEA} positive regulation of transcription from RNA polymerase II promoter, transcription, DNA-dependent nucleus protein heterodimerization activity, protein homodimerization activity, transcription regulatory region DNA binding Human GABRA1 BHF-UCL UniProtKB {GO:0005230=GO_REF:0000002, GO:0030054=GO_REF:0000037, GO:0005886=Reactome:REACT_25130, GO:0004890=GO_REF:0000002, GO:0034707=GO_REF:0000037, GO:0016917=GO_REF:0000024, GO:0007268=Reactome:REACT_13685, GO:0007214=GO_REF:0000002, GO:0055085=Reactome:REACT_15518, GO:0005254=GO_REF:0000037, GO:0034220=Reactome:REACT_25387, GO:0005887=GO_REF:0000024, GO:0008144=GO_REF:0000024, GO:0045211=GO_REF:0000039, GO:0006810=PMID:2465923, GO:0016021=GO_REF:0000002, GO:0051932=GO_REF:0000024} P14867 Gamma-aminobutyric acid receptor subunit alpha-1 protein 20120314 {GO:0005230=IEA, GO:0030054=IEA, GO:0005886=TAS, GO:0004890=IEA, GO:0034707=IEA, GO:0016917=ISS, GO:0007268=TAS, GO:0007214=IEA, GO:0055085=TAS, GO:0005254=IEA, GO:0034220=TAS, GO:0005887=ISS, GO:0008144=ISS, GO:0045211=IEA, GO:0006810=TAS, GO:0016021=IEA, GO:0051932=ISS} gamma-aminobutyric acid signaling pathway, ion transmembrane transport, synaptic transmission, synaptic transmission, GABAergic, transmembrane transport, transport cell junction, chloride channel complex, integral to membrane, integral to plasma membrane, plasma membrane, postsynaptic membrane GABA receptor activity, GABA-A receptor activity, chloride channel activity, drug binding, extracellular ligand-gated ion channel activity Human UniProtKB:P62813 GABRA2 Reactome UniProtKB {GO:0006821=GO_REF:0000002, GO:0030424=GO_REF:0000019, GO:0005230=GO_REF:0000002, GO:0030054=GO_REF:0000037, GO:0005886=Reactome:REACT_25130, GO:0004890=GO_REF:0000002, GO:0034707=GO_REF:0000037, GO:0007268=Reactome:REACT_13685, GO:0007214=PMID:8391122, GO:0055085=Reactome:REACT_15518, GO:0005254=GO_REF:0000037, GO:0034220=Reactome:REACT_25387, GO:0030285=PMID:8391122, GO:0001505=PMID:8391122, GO:0045211=GO_REF:0000039, GO:0008503=PMID:8391122, GO:0006836=PMID:8391122, GO:0016021=GO_REF:0000002, GO:0006811=GO_REF:0000002} P47869 Gamma-aminobutyric acid receptor subunit alpha-2 protein 20130301 {GO:0006821=IEA, GO:0030424=IEA, GO:0005230=IEA, GO:0030054=IEA, GO:0005886=TAS, GO:0004890=IEA, GO:0034707=IEA, GO:0007268=TAS, GO:0007214=IMP, GO:0055085=TAS, GO:0005254=IEA, GO:0034220=TAS, GO:0030285=IDA, GO:0001505=IMP, GO:0045211=IEA, GO:0008503=IMP, GO:0006836=IMP, GO:0016021=IEA, GO:0006811=IEA} chloride transport, gamma-aminobutyric acid signaling pathway, ion transmembrane transport, ion transport, neurotransmitter transport, regulation of neurotransmitter levels, synaptic transmission, transmembrane transport axon, cell junction, chloride channel complex, integral to membrane, integral to synaptic vesicle membrane, plasma membrane, postsynaptic membrane GABA-A receptor activity, benzodiazepine receptor activity, chloride channel activity, extracellular ligand-gated ion channel activity Human GABRA3 Reactome UniProtKB {GO:0005230=GO_REF:0000002, GO:0030054=GO_REF:0000037, GO:0005886=Reactome:REACT_25130, GO:0004890=GO_REF:0000002, GO:0034707=GO_REF:0000037, GO:0007268=Reactome:REACT_13685, GO:0007214=GO_REF:0000002, GO:0055085=Reactome:REACT_15518, GO:0005254=GO_REF:0000037, GO:0034220=Reactome:REACT_25387, GO:0005887=PMID:8391122, GO:0045211=GO_REF:0000039, GO:0006810=PMID:8391122, GO:0008503=PMID:8391122, GO:0016021=GO_REF:0000002} P34903 Gamma-aminobutyric acid receptor subunit alpha-3 protein 20130301 {GO:0005230=IEA, GO:0030054=IEA, GO:0005886=TAS, GO:0004890=IEA, GO:0034707=IEA, GO:0007268=TAS, GO:0007214=IEA, GO:0055085=TAS, GO:0005254=IEA, GO:0034220=TAS, GO:0005887=TAS, GO:0045211=IEA, GO:0006810=TAS, GO:0008503=TAS, GO:0016021=IEA} gamma-aminobutyric acid signaling pathway, ion transmembrane transport, synaptic transmission, transmembrane transport, transport cell junction, chloride channel complex, integral to membrane, integral to plasma membrane, plasma membrane, postsynaptic membrane GABA-A receptor activity, benzodiazepine receptor activity, chloride channel activity, extracellular ligand-gated ion channel activity Human GABRA4 Reactome UniProtKB {GO:0005230=GO_REF:0000002, GO:0030054=GO_REF:0000037, GO:0005886=Reactome:REACT_25130, GO:0004890=GO_REF:0000002, GO:0034707=GO_REF:0000037, GO:0007268=Reactome:REACT_13685, GO:0007214=GO_REF:0000002, GO:0007417=GO_REF:0000019, GO:0055085=Reactome:REACT_15518, GO:0005254=GO_REF:0000037, GO:0034220=Reactome:REACT_25387, GO:0005887=PMID:8719416, GO:0045211=GO_REF:0000039, GO:0006810=PMID:8719416, GO:0008503=PMID:8719416, GO:2001023=GO_REF:0000019} P48169 Gamma-aminobutyric acid receptor subunit alpha-4 protein 20130301 {GO:0005230=IEA, GO:0030054=IEA, GO:0005886=TAS, GO:0004890=IEA, GO:0034707=IEA, GO:0007268=TAS, GO:0007214=IEA, GO:0007417=IEA, GO:0055085=TAS, GO:0005254=IEA, GO:0034220=TAS, GO:0005887=TAS, GO:0045211=IEA, GO:0006810=TAS, GO:0008503=TAS, GO:2001023=IEA} central nervous system development, gamma-aminobutyric acid signaling pathway, ion transmembrane transport, regulation of response to drug, synaptic transmission, transmembrane transport, transport cell junction, chloride channel complex, integral to plasma membrane, plasma membrane, postsynaptic membrane GABA-A receptor activity, benzodiazepine receptor activity, chloride channel activity, extracellular ligand-gated ion channel activity Human GABRA5 Reactome UniProtKB {GO:0006821=GO_REF:0000002, GO:0005215=PMID:1321750, GO:0005230=GO_REF:0000002, GO:0030054=GO_REF:0000037, GO:0005886=Reactome:REACT_25130, GO:0007605=GO_REF:0000019, GO:0007268=Reactome:REACT_13685, GO:0050811=GO_REF:0000019, GO:0005254=GO_REF:0000037, GO:0030425=GO_REF:0000019, GO:0034220=Reactome:REACT_25387, GO:0045211=GO_REF:0000039, GO:0006810=PMID:1321750, GO:0090102=GO_REF:0000019, GO:0001662=GO_REF:0000019, GO:0004872=PMID:1321750, GO:0008306=GO_REF:0000019, GO:0004890=GO_REF:0000019, GO:0034707=GO_REF:0000037, GO:0060119=GO_REF:0000019, GO:0007214=GO_REF:0000002, GO:0055085=Reactome:REACT_15518, GO:0032809=GO_REF:0000019, GO:0043235=GO_REF:0000019, GO:0060384=GO_REF:0000019, GO:0007165=PMID:1321750, GO:0007420=GO_REF:0000019, GO:0005887=PMID:1321750, GO:0016021=GO_REF:0000002, GO:0005216=GO_REF:0000002} P31644 Gamma-aminobutyric acid receptor subunit alpha-5 protein 20130301 {GO:0006821=IEA, GO:0005215=TAS, GO:0005230=IEA, GO:0030054=IEA, GO:0005886=TAS, GO:0007605=IEA, GO:0007268=TAS, GO:0050811=IEA, GO:0005254=IEA, GO:0030425=IEA, GO:0034220=TAS, GO:0045211=IEA, GO:0006810=TAS, GO:0090102=IEA, GO:0001662=IEA, GO:0004872=TAS, GO:0008306=IEA, GO:0004890=IEA, GO:0034707=IEA, GO:0060119=IEA, GO:0007214=IEA, GO:0055085=TAS, GO:0032809=IEA, GO:0043235=IEA, GO:0060384=IEA, GO:0007165=TAS, GO:0007420=IEA, GO:0005887=TAS, GO:0016021=IEA, GO:0005216=IEA} associative learning, behavioral fear response, brain development, chloride transport, cochlea development, gamma-aminobutyric acid signaling pathway, inner ear receptor cell development, innervation, ion transmembrane transport, sensory perception of sound, signal transduction, synaptic transmission, transmembrane transport, transport cell junction, chloride channel complex, dendrite, integral to membrane, integral to plasma membrane, neuronal cell body membrane, plasma membrane, postsynaptic membrane, receptor complex GABA receptor binding, GABA-A receptor activity, chloride channel activity, extracellular ligand-gated ion channel activity, ion channel activity, receptor activity, transporter activity Human GABRA6 Reactome UniProtKB {GO:0006821=GO_REF:0000002, GO:0005230=GO_REF:0000002, GO:0030054=GO_REF:0000037, GO:0005886=Reactome:REACT_25130, GO:0004890=GO_REF:0000002, GO:0034707=GO_REF:0000037, GO:0007268=Reactome:REACT_13685, GO:0007214=GO_REF:0000002, GO:0055085=Reactome:REACT_15518, GO:0005254=GO_REF:0000037, GO:0007165=PMID:8632757, GO:0034220=Reactome:REACT_25387, GO:0005887=PMID:8632757, GO:0045211=GO_REF:0000039, GO:0008503=PMID:8632757, GO:0006810=PMID:8632757, GO:0016021=GO_REF:0000002} Q16445 Gamma-aminobutyric acid receptor subunit alpha-6 protein 20130301 {GO:0006821=IEA, GO:0005230=IEA, GO:0030054=IEA, GO:0005886=TAS, GO:0004890=IEA, GO:0034707=IEA, GO:0007268=TAS, GO:0007214=IEA, GO:0055085=TAS, GO:0005254=IEA, GO:0007165=TAS, GO:0034220=TAS, GO:0005887=TAS, GO:0045211=IEA, GO:0008503=TAS, GO:0006810=TAS, GO:0016021=IEA} chloride transport, gamma-aminobutyric acid signaling pathway, ion transmembrane transport, signal transduction, synaptic transmission, transmembrane transport, transport cell junction, chloride channel complex, integral to membrane, integral to plasma membrane, plasma membrane, postsynaptic membrane GABA-A receptor activity, benzodiazepine receptor activity, chloride channel activity, extracellular ligand-gated ion channel activity Human GABRB1 Reactome UniProtKB {GO:0005230=GO_REF:0000002, GO:0030054=GO_REF:0000037, GO:0005886=Reactome:REACT_25130, GO:0007268=Reactome:REACT_13685, GO:0042698=GO_REF:0000019, GO:0005635=GO_REF:0000019, GO:0050811=GO_REF:0000019, GO:0005254=GO_REF:0000037, GO:0030425=GO_REF:0000019, GO:0005253=GO_REF:0000019, GO:0005737=GO_REF:0000019, GO:0034220=Reactome:REACT_25387, GO:0045211=GO_REF:0000039, GO:0006810=PMID:2465923, GO:0006811=GO_REF:0000002, GO:0004890=GO_REF:0000019, GO:0021954=GO_REF:0000019, GO:0034707=GO_REF:0000037, GO:0009636=GO_REF:0000019, GO:0055085=Reactome:REACT_15518, GO:0043235=GO_REF:0000019, GO:0007165=PMID:2465923, GO:0005887=PMID:2465923, GO:0032570=GO_REF:0000019, GO:0016021=GO_REF:0000038} P18505 Gamma-aminobutyric acid receptor subunit beta-1 protein 20130301 {GO:0005230=IEA, GO:0030054=IEA, GO:0005886=TAS, GO:0007268=TAS, GO:0042698=IEA, GO:0005635=IEA, GO:0050811=IEA, GO:0005254=IEA, GO:0030425=IEA, GO:0005253=IEA, GO:0005737=IEA, GO:0034220=TAS, GO:0045211=IEA, GO:0006810=TAS, GO:0006811=IEA, GO:0004890=IEA, GO:0021954=IEA, GO:0034707=IEA, GO:0009636=IEA, GO:0055085=TAS, GO:0043235=IEA, GO:0007165=TAS, GO:0005887=TAS, GO:0032570=IEA, GO:0016021=IEA} central nervous system neuron development, ion transmembrane transport, ion transport, ovulation cycle, response to progesterone stimulus, response to toxic substance, signal transduction, synaptic transmission, transmembrane transport, transport cell junction, chloride channel complex, cytoplasm, dendrite, integral to membrane, integral to plasma membrane, nuclear envelope, plasma membrane, postsynaptic membrane, receptor complex GABA receptor binding, GABA-A receptor activity, anion channel activity, chloride channel activity, extracellular ligand-gated ion channel activity Human GABRB2 BHF-UCL UniProtKB {GO:0005230=GO_REF:0000002, GO:0030054=GO_REF:0000037, GO:0005886=Reactome:REACT_25130, GO:0004890=GO_REF:0000024, GO:0005237=GO_REF:0000019, GO:0007605=GO_REF:0000019, GO:0034707=GO_REF:0000037, GO:0007268=Reactome:REACT_13685, GO:0060119=GO_REF:0000019, GO:0007214=PMID:8264558, GO:0055085=Reactome:REACT_15518, GO:0005254=GO_REF:0000037, GO:0005829=GO_REF:0000019, GO:0060384=GO_REF:0000019, GO:0034220=Reactome:REACT_25387, GO:0005887=PMID:8264558, GO:0045211=GO_REF:0000039, GO:0006810=PMID:8264558, GO:0090102=GO_REF:0000019, GO:0016021=GO_REF:0000038, GO:0051932=GO_REF:0000024} P47870 Gamma-aminobutyric acid receptor subunit beta-2 protein 20120314 {GO:0005230=IEA, GO:0030054=IEA, GO:0005886=TAS, GO:0004890=ISS, GO:0005237=IEA, GO:0007605=IEA, GO:0034707=IEA, GO:0007268=TAS, GO:0060119=IEA, GO:0007214=TAS, GO:0055085=TAS, GO:0005254=IEA, GO:0005829=IEA, GO:0060384=IEA, GO:0034220=TAS, GO:0005887=TAS, GO:0045211=IEA, GO:0006810=TAS, GO:0090102=IEA, GO:0016021=IEA, GO:0051932=ISS} cochlea development, gamma-aminobutyric acid signaling pathway, inner ear receptor cell development, innervation, ion transmembrane transport, sensory perception of sound, synaptic transmission, synaptic transmission, GABAergic, transmembrane transport, transport cell junction, chloride channel complex, cytosol, integral to membrane, integral to plasma membrane, plasma membrane, postsynaptic membrane GABA-A receptor activity, chloride channel activity, extracellular ligand-gated ion channel activity, inhibitory extracellular ligand-gated ion channel activity Human UniProtKB:P63138 GABRB3 Reactome UniProtKB {GO:0005230=GO_REF:0000002, GO:0030054=GO_REF:0000037, GO:0005886=Reactome:REACT_25130, GO:0004890=GO_REF:0000002, GO:0007605=GO_REF:0000019, GO:0034707=GO_REF:0000037, GO:0007268=Reactome:REACT_13685, GO:0060119=GO_REF:0000019, GO:0055085=Reactome:REACT_15518, GO:0005254=GO_REF:0000037, GO:0060384=GO_REF:0000019, GO:0007165=PMID:1664410, GO:0034220=Reactome:REACT_25387, GO:0005887=PMID:1664410, GO:0045211=GO_REF:0000039, GO:0006810=PMID:1664410, GO:0090102=GO_REF:0000019, GO:0016021=GO_REF:0000002, GO:0006811=GO_REF:0000002} P28472 Gamma-aminobutyric acid receptor subunit beta-3 protein 20130301 {GO:0005230=IEA, GO:0030054=IEA, GO:0005886=TAS, GO:0004890=IEA, GO:0007605=IEA, GO:0034707=IEA, GO:0007268=TAS, GO:0060119=IEA, GO:0055085=TAS, GO:0005254=IEA, GO:0060384=IEA, GO:0007165=TAS, GO:0034220=TAS, GO:0005887=TAS, GO:0045211=IEA, GO:0006810=TAS, GO:0090102=IEA, GO:0016021=IEA, GO:0006811=IEA} cochlea development, inner ear receptor cell development, innervation, ion transmembrane transport, ion transport, sensory perception of sound, signal transduction, synaptic transmission, transmembrane transport, transport cell junction, chloride channel complex, integral to membrane, integral to plasma membrane, plasma membrane, postsynaptic membrane GABA-A receptor activity, chloride channel activity, extracellular ligand-gated ion channel activity Human GABRD PINC UniProtKB {GO:0007165=PMID:2176788, GO:0005230=GO_REF:0000002, GO:0030054=GO_REF:0000037, GO:0005887=PMID:2176788, GO:0004890=GO_REF:0000019, GO:0045211=GO_REF:0000039, GO:0006810=PMID:2176788, GO:0034707=GO_REF:0000037, GO:0007268=GO_REF:0000019, GO:0005254=GO_REF:0000037} O14764 Gamma-aminobutyric acid receptor subunit delta protein 20030904 {GO:0007165=TAS, GO:0005230=IEA, GO:0030054=IEA, GO:0005887=TAS, GO:0004890=IEA, GO:0045211=IEA, GO:0006810=TAS, GO:0034707=IEA, GO:0007268=IEA, GO:0005254=IEA} signal transduction, synaptic transmission, transport cell junction, chloride channel complex, integral to plasma membrane, postsynaptic membrane GABA-A receptor activity, chloride channel activity, extracellular ligand-gated ion channel activity Human GABRG1 UniProtKB UniProtKB {GO:0043235=GO_REF:0000019, GO:0005230=GO_REF:0000002, GO:0030054=GO_REF:0000037, GO:0005886=GO_REF:0000039, GO:0004890=GO_REF:0000019, GO:0045211=GO_REF:0000039, GO:0034707=GO_REF:0000037, GO:0007268=GO_REF:0000019, GO:0007214=GO_REF:0000002, GO:0050811=GO_REF:0000019, GO:0005254=GO_REF:0000037} Q8N1C3 Gamma-aminobutyric acid receptor subunit gamma-1 protein 20130413 {GO:0043235=IEA, GO:0005230=IEA, GO:0030054=IEA, GO:0005886=IEA, GO:0004890=IEA, GO:0045211=IEA, GO:0034707=IEA, GO:0007268=IEA, GO:0007214=IEA, GO:0050811=IEA, GO:0005254=IEA} gamma-aminobutyric acid signaling pathway, synaptic transmission cell junction, chloride channel complex, plasma membrane, postsynaptic membrane, receptor complex GABA receptor binding, GABA-A receptor activity, chloride channel activity, extracellular ligand-gated ion channel activity Human UniProtKB-SubCell:SL-0219 GABRG2 BHF-UCL UniProtKB {GO:0005515=PMID:9892355, GO:0006821=GO_REF:0000002, GO:0030424=GO_REF:0000019, GO:0005230=GO_REF:0000002, GO:0030054=GO_REF:0000037, GO:0005886=Reactome:REACT_25130, GO:0004890=GO_REF:0000002, GO:0034707=GO_REF:0000037, GO:0007268=Reactome:REACT_13685, GO:0060077=GO_REF:0000019, GO:0007214=GO_REF:0000002, GO:0009791=GO_REF:0000019, GO:0055085=Reactome:REACT_15518, GO:0005254=GO_REF:0000037, GO:0005737=GO_REF:0000019, GO:0034220=Reactome:REACT_25387, GO:0032590=GO_REF:0000024, GO:0005887=PMID:2538761, GO:0045211=GO_REF:0000039, GO:0006810=PMID:2538761, GO:0008503=PMID:2538761, GO:0030534=GO_REF:0000019, GO:0016021=GO_REF:0000038, GO:0051932=GO_REF:0000024} P18507 Gamma-aminobutyric acid receptor subunit gamma-2 protein 20120314 {GO:0005515=IPI, GO:0006821=IEA, GO:0030424=IEA, GO:0005230=IEA, GO:0030054=IEA, GO:0005886=TAS, GO:0004890=IEA, GO:0034707=IEA, GO:0007268=TAS, GO:0060077=IEA, GO:0007214=IEA, GO:0009791=IEA, GO:0055085=TAS, GO:0005254=IEA, GO:0005737=IEA, GO:0034220=TAS, GO:0032590=ISS, GO:0005887=TAS, GO:0045211=IEA, GO:0006810=TAS, GO:0008503=TAS, GO:0030534=IEA, GO:0016021=IEA, GO:0051932=ISS} adult behavior, chloride transport, gamma-aminobutyric acid signaling pathway, ion transmembrane transport, post-embryonic development, synaptic transmission, synaptic transmission, GABAergic, transmembrane transport, transport axon, cell junction, chloride channel complex, cytoplasm, dendrite membrane, inhibitory synapse, integral to membrane, integral to plasma membrane, plasma membrane, postsynaptic membrane GABA-A receptor activity, benzodiazepine receptor activity, chloride channel activity, extracellular ligand-gated ion channel activity, protein binding Human UniProtKB:P18508 GABRG3 Reactome UniProtKB {GO:0006821=GO_REF:0000002, GO:0005230=GO_REF:0000029, GO:0030054=GO_REF:0000037, GO:0005886=Reactome:REACT_25130, GO:0004890=GO_REF:0000019, GO:0042493=GO_REF:0000019, GO:0034707=GO_REF:0000037, GO:0007268=Reactome:REACT_13685, GO:0007214=GO_REF:0000002, GO:0055085=Reactome:REACT_15518, GO:0005254=GO_REF:0000019, GO:0034220=Reactome:REACT_25387, GO:0045211=GO_REF:0000039, GO:0016021=GO_REF:0000029} Q99928 Gamma-aminobutyric acid receptor subunit gamma-3 protein 20130301 {GO:0006821=IEA, GO:0005230=NAS, GO:0030054=IEA, GO:0005886=TAS, GO:0004890=IEA, GO:0042493=IEA, GO:0034707=IEA, GO:0007268=TAS, GO:0007214=IEA, GO:0055085=TAS, GO:0005254=IEA, GO:0034220=TAS, GO:0045211=IEA, GO:0016021=NAS} chloride transport, gamma-aminobutyric acid signaling pathway, ion transmembrane transport, response to drug, synaptic transmission, transmembrane transport cell junction, chloride channel complex, integral to membrane, plasma membrane, postsynaptic membrane GABA-A receptor activity, chloride channel activity, extracellular ligand-gated ion channel activity Human GABRQ GOC UniProtKB {GO:0007165=PMID:10449790, GO:0005230=GO_REF:0000002, GO:0030054=GO_REF:0000037, GO:0005887=PMID:10449790, GO:0004890=GO_REF:0000002, GO:0045211=GO_REF:0000039, GO:0005326=PMID:10449790, GO:0006836=PMID:10449790, GO:0034707=GO_REF:0000037, GO:0005254=GO_REF:0000037, GO:0004888=PMID:10449790} Q9UN88 Gamma-aminobutyric acid receptor subunit theta protein 20130413 {GO:0007165=TAS, GO:0005230=IEA, GO:0030054=IEA, GO:0005887=TAS, GO:0004890=IEA, GO:0045211=IEA, GO:0005326=TAS, GO:0006836=TAS, GO:0034707=IEA, GO:0005254=IEA, GO:0004888=TAS} neurotransmitter transport, signal transduction cell junction, chloride channel complex, integral to plasma membrane, postsynaptic membrane GABA-A receptor activity, chloride channel activity, extracellular ligand-gated ion channel activity, neurotransmitter transporter activity, transmembrane signaling receptor activity Human GABRR1 Reactome UniProtKB {GO:0005230=GO_REF:0000002, GO:0030054=GO_REF:0000037, GO:0005886=Reactome:REACT_25391, GO:0004890=GO_REF:0000002, GO:0034707=GO_REF:0000037, GO:0007268=Reactome:REACT_13685, GO:0007214=PMID:10779366, GO:0055085=Reactome:REACT_15518, GO:0005254=GO_REF:0000037, GO:0034220=Reactome:REACT_25387, GO:0005887=PMID:10779366, GO:0045211=GO_REF:0000039, GO:0006810=PMID:1849271, GO:0016021=GO_REF:0000038} P24046 Gamma-aminobutyric acid receptor subunit rho-1 protein 20130301 {GO:0005230=IEA, GO:0030054=IEA, GO:0005886=TAS, GO:0004890=IEA, GO:0034707=IEA, GO:0007268=TAS, GO:0007214=TAS, GO:0055085=TAS, GO:0005254=IEA, GO:0034220=TAS, GO:0005887=TAS, GO:0045211=IEA, GO:0006810=TAS, GO:0016021=IEA} gamma-aminobutyric acid signaling pathway, ion transmembrane transport, synaptic transmission, transmembrane transport, transport cell junction, chloride channel complex, integral to membrane, integral to plasma membrane, plasma membrane, postsynaptic membrane GABA-A receptor activity, chloride channel activity, extracellular ligand-gated ion channel activity Human GABRR2 Reactome UniProtKB {GO:0005230=GO_REF:0000002, GO:0030054=GO_REF:0000037, GO:0005886=Reactome:REACT_25391, GO:0004890=GO_REF:0000019, GO:0019904=GO_REF:0000019, GO:0034707=GO_REF:0000037, GO:0007268=Reactome:REACT_13685, GO:0007214=GO_REF:0000019, GO:0055085=Reactome:REACT_15518, GO:0005254=GO_REF:0000037, GO:0007165=PMID:1315307, GO:0034220=Reactome:REACT_25387, GO:0005887=PMID:1315307, GO:0045211=GO_REF:0000039, GO:0006810=PMID:1315307, GO:0007601=GO_REF:0000019} P28476 Gamma-aminobutyric acid receptor subunit rho-2 protein 20130301 {GO:0005230=IEA, GO:0030054=IEA, GO:0005886=TAS, GO:0004890=IEA, GO:0019904=IEA, GO:0034707=IEA, GO:0007268=TAS, GO:0007214=IEA, GO:0055085=TAS, GO:0005254=IEA, GO:0007165=TAS, GO:0034220=TAS, GO:0005887=TAS, GO:0045211=IEA, GO:0006810=TAS, GO:0007601=IEA} gamma-aminobutyric acid signaling pathway, ion transmembrane transport, signal transduction, synaptic transmission, transmembrane transport, transport, visual perception cell junction, chloride channel complex, integral to plasma membrane, plasma membrane, postsynaptic membrane GABA-A receptor activity, chloride channel activity, extracellular ligand-gated ion channel activity, protein domain specific binding Human GABRR3 Reactome UniProtKB {GO:0005230=GO_REF:0000002, GO:0030054=GO_REF:0000037, GO:0005886=Reactome:REACT_25391, GO:0004890=PMID:10542332, GO:0019904=GO_REF:0000019, GO:0034707=GO_REF:0000037, GO:0007268=Reactome:REACT_13685, GO:0007214=PMID:10542332, GO:0005575=GO_REF:0000015, GO:0005254=GO_REF:0000037, GO:0055085=Reactome:REACT_15518, GO:0034220=Reactome:REACT_25387, GO:0045211=GO_REF:0000039} A8MPY1 Gamma-aminobutyric acid receptor subunit rho-3 protein 20130301 {GO:0005230=IEA, GO:0030054=IEA, GO:0005886=TAS, GO:0004890=NAS, GO:0019904=IEA, GO:0034707=IEA, GO:0007268=TAS, GO:0007214=NAS, GO:0005575=ND, GO:0005254=IEA, GO:0055085=TAS, GO:0034220=TAS, GO:0045211=IEA} gamma-aminobutyric acid signaling pathway, ion transmembrane transport, synaptic transmission, transmembrane transport cell junction, cellular_component, chloride channel complex, plasma membrane, postsynaptic membrane GABA-A receptor activity, chloride channel activity, extracellular ligand-gated ion channel activity, protein domain specific binding Human GAD1 IntAct UniProtKB {GO:0012506=PMID:10671565, GO:0005515=PMID:17474147, GO:0005886=Reactome:REACT_23813, GO:0046982=GO_REF:0000019, GO:0042493=GO_REF:0000019, GO:0006538=PMID:10671565, GO:0007268=Reactome:REACT_13685, GO:0018352=PMID:10671565, GO:0007269=Reactome:REACT_13723, GO:0005622=PMID:10671565, GO:0004351=PMID:10671565, GO:0047485=GO_REF:0000019, GO:0030170=GO_REF:0000002, GO:0016831=GO_REF:0000002, GO:0061202=Reactome:REACT_23973, GO:0016595=GO_REF:0000019, GO:0042136=GO_REF:0000037, GO:0006540=PMID:1549570, GO:0009449=GO_REF:0000019, GO:0019752=GO_REF:0000002} Q99259 Glutamate decarboxylase 1 protein 20130415 {GO:0012506=NAS, GO:0005515=IPI, GO:0005886=TAS, GO:0046982=IEA, GO:0042493=IEA, GO:0006538=TAS, GO:0007268=TAS, GO:0018352=TAS, GO:0007269=TAS, GO:0005622=IDA, GO:0004351=IDA, GO:0047485=IEA, GO:0030170=IEA, GO:0016831=IEA, GO:0061202=TAS, GO:0016595=IEA, GO:0042136=IEA, GO:0006540=TAS, GO:0009449=IEA, GO:0019752=IEA} carboxylic acid metabolic process, gamma-aminobutyric acid biosynthetic process, glutamate catabolic process, glutamate decarboxylation to succinate, neurotransmitter biosynthetic process, neurotransmitter secretion, protein-pyridoxal-5-phosphate linkage, response to drug, synaptic transmission clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane, intracellular, plasma membrane, vesicle membrane carboxy-lyase activity, glutamate binding, glutamate decarboxylase activity, protein N-terminus binding, protein binding, protein heterodimerization activity, pyridoxal phosphate binding Human UniProtKB:P16333 GAD2 InterPro UniProtKB {GO:0005515=PMID:10671565, GO:0030424=GO_REF:0000019, GO:0048471=GO_REF:0000019, GO:0030054=GO_REF:0000037, GO:0005886=Reactome:REACT_23813, GO:0046982=GO_REF:0000019, GO:0042493=GO_REF:0000019, GO:0007268=Reactome:REACT_13685, GO:0031225=GO_REF:0000019, GO:0007269=Reactome:REACT_13723, GO:0005829=GO_REF:0000039, GO:0042734=GO_REF:0000039, GO:0004351=GO_REF:0000003, GO:0000139=GO_REF:0000039, GO:0030170=GO_REF:0000002, GO:0016831=GO_REF:0000002, GO:0030672=GO_REF:0000019, GO:0061202=Reactome:REACT_23973, GO:0042136=GO_REF:0000037, GO:0016595=GO_REF:0000019, GO:0006540=GO_REF:0000019, GO:0019752=GO_REF:0000002} Q5VZ29 Glutamate decarboxylase 2 protein 20130413 {GO:0005515=IPI, GO:0030424=IEA, GO:0048471=IEA, GO:0030054=IEA, GO:0005886=TAS, GO:0046982=IEA, GO:0042493=IEA, GO:0007268=TAS, GO:0031225=IEA, GO:0007269=TAS, GO:0005829=IEA, GO:0042734=IEA, GO:0004351=IEA, GO:0000139=IEA, GO:0030170=IEA, GO:0016831=IEA, GO:0030672=IEA, GO:0061202=TAS, GO:0042136=IEA, GO:0016595=IEA, GO:0006540=IEA, GO:0019752=IEA} carboxylic acid metabolic process, glutamate decarboxylation to succinate, neurotransmitter biosynthetic process, neurotransmitter secretion, response to drug, synaptic transmission Golgi membrane, anchored to membrane, axon, cell junction, clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane, cytosol, perinuclear region of cytoplasm, plasma membrane, presynaptic membrane, synaptic vesicle membrane carboxy-lyase activity, glutamate binding, glutamate decarboxylase activity, protein binding, protein heterodimerization activity, pyridoxal phosphate binding Human InterPro:IPR002129|InterPro:IPR015421 GADD45A BHF-UCL UniProtKB {GO:0042770=PMID:20160708, GO:0005515=PMID:21988832, GO:0006281=PMID:7973727, GO:0007098=GO_REF:0000019, GO:0006915=PMID:10828065, GO:0005634=GO_REF:0000054, GO:0007050=GO_REF:0000037, GO:0000079=PMID:10747892, GO:0006469=GO_REF:0000019, GO:0071260=PMID:19593445, GO:2000379=PMID:20160708, GO:0071479=PMID:20160708} P24522 Growth arrest and DNA damage-inducible protein GADD45 alpha protein 20101021 {GO:0042770=IMP, GO:0005515=IPI, GO:0006281=TAS, GO:0007098=IEA, GO:0006915=TAS, GO:0005634=IDA, GO:0007050=IEA, GO:0000079=TAS, GO:0006469=IEA, GO:0071260=IEP, GO:2000379=IMP, GO:0071479=IMP} DNA repair, apoptotic process, cell cycle arrest, cellular response to ionizing radiation, cellular response to mechanical stimulus, centrosome cycle, negative regulation of protein kinase activity, positive regulation of reactive oxygen species metabolic process, regulation of cyclin-dependent protein serine/threonine kinase activity, signal transduction in response to DNA damage nucleus protein binding Human GADD45B ENSEMBL UniProtKB {GO:0000186=GO_REF:0000019, GO:0000185=PMID:9827804, GO:0051726=GO_REF:0000019, GO:0006950=GO_REF:0000002, GO:0006915=GO_REF:0000037, GO:0007275=GO_REF:0000037, GO:0005634=GO_REF:0000002, GO:0006469=GO_REF:0000019, GO:0030154=GO_REF:0000037} Q6IX74 Growth arrest and DNA-damage-inducible beta protein 20130413 {GO:0000186=IEA, GO:0000185=TAS, GO:0051726=IEA, GO:0006950=IEA, GO:0006915=IEA, GO:0007275=IEA, GO:0005634=IEA, GO:0006469=IEA, GO:0030154=IEA} activation of MAPKK activity, activation of MAPKKK activity, apoptotic process, cell differentiation, multicellular organismal development, negative regulation of protein kinase activity, regulation of cell cycle, response to stress nucleus Human Ensembl:ENSMUSP00000015456 GADD45G ENSEMBL UniProtKB {GO:0005515=PMID:15383276, GO:0000186=GO_REF:0000019, GO:0006281=PMID:9827804, GO:0000185=PMID:9827804, GO:0006950=GO_REF:0000002, GO:0051726=GO_REF:0000019, GO:0006915=GO_REF:0000037, GO:0007275=GO_REF:0000037, GO:0005634=GO_REF:0000002, GO:0006469=GO_REF:0000019, GO:0030154=GO_REF:0000037} Q5VZ88 Growth arrest and DNA damage-inducible protein GADD45 gamma protein 20130413 {GO:0005515=IPI, GO:0000186=IEA, GO:0006281=TAS, GO:0000185=TAS, GO:0006950=IEA, GO:0051726=IEA, GO:0006915=IEA, GO:0007275=IEA, GO:0005634=IEA, GO:0006469=IEA, GO:0030154=IEA} DNA repair, activation of MAPKK activity, activation of MAPKKK activity, apoptotic process, cell differentiation, multicellular organismal development, negative regulation of protein kinase activity, regulation of cell cycle, response to stress nucleus protein binding Human Ensembl:ENSMUSP00000021903 GADD45GIP1 IntAct UniProtKB {GO:0005515=PMID:12716909, GO:0005739=GO_REF:0000039, GO:0007049=GO_REF:0000037, GO:0019048=GO_REF:0000037, GO:0005634=GO_REF:0000039} Q8TAE8 Growth arrest and DNA damage-inducible proteins-interacting protein 1 protein 20130415 {GO:0005515=IPI, GO:0005739=IEA, GO:0007049=IEA, GO:0019048=IEA, GO:0005634=IEA} cell cycle, virus-host interaction mitochondrion, nucleus protein binding Human UniProtKB:P24522 GAGE1 PINC UniProtKB {GO:0006968=PMID:7544395} Q13065 G antigen 1 protein 20030904 {GO:0006968=TAS} cellular defense response Human GAGE12I null null {} null null null null {} null null null GAGE2E null null {} null null null null {} null null null GAGE5 null null {} null null null null {} null null null GAK HPA UniProtKB {GO:0005515=PMID:22645275, GO:0005737=GO_REF:0000052, GO:0048471=GO_REF:0000039, GO:0007049=GO_REF:0000037, GO:0005794=GO_REF:0000052, GO:0004672=GO_REF:0000002, GO:0004674=GO_REF:0000037, GO:0016301=GO_REF:0000038, GO:0005925=GO_REF:0000039, GO:0005524=GO_REF:0000037, GO:0016772=GO_REF:0000002} O14976 Cyclin-G-associated kinase protein 20101115 {GO:0005515=IPI, GO:0005737=IDA, GO:0048471=IEA, GO:0007049=IEA, GO:0005794=IDA, GO:0004672=IEA, GO:0004674=IEA, GO:0016301=IEA, GO:0005925=IEA, GO:0005524=IEA, GO:0016772=IEA} cell cycle Golgi apparatus, cytoplasm, focal adhesion, perinuclear region of cytoplasm ATP binding, kinase activity, protein binding, protein kinase activity, protein serine/threonine kinase activity, transferase activity, transferring phosphorus-containing groups Human GAL Reactome UniProtKB {GO:0007631=GO_REF:0000019, GO:0032868=GO_REF:0000019, GO:0043627=GO_REF:0000019, GO:0005794=GO_REF:0000019, GO:0043065=GO_REF:0000019, GO:0042493=GO_REF:0000019, GO:0005576=Reactome:REACT_22289, GO:0005575=GO_REF:0000015, GO:0007399=GO_REF:0000019, GO:0050672=GO_REF:0000019, GO:0006939=GO_REF:0000029, GO:0006954=GO_REF:0000019, GO:0007218=GO_REF:0000019, GO:0030252=GO_REF:0000029, GO:0005184=PMID:1722333, GO:0030141=GO_REF:0000019, GO:0030073=PMID:1370155, GO:0031943=GO_REF:0000019} P22466 Galanin peptides protein 20081218 {GO:0007631=IEA, GO:0032868=IEA, GO:0043627=IEA, GO:0005794=IEA, GO:0043065=IEA, GO:0042493=IEA, GO:0005576=TAS, GO:0005575=ND, GO:0007399=IEA, GO:0050672=IEA, GO:0006939=NAS, GO:0006954=IEA, GO:0007218=IEA, GO:0030252=NAS, GO:0005184=NAS, GO:0030141=IEA, GO:0030073=NAS, GO:0031943=IEA} feeding behavior, growth hormone secretion, inflammatory response, insulin secretion, negative regulation of lymphocyte proliferation, nervous system development, neuropeptide signaling pathway, positive regulation of apoptotic process, regulation of glucocorticoid metabolic process, response to drug, response to estrogen stimulus, response to insulin stimulus, smooth muscle contraction Golgi apparatus, cellular_component, extracellular region, secretory granule neuropeptide hormone activity Human GAL3ST1 Reactome UniProtKB {GO:0006665=Reactome:REACT_19323, GO:0006682=GO_REF:0000019, GO:0005794=GO_REF:0000002, GO:0001733=GO_REF:0000003, GO:0006687=Reactome:REACT_116105, GO:0009058=GO_REF:0000002, GO:0042552=GO_REF:0000019, GO:0044281=Reactome:REACT_111217, GO:0007283=GO_REF:0000019, GO:0016020=PMID:9030544, GO:0000139=Reactome:REACT_115577, GO:0005887=PMID:9030544, GO:0008146=PMID:9030544, GO:0016021=GO_REF:0000002, GO:0006487=PMID:9030544} Q99999 Galactosylceramide sulfotransferase protein 20130301 {GO:0006665=TAS, GO:0006682=IEA, GO:0005794=IEA, GO:0001733=IEA, GO:0006687=TAS, GO:0009058=IEA, GO:0042552=IEA, GO:0044281=TAS, GO:0007283=IEA, GO:0016020=TAS, GO:0000139=TAS, GO:0005887=TAS, GO:0008146=TAS, GO:0016021=IEA, GO:0006487=TAS} biosynthetic process, galactosylceramide biosynthetic process, glycosphingolipid metabolic process, myelination, protein N-linked glycosylation, small molecule metabolic process, spermatogenesis, sphingolipid metabolic process Golgi apparatus, Golgi membrane, integral to membrane, integral to plasma membrane, membrane galactosylceramide sulfotransferase activity, sulfotransferase activity Human GAL3ST4 UniProtKB UniProtKB {GO:0006790=PMID:11333265, GO:0009311=PMID:11333265, GO:0001733=GO_REF:0000002, GO:0005794=GO_REF:0000002, GO:0009058=GO_REF:0000002, GO:0050698=PMID:11333265, GO:0007267=PMID:11333265, GO:0050694=PMID:11333265, GO:0050656=PMID:11333265, GO:0030166=PMID:11333265, GO:0009100=PMID:11333265, GO:0016020=PMID:11333265, GO:0032580=GO_REF:0000039, GO:0016021=PMID:11333265} Q96RP7 Galactose-3-O-sulfotransferase 4 protein 20031216 {GO:0006790=NAS, GO:0009311=NAS, GO:0001733=IEA, GO:0005794=IEA, GO:0009058=IEA, GO:0050698=NAS, GO:0007267=NAS, GO:0050694=IDA, GO:0050656=NAS, GO:0030166=NAS, GO:0009100=NAS, GO:0016020=IDA, GO:0032580=IEA, GO:0016021=NAS} biosynthetic process, cell-cell signaling, glycoprotein metabolic process, oligosaccharide metabolic process, proteoglycan biosynthetic process, sulfur compound metabolic process Golgi apparatus, Golgi cisterna membrane, integral to membrane, membrane 3'-phosphoadenosine 5'-phosphosulfate binding, galactose 3-O-sulfotransferase activity, galactosylceramide sulfotransferase activity, proteoglycan sulfotransferase activity Human GALC Reactome UniProtKB {GO:0006665=Reactome:REACT_19323, GO:0005739=GO_REF:0000019, GO:0006683=GO_REF:0000002, GO:0006687=Reactome:REACT_116105, GO:0005975=GO_REF:0000002, GO:0004336=GO_REF:0000003, GO:0044281=Reactome:REACT_111217, GO:0005764=PMID:7601472, GO:0043202=Reactome:REACT_115737} P54803 Galactocerebrosidase protein 20130301 {GO:0006665=TAS, GO:0005739=IEA, GO:0006683=IEA, GO:0006687=TAS, GO:0005975=IEA, GO:0004336=IEA, GO:0044281=TAS, GO:0005764=TAS, GO:0043202=TAS} carbohydrate metabolic process, galactosylceramide catabolic process, glycosphingolipid metabolic process, small molecule metabolic process, sphingolipid metabolic process lysosomal lumen, lysosome, mitochondrion galactosylceramidase activity Human GALE InterPro UniProtKB {GO:0050662=GO_REF:0000002, GO:0003978=GO_REF:0000002, GO:0005975=Reactome:REACT_474, GO:0019388=Reactome:REACT_532, GO:0044281=Reactome:REACT_111217, GO:0006012=GO_REF:0000002, GO:0042803=PMID:16302980, GO:0044237=GO_REF:0000002, GO:0005829=Reactome:REACT_1315} Q5QPP9 UDP-glucose 4-epimerase protein 20130413 {GO:0050662=IEA, GO:0003978=IEA, GO:0005975=TAS, GO:0019388=TAS, GO:0044281=TAS, GO:0006012=IEA, GO:0042803=IPI, GO:0044237=IEA, GO:0005829=TAS} carbohydrate metabolic process, cellular metabolic process, galactose catabolic process, galactose metabolic process, small molecule metabolic process cytosol UDP-glucose 4-epimerase activity, coenzyme binding, protein homodimerization activity Human InterPro:IPR005886 GALK1 Reactome UniProtKB {GO:0004335=PMID:12694189, GO:0005737=PMID:8908517, GO:0005534=PMID:14596685, GO:0016020=PMID:8908517, GO:0005975=Reactome:REACT_474, GO:0019388=Reactome:REACT_532, GO:0044281=Reactome:REACT_111217, GO:0006012=PMID:15024738, GO:0005524=PMID:12694189, GO:0005829=Reactome:REACT_1246} P51570 Galactokinase protein 20130301 {GO:0004335=IDA, GO:0005737=IDA, GO:0005534=IDA, GO:0016020=IDA, GO:0005975=TAS, GO:0019388=TAS, GO:0044281=TAS, GO:0006012=IMP, GO:0005524=IDA, GO:0005829=TAS} carbohydrate metabolic process, galactose catabolic process, galactose metabolic process, small molecule metabolic process cytoplasm, cytosol, membrane ATP binding, galactokinase activity, galactose binding Human GALK2 PINC UniProtKB {GO:0004335=PMID:7542884, GO:0005737=GO_REF:0000002, GO:0033858=GO_REF:0000003, GO:0005975=PMID:8798585, GO:0016301=GO_REF:0000038, GO:0016773=GO_REF:0000002, GO:0006012=GO_REF:0000002, GO:0005524=GO_REF:0000037} Q01415 N-acetylgalactosamine kinase protein 20030904 {GO:0004335=IDA, GO:0005737=IEA, GO:0033858=IEA, GO:0005975=TAS, GO:0016301=IEA, GO:0016773=IEA, GO:0006012=IEA, GO:0005524=IEA} carbohydrate metabolic process, galactose metabolic process cytoplasm ATP binding, N-acetylgalactosamine kinase activity, galactokinase activity, kinase activity, phosphotransferase activity, alcohol group as acceptor Human GALM UniPathway UniProtKB {GO:0005737=GO_REF:0000039, GO:0004034=GO_REF:0000003, GO:0030246=GO_REF:0000002, GO:0019318=GO_REF:0000041, GO:0016853=GO_REF:0000002} Q96C23 Aldose 1-epimerase protein 20130413 {GO:0005737=IEA, GO:0004034=IEA, GO:0030246=IEA, GO:0019318=IEA, GO:0016853=IEA} hexose metabolic process cytoplasm aldose 1-epimerase activity, carbohydrate binding, isomerase activity Human UniPathway:UPA00242 GALNS Reactome UniProtKB {GO:0003943=PMID:8325655, GO:0043890=GO_REF:0000003, GO:0005975=Reactome:REACT_474, GO:0042340=Reactome:REACT_121313, GO:0044281=Reactome:REACT_111217, GO:0008484=PMID:15962010, GO:0030203=Reactome:REACT_121315, GO:0046872=GO_REF:0000037, GO:0043202=Reactome:REACT_121094, GO:0042339=Reactome:REACT_121288} P34059 N-acetylgalactosamine-6-sulfatase protein 20130301 {GO:0003943=TAS, GO:0043890=IEA, GO:0005975=TAS, GO:0042340=TAS, GO:0044281=TAS, GO:0008484=IDA, GO:0030203=TAS, GO:0046872=IEA, GO:0043202=TAS, GO:0042339=TAS} carbohydrate metabolic process, glycosaminoglycan metabolic process, keratan sulfate catabolic process, keratan sulfate metabolic process, small molecule metabolic process lysosomal lumen N-acetylgalactosamine-4-sulfatase activity, N-acetylgalactosamine-6-sulfatase activity, metal ion binding, sulfuric ester hydrolase activity Human GALNT1 BHF-UCL UniProtKB {GO:0048471=PMID:12506059, GO:0030145=PMID:9295285, GO:0005794=PMID:12506059, GO:0016757=GO_REF:0000038, GO:0016266=Reactome:REACT_115606, GO:0005576=GO_REF:0000039, GO:0004653=PMID:9295285, GO:0006493=PMID:9592121, GO:0000139=Reactome:REACT_115586, GO:0018242=PMID:9295285, GO:0032580=GO_REF:0000039, GO:0018243=PMID:9295285, GO:0016021=GO_REF:0000037, GO:0044267=Reactome:REACT_17015, GO:0043687=Reactome:REACT_22161} Q10472 Polypeptide N-acetylgalactosaminyltransferase 1 protein 20080306 {GO:0048471=IDA, GO:0030145=IDA, GO:0005794=IDA, GO:0016757=IEA, GO:0016266=TAS, GO:0005576=IEA, GO:0004653=IDA, GO:0006493=TAS, GO:0000139=TAS, GO:0018242=IDA, GO:0032580=IEA, GO:0018243=IDA, GO:0016021=IEA, GO:0044267=TAS, GO:0043687=TAS} O-glycan processing, cellular protein metabolic process, post-translational protein modification, protein O-linked glycosylation, protein O-linked glycosylation via serine, protein O-linked glycosylation via threonine Golgi apparatus, Golgi cisterna membrane, Golgi membrane, extracellular region, integral to membrane, perinuclear region of cytoplasm manganese ion binding, polypeptide N-acetylgalactosaminyltransferase activity, transferase activity, transferring glycosyl groups Human GALNT10 Reactome UniProtKB {GO:0004653=GO_REF:0000003, GO:0000139=Reactome:REACT_115586, GO:0016757=GO_REF:0000038, GO:0016266=Reactome:REACT_115606, GO:0016021=GO_REF:0000037, GO:0044267=Reactome:REACT_17015, GO:0046872=GO_REF:0000037, GO:0043687=Reactome:REACT_22161} Q86SR1 Polypeptide N-acetylgalactosaminyltransferase 10 protein 20130301 {GO:0004653=IEA, GO:0000139=TAS, GO:0016757=IEA, GO:0016266=TAS, GO:0016021=IEA, GO:0044267=TAS, GO:0046872=IEA, GO:0043687=TAS} O-glycan processing, cellular protein metabolic process, post-translational protein modification Golgi membrane, integral to membrane metal ion binding, polypeptide N-acetylgalactosaminyltransferase activity, transferase activity, transferring glycosyl groups Human GALNT11 Reactome UniProtKB {GO:0004653=GO_REF:0000003, GO:0005794=GO_REF:0000038, GO:0000139=Reactome:REACT_115586, GO:0016757=GO_REF:0000038, GO:0016266=Reactome:REACT_115606, GO:0006486=GO_REF:0000041, GO:0016021=GO_REF:0000037, GO:0044267=Reactome:REACT_17015, GO:0016740=GO_REF:0000038, GO:0043687=Reactome:REACT_22161} Q8NCW6 Polypeptide N-acetylgalactosaminyltransferase 11 protein 20130301 {GO:0004653=IEA, GO:0005794=IEA, GO:0000139=TAS, GO:0016757=IEA, GO:0016266=TAS, GO:0006486=IEA, GO:0016021=IEA, GO:0044267=TAS, GO:0016740=IEA, GO:0043687=TAS} O-glycan processing, cellular protein metabolic process, post-translational protein modification, protein glycosylation Golgi apparatus, Golgi membrane, integral to membrane polypeptide N-acetylgalactosaminyltransferase activity, transferase activity, transferase activity, transferring glycosyl groups Human GALNT12 Reactome UniProtKB {GO:0004653=GO_REF:0000003, GO:0000139=Reactome:REACT_115586, GO:0016266=Reactome:REACT_115606, GO:0016021=GO_REF:0000037, GO:0044267=Reactome:REACT_17015, GO:0043687=Reactome:REACT_22161} Q8IXK2 Polypeptide N-acetylgalactosaminyltransferase 12 protein 20130301 {GO:0004653=IEA, GO:0000139=TAS, GO:0016266=TAS, GO:0016021=IEA, GO:0044267=TAS, GO:0043687=TAS} O-glycan processing, cellular protein metabolic process, post-translational protein modification Golgi membrane, integral to membrane polypeptide N-acetylgalactosaminyltransferase activity Human GALNT13 Reactome UniProtKB {GO:0004653=GO_REF:0000003, GO:0005794=GO_REF:0000038, GO:0000139=Reactome:REACT_115586, GO:0016757=GO_REF:0000038, GO:0016266=Reactome:REACT_115606, GO:0006486=GO_REF:0000041, GO:0016021=GO_REF:0000037, GO:0044267=Reactome:REACT_17015, GO:0043687=Reactome:REACT_22161} Q8IUC8 Polypeptide N-acetylgalactosaminyltransferase 13 protein 20130301 {GO:0004653=IEA, GO:0005794=IEA, GO:0000139=TAS, GO:0016757=IEA, GO:0016266=TAS, GO:0006486=IEA, GO:0016021=IEA, GO:0044267=TAS, GO:0043687=TAS} O-glycan processing, cellular protein metabolic process, post-translational protein modification, protein glycosylation Golgi apparatus, Golgi membrane, integral to membrane polypeptide N-acetylgalactosaminyltransferase activity, transferase activity, transferring glycosyl groups Human GALNT14 Reactome UniProtKB {GO:0004653=GO_REF:0000003, GO:0005794=GO_REF:0000038, GO:0000139=Reactome:REACT_115586, GO:0005975=GO_REF:0000002, GO:0016757=GO_REF:0000038, GO:0016266=Reactome:REACT_115606, GO:0006486=GO_REF:0000041, GO:0016021=GO_REF:0000037, GO:0044267=Reactome:REACT_17015, GO:0043687=Reactome:REACT_22161} Q96FL9 Polypeptide N-acetylgalactosaminyltransferase 14 protein 20130301 {GO:0004653=IEA, GO:0005794=IEA, GO:0000139=TAS, GO:0005975=IEA, GO:0016757=IEA, GO:0016266=TAS, GO:0006486=IEA, GO:0016021=IEA, GO:0044267=TAS, GO:0043687=TAS} O-glycan processing, carbohydrate metabolic process, cellular protein metabolic process, post-translational protein modification, protein glycosylation Golgi apparatus, Golgi membrane, integral to membrane polypeptide N-acetylgalactosaminyltransferase activity, transferase activity, transferring glycosyl groups Human GALNT2 HPA UniProtKB {GO:0048471=PMID:12506059, GO:0030145=PMID:9295285, GO:0005794=GO_REF:0000052, GO:0005795=PMID:9852147, GO:0016757=GO_REF:0000038, GO:0016266=Reactome:REACT_115606, GO:0005576=GO_REF:0000039, GO:0002378=PMID:12438318, GO:0004653=PMID:9295285, GO:0030173=PMID:9852147, GO:0000139=Reactome:REACT_115586, GO:0018242=PMID:9295285, GO:0032580=GO_REF:0000039, GO:0018243=PMID:9295285, GO:0006486=GO_REF:0000041, GO:0016021=GO_REF:0000038, GO:0044267=Reactome:REACT_17015, GO:0043687=Reactome:REACT_22161} Q10471 Polypeptide N-acetylgalactosaminyltransferase 2 protein 20081203 {GO:0048471=IDA, GO:0030145=IDA, GO:0005794=IDA, GO:0005795=IDA, GO:0016757=IEA, GO:0016266=TAS, GO:0005576=IEA, GO:0002378=IDA, GO:0004653=IDA, GO:0030173=NAS, GO:0000139=TAS, GO:0018242=IDA, GO:0032580=IEA, GO:0018243=IDA, GO:0006486=IEA, GO:0016021=IEA, GO:0044267=TAS, GO:0043687=TAS} O-glycan processing, cellular protein metabolic process, immunoglobulin biosynthetic process, post-translational protein modification, protein O-linked glycosylation via serine, protein O-linked glycosylation via threonine, protein glycosylation Golgi apparatus, Golgi cisterna membrane, Golgi membrane, Golgi stack, extracellular region, integral to Golgi membrane, integral to membrane, perinuclear region of cytoplasm manganese ion binding, polypeptide N-acetylgalactosaminyltransferase activity, transferase activity, transferring glycosyl groups Human GALNT4 BHF-UCL UniProtKB {GO:0048471=PMID:12506059, GO:0004653=GO_REF:0000003, GO:0005794=PMID:12506059, GO:0000139=Reactome:REACT_115586, GO:0005975=PMID:9592121, GO:0016266=Reactome:REACT_115606, GO:0016021=GO_REF:0000037, GO:0044267=Reactome:REACT_17015, GO:0043687=Reactome:REACT_22161} Q8N4A0 Polypeptide N-acetylgalactosaminyltransferase 4 protein 20080306 {GO:0048471=IDA, GO:0004653=IEA, GO:0005794=IDA, GO:0000139=TAS, GO:0005975=NAS, GO:0016266=TAS, GO:0016021=IEA, GO:0044267=TAS, GO:0043687=TAS} O-glycan processing, carbohydrate metabolic process, cellular protein metabolic process, post-translational protein modification Golgi apparatus, Golgi membrane, integral to membrane, perinuclear region of cytoplasm polypeptide N-acetylgalactosaminyltransferase activity Human GALNT5 Reactome UniProtKB {GO:0004653=PMID:10545594, GO:0000139=Reactome:REACT_115586, GO:0016266=Reactome:REACT_115606, GO:0005575=GO_REF:0000015, GO:0016021=GO_REF:0000037, GO:0044267=Reactome:REACT_17015, GO:0006024=PMID:10545594, GO:0043687=Reactome:REACT_22161} Q7Z7M9 Polypeptide N-acetylgalactosaminyltransferase 5 protein 20130301 {GO:0004653=IDA, GO:0000139=TAS, GO:0016266=TAS, GO:0005575=ND, GO:0016021=IEA, GO:0044267=TAS, GO:0006024=TAS, GO:0043687=TAS} O-glycan processing, cellular protein metabolic process, glycosaminoglycan biosynthetic process, post-translational protein modification Golgi membrane, cellular_component, integral to membrane polypeptide N-acetylgalactosaminyltransferase activity Human GALNT6 BHF-UCL UniProtKB {GO:0048471=PMID:12506059, GO:0004653=GO_REF:0000003, GO:0005794=PMID:12506059, GO:0000139=Reactome:REACT_115586, GO:0006493=PMID:10464263, GO:0016266=Reactome:REACT_115606, GO:0016021=GO_REF:0000037, GO:0044267=Reactome:REACT_17015, GO:0043687=Reactome:REACT_22161} Q8NCL4 Polypeptide N-acetylgalactosaminyltransferase 6 protein 20080306 {GO:0048471=IDA, GO:0004653=IEA, GO:0005794=IDA, GO:0000139=TAS, GO:0006493=TAS, GO:0016266=TAS, GO:0016021=IEA, GO:0044267=TAS, GO:0043687=TAS} O-glycan processing, cellular protein metabolic process, post-translational protein modification, protein O-linked glycosylation Golgi apparatus, Golgi membrane, integral to membrane, perinuclear region of cytoplasm polypeptide N-acetylgalactosaminyltransferase activity Human GALNT7 Reactome UniProtKB {GO:0004653=GO_REF:0000019, GO:0005794=GO_REF:0000038, GO:0000139=Reactome:REACT_115586, GO:0006493=PMID:10544240, GO:0005975=PMID:10544240, GO:0016757=GO_REF:0000038, GO:0016266=Reactome:REACT_115606, GO:0006486=GO_REF:0000041, GO:0016021=GO_REF:0000037, GO:0044267=Reactome:REACT_17015, GO:0043687=Reactome:REACT_22161} Q86SF2 N-acetylgalactosaminyltransferase 7 protein 20130301 {GO:0004653=IEA, GO:0005794=IEA, GO:0000139=TAS, GO:0006493=TAS, GO:0005975=TAS, GO:0016757=IEA, GO:0016266=TAS, GO:0006486=IEA, GO:0016021=IEA, GO:0044267=TAS, GO:0043687=TAS} O-glycan processing, carbohydrate metabolic process, cellular protein metabolic process, post-translational protein modification, protein O-linked glycosylation, protein glycosylation Golgi apparatus, Golgi membrane, integral to membrane polypeptide N-acetylgalactosaminyltransferase activity, transferase activity, transferring glycosyl groups Human GALNTL5 UniPathway UniProtKB {GO:0000139=GO_REF:0000039, GO:0016757=GO_REF:0000037, GO:0006486=GO_REF:0000041, GO:0016021=GO_REF:0000037, GO:0016740=GO_REF:0000038} Q7Z4T8 Putative polypeptide N-acetylgalactosaminyltransferase-like protein 5 protein 20130413 {GO:0000139=IEA, GO:0016757=IEA, GO:0006486=IEA, GO:0016021=IEA, GO:0016740=IEA} protein glycosylation Golgi membrane, integral to membrane transferase activity, transferase activity, transferring glycosyl groups Human UniPathway:UPA00378 GALR1 Reactome UniProtKB {GO:0005886=Reactome:REACT_22289, GO:0042923=GO_REF:0000019, GO:0007218=PMID:7524088, GO:0007586=PMID:8670213, GO:0004966=GO_REF:0000019, GO:0007189=GO_REF:0000019, GO:0016021=GO_REF:0000037, GO:0007194=PMID:7524088} P47211 Galanin receptor type 1 protein 20081218 {GO:0005886=TAS, GO:0042923=IEA, GO:0007218=TAS, GO:0007586=TAS, GO:0004966=IEA, GO:0007189=IEA, GO:0016021=IEA, GO:0007194=TAS} adenylate cyclase-activating G-protein coupled receptor signaling pathway, digestion, negative regulation of adenylate cyclase activity, neuropeptide signaling pathway integral to membrane, plasma membrane galanin receptor activity, neuropeptide binding Human GALR2 Reactome UniProtKB {GO:0007631=PMID:9480833, GO:0005886=Reactome:REACT_22289, GO:0007586=PMID:9832121, GO:0004966=GO_REF:0000002, GO:0007268=PMID:9832121, GO:0007275=PMID:9480833, GO:0007204=PMID:9685625, GO:0031175=GO_REF:0000019, GO:0006936=PMID:9480833, GO:0007611=PMID:9480833, GO:0007188=PMID:9685625, GO:0016021=GO_REF:0000037, GO:0007166=PMID:9480833} O43603 Galanin receptor type 2 protein 20081218 {GO:0007631=TAS, GO:0005886=TAS, GO:0007586=TAS, GO:0004966=IEA, GO:0007268=TAS, GO:0007275=TAS, GO:0007204=TAS, GO:0031175=IEA, GO:0006936=TAS, GO:0007611=TAS, GO:0007188=TAS, GO:0016021=IEA, GO:0007166=TAS} adenylate cyclase-modulating G-protein coupled receptor signaling pathway, cell surface receptor signaling pathway, digestion, elevation of cytosolic calcium ion concentration, feeding behavior, learning or memory, multicellular organismal development, muscle contraction, neuron projection development, synaptic transmission integral to membrane, plasma membrane galanin receptor activity Human GALR3 Reactome UniProtKB {GO:0007631=PMID:9722565, GO:0005886=Reactome:REACT_22289, GO:0007218=PMID:9722565, GO:0007611=PMID:9722565, GO:0007268=PMID:9722565, GO:0004966=GO_REF:0000002, GO:0016021=GO_REF:0000037, GO:0007194=PMID:9832121} O60755 Galanin receptor type 3 protein 20081218 {GO:0007631=TAS, GO:0005886=TAS, GO:0007218=TAS, GO:0007611=TAS, GO:0007268=TAS, GO:0004966=IEA, GO:0016021=IEA, GO:0007194=TAS} feeding behavior, learning or memory, negative regulation of adenylate cyclase activity, neuropeptide signaling pathway, synaptic transmission integral to membrane, plasma membrane galanin receptor activity Human GALT Reactome UniProtKB {GO:0005794=PMID:20605918, GO:0005975=Reactome:REACT_474, GO:0008108=GO_REF:0000003, GO:0019388=Reactome:REACT_532, GO:0006258=GO_REF:0000019, GO:0008270=GO_REF:0000002, GO:0044281=Reactome:REACT_111217, GO:0006012=PMID:1427861, GO:0005829=Reactome:REACT_2047} P07902 Galactose-1-phosphate uridylyltransferase protein 20130301 {GO:0005794=IDA, GO:0005975=TAS, GO:0008108=IEA, GO:0019388=TAS, GO:0006258=IEA, GO:0008270=IEA, GO:0044281=TAS, GO:0006012=TAS, GO:0005829=TAS} UDP-glucose catabolic process, carbohydrate metabolic process, galactose catabolic process, galactose metabolic process, small molecule metabolic process Golgi apparatus, cytosol UDP-glucose:hexose-1-phosphate uridylyltransferase activity, zinc ion binding Human GAMT Reactome UniProtKB {GO:0030731=PMID:8651275, GO:0034641=Reactome:REACT_13, GO:0006936=PMID:8547310, GO:0006601=PMID:8651275, GO:0006600=Reactome:REACT_813, GO:0008168=PMID:9325156, GO:0040014=GO_REF:0000019, GO:0009887=GO_REF:0000019, GO:0044281=Reactome:REACT_111217, GO:0007283=GO_REF:0000019, GO:0005829=Reactome:REACT_2094} Q14353 Guanidinoacetate N-methyltransferase protein 20130301 {GO:0030731=IMP, GO:0034641=TAS, GO:0006936=TAS, GO:0006601=IDA, GO:0006600=TAS, GO:0008168=TAS, GO:0040014=IEA, GO:0009887=IEA, GO:0044281=TAS, GO:0007283=IEA, GO:0005829=TAS} cellular nitrogen compound metabolic process, creatine biosynthetic process, creatine metabolic process, muscle contraction, organ morphogenesis, regulation of multicellular organism growth, small molecule metabolic process, spermatogenesis cytosol guanidinoacetate N-methyltransferase activity, methyltransferase activity Human GAN IntAct UniProtKB {GO:0005515=PMID:16303566, GO:0008150=GO_REF:0000015, GO:0003674=GO_REF:0000015, GO:0008219=GO_REF:0000037, GO:0005737=PMID:19424503, GO:0016567=PMID:15983046, GO:0005883=GO_REF:0000029, GO:0031463=PMID:15983046} Q9H2C0 Gigaxonin protein 20130415 {GO:0005515=IPI, GO:0008150=ND, GO:0003674=ND, GO:0008219=IEA, GO:0005737=IDA, GO:0016567=IDA, GO:0005883=NAS, GO:0031463=IDA} biological_process, cell death, protein ubiquitination Cul3-RING ubiquitin ligase complex, cytoplasm, neurofilament molecular_function, protein binding Human UniProtKB:Q99426 GANAB Reactome UniProtKB {GO:0033919=GO_REF:0000003, GO:0042470=GO_REF:0000039, GO:0017177=GO_REF:0000019, GO:0005794=GO_REF:0000039, GO:0006457=Reactome:REACT_23878, GO:0005975=GO_REF:0000002, GO:0005788=Reactome:REACT_23850, GO:0030246=GO_REF:0000002, GO:0044267=Reactome:REACT_17015, GO:0004553=GO_REF:0000002, GO:0043687=Reactome:REACT_22161, GO:0018279=Reactome:REACT_22426} Q14697 Neutral alpha-glucosidase AB protein 20100302 {GO:0033919=IEA, GO:0042470=IEA, GO:0017177=IEA, GO:0005794=IEA, GO:0006457=TAS, GO:0005975=IEA, GO:0005788=TAS, GO:0030246=IEA, GO:0044267=TAS, GO:0004553=IEA, GO:0043687=TAS, GO:0018279=TAS} carbohydrate metabolic process, cellular protein metabolic process, post-translational protein modification, protein N-linked glycosylation via asparagine, protein folding Golgi apparatus, endoplasmic reticulum lumen, glucosidase II complex, melanosome carbohydrate binding, glucan 1,3-alpha-glucosidase activity, hydrolase activity, hydrolyzing O-glycosyl compounds Human GANC UniProtKB UniProtKB {GO:0032450=GO_REF:0000003, GO:0005975=GO_REF:0000002, GO:0030246=GO_REF:0000002, GO:0004553=GO_REF:0000002, GO:0004558=PMID:12370436} Q8TET4 Neutral alpha-glucosidase C protein 20041109 {GO:0032450=IEA, GO:0005975=IEA, GO:0030246=IEA, GO:0004553=IEA, GO:0004558=NAS} carbohydrate metabolic process alpha-glucosidase activity, carbohydrate binding, hydrolase activity, hydrolyzing O-glycosyl compounds, maltose alpha-glucosidase activity Human GAP43 IntAct UniProtKB {GO:0005515=PMID:9139733, GO:0005516=GO_REF:0000037, GO:0030424=GO_REF:0000019, GO:0030054=GO_REF:0000037, GO:0005886=GO_REF:0000054, GO:0009611=PMID:3272162, GO:0031527=PMID:14978216, GO:0032584=GO_REF:0000039, GO:0045202=GO_REF:0000039, GO:0042246=GO_REF:0000019, GO:0007205=PMID:3272162, GO:0051489=PMID:14978216, GO:0045165=GO_REF:0000019, GO:0016198=GO_REF:0000019, GO:0010001=GO_REF:0000019, GO:0040008=GO_REF:0000037} P17677 Neuromodulin protein 20130415 {GO:0005515=IPI, GO:0005516=IEA, GO:0030424=IEA, GO:0030054=IEA, GO:0005886=IDA, GO:0009611=TAS, GO:0031527=IDA, GO:0032584=IEA, GO:0045202=IEA, GO:0042246=IEA, GO:0007205=TAS, GO:0051489=IDA, GO:0045165=IEA, GO:0016198=IEA, GO:0010001=IEA, GO:0040008=IEA} axon choice point recognition, cell fate commitment, glial cell differentiation, protein kinase C-activating G-protein coupled receptor signaling pathway, regulation of filopodium assembly, regulation of growth, response to wounding, tissue regeneration axon, cell junction, filopodium membrane, growth cone membrane, plasma membrane, synapse calmodulin binding, protein binding Human UniProtKB:Q05655 GAPDH HPA UniProtKB {GO:0017148=PMID:23071094, GO:0008017=GO_REF:0000024, GO:0050661=GO_REF:0000002, GO:0005515=PMID:20029029, GO:0035605=GO_REF:0000024, GO:0048471=GO_REF:0000039, GO:0005886=GO_REF:0000052, GO:0005975=Reactome:REACT_474, GO:0006094=Reactome:REACT_1520, GO:0050821=GO_REF:0000024, GO:0000226=GO_REF:0000024, GO:0005634=GO_REF:0000024, GO:0044281=Reactome:REACT_111217, GO:0004365=GO_REF:0000024, GO:0051402=GO_REF:0000024, GO:0006096=Reactome:REACT_1383, GO:0035606=GO_REF:0000024, GO:0005829=Reactome:REACT_1847, GO:0005737=GO_REF:0000052, GO:0051287=GO_REF:0000002, GO:0071346=PMID:15479637, GO:0030529=PMID:15479637, GO:0015630=GO_REF:0000024, GO:0006006=Reactome:REACT_723} P04406 Glyceraldehyde-3-phosphate dehydrogenase protein 20120912 {GO:0017148=IDA, GO:0008017=ISS, GO:0050661=IEA, GO:0005515=IPI, GO:0035605=ISS, GO:0048471=IEA, GO:0005886=IDA, GO:0005975=TAS, GO:0006094=TAS, GO:0050821=ISS, GO:0000226=ISS, GO:0005634=ISS, GO:0044281=TAS, GO:0004365=ISS, GO:0051402=ISS, GO:0006096=TAS, GO:0035606=ISS, GO:0005829=TAS, GO:0005737=IDA, GO:0051287=IEA, GO:0071346=IDA, GO:0030529=IDA, GO:0015630=ISS, GO:0006006=TAS} carbohydrate metabolic process, cellular response to interferon-gamma, gluconeogenesis, glucose metabolic process, glycolysis, microtubule cytoskeleton organization, negative regulation of translation, neuron apoptotic process, peptidyl-cysteine S-trans-nitrosylation, protein stabilization, small molecule metabolic process cytoplasm, cytosol, microtubule cytoskeleton, nucleus, perinuclear region of cytoplasm, plasma membrane, ribonucleoprotein complex NAD binding, NADP binding, glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity, microtubule binding, peptidyl-cysteine S-nitrosylase activity, protein binding Human GAPDHS Reactome UniProtKB {GO:0050661=GO_REF:0000002, GO:0005515=PMID:16820410, GO:0005975=Reactome:REACT_474, GO:0007286=GO_REF:0000019, GO:0006094=Reactome:REACT_1520, GO:0044281=Reactome:REACT_111217, GO:0030317=GO_REF:0000024, GO:0004365=PMID:10714828, GO:0006096=Reactome:REACT_1383, GO:0005829=Reactome:REACT_1847, GO:0051287=GO_REF:0000002, GO:0016620=GO_REF:0000002, GO:0006006=Reactome:REACT_723, GO:0045821=PMID:10714828} O14556 Glyceraldehyde-3-phosphate dehydrogenase, testis-specific protein 20130213 {GO:0050661=IEA, GO:0005515=IPI, GO:0005975=TAS, GO:0007286=IEA, GO:0006094=TAS, GO:0044281=TAS, GO:0030317=ISS, GO:0004365=TAS, GO:0006096=TAS, GO:0005829=TAS, GO:0051287=IEA, GO:0016620=IEA, GO:0006006=TAS, GO:0045821=TAS} carbohydrate metabolic process, gluconeogenesis, glucose metabolic process, glycolysis, positive regulation of glycolysis, small molecule metabolic process, sperm motility, spermatid development cytosol NAD binding, NADP binding, glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity, oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor, protein binding Human GAPVD1 UniProtKB UniProtKB {GO:0032794=PMID:16410077, GO:0005085=PMID:16410077, GO:0005622=GO_REF:0000002, GO:0051056=GO_REF:0000002, GO:0007165=GO_REF:0000002, GO:0016020=GO_REF:0000039, GO:0005768=GO_REF:0000039, GO:0006897=GO_REF:0000037, GO:0051223=PMID:16410077, GO:0005829=PMID:16410077, GO:0005096=GO_REF:0000037} Q14C86 GTPase-activating protein and VPS9 domain-containing protein 1 protein 20080314 {GO:0032794=IMP, GO:0005085=IMP, GO:0005622=IEA, GO:0051056=IEA, GO:0007165=IEA, GO:0016020=IEA, GO:0005768=IEA, GO:0006897=IEA, GO:0051223=IMP, GO:0005829=IDA, GO:0005096=IEA} endocytosis, regulation of protein transport, regulation of small GTPase mediated signal transduction, signal transduction cytosol, endosome, intracellular, membrane GTPase activating protein binding, GTPase activator activity, guanyl-nucleotide exchange factor activity Human GAR1 PINC UniProtKB {GO:0009982=GO_REF:0000002, GO:0005261=PMID:8766832, GO:0015030=GO_REF:0000039, GO:0030515=GO_REF:0000002, GO:0031429=GO_REF:0000002, GO:0006364=GO_REF:0000037, GO:0031120=GO_REF:0000002} Q9NY12 H/ACA ribonucleoprotein complex subunit 1 protein 20030904 {GO:0009982=IEA, GO:0005261=TAS, GO:0015030=IEA, GO:0030515=IEA, GO:0031429=IEA, GO:0006364=IEA, GO:0031120=IEA} rRNA processing, snRNA pseudouridine synthesis Cajal body, box H/ACA snoRNP complex cation channel activity, pseudouridine synthase activity, snoRNA binding Human GARNL3 UniProtKB UniProtKB {GO:0051056=GO_REF:0000002, GO:0005083=GO_REF:0000002, GO:0005096=GO_REF:0000037} Q5VVW2 GTPase-activating Rap/Ran-GAP domain-like protein 3 protein 20130413 {GO:0051056=IEA, GO:0005083=IEA, GO:0005096=IEA} regulation of small GTPase mediated signal transduction GTPase activator activity, small GTPase regulator activity Human UniProtKB-KW:KW-0343 GARS HPA UniProtKB {GO:0010467=Reactome:REACT_71, GO:0008219=GO_REF:0000037, GO:0005737=GO_REF:0000052, GO:0015966=PMID:19710017, GO:0005759=Reactome:REACT_15471, GO:0046983=PMID:17545306, GO:0030141=GO_REF:0000019, GO:0005524=GO_REF:0000037, GO:0006426=GO_REF:0000002, GO:0006418=Reactome:REACT_15482, GO:0005829=Reactome:REACT_15522, GO:0004820=Reactome:REACT_15522} P41250 Glycine--tRNA ligase protein 20101115 {GO:0010467=TAS, GO:0008219=IEA, GO:0005737=IDA, GO:0015966=IDA, GO:0005759=TAS, GO:0046983=IDA, GO:0030141=IEA, GO:0005524=IEA, GO:0006426=IEA, GO:0006418=TAS, GO:0005829=TAS, GO:0004820=TAS} cell death, diadenosine tetraphosphate biosynthetic process, gene expression, glycyl-tRNA aminoacylation, tRNA aminoacylation for protein translation cytoplasm, cytosol, mitochondrial matrix, secretory granule ATP binding, glycine-tRNA ligase activity, protein dimerization activity Human GART Reactome UniProtKB {GO:0009168=Reactome:REACT_1776, GO:0008168=GO_REF:0000002, GO:0055086=Reactome:REACT_1698, GO:0044281=Reactome:REACT_111217, GO:0004637=GO_REF:0000003, GO:0003824=GO_REF:0000002, GO:0004644=GO_REF:0000003, GO:0005524=GO_REF:0000037, GO:0046872=GO_REF:0000037, GO:0005829=Reactome:REACT_1917, GO:0005737=GO_REF:0000002, GO:0004641=GO_REF:0000003, GO:0006144=Reactome:REACT_522, GO:0009113=GO_REF:0000002, GO:0006189=GO_REF:0000041} P22102 Trifunctional purine biosynthetic protein adenosine-3 protein 20130301 {GO:0009168=TAS, GO:0008168=IEA, GO:0055086=TAS, GO:0044281=TAS, GO:0004637=IEA, GO:0003824=IEA, GO:0004644=IEA, GO:0005524=IEA, GO:0046872=IEA, GO:0005829=TAS, GO:0005737=IEA, GO:0004641=IEA, GO:0006144=TAS, GO:0009113=IEA, GO:0006189=IEA} 'de novo' IMP biosynthetic process, nucleobase-containing small molecule metabolic process, purine nucleobase biosynthetic process, purine nucleobase metabolic process, purine ribonucleoside monophosphate biosynthetic process, small molecule metabolic process cytoplasm, cytosol ATP binding, catalytic activity, metal ion binding, methyltransferase activity, phosphoribosylamine-glycine ligase activity, phosphoribosylformylglycinamidine cyclo-ligase activity, phosphoribosylglycinamide formyltransferase activity Human GAS1 MGI UniProtKB {GO:0005515=PMID:21357679, GO:0035924=PMID:15070677, GO:0030308=GO_REF:0000019, GO:0005886=PMID:8127893, GO:0060628=PMID:21357679, GO:0050680=GO_REF:0000019, GO:0045879=GO_REF:0000019, GO:0048592=GO_REF:0000019, GO:0048701=GO_REF:0000019, GO:0045880=GO_REF:0000019, GO:0048589=GO_REF:0000024, GO:0007411=GO_REF:0000019, GO:0042476=GO_REF:0000019, GO:0060021=GO_REF:0000019, GO:0007050=GO_REF:0000037, GO:0021904=GO_REF:0000019, GO:0042474=GO_REF:0000019, GO:0043010=GO_REF:0000019, GO:0042473=GO_REF:0000019, GO:0046658=GO_REF:0000024, GO:0050679=GO_REF:0000019, GO:0043066=GO_REF:0000019, GO:0021587=GO_REF:0000019, GO:0002053=GO_REF:0000019, GO:0042981=GO_REF:0000024, GO:0012501=GO_REF:0000019, GO:0045165=GO_REF:0000024, GO:0045930=PMID:11356029, GO:0008589=GO_REF:0000024, GO:0016021=PMID:8127893, GO:0042733=GO_REF:0000019} P54826 Growth arrest-specific protein 1 protein 20080820 {GO:0005515=IPI, GO:0035924=IEP, GO:0030308=IEA, GO:0005886=IDA, GO:0060628=IMP, GO:0050680=IEA, GO:0045879=IEA, GO:0048592=IEA, GO:0048701=IEA, GO:0045880=IEA, GO:0048589=ISS, GO:0007411=IEA, GO:0042476=IEA, GO:0060021=IEA, GO:0007050=IEA, GO:0021904=IEA, GO:0042474=IEA, GO:0043010=IEA, GO:0042473=IEA, GO:0046658=ISS, GO:0050679=IEA, GO:0043066=IEA, GO:0021587=IEA, GO:0002053=IEA, GO:0042981=ISS, GO:0012501=IEA, GO:0045165=ISS, GO:0045930=IGI, GO:0008589=ISS, GO:0016021=NAS, GO:0042733=IEA} axon guidance, camera-type eye development, cell cycle arrest, cell fate commitment, cellular response to vascular endothelial growth factor stimulus, cerebellum morphogenesis, developmental growth, dorsal/ventral neural tube patterning, embryonic cranial skeleton morphogenesis, embryonic digit morphogenesis, eye morphogenesis, middle ear morphogenesis, negative regulation of apoptotic process, negative regulation of cell growth, negative regulation of epithelial cell proliferation, negative regulation of mitotic cell cycle, negative regulation of smoothened signaling pathway, odontogenesis, outer ear morphogenesis, palate development, positive regulation of epithelial cell proliferation, positive regulation of mesenchymal cell proliferation, positive regulation of smoothened signaling pathway, programmed cell death, regulation of ER to Golgi vesicle-mediated transport, regulation of apoptotic process, regulation of smoothened signaling pathway anchored to plasma membrane, integral to membrane, plasma membrane protein binding Human UniProtKB:P04637 GAS2 Reactome UniProtKB {GO:0016020=GO_REF:0000039, GO:0005884=PMID:1607387, GO:0008360=GO_REF:0000037, GO:0006915=Reactome:REACT_578, GO:0007050=GO_REF:0000037, GO:0006921=Reactome:REACT_995, GO:0005829=Reactome:REACT_12004} O43903 Growth arrest-specific protein 2 protein 20130301 {GO:0016020=IEA, GO:0005884=TAS, GO:0008360=IEA, GO:0006915=TAS, GO:0007050=IEA, GO:0006921=TAS, GO:0005829=TAS} apoptotic process, cell cycle arrest, cellular component disassembly involved in execution phase of apoptosis, regulation of cell shape actin filament, cytosol, membrane Human GAS2L1 UniProtKB UniProtKB {GO:0046966=PMID:19375645, GO:0097067=PMID:19375645, GO:0005737=GO_REF:0000037, GO:0001725=GO_REF:0000019, GO:0005874=GO_REF:0000019, GO:0007050=PMID:12584248, GO:0009267=PMID:12584248} Q99501 GAS2-like protein 1 protein 20111029 {GO:0046966=IDA, GO:0097067=IDA, GO:0005737=IEA, GO:0001725=IEA, GO:0005874=IEA, GO:0007050=ISS, GO:0009267=ISS} cell cycle arrest, cellular response to starvation, cellular response to thyroid hormone stimulus cytoplasm, microtubule, stress fiber thyroid hormone receptor binding Human UniProtKB:Q8JZP9-1 GAS2L2 UniProtKB UniProtKB {GO:0005737=GO_REF:0000037, GO:0007050=GO_REF:0000002, GO:0005856=GO_REF:0000039} Q8NHY3 GAS2-like protein 2 protein 20130413 {GO:0005737=IEA, GO:0007050=IEA, GO:0005856=IEA} cell cycle arrest cytoplasm, cytoskeleton Human UniProtKB-SubCell:SL-0090 GAS2L3 UniProtKB UniProtKB {GO:0008017=PMID:21561867, GO:0005737=GO_REF:0000039, GO:0030036=PMID:21561867, GO:0015630=PMID:21561867, GO:0005874=GO_REF:0000037, GO:0000226=PMID:21561867, GO:0003779=PMID:21561867, GO:0007050=GO_REF:0000002, GO:0015629=PMID:21561867} Q86XJ1 GAS2-like protein 3 protein 20121121 {GO:0008017=IDA, GO:0005737=IEA, GO:0030036=IDA, GO:0015630=IDA, GO:0005874=IEA, GO:0000226=IDA, GO:0003779=IDA, GO:0007050=IEA, GO:0015629=IDA} actin cytoskeleton organization, cell cycle arrest, microtubule cytoskeleton organization actin cytoskeleton, cytoplasm, microtubule, microtubule cytoskeleton actin binding, microtubule binding Human GAS6 Reactome UniProtKB {GO:0005515=PMID:18760998, GO:0006909=PMID:21501828, GO:0032715=PMID:19657094, GO:0050900=Reactome:REACT_12051, GO:0071307=PMID:16359517, GO:0005615=PMID:8336730, GO:2000510=PMID:19657094, GO:0060090=PMID:21501828, GO:0006508=Reactome:REACT_733, GO:0070374=PMID:15184064, GO:0048018=PMID:15184064, GO:0043027=PMID:16723520, GO:0005796=Reactome:REACT_1117, GO:0019064=PMID:21501828, GO:0005509=GO_REF:0000002, GO:0031589=GO_REF:0000019, GO:0043277=PMID:21501828, GO:0032720=PMID:19657094, GO:0030168=Reactome:REACT_798, GO:2000669=PMID:19657094, GO:0010804=PMID:19657094, GO:0010934=GO_REF:0000019, GO:0043491=PMID:16723520, GO:0070588=PMID:18395422, GO:0035754=PMID:19922767, GO:0001786=PMID:21501828, GO:0005788=Reactome:REACT_1, GO:0044267=Reactome:REACT_17015, GO:0040008=GO_REF:0000037, GO:0043687=Reactome:REACT_22161, GO:0051897=PMID:16723520, GO:0032008=GO_REF:0000024, GO:0008283=PMID:16564713, GO:0035457=PMID:19657094, GO:0031100=GO_REF:0000019, GO:2000533=GO_REF:0000024, GO:0048146=PMID:15184064, GO:0046718=PMID:21501828, GO:0097028=PMID:19657094, GO:0019079=PMID:21501828, GO:0085029=GO_REF:0000024, GO:0032148=GO_REF:0000024, GO:0031093=Reactome:REACT_21351, GO:0007050=PMID:16564713, GO:0007155=PMID:16564713, GO:0071333=GO_REF:0000024, GO:0043154=PMID:16723520, GO:0009267=GO_REF:0000019, GO:0030971=PMID:7634325, GO:0043066=PMID:19922767, GO:0005245=PMID:18395422, GO:0005102=PMID:7854420, GO:0070168=PMID:20048160, GO:0005576=Reactome:REACT_21351, GO:0003104=GO_REF:0000024, GO:0070527=PMID:16564713, GO:0007165=PMID:7854420, GO:0017187=Reactome:REACT_1132, GO:0016477=PMID:16564713, GO:0071363=GO_REF:0000019, GO:0007596=Reactome:REACT_604, GO:0002576=Reactome:REACT_318, GO:0001934=PMID:16723520, GO:0001764=GO_REF:0000019, GO:2000352=PMID:18760998, GO:0046813=PMID:21501828, GO:0097241=PMID:19922767, GO:0007167=GO_REF:0000019} Q14393 Growth arrest-specific protein 6 protein 20130301 {GO:0005515=IPI, GO:0006909=IDA, GO:0032715=IDA, GO:0050900=TAS, GO:0071307=IDA, GO:0005615=IDA, GO:2000510=IDA, GO:0060090=IDA, GO:0006508=TAS, GO:0070374=IDA, GO:0048018=IDA, GO:0043027=IDA, GO:0005796=TAS, GO:0019064=IDA, GO:0005509=IEA, GO:0031589=IEA, GO:0043277=IDA, GO:0032720=IDA, GO:0030168=TAS, GO:2000669=IDA, GO:0010804=IDA, GO:0010934=IEA, GO:0043491=IDA, GO:0070588=IDA, GO:0035754=IDA, GO:0001786=IDA, GO:0005788=TAS, GO:0044267=TAS, GO:0040008=IEA, GO:0043687=TAS, GO:0051897=IDA, GO:0032008=ISS, GO:0008283=TAS, GO:0035457=IDA, GO:0031100=IEA, GO:2000533=ISS, GO:0048146=IDA, GO:0046718=IDA, GO:0097028=IEP, GO:0019079=IDA, GO:0085029=ISS, GO:0032148=ISS, GO:0031093=TAS, GO:0007050=TAS, GO:0007155=TAS, GO:0071333=ISS, GO:0043154=IDA, GO:0009267=IEA, GO:0030971=IPI, GO:0043066=IDA, GO:0005245=IDA, GO:0005102=IPI, GO:0070168=IDA, GO:0005576=TAS, GO:0003104=ISS, GO:0070527=TAS, GO:0007165=IDA, GO:0017187=TAS, GO:0016477=TAS, GO:0071363=IEA, GO:0007596=TAS, GO:0002576=TAS, GO:0001934=IDA, GO:0001764=IEA, GO:2000352=IDA, GO:0046813=IDA, GO:0097241=IDA, GO:0007167=IEA} B cell chemotaxis, activation of protein kinase B activity, apoptotic cell clearance, blood coagulation, calcium ion transmembrane transport, cell adhesion, cell cycle arrest, cell migration, cell proliferation, cell-substrate adhesion, cellular protein metabolic process, cellular response to glucose stimulus, cellular response to growth factor stimulus, cellular response to interferon-alpha, cellular response to starvation, cellular response to vitamin K, dendritic cell differentiation, enzyme linked receptor protein signaling pathway, extracellular matrix assembly, hematopoietic stem cell migration to bone marrow, leukocyte migration, macrophage cytokine production, negative regulation of apoptotic process, negative regulation of biomineral tissue development, negative regulation of cysteine-type endopeptidase activity involved in apoptotic process, negative regulation of dendritic cell apoptotic process, negative regulation of endothelial cell apoptotic process, negative regulation of interleukin-6 production, negative regulation of renal albumin absorption, negative regulation of tumor necrosis factor production, negative regulation of tumor necrosis factor-mediated signaling pathway, neuron migration, organ regeneration, peptidyl-glutamic acid carboxylation, phagocytosis, platelet activation, platelet aggregation, platelet degranulation, positive regulation of ERK1 and ERK2 cascade, positive regulation of TOR signaling cascade, positive regulation of dendritic cell chemotaxis, positive regulation of fibroblast proliferation, positive regulation of glomerular filtration, positive regulation of protein kinase B signaling cascade, positive regulation of protein phosphorylation, post-translational protein modification, protein kinase B signaling cascade, proteolysis, regulation of growth, signal transduction, viral entry into host cell, viral entry into host cell via membrane fusion with the plasma membrane, viral genome replication, virion attachment, binding of host cell surface receptor Golgi lumen, endoplasmic reticulum lumen, extracellular region, extracellular space, platelet alpha granule lumen binding, bridging, calcium ion binding, cysteine-type endopeptidase inhibitor activity involved in apoptotic process, phosphatidylserine binding, protein binding, receptor agonist activity, receptor binding, receptor tyrosine kinase binding, voltage-gated calcium channel activity Human GAS7 GOC UniProtKB {GO:0006355=PMID:9736752, GO:0005737=GO_REF:0000039, GO:0003700=PMID:9736752, GO:0051015=GO_REF:0000019, GO:0048812=GO_REF:0000019, GO:0008360=GO_REF:0000019, GO:0005884=GO_REF:0000019, GO:0030041=GO_REF:0000019, GO:0007050=PMID:9736752, GO:0051017=GO_REF:0000019, GO:0001726=GO_REF:0000019} O60861 Growth arrest-specific protein 7 protein 20130413 {GO:0006355=TAS, GO:0005737=IEA, GO:0003700=TAS, GO:0051015=IEA, GO:0048812=IEA, GO:0008360=IEA, GO:0005884=IEA, GO:0030041=IEA, GO:0007050=TAS, GO:0051017=IEA, GO:0001726=IEA} actin filament bundle assembly, actin filament polymerization, cell cycle arrest, neuron projection morphogenesis, regulation of cell shape, regulation of transcription, DNA-dependent actin filament, cytoplasm, ruffle actin filament binding, sequence-specific DNA binding transcription factor activity Human GAS8 PINC UniProtKB {GO:0003674=GO_REF:0000015, GO:0017137=GO_REF:0000019, GO:0008285=PMID:9790751, GO:0005794=GO_REF:0000039, GO:0031514=GO_REF:0000024, GO:0005874=PMID:10969087, GO:0005932=GO_REF:0000039, GO:0034613=GO_REF:0000019, GO:0030317=GO_REF:0000024} O95995 Growth arrest-specific protein 8 protein 20030904 {GO:0003674=ND, GO:0017137=IEA, GO:0008285=TAS, GO:0005794=IEA, GO:0031514=ISS, GO:0005874=IDA, GO:0005932=IEA, GO:0034613=IEA, GO:0030317=ISS} cellular protein localization, negative regulation of cell proliferation, sperm motility Golgi apparatus, microtubule, microtubule basal body, motile cilium Rab GTPase binding, molecular_function Human GAST Reactome UniProtKB {GO:0007165=PMID:7488110, GO:0007186=GO_REF:0000019, GO:0005179=GO_REF:0000019, GO:0005576=Reactome:REACT_121113} P01350 Gastrin protein 20100607 {GO:0007165=NAS, GO:0007186=IEA, GO:0005179=IEA, GO:0005576=TAS} G-protein coupled receptor signaling pathway, signal transduction extracellular region hormone activity Human GATA1 HPA UniProtKB {GO:0005515=PMID:11418466, GO:0097067=PMID:19375645, GO:0008285=GO_REF:0000019, GO:0003700=PMID:2467208, GO:0006366=PMID:2467208, GO:0071733=GO_REF:0000024, GO:0007267=GO_REF:0000019, GO:0050731=PMID:15701726, GO:0005634=GO_REF:0000052, GO:0097028=GO_REF:0000019, GO:2000678=PMID:15920471, GO:0002039=GO_REF:0000019, GO:0048821=PMID:10700180, GO:0045944=PMID:12200364, GO:0017053=PMID:15920471, GO:0001085=PMID:15920471, GO:0030222=PMID:8507862, GO:0033690=GO_REF:0000019, GO:0030221=PMID:7678994, GO:0035162=GO_REF:0000019, GO:0030220=PMID:10700180, GO:0005667=PMID:15920471, GO:0031965=GO_REF:0000052, GO:0043066=PMID:15967790, GO:0000976=PMID:10700180, GO:0010559=PMID:15701726, GO:0000977=PMID:2467208, GO:0008301=GO_REF:0000019, GO:0005730=GO_REF:0000052, GO:0000978=GO_REF:0000019, GO:0030502=GO_REF:0000019, GO:0001701=GO_REF:0000019, GO:0003677=PMID:11418466, GO:0010724=PMID:12200364, GO:0070527=PMID:15701726, GO:0043565=PMID:12200364, GO:0001078=PMID:15920471, GO:0001077=GO_REF:0000019, GO:0035854=PMID:12045236, GO:0007596=Reactome:REACT_604, GO:0030219=PMID:10700180, GO:0003682=GO_REF:0000019, GO:0030218=PMID:7678994, GO:0070742=PMID:12483298, GO:0008270=GO_REF:0000002, GO:0005654=Reactome:REACT_25215, GO:0001158=GO_REF:0000019, GO:0008584=PMID:10700180} P15976 Erythroid transcription factor protein 20101115 {GO:0005515=IPI, GO:0097067=IDA, GO:0008285=IEA, GO:0003700=IDA, GO:0006366=IDA, GO:0071733=ISS, GO:0007267=IEA, GO:0050731=IMP, GO:0005634=IDA, GO:0097028=IEA, GO:2000678=IDA, GO:0002039=IEA, GO:0048821=IMP, GO:0045944=IDA, GO:0017053=IDA, GO:0001085=IPI, GO:0030222=IEP, GO:0033690=IEA, GO:0030221=IEP, GO:0035162=IEA, GO:0030220=IMP, GO:0005667=IDA, GO:0031965=IDA, GO:0043066=TAS, GO:0000976=IMP, GO:0010559=IMP, GO:0000977=IDA, GO:0008301=IEA, GO:0005730=IDA, GO:0000978=IEA, GO:0030502=IEA, GO:0001701=IEA, GO:0003677=IDA, GO:0010724=IDA, GO:0070527=IMP, GO:0043565=IMP, GO:0001078=IDA, GO:0001077=IEA, GO:0035854=IDA, GO:0007596=TAS, GO:0030219=IMP, GO:0003682=IEA, GO:0030218=IEP, GO:0070742=IPI, GO:0008270=IEA, GO:0005654=TAS, GO:0001158=IEA, GO:0008584=IMP} basophil differentiation, blood coagulation, cell-cell signaling, cellular response to thyroid hormone stimulus, dendritic cell differentiation, embryonic hemopoiesis, eosinophil differentiation, eosinophil fate commitment, erythrocyte development, erythrocyte differentiation, in utero embryonic development, male gonad development, megakaryocyte differentiation, negative regulation of apoptotic process, negative regulation of bone mineralization, negative regulation of cell proliferation, negative regulation of transcription regulatory region DNA binding, platelet aggregation, platelet formation, positive regulation of osteoblast proliferation, positive regulation of peptidyl-tyrosine phosphorylation, positive regulation of transcription from RNA polymerase II promoter, regulation of definitive erythrocyte differentiation, regulation of glycoprotein biosynthetic process, transcription from RNA polymerase II promoter, transcriptional activation by promoter-enhancer looping nuclear membrane, nucleolus, nucleoplasm, nucleus, transcription factor complex, transcriptional repressor complex C2H2 zinc finger domain binding, DNA binding, DNA binding, bending, RNA polymerase II core promoter proximal region sequence-specific DNA binding, RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription, RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription, RNA polymerase II regulatory region sequence-specific DNA binding, RNA polymerase II transcription factor binding, chromatin binding, enhancer sequence-specific DNA binding, p53 binding, protein binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, transcription regulatory region sequence-specific DNA binding, zinc ion binding Human GATA2 HPA UniProtKB {GO:0005515=PMID:21988832, GO:0021514=GO_REF:0000019, GO:0006909=GO_REF:0000019, GO:0021533=GO_REF:0000019, GO:0003700=PMID:15016828, GO:0045599=PMID:20705609, GO:0021983=GO_REF:0000019, GO:0001655=GO_REF:0000019, GO:0070345=PMID:20705609, GO:0005634=GO_REF:0000052, GO:0035065=GO_REF:0000019, GO:0060872=GO_REF:0000019, GO:0050766=GO_REF:0000024, GO:0045654=GO_REF:0000019, GO:0048873=GO_REF:0000019, GO:0045944=PMID:15016828, GO:0048469=GO_REF:0000019, GO:0035019=GO_REF:0000019, GO:0045746=PMID:16672344, GO:2000178=PMID:16672344, GO:0042472=GO_REF:0000019, GO:0001709=GO_REF:0000019, GO:0005730=GO_REF:0000052, GO:0021954=GO_REF:0000019, GO:0001892=GO_REF:0000019, GO:0060216=GO_REF:0000019, GO:0000122=GO_REF:0000019, GO:0048663=GO_REF:0000019, GO:0045650=GO_REF:0000019, GO:0006351=PMID:16153155, GO:0045766=PMID:19242469, GO:0043234=GO_REF:0000019, GO:0001077=GO_REF:0000019, GO:0035854=PMID:12045236, GO:0007596=Reactome:REACT_604, GO:0045648=GO_REF:0000019, GO:0003682=PMID:19242469, GO:0070742=PMID:12483298, GO:0005654=Reactome:REACT_25215, GO:0008270=GO_REF:0000002, GO:0000980=GO_REF:0000019, GO:0001158=PMID:19323994, GO:0008134=PMID:15016828} P23769 Endothelial transcription factor GATA-2 protein 20111111 {GO:0005515=IPI, GO:0021514=IEA, GO:0006909=IEA, GO:0021533=IEA, GO:0003700=IDA, GO:0045599=IMP, GO:0021983=IEA, GO:0001655=IEA, GO:0070345=IMP, GO:0005634=IDA, GO:0035065=IEA, GO:0060872=IEA, GO:0050766=ISS, GO:0045654=IEA, GO:0048873=IEA, GO:0045944=IDA, GO:0048469=IEA, GO:0035019=IEA, GO:0045746=IDA, GO:2000178=IDA, GO:0042472=IEA, GO:0001709=IEA, GO:0005730=IDA, GO:0021954=IEA, GO:0001892=IEA, GO:0060216=IEA, GO:0000122=IEA, GO:0048663=IEA, GO:0045650=IEA, GO:0006351=IDA, GO:0045766=IDA, GO:0043234=IEA, GO:0001077=IEA, GO:0035854=IDA, GO:0007596=TAS, GO:0045648=IEA, GO:0003682=IDA, GO:0070742=IPI, GO:0005654=TAS, GO:0008270=IEA, GO:0000980=IEA, GO:0001158=IDA, GO:0008134=IPI} blood coagulation, cell differentiation in hindbrain, cell fate determination, cell maturation, central nervous system neuron development, definitive hemopoiesis, embryonic placenta development, eosinophil fate commitment, homeostasis of number of cells within a tissue, inner ear morphogenesis, negative regulation of Notch signaling pathway, negative regulation of fat cell differentiation, negative regulation of fat cell proliferation, negative regulation of macrophage differentiation, negative regulation of neural precursor cell proliferation, negative regulation of transcription from RNA polymerase II promoter, neuron fate commitment, phagocytosis, pituitary gland development, positive regulation of angiogenesis, positive regulation of erythrocyte differentiation, positive regulation of megakaryocyte differentiation, positive regulation of phagocytosis, positive regulation of transcription from RNA polymerase II promoter, regulation of histone acetylation, semicircular canal development, somatic stem cell maintenance, transcription, DNA-dependent, urogenital system development, ventral spinal cord interneuron differentiation nucleolus, nucleoplasm, nucleus, protein complex C2H2 zinc finger domain binding, RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription, RNA polymerase II distal enhancer sequence-specific DNA binding, chromatin binding, enhancer sequence-specific DNA binding, protein binding, sequence-specific DNA binding transcription factor activity, transcription factor binding, zinc ion binding NOT Human GATA3 BHF-UCL UniProtKB {GO:0071773=GO_REF:0000019, GO:0005515=PMID:19723756, GO:0032753=GO_REF:0000024, GO:0043627=PMID:10037815, GO:0003700=PMID:2050118, GO:0032754=GO_REF:0000019, GO:0044212=PMID:19735555, GO:2000146=PMID:20189993, GO:0009791=GO_REF:0000019, GO:0009653=PMID:10935639, GO:0072182=GO_REF:0000024, GO:0048589=GO_REF:0000019, GO:0048646=GO_REF:0000024, GO:0072179=GO_REF:0000024, GO:0072178=GO_REF:0000024, GO:0046983=GO_REF:0000019, GO:2000611=PMID:19248180, GO:0010332=GO_REF:0000019, GO:0031929=GO_REF:0000024, GO:0035799=GO_REF:0000019, GO:0042472=GO_REF:0000019, GO:0001709=GO_REF:0000024, GO:0003713=PMID:20484083, GO:0060231=PMID:20189993, GO:0072107=GO_REF:0000024, GO:0006952=PMID:7592673, GO:0001701=GO_REF:0000019, GO:0035898=GO_REF:0000019, GO:0001806=GO_REF:0000019, GO:0060037=GO_REF:0000024, GO:0010595=PMID:19674970, GO:0072643=GO_REF:0000019, GO:0008270=GO_REF:0000002, GO:0008134=PMID:15016828, GO:0050852=GO_REF:0000024, GO:0060065=GO_REF:0000024, GO:2000679=PMID:20368097, GO:0045471=GO_REF:0000019, GO:0005634=GO_REF:0000052, GO:0032736=GO_REF:0000019, GO:0002088=GO_REF:0000019, GO:0006959=GO_REF:0000019, GO:0048469=GO_REF:0000019, GO:0001046=PMID:19674970, GO:2000703=GO_REF:0000024, GO:0071599=GO_REF:0000019, GO:0001822=PMID:19248180, GO:0042493=GO_REF:0000019, GO:0001823=GO_REF:0000024, GO:0061085=GO_REF:0000019, GO:2000114=GO_REF:0000019, GO:2000683=PMID:19735555, GO:0009615=PMID:20583921, GO:0007596=Reactome:REACT_604, GO:0045064=GO_REF:0000019, GO:2000607=GO_REF:0000024, GO:0045061=GO_REF:0000019, GO:0050728=PMID:19674970, GO:0030218=GO_REF:0000019, GO:0042421=GO_REF:0000024, GO:0001764=GO_REF:0000019, GO:0000987=PMID:19232384, GO:0000790=PMID:20855495, GO:0006366=PMID:1871134, GO:0003180=GO_REF:0000024, GO:0045599=PMID:20705609, GO:0048538=GO_REF:0000019, GO:0003281=GO_REF:0000024, GO:0060676=GO_REF:0000024, GO:0043523=GO_REF:0000019, GO:0060374=GO_REF:0000019, GO:0007411=GO_REF:0000019, GO:0071356=PMID:19674970, GO:0071353=PMID:20554961, GO:0032689=GO_REF:0000019, GO:2000664=PMID:20554961, GO:0000976=PMID:19723756, GO:2000667=PMID:20368097, GO:0070888=PMID:20855495, GO:0045786=PMID:20189993, GO:0072676=PMID:19805038, GO:0000979=GO_REF:0000019, GO:0014065=GO_REF:0000024, GO:0048485=GO_REF:0000024, GO:0002572=GO_REF:0000019, GO:0071837=PMID:18445004, GO:0005654=Reactome:REACT_25215, GO:0072602=GO_REF:0000019, GO:0045893=PMID:19723756, GO:0001158=GO_REF:0000019, GO:0045892=PMID:19674970, GO:0051897=PMID:19674970, GO:0008285=GO_REF:0000024, GO:0005134=GO_REF:0000019, GO:0035457=PMID:20554961, GO:0003215=GO_REF:0000024, GO:2000734=GO_REF:0000024, GO:0043583=PMID:19248180, GO:0045944=PMID:20855495, GO:0051569=GO_REF:0000019, GO:0035162=GO_REF:0000019, GO:0045582=GO_REF:0000024, GO:0032703=GO_REF:0000019, GO:0005730=GO_REF:0000052, GO:0009967=PMID:19674970, GO:0003677=PMID:1871134, GO:0043370=GO_REF:0000019, GO:0042035=GO_REF:0000024, GO:0001078=PMID:19674970, GO:0007165=GO_REF:0000024, GO:0060017=GO_REF:0000019, GO:0001077=GO_REF:0000019, GO:0061290=GO_REF:0000024, GO:0001071=PMID:19674970, GO:2000352=PMID:19674970, GO:0033600=PMID:19483726, GO:0008584=GO_REF:0000024} P23771 Trans-acting T-cell-specific transcription factor GATA-3 protein 20110205 {GO:0071773=IEA, GO:0005515=IPI, GO:0032753=ISS, GO:0043627=IEP, GO:0003700=TAS, GO:0032754=IEA, GO:0044212=IDA, GO:2000146=IMP, GO:0009791=IEA, GO:0009653=TAS, GO:0072182=ISS, GO:0048589=IEA, GO:0048646=ISS, GO:0072179=ISS, GO:0072178=ISS, GO:0046983=IEA, GO:2000611=IMP, GO:0010332=IEA, GO:0031929=ISS, GO:0035799=IEA, GO:0042472=IEA, GO:0001709=ISS, GO:0003713=IDA, GO:0060231=IDA, GO:0072107=ISS, GO:0006952=TAS, GO:0001701=IEA, GO:0035898=IEA, GO:0001806=IEA, GO:0060037=ISS, GO:0010595=IMP, GO:0072643=IEA, GO:0008270=IEA, GO:0008134=IPI, GO:0050852=ISS, GO:0060065=ISS, GO:2000679=IMP, GO:0045471=IEA, GO:0005634=IDA, GO:0032736=IEA, GO:0002088=IEA, GO:0006959=IEA, GO:0048469=IEA, GO:0001046=IDA, GO:2000703=ISS, GO:0071599=IEA, GO:0001822=IMP, GO:0042493=IEA, GO:0001823=ISS, GO:0061085=IEA, GO:2000114=IEA, GO:2000683=IMP, GO:0009615=IEP, GO:0007596=TAS, GO:0045064=IEA, GO:2000607=ISS, GO:0045061=IEA, GO:0050728=IMP, GO:0030218=IEA, GO:0042421=ISS, GO:0001764=IEA, GO:0000987=IDA, GO:0000790=IDA, GO:0006366=TAS, GO:0003180=ISS, GO:0045599=IMP, GO:0048538=IEA, GO:0003281=ISS, GO:0060676=ISS, GO:0043523=IEA, GO:0060374=IEA, GO:0007411=IEA, GO:0071356=IEP, GO:0071353=IEP, GO:0032689=IEA, GO:2000664=IDA, GO:0000976=IDA, GO:2000667=IMP, GO:0070888=IDA, GO:0045786=IMP, GO:0072676=IDA, GO:0000979=IEA, GO:0014065=ISS, GO:0048485=ISS, GO:0002572=IEA, GO:0071837=IPI, GO:0005654=TAS, GO:0072602=IEA, GO:0045893=IDA, GO:0001158=IEA, GO:0045892=IMP, GO:0051897=IMP, GO:0008285=ISS, GO:0005134=IEA, GO:0035457=IEP, GO:0003215=ISS, GO:2000734=ISS, GO:0043583=IMP, GO:0045944=IMP, GO:0051569=IEA, GO:0035162=IEA, GO:0045582=ISS, GO:0032703=IEA, GO:0005730=IDA, GO:0009967=IMP, GO:0003677=TAS, GO:0043370=IEA, GO:0042035=ISS, GO:0001078=IMP, GO:0007165=ISS, GO:0060017=IEA, GO:0001077=IEA, GO:0061290=ISS, GO:0001071=IMP, GO:2000352=IMP, GO:0033600=IDA, GO:0008584=ISS} T cell receptor signaling pathway, T-helper 2 cell differentiation, TOR signaling cascade, anatomical structure formation involved in morphogenesis, anatomical structure morphogenesis, aortic valve morphogenesis, axon guidance, blood coagulation, canonical Wnt receptor signaling pathway involved in metanephric kidney development, cardiac right ventricle morphogenesis, cell fate determination, cell maturation, cellular response to BMP stimulus, cellular response to interferon-alpha, cellular response to interleukin-4, cellular response to tumor necrosis factor, defense response, developmental growth, ear development, embryonic hemopoiesis, erythrocyte differentiation, humoral immune response, in utero embryonic development, inner ear morphogenesis, interferon-gamma secretion, interleukin-4 secretion, kidney development, lens development in camera-type eye, lymphocyte migration, male gonad development, mast cell differentiation, mesenchymal to epithelial transition, mesonephros development, negative regulation of cell cycle, negative regulation of cell motility, negative regulation of cell proliferation, negative regulation of cell proliferation involved in mesonephros development, negative regulation of endothelial cell apoptotic process, negative regulation of fat cell differentiation, negative regulation of fibroblast growth factor receptor signaling pathway involved in ureteric bud formation, negative regulation of glial cell-derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation, negative regulation of inflammatory response, negative regulation of interferon-gamma production, negative regulation of interleukin-2 production, negative regulation of mammary gland epithelial cell proliferation, negative regulation of transcription, DNA-dependent, nephric duct formation, nephric duct morphogenesis, neuron migration, norepinephrine biosynthetic process, otic vesicle development, parathyroid gland development, parathyroid hormone secretion, pharyngeal system development, phosphatidylinositol 3-kinase cascade, positive regulation of T cell differentiation, positive regulation of endothelial cell migration, positive regulation of interleukin-13 production, positive regulation of interleukin-13 secretion, positive regulation of interleukin-4 production, positive regulation of interleukin-5 production, positive regulation of interleukin-5 secretion, positive regulation of protein kinase B signaling cascade, positive regulation of signal transduction, positive regulation of thyroid hormone generation, positive regulation of transcription from RNA polymerase II promoter, positive regulation of transcription regulatory region DNA binding, positive regulation of transcription, DNA-dependent, positive regulation of ureteric bud formation, post-embryonic development, pro-T cell differentiation, regulation of CD4-positive, alpha-beta T cell differentiation, regulation of cellular response to X-ray, regulation of cytokine biosynthetic process, regulation of establishment of cell polarity, regulation of histone H3-K27 methylation, regulation of histone H3-K4 methylation, regulation of nephron tubule epithelial cell differentiation, regulation of neuron apoptotic process, response to drug, response to estrogen stimulus, response to ethanol, response to gamma radiation, response to virus, signal transduction, sympathetic nervous system development, thymic T cell selection, thymus development, transcription from RNA polymerase II promoter, type IV hypersensitivity, ureter maturation, ureteric bud formation, uterus development, ventricular septum development nuclear chromatin, nucleolus, nucleoplasm, nucleus DNA binding, E-box binding, HMG box domain binding, RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription, RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription, RNA polymerase II core promoter sequence-specific DNA binding, core promoter proximal region sequence-specific DNA binding, core promoter sequence-specific DNA binding, enhancer sequence-specific DNA binding, interleukin-2 receptor binding, nucleic acid binding transcription factor activity, protein binding, protein dimerization activity, sequence-specific DNA binding transcription factor activity, transcription coactivator activity, transcription factor binding, transcription regulatory region DNA binding, transcription regulatory region sequence-specific DNA binding, zinc ion binding Human GATA4 BHF-UCL UniProtKB {GO:0060045=GO_REF:0000019, GO:0005515=PMID:9312027, GO:0003289=GO_REF:0000024, GO:0043627=GO_REF:0000019, GO:0003700=PMID:9312027, GO:0006366=GO_REF:0000024, GO:0044212=PMID:9566909, GO:0003181=GO_REF:0000019, GO:0003705=GO_REF:0000019, GO:0003281=GO_REF:0000024, GO:0007283=GO_REF:0000019, GO:0060575=PMID:9566909, GO:0001947=GO_REF:0000024, GO:0060008=GO_REF:0000019, GO:0061049=GO_REF:0000019, GO:0055007=PMID:9857019, GO:0003229=GO_REF:0000019, GO:0001706=GO_REF:0000019, GO:0000977=GO_REF:0000019, GO:0023019=GO_REF:0000019, GO:0030509=GO_REF:0000019, GO:0001701=GO_REF:0000019, GO:0001702=GO_REF:0000019, GO:0072148=GO_REF:0000019, GO:0035239=GO_REF:0000019, GO:0010507=GO_REF:0000019, GO:0008270=GO_REF:0000002, GO:0005654=Reactome:REACT_25215, GO:0045893=GO_REF:0000024, GO:0001158=GO_REF:0000019, GO:0008134=PMID:9858576, GO:0051525=GO_REF:0000019, GO:0007267=GO_REF:0000024, GO:0003215=GO_REF:0000024, GO:0005634=GO_REF:0000024, GO:0051891=GO_REF:0000024, GO:0060395=GO_REF:0000019, GO:0071372=GO_REF:0000019, GO:0030513=GO_REF:0000019, GO:0045944=GO_REF:0000024, GO:0033613=GO_REF:0000024, GO:0071333=GO_REF:0000019, GO:0060070=GO_REF:0000019, GO:0006355=GO_REF:0000024, GO:0060413=PMID:12845333, GO:0003197=PMID:21330551, GO:0042493=PMID:20585342, GO:0070410=PMID:21330551, GO:0035054=GO_REF:0000024, GO:0003208=PMID:20347099, GO:0010575=GO_REF:0000024, GO:0003677=GO_REF:0000024, GO:0045766=GO_REF:0000024, GO:0003290=PMID:20347099, GO:0009612=GO_REF:0000019, GO:0043565=GO_REF:0000024, GO:0001076=PMID:21330551, GO:0007492=PMID:20347099, GO:0048557=GO_REF:0000019, GO:0060464=GO_REF:0000019, GO:0007596=Reactome:REACT_604, GO:0003682=GO_REF:0000019, GO:0072520=GO_REF:0000019, GO:0048617=GO_REF:0000024, GO:0008584=PMID:17848411} P43694 Transcription factor GATA-4 protein 20121129 {GO:0060045=IEA, GO:0005515=IPI, GO:0003289=ISS, GO:0043627=IEA, GO:0003700=IDA, GO:0006366=ISS, GO:0044212=IDA, GO:0003181=IEA, GO:0003705=IEA, GO:0003281=ISS, GO:0007283=IEA, GO:0060575=IDA, GO:0001947=ISS, GO:0060008=IEA, GO:0061049=IEA, GO:0055007=IEP, GO:0003229=IEA, GO:0001706=IEA, GO:0000977=IEA, GO:0023019=IEA, GO:0030509=IEA, GO:0001701=IEA, GO:0001702=IEA, GO:0072148=IEA, GO:0035239=IEA, GO:0010507=IEA, GO:0008270=IEA, GO:0005654=TAS, GO:0045893=ISS, GO:0001158=IEA, GO:0008134=IPI, GO:0051525=IEA, GO:0007267=ISS, GO:0003215=ISS, GO:0005634=ISS, GO:0051891=ISS, GO:0060395=IEA, GO:0071372=IEA, GO:0030513=IEA, GO:0045944=ISS, GO:0033613=ISS, GO:0071333=IEA, GO:0060070=IEA, GO:0006355=ISS, GO:0060413=IMP, GO:0003197=IMP, GO:0042493=IMP, GO:0070410=IPI, GO:0035054=ISS, GO:0003208=TAS, GO:0010575=ISS, GO:0003677=ISS, GO:0045766=ISS, GO:0003290=IMP, GO:0009612=IEA, GO:0043565=ISS, GO:0001076=IDA, GO:0007492=TAS, GO:0048557=IEA, GO:0060464=IEA, GO:0007596=TAS, GO:0003682=IEA, GO:0072520=IEA, GO:0048617=ISS, GO:0008584=IEP} BMP signaling pathway, SMAD protein signal transduction, Sertoli cell differentiation, atrial septum morphogenesis, atrial septum primum morphogenesis, atrial septum secundum morphogenesis, atrioventricular valve morphogenesis, blood coagulation, canonical Wnt receptor signaling pathway, cardiac muscle cell differentiation, cardiac right ventricle morphogenesis, cardiac ventricle morphogenesis, cell growth involved in cardiac muscle cell development, cell-cell signaling, cellular response to follicle-stimulating hormone stimulus, cellular response to glucose stimulus, embryonic digestive tract morphogenesis, embryonic foregut morphogenesis, embryonic heart tube anterior/posterior pattern specification, endocardial cushion development, endoderm development, endoderm formation, epithelial cell fate commitment, gastrulation with mouth forming second, heart looping, in utero embryonic development, intestinal epithelial cell differentiation, lung lobe formation, male gonad development, negative regulation of autophagy, positive regulation of BMP signaling pathway, positive regulation of angiogenesis, positive regulation of cardiac muscle cell proliferation, positive regulation of cardioblast differentiation, positive regulation of transcription from RNA polymerase II promoter, positive regulation of transcription, DNA-dependent, positive regulation vascular endothelial growth factor production, regulation of transcription, DNA-dependent, response to drug, response to estrogen stimulus, response to mechanical stimulus, seminiferous tubule development, signal transduction involved in regulation of gene expression, spermatogenesis, transcription from RNA polymerase II promoter, tube morphogenesis, ventricular cardiac muscle tissue development, ventricular septum development nucleoplasm, nucleus DNA binding, NFAT protein binding, RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity, RNA polymerase II regulatory region sequence-specific DNA binding, RNA polymerase II transcription factor binding transcription factor activity, activating transcription factor binding, chromatin binding, co-SMAD binding, enhancer sequence-specific DNA binding, protein binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, transcription factor binding, transcription regulatory region DNA binding, zinc ion binding Human GATA5 Reactome UniProtKB {GO:0071773=GO_REF:0000019, GO:0003700=PMID:14986113, GO:0044212=PMID:9566909, GO:0007596=Reactome:REACT_604, GO:0045944=PMID:14986113, GO:0003705=GO_REF:0000019, GO:0005654=Reactome:REACT_25215, GO:0005634=PMID:9566909, GO:0008270=GO_REF:0000002, GO:0001158=GO_REF:0000019, GO:0060575=PMID:9566909} Q9BWX5 Transcription factor GATA-5 protein 20130301 {GO:0071773=IEA, GO:0003700=IDA, GO:0044212=IDA, GO:0007596=TAS, GO:0045944=IDA, GO:0003705=IEA, GO:0005654=TAS, GO:0005634=IDA, GO:0008270=IEA, GO:0001158=IEA, GO:0060575=IDA} blood coagulation, cellular response to BMP stimulus, intestinal epithelial cell differentiation, positive regulation of transcription from RNA polymerase II promoter nucleoplasm, nucleus RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity, enhancer sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, transcription regulatory region DNA binding, zinc ion binding Human GATA6 BHF-UCL UniProtKB {GO:0071773=GO_REF:0000019, GO:0060045=GO_REF:0000019, GO:0005515=PMID:16199874, GO:0043627=GO_REF:0000019, GO:0003700=PMID:19666519, GO:0044212=PMID:19666519, GO:0006366=PMID:19666519, GO:0003705=GO_REF:0000019, GO:0000981=PMID:21127043, GO:0003310=GO_REF:0000019, GO:0032911=PMID:21127043, GO:0032912=PMID:21127043, GO:0071158=PMID:9593712, GO:0060575=PMID:9566909, GO:0048645=GO_REF:0000019, GO:0060430=GO_REF:0000019, GO:0003309=GO_REF:0000019, GO:0055007=GO_REF:0000019, GO:0001103=GO_REF:0000019, GO:0019901=PMID:20864106, GO:0000122=PMID:18177748, GO:0070848=PMID:21127043, GO:0000979=GO_REF:0000019, GO:0001701=GO_REF:0000019, GO:0001889=GO_REF:0000019, GO:0035239=GO_REF:0000019, GO:0060486=GO_REF:0000019, GO:0008270=GO_REF:0000002, GO:0005654=Reactome:REACT_25215, GO:0006644=GO_REF:0000019, GO:0045892=PMID:18177748, GO:0051145=PMID:17626241, GO:0008134=PMID:15016828, GO:0005634=PMID:19666519, GO:0051891=GO_REF:0000019, GO:0071371=GO_REF:0000019, GO:0045944=GO_REF:0000019, GO:0005667=GO_REF:0000019, GO:0043066=PMID:21127043, GO:0042493=PMID:18671946, GO:0006915=GO_REF:0000019, GO:0071456=PMID:21127043, GO:0045766=PMID:21127043, GO:0007493=GO_REF:0000019, GO:0060947=PMID:11889139, GO:0007596=Reactome:REACT_604, GO:0003682=GO_REF:0000019, GO:0003148=PMID:19666519, GO:0060510=GO_REF:0000019, GO:0008584=PMID:17848411} Q92908 Transcription factor GATA-6 protein 20080306 {GO:0071773=IEA, GO:0060045=IEA, GO:0005515=IPI, GO:0043627=IEA, GO:0003700=IDA, GO:0044212=IDA, GO:0006366=IDA, GO:0003705=IEA, GO:0000981=IMP, GO:0003310=IEA, GO:0032911=IMP, GO:0032912=IMP, GO:0071158=IDA, GO:0060575=IDA, GO:0048645=IEA, GO:0060430=IEA, GO:0003309=IEA, GO:0055007=IEA, GO:0001103=IEA, GO:0019901=IPI, GO:0000122=IDA, GO:0070848=IDA, GO:0000979=IEA, GO:0001701=IEA, GO:0001889=IEA, GO:0035239=IEA, GO:0060486=IEA, GO:0008270=IEA, GO:0005654=TAS, GO:0006644=IEA, GO:0045892=IDA, GO:0051145=IMP, GO:0008134=IPI, GO:0005634=IDA, GO:0051891=IEA, GO:0071371=IEA, GO:0045944=IEA, GO:0005667=IEA, GO:0043066=IMP, GO:0042493=IMP, GO:0006915=IEA, GO:0071456=IDA, GO:0045766=IDA, GO:0007493=IEA, GO:0060947=IMP, GO:0007596=TAS, GO:0003682=IEA, GO:0003148=IMP, GO:0060510=IEA, GO:0008584=IEP} Clara cell differentiation, Type II pneumocyte differentiation, apoptotic process, blood coagulation, cardiac muscle cell differentiation, cardiac vascular smooth muscle cell differentiation, cellular response to BMP stimulus, cellular response to gonadotropin stimulus, cellular response to hypoxia, endodermal cell fate determination, in utero embryonic development, intestinal epithelial cell differentiation, liver development, lung saccule development, male gonad development, negative regulation of apoptotic process, negative regulation of transcription from RNA polymerase II promoter, negative regulation of transcription, DNA-dependent, negative regulation of transforming growth factor beta1 production, negative regulation of transforming growth factor beta2 production, organ formation, outflow tract septum morphogenesis, pancreatic A cell differentiation, phospholipid metabolic process, positive regulation of angiogenesis, positive regulation of cardiac muscle cell proliferation, positive regulation of cardioblast differentiation, positive regulation of cell cycle arrest, positive regulation of transcription from RNA polymerase II promoter, response to drug, response to estrogen stimulus, response to growth factor stimulus, smooth muscle cell differentiation, transcription from RNA polymerase II promoter, tube morphogenesis, type B pancreatic cell differentiation nucleoplasm, nucleus, transcription factor complex RNA polymerase II core promoter sequence-specific DNA binding, RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity, RNA polymerase II repressing transcription factor binding, chromatin binding, protein binding, protein kinase binding, sequence-specific DNA binding RNA polymerase II transcription factor activity, sequence-specific DNA binding transcription factor activity, transcription factor binding, transcription regulatory region DNA binding, zinc ion binding Human UniProtKB:Q03014 GATAD1 UniProtKB UniProtKB {GO:0043565=GO_REF:0000002, GO:0003700=GO_REF:0000002, GO:0005634=PMID:21965549, GO:0008270=GO_REF:0000002} Q8WUU5 GATA zinc finger domain-containing protein 1 protein 20120821 {GO:0043565=IEA, GO:0003700=IEA, GO:0005634=IDA, GO:0008270=IEA} nucleus sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, zinc ion binding Human GATAD2A HPA UniProtKB {GO:0005515=PMID:12183469, GO:0010172=GO_REF:0000019, GO:0003700=GO_REF:0000002, GO:0001568=GO_REF:0000019, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0012501=GO_REF:0000019, GO:0001701=GO_REF:0000019, GO:0001842=GO_REF:0000019, GO:0006351=GO_REF:0000037, GO:0021506=GO_REF:0000019, GO:0006306=PMID:12183469, GO:0043565=GO_REF:0000002, GO:0016581=PMID:12183469, GO:0016607=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0030674=PMID:12183469, GO:0045892=PMID:12183469} Q86YP4 Transcriptional repressor p66-alpha protein 20080205 {GO:0005515=IPI, GO:0010172=IEA, GO:0003700=IEA, GO:0001568=IEA, GO:0005730=IDA, GO:0005634=IDA, GO:0012501=IEA, GO:0001701=IEA, GO:0001842=IEA, GO:0006351=IEA, GO:0021506=IEA, GO:0006306=TAS, GO:0043565=IEA, GO:0016581=IDA, GO:0016607=IEA, GO:0008270=IEA, GO:0030674=IDA, GO:0045892=IDA} DNA methylation, anterior neuropore closure, blood vessel development, embryonic body morphogenesis, in utero embryonic development, negative regulation of transcription, DNA-dependent, neural fold formation, programmed cell death, transcription, DNA-dependent NuRD complex, nuclear speck, nucleolus, nucleus protein binding, protein binding, bridging, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, zinc ion binding NOT Human GATAD2B HPA UniProtKB {GO:0043565=GO_REF:0000002, GO:0003700=GO_REF:0000002, GO:0016607=GO_REF:0000039, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0008270=GO_REF:0000002, GO:0006351=GO_REF:0000037} Q8WXI9 Transcriptional repressor p66-beta protein 20090616 {GO:0043565=IEA, GO:0003700=IEA, GO:0016607=IEA, GO:0005730=IDA, GO:0005634=IDA, GO:0008270=IEA, GO:0006351=IEA} transcription, DNA-dependent nuclear speck, nucleolus, nucleus sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, zinc ion binding NOT Human GATC UniProtKB UniProtKB {GO:0005739=PMID:19805282, GO:0032543=PMID:19805282, GO:0050567=PMID:19805282, GO:0030956=PMID:19805282, GO:0070681=PMID:19805282, GO:0006450=GO_REF:0000002, GO:0005524=GO_REF:0000037} O43716 Glutamyl-tRNA(Gln) amidotransferase subunit C, mitochondrial protein 20110818 {GO:0005739=IDA, GO:0032543=IMP, GO:0050567=IDA, GO:0030956=IDA, GO:0070681=IDA, GO:0006450=IEA, GO:0005524=IEA} glutaminyl-tRNAGln biosynthesis via transamidation, mitochondrial translation, regulation of translational fidelity glutamyl-tRNA(Gln) amidotransferase complex, mitochondrion ATP binding, glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity Human GATM Reactome UniProtKB {GO:0015067=GO_REF:0000019, GO:0007584=GO_REF:0000019, GO:0016813=GO_REF:0000002, GO:0015068=Reactome:REACT_396, GO:0005743=GO_REF:0000039, GO:0043434=GO_REF:0000019, GO:0044281=Reactome:REACT_111217, GO:0009790=GO_REF:0000019, GO:0042246=GO_REF:0000019, GO:0005739=GO_REF:0000019, GO:0034641=Reactome:REACT_13, GO:0005758=Reactome:REACT_396, GO:0006601=PMID:9218780, GO:0006600=Reactome:REACT_813, GO:0006979=GO_REF:0000019, GO:0046689=GO_REF:0000019} P50440 Glycine amidinotransferase, mitochondrial protein 20130213 {GO:0015067=IEA, GO:0007584=IEA, GO:0016813=IEA, GO:0015068=TAS, GO:0005743=IEA, GO:0043434=IEA, GO:0044281=TAS, GO:0009790=IEA, GO:0042246=IEA, GO:0005739=IEA, GO:0034641=TAS, GO:0005758=TAS, GO:0006601=IDA, GO:0006600=TAS, GO:0006979=IEA, GO:0046689=IEA} cellular nitrogen compound metabolic process, creatine biosynthetic process, creatine metabolic process, embryo development, response to mercury ion, response to nutrient, response to oxidative stress, response to peptide hormone stimulus, small molecule metabolic process, tissue regeneration mitochondrial inner membrane, mitochondrial intermembrane space, mitochondrion amidinotransferase activity, glycine amidinotransferase activity, hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines Human GATSL1 null null {} null null null null {} null null null GATSL2 null null {} null null null null {} null null null GBA BHF-UCL UniProtKB {GO:0006665=Reactome:REACT_19323, GO:0008219=GO_REF:0000037, GO:0006687=Reactome:REACT_116105, GO:0005975=GO_REF:0000002, GO:0032715=PMID:19279008, GO:0035307=PMID:19279008, GO:0005102=PMID:18022370, GO:0004348=PMID:19279011, GO:0044281=Reactome:REACT_111217, GO:0005765=PMID:18022370, GO:0006680=PMID:19279011, GO:0050728=PMID:19279008, GO:0043407=PMID:19279008, GO:0071356=PMID:19279008, GO:0046513=PMID:19279011, GO:0023021=PMID:19279008, GO:0046512=PMID:19279011, GO:0043202=PMID:18022370} P04062 Glucosylceramidase protein 20110628 {GO:0006665=TAS, GO:0008219=IEA, GO:0006687=TAS, GO:0005975=IEA, GO:0032715=IDA, GO:0035307=IMP, GO:0005102=ISS, GO:0004348=IDA, GO:0044281=TAS, GO:0005765=ISS, GO:0006680=IMP, GO:0050728=IC, GO:0043407=IMP, GO:0071356=IMP, GO:0046513=IMP, GO:0023021=IMP, GO:0046512=IMP, GO:0043202=ISS} carbohydrate metabolic process, cell death, cellular response to tumor necrosis factor, ceramide biosynthetic process, glucosylceramide catabolic process, glycosphingolipid metabolic process, negative regulation of MAP kinase activity, negative regulation of inflammatory response, negative regulation of interleukin-6 production, positive regulation of protein dephosphorylation, small molecule metabolic process, sphingolipid metabolic process, sphingosine biosynthetic process, termination of signal transduction lysosomal lumen, lysosomal membrane glucosylceramidase activity, receptor binding Human UniProtKB:P17439 GBA2 Reactome UniProtKB {GO:0006665=Reactome:REACT_19323, GO:0006687=Reactome:REACT_116105, GO:0005886=Reactome:REACT_115724, GO:0008206=PMID:17105727, GO:0016139=PMID:11489889, GO:0004348=GO_REF:0000003, GO:0044281=Reactome:REACT_111217, GO:0016021=PMID:17105727, GO:0008422=PMID:11489889, GO:0005790=PMID:11489889, GO:0006680=GO_REF:0000002} Q9HCG7 Non-lysosomal glucosylceramidase protein 20130301 {GO:0006665=TAS, GO:0006687=TAS, GO:0005886=TAS, GO:0008206=IDA, GO:0016139=NAS, GO:0004348=IEA, GO:0044281=TAS, GO:0016021=IDA, GO:0008422=IDA, GO:0005790=TAS, GO:0006680=IEA} bile acid metabolic process, glucosylceramide catabolic process, glycoside catabolic process, glycosphingolipid metabolic process, small molecule metabolic process, sphingolipid metabolic process integral to membrane, plasma membrane, smooth endoplasmic reticulum beta-glucosidase activity, glucosylceramidase activity Human GBA3 Reactome UniProtKB {GO:0006665=Reactome:REACT_19323, GO:0017042=PMID:17595169, GO:0004565=PMID:17595169, GO:0006687=Reactome:REACT_116105, GO:0046477=PMID:17595169, GO:0005975=GO_REF:0000002, GO:0016139=PMID:11389701, GO:0044281=Reactome:REACT_111217, GO:0008422=PMID:17595169, GO:0005829=Reactome:REACT_115663} Q9H227 Cytosolic beta-glucosidase protein 20130301 {GO:0006665=TAS, GO:0017042=IDA, GO:0004565=IDA, GO:0006687=TAS, GO:0046477=IMP, GO:0005975=IEA, GO:0016139=IDA, GO:0044281=TAS, GO:0008422=IDA, GO:0005829=TAS} carbohydrate metabolic process, glycoside catabolic process, glycosphingolipid metabolic process, glycosylceramide catabolic process, small molecule metabolic process, sphingolipid metabolic process cytosol beta-galactosidase activity, beta-glucosidase activity, glycosylceramidase activity Human GBAS BHF-UCL UniProtKB {GO:0005515=PMID:20562859, GO:0005739=GO_REF:0000054, GO:0006754=PMID:20888800, GO:2000984=PMID:20888800, GO:0016020=PMID:9615231, GO:0005887=PMID:9615231, GO:0006119=PMID:20888800} O75323 Protein NipSnap homolog 2 protein 20120716 {GO:0005515=IPI, GO:0005739=IDA, GO:0006754=IMP, GO:2000984=IMP, GO:0016020=TAS, GO:0005887=TAS, GO:0006119=IMP} ATP biosynthetic process, negative regulation of ATP citrate synthase activity, oxidative phosphorylation integral to plasma membrane, membrane, mitochondrion protein binding Human GBE1 Reactome UniProtKB {GO:0005975=Reactome:REACT_474, GO:0043169=GO_REF:0000002, GO:0005978=Reactome:REACT_1736, GO:0005977=PMID:8613547, GO:0006006=Reactome:REACT_723, GO:0044281=Reactome:REACT_111217, GO:0006091=PMID:8613547, GO:0004553=GO_REF:0000002, GO:0003844=GO_REF:0000003, GO:0005829=Reactome:REACT_1560} Q04446 1,4-alpha-glucan-branching enzyme protein 20130301 {GO:0005975=TAS, GO:0043169=IEA, GO:0005978=TAS, GO:0005977=TAS, GO:0006006=TAS, GO:0044281=TAS, GO:0006091=TAS, GO:0004553=IEA, GO:0003844=IEA, GO:0005829=TAS} carbohydrate metabolic process, generation of precursor metabolites and energy, glucose metabolic process, glycogen biosynthetic process, glycogen metabolic process, small molecule metabolic process cytosol 1,4-alpha-glucan branching enzyme activity, cation binding, hydrolase activity, hydrolyzing O-glycosyl compounds Human GBF1 HPA UniProtKB {GO:0005802=GO_REF:0000033, GO:0005801=GO_REF:0000019, GO:0005794=GO_REF:0000052, GO:0005795=GO_REF:0000019, GO:0006890=Reactome:REACT_11208, GO:0006892=Reactome:REACT_11235, GO:0048205=Reactome:REACT_11096, GO:0005739=GO_REF:0000019, GO:0005086=GO_REF:0000033, GO:0000139=Reactome:REACT_14808, GO:0032012=GO_REF:0000002, GO:0005788=GO_REF:0000019, GO:0016192=GO_REF:0000033, GO:0016044=Reactome:REACT_11123, GO:0005777=GO_REF:0000019} Q92538 Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1 protein 20111111 {GO:0005802=IBA, GO:0005801=IEA, GO:0005794=IDA, GO:0005795=IEA, GO:0006890=TAS, GO:0006892=TAS, GO:0048205=TAS, GO:0005739=IEA, GO:0005086=IBA, GO:0000139=TAS, GO:0032012=IEA, GO:0005788=IEA, GO:0016192=IBA, GO:0016044=TAS, GO:0005777=IEA} COPI coating of Golgi vesicle, cellular membrane organization, post-Golgi vesicle-mediated transport, regulation of ARF protein signal transduction, retrograde vesicle-mediated transport, Golgi to ER, vesicle-mediated transport Golgi apparatus, Golgi membrane, Golgi stack, cis-Golgi network, endoplasmic reticulum lumen, mitochondrion, peroxisome, trans-Golgi network ARF guanyl-nucleotide exchange factor activity Human GBP1 Reactome UniProtKB {GO:0051607=GO_REF:0000037, GO:0000139=GO_REF:0000039, GO:0019221=Reactome:REACT_25229, GO:0003924=GO_REF:0000002, GO:0005576=GO_REF:0000039, GO:0005525=GO_REF:0000037, GO:0060333=Reactome:REACT_25078, GO:0005829=Reactome:REACT_25082} P32455 Interferon-induced guanylate-binding protein 1 protein 20130228 {GO:0051607=IEA, GO:0000139=IEA, GO:0019221=TAS, GO:0003924=IEA, GO:0005576=IEA, GO:0005525=IEA, GO:0060333=TAS, GO:0005829=TAS} cytokine-mediated signaling pathway, defense response to virus, interferon-gamma-mediated signaling pathway Golgi membrane, cytosol, extracellular region GTP binding, GTPase activity Human GBP2 Reactome UniProtKB {GO:0006955=PMID:1715024, GO:0060337=Reactome:REACT_25162, GO:0000139=GO_REF:0000039, GO:0019221=Reactome:REACT_25229, GO:0003924=GO_REF:0000002, GO:0005634=GO_REF:0000039, GO:0005525=GO_REF:0000037, GO:0060333=Reactome:REACT_25078, GO:0005829=Reactome:REACT_25192} P32456 Interferon-induced guanylate-binding protein 2 protein 20130228 {GO:0006955=TAS, GO:0060337=TAS, GO:0000139=IEA, GO:0019221=TAS, GO:0003924=IEA, GO:0005634=IEA, GO:0005525=IEA, GO:0060333=TAS, GO:0005829=TAS} cytokine-mediated signaling pathway, immune response, interferon-gamma-mediated signaling pathway, type I interferon-mediated signaling pathway Golgi membrane, cytosol, nucleus GTP binding, GTPase activity Human GBP3 UniProtKB UniProtKB {GO:0005737=GO_REF:0000039, GO:0051607=GO_REF:0000037, GO:0016020=GO_REF:0000039, GO:0003924=GO_REF:0000002, GO:0005525=GO_REF:0000037} Q9H0R5 Guanylate-binding protein 3 protein 20130413 {GO:0005737=IEA, GO:0051607=IEA, GO:0016020=IEA, GO:0003924=IEA, GO:0005525=IEA} defense response to virus cytoplasm, membrane GTP binding, GTPase activity Human UniProtKB-SubCell:SL-0162 GBP5 UniProtKB UniProtKB {GO:0016020=GO_REF:0000039, GO:0071346=GO_REF:0000019, GO:0003924=GO_REF:0000002, GO:0031410=GO_REF:0000019, GO:0005525=GO_REF:0000037} Q96PP8 Guanylate-binding protein 5 protein 20130413 {GO:0016020=IEA, GO:0071346=IEA, GO:0003924=IEA, GO:0031410=IEA, GO:0005525=IEA} cellular response to interferon-gamma cytoplasmic vesicle, membrane GTP binding, GTPase activity Human UniProtKB-SubCell:SL-0162 GBP7 UniProtKB UniProtKB {GO:0016020=GO_REF:0000039, GO:0003924=GO_REF:0000002, GO:0005525=GO_REF:0000037} Q8N8V2 Guanylate-binding protein 7 protein 20130413 {GO:0016020=IEA, GO:0003924=IEA, GO:0005525=IEA} membrane GTP binding, GTPase activity Human UniProtKB-SubCell:SL-0162 GC Reactome UniProtKB {GO:0051180=PMID:1696927, GO:0042359=Reactome:REACT_13523, GO:0051183=GO_REF:0000002, GO:0005576=Reactome:REACT_13727, GO:0003779=PMID:12119014, GO:0005499=GO_REF:0000037, GO:0044281=Reactome:REACT_111217, GO:0005615=GO_REF:0000002, GO:0008202=Reactome:REACT_11057, GO:0043202=Reactome:REACT_13664, GO:0005829=Reactome:REACT_13608} P02774 Vitamin D-binding protein protein 20100417 {GO:0051180=TAS, GO:0042359=TAS, GO:0051183=IEA, GO:0005576=TAS, GO:0003779=IPI, GO:0005499=IEA, GO:0044281=TAS, GO:0005615=IEA, GO:0008202=TAS, GO:0043202=TAS, GO:0005829=TAS} small molecule metabolic process, steroid metabolic process, vitamin D metabolic process, vitamin transport cytosol, extracellular region, extracellular space, lysosomal lumen actin binding, vitamin D binding, vitamin transporter activity Human GCA HPA UniProtKB {GO:0005737=GO_REF:0000052, GO:0006944=PMID:1530588, GO:0005886=GO_REF:0000052, GO:0005509=PMID:11717497, GO:0042803=PMID:11717497} P28676 Grancalcin protein 20101115 {GO:0005737=IDA, GO:0006944=TAS, GO:0005886=IDA, GO:0005509=IDA, GO:0042803=IPI} cellular membrane fusion cytoplasm, plasma membrane calcium ion binding, protein homodimerization activity Human GCAT UniProtKB UniProtKB {GO:0005739=GO_REF:0000029, GO:0006520=PMID:10712613, GO:0019518=GO_REF:0000041, GO:0009058=GO_REF:0000002, GO:0008890=PMID:10712613, GO:0030170=GO_REF:0000002, GO:0005634=GO_REF:0000039, GO:0003824=GO_REF:0000002} O75600 2-amino-3-ketobutyrate coenzyme A ligase, mitochondrial protein 20021104 {GO:0005739=NAS, GO:0006520=NAS, GO:0019518=IEA, GO:0009058=IEA, GO:0008890=NAS, GO:0030170=IEA, GO:0005634=IEA, GO:0003824=IEA} L-threonine catabolic process to glycine, biosynthetic process, cellular amino acid metabolic process mitochondrion, nucleus catalytic activity, glycine C-acetyltransferase activity, pyridoxal phosphate binding Human GCC1 HPA UniProtKB {GO:0005515=PMID:16189514, GO:0005737=GO_REF:0000052, GO:0005794=GO_REF:0000052, GO:0005886=GO_REF:0000052, GO:0000139=GO_REF:0000039, GO:0000042=GO_REF:0000002} Q96CN9 GRIP and coiled-coil domain-containing protein 1 protein 20101115 {GO:0005515=IPI, GO:0005737=IDA, GO:0005794=IDA, GO:0005886=IDA, GO:0000139=IEA, GO:0000042=IEA} protein targeting to Golgi Golgi apparatus, Golgi membrane, cytoplasm, plasma membrane protein binding Human GCC2 HPA UniProtKB {GO:0005515=PMID:18243103, GO:0005802=PMID:16885419, GO:0005794=GO_REF:0000052, GO:0034453=PMID:17543864, GO:0043001=PMID:16885419, GO:0090161=PMID:16885419, GO:0005634=GO_REF:0000052, GO:0071955=PMID:17488291, GO:0042802=PMID:18243103, GO:0070861=PMID:17488291, GO:0005737=GO_REF:0000052, GO:0016020=GO_REF:0000037, GO:0034499=PMID:16885419, GO:0031023=PMID:17543864, GO:0034067=PMID:16885419, GO:0006622=PMID:16885419, GO:0042147=PMID:17488291, GO:0000042=GO_REF:0000002} Q8IWJ2 GRIP and coiled-coil domain-containing protein 2 protein 20110516 {GO:0005515=IPI, GO:0005802=IDA, GO:0005794=IDA, GO:0034453=IMP, GO:0043001=IMP, GO:0090161=IMP, GO:0005634=IDA, GO:0071955=IMP, GO:0042802=IPI, GO:0070861=IMP, GO:0005737=IDA, GO:0016020=IEA, GO:0034499=IMP, GO:0031023=IMP, GO:0034067=IMP, GO:0006622=IMP, GO:0042147=IMP, GO:0000042=IEA} Golgi ribbon formation, Golgi to plasma membrane protein transport, late endosome to Golgi transport, microtubule anchoring, microtubule organizing center organization, protein localization to Golgi apparatus, protein targeting to Golgi, protein targeting to lysosome, recycling endosome to Golgi transport, regulation of protein exit from endoplasmic reticulum, retrograde transport, endosome to Golgi Golgi apparatus, cytoplasm, membrane, nucleus, trans-Golgi network identical protein binding, protein binding Human GCDH Reactome UniProtKB {GO:0019395=GO_REF:0000019, GO:0050660=GO_REF:0000019, GO:0005743=GO_REF:0000019, GO:0044281=Reactome:REACT_111217, GO:0004361=Reactome:REACT_1409, GO:0005739=PMID:8541831, GO:0034641=Reactome:REACT_13, GO:0005759=Reactome:REACT_1409, GO:0003995=GO_REF:0000002, GO:0046949=GO_REF:0000019, GO:0006554=Reactome:REACT_1298, GO:0000062=GO_REF:0000019, GO:0006568=GO_REF:0000041} Q92947 Glutaryl-CoA dehydrogenase, mitochondrial protein 20100212 {GO:0019395=IEA, GO:0050660=IEA, GO:0005743=IEA, GO:0044281=TAS, GO:0004361=EXP, GO:0005739=TAS, GO:0034641=TAS, GO:0005759=TAS, GO:0003995=IEA, GO:0046949=IEA, GO:0006554=TAS, GO:0000062=IEA, GO:0006568=IEA} cellular nitrogen compound metabolic process, fatty acid oxidation, fatty-acyl-CoA biosynthetic process, lysine catabolic process, small molecule metabolic process, tryptophan metabolic process mitochondrial inner membrane, mitochondrial matrix, mitochondrion acyl-CoA dehydrogenase activity, fatty-acyl-CoA binding, flavin adenine dinucleotide binding, glutaryl-CoA dehydrogenase activity Human GCFC2 UniProtKB UniProtKB {GO:0006355=PMID:10500253, GO:0003700=GO_REF:0000002, GO:0005634=GO_REF:0000039, GO:0045892=PMID:10500253, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} P16383 GC-rich sequence DNA-binding factor 2 protein 20091215 {GO:0006355=NAS, GO:0003700=IEA, GO:0005634=IEA, GO:0045892=NAS, GO:0003677=IEA, GO:0006351=IEA} negative regulation of transcription, DNA-dependent, regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus DNA binding, sequence-specific DNA binding transcription factor activity Human GCG Reactome UniProtKB {GO:0007631=PMID:8538742, GO:0005886=Reactome:REACT_22268, GO:0008283=PMID:10861272, GO:0030819=GO_REF:0000019, GO:0010737=GO_REF:0000019, GO:0044281=Reactome:REACT_111217, GO:0090280=GO_REF:0000019, GO:0005615=GO_REF:0000019, GO:0032092=GO_REF:0000019, GO:0033138=GO_REF:0000019, GO:0071377=Reactome:REACT_1665, GO:0045860=GO_REF:0000019, GO:0070374=GO_REF:0000019, GO:0010800=GO_REF:0000019, GO:0043066=GO_REF:0000019, GO:0035774=GO_REF:0000019, GO:0005102=PMID:9990065, GO:0005576=Reactome:REACT_24006, GO:0007165=PMID:7929237, GO:0006112=Reactome:REACT_1505, GO:0005179=GO_REF:0000037, GO:0007186=PMID:9990065, GO:0050796=Reactome:REACT_23974, GO:0005788=Reactome:REACT_24009, GO:0044267=Reactome:REACT_17015, GO:0034774=Reactome:REACT_24006} P01275 Glucagon protein 20090220 {GO:0007631=TAS, GO:0005886=TAS, GO:0008283=TAS, GO:0030819=IEA, GO:0010737=IEA, GO:0044281=TAS, GO:0090280=IEA, GO:0005615=IEA, GO:0032092=IEA, GO:0033138=IEA, GO:0071377=TAS, GO:0045860=IEA, GO:0070374=IEA, GO:0010800=IEA, GO:0043066=IEA, GO:0035774=IEA, GO:0005102=TAS, GO:0005576=TAS, GO:0007165=TAS, GO:0006112=TAS, GO:0005179=IEA, GO:0007186=TAS, GO:0050796=TAS, GO:0005788=TAS, GO:0044267=TAS, GO:0034774=TAS} G-protein coupled receptor signaling pathway, cell proliferation, cellular protein metabolic process, cellular response to glucagon stimulus, energy reserve metabolic process, feeding behavior, negative regulation of apoptotic process, positive regulation of ERK1 and ERK2 cascade, positive regulation of cAMP biosynthetic process, positive regulation of calcium ion import, positive regulation of insulin secretion involved in cellular response to glucose stimulus, positive regulation of peptidyl-serine phosphorylation, positive regulation of peptidyl-threonine phosphorylation, positive regulation of protein binding, positive regulation of protein kinase activity, protein kinase A signaling cascade, regulation of insulin secretion, signal transduction, small molecule metabolic process endoplasmic reticulum lumen, extracellular region, extracellular space, plasma membrane, secretory granule lumen hormone activity, receptor binding Human GCGR Reactome UniProtKB {GO:0005886=Reactome:REACT_22436, GO:0007584=PMID:7773293, GO:0044281=Reactome:REACT_111217, GO:0006091=PMID:7773293, GO:0006887=GO_REF:0000019, GO:0004967=GO_REF:0000019, GO:0005085=Reactome:REACT_22110, GO:0006112=Reactome:REACT_1505, GO:0009755=GO_REF:0000019, GO:0071377=Reactome:REACT_1665, GO:0008217=PMID:8563746, GO:0007188=PMID:8144028, GO:0007189=GO_REF:0000019, GO:0016021=GO_REF:0000037, GO:0017046=GO_REF:0000019, GO:0005768=GO_REF:0000019} P47871 Glucagon receptor protein 20090511 {GO:0005886=TAS, GO:0007584=TAS, GO:0044281=TAS, GO:0006091=TAS, GO:0006887=IEA, GO:0004967=IEA, GO:0005085=TAS, GO:0006112=TAS, GO:0009755=IEA, GO:0071377=TAS, GO:0008217=TAS, GO:0007188=TAS, GO:0007189=IEA, GO:0016021=IEA, GO:0017046=IEA, GO:0005768=IEA} adenylate cyclase-activating G-protein coupled receptor signaling pathway, adenylate cyclase-modulating G-protein coupled receptor signaling pathway, cellular response to glucagon stimulus, energy reserve metabolic process, exocytosis, generation of precursor metabolites and energy, hormone-mediated signaling pathway, regulation of blood pressure, response to nutrient, small molecule metabolic process endosome, integral to membrane, plasma membrane glucagon receptor activity, guanyl-nucleotide exchange factor activity, peptide hormone binding Human GCH1 HPA UniProtKB {GO:0005515=PMID:21988832, GO:0050662=GO_REF:0000019, GO:0014916=GO_REF:0000019, GO:0006729=PMID:9445252, GO:0050999=Reactome:REACT_12389, GO:0005634=GO_REF:0000052, GO:0044281=Reactome:REACT_111217, GO:0045776=GO_REF:0000019, GO:0051291=GO_REF:0000019, GO:0042803=PMID:1669853, GO:0005829=Reactome:REACT_111143, GO:0006809=PMID:9445252, GO:0042416=PMID:16338639, GO:0005737=GO_REF:0000052, GO:0042311=GO_REF:0000019, GO:0050884=PMID:7874165, GO:0032496=PMID:7678411, GO:0046654=GO_REF:0000002, GO:0046209=Reactome:REACT_12508, GO:0051260=PMID:11087823, GO:0034341=PMID:12607127, GO:0031965=GO_REF:0000052, GO:0005509=GO_REF:0000019, GO:0005730=GO_REF:0000052, GO:0003934=PMID:7874165, GO:0006917=GO_REF:0000019, GO:0031410=PMID:3318829, GO:0005525=PMID:14717702, GO:0042559=PMID:2463916, GO:0035998=GO_REF:0000041, GO:0006184=PMID:2463916, GO:0043234=PMID:11087823, GO:0030742=GO_REF:0000019, GO:0051000=PMID:12176133, GO:0008217=PMID:17717598, GO:0008270=PMID:11087823, GO:0048265=GO_REF:0000024, GO:0034612=PMID:9445252} P30793 GTP cyclohydrolase 1 protein 20101115 {GO:0005515=IPI, GO:0050662=IEA, GO:0014916=IEA, GO:0006729=IDA, GO:0050999=TAS, GO:0005634=IDA, GO:0044281=TAS, GO:0045776=IEA, GO:0051291=IEA, GO:0042803=IPI, GO:0005829=TAS, GO:0006809=NAS, GO:0042416=IDA, GO:0005737=IDA, GO:0042311=IEA, GO:0050884=IMP, GO:0032496=IDA, GO:0046654=IEA, GO:0046209=TAS, GO:0051260=IDA, GO:0034341=IDA, GO:0031965=IDA, GO:0005509=IEA, GO:0005730=IDA, GO:0003934=IDA, GO:0006917=IEA, GO:0031410=IDA, GO:0005525=IDA, GO:0042559=IDA, GO:0035998=IEA, GO:0006184=IDA, GO:0043234=IDA, GO:0030742=IEA, GO:0051000=IDA, GO:0008217=IMP, GO:0008270=IDA, GO:0048265=ISS, GO:0034612=IDA} 7,8-dihydroneopterin 3'-triphosphate biosynthetic process, GTP catabolic process, dopamine biosynthetic process, induction of apoptosis, negative regulation of blood pressure, neuromuscular process controlling posture, nitric oxide biosynthetic process, nitric oxide metabolic process, positive regulation of nitric-oxide synthase activity, protein heterooligomerization, protein homooligomerization, pteridine-containing compound biosynthetic process, regulation of blood pressure, regulation of lung blood pressure, regulation of nitric-oxide synthase activity, response to interferon-gamma, response to lipopolysaccharide, response to pain, response to tumor necrosis factor, small molecule metabolic process, tetrahydrobiopterin biosynthetic process, tetrahydrofolate biosynthetic process, vasodilation cytoplasm, cytoplasmic vesicle, cytosol, nuclear membrane, nucleolus, nucleus, protein complex GTP binding, GTP cyclohydrolase I activity, GTP-dependent protein binding, calcium ion binding, coenzyme binding, protein binding, protein homodimerization activity, zinc ion binding Human GCHFR Reactome UniProtKB {GO:0005515=PMID:9092499, GO:0004857=GO_REF:0000019, GO:0042470=PMID:16778797, GO:0031965=PMID:16778797, GO:0050999=Reactome:REACT_12389, GO:0005634=PMID:16778797, GO:0044281=Reactome:REACT_111217, GO:0051291=GO_REF:0000019, GO:0030425=PMID:16778797, GO:0005829=Reactome:REACT_111115, GO:0006809=PMID:8702680, GO:0009890=GO_REF:0000002, GO:0043234=GO_REF:0000019, GO:0005737=PMID:16778797, GO:0030742=GO_REF:0000019, GO:0016787=GO_REF:0000038, GO:0046209=Reactome:REACT_12508, GO:0043105=GO_REF:0000019, GO:0016597=GO_REF:0000019, GO:0042133=PMID:8702680, GO:0044549=GO_REF:0000019} P30047 GTP cyclohydrolase 1 feedback regulatory protein protein 20110804 {GO:0005515=IPI, GO:0004857=IEA, GO:0042470=IDA, GO:0031965=IDA, GO:0050999=TAS, GO:0005634=IDA, GO:0044281=TAS, GO:0051291=IEA, GO:0030425=IDA, GO:0005829=TAS, GO:0006809=TAS, GO:0009890=IEA, GO:0043234=IEA, GO:0005737=IDA, GO:0030742=IEA, GO:0016787=IEA, GO:0046209=TAS, GO:0043105=IEA, GO:0016597=IEA, GO:0042133=TAS, GO:0044549=IEA} negative regulation of GTP cyclohydrolase I activity, negative regulation of biosynthetic process, neurotransmitter metabolic process, nitric oxide biosynthetic process, nitric oxide metabolic process, protein heterooligomerization, regulation of nitric-oxide synthase activity, small molecule metabolic process cytoplasm, cytosol, dendrite, melanosome, nuclear membrane, nucleus, protein complex GTP cyclohydrolase binding, GTP-dependent protein binding, amino acid binding, enzyme inhibitor activity, hydrolase activity, protein binding Human GCK BHF-UCL UniProtKB {GO:0005515=PMID:11522786, GO:0032811=GO_REF:0000019, GO:0001678=GO_REF:0000033, GO:0044281=Reactome:REACT_111217, GO:0004396=GO_REF:0000002, GO:0043266=GO_REF:0000019, GO:0007204=GO_REF:0000019, GO:0005536=PMID:12941786, GO:0006096=GO_REF:0000019, GO:0008645=Reactome:REACT_9441, GO:0005829=Reactome:REACT_6938, GO:0005739=GO_REF:0000019, GO:0008865=GO_REF:0000033, GO:0015758=Reactome:REACT_212, GO:0016301=GO_REF:0000038, GO:0044320=GO_REF:0000024, GO:0016773=GO_REF:0000002, GO:0032024=PMID:8878425, GO:0042149=GO_REF:0000019, GO:0006003=GO_REF:0000019, GO:0030141=GO_REF:0000019, GO:0045821=GO_REF:0000019, GO:0019158=GO_REF:0000033, GO:0045721=PMID:8878425, GO:0032869=GO_REF:0000024, GO:0000287=GO_REF:0000019, GO:0045725=PMID:8878425, GO:0005975=Reactome:REACT_474, GO:0019903=GO_REF:0000019, GO:0005978=GO_REF:0000019, GO:0006739=GO_REF:0000019, GO:0042593=PMID:20668700, GO:0055085=Reactome:REACT_19118, GO:0005524=PMID:12941786, GO:0010827=Reactome:REACT_6804, GO:0006110=PMID:9570959, GO:0004340=PMID:12941786, GO:0070509=GO_REF:0000019, GO:0051594=PMID:12941786, GO:0050796=PMID:20668700, GO:0043531=GO_REF:0000019, GO:0044448=GO_REF:0000019, GO:0031018=Reactome:REACT_13819, GO:0019932=GO_REF:0000019, GO:0005654=Reactome:REACT_6938, GO:0042327=GO_REF:0000019} P35557 Glucokinase protein 20100929 {GO:0005515=IPI, GO:0032811=IEA, GO:0001678=IBA, GO:0044281=TAS, GO:0004396=IEA, GO:0043266=IEA, GO:0007204=IEA, GO:0005536=IDA, GO:0006096=IEA, GO:0008645=TAS, GO:0005829=TAS, GO:0005739=IEA, GO:0008865=IBA, GO:0015758=TAS, GO:0016301=IEA, GO:0044320=ISS, GO:0016773=IEA, GO:0032024=IMP, GO:0042149=IEA, GO:0006003=IEA, GO:0030141=IEA, GO:0045821=IEA, GO:0019158=IBA, GO:0045721=IMP, GO:0032869=ISS, GO:0000287=IEA, GO:0045725=IMP, GO:0005975=TAS, GO:0019903=IEA, GO:0005978=IEA, GO:0006739=IEA, GO:0042593=IMP, GO:0055085=TAS, GO:0005524=IDA, GO:0010827=TAS, GO:0006110=NAS, GO:0004340=IDA, GO:0070509=IEA, GO:0051594=IMP, GO:0050796=IMP, GO:0043531=IEA, GO:0044448=IEA, GO:0031018=TAS, GO:0019932=IEA, GO:0005654=TAS, GO:0042327=IEA} NADP metabolic process, calcium ion import, carbohydrate metabolic process, cellular glucose homeostasis, cellular response to glucose starvation, cellular response to insulin stimulus, cellular response to leptin stimulus, detection of glucose, elevation of cytosolic calcium ion concentration, endocrine pancreas development, fructose 2,6-bisphosphate metabolic process, glucose homeostasis, glucose transport, glycogen biosynthetic process, glycolysis, hexose transport, negative regulation of epinephrine secretion, negative regulation of gluconeogenesis, positive regulation of glycogen biosynthetic process, positive regulation of glycolysis, positive regulation of insulin secretion, positive regulation of phosphorylation, regulation of glucose transport, regulation of glycolysis, regulation of insulin secretion, regulation of potassium ion transport, second-messenger-mediated signaling, small molecule metabolic process, transmembrane transport cell cortex part, cytosol, mitochondrion, nucleoplasm, secretory granule ADP binding, ATP binding, fructokinase activity, glucokinase activity, glucose binding, hexokinase activity, kinase activity, magnesium ion binding, mannokinase activity, phosphotransferase activity, alcohol group as acceptor, protein binding, protein phosphatase binding Human UniProtKB:P17712 GCKR BHF-UCL UniProtKB {GO:0005515=PMID:11522786, GO:0004857=GO_REF:0000019, GO:0001678=GO_REF:0000019, GO:0005975=Reactome:REACT_474, GO:0070095=PMID:14627435, GO:0019904=GO_REF:0000019, GO:0070328=PMID:19526250, GO:0033133=GO_REF:0000019, GO:0005634=GO_REF:0000019, GO:0044281=Reactome:REACT_111217, GO:0033132=PMID:14627435, GO:0046415=PMID:19503597, GO:0055085=Reactome:REACT_19118, GO:0010827=Reactome:REACT_6804, GO:0008645=Reactome:REACT_9441, GO:0005829=Reactome:REACT_6938, GO:0005739=GO_REF:0000019, GO:0015758=Reactome:REACT_212, GO:0016301=GO_REF:0000038, GO:0009750=PMID:14627435, GO:0030246=GO_REF:0000019, GO:0005654=Reactome:REACT_6938, GO:0019899=GO_REF:0000019, GO:0000060=GO_REF:0000024} Q14397 Glucokinase regulatory protein protein 20100929 {GO:0005515=IPI, GO:0004857=IEA, GO:0001678=IEA, GO:0005975=TAS, GO:0070095=IDA, GO:0019904=IEA, GO:0070328=IMP, GO:0033133=IEA, GO:0005634=IEA, GO:0044281=TAS, GO:0033132=IDA, GO:0046415=IMP, GO:0055085=TAS, GO:0010827=TAS, GO:0008645=TAS, GO:0005829=TAS, GO:0005739=IEA, GO:0015758=TAS, GO:0016301=IEA, GO:0009750=IDA, GO:0030246=IEA, GO:0005654=TAS, GO:0019899=IEA, GO:0000060=ISS} carbohydrate metabolic process, cellular glucose homeostasis, glucose transport, hexose transport, negative regulation of glucokinase activity, positive regulation of glucokinase activity, protein import into nucleus, translocation, regulation of glucose transport, response to fructose stimulus, small molecule metabolic process, transmembrane transport, triglyceride homeostasis, urate metabolic process cytosol, mitochondrion, nucleoplasm, nucleus carbohydrate binding, enzyme binding, enzyme inhibitor activity, fructose-6-phosphate binding, kinase activity, protein binding, protein domain specific binding Human GCLC Reactome UniProtKB {GO:0050662=PMID:9841880, GO:0046685=GO_REF:0000019, GO:0006805=Reactome:REACT_13433, GO:0009408=PMID:8104187, GO:0006534=PMID:2294991, GO:0032436=GO_REF:0000019, GO:0044281=Reactome:REACT_111217, GO:0051409=GO_REF:0000019, GO:0005829=Reactome:REACT_6970, GO:0034641=Reactome:REACT_13, GO:0043524=GO_REF:0000019, GO:0005737=GO_REF:0000033, GO:0050880=PMID:12598062, GO:0051900=GO_REF:0000019, GO:0004357=PMID:16183645, GO:0006750=Reactome:REACT_6960, GO:0031397=GO_REF:0000019, GO:0009725=PMID:8104187, GO:0009410=GO_REF:0000019, GO:0006979=PMID:10395918, GO:0043066=PMID:10439045, GO:0000287=PMID:24639, GO:0046982=GO_REF:0000019, GO:0006536=PMID:12663448, GO:0005524=GO_REF:0000037, GO:0019852=GO_REF:0000019, GO:0000096=Reactome:REACT_115639, GO:0043531=PMID:24639, GO:0017109=GO_REF:0000019, GO:0045454=PMID:10439045, GO:0016595=PMID:9841880, GO:0045892=PMID:10439045} P48506 Glutamate--cysteine ligase catalytic subunit protein 20130213 {GO:0050662=IPI, GO:0046685=IEA, GO:0006805=TAS, GO:0009408=IDA, GO:0006534=IDA, GO:0032436=IEA, GO:0044281=TAS, GO:0051409=IEA, GO:0005829=TAS, GO:0034641=TAS, GO:0043524=IEA, GO:0005737=IBA, GO:0050880=IMP, GO:0051900=IEA, GO:0004357=IMP, GO:0006750=TAS, GO:0031397=IEA, GO:0009725=IDA, GO:0009410=IEA, GO:0006979=IDA, GO:0043066=IDA, GO:0000287=IDA, GO:0046982=IEA, GO:0006536=IDA, GO:0005524=IEA, GO:0019852=IEA, GO:0000096=TAS, GO:0043531=IDA, GO:0017109=IEA, GO:0045454=IDA, GO:0016595=IDA, GO:0045892=IDA} L-ascorbic acid metabolic process, cell redox homeostasis, cellular nitrogen compound metabolic process, cysteine metabolic process, glutamate metabolic process, glutathione biosynthetic process, negative regulation of apoptotic process, negative regulation of neuron apoptotic process, negative regulation of protein ubiquitination, negative regulation of transcription, DNA-dependent, positive regulation of proteasomal ubiquitin-dependent protein catabolic process, regulation of blood vessel size, regulation of mitochondrial depolarization, response to arsenic-containing substance, response to heat, response to hormone stimulus, response to nitrosative stress, response to oxidative stress, response to xenobiotic stimulus, small molecule metabolic process, sulfur amino acid metabolic process, xenobiotic metabolic process cytoplasm, cytosol, glutamate-cysteine ligase complex ADP binding, ATP binding, coenzyme binding, glutamate binding, glutamate-cysteine ligase activity, magnesium ion binding, protein heterodimerization activity Human GCLM Reactome UniProtKB {GO:0006805=Reactome:REACT_13433, GO:0046982=GO_REF:0000019, GO:0006536=PMID:9841880, GO:0006534=GO_REF:0000019, GO:0042493=PMID:9895302, GO:0044281=Reactome:REACT_111217, GO:0051409=GO_REF:0000019, GO:0005829=Reactome:REACT_6970, GO:0034641=Reactome:REACT_13, GO:0043524=GO_REF:0000019, GO:0035226=PMID:9841880, GO:0050880=PMID:12975258, GO:0051900=GO_REF:0000019, GO:0000096=Reactome:REACT_115639, GO:0035229=GO_REF:0000019, GO:0004357=PMID:16183645, GO:0006750=Reactome:REACT_6960, GO:0017109=GO_REF:0000019, GO:0006979=PMID:10395918} P48507 Glutamate--cysteine ligase regulatory subunit protein 20130213 {GO:0006805=TAS, GO:0046982=IEA, GO:0006536=IDA, GO:0006534=IEA, GO:0042493=IDA, GO:0044281=TAS, GO:0051409=IEA, GO:0005829=TAS, GO:0034641=TAS, GO:0043524=IEA, GO:0035226=IPI, GO:0050880=IMP, GO:0051900=IEA, GO:0000096=TAS, GO:0035229=IEA, GO:0004357=IMP, GO:0006750=TAS, GO:0017109=IEA, GO:0006979=IDA} cellular nitrogen compound metabolic process, cysteine metabolic process, glutamate metabolic process, glutathione biosynthetic process, negative regulation of neuron apoptotic process, positive regulation of glutamate-cysteine ligase activity, regulation of blood vessel size, regulation of mitochondrial depolarization, response to drug, response to nitrosative stress, response to oxidative stress, small molecule metabolic process, sulfur amino acid metabolic process, xenobiotic metabolic process cytosol, glutamate-cysteine ligase complex glutamate-cysteine ligase activity, glutamate-cysteine ligase catalytic subunit binding, protein heterodimerization activity Human GCM1 PINC UniProtKB {GO:0005667=PMID:15385555, GO:0006355=PMID:15385555, GO:0003700=PMID:15385555, GO:0060018=GO_REF:0000019, GO:0060706=GO_REF:0000019, GO:0060670=GO_REF:0000019, GO:0005634=PMID:8962155, GO:0008270=GO_REF:0000019, GO:0009653=PMID:8962155, GO:0003677=GO_REF:0000019, GO:0006351=GO_REF:0000037, GO:0008134=PMID:15385555} Q9NP62 Chorion-specific transcription factor GCMa protein 20050308 {GO:0005667=IDA, GO:0006355=IDA, GO:0003700=IDA, GO:0060018=IEA, GO:0060706=IEA, GO:0060670=IEA, GO:0005634=TAS, GO:0008270=IEA, GO:0009653=TAS, GO:0003677=IEA, GO:0006351=IEA, GO:0008134=IPI} anatomical structure morphogenesis, astrocyte fate commitment, branching involved in labyrinthine layer morphogenesis, cell differentiation involved in embryonic placenta development, regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus, transcription factor complex DNA binding, sequence-specific DNA binding transcription factor activity, transcription factor binding, zinc ion binding Human GCN1L1 GOC UniProtKB {GO:0005737=GO_REF:0000052, GO:0005840=PMID:9234705, GO:0006412=PMID:9234705, GO:0008135=PMID:9234705, GO:0006417=GO_REF:0000037} Q92616 Translational activator GCN1 protein 20130413 {GO:0005737=IDA, GO:0005840=NAS, GO:0006412=NAS, GO:0008135=NAS, GO:0006417=IEA} regulation of translation, translation cytoplasm, ribosome translation factor activity, nucleic acid binding Human GCNT1 Reactome UniProtKB {GO:0032868=GO_REF:0000019, GO:0003829=GO_REF:0000003, GO:0000139=Reactome:REACT_115905, GO:0006493=PMID:1329093, GO:0060993=GO_REF:0000019, GO:0048729=GO_REF:0000019, GO:0016266=Reactome:REACT_115606, GO:0016021=GO_REF:0000037, GO:0044267=Reactome:REACT_17015, GO:0005615=GO_REF:0000019, GO:0043687=Reactome:REACT_22161} Q02742 Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase protein 20130301 {GO:0032868=IEA, GO:0003829=IEA, GO:0000139=TAS, GO:0006493=TAS, GO:0060993=IEA, GO:0048729=IEA, GO:0016266=TAS, GO:0016021=IEA, GO:0044267=TAS, GO:0005615=IEA, GO:0043687=TAS} O-glycan processing, cellular protein metabolic process, kidney morphogenesis, post-translational protein modification, protein O-linked glycosylation, response to insulin stimulus, tissue morphogenesis Golgi membrane, extracellular space, integral to membrane beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity Human GCNT3 Reactome UniProtKB {GO:0003829=GO_REF:0000003, GO:0005975=PMID:9988682, GO:0002426=GO_REF:0000019, GO:0016266=Reactome:REACT_115606, GO:0008109=GO_REF:0000003, GO:0050892=GO_REF:0000019, GO:0016020=PMID:9988682, GO:0006493=PMID:9988682, GO:0000139=Reactome:REACT_115905, GO:0060993=GO_REF:0000019, GO:0048729=GO_REF:0000019, GO:0016021=GO_REF:0000037, GO:0044267=Reactome:REACT_17015, GO:0047225=GO_REF:0000019, GO:0043687=Reactome:REACT_22161} O95395 Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase 3 protein 20130301 {GO:0003829=IEA, GO:0005975=NAS, GO:0002426=IEA, GO:0016266=TAS, GO:0008109=IEA, GO:0050892=IEA, GO:0016020=TAS, GO:0006493=TAS, GO:0000139=TAS, GO:0060993=IEA, GO:0048729=IEA, GO:0016021=IEA, GO:0044267=TAS, GO:0047225=IEA, GO:0043687=TAS} O-glycan processing, carbohydrate metabolic process, cellular protein metabolic process, immunoglobulin production in mucosal tissue, intestinal absorption, kidney morphogenesis, post-translational protein modification, protein O-linked glycosylation, tissue morphogenesis Golgi membrane, integral to membrane, membrane N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity, acetylgalactosaminyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity, beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity Human GCSH PINC UniProtKB {GO:0005739=GO_REF:0000039, GO:0005960=GO_REF:0000002, GO:0019464=GO_REF:0000019, GO:0004047=GO_REF:0000019, GO:0006546=PMID:1671321, GO:0019899=GO_REF:0000019} P23434 Glycine cleavage system H protein, mitochondrial protein 20030904 {GO:0005739=IEA, GO:0005960=IEA, GO:0019464=IEA, GO:0004047=IEA, GO:0006546=TAS, GO:0019899=IEA} glycine catabolic process, glycine decarboxylation via glycine cleavage system glycine cleavage complex, mitochondrion aminomethyltransferase activity, enzyme binding Human GDA Reactome UniProtKB {GO:0005622=PMID:10542258, GO:0006147=GO_REF:0000041, GO:0006195=Reactome:REACT_2086, GO:0006139=PMID:10075721, GO:0006144=Reactome:REACT_522, GO:0008892=Reactome:REACT_1442, GO:0055086=Reactome:REACT_1698, GO:0008270=GO_REF:0000002, GO:0044281=Reactome:REACT_111217, GO:0005829=Reactome:REACT_1442, GO:0007399=PMID:10542258} Q9Y2T3 Guanine deaminase protein 20130213 {GO:0005622=TAS, GO:0006147=IEA, GO:0006195=TAS, GO:0006139=TAS, GO:0006144=TAS, GO:0008892=EXP, GO:0055086=TAS, GO:0008270=IEA, GO:0044281=TAS, GO:0005829=TAS, GO:0007399=TAS} guanine catabolic process, nervous system development, nucleobase-containing compound metabolic process, nucleobase-containing small molecule metabolic process, purine nucleobase metabolic process, purine nucleotide catabolic process, small molecule metabolic process cytosol, intracellular guanine deaminase activity, zinc ion binding Human GDAP1 UniProtKB UniProtKB {GO:0000266=PMID:15772096, GO:0006626=PMID:15772096, GO:0031307=PMID:15772096, GO:0032526=GO_REF:0000019} Q8TB36 Ganglioside-induced differentiation-associated protein 1 protein 20120608 {GO:0000266=IDA, GO:0006626=IMP, GO:0031307=IDA, GO:0032526=IEA} mitochondrial fission, protein targeting to mitochondrion, response to retinoic acid integral to mitochondrial outer membrane Human GDAP1L1 null null {} null null null null {} null null null GDAP2 ENSEMBL UniProtKB {GO:0032526=GO_REF:0000019} Q9NXN4 Ganglioside-induced differentiation-associated protein 2 protein 20130413 {GO:0032526=IEA} response to retinoic acid Human Ensembl:ENSMUSP00000029459 GDE1 UniProtKB UniProtKB {GO:0006629=PMID:10760272, GO:0005737=GO_REF:0000039, GO:0008081=GO_REF:0000002, GO:0047395=GO_REF:0000003, GO:0016021=PMID:10760272, GO:0008889=PMID:10760272, GO:0006071=GO_REF:0000002, GO:0046872=GO_REF:0000037} Q9NZC3 Glycerophosphodiester phosphodiesterase 1 protein 20010824 {GO:0006629=TAS, GO:0005737=IEA, GO:0008081=IEA, GO:0047395=IEA, GO:0016021=TAS, GO:0008889=TAS, GO:0006071=IEA, GO:0046872=IEA} glycerol metabolic process, lipid metabolic process cytoplasm, integral to membrane glycerophosphodiester phosphodiesterase activity, glycerophosphoinositol glycerophosphodiesterase activity, metal ion binding, phosphoric diester hydrolase activity Human GDF10 UniProtKB UniProtKB {GO:0001501=PMID:8670277, GO:0005576=GO_REF:0000038, GO:0007179=PMID:8679252, GO:0008083=GO_REF:0000038, GO:0005615=GO_REF:0000037, GO:0005125=GO_REF:0000037, GO:0040007=GO_REF:0000002} Q8N6T2 GDF10 protein protein 20130413 {GO:0001501=TAS, GO:0005576=IEA, GO:0007179=TAS, GO:0008083=IEA, GO:0005615=IEA, GO:0005125=IEA, GO:0040007=IEA} growth, skeletal system development, transforming growth factor beta receptor signaling pathway extracellular region, extracellular space cytokine activity, growth factor activity Human UniProtKB-KW:KW-0339 GDF11 UniProtKB UniProtKB {GO:0001656=GO_REF:0000019, GO:0001657=GO_REF:0000019, GO:0021512=GO_REF:0000019, GO:0008285=GO_REF:0000019, GO:0005576=GO_REF:0000038, GO:0005575=GO_REF:0000015, GO:0048593=GO_REF:0000019, GO:0005615=GO_REF:0000019, GO:0005125=GO_REF:0000029, GO:0007399=PMID:10075854, GO:0001501=PMID:10391213, GO:0031016=GO_REF:0000019, GO:0007498=PMID:10075854, GO:0048469=GO_REF:0000019, GO:0045596=GO_REF:0000019, GO:0040007=GO_REF:0000002, GO:0008083=GO_REF:0000037} O95390 Growth/differentiation factor 11 protein 20061026 {GO:0001656=IEA, GO:0001657=IEA, GO:0021512=IEA, GO:0008285=IEA, GO:0005576=IEA, GO:0005575=ND, GO:0048593=IEA, GO:0005615=IEA, GO:0005125=NAS, GO:0007399=TAS, GO:0001501=TAS, GO:0031016=IEA, GO:0007498=TAS, GO:0048469=IEA, GO:0045596=IEA, GO:0040007=IEA, GO:0008083=IEA} camera-type eye morphogenesis, cell maturation, growth, mesoderm development, metanephros development, negative regulation of cell differentiation, negative regulation of cell proliferation, nervous system development, pancreas development, skeletal system development, spinal cord anterior/posterior patterning, ureteric bud development cellular_component, extracellular region, extracellular space cytokine activity, growth factor activity Human GDF15 PINC UniProtKB {GO:0007165=PMID:9326641, GO:0007267=PMID:9326641, GO:0007179=PMID:9348093, GO:0005576=PMID:9326641, GO:0008083=GO_REF:0000037, GO:0005615=GO_REF:0000037, GO:0005125=GO_REF:0000037} Q99988 Growth/differentiation factor 15 protein 20030904 {GO:0007165=TAS, GO:0007267=TAS, GO:0007179=TAS, GO:0005576=TAS, GO:0008083=IEA, GO:0005615=IEA, GO:0005125=IEA} cell-cell signaling, signal transduction, transforming growth factor beta receptor signaling pathway extracellular region, extracellular space cytokine activity, growth factor activity Human GDF2 BHF-UCL UniProtKB {GO:0005515=PMID:17068149, GO:0030308=PMID:17068149, GO:0051216=PMID:20406889, GO:0048514=PMID:20406889, GO:0005615=GO_REF:0000037, GO:0032757=PMID:19366699, GO:0006879=PMID:20406889, GO:0030513=GO_REF:0000019, GO:0001569=PMID:20406889, GO:0010862=PMID:17068149, GO:0030509=PMID:17068149, GO:0032924=PMID:17068149, GO:0005125=GO_REF:0000037, GO:0001649=GO_REF:0000019, GO:0045766=PMID:20406889, GO:0045669=GO_REF:0000019, GO:0010596=PMID:17068149, GO:0001503=PMID:20406889, GO:0001938=PMID:20406889, GO:0001937=PMID:20406889, GO:0016525=PMID:20406889, GO:0060389=PMID:17068149, GO:0008156=PMID:20406889, GO:0045893=PMID:17068149, GO:0008083=GO_REF:0000037, GO:0040007=GO_REF:0000002, GO:0045603=GO_REF:0000019, GO:0001570=GO_REF:0000019, GO:0043537=PMID:20406889} Q9UK05 Growth/differentiation factor 2 protein 20120314 {GO:0005515=IPI, GO:0030308=IDA, GO:0051216=TAS, GO:0048514=IDA, GO:0005615=IEA, GO:0032757=IDA, GO:0006879=TAS, GO:0030513=IEA, GO:0001569=IDA, GO:0010862=IDA, GO:0030509=IDA, GO:0032924=IDA, GO:0005125=IEA, GO:0001649=IEA, GO:0045766=IDA, GO:0045669=IEA, GO:0010596=IDA, GO:0001503=TAS, GO:0001938=IDA, GO:0001937=IDA, GO:0016525=TAS, GO:0060389=IDA, GO:0008156=TAS, GO:0045893=IDA, GO:0008083=IEA, GO:0040007=IEA, GO:0045603=IEA, GO:0001570=IEA, GO:0043537=TAS} BMP signaling pathway, activin receptor signaling pathway, blood vessel morphogenesis, cartilage development, cellular iron ion homeostasis, growth, negative regulation of DNA replication, negative regulation of angiogenesis, negative regulation of blood vessel endothelial cell migration, negative regulation of cell growth, negative regulation of endothelial cell migration, negative regulation of endothelial cell proliferation, ossification, osteoblast differentiation, pathway-restricted SMAD protein phosphorylation, patterning of blood vessels, positive regulation of BMP signaling pathway, positive regulation of angiogenesis, positive regulation of endothelial cell differentiation, positive regulation of endothelial cell proliferation, positive regulation of interleukin-8 production, positive regulation of osteoblast differentiation, positive regulation of pathway-restricted SMAD protein phosphorylation, positive regulation of transcription, DNA-dependent, vasculogenesis extracellular space cytokine activity, growth factor activity, protein binding Human GDF5 Reactome UniProtKB {GO:0035137=GO_REF:0000019, GO:0035136=GO_REF:0000019, GO:0051216=GO_REF:0000037, GO:0007267=PMID:8589725, GO:0005576=Reactome:REACT_150165, GO:0042981=GO_REF:0000019, GO:0030326=GO_REF:0000019, GO:0005125=GO_REF:0000037, GO:0005615=GO_REF:0000037, GO:0030198=Reactome:REACT_118779, GO:0040014=GO_REF:0000019, GO:0032332=GO_REF:0000019, GO:0007179=PMID:7961761, GO:0040007=GO_REF:0000002, GO:0008083=GO_REF:0000037} P43026 Growth/differentiation factor 5 protein 20130301 {GO:0035137=IEA, GO:0035136=IEA, GO:0051216=IEA, GO:0007267=TAS, GO:0005576=TAS, GO:0042981=IEA, GO:0030326=IEA, GO:0005125=IEA, GO:0005615=IEA, GO:0030198=TAS, GO:0040014=IEA, GO:0032332=IEA, GO:0007179=TAS, GO:0040007=IEA, GO:0008083=IEA} cartilage development, cell-cell signaling, embryonic limb morphogenesis, extracellular matrix organization, forelimb morphogenesis, growth, hindlimb morphogenesis, positive regulation of chondrocyte differentiation, regulation of apoptotic process, regulation of multicellular organism growth, transforming growth factor beta receptor signaling pathway extracellular region, extracellular space cytokine activity, growth factor activity Human GDF6 BHF-UCL UniProtKB {GO:0045666=GO_REF:0000019, GO:0010862=PMID:16049014, GO:0060389=PMID:16049014, GO:0030509=PMID:16049014, GO:0045893=PMID:16049014, GO:0032924=PMID:16049014, GO:0008083=GO_REF:0000037, GO:0005615=GO_REF:0000037, GO:0005125=GO_REF:0000037, GO:0040007=GO_REF:0000002, GO:0042803=GO_REF:0000019} Q6KF10 Growth/differentiation factor 6 protein 20090114 {GO:0045666=IEA, GO:0010862=IDA, GO:0060389=IDA, GO:0030509=IDA, GO:0045893=IDA, GO:0032924=IDA, GO:0008083=IEA, GO:0005615=IEA, GO:0005125=IEA, GO:0040007=IEA, GO:0042803=IEA} BMP signaling pathway, activin receptor signaling pathway, growth, pathway-restricted SMAD protein phosphorylation, positive regulation of neuron differentiation, positive regulation of pathway-restricted SMAD protein phosphorylation, positive regulation of transcription, DNA-dependent extracellular space cytokine activity, growth factor activity, protein homodimerization activity Human GDF7 BHF-UCL UniProtKB {GO:0005515=PMID:16049014, GO:0010862=PMID:16049014, GO:0021509=GO_REF:0000019, GO:0030509=PMID:16049014, GO:0060571=GO_REF:0000019, GO:0032924=PMID:16049014, GO:0005125=GO_REF:0000037, GO:0005615=GO_REF:0000037, GO:0048853=GO_REF:0000019, GO:0021527=GO_REF:0000019, GO:0042803=GO_REF:0000019, GO:0048608=GO_REF:0000019, GO:0045165=GO_REF:0000019, GO:0007411=GO_REF:0000019, GO:0045666=GO_REF:0000019, GO:0030855=GO_REF:0000019, GO:2001051=GO_REF:0000019, GO:0030901=GO_REF:0000019, GO:0060389=PMID:16049014, GO:0048754=GO_REF:0000019, GO:0022612=GO_REF:0000019, GO:0045893=PMID:16049014, GO:0040007=GO_REF:0000002, GO:0008083=GO_REF:0000037} Q7Z4P5 Growth/differentiation factor 7 protein 20090114 {GO:0005515=IPI, GO:0010862=IDA, GO:0021509=IEA, GO:0030509=IDA, GO:0060571=IEA, GO:0032924=IDA, GO:0005125=IEA, GO:0005615=IEA, GO:0048853=IEA, GO:0021527=IEA, GO:0042803=IEA, GO:0048608=IEA, GO:0045165=IEA, GO:0007411=IEA, GO:0045666=IEA, GO:0030855=IEA, GO:2001051=IEA, GO:0030901=IEA, GO:0060389=IDA, GO:0048754=IEA, GO:0022612=IEA, GO:0045893=IDA, GO:0040007=IEA, GO:0008083=IEA} BMP signaling pathway, activin receptor signaling pathway, axon guidance, branching morphogenesis of an epithelial tube, cell fate commitment, epithelial cell differentiation, forebrain morphogenesis, gland morphogenesis, growth, midbrain development, morphogenesis of an epithelial fold, pathway-restricted SMAD protein phosphorylation, positive regulation of neuron differentiation, positive regulation of pathway-restricted SMAD protein phosphorylation, positive regulation of tendon cell differentiation, positive regulation of transcription, DNA-dependent, reproductive structure development, roof plate formation, spinal cord association neuron differentiation extracellular space cytokine activity, growth factor activity, protein binding, protein homodimerization activity Human GDF9 PINC UniProtKB {GO:0008284=PMID:19366876, GO:0030308=GO_REF:0000019, GO:2000870=PMID:20660033, GO:0007179=PMID:7760846, GO:0001555=GO_REF:0000019, GO:0007292=PMID:8849725, GO:0008083=GO_REF:0000037, GO:0005615=GO_REF:0000037, GO:0005125=GO_REF:0000037} O60383 Growth/differentiation factor 9 protein 20030904 {GO:0008284=IDA, GO:0030308=IEA, GO:2000870=IMP, GO:0007179=TAS, GO:0001555=IEA, GO:0007292=TAS, GO:0008083=IEA, GO:0005615=IEA, GO:0005125=IEA} female gamete generation, negative regulation of cell growth, oocyte growth, positive regulation of cell proliferation, regulation of progesterone secretion, transforming growth factor beta receptor signaling pathway extracellular space cytokine activity, growth factor activity Human GDI1 IntAct UniProtKB {GO:0005515=PMID:19570034, GO:0051056=Reactome:REACT_11051, GO:0043005=GO_REF:0000019, GO:0017137=GO_REF:0000019, GO:0007264=Reactome:REACT_11044, GO:0030496=PMID:15166316, GO:0015031=GO_REF:0000002, GO:0005829=Reactome:REACT_10055, GO:0043234=GO_REF:0000019, GO:0051592=GO_REF:0000019, GO:0007165=PMID:7543319, GO:0005737=GO_REF:0000054, GO:0005093=GO_REF:0000019, GO:0050771=GO_REF:0000024, GO:0005092=PMID:7849400, GO:0005096=GO_REF:0000037} P31150 Rab GDP dissociation inhibitor alpha protein 20130415 {GO:0005515=IPI, GO:0051056=TAS, GO:0043005=IEA, GO:0017137=IEA, GO:0007264=TAS, GO:0030496=IDA, GO:0015031=IEA, GO:0005829=TAS, GO:0043234=IEA, GO:0051592=IEA, GO:0007165=TAS, GO:0005737=IDA, GO:0005093=IEA, GO:0050771=ISS, GO:0005092=TAS, GO:0005096=IEA} negative regulation of axonogenesis, protein transport, regulation of small GTPase mediated signal transduction, response to calcium ion, signal transduction, small GTPase mediated signal transduction cytoplasm, cytosol, midbody, neuron projection, protein complex GDP-dissociation inhibitor activity, GTPase activator activity, Rab GDP-dissociation inhibitor activity, Rab GTPase binding, protein binding Human UniProtKB:P61027 GDI2 InterPro UniProtKB {GO:0005515=PMID:19570034, GO:0051056=Reactome:REACT_11051, GO:0007165=PMID:16130169, GO:0005737=PMID:16130169, GO:0005794=GO_REF:0000019, GO:0009986=PMID:12493773, GO:0016020=GO_REF:0000039, GO:0007264=Reactome:REACT_11044, GO:0005093=GO_REF:0000002, GO:0015031=GO_REF:0000002, GO:0005097=GO_REF:0000019, GO:0005829=Reactome:REACT_10055} Q5SX91 Rab GDP dissociation inhibitor beta protein 20130413 {GO:0005515=IPI, GO:0051056=TAS, GO:0007165=TAS, GO:0005737=TAS, GO:0005794=IEA, GO:0009986=IDA, GO:0016020=IEA, GO:0007264=TAS, GO:0005093=IEA, GO:0015031=IEA, GO:0005097=IEA, GO:0005829=TAS} protein transport, regulation of small GTPase mediated signal transduction, signal transduction, small GTPase mediated signal transduction Golgi apparatus, cell surface, cytoplasm, cytosol, membrane Rab GDP-dissociation inhibitor activity, Rab GTPase activator activity, protein binding Human InterPro:IPR000806 GDNF BHF-UCL UniProtKB {GO:0001656=GO_REF:0000024, GO:0008344=PMID:12358785, GO:0001658=GO_REF:0000024, GO:0001755=PMID:15242795, GO:0001759=GO_REF:0000019, GO:0060676=GO_REF:0000019, GO:0042803=PMID:8988018, GO:0031175=PMID:15242795, GO:0051584=PMID:8493557, GO:0043524=PMID:8493557, GO:0007411=Reactome:REACT_18266, GO:0045944=PMID:12358785, GO:0001941=GO_REF:0000019, GO:0048255=PMID:12358785, GO:0090190=PMID:17229286, GO:0043066=PMID:7830769, GO:0005102=PMID:10829012, GO:0072107=PMID:8657307, GO:0005576=PMID:9811930, GO:0060688=GO_REF:0000024, GO:0030432=GO_REF:0000024, GO:0048485=GO_REF:0000024, GO:0072108=GO_REF:0000019, GO:0048484=GO_REF:0000024, GO:0007399=PMID:8637574, GO:0021784=GO_REF:0000024, GO:0007165=PMID:7830769, GO:0003337=GO_REF:0000019, GO:0032770=PMID:12358785, GO:0008083=GO_REF:0000029, GO:0033603=PMID:12358785} P39905 Glial cell line-derived neurotrophic factor protein 20080926 {GO:0001656=ISS, GO:0008344=TAS, GO:0001658=ISS, GO:0001755=IDA, GO:0001759=IEA, GO:0060676=IEA, GO:0042803=IDA, GO:0031175=IDA, GO:0051584=IDA, GO:0043524=IDA, GO:0007411=TAS, GO:0045944=IDA, GO:0001941=IEA, GO:0048255=IDA, GO:0090190=IDA, GO:0043066=TAS, GO:0005102=TAS, GO:0072107=IDA, GO:0005576=IDA, GO:0060688=ISS, GO:0030432=ISS, GO:0048485=ISS, GO:0072108=IEA, GO:0048484=ISS, GO:0007399=TAS, GO:0021784=ISS, GO:0007165=TAS, GO:0003337=IEA, GO:0032770=IDA, GO:0008083=NAS, GO:0033603=TAS} adult locomotory behavior, axon guidance, branching involved in ureteric bud morphogenesis, enteric nervous system development, mRNA stabilization, mesenchymal to epithelial transition involved in metanephros morphogenesis, metanephros development, negative regulation of apoptotic process, negative regulation of neuron apoptotic process, nervous system development, neural crest cell migration, neuron projection development, organ induction, peristalsis, positive regulation of branching involved in ureteric bud morphogenesis, positive regulation of dopamine secretion, positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis, positive regulation of monooxygenase activity, positive regulation of transcription from RNA polymerase II promoter, positive regulation of ureteric bud formation, postganglionic parasympathetic nervous system development, postsynaptic membrane organization, regulation of dopamine uptake involved in synaptic transmission, regulation of morphogenesis of a branching structure, signal transduction, sympathetic nervous system development, ureteric bud formation extracellular region growth factor activity, protein homodimerization activity, receptor binding Human GDPD1 UniProtKB UniProtKB {GO:0006629=GO_REF:0000002, GO:0005737=GO_REF:0000039, GO:0016021=GO_REF:0000037, GO:0008889=GO_REF:0000002, GO:0006071=GO_REF:0000002, GO:0046872=GO_REF:0000037} Q8N9F7 Glycerophosphodiester phosphodiesterase domain-containing protein 1 protein 20130413 {GO:0006629=IEA, GO:0005737=IEA, GO:0016021=IEA, GO:0008889=IEA, GO:0006071=IEA, GO:0046872=IEA} glycerol metabolic process, lipid metabolic process cytoplasm, integral to membrane glycerophosphodiester phosphodiesterase activity, metal ion binding Human UniProtKB-SubCell:SL-0086 GDPD2 HPA UniProtKB {GO:0006629=GO_REF:0000002, GO:0005737=GO_REF:0000052, GO:0005886=GO_REF:0000039, GO:0047394=GO_REF:0000003, GO:0016021=GO_REF:0000037, GO:0005856=GO_REF:0000039, GO:0008889=GO_REF:0000002, GO:0006071=GO_REF:0000002, GO:0046872=GO_REF:0000037} Q9HCC8 Glycerophosphoinositol inositolphosphodiesterase GDPD2 protein 20111111 {GO:0006629=IEA, GO:0005737=IDA, GO:0005886=IEA, GO:0047394=IEA, GO:0016021=IEA, GO:0005856=IEA, GO:0008889=IEA, GO:0006071=IEA, GO:0046872=IEA} glycerol metabolic process, lipid metabolic process cytoplasm, cytoskeleton, integral to membrane, plasma membrane glycerophosphodiester phosphodiesterase activity, glycerophosphoinositol inositolphosphodiesterase activity, metal ion binding Human GDPD3 UniProtKB UniProtKB {GO:0006629=GO_REF:0000002, GO:0016021=GO_REF:0000037, GO:0008889=GO_REF:0000002, GO:0006071=GO_REF:0000002, GO:0046872=GO_REF:0000037} Q7L5L3 Glycerophosphodiester phosphodiesterase domain-containing protein 3 protein 20130413 {GO:0006629=IEA, GO:0016021=IEA, GO:0008889=IEA, GO:0006071=IEA, GO:0046872=IEA} glycerol metabolic process, lipid metabolic process integral to membrane glycerophosphodiester phosphodiesterase activity, metal ion binding Human UniProtKB-KW:KW-0479 GEM BHF-UCL UniProtKB {GO:0005515=PMID:19060904, GO:0007165=PMID:8825643, GO:0005516=GO_REF:0000037, GO:0006955=PMID:7912851, GO:0000287=PMID:17107948, GO:0007264=GO_REF:0000002, GO:0003924=PMID:17107948, GO:0009898=PMID:7912851, GO:0005634=GO_REF:0000019, GO:0005525=PMID:17107948, GO:0019003=PMID:17107948, GO:0007166=PMID:7912851} P55040 GTP-binding protein GEM protein 20090331 {GO:0005515=IPI, GO:0007165=TAS, GO:0005516=IEA, GO:0006955=TAS, GO:0000287=IDA, GO:0007264=IEA, GO:0003924=IDA, GO:0009898=IDA, GO:0005634=IEA, GO:0005525=IDA, GO:0019003=IDA, GO:0007166=TAS} cell surface receptor signaling pathway, immune response, signal transduction, small GTPase mediated signal transduction internal side of plasma membrane, nucleus GDP binding, GTP binding, GTPase activity, calmodulin binding, magnesium ion binding, protein binding Human GEMIN2 IntAct UniProtKB {GO:0008380=PMID:9323129, GO:0005515=PMID:21816274, GO:0006397=PMID:9323130, GO:0000245=GO_REF:0000002, GO:0010467=Reactome:REACT_71, GO:0015030=GO_REF:0000039, GO:0016070=Reactome:REACT_21257, GO:0005634=PMID:9323130, GO:0034660=Reactome:REACT_11052, GO:0000387=Reactome:REACT_11066, GO:0005829=Reactome:REACT_10041, GO:0005737=PMID:9323130, GO:0000375=PMID:9323129, GO:0005681=GO_REF:0000037, GO:0005654=Reactome:REACT_10010} O14893 Gem-associated protein 2 protein 20130415 {GO:0008380=TAS, GO:0005515=IPI, GO:0006397=TAS, GO:0000245=IEA, GO:0010467=TAS, GO:0015030=IEA, GO:0016070=TAS, GO:0005634=TAS, GO:0034660=TAS, GO:0000387=TAS, GO:0005829=TAS, GO:0005737=TAS, GO:0000375=TAS, GO:0005681=IEA, GO:0005654=TAS} RNA metabolic process, RNA splicing, RNA splicing, via transesterification reactions, gene expression, mRNA processing, ncRNA metabolic process, spliceosomal complex assembly, spliceosomal snRNP assembly Cajal body, cytoplasm, cytosol, nucleoplasm, nucleus, spliceosomal complex protein binding Human UniProtKB:Q16637 GEMIN4 Reactome UniProtKB {GO:0005515=PMID:12869526, GO:0010467=Reactome:REACT_71, GO:0015030=GO_REF:0000039, GO:0016070=Reactome:REACT_21257, GO:0006364=PMID:10725331, GO:0005730=GO_REF:0000039, GO:0034660=Reactome:REACT_11052, GO:0000387=Reactome:REACT_11066, GO:0005829=Reactome:REACT_10041, GO:0005737=PMID:10725331, GO:0030532=PMID:10725331, GO:0005681=GO_REF:0000037, GO:0005654=Reactome:REACT_10010} P57678 Gem-associated protein 4 protein 20130213 {GO:0005515=IPI, GO:0010467=TAS, GO:0015030=IEA, GO:0016070=TAS, GO:0006364=TAS, GO:0005730=IEA, GO:0034660=TAS, GO:0000387=TAS, GO:0005829=TAS, GO:0005737=TAS, GO:0030532=TAS, GO:0005681=IEA, GO:0005654=TAS} RNA metabolic process, gene expression, ncRNA metabolic process, rRNA processing, spliceosomal snRNP assembly Cajal body, cytoplasm, cytosol, nucleolus, nucleoplasm, small nuclear ribonucleoprotein complex, spliceosomal complex protein binding Human GEMIN5 HPA UniProtKB {GO:0005515=PMID:11714716, GO:0010467=Reactome:REACT_71, GO:0015030=GO_REF:0000039, GO:0016070=Reactome:REACT_21257, GO:0005634=GO_REF:0000052, GO:0034660=Reactome:REACT_11052, GO:0000387=Reactome:REACT_11066, GO:0005829=Reactome:REACT_10041, GO:0016604=PMID:11714716, GO:0005737=GO_REF:0000052, GO:0006461=PMID:11714716, GO:0000398=PMID:11714716, GO:0017069=PMID:16857593, GO:0005681=GO_REF:0000037, GO:0005654=Reactome:REACT_10010} Q8TEQ6 Gem-associated protein 5 protein 20110516 {GO:0005515=IPI, GO:0010467=TAS, GO:0015030=IEA, GO:0016070=TAS, GO:0005634=IDA, GO:0034660=TAS, GO:0000387=TAS, GO:0005829=TAS, GO:0016604=IDA, GO:0005737=IDA, GO:0006461=TAS, GO:0000398=TAS, GO:0017069=IDA, GO:0005681=IEA, GO:0005654=TAS} RNA metabolic process, gene expression, mRNA splicing, via spliceosome, ncRNA metabolic process, protein complex assembly, spliceosomal snRNP assembly Cajal body, cytoplasm, cytosol, nuclear body, nucleoplasm, nucleus, spliceosomal complex protein binding, snRNA binding Human GEMIN6 IntAct UniProtKB {GO:0005515=PMID:22190034, GO:0000245=GO_REF:0000002, GO:0010467=Reactome:REACT_71, GO:0015030=GO_REF:0000039, GO:0016070=Reactome:REACT_21257, GO:0005634=GO_REF:0000002, GO:0034660=Reactome:REACT_11052, GO:0000387=Reactome:REACT_11066, GO:0005829=Reactome:REACT_10041, GO:0016604=PMID:11748230, GO:0005737=PMID:11748230, GO:0000398=PMID:11748230, GO:0005681=GO_REF:0000037, GO:0005654=Reactome:REACT_10010} Q8WXD5 Gem-associated protein 6 protein 20130415 {GO:0005515=IPI, GO:0000245=IEA, GO:0010467=TAS, GO:0015030=IEA, GO:0016070=TAS, GO:0005634=IEA, GO:0034660=TAS, GO:0000387=TAS, GO:0005829=TAS, GO:0016604=IDA, GO:0005737=IDA, GO:0000398=TAS, GO:0005681=IEA, GO:0005654=TAS} RNA metabolic process, gene expression, mRNA splicing, via spliceosome, ncRNA metabolic process, spliceosomal complex assembly, spliceosomal snRNP assembly Cajal body, cytoplasm, cytosol, nuclear body, nucleoplasm, nucleus, spliceosomal complex protein binding Human UniProtKB:P12520 GEMIN7 Reactome UniProtKB {GO:0005515=PMID:12065586, GO:0010467=Reactome:REACT_71, GO:0015030=GO_REF:0000039, GO:0016070=Reactome:REACT_21257, GO:0034660=Reactome:REACT_11052, GO:0000387=Reactome:REACT_11066, GO:0005829=Reactome:REACT_10041, GO:0016604=PMID:12065586, GO:0005737=PMID:12065586, GO:0032797=GO_REF:0000002, GO:0000398=PMID:12065586, GO:0005681=GO_REF:0000037, GO:0005654=Reactome:REACT_10010} Q9H840 Gem-associated protein 7 protein 20130213 {GO:0005515=IPI, GO:0010467=TAS, GO:0015030=IEA, GO:0016070=TAS, GO:0034660=TAS, GO:0000387=TAS, GO:0005829=TAS, GO:0016604=IDA, GO:0005737=IDA, GO:0032797=IEA, GO:0000398=TAS, GO:0005681=IEA, GO:0005654=TAS} RNA metabolic process, gene expression, mRNA splicing, via spliceosome, ncRNA metabolic process, spliceosomal snRNP assembly Cajal body, SMN complex, cytoplasm, cytosol, nuclear body, nucleoplasm, spliceosomal complex protein binding Human GEMIN8 HPA UniProtKB {GO:0005515=PMID:17023415, GO:0005737=GO_REF:0000052, GO:0015030=GO_REF:0000039, GO:0032797=PMID:16434402, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0005681=GO_REF:0000037, GO:0000387=PMID:16434402} Q9NWZ8 Gem-associated protein 8 protein 20111111 {GO:0005515=IPI, GO:0005737=IDA, GO:0015030=IEA, GO:0032797=IDA, GO:0005730=IDA, GO:0005634=IDA, GO:0005681=IEA, GO:0000387=IDA} spliceosomal snRNP assembly Cajal body, SMN complex, cytoplasm, nucleolus, nucleus, spliceosomal complex protein binding Human GET4 UniProtKB UniProtKB {GO:0006810=GO_REF:0000037, GO:0071816=PMID:20676083, GO:0071818=PMID:20676083, GO:0005829=PMID:20676083} Q7L5D6 Golgi to ER traffic protein 4 homolog protein 20101105 {GO:0006810=IEA, GO:0071816=IMP, GO:0071818=IDA, GO:0005829=IDA} tail-anchored membrane protein insertion into ER membrane, transport BAT3 complex, cytosol Human GFAP Reactome UniProtKB {GO:0005882=GO_REF:0000019, GO:0045109=GO_REF:0000019, GO:0031102=GO_REF:0000019, GO:0009611=GO_REF:0000019, GO:0060291=GO_REF:0000019, GO:0051580=GO_REF:0000019, GO:0042995=GO_REF:0000019, GO:0044297=GO_REF:0000019, GO:0005829=Reactome:REACT_115713, GO:0005737=PMID:12355421, GO:0005178=GO_REF:0000019, GO:0010625=GO_REF:0000019, GO:0016020=GO_REF:0000019, GO:0014002=GO_REF:0000019, GO:0030198=GO_REF:0000019, GO:0005198=GO_REF:0000002, GO:0060020=GO_REF:0000019, GO:0005200=GO_REF:0000019, GO:0010977=GO_REF:0000019, GO:0019900=GO_REF:0000019} P14136 Glial fibrillary acidic protein protein 20110427 {GO:0005882=IEA, GO:0045109=IEA, GO:0031102=IEA, GO:0009611=IEA, GO:0060291=IEA, GO:0051580=IEA, GO:0042995=IEA, GO:0044297=IEA, GO:0005829=TAS, GO:0005737=IDA, GO:0005178=IEA, GO:0010625=IEA, GO:0016020=IEA, GO:0014002=IEA, GO:0030198=IEA, GO:0005198=IEA, GO:0060020=IEA, GO:0005200=IEA, GO:0010977=IEA, GO:0019900=IEA} Bergmann glial cell differentiation, astrocyte development, extracellular matrix organization, intermediate filament organization, long-term synaptic potentiation, negative regulation of neuron projection development, neuron projection regeneration, positive regulation of Schwann cell proliferation, regulation of neurotransmitter uptake, response to wounding cell body, cell projection, cytoplasm, cytosol, intermediate filament, membrane integrin binding, kinase binding, structural constituent of cytoskeleton, structural molecule activity Human GFER HPA UniProtKB {GO:0005515=PMID:12681488, GO:0008283=GO_REF:0000029, GO:0050660=PMID:22224850, GO:0006626=Reactome:REACT_118595, GO:0015035=PMID:22224850, GO:0005576=GO_REF:0000039, GO:0007283=GO_REF:0000029, GO:0005575=GO_REF:0000015, GO:0005739=GO_REF:0000052, GO:0005758=GO_REF:0000039, GO:0005737=GO_REF:0000052, GO:0016972=GO_REF:0000003, GO:0008083=GO_REF:0000037, GO:0044267=Reactome:REACT_17015} P55789 FAD-linked sulfhydryl oxidase ALR protein 20111111 {GO:0005515=IPI, GO:0008283=NAS, GO:0050660=IDA, GO:0006626=TAS, GO:0015035=IDA, GO:0005576=IEA, GO:0007283=NAS, GO:0005575=ND, GO:0005739=IDA, GO:0005758=IEA, GO:0005737=IDA, GO:0016972=IEA, GO:0008083=IEA, GO:0044267=TAS} cell proliferation, cellular protein metabolic process, protein targeting to mitochondrion, spermatogenesis cellular_component, cytoplasm, extracellular region, mitochondrial intermembrane space, mitochondrion flavin adenine dinucleotide binding, growth factor activity, protein binding, protein disulfide oxidoreductase activity, thiol oxidase activity Human GFI1 BHF-UCL UniProtKB {GO:0005515=PMID:21570500, GO:0044212=PMID:15947108, GO:0009996=GO_REF:0000019, GO:0034121=PMID:20547752, GO:0005634=PMID:12874834, GO:0042660=GO_REF:0000019, GO:0016363=PMID:12874834, GO:0000083=PMID:8441411, GO:0017053=PMID:12874834, GO:0070105=PMID:11060035, GO:0016032=PMID:8441411, GO:0042472=GO_REF:0000019, GO:0042491=GO_REF:0000019, GO:0032088=GO_REF:0000024, GO:0000122=PMID:15947108, GO:0006351=GO_REF:0000037, GO:0016604=PMID:11060035, GO:0071222=PMID:20547752, GO:0045165=GO_REF:0000019, GO:0010977=PMID:19026687, GO:0008270=GO_REF:0000002, GO:0007638=GO_REF:0000019, GO:0045892=PMID:12874834, GO:0010956=PMID:15947108, GO:0010957=PMID:15947108} Q99684 Zinc finger protein Gfi-1 protein 20090407 {GO:0005515=IPI, GO:0044212=IDA, GO:0009996=IEA, GO:0034121=IDA, GO:0005634=IDA, GO:0042660=IEA, GO:0016363=IDA, GO:0000083=TAS, GO:0017053=IDA, GO:0070105=IDA, GO:0016032=TAS, GO:0042472=IEA, GO:0042491=IEA, GO:0032088=ISS, GO:0000122=IDA, GO:0006351=IEA, GO:0016604=IDA, GO:0071222=IEP, GO:0045165=IEA, GO:0010977=IDA, GO:0008270=IEA, GO:0007638=IEA, GO:0045892=IDA, GO:0010956=IDA, GO:0010957=IC} auditory receptor cell differentiation, cell fate commitment, cellular response to lipopolysaccharide, inner ear morphogenesis, mechanosensory behavior, negative regulation of NF-kappaB transcription factor activity, negative regulation of calcidiol 1-monooxygenase activity, negative regulation of cell fate specification, negative regulation of neuron projection development, negative regulation of transcription from RNA polymerase II promoter, negative regulation of transcription, DNA-dependent, negative regulation of vitamin D biosynthetic process, positive regulation of cell fate specification, positive regulation of interleukin-6-mediated signaling pathway, regulation of toll-like receptor signaling pathway, regulation of transcription involved in G1/S phase of mitotic cell cycle, transcription, DNA-dependent, viral reproduction nuclear body, nuclear matrix, nucleus, transcriptional repressor complex protein binding, transcription regulatory region DNA binding, zinc ion binding Human GFI1B BHF-UCL UniProtKB {GO:0005515=PMID:16713569, GO:0005667=PMID:15920471, GO:0006366=PMID:9566867, GO:0008283=PMID:9566867, GO:0007275=GO_REF:0000037, GO:0005634=PMID:12874834, GO:0000122=PMID:9566867, GO:0003677=GO_REF:0000037, GO:0016363=PMID:12874834, GO:0000114=PMID:9566867, GO:0001085=PMID:15920471, GO:0008270=GO_REF:0000002, GO:0016568=GO_REF:0000037} Q5VTD9 Zinc finger protein Gfi-1b protein 20110810 {GO:0005515=IPI, GO:0005667=IDA, GO:0006366=TAS, GO:0008283=TAS, GO:0007275=IEA, GO:0005634=IDA, GO:0000122=TAS, GO:0003677=IEA, GO:0016363=IDA, GO:0000114=TAS, GO:0001085=IPI, GO:0008270=IEA, GO:0016568=IEA} cell proliferation, chromatin modification, multicellular organismal development, negative regulation of transcription from RNA polymerase II promoter, regulation of transcription involved in G1 phase of mitotic cell cycle, transcription from RNA polymerase II promoter nuclear matrix, nucleus, transcription factor complex DNA binding, RNA polymerase II transcription factor binding, protein binding, zinc ion binding Human GFM1 UniProtKB UniProtKB {GO:0006184=PMID:19716793, GO:0005739=GO_REF:0000039, GO:0005622=GO_REF:0000002, GO:0070125=PMID:19716793, GO:0003924=PMID:19716793, GO:0005525=GO_REF:0000037, GO:0003746=GO_REF:0000038} Q9H9M0 Elongation factor G, mitochondrial protein 20130413 {GO:0006184=IDA, GO:0005739=IEA, GO:0005622=IEA, GO:0070125=IDA, GO:0003924=IDA, GO:0005525=IEA, GO:0003746=IEA} GTP catabolic process, mitochondrial translational elongation intracellular, mitochondrion GTP binding, GTPase activity, translation elongation factor activity Human UniProtKB-KW:KW-0251 GFM2 GOC UniProtKB {GO:0006184=PMID:19716793, GO:0005739=GO_REF:0000039, GO:0070125=PMID:19716793, GO:0032543=PMID:19716793, GO:0003924=PMID:19716793, GO:0032790=PMID:19716793, GO:0003746=PMID:19716793, GO:0005525=GO_REF:0000037} Q969S9 Ribosome-releasing factor 2, mitochondrial protein 20130413 {GO:0006184=IDA, GO:0005739=IEA, GO:0070125=IDA, GO:0032543=IDA, GO:0003924=IDA, GO:0032790=IDA, GO:0003746=IDA, GO:0005525=IEA} GTP catabolic process, mitochondrial translation, mitochondrial translational elongation, ribosome disassembly mitochondrion GTP binding, GTPase activity, translation elongation factor activity Human GFOD1 UniProtKB UniProtKB {GO:0016491=GO_REF:0000037, GO:0005576=GO_REF:0000039} Q9NXC2 Glucose-fructose oxidoreductase domain-containing protein 1 protein 20130413 {GO:0016491=IEA, GO:0005576=IEA} extracellular region oxidoreductase activity Human UniProtKB-SubCell:SL-0243 GFOD2 UniProtKB UniProtKB {GO:0030198=GO_REF:0000019, GO:0005578=GO_REF:0000039, GO:0016491=GO_REF:0000037} Q3B7J2 Glucose-fructose oxidoreductase domain-containing protein 2 protein 20130413 {GO:0030198=IEA, GO:0005578=IEA, GO:0016491=IEA} extracellular matrix organization proteinaceous extracellular matrix oxidoreductase activity Human UniProtKB-SubCell:SL-0111 GFPT1 Reactome UniProtKB {GO:0004360=GO_REF:0000003, GO:0032869=GO_REF:0000019, GO:0006042=GO_REF:0000019, GO:0006048=Reactome:REACT_22394, GO:0045719=GO_REF:0000019, GO:0030968=Reactome:REACT_18356, GO:0005829=Reactome:REACT_115595, GO:0016051=GO_REF:0000002, GO:0006112=PMID:1460020, GO:0009744=GO_REF:0000019, GO:0051289=GO_REF:0000019, GO:0030246=GO_REF:0000002, GO:0006987=Reactome:REACT_18368, GO:0006488=Reactome:REACT_22433, GO:0044267=Reactome:REACT_17015, GO:0006002=GO_REF:0000019, GO:0016597=GO_REF:0000019, GO:0043687=Reactome:REACT_22161, GO:0018279=Reactome:REACT_22426, GO:0006541=GO_REF:0000037} Q06210 "Glutamine--fructose-6-phosphate aminotransferase ""isomerizing"" 1" protein 20130301 {GO:0004360=IEA, GO:0032869=IEA, GO:0006042=IEA, GO:0006048=TAS, GO:0045719=IEA, GO:0030968=TAS, GO:0005829=TAS, GO:0016051=IEA, GO:0006112=TAS, GO:0009744=IEA, GO:0051289=IEA, GO:0030246=IEA, GO:0006987=TAS, GO:0006488=TAS, GO:0044267=TAS, GO:0006002=IEA, GO:0016597=IEA, GO:0043687=TAS, GO:0018279=TAS, GO:0006541=IEA} UDP-N-acetylglucosamine biosynthetic process, activation of signaling protein activity involved in unfolded protein response, carbohydrate biosynthetic process, cellular protein metabolic process, cellular response to insulin stimulus, dolichol-linked oligosaccharide biosynthetic process, endoplasmic reticulum unfolded protein response, energy reserve metabolic process, fructose 6-phosphate metabolic process, glucosamine biosynthetic process, glutamine metabolic process, negative regulation of glycogen biosynthetic process, post-translational protein modification, protein N-linked glycosylation via asparagine, protein homotetramerization, response to sucrose stimulus cytosol amino acid binding, carbohydrate binding, glutamine-fructose-6-phosphate transaminase (isomerizing) activity Human GFPT2 Reactome UniProtKB {GO:0004360=GO_REF:0000003, GO:0006048=Reactome:REACT_22394, GO:0005829=Reactome:REACT_22115, GO:0016051=GO_REF:0000002, GO:0006112=PMID:10198162, GO:0008152=GO_REF:0000002, GO:0030246=GO_REF:0000002, GO:0006488=Reactome:REACT_22433, GO:0006002=PMID:10198162, GO:0044267=Reactome:REACT_17015, GO:0006541=GO_REF:0000037, GO:0018279=Reactome:REACT_22426, GO:0043687=Reactome:REACT_22161} O94808 "Glutamine--fructose-6-phosphate aminotransferase ""isomerizing"" 2" protein 20130301 {GO:0004360=IEA, GO:0006048=TAS, GO:0005829=TAS, GO:0016051=IEA, GO:0006112=TAS, GO:0008152=IEA, GO:0030246=IEA, GO:0006488=TAS, GO:0006002=TAS, GO:0044267=TAS, GO:0006541=IEA, GO:0018279=TAS, GO:0043687=TAS} UDP-N-acetylglucosamine biosynthetic process, carbohydrate biosynthetic process, cellular protein metabolic process, dolichol-linked oligosaccharide biosynthetic process, energy reserve metabolic process, fructose 6-phosphate metabolic process, glutamine metabolic process, metabolic process, post-translational protein modification, protein N-linked glycosylation via asparagine cytosol carbohydrate binding, glutamine-fructose-6-phosphate transaminase (isomerizing) activity Human GFRA1 GOC UniProtKB {GO:0030424=GO_REF:0000019, GO:0001822=GO_REF:0000019, GO:0005102=PMID:9545641, GO:0035860=PMID:10829012, GO:0031225=GO_REF:0000037, GO:0005615=GO_REF:0000019, GO:0043235=GO_REF:0000019, GO:0005178=GO_REF:0000019, GO:0016167=PMID:10829012, GO:0016477=GO_REF:0000019, GO:0007411=Reactome:REACT_18266, GO:0043025=GO_REF:0000019, GO:0004872=GO_REF:0000029, GO:0009897=GO_REF:0000019, GO:0007166=PMID:8674117, GO:0008584=GO_REF:0000019, GO:0019898=GO_REF:0000029} P56159 GDNF family receptor alpha-1 protein 20130413 {GO:0030424=IEA, GO:0001822=IEA, GO:0005102=TAS, GO:0035860=TAS, GO:0031225=IEA, GO:0005615=IEA, GO:0043235=IEA, GO:0005178=IEA, GO:0016167=TAS, GO:0016477=IEA, GO:0007411=TAS, GO:0043025=IEA, GO:0004872=NAS, GO:0009897=IEA, GO:0007166=NAS, GO:0008584=IEA, GO:0019898=NAS} axon guidance, cell migration, cell surface receptor signaling pathway, glial cell-derived neurotrophic factor receptor signaling pathway, kidney development, male gonad development anchored to membrane, axon, external side of plasma membrane, extracellular space, extrinsic to membrane, neuronal cell body, receptor complex glial cell-derived neurotrophic factor receptor activity, integrin binding, receptor activity, receptor binding Human GFRA2 GOC UniProtKB {GO:0016167=PMID:10829012, GO:0005886=GO_REF:0000039, GO:0035860=PMID:10829012, GO:0004872=GO_REF:0000002, GO:0031225=GO_REF:0000037, GO:0007169=PMID:9192898, GO:0019898=PMID:10829012, GO:0007399=GO_REF:0000019} O00451 GDNF family receptor alpha-2 protein 20130413 {GO:0016167=TAS, GO:0005886=IEA, GO:0035860=TAS, GO:0004872=IEA, GO:0031225=IEA, GO:0007169=TAS, GO:0019898=TAS, GO:0007399=IEA} glial cell-derived neurotrophic factor receptor signaling pathway, nervous system development, transmembrane receptor protein tyrosine kinase signaling pathway anchored to membrane, extrinsic to membrane, plasma membrane glial cell-derived neurotrophic factor receptor activity, receptor activity Human GFRA3 HPA UniProtKB {GO:0005886=GO_REF:0000052, GO:0005102=PMID:9407096, GO:0031225=GO_REF:0000037, GO:0048485=GO_REF:0000019, GO:0007399=PMID:9490034, GO:0043231=GO_REF:0000052, GO:0007165=PMID:9576965, GO:0005737=GO_REF:0000052, GO:0007422=PMID:9576965, GO:0001764=GO_REF:0000019, GO:0008046=GO_REF:0000019, GO:0009897=GO_REF:0000019, GO:0019898=PMID:9490034} O60609 GDNF family receptor alpha-3 protein 20101115 {GO:0005886=IDA, GO:0005102=TAS, GO:0031225=IEA, GO:0048485=IEA, GO:0007399=TAS, GO:0043231=IDA, GO:0007165=TAS, GO:0005737=IDA, GO:0007422=TAS, GO:0001764=IEA, GO:0008046=IEA, GO:0009897=IEA, GO:0019898=TAS} nervous system development, neuron migration, peripheral nervous system development, signal transduction, sympathetic nervous system development anchored to membrane, cytoplasm, external side of plasma membrane, extrinsic to membrane, intracellular membrane-bounded organelle, plasma membrane axon guidance receptor activity, receptor binding Human GFRA4 UniProtKB UniProtKB {GO:0030279=GO_REF:0000019, GO:0005886=GO_REF:0000039, GO:0016167=GO_REF:0000019, GO:0031225=GO_REF:0000037, GO:0005615=GO_REF:0000019} Q9GZZ7 GDNF family receptor alpha-4 protein 20130413 {GO:0030279=IEA, GO:0005886=IEA, GO:0016167=IEA, GO:0031225=IEA, GO:0005615=IEA} negative regulation of ossification anchored to membrane, extracellular space, plasma membrane glial cell-derived neurotrophic factor receptor activity Human UniProtKB-SubCell:SL-0039 GFRAL ENSEMBL UniProtKB {GO:0043066=GO_REF:0000019, GO:0005886=GO_REF:0000019, GO:0016021=GO_REF:0000037, GO:0031098=GO_REF:0000019} Q6UXV0 GDNF family receptor alpha-like protein 20130413 {GO:0043066=IEA, GO:0005886=IEA, GO:0016021=IEA, GO:0031098=IEA} negative regulation of apoptotic process, stress-activated protein kinase signaling cascade integral to membrane, plasma membrane Human Ensembl:ENSMUSP00000074421 GGA1 IntAct UniProtKB {GO:0005515=PMID:20676133, GO:0005622=GO_REF:0000002, GO:0003674=GO_REF:0000015, GO:0030131=GO_REF:0000002, GO:0005794=PMID:20214818, GO:0016192=GO_REF:0000002, GO:0006886=PMID:20211637, GO:0010008=GO_REF:0000039} Q9UJY5 ADP-ribosylation factor-binding protein GGA1 protein 20130415 {GO:0005515=IPI, GO:0005622=IEA, GO:0003674=ND, GO:0030131=IEA, GO:0005794=TAS, GO:0016192=IEA, GO:0006886=TAS, GO:0010008=IEA} intracellular protein transport, vesicle-mediated transport Golgi apparatus, clathrin adaptor complex, endosome membrane, intracellular molecular_function, protein binding Human UniProtKB:Q9Y3C5 GGA2 BHF-UCL UniProtKB {GO:0005515=PMID:12429846, GO:0005802=PMID:10749927, GO:0005622=GO_REF:0000002, GO:0030131=GO_REF:0000002, GO:0005794=GO_REF:0000039, GO:0030306=PMID:10749927, GO:0030136=PMID:19478182, GO:0016192=GO_REF:0000002, GO:0006886=PMID:10749927, GO:0010008=GO_REF:0000039} Q9UJY4 ADP-ribosylation factor-binding protein GGA2 protein 20110126 {GO:0005515=IPI, GO:0005802=IDA, GO:0005622=IEA, GO:0030131=IEA, GO:0005794=IEA, GO:0030306=IDA, GO:0030136=IDA, GO:0016192=IEA, GO:0006886=NAS, GO:0010008=IEA} intracellular protein transport, vesicle-mediated transport Golgi apparatus, clathrin adaptor complex, clathrin-coated vesicle, endosome membrane, intracellular, trans-Golgi network ADP-ribosylation factor binding, protein binding Human UniProtKB:Q14677 GGA3 IntAct UniProtKB {GO:0005515=PMID:15039775, GO:0005802=PMID:10749927, GO:0030131=GO_REF:0000002, GO:0005794=GO_REF:0000039, GO:0030306=PMID:10749927, GO:0016192=GO_REF:0000002, GO:0006886=PMID:10749927, GO:0010008=GO_REF:0000039} Q9NZ52 ADP-ribosylation factor-binding protein GGA3 protein 20130415 {GO:0005515=IPI, GO:0005802=IDA, GO:0030131=IEA, GO:0005794=IEA, GO:0030306=IDA, GO:0016192=IEA, GO:0006886=NAS, GO:0010008=IEA} intracellular protein transport, vesicle-mediated transport Golgi apparatus, clathrin adaptor complex, endosome membrane, trans-Golgi network ADP-ribosylation factor binding, protein binding Human UniProtKB:P0CG47 GGCT Reactome UniProtKB {GO:0003839=Reactome:REACT_75929, GO:0006805=Reactome:REACT_13433, GO:0006750=Reactome:REACT_6960, GO:0001836=PMID:16765912, GO:0044281=Reactome:REACT_111217, GO:0042803=PMID:17932939, GO:0005829=Reactome:REACT_75929} O75223 Gamma-glutamylcyclotransferase protein 20110408 {GO:0003839=TAS, GO:0006805=TAS, GO:0006750=TAS, GO:0001836=IMP, GO:0044281=TAS, GO:0042803=IDA, GO:0005829=TAS} glutathione biosynthetic process, release of cytochrome c from mitochondria, small molecule metabolic process, xenobiotic metabolic process cytosol gamma-glutamylcyclotransferase activity, protein homodimerization activity Human GGCX Reactome UniProtKB {GO:0017187=Reactome:REACT_1132, GO:0016020=PMID:1749935, GO:0007596=PMID:9845520, GO:0008488=GO_REF:0000002, GO:0005789=Reactome:REACT_2045, GO:0016021=GO_REF:0000037, GO:0044267=Reactome:REACT_17015, GO:0006464=PMID:1749935, GO:0043687=Reactome:REACT_22161} P38435 Vitamin K-dependent gamma-carboxylase protein 20130301 {GO:0017187=TAS, GO:0016020=TAS, GO:0007596=TAS, GO:0008488=IEA, GO:0005789=TAS, GO:0016021=IEA, GO:0044267=TAS, GO:0006464=TAS, GO:0043687=TAS} blood coagulation, cellular protein metabolic process, cellular protein modification process, peptidyl-glutamic acid carboxylation, post-translational protein modification endoplasmic reticulum membrane, integral to membrane, membrane gamma-glutamyl carboxylase activity Human GGH PINC UniProtKB {GO:0042470=GO_REF:0000039, GO:0032868=GO_REF:0000019, GO:0034722=PMID:11005824, GO:0045471=GO_REF:0000019, GO:0042493=GO_REF:0000019, GO:0008242=PMID:8816764, GO:0005764=GO_REF:0000039, GO:0010043=GO_REF:0000019, GO:0005615=GO_REF:0000039, GO:0008238=PMID:8816764, GO:0005829=GO_REF:0000019, GO:0006541=GO_REF:0000002} Q92820 Gamma-glutamyl hydrolase protein 20030904 {GO:0042470=IEA, GO:0032868=IEA, GO:0034722=IDA, GO:0045471=IEA, GO:0042493=IEA, GO:0008242=TAS, GO:0005764=IEA, GO:0010043=IEA, GO:0005615=IEA, GO:0008238=TAS, GO:0005829=IEA, GO:0006541=IEA} glutamine metabolic process, response to drug, response to ethanol, response to insulin stimulus, response to zinc ion cytosol, extracellular space, lysosome, melanosome exopeptidase activity, gamma-glutamyl-peptidase activity, omega peptidase activity Human GGN UniProtKB UniProtKB {GO:0048471=GO_REF:0000019, GO:0008104=GO_REF:0000019, GO:0007276=GO_REF:0000024, GO:0046983=GO_REF:0000019, GO:0005730=GO_REF:0000019, GO:0007275=GO_REF:0000037, GO:0007283=GO_REF:0000037, GO:0030154=GO_REF:0000037} Q86UU5 Gametogenetin protein 20061106 {GO:0048471=IEA, GO:0008104=IEA, GO:0007276=ISS, GO:0046983=IEA, GO:0005730=IEA, GO:0007275=IEA, GO:0007283=IEA, GO:0030154=IEA} cell differentiation, gamete generation, multicellular organismal development, protein localization, spermatogenesis nucleolus, perinuclear region of cytoplasm protein dimerization activity Human UniProtKB:Q80WJ1 GGNBP2 UniProtKB UniProtKB {GO:0016023=GO_REF:0000039, GO:0005634=GO_REF:0000019, GO:0007275=GO_REF:0000037, GO:0007283=GO_REF:0000037, GO:0030154=GO_REF:0000037} Q9H3C7 Gametogenetin-binding protein 2 protein 20130413 {GO:0016023=IEA, GO:0005634=IEA, GO:0007275=IEA, GO:0007283=IEA, GO:0030154=IEA} cell differentiation, multicellular organismal development, spermatogenesis cytoplasmic membrane-bounded vesicle, nucleus Human UniProtKB-SubCell:SL-0088 GGPS1 Reactome UniProtKB {GO:0006695=Reactome:REACT_9405, GO:0045337=GO_REF:0000041, GO:0033386=GO_REF:0000041, GO:0004337=GO_REF:0000003, GO:0004161=GO_REF:0000003, GO:0033384=GO_REF:0000041, GO:0044281=Reactome:REACT_111217, GO:0008299=GO_REF:0000038, GO:0004311=PMID:10026212, GO:0006720=PMID:10026212, GO:0046872=GO_REF:0000037, GO:0005829=Reactome:REACT_147826} O95749 Geranylgeranyl pyrophosphate synthase protein 20130213 {GO:0006695=TAS, GO:0045337=IEA, GO:0033386=IEA, GO:0004337=IEA, GO:0004161=IEA, GO:0033384=IEA, GO:0044281=TAS, GO:0008299=IEA, GO:0004311=IDA, GO:0006720=IDA, GO:0046872=IEA, GO:0005829=TAS} cholesterol biosynthetic process, farnesyl diphosphate biosynthetic process, geranyl diphosphate biosynthetic process, geranylgeranyl diphosphate biosynthetic process, isoprenoid biosynthetic process, isoprenoid metabolic process, small molecule metabolic process cytosol dimethylallyltranstransferase activity, farnesyltranstransferase activity, geranyltranstransferase activity, metal ion binding Human GGT1 Reactome UniProtKB {GO:0019369=Reactome:REACT_147851, GO:0005515=PMID:15528406, GO:0006520=PMID:2904146, GO:0019370=PMID:14754911, GO:0019344=GO_REF:0000024, GO:0006805=Reactome:REACT_13433, GO:0005886=Reactome:REACT_75920, GO:0050727=GO_REF:0000024, GO:0006749=PMID:18357469, GO:0002682=GO_REF:0000024, GO:0044281=Reactome:REACT_111217, GO:0007283=GO_REF:0000024, GO:0006691=Reactome:REACT_150420, GO:0031362=PMID:18357469, GO:0016787=GO_REF:0000037, GO:0016020=GO_REF:0000029, GO:0003840=PMID:18357469, GO:0006750=Reactome:REACT_6960, GO:0016021=GO_REF:0000037} P19440 Gamma-glutamyltranspeptidase 1 protein 20120224 {GO:0019369=TAS, GO:0005515=IPI, GO:0006520=TAS, GO:0019370=IMP, GO:0019344=ISS, GO:0006805=TAS, GO:0005886=TAS, GO:0050727=ISS, GO:0006749=TAS, GO:0002682=ISS, GO:0044281=TAS, GO:0007283=ISS, GO:0006691=TAS, GO:0031362=TAS, GO:0016787=IEA, GO:0016020=NAS, GO:0003840=TAS, GO:0006750=TAS, GO:0016021=IEA} arachidonic acid metabolic process, cellular amino acid metabolic process, cysteine biosynthetic process, glutathione biosynthetic process, glutathione metabolic process, leukotriene biosynthetic process, leukotriene metabolic process, regulation of immune system process, regulation of inflammatory response, small molecule metabolic process, spermatogenesis, xenobiotic metabolic process anchored to external side of plasma membrane, integral to membrane, membrane, plasma membrane gamma-glutamyltransferase activity, hydrolase activity, protein binding Human GGT7 UniProtKB UniProtKB {GO:0019370=GO_REF:0000024, GO:0016787=GO_REF:0000037, GO:0003840=PMID:18357469, GO:0006750=GO_REF:0000037, GO:0006749=PMID:18357469, GO:0016021=GO_REF:0000037, GO:0031362=PMID:18357469} Q9UJ14 Gamma-glutamyltransferase 7 protein 20110915 {GO:0019370=ISS, GO:0016787=IEA, GO:0003840=TAS, GO:0006750=IEA, GO:0006749=TAS, GO:0016021=IEA, GO:0031362=TAS} glutathione biosynthetic process, glutathione metabolic process, leukotriene biosynthetic process anchored to external side of plasma membrane, integral to membrane gamma-glutamyltransferase activity, hydrolase activity Human GGTLC1 UniProtKB UniProtKB {GO:0019370=GO_REF:0000024, GO:0003840=PMID:18357469, GO:0006749=PMID:18357469, GO:0031362=PMID:18357469} Q9BX51 Gamma-glutamyltransferase light chain 1 protein 20110915 {GO:0019370=ISS, GO:0003840=TAS, GO:0006749=TAS, GO:0031362=TAS} glutathione metabolic process, leukotriene biosynthetic process anchored to external side of plasma membrane gamma-glutamyltransferase activity Human GH1 BHF-UCL UniProtKB {GO:0005515=PMID:9353194, GO:0010535=PMID:12552091, GO:0005148=PMID:7984244, GO:0042517=PMID:12552091, GO:0005131=PMID:1549776, GO:0050731=PMID:7782332, GO:0042523=PMID:8923468, GO:0014068=PMID:7782332, GO:0060396=PMID:8063815, GO:0005576=Reactome:REACT_116060, GO:0060397=Reactome:REACT_111133, GO:0070977=PMID:20110402, GO:0005615=PMID:11549663, GO:0007259=PMID:8063815, GO:0046872=GO_REF:0000037, GO:0046427=PMID:8923468, GO:0005179=GO_REF:0000037, GO:0015758=PMID:9144201, GO:0043568=PMID:7565946, GO:0043406=PMID:8063815, GO:0040018=PMID:8496314, GO:0032355=PMID:12552091, GO:0008083=PMID:9360546, GO:0002092=PMID:9360546} P01241 Somatotropin protein 20081205 {GO:0005515=IPI, GO:0010535=IDA, GO:0005148=IPI, GO:0042517=IDA, GO:0005131=IPI, GO:0050731=IDA, GO:0042523=IDA, GO:0014068=IDA, GO:0060396=IDA, GO:0005576=TAS, GO:0060397=TAS, GO:0070977=IDA, GO:0005615=IDA, GO:0007259=IDA, GO:0046872=IEA, GO:0046427=IDA, GO:0005179=IEA, GO:0015758=IDA, GO:0043568=IDA, GO:0043406=TAS, GO:0040018=IMP, GO:0032355=IDA, GO:0008083=IPI, GO:0002092=IDA} JAK-STAT cascade, JAK-STAT cascade involved in growth hormone signaling pathway, bone maturation, glucose transport, growth hormone receptor signaling pathway, positive regulation of JAK-STAT cascade, positive regulation of MAP kinase activity, positive regulation of activation of JAK2 kinase activity, positive regulation of insulin-like growth factor receptor signaling pathway, positive regulation of multicellular organism growth, positive regulation of peptidyl-tyrosine phosphorylation, positive regulation of phosphatidylinositol 3-kinase cascade, positive regulation of receptor internalization, positive regulation of tyrosine phosphorylation of Stat3 protein, positive regulation of tyrosine phosphorylation of Stat5 protein, response to estradiol stimulus extracellular region, extracellular space growth factor activity, growth hormone receptor binding, hormone activity, metal ion binding, prolactin receptor binding, protein binding Human UniProtKB:P10912 GH2 Reactome UniProtKB {GO:0005179=GO_REF:0000037, GO:0005576=Reactome:REACT_116060, GO:0060397=Reactome:REACT_111133} P01242 Growth hormone variant protein 20130301 {GO:0005179=IEA, GO:0005576=TAS, GO:0060397=TAS} JAK-STAT cascade involved in growth hormone signaling pathway extracellular region hormone activity Human GHITM IntAct UniProtKB {GO:0005515=PMID:21903422, GO:0008150=GO_REF:0000015, GO:0003674=GO_REF:0000015, GO:0005743=GO_REF:0000039, GO:0006915=GO_REF:0000037, GO:0016021=GO_REF:0000029} Q9H3K2 Growth hormone-inducible transmembrane protein protein 20130415 {GO:0005515=IPI, GO:0008150=ND, GO:0003674=ND, GO:0005743=IEA, GO:0006915=IEA, GO:0016021=NAS} apoptotic process, biological_process integral to membrane, mitochondrial inner membrane molecular_function, protein binding Human UniProtKB:Q6PDS3 GHR BHF-UCL UniProtKB {GO:0005515=PMID:10502458, GO:0006549=GO_REF:0000024, GO:0019530=GO_REF:0000024, GO:0045597=GO_REF:0000019, GO:0050731=GO_REF:0000024, GO:0005615=PMID:2825030, GO:0042803=PMID:8137822, GO:0043025=GO_REF:0000019, GO:0004903=GO_REF:0000019, GO:0042169=GO_REF:0000019, GO:0070064=PMID:2825030, GO:0032869=GO_REF:0000019, GO:0019901=GO_REF:0000024, GO:0009986=PMID:8137822, GO:0019903=GO_REF:0000019, GO:1901215=GO_REF:0000019, GO:0043278=GO_REF:0000019, GO:0051384=GO_REF:0000019, GO:0046449=GO_REF:0000024, GO:0006897=GO_REF:0000037, GO:0043235=PMID:8137822, GO:0006600=GO_REF:0000024, GO:0005887=PMID:8137822, GO:0019898=GO_REF:0000019, GO:0042977=GO_REF:0000024, GO:0005886=Reactome:REACT_111235, GO:0000255=GO_REF:0000024, GO:0042523=PMID:2825030, GO:0060396=PMID:7565946, GO:0005634=GO_REF:0000019, GO:0060397=Reactome:REACT_111133, GO:0032094=GO_REF:0000019, GO:0032870=PMID:7565946, GO:0005739=GO_REF:0000019, GO:0000187=GO_REF:0000024, GO:0006101=GO_REF:0000024, GO:0006105=GO_REF:0000024, GO:0060351=GO_REF:0000019, GO:0040014=GO_REF:0000024, GO:0006103=GO_REF:0000024, GO:0006631=GO_REF:0000024, GO:0044236=PMID:8137822, GO:0070195=PMID:8137822, GO:0006573=GO_REF:0000024, GO:0040018=PMID:2813379, GO:0070555=GO_REF:0000019, GO:0042517=PMID:2825030, GO:0006107=GO_REF:0000024, GO:0005576=Reactome:REACT_111114, GO:0007259=GO_REF:0000024, GO:0009755=GO_REF:0000019, GO:0048009=PMID:7565946, GO:0016021=PMID:1549776, GO:0017046=PMID:2825030} P10912 Growth hormone receptor protein 20081207 {GO:0005515=IPI, GO:0006549=ISS, GO:0019530=ISS, GO:0045597=IEA, GO:0050731=ISS, GO:0005615=IMP, GO:0042803=IDA, GO:0043025=IEA, GO:0004903=IEA, GO:0042169=IEA, GO:0070064=ISS, GO:0032869=IEA, GO:0019901=ISS, GO:0009986=IDA, GO:0019903=IEA, GO:1901215=IEA, GO:0043278=IEA, GO:0051384=IEA, GO:0046449=ISS, GO:0006897=IEA, GO:0043235=IDA, GO:0006600=ISS, GO:0005887=IDA, GO:0019898=IEA, GO:0042977=ISS, GO:0005886=TAS, GO:0000255=ISS, GO:0042523=ISS, GO:0060396=IMP, GO:0005634=IEA, GO:0060397=TAS, GO:0032094=IEA, GO:0032870=IMP, GO:0005739=IEA, GO:0000187=ISS, GO:0006101=ISS, GO:0006105=ISS, GO:0060351=IEA, GO:0040014=ISS, GO:0006103=ISS, GO:0006631=ISS, GO:0044236=IMP, GO:0070195=IDA, GO:0006573=ISS, GO:0040018=IMP, GO:0070555=IEA, GO:0042517=ISS, GO:0006107=ISS, GO:0005576=TAS, GO:0007259=ISS, GO:0009755=IEA, GO:0048009=IMP, GO:0016021=IDA, GO:0017046=IPI} 2-oxoglutarate metabolic process, JAK-STAT cascade, JAK-STAT cascade involved in growth hormone signaling pathway, activation of JAK2 kinase activity, activation of MAPK activity, allantoin metabolic process, cartilage development involved in endochondral bone morphogenesis, cellular response to hormone stimulus, cellular response to insulin stimulus, citrate metabolic process, creatine metabolic process, creatinine metabolic process, endocytosis, fatty acid metabolic process, growth hormone receptor signaling pathway, hormone-mediated signaling pathway, insulin-like growth factor receptor signaling pathway, isoleucine metabolic process, multicellular organismal metabolic process, negative regulation of neuron death, oxaloacetate metabolic process, positive regulation of cell differentiation, positive regulation of multicellular organism growth, positive regulation of peptidyl-tyrosine phosphorylation, positive regulation of tyrosine phosphorylation of Stat3 protein, positive regulation of tyrosine phosphorylation of Stat5 protein, regulation of multicellular organism growth, response to food, response to glucocorticoid stimulus, response to interleukin-1, response to morphine, succinate metabolic process, taurine metabolic process, valine metabolic process cell surface, extracellular region, extracellular space, extrinsic to membrane, growth hormone receptor complex, integral to membrane, integral to plasma membrane, mitochondrion, neuronal cell body, nucleus, plasma membrane, receptor complex SH2 domain binding, growth hormone receptor activity, peptide hormone binding, proline-rich region binding, protein binding, protein homodimerization activity, protein kinase binding, protein phosphatase binding Human UniProtKB:P16882 GHRH BHF-UCL UniProtKB {GO:0021984=GO_REF:0000024, GO:0060124=PMID:11773624, GO:0008284=PMID:12867592, GO:0046005=PMID:15538933, GO:0030819=PMID:7680413, GO:0007267=PMID:6192430, GO:0005576=PMID:11773624, GO:0005615=GO_REF:0000024, GO:0032094=GO_REF:0000024, GO:0031770=PMID:7680413, GO:0043568=PMID:11773624, GO:0016608=PMID:18329818, GO:0043195=GO_REF:0000024, GO:0019933=PMID:7680413, GO:0030252=PMID:2857452, GO:0007189=PMID:1333056, GO:0040018=PMID:8421089} P01286 Somatoliberin protein 20081129 {GO:0021984=ISS, GO:0060124=NAS, GO:0008284=IDA, GO:0046005=IMP, GO:0030819=IDA, GO:0007267=TAS, GO:0005576=NAS, GO:0005615=ISS, GO:0032094=ISS, GO:0031770=IPI, GO:0043568=NAS, GO:0016608=IDA, GO:0043195=ISS, GO:0019933=IDA, GO:0030252=IDA, GO:0007189=IC, GO:0040018=IMP} adenohypophysis development, adenylate cyclase-activating G-protein coupled receptor signaling pathway, cAMP-mediated signaling, cell-cell signaling, growth hormone secretion, positive regulation of cAMP biosynthetic process, positive regulation of cell proliferation, positive regulation of circadian sleep/wake cycle, REM sleep, positive regulation of growth hormone secretion, positive regulation of insulin-like growth factor receptor signaling pathway, positive regulation of multicellular organism growth, response to food extracellular region, extracellular space, terminal bouton growth hormone-releasing hormone activity, growth hormone-releasing hormone receptor binding Human GHRHR UniProtKB UniProtKB {GO:0005515=PMID:7680413, GO:0060124=PMID:11773624, GO:0008284=PMID:12867592, GO:0043627=PMID:9482665, GO:0005886=GO_REF:0000040, GO:0030819=PMID:7680413, GO:0005637=PMID:10461027, GO:0033143=GO_REF:0000019, GO:0016520=PMID:10962031, GO:0008340=GO_REF:0000019, GO:0016363=PMID:10461027, GO:0005640=PMID:10461027, GO:0048609=PMID:15944917, GO:0030104=GO_REF:0000019, GO:0007190=GO_REF:0000019, GO:0005737=PMID:10461027, GO:0019838=PMID:7680413, GO:0030252=GO_REF:0000019, GO:0048469=GO_REF:0000019, GO:0040018=PMID:8528260, GO:0030141=PMID:10461027, GO:0032868=PMID:17356054, GO:0051246=GO_REF:0000019, GO:0032869=GO_REF:0000019, GO:0009986=PMID:1333056, GO:0004930=PMID:1333056, GO:0060133=GO_REF:0000019, GO:0051384=PMID:9482665, GO:0008150=GO_REF:0000015, GO:0007186=GO_REF:0000029, GO:0007595=GO_REF:0000019, GO:0043568=PMID:11773624, GO:0019933=PMID:7680413, GO:0042445=GO_REF:0000019, GO:0007189=PMID:1333056, GO:0016021=PMID:10962031, GO:0017046=PMID:7680413} Q9HB45 Growth hormone-releasing hormone receptor protein 20021106 {GO:0005515=IPI, GO:0060124=NAS, GO:0008284=IDA, GO:0043627=IDA, GO:0005886=IEA, GO:0030819=IDA, GO:0005637=IDA, GO:0033143=IEA, GO:0016520=NAS, GO:0008340=IEA, GO:0016363=IDA, GO:0005640=IDA, GO:0048609=NAS, GO:0030104=IEA, GO:0007190=IEA, GO:0005737=IDA, GO:0019838=IPI, GO:0030252=IEA, GO:0048469=IEA, GO:0040018=IMP, GO:0030141=IDA, GO:0032868=IMP, GO:0051246=IEA, GO:0032869=IEA, GO:0009986=IDA, GO:0004930=IC, GO:0060133=IEA, GO:0051384=IDA, GO:0008150=ND, GO:0007186=NAS, GO:0007595=IEA, GO:0043568=NAS, GO:0019933=IMP, GO:0042445=IEA, GO:0007189=IDA, GO:0016021=NAS, GO:0017046=IPI} G-protein coupled receptor signaling pathway, activation of adenylate cyclase activity, adenylate cyclase-activating G-protein coupled receptor signaling pathway, biological_process, cAMP-mediated signaling, cell maturation, cellular response to insulin stimulus, determination of adult lifespan, growth hormone secretion, hormone metabolic process, lactation, multicellular organismal reproductive process, positive regulation of cAMP biosynthetic process, positive regulation of cell proliferation, positive regulation of growth hormone secretion, positive regulation of insulin-like growth factor receptor signaling pathway, positive regulation of multicellular organism growth, regulation of intracellular steroid hormone receptor signaling pathway, regulation of protein metabolic process, response to estrogen stimulus, response to glucocorticoid stimulus, response to insulin stimulus, somatotropin secreting cell development, water homeostasis cell surface, cytoplasm, integral to membrane, nuclear inner membrane, nuclear matrix, nuclear outer membrane, plasma membrane, secretory granule G-protein coupled receptor activity, growth factor binding, growth hormone-releasing hormone receptor activity, peptide hormone binding, protein binding Human GHRL GOC UniProtKB {GO:0008343=GO_REF:0000024, GO:0060124=PMID:18329818, GO:0030424=PMID:17113048, GO:0043627=PMID:15292338, GO:0051216=PMID:15576457, GO:0061098=PMID:15350694, GO:0032691=PMID:15232612, GO:0032100=GO_REF:0000024, GO:0060399=PMID:12566947, GO:0045409=PMID:15232612, GO:0007204=GO_REF:0000024, GO:0001696=GO_REF:0000019, GO:0005615=PMID:15039149, GO:0000187=PMID:15350694, GO:0046697=PMID:17494105, GO:0005737=GO_REF:0000019, GO:0030296=PMID:15350694, GO:0040013=GO_REF:0000019, GO:0042127=PMID:16394173, GO:0006006=PMID:17392603, GO:0051461=PMID:12566947, GO:0030252=PMID:16511605, GO:0032024=GO_REF:0000024, GO:0031768=PMID:16511605, GO:0009725=PMID:15232612, GO:0040018=PMID:16511605, GO:0046676=GO_REF:0000019, GO:0046010=PMID:18329818, GO:0051464=PMID:18329818, GO:0043400=PMID:17201814, GO:0051965=PMID:16491079, GO:0043066=PMID:15158140, GO:0001664=PMID:10604470, GO:0042536=PMID:15232612, GO:0060079=GO_REF:0000019, GO:0005576=Reactome:REACT_22436, GO:0016358=PMID:16491079, GO:0009755=PMID:16511605, GO:0042322=PMID:18329818, GO:0007186=PMID:16511605, GO:0016608=PMID:16511605, GO:0001937=PMID:15572208, GO:0008154=PMID:15232612, GO:0050728=PMID:15232612, GO:0016525=PMID:15572208, GO:0005788=Reactome:REACT_19329, GO:0044267=Reactome:REACT_17015, GO:0034774=Reactome:REACT_19170} Q9UBU3 Appetite-regulating hormone protein 20130413 {GO:0008343=ISS, GO:0060124=IDA, GO:0030424=IDA, GO:0043627=IDA, GO:0051216=NAS, GO:0061098=IMP, GO:0032691=IDA, GO:0032100=ISS, GO:0060399=IC, GO:0045409=IDA, GO:0007204=ISS, GO:0001696=IEA, GO:0005615=IDA, GO:0000187=IMP, GO:0046697=IDA, GO:0005737=IEA, GO:0030296=IMP, GO:0040013=IEA, GO:0042127=IDA, GO:0006006=NAS, GO:0051461=IDA, GO:0030252=TAS, GO:0032024=ISS, GO:0031768=TAS, GO:0009725=IDA, GO:0040018=IC, GO:0046676=IEA, GO:0046010=IDA, GO:0051464=IDA, GO:0043400=NAS, GO:0051965=IDA, GO:0043066=IDA, GO:0001664=ISS, GO:0042536=IDA, GO:0060079=IEA, GO:0005576=TAS, GO:0016358=IDA, GO:0009755=TAS, GO:0042322=IDA, GO:0007186=TAS, GO:0016608=TAS, GO:0001937=IDA, GO:0008154=IDA, GO:0050728=IDA, GO:0016525=NAS, GO:0005788=TAS, GO:0044267=TAS, GO:0034774=TAS} G-protein coupled receptor signaling pathway, actin polymerization or depolymerization, activation of MAPK activity, adult feeding behavior, cartilage development, cellular protein metabolic process, cortisol secretion, decidualization, dendrite development, elevation of cytosolic calcium ion concentration, gastric acid secretion, glucose metabolic process, growth hormone secretion, hormone-mediated signaling pathway, negative regulation of angiogenesis, negative regulation of apoptotic process, negative regulation of circadian sleep/wake cycle, REM sleep, negative regulation of endothelial cell proliferation, negative regulation of inflammatory response, negative regulation of insulin secretion, negative regulation of interleukin-1 beta production, negative regulation of interleukin-6 biosynthetic process, negative regulation of locomotion, negative regulation of tumor necrosis factor biosynthetic process, positive regulation of appetite, positive regulation of circadian sleep/wake cycle, non-REM sleep, positive regulation of corticotropin secretion, positive regulation of cortisol secretion, positive regulation of growth hormone receptor signaling pathway, positive regulation of growth hormone secretion, positive regulation of insulin secretion, positive regulation of multicellular organism growth, positive regulation of protein tyrosine kinase activity, positive regulation of synapse assembly, regulation of cell proliferation, regulation of excitatory postsynaptic membrane potential, response to estrogen stimulus, response to hormone stimulus axon, cytoplasm, endoplasmic reticulum lumen, extracellular region, extracellular space, secretory granule lumen G-protein coupled receptor binding, ghrelin receptor binding, growth hormone-releasing hormone activity, protein tyrosine kinase activator activity Human GHSR Reactome UniProtKB {GO:0008343=GO_REF:0000024, GO:0043005=PMID:12890514, GO:0005886=Reactome:REACT_22436, GO:0032691=PMID:15232612, GO:0032100=GO_REF:0000024, GO:0045409=PMID:15232612, GO:0016520=PMID:8688086, GO:0032094=GO_REF:0000019, GO:0046697=PMID:17494105, GO:0045923=GO_REF:0000019, GO:0001616=PMID:8688086, GO:0030252=PMID:16511605, GO:0009725=PMID:15232612, GO:0040018=PMID:16511605, GO:0046676=GO_REF:0000019, GO:0051963=GO_REF:0000019, GO:0032869=GO_REF:0000019, GO:0009986=PMID:8688086, GO:0004930=PMID:8688086, GO:0042536=PMID:15232612, GO:0009755=PMID:8688086, GO:0007186=PMID:8688086, GO:0008154=PMID:15232612, GO:0043568=GO_REF:0000019, GO:0050728=PMID:15232612, GO:0045121=PMID:15232612, GO:0016021=GO_REF:0000037, GO:0017046=GO_REF:0000019, GO:0043134=GO_REF:0000019} Q92847 Growth hormone secretagogue receptor type 1 protein 20101028 {GO:0008343=ISS, GO:0043005=IDA, GO:0005886=TAS, GO:0032691=IDA, GO:0032100=ISS, GO:0045409=IDA, GO:0016520=IDA, GO:0032094=IEA, GO:0046697=IDA, GO:0045923=IEA, GO:0001616=IDA, GO:0030252=TAS, GO:0009725=IDA, GO:0040018=IMP, GO:0046676=IEA, GO:0051963=IEA, GO:0032869=IEA, GO:0009986=IDA, GO:0004930=IDA, GO:0042536=IDA, GO:0009755=IDA, GO:0007186=IDA, GO:0008154=IDA, GO:0043568=IEA, GO:0050728=IDA, GO:0045121=IDA, GO:0016021=IEA, GO:0017046=IEA, GO:0043134=IEA} G-protein coupled receptor signaling pathway, actin polymerization or depolymerization, adult feeding behavior, cellular response to insulin stimulus, decidualization, growth hormone secretion, hormone-mediated signaling pathway, negative regulation of inflammatory response, negative regulation of insulin secretion, negative regulation of interleukin-1 beta production, negative regulation of interleukin-6 biosynthetic process, negative regulation of tumor necrosis factor biosynthetic process, positive regulation of appetite, positive regulation of fatty acid metabolic process, positive regulation of insulin-like growth factor receptor signaling pathway, positive regulation of multicellular organism growth, regulation of hindgut contraction, regulation of synapse assembly, response to food, response to hormone stimulus cell surface, integral to membrane, membrane raft, neuron projection, plasma membrane G-protein coupled receptor activity, growth hormone secretagogue receptor activity, growth hormone-releasing hormone receptor activity, peptide hormone binding Human GIF UniProtKB UniProtKB {GO:0005902=PMID:8886952, GO:0016324=PMID:8886952, GO:0015889=PMID:15738392, GO:0009235=GO_REF:0000033, GO:0031419=PMID:14695536, GO:0005615=PMID:14695536, GO:0005768=PMID:8886952, GO:0006824=GO_REF:0000037} P27352 Gastric intrinsic factor protein 20090814 {GO:0005902=IDA, GO:0016324=IDA, GO:0015889=IMP, GO:0009235=IBA, GO:0031419=IDA, GO:0005615=IDA, GO:0005768=IDA, GO:0006824=IEA} cobalamin metabolic process, cobalamin transport, cobalt ion transport apical plasma membrane, endosome, extracellular space, microvillus cobalamin binding Human GIGYF1 ENSEMBL UniProtKB {GO:0048009=GO_REF:0000019} O75420 PERQ amino acid-rich with GYF domain-containing protein 1 protein 20130413 {GO:0048009=IEA} insulin-like growth factor receptor signaling pathway Human Ensembl:ENSMUSP00000031727 GIGYF2 MGI UniProtKB {GO:0017148=PMID:22751931, GO:0007631=GO_REF:0000019, GO:0008344=GO_REF:0000019, GO:0008219=GO_REF:0000037, GO:0021522=GO_REF:0000019, GO:0009791=GO_REF:0000019, GO:0000084=GO_REF:0000019, GO:0048873=GO_REF:0000019, GO:0035264=GO_REF:0000019, GO:0050881=GO_REF:0000019, GO:0050885=GO_REF:0000019, GO:0048009=GO_REF:0000019, GO:0044267=GO_REF:0000019} Q6Y7W6 PERQ amino acid-rich with GYF domain-containing protein 2 protein 20130211 {GO:0017148=IMP, GO:0007631=IEA, GO:0008344=IEA, GO:0008219=IEA, GO:0021522=IEA, GO:0009791=IEA, GO:0000084=IEA, GO:0048873=IEA, GO:0035264=IEA, GO:0050881=IEA, GO:0050885=IEA, GO:0048009=IEA, GO:0044267=IEA} S phase of mitotic cell cycle, adult locomotory behavior, cell death, cellular protein metabolic process, feeding behavior, homeostasis of number of cells within a tissue, insulin-like growth factor receptor signaling pathway, multicellular organism growth, musculoskeletal movement, negative regulation of translation, neuromuscular process controlling balance, post-embryonic development, spinal cord motor neuron differentiation Human GIMAP1 UniProtKB UniProtKB {GO:0000139=GO_REF:0000039, GO:0030217=GO_REF:0000019, GO:0030183=GO_REF:0000019, GO:0005789=GO_REF:0000039, GO:0016021=GO_REF:0000037, GO:0005525=GO_REF:0000019} Q8WWP7 GTPase IMAP family member 1 protein 20130413 {GO:0000139=IEA, GO:0030217=IEA, GO:0030183=IEA, GO:0005789=IEA, GO:0016021=IEA, GO:0005525=IEA} B cell differentiation, T cell differentiation Golgi membrane, endoplasmic reticulum membrane, integral to membrane GTP binding Human UniProtKB-SubCell:SL-0097 GIMAP4 HPA UniProtKB {GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0005525=GO_REF:0000037, GO:0005829=GO_REF:0000039} Q9NUV9 GTPase IMAP family member 4 protein 20111111 {GO:0005730=IDA, GO:0005634=IDA, GO:0005525=IEA, GO:0005829=IEA} cytosol, nucleolus, nucleus GTP binding NOT Human GIMAP5 UniProtKB UniProtKB {GO:0046902=GO_REF:0000019, GO:0032831=GO_REF:0000019, GO:0043066=GO_REF:0000019, GO:0050995=GO_REF:0000019, GO:0001659=GO_REF:0000019, GO:0050868=GO_REF:0000019, GO:0002729=GO_REF:0000019, GO:0010524=GO_REF:0000019, GO:0045588=GO_REF:0000019, GO:0005741=GO_REF:0000039, GO:0005525=GO_REF:0000037, GO:0005764=GO_REF:0000039, GO:0045838=GO_REF:0000019, GO:0002925=GO_REF:0000019, GO:0030217=GO_REF:0000019, GO:0045019=GO_REF:0000019, GO:0045954=GO_REF:0000019, GO:0016021=GO_REF:0000037, GO:0043011=GO_REF:0000019, GO:0043029=GO_REF:0000019, GO:0032689=GO_REF:0000019} Q96F15 GTPase IMAP family member 5 protein 20130413 {GO:0046902=IEA, GO:0032831=IEA, GO:0043066=IEA, GO:0050995=IEA, GO:0001659=IEA, GO:0050868=IEA, GO:0002729=IEA, GO:0010524=IEA, GO:0045588=IEA, GO:0005741=IEA, GO:0005525=IEA, GO:0005764=IEA, GO:0045838=IEA, GO:0002925=IEA, GO:0030217=IEA, GO:0045019=IEA, GO:0045954=IEA, GO:0016021=IEA, GO:0043011=IEA, GO:0043029=IEA, GO:0032689=IEA} T cell differentiation, T cell homeostasis, myeloid dendritic cell differentiation, negative regulation of T cell activation, negative regulation of apoptotic process, negative regulation of interferon-gamma production, negative regulation of lipid catabolic process, negative regulation of nitric oxide biosynthetic process, positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation, positive regulation of calcium ion transport into cytosol, positive regulation of gamma-delta T cell differentiation, positive regulation of humoral immune response mediated by circulating immunoglobulin, positive regulation of membrane potential, positive regulation of natural killer cell cytokine production, positive regulation of natural killer cell mediated cytotoxicity, regulation of mitochondrial membrane permeability, temperature homeostasis integral to membrane, lysosome, mitochondrial outer membrane GTP binding Human UniProtKB-SubCell:SL-0158 GIMAP6 UniProtKB UniProtKB {GO:0005525=GO_REF:0000037} Q6P9H5 GTPase IMAP family member 6 protein 20130413 {GO:0005525=IEA} GTP binding Human UniProtKB-KW:KW-0342 GIMAP7 UniProtKB UniProtKB {GO:0005525=GO_REF:0000037} Q8NHV1 GTPase IMAP family member 7 protein 20130413 {GO:0005525=IEA} GTP binding Human UniProtKB-KW:KW-0342 GIMAP8 HPA UniProtKB {GO:0005739=GO_REF:0000039, GO:0005737=GO_REF:0000052, GO:0005794=GO_REF:0000039, GO:0005783=GO_REF:0000039, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0005525=GO_REF:0000037} Q8ND71 GTPase IMAP family member 8 protein 20090616 {GO:0005739=IEA, GO:0005737=IDA, GO:0005794=IEA, GO:0005783=IEA, GO:0005730=IDA, GO:0005634=IDA, GO:0005525=IEA} Golgi apparatus, cytoplasm, endoplasmic reticulum, mitochondrion, nucleolus, nucleus GTP binding Human GIN1 InterPro UniProtKB {GO:0015074=GO_REF:0000002, GO:0003676=GO_REF:0000002} Q9NXP7 Gypsy retrotransposon integrase-like protein 1 protein 20130413 {GO:0015074=IEA, GO:0003676=IEA} DNA integration nucleic acid binding Human InterPro:IPR001584 GINS1 Reactome UniProtKB {GO:0000084=Reactome:REACT_899, GO:0006271=Reactome:REACT_932, GO:0005737=PMID:10942595, GO:0001833=GO_REF:0000019, GO:0005654=Reactome:REACT_6747, GO:0005634=PMID:10942595, GO:0000278=Reactome:REACT_152} Q14691 DNA replication complex GINS protein PSF1 protein 20130213 {GO:0000084=TAS, GO:0006271=TAS, GO:0005737=IDA, GO:0001833=IEA, GO:0005654=TAS, GO:0005634=IDA, GO:0000278=TAS} DNA strand elongation involved in DNA replication, S phase of mitotic cell cycle, inner cell mass cell proliferation, mitotic cell cycle cytoplasm, nucleoplasm, nucleus Human GINS2 IntAct UniProtKB {GO:0005515=PMID:17525332, GO:0000084=Reactome:REACT_899, GO:0006260=GO_REF:0000002, GO:0006271=Reactome:REACT_932, GO:0005654=Reactome:REACT_6747, GO:0005634=GO_REF:0000002, GO:0000278=Reactome:REACT_152} Q9Y248 DNA replication complex GINS protein PSF2 protein 20130415 {GO:0005515=IPI, GO:0000084=TAS, GO:0006260=IEA, GO:0006271=TAS, GO:0005654=TAS, GO:0005634=IEA, GO:0000278=TAS} DNA replication, DNA strand elongation involved in DNA replication, S phase of mitotic cell cycle, mitotic cell cycle nucleoplasm, nucleus protein binding Human UniProtKB:O96017 GINS3 UniProtKB UniProtKB {GO:0006260=GO_REF:0000037, GO:0005634=GO_REF:0000039} Q9BRX5 DNA replication complex GINS protein PSF3 protein 20130413 {GO:0006260=IEA, GO:0005634=IEA} DNA replication nucleus Human UniProtKB-SubCell:SL-0191 GINS4 Reactome UniProtKB {GO:0000084=Reactome:REACT_899, GO:0006260=GO_REF:0000038, GO:0006271=Reactome:REACT_932, GO:0005737=GO_REF:0000039, GO:0005654=Reactome:REACT_6747, GO:0005634=GO_REF:0000019, GO:0000278=Reactome:REACT_152} Q9BRT9 DNA replication complex GINS protein SLD5 protein 20130213 {GO:0000084=TAS, GO:0006260=IEA, GO:0006271=TAS, GO:0005737=IEA, GO:0005654=TAS, GO:0005634=IEA, GO:0000278=TAS} DNA replication, DNA strand elongation involved in DNA replication, S phase of mitotic cell cycle, mitotic cell cycle cytoplasm, nucleoplasm, nucleus Human GIP Reactome UniProtKB {GO:0055123=GO_REF:0000019, GO:0014070=GO_REF:0000019, GO:0008344=GO_REF:0000019, GO:0043434=GO_REF:0000019, GO:0070328=GO_REF:0000019, GO:0060291=GO_REF:0000019, GO:0048678=GO_REF:0000019, GO:0042594=GO_REF:0000019, GO:0043025=GO_REF:0000019, GO:0043950=GO_REF:0000019, GO:0032024=GO_REF:0000019, GO:0007613=GO_REF:0000019, GO:0043200=GO_REF:0000019, GO:0035640=GO_REF:0000019, GO:0007565=GO_REF:0000019, GO:0042493=GO_REF:0000019, GO:0070094=GO_REF:0000019, GO:0010269=GO_REF:0000019, GO:0005576=Reactome:REACT_23981, GO:0019233=GO_REF:0000019, GO:0010828=GO_REF:0000019, GO:0009749=GO_REF:0000019, GO:0007165=PMID:2890159, GO:0050796=Reactome:REACT_23974, GO:0005179=GO_REF:0000037, GO:0031018=GO_REF:0000019, GO:0005788=Reactome:REACT_23843, GO:0044267=Reactome:REACT_17015, GO:0034774=Reactome:REACT_23868} P09681 Gastric inhibitory polypeptide protein 20130228 {GO:0055123=IEA, GO:0014070=IEA, GO:0008344=IEA, GO:0043434=IEA, GO:0070328=IEA, GO:0060291=IEA, GO:0048678=IEA, GO:0042594=IEA, GO:0043025=IEA, GO:0043950=IEA, GO:0032024=IEA, GO:0007613=IEA, GO:0043200=IEA, GO:0035640=IEA, GO:0007565=IEA, GO:0042493=IEA, GO:0070094=IEA, GO:0010269=IEA, GO:0005576=TAS, GO:0019233=IEA, GO:0010828=IEA, GO:0009749=IEA, GO:0007165=TAS, GO:0050796=TAS, GO:0005179=IEA, GO:0031018=IEA, GO:0005788=TAS, GO:0044267=TAS, GO:0034774=TAS} adult locomotory behavior, cellular protein metabolic process, digestive system development, endocrine pancreas development, exploration behavior, female pregnancy, long-term synaptic potentiation, memory, positive regulation of cAMP-mediated signaling, positive regulation of glucagon secretion, positive regulation of glucose transport, positive regulation of insulin secretion, regulation of insulin secretion, response to amino acid stimulus, response to axon injury, response to drug, response to glucose stimulus, response to organic cyclic compound, response to peptide hormone stimulus, response to selenium ion, response to starvation, sensory perception of pain, signal transduction, triglyceride homeostasis endoplasmic reticulum lumen, extracellular region, neuronal cell body, secretory granule lumen hormone activity Human GIPC1 BHF-UCL UniProtKB {GO:0005515=PMID:9770488, GO:0007268=GO_REF:0000024, GO:0030139=GO_REF:0000019, GO:0032435=GO_REF:0000024, GO:0006605=GO_REF:0000024, GO:0042803=GO_REF:0000024, GO:0005829=GO_REF:0000024, GO:0005737=GO_REF:0000024, GO:0031647=GO_REF:0000024, GO:0043197=GO_REF:0000024, GO:0043198=GO_REF:0000024, GO:0048167=GO_REF:0000024, GO:0005938=PMID:12857860, GO:0030511=GO_REF:0000024, GO:0012506=GO_REF:0000024, GO:0005102=PMID:15459234, GO:0003779=GO_REF:0000024, GO:0030165=GO_REF:0000019, GO:0014047=GO_REF:0000024, GO:0008021=GO_REF:0000024, GO:0044445=GO_REF:0000019, GO:0005903=GO_REF:0000019, GO:0016020=GO_REF:0000024, GO:0007186=PMID:9770488, GO:0043542=GO_REF:0000024, GO:0016023=PMID:12857860, GO:0017022=GO_REF:0000024} O14908 PDZ domain-containing protein GIPC1 protein 20080820 {GO:0005515=IPI, GO:0007268=ISS, GO:0030139=IEA, GO:0032435=ISS, GO:0006605=ISS, GO:0042803=ISS, GO:0005829=ISS, GO:0005737=ISS, GO:0031647=ISS, GO:0043197=ISS, GO:0043198=ISS, GO:0048167=ISS, GO:0005938=IDA, GO:0030511=ISS, GO:0012506=ISS, GO:0005102=IPI, GO:0003779=ISS, GO:0030165=IEA, GO:0014047=ISS, GO:0008021=ISS, GO:0044445=IEA, GO:0005903=IEA, GO:0016020=ISS, GO:0007186=NAS, GO:0043542=ISS, GO:0016023=IDA, GO:0017022=ISS} G-protein coupled receptor signaling pathway, endothelial cell migration, glutamate secretion, negative regulation of proteasomal ubiquitin-dependent protein catabolic process, positive regulation of transforming growth factor beta receptor signaling pathway, protein targeting, regulation of protein stability, regulation of synaptic plasticity, synaptic transmission brush border, cell cortex, cytoplasm, cytoplasmic membrane-bounded vesicle, cytosol, cytosolic part, dendritic shaft, dendritic spine, endocytic vesicle, membrane, synaptic vesicle, vesicle membrane PDZ domain binding, actin binding, myosin binding, protein binding, protein homodimerization activity, receptor binding Human UniProtKB:Q9Z0G0 GIPC2 UniProtKB UniProtKB {GO:0005737=GO_REF:0000039} Q8TF65 PDZ domain-containing protein GIPC2 protein 20130413 {GO:0005737=IEA} cytoplasm Human UniProtKB-SubCell:SL-0086 GIPC3 null null {} null null null null {} null null null GIPR Reactome UniProtKB {GO:0007190=PMID:7589426, GO:0016519=GO_REF:0000002, GO:0005886=Reactome:REACT_22268, GO:0007584=PMID:7556958, GO:0006091=PMID:7556958, GO:0016021=GO_REF:0000037, GO:0007166=PMID:7556958, GO:0004888=PMID:7556958} P48546 Gastric inhibitory polypeptide receptor protein 20090511 {GO:0007190=TAS, GO:0016519=IEA, GO:0005886=TAS, GO:0007584=TAS, GO:0006091=TAS, GO:0016021=IEA, GO:0007166=TAS, GO:0004888=TAS} activation of adenylate cyclase activity, cell surface receptor signaling pathway, generation of precursor metabolites and energy, response to nutrient integral to membrane, plasma membrane gastric inhibitory peptide receptor activity, transmembrane signaling receptor activity Human GIT1 HPA UniProtKB {GO:0005515=PMID:21295525, GO:0008060=GO_REF:0000002, GO:0005737=GO_REF:0000052, GO:0008277=PMID:9826657, GO:0032312=GO_REF:0000002, GO:0008270=GO_REF:0000002, GO:0005925=GO_REF:0000052} Q9Y2X7 ARF GTPase-activating protein GIT1 protein 20101115 {GO:0005515=IPI, GO:0008060=IEA, GO:0005737=IDA, GO:0008277=TAS, GO:0032312=IEA, GO:0008270=IEA, GO:0005925=IDA} regulation of ARF GTPase activity, regulation of G-protein coupled receptor protein signaling pathway cytoplasm, focal adhesion ARF GTPase activator activity, protein binding, zinc ion binding Human GIT2 IntAct UniProtKB {GO:0005515=PMID:21988832, GO:0008060=GO_REF:0000002, GO:0008277=PMID:10896954, GO:0032312=GO_REF:0000002, GO:0005654=PMID:10942595, GO:0008270=GO_REF:0000002} Q14161 ARF GTPase-activating protein GIT2 protein 20130415 {GO:0005515=IPI, GO:0008060=IEA, GO:0008277=TAS, GO:0032312=IEA, GO:0005654=IDA, GO:0008270=IEA} regulation of ARF GTPase activity, regulation of G-protein coupled receptor protein signaling pathway nucleoplasm ARF GTPase activator activity, protein binding, zinc ion binding Human UniProtKB:Q9Y6K9 GJA1 GOC UniProtKB {GO:0005515=PMID:15709751, GO:0017124=GO_REF:0000019, GO:0045732=GO_REF:0000019, GO:0008285=GO_REF:0000019, GO:2000810=GO_REF:0000019, GO:0005886=GO_REF:0000024, GO:0015075=PMID:1696265, GO:0007267=PMID:7715640, GO:0043434=GO_REF:0000019, GO:0005741=GO_REF:0000019, GO:0010232=GO_REF:0000019, GO:0016264=Reactome:REACT_9509, GO:0005764=GO_REF:0000019, GO:0051259=GO_REF:0000019, GO:0005916=GO_REF:0000019, GO:0007507=GO_REF:0000002, GO:0034220=PMID:1696265, GO:0006936=PMID:7715640, GO:0014704=GO_REF:0000024, GO:0051924=GO_REF:0000019, GO:0006810=PMID:1696265, GO:0004871=PMID:12761501, GO:0043123=PMID:12761501, GO:0010644=PMID:16790700, GO:0009268=GO_REF:0000019, GO:0005243=PMID:23348765, GO:0005794=GO_REF:0000024, GO:0005771=GO_REF:0000019, GO:0006915=GO_REF:0000019, GO:0030165=GO_REF:0000019, GO:0007165=PMID:12761501, GO:0000139=Reactome:REACT_10110, GO:0005887=PMID:15709751, GO:0030660=Reactome:REACT_10110, GO:0048812=GO_REF:0000019, GO:0005789=Reactome:REACT_9473, GO:0086014=PMID:23348765, GO:0005921=PMID:23348765, GO:0015867=GO_REF:0000019, GO:0045121=GO_REF:0000024, GO:0005922=GO_REF:0000002, GO:0016044=Reactome:REACT_11123, GO:0005769=GO_REF:0000019} P17302 Gap junction alpha-1 protein protein 20130413 {GO:0005515=IPI, GO:0017124=IEA, GO:0045732=IEA, GO:0008285=IEA, GO:2000810=IEA, GO:0005886=ISS, GO:0015075=TAS, GO:0007267=TAS, GO:0043434=IEA, GO:0005741=IEA, GO:0010232=IEA, GO:0016264=TAS, GO:0005764=IEA, GO:0051259=IEA, GO:0005916=IEA, GO:0007507=IEA, GO:0034220=TAS, GO:0006936=TAS, GO:0014704=ISS, GO:0051924=IEA, GO:0006810=TAS, GO:0004871=IMP, GO:0043123=IMP, GO:0010644=IDA, GO:0009268=IEA, GO:0005243=IDA, GO:0005794=ISS, GO:0005771=IEA, GO:0006915=IEA, GO:0030165=IEA, GO:0007165=IMP, GO:0000139=TAS, GO:0005887=TAS, GO:0030660=TAS, GO:0048812=IEA, GO:0005789=TAS, GO:0086014=TAS, GO:0005921=IDA, GO:0015867=IEA, GO:0045121=ISS, GO:0005922=IEA, GO:0016044=TAS, GO:0005769=IEA} ATP transport, apoptotic process, cell communication by electrical coupling, cell-cell signaling, cellular membrane organization, gap junction assembly, heart development, ion transmembrane transport, muscle contraction, negative regulation of cell proliferation, neuron projection morphogenesis, positive regulation of I-kappaB kinase/NF-kappaB cascade, positive regulation of protein catabolic process, protein oligomerization, regulation of atrial cardiac muscle cell action potential, regulation of calcium ion transport, regulation of tight junction assembly, response to pH, response to peptide hormone stimulus, signal transduction, transport, vascular transport Golgi apparatus, Golgi membrane, Golgi-associated vesicle membrane, connexon complex, early endosome, endoplasmic reticulum membrane, fascia adherens, gap junction, integral to plasma membrane, intercalated disc, lysosome, membrane raft, mitochondrial outer membrane, multivesicular body, plasma membrane PDZ domain binding, SH3 domain binding, gap junction channel activity, ion transmembrane transporter activity, protein binding, signal transducer activity Human GJA10 Reactome UniProtKB {GO:0005243=Reactome:REACT_17030, GO:0005886=Reactome:REACT_17030, GO:0050908=GO_REF:0000019, GO:0007276=GO_REF:0000019, GO:0007268=Reactome:REACT_13685, GO:0005922=GO_REF:0000002, GO:0016021=GO_REF:0000037, GO:0007416=GO_REF:0000019} Q969M2 Gap junction alpha-10 protein protein 20130213 {GO:0005243=TAS, GO:0005886=TAS, GO:0050908=IEA, GO:0007276=IEA, GO:0007268=TAS, GO:0005922=IEA, GO:0016021=IEA, GO:0007416=IEA} detection of light stimulus involved in visual perception, gamete generation, synapse assembly, synaptic transmission connexon complex, integral to membrane, plasma membrane gap junction channel activity Human GJA3 PINC UniProtKB {GO:0005243=GO_REF:0000002, GO:0007267=PMID:9413992, GO:0006810=PMID:9413992, GO:0005922=GO_REF:0000002, GO:0016021=GO_REF:0000037, GO:0007601=PMID:10205266} Q9Y6H8 Gap junction alpha-3 protein protein 20030904 {GO:0005243=IEA, GO:0007267=TAS, GO:0006810=NAS, GO:0005922=IEA, GO:0016021=IEA, GO:0007601=TAS} cell-cell signaling, transport, visual perception connexon complex, integral to membrane gap junction channel activity Human GJA4 ENSEMBL UniProtKB {GO:0001568=GO_REF:0000019, GO:0005887=PMID:7680674, GO:0007043=PMID:7680674, GO:0006810=PMID:7680674, GO:0007267=GO_REF:0000019, GO:0005921=PMID:7680674, GO:0048265=GO_REF:0000019, GO:0006816=GO_REF:0000019, GO:0005922=GO_REF:0000019, GO:0016021=GO_REF:0000038} Q5JW71 Gap junction alpha-4 protein protein 20130413 {GO:0001568=IEA, GO:0005887=TAS, GO:0007043=TAS, GO:0006810=TAS, GO:0007267=IEA, GO:0005921=TAS, GO:0048265=IEA, GO:0006816=IEA, GO:0005922=IEA, GO:0016021=IEA} blood vessel development, calcium ion transport, cell-cell junction assembly, cell-cell signaling, response to pain, transport connexon complex, gap junction, integral to membrane, integral to plasma membrane Human Ensembl:ENSRNOP00000019246 GJA5 BHF-UCL UniProtKB {GO:0035922=GO_REF:0000019, GO:0003161=GO_REF:0000019, GO:0086053=PMID:22247482, GO:0003283=PMID:22199024, GO:0003284=GO_REF:0000019, GO:0048844=GO_REF:0000024, GO:0055077=PMID:23348765, GO:0003281=PMID:22199024, GO:0060307=GO_REF:0000019, GO:0030326=GO_REF:0000019, GO:0016264=PMID:22247482, GO:0086091=GO_REF:0000019, GO:0086075=PMID:16790700, GO:1900825=GO_REF:0000019, GO:0060371=PMID:23348765, GO:0042312=GO_REF:0000019, GO:0060373=GO_REF:0000019, GO:0086069=PMID:22247482, GO:0014704=PMID:23348765, GO:0086005=GO_REF:0000019, GO:0003294=GO_REF:0000019, GO:0035050=GO_REF:0000019, GO:0060413=GO_REF:0000019, GO:0060412=GO_REF:0000019, GO:0003193=PMID:22199024, GO:0003174=PMID:22199024, GO:0001525=PMID:11866539, GO:0086064=PMID:16790700, GO:0003151=PMID:22199024, GO:0003071=GO_REF:0000019, GO:0001501=GO_REF:0000019, GO:1900133=GO_REF:0000019, GO:0005887=PMID:22247482, GO:0086077=PMID:22247482, GO:0055117=PMID:16790700, GO:0086014=PMID:23348765, GO:0005921=PMID:23348765, GO:0005922=PMID:22247482, GO:0086015=GO_REF:0000019} P36382 Gap junction alpha-5 protein protein 20130130 {GO:0035922=IEA, GO:0003161=IEA, GO:0086053=IMP, GO:0003283=IMP, GO:0003284=IEA, GO:0048844=ISS, GO:0055077=IDA, GO:0003281=IMP, GO:0060307=IEA, GO:0030326=IEA, GO:0016264=IDA, GO:0086091=IEA, GO:0086075=IMP, GO:1900825=IEA, GO:0060371=IMP, GO:0042312=IEA, GO:0060373=IEA, GO:0086069=IMP, GO:0014704=TAS, GO:0086005=IEA, GO:0003294=IEA, GO:0035050=IEA, GO:0060413=IEA, GO:0060412=IEA, GO:0003193=IMP, GO:0003174=IMP, GO:0001525=IEP, GO:0086064=IDA, GO:0003151=IMP, GO:0003071=IEA, GO:0001501=IEA, GO:1900133=IEA, GO:0005887=IDA, GO:0086077=IDA, GO:0055117=IMP, GO:0086014=IMP, GO:0005921=IDA, GO:0005922=IDA, GO:0086015=IEA} AV node cell to bundle of His cell communication by electrical coupling, angiogenesis, artery morphogenesis, atrial septum development, atrial septum morphogenesis, atrial ventricular junction remodeling, bundle of His cell to Purkinje myocyte communication, cardiac conduction system development, cell communication by electrical coupling involved in cardiac conduction, embryonic heart tube development, embryonic limb morphogenesis, foramen ovale closure, gap junction assembly, mitral valve development, outflow tract morphogenesis, pulmonary valve formation, regulation of SA node cell action potential, regulation of atrial cardiac muscle cell action potential, regulation of atrial cardiac muscle cell membrane depolarization, regulation of cardiac muscle contraction, regulation of heart rate by cardiac conduction, regulation of membrane depolarization involved in regulation of cardiac muscle cell action potential, regulation of renin secretion into blood stream, regulation of vasodilation, regulation of ventricular cardiac muscle cell action potential, regulation of ventricular cardiac muscle cell membrane depolarization, regulation of ventricular cardiac muscle cell membrane repolarization, renal system process involved in regulation of systemic arterial blood pressure, septum primum development, skeletal system development, ventricular septum development, ventricular septum morphogenesis connexon complex, gap junction, integral to plasma membrane, intercalated disc gap junction channel activity involved in AV node cell-bundle of His cell electrical coupling, gap junction channel activity involved in cardiac conduction electrical coupling, gap junction hemi-channel activity Human GJA8 PINC UniProtKB {GO:0005887=PMID:7796604, GO:0002088=GO_REF:0000019, GO:0006810=PMID:7796604, GO:0007267=GO_REF:0000019, GO:0051260=GO_REF:0000019, GO:0005922=GO_REF:0000019, GO:0007601=PMID:9497259, GO:0015267=PMID:7796604} P48165 Gap junction alpha-8 protein protein 20030904 {GO:0005887=TAS, GO:0002088=IEA, GO:0006810=TAS, GO:0007267=IEA, GO:0051260=IEA, GO:0005922=IEA, GO:0007601=TAS, GO:0015267=TAS} cell-cell signaling, lens development in camera-type eye, protein homooligomerization, transport, visual perception connexon complex, integral to plasma membrane channel activity Human GJA9 UniProtKB UniProtKB {GO:0007154=GO_REF:0000002, GO:0005922=GO_REF:0000002, GO:0016021=GO_REF:0000037} P57773 Gap junction alpha-9 protein protein 20130413 {GO:0007154=IEA, GO:0005922=IEA, GO:0016021=IEA} cell communication connexon complex, integral to membrane Human UniProtKB-KW:KW-0812 GJB1 Reactome UniProtKB {GO:0005243=GO_REF:0000019, GO:0005783=GO_REF:0000019, GO:0007267=PMID:8266101, GO:0016264=Reactome:REACT_9509, GO:0051259=GO_REF:0000019, GO:0042803=GO_REF:0000019, GO:0007399=PMID:8266101, GO:0007154=GO_REF:0000002, GO:0006810=PMID:2875078, GO:0005789=Reactome:REACT_9494, GO:0005922=GO_REF:0000002, GO:0016021=GO_REF:0000037, GO:0015868=GO_REF:0000019, GO:0016044=Reactome:REACT_11123} P08034 Gap junction beta-1 protein protein 20130213 {GO:0005243=IEA, GO:0005783=IEA, GO:0007267=TAS, GO:0016264=TAS, GO:0051259=IEA, GO:0042803=IEA, GO:0007399=TAS, GO:0007154=IEA, GO:0006810=TAS, GO:0005789=TAS, GO:0005922=IEA, GO:0016021=IEA, GO:0015868=IEA, GO:0016044=TAS} cell communication, cell-cell signaling, cellular membrane organization, gap junction assembly, nervous system development, protein oligomerization, purine ribonucleotide transport, transport connexon complex, endoplasmic reticulum, endoplasmic reticulum membrane, integral to membrane gap junction channel activity, protein homodimerization activity Human GJB2 Reactome UniProtKB {GO:0030539=GO_REF:0000019, GO:0005793=Reactome:REACT_21353, GO:0005243=GO_REF:0000019, GO:0005886=Reactome:REACT_21353, GO:0007605=GO_REF:0000037, GO:0006810=PMID:1324944, GO:0007267=GO_REF:0000019, GO:0005922=GO_REF:0000002, GO:0016264=Reactome:REACT_9509, GO:0016021=GO_REF:0000037, GO:0016328=GO_REF:0000019, GO:0016044=Reactome:REACT_11123} P29033 Gap junction beta-2 protein protein 20130213 {GO:0030539=IEA, GO:0005793=TAS, GO:0005243=IEA, GO:0005886=TAS, GO:0007605=IEA, GO:0006810=TAS, GO:0007267=IEA, GO:0005922=IEA, GO:0016264=TAS, GO:0016021=IEA, GO:0016328=IEA, GO:0016044=TAS} cell-cell signaling, cellular membrane organization, gap junction assembly, male genitalia development, sensory perception of sound, transport connexon complex, endoplasmic reticulum-Golgi intermediate compartment, integral to membrane, lateral plasma membrane, plasma membrane gap junction channel activity Human GJB3 UniProtKB UniProtKB {GO:0005243=PMID:9704026, GO:0005737=GO_REF:0000019, GO:0007154=GO_REF:0000029, GO:0007605=GO_REF:0000019, GO:0005921=PMID:9704026, GO:0043588=GO_REF:0000019, GO:0005922=GO_REF:0000002, GO:0001890=GO_REF:0000019, GO:0016021=GO_REF:0000037, GO:0001701=GO_REF:0000019} O75712 Gap junction beta-3 protein protein 20021104 {GO:0005243=NAS, GO:0005737=IEA, GO:0007154=NAS, GO:0007605=IEA, GO:0005921=NAS, GO:0043588=IEA, GO:0005922=IEA, GO:0001890=IEA, GO:0016021=IEA, GO:0001701=IEA} cell communication, in utero embryonic development, placenta development, sensory perception of sound, skin development connexon complex, cytoplasm, gap junction, integral to membrane gap junction channel activity Human GJB5 PINC UniProtKB {GO:0007154=GO_REF:0000002, GO:0008544=PMID:9843209, GO:0060713=GO_REF:0000019, GO:0060708=GO_REF:0000019, GO:0005922=GO_REF:0000002, GO:0016021=GO_REF:0000037} O95377 Gap junction beta-5 protein protein 20030904 {GO:0007154=IEA, GO:0008544=TAS, GO:0060713=IEA, GO:0060708=IEA, GO:0005922=IEA, GO:0016021=IEA} cell communication, epidermis development, labyrinthine layer morphogenesis, spongiotrophoblast differentiation connexon complex, integral to membrane Human GJB6 HPA UniProtKB {GO:0042471=GO_REF:0000019, GO:0007154=GO_REF:0000002, GO:0005886=GO_REF:0000052, GO:0007605=GO_REF:0000019, GO:0005922=GO_REF:0000002, GO:0016021=GO_REF:0000037, GO:0043231=GO_REF:0000052} O95452 Gap junction beta-6 protein protein 20101115 {GO:0042471=IEA, GO:0007154=IEA, GO:0005886=IDA, GO:0007605=IEA, GO:0005922=IEA, GO:0016021=IEA, GO:0043231=IDA} cell communication, ear morphogenesis, sensory perception of sound connexon complex, integral to membrane, intracellular membrane-bounded organelle, plasma membrane Human GJB7 UniProtKB UniProtKB {GO:0007154=GO_REF:0000002, GO:0005922=GO_REF:0000002, GO:0016021=GO_REF:0000037} Q6PEY0 Gap junction beta-7 protein protein 20130413 {GO:0007154=IEA, GO:0005922=IEA, GO:0016021=IEA} cell communication connexon complex, integral to membrane Human UniProtKB-KW:KW-0812 GJC1 BHF-UCL UniProtKB {GO:0005243=GO_REF:0000019, GO:0005886=Reactome:REACT_16989, GO:0007268=Reactome:REACT_13685, GO:0016264=Reactome:REACT_9509, GO:0048738=GO_REF:0000019, GO:0007154=GO_REF:0000002, GO:0006936=PMID:7966354, GO:0014704=PMID:23348765, GO:0005789=Reactome:REACT_9410, GO:0006810=PMID:7966354, GO:0007043=PMID:7966354, GO:0086014=PMID:23348765, GO:0005921=PMID:7966354, GO:0005922=GO_REF:0000019, GO:0016021=GO_REF:0000037, GO:0048468=GO_REF:0000019, GO:0005216=GO_REF:0000019, GO:0007601=GO_REF:0000019, GO:0001570=GO_REF:0000019, GO:0016044=Reactome:REACT_11123} P36383 Gap junction gamma-1 protein protein 20130130 {GO:0005243=IEA, GO:0005886=TAS, GO:0007268=TAS, GO:0016264=TAS, GO:0048738=IEA, GO:0007154=IEA, GO:0006936=TAS, GO:0014704=TAS, GO:0005789=TAS, GO:0006810=NAS, GO:0007043=TAS, GO:0086014=TAS, GO:0005921=TAS, GO:0005922=IEA, GO:0016021=IEA, GO:0048468=IEA, GO:0005216=IEA, GO:0007601=IEA, GO:0001570=IEA, GO:0016044=TAS} cardiac muscle tissue development, cell communication, cell development, cell-cell junction assembly, cellular membrane organization, gap junction assembly, muscle contraction, regulation of atrial cardiac muscle cell action potential, synaptic transmission, transport, vasculogenesis, visual perception connexon complex, endoplasmic reticulum membrane, gap junction, integral to membrane, intercalated disc, plasma membrane gap junction channel activity, ion channel activity Human GJC2 ENSEMBL UniProtKB {GO:0008219=GO_REF:0000037, GO:0005243=GO_REF:0000019, GO:0043209=GO_REF:0000019, GO:0007267=GO_REF:0000019, GO:0009636=GO_REF:0000019, GO:0005922=GO_REF:0000002, GO:0016021=GO_REF:0000037} Q5T442 Gap junction gamma-2 protein protein 20130413 {GO:0008219=IEA, GO:0005243=IEA, GO:0043209=IEA, GO:0007267=IEA, GO:0009636=IEA, GO:0005922=IEA, GO:0016021=IEA} cell death, cell-cell signaling, response to toxic substance connexon complex, integral to membrane, myelin sheath gap junction channel activity Human Ensembl:ENSMUSP00000104421 GJD2 Reactome UniProtKB {GO:0005243=Reactome:REACT_16981, GO:0007154=GO_REF:0000029, GO:0005886=Reactome:REACT_16989, GO:0007268=Reactome:REACT_13685, GO:0005921=GO_REF:0000029, GO:0005922=GO_REF:0000002, GO:0001508=GO_REF:0000019, GO:0016021=GO_REF:0000037, GO:0007601=GO_REF:0000019} Q9UKL4 Gap junction delta-2 protein protein 20130213 {GO:0005243=TAS, GO:0007154=NAS, GO:0005886=TAS, GO:0007268=TAS, GO:0005921=NAS, GO:0005922=IEA, GO:0001508=IEA, GO:0016021=IEA, GO:0007601=IEA} cell communication, regulation of action potential, synaptic transmission, visual perception connexon complex, gap junction, integral to membrane, plasma membrane gap junction channel activity Human GJD3 IntAct UniProtKB {GO:0005515=PMID:12154091, GO:0007154=PMID:12154091, GO:0009986=PMID:12154091, GO:0005887=PMID:12154091, GO:0005922=PMID:12154091, GO:0016264=PMID:12154091, GO:0016021=GO_REF:0000038, GO:0005216=GO_REF:0000019} Q8N144 Gap junction delta-3 protein protein 20130415 {GO:0005515=IPI, GO:0007154=TAS, GO:0009986=IDA, GO:0005887=TAS, GO:0005922=IDA, GO:0016264=IDA, GO:0016021=IEA, GO:0005216=IEA} cell communication, gap junction assembly cell surface, connexon complex, integral to membrane, integral to plasma membrane ion channel activity, protein binding Human UniProtKB:Q07157 GJD4 UniProtKB UniProtKB {GO:0007154=GO_REF:0000002, GO:0005922=GO_REF:0000002, GO:0016021=GO_REF:0000037} Q96KN9 Gap junction delta-4 protein protein 20130413 {GO:0007154=IEA, GO:0005922=IEA, GO:0016021=IEA} cell communication connexon complex, integral to membrane Human UniProtKB-KW:KW-0812 GK BHF-UCL UniProtKB {GO:0005515=PMID:21988832, GO:0004370=PMID:8651297, GO:0019563=GO_REF:0000041, GO:0005975=GO_REF:0000002, GO:0005741=GO_REF:0000029, GO:0044281=Reactome:REACT_111217, GO:0006072=GO_REF:0000002, GO:0005524=GO_REF:0000037, GO:0006071=PMID:8499898, GO:0046167=PMID:8651297, GO:0005829=Reactome:REACT_724, GO:0005737=GO_REF:0000029, GO:0019432=Reactome:REACT_1190, GO:0006641=PMID:8651297, GO:0044255=Reactome:REACT_22279} P32189 Glycerol kinase protein 20110817 {GO:0005515=IPI, GO:0004370=IMP, GO:0019563=IEA, GO:0005975=IEA, GO:0005741=NAS, GO:0044281=TAS, GO:0006072=IEA, GO:0005524=IEA, GO:0006071=IMP, GO:0046167=IMP, GO:0005829=TAS, GO:0005737=NAS, GO:0019432=TAS, GO:0006641=IMP, GO:0044255=TAS} carbohydrate metabolic process, cellular lipid metabolic process, glycerol catabolic process, glycerol metabolic process, glycerol-3-phosphate biosynthetic process, glycerol-3-phosphate metabolic process, small molecule metabolic process, triglyceride biosynthetic process, triglyceride metabolic process cytoplasm, cytosol, mitochondrial outer membrane ATP binding, glycerol kinase activity, protein binding Human GK5 UniPathway UniProtKB {GO:0019563=GO_REF:0000041, GO:0004370=GO_REF:0000003, GO:0005975=GO_REF:0000002, GO:0016773=GO_REF:0000002, GO:0005524=GO_REF:0000037} Q6ZS86 Putative glycerol kinase 5 protein 20130413 {GO:0019563=IEA, GO:0004370=IEA, GO:0005975=IEA, GO:0016773=IEA, GO:0005524=IEA} carbohydrate metabolic process, glycerol catabolic process ATP binding, glycerol kinase activity, phosphotransferase activity, alcohol group as acceptor Human UniPathway:UPA00618 GKAP1 UniProtKB UniProtKB {GO:0007165=GO_REF:0000024, GO:0005794=GO_REF:0000024, GO:0016301=GO_REF:0000038} Q5VSY0 G kinase-anchoring protein 1 protein 20040430 {GO:0007165=ISS, GO:0005794=ISS, GO:0016301=IEA} signal transduction Golgi apparatus kinase activity Human UniProtKB:Q9JMB0 GKN1 UniProtKB UniProtKB {GO:0003674=GO_REF:0000015, GO:0008284=GO_REF:0000019, GO:0007586=PMID:10835488, GO:0005576=GO_REF:0000039, GO:0051781=GO_REF:0000037, GO:0005575=GO_REF:0000015, GO:0030141=GO_REF:0000019, GO:0008083=GO_REF:0000019} Q9NS71 Gastrokine-1 protein 20061026 {GO:0003674=ND, GO:0008284=IEA, GO:0007586=NAS, GO:0005576=IEA, GO:0051781=IEA, GO:0005575=ND, GO:0030141=IEA, GO:0008083=IEA} digestion, positive regulation of cell division, positive regulation of cell proliferation cellular_component, extracellular region, secretory granule growth factor activity, molecular_function Human GKN2 UniProtKB UniProtKB {GO:0005576=GO_REF:0000039} Q86XP6 Gastrokine-2 protein 20130413 {GO:0005576=IEA} extracellular region Human UniProtKB-SubCell:SL-0243 GLA Reactome UniProtKB {GO:0006665=Reactome:REACT_19323, GO:0005515=PMID:1332979, GO:0009311=PMID:39940, GO:0005794=PMID:1332979, GO:0006687=Reactome:REACT_116105, GO:0046477=GO_REF:0000024, GO:0052692=GO_REF:0000003, GO:0046479=PMID:2160973, GO:0005102=PMID:1332979, GO:0016936=GO_REF:0000019, GO:0016139=GO_REF:0000033, GO:0005576=PMID:1332979, GO:0044281=Reactome:REACT_111217, GO:0003824=PMID:39940, GO:0005764=PMID:1332979, GO:0042803=PMID:6256390, GO:0005737=PMID:1332979, GO:0051001=GO_REF:0000024, GO:0016787=PMID:7911050, GO:0045019=GO_REF:0000024, GO:0004557=Reactome:REACT_115752, GO:0043202=Reactome:REACT_115752} P06280 Alpha-galactosidase A protein 20110921 {GO:0006665=TAS, GO:0005515=IPI, GO:0009311=IDA, GO:0005794=IMP, GO:0006687=TAS, GO:0046477=ISS, GO:0052692=IEA, GO:0046479=TAS, GO:0005102=IDA, GO:0016936=IEA, GO:0016139=IBA, GO:0005576=IMP, GO:0044281=TAS, GO:0003824=IDA, GO:0005764=IMP, GO:0042803=IDA, GO:0005737=IMP, GO:0051001=ISS, GO:0016787=TAS, GO:0045019=ISS, GO:0004557=TAS, GO:0043202=TAS} glycoside catabolic process, glycosphingolipid catabolic process, glycosphingolipid metabolic process, glycosylceramide catabolic process, negative regulation of nitric oxide biosynthetic process, negative regulation of nitric-oxide synthase activity, oligosaccharide metabolic process, small molecule metabolic process, sphingolipid metabolic process Golgi apparatus, cytoplasm, extracellular region, lysosomal lumen, lysosome alpha-galactosidase activity, catalytic activity, galactoside binding, hydrolase activity, protein binding, protein homodimerization activity, raffinose alpha-galactosidase activity, receptor binding Human GLB1 Reactome UniProtKB {GO:0005515=PMID:15498789, GO:0006665=Reactome:REACT_19323, GO:0004565=PMID:3143362, GO:0048471=GO_REF:0000039, GO:0006687=Reactome:REACT_116105, GO:0005975=Reactome:REACT_474, GO:0019388=GO_REF:0000019, GO:0016936=GO_REF:0000019, GO:0006027=Reactome:REACT_120752, GO:0044281=Reactome:REACT_111217, GO:0005764=GO_REF:0000019, GO:0004553=GO_REF:0000002, GO:0042339=Reactome:REACT_121288, GO:0042340=Reactome:REACT_121313, GO:0030203=Reactome:REACT_121315, GO:0043202=Reactome:REACT_121086} P16278 Beta-galactosidase protein 20110921 {GO:0005515=IPI, GO:0006665=TAS, GO:0004565=TAS, GO:0048471=IEA, GO:0006687=TAS, GO:0005975=TAS, GO:0019388=IEA, GO:0016936=IEA, GO:0006027=TAS, GO:0044281=TAS, GO:0005764=IEA, GO:0004553=IEA, GO:0042339=TAS, GO:0042340=TAS, GO:0030203=TAS, GO:0043202=TAS} carbohydrate metabolic process, galactose catabolic process, glycosaminoglycan catabolic process, glycosaminoglycan metabolic process, glycosphingolipid metabolic process, keratan sulfate catabolic process, keratan sulfate metabolic process, small molecule metabolic process, sphingolipid metabolic process lysosomal lumen, lysosome, perinuclear region of cytoplasm beta-galactosidase activity, galactoside binding, hydrolase activity, hydrolyzing O-glycosyl compounds, protein binding Human GLB1L UniProtKB UniProtKB {GO:0004565=GO_REF:0000002, GO:0005975=GO_REF:0000002, GO:0005576=GO_REF:0000039, GO:0004553=GO_REF:0000002} Q6UWU2 Beta-galactosidase-1-like protein protein 20130413 {GO:0004565=IEA, GO:0005975=IEA, GO:0005576=IEA, GO:0004553=IEA} carbohydrate metabolic process extracellular region beta-galactosidase activity, hydrolase activity, hydrolyzing O-glycosyl compounds Human UniProtKB-SubCell:SL-0243 GLB1L2 UniProtKB UniProtKB {GO:0004565=GO_REF:0000002, GO:0005975=GO_REF:0000002, GO:0005576=GO_REF:0000039, GO:0004553=GO_REF:0000002} Q8IW92 Beta-galactosidase-1-like protein 2 protein 20130413 {GO:0004565=IEA, GO:0005975=IEA, GO:0005576=IEA, GO:0004553=IEA} carbohydrate metabolic process extracellular region beta-galactosidase activity, hydrolase activity, hydrolyzing O-glycosyl compounds Human UniProtKB-SubCell:SL-0243 GLCCI1 ENSEMBL UniProtKB {GO:0005737=GO_REF:0000019} Q86VQ1 Glucocorticoid-induced transcript 1 protein protein 20130413 {GO:0005737=IEA} cytoplasm Human Ensembl:ENSMUSP00000069444 GLCE Reactome UniProtKB {GO:0005794=GO_REF:0000024, GO:0000139=GO_REF:0000039, GO:0005975=Reactome:REACT_474, GO:0050379=PMID:15853773, GO:0016857=GO_REF:0000024, GO:0047464=PMID:20118238, GO:0044281=Reactome:REACT_111217, GO:0015012=PMID:20118238, GO:0016021=GO_REF:0000037, GO:0030203=Reactome:REACT_121315, GO:0006024=Reactome:REACT_121248, GO:0030210=GO_REF:0000024} O94923 D-glucuronyl C5-epimerase protein 20130301 {GO:0005794=ISS, GO:0000139=IEA, GO:0005975=TAS, GO:0050379=IDA, GO:0016857=ISS, GO:0047464=IMP, GO:0044281=TAS, GO:0015012=IDA, GO:0016021=IEA, GO:0030203=TAS, GO:0006024=TAS, GO:0030210=ISS} carbohydrate metabolic process, glycosaminoglycan biosynthetic process, glycosaminoglycan metabolic process, heparan sulfate proteoglycan biosynthetic process, heparin biosynthetic process, small molecule metabolic process Golgi apparatus, Golgi membrane, integral to membrane UDP-glucuronate 5'-epimerase activity, heparosan-N-sulfate-glucuronate 5-epimerase activity, racemase and epimerase activity, acting on carbohydrates and derivatives Human GLDC UniProtKB UniProtKB {GO:0005739=GO_REF:0000039, GO:0030170=GO_REF:0000002, GO:0009055=PMID:2268343, GO:0006546=GO_REF:0000002, GO:0004375=GO_REF:0000003, GO:0016829=GO_REF:0000002} P23378 "Glycine dehydrogenase ""decarboxylating"", mitochondrial" protein 20060428 {GO:0005739=IEA, GO:0030170=IEA, GO:0009055=TAS, GO:0006546=IEA, GO:0004375=IEA, GO:0016829=IEA} glycine catabolic process mitochondrion electron carrier activity, glycine dehydrogenase (decarboxylating) activity, lyase activity, pyridoxal phosphate binding Human GLE1 PINC UniProtKB {GO:0005737=GO_REF:0000039, GO:0006406=PMID:9618489, GO:0016973=GO_REF:0000002, GO:0005643=GO_REF:0000039, GO:0015031=GO_REF:0000037} Q53GS7 Nucleoporin GLE1 protein 20061106 {GO:0005737=IEA, GO:0006406=TAS, GO:0016973=IEA, GO:0005643=IEA, GO:0015031=IEA} mRNA export from nucleus, poly(A)+ mRNA export from nucleus, protein transport cytoplasm, nuclear pore Human GLG1 PINC UniProtKB {GO:0031012=GO_REF:0000019, GO:0016020=GO_REF:0000002, GO:0000139=GO_REF:0000039, GO:0060349=GO_REF:0000019, GO:0005102=PMID:7531823, GO:0032330=GO_REF:0000019, GO:0016021=GO_REF:0000037, GO:0010955=GO_REF:0000019, GO:0030512=GO_REF:0000019} Q92896 Golgi apparatus protein 1 protein 20030904 {GO:0031012=IEA, GO:0016020=IEA, GO:0000139=IEA, GO:0060349=IEA, GO:0005102=TAS, GO:0032330=IEA, GO:0016021=IEA, GO:0010955=IEA, GO:0030512=IEA} bone morphogenesis, negative regulation of protein processing, negative regulation of transforming growth factor beta receptor signaling pathway, regulation of chondrocyte differentiation Golgi membrane, extracellular matrix, integral to membrane, membrane receptor binding Human GLI1 BHF-UCL UniProtKB {GO:0005515=PMID:22439934, GO:0008017=GO_REF:0000019, GO:0008284=PMID:12165851, GO:0044212=PMID:17035233, GO:0030324=GO_REF:0000019, GO:0021696=GO_REF:0000019, GO:0003705=GO_REF:0000019, GO:0021983=GO_REF:0000019, GO:0009954=GO_REF:0000019, GO:0005634=PMID:19878745, GO:0009953=GO_REF:0000019, GO:0007283=GO_REF:0000019, GO:0007224=PMID:11001584, GO:0005829=PMID:18559511, GO:0045880=PMID:17035233, GO:0005737=PMID:16229683, GO:0045944=PMID:9118802, GO:0090090=PMID:17035233, GO:0060032=GO_REF:0000019, GO:0021938=GO_REF:0000019, GO:0045740=PMID:12165851, GO:0048546=PMID:11001584, GO:0003677=PMID:9118802, GO:0001649=PMID:12165851, GO:0007418=GO_REF:0000019, GO:0009913=PMID:12165851, GO:0005929=GO_REF:0000019, GO:0008589=PMID:11238441, GO:0003682=GO_REF:0000019, GO:0008270=GO_REF:0000002, GO:0045893=PMID:11238441} P08151 Zinc finger protein GLI1 protein 20111120 {GO:0005515=IPI, GO:0008017=IEA, GO:0008284=IMP, GO:0044212=IDA, GO:0030324=IEA, GO:0021696=IEA, GO:0003705=IEA, GO:0021983=IEA, GO:0009954=IEA, GO:0005634=IDA, GO:0009953=IEA, GO:0007283=IEA, GO:0007224=TAS, GO:0005829=IDA, GO:0045880=IDA, GO:0005737=IDA, GO:0045944=IDA, GO:0090090=IMP, GO:0060032=IEA, GO:0021938=IEA, GO:0045740=IDA, GO:0048546=TAS, GO:0003677=IDA, GO:0001649=IDA, GO:0007418=IEA, GO:0009913=IDA, GO:0005929=IEA, GO:0008589=TAS, GO:0003682=IEA, GO:0008270=IEA, GO:0045893=IDA} cerebellar cortex morphogenesis, digestive tract morphogenesis, dorsal/ventral pattern formation, epidermal cell differentiation, lung development, negative regulation of canonical Wnt receptor signaling pathway, notochord regression, osteoblast differentiation, pituitary gland development, positive regulation of DNA replication, positive regulation of cell proliferation, positive regulation of smoothened signaling pathway, positive regulation of transcription from RNA polymerase II promoter, positive regulation of transcription, DNA-dependent, proximal/distal pattern formation, regulation of smoothened signaling pathway, smoothened signaling pathway, smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation, spermatogenesis, ventral midline development cilium, cytoplasm, cytosol, nucleus DNA binding, RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity, chromatin binding, microtubule binding, protein binding, transcription regulatory region DNA binding, zinc ion binding Human GLI2 ENSEMBL UniProtKB {GO:0005515=PMID:12435627, GO:0033089=GO_REF:0000024, GO:0007389=GO_REF:0000024, GO:0003700=GO_REF:0000019, GO:0044212=GO_REF:0000019, GO:0021696=GO_REF:0000019, GO:0021965=GO_REF:0000019, GO:0030879=GO_REF:0000024, GO:0007224=PMID:15994174, GO:0007507=GO_REF:0000019, GO:0048589=GO_REF:0000019, GO:0007411=GO_REF:0000019, GO:0060603=GO_REF:0000019, GO:0060032=GO_REF:0000019, GO:0021938=GO_REF:0000019, GO:0045740=PMID:12165851, GO:0000122=GO_REF:0000019, GO:0001701=GO_REF:0000019, GO:0007418=GO_REF:0000024, GO:0001501=GO_REF:0000019, GO:0002076=GO_REF:0000019, GO:0008270=PMID:8378770, GO:0045893=PMID:15175043, GO:0042733=GO_REF:0000019, GO:0021513=GO_REF:0000024, GO:0030324=GO_REF:0000019, GO:0008283=GO_REF:0000019, GO:0021983=GO_REF:0000019, GO:0005634=GO_REF:0000019, GO:0009954=GO_REF:0000019, GO:0060831=GO_REF:0000019, GO:0021517=GO_REF:0000024, GO:0021776=GO_REF:0000019, GO:0021775=GO_REF:0000019, GO:0005737=GO_REF:0000019, GO:0048666=GO_REF:0000024, GO:0045944=GO_REF:0000019, GO:0090103=GO_REF:0000019, GO:0042475=GO_REF:0000019, GO:0032331=GO_REF:0000019, GO:0001822=GO_REF:0000019, GO:0006915=GO_REF:0000019, GO:0021508=GO_REF:0000019, GO:0031512=GO_REF:0000019, GO:0048566=GO_REF:0000019, GO:0006351=GO_REF:0000037, GO:0009612=GO_REF:0000019, GO:0043565=GO_REF:0000019, GO:0071407=GO_REF:0000019, GO:0016020=GO_REF:0000019, GO:0045666=GO_REF:0000019, GO:0008589=GO_REF:0000019, GO:0003682=GO_REF:0000019, GO:0007442=GO_REF:0000019, GO:0060513=GO_REF:0000019, GO:0060322=GO_REF:0000019, GO:0035295=GO_REF:0000024, GO:0048754=GO_REF:0000019, GO:0030902=GO_REF:0000024} Q1PSW9 Zinc finger protein GLI2 protein 20130413 {GO:0005515=IPI, GO:0033089=ISS, GO:0007389=ISS, GO:0003700=IEA, GO:0044212=IEA, GO:0021696=IEA, GO:0021965=IEA, GO:0030879=ISS, GO:0007224=IDA, GO:0007507=IEA, GO:0048589=IEA, GO:0007411=IEA, GO:0060603=IEA, GO:0060032=IEA, GO:0021938=IEA, GO:0045740=IDA, GO:0000122=IEA, GO:0001701=IEA, GO:0007418=ISS, GO:0001501=IEA, GO:0002076=IEA, GO:0008270=IDA, GO:0045893=IDA, GO:0042733=IEA, GO:0021513=ISS, GO:0030324=IEA, GO:0008283=IEA, GO:0021983=IEA, GO:0005634=IEA, GO:0009954=IEA, GO:0060831=IEA, GO:0021517=ISS, GO:0021776=IEA, GO:0021775=IEA, GO:0005737=IEA, GO:0048666=ISS, GO:0045944=IEA, GO:0090103=IEA, GO:0042475=IEA, GO:0032331=IEA, GO:0001822=IEA, GO:0006915=IEA, GO:0021508=IEA, GO:0031512=IEA, GO:0048566=IEA, GO:0006351=IEA, GO:0009612=IEA, GO:0043565=IEA, GO:0071407=IEA, GO:0016020=IEA, GO:0045666=IEA, GO:0008589=IEA, GO:0003682=IEA, GO:0007442=IEA, GO:0060513=IEA, GO:0060322=IEA, GO:0035295=ISS, GO:0048754=IEA, GO:0030902=ISS} apoptotic process, axon guidance, branching morphogenesis of an epithelial tube, cell proliferation, cellular response to organic cyclic compound, cerebellar cortex morphogenesis, cochlea morphogenesis, developmental growth, embryonic digestive tract development, embryonic digit morphogenesis, floor plate formation, head development, heart development, hindbrain development, hindgut morphogenesis, in utero embryonic development, kidney development, lung development, mammary gland development, mammary gland duct morphogenesis, negative regulation of chondrocyte differentiation, negative regulation of transcription from RNA polymerase II promoter, neuron development, notochord regression, odontogenesis of dentin-containing tooth, osteoblast development, pattern specification process, pituitary gland development, positive regulation of DNA replication, positive regulation of T cell differentiation in thymus, positive regulation of neuron differentiation, positive regulation of transcription from RNA polymerase II promoter, positive regulation of transcription, DNA-dependent, prostatic bud formation, proximal/distal pattern formation, regulation of smoothened signaling pathway, response to mechanical stimulus, skeletal system development, smoothened signaling pathway, smoothened signaling pathway involved in dorsal/ventral neural tube patterning, smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation, smoothened signaling pathway involved in spinal cord motor neuron cell fate specification, smoothened signaling pathway involved in ventral spinal cord interneuron specification, spinal cord dorsal/ventral patterning, spinal cord ventral commissure morphogenesis, transcription, DNA-dependent, tube development, ventral midline development, ventral spinal cord development cytoplasm, membrane, motile primary cilium, nucleus chromatin binding, protein binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, transcription regulatory region DNA binding, zinc ion binding Human Ensembl:ENSMUSP00000054837 GLI3 HPA UniProtKB {GO:0005515=PMID:16371461, GO:0001656=GO_REF:0000019, GO:0046638=GO_REF:0000024, GO:0001658=GO_REF:0000019, GO:0003700=PMID:10077605, GO:0008013=PMID:17331723, GO:0048709=GO_REF:0000019, GO:0048704=GO_REF:0000019, GO:0048593=GO_REF:0000019, GO:0021861=GO_REF:0000019, GO:0043231=GO_REF:0000052, GO:0007224=PMID:11001584, GO:0046639=GO_REF:0000024, GO:0061005=GO_REF:0000019, GO:0007507=GO_REF:0000019, GO:0048589=GO_REF:0000019, GO:0021798=GO_REF:0000019, GO:0016485=GO_REF:0000019, GO:0007411=GO_REF:0000019, GO:0017053=GO_REF:0000019, GO:0035035=PMID:10075717, GO:0033077=GO_REF:0000024, GO:0070242=GO_REF:0000024, GO:0000122=PMID:19084012, GO:0001701=GO_REF:0000019, GO:0005929=PMID:16254602, GO:0022018=GO_REF:0000019, GO:0016592=PMID:17000779, GO:0042307=GO_REF:0000019, GO:0008270=GO_REF:0000002, GO:0045893=GO_REF:0000024, GO:0043586=GO_REF:0000019, GO:0021631=GO_REF:0000019, GO:0045892=PMID:19084012, GO:0042733=PMID:11001584, GO:0043585=PMID:11001584, GO:0060873=GO_REF:0000019, GO:0060594=GO_REF:0000019, GO:0060875=GO_REF:0000019, GO:0008285=GO_REF:0000019, GO:0042826=PMID:12435627, GO:0030324=GO_REF:0000019, GO:0021801=GO_REF:0000019, GO:0005634=GO_REF:0000052, GO:0009954=GO_REF:0000019, GO:0045879=GO_REF:0000024, GO:0060831=GO_REF:0000019, GO:0009952=GO_REF:0000019, GO:0005829=PMID:18559511, GO:0021776=GO_REF:0000019, GO:0021775=GO_REF:0000019, GO:0005737=PMID:10077605, GO:0045944=PMID:17000779, GO:0042475=GO_REF:0000019, GO:0060021=GO_REF:0000019, GO:0032332=GO_REF:0000019, GO:0035108=PMID:9354785, GO:0090090=PMID:17331723, GO:0043066=GO_REF:0000019, GO:0005730=GO_REF:0000052, GO:0002052=GO_REF:0000019, GO:0030318=GO_REF:0000019, GO:0048566=PMID:11001584, GO:0060840=GO_REF:0000019, GO:0006351=GO_REF:0000037, GO:0045669=GO_REF:0000019, GO:0060366=GO_REF:0000019, GO:0043565=GO_REF:0000019, GO:0060364=GO_REF:0000019, GO:0045665=GO_REF:0000019, GO:0048557=GO_REF:0000019, GO:0003682=GO_REF:0000019, GO:0007442=GO_REF:0000019, GO:0045060=GO_REF:0000024, GO:0060367=GO_REF:0000019} P10071 Transcriptional activator GLI3 protein 20080818 {GO:0005515=IPI, GO:0001656=IEA, GO:0046638=ISS, GO:0001658=IEA, GO:0003700=IDA, GO:0008013=IPI, GO:0048709=IEA, GO:0048704=IEA, GO:0048593=IEA, GO:0021861=IEA, GO:0043231=IDA, GO:0007224=TAS, GO:0046639=ISS, GO:0061005=IEA, GO:0007507=IEA, GO:0048589=IEA, GO:0021798=IEA, GO:0016485=IEA, GO:0007411=IEA, GO:0017053=IEA, GO:0035035=IPI, GO:0033077=ISS, GO:0070242=ISS, GO:0000122=IDA, GO:0001701=IEA, GO:0005929=IDA, GO:0022018=IEA, GO:0016592=IDA, GO:0042307=IEA, GO:0008270=IEA, GO:0045893=ISS, GO:0043586=IEA, GO:0021631=IEA, GO:0045892=IDA, GO:0042733=TAS, GO:0043585=TAS, GO:0060873=IEA, GO:0060594=IEA, GO:0060875=IEA, GO:0008285=IEA, GO:0042826=IDA, GO:0030324=IEA, GO:0021801=IEA, GO:0005634=IDA, GO:0009954=IEA, GO:0045879=ISS, GO:0060831=IEA, GO:0009952=IEA, GO:0005829=IDA, GO:0021776=IEA, GO:0021775=IEA, GO:0005737=IDA, GO:0045944=IDA, GO:0042475=IEA, GO:0060021=IEA, GO:0032332=IEA, GO:0035108=IMP, GO:0090090=IDA, GO:0043066=IEA, GO:0005730=IDA, GO:0002052=IEA, GO:0030318=IEA, GO:0048566=TAS, GO:0060840=IEA, GO:0006351=IEA, GO:0045669=IEA, GO:0060366=IEA, GO:0043565=IEA, GO:0060364=IEA, GO:0045665=IEA, GO:0048557=IEA, GO:0003682=IEA, GO:0007442=IEA, GO:0045060=ISS, GO:0060367=IEA} T cell differentiation in thymus, anterior semicircular canal development, anterior/posterior pattern specification, artery development, axon guidance, branching involved in ureteric bud morphogenesis, camera-type eye morphogenesis, cell differentiation involved in kidney development, cerebral cortex radial glia guided migration, developmental growth, embryonic digestive tract development, embryonic digestive tract morphogenesis, embryonic digit morphogenesis, embryonic skeletal system morphogenesis, forebrain dorsal/ventral pattern formation, forebrain radial glial cell differentiation, frontal suture morphogenesis, heart development, hindgut morphogenesis, in utero embryonic development, lambdoid suture morphogenesis, lateral ganglionic eminence cell proliferation, lateral semicircular canal development, limb morphogenesis, lung development, mammary gland specification, melanocyte differentiation, metanephros development, negative regulation of alpha-beta T cell differentiation, negative regulation of apoptotic process, negative regulation of canonical Wnt receptor signaling pathway, negative regulation of cell proliferation, negative regulation of neuron differentiation, negative regulation of smoothened signaling pathway, negative regulation of transcription from RNA polymerase II promoter, negative regulation of transcription, DNA-dependent, negative thymic T cell selection, nose morphogenesis, odontogenesis of dentin-containing tooth, oligodendrocyte differentiation, optic nerve morphogenesis, palate development, positive regulation of alpha-beta T cell differentiation, positive regulation of chondrocyte differentiation, positive regulation of neuroblast proliferation, positive regulation of osteoblast differentiation, positive regulation of protein import into nucleus, positive regulation of transcription from RNA polymerase II promoter, positive regulation of transcription, DNA-dependent, protein processing, proximal/distal pattern formation, sagittal suture morphogenesis, smoothened signaling pathway, smoothened signaling pathway involved in dorsal/ventral neural tube patterning, smoothened signaling pathway involved in spinal cord motor neuron cell fate specification, smoothened signaling pathway involved in ventral spinal cord interneuron specification, thymocyte apoptotic process, tongue development, transcription, DNA-dependent cilium, cytoplasm, cytosol, intracellular membrane-bounded organelle, mediator complex, nucleolus, nucleus, transcriptional repressor complex beta-catenin binding, chromatin binding, histone acetyltransferase binding, histone deacetylase binding, protein binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, zinc ion binding Human GLIPR1L2 UniProtKB UniProtKB {GO:0016021=GO_REF:0000037} Q4G1C9 GLIPR1-like protein 2 protein 20130413 {GO:0016021=IEA} integral to membrane Human UniProtKB-KW:KW-0812 GLIPR2 UniProtKB UniProtKB {GO:0000139=GO_REF:0000039, GO:0005576=GO_REF:0000002} Q9H4G4 Golgi-associated plant pathogenesis-related protein 1 protein 20130413 {GO:0000139=IEA, GO:0005576=IEA} Golgi membrane, extracellular region Human UniProtKB-SubCell:SL-0134 GLIS2 BHF-UCL UniProtKB {GO:0044212=GO_REF:0000024, GO:0005634=GO_REF:0000024, GO:0045879=GO_REF:0000024, GO:0000122=GO_REF:0000024, GO:0030154=GO_REF:0000037, GO:0043433=GO_REF:0000024, GO:0007399=GO_REF:0000037, GO:0005737=GO_REF:0000039, GO:0001077=GO_REF:0000024, GO:0016607=GO_REF:0000024, GO:0045944=GO_REF:0000024, GO:0008270=GO_REF:0000002, GO:0045893=GO_REF:0000024, GO:0045892=GO_REF:0000024} Q9BZE0 Zinc finger protein GLIS2 protein 20101220 {GO:0044212=ISS, GO:0005634=ISS, GO:0045879=ISS, GO:0000122=ISS, GO:0030154=IEA, GO:0043433=ISS, GO:0007399=IEA, GO:0005737=IEA, GO:0001077=ISS, GO:0016607=ISS, GO:0045944=ISS, GO:0008270=IEA, GO:0045893=ISS, GO:0045892=ISS} cell differentiation, negative regulation of sequence-specific DNA binding transcription factor activity, negative regulation of smoothened signaling pathway, negative regulation of transcription from RNA polymerase II promoter, negative regulation of transcription, DNA-dependent, nervous system development, positive regulation of transcription from RNA polymerase II promoter, positive regulation of transcription, DNA-dependent cytoplasm, nuclear speck, nucleus RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription, transcription regulatory region DNA binding, zinc ion binding Human UniProtKB:Q8VDL9 GLMN GOC UniProtKB {GO:0005515=PMID:11164950, GO:0031461=PMID:22405651, GO:0032434=PMID:22405651, GO:0050715=PMID:12604780, GO:0042130=PMID:12604780, GO:0005622=PMID:12604780, GO:0042692=PMID:11845407, GO:0045086=PMID:12604780, GO:0031463=PMID:22405651, GO:0040029=PMID:12604780, GO:0031462=PMID:22405651, GO:0055105=PMID:22405651, GO:0031464=PMID:22405651, GO:0031397=PMID:22405651, GO:0005171=PMID:11571281, GO:0001570=PMID:11845407, GO:0031625=PMID:22405651, GO:0042327=PMID:11571281} Q92990 Glomulin protein 20130413 {GO:0005515=IPI, GO:0031461=IPI, GO:0032434=IMP, GO:0050715=IMP, GO:0042130=IDA, GO:0005622=NAS, GO:0042692=IMP, GO:0045086=IMP, GO:0031463=IPI, GO:0040029=IMP, GO:0031462=IPI, GO:0055105=IGI, GO:0031464=IPI, GO:0031397=IGI, GO:0005171=IPI, GO:0001570=IMP, GO:0031625=IDA, GO:0042327=IDA} muscle cell differentiation, negative regulation of T cell proliferation, negative regulation of protein ubiquitination, positive regulation of cytokine secretion, positive regulation of interleukin-2 biosynthetic process, positive regulation of phosphorylation, regulation of gene expression, epigenetic, regulation of proteasomal ubiquitin-dependent protein catabolic process, vasculogenesis Cul2-RING ubiquitin ligase complex, Cul3-RING ubiquitin ligase complex, Cul4A-RING ubiquitin ligase complex, cullin-RING ubiquitin ligase complex, intracellular hepatocyte growth factor receptor binding, protein binding, ubiquitin protein ligase binding, ubiquitin-protein ligase inhibitor activity Human UniProtKB:P62877 GLO1 UniProtKB UniProtKB {GO:0005737=PMID:16130169, GO:0043066=PMID:11489834, GO:0006357=GO_REF:0000019, GO:0005975=GO_REF:0000019, GO:0006749=GO_REF:0000019, GO:0004462=PMID:11489834, GO:0009438=GO_REF:0000019, GO:0046872=GO_REF:0000037} Q04760 Lactoylglutathione lyase protein 20060130 {GO:0005737=TAS, GO:0043066=IDA, GO:0006357=IEA, GO:0005975=IEA, GO:0006749=IEA, GO:0004462=IDA, GO:0009438=IEA, GO:0046872=IEA} carbohydrate metabolic process, glutathione metabolic process, methylglyoxal metabolic process, negative regulation of apoptotic process, regulation of transcription from RNA polymerase II promoter cytoplasm lactoylglutathione lyase activity, metal ion binding Human GLOD4 UniProtKB UniProtKB {GO:0005739=GO_REF:0000039} Q9HC38 Glyoxalase domain-containing protein 4 protein 20130413 {GO:0005739=IEA} mitochondrion Human UniProtKB-SubCell:SL-0173 GLP1R Reactome UniProtKB {GO:0007190=PMID:8405712, GO:0006112=Reactome:REACT_1505, GO:0050796=Reactome:REACT_18325, GO:0005886=Reactome:REACT_22268, GO:0019933=PMID:7589461, GO:0008528=GO_REF:0000002, GO:0044281=Reactome:REACT_111217, GO:0016021=GO_REF:0000037, GO:0007204=PMID:7589461, GO:0004967=GO_REF:0000002, GO:0004888=PMID:8405712} P43220 Glucagon-like peptide 1 receptor protein 20130213 {GO:0007190=TAS, GO:0006112=TAS, GO:0050796=TAS, GO:0005886=TAS, GO:0019933=IDA, GO:0008528=IEA, GO:0044281=TAS, GO:0016021=IEA, GO:0007204=IDA, GO:0004967=IEA, GO:0004888=TAS} activation of adenylate cyclase activity, cAMP-mediated signaling, elevation of cytosolic calcium ion concentration, energy reserve metabolic process, regulation of insulin secretion, small molecule metabolic process integral to membrane, plasma membrane G-protein coupled peptide receptor activity, glucagon receptor activity, transmembrane signaling receptor activity Human GLP2R Reactome UniProtKB {GO:0008284=PMID:9990065, GO:0005886=Reactome:REACT_22268, GO:0004930=PMID:9990065, GO:0007188=GO_REF:0000019, GO:0016021=GO_REF:0000037, GO:0004967=GO_REF:0000019} O95838 Glucagon-like peptide 2 receptor protein 20130213 {GO:0008284=TAS, GO:0005886=TAS, GO:0004930=TAS, GO:0007188=IEA, GO:0016021=IEA, GO:0004967=IEA} adenylate cyclase-modulating G-protein coupled receptor signaling pathway, positive regulation of cell proliferation integral to membrane, plasma membrane G-protein coupled receptor activity, glucagon receptor activity Human GLRA1 UniProtKB UniProtKB {GO:0005515=PMID:11929858, GO:0006821=PMID:8137830, GO:0005230=GO_REF:0000002, GO:0030054=GO_REF:0000038, GO:0022824=GO_REF:0000002, GO:0005886=Reactome:REACT_25304, GO:0005783=GO_REF:0000019, GO:0051970=PMID:11973623, GO:0051291=GO_REF:0000019, GO:0043231=PMID:7506679, GO:0016934=PMID:7920629, GO:0001964=PMID:8298642, GO:0002087=GO_REF:0000019, GO:0034220=Reactome:REACT_25387, GO:0006936=PMID:11973623, GO:0007218=PMID:2155780, GO:0045211=GO_REF:0000038, GO:0042391=PMID:7920629, GO:0050884=GO_REF:0000019, GO:0007628=GO_REF:0000019, GO:0051260=GO_REF:0000019, GO:0006811=PMID:2155780, GO:0034707=GO_REF:0000037, GO:0055085=Reactome:REACT_15518, GO:2000344=PMID:11751269, GO:0030977=PMID:15748848, GO:0060080=GO_REF:0000019, GO:0005887=GO_REF:0000002, GO:0016594=GO_REF:0000002, GO:0016021=PMID:15952785, GO:0007340=GO_REF:0000019, GO:0001508=GO_REF:0000019, GO:0007601=GO_REF:0000019, GO:0060012=GO_REF:0000019, GO:0009897=GO_REF:0000019, GO:0060013=GO_REF:0000019} Q14C71 GLRA1 protein protein 20130413 {GO:0005515=IPI, GO:0006821=IDA, GO:0005230=IEA, GO:0030054=IEA, GO:0022824=IEA, GO:0005886=TAS, GO:0005783=IEA, GO:0051970=IMP, GO:0051291=IEA, GO:0043231=IDA, GO:0016934=IMP, GO:0001964=IMP, GO:0002087=IEA, GO:0034220=TAS, GO:0006936=IMP, GO:0007218=IDA, GO:0045211=IEA, GO:0042391=IMP, GO:0050884=IEA, GO:0007628=IEA, GO:0051260=IEA, GO:0006811=IDA, GO:0034707=IEA, GO:0055085=TAS, GO:2000344=IMP, GO:0030977=IDA, GO:0060080=IEA, GO:0005887=IEA, GO:0016594=IEA, GO:0016021=NAS, GO:0007340=IEA, GO:0001508=IEA, GO:0007601=IEA, GO:0060012=IEA, GO:0009897=IEA, GO:0060013=IEA} acrosome reaction, adult walking behavior, chloride transport, ion transmembrane transport, ion transport, muscle contraction, negative regulation of transmission of nerve impulse, neuromuscular process controlling posture, neuropeptide signaling pathway, positive regulation of acrosome reaction, protein heterooligomerization, protein homooligomerization, regulation of action potential, regulation of inhibitory postsynaptic membrane potential, regulation of membrane potential, regulation of respiratory gaseous exchange by neurological system process, righting reflex, startle response, synaptic transmission, glycinergic, transmembrane transport, visual perception cell junction, chloride channel complex, endoplasmic reticulum, external side of plasma membrane, integral to membrane, integral to plasma membrane, intracellular membrane-bounded organelle, plasma membrane, postsynaptic membrane extracellular ligand-gated ion channel activity, extracellular-glycine-gated chloride channel activity, glycine binding, protein binding, taurine binding, transmitter-gated ion channel activity Human UniProtKB-KW:KW-0628 GLRA2 Reactome UniProtKB {GO:0005230=GO_REF:0000002, GO:0022824=GO_REF:0000002, GO:0030054=GO_REF:0000037, GO:0005886=Reactome:REACT_25304, GO:0034707=GO_REF:0000037, GO:0055085=Reactome:REACT_15518, GO:0007416=GO_REF:0000019, GO:0016934=PMID:2155780, GO:0034220=Reactome:REACT_25387, GO:0005887=PMID:2155780, GO:0007218=PMID:2155780, GO:0045211=GO_REF:0000039, GO:0016594=PMID:2155780, GO:0006811=PMID:2155780} P23416 Glycine receptor subunit alpha-2 protein 20130301 {GO:0005230=IEA, GO:0022824=IEA, GO:0030054=IEA, GO:0005886=TAS, GO:0034707=IEA, GO:0055085=TAS, GO:0007416=IEA, GO:0016934=IDA, GO:0034220=TAS, GO:0005887=NAS, GO:0007218=IDA, GO:0045211=IEA, GO:0016594=IDA, GO:0006811=IDA} ion transmembrane transport, ion transport, neuropeptide signaling pathway, synapse assembly, transmembrane transport cell junction, chloride channel complex, integral to plasma membrane, plasma membrane, postsynaptic membrane extracellular ligand-gated ion channel activity, extracellular-glycine-gated chloride channel activity, glycine binding, transmitter-gated ion channel activity Human GLRB Reactome UniProtKB {GO:0005515=PMID:15215304, GO:0030054=GO_REF:0000037, GO:0005886=Reactome:REACT_25304, GO:0034707=GO_REF:0000037, GO:0007268=PMID:11929858, GO:0055085=Reactome:REACT_15518, GO:0051291=GO_REF:0000019, GO:0016933=PMID:11929858, GO:0007399=PMID:11929858, GO:0016934=Reactome:REACT_25304, GO:0001964=PMID:11929858, GO:0034220=Reactome:REACT_25387, GO:0007218=PMID:8717357, GO:0005887=PMID:8717357, GO:0045211=GO_REF:0000039, GO:0042391=GO_REF:0000019, GO:0016594=PMID:15748848, GO:0007628=GO_REF:0000019, GO:0007340=GO_REF:0000019, GO:0007601=GO_REF:0000019, GO:0060012=GO_REF:0000019, GO:0060013=GO_REF:0000019, GO:0006811=PMID:8717357} P48167 Glycine receptor subunit beta protein 20121220 {GO:0005515=IPI, GO:0030054=IEA, GO:0005886=TAS, GO:0034707=IEA, GO:0007268=IMP, GO:0055085=TAS, GO:0051291=IEA, GO:0016933=IMP, GO:0007399=IMP, GO:0016934=TAS, GO:0001964=IMP, GO:0034220=TAS, GO:0007218=IDA, GO:0005887=NAS, GO:0045211=IEA, GO:0042391=IEA, GO:0016594=IMP, GO:0007628=IEA, GO:0007340=IEA, GO:0007601=IEA, GO:0060012=IEA, GO:0060013=IEA, GO:0006811=IDA} acrosome reaction, adult walking behavior, ion transmembrane transport, ion transport, nervous system development, neuropeptide signaling pathway, protein heterooligomerization, regulation of membrane potential, righting reflex, startle response, synaptic transmission, synaptic transmission, glycinergic, transmembrane transport, visual perception cell junction, chloride channel complex, integral to plasma membrane, plasma membrane, postsynaptic membrane extracellular-glycine-gated chloride channel activity, extracellular-glycine-gated ion channel activity, glycine binding, protein binding Human GLRX Reactome UniProtKB {GO:0005739=GO_REF:0000019, GO:0015949=Reactome:REACT_21330, GO:0047485=PMID:16884690, GO:0015035=GO_REF:0000002, GO:0009055=GO_REF:0000002, GO:0055086=Reactome:REACT_1698, GO:0005634=GO_REF:0000019, GO:0045454=GO_REF:0000002, GO:0044281=Reactome:REACT_111217, GO:0015038=PMID:7851394, GO:0022900=GO_REF:0000037, GO:0005829=Reactome:REACT_1461} P35754 Glutaredoxin-1 protein 20130301 {GO:0005739=IEA, GO:0015949=TAS, GO:0047485=IPI, GO:0015035=IEA, GO:0009055=IEA, GO:0055086=TAS, GO:0005634=IEA, GO:0045454=IEA, GO:0044281=TAS, GO:0015038=TAS, GO:0022900=IEA, GO:0005829=TAS} cell redox homeostasis, electron transport chain, nucleobase-containing small molecule interconversion, nucleobase-containing small molecule metabolic process, small molecule metabolic process cytosol, mitochondrion, nucleus electron carrier activity, glutathione disulfide oxidoreductase activity, protein N-terminus binding, protein disulfide oxidoreductase activity Human GLRX2 GOC UniProtKB {GO:0042542=PMID:11397793, GO:0006355=PMID:11297543, GO:0010033=PMID:11397793, GO:0008794=PMID:11297543, GO:0051537=GO_REF:0000037, GO:0005730=GO_REF:0000052, GO:0015035=GO_REF:0000002, GO:0006915=PMID:11297543, GO:0009055=PMID:11297543, GO:0003756=PMID:11297543, GO:0006749=PMID:11397793, GO:0005634=GO_REF:0000052, GO:0009966=PMID:11297543, GO:0015038=PMID:11397793, GO:0030154=PMID:11297543, GO:0046872=GO_REF:0000037, GO:0009266=PMID:11397793, GO:0005739=PMID:11297543, GO:0006457=PMID:11397793, GO:0042262=PMID:11397793, GO:0051775=PMID:11297543, GO:0045454=PMID:11397793, GO:0022900=GO_REF:0000037} Q9NS18 Glutaredoxin-2, mitochondrial protein 20130413 {GO:0042542=IDA, GO:0006355=NAS, GO:0010033=IDA, GO:0008794=TAS, GO:0051537=IEA, GO:0005730=IDA, GO:0015035=IEA, GO:0006915=NAS, GO:0009055=NAS, GO:0003756=TAS, GO:0006749=TAS, GO:0005634=IDA, GO:0009966=NAS, GO:0015038=TAS, GO:0030154=NAS, GO:0046872=IEA, GO:0009266=NAS, GO:0005739=IDA, GO:0006457=TAS, GO:0042262=NAS, GO:0051775=TAS, GO:0045454=TAS, GO:0022900=IEA} DNA protection, apoptotic process, cell differentiation, cell redox homeostasis, electron transport chain, glutathione metabolic process, protein folding, regulation of signal transduction, regulation of transcription, DNA-dependent, response to hydrogen peroxide, response to organic substance, response to redox state, response to temperature stimulus mitochondrion, nucleolus, nucleus 2 iron, 2 sulfur cluster binding, arsenate reductase (glutaredoxin) activity, electron carrier activity, glutathione disulfide oxidoreductase activity, metal ion binding, protein disulfide isomerase activity, protein disulfide oxidoreductase activity Human GLRX3 IntAct UniProtKB {GO:0005515=PMID:10636891, GO:0010614=GO_REF:0000024, GO:0030018=GO_REF:0000039, GO:0051536=GO_REF:0000037, GO:0002026=PMID:18258855, GO:0005080=GO_REF:0000019, GO:0015035=GO_REF:0000002, GO:0009055=GO_REF:0000002, GO:0045454=GO_REF:0000002, GO:0005938=GO_REF:0000039, GO:0046872=GO_REF:0000037} O76003 Glutaredoxin-3 protein 20130415 {GO:0005515=IPI, GO:0010614=ISS, GO:0030018=IEA, GO:0051536=IEA, GO:0002026=ISS, GO:0005080=IEA, GO:0015035=IEA, GO:0009055=IEA, GO:0045454=IEA, GO:0005938=IEA, GO:0046872=IEA} cell redox homeostasis, negative regulation of cardiac muscle hypertrophy, regulation of the force of heart contraction Z disc, cell cortex electron carrier activity, iron-sulfur cluster binding, metal ion binding, protein binding, protein disulfide oxidoreductase activity, protein kinase C binding Human UniProtKB:Q04759 GLRX5 HPA UniProtKB {GO:0030097=GO_REF:0000024, GO:0005739=GO_REF:0000052, GO:0051537=GO_REF:0000037, GO:0015035=GO_REF:0000002, GO:0009055=GO_REF:0000002, GO:0005634=GO_REF:0000052, GO:0045454=GO_REF:0000002, GO:0046872=GO_REF:0000037} Q86SX6 Glutaredoxin-related protein 5, mitochondrial protein 20110516 {GO:0030097=ISS, GO:0005739=IDA, GO:0051537=IEA, GO:0015035=IEA, GO:0009055=IEA, GO:0005634=IDA, GO:0045454=IEA, GO:0046872=IEA} cell redox homeostasis, hemopoiesis mitochondrion, nucleus 2 iron, 2 sulfur cluster binding, electron carrier activity, metal ion binding, protein disulfide oxidoreductase activity Human GLS BHF-UCL UniProtKB {GO:0005515=PMID:16899818, GO:0006537=PMID:21757002, GO:0008652=Reactome:REACT_238, GO:0007268=Reactome:REACT_13685, GO:0044281=Reactome:REACT_111217, GO:0014047=Reactome:REACT_12591, GO:0007269=Reactome:REACT_13723, GO:0005829=GO_REF:0000039, GO:0005739=PMID:16899818, GO:0034641=Reactome:REACT_13, GO:0002087=GO_REF:0000019, GO:0051289=PMID:22049910, GO:0005759=Reactome:REACT_1700, GO:0004359=PMID:22049910, GO:0006543=PMID:22049910, GO:0007610=GO_REF:0000019, GO:0006541=GO_REF:0000002} O94925 Glutaminase kidney isoform, mitochondrial protein 20111201 {GO:0005515=IPI, GO:0006537=TAS, GO:0008652=TAS, GO:0007268=TAS, GO:0044281=TAS, GO:0014047=TAS, GO:0007269=TAS, GO:0005829=IEA, GO:0005739=IDA, GO:0034641=TAS, GO:0002087=IEA, GO:0051289=IDA, GO:0005759=TAS, GO:0004359=IDA, GO:0006543=IDA, GO:0007610=IEA, GO:0006541=IEA} behavior, cellular amino acid biosynthetic process, cellular nitrogen compound metabolic process, glutamate biosynthetic process, glutamate secretion, glutamine catabolic process, glutamine metabolic process, neurotransmitter secretion, protein homotetramerization, regulation of respiratory gaseous exchange by neurological system process, small molecule metabolic process, synaptic transmission cytosol, mitochondrial matrix, mitochondrion glutaminase activity, protein binding Human GLS2 Reactome UniProtKB {GO:0005515=PMID:11163757, GO:0006520=PMID:10620514, GO:0072593=PMID:20351271, GO:0007268=Reactome:REACT_13685, GO:0008652=Reactome:REACT_238, GO:0042981=PMID:20351271, GO:0044281=Reactome:REACT_111217, GO:0014047=Reactome:REACT_12591, GO:0007269=Reactome:REACT_13723, GO:0005739=PMID:20351271, GO:0034641=Reactome:REACT_13, GO:0005759=Reactome:REACT_1700, GO:0004359=GO_REF:0000003, GO:0006541=GO_REF:0000002} Q9UI32 Glutaminase liver isoform, mitochondrial protein 20130213 {GO:0005515=IPI, GO:0006520=TAS, GO:0072593=IMP, GO:0007268=TAS, GO:0008652=TAS, GO:0042981=IMP, GO:0044281=TAS, GO:0014047=TAS, GO:0007269=TAS, GO:0005739=IDA, GO:0034641=TAS, GO:0005759=TAS, GO:0004359=IEA, GO:0006541=IEA} cellular amino acid biosynthetic process, cellular amino acid metabolic process, cellular nitrogen compound metabolic process, glutamate secretion, glutamine metabolic process, neurotransmitter secretion, reactive oxygen species metabolic process, regulation of apoptotic process, small molecule metabolic process, synaptic transmission mitochondrial matrix, mitochondrion glutaminase activity, protein binding Human GLT8D1 HPA UniProtKB {GO:0005739=GO_REF:0000052, GO:0016757=GO_REF:0000037, GO:0016021=GO_REF:0000037} Q68CQ7 Glycosyltransferase 8 domain-containing protein 1 protein 20080205 {GO:0005739=IDA, GO:0016757=IEA, GO:0016021=IEA} integral to membrane, mitochondrion transferase activity, transferring glycosyl groups Human GLT8D2 UniProtKB UniProtKB {GO:0016757=GO_REF:0000037, GO:0016021=GO_REF:0000037} Q9H1C3 Glycosyltransferase 8 domain-containing protein 2 protein 20130413 {GO:0016757=IEA, GO:0016021=IEA} integral to membrane transferase activity, transferring glycosyl groups Human UniProtKB-KW:KW-0328 GLTP HGNC UniProtKB {GO:0005737=GO_REF:0000039, GO:0051861=PMID:15287756, GO:0016020=PMID:15901739, GO:0017089=PMID:15901739, GO:0046836=PMID:15901739, GO:0008289=PMID:15901739} Q9NZD2 Glycolipid transfer protein protein 20070412 {GO:0005737=IEA, GO:0051861=IDA, GO:0016020=IC, GO:0017089=IDA, GO:0046836=IDA, GO:0008289=IDA} glycolipid transport cytoplasm, membrane glycolipid binding, glycolipid transporter activity, lipid binding Human GLTPD1 InterPro UniProtKB {GO:0005737=GO_REF:0000002, GO:0051861=GO_REF:0000002, GO:0017089=GO_REF:0000002, GO:0046836=GO_REF:0000002} Q5TA50 Glycolipid transfer protein domain-containing protein 1 protein 20130413 {GO:0005737=IEA, GO:0051861=IEA, GO:0017089=IEA, GO:0046836=IEA} glycolipid transport cytoplasm glycolipid binding, glycolipid transporter activity Human InterPro:IPR014830 GLTPD2 InterPro UniProtKB {GO:0005737=GO_REF:0000002, GO:0051861=GO_REF:0000002, GO:0017089=GO_REF:0000002, GO:0046836=GO_REF:0000002} A6NH11 Glycolipid transfer protein domain-containing protein 2 protein 20130413 {GO:0005737=IEA, GO:0051861=IEA, GO:0017089=IEA, GO:0046836=IEA} glycolipid transport cytoplasm glycolipid binding, glycolipid transporter activity Human InterPro:IPR014830 GLTSCR1 IntAct UniProtKB {GO:0005515=PMID:17474147} Q9NZM4 Glioma tumor suppressor candidate region gene 1 protein protein 20130415 {GO:0005515=IPI} protein binding Human UniProtKB:P16333 GLTSCR2 HPA UniProtKB {GO:0005622=PMID:10196275, GO:0008150=GO_REF:0000015, GO:0003674=GO_REF:0000015, GO:0005730=GO_REF:0000052, GO:0043231=GO_REF:0000052} Q9NZM5 Glioma tumor suppressor candidate region gene 2 protein protein 20101115 {GO:0005622=NAS, GO:0008150=ND, GO:0003674=ND, GO:0005730=IDA, GO:0043231=IDA} biological_process intracellular, intracellular membrane-bounded organelle, nucleolus molecular_function Human GLUD1 HPA UniProtKB {GO:0005515=PMID:16959573, GO:0006520=GO_REF:0000002, GO:0006537=PMID:11032875, GO:0006538=PMID:11032875, GO:0070728=PMID:12742085, GO:0008652=Reactome:REACT_238, GO:0070403=PMID:12193607, GO:0016639=GO_REF:0000002, GO:0044281=Reactome:REACT_111217, GO:0005525=PMID:11032875, GO:0005524=GO_REF:0000037, GO:0042802=PMID:11903050, GO:0005739=GO_REF:0000052, GO:0004352=PMID:11903050, GO:0004353=PMID:11032875, GO:0034641=Reactome:REACT_13, GO:0005737=PMID:18688271, GO:0043531=PMID:12742085, GO:0005759=Reactome:REACT_1896, GO:0032024=PMID:11502802} P00367 Glutamate dehydrogenase 1, mitochondrial protein 20111111 {GO:0005515=IPI, GO:0006520=IEA, GO:0006537=IDA, GO:0006538=IDA, GO:0070728=IDA, GO:0008652=TAS, GO:0070403=IDA, GO:0016639=IEA, GO:0044281=TAS, GO:0005525=IDA, GO:0005524=IEA, GO:0042802=TAS, GO:0005739=IDA, GO:0004352=IDA, GO:0004353=IDA, GO:0034641=TAS, GO:0005737=IDA, GO:0043531=IDA, GO:0005759=TAS, GO:0032024=IMP} cellular amino acid biosynthetic process, cellular amino acid metabolic process, cellular nitrogen compound metabolic process, glutamate biosynthetic process, glutamate catabolic process, positive regulation of insulin secretion, small molecule metabolic process cytoplasm, mitochondrial matrix, mitochondrion "ADP binding, ATP binding, GTP binding, NAD+ binding, glutamate dehydrogenase (NAD+) activity, glutamate dehydrogenase NAD(P)+"" activity, identical protein binding, leucine binding, oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor, protein binding""" Human GLUD2 HPA UniProtKB {GO:0005739=GO_REF:0000052, GO:0004352=PMID:8207021, GO:0004353=PMID:11032875, GO:0005737=PMID:18688271, GO:0043531=PMID:12742085, GO:0006536=PMID:8207021, GO:0006537=PMID:11032875, GO:0006538=PMID:11032875, GO:0070728=PMID:12742085, GO:0005525=PMID:11032875, GO:0055114=PMID:8207021} P49448 Glutamate dehydrogenase 2, mitochondrial protein 20111111 {GO:0005739=IDA, GO:0004352=IDA, GO:0004353=IDA, GO:0005737=IDA, GO:0043531=IDA, GO:0006536=IDA, GO:0006537=IDA, GO:0006538=IDA, GO:0070728=IDA, GO:0005525=IDA, GO:0055114=IDA} glutamate biosynthetic process, glutamate catabolic process, glutamate metabolic process, oxidation-reduction process cytoplasm, mitochondrion "ADP binding, GTP binding, glutamate dehydrogenase (NAD+) activity, glutamate dehydrogenase NAD(P)+"" activity, leucine binding""" Human GLUL BHF-UCL UniProtKB {GO:0008283=PMID:18662667, GO:0007268=Reactome:REACT_13685, GO:0044281=Reactome:REACT_111217, GO:0005829=Reactome:REACT_1171, GO:0042802=PMID:21988832, GO:0005739=GO_REF:0000039, GO:0034641=Reactome:REACT_13, GO:0004351=GO_REF:0000003, GO:0004356=Reactome:REACT_1171, GO:0043204=GO_REF:0000019, GO:0051260=GO_REF:0000019, GO:0043679=GO_REF:0000019, GO:0032024=GO_REF:0000019, GO:0050679=GO_REF:0000019, GO:0005791=GO_REF:0000019, GO:0030145=GO_REF:0000019, GO:0000287=GO_REF:0000019, GO:0006538=PMID:21757002, GO:0051968=GO_REF:0000019, GO:0008652=Reactome:REACT_238, GO:0005524=GO_REF:0000019, GO:0009749=GO_REF:0000019, GO:0043234=GO_REF:0000019, GO:0045503=GO_REF:0000019, GO:0001504=Reactome:REACT_13594, GO:0016595=GO_REF:0000019, GO:0006542=PMID:21757002} P15104 Glutamine synthetase protein 20111201 {GO:0008283=IDA, GO:0007268=TAS, GO:0044281=TAS, GO:0005829=TAS, GO:0042802=IPI, GO:0005739=IEA, GO:0034641=TAS, GO:0004351=IEA, GO:0004356=EXP, GO:0043204=IEA, GO:0051260=IEA, GO:0043679=IEA, GO:0032024=IEA, GO:0050679=IEA, GO:0005791=IEA, GO:0030145=IEA, GO:0000287=IEA, GO:0006538=TAS, GO:0051968=IEA, GO:0008652=TAS, GO:0005524=IEA, GO:0009749=IEA, GO:0043234=IEA, GO:0045503=IEA, GO:0001504=TAS, GO:0016595=IEA, GO:0006542=TAS} cell proliferation, cellular amino acid biosynthetic process, cellular nitrogen compound metabolic process, glutamate catabolic process, glutamine biosynthetic process, neurotransmitter uptake, positive regulation of epithelial cell proliferation, positive regulation of insulin secretion, positive regulation of synaptic transmission, glutamatergic, protein homooligomerization, response to glucose stimulus, small molecule metabolic process, synaptic transmission axon terminus, cytosol, mitochondrion, perikaryon, protein complex, rough endoplasmic reticulum ATP binding, dynein light chain binding, glutamate binding, glutamate decarboxylase activity, glutamate-ammonia ligase activity, identical protein binding, magnesium ion binding, manganese ion binding Human GLYAT Reactome UniProtKB {GO:0005739=GO_REF:0000024, GO:0006637=PMID:7802672, GO:0032787=GO_REF:0000024, GO:0006805=Reactome:REACT_13433, GO:0016746=PMID:9202629, GO:0005759=Reactome:REACT_6953, GO:0047961=GO_REF:0000003, GO:0006544=GO_REF:0000024, GO:0009636=GO_REF:0000037, GO:0044281=Reactome:REACT_111217, GO:0047962=GO_REF:0000024} Q6IB77 Glycine N-acyltransferase protein 20130301 {GO:0005739=ISS, GO:0006637=TAS, GO:0032787=ISS, GO:0006805=TAS, GO:0016746=TAS, GO:0005759=TAS, GO:0047961=IEA, GO:0006544=ISS, GO:0009636=IEA, GO:0044281=TAS, GO:0047962=ISS} acyl-CoA metabolic process, glycine metabolic process, monocarboxylic acid metabolic process, response to toxic substance, small molecule metabolic process, xenobiotic metabolic process mitochondrial matrix, mitochondrion glycine N-acyltransferase activity, glycine N-benzoyltransferase activity, transferase activity, transferring acyl groups Human GLYATL1 UniProtKB UniProtKB {GO:0005739=GO_REF:0000002, GO:0047961=GO_REF:0000002, GO:0047946=GO_REF:0000003} Q969I3 Glycine N-acyltransferase-like protein 1 protein 20130413 {GO:0005739=IEA, GO:0047961=IEA, GO:0047946=IEA} mitochondrion glutamine N-acyltransferase activity, glycine N-acyltransferase activity Human EC:2.3.1.68 GLYATL3 InterPro UniProtKB {GO:0005739=GO_REF:0000002, GO:0047961=GO_REF:0000002} Q5SZD4 Glycine N-acyltransferase-like protein 3 protein 20130413 {GO:0005739=IEA, GO:0047961=IEA} mitochondrion glycine N-acyltransferase activity Human InterPro:IPR010313|InterPro:IPR015938 GLYCTK HPA UniProtKB {GO:0005515=PMID:19060904, GO:0005739=GO_REF:0000039, GO:0005737=GO_REF:0000052, GO:0005794=GO_REF:0000052, GO:0006468=PMID:16753811, GO:0005524=GO_REF:0000037, GO:0008887=PMID:16753811} Q8IVS8 Glycerate kinase protein 20101115 {GO:0005515=IPI, GO:0005739=IEA, GO:0005737=IDA, GO:0005794=IDA, GO:0006468=IDA, GO:0005524=IEA, GO:0008887=IDA} protein phosphorylation Golgi apparatus, cytoplasm, mitochondrion ATP binding, glycerate kinase activity, protein binding Human GLYR1 UniProtKB UniProtKB {GO:0050662=GO_REF:0000002, GO:0004616=GO_REF:0000002, GO:0016491=GO_REF:0000002, GO:0005634=GO_REF:0000039, GO:0035064=PMID:20850016, GO:0006098=GO_REF:0000002, GO:0003677=GO_REF:0000037} Q49A26 Putative oxidoreductase GLYR1 protein 20101105 {GO:0050662=IEA, GO:0004616=IEA, GO:0016491=IEA, GO:0005634=IEA, GO:0035064=IDA, GO:0006098=IEA, GO:0003677=IEA} pentose-phosphate shunt nucleus DNA binding, coenzyme binding, methylated histone residue binding, oxidoreductase activity, phosphogluconate dehydrogenase (decarboxylating) activity Human GM2A HPA UniProtKB {GO:0004563=GO_REF:0000019, GO:0006665=Reactome:REACT_19323, GO:0009313=GO_REF:0000019, GO:0006687=Reactome:REACT_116105, GO:0019915=GO_REF:0000019, GO:0006689=GO_REF:0000019, GO:0030149=GO_REF:0000029, GO:0005730=GO_REF:0000052, GO:0019377=GO_REF:0000029, GO:0044281=Reactome:REACT_111217, GO:0005764=GO_REF:0000029, GO:0030290=GO_REF:0000029, GO:0043231=GO_REF:0000052, GO:0005739=GO_REF:0000019, GO:0005737=GO_REF:0000052, GO:0007611=GO_REF:0000019, GO:0050885=GO_REF:0000019, GO:0043202=Reactome:REACT_115984} P17900 Ganglioside GM2 activator protein 20101115 {GO:0004563=IEA, GO:0006665=TAS, GO:0009313=IEA, GO:0006687=TAS, GO:0019915=IEA, GO:0006689=IEA, GO:0030149=NAS, GO:0005730=IDA, GO:0019377=NAS, GO:0044281=TAS, GO:0005764=NAS, GO:0030290=NAS, GO:0043231=IDA, GO:0005739=IEA, GO:0005737=IDA, GO:0007611=IEA, GO:0050885=IEA, GO:0043202=TAS} ganglioside catabolic process, glycolipid catabolic process, glycosphingolipid metabolic process, learning or memory, lipid storage, neuromuscular process controlling balance, oligosaccharide catabolic process, small molecule metabolic process, sphingolipid catabolic process, sphingolipid metabolic process cytoplasm, intracellular membrane-bounded organelle, lysosomal lumen, lysosome, mitochondrion, nucleolus beta-N-acetylhexosaminidase activity, sphingolipid activator protein activity Human GMCL1 UniProtKB UniProtKB {GO:0006355=GO_REF:0000019, GO:0007275=GO_REF:0000037, GO:0005635=GO_REF:0000019, GO:0007283=GO_REF:0000037, GO:0016363=GO_REF:0000039, GO:0030154=GO_REF:0000037} Q96IK5 Germ cell-less protein-like 1 protein 20130413 {GO:0006355=IEA, GO:0007275=IEA, GO:0005635=IEA, GO:0007283=IEA, GO:0016363=IEA, GO:0030154=IEA} cell differentiation, multicellular organismal development, regulation of transcription, DNA-dependent, spermatogenesis nuclear envelope, nuclear matrix Human UniProtKB-SubCell:SL-0181 GMDS UniProtKB UniProtKB {GO:0005622=GO_REF:0000002, GO:0050662=GO_REF:0000002, GO:0005737=PMID:9525924, GO:0007219=GO_REF:0000024, GO:0008446=PMID:9603974, GO:0019673=PMID:9603974, GO:0042351=PMID:9525924, GO:0070401=PMID:9525924} O60547 GDP-mannose 4,6 dehydratase protein 20110815 {GO:0005622=IEA, GO:0050662=IEA, GO:0005737=IC, GO:0007219=ISS, GO:0008446=IGI, GO:0019673=IGI, GO:0042351=IDA, GO:0070401=IDA} 'de novo' GDP-L-fucose biosynthetic process, GDP-mannose metabolic process, Notch signaling pathway cytoplasm, intracellular GDP-mannose 4,6-dehydratase activity, NADP+ binding, coenzyme binding Human UniProtKB:Q1LVF8 GMEB1 HPA UniProtKB {GO:0005737=GO_REF:0000039, GO:0003700=GO_REF:0000019, GO:0003713=GO_REF:0000002, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0003677=GO_REF:0000037, GO:0046872=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q9Y692 Glucocorticoid modulatory element-binding protein 1 protein 20111111 {GO:0005737=IEA, GO:0003700=IEA, GO:0003713=IEA, GO:0005730=IDA, GO:0005634=IDA, GO:0003677=IEA, GO:0046872=IEA, GO:0006351=IEA} transcription, DNA-dependent cytoplasm, nucleolus, nucleus DNA binding, metal ion binding, sequence-specific DNA binding transcription factor activity, transcription coactivator activity NOT Human GMEB2 HPA UniProtKB {GO:0006355=GO_REF:0000037, GO:0005737=GO_REF:0000052, GO:0006366=PMID:10523663, GO:0003713=GO_REF:0000002, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0003677=GO_REF:0000037, GO:0046872=GO_REF:0000037} Q9UKD1 Glucocorticoid modulatory element-binding protein 2 protein 20101115 {GO:0006355=IEA, GO:0005737=IDA, GO:0006366=TAS, GO:0003713=IEA, GO:0005730=IDA, GO:0005634=IDA, GO:0003677=IEA, GO:0046872=IEA} regulation of transcription, DNA-dependent, transcription from RNA polymerase II promoter cytoplasm, nucleolus, nucleus DNA binding, metal ion binding, transcription coactivator activity Human GMFB GOC UniProtKB {GO:0005622=GO_REF:0000002, GO:0007165=PMID:8798479, GO:0004860=PMID:8639570, GO:0006468=PMID:7598724, GO:0003779=GO_REF:0000002, GO:0006469=PMID:8639570, GO:0004871=PMID:8798479, GO:0043085=PMID:8798479, GO:0008047=PMID:8798479, GO:0008083=GO_REF:0000037, GO:0007399=PMID:1712830} P60983 Glia maturation factor beta protein 20130413 {GO:0005622=IEA, GO:0007165=TAS, GO:0004860=TAS, GO:0006468=TAS, GO:0003779=IEA, GO:0006469=TAS, GO:0004871=TAS, GO:0043085=TAS, GO:0008047=TAS, GO:0008083=IEA, GO:0007399=TAS} negative regulation of protein kinase activity, nervous system development, positive regulation of catalytic activity, protein phosphorylation, signal transduction intracellular actin binding, enzyme activator activity, growth factor activity, protein kinase inhibitor activity, signal transducer activity Human GMFG GOC UniProtKB {GO:0005622=GO_REF:0000002, GO:0004860=PMID:8639570, GO:0006468=PMID:7598724, GO:0003779=GO_REF:0000002, GO:0006469=PMID:8639570, GO:0043085=PMID:8798479, GO:0008047=PMID:8798479, GO:0008083=GO_REF:0000037} O60234 Glia maturation factor gamma protein 20130413 {GO:0005622=IEA, GO:0004860=TAS, GO:0006468=TAS, GO:0003779=IEA, GO:0006469=TAS, GO:0043085=TAS, GO:0008047=TAS, GO:0008083=IEA} negative regulation of protein kinase activity, positive regulation of catalytic activity, protein phosphorylation intracellular actin binding, enzyme activator activity, growth factor activity, protein kinase inhibitor activity Human GMIP GOC UniProtKB {GO:0005515=PMID:12093360, GO:0035556=PMID:12093360, GO:0005622=PMID:12093360, GO:0051056=Reactome:REACT_11051, GO:0032321=PMID:12093360, GO:0034259=PMID:12093360, GO:0007264=Reactome:REACT_11044, GO:0005100=PMID:12093360, GO:0046872=GO_REF:0000037, GO:0005829=Reactome:REACT_9982} Q9P107 GEM-interacting protein protein 20130413 {GO:0005515=IPI, GO:0035556=IDA, GO:0005622=IC, GO:0051056=TAS, GO:0032321=IDA, GO:0034259=IDA, GO:0007264=TAS, GO:0005100=IDA, GO:0046872=IEA, GO:0005829=TAS} intracellular signal transduction, negative regulation of Rho GTPase activity, positive regulation of Rho GTPase activity, regulation of small GTPase mediated signal transduction, small GTPase mediated signal transduction cytosol, intracellular Rho GTPase activator activity, metal ion binding, protein binding Human GMNN HPA UniProtKB {GO:0005515=PMID:21543332, GO:0042826=PMID:16924111, GO:0003714=GO_REF:0000019, GO:0005634=GO_REF:0000052, GO:0045786=PMID:9635433, GO:0005829=Reactome:REACT_1787, GO:0005737=GO_REF:0000052, GO:0006461=GO_REF:0000019, GO:0070491=GO_REF:0000019, GO:0009887=GO_REF:0000019, GO:0005654=Reactome:REACT_757, GO:0008156=PMID:9635433, GO:0000278=Reactome:REACT_152, GO:0045892=PMID:16924111} O75496 Geminin protein 20120912 {GO:0005515=IPI, GO:0042826=IPI, GO:0003714=IEA, GO:0005634=IDA, GO:0045786=IDA, GO:0005829=TAS, GO:0005737=IDA, GO:0006461=IEA, GO:0070491=IEA, GO:0009887=IEA, GO:0005654=TAS, GO:0008156=IDA, GO:0000278=TAS, GO:0045892=IDA} mitotic cell cycle, negative regulation of DNA replication, negative regulation of cell cycle, negative regulation of transcription, DNA-dependent, organ morphogenesis, protein complex assembly cytoplasm, cytosol, nucleoplasm, nucleus histone deacetylase binding, protein binding, repressing transcription factor binding, transcription corepressor activity Human GMPPA Reactome UniProtKB {GO:0009058=GO_REF:0000002, GO:0016779=GO_REF:0000002, GO:0009298=Reactome:REACT_22423, GO:0006488=Reactome:REACT_22433, GO:0005525=GO_REF:0000037, GO:0044267=Reactome:REACT_17015, GO:0004475=GO_REF:0000003, GO:0043687=Reactome:REACT_22161, GO:0018279=Reactome:REACT_22426} Q96IJ6 Mannose-1-phosphate guanyltransferase alpha protein 20130301 {GO:0009058=IEA, GO:0016779=IEA, GO:0009298=TAS, GO:0006488=TAS, GO:0005525=IEA, GO:0044267=TAS, GO:0004475=IEA, GO:0043687=TAS, GO:0018279=TAS} GDP-mannose biosynthetic process, biosynthetic process, cellular protein metabolic process, dolichol-linked oligosaccharide biosynthetic process, post-translational protein modification, protein N-linked glycosylation via asparagine GTP binding, mannose-1-phosphate guanylyltransferase activity, nucleotidyltransferase activity Human GMPPB Reactome UniProtKB {GO:0005739=GO_REF:0000019, GO:0009298=Reactome:REACT_22423, GO:0006488=Reactome:REACT_22433, GO:0005525=GO_REF:0000037, GO:0044267=Reactome:REACT_17015, GO:0004475=GO_REF:0000003, GO:0043687=Reactome:REACT_22161, GO:0018279=Reactome:REACT_22426} Q9Y5P6 Mannose-1-phosphate guanyltransferase beta protein 20130301 {GO:0005739=IEA, GO:0009298=TAS, GO:0006488=TAS, GO:0005525=IEA, GO:0044267=TAS, GO:0004475=IEA, GO:0043687=TAS, GO:0018279=TAS} GDP-mannose biosynthetic process, cellular protein metabolic process, dolichol-linked oligosaccharide biosynthetic process, post-translational protein modification, protein N-linked glycosylation via asparagine mitochondrion GTP binding, mannose-1-phosphate guanylyltransferase activity Human GMPR Reactome UniProtKB {GO:0006144=Reactome:REACT_522, GO:0009409=PMID:9813009, GO:0043101=Reactome:REACT_1923, GO:0055086=Reactome:REACT_1698, GO:0044281=Reactome:REACT_111217, GO:0003920=GO_REF:0000003, GO:0046872=GO_REF:0000037, GO:0009117=GO_REF:0000002, GO:0005829=Reactome:REACT_21383} P36959 GMP reductase 1 protein 20130213 {GO:0006144=TAS, GO:0009409=TAS, GO:0043101=TAS, GO:0055086=TAS, GO:0044281=TAS, GO:0003920=IEA, GO:0046872=IEA, GO:0009117=IEA, GO:0005829=TAS} nucleobase-containing small molecule metabolic process, nucleotide metabolic process, purine nucleobase metabolic process, purine-containing compound salvage, response to cold, small molecule metabolic process cytosol GMP reductase activity, metal ion binding Human GMPR2 Reactome UniProtKB {GO:0006144=Reactome:REACT_522, GO:0043101=Reactome:REACT_1923, GO:0016491=GO_REF:0000002, GO:0055086=Reactome:REACT_1698, GO:0044281=Reactome:REACT_111217, GO:0003920=GO_REF:0000003, GO:0003824=GO_REF:0000002, GO:0046872=GO_REF:0000037, GO:0009117=GO_REF:0000002, GO:0005829=Reactome:REACT_21383, GO:0055114=GO_REF:0000002} Q9P2T1 GMP reductase 2 protein 20130213 {GO:0006144=TAS, GO:0043101=TAS, GO:0016491=IEA, GO:0055086=TAS, GO:0044281=TAS, GO:0003920=IEA, GO:0003824=IEA, GO:0046872=IEA, GO:0009117=IEA, GO:0005829=TAS, GO:0055114=IEA} nucleobase-containing small molecule metabolic process, nucleotide metabolic process, oxidation-reduction process, purine nucleobase metabolic process, purine-containing compound salvage, small molecule metabolic process cytosol GMP reductase activity, catalytic activity, metal ion binding, oxidoreductase activity Human GMPS Reactome UniProtKB {GO:0016462=GO_REF:0000002, GO:0009168=Reactome:REACT_1776, GO:0006177=GO_REF:0000002, GO:0006144=Reactome:REACT_522, GO:0055086=Reactome:REACT_1698, GO:0009113=PMID:8089153, GO:0003922=GO_REF:0000003, GO:0044281=Reactome:REACT_111217, GO:0003921=PMID:8089153, GO:0005524=GO_REF:0000037, GO:0005829=Reactome:REACT_628, GO:0006541=GO_REF:0000037} P49915 "GMP synthase ""glutamine-hydrolyzing""" protein 20130301 {GO:0016462=IEA, GO:0009168=TAS, GO:0006177=IEA, GO:0006144=TAS, GO:0055086=TAS, GO:0009113=TAS, GO:0003922=IEA, GO:0044281=TAS, GO:0003921=TAS, GO:0005524=IEA, GO:0005829=TAS, GO:0006541=IEA} GMP biosynthetic process, glutamine metabolic process, nucleobase-containing small molecule metabolic process, purine nucleobase biosynthetic process, purine nucleobase metabolic process, purine ribonucleoside monophosphate biosynthetic process, small molecule metabolic process cytosol ATP binding, GMP synthase (glutamine-hydrolyzing) activity, GMP synthase activity, pyrophosphatase activity Human GNA11 Reactome UniProtKB {GO:0001664=GO_REF:0000033, GO:0005886=Reactome:REACT_23902, GO:0005834=GO_REF:0000033, GO:0003924=GO_REF:0000002, GO:0030168=Reactome:REACT_798, GO:0031683=GO_REF:0000033, GO:0005525=GO_REF:0000037, GO:0046872=GO_REF:0000037, GO:0031234=GO_REF:0000033, GO:0007507=GO_REF:0000019, GO:0007165=PMID:8530500, GO:0005737=PMID:9175863, GO:0001501=GO_REF:0000019, GO:0007186=GO_REF:0000002, GO:0007596=Reactome:REACT_604, GO:0060158=GO_REF:0000033, GO:0045634=GO_REF:0000019, GO:0007188=GO_REF:0000033, GO:0004871=GO_REF:0000033, GO:0001508=GO_REF:0000033, GO:0048066=GO_REF:0000019} P29992 Guanine nucleotide-binding protein subunit alpha-11 protein 20130301 {GO:0001664=IBA, GO:0005886=TAS, GO:0005834=IBA, GO:0003924=IEA, GO:0030168=TAS, GO:0031683=IBA, GO:0005525=IEA, GO:0046872=IEA, GO:0031234=IBA, GO:0007507=IEA, GO:0007165=TAS, GO:0005737=TAS, GO:0001501=IEA, GO:0007186=IEA, GO:0007596=TAS, GO:0060158=IBA, GO:0045634=IEA, GO:0007188=IBA, GO:0004871=IBA, GO:0001508=IBA, GO:0048066=IEA} G-protein coupled receptor signaling pathway, adenylate cyclase-modulating G-protein coupled receptor signaling pathway, blood coagulation, developmental pigmentation, heart development, phospholipase C-activating dopamine receptor signaling pathway, platelet activation, regulation of action potential, regulation of melanocyte differentiation, signal transduction, skeletal system development cytoplasm, extrinsic to internal side of plasma membrane, heterotrimeric G-protein complex, plasma membrane G-protein beta/gamma-subunit complex binding, G-protein coupled receptor binding, GTP binding, GTPase activity, metal ion binding, signal transducer activity Human GNA12 Reactome UniProtKB {GO:0005515=PMID:10026210, GO:0005886=Reactome:REACT_23796, GO:0007264=GO_REF:0000002, GO:0008360=GO_REF:0000019, GO:0003924=GO_REF:0000033, GO:0007266=GO_REF:0000033, GO:0031526=GO_REF:0000033, GO:0030154=GO_REF:0000019, GO:0007243=GO_REF:0000019, GO:0046872=GO_REF:0000037, GO:0004871=GO_REF:0000033, GO:0001664=GO_REF:0000002, GO:0042493=GO_REF:0000019, GO:0005834=GO_REF:0000033, GO:0030168=Reactome:REACT_798, GO:0005525=GO_REF:0000037, GO:0031683=GO_REF:0000033, GO:0001701=GO_REF:0000019, GO:0031234=GO_REF:0000033, GO:0019001=GO_REF:0000002, GO:0007186=PMID:8290554, GO:0007596=Reactome:REACT_604, GO:0031752=GO_REF:0000033, GO:0007188=GO_REF:0000033, GO:0042733=GO_REF:0000019} Q03113 Guanine nucleotide-binding protein subunit alpha-12 protein 20130213 {GO:0005515=IPI, GO:0005886=TAS, GO:0007264=IEA, GO:0008360=IEA, GO:0003924=IBA, GO:0007266=IBA, GO:0031526=IBA, GO:0030154=IEA, GO:0007243=IEA, GO:0046872=IEA, GO:0004871=IBA, GO:0001664=IEA, GO:0042493=IEA, GO:0005834=IBA, GO:0030168=TAS, GO:0005525=IEA, GO:0031683=IBA, GO:0001701=IEA, GO:0031234=IBA, GO:0019001=IEA, GO:0007186=TAS, GO:0007596=TAS, GO:0031752=IBA, GO:0007188=IBA, GO:0042733=IEA} G-protein coupled receptor signaling pathway, Rho protein signal transduction, adenylate cyclase-modulating G-protein coupled receptor signaling pathway, blood coagulation, cell differentiation, embryonic digit morphogenesis, in utero embryonic development, intracellular protein kinase cascade, platelet activation, regulation of cell shape, response to drug, small GTPase mediated signal transduction brush border membrane, extrinsic to internal side of plasma membrane, heterotrimeric G-protein complex, plasma membrane D5 dopamine receptor binding, G-protein beta/gamma-subunit complex binding, G-protein coupled receptor binding, GTP binding, GTPase activity, guanyl nucleotide binding, metal ion binding, protein binding, signal transducer activity Human GNA13 IntAct UniProtKB {GO:0005515=PMID:12681510, GO:0005886=Reactome:REACT_23796, GO:0008360=GO_REF:0000019, GO:0003924=GO_REF:0000033, GO:0006928=PMID:8999798, GO:0007266=GO_REF:0000033, GO:0031526=GO_REF:0000033, GO:0031702=GO_REF:0000033, GO:0046872=GO_REF:0000037, GO:0030154=GO_REF:0000019, GO:0007243=GO_REF:0000019, GO:0004871=GO_REF:0000033, GO:0030334=GO_REF:0000019, GO:0031584=GO_REF:0000033, GO:0042470=GO_REF:0000039, GO:0001569=GO_REF:0000019, GO:0001664=GO_REF:0000002, GO:0005834=GO_REF:0000033, GO:0030168=Reactome:REACT_798, GO:0005525=GO_REF:0000037, GO:0031683=GO_REF:0000033, GO:0001701=GO_REF:0000019, GO:0031234=GO_REF:0000033, GO:0007165=PMID:7791744, GO:0007596=Reactome:REACT_604, GO:0031752=GO_REF:0000033, GO:0007189=GO_REF:0000033} Q14344 Guanine nucleotide-binding protein subunit alpha-13 protein 20130415 {GO:0005515=IPI, GO:0005886=TAS, GO:0008360=IEA, GO:0003924=IBA, GO:0006928=TAS, GO:0007266=IBA, GO:0031526=IBA, GO:0031702=IBA, GO:0046872=IEA, GO:0030154=IEA, GO:0007243=IEA, GO:0004871=IBA, GO:0030334=IEA, GO:0031584=IBA, GO:0042470=IEA, GO:0001569=IEA, GO:0001664=IEA, GO:0005834=IBA, GO:0030168=TAS, GO:0005525=IEA, GO:0031683=IBA, GO:0001701=IEA, GO:0031234=IBA, GO:0007165=TAS, GO:0007596=TAS, GO:0031752=IBA, GO:0007189=IBA} Rho protein signal transduction, activation of phospholipase D activity, adenylate cyclase-activating G-protein coupled receptor signaling pathway, blood coagulation, cell differentiation, cellular component movement, in utero embryonic development, intracellular protein kinase cascade, patterning of blood vessels, platelet activation, regulation of cell migration, regulation of cell shape, signal transduction brush border membrane, extrinsic to internal side of plasma membrane, heterotrimeric G-protein complex, melanosome, plasma membrane D5 dopamine receptor binding, G-protein beta/gamma-subunit complex binding, G-protein coupled receptor binding, GTP binding, GTPase activity, metal ion binding, protein binding, signal transducer activity, type 1 angiotensin receptor binding Human UniProtKB:Q92888 GNA14 Reactome UniProtKB {GO:0001664=GO_REF:0000033, GO:0005886=Reactome:REACT_23902, GO:0005834=GO_REF:0000033, GO:0003924=GO_REF:0000002, GO:0030168=Reactome:REACT_798, GO:0005525=GO_REF:0000037, GO:0031683=GO_REF:0000033, GO:0046872=GO_REF:0000037, GO:0031234=GO_REF:0000033, GO:0007165=PMID:10191087, GO:0007596=Reactome:REACT_604, GO:0060158=GO_REF:0000033, GO:0007188=GO_REF:0000033, GO:0004871=GO_REF:0000033} O95837 Guanine nucleotide-binding protein subunit alpha-14 protein 20130301 {GO:0001664=IBA, GO:0005886=TAS, GO:0005834=IBA, GO:0003924=IEA, GO:0030168=TAS, GO:0005525=IEA, GO:0031683=IBA, GO:0046872=IEA, GO:0031234=IBA, GO:0007165=TAS, GO:0007596=TAS, GO:0060158=IBA, GO:0007188=IBA, GO:0004871=IBA} adenylate cyclase-modulating G-protein coupled receptor signaling pathway, blood coagulation, phospholipase C-activating dopamine receptor signaling pathway, platelet activation, signal transduction extrinsic to internal side of plasma membrane, heterotrimeric G-protein complex, plasma membrane G-protein beta/gamma-subunit complex binding, G-protein coupled receptor binding, GTP binding, GTPase activity, metal ion binding, signal transducer activity Human GNA15 Reactome UniProtKB {GO:0001664=GO_REF:0000033, GO:0005886=Reactome:REACT_23902, GO:0005834=PMID:10571060, GO:0003924=GO_REF:0000002, GO:0030168=Reactome:REACT_798, GO:0007202=PMID:7797501, GO:0031683=GO_REF:0000033, GO:0005525=GO_REF:0000029, GO:0007204=PMID:10571060, GO:0046872=GO_REF:0000037, GO:0031234=GO_REF:0000033, GO:0019001=GO_REF:0000002, GO:0007186=GO_REF:0000002, GO:0007596=Reactome:REACT_604, GO:0007207=PMID:7797501, GO:0060158=GO_REF:0000033, GO:0007188=GO_REF:0000033, GO:0004871=PMID:10571060} P30679 Guanine nucleotide-binding protein subunit alpha-15 protein 20130301 {GO:0001664=IBA, GO:0005886=TAS, GO:0005834=NAS, GO:0003924=IEA, GO:0030168=TAS, GO:0007202=TAS, GO:0031683=IBA, GO:0005525=NAS, GO:0007204=IGI, GO:0046872=IEA, GO:0031234=IBA, GO:0019001=IEA, GO:0007186=IEA, GO:0007596=TAS, GO:0007207=TAS, GO:0060158=IBA, GO:0007188=IBA, GO:0004871=IGI} G-protein coupled receptor signaling pathway, activation of phospholipase C activity, adenylate cyclase-modulating G-protein coupled receptor signaling pathway, blood coagulation, elevation of cytosolic calcium ion concentration, phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway, phospholipase C-activating dopamine receptor signaling pathway, platelet activation extrinsic to internal side of plasma membrane, heterotrimeric G-protein complex, plasma membrane G-protein beta/gamma-subunit complex binding, G-protein coupled receptor binding, GTP binding, GTPase activity, guanyl nucleotide binding, metal ion binding, signal transducer activity Human GNAI1 BHF-UCL UniProtKB {GO:0005515=PMID:15537540, GO:0005886=GO_REF:0000054, GO:0003924=Reactome:REACT_15495, GO:0043434=GO_REF:0000024, GO:0007268=Reactome:REACT_13685, GO:0005634=GO_REF:0000039, GO:0006906=GO_REF:0000019, GO:0007193=Reactome:REACT_15333, GO:0046872=GO_REF:0000037, GO:0005622=GO_REF:0000019, GO:0005737=PMID:17635935, GO:0004871=GO_REF:0000033, GO:0005813=PMID:17635935, GO:0005794=GO_REF:0000019, GO:0005834=GO_REF:0000033, GO:0030168=Reactome:REACT_798, GO:0030496=PMID:17635935, GO:0031683=GO_REF:0000033, GO:0005525=GO_REF:0000024, GO:0031234=GO_REF:0000033, GO:0042588=GO_REF:0000019, GO:0019001=GO_REF:0000002, GO:0007049=GO_REF:0000037, GO:0007186=GO_REF:0000024, GO:0007596=Reactome:REACT_604, GO:0045121=GO_REF:0000019, GO:0031821=GO_REF:0000033, GO:0007188=GO_REF:0000002, GO:0051301=PMID:17635935} P63096 Guanine nucleotide-binding protein G(i) subunit alpha-1 protein 20120510 {GO:0005515=IPI, GO:0005886=IDA, GO:0003924=TAS, GO:0043434=ISS, GO:0007268=TAS, GO:0005634=IEA, GO:0006906=IEA, GO:0007193=TAS, GO:0046872=IEA, GO:0005622=IEA, GO:0005737=IDA, GO:0004871=IBA, GO:0005813=IDA, GO:0005794=IEA, GO:0005834=IBA, GO:0030168=TAS, GO:0030496=IDA, GO:0031683=IBA, GO:0005525=ISS, GO:0031234=IBA, GO:0042588=IEA, GO:0019001=IEA, GO:0007049=IEA, GO:0007186=ISS, GO:0007596=TAS, GO:0045121=IEA, GO:0031821=IBA, GO:0007188=IEA, GO:0051301=IMP} G-protein coupled receptor signaling pathway, adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway, adenylate cyclase-modulating G-protein coupled receptor signaling pathway, blood coagulation, cell cycle, cell division, platelet activation, response to peptide hormone stimulus, synaptic transmission, vesicle fusion Golgi apparatus, centrosome, cytoplasm, extrinsic to internal side of plasma membrane, heterotrimeric G-protein complex, intracellular, membrane raft, midbody, nucleus, plasma membrane, zymogen granule G-protein beta/gamma-subunit complex binding, G-protein coupled serotonin receptor binding, GTP binding, GTPase activity, guanyl nucleotide binding, metal ion binding, protein binding, signal transducer activity Human UniProtKB:G1SEJ8 GNAI2 IntAct UniProtKB {GO:0005515=PMID:16189514, GO:0008284=GO_REF:0000019, GO:0005886=Reactome:REACT_22335, GO:0008283=GO_REF:0000019, GO:0003924=GO_REF:0000033, GO:0007268=Reactome:REACT_13685, GO:0005634=GO_REF:0000019, GO:0007194=PMID:9637720, GO:0007193=Reactome:REACT_15333, GO:0007243=GO_REF:0000019, GO:0046872=GO_REF:0000037, GO:0005829=GO_REF:0000019, GO:0005737=PMID:17635935, GO:0000186=GO_REF:0000019, GO:0051924=GO_REF:0000019, GO:0004871=GO_REF:0000033, GO:0005813=PMID:17635935, GO:0001664=GO_REF:0000033, GO:0007584=PMID:8587610, GO:0005834=GO_REF:0000033, GO:0030168=Reactome:REACT_798, GO:0030496=PMID:17635935, GO:0007214=GO_REF:0000033, GO:0005525=GO_REF:0000037, GO:0031683=GO_REF:0000033, GO:0007213=GO_REF:0000019, GO:0031234=GO_REF:0000033, GO:0007165=PMID:9637720, GO:0007049=GO_REF:0000037, GO:0019001=GO_REF:0000002, GO:0001973=GO_REF:0000033, GO:0007186=PMID:8587610, GO:0007596=Reactome:REACT_604, GO:0050805=GO_REF:0000019, GO:0007188=GO_REF:0000002, GO:0045121=GO_REF:0000019, GO:0051301=PMID:17635935} P04899 Guanine nucleotide-binding protein G(i) subunit alpha-2 protein 20130415 {GO:0005515=IPI, GO:0008284=IEA, GO:0005886=TAS, GO:0008283=IEA, GO:0003924=IBA, GO:0007268=TAS, GO:0005634=IEA, GO:0007194=TAS, GO:0007193=TAS, GO:0007243=IEA, GO:0046872=IEA, GO:0005829=IEA, GO:0005737=IDA, GO:0000186=IEA, GO:0051924=IEA, GO:0004871=IBA, GO:0005813=IDA, GO:0001664=IBA, GO:0007584=TAS, GO:0005834=IBA, GO:0030168=TAS, GO:0030496=IDA, GO:0007214=IBA, GO:0005525=IEA, GO:0031683=IBA, GO:0007213=IEA, GO:0031234=IBA, GO:0007165=TAS, GO:0007049=IEA, GO:0019001=IEA, GO:0001973=IBA, GO:0007186=TAS, GO:0007596=TAS, GO:0050805=IEA, GO:0007188=IEA, GO:0045121=IEA, GO:0051301=IMP} G-protein coupled acetylcholine receptor signaling pathway, G-protein coupled receptor signaling pathway, activation of MAPKK activity, adenosine receptor signaling pathway, adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway, adenylate cyclase-modulating G-protein coupled receptor signaling pathway, blood coagulation, cell cycle, cell division, cell proliferation, gamma-aminobutyric acid signaling pathway, intracellular protein kinase cascade, negative regulation of adenylate cyclase activity, negative regulation of synaptic transmission, platelet activation, positive regulation of cell proliferation, regulation of calcium ion transport, response to nutrient, signal transduction, synaptic transmission centrosome, cytoplasm, cytosol, extrinsic to internal side of plasma membrane, heterotrimeric G-protein complex, membrane raft, midbody, nucleus, plasma membrane G-protein beta/gamma-subunit complex binding, G-protein coupled receptor binding, GTP binding, GTPase activity, guanyl nucleotide binding, metal ion binding, protein binding, signal transducer activity Human UniProtKB:Q99750 GNAI3 Reactome UniProtKB {GO:0005813=PMID:17635935, GO:0005794=GO_REF:0000019, GO:0005886=Reactome:REACT_22335, GO:0005834=GO_REF:0000033, GO:0003924=GO_REF:0000033, GO:0030168=Reactome:REACT_798, GO:0007268=Reactome:REACT_13685, GO:0030496=PMID:17635935, GO:0007194=PMID:7608168, GO:0005525=GO_REF:0000037, GO:0031683=GO_REF:0000033, GO:0007193=Reactome:REACT_15333, GO:0006906=GO_REF:0000019, GO:0046872=GO_REF:0000037, GO:0031234=GO_REF:0000033, GO:0042588=GO_REF:0000019, GO:0005737=PMID:17635935, GO:0007049=GO_REF:0000037, GO:0007596=Reactome:REACT_604, GO:0006810=PMID:2452165, GO:0045121=GO_REF:0000019, GO:0031821=GO_REF:0000033, GO:0004871=GO_REF:0000033, GO:0051301=PMID:17635935} P08754 Guanine nucleotide-binding protein G(k) subunit alpha protein 20130301 {GO:0005813=IDA, GO:0005794=IEA, GO:0005886=TAS, GO:0005834=IBA, GO:0003924=IBA, GO:0030168=TAS, GO:0007268=TAS, GO:0030496=IDA, GO:0007194=TAS, GO:0005525=IEA, GO:0031683=IBA, GO:0007193=TAS, GO:0006906=IEA, GO:0046872=IEA, GO:0031234=IBA, GO:0042588=IEA, GO:0005737=IDA, GO:0007049=IEA, GO:0007596=TAS, GO:0006810=NAS, GO:0045121=IEA, GO:0031821=IBA, GO:0004871=IBA, GO:0051301=IDA} adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway, blood coagulation, cell cycle, cell division, negative regulation of adenylate cyclase activity, platelet activation, synaptic transmission, transport, vesicle fusion Golgi apparatus, centrosome, cytoplasm, extrinsic to internal side of plasma membrane, heterotrimeric G-protein complex, membrane raft, midbody, plasma membrane, zymogen granule G-protein beta/gamma-subunit complex binding, G-protein coupled serotonin receptor binding, GTP binding, GTPase activity, metal ion binding, signal transducer activity Human GNAL Reactome UniProtKB {GO:0007608=GO_REF:0000033, GO:0001664=GO_REF:0000033, GO:0005886=Reactome:REACT_15547, GO:0005834=GO_REF:0000033, GO:0003924=GO_REF:0000002, GO:0007268=Reactome:REACT_13685, GO:0031683=GO_REF:0000033, GO:0005525=GO_REF:0000037, GO:0007193=Reactome:REACT_15333, GO:0046872=GO_REF:0000037, GO:0031234=GO_REF:0000033, GO:0007191=GO_REF:0000033, GO:0007165=PMID:8243272, GO:0007190=GO_REF:0000019, GO:0001975=GO_REF:0000019, GO:0031000=GO_REF:0000019, GO:0007186=GO_REF:0000002, GO:0007189=Reactome:REACT_15312, GO:0004871=GO_REF:0000033} P38405 Guanine nucleotide-binding protein G(olf) subunit alpha protein 20130213 {GO:0007608=IBA, GO:0001664=IBA, GO:0005886=TAS, GO:0005834=IBA, GO:0003924=IEA, GO:0007268=TAS, GO:0031683=IBA, GO:0005525=IEA, GO:0007193=TAS, GO:0046872=IEA, GO:0031234=IBA, GO:0007191=IBA, GO:0007165=TAS, GO:0007190=IEA, GO:0001975=IEA, GO:0031000=IEA, GO:0007186=IEA, GO:0007189=TAS, GO:0004871=IBA} G-protein coupled receptor signaling pathway, activation of adenylate cyclase activity, adenylate cyclase-activating G-protein coupled receptor signaling pathway, adenylate cyclase-activating dopamine receptor signaling pathway, adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway, response to amphetamine, response to caffeine, sensory perception of smell, signal transduction, synaptic transmission extrinsic to internal side of plasma membrane, heterotrimeric G-protein complex, plasma membrane G-protein beta/gamma-subunit complex binding, G-protein coupled receptor binding, GTP binding, GTPase activity, metal ion binding, signal transducer activity Human GNAO1 Reactome UniProtKB {GO:0042542=GO_REF:0000019, GO:0043005=GO_REF:0000019, GO:0005886=Reactome:REACT_15549, GO:0031852=GO_REF:0000019, GO:0008016=GO_REF:0000019, GO:0003924=GO_REF:0000033, GO:0046872=GO_REF:0000037, GO:0031175=GO_REF:0000019, GO:0005622=GO_REF:0000019, GO:0006936=PMID:9050846, GO:0007626=GO_REF:0000019, GO:0051926=GO_REF:0000019, GO:0004871=GO_REF:0000033, GO:0034097=GO_REF:0000019, GO:0051430=GO_REF:0000019, GO:0042493=GO_REF:0000019, GO:0005834=GO_REF:0000033, GO:0007568=GO_REF:0000019, GO:0043278=GO_REF:0000019, GO:0007212=GO_REF:0000033, GO:0005525=GO_REF:0000019, GO:0031683=GO_REF:0000033, GO:0031234=GO_REF:0000033, GO:0043547=GO_REF:0000019, GO:0043234=GO_REF:0000019, GO:0016020=GO_REF:0000019, GO:0007186=GO_REF:0000002, GO:0007188=GO_REF:0000033, GO:0031821=GO_REF:0000033, GO:0030900=GO_REF:0000019} P09471 Guanine nucleotide-binding protein G(o) subunit alpha protein 20130123 {GO:0042542=IEA, GO:0043005=IEA, GO:0005886=TAS, GO:0031852=IEA, GO:0008016=IEA, GO:0003924=IBA, GO:0046872=IEA, GO:0031175=IEA, GO:0005622=IEA, GO:0006936=TAS, GO:0007626=IEA, GO:0051926=IEA, GO:0004871=IBA, GO:0034097=IEA, GO:0051430=IEA, GO:0042493=IEA, GO:0005834=IBA, GO:0007568=IEA, GO:0043278=IEA, GO:0007212=IBA, GO:0005525=IEA, GO:0031683=IBA, GO:0031234=IBA, GO:0043547=IEA, GO:0043234=IEA, GO:0016020=IEA, GO:0007186=IEA, GO:0007188=IBA, GO:0031821=IBA, GO:0030900=IEA} G-protein coupled receptor signaling pathway, adenylate cyclase-modulating G-protein coupled receptor signaling pathway, aging, dopamine receptor signaling pathway, forebrain development, locomotory behavior, muscle contraction, negative regulation of calcium ion transport, neuron projection development, positive regulation of GTPase activity, regulation of heart contraction, response to cytokine stimulus, response to drug, response to hydrogen peroxide, response to morphine extrinsic to internal side of plasma membrane, heterotrimeric G-protein complex, intracellular, membrane, neuron projection, plasma membrane, protein complex G-protein beta/gamma-subunit complex binding, G-protein coupled serotonin receptor binding, GTP binding, GTPase activity, corticotropin-releasing hormone receptor 1 binding, metal ion binding, mu-type opioid receptor binding, signal transducer activity Human GNAQ GOC UniProtKB {GO:0005515=PMID:18672896, GO:0005886=Reactome:REACT_23902, GO:0003924=GO_REF:0000002, GO:0007202=PMID:8825633, GO:0009791=GO_REF:0000019, GO:0046872=GO_REF:0000037, GO:0035412=PMID:20399743, GO:0007507=GO_REF:0000019, GO:0016322=GO_REF:0000019, GO:0005737=PMID:9175863, GO:0007610=GO_REF:0000019, GO:0045634=GO_REF:0000019, GO:0004871=GO_REF:0000033, GO:0048066=GO_REF:0000019, GO:0031965=GO_REF:0000039, GO:0001664=GO_REF:0000033, GO:0005834=GO_REF:0000033, GO:0050821=PMID:20399743, GO:0030168=Reactome:REACT_798, GO:0007215=GO_REF:0000033, GO:0005525=GO_REF:0000037, GO:0031683=GO_REF:0000033, GO:0031234=GO_REF:0000033, GO:0043547=PMID:15611106, GO:0001501=GO_REF:0000019, GO:0007186=GO_REF:0000002, GO:0016020=GO_REF:0000019, GO:0007596=Reactome:REACT_604, GO:0060158=GO_REF:0000033, GO:0006469=PMID:20399743, GO:0007189=GO_REF:0000033, GO:0001508=GO_REF:0000033, GO:0021884=GO_REF:0000019, GO:0042733=GO_REF:0000019, GO:0005096=PMID:15611106} P50148 Guanine nucleotide-binding protein G(q) subunit alpha protein 20130413 {GO:0005515=IPI, GO:0005886=TAS, GO:0003924=IEA, GO:0007202=TAS, GO:0009791=IEA, GO:0046872=IEA, GO:0035412=IMP, GO:0007507=IEA, GO:0016322=IEA, GO:0005737=TAS, GO:0007610=IEA, GO:0045634=IEA, GO:0004871=IBA, GO:0048066=IEA, GO:0031965=IEA, GO:0001664=IBA, GO:0005834=IBA, GO:0050821=IMP, GO:0030168=TAS, GO:0007215=IBA, GO:0005525=IEA, GO:0031683=IBA, GO:0031234=IBA, GO:0043547=IDA, GO:0001501=IEA, GO:0007186=IEA, GO:0016020=IEA, GO:0007596=TAS, GO:0060158=IBA, GO:0006469=IMP, GO:0007189=IBA, GO:0001508=IBA, GO:0021884=IEA, GO:0042733=IEA, GO:0005096=IDA} G-protein coupled receptor signaling pathway, activation of phospholipase C activity, adenylate cyclase-activating G-protein coupled receptor signaling pathway, behavior, blood coagulation, developmental pigmentation, embryonic digit morphogenesis, forebrain neuron development, glutamate receptor signaling pathway, heart development, negative regulation of protein kinase activity, neuron remodeling, phospholipase C-activating dopamine receptor signaling pathway, platelet activation, positive regulation of GTPase activity, post-embryonic development, protein stabilization, regulation of action potential, regulation of catenin import into nucleus, regulation of melanocyte differentiation, skeletal system development cytoplasm, extrinsic to internal side of plasma membrane, heterotrimeric G-protein complex, membrane, nuclear membrane, plasma membrane G-protein beta/gamma-subunit complex binding, G-protein coupled receptor binding, GTP binding, GTPase activator activity, GTPase activity, metal ion binding, protein binding, signal transducer activity Human GNAS BHF-UCL UniProtKB {GO:0007608=PMID:3018580, GO:0009306=PMID:10729789, GO:0051216=GO_REF:0000019, GO:0007606=GO_REF:0000033, GO:0031224=PMID:7997272, GO:0048701=GO_REF:0000019, GO:0001894=GO_REF:0000019, GO:0007610=GO_REF:0000019, GO:0006833=Reactome:REACT_24023, GO:0007565=PMID:10729789, GO:0031683=GO_REF:0000033, GO:0031234=GO_REF:0000033, GO:0001958=GO_REF:0000019, GO:0007186=GO_REF:0000002, GO:0071870=GO_REF:0000024, GO:0043588=GO_REF:0000019, GO:0030133=GO_REF:0000039, GO:0005886=GO_REF:0000039, GO:0031852=GO_REF:0000033, GO:0003924=GO_REF:0000033, GO:0044281=Reactome:REACT_111217, GO:0071380=GO_REF:0000024, GO:0046872=GO_REF:0000037, GO:0030425=GO_REF:0000019, GO:0005829=GO_REF:0000024, GO:0007191=GO_REF:0000033, GO:0007190=PMID:9159128, GO:0003674=GO_REF:0000015, GO:0005737=GO_REF:0000054, GO:0035264=GO_REF:0000019, GO:0071377=Reactome:REACT_1665, GO:0071514=GO_REF:0000019, GO:0006171=Reactome:REACT_18321, GO:0004871=GO_REF:0000033, GO:0042493=GO_REF:0000019, GO:0005834=GO_REF:0000033, GO:0045672=GO_REF:0000019, GO:0046907=PMID:7997272, GO:0005576=GO_REF:0000029, GO:0005525=GO_REF:0000037, GO:0055085=Reactome:REACT_15518, GO:0001726=GO_REF:0000039, GO:0032588=PMID:7997272, GO:0006306=GO_REF:0000019, GO:0040032=GO_REF:0000019, GO:0045669=GO_REF:0000019, GO:0019001=GO_REF:0000002, GO:0006112=GO_REF:0000019, GO:0004016=Reactome:REACT_18321, GO:0016020=GO_REF:0000024, GO:0035255=GO_REF:0000033, GO:0050796=Reactome:REACT_18325, GO:0007596=Reactome:REACT_604, GO:0035116=GO_REF:0000019} Q5JWF2 Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas protein 20120323 {GO:0007608=TAS, GO:0009306=NAS, GO:0051216=IEA, GO:0007606=IBA, GO:0031224=IDA, GO:0048701=IEA, GO:0001894=IEA, GO:0007610=IEA, GO:0006833=TAS, GO:0007565=NAS, GO:0031683=IBA, GO:0031234=IBA, GO:0001958=IEA, GO:0007186=IEA, GO:0071870=ISS, GO:0043588=IEA, GO:0030133=IEA, GO:0005886=IEA, GO:0031852=IBA, GO:0003924=IBA, GO:0044281=TAS, GO:0071380=ISS, GO:0046872=IEA, GO:0030425=IEA, GO:0005829=ISS, GO:0007191=IBA, GO:0007190=TAS, GO:0003674=ND, GO:0005737=IDA, GO:0035264=IEA, GO:0071377=TAS, GO:0071514=IEA, GO:0006171=TAS, GO:0004871=IBA, GO:0042493=IEA, GO:0005834=IBA, GO:0045672=IEA, GO:0046907=NAS, GO:0005576=NAS, GO:0005525=IEA, GO:0055085=TAS, GO:0001726=IEA, GO:0032588=IDA, GO:0006306=IEA, GO:0040032=IEA, GO:0045669=IEA, GO:0019001=IEA, GO:0006112=IEA, GO:0004016=TAS, GO:0016020=ISS, GO:0035255=IBA, GO:0050796=TAS, GO:0007596=TAS, GO:0035116=IEA} DNA methylation, G-protein coupled receptor signaling pathway, activation of adenylate cyclase activity, adenylate cyclase-activating dopamine receptor signaling pathway, behavior, blood coagulation, cAMP biosynthetic process, cartilage development, cellular response to catecholamine stimulus, cellular response to glucagon stimulus, cellular response to prostaglandin E stimulus, embryonic cranial skeleton morphogenesis, embryonic hindlimb morphogenesis, endochondral ossification, energy reserve metabolic process, female pregnancy, genetic imprinting, intracellular transport, multicellular organism growth, positive regulation of osteoblast differentiation, positive regulation of osteoclast differentiation, post-embryonic body morphogenesis, protein secretion, regulation of insulin secretion, response to drug, sensory perception of chemical stimulus, sensory perception of smell, skin development, small molecule metabolic process, tissue homeostasis, transmembrane transport, water transport cytoplasm, cytosol, dendrite, extracellular region, extrinsic to internal side of plasma membrane, heterotrimeric G-protein complex, intrinsic to membrane, membrane, plasma membrane, ruffle, trans-Golgi network membrane, transport vesicle G-protein beta/gamma-subunit complex binding, GTP binding, GTPase activity, adenylate cyclase activity, guanyl nucleotide binding, ionotropic glutamate receptor binding, metal ion binding, molecular_function, mu-type opioid receptor binding, signal transducer activity Human UniProtKB:P63095 GNAT1 Reactome UniProtKB {GO:0000035=GO_REF:0000024, GO:0005886=Reactome:REACT_18400, GO:0007603=PMID:17584859, GO:0060041=GO_REF:0000019, GO:0042622=GO_REF:0000024, GO:0008283=GO_REF:0000019, GO:0003924=PMID:17584859, GO:0009642=GO_REF:0000019, GO:0046872=GO_REF:0000037, GO:0016324=GO_REF:0000019, GO:0005737=GO_REF:0000019, GO:0071257=GO_REF:0000019, GO:0050908=PMID:17584859, GO:0043025=GO_REF:0000019, GO:0009416=GO_REF:0000024, GO:0004871=GO_REF:0000033, GO:0001580=GO_REF:0000033, GO:0016056=GO_REF:0000019, GO:0001664=GO_REF:0000033, GO:0019901=GO_REF:0000024, GO:0051343=GO_REF:0000019, GO:0051344=GO_REF:0000024, GO:0005834=GO_REF:0000033, GO:0031683=GO_REF:0000033, GO:0005525=GO_REF:0000024, GO:0050917=GO_REF:0000033, GO:0031234=GO_REF:0000033, GO:0007165=PMID:8673138, GO:0001917=PMID:2534964, GO:0016020=PMID:7822269, GO:0032391=GO_REF:0000019, GO:0007188=GO_REF:0000033, GO:0019003=GO_REF:0000024, GO:0007601=PMID:8673138, GO:0042462=GO_REF:0000019, GO:0001750=PMID:2534964} P11488 Guanine nucleotide-binding protein G(t) subunit alpha-1 protein 20130213 {GO:0000035=ISS, GO:0005886=TAS, GO:0007603=IMP, GO:0060041=IEA, GO:0042622=ISS, GO:0008283=IEA, GO:0003924=NAS, GO:0009642=IEA, GO:0046872=IEA, GO:0016324=IEA, GO:0005737=IEA, GO:0071257=IEA, GO:0050908=IMP, GO:0043025=IEA, GO:0009416=ISS, GO:0004871=IBA, GO:0001580=IBA, GO:0016056=IEA, GO:0001664=IBA, GO:0019901=ISS, GO:0051343=IEA, GO:0051344=ISS, GO:0005834=IBA, GO:0031683=IBA, GO:0005525=ISS, GO:0050917=IBA, GO:0031234=IBA, GO:0007165=NAS, GO:0001917=IDA, GO:0016020=NAS, GO:0032391=IEA, GO:0007188=IBA, GO:0019003=ISS, GO:0007601=TAS, GO:0042462=IEA, GO:0001750=IDA} adenylate cyclase-modulating G-protein coupled receptor signaling pathway, cell proliferation, cellular response to electrical stimulus, detection of chemical stimulus involved in sensory perception of bitter taste, detection of light stimulus involved in visual perception, eye photoreceptor cell development, negative regulation of cyclic-nucleotide phosphodiesterase activity, phototransduction, visible light, positive regulation of cyclic-nucleotide phosphodiesterase activity, response to light intensity, response to light stimulus, retina development in camera-type eye, rhodopsin mediated signaling pathway, sensory perception of umami taste, signal transduction, visual perception apical plasma membrane, cytoplasm, extrinsic to internal side of plasma membrane, heterotrimeric G-protein complex, membrane, neuronal cell body, photoreceptor connecting cilium, photoreceptor inner segment, photoreceptor outer segment, photoreceptor outer segment membrane, plasma membrane G-protein beta/gamma-subunit complex binding, G-protein coupled receptor binding, GDP binding, GTP binding, GTPase activity, acyl binding, metal ion binding, protein kinase binding, signal transducer activity Human GNAT2 Reactome UniProtKB {GO:0001664=GO_REF:0000033, GO:0005886=Reactome:REACT_18400, GO:0046549=GO_REF:0000019, GO:0042622=GO_REF:0000024, GO:0005834=GO_REF:0000033, GO:0003924=GO_REF:0000033, GO:0031683=GO_REF:0000033, GO:0009642=GO_REF:0000019, GO:0005525=PMID:1936270, GO:0007204=GO_REF:0000019, GO:0046872=GO_REF:0000037, GO:0008020=PMID:2534964, GO:0031234=GO_REF:0000033, GO:0001917=PMID:2534964, GO:0007186=PMID:2534964, GO:0050908=PMID:12077706, GO:0007188=GO_REF:0000033, GO:0004871=GO_REF:0000033, GO:0007602=PMID:2534964, GO:0007601=PMID:2534964, GO:0001580=GO_REF:0000033, GO:0001750=GO_REF:0000024} P19087 Guanine nucleotide-binding protein G(t) subunit alpha-2 protein 20130213 {GO:0001664=IBA, GO:0005886=TAS, GO:0046549=IEA, GO:0042622=ISS, GO:0005834=IBA, GO:0003924=IBA, GO:0031683=IBA, GO:0009642=IEA, GO:0005525=NAS, GO:0007204=IEA, GO:0046872=IEA, GO:0008020=NAS, GO:0031234=IBA, GO:0001917=IDA, GO:0007186=NAS, GO:0050908=IMP, GO:0007188=IBA, GO:0004871=IBA, GO:0007602=NAS, GO:0007601=NAS, GO:0001580=IBA, GO:0001750=ISS} G-protein coupled receptor signaling pathway, adenylate cyclase-modulating G-protein coupled receptor signaling pathway, detection of chemical stimulus involved in sensory perception of bitter taste, detection of light stimulus involved in visual perception, elevation of cytosolic calcium ion concentration, phototransduction, response to light intensity, retinal cone cell development, visual perception extrinsic to internal side of plasma membrane, heterotrimeric G-protein complex, photoreceptor inner segment, photoreceptor outer segment, photoreceptor outer segment membrane, plasma membrane G-protein beta/gamma-subunit complex binding, G-protein coupled photoreceptor activity, G-protein coupled receptor binding, GTP binding, GTPase activity, metal ion binding, signal transducer activity Human GNAT3 Reactome UniProtKB {GO:0001664=GO_REF:0000033, GO:0005886=Reactome:REACT_15549, GO:0005834=GO_REF:0000033, GO:0003924=GO_REF:0000033, GO:0031683=GO_REF:0000033, GO:0005525=GO_REF:0000019, GO:0050916=GO_REF:0000033, GO:0050917=GO_REF:0000033, GO:0046872=GO_REF:0000037, GO:0031234=GO_REF:0000033, GO:0043234=PMID:18468998, GO:0001917=GO_REF:0000033, GO:0016324=GO_REF:0000019, GO:0005737=GO_REF:0000039, GO:0007188=GO_REF:0000033, GO:0004871=GO_REF:0000033, GO:0001580=GO_REF:0000033, GO:0035094=GO_REF:0000019, GO:0001750=GO_REF:0000033} A8MTJ3 Guanine nucleotide-binding protein G(t) subunit alpha-3 protein 20081107 {GO:0001664=IBA, GO:0005886=TAS, GO:0005834=IBA, GO:0003924=IBA, GO:0031683=IBA, GO:0005525=IEA, GO:0050916=IBA, GO:0050917=IBA, GO:0046872=IEA, GO:0031234=IBA, GO:0043234=IDA, GO:0001917=IBA, GO:0016324=IEA, GO:0005737=IEA, GO:0007188=IBA, GO:0004871=IBA, GO:0001580=IBA, GO:0035094=IEA, GO:0001750=IBA} adenylate cyclase-modulating G-protein coupled receptor signaling pathway, detection of chemical stimulus involved in sensory perception of bitter taste, response to nicotine, sensory perception of sweet taste, sensory perception of umami taste apical plasma membrane, cytoplasm, extrinsic to internal side of plasma membrane, heterotrimeric G-protein complex, photoreceptor inner segment, photoreceptor outer segment, plasma membrane, protein complex G-protein beta/gamma-subunit complex binding, G-protein coupled receptor binding, GTP binding, GTPase activity, metal ion binding, signal transducer activity Human GNAZ Reactome UniProtKB {GO:0005886=Reactome:REACT_22380, GO:0005783=PMID:2117645, GO:0005834=GO_REF:0000033, GO:0003924=GO_REF:0000033, GO:0005635=PMID:2117645, GO:0005525=GO_REF:0000037, GO:0031683=GO_REF:0000033, GO:0007193=GO_REF:0000019, GO:0046872=GO_REF:0000037, GO:0005829=GO_REF:0000019, GO:0031234=GO_REF:0000033, GO:0007186=PMID:3129724, GO:0007188=GO_REF:0000033, GO:0031821=GO_REF:0000033, GO:0004871=GO_REF:0000033, GO:0005057=PMID:2456569} P19086 Guanine nucleotide-binding protein G(z) subunit alpha protein 20130213 {GO:0005886=TAS, GO:0005783=TAS, GO:0005834=IBA, GO:0003924=IBA, GO:0005635=TAS, GO:0005525=IEA, GO:0031683=IBA, GO:0007193=IEA, GO:0046872=IEA, GO:0005829=IEA, GO:0031234=IBA, GO:0007186=TAS, GO:0007188=IBA, GO:0031821=IBA, GO:0004871=IBA, GO:0005057=TAS} G-protein coupled receptor signaling pathway, adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway, adenylate cyclase-modulating G-protein coupled receptor signaling pathway cytosol, endoplasmic reticulum, extrinsic to internal side of plasma membrane, heterotrimeric G-protein complex, nuclear envelope, plasma membrane G-protein beta/gamma-subunit complex binding, G-protein coupled serotonin receptor binding, GTP binding, GTPase activity, metal ion binding, receptor signaling protein activity, signal transducer activity Human GNB1 GOC UniProtKB {GO:0060041=GO_REF:0000019, GO:0005886=Reactome:REACT_25066, GO:0042622=GO_REF:0000019, GO:0008283=GO_REF:0000019, GO:0003924=PMID:1543505, GO:0007200=GO_REF:0000019, GO:0007268=Reactome:REACT_13685, GO:0007265=PMID:8717044, GO:0044281=Reactome:REACT_111217, GO:0071380=GO_REF:0000024, GO:0007204=GO_REF:0000019, GO:0030425=GO_REF:0000019, GO:0007191=GO_REF:0000024, GO:0005622=GO_REF:0000024, GO:0050909=GO_REF:0000019, GO:0071377=Reactome:REACT_1665, GO:0004871=GO_REF:0000037, GO:0005834=PMID:1543505, GO:0071456=GO_REF:0000019, GO:0030168=Reactome:REACT_798, GO:0007213=PMID:8717044, GO:0044297=GO_REF:0000019, GO:0006184=PMID:3095147, GO:0001917=GO_REF:0000019, GO:0007165=PMID:8717044, GO:0051020=PMID:19255495, GO:0006112=Reactome:REACT_1505, GO:0016020=GO_REF:0000024, GO:0007596=Reactome:REACT_604, GO:0071870=GO_REF:0000024, GO:0010659=GO_REF:0000019} P62873 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 protein 20130413 {GO:0060041=IEA, GO:0005886=TAS, GO:0042622=IEA, GO:0008283=IEA, GO:0003924=IDA, GO:0007200=IEA, GO:0007268=TAS, GO:0007265=TAS, GO:0044281=TAS, GO:0071380=ISS, GO:0007204=IEA, GO:0030425=IEA, GO:0007191=ISS, GO:0005622=ISS, GO:0050909=IEA, GO:0071377=TAS, GO:0004871=IEA, GO:0005834=IDA, GO:0071456=IEA, GO:0030168=TAS, GO:0007213=TAS, GO:0044297=IEA, GO:0006184=TAS, GO:0001917=IEA, GO:0007165=TAS, GO:0051020=IPI, GO:0006112=TAS, GO:0016020=ISS, GO:0007596=TAS, GO:0071870=ISS, GO:0010659=IEA} G-protein coupled acetylcholine receptor signaling pathway, GTP catabolic process, Ras protein signal transduction, adenylate cyclase-activating dopamine receptor signaling pathway, blood coagulation, cardiac muscle cell apoptotic process, cell proliferation, cellular response to catecholamine stimulus, cellular response to glucagon stimulus, cellular response to hypoxia, cellular response to prostaglandin E stimulus, elevation of cytosolic calcium ion concentration, energy reserve metabolic process, phospholipase C-activating G-protein coupled receptor signaling pathway, platelet activation, retina development in camera-type eye, sensory perception of taste, signal transduction, small molecule metabolic process, synaptic transmission cell body, dendrite, heterotrimeric G-protein complex, intracellular, membrane, photoreceptor inner segment, photoreceptor outer segment membrane, plasma membrane GTPase activity, GTPase binding, signal transducer activity Human GNB1L UniProtKB UniProtKB {GO:0035556=PMID:11072084, GO:0003674=GO_REF:0000015, GO:0005737=GO_REF:0000019, GO:0007186=PMID:11072084, GO:0035176=GO_REF:0000019, GO:0009898=PMID:11072084} Q9BYB4 Guanine nucleotide-binding protein subunit beta-like protein 1 protein 20030805 {GO:0035556=NAS, GO:0003674=ND, GO:0005737=IEA, GO:0007186=NAS, GO:0035176=IEA, GO:0009898=NAS} G-protein coupled receptor signaling pathway, intracellular signal transduction, social behavior cytoplasm, internal side of plasma membrane molecular_function Human GNB2 GOC UniProtKB {GO:0005515=PMID:16498633, GO:0048471=PMID:16498633, GO:0005886=Reactome:REACT_25066, GO:0005246=GO_REF:0000019, GO:0003924=PMID:2902634, GO:0007268=Reactome:REACT_13685, GO:0044281=Reactome:REACT_111217, GO:0044297=GO_REF:0000019, GO:0006184=PMID:2902634, GO:0043234=GO_REF:0000019, GO:0051020=PMID:19255495, GO:0006112=Reactome:REACT_1505, GO:0007186=PMID:7649993, GO:0071377=Reactome:REACT_1665, GO:0004871=GO_REF:0000037} P62879 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 protein 20130413 {GO:0005515=IPI, GO:0048471=IDA, GO:0005886=TAS, GO:0005246=IEA, GO:0003924=TAS, GO:0007268=TAS, GO:0044281=TAS, GO:0044297=IEA, GO:0006184=TAS, GO:0043234=IEA, GO:0051020=IPI, GO:0006112=TAS, GO:0007186=TAS, GO:0071377=TAS, GO:0004871=IEA} G-protein coupled receptor signaling pathway, GTP catabolic process, cellular response to glucagon stimulus, energy reserve metabolic process, small molecule metabolic process, synaptic transmission cell body, perinuclear region of cytoplasm, plasma membrane, protein complex GTPase activity, GTPase binding, calcium channel regulator activity, protein binding, signal transducer activity Human GNB2L1 GOC UniProtKB {GO:0017148=GO_REF:0000024, GO:0005515=PMID:21146485, GO:0030308=PMID:9584165, GO:0048471=PMID:11279199, GO:0007369=GO_REF:0000037, GO:0061099=PMID:9584165, GO:0030178=GO_REF:0000024, GO:0032436=PMID:19785988, GO:0015935=GO_REF:0000024, GO:0005634=PMID:17108144, GO:0030425=GO_REF:0000024, GO:0032880=GO_REF:0000024, GO:0050765=PMID:21347310, GO:0005737=PMID:19785988, GO:0005080=PMID:11279199, GO:0043025=GO_REF:0000024, GO:0051726=PMID:9584165, GO:0043204=GO_REF:0000039, GO:0005856=GO_REF:0000039, GO:0008200=GO_REF:0000024, GO:0042169=PMID:11279199, GO:0032464=PMID:20541605, GO:0030971=PMID:9584165, GO:0030335=PMID:20499158, GO:0043065=PMID:20541605, GO:0019903=PMID:11278757, GO:2000543=GO_REF:0000024, GO:2000114=GO_REF:0000024, GO:0005102=PMID:12809483, GO:0030292=PMID:9584165, GO:0030496=PMID:15166316, GO:0001891=PMID:21347310, GO:0043547=PMID:20499158, GO:0007049=GO_REF:0000037, GO:0019048=GO_REF:0000037, GO:0001934=PMID:17108144, GO:0048511=GO_REF:0000037, GO:0051302=GO_REF:0000024, GO:0090003=GO_REF:0000019} P63244 Guanine nucleotide-binding protein subunit beta-2-like 1 protein 20130413 {GO:0017148=ISS, GO:0005515=IPI, GO:0030308=IDA, GO:0048471=IDA, GO:0007369=IEA, GO:0061099=IDA, GO:0030178=ISS, GO:0032436=IDA, GO:0015935=ISS, GO:0005634=IDA, GO:0030425=ISS, GO:0032880=ISS, GO:0050765=IMP, GO:0005737=IDA, GO:0005080=IDA, GO:0043025=ISS, GO:0051726=IDA, GO:0043204=IEA, GO:0005856=IEA, GO:0008200=ISS, GO:0042169=IDA, GO:0032464=IDA, GO:0030971=IDA, GO:0030335=IDA, GO:0043065=IDA, GO:0019903=IPI, GO:2000543=ISS, GO:2000114=ISS, GO:0005102=NAS, GO:0030292=IDA, GO:0030496=IDA, GO:0001891=IDA, GO:0043547=IDA, GO:0007049=IEA, GO:0019048=IEA, GO:0001934=IDA, GO:0048511=IEA, GO:0051302=ISS, GO:0090003=IEA} cell cycle, gastrulation, negative regulation of Wnt receptor signaling pathway, negative regulation of cell growth, negative regulation of phagocytosis, negative regulation of protein tyrosine kinase activity, negative regulation of translation, positive regulation of GTPase activity, positive regulation of apoptotic process, positive regulation of cell migration, positive regulation of gastrulation, positive regulation of proteasomal ubiquitin-dependent protein catabolic process, positive regulation of protein homooligomerization, positive regulation of protein phosphorylation, regulation of cell cycle, regulation of cell division, regulation of establishment of cell polarity, regulation of establishment of protein localization to plasma membrane, regulation of protein localization, rhythmic process, virus-host interaction cytoplasm, cytoskeleton, dendrite, midbody, neuronal cell body, nucleus, perikaryon, perinuclear region of cytoplasm, phagocytic cup, small ribosomal subunit SH2 domain binding, ion channel inhibitor activity, protein binding, protein kinase C binding, protein phosphatase binding, protein tyrosine kinase inhibitor activity, receptor binding, receptor tyrosine kinase binding Human GNB3 GOC UniProtKB {GO:0043005=GO_REF:0000019, GO:0005886=Reactome:REACT_25066, GO:0003924=PMID:9425898, GO:0007268=Reactome:REACT_13685, GO:0044281=Reactome:REACT_111217, GO:0044297=GO_REF:0000019, GO:0006184=PMID:9425898, GO:0051020=PMID:19255495, GO:0006112=Reactome:REACT_1505, GO:0007186=PMID:2107550, GO:0071377=Reactome:REACT_1665, GO:0008217=PMID:9425898, GO:0004871=GO_REF:0000037} P16520 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3 protein 20130413 {GO:0043005=IEA, GO:0005886=TAS, GO:0003924=TAS, GO:0007268=TAS, GO:0044281=TAS, GO:0044297=IEA, GO:0006184=TAS, GO:0051020=IPI, GO:0006112=TAS, GO:0007186=TAS, GO:0071377=TAS, GO:0008217=TAS, GO:0004871=IEA} G-protein coupled receptor signaling pathway, GTP catabolic process, cellular response to glucagon stimulus, energy reserve metabolic process, regulation of blood pressure, small molecule metabolic process, synaptic transmission cell body, neuron projection, plasma membrane GTPase activity, GTPase binding, signal transducer activity Human GNB4 Reactome UniProtKB {GO:0006112=Reactome:REACT_1505, GO:0005886=Reactome:REACT_22110, GO:0071377=Reactome:REACT_1665, GO:0044281=Reactome:REACT_111217, GO:0004871=GO_REF:0000037} Q9HAV0 Guanine nucleotide-binding protein subunit beta-4 protein 20130301 {GO:0006112=TAS, GO:0005886=TAS, GO:0071377=TAS, GO:0044281=TAS, GO:0004871=IEA} cellular response to glucagon stimulus, energy reserve metabolic process, small molecule metabolic process plasma membrane signal transducer activity Human GNB5 GOC UniProtKB {GO:0006184=PMID:9606987, GO:0007165=PMID:9606987, GO:0007186=GO_REF:0000019, GO:0005886=GO_REF:0000019, GO:0005834=GO_REF:0000029, GO:0003924=PMID:9606987, GO:0005634=GO_REF:0000019, GO:0004871=PMID:9606987} O14775 Guanine nucleotide-binding protein subunit beta-5 protein 20130413 {GO:0006184=NAS, GO:0007165=NAS, GO:0007186=IEA, GO:0005886=IEA, GO:0005834=NAS, GO:0003924=NAS, GO:0005634=IEA, GO:0004871=NAS} G-protein coupled receptor signaling pathway, GTP catabolic process, signal transduction heterotrimeric G-protein complex, nucleus, plasma membrane GTPase activity, signal transducer activity Human GNE PINC UniProtKB {GO:0008761=GO_REF:0000002, GO:0006054=PMID:9305888, GO:0006045=GO_REF:0000041, GO:0006047=GO_REF:0000002, GO:0005524=GO_REF:0000037, GO:0046872=GO_REF:0000037, GO:0005829=GO_REF:0000019, GO:0005737=PMID:9305888, GO:0046380=GO_REF:0000002, GO:0016787=GO_REF:0000037, GO:0009384=GO_REF:0000003, GO:0007155=PMID:10334995, GO:0009103=GO_REF:0000002} Q9Y223 Bifunctional UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase protein 20030904 {GO:0008761=IEA, GO:0006054=TAS, GO:0006045=IEA, GO:0006047=IEA, GO:0005524=IEA, GO:0046872=IEA, GO:0005829=IEA, GO:0005737=TAS, GO:0046380=IEA, GO:0016787=IEA, GO:0009384=IEA, GO:0007155=TAS, GO:0009103=IEA} N-acetylglucosamine biosynthetic process, N-acetylneuraminate biosynthetic process, N-acetylneuraminate metabolic process, UDP-N-acetylglucosamine metabolic process, cell adhesion, lipopolysaccharide biosynthetic process cytoplasm, cytosol ATP binding, N-acylmannosamine kinase activity, UDP-N-acetylglucosamine 2-epimerase activity, hydrolase activity, metal ion binding Human GNG10 GOC UniProtKB {GO:0006184=PMID:7665596, GO:0007165=PMID:7665596, GO:0006112=Reactome:REACT_1505, GO:0005886=Reactome:REACT_25066, GO:0007186=GO_REF:0000002, GO:0071377=Reactome:REACT_1665, GO:0005834=GO_REF:0000002, GO:0003924=PMID:7665596, GO:0007268=Reactome:REACT_13685, GO:0044281=Reactome:REACT_111217, GO:0004871=GO_REF:0000037} P50151 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10 protein 20130413 {GO:0006184=TAS, GO:0007165=TAS, GO:0006112=TAS, GO:0005886=TAS, GO:0007186=IEA, GO:0071377=TAS, GO:0005834=IEA, GO:0003924=TAS, GO:0007268=TAS, GO:0044281=TAS, GO:0004871=IEA} G-protein coupled receptor signaling pathway, GTP catabolic process, cellular response to glucagon stimulus, energy reserve metabolic process, signal transduction, small molecule metabolic process, synaptic transmission heterotrimeric G-protein complex, plasma membrane GTPase activity, signal transducer activity Human GNG11 GOC UniProtKB {GO:0006184=PMID:7665596, GO:0007165=PMID:7665596, GO:0006112=Reactome:REACT_1505, GO:0005886=Reactome:REACT_22110, GO:0007186=GO_REF:0000002, GO:0071377=Reactome:REACT_1665, GO:0005834=GO_REF:0000002, GO:0003924=PMID:7665596, GO:0044281=Reactome:REACT_111217, GO:0004871=GO_REF:0000037} P61952 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11 protein 20130413 {GO:0006184=TAS, GO:0007165=TAS, GO:0006112=TAS, GO:0005886=TAS, GO:0007186=IEA, GO:0071377=TAS, GO:0005834=IEA, GO:0003924=TAS, GO:0044281=TAS, GO:0004871=IEA} G-protein coupled receptor signaling pathway, GTP catabolic process, cellular response to glucagon stimulus, energy reserve metabolic process, signal transduction, small molecule metabolic process heterotrimeric G-protein complex, plasma membrane GTPase activity, signal transducer activity Human GNG12 Reactome UniProtKB {GO:0007165=PMID:10819326, GO:0006112=Reactome:REACT_1505, GO:0005886=Reactome:REACT_25066, GO:0007186=GO_REF:0000002, GO:0071377=Reactome:REACT_1665, GO:0005834=GO_REF:0000002, GO:0007268=Reactome:REACT_13685, GO:0044281=Reactome:REACT_111217, GO:0004871=GO_REF:0000037} Q9UBI6 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12 protein 20130301 {GO:0007165=TAS, GO:0006112=TAS, GO:0005886=TAS, GO:0007186=IEA, GO:0071377=TAS, GO:0005834=IEA, GO:0007268=TAS, GO:0044281=TAS, GO:0004871=IEA} G-protein coupled receptor signaling pathway, cellular response to glucagon stimulus, energy reserve metabolic process, signal transduction, small molecule metabolic process, synaptic transmission heterotrimeric G-protein complex, plasma membrane signal transducer activity Human GNG13 Reactome UniProtKB {GO:0006112=Reactome:REACT_1505, GO:0005886=Reactome:REACT_22110, GO:0050909=GO_REF:0000019, GO:0071377=Reactome:REACT_1665, GO:0005834=GO_REF:0000019, GO:0007200=GO_REF:0000019, GO:0044281=Reactome:REACT_111217, GO:0004871=GO_REF:0000037} Q9P2W3 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13 protein 20130301 {GO:0006112=TAS, GO:0005886=TAS, GO:0050909=IEA, GO:0071377=TAS, GO:0005834=IEA, GO:0007200=IEA, GO:0044281=TAS, GO:0004871=IEA} cellular response to glucagon stimulus, energy reserve metabolic process, phospholipase C-activating G-protein coupled receptor signaling pathway, sensory perception of taste, small molecule metabolic process heterotrimeric G-protein complex, plasma membrane signal transducer activity Human GNG2 BHF-UCL UniProtKB {GO:0005886=Reactome:REACT_25066, GO:0008283=GO_REF:0000019, GO:0005834=GO_REF:0000024, GO:0007268=Reactome:REACT_13685, GO:0030168=Reactome:REACT_798, GO:0044281=Reactome:REACT_111217, GO:0071380=GO_REF:0000024, GO:0007191=GO_REF:0000024, GO:0006112=Reactome:REACT_1505, GO:0016020=GO_REF:0000024, GO:0007186=GO_REF:0000002, GO:0007596=Reactome:REACT_604, GO:0071377=Reactome:REACT_1665, GO:0071870=GO_REF:0000024, GO:0004871=GO_REF:0000037} P59768 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 protein 20120329 {GO:0005886=TAS, GO:0008283=IEA, GO:0005834=ISS, GO:0007268=TAS, GO:0030168=TAS, GO:0044281=TAS, GO:0071380=ISS, GO:0007191=ISS, GO:0006112=TAS, GO:0016020=ISS, GO:0007186=IEA, GO:0007596=TAS, GO:0071377=TAS, GO:0071870=ISS, GO:0004871=IEA} G-protein coupled receptor signaling pathway, adenylate cyclase-activating dopamine receptor signaling pathway, blood coagulation, cell proliferation, cellular response to catecholamine stimulus, cellular response to glucagon stimulus, cellular response to prostaglandin E stimulus, energy reserve metabolic process, platelet activation, small molecule metabolic process, synaptic transmission heterotrimeric G-protein complex, membrane, plasma membrane signal transducer activity Human UniProtKB:P63212 GNG3 GOC UniProtKB {GO:0006184=PMID:10075696, GO:0000187=PMID:10075696, GO:0006112=Reactome:REACT_1505, GO:0005886=Reactome:REACT_25066, GO:0007186=GO_REF:0000002, GO:0071377=Reactome:REACT_1665, GO:0005834=GO_REF:0000002, GO:0003924=PMID:10075696, GO:0007268=Reactome:REACT_13685, GO:0044281=Reactome:REACT_111217, GO:0004871=GO_REF:0000037} P63215 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3 protein 20130413 {GO:0006184=TAS, GO:0000187=TAS, GO:0006112=TAS, GO:0005886=TAS, GO:0007186=IEA, GO:0071377=TAS, GO:0005834=IEA, GO:0003924=TAS, GO:0007268=TAS, GO:0044281=TAS, GO:0004871=IEA} G-protein coupled receptor signaling pathway, GTP catabolic process, activation of MAPK activity, cellular response to glucagon stimulus, energy reserve metabolic process, small molecule metabolic process, synaptic transmission heterotrimeric G-protein complex, plasma membrane GTPase activity, signal transducer activity Human GNG4 IntAct UniProtKB {GO:0005515=PMID:23021213, GO:0030308=PMID:15824735, GO:0006112=Reactome:REACT_1505, GO:0008277=PMID:7665596, GO:0005886=Reactome:REACT_25066, GO:0007186=GO_REF:0000002, GO:0071377=Reactome:REACT_1665, GO:0005834=GO_REF:0000002, GO:0007268=Reactome:REACT_13685, GO:0044281=Reactome:REACT_111217, GO:0004871=GO_REF:0000037} P50150 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4 protein 20130415 {GO:0005515=IPI, GO:0030308=IMP, GO:0006112=TAS, GO:0008277=TAS, GO:0005886=TAS, GO:0007186=IEA, GO:0071377=TAS, GO:0005834=IEA, GO:0007268=TAS, GO:0044281=TAS, GO:0004871=IEA} G-protein coupled receptor signaling pathway, cellular response to glucagon stimulus, energy reserve metabolic process, negative regulation of cell growth, regulation of G-protein coupled receptor protein signaling pathway, small molecule metabolic process, synaptic transmission heterotrimeric G-protein complex, plasma membrane protein binding, signal transducer activity Human UniProtKB:Q3MMY3 GNG5 GOC UniProtKB {GO:0006184=PMID:10819326, GO:0007165=PMID:9790912, GO:0006112=Reactome:REACT_1505, GO:0005886=Reactome:REACT_25066, GO:0007186=PMID:20277477, GO:0071377=Reactome:REACT_1665, GO:0005834=PMID:9790912, GO:0003924=PMID:10819326, GO:0007268=Reactome:REACT_13685, GO:0044281=Reactome:REACT_111217, GO:0004871=PMID:20277477} P63218 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5 protein 20130413 {GO:0006184=NAS, GO:0007165=NAS, GO:0006112=TAS, GO:0005886=TAS, GO:0007186=NAS, GO:0071377=TAS, GO:0005834=NAS, GO:0003924=NAS, GO:0007268=TAS, GO:0044281=TAS, GO:0004871=NAS} G-protein coupled receptor signaling pathway, GTP catabolic process, cellular response to glucagon stimulus, energy reserve metabolic process, signal transduction, small molecule metabolic process, synaptic transmission heterotrimeric G-protein complex, plasma membrane GTPase activity, signal transducer activity Human GNG7 Reactome UniProtKB {GO:0005886=Reactome:REACT_25066, GO:0005834=GO_REF:0000002, GO:0007268=Reactome:REACT_13685, GO:0044281=Reactome:REACT_111217, GO:0008277=PMID:9600093, GO:0006112=Reactome:REACT_1505, GO:0007186=GO_REF:0000002, GO:0071377=Reactome:REACT_1665, GO:0001662=GO_REF:0000019, GO:0007626=GO_REF:0000019, GO:0004871=GO_REF:0000019, GO:0045761=GO_REF:0000019, GO:0007168=GO_REF:0000019} O60262 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7 protein 20130301 {GO:0005886=TAS, GO:0005834=IEA, GO:0007268=TAS, GO:0044281=TAS, GO:0008277=TAS, GO:0006112=TAS, GO:0007186=IEA, GO:0071377=TAS, GO:0001662=IEA, GO:0007626=IEA, GO:0004871=IEA, GO:0045761=IEA, GO:0007168=IEA} G-protein coupled receptor signaling pathway, behavioral fear response, cellular response to glucagon stimulus, energy reserve metabolic process, locomotory behavior, receptor guanylyl cyclase signaling pathway, regulation of G-protein coupled receptor protein signaling pathway, regulation of adenylate cyclase activity, small molecule metabolic process, synaptic transmission heterotrimeric G-protein complex, plasma membrane signal transducer activity Human GNG8 GOC UniProtKB {GO:0006184=PMID:10819326, GO:0006112=Reactome:REACT_1505, GO:0005886=Reactome:REACT_25066, GO:0007186=PMID:10819326, GO:0071377=Reactome:REACT_1665, GO:0005834=GO_REF:0000002, GO:0003924=PMID:10819326, GO:0007268=Reactome:REACT_13685, GO:0005576=GO_REF:0000029, GO:0044281=Reactome:REACT_111217, GO:0004871=PMID:10819326, GO:0007399=GO_REF:0000019} Q9UK08 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8 protein 20130413 {GO:0006184=NAS, GO:0006112=TAS, GO:0005886=TAS, GO:0007186=NAS, GO:0071377=TAS, GO:0005834=IEA, GO:0003924=NAS, GO:0007268=TAS, GO:0005576=NAS, GO:0044281=TAS, GO:0004871=NAS, GO:0007399=IEA} G-protein coupled receptor signaling pathway, GTP catabolic process, cellular response to glucagon stimulus, energy reserve metabolic process, nervous system development, small molecule metabolic process, synaptic transmission extracellular region, heterotrimeric G-protein complex, plasma membrane GTPase activity, signal transducer activity Human GNGT1 GOC UniProtKB {GO:0005886=Reactome:REACT_25066, GO:0005834=GO_REF:0000019, GO:0003924=PMID:8661128, GO:0007268=Reactome:REACT_13685, GO:0071456=GO_REF:0000019, GO:0006184=PMID:8661128, GO:0001917=GO_REF:0000019, GO:0007165=PMID:8661128, GO:0008104=GO_REF:0000019, GO:0007186=GO_REF:0000002, GO:0010659=GO_REF:0000019, GO:0004871=GO_REF:0000037, GO:0007602=GO_REF:0000019, GO:0042462=GO_REF:0000019, GO:0001750=GO_REF:0000019} P63211 Guanine nucleotide-binding protein G(T) subunit gamma-T1 protein 20130413 {GO:0005886=TAS, GO:0005834=IEA, GO:0003924=TAS, GO:0007268=TAS, GO:0071456=IEA, GO:0006184=TAS, GO:0001917=IEA, GO:0007165=NAS, GO:0008104=IEA, GO:0007186=IEA, GO:0010659=IEA, GO:0004871=IEA, GO:0007602=IEA, GO:0042462=IEA, GO:0001750=IEA} G-protein coupled receptor signaling pathway, GTP catabolic process, cardiac muscle cell apoptotic process, cellular response to hypoxia, eye photoreceptor cell development, phototransduction, protein localization, signal transduction, synaptic transmission heterotrimeric G-protein complex, photoreceptor inner segment, photoreceptor outer segment, plasma membrane GTPase activity, signal transducer activity Human GNGT2 GOC UniProtKB {GO:0006184=PMID:9286705, GO:0005886=Reactome:REACT_25066, GO:0007186=PMID:9286705, GO:0005834=PMID:10570481, GO:0003924=PMID:10570481, GO:0007268=Reactome:REACT_13685, GO:0005576=GO_REF:0000029, GO:0004871=PMID:9286705, GO:0007602=PMID:9286705} O14610 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2 protein 20130413 {GO:0006184=NAS, GO:0005886=TAS, GO:0007186=NAS, GO:0005834=IDA, GO:0003924=IDA, GO:0007268=TAS, GO:0005576=NAS, GO:0004871=NAS, GO:0007602=NAS} G-protein coupled receptor signaling pathway, GTP catabolic process, phototransduction, synaptic transmission extracellular region, heterotrimeric G-protein complex, plasma membrane GTPase activity, signal transducer activity Human GNL1 GOC UniProtKB {GO:0006184=GO_REF:0000033, GO:0007165=PMID:8180467, GO:0005198=PMID:8180467, GO:0042254=GO_REF:0000033, GO:0003924=GO_REF:0000033, GO:0005525=PMID:8180467, GO:0005615=PMID:8180467, GO:0002456=PMID:8180467, GO:0006974=PMID:17525332, GO:0005829=GO_REF:0000033} P36915 Guanine nucleotide-binding protein-like 1 protein 20130413 {GO:0006184=IBA, GO:0007165=NAS, GO:0005198=NAS, GO:0042254=IBA, GO:0003924=IBA, GO:0005525=NAS, GO:0005615=NAS, GO:0002456=NAS, GO:0006974=IDA, GO:0005829=IBA} GTP catabolic process, T cell mediated immunity, response to DNA damage stimulus, ribosome biogenesis, signal transduction cytosol, extracellular space GTP binding, GTPase activity, structural molecule activity Human PANTHER:PTN000119716 GNL2 GOC UniProtKB {GO:0006184=PMID:8822211, GO:0008150=GO_REF:0000015, GO:0042254=GO_REF:0000033, GO:0003924=GO_REF:0000033, GO:0005730=GO_REF:0000052, GO:0005634=PMID:8822211, GO:0005525=PMID:8822211} Q13823 Nucleolar GTP-binding protein 2 protein 20130413 {GO:0006184=NAS, GO:0008150=ND, GO:0042254=IBA, GO:0003924=IBA, GO:0005730=IDA, GO:0005634=TAS, GO:0005525=NAS} GTP catabolic process, biological_process, ribosome biogenesis nucleolus, nucleus GTP binding, GTPase activity Human GNL3 GOC UniProtKB {GO:0006184=GO_REF:0000033, GO:0005515=PMID:21988832, GO:0008283=GO_REF:0000019, GO:0042254=GO_REF:0000033, GO:0042127=GO_REF:0000024, GO:0003924=GO_REF:0000033, GO:0005730=GO_REF:0000024, GO:0005634=GO_REF:0000024, GO:0005654=GO_REF:0000019, GO:0005525=GO_REF:0000024} Q9BVP2 Guanine nucleotide-binding protein-like 3 protein 20130413 {GO:0006184=IBA, GO:0005515=IPI, GO:0008283=IEA, GO:0042254=IBA, GO:0042127=ISS, GO:0003924=IBA, GO:0005730=ISS, GO:0005634=ISS, GO:0005654=IEA, GO:0005525=ISS} GTP catabolic process, cell proliferation, regulation of cell proliferation, ribosome biogenesis nucleolus, nucleoplasm, nucleus GTP binding, GTPase activity, protein binding Human PANTHER:PTN000119716 GNL3L GOC UniProtKB {GO:0006184=GO_REF:0000033, GO:0005739=GO_REF:0000052, GO:0005515=PMID:21132010, GO:0042254=GO_REF:0000033, GO:0005730=GO_REF:0000052, GO:0003924=GO_REF:0000033, GO:0005634=GO_REF:0000052, GO:0005525=GO_REF:0000037} Q9NVN8 Guanine nucleotide-binding protein-like 3-like protein protein 20130413 {GO:0006184=IBA, GO:0005739=IDA, GO:0005515=IPI, GO:0042254=IBA, GO:0005730=IDA, GO:0003924=IBA, GO:0005634=IDA, GO:0005525=IEA} GTP catabolic process, ribosome biogenesis mitochondrion, nucleolus, nucleus GTP binding, GTPase activity, protein binding Human PANTHER:PTN000119716 GNLY PINC UniProtKB {GO:0006968=PMID:9756476, GO:0050832=GO_REF:0000037, GO:0031640=GO_REF:0000037, GO:0005615=PMID:2212946, GO:0042742=GO_REF:0000037} P22749 Granulysin protein 20030904 {GO:0006968=TAS, GO:0050832=IEA, GO:0031640=IEA, GO:0005615=TAS, GO:0042742=IEA} cellular defense response, defense response to bacterium, defense response to fungus, killing of cells of other organism extracellular space Human GNMT HPA UniProtKB {GO:0005515=PMID:21988832, GO:0006111=GO_REF:0000019, GO:0005737=GO_REF:0000052, GO:0005542=GO_REF:0000037, GO:0051289=PMID:15340920, GO:0005977=GO_REF:0000019, GO:0016594=PMID:15340920, GO:0046500=PMID:15340920, GO:0006555=GO_REF:0000019, GO:0006730=GO_REF:0000019, GO:0017174=PMID:15340920, GO:0006464=PMID:10843803} Q14749 Glycine N-methyltransferase protein 20101115 {GO:0005515=IPI, GO:0006111=IEA, GO:0005737=IDA, GO:0005542=IEA, GO:0051289=IPI, GO:0005977=IEA, GO:0016594=IDA, GO:0046500=IDA, GO:0006555=IEA, GO:0006730=IEA, GO:0017174=IDA, GO:0006464=NAS} S-adenosylmethionine metabolic process, cellular protein modification process, glycogen metabolic process, methionine metabolic process, one-carbon metabolic process, protein homotetramerization, regulation of gluconeogenesis cytoplasm folic acid binding, glycine N-methyltransferase activity, glycine binding, protein binding Human GNPAT InterPro UniProtKB {GO:0005782=Reactome:REACT_16930, GO:0030913=GO_REF:0000019, GO:0007584=GO_REF:0000019, GO:0008611=Reactome:REACT_1407, GO:0016290=PMID:8186247, GO:0042493=GO_REF:0000019, GO:0005102=PMID:20178365, GO:0021587=GO_REF:0000019, GO:0004366=GO_REF:0000002, GO:0044281=Reactome:REACT_111217, GO:0008654=GO_REF:0000002, GO:0016287=Reactome:REACT_15, GO:0007416=GO_REF:0000019, GO:0005739=GO_REF:0000019, GO:0042594=GO_REF:0000019, GO:0070542=GO_REF:0000019, GO:0016020=GO_REF:0000002, GO:0006644=Reactome:REACT_120870, GO:0006654=Reactome:REACT_120906, GO:0044255=Reactome:REACT_16957, GO:0005778=Reactome:REACT_121344, GO:0016044=GO_REF:0000019, GO:0046474=Reactome:REACT_121401, GO:0005777=PMID:15687349} Q5TBH8 Dihydroxyacetone phosphate acyltransferase protein 20130413 {GO:0005782=TAS, GO:0030913=IEA, GO:0007584=IEA, GO:0008611=TAS, GO:0016290=IDA, GO:0042493=IEA, GO:0005102=IPI, GO:0021587=IEA, GO:0004366=IEA, GO:0044281=TAS, GO:0008654=IEA, GO:0016287=TAS, GO:0007416=IEA, GO:0005739=IEA, GO:0042594=IEA, GO:0070542=IEA, GO:0016020=IEA, GO:0006644=TAS, GO:0006654=TAS, GO:0044255=TAS, GO:0005778=TAS, GO:0016044=IEA, GO:0046474=TAS, GO:0005777=IDA} cellular lipid metabolic process, cellular membrane organization, cerebellum morphogenesis, ether lipid biosynthetic process, glycerophospholipid biosynthetic process, paranodal junction assembly, phosphatidic acid biosynthetic process, phospholipid biosynthetic process, phospholipid metabolic process, response to drug, response to fatty acid, response to nutrient, response to starvation, small molecule metabolic process, synapse assembly membrane, mitochondrion, peroxisomal matrix, peroxisomal membrane, peroxisome glycerol-3-phosphate O-acyltransferase activity, glycerone-phosphate O-acyltransferase activity, palmitoyl-CoA hydrolase activity, receptor binding Human InterPro:IPR022284 GNPDA1 PINC UniProtKB {GO:0007338=PMID:9714720, GO:0005737=GO_REF:0000024, GO:0004342=PMID:9438414, GO:0016787=GO_REF:0000037, GO:0005975=GO_REF:0000037, GO:0006043=PMID:9438414, GO:0006044=GO_REF:0000002, GO:0006091=PMID:9438414} P46926 Glucosamine-6-phosphate isomerase 1 protein 20030904 {GO:0007338=TAS, GO:0005737=ISS, GO:0004342=IMP, GO:0016787=IEA, GO:0005975=IEA, GO:0006043=IMP, GO:0006044=IEA, GO:0006091=IMP} N-acetylglucosamine metabolic process, carbohydrate metabolic process, generation of precursor metabolites and energy, glucosamine catabolic process, single fertilization cytoplasm glucosamine-6-phosphate deaminase activity, hydrolase activity Human GNPDA2 UniProtKB UniProtKB {GO:0005737=GO_REF:0000039, GO:0004342=GO_REF:0000003, GO:0016787=GO_REF:0000037, GO:0005975=GO_REF:0000037, GO:0006044=GO_REF:0000002} Q8TDQ7 Glucosamine-6-phosphate isomerase 2 protein 20130413 {GO:0005737=IEA, GO:0004342=IEA, GO:0016787=IEA, GO:0005975=IEA, GO:0006044=IEA} N-acetylglucosamine metabolic process, carbohydrate metabolic process cytoplasm glucosamine-6-phosphate deaminase activity, hydrolase activity Human UniProtKB-SubCell:SL-0086 GNPNAT1 Reactome UniProtKB {GO:0005793=GO_REF:0000019, GO:0005794=GO_REF:0000019, GO:0005770=GO_REF:0000019, GO:0006041=GO_REF:0000019, GO:0006044=GO_REF:0000019, GO:0006048=Reactome:REACT_22394, GO:0005829=Reactome:REACT_22233, GO:0001889=GO_REF:0000019, GO:0004343=Reactome:REACT_22233, GO:0000139=GO_REF:0000039, GO:0048029=GO_REF:0000019, GO:0006488=Reactome:REACT_22433, GO:0044267=Reactome:REACT_17015, GO:0010008=GO_REF:0000039, GO:0043687=Reactome:REACT_22161, GO:0018279=Reactome:REACT_22426} Q96EK6 Glucosamine 6-phosphate N-acetyltransferase protein 20091207 {GO:0005793=IEA, GO:0005794=IEA, GO:0005770=IEA, GO:0006041=IEA, GO:0006044=IEA, GO:0006048=TAS, GO:0005829=TAS, GO:0001889=IEA, GO:0004343=TAS, GO:0000139=IEA, GO:0048029=IEA, GO:0006488=TAS, GO:0044267=TAS, GO:0010008=IEA, GO:0043687=TAS, GO:0018279=TAS} N-acetylglucosamine metabolic process, UDP-N-acetylglucosamine biosynthetic process, cellular protein metabolic process, dolichol-linked oligosaccharide biosynthetic process, glucosamine metabolic process, liver development, post-translational protein modification, protein N-linked glycosylation via asparagine Golgi apparatus, Golgi membrane, cytosol, endoplasmic reticulum-Golgi intermediate compartment, endosome membrane, late endosome glucosamine 6-phosphate N-acetyltransferase activity, monosaccharide binding Human GNPTAB UniProtKB UniProtKB {GO:0009306=GO_REF:0000019, GO:0000139=GO_REF:0000039, GO:0003976=GO_REF:0000003, GO:0005509=GO_REF:0000002, GO:0046835=GO_REF:0000019, GO:0005634=GO_REF:0000002, GO:0016021=GO_REF:0000037, GO:0030154=GO_REF:0000002, GO:0008134=GO_REF:0000002} Q3T906 N-acetylglucosamine-1-phosphotransferase subunits alpha/beta protein 20130413 {GO:0009306=IEA, GO:0000139=IEA, GO:0003976=IEA, GO:0005509=IEA, GO:0046835=IEA, GO:0005634=IEA, GO:0016021=IEA, GO:0030154=IEA, GO:0008134=IEA} carbohydrate phosphorylation, cell differentiation, protein secretion Golgi membrane, integral to membrane, nucleus UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity, calcium ion binding, transcription factor binding Human UniProtKB-SubCell:SL-0134 GNPTG UniProtKB UniProtKB {GO:0005794=GO_REF:0000039, GO:0005576=GO_REF:0000039} Q9UJJ9 N-acetylglucosamine-1-phosphotransferase subunit gamma protein 20130413 {GO:0005794=IEA, GO:0005576=IEA} Golgi apparatus, extracellular region Human UniProtKB-SubCell:SL-0132 GNRH1 Reactome UniProtKB {GO:0010468=GO_REF:0000019, GO:0007565=GO_REF:0000019, GO:0043066=GO_REF:0000019, GO:0008285=PMID:10832105, GO:0045471=GO_REF:0000019, GO:0007267=PMID:1310542, GO:0031960=GO_REF:0000019, GO:0005576=Reactome:REACT_22436, GO:0007275=GO_REF:0000019, GO:0042698=GO_REF:0000019, GO:0005615=GO_REF:0000019, GO:0007165=PMID:8692981, GO:0005179=PMID:2863757, GO:0005183=GO_REF:0000002} P01148 Progonadoliberin-1 protein 20100609 {GO:0010468=IEA, GO:0007565=IEA, GO:0043066=IEA, GO:0008285=TAS, GO:0045471=IEA, GO:0007267=TAS, GO:0031960=IEA, GO:0005576=TAS, GO:0007275=IEA, GO:0042698=IEA, GO:0005615=IEA, GO:0007165=TAS, GO:0005179=TAS, GO:0005183=IEA} cell-cell signaling, female pregnancy, multicellular organismal development, negative regulation of apoptotic process, negative regulation of cell proliferation, ovulation cycle, regulation of gene expression, response to corticosteroid stimulus, response to ethanol, signal transduction extracellular region, extracellular space gonadotropin hormone-releasing hormone activity, hormone activity Human GNRH2 Reactome UniProtKB {GO:0007165=PMID:9419371, GO:0005179=GO_REF:0000037, GO:0005576=Reactome:REACT_22436, GO:0007275=GO_REF:0000002} O43555 Progonadoliberin-2 protein 20100609 {GO:0007165=TAS, GO:0005179=IEA, GO:0005576=TAS, GO:0007275=IEA} multicellular organismal development, signal transduction extracellular region hormone activity Human GNRHR GOC UniProtKB {GO:0005886=Reactome:REACT_22436, GO:0007186=PMID:8386108, GO:0016020=PMID:9259321, GO:0005887=PMID:8386108, GO:0007275=PMID:10686191, GO:0097211=PMID:8386108, GO:0004968=GO_REF:0000002} P30968 Gonadotropin-releasing hormone receptor protein 20130413 {GO:0005886=TAS, GO:0007186=TAS, GO:0016020=TAS, GO:0005887=TAS, GO:0007275=TAS, GO:0097211=TAS, GO:0004968=IEA} G-protein coupled receptor signaling pathway, cellular response to gonadotropin-releasing hormone, multicellular organismal development integral to plasma membrane, membrane, plasma membrane gonadotropin-releasing hormone receptor activity Human GNS IntAct UniProtKB {GO:0005515=PMID:17474147, GO:0005975=Reactome:REACT_474, GO:0042340=Reactome:REACT_121313, GO:0006027=PMID:3689315, GO:0044281=Reactome:REACT_111217, GO:0008484=PMID:15962010, GO:0008449=GO_REF:0000003, GO:0030203=Reactome:REACT_121315, GO:0005764=GO_REF:0000002, GO:0046872=GO_REF:0000037, GO:0043202=Reactome:REACT_120828, GO:0042339=Reactome:REACT_121288} P15586 N-acetylglucosamine-6-sulfatase protein 20130415 {GO:0005515=IPI, GO:0005975=TAS, GO:0042340=TAS, GO:0006027=TAS, GO:0044281=TAS, GO:0008484=IDA, GO:0008449=IEA, GO:0030203=TAS, GO:0005764=IEA, GO:0046872=IEA, GO:0043202=TAS, GO:0042339=TAS} carbohydrate metabolic process, glycosaminoglycan catabolic process, glycosaminoglycan metabolic process, keratan sulfate catabolic process, keratan sulfate metabolic process, small molecule metabolic process lysosomal lumen, lysosome N-acetylglucosamine-6-sulfatase activity, metal ion binding, protein binding, sulfuric ester hydrolase activity Human UniProtKB:P16333 GOLGA1 PINC UniProtKB {GO:0005802=GO_REF:0000019, GO:0048471=GO_REF:0000019, GO:0005794=PMID:9324025, GO:0032580=GO_REF:0000039, GO:0000042=GO_REF:0000002} Q92805 Golgin subfamily A member 1 protein 20030904 {GO:0005802=IEA, GO:0048471=IEA, GO:0005794=TAS, GO:0032580=IEA, GO:0000042=IEA} protein targeting to Golgi Golgi apparatus, Golgi cisterna membrane, perinuclear region of cytoplasm, trans-Golgi network Human GOLGA2 HPA UniProtKB {GO:0005515=PMID:23455922, GO:0005801=PMID:22802641, GO:0005794=GO_REF:0000052, GO:0000139=Reactome:REACT_147881, GO:0000088=Reactome:REACT_765, GO:0032580=GO_REF:0000039, GO:0000087=Reactome:REACT_910, GO:0000278=Reactome:REACT_152} Q08379 Golgin subfamily A member 2 protein 20100326 {GO:0005515=IPI, GO:0005801=IDA, GO:0005794=IDA, GO:0000139=TAS, GO:0000088=TAS, GO:0032580=IEA, GO:0000087=TAS, GO:0000278=TAS} M phase of mitotic cell cycle, mitotic cell cycle, mitotic prophase Golgi apparatus, Golgi cisterna membrane, Golgi membrane, cis-Golgi network protein binding Human GOLGA3 HPA UniProtKB {GO:0005215=PMID:8315394, GO:0005793=GO_REF:0000019, GO:0005794=GO_REF:0000052, GO:0000139=PMID:9295333, GO:0032580=GO_REF:0000039, GO:0005730=GO_REF:0000052, GO:0017119=PMID:8315394, GO:0006891=PMID:8315394, GO:0005634=GO_REF:0000052} Q08378 Golgin subfamily A member 3 protein 20111111 {GO:0005215=NAS, GO:0005793=IEA, GO:0005794=IDA, GO:0000139=TAS, GO:0032580=IEA, GO:0005730=IDA, GO:0017119=IDA, GO:0006891=NAS, GO:0005634=IDA} intra-Golgi vesicle-mediated transport Golgi apparatus, Golgi cisterna membrane, Golgi membrane, Golgi transport complex, endoplasmic reticulum-Golgi intermediate compartment, nucleolus, nucleus transporter activity Human GOLGA4 IntAct UniProtKB {GO:0005802=PMID:1400343, GO:0005515=PMID:22705394, GO:0005737=PMID:15265687, GO:0051020=PMID:14580338, GO:0005794=PMID:19224922, GO:0000139=GO_REF:0000039, GO:0043001=PMID:15265687, GO:0016192=PMID:8626529, GO:0000042=GO_REF:0000002} Q13439 Golgin subfamily A member 4 protein 20130415 {GO:0005802=TAS, GO:0005515=IPI, GO:0005737=IDA, GO:0051020=IPI, GO:0005794=IDA, GO:0000139=IEA, GO:0043001=IDA, GO:0016192=TAS, GO:0000042=IEA} Golgi to plasma membrane protein transport, protein targeting to Golgi, vesicle-mediated transport Golgi apparatus, Golgi membrane, cytoplasm, trans-Golgi network GTPase binding, protein binding Human UniProtKB:Q96NW4 GOLGA5 HPA UniProtKB {GO:0005801=PMID:12538640, GO:0017137=PMID:12538640, GO:0005794=GO_REF:0000052, GO:0000139=GO_REF:0000039, GO:0031985=PMID:12538640, GO:0007030=PMID:12538640, GO:0048193=PMID:12538640, GO:0016021=PMID:9915833, GO:0042803=PMID:9915833} Q8TBA6 Golgin subfamily A member 5 protein 20080205 {GO:0005801=IDA, GO:0017137=IDA, GO:0005794=IDA, GO:0000139=IEA, GO:0031985=IDA, GO:0007030=IMP, GO:0048193=IMP, GO:0016021=IDA, GO:0042803=IPI} Golgi organization, Golgi vesicle transport Golgi apparatus, Golgi cisterna, Golgi membrane, cis-Golgi network, integral to membrane Rab GTPase binding, protein homodimerization activity Human GOLGA6L10 null null {} null null null null {} null null null GOLGA6L9 null null {} null null null null {} null null null GOLGA7 UniProtKB UniProtKB {GO:0000139=GO_REF:0000039} Q7Z5G4 Golgin subfamily A member 7 protein 20130413 {GO:0000139=IEA} Golgi membrane Human UniProtKB-SubCell:SL-0134 GOLGA8A InterPro UniProtKB {GO:0005794=GO_REF:0000002, GO:0032580=GO_REF:0000039} J3KQL3 Golgin subfamily A member 8A protein 20130413 {GO:0005794=IEA, GO:0032580=IEA} Golgi apparatus, Golgi cisterna membrane Human InterPro:IPR024858 GOLGA8B InterPro UniProtKB {GO:0005794=GO_REF:0000002, GO:0032580=GO_REF:0000039} C9J1B5 Golgin subfamily A member 8B protein 20130413 {GO:0005794=IEA, GO:0032580=IEA} Golgi apparatus, Golgi cisterna membrane Human InterPro:IPR024858 GOLGA8H InterPro UniProtKB {GO:0005794=GO_REF:0000002} P0CJ92 Golgin subfamily A member 8H protein 20130413 {GO:0005794=IEA} Golgi apparatus Human InterPro:IPR024858 GOLGA8J InterPro UniProtKB {GO:0005794=GO_REF:0000002} H3BRU0 Golgin subfamily A member 8J protein 20130413 {GO:0005794=IEA} Golgi apparatus Human InterPro:IPR024858 GOLGB1 HPA UniProtKB {GO:0005515=PMID:16169070, GO:0005793=PMID:15308636, GO:0005794=GO_REF:0000052, GO:0005795=PMID:7691276, GO:0000139=GO_REF:0000039, GO:0007030=PMID:7691276, GO:0016021=GO_REF:0000037} Q14789 Golgin subfamily B member 1 protein 20080205 {GO:0005515=IPI, GO:0005793=IDA, GO:0005794=IDA, GO:0005795=TAS, GO:0000139=IEA, GO:0007030=TAS, GO:0016021=IEA} Golgi organization Golgi apparatus, Golgi membrane, Golgi stack, endoplasmic reticulum-Golgi intermediate compartment, integral to membrane protein binding Human GOLIM4 HPA UniProtKB {GO:0005801=PMID:9201717, GO:0005794=GO_REF:0000052, GO:0005796=PMID:9201717, GO:0032580=GO_REF:0000039, GO:0005730=GO_REF:0000052, GO:0006810=GO_REF:0000037, GO:0005634=GO_REF:0000052, GO:0030139=PMID:9201717, GO:0016021=GO_REF:0000037, GO:0010008=GO_REF:0000039} O00461 Golgi integral membrane protein 4 protein 20101115 {GO:0005801=TAS, GO:0005794=IDA, GO:0005796=TAS, GO:0032580=IEA, GO:0005730=IDA, GO:0006810=IEA, GO:0005634=IDA, GO:0030139=TAS, GO:0016021=IEA, GO:0010008=IEA} transport Golgi apparatus, Golgi cisterna membrane, Golgi lumen, cis-Golgi network, endocytic vesicle, endosome membrane, integral to membrane, nucleolus, nucleus Human GOLM1 HPA UniProtKB {GO:0005515=PMID:21280149, GO:0005794=GO_REF:0000052, GO:0005887=PMID:10831838} Q8NBJ4 Golgi membrane protein 1 protein 20081203 {GO:0005515=IPI, GO:0005794=IDA, GO:0005887=TAS} Golgi apparatus, integral to plasma membrane protein binding Human GOLPH3 HPA UniProtKB {GO:0005802=PMID:19553991, GO:0005515=PMID:22190034, GO:0031965=GO_REF:0000052, GO:0032008=PMID:19553991, GO:0010821=PMID:16263763, GO:0005886=GO_REF:0000052, GO:0008283=PMID:19553991, GO:0008289=GO_REF:0000037, GO:0005829=PMID:16263763, GO:0005739=PMID:16263763, GO:0005758=GO_REF:0000039, GO:0005737=GO_REF:0000052, GO:0032580=GO_REF:0000039, GO:0005768=GO_REF:0000039} Q9H4A6 Golgi phosphoprotein 3 protein 20111111 {GO:0005802=IDA, GO:0005515=IPI, GO:0031965=IDA, GO:0032008=IMP, GO:0010821=IDA, GO:0005886=IDA, GO:0008283=IMP, GO:0008289=IEA, GO:0005829=IDA, GO:0005739=IDA, GO:0005758=IEA, GO:0005737=IDA, GO:0032580=IEA, GO:0005768=IEA} cell proliferation, positive regulation of TOR signaling cascade, regulation of mitochondrion organization Golgi cisterna membrane, cytoplasm, cytosol, endosome, mitochondrial intermembrane space, mitochondrion, nuclear membrane, plasma membrane, trans-Golgi network lipid binding, protein binding Human GOLPH3L IntAct UniProtKB {GO:0005515=PMID:23275563, GO:0032580=GO_REF:0000039, GO:0008289=GO_REF:0000037} Q9H4A5 Golgi phosphoprotein 3-like protein 20130415 {GO:0005515=IPI, GO:0032580=IEA, GO:0008289=IEA} Golgi cisterna membrane lipid binding, protein binding Human UniProtKB:P42858 GOLT1B GOC UniProtKB {GO:0007165=PMID:12761501, GO:0000139=GO_REF:0000039, GO:0005783=GO_REF:0000054, GO:0004871=PMID:12761501, GO:0016021=GO_REF:0000037, GO:0043123=PMID:12761501, GO:0015031=GO_REF:0000037, GO:0016192=GO_REF:0000002} Q9Y3E0 Vesicle transport protein GOT1B protein 20130413 {GO:0007165=IMP, GO:0000139=IEA, GO:0005783=IDA, GO:0004871=IMP, GO:0016021=IEA, GO:0043123=IMP, GO:0015031=IEA, GO:0016192=IEA} positive regulation of I-kappaB kinase/NF-kappaB cascade, protein transport, signal transduction, vesicle-mediated transport Golgi membrane, endoplasmic reticulum, integral to membrane signal transducer activity Human GON4L HPA UniProtKB {GO:0006355=GO_REF:0000002, GO:0003682=GO_REF:0000002, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0003677=GO_REF:0000002} Q3T8J9 GON-4-like protein protein 20111111 {GO:0006355=IEA, GO:0003682=IEA, GO:0005730=IDA, GO:0005634=IDA, GO:0003677=IEA} regulation of transcription, DNA-dependent nucleolus, nucleus DNA binding, chromatin binding NOT Human GOPC HPA UniProtKB {GO:0005515=PMID:11707463, GO:0005794=GO_REF:0000052, GO:0030054=GO_REF:0000037, GO:0005886=PMID:11707463, GO:0007289=GO_REF:0000019, GO:0043004=PMID:11707463, GO:0014069=GO_REF:0000039, GO:0045176=PMID:11707463, GO:0006893=PMID:11707463, GO:0015031=GO_REF:0000037, GO:0008022=GO_REF:0000019, GO:0042803=GO_REF:0000019, GO:0044325=PMID:11707463, GO:0006888=PMID:11707463, GO:0005109=GO_REF:0000019, GO:0043234=PMID:18468998, GO:0005737=GO_REF:0000052, GO:0005083=GO_REF:0000019, GO:0016020=PMID:11707463, GO:0000139=GO_REF:0000039, GO:0045211=GO_REF:0000037, GO:0051260=PMID:11707463, GO:0030140=PMID:11384996} Q9HD26 Golgi-associated PDZ and coiled-coil motif-containing protein protein 20100326 {GO:0005515=IPI, GO:0005794=IDA, GO:0030054=IEA, GO:0005886=NAS, GO:0007289=IEA, GO:0043004=NAS, GO:0014069=IEA, GO:0045176=NAS, GO:0006893=NAS, GO:0015031=IEA, GO:0008022=IEA, GO:0042803=IEA, GO:0044325=IPI, GO:0006888=NAS, GO:0005109=IEA, GO:0043234=IDA, GO:0005737=IDA, GO:0005083=IEA, GO:0016020=IDA, GO:0000139=IEA, GO:0045211=IEA, GO:0051260=IPI, GO:0030140=NAS} ER to Golgi vesicle-mediated transport, Golgi to plasma membrane transport, apical protein localization, cytoplasmic sequestering of CFTR protein, protein homooligomerization, protein transport, spermatid nucleus differentiation Golgi apparatus, Golgi membrane, cell junction, cytoplasm, membrane, plasma membrane, postsynaptic density, postsynaptic membrane, protein complex, trans-Golgi network transport vesicle frizzled binding, ion channel binding, protein C-terminus binding, protein binding, protein homodimerization activity, small GTPase regulator activity Human GORAB HPA UniProtKB {GO:0005515=PMID:15781263, GO:0005737=GO_REF:0000052, GO:0005794=GO_REF:0000052, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052} Q5T7V8 RAB6-interacting golgin protein 20111111 {GO:0005515=IPI, GO:0005737=IDA, GO:0005794=IDA, GO:0005730=IDA, GO:0005634=IDA} Golgi apparatus, cytoplasm, nucleolus, nucleus protein binding Human GORASP1 Reactome UniProtKB {GO:0005794=GO_REF:0000019, GO:0000139=Reactome:REACT_147881, GO:0000088=Reactome:REACT_765, GO:0000087=Reactome:REACT_910, GO:0000278=Reactome:REACT_152, GO:0015031=GO_REF:0000037} Q9BQQ3 Golgi reassembly-stacking protein 1 protein 20120328 {GO:0005794=IEA, GO:0000139=TAS, GO:0000088=TAS, GO:0000087=TAS, GO:0000278=TAS, GO:0015031=IEA} M phase of mitotic cell cycle, mitotic cell cycle, mitotic prophase, protein transport Golgi apparatus, Golgi membrane Human GORASP2 HPA UniProtKB {GO:0005515=PMID:21884936, GO:0006996=PMID:21515684, GO:0005794=GO_REF:0000052, GO:0000139=Reactome:REACT_147850, GO:0000088=Reactome:REACT_765, GO:0016020=PMID:21515684, GO:0000087=Reactome:REACT_910, GO:0000278=Reactome:REACT_152} Q9H8Y8 Golgi reassembly-stacking protein 2 protein 20110516 {GO:0005515=IPI, GO:0006996=IMP, GO:0005794=IDA, GO:0000139=TAS, GO:0000088=TAS, GO:0016020=TAS, GO:0000087=TAS, GO:0000278=TAS} M phase of mitotic cell cycle, mitotic cell cycle, mitotic prophase, organelle organization Golgi apparatus, Golgi membrane, membrane protein binding Human GOSR1 BHF-UCL UniProtKB {GO:0006888=GO_REF:0000019, GO:0005484=PMID:15215310, GO:0005801=GO_REF:0000019, GO:0005794=PMID:15215310, GO:0000139=PMID:21669198, GO:0042147=PMID:15215310, GO:0031201=PMID:15215310, GO:0006891=PMID:8636227, GO:0016021=GO_REF:0000019, GO:0015031=GO_REF:0000037} O95249 Golgi SNAP receptor complex member 1 protein 20130121 {GO:0006888=IEA, GO:0005484=IDA, GO:0005801=IEA, GO:0005794=IDA, GO:0000139=IDA, GO:0042147=IDA, GO:0031201=TAS, GO:0006891=TAS, GO:0016021=IEA, GO:0015031=IEA} ER to Golgi vesicle-mediated transport, intra-Golgi vesicle-mediated transport, protein transport, retrograde transport, endosome to Golgi Golgi apparatus, Golgi membrane, SNARE complex, cis-Golgi network, integral to membrane SNAP receptor activity Human GOSR2 Reactome UniProtKB {GO:0006888=PMID:9349823, GO:0005215=PMID:9349823, GO:0000139=Reactome:REACT_116129, GO:0006944=PMID:9349823, GO:0005795=GO_REF:0000002, GO:0006810=GO_REF:0000002, GO:0016021=GO_REF:0000037, GO:0006987=Reactome:REACT_18368, GO:0015031=GO_REF:0000037, GO:0044267=Reactome:REACT_17015, GO:0030968=Reactome:REACT_18356} O14653 Golgi SNAP receptor complex member 2 protein 20130301 {GO:0006888=TAS, GO:0005215=TAS, GO:0000139=TAS, GO:0006944=TAS, GO:0005795=IEA, GO:0006810=IEA, GO:0016021=IEA, GO:0006987=TAS, GO:0015031=IEA, GO:0044267=TAS, GO:0030968=TAS} ER to Golgi vesicle-mediated transport, activation of signaling protein activity involved in unfolded protein response, cellular membrane fusion, cellular protein metabolic process, endoplasmic reticulum unfolded protein response, protein transport, transport Golgi membrane, Golgi stack, integral to membrane transporter activity Human GOT1 Reactome UniProtKB {GO:0031406=GO_REF:0000019, GO:0006531=GO_REF:0000024, GO:0006532=GO_REF:0000019, GO:0006533=PMID:2241899, GO:0008483=Reactome:REACT_75811, GO:0006094=Reactome:REACT_1520, GO:0044281=Reactome:REACT_111217, GO:0047801=GO_REF:0000024, GO:0005764=GO_REF:0000019, GO:0019551=GO_REF:0000019, GO:0019550=GO_REF:0000019, GO:0005829=Reactome:REACT_75811, GO:0034641=Reactome:REACT_13, GO:0005737=PMID:7060339, GO:0019509=Reactome:REACT_75881, GO:0006595=Reactome:REACT_14820, GO:0006103=GO_REF:0000024, GO:0006006=Reactome:REACT_723, GO:0043679=GO_REF:0000019, GO:0004609=GO_REF:0000019, GO:0004069=Reactome:REACT_2078, GO:0080130=GO_REF:0000003, GO:0006520=GO_REF:0000002, GO:0032869=PMID:8396422, GO:0009058=GO_REF:0000002, GO:0006536=GO_REF:0000024, GO:0005975=Reactome:REACT_474, GO:0006107=GO_REF:0000019, GO:0008652=Reactome:REACT_238, GO:0055089=GO_REF:0000019, GO:0051384=PMID:8396422, GO:0000096=Reactome:REACT_115639, GO:0006114=GO_REF:0000024, GO:0030170=GO_REF:0000002} P17174 Aspartate aminotransferase, cytoplasmic protein 20110516 {GO:0031406=IEA, GO:0006531=ISS, GO:0006532=IEA, GO:0006533=IDA, GO:0008483=TAS, GO:0006094=TAS, GO:0044281=TAS, GO:0047801=ISS, GO:0005764=IEA, GO:0019551=IEA, GO:0019550=IEA, GO:0005829=TAS, GO:0034641=TAS, GO:0005737=IDA, GO:0019509=TAS, GO:0006595=TAS, GO:0006103=ISS, GO:0006006=TAS, GO:0043679=IEA, GO:0004609=IEA, GO:0004069=TAS, GO:0080130=IEA, GO:0006520=IEA, GO:0032869=IEP, GO:0009058=IEA, GO:0006536=ISS, GO:0005975=TAS, GO:0006107=IEA, GO:0008652=TAS, GO:0055089=IEA, GO:0051384=IEP, GO:0000096=TAS, GO:0006114=ISS, GO:0030170=IEA} 2-oxoglutarate metabolic process, L-methionine salvage from methylthioadenosine, aspartate biosynthetic process, aspartate catabolic process, aspartate metabolic process, biosynthetic process, carbohydrate metabolic process, cellular amino acid biosynthetic process, cellular amino acid metabolic process, cellular nitrogen compound metabolic process, cellular response to insulin stimulus, fatty acid homeostasis, gluconeogenesis, glucose metabolic process, glutamate catabolic process to 2-oxoglutarate, glutamate catabolic process to aspartate, glutamate metabolic process, glycerol biosynthetic process, oxaloacetate metabolic process, polyamine metabolic process, response to glucocorticoid stimulus, small molecule metabolic process, sulfur amino acid metabolic process axon terminus, cytoplasm, cytosol, lysosome L-aspartate:2-oxoglutarate aminotransferase activity, L-cysteine:2-oxoglutarate aminotransferase activity, L-phenylalanine:2-oxoglutarate aminotransferase activity, carboxylic acid binding, phosphatidylserine decarboxylase activity, pyridoxal phosphate binding, transaminase activity Human GOT1L1 UniProtKB UniProtKB {GO:0006520=GO_REF:0000002, GO:0005737=GO_REF:0000039, GO:0009058=GO_REF:0000002, GO:0030170=GO_REF:0000002, GO:0008483=GO_REF:0000037} Q8NHS2 Putative aspartate aminotransferase, cytoplasmic 2 protein 20130413 {GO:0006520=IEA, GO:0005737=IEA, GO:0009058=IEA, GO:0030170=IEA, GO:0008483=IEA} biosynthetic process, cellular amino acid metabolic process cytoplasm pyridoxal phosphate binding, transaminase activity Human UniProtKB-SubCell:SL-0086 GOT2 BHF-UCL UniProtKB {GO:0006531=GO_REF:0000024, GO:0006532=GO_REF:0000019, GO:0005886=PMID:9537447, GO:0006533=PMID:2567216, GO:0045471=PMID:9537447, GO:0005743=GO_REF:0000019, GO:0006094=Reactome:REACT_1520, GO:0044281=Reactome:REACT_111217, GO:0019551=GO_REF:0000019, GO:0019550=GO_REF:0000019, GO:0005739=GO_REF:0000024, GO:0034641=Reactome:REACT_13, GO:0005759=Reactome:REACT_1632, GO:0006103=GO_REF:0000024, GO:0006006=Reactome:REACT_723, GO:0004069=Reactome:REACT_1632, GO:0080130=GO_REF:0000003, GO:0006520=GO_REF:0000002, GO:0009058=GO_REF:0000002, GO:0006536=GO_REF:0000024, GO:0005975=Reactome:REACT_474, GO:0006107=GO_REF:0000019, GO:0008652=Reactome:REACT_238, GO:0019470=PMID:21998747, GO:0030170=GO_REF:0000002, GO:0016212=GO_REF:0000003, GO:0015908=PMID:9537447} P00505 Aspartate aminotransferase, mitochondrial protein 20120710 {GO:0006531=ISS, GO:0006532=IEA, GO:0005886=IDA, GO:0006533=IDA, GO:0045471=IDA, GO:0005743=IEA, GO:0006094=TAS, GO:0044281=TAS, GO:0019551=IEA, GO:0019550=IEA, GO:0005739=ISS, GO:0034641=TAS, GO:0005759=TAS, GO:0006103=ISS, GO:0006006=TAS, GO:0004069=EXP, GO:0080130=IEA, GO:0006520=IEA, GO:0009058=IEA, GO:0006536=ISS, GO:0005975=TAS, GO:0006107=IEA, GO:0008652=TAS, GO:0019470=TAS, GO:0030170=IEA, GO:0016212=IEA, GO:0015908=IEP} 2-oxoglutarate metabolic process, 4-hydroxyproline catabolic process, aspartate biosynthetic process, aspartate catabolic process, aspartate metabolic process, biosynthetic process, carbohydrate metabolic process, cellular amino acid biosynthetic process, cellular amino acid metabolic process, cellular nitrogen compound metabolic process, fatty acid transport, gluconeogenesis, glucose metabolic process, glutamate catabolic process to 2-oxoglutarate, glutamate catabolic process to aspartate, glutamate metabolic process, oxaloacetate metabolic process, response to ethanol, small molecule metabolic process mitochondrial inner membrane, mitochondrial matrix, mitochondrion, plasma membrane L-aspartate:2-oxoglutarate aminotransferase activity, L-phenylalanine:2-oxoglutarate aminotransferase activity, kynurenine-oxoglutarate transaminase activity, pyridoxal phosphate binding Human GP1BA GOC UniProtKB {GO:0005515=PMID:15039442, GO:0005886=Reactome:REACT_24010, GO:0015057=PMID:12855810, GO:0030168=Reactome:REACT_798, GO:0031362=GO_REF:0000019, GO:0007599=GO_REF:0000019, GO:0000902=GO_REF:0000019, GO:0016020=PMID:15297306, GO:0030193=PMID:12855810, GO:0070493=PMID:3759960, GO:0005887=PMID:3353370, GO:0007596=Reactome:REACT_2051, GO:0007597=Reactome:REACT_326, GO:0007155=PMID:9410473, GO:0042730=PMID:12855810, GO:0007166=PMID:3353370} P07359 Platelet glycoprotein Ib alpha chain protein 20130413 {GO:0005515=IPI, GO:0005886=TAS, GO:0015057=TAS, GO:0030168=TAS, GO:0031362=IEA, GO:0007599=IEA, GO:0000902=IEA, GO:0016020=IDA, GO:0030193=TAS, GO:0070493=TAS, GO:0005887=TAS, GO:0007596=TAS, GO:0007597=TAS, GO:0007155=IDA, GO:0042730=IDA, GO:0007166=TAS} blood coagulation, blood coagulation, intrinsic pathway, cell adhesion, cell morphogenesis, cell surface receptor signaling pathway, fibrinolysis, hemostasis, platelet activation, regulation of blood coagulation, thrombin receptor signaling pathway anchored to external side of plasma membrane, integral to plasma membrane, membrane, plasma membrane protein binding, thrombin receptor activity Human GP1BB BHF-UCL UniProtKB {GO:0005515=PMID:4044584, GO:0005886=Reactome:REACT_24010, GO:0007596=Reactome:REACT_2051, GO:0005887=PMID:3353370, GO:0007597=Reactome:REACT_326, GO:0030168=Reactome:REACT_798, GO:0007155=GO_REF:0000037, GO:0007166=PMID:3353370, GO:0004888=PMID:3353370} P13224 Platelet glycoprotein Ib beta chain protein 20080914 {GO:0005515=IPI, GO:0005886=TAS, GO:0007596=TAS, GO:0005887=NAS, GO:0007597=TAS, GO:0030168=TAS, GO:0007155=IEA, GO:0007166=NAS, GO:0004888=NAS} blood coagulation, blood coagulation, intrinsic pathway, cell adhesion, cell surface receptor signaling pathway, platelet activation integral to plasma membrane, plasma membrane protein binding, transmembrane signaling receptor activity Human UniProtKB:P21333 GP2 UniProtKB UniProtKB {GO:0002412=GO_REF:0000019, GO:0016324=GO_REF:0000019, GO:0005576=GO_REF:0000039, GO:0031225=GO_REF:0000037, GO:0003823=GO_REF:0000019} P55259 Pancreatic secretory granule membrane major glycoprotein GP2 protein 20130413 {GO:0002412=IEA, GO:0016324=IEA, GO:0005576=IEA, GO:0031225=IEA, GO:0003823=IEA} antigen transcytosis by M cells in mucosal-associated lymphoid tissue anchored to membrane, apical plasma membrane, extracellular region antigen binding Human UniProtKB-SubCell:SL-0243 GP5 Reactome UniProtKB {GO:0010544=GO_REF:0000019, GO:0005886=Reactome:REACT_24010, GO:0007160=GO_REF:0000019, GO:0007596=Reactome:REACT_2051, GO:0005887=PMID:7690959, GO:0007597=Reactome:REACT_326, GO:0005518=GO_REF:0000019, GO:0030168=Reactome:REACT_798, GO:0007155=PMID:7690959} P40197 Platelet glycoprotein V protein 20130213 {GO:0010544=IEA, GO:0005886=TAS, GO:0007160=IEA, GO:0007596=TAS, GO:0005887=TAS, GO:0007597=TAS, GO:0005518=IEA, GO:0030168=TAS, GO:0007155=NAS} blood coagulation, blood coagulation, intrinsic pathway, cell adhesion, cell-matrix adhesion, negative regulation of platelet activation, platelet activation integral to plasma membrane, plasma membrane collagen binding Human GP6 IntAct UniProtKB {GO:0005515=PMID:1715582, GO:0005886=Reactome:REACT_23800, GO:0007596=Reactome:REACT_604, GO:0005887=GO_REF:0000019, GO:0005518=PMID:11027634, GO:0030168=Reactome:REACT_798, GO:0004872=PMID:11027634, GO:0050900=Reactome:REACT_12051, GO:0007167=PMID:9153205, GO:0004888=PMID:10822077} Q9HCN6 Platelet glycoprotein VI protein 20130415 {GO:0005515=IPI, GO:0005886=TAS, GO:0007596=TAS, GO:0005887=IEA, GO:0005518=TAS, GO:0030168=TAS, GO:0004872=TAS, GO:0050900=TAS, GO:0007167=TAS, GO:0004888=TAS} blood coagulation, enzyme linked receptor protein signaling pathway, leukocyte migration, platelet activation integral to plasma membrane, plasma membrane collagen binding, protein binding, receptor activity, transmembrane signaling receptor activity Human UniProtKB:P07948 GP9 Reactome UniProtKB {GO:0005886=Reactome:REACT_24010, GO:0007596=Reactome:REACT_2051, GO:0005887=PMID:2771955, GO:0007597=Reactome:REACT_326, GO:0030168=Reactome:REACT_798, GO:0007155=GO_REF:0000037} P14770 Platelet glycoprotein IX protein 20130213 {GO:0005886=TAS, GO:0007596=TAS, GO:0005887=TAS, GO:0007597=TAS, GO:0030168=TAS, GO:0007155=IEA} blood coagulation, blood coagulation, intrinsic pathway, cell adhesion, platelet activation integral to plasma membrane, plasma membrane Human GPA33 PINC UniProtKB {GO:0005887=PMID:9012807, GO:0004872=PMID:9012807} Q99795 Cell surface A33 antigen protein 20030904 {GO:0005887=TAS, GO:0004872=TAS} integral to plasma membrane receptor activity Human GPAA1 Reactome UniProtKB {GO:0006501=Reactome:REACT_1853, GO:0005515=PMID:10793132, GO:0034235=PMID:14660601, GO:0006461=PMID:14660601, GO:0015631=PMID:12052837, GO:0016255=Reactome:REACT_1830, GO:0005789=Reactome:REACT_1777, GO:0042765=PMID:15713669, GO:0006621=PMID:12052837, GO:0003923=PMID:9468317, GO:0044267=Reactome:REACT_17015, GO:0043687=Reactome:REACT_22161} O43292 Glycosylphosphatidylinositol anchor attachment 1 protein protein 20130213 {GO:0006501=TAS, GO:0005515=IPI, GO:0034235=IMP, GO:0006461=NAS, GO:0015631=NAS, GO:0016255=TAS, GO:0005789=TAS, GO:0042765=TAS, GO:0006621=NAS, GO:0003923=NAS, GO:0044267=TAS, GO:0043687=TAS} C-terminal protein lipidation, attachment of GPI anchor to protein, cellular protein metabolic process, post-translational protein modification, protein complex assembly, protein retention in ER lumen GPI-anchor transamidase complex, endoplasmic reticulum membrane GPI anchor binding, GPI-anchor transamidase activity, protein binding, tubulin binding Human GPAM Reactome UniProtKB {GO:0006637=GO_REF:0000019, GO:0070970=GO_REF:0000019, GO:0070236=GO_REF:0000019, GO:0005743=GO_REF:0000019, GO:0055089=GO_REF:0000019, GO:0005741=Reactome:REACT_147810, GO:0004366=PMID:18238778, GO:0044281=Reactome:REACT_111217, GO:0008654=GO_REF:0000002, GO:0009749=GO_REF:0000019, GO:0042104=GO_REF:0000019, GO:0051607=GO_REF:0000019, GO:0016020=GO_REF:0000002, GO:0006631=GO_REF:0000019, GO:0019432=Reactome:REACT_1190, GO:0016024=GO_REF:0000041, GO:0055091=GO_REF:0000019, GO:0050707=GO_REF:0000019, GO:0016021=GO_REF:0000037, GO:0040018=GO_REF:0000019, GO:0006644=Reactome:REACT_120870, GO:0006654=Reactome:REACT_120906, GO:0044255=Reactome:REACT_22279, GO:0046474=Reactome:REACT_121401} Q9HCL2 Glycerol-3-phosphate acyltransferase 1, mitochondrial protein 20130301 {GO:0006637=IEA, GO:0070970=IEA, GO:0070236=IEA, GO:0005743=IEA, GO:0055089=IEA, GO:0005741=TAS, GO:0004366=IMP, GO:0044281=TAS, GO:0008654=IEA, GO:0009749=IEA, GO:0042104=IEA, GO:0051607=IEA, GO:0016020=IEA, GO:0006631=IEA, GO:0019432=TAS, GO:0016024=IEA, GO:0055091=IEA, GO:0050707=IEA, GO:0016021=IEA, GO:0040018=IEA, GO:0006644=TAS, GO:0006654=TAS, GO:0044255=TAS, GO:0046474=TAS} CDP-diacylglycerol biosynthetic process, acyl-CoA metabolic process, cellular lipid metabolic process, defense response to virus, fatty acid homeostasis, fatty acid metabolic process, glycerophospholipid biosynthetic process, interleukin-2 secretion, negative regulation of activation-induced cell death of T cells, phosphatidic acid biosynthetic process, phospholipid biosynthetic process, phospholipid homeostasis, phospholipid metabolic process, positive regulation of activated T cell proliferation, positive regulation of multicellular organism growth, regulation of cytokine secretion, response to glucose stimulus, small molecule metabolic process, triglyceride biosynthetic process integral to membrane, membrane, mitochondrial inner membrane, mitochondrial outer membrane glycerol-3-phosphate O-acyltransferase activity Human GPANK1 InterPro UniProtKB {GO:0003676=GO_REF:0000002} O95872 G patch domain and ankyrin repeat-containing protein 1 protein 20130413 {GO:0003676=IEA} nucleic acid binding Human InterPro:IPR000467 GPAT2 Reactome UniProtKB {GO:0004366=GO_REF:0000024, GO:0005741=Reactome:REACT_121291, GO:0008654=GO_REF:0000002, GO:0044281=Reactome:REACT_111217, GO:0006072=GO_REF:0000024, GO:0005739=GO_REF:0000024, GO:0016020=GO_REF:0000002, GO:0019432=GO_REF:0000024, GO:0016024=GO_REF:0000041, GO:0016021=GO_REF:0000037, GO:0006644=Reactome:REACT_120870, GO:0006654=Reactome:REACT_120906, GO:0046474=Reactome:REACT_121401} Q6NUI2 Glycerol-3-phosphate acyltransferase 2, mitochondrial protein 20130301 {GO:0004366=ISS, GO:0005741=TAS, GO:0008654=IEA, GO:0044281=TAS, GO:0006072=ISS, GO:0005739=ISS, GO:0016020=IEA, GO:0019432=ISS, GO:0016024=IEA, GO:0016021=IEA, GO:0006644=TAS, GO:0006654=TAS, GO:0046474=TAS} CDP-diacylglycerol biosynthetic process, glycerol-3-phosphate metabolic process, glycerophospholipid biosynthetic process, phosphatidic acid biosynthetic process, phospholipid biosynthetic process, phospholipid metabolic process, small molecule metabolic process, triglyceride biosynthetic process integral to membrane, membrane, mitochondrial outer membrane, mitochondrion glycerol-3-phosphate O-acyltransferase activity Human GPATCH1 UniProtKB UniProtKB {GO:0000398=PMID:11991638, GO:0071013=PMID:11991638, GO:0003676=GO_REF:0000002} Q9BRR8 G patch domain-containing protein 1 protein 20110302 {GO:0000398=IC, GO:0071013=IDA, GO:0003676=IEA} mRNA splicing, via spliceosome catalytic step 2 spliceosome nucleic acid binding Human GPATCH2 UniProtKB UniProtKB {GO:0010923=PMID:19389623, GO:0003676=GO_REF:0000002} Q9NW75 G patch domain-containing protein 2 protein 20111103 {GO:0010923=IDA, GO:0003676=IEA} negative regulation of phosphatase activity nucleic acid binding Human GPATCH4 InterPro UniProtKB {GO:0003676=GO_REF:0000002} Q5T3I0 G patch domain-containing protein 4 protein 20130413 {GO:0003676=IEA} nucleic acid binding Human InterPro:IPR000467 GPATCH8 IntAct UniProtKB {GO:0005515=PMID:16713569, GO:0008150=GO_REF:0000015, GO:0003674=GO_REF:0000015, GO:0008270=GO_REF:0000002, GO:0005575=GO_REF:0000015, GO:0003676=GO_REF:0000002} Q9UKJ3 G patch domain-containing protein 8 protein 20130415 {GO:0005515=IPI, GO:0008150=ND, GO:0003674=ND, GO:0008270=IEA, GO:0005575=ND, GO:0003676=IEA} biological_process cellular_component molecular_function, nucleic acid binding, protein binding, zinc ion binding Human UniProtKB:P54253 GPBP1 UniProtKB UniProtKB {GO:0005737=GO_REF:0000039, GO:0003700=GO_REF:0000019, GO:0005634=GO_REF:0000039, GO:0045893=GO_REF:0000019, GO:0003677=GO_REF:0000019, GO:0006351=GO_REF:0000037} Q86WP2 Vasculin protein 20130413 {GO:0005737=IEA, GO:0003700=IEA, GO:0005634=IEA, GO:0045893=IEA, GO:0003677=IEA, GO:0006351=IEA} positive regulation of transcription, DNA-dependent, transcription, DNA-dependent cytoplasm, nucleus DNA binding, sequence-specific DNA binding transcription factor activity Human UniProtKB-SubCell:SL-0086 GPBP1L1 UniProtKB UniProtKB {GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q9HC44 Vasculin-like protein 1 protein 20130413 {GO:0006355=IEA, GO:0005634=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus DNA binding Human UniProtKB-SubCell:SL-0191 GPC1 Reactome UniProtKB {GO:0005886=Reactome:REACT_160272, GO:0007603=Reactome:REACT_160125, GO:0044281=Reactome:REACT_111217, GO:0031225=GO_REF:0000037, GO:0005615=GO_REF:0000039, GO:0014037=GO_REF:0000024, GO:0007411=Reactome:REACT_18266, GO:0030200=PMID:12732622, GO:0030204=Reactome:REACT_121206, GO:2001016=GO_REF:0000024, GO:0030203=Reactome:REACT_121408, GO:0043202=Reactome:REACT_121392, GO:0005507=PMID:12732622, GO:0017134=GO_REF:0000024, GO:0005796=Reactome:REACT_121320, GO:0005975=Reactome:REACT_474, GO:0005578=GO_REF:0000024, GO:0006027=Reactome:REACT_120752, GO:0043395=GO_REF:0000002, GO:0001523=Reactome:REACT_24968, GO:0006024=Reactome:REACT_121248, GO:0032288=GO_REF:0000024, GO:0005887=PMID:2148568, GO:0043236=GO_REF:0000024, GO:0040037=GO_REF:0000024, GO:0045121=PMID:12732622, GO:0005768=GO_REF:0000039} P35052 Glypican-1 protein 20130301 {GO:0005886=TAS, GO:0007603=TAS, GO:0044281=TAS, GO:0031225=IEA, GO:0005615=IEA, GO:0014037=ISS, GO:0007411=TAS, GO:0030200=IDA, GO:0030204=TAS, GO:2001016=ISS, GO:0030203=TAS, GO:0043202=TAS, GO:0005507=IDA, GO:0017134=ISS, GO:0005796=TAS, GO:0005975=TAS, GO:0005578=ISS, GO:0006027=TAS, GO:0043395=IEA, GO:0001523=TAS, GO:0006024=TAS, GO:0032288=ISS, GO:0005887=TAS, GO:0043236=ISS, GO:0040037=ISS, GO:0045121=IDA, GO:0005768=IEA} Schwann cell differentiation, axon guidance, carbohydrate metabolic process, chondroitin sulfate metabolic process, glycosaminoglycan biosynthetic process, glycosaminoglycan catabolic process, glycosaminoglycan metabolic process, heparan sulfate proteoglycan catabolic process, myelin assembly, negative regulation of fibroblast growth factor receptor signaling pathway, phototransduction, visible light, positive regulation of skeletal muscle cell differentiation, retinoid metabolic process, small molecule metabolic process Golgi lumen, anchored to membrane, endosome, extracellular space, integral to plasma membrane, lysosomal lumen, membrane raft, plasma membrane, proteinaceous extracellular matrix copper ion binding, fibroblast growth factor binding, heparan sulfate proteoglycan binding, laminin binding Human GPC2 LIFEdb UniProtKB {GO:0005886=Reactome:REACT_160272, GO:0007603=Reactome:REACT_160125, GO:0005783=GO_REF:0000054, GO:0005796=Reactome:REACT_121320, GO:0005975=Reactome:REACT_474, GO:0005578=GO_REF:0000002, GO:0006027=Reactome:REACT_120752, GO:0043395=GO_REF:0000002, GO:0044281=Reactome:REACT_111217, GO:0031225=GO_REF:0000037, GO:0005615=GO_REF:0000039, GO:0001523=Reactome:REACT_24968, GO:0006024=Reactome:REACT_121248, GO:0007224=GO_REF:0000019, GO:0030182=GO_REF:0000019, GO:0030204=Reactome:REACT_121206, GO:0030203=Reactome:REACT_121408, GO:0043202=Reactome:REACT_121392} Q8N158 Glypican-2 protein 20100607 {GO:0005886=TAS, GO:0007603=TAS, GO:0005783=IDA, GO:0005796=TAS, GO:0005975=TAS, GO:0005578=IEA, GO:0006027=TAS, GO:0043395=IEA, GO:0044281=TAS, GO:0031225=IEA, GO:0005615=IEA, GO:0001523=TAS, GO:0006024=TAS, GO:0007224=IEA, GO:0030182=IEA, GO:0030204=TAS, GO:0030203=TAS, GO:0043202=TAS} carbohydrate metabolic process, chondroitin sulfate metabolic process, glycosaminoglycan biosynthetic process, glycosaminoglycan catabolic process, glycosaminoglycan metabolic process, neuron differentiation, phototransduction, visible light, retinoid metabolic process, small molecule metabolic process, smoothened signaling pathway Golgi lumen, anchored to membrane, endoplasmic reticulum, extracellular space, lysosomal lumen, plasma membrane, proteinaceous extracellular matrix heparan sulfate proteoglycan binding Human GPC3 Reactome UniProtKB {GO:0005515=PMID:17549790, GO:0045732=GO_REF:0000019, GO:0001658=GO_REF:0000019, GO:0007603=Reactome:REACT_160125, GO:0005886=Reactome:REACT_160272, GO:0060422=PMID:17549790, GO:0030324=GO_REF:0000019, GO:0050680=GO_REF:0000019, GO:2000096=GO_REF:0000019, GO:0045879=GO_REF:0000019, GO:0044281=Reactome:REACT_111217, GO:0031225=GO_REF:0000037, GO:0030282=GO_REF:0000019, GO:0009653=PMID:8589713, GO:0005615=GO_REF:0000039, GO:0005764=GO_REF:0000019, GO:0072180=GO_REF:0000019, GO:0045807=GO_REF:0000019, GO:0030513=GO_REF:0000019, GO:0045880=GO_REF:0000019, GO:0060976=GO_REF:0000019, GO:0072138=GO_REF:0000024, GO:0009948=GO_REF:0000019, GO:0046326=GO_REF:0000019, GO:0030204=Reactome:REACT_121206, GO:0030203=Reactome:REACT_121408, GO:0046658=GO_REF:0000019, GO:0090090=GO_REF:0000019, GO:0045926=GO_REF:0000019, GO:0043202=Reactome:REACT_121392, GO:0010171=GO_REF:0000019, GO:0005975=Reactome:REACT_474, GO:0005796=Reactome:REACT_121320, GO:0030316=GO_REF:0000019, GO:0005578=GO_REF:0000002, GO:0006027=Reactome:REACT_120752, GO:0043395=GO_REF:0000002, GO:0001523=Reactome:REACT_24968, GO:0006024=Reactome:REACT_121248, GO:0072203=GO_REF:0000019, GO:0005887=PMID:7657705, GO:0035116=GO_REF:0000019} P51654 Glypican-3 protein 20130301 {GO:0005515=IPI, GO:0045732=IEA, GO:0001658=IEA, GO:0007603=TAS, GO:0005886=TAS, GO:0060422=IDA, GO:0030324=IEA, GO:0050680=IEA, GO:2000096=IEA, GO:0045879=IEA, GO:0044281=TAS, GO:0031225=IEA, GO:0030282=IEA, GO:0009653=TAS, GO:0005615=IEA, GO:0005764=IEA, GO:0072180=IEA, GO:0045807=IEA, GO:0030513=IEA, GO:0045880=IEA, GO:0060976=IEA, GO:0072138=ISS, GO:0009948=IEA, GO:0046326=IEA, GO:0030204=TAS, GO:0030203=TAS, GO:0046658=IEA, GO:0090090=IEA, GO:0045926=IEA, GO:0043202=TAS, GO:0010171=IEA, GO:0005975=TAS, GO:0005796=TAS, GO:0030316=IEA, GO:0005578=IEA, GO:0006027=TAS, GO:0043395=IEA, GO:0001523=TAS, GO:0006024=TAS, GO:0072203=IEA, GO:0005887=TAS, GO:0035116=IEA} anatomical structure morphogenesis, anterior/posterior axis specification, body morphogenesis, bone mineralization, branching involved in ureteric bud morphogenesis, carbohydrate metabolic process, cell proliferation involved in metanephros development, chondroitin sulfate metabolic process, coronary vasculature development, embryonic hindlimb morphogenesis, glycosaminoglycan biosynthetic process, glycosaminoglycan catabolic process, glycosaminoglycan metabolic process, lung development, mesenchymal cell proliferation involved in ureteric bud development, mesonephric duct morphogenesis, negative regulation of canonical Wnt receptor signaling pathway, negative regulation of epithelial cell proliferation, negative regulation of growth, negative regulation of smoothened signaling pathway, osteoclast differentiation, phototransduction, visible light, positive regulation of BMP signaling pathway, positive regulation of Wnt receptor signaling pathway, planar cell polarity pathway, positive regulation of endocytosis, positive regulation of glucose import, positive regulation of protein catabolic process, positive regulation of smoothened signaling pathway, retinoid metabolic process, small molecule metabolic process Golgi lumen, anchored to membrane, anchored to plasma membrane, extracellular space, integral to plasma membrane, lysosomal lumen, lysosome, plasma membrane, proteinaceous extracellular matrix heparan sulfate proteoglycan binding, peptidyl-dipeptidase inhibitor activity, protein binding Human GPC4 Reactome UniProtKB {GO:0007603=Reactome:REACT_160125, GO:0005886=Reactome:REACT_160272, GO:0008283=PMID:9787072, GO:0005796=Reactome:REACT_121320, GO:0005975=Reactome:REACT_474, GO:0005578=GO_REF:0000002, GO:0006027=Reactome:REACT_120752, GO:0043395=GO_REF:0000002, GO:0044281=Reactome:REACT_111217, GO:0031225=GO_REF:0000037, GO:0005615=GO_REF:0000039, GO:0009653=PMID:9787072, GO:0001523=Reactome:REACT_24968, GO:0006024=Reactome:REACT_121248, GO:0005887=PMID:9931407, GO:0030204=Reactome:REACT_121206, GO:0030203=Reactome:REACT_121408, GO:0009897=PMID:10585884, GO:0043202=Reactome:REACT_121392} O75487 Glypican-4 protein 20130301 {GO:0007603=TAS, GO:0005886=TAS, GO:0008283=TAS, GO:0005796=TAS, GO:0005975=TAS, GO:0005578=IEA, GO:0006027=TAS, GO:0043395=IEA, GO:0044281=TAS, GO:0031225=IEA, GO:0005615=IEA, GO:0009653=TAS, GO:0001523=TAS, GO:0006024=TAS, GO:0005887=TAS, GO:0030204=TAS, GO:0030203=TAS, GO:0009897=IDA, GO:0043202=TAS} anatomical structure morphogenesis, carbohydrate metabolic process, cell proliferation, chondroitin sulfate metabolic process, glycosaminoglycan biosynthetic process, glycosaminoglycan catabolic process, glycosaminoglycan metabolic process, phototransduction, visible light, retinoid metabolic process, small molecule metabolic process Golgi lumen, anchored to membrane, external side of plasma membrane, extracellular space, integral to plasma membrane, lysosomal lumen, plasma membrane, proteinaceous extracellular matrix heparan sulfate proteoglycan binding Human GPC5 Reactome UniProtKB {GO:0005886=Reactome:REACT_160272, GO:0007603=Reactome:REACT_160125, GO:0005796=Reactome:REACT_121320, GO:0005975=Reactome:REACT_474, GO:0005578=GO_REF:0000002, GO:0006027=Reactome:REACT_120752, GO:0043395=GO_REF:0000002, GO:0044281=Reactome:REACT_111217, GO:0031225=GO_REF:0000037, GO:0005615=GO_REF:0000039, GO:0001523=Reactome:REACT_24968, GO:0006024=Reactome:REACT_121248, GO:0005887=PMID:7657705, GO:0030204=Reactome:REACT_121206, GO:0030203=Reactome:REACT_121408, GO:0043202=Reactome:REACT_121392} P78333 Glypican-5 protein 20130301 {GO:0005886=TAS, GO:0007603=TAS, GO:0005796=TAS, GO:0005975=TAS, GO:0005578=IEA, GO:0006027=TAS, GO:0043395=IEA, GO:0044281=TAS, GO:0031225=IEA, GO:0005615=IEA, GO:0001523=TAS, GO:0006024=TAS, GO:0005887=TAS, GO:0030204=TAS, GO:0030203=TAS, GO:0043202=TAS} carbohydrate metabolic process, chondroitin sulfate metabolic process, glycosaminoglycan biosynthetic process, glycosaminoglycan catabolic process, glycosaminoglycan metabolic process, phototransduction, visible light, retinoid metabolic process, small molecule metabolic process Golgi lumen, anchored to membrane, extracellular space, integral to plasma membrane, lysosomal lumen, plasma membrane, proteinaceous extracellular matrix heparan sulfate proteoglycan binding Human GPCPD1 Reactome UniProtKB {GO:0006629=GO_REF:0000002, GO:0044281=Reactome:REACT_111217, GO:0006644=Reactome:REACT_120977, GO:0047389=GO_REF:0000003, GO:2001070=GO_REF:0000002, GO:0008889=GO_REF:0000002, GO:0006071=GO_REF:0000002, GO:0046474=Reactome:REACT_121401, GO:0005829=GO_REF:0000039} Q9NPB8 Glycerophosphocholine phosphodiesterase GPCPD1 protein 20130301 {GO:0006629=IEA, GO:0044281=TAS, GO:0006644=TAS, GO:0047389=IEA, GO:2001070=IEA, GO:0008889=IEA, GO:0006071=IEA, GO:0046474=TAS, GO:0005829=IEA} glycerol metabolic process, glycerophospholipid biosynthetic process, lipid metabolic process, phospholipid metabolic process, small molecule metabolic process cytosol glycerophosphocholine phosphodiesterase activity, glycerophosphodiester phosphodiesterase activity, starch binding Human GPD1 HPA UniProtKB {GO:0009331=GO_REF:0000002, GO:0004368=GO_REF:0000019, GO:0006094=GO_REF:0000019, GO:0004367=GO_REF:0000003, GO:0044281=Reactome:REACT_111217, GO:0042803=GO_REF:0000002, GO:0046168=GO_REF:0000002, GO:0005829=Reactome:REACT_1146, GO:0005739=GO_REF:0000019, GO:0005737=GO_REF:0000052, GO:0051287=GO_REF:0000019, GO:0006116=GO_REF:0000019, GO:0071356=GO_REF:0000019, GO:0019432=Reactome:REACT_1190, GO:0006644=Reactome:REACT_120870, GO:0071320=GO_REF:0000019, GO:0006654=Reactome:REACT_120906, GO:0044255=Reactome:REACT_22279, GO:0046474=Reactome:REACT_121401} P21695 "Glycerol-3-phosphate dehydrogenase ""NAD(+)"", cytoplasmic" protein 20111111 {GO:0009331=IEA, GO:0004368=IEA, GO:0006094=IEA, GO:0004367=IEA, GO:0044281=TAS, GO:0042803=IEA, GO:0046168=IEA, GO:0005829=TAS, GO:0005739=IEA, GO:0005737=IDA, GO:0051287=IEA, GO:0006116=IEA, GO:0071356=IEA, GO:0019432=TAS, GO:0006644=TAS, GO:0071320=IEA, GO:0006654=TAS, GO:0044255=TAS, GO:0046474=TAS} NADH oxidation, cellular lipid metabolic process, cellular response to cAMP, cellular response to tumor necrosis factor, gluconeogenesis, glycerol-3-phosphate catabolic process, glycerophospholipid biosynthetic process, phosphatidic acid biosynthetic process, phospholipid metabolic process, small molecule metabolic process, triglyceride biosynthetic process cytoplasm, cytosol, glycerol-3-phosphate dehydrogenase complex, mitochondrion "NAD binding, glycerol-3-phosphate dehydrogenase NAD+"" activity, glycerol-3-phosphate dehydrogenase activity, protein homodimerization activity""" Human GPD1L HPA UniProtKB {GO:0005886=PMID:17967977, GO:0019674=PMID:19745168, GO:0044281=Reactome:REACT_111217, GO:0042803=GO_REF:0000002, GO:0005829=Reactome:REACT_1146, GO:0046168=GO_REF:0000002, GO:0005737=GO_REF:0000052, GO:0060373=PMID:17967977, GO:0051287=GO_REF:0000002, GO:0090038=PMID:19666841, GO:0010765=PMID:19745168, GO:0019432=Reactome:REACT_1190, GO:2000010=PMID:17967977, GO:0006654=Reactome:REACT_120906, GO:0044255=Reactome:REACT_22279, GO:0086005=PMID:17967977, GO:0009331=GO_REF:0000002, GO:0005975=GO_REF:0000002, GO:0004367=GO_REF:0000003, GO:2000649=PMID:17967977, GO:0006734=GO_REF:0000019, GO:0044325=PMID:19666841, GO:0002027=PMID:17967977, GO:0006644=Reactome:REACT_120870, GO:0046474=Reactome:REACT_121401, GO:0017080=PMID:17967977} Q8N335 Glycerol-3-phosphate dehydrogenase 1-like protein protein 20101115 {GO:0005886=IDA, GO:0019674=IMP, GO:0044281=TAS, GO:0042803=IEA, GO:0005829=TAS, GO:0046168=IEA, GO:0005737=IDA, GO:0060373=IMP, GO:0051287=IEA, GO:0090038=IMP, GO:0010765=IMP, GO:0019432=TAS, GO:2000010=IMP, GO:0006654=TAS, GO:0044255=TAS, GO:0086005=IMP, GO:0009331=IEA, GO:0005975=IEA, GO:0004367=IEA, GO:2000649=IMP, GO:0006734=IEA, GO:0044325=IPI, GO:0002027=IMP, GO:0006644=TAS, GO:0046474=TAS, GO:0017080=IMP} NAD metabolic process, NADH metabolic process, carbohydrate metabolic process, cellular lipid metabolic process, glycerol-3-phosphate catabolic process, glycerophospholipid biosynthetic process, negative regulation of protein kinase C signaling cascade, phosphatidic acid biosynthetic process, phospholipid metabolic process, positive regulation of protein localization to cell surface, positive regulation of sodium ion transport, regulation of heart rate, regulation of sodium ion transmembrane transporter activity, regulation of ventricular cardiac muscle cell action potential, regulation of ventricular cardiac muscle cell membrane depolarization, small molecule metabolic process, triglyceride biosynthetic process cytoplasm, cytosol, glycerol-3-phosphate dehydrogenase complex, plasma membrane "NAD binding, glycerol-3-phosphate dehydrogenase NAD+"" activity, ion channel binding, protein homodimerization activity, sodium channel regulator activity""" Human GPD2 Reactome UniProtKB {GO:0009331=GO_REF:0000002, GO:0052591=GO_REF:0000003, GO:0019563=GO_REF:0000041, GO:0005509=GO_REF:0000002, GO:0006094=GO_REF:0000019, GO:0005743=Reactome:REACT_16938, GO:0004368=PMID:9070847, GO:0044281=Reactome:REACT_111217, GO:0006072=GO_REF:0000019, GO:0044255=Reactome:REACT_22279} P43304 Glycerol-3-phosphate dehydrogenase, mitochondrial protein 20130301 {GO:0009331=IEA, GO:0052591=IEA, GO:0019563=IEA, GO:0005509=IEA, GO:0006094=IEA, GO:0005743=TAS, GO:0004368=TAS, GO:0044281=TAS, GO:0006072=IEA, GO:0044255=TAS} cellular lipid metabolic process, gluconeogenesis, glycerol catabolic process, glycerol-3-phosphate metabolic process, small molecule metabolic process glycerol-3-phosphate dehydrogenase complex, mitochondrial inner membrane calcium ion binding, glycerol-3-phosphate dehydrogenase activity, sn-glycerol-3-phosphate:ubiquinone-8 oxidoreductase activity Human GPHA2 MGI UniProtKB {GO:0005179=GO_REF:0000037, GO:0005576=PMID:12089349} Q96T91 Glycoprotein hormone alpha-2 protein 20021024 {GO:0005179=IEA, GO:0005576=IDA} extracellular region hormone activity Human GPHB5 UniProtKB UniProtKB {GO:0005179=GO_REF:0000037, GO:0005576=GO_REF:0000039} Q86YW7 Glycoprotein hormone beta-5 protein 20130413 {GO:0005179=IEA, GO:0005576=IEA} extracellular region hormone activity Human UniProtKB-SubCell:SL-0243 GPHN Reactome UniProtKB {GO:0030054=GO_REF:0000037, GO:0005886=Reactome:REACT_25050, GO:0006767=Reactome:REACT_11238, GO:0044281=Reactome:REACT_111217, GO:0005524=GO_REF:0000037, GO:0046872=GO_REF:0000037, GO:0032324=Reactome:REACT_25073, GO:0005737=GO_REF:0000037, GO:0007529=GO_REF:0000019, GO:0006766=Reactome:REACT_11193, GO:0045211=GO_REF:0000039, GO:0006777=GO_REF:0000037, GO:0005856=GO_REF:0000039, GO:0016740=Reactome:REACT_25050} Q9NQX3 Gephyrin protein 20101105 {GO:0030054=IEA, GO:0005886=TAS, GO:0006767=TAS, GO:0044281=TAS, GO:0005524=IEA, GO:0046872=IEA, GO:0032324=TAS, GO:0005737=IEA, GO:0007529=IEA, GO:0006766=TAS, GO:0045211=IEA, GO:0006777=IEA, GO:0005856=IEA, GO:0016740=TAS} Mo-molybdopterin cofactor biosynthetic process, establishment of synaptic specificity at neuromuscular junction, molybdopterin cofactor biosynthetic process, small molecule metabolic process, vitamin metabolic process, water-soluble vitamin metabolic process cell junction, cytoplasm, cytoskeleton, plasma membrane, postsynaptic membrane ATP binding, metal ion binding, transferase activity Human GPI HPA UniProtKB {GO:0043005=GO_REF:0000019, GO:0019242=GO_REF:0000019, GO:0005886=GO_REF:0000052, GO:0046185=GO_REF:0000019, GO:0006094=Reactome:REACT_1520, GO:0005634=GO_REF:0000052, GO:0004347=Reactome:REACT_1690, GO:0044281=Reactome:REACT_111217, GO:0005615=GO_REF:0000037, GO:0006096=Reactome:REACT_1383, GO:0005829=Reactome:REACT_1690, GO:0043524=GO_REF:0000019, GO:0005737=GO_REF:0000052, GO:0006959=PMID:3020690, GO:0016866=GO_REF:0000019, GO:0007611=GO_REF:0000019, GO:0006006=Reactome:REACT_723, GO:0043154=GO_REF:0000019, GO:0051156=GO_REF:0000019, GO:0005975=Reactome:REACT_474, GO:0005730=GO_REF:0000052, GO:0001525=GO_REF:0000037, GO:0005125=GO_REF:0000037, GO:0007599=PMID:7435496, GO:0048029=GO_REF:0000019, GO:0008083=GO_REF:0000037} P06744 Glucose-6-phosphate isomerase protein 20101115 {GO:0043005=IEA, GO:0019242=IEA, GO:0005886=IDA, GO:0046185=IEA, GO:0006094=TAS, GO:0005634=IDA, GO:0004347=TAS, GO:0044281=TAS, GO:0005615=IEA, GO:0006096=TAS, GO:0005829=TAS, GO:0043524=IEA, GO:0005737=IDA, GO:0006959=TAS, GO:0016866=IEA, GO:0007611=IEA, GO:0006006=TAS, GO:0043154=IEA, GO:0051156=IEA, GO:0005975=TAS, GO:0005730=IDA, GO:0001525=IEA, GO:0005125=IEA, GO:0007599=TAS, GO:0048029=IEA, GO:0008083=IEA} aldehyde catabolic process, angiogenesis, carbohydrate metabolic process, gluconeogenesis, glucose 6-phosphate metabolic process, glucose metabolic process, glycolysis, hemostasis, humoral immune response, learning or memory, methylglyoxal biosynthetic process, negative regulation of cysteine-type endopeptidase activity involved in apoptotic process, negative regulation of neuron apoptotic process, small molecule metabolic process cytoplasm, cytosol, extracellular space, neuron projection, nucleolus, nucleus, plasma membrane cytokine activity, glucose-6-phosphate isomerase activity, growth factor activity, intramolecular transferase activity, monosaccharide binding Human GPKOW HPA UniProtKB {GO:0005515=PMID:21880142, GO:0008150=GO_REF:0000015, GO:0003674=GO_REF:0000015, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0003676=GO_REF:0000002} Q92917 G patch domain and KOW motifs-containing protein protein 20101115 {GO:0005515=IPI, GO:0008150=ND, GO:0003674=ND, GO:0005730=IDA, GO:0005634=IDA, GO:0003676=IEA} biological_process nucleolus, nucleus molecular_function, nucleic acid binding, protein binding NOT Human GPLD1 UniProtKB UniProtKB {GO:0008286=PMID:18328347, GO:0008285=PMID:19135435, GO:0051047=GO_REF:0000024, GO:0002042=PMID:17720976, GO:0010897=GO_REF:0000024, GO:0005615=PMID:17761367, GO:0071467=PMID:17761367, GO:0010907=GO_REF:0000024, GO:0010983=GO_REF:0000024, GO:0005737=GO_REF:0000024, GO:0071397=PMID:17761367, GO:0002062=GO_REF:0000024, GO:0035701=PMID:17368745, GO:0071277=PMID:2760042, GO:0006507=PMID:2760042, GO:0070633=GO_REF:0000024, GO:0032869=PMID:15907827, GO:0010867=GO_REF:0000024, GO:0043065=PMID:19135435, GO:0035774=GO_REF:0000024, GO:1900076=PMID:18328347, GO:0005578=GO_REF:0000024, GO:0004621=PMID:2760042, GO:0009749=PMID:15907827, GO:0010595=PMID:17720976, GO:0071401=PMID:17761367, GO:0001503=GO_REF:0000024, GO:0045919=PMID:19135435, GO:0010694=GO_REF:0000024, GO:0046470=PMID:2017684, GO:0002430=PMID:19135435, GO:0097241=PMID:17368745, GO:0017080=GO_REF:0000024} P80108 Phosphatidylinositol-glycan-specific phospholipase D protein 20120131 {GO:0008286=IDA, GO:0008285=IDA, GO:0051047=ISS, GO:0002042=IMP, GO:0010897=ISS, GO:0005615=IDA, GO:0071467=IDA, GO:0010907=ISS, GO:0010983=ISS, GO:0005737=ISS, GO:0071397=IMP, GO:0002062=ISS, GO:0035701=TAS, GO:0071277=IDA, GO:0006507=IDA, GO:0070633=ISS, GO:0032869=IDA, GO:0010867=ISS, GO:0043065=IDA, GO:0035774=ISS, GO:1900076=IDA, GO:0005578=ISS, GO:0004621=IDA, GO:0009749=IDA, GO:0010595=IMP, GO:0071401=IMP, GO:0001503=ISS, GO:0045919=IDA, GO:0010694=ISS, GO:0046470=TAS, GO:0002430=IDA, GO:0097241=TAS, GO:0017080=ISS} GPI anchor release, cell migration involved in sprouting angiogenesis, cellular response to calcium ion, cellular response to cholesterol, cellular response to insulin stimulus, cellular response to pH, cellular response to triglyceride, chondrocyte differentiation, complement receptor mediated signaling pathway, hematopoietic stem cell migration, hematopoietic stem cell migration to bone marrow, insulin receptor signaling pathway, negative regulation of cell proliferation, negative regulation of triglyceride catabolic process, ossification, phosphatidylcholine metabolic process, positive regulation of alkaline phosphatase activity, positive regulation of apoptotic process, positive regulation of cytolysis, positive regulation of endothelial cell migration, positive regulation of glucose metabolic process, positive regulation of high-density lipoprotein particle clearance, positive regulation of insulin secretion involved in cellular response to glucose stimulus, positive regulation of secretion, positive regulation of triglyceride biosynthetic process, regulation of cellular response to insulin stimulus, response to glucose stimulus, transepithelial transport cytoplasm, extracellular space, proteinaceous extracellular matrix glycosylphosphatidylinositol phospholipase D activity, sodium channel regulator activity Human GPM6A UniProtKB UniProtKB {GO:0043005=GO_REF:0000024, GO:0005262=GO_REF:0000019, GO:0003407=GO_REF:0000024, GO:0005886=GO_REF:0000024, GO:0009986=PMID:12493773, GO:0051491=GO_REF:0000024, GO:0030175=GO_REF:0000024, GO:0044295=GO_REF:0000024, GO:0007416=GO_REF:0000024, GO:0048863=PMID:19298174, GO:0043197=GO_REF:0000039, GO:0048812=GO_REF:0000024, GO:0043025=GO_REF:0000024, GO:0016021=GO_REF:0000037, GO:0001764=PMID:19298174} P51674 Neuronal membrane glycoprotein M6-a protein 20120503 {GO:0043005=ISS, GO:0005262=IEA, GO:0003407=ISS, GO:0005886=ISS, GO:0009986=IDA, GO:0051491=ISS, GO:0030175=ISS, GO:0044295=ISS, GO:0007416=ISS, GO:0048863=IDA, GO:0043197=IEA, GO:0048812=ISS, GO:0043025=ISS, GO:0016021=IEA, GO:0001764=IDA} neural retina development, neuron migration, neuron projection morphogenesis, positive regulation of filopodium assembly, stem cell differentiation, synapse assembly axonal growth cone, cell surface, dendritic spine, filopodium, integral to membrane, neuron projection, neuronal cell body, plasma membrane calcium channel activity Human UniProtKB:Q812E9 GPM6B UniProtKB UniProtKB {GO:0030501=PMID:21638316, GO:0005886=GO_REF:0000024, GO:0015031=GO_REF:0000037, GO:0051893=PMID:21638316, GO:0030154=GO_REF:0000037, GO:0007399=PMID:8661015, GO:2000009=GO_REF:0000024, GO:0003674=GO_REF:0000015, GO:0085029=PMID:21638316, GO:0001503=GO_REF:0000037, GO:0051612=GO_REF:0000024, GO:0032956=PMID:21638316, GO:0045121=GO_REF:0000024, GO:0016021=GO_REF:0000029} Q13491 Neuronal membrane glycoprotein M6-b protein 20120503 {GO:0030501=IMP, GO:0005886=ISS, GO:0015031=IEA, GO:0051893=IMP, GO:0030154=IEA, GO:0007399=NAS, GO:2000009=ISS, GO:0003674=ND, GO:0085029=IMP, GO:0001503=IEA, GO:0051612=ISS, GO:0032956=IMP, GO:0045121=ISS, GO:0016021=NAS} cell differentiation, extracellular matrix assembly, negative regulation of protein localization to cell surface, negative regulation of serotonin uptake, nervous system development, ossification, positive regulation of bone mineralization, protein transport, regulation of actin cytoskeleton organization, regulation of focal adhesion assembly integral to membrane, membrane raft, plasma membrane molecular_function Human GPN1 HPA UniProtKB {GO:0005737=GO_REF:0000039, GO:0017111=GO_REF:0000002, GO:0000166=GO_REF:0000002, GO:0005525=GO_REF:0000037, GO:0043231=GO_REF:0000052} Q9HCN4 GPN-loop GTPase 1 protein 20110516 {GO:0005737=IEA, GO:0017111=IEA, GO:0000166=IEA, GO:0005525=IEA, GO:0043231=IDA} cytoplasm, intracellular membrane-bounded organelle GTP binding, nucleoside-triphosphatase activity, nucleotide binding Human GPN2 UniProtKB UniProtKB {GO:0008150=GO_REF:0000015, GO:0003674=GO_REF:0000015, GO:0000166=GO_REF:0000002, GO:0005575=GO_REF:0000015, GO:0005525=GO_REF:0000037} Q9H9Y4 GPN-loop GTPase 2 protein 20080610 {GO:0008150=ND, GO:0003674=ND, GO:0000166=IEA, GO:0005575=ND, GO:0005525=IEA} biological_process cellular_component GTP binding, molecular_function, nucleotide binding Human GPN3 LIFEdb UniProtKB {GO:0043234=GO_REF:0000054, GO:0000166=GO_REF:0000002, GO:0005525=GO_REF:0000037} Q9UHW5 GPN-loop GTPase 3 protein 20100607 {GO:0043234=IDA, GO:0000166=IEA, GO:0005525=IEA} protein complex GTP binding, nucleotide binding Human GPNMB UniProtKB UniProtKB {GO:0042470=GO_REF:0000039, GO:0008285=PMID:7814155, GO:0005178=GO_REF:0000019, GO:0005887=GO_REF:0000019, GO:0016021=GO_REF:0000038, GO:0030282=GO_REF:0000019, GO:0007155=GO_REF:0000019, GO:0008201=GO_REF:0000019, GO:0001649=GO_REF:0000019} Q96F58 Glycoprotein (Transmembrane) nmb protein 20130413 {GO:0042470=IEA, GO:0008285=TAS, GO:0005178=IEA, GO:0005887=IEA, GO:0016021=IEA, GO:0030282=IEA, GO:0007155=IEA, GO:0008201=IEA, GO:0001649=IEA} bone mineralization, cell adhesion, negative regulation of cell proliferation, osteoblast differentiation integral to membrane, integral to plasma membrane, melanosome heparin binding, integrin binding Human UniProtKB-KW:KW-0812 GPR1 PINC UniProtKB {GO:0007186=PMID:7851889, GO:0005887=PMID:7851889, GO:0004930=GO_REF:0000037, GO:0016021=GO_REF:0000002} P46091 G-protein coupled receptor 1 protein 20030904 {GO:0007186=TAS, GO:0005887=TAS, GO:0004930=IEA, GO:0016021=IEA} G-protein coupled receptor signaling pathway integral to membrane, integral to plasma membrane G-protein coupled receptor activity Human GPR107 UniProtKB UniProtKB {GO:0016021=GO_REF:0000037} Q5VW38 Protein GPR107 protein 20130413 {GO:0016021=IEA} integral to membrane Human UniProtKB-KW:KW-0812 GPR108 UniProtKB UniProtKB {GO:0016021=GO_REF:0000037} Q9NPR9 Protein GPR108 protein 20130413 {GO:0016021=IEA} integral to membrane Human UniProtKB-KW:KW-0812 GPR113 GDB UniProtKB {GO:0007186=PMID:15203201, GO:0005886=GO_REF:0000039, GO:0004930=GO_REF:0000037, GO:0007218=GO_REF:0000002, GO:0016021=GO_REF:0000037} Q8IZF5 Probable G-protein coupled receptor 113 protein 20050506 {GO:0007186=TAS, GO:0005886=IEA, GO:0004930=IEA, GO:0007218=IEA, GO:0016021=IEA} G-protein coupled receptor signaling pathway, neuropeptide signaling pathway integral to membrane, plasma membrane G-protein coupled receptor activity Human GPR115 GDB UniProtKB {GO:0007186=PMID:15203201, GO:0005886=GO_REF:0000039, GO:0004930=GO_REF:0000037, GO:0007218=GO_REF:0000002, GO:0016021=GO_REF:0000037} Q8IZF3 Probable G-protein coupled receptor 115 protein 20050506 {GO:0007186=TAS, GO:0005886=IEA, GO:0004930=IEA, GO:0007218=IEA, GO:0016021=IEA} G-protein coupled receptor signaling pathway, neuropeptide signaling pathway integral to membrane, plasma membrane G-protein coupled receptor activity Human GPR119 UniProtKB UniProtKB {GO:0005886=GO_REF:0000039, GO:0004930=GO_REF:0000037, GO:0031210=GO_REF:0000019, GO:0016021=GO_REF:0000037, GO:0030073=GO_REF:0000019} Q8TDV5 Glucose-dependent insulinotropic receptor protein 20130413 {GO:0005886=IEA, GO:0004930=IEA, GO:0031210=IEA, GO:0016021=IEA, GO:0030073=IEA} insulin secretion integral to membrane, plasma membrane G-protein coupled receptor activity, phosphatidylcholine binding Human UniProtKB-SubCell:SL-0039 GPR12 PINC UniProtKB {GO:0007186=PMID:8530049, GO:0005887=PMID:8530049, GO:0004930=GO_REF:0000037, GO:0006874=GO_REF:0000019, GO:0031210=GO_REF:0000019} P47775 G-protein coupled receptor 12 protein 20030904 {GO:0007186=TAS, GO:0005887=TAS, GO:0004930=IEA, GO:0006874=IEA, GO:0031210=IEA} G-protein coupled receptor signaling pathway, cellular calcium ion homeostasis integral to plasma membrane G-protein coupled receptor activity, phosphatidylcholine binding Human GPR124 GDB UniProtKB {GO:0007186=PMID:15203201, GO:0005886=GO_REF:0000039, GO:0050920=GO_REF:0000024, GO:0043542=GO_REF:0000024, GO:0004930=GO_REF:0000037, GO:0007218=GO_REF:0000002, GO:0045765=GO_REF:0000024, GO:0002040=GO_REF:0000024, GO:0016021=GO_REF:0000037, GO:0007417=GO_REF:0000024} Q96PE1 G-protein coupled receptor 124 protein 20050504 {GO:0007186=TAS, GO:0005886=IEA, GO:0050920=ISS, GO:0043542=ISS, GO:0004930=IEA, GO:0007218=IEA, GO:0045765=ISS, GO:0002040=ISS, GO:0016021=IEA, GO:0007417=ISS} G-protein coupled receptor signaling pathway, central nervous system development, endothelial cell migration, neuropeptide signaling pathway, regulation of angiogenesis, regulation of chemotaxis, sprouting angiogenesis integral to membrane, plasma membrane G-protein coupled receptor activity Human GPR125 GDB UniProtKB {GO:0007186=PMID:15203201, GO:0004930=GO_REF:0000037, GO:0007218=GO_REF:0000002, GO:0016021=GO_REF:0000037, GO:0009897=GO_REF:0000019} Q8IWK6 Probable G-protein coupled receptor 125 protein 20050504 {GO:0007186=TAS, GO:0004930=IEA, GO:0007218=IEA, GO:0016021=IEA, GO:0009897=IEA} G-protein coupled receptor signaling pathway, neuropeptide signaling pathway external side of plasma membrane, integral to membrane G-protein coupled receptor activity Human GPR126 GDB UniProtKB {GO:0007186=PMID:15203201, GO:0005886=GO_REF:0000039, GO:0004930=GO_REF:0000037, GO:0007218=GO_REF:0000002, GO:0016021=GO_REF:0000037} Q86SQ4 G-protein coupled receptor 126 protein 20050510 {GO:0007186=TAS, GO:0005886=IEA, GO:0004930=IEA, GO:0007218=IEA, GO:0016021=IEA} G-protein coupled receptor signaling pathway, neuropeptide signaling pathway integral to membrane, plasma membrane G-protein coupled receptor activity Human GPR135 UniProtKB UniProtKB {GO:0005886=GO_REF:0000039, GO:0004930=GO_REF:0000037, GO:0016021=GO_REF:0000037} Q8IZ08 Probable G-protein coupled receptor 135 protein 20130413 {GO:0005886=IEA, GO:0004930=IEA, GO:0016021=IEA} integral to membrane, plasma membrane G-protein coupled receptor activity Human UniProtKB-SubCell:SL-0039 GPR142 HPA UniProtKB {GO:0005737=GO_REF:0000052, GO:0030054=GO_REF:0000052, GO:0005886=GO_REF:0000052, GO:0004930=GO_REF:0000037, GO:0016021=GO_REF:0000037} Q7Z601 Probable G-protein coupled receptor 142 protein 20101115 {GO:0005737=IDA, GO:0030054=IDA, GO:0005886=IDA, GO:0004930=IEA, GO:0016021=IEA} cell junction, cytoplasm, integral to membrane, plasma membrane G-protein coupled receptor activity Human GPR143 PINC UniProtKB {GO:0005515=PMID:19717472, GO:0033162=PMID:16621890, GO:0072544=PMID:18828673, GO:0072545=PMID:18828673, GO:0035584=PMID:18828673, GO:0006726=PMID:7647783, GO:0005886=PMID:16524428, GO:0032438=PMID:19717472, GO:0032400=PMID:19717472, GO:0005765=PMID:16621890, GO:0032402=PMID:19717472, GO:0016324=PMID:18828673, GO:0005737=PMID:10471510, GO:0050848=PMID:18828673, GO:0042470=PMID:10471510, GO:0005794=PMID:19717472, GO:0004930=PMID:16524428, GO:0048015=PMID:16524428, GO:0035240=PMID:18828673, GO:0007165=PMID:10471510, GO:0007186=PMID:16524428, GO:0016020=PMID:10471510, GO:0016021=GO_REF:0000037, GO:0035643=PMID:18828673, GO:0007601=PMID:7647783} P51810 G-protein coupled receptor 143 protein 20030904 {GO:0005515=IPI, GO:0033162=IDA, GO:0072544=IDA, GO:0072545=IDA, GO:0035584=IDA, GO:0006726=TAS, GO:0005886=IDA, GO:0032438=IMP, GO:0032400=IDA, GO:0005765=IDA, GO:0032402=IDA, GO:0016324=IDA, GO:0005737=TAS, GO:0050848=IDA, GO:0042470=IDA, GO:0005794=IDA, GO:0004930=IDA, GO:0048015=IDA, GO:0035240=IDA, GO:0007165=TAS, GO:0007186=IDA, GO:0016020=TAS, GO:0016021=IEA, GO:0035643=IDA, GO:0007601=TAS} G-protein coupled receptor signaling pathway, calcium-mediated signaling using intracellular calcium source, eye pigment biosynthetic process, melanosome localization, melanosome organization, melanosome transport, phosphatidylinositol-mediated signaling, regulation of calcium-mediated signaling, signal transduction, visual perception Golgi apparatus, apical plasma membrane, cytoplasm, integral to membrane, lysosomal membrane, melanosome, melanosome membrane, membrane, plasma membrane G-protein coupled receptor activity, L-DOPA binding, L-DOPA receptor activity, dopamine binding, protein binding, tyrosine binding Human GPR15 PINC UniProtKB {GO:0007186=PMID:8838812, GO:0004930=PMID:8838812, GO:0005887=PMID:8838812, GO:0045028=GO_REF:0000002} P49685 G-protein coupled receptor 15 protein 20030904 {GO:0007186=TAS, GO:0004930=TAS, GO:0005887=TAS, GO:0045028=IEA} G-protein coupled receptor signaling pathway integral to plasma membrane G-protein coupled purinergic nucleotide receptor activity, G-protein coupled receptor activity Human GPR151 UniProtKB UniProtKB {GO:0005886=GO_REF:0000039, GO:0004930=GO_REF:0000037, GO:0016021=GO_REF:0000037} Q8TDV0 Probable G-protein coupled receptor 151 protein 20130413 {GO:0005886=IEA, GO:0004930=IEA, GO:0016021=IEA} integral to membrane, plasma membrane G-protein coupled receptor activity Human UniProtKB-SubCell:SL-0039 GPR153 UniProtKB UniProtKB {GO:0005886=GO_REF:0000039, GO:0004930=GO_REF:0000037, GO:0016021=GO_REF:0000037} Q6NV75 Probable G-protein coupled receptor 153 protein 20130413 {GO:0005886=IEA, GO:0004930=IEA, GO:0016021=IEA} integral to membrane, plasma membrane G-protein coupled receptor activity Human UniProtKB-SubCell:SL-0039 GPR155 UniProtKB UniProtKB {GO:0035556=GO_REF:0000002, GO:0016021=GO_REF:0000037, GO:0055085=GO_REF:0000002} Q7Z3F1 Integral membrane protein GPR155 protein 20130413 {GO:0035556=IEA, GO:0016021=IEA, GO:0055085=IEA} intracellular signal transduction, transmembrane transport integral to membrane Human UniProtKB-KW:KW-0812 GPR158 UniProtKB UniProtKB {GO:0008277=GO_REF:0000019, GO:0005886=GO_REF:0000039, GO:0004930=GO_REF:0000037, GO:0016021=GO_REF:0000037, GO:0072659=GO_REF:0000019} Q5T848 Probable G-protein coupled receptor 158 protein 20130413 {GO:0008277=IEA, GO:0005886=IEA, GO:0004930=IEA, GO:0016021=IEA, GO:0072659=IEA} protein localization to plasma membrane, regulation of G-protein coupled receptor protein signaling pathway integral to membrane, plasma membrane G-protein coupled receptor activity Human UniProtKB-SubCell:SL-0039 GPR161 UniProtKB UniProtKB {GO:1901621=GO_REF:0000024, GO:0060170=GO_REF:0000039, GO:0007186=GO_REF:0000024, GO:0004930=GO_REF:0000024, GO:0030819=GO_REF:0000024, GO:0007275=GO_REF:0000037, GO:0072372=GO_REF:0000024, GO:0016021=GO_REF:0000037, GO:0055037=GO_REF:0000024} Q8N6U8 G-protein coupled receptor 161 protein 20130222 {GO:1901621=ISS, GO:0060170=IEA, GO:0007186=ISS, GO:0004930=ISS, GO:0030819=ISS, GO:0007275=IEA, GO:0072372=ISS, GO:0016021=IEA, GO:0055037=ISS} G-protein coupled receptor signaling pathway, multicellular organismal development, negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning, positive regulation of cAMP biosynthetic process cilium membrane, integral to membrane, primary cilium, recycling endosome G-protein coupled receptor activity Human UniProtKB:B2RPY5 GPR17 GOC UniProtKB {GO:0070098=PMID:8558062, GO:0005886=Reactome:REACT_22436, GO:0007186=PMID:8558062, GO:0005887=PMID:8558062, GO:0045028=GO_REF:0000002, GO:0004930=GO_REF:0000002, GO:0004950=PMID:8558062, GO:0016021=GO_REF:0000002} Q13304 Uracil nucleotide/cysteinyl leukotriene receptor protein 20130413 {GO:0070098=TAS, GO:0005886=TAS, GO:0007186=TAS, GO:0005887=TAS, GO:0045028=IEA, GO:0004930=IEA, GO:0004950=TAS, GO:0016021=IEA} G-protein coupled receptor signaling pathway, chemokine-mediated signaling pathway integral to membrane, integral to plasma membrane, plasma membrane G-protein coupled purinergic nucleotide receptor activity, G-protein coupled receptor activity, chemokine receptor activity Human GPR176 PINC UniProtKB {GO:0007186=PMID:7893747, GO:0005887=PMID:7893747, GO:0004930=GO_REF:0000037, GO:0007268=PMID:7893747, GO:0016021=GO_REF:0000002} Q14439 Probable G-protein coupled receptor 176 protein 20030904 {GO:0007186=TAS, GO:0005887=TAS, GO:0004930=IEA, GO:0007268=TAS, GO:0016021=IEA} G-protein coupled receptor signaling pathway, synaptic transmission integral to membrane, integral to plasma membrane G-protein coupled receptor activity Human GPR179 UniProtKB UniProtKB {GO:0005886=GO_REF:0000039, GO:0004930=GO_REF:0000037, GO:0044292=GO_REF:0000019, GO:0016021=GO_REF:0000037, GO:0007601=PMID:22325362, GO:0072659=GO_REF:0000019} Q6PRD1 Probable G-protein coupled receptor 179 protein 20120510 {GO:0005886=IEA, GO:0004930=IEA, GO:0044292=IEA, GO:0016021=IEA, GO:0007601=IMP, GO:0072659=IEA} protein localization to plasma membrane, visual perception dendrite terminus, integral to membrane, plasma membrane G-protein coupled receptor activity Human GPR180 UniProtKB UniProtKB {GO:0007186=GO_REF:0000002, GO:0016021=GO_REF:0000037, GO:0019236=GO_REF:0000002} Q86V85 Integral membrane protein GPR180 protein 20130413 {GO:0007186=IEA, GO:0016021=IEA, GO:0019236=IEA} G-protein coupled receptor signaling pathway, response to pheromone integral to membrane Human UniProtKB-KW:KW-0812 GPR182 PINC UniProtKB {GO:0005886=GO_REF:0000039, GO:0004930=GO_REF:0000037, GO:0016021=GO_REF:0000037, GO:0007166=PMID:9367907, GO:0004888=PMID:9367907} O15218 G-protein coupled receptor 182 protein 20030904 {GO:0005886=IEA, GO:0004930=IEA, GO:0016021=IEA, GO:0007166=TAS, GO:0004888=TAS} cell surface receptor signaling pathway integral to membrane, plasma membrane G-protein coupled receptor activity, transmembrane signaling receptor activity Human GPR183 PINC UniProtKB {GO:0006955=PMID:8383238, GO:0008142=PMID:21796212, GO:0007186=PMID:21673108, GO:0005886=PMID:21673108, GO:0005887=PMID:8383238, GO:0004930=PMID:8383238, GO:0030890=PMID:21673108, GO:0045028=GO_REF:0000002, GO:0006959=GO_REF:0000024, GO:0070374=PMID:21673108, GO:0002313=GO_REF:0000024} P32249 G-protein coupled receptor 183 protein 20030904 {GO:0006955=TAS, GO:0008142=IDA, GO:0007186=IDA, GO:0005886=IDA, GO:0005887=TAS, GO:0004930=TAS, GO:0030890=IDA, GO:0045028=IEA, GO:0006959=ISS, GO:0070374=IDA, GO:0002313=ISS} G-protein coupled receptor signaling pathway, humoral immune response, immune response, mature B cell differentiation involved in immune response, positive regulation of B cell proliferation, positive regulation of ERK1 and ERK2 cascade integral to plasma membrane, plasma membrane G-protein coupled purinergic nucleotide receptor activity, G-protein coupled receptor activity, oxysterol binding Human GPR20 UniProtKB UniProtKB {GO:0007186=PMID:9073069, GO:0004930=PMID:18347022, GO:0005887=PMID:18347022} Q99678 G-protein coupled receptor 20 protein 20091202 {GO:0007186=IDA, GO:0004930=IDA, GO:0005887=IDA} G-protein coupled receptor signaling pathway integral to plasma membrane G-protein coupled receptor activity Human GPR21 PINC UniProtKB {GO:0007186=PMID:9073069, GO:0005887=PMID:9073069, GO:0004930=GO_REF:0000037} Q99679 Probable G-protein coupled receptor 21 protein 20030904 {GO:0007186=TAS, GO:0005887=TAS, GO:0004930=IEA} G-protein coupled receptor signaling pathway integral to plasma membrane G-protein coupled receptor activity Human GPR22 PINC UniProtKB {GO:0007186=PMID:9073069, GO:0005887=PMID:9073069, GO:0004930=GO_REF:0000037} Q99680 Probable G-protein coupled receptor 22 protein 20030904 {GO:0007186=TAS, GO:0005887=TAS, GO:0004930=IEA} G-protein coupled receptor signaling pathway integral to plasma membrane G-protein coupled receptor activity Human GPR25 PINC UniProtKB {GO:0007186=PMID:9020062, GO:0005887=PMID:9020062, GO:0004930=GO_REF:0000037} O00155 Probable G-protein coupled receptor 25 protein 20030904 {GO:0007186=TAS, GO:0005887=TAS, GO:0004930=IEA} G-protein coupled receptor signaling pathway integral to plasma membrane G-protein coupled receptor activity Human GPR26 UniProtKB UniProtKB {GO:0005886=GO_REF:0000039, GO:0004930=PMID:17363172, GO:0007189=PMID:17363172, GO:0016021=GO_REF:0000037} Q8NDV2 G-protein coupled receptor 26 protein 20100201 {GO:0005886=IEA, GO:0004930=IDA, GO:0007189=IDA, GO:0016021=IEA} adenylate cyclase-activating G-protein coupled receptor signaling pathway integral to membrane, plasma membrane G-protein coupled receptor activity Human GPR3 PINC UniProtKB {GO:0040020=GO_REF:0000019, GO:0005887=PMID:7639700, GO:0004930=GO_REF:0000037, GO:0007189=PMID:7639700} P46089 G-protein coupled receptor 3 protein 20030904 {GO:0040020=IEA, GO:0005887=TAS, GO:0004930=IEA, GO:0007189=TAS} adenylate cyclase-activating G-protein coupled receptor signaling pathway, regulation of meiosis integral to plasma membrane G-protein coupled receptor activity Human GPR37 PINC UniProtKB {GO:0007186=PMID:9144577, GO:0005887=PMID:9144577, GO:0004930=GO_REF:0000037, GO:0005789=GO_REF:0000039} O15354 Probable G-protein coupled receptor 37 protein 20030904 {GO:0007186=TAS, GO:0005887=TAS, GO:0004930=IEA, GO:0005789=IEA} G-protein coupled receptor signaling pathway endoplasmic reticulum membrane, integral to plasma membrane G-protein coupled receptor activity Human GPR37L1 IntAct UniProtKB {GO:0005515=PMID:20517885, GO:0008150=GO_REF:0000015, GO:0005886=GO_REF:0000039, GO:0004930=GO_REF:0000037, GO:0016021=PMID:9539149} O60883 Endothelin B receptor-like protein 2 protein 20130415 {GO:0005515=IPI, GO:0008150=ND, GO:0005886=IEA, GO:0004930=IEA, GO:0016021=NAS} biological_process integral to membrane, plasma membrane G-protein coupled receptor activity, protein binding Human UniProtKB:P42785 GPR39 Reactome UniProtKB {GO:0005886=Reactome:REACT_22251, GO:0007186=PMID:9441746, GO:0005887=PMID:9441746, GO:0004930=GO_REF:0000037, GO:0046872=GO_REF:0000037} O43194 G-protein coupled receptor 39 protein 20091019 {GO:0005886=TAS, GO:0007186=TAS, GO:0005887=TAS, GO:0004930=IEA, GO:0046872=IEA} G-protein coupled receptor signaling pathway integral to plasma membrane, plasma membrane G-protein coupled receptor activity, metal ion binding Human GPR45 UniProtKB UniProtKB {GO:0005886=GO_REF:0000039, GO:0004930=GO_REF:0000037, GO:0016021=GO_REF:0000037} Q9Y5Y3 Probable G-protein coupled receptor 45 protein 20130413 {GO:0005886=IEA, GO:0004930=IEA, GO:0016021=IEA} integral to membrane, plasma membrane G-protein coupled receptor activity Human UniProtKB-SubCell:SL-0039 GPR50 PINC UniProtKB {GO:0007186=PMID:8647286, GO:0005887=PMID:8647286, GO:0004930=PMID:8647286, GO:0007267=PMID:8647286, GO:0008502=GO_REF:0000002} Q13585 Melatonin-related receptor protein 20030904 {GO:0007186=TAS, GO:0005887=TAS, GO:0004930=TAS, GO:0007267=TAS, GO:0008502=IEA} G-protein coupled receptor signaling pathway, cell-cell signaling integral to plasma membrane G-protein coupled receptor activity, melatonin receptor activity Human GPR52 PINC UniProtKB {GO:0007186=PMID:9931487, GO:0005887=PMID:9931487, GO:0004930=GO_REF:0000037} Q9Y2T5 Probable G-protein coupled receptor 52 protein 20030904 {GO:0007186=TAS, GO:0005887=TAS, GO:0004930=IEA} G-protein coupled receptor signaling pathway integral to plasma membrane G-protein coupled receptor activity Human GPR56 GDB UniProtKB {GO:0007186=PMID:15004227, GO:0005886=GO_REF:0000038, GO:0007420=PMID:15044805, GO:0005887=PMID:10049584, GO:0007218=GO_REF:0000002, GO:0004930=GO_REF:0000037, GO:0007267=PMID:10049584, GO:0016021=PMID:15004227, GO:0007155=PMID:15674329} Q9Y653 G-protein coupled receptor 56 protein 20050510 {GO:0007186=TAS, GO:0005886=IEA, GO:0007420=IMP, GO:0005887=TAS, GO:0007218=IEA, GO:0004930=IEA, GO:0007267=TAS, GO:0016021=TAS, GO:0007155=IDA} G-protein coupled receptor signaling pathway, brain development, cell adhesion, cell-cell signaling, neuropeptide signaling pathway integral to membrane, integral to plasma membrane, plasma membrane G-protein coupled receptor activity Human GPR61 UniProtKB UniProtKB {GO:0008150=GO_REF:0000015, GO:0005886=GO_REF:0000039, GO:0004930=GO_REF:0000037, GO:0005575=GO_REF:0000015, GO:0016021=GO_REF:0000037} Q9BZJ8 Probable G-protein coupled receptor 61 protein 20061026 {GO:0008150=ND, GO:0005886=IEA, GO:0004930=IEA, GO:0005575=ND, GO:0016021=IEA} biological_process cellular_component, integral to membrane, plasma membrane G-protein coupled receptor activity Human GPR63 UniProtKB UniProtKB {GO:0008150=GO_REF:0000015, GO:0003674=GO_REF:0000015, GO:0016020=GO_REF:0000029, GO:0005886=GO_REF:0000039, GO:0004930=GO_REF:0000037, GO:0016021=GO_REF:0000037} Q9BZJ6 Probable G-protein coupled receptor 63 protein 20061026 {GO:0008150=ND, GO:0003674=ND, GO:0016020=NAS, GO:0005886=IEA, GO:0004930=IEA, GO:0016021=IEA} biological_process integral to membrane, membrane, plasma membrane G-protein coupled receptor activity, molecular_function Human GPR64 HPA UniProtKB {GO:0016324=GO_REF:0000019, GO:0005737=GO_REF:0000052, GO:0007186=PMID:9150425, GO:0005886=GO_REF:0000038, GO:0005887=PMID:9150425, GO:0007218=GO_REF:0000002, GO:0004930=GO_REF:0000037, GO:0007283=PMID:9150425, GO:0016021=PMID:12420295} Q8IZP9 G-protein coupled receptor 64 protein 20100326 {GO:0016324=IEA, GO:0005737=IDA, GO:0007186=TAS, GO:0005886=IEA, GO:0005887=TAS, GO:0007218=IEA, GO:0004930=IEA, GO:0007283=TAS, GO:0016021=TAS} G-protein coupled receptor signaling pathway, neuropeptide signaling pathway, spermatogenesis apical plasma membrane, cytoplasm, integral to membrane, integral to plasma membrane, plasma membrane G-protein coupled receptor activity Human GPR78 UniProtKB UniProtKB {GO:0005886=GO_REF:0000039, GO:0004930=PMID:17363172, GO:0007189=PMID:17363172, GO:0016021=GO_REF:0000037} Q96P69 G-protein coupled receptor 78 protein 20100201 {GO:0005886=IEA, GO:0004930=IDA, GO:0007189=IDA, GO:0016021=IEA} adenylate cyclase-activating G-protein coupled receptor signaling pathway integral to membrane, plasma membrane G-protein coupled receptor activity Human GPR89A GOC UniProtKB {GO:0007165=PMID:12761501, GO:0044070=PMID:18794847, GO:0030660=PMID:18794847, GO:0032580=PMID:18794847, GO:0004871=PMID:12761501, GO:0016021=GO_REF:0000037, GO:0043123=PMID:12761501, GO:0015031=GO_REF:0000037, GO:0008308=PMID:18794847, GO:0051452=PMID:18794847} B7ZAQ6 Golgi pH regulator A protein 20130413 {GO:0007165=IMP, GO:0044070=IDA, GO:0030660=IDA, GO:0032580=IDA, GO:0004871=IMP, GO:0016021=IEA, GO:0043123=IMP, GO:0015031=IEA, GO:0008308=IDA, GO:0051452=IDA} intracellular pH reduction, positive regulation of I-kappaB kinase/NF-kappaB cascade, protein transport, regulation of anion transport, signal transduction Golgi cisterna membrane, Golgi-associated vesicle membrane, integral to membrane signal transducer activity, voltage-gated anion channel activity Human GPR89B UniProtKB UniProtKB {GO:0005244=GO_REF:0000037, GO:0000139=GO_REF:0000039, GO:0016021=GO_REF:0000037, GO:0015031=GO_REF:0000037} P0CG08 Golgi pH regulator B protein 20130413 {GO:0005244=IEA, GO:0000139=IEA, GO:0016021=IEA, GO:0015031=IEA} protein transport Golgi membrane, integral to membrane voltage-gated ion channel activity Human UniProtKB-SubCell:SL-0134 GPR89C UniProtKB UniProtKB {GO:0016021=GO_REF:0000037} A6NKF9 Putative Golgi pH regulator C protein 20130413 {GO:0016021=IEA} integral to membrane Human UniProtKB-KW:KW-0812 GPRASP1 IntAct UniProtKB {GO:0005515=PMID:15086532, GO:0005737=GO_REF:0000039} Q5JY77 G-protein coupled receptor-associated sorting protein 1 protein 20130415 {GO:0005515=IPI, GO:0005737=IEA} cytoplasm protein binding Human UniProtKB:P41143 GPRASP2 LIFEdb UniProtKB {GO:0005737=GO_REF:0000054, GO:0001540=GO_REF:0000019} Q96D09 G-protein coupled receptor-associated sorting protein 2 protein 20100607 {GO:0005737=IDA, GO:0001540=IEA} cytoplasm beta-amyloid binding Human GPRC5A HPA UniProtKB {GO:0007165=PMID:9857033, GO:0005794=GO_REF:0000052, GO:0005886=GO_REF:0000052, GO:0005887=PMID:9857033, GO:0004930=GO_REF:0000037, GO:0016021=GO_REF:0000002, GO:0030659=GO_REF:0000039, GO:0043231=GO_REF:0000052} Q8NFJ5 Retinoic acid-induced protein 3 protein 20120912 {GO:0007165=TAS, GO:0005794=IDA, GO:0005886=IDA, GO:0005887=TAS, GO:0004930=IEA, GO:0016021=IEA, GO:0030659=IEA, GO:0043231=IDA} signal transduction Golgi apparatus, cytoplasmic vesicle membrane, integral to membrane, integral to plasma membrane, intracellular membrane-bounded organelle, plasma membrane G-protein coupled receptor activity Human GPRC5B HPA UniProtKB {GO:0005794=GO_REF:0000052, GO:0005886=GO_REF:0000039, GO:0004930=GO_REF:0000037, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0016021=GO_REF:0000037, GO:0030659=GO_REF:0000039, GO:0070062=PMID:21557262, GO:0043231=GO_REF:0000052} Q9NZH0 G-protein coupled receptor family C group 5 member B protein 20101115 {GO:0005794=IDA, GO:0005886=IEA, GO:0004930=IEA, GO:0005730=IDA, GO:0005634=IDA, GO:0016021=IEA, GO:0030659=IEA, GO:0070062=IDA, GO:0043231=IDA} Golgi apparatus, cytoplasmic vesicle membrane, extracellular vesicular exosome, integral to membrane, intracellular membrane-bounded organelle, nucleolus, nucleus, plasma membrane G-protein coupled receptor activity Human GPRC5C PINC UniProtKB {GO:0005739=GO_REF:0000019, GO:0007186=PMID:10783259, GO:0005887=PMID:10783259, GO:0004930=GO_REF:0000037, GO:0016021=GO_REF:0000002, GO:0030659=GO_REF:0000039} Q9NQ84 G-protein coupled receptor family C group 5 member C protein 20050308 {GO:0005739=IEA, GO:0007186=TAS, GO:0005887=TAS, GO:0004930=IEA, GO:0016021=IEA, GO:0030659=IEA} G-protein coupled receptor signaling pathway cytoplasmic vesicle membrane, integral to membrane, integral to plasma membrane, mitochondrion G-protein coupled receptor activity Human GPRIN1 UniProtKB UniProtKB {GO:0051219=GO_REF:0000019, GO:0005886=GO_REF:0000039, GO:0031175=GO_REF:0000019, GO:0030426=GO_REF:0000039} Q7Z2K8 G protein-regulated inducer of neurite outgrowth 1 protein 20130413 {GO:0051219=IEA, GO:0005886=IEA, GO:0031175=IEA, GO:0030426=IEA} neuron projection development growth cone, plasma membrane phosphoprotein binding Human UniProtKB-SubCell:SL-0288 GPRIN2 null null {} null null null null {} null null null GPS1 PINC UniProtKB {GO:0000188=PMID:8943324, GO:0007049=PMID:8943324, GO:0005737=GO_REF:0000039, GO:0008180=PMID:18850735, GO:0010388=PMID:19141280, GO:0007254=PMID:8943324, GO:0005095=PMID:8943324} Q13098 COP9 signalosome complex subunit 1 protein 20030904 {GO:0000188=TAS, GO:0007049=TAS, GO:0005737=IEA, GO:0008180=IDA, GO:0010388=IDA, GO:0007254=TAS, GO:0005095=TAS} JNK cascade, cell cycle, cullin deneddylation, inactivation of MAPK activity cytoplasm, signalosome GTPase inhibitor activity Human GPS2 IntAct UniProtKB {GO:0000188=PMID:8943324, GO:0005515=PMID:22190034, GO:0007049=PMID:8943324, GO:0046329=PMID:11931768, GO:0017053=PMID:12628926, GO:0003714=PMID:11931768, GO:0007254=PMID:8943324, GO:0000122=PMID:11931768, GO:0005095=PMID:8943324} Q13227 G protein pathway suppressor 2 protein 20130415 {GO:0000188=TAS, GO:0005515=IPI, GO:0007049=TAS, GO:0046329=IDA, GO:0017053=IDA, GO:0003714=IDA, GO:0007254=TAS, GO:0000122=IDA, GO:0005095=TAS} JNK cascade, cell cycle, inactivation of MAPK activity, negative regulation of JNK cascade, negative regulation of transcription from RNA polymerase II promoter transcriptional repressor complex GTPase inhibitor activity, protein binding, transcription corepressor activity Human UniProtKB:P12504 GPSM1 HPA UniProtKB {GO:0005794=GO_REF:0000052, GO:0008277=GO_REF:0000002, GO:0005886=GO_REF:0000039, GO:0000139=GO_REF:0000039, GO:0005730=GO_REF:0000052, GO:0005789=GO_REF:0000039, GO:0005634=GO_REF:0000052, GO:0005092=GO_REF:0000002, GO:0030154=GO_REF:0000037, GO:0005829=GO_REF:0000039, GO:0007399=GO_REF:0000037} Q86YR5 G-protein-signaling modulator 1 protein 20110516 {GO:0005794=IDA, GO:0008277=IEA, GO:0005886=IEA, GO:0000139=IEA, GO:0005730=IDA, GO:0005789=IEA, GO:0005634=IDA, GO:0005092=IEA, GO:0030154=IEA, GO:0005829=IEA, GO:0007399=IEA} cell differentiation, nervous system development, regulation of G-protein coupled receptor protein signaling pathway Golgi apparatus, Golgi membrane, cytosol, endoplasmic reticulum membrane, nucleolus, nucleus, plasma membrane GDP-dissociation inhibitor activity Human GPSM2 ENSEMBL UniProtKB {GO:0005515=PMID:15537540, GO:0005737=GO_REF:0000052, GO:0008277=GO_REF:0000002, GO:0007186=PMID:8973305, GO:0005730=GO_REF:0000052, GO:0060487=GO_REF:0000019, GO:0000132=GO_REF:0000019, GO:0045177=GO_REF:0000019, GO:0005634=GO_REF:0000052, GO:0005092=GO_REF:0000002, GO:0005938=GO_REF:0000039, GO:0042802=PMID:15537540} Q5T1N9 G-protein-signaling modulator 2 protein 20130413 {GO:0005515=IPI, GO:0005737=IDA, GO:0008277=IEA, GO:0007186=TAS, GO:0005730=IDA, GO:0060487=IEA, GO:0000132=IEA, GO:0045177=IEA, GO:0005634=IDA, GO:0005092=IEA, GO:0005938=IEA, GO:0042802=IPI} G-protein coupled receptor signaling pathway, establishment of mitotic spindle orientation, lung epithelial cell differentiation, regulation of G-protein coupled receptor protein signaling pathway apical part of cell, cell cortex, cytoplasm, nucleolus, nucleus GDP-dissociation inhibitor activity, identical protein binding, protein binding Human Ensembl:ENSMUSP00000029482 GPSM3 UniProtKB UniProtKB {GO:0003674=GO_REF:0000015, GO:0008150=GO_REF:0000015, GO:0005737=GO_REF:0000039, GO:0008277=GO_REF:0000002, GO:0005575=GO_REF:0000015, GO:0005092=GO_REF:0000002, GO:0030695=GO_REF:0000002} Q9Y4H4 G-protein-signaling modulator 3 protein 20061026 {GO:0003674=ND, GO:0008150=ND, GO:0005737=IEA, GO:0008277=IEA, GO:0005575=ND, GO:0005092=IEA, GO:0030695=IEA} biological_process, regulation of G-protein coupled receptor protein signaling pathway cellular_component, cytoplasm GDP-dissociation inhibitor activity, GTPase regulator activity, molecular_function Human GPT Reactome UniProtKB {GO:0034641=Reactome:REACT_13, GO:0006807=GO_REF:0000029, GO:0005737=GO_REF:0000029, GO:0004021=Reactome:REACT_356, GO:0042853=GO_REF:0000041, GO:0030170=GO_REF:0000002, GO:0006094=GO_REF:0000029, GO:0008652=Reactome:REACT_238, GO:0044281=Reactome:REACT_111217, GO:0005829=Reactome:REACT_356} P24298 Alanine aminotransferase 1 protein 20100210 {GO:0034641=TAS, GO:0006807=NAS, GO:0005737=NAS, GO:0004021=EXP, GO:0042853=IEA, GO:0030170=IEA, GO:0006094=NAS, GO:0008652=TAS, GO:0044281=TAS, GO:0005829=TAS} L-alanine catabolic process, cellular amino acid biosynthetic process, cellular nitrogen compound metabolic process, gluconeogenesis, nitrogen compound metabolic process, small molecule metabolic process cytoplasm, cytosol L-alanine:2-oxoglutarate aminotransferase activity, pyridoxal phosphate binding Human GPT2 Reactome UniProtKB {GO:0034641=Reactome:REACT_13, GO:0004021=Reactome:REACT_21311, GO:0009058=GO_REF:0000002, GO:0042851=PMID:11863375, GO:0005759=Reactome:REACT_21311, GO:0006103=PMID:11863375, GO:0042853=GO_REF:0000041, GO:0030170=GO_REF:0000002, GO:0008652=Reactome:REACT_238, GO:0044281=Reactome:REACT_111217, GO:0003824=GO_REF:0000002} Q8TD30 Alanine aminotransferase 2 protein 20130213 {GO:0034641=TAS, GO:0004021=EXP, GO:0009058=IEA, GO:0042851=IDA, GO:0005759=TAS, GO:0006103=IDA, GO:0042853=IEA, GO:0030170=IEA, GO:0008652=TAS, GO:0044281=TAS, GO:0003824=IEA} 2-oxoglutarate metabolic process, L-alanine catabolic process, L-alanine metabolic process, biosynthetic process, cellular amino acid biosynthetic process, cellular nitrogen compound metabolic process, small molecule metabolic process mitochondrial matrix L-alanine:2-oxoglutarate aminotransferase activity, catalytic activity, pyridoxal phosphate binding Human GPX1 BHF-UCL UniProtKB {GO:0019369=Reactome:REACT_147851, GO:0042542=PMID:12829378, GO:0009650=PMID:17097614, GO:0060047=PMID:14573732, GO:0001659=GO_REF:0000019, GO:0007605=GO_REF:0000019, GO:0006749=PMID:12829378, GO:0004602=PMID:12829378, GO:0043523=GO_REF:0000019, GO:0006195=Reactome:REACT_2086, GO:0045444=GO_REF:0000019, GO:0009410=GO_REF:0000019, GO:0042744=PMID:15203190, GO:0006979=GO_REF:0000002, GO:0010332=GO_REF:0000019, GO:0033194=GO_REF:0000019, GO:0014902=GO_REF:0000019, GO:0051702=GO_REF:0000019, GO:0048741=GO_REF:0000019, GO:0009636=GO_REF:0000019, GO:0033599=PMID:16945136, GO:0043534=GO_REF:0000019, GO:0001885=GO_REF:0000019, GO:0006144=Reactome:REACT_522, GO:0006641=GO_REF:0000019, GO:0045454=PMID:12829378, GO:0051450=GO_REF:0000019, GO:0051897=GO_REF:0000019, GO:0017124=PMID:12893824, GO:0002862=GO_REF:0000019, GO:0004866=PMID:12751788, GO:0001836=PMID:12221075, GO:0044281=Reactome:REACT_111217, GO:0005829=Reactome:REACT_150391, GO:0005739=PMID:10833429, GO:0005737=PMID:10833429, GO:0042311=GO_REF:0000019, GO:0018158=GO_REF:0000019, GO:0043403=GO_REF:0000019, GO:0043154=PMID:12221075, GO:0043066=PMID:12221075, GO:0019372=Reactome:REACT_150209, GO:0008631=GO_REF:0000019, GO:0060055=GO_REF:0000019, GO:0010269=PMID:12810669, GO:0055086=Reactome:REACT_1698, GO:0006917=GO_REF:0000019, GO:0061136=PMID:12751788, GO:0009609=GO_REF:0000019, GO:0040029=PMID:16132718} P07203 Glutathione peroxidase 1 protein 20071109 {GO:0019369=TAS, GO:0042542=IMP, GO:0009650=IMP, GO:0060047=IMP, GO:0001659=IEA, GO:0007605=IEA, GO:0006749=IDA, GO:0004602=IDA, GO:0043523=IEA, GO:0006195=TAS, GO:0045444=IEA, GO:0009410=IEA, GO:0042744=IDA, GO:0006979=IEA, GO:0010332=IEA, GO:0033194=IEA, GO:0014902=IEA, GO:0051702=IEA, GO:0048741=IEA, GO:0009636=IEA, GO:0033599=IMP, GO:0043534=IEA, GO:0001885=IEA, GO:0006144=TAS, GO:0006641=IEA, GO:0045454=IDA, GO:0051450=IEA, GO:0051897=IEA, GO:0017124=IPI, GO:0002862=IEA, GO:0004866=IDA, GO:0001836=IMP, GO:0044281=TAS, GO:0005829=TAS, GO:0005739=IDA, GO:0005737=IDA, GO:0042311=IEA, GO:0018158=IEA, GO:0043403=IEA, GO:0043154=IMP, GO:0043066=IMP, GO:0019372=TAS, GO:0008631=IEA, GO:0060055=IEA, GO:0010269=IMP, GO:0055086=TAS, GO:0006917=IEA, GO:0061136=IDA, GO:0009609=IEA, GO:0040029=IDA} UV protection, angiogenesis involved in wound healing, arachidonic acid metabolic process, blood vessel endothelial cell migration, cell redox homeostasis, endothelial cell development, fat cell differentiation, glutathione metabolic process, heart contraction, hydrogen peroxide catabolic process, induction of apoptosis, interaction with symbiont, intrinsic apoptotic signaling pathway in response to oxidative stress, lipoxygenase pathway, myoblast proliferation, myotube differentiation, negative regulation of apoptotic process, negative regulation of cysteine-type endopeptidase activity involved in apoptotic process, negative regulation of inflammatory response to antigenic stimulus, nucleobase-containing small molecule metabolic process, positive regulation of protein kinase B signaling cascade, protein oxidation, purine nucleobase metabolic process, purine nucleotide catabolic process, regulation of gene expression, epigenetic, regulation of mammary gland epithelial cell proliferation, regulation of neuron apoptotic process, regulation of proteasomal protein catabolic process, release of cytochrome c from mitochondria, response to gamma radiation, response to hydrogen peroxide, response to hydroperoxide, response to oxidative stress, response to selenium ion, response to symbiotic bacterium, response to toxic substance, response to xenobiotic stimulus, sensory perception of sound, skeletal muscle fiber development, skeletal muscle tissue regeneration, small molecule metabolic process, temperature homeostasis, triglyceride metabolic process, vasodilation cytoplasm, cytosol, mitochondrion SH3 domain binding, endopeptidase inhibitor activity, glutathione peroxidase activity Human GPX2 HPA UniProtKB {GO:0004602=GO_REF:0000003, GO:0005737=GO_REF:0000052, GO:0001659=GO_REF:0000019, GO:0002862=GO_REF:0000019, GO:0051702=GO_REF:0000019, GO:0009609=GO_REF:0000019, GO:0005730=GO_REF:0000052, GO:0009055=PMID:8428933, GO:0005634=GO_REF:0000052, GO:0006979=GO_REF:0000002} P18283 Glutathione peroxidase 2 protein 20101115 {GO:0004602=IEA, GO:0005737=IDA, GO:0001659=IEA, GO:0002862=IEA, GO:0051702=IEA, GO:0009609=IEA, GO:0005730=IDA, GO:0009055=TAS, GO:0005634=IDA, GO:0006979=IEA} interaction with symbiont, negative regulation of inflammatory response to antigenic stimulus, response to oxidative stress, response to symbiotic bacterium, temperature homeostasis cytoplasm, nucleolus, nucleus electron carrier activity, glutathione peroxidase activity Human GPX4 Reactome UniProtKB {GO:0019369=Reactome:REACT_147851, GO:0005739=PMID:9705830, GO:0004602=PMID:9705830, GO:0019372=Reactome:REACT_150209, GO:0047066=GO_REF:0000003, GO:0007275=GO_REF:0000037, GO:0044281=Reactome:REACT_111217, GO:0006644=PMID:8039723, GO:0006979=GO_REF:0000002, GO:0005829=Reactome:REACT_150391, GO:0055114=PMID:9705830} P36969 Phospholipid hydroperoxide glutathione peroxidase, mitochondrial protein 20130301 {GO:0019369=TAS, GO:0005739=TAS, GO:0004602=TAS, GO:0019372=TAS, GO:0047066=IEA, GO:0007275=IEA, GO:0044281=TAS, GO:0006644=TAS, GO:0006979=IEA, GO:0005829=TAS, GO:0055114=TAS} arachidonic acid metabolic process, lipoxygenase pathway, multicellular organismal development, oxidation-reduction process, phospholipid metabolic process, response to oxidative stress, small molecule metabolic process cytosol, mitochondrion glutathione peroxidase activity, phospholipid-hydroperoxide glutathione peroxidase activity Human GPX7 UniProtKB UniProtKB {GO:0004602=GO_REF:0000003, GO:0005576=GO_REF:0000039, GO:0006979=GO_REF:0000002} Q96SL4 Glutathione peroxidase 7 protein 20130413 {GO:0004602=IEA, GO:0005576=IEA, GO:0006979=IEA} response to oxidative stress extracellular region glutathione peroxidase activity Human UniProtKB-SubCell:SL-0243 GPX8 UniProtKB UniProtKB {GO:0004602=GO_REF:0000003, GO:0016021=GO_REF:0000037, GO:0006979=GO_REF:0000002} Q8TED1 Probable glutathione peroxidase 8 protein 20130413 {GO:0004602=IEA, GO:0016021=IEA, GO:0006979=IEA} response to oxidative stress integral to membrane glutathione peroxidase activity Human EC:1.11.1.9 GRAMD1A UniProtKB UniProtKB {GO:0016021=GO_REF:0000037} Q96CP6 GRAM domain-containing protein 1A protein 20130413 {GO:0016021=IEA} integral to membrane Human UniProtKB-KW:KW-0812 GRAMD1C UniProtKB UniProtKB {GO:0016021=GO_REF:0000037} Q8IYS0 GRAM domain-containing protein 1C protein 20130413 {GO:0016021=IEA} integral to membrane Human UniProtKB-KW:KW-0812 GRAMD3 UniProtKB UniProtKB {GO:0005881=PMID:23264731} Q96HH9 GRAM domain-containing protein 3 protein 20130311 {GO:0005881=IDA} cytoplasmic microtubule Human GRAMD4 UniProtKB UniProtKB {GO:0031966=GO_REF:0000039, GO:0006915=GO_REF:0000037, GO:0016021=GO_REF:0000037} Q6IC98 GRAM domain-containing protein 4 protein 20130413 {GO:0031966=IEA, GO:0006915=IEA, GO:0016021=IEA} apoptotic process integral to membrane, mitochondrial membrane Human UniProtKB-SubCell:SL-0171 GRAP Reactome UniProtKB {GO:0005737=PMID:8647802, GO:0005070=PMID:8647802, GO:0007267=PMID:8647802, GO:0007265=PMID:8647802, GO:0005829=Reactome:REACT_111192} Q13588 GRB2-related adapter protein protein 20110711 {GO:0005737=TAS, GO:0005070=TAS, GO:0007267=TAS, GO:0007265=TAS, GO:0005829=TAS} Ras protein signal transduction, cell-cell signaling cytoplasm, cytosol SH3/SH2 adaptor activity Human GRAP2 HPA UniProtKB {GO:0005515=PMID:12359715, GO:0050852=Reactome:REACT_12526, GO:0005737=GO_REF:0000052, GO:0045087=Reactome:REACT_6802, GO:0005070=PMID:9878555, GO:0031295=Reactome:REACT_19344, GO:0007267=PMID:9878555, GO:0005730=GO_REF:0000052, GO:0007265=PMID:9878555, GO:0005634=GO_REF:0000052, GO:0005829=Reactome:REACT_147838, GO:0005768=PMID:21179510} O75791 GRB2-related adapter protein 2 protein 20080205 {GO:0005515=IPI, GO:0050852=TAS, GO:0005737=IDA, GO:0045087=TAS, GO:0005070=TAS, GO:0031295=TAS, GO:0007267=TAS, GO:0005730=IDA, GO:0007265=TAS, GO:0005634=IDA, GO:0005829=TAS, GO:0005768=IDA} Ras protein signal transduction, T cell costimulation, T cell receptor signaling pathway, cell-cell signaling, innate immune response cytoplasm, cytosol, endosome, nucleolus, nucleus SH3/SH2 adaptor activity, protein binding Human GRASP UniProtKB UniProtKB {GO:0007165=GO_REF:0000019, GO:0048471=GO_REF:0000039, GO:0030054=GO_REF:0000037, GO:0008104=GO_REF:0000019, GO:0030306=GO_REF:0000019, GO:0005886=GO_REF:0000039, GO:0045211=GO_REF:0000039, GO:0030165=GO_REF:0000019} Q7Z6J2 General receptor for phosphoinositides 1-associated scaffold protein protein 20130413 {GO:0007165=IEA, GO:0048471=IEA, GO:0030054=IEA, GO:0008104=IEA, GO:0030306=IEA, GO:0005886=IEA, GO:0045211=IEA, GO:0030165=IEA} protein localization, signal transduction cell junction, perinuclear region of cytoplasm, plasma membrane, postsynaptic membrane ADP-ribosylation factor binding, PDZ domain binding Human UniProtKB-SubCell:SL-0198 GRB10 BHF-UCL UniProtKB {GO:0008286=Reactome:REACT_498, GO:0005515=PMID:8798570, GO:0030949=PMID:15060076, GO:0005886=PMID:9006901, GO:0005158=PMID:15664450, GO:0046627=PMID:15664450, GO:0030178=PMID:17376403, GO:0045719=GO_REF:0000019, GO:0005829=Reactome:REACT_111192, GO:0042326=GO_REF:0000019, GO:0007165=GO_REF:0000002, GO:0005737=PMID:9006901, GO:0005543=GO_REF:0000002, GO:0005070=GO_REF:0000019, GO:0046325=PMID:15664450, GO:0048009=GO_REF:0000019, GO:0042327=GO_REF:0000019} Q13322 Growth factor receptor-bound protein 10 protein 20090430 {GO:0008286=TAS, GO:0005515=IPI, GO:0030949=IDA, GO:0005886=TAS, GO:0005158=ISS, GO:0046627=ISS, GO:0030178=IDA, GO:0045719=IEA, GO:0005829=TAS, GO:0042326=IEA, GO:0007165=IEA, GO:0005737=TAS, GO:0005543=IEA, GO:0005070=IEA, GO:0046325=ISS, GO:0048009=IEA, GO:0042327=IEA} insulin receptor signaling pathway, insulin-like growth factor receptor signaling pathway, negative regulation of Wnt receptor signaling pathway, negative regulation of glucose import, negative regulation of glycogen biosynthetic process, negative regulation of insulin receptor signaling pathway, negative regulation of phosphorylation, positive regulation of phosphorylation, positive regulation of vascular endothelial growth factor receptor signaling pathway, signal transduction cytoplasm, cytosol, plasma membrane SH3/SH2 adaptor activity, insulin receptor binding, phospholipid binding, protein binding Human UniProtKB:Q60760 GRB14 BHF-UCL UniProtKB {GO:0007165=GO_REF:0000002, GO:0005737=PMID:11278563, GO:0005543=GO_REF:0000002, GO:0005886=PMID:11278563, GO:0000139=GO_REF:0000039, GO:0007596=Reactome:REACT_604, GO:0005070=GO_REF:0000019, GO:0050900=Reactome:REACT_12051, GO:0010008=GO_REF:0000039, GO:0043231=PMID:11278563, GO:0005829=Reactome:REACT_16885} Q14449 Growth factor receptor-bound protein 14 protein 20081217 {GO:0007165=IEA, GO:0005737=IDA, GO:0005543=IEA, GO:0005886=IDA, GO:0000139=IEA, GO:0007596=TAS, GO:0005070=IEA, GO:0050900=TAS, GO:0010008=IEA, GO:0043231=IDA, GO:0005829=TAS} blood coagulation, leukocyte migration, signal transduction Golgi membrane, cytoplasm, cytosol, endosome membrane, intracellular membrane-bounded organelle, plasma membrane SH3/SH2 adaptor activity, phospholipid binding Human GRB2 BHF-UCL UniProtKB {GO:0008286=Reactome:REACT_498, GO:0005515=PMID:22726438, GO:0017124=PMID:19509291, GO:0005154=PMID:12577067, GO:0005886=Reactome:REACT_147854, GO:0031295=Reactome:REACT_19344, GO:0060670=GO_REF:0000019, GO:0007267=PMID:8253073, GO:0005634=PMID:21179510, GO:0043560=PMID:8388384, GO:0007265=Reactome:REACT_12033, GO:0050900=Reactome:REACT_12051, GO:0051291=GO_REF:0000019, GO:0030154=GO_REF:0000019, GO:0005829=Reactome:REACT_12490, GO:0031623=PMID:14985334, GO:0005737=PMID:21179510, GO:0048646=GO_REF:0000019, GO:0030838=GO_REF:0000019, GO:0008180=PMID:22561606, GO:0007173=Reactome:REACT_9417, GO:0007411=Reactome:REACT_18266, GO:0043408=GO_REF:0000019, GO:0012506=GO_REF:0000019, GO:0070436=PMID:20086093, GO:0048011=Reactome:REACT_11061, GO:0005794=GO_REF:0000039, GO:0019901=PMID:20086093, GO:0005168=PMID:15488758, GO:0048015=Reactome:REACT_12464, GO:0019903=GO_REF:0000019, GO:0019904=GO_REF:0000019, GO:0007568=GO_REF:0000019, GO:0042059=Reactome:REACT_12484, GO:0030168=Reactome:REACT_798, GO:0071479=PMID:20160708, GO:0042770=PMID:20160708, GO:0046875=PMID:12925710, GO:0008543=Reactome:REACT_9470, GO:0007596=Reactome:REACT_604, GO:0045087=Reactome:REACT_6802, GO:0005070=PMID:8253073, GO:0019048=GO_REF:0000037, GO:0001784=GO_REF:0000019, GO:2000379=PMID:20160708, GO:0038096=Reactome:REACT_160123, GO:0005768=PMID:21179510} P62993 Growth factor receptor-bound protein 2 protein 20120308 {GO:0008286=TAS, GO:0005515=IPI, GO:0017124=IDA, GO:0005154=IPI, GO:0005886=TAS, GO:0031295=TAS, GO:0060670=IEA, GO:0007267=TAS, GO:0005634=IDA, GO:0043560=IPI, GO:0007265=TAS, GO:0050900=TAS, GO:0051291=IEA, GO:0030154=IEA, GO:0005829=TAS, GO:0031623=IMP, GO:0005737=IDA, GO:0048646=IEA, GO:0030838=IEA, GO:0008180=IDA, GO:0007173=TAS, GO:0007411=TAS, GO:0043408=IEA, GO:0012506=IEA, GO:0070436=IDA, GO:0048011=TAS, GO:0005794=IEA, GO:0019901=IPI, GO:0005168=IPI, GO:0048015=TAS, GO:0019903=IEA, GO:0019904=IEA, GO:0007568=IEA, GO:0042059=TAS, GO:0030168=TAS, GO:0071479=IMP, GO:0042770=IMP, GO:0046875=IPI, GO:0008543=TAS, GO:0007596=TAS, GO:0045087=TAS, GO:0005070=TAS, GO:0019048=IEA, GO:0001784=IEA, GO:2000379=IMP, GO:0038096=TAS, GO:0005768=IDA} Fc-gamma receptor signaling pathway involved in phagocytosis, Ras protein signal transduction, T cell costimulation, aging, anatomical structure formation involved in morphogenesis, axon guidance, blood coagulation, branching involved in labyrinthine layer morphogenesis, cell differentiation, cell-cell signaling, cellular response to ionizing radiation, epidermal growth factor receptor signaling pathway, fibroblast growth factor receptor signaling pathway, innate immune response, insulin receptor signaling pathway, leukocyte migration, negative regulation of epidermal growth factor receptor signaling pathway, neurotrophin TRK receptor signaling pathway, phosphatidylinositol-mediated signaling, platelet activation, positive regulation of actin filament polymerization, positive regulation of reactive oxygen species metabolic process, protein heterooligomerization, receptor internalization, regulation of MAPK cascade, signal transduction in response to DNA damage, virus-host interaction Golgi apparatus, Grb2-EGFR complex, cytoplasm, cytosol, endosome, nucleus, plasma membrane, signalosome, vesicle membrane SH3 domain binding, SH3/SH2 adaptor activity, ephrin receptor binding, epidermal growth factor receptor binding, insulin receptor substrate binding, neurotrophin TRKA receptor binding, phosphotyrosine binding, protein binding, protein domain specific binding, protein kinase binding, protein phosphatase binding Human GRB7 IntAct UniProtKB {GO:0005515=PMID:20665473, GO:0017148=GO_REF:0000024, GO:0030335=PMID:12021278, GO:0005886=GO_REF:0000039, GO:0019901=PMID:12021278, GO:0010494=GO_REF:0000024, GO:0003723=GO_REF:0000037, GO:0042995=GO_REF:0000039, GO:0050900=Reactome:REACT_12051, GO:0042802=PMID:15841400, GO:0005829=Reactome:REACT_115703, GO:0034063=GO_REF:0000024, GO:0007173=PMID:9710451, GO:0007596=Reactome:REACT_604, GO:0005070=PMID:9710451, GO:0035091=PMID:12021278, GO:0005925=PMID:12021278} Q14451 Growth factor receptor-bound protein 7 protein 20130415 {GO:0005515=IPI, GO:0017148=ISS, GO:0030335=IDA, GO:0005886=IEA, GO:0019901=IDA, GO:0010494=ISS, GO:0003723=IEA, GO:0042995=IEA, GO:0050900=TAS, GO:0042802=IPI, GO:0005829=TAS, GO:0034063=ISS, GO:0007173=TAS, GO:0007596=TAS, GO:0005070=TAS, GO:0035091=IDA, GO:0005925=IDA} blood coagulation, epidermal growth factor receptor signaling pathway, leukocyte migration, negative regulation of translation, positive regulation of cell migration, stress granule assembly cell projection, cytoplasmic stress granule, cytosol, focal adhesion, plasma membrane RNA binding, SH3/SH2 adaptor activity, identical protein binding, phosphatidylinositol binding, protein binding, protein kinase binding Human UniProtKB:Q14451 GREM1 BHF-UCL UniProtKB {GO:0005515=PMID:16545136, GO:0042346=GO_REF:0000019, GO:0008284=PMID:16545136, GO:0030308=GO_REF:0000019, GO:0001658=GO_REF:0000019, GO:0033689=PMID:15539560, GO:0002042=PMID:9660951, GO:0007267=GO_REF:0000019, GO:0010717=PMID:16816361, GO:0009954=GO_REF:0000019, GO:0030326=GO_REF:0000019, GO:0032872=PMID:9660951, GO:0060394=PMID:15539560, GO:0051893=GO_REF:0000019, GO:0060676=GO_REF:0000019, GO:0005615=PMID:9660951, GO:0051973=PMID:16545136, GO:0030514=PMID:15539560, GO:0016015=PMID:9660951, GO:0030296=GO_REF:0000019, GO:0051092=GO_REF:0000019, GO:0036122=PMID:9660951, GO:0045944=PMID:9660951, GO:0030199=PMID:15539560, GO:0090191=GO_REF:0000019, GO:0090090=PMID:15539560, GO:0048018=PMID:9660951, GO:0090190=GO_REF:0000019, GO:0009986=GO_REF:0000019, GO:0006915=GO_REF:0000019, GO:0090291=PMID:15539560, GO:0030502=PMID:15539560, GO:0005125=GO_REF:0000037, GO:0045766=GO_REF:0000019, GO:2000727=PMID:9660951, GO:0000902=PMID:16545136, GO:0046851=PMID:15539560, GO:0003337=GO_REF:0000019, GO:0072331=PMID:9660951, GO:1900155=PMID:15539560, GO:0048263=PMID:9660951, GO:0043184=PMID:9660951, GO:1900158=PMID:15539560, GO:0090027=GO_REF:0000024, GO:0045892=GO_REF:0000019, GO:0003257=PMID:9660951} O60565 Gremlin-1 protein 20120319 {GO:0005515=IPI, GO:0042346=IEA, GO:0008284=IDA, GO:0030308=IEA, GO:0001658=IEA, GO:0033689=IMP, GO:0002042=ISS, GO:0007267=IEA, GO:0010717=IMP, GO:0009954=IEA, GO:0030326=IEA, GO:0032872=ISS, GO:0060394=IDA, GO:0051893=IEA, GO:0060676=IEA, GO:0005615=NAS, GO:0051973=IDA, GO:0030514=IDA, GO:0016015=ISS, GO:0030296=IEA, GO:0051092=IEA, GO:0036122=ISS, GO:0045944=ISS, GO:0030199=IMP, GO:0090191=IEA, GO:0090090=IDA, GO:0048018=ISS, GO:0090190=IEA, GO:0009986=IEA, GO:0006915=IEA, GO:0090291=IMP, GO:0030502=IMP, GO:0005125=IEA, GO:0045766=IEA, GO:2000727=ISS, GO:0000902=IDA, GO:0046851=IMP, GO:0003337=IEA, GO:0072331=ISS, GO:1900155=IMP, GO:0048263=IMP, GO:0043184=ISS, GO:1900158=IMP, GO:0090027=ISS, GO:0045892=IEA, GO:0003257=ISS} apoptotic process, branching involved in ureteric bud morphogenesis, cell migration involved in sprouting angiogenesis, cell morphogenesis, cell-cell signaling, collagen fibril organization, determination of dorsal identity, embryonic limb morphogenesis, mesenchymal to epithelial transition involved in metanephros morphogenesis, negative regulation of BMP signaling pathway, negative regulation of bone mineralization, negative regulation of bone mineralization involved in bone maturation, negative regulation of bone remodeling, negative regulation of bone trabecula formation, negative regulation of branching involved in ureteric bud morphogenesis, negative regulation of canonical Wnt receptor signaling pathway, negative regulation of cell growth, negative regulation of monocyte chemotaxis, negative regulation of osteoblast proliferation, negative regulation of osteoclast proliferation, negative regulation of pathway-restricted SMAD protein phosphorylation, negative regulation of transcription, DNA-dependent, positive regulation of NF-kappaB import into nucleus, positive regulation of NF-kappaB transcription factor activity, positive regulation of angiogenesis, positive regulation of branching involved in ureteric bud morphogenesis, positive regulation of cardiac muscle cell differentiation, positive regulation of cell proliferation, positive regulation of telomerase activity, positive regulation of transcription from RNA polymerase II promoter, positive regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation, proximal/distal pattern formation, regulation of epithelial to mesenchymal transition, regulation of focal adhesion assembly, regulation of stress-activated MAPK cascade, signal transduction by p53 class mediator, ureteric bud formation cell surface, extracellular space BMP binding, cytokine activity, morphogen activity, protein binding, protein tyrosine kinase activator activity, receptor agonist activity, vascular endothelial growth factor receptor 2 binding Human UniProtKB:O70326 GREM2 Reactome UniProtKB {GO:0005576=Reactome:REACT_12026, GO:0030509=Reactome:REACT_12034, GO:0005615=GO_REF:0000037, GO:0005125=GO_REF:0000037} Q9H772 Gremlin-2 protein 20130301 {GO:0005576=TAS, GO:0030509=TAS, GO:0005615=IEA, GO:0005125=IEA} BMP signaling pathway extracellular region, extracellular space cytokine activity Human GRHL1 HPA UniProtKB {GO:0005737=GO_REF:0000052, GO:0006355=GO_REF:0000037, GO:0005794=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0005654=Reactome:REACT_115770, GO:0007275=GO_REF:0000037, GO:0044281=Reactome:REACT_111217, GO:0003677=GO_REF:0000037, GO:0044255=Reactome:REACT_22279, GO:0006351=GO_REF:0000037} Q9NZI5 Grainyhead-like protein 1 homolog protein 20080205 {GO:0005737=IDA, GO:0006355=IEA, GO:0005794=IDA, GO:0005634=IDA, GO:0005654=TAS, GO:0007275=IEA, GO:0044281=TAS, GO:0003677=IEA, GO:0044255=TAS, GO:0006351=IEA} cellular lipid metabolic process, multicellular organismal development, regulation of transcription, DNA-dependent, small molecule metabolic process, transcription, DNA-dependent Golgi apparatus, cytoplasm, nucleoplasm, nucleus DNA binding Human GRHL2 HPA UniProtKB {GO:0005737=GO_REF:0000052, GO:0006355=GO_REF:0000037, GO:0005730=GO_REF:0000052, GO:0001843=GO_REF:0000019, GO:0005634=GO_REF:0000052, GO:0001701=GO_REF:0000019, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q6ISB3 Grainyhead-like protein 2 homolog protein 20101115 {GO:0005737=IDA, GO:0006355=IEA, GO:0005730=IDA, GO:0001843=IEA, GO:0005634=IDA, GO:0001701=IEA, GO:0003677=IEA, GO:0006351=IEA} in utero embryonic development, neural tube closure, regulation of transcription, DNA-dependent, transcription, DNA-dependent cytoplasm, nucleolus, nucleus DNA binding Human GRHL3 MGI UniProtKB {GO:0001736=GO_REF:0000019, GO:0007389=GO_REF:0000019, GO:0000981=GO_REF:0000019, GO:0090179=GO_REF:0000019, GO:0005634=GO_REF:0000039, GO:0007398=GO_REF:0000019, GO:0007417=GO_REF:0000019, GO:0003677=GO_REF:0000019, GO:0008544=GO_REF:0000019, GO:0032321=GO_REF:0000019, GO:0032956=PMID:20643356, GO:0045944=GO_REF:0000019, GO:0061029=GO_REF:0000019, GO:0042060=GO_REF:0000019, GO:0090103=GO_REF:0000019} Q8TE85 Grainyhead-like protein 3 homolog protein 20101206 {GO:0001736=IEA, GO:0007389=IEA, GO:0000981=IEA, GO:0090179=IEA, GO:0005634=IEA, GO:0007398=IEA, GO:0007417=IEA, GO:0003677=IEA, GO:0008544=IEA, GO:0032321=IEA, GO:0032956=IGI, GO:0045944=IEA, GO:0061029=IEA, GO:0042060=IEA, GO:0090103=IEA} central nervous system development, cochlea morphogenesis, ectoderm development, epidermis development, establishment of planar polarity, eyelid development in camera-type eye, pattern specification process, planar cell polarity pathway involved in neural tube closure, positive regulation of Rho GTPase activity, positive regulation of transcription from RNA polymerase II promoter, regulation of actin cytoskeleton organization, wound healing nucleus DNA binding, sequence-specific DNA binding RNA polymerase II transcription factor activity Human UniProtKB:Q8IW93 GRHPR LIFEdb UniProtKB {GO:0007588=PMID:10484776, GO:0048037=GO_REF:0000002, GO:0005782=Reactome:REACT_16910, GO:0008465=PMID:10484776, GO:0044281=Reactome:REACT_111217, GO:0016618=PMID:17510093, GO:0051259=PMID:16756993, GO:0070402=PMID:16756993, GO:0042803=PMID:16756993, GO:0016616=GO_REF:0000002, GO:0034641=Reactome:REACT_13, GO:0005737=GO_REF:0000054, GO:0051287=PMID:10484776, GO:0008152=PMID:10524214, GO:0046487=Reactome:REACT_16925, GO:0030267=PMID:10484776, GO:0055114=PMID:10484776} Q9UBQ7 Glyoxylate reductase/hydroxypyruvate reductase protein 20100607 {GO:0007588=IMP, GO:0048037=IEA, GO:0005782=TAS, GO:0008465=IDA, GO:0044281=TAS, GO:0016618=IDA, GO:0051259=IDA, GO:0070402=IDA, GO:0042803=IDA, GO:0016616=IEA, GO:0034641=TAS, GO:0005737=IDA, GO:0051287=TAS, GO:0008152=NAS, GO:0046487=TAS, GO:0030267=IDA, GO:0055114=IDA} cellular nitrogen compound metabolic process, excretion, glyoxylate metabolic process, metabolic process, oxidation-reduction process, protein oligomerization, small molecule metabolic process cytoplasm, peroxisomal matrix NAD binding, NADPH binding, cofactor binding, glycerate dehydrogenase activity, glyoxylate reductase (NADP) activity, hydroxypyruvate reductase activity, oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor, protein homodimerization activity Human GRIA1 BHF-UCL UniProtKB {GO:0005515=PMID:20805473, GO:0030054=GO_REF:0000037, GO:0005886=Reactome:REACT_20569, GO:0005234=GO_REF:0000002, GO:0007268=Reactome:REACT_13685, GO:0030425=GO_REF:0000024, GO:0031623=GO_REF:0000019, GO:0043197=GO_REF:0000024, GO:0045211=GO_REF:0000039, GO:0004971=PMID:20805473, GO:0032281=GO_REF:0000024, GO:0004970=GO_REF:0000002, GO:0015277=PMID:1311100, GO:0043025=GO_REF:0000024, GO:0007616=GO_REF:0000019, GO:0009986=GO_REF:0000024, GO:0014069=GO_REF:0000024, GO:0030165=GO_REF:0000024, GO:0044309=GO_REF:0000024, GO:0030666=Reactome:REACT_18330, GO:0007165=PMID:1311100, GO:0032590=GO_REF:0000019, GO:0030288=GO_REF:0000002, GO:0008066=PMID:1320959, GO:0005789=GO_REF:0000039, GO:0016021=GO_REF:0000038} P42261 Glutamate receptor 1 protein 20110218 {GO:0005515=IPI, GO:0030054=IEA, GO:0005886=TAS, GO:0005234=IEA, GO:0007268=TAS, GO:0030425=ISS, GO:0031623=IEA, GO:0043197=ISS, GO:0045211=IEA, GO:0004971=IDA, GO:0032281=ISS, GO:0004970=IEA, GO:0015277=TAS, GO:0043025=ISS, GO:0007616=IEA, GO:0009986=ISS, GO:0014069=ISS, GO:0030165=ISS, GO:0044309=ISS, GO:0030666=TAS, GO:0007165=TAS, GO:0032590=IEA, GO:0030288=IEA, GO:0008066=TAS, GO:0005789=IEA, GO:0016021=IEA} long-term memory, receptor internalization, signal transduction, synaptic transmission alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid selective glutamate receptor complex, cell junction, cell surface, dendrite, dendrite membrane, dendritic spine, endocytic vesicle membrane, endoplasmic reticulum membrane, integral to membrane, neuron spine, neuronal cell body, outer membrane-bounded periplasmic space, plasma membrane, postsynaptic density, postsynaptic membrane PDZ domain binding, alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity, extracellular-glutamate-gated ion channel activity, glutamate receptor activity, ionotropic glutamate receptor activity, kainate selective glutamate receptor activity, protein binding Human UniProtKB:P23818 GRIA2 Reactome UniProtKB {GO:0005215=GO_REF:0000002, GO:0030054=GO_REF:0000037, GO:0005886=Reactome:REACT_20569, GO:0005234=GO_REF:0000019, GO:0007268=Reactome:REACT_13685, GO:0030666=Reactome:REACT_18330, GO:0007165=PMID:8003671, GO:0035235=PMID:20614889, GO:0005887=GO_REF:0000024, GO:0004971=GO_REF:0000024, GO:0045211=GO_REF:0000039, GO:0030288=GO_REF:0000002, GO:0004970=PMID:20614889, GO:0032281=GO_REF:0000024, GO:0008066=PMID:1311100, GO:0005789=GO_REF:0000039, GO:0015277=GO_REF:0000024, GO:0016021=GO_REF:0000038} P42262 Glutamate receptor 2 protein 20130129 {GO:0005215=IEA, GO:0030054=IEA, GO:0005886=TAS, GO:0005234=IEA, GO:0007268=TAS, GO:0030666=TAS, GO:0007165=TAS, GO:0035235=IDA, GO:0005887=ISS, GO:0004971=ISS, GO:0045211=IEA, GO:0030288=IEA, GO:0004970=IDA, GO:0032281=ISS, GO:0008066=TAS, GO:0005789=IEA, GO:0015277=ISS, GO:0016021=IEA} ionotropic glutamate receptor signaling pathway, signal transduction, synaptic transmission alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid selective glutamate receptor complex, cell junction, endocytic vesicle membrane, endoplasmic reticulum membrane, integral to membrane, integral to plasma membrane, outer membrane-bounded periplasmic space, plasma membrane, postsynaptic membrane alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity, extracellular-glutamate-gated ion channel activity, glutamate receptor activity, ionotropic glutamate receptor activity, kainate selective glutamate receptor activity, transporter activity Human GRIA3 Reactome UniProtKB {GO:0030054=GO_REF:0000037, GO:0005886=Reactome:REACT_20569, GO:0005234=GO_REF:0000002, GO:0007268=Reactome:REACT_13685, GO:0007215=PMID:1709304, GO:0030666=Reactome:REACT_18393, GO:0016020=GO_REF:0000002, GO:0045211=GO_REF:0000039, GO:0004971=PMID:21172611, GO:0004970=GO_REF:0000002, GO:0032281=GO_REF:0000024, GO:0006810=PMID:1709304, GO:0016021=GO_REF:0000038} P42263 Glutamate receptor 3 protein 20130129 {GO:0030054=IEA, GO:0005886=TAS, GO:0005234=IEA, GO:0007268=TAS, GO:0007215=TAS, GO:0030666=TAS, GO:0016020=IEA, GO:0045211=IEA, GO:0004971=IDA, GO:0004970=IEA, GO:0032281=ISS, GO:0006810=TAS, GO:0016021=IEA} glutamate receptor signaling pathway, synaptic transmission, transport alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid selective glutamate receptor complex, cell junction, endocytic vesicle membrane, integral to membrane, membrane, plasma membrane, postsynaptic membrane alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity, extracellular-glutamate-gated ion channel activity, ionotropic glutamate receptor activity Human GRIA4 GOC UniProtKB {GO:0005215=GO_REF:0000002, GO:0030054=GO_REF:0000037, GO:0005886=Reactome:REACT_20569, GO:0005234=GO_REF:0000002, GO:0007268=Reactome:REACT_13685, GO:0007215=PMID:8589990, GO:0030425=GO_REF:0000039, GO:0030666=Reactome:REACT_18393, GO:0035235=GO_REF:0000024, GO:0032983=GO_REF:0000024, GO:0045211=GO_REF:0000039, GO:0030288=GO_REF:0000002, GO:0004971=PMID:21172611, GO:0032281=GO_REF:0000024, GO:0004970=GO_REF:0000024, GO:0006810=PMID:8589990, GO:0015277=GO_REF:0000024, GO:0016021=GO_REF:0000038} P48058 Glutamate receptor 4 protein 20130413 {GO:0005215=IEA, GO:0030054=IEA, GO:0005886=TAS, GO:0005234=IEA, GO:0007268=TAS, GO:0007215=TAS, GO:0030425=IEA, GO:0030666=TAS, GO:0035235=ISS, GO:0032983=ISS, GO:0045211=IEA, GO:0030288=IEA, GO:0004971=IDA, GO:0032281=ISS, GO:0004970=ISS, GO:0006810=TAS, GO:0015277=ISS, GO:0016021=IEA} glutamate receptor signaling pathway, ionotropic glutamate receptor signaling pathway, synaptic transmission, transport alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid selective glutamate receptor complex, cell junction, dendrite, endocytic vesicle membrane, integral to membrane, kainate selective glutamate receptor complex, outer membrane-bounded periplasmic space, plasma membrane, postsynaptic membrane alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity, extracellular-glutamate-gated ion channel activity, ionotropic glutamate receptor activity, kainate selective glutamate receptor activity, transporter activity Human UniProtKB:P19493 GRID1 UniProtKB UniProtKB {GO:0030054=GO_REF:0000037, GO:0005886=GO_REF:0000039, GO:0045211=GO_REF:0000039, GO:0030288=GO_REF:0000002, GO:0005234=GO_REF:0000002, GO:0004970=GO_REF:0000002, GO:0016021=GO_REF:0000037} Q9ULK0 Glutamate receptor ionotropic, delta-1 protein 20130413 {GO:0030054=IEA, GO:0005886=IEA, GO:0045211=IEA, GO:0030288=IEA, GO:0005234=IEA, GO:0004970=IEA, GO:0016021=IEA} cell junction, integral to membrane, outer membrane-bounded periplasmic space, plasma membrane, postsynaptic membrane extracellular-glutamate-gated ion channel activity, ionotropic glutamate receptor activity Human UniProtKB-SubCell:SL-0219 GRID2 BHF-UCL UniProtKB {GO:0030054=GO_REF:0000037, GO:0008328=GO_REF:0000024, GO:0005886=GO_REF:0000024, GO:0060134=GO_REF:0000024, GO:0005234=GO_REF:0000002, GO:0035249=GO_REF:0000024, GO:0060079=GO_REF:0000024, GO:0045202=GO_REF:0000024, GO:0007215=PMID:9465309, GO:0030165=GO_REF:0000024, GO:0043523=GO_REF:0000024, GO:0043197=GO_REF:0000024, GO:0005887=PMID:9465309, GO:0045211=GO_REF:0000039, GO:0030288=GO_REF:0000002, GO:0008066=PMID:9465309, GO:0097110=GO_REF:0000024, GO:0004970=GO_REF:0000002, GO:0006810=PMID:9465309, GO:0016021=GO_REF:0000038, GO:0034613=GO_REF:0000024} O43424 Glutamate receptor ionotropic, delta-2 protein 20120314 {GO:0030054=IEA, GO:0008328=ISS, GO:0005886=ISS, GO:0060134=ISS, GO:0005234=IEA, GO:0035249=ISS, GO:0060079=ISS, GO:0045202=ISS, GO:0007215=TAS, GO:0030165=ISS, GO:0043523=ISS, GO:0043197=ISS, GO:0005887=TAS, GO:0045211=IEA, GO:0030288=IEA, GO:0008066=TAS, GO:0097110=ISS, GO:0004970=IEA, GO:0006810=TAS, GO:0016021=IEA, GO:0034613=ISS} cellular protein localization, glutamate receptor signaling pathway, prepulse inhibition, regulation of excitatory postsynaptic membrane potential, regulation of neuron apoptotic process, synaptic transmission, glutamatergic, transport cell junction, dendritic spine, integral to membrane, integral to plasma membrane, ionotropic glutamate receptor complex, outer membrane-bounded periplasmic space, plasma membrane, postsynaptic membrane, synapse PDZ domain binding, extracellular-glutamate-gated ion channel activity, glutamate receptor activity, ionotropic glutamate receptor activity, scaffold protein binding Human UniProtKB:Q61625 GRID2IP InterPro UniProtKB {GO:0030054=GO_REF:0000037, GO:0030036=GO_REF:0000002, GO:0005886=GO_REF:0000037, GO:0045211=GO_REF:0000039, GO:0003779=GO_REF:0000002, GO:0060292=GO_REF:0000019} C9JNS8 Delphilin protein 20130413 {GO:0030054=IEA, GO:0030036=IEA, GO:0005886=IEA, GO:0045211=IEA, GO:0003779=IEA, GO:0060292=IEA} actin cytoskeleton organization, long term synaptic depression cell junction, plasma membrane, postsynaptic membrane actin binding Human InterPro:IPR003104 GRIK1 Reactome UniProtKB {GO:0030054=GO_REF:0000037, GO:0005886=Reactome:REACT_21414, GO:0005234=GO_REF:0000002, GO:0007268=Reactome:REACT_13685, GO:0014054=GO_REF:0000019, GO:0030425=GO_REF:0000019, GO:0045211=GO_REF:0000039, GO:0004970=GO_REF:0000002, GO:0015277=PMID:9335499, GO:0006810=PMID:8260617, GO:0030534=GO_REF:0000019, GO:0051966=PMID:9335499, GO:0051967=GO_REF:0000019, GO:0035249=GO_REF:0000019, GO:0060079=GO_REF:0000019, GO:0007215=PMID:8260617, GO:0007417=PMID:10580501, GO:0032230=GO_REF:0000019, GO:0007399=PMID:8260617, GO:0042734=GO_REF:0000019, GO:0032983=GO_REF:0000019, GO:0060080=GO_REF:0000019, GO:0005887=PMID:8260617, GO:0016021=GO_REF:0000038, GO:0048266=GO_REF:0000019} P39086 Glutamate receptor ionotropic, kainate 1 protein 20130213 {GO:0030054=IEA, GO:0005886=TAS, GO:0005234=IEA, GO:0007268=TAS, GO:0014054=IEA, GO:0030425=IEA, GO:0045211=IEA, GO:0004970=IEA, GO:0015277=IDA, GO:0006810=TAS, GO:0030534=IEA, GO:0051966=TAS, GO:0051967=IEA, GO:0035249=IEA, GO:0060079=IEA, GO:0007215=TAS, GO:0007417=TAS, GO:0032230=IEA, GO:0007399=TAS, GO:0042734=IEA, GO:0032983=IEA, GO:0060080=IEA, GO:0005887=TAS, GO:0016021=IEA, GO:0048266=IEA} adult behavior, behavioral response to pain, central nervous system development, glutamate receptor signaling pathway, negative regulation of synaptic transmission, glutamatergic, nervous system development, positive regulation of gamma-aminobutyric acid secretion, positive regulation of synaptic transmission, GABAergic, regulation of excitatory postsynaptic membrane potential, regulation of inhibitory postsynaptic membrane potential, regulation of synaptic transmission, glutamatergic, synaptic transmission, synaptic transmission, glutamatergic, transport cell junction, dendrite, integral to membrane, integral to plasma membrane, kainate selective glutamate receptor complex, plasma membrane, postsynaptic membrane, presynaptic membrane extracellular-glutamate-gated ion channel activity, ionotropic glutamate receptor activity, kainate selective glutamate receptor activity Human GRIK2 Reactome UniProtKB {GO:0030054=GO_REF:0000037, GO:0005886=Reactome:REACT_21414, GO:0005234=GO_REF:0000002, GO:0007268=Reactome:REACT_13685, GO:0006886=GO_REF:0000019, GO:0019228=GO_REF:0000019, GO:0005622=GO_REF:0000019, GO:0043524=GO_REF:0000019, GO:0045211=GO_REF:0000039, GO:0004970=GO_REF:0000019, GO:0048169=GO_REF:0000019, GO:0043025=GO_REF:0000019, GO:0015277=PMID:15537878, GO:0006810=PMID:7536611, GO:0001662=GO_REF:0000019, GO:0035249=GO_REF:0000019, GO:0006874=GO_REF:0000019, GO:0060079=GO_REF:0000019, GO:0050804=PMID:15537878, GO:0007215=PMID:7536611, GO:0042734=GO_REF:0000019, GO:0032983=GO_REF:0000019, GO:0060080=GO_REF:0000019, GO:0016020=GO_REF:0000002, GO:0005887=PMID:7536611, GO:0050806=PMID:15537878, GO:0048172=PMID:15537878} Q13002 Glutamate receptor ionotropic, kainate 2 protein 20130213 {GO:0030054=IEA, GO:0005886=TAS, GO:0005234=IEA, GO:0007268=TAS, GO:0006886=IEA, GO:0019228=IEA, GO:0005622=IEA, GO:0043524=IEA, GO:0045211=IEA, GO:0004970=IEA, GO:0048169=IEA, GO:0043025=IEA, GO:0015277=IDA, GO:0006810=NAS, GO:0001662=IEA, GO:0035249=IEA, GO:0006874=IEA, GO:0060079=IEA, GO:0050804=IDA, GO:0007215=TAS, GO:0042734=IEA, GO:0032983=IEA, GO:0060080=IEA, GO:0016020=IEA, GO:0005887=TAS, GO:0050806=IMP, GO:0048172=IMP} behavioral fear response, cellular calcium ion homeostasis, glutamate receptor signaling pathway, intracellular protein transport, negative regulation of neuron apoptotic process, positive regulation of synaptic transmission, regulation of action potential in neuron, regulation of excitatory postsynaptic membrane potential, regulation of inhibitory postsynaptic membrane potential, regulation of long-term neuronal synaptic plasticity, regulation of short-term neuronal synaptic plasticity, regulation of synaptic transmission, synaptic transmission, synaptic transmission, glutamatergic, transport cell junction, integral to plasma membrane, intracellular, kainate selective glutamate receptor complex, membrane, neuronal cell body, plasma membrane, postsynaptic membrane, presynaptic membrane extracellular-glutamate-gated ion channel activity, ionotropic glutamate receptor activity, kainate selective glutamate receptor activity Human GRIK3 GOC UniProtKB {GO:0030424=GO_REF:0000024, GO:0030054=GO_REF:0000037, GO:0005886=Reactome:REACT_21414, GO:0001640=PMID:9144652, GO:0005234=GO_REF:0000002, GO:0051967=GO_REF:0000024, GO:0007216=PMID:9144652, GO:0007268=Reactome:REACT_13685, GO:0007196=PMID:9144652, GO:0032839=GO_REF:0000024, GO:0007215=PMID:7719709, GO:0030425=GO_REF:0000024, GO:0035235=PMID:11124978, GO:0005887=PMID:7719709, GO:0043195=GO_REF:0000024, GO:0045211=GO_REF:0000039, GO:0004970=PMID:11124978, GO:0008066=PMID:8128318, GO:0042391=PMID:11124978, GO:0015277=PMID:7719709, GO:0043204=GO_REF:0000024, GO:0016021=GO_REF:0000038} Q13003 Glutamate receptor ionotropic, kainate 3 protein 20130413 {GO:0030424=ISS, GO:0030054=IEA, GO:0005886=TAS, GO:0001640=IDA, GO:0005234=IEA, GO:0051967=ISS, GO:0007216=IDA, GO:0007268=TAS, GO:0007196=IDA, GO:0032839=ISS, GO:0007215=IDA, GO:0030425=ISS, GO:0035235=IDA, GO:0005887=IDA, GO:0043195=ISS, GO:0045211=IEA, GO:0004970=IDA, GO:0008066=TAS, GO:0042391=IDA, GO:0015277=IDA, GO:0043204=ISS, GO:0016021=IEA} G-protein coupled glutamate receptor signaling pathway, adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway, glutamate receptor signaling pathway, ionotropic glutamate receptor signaling pathway, negative regulation of synaptic transmission, glutamatergic, regulation of membrane potential, synaptic transmission axon, cell junction, dendrite, dendrite cytoplasm, integral to membrane, integral to plasma membrane, perikaryon, plasma membrane, postsynaptic membrane, terminal bouton adenylate cyclase inhibiting G-protein coupled glutamate receptor activity, extracellular-glutamate-gated ion channel activity, glutamate receptor activity, ionotropic glutamate receptor activity, kainate selective glutamate receptor activity Human GRIK4 Reactome UniProtKB {GO:0042734=GO_REF:0000019, GO:0032983=GO_REF:0000019, GO:0030054=GO_REF:0000037, GO:0005886=Reactome:REACT_21414, GO:0005887=PMID:8263508, GO:0045211=GO_REF:0000039, GO:0005234=GO_REF:0000002, GO:0015277=PMID:8263508, GO:0006810=PMID:8263508, GO:0007268=Reactome:REACT_13685, GO:0007215=PMID:8263508} Q16099 Glutamate receptor ionotropic, kainate 4 protein 20100205 {GO:0042734=IEA, GO:0032983=IEA, GO:0030054=IEA, GO:0005886=TAS, GO:0005887=TAS, GO:0045211=IEA, GO:0005234=IEA, GO:0015277=TAS, GO:0006810=TAS, GO:0007268=TAS, GO:0007215=TAS} glutamate receptor signaling pathway, synaptic transmission, transport cell junction, integral to plasma membrane, kainate selective glutamate receptor complex, plasma membrane, postsynaptic membrane, presynaptic membrane extracellular-glutamate-gated ion channel activity, kainate selective glutamate receptor activity Human GRIK5 Reactome UniProtKB {GO:0017124=GO_REF:0000019, GO:0030054=GO_REF:0000037, GO:0005886=Reactome:REACT_21414, GO:0005234=GO_REF:0000002, GO:0060079=GO_REF:0000019, GO:0035249=GO_REF:0000019, GO:0007268=Reactome:REACT_13685, GO:0014069=GO_REF:0000019, GO:0030165=GO_REF:0000019, GO:0042802=GO_REF:0000019, GO:0042734=GO_REF:0000019, GO:0043525=GO_REF:0000019, GO:0032983=GO_REF:0000019, GO:0043195=GO_REF:0000019, GO:0045211=GO_REF:0000039, GO:0031630=GO_REF:0000019, GO:0015277=PMID:1321949, GO:0051649=GO_REF:0000019, GO:0043204=GO_REF:0000019, GO:0043113=GO_REF:0000019, GO:0016021=GO_REF:0000029, GO:0006621=GO_REF:0000019, GO:0071333=GO_REF:0000019} Q16478 Glutamate receptor ionotropic, kainate 5 protein 20091216 {GO:0017124=IEA, GO:0030054=IEA, GO:0005886=TAS, GO:0005234=IEA, GO:0060079=IEA, GO:0035249=IEA, GO:0007268=TAS, GO:0014069=IEA, GO:0030165=IEA, GO:0042802=IEA, GO:0042734=IEA, GO:0043525=IEA, GO:0032983=IEA, GO:0043195=IEA, GO:0045211=IEA, GO:0031630=IEA, GO:0015277=IDA, GO:0051649=IEA, GO:0043204=IEA, GO:0043113=IEA, GO:0016021=NAS, GO:0006621=IEA, GO:0071333=IEA} cellular response to glucose stimulus, establishment of localization in cell, positive regulation of neuron apoptotic process, protein retention in ER lumen, receptor clustering, regulation of excitatory postsynaptic membrane potential, regulation of synaptic vesicle fusion to presynaptic membrane, synaptic transmission, synaptic transmission, glutamatergic cell junction, integral to membrane, kainate selective glutamate receptor complex, perikaryon, plasma membrane, postsynaptic density, postsynaptic membrane, presynaptic membrane, terminal bouton PDZ domain binding, SH3 domain binding, extracellular-glutamate-gated ion channel activity, identical protein binding, kainate selective glutamate receptor activity Human GRIN1 UniProtKB UniProtKB {GO:0005515=PMID:17997397, GO:0005516=GO_REF:0000024, GO:0043005=GO_REF:0000024, GO:0030054=GO_REF:0000038, GO:0005886=GO_REF:0000038, GO:0045471=PMID:18445116, GO:0017146=PMID:17047094, GO:0005234=GO_REF:0000002, GO:0007268=Reactome:REACT_13685, GO:0045202=GO_REF:0000024, GO:0030425=PMID:10749211, GO:0055074=GO_REF:0000024, GO:0043197=GO_REF:0000024, GO:0004972=PMID:7679115, GO:0043195=GO_REF:0000024, GO:0045944=GO_REF:0000024, GO:0045211=GO_REF:0000038, GO:0004970=GO_REF:0000002, GO:0042391=PMID:7679115, GO:0042165=GO_REF:0000024, GO:0006812=PMID:7685113, GO:0005262=PMID:7685113, GO:2000463=GO_REF:0000024, GO:0009986=GO_REF:0000024, GO:0005509=GO_REF:0000024, GO:0060079=GO_REF:0000024, GO:0014069=GO_REF:0000024, GO:0043083=GO_REF:0000024, GO:0060076=GO_REF:0000024, GO:0008021=GO_REF:0000024, GO:0035235=GO_REF:0000024, GO:0005887=PMID:7685113, GO:0030288=GO_REF:0000002, GO:0008542=GO_REF:0000024, GO:0070588=PMID:7685113, GO:0016594=PMID:17047094, GO:0016595=PMID:7685113, GO:0016021=GO_REF:0000038} Q5VSF9 Glutamate receptor ionotropic, NMDA 1 protein 20130413 {GO:0005515=IPI, GO:0005516=ISS, GO:0043005=ISS, GO:0030054=IEA, GO:0005886=IEA, GO:0045471=IDA, GO:0017146=IDA, GO:0005234=IEA, GO:0007268=TAS, GO:0045202=ISS, GO:0030425=IDA, GO:0055074=ISS, GO:0043197=ISS, GO:0004972=IDA, GO:0043195=ISS, GO:0045944=ISS, GO:0045211=IEA, GO:0004970=IEA, GO:0042391=IDA, GO:0042165=ISS, GO:0006812=IDA, GO:0005262=IDA, GO:2000463=ISS, GO:0009986=ISS, GO:0005509=ISS, GO:0060079=ISS, GO:0014069=ISS, GO:0043083=ISS, GO:0060076=ISS, GO:0008021=ISS, GO:0035235=ISS, GO:0005887=IDA, GO:0030288=IEA, GO:0008542=ISS, GO:0070588=IDA, GO:0016594=IMP, GO:0016595=IDA, GO:0016021=IEA} calcium ion homeostasis, calcium ion transmembrane transport, cation transport, ionotropic glutamate receptor signaling pathway, positive regulation of excitatory postsynaptic membrane potential, positive regulation of transcription from RNA polymerase II promoter, regulation of excitatory postsynaptic membrane potential, regulation of membrane potential, response to ethanol, synaptic transmission, visual learning N-methyl-D-aspartate selective glutamate receptor complex, cell junction, cell surface, dendrite, dendritic spine, excitatory synapse, integral to membrane, integral to plasma membrane, neuron projection, outer membrane-bounded periplasmic space, plasma membrane, postsynaptic density, postsynaptic membrane, synapse, synaptic cleft, synaptic vesicle, terminal bouton N-methyl-D-aspartate selective glutamate receptor activity, calcium channel activity, calcium ion binding, calmodulin binding, extracellular-glutamate-gated ion channel activity, glutamate binding, glycine binding, ionotropic glutamate receptor activity, neurotransmitter binding, protein binding Human UniProtKB-KW:KW-0628 GRIN2A BHF-UCL UniProtKB {GO:0005515=PMID:17997397, GO:0030054=GO_REF:0000037, GO:0005886=Reactome:REACT_20670, GO:0045471=PMID:18445116, GO:0017146=PMID:10480938, GO:0005234=GO_REF:0000002, GO:0007268=Reactome:REACT_13685, GO:0001964=GO_REF:0000019, GO:0008104=GO_REF:0000019, GO:0042417=GO_REF:0000019, GO:0048167=GO_REF:0000019, GO:0004972=GO_REF:0000019, GO:0045211=GO_REF:0000039, GO:0004970=GO_REF:0000002, GO:0007611=PMID:7816096, GO:0006810=PMID:8768735, GO:0007613=GO_REF:0000019, GO:0022008=GO_REF:0000019, GO:0005262=GO_REF:0000019, GO:0043065=GO_REF:0000019, GO:0009986=GO_REF:0000024, GO:0033058=GO_REF:0000019, GO:0042177=GO_REF:0000019, GO:0042493=GO_REF:0000019, GO:0060079=GO_REF:0000019, GO:0009611=GO_REF:0000019, GO:0014069=GO_REF:0000019, GO:0030431=GO_REF:0000019, GO:0007215=PMID:8768735, GO:0019233=GO_REF:0000019, GO:0042428=GO_REF:0000019, GO:0042734=GO_REF:0000019, GO:0001975=GO_REF:0000019, GO:0005887=PMID:8768735, GO:0030288=GO_REF:0000002, GO:0008542=GO_REF:0000019, GO:0008270=GO_REF:0000024, GO:0016021=GO_REF:0000038, GO:0051930=GO_REF:0000019} Q12879 Glutamate receptor ionotropic, NMDA 2A protein 20120316 {GO:0005515=IPI, GO:0030054=IEA, GO:0005886=TAS, GO:0045471=IDA, GO:0017146=IDA, GO:0005234=IEA, GO:0007268=TAS, GO:0001964=IEA, GO:0008104=IEA, GO:0042417=IEA, GO:0048167=IEA, GO:0004972=IEA, GO:0045211=IEA, GO:0004970=IEA, GO:0007611=TAS, GO:0006810=TAS, GO:0007613=IEA, GO:0022008=IEA, GO:0005262=IEA, GO:0043065=IEA, GO:0009986=ISS, GO:0033058=IEA, GO:0042177=IEA, GO:0042493=IEA, GO:0060079=IEA, GO:0009611=IEA, GO:0014069=IEA, GO:0030431=IEA, GO:0007215=TAS, GO:0019233=IEA, GO:0042428=IEA, GO:0042734=IEA, GO:0001975=IEA, GO:0005887=TAS, GO:0030288=IEA, GO:0008542=IEA, GO:0008270=ISS, GO:0016021=IEA, GO:0051930=IEA} directional locomotion, dopamine metabolic process, glutamate receptor signaling pathway, learning or memory, memory, negative regulation of protein catabolic process, neurogenesis, positive regulation of apoptotic process, protein localization, regulation of excitatory postsynaptic membrane potential, regulation of sensory perception of pain, regulation of synaptic plasticity, response to amphetamine, response to drug, response to ethanol, response to wounding, sensory perception of pain, serotonin metabolic process, sleep, startle response, synaptic transmission, transport, visual learning N-methyl-D-aspartate selective glutamate receptor complex, cell junction, cell surface, integral to membrane, integral to plasma membrane, outer membrane-bounded periplasmic space, plasma membrane, postsynaptic density, postsynaptic membrane, presynaptic membrane N-methyl-D-aspartate selective glutamate receptor activity, calcium channel activity, extracellular-glutamate-gated ion channel activity, ionotropic glutamate receptor activity, protein binding, zinc ion binding Human UniProtKB:P35436 GRIN2B BHF-UCL UniProtKB {GO:0005515=PMID:17997397, GO:0030054=GO_REF:0000037, GO:0005886=Reactome:REACT_20670, GO:0005234=GO_REF:0000002, GO:0017146=PMID:17047094, GO:0045471=PMID:18445116, GO:0007268=Reactome:REACT_13685, GO:0001964=GO_REF:0000019, GO:0001967=GO_REF:0000019, GO:0004972=GO_REF:0000019, GO:0048167=GO_REF:0000019, GO:0045211=GO_REF:0000039, GO:0007611=PMID:10485705, GO:0006810=PMID:8768735, GO:0007613=GO_REF:0000019, GO:0001662=GO_REF:0000019, GO:0050966=GO_REF:0000019, GO:0007612=GO_REF:0000019, GO:0005262=GO_REF:0000019, GO:0009986=GO_REF:0000024, GO:0060079=GO_REF:0000019, GO:0014069=GO_REF:0000019, GO:0007215=PMID:8768735, GO:0001701=GO_REF:0000019, GO:0008021=GO_REF:0000019, GO:0007423=GO_REF:0000019, GO:0005887=PMID:8768735, GO:0030288=GO_REF:0000002, GO:0016594=PMID:17047094, GO:0008270=GO_REF:0000024, GO:0048266=GO_REF:0000019} Q13224 Glutamate receptor ionotropic, NMDA 2B protein 20120316 {GO:0005515=IPI, GO:0030054=IEA, GO:0005886=TAS, GO:0005234=IEA, GO:0017146=IDA, GO:0045471=IDA, GO:0007268=TAS, GO:0001964=IEA, GO:0001967=IEA, GO:0004972=IEA, GO:0048167=IEA, GO:0045211=IEA, GO:0007611=TAS, GO:0006810=TAS, GO:0007613=IEA, GO:0001662=IEA, GO:0050966=IEA, GO:0007612=IEA, GO:0005262=IEA, GO:0009986=ISS, GO:0060079=IEA, GO:0014069=IEA, GO:0007215=TAS, GO:0001701=IEA, GO:0008021=IEA, GO:0007423=IEA, GO:0005887=TAS, GO:0030288=IEA, GO:0016594=IDA, GO:0008270=ISS, GO:0048266=IEA} behavioral fear response, behavioral response to pain, detection of mechanical stimulus involved in sensory perception of pain, glutamate receptor signaling pathway, in utero embryonic development, learning, learning or memory, memory, regulation of excitatory postsynaptic membrane potential, regulation of synaptic plasticity, response to ethanol, sensory organ development, startle response, suckling behavior, synaptic transmission, transport N-methyl-D-aspartate selective glutamate receptor complex, cell junction, cell surface, integral to plasma membrane, outer membrane-bounded periplasmic space, plasma membrane, postsynaptic density, postsynaptic membrane, synaptic vesicle N-methyl-D-aspartate selective glutamate receptor activity, calcium channel activity, extracellular-glutamate-gated ion channel activity, glycine binding, protein binding, zinc ion binding Human UniProtKB:Q01097 GRIN2C HPA UniProtKB {GO:0030054=GO_REF:0000037, GO:0005261=GO_REF:0000019, GO:0005886=GO_REF:0000052, GO:0042177=GO_REF:0000019, GO:0033058=GO_REF:0000019, GO:0005234=GO_REF:0000002, GO:0017146=GO_REF:0000019, GO:0060079=GO_REF:0000019, GO:0009611=GO_REF:0000019, GO:0007268=Reactome:REACT_13685, GO:0014069=GO_REF:0000019, GO:0007215=PMID:9798920, GO:0030165=GO_REF:0000019, GO:0005737=GO_REF:0000052, GO:0047485=GO_REF:0000019, GO:0008104=GO_REF:0000019, GO:0005887=PMID:9798920, GO:0004972=GO_REF:0000019, GO:0030288=GO_REF:0000002, GO:0045211=GO_REF:0000039, GO:0004970=GO_REF:0000002, GO:0006810=PMID:9798920, GO:0050885=GO_REF:0000019, GO:0016021=GO_REF:0000038} Q14957 Glutamate receptor ionotropic, NMDA 2C protein 20110516 {GO:0030054=IEA, GO:0005261=IEA, GO:0005886=IDA, GO:0042177=IEA, GO:0033058=IEA, GO:0005234=IEA, GO:0017146=IEA, GO:0060079=IEA, GO:0009611=IEA, GO:0007268=TAS, GO:0014069=IEA, GO:0007215=TAS, GO:0030165=IEA, GO:0005737=IDA, GO:0047485=IEA, GO:0008104=IEA, GO:0005887=TAS, GO:0004972=IEA, GO:0030288=IEA, GO:0045211=IEA, GO:0004970=IEA, GO:0006810=TAS, GO:0050885=IEA, GO:0016021=IEA} directional locomotion, glutamate receptor signaling pathway, negative regulation of protein catabolic process, neuromuscular process controlling balance, protein localization, regulation of excitatory postsynaptic membrane potential, response to wounding, synaptic transmission, transport N-methyl-D-aspartate selective glutamate receptor complex, cell junction, cytoplasm, integral to membrane, integral to plasma membrane, outer membrane-bounded periplasmic space, plasma membrane, postsynaptic density, postsynaptic membrane N-methyl-D-aspartate selective glutamate receptor activity, PDZ domain binding, cation channel activity, extracellular-glutamate-gated ion channel activity, ionotropic glutamate receptor activity, protein N-terminus binding Human GRIN2D Reactome UniProtKB {GO:0001964=GO_REF:0000019, GO:0007165=PMID:9480759, GO:0008344=GO_REF:0000019, GO:0030054=GO_REF:0000037, GO:0005886=Reactome:REACT_20670, GO:0004972=GO_REF:0000019, GO:0045211=GO_REF:0000039, GO:0030288=GO_REF:0000002, GO:0005234=GO_REF:0000002, GO:0007268=Reactome:REACT_13685, GO:0016021=GO_REF:0000037, GO:0051930=GO_REF:0000019} O15399 Glutamate receptor ionotropic, NMDA 2D protein 20130301 {GO:0001964=IEA, GO:0007165=NAS, GO:0008344=IEA, GO:0030054=IEA, GO:0005886=TAS, GO:0004972=IEA, GO:0045211=IEA, GO:0030288=IEA, GO:0005234=IEA, GO:0007268=TAS, GO:0016021=IEA, GO:0051930=IEA} adult locomotory behavior, regulation of sensory perception of pain, signal transduction, startle response, synaptic transmission cell junction, integral to membrane, outer membrane-bounded periplasmic space, plasma membrane, postsynaptic membrane N-methyl-D-aspartate selective glutamate receptor activity, extracellular-glutamate-gated ion channel activity Human GRIN3A UniProtKB UniProtKB {GO:0005515=PMID:17658481, GO:0043005=PMID:17658481, GO:0005262=GO_REF:0000019, GO:0030054=GO_REF:0000037, GO:0017146=PMID:17997397, GO:0045471=PMID:18445116, GO:0005234=GO_REF:0000002, GO:0060134=GO_REF:0000019, GO:0014069=GO_REF:0000039, GO:0045202=PMID:17658481, GO:0016358=GO_REF:0000019, GO:0042802=PMID:17997397, GO:0016020=PMID:17997397, GO:0004972=GO_REF:0000024, GO:0030288=GO_REF:0000002, GO:0045211=GO_REF:0000039, GO:0016594=PMID:17320117, GO:0043025=PMID:17658481, GO:0042165=GO_REF:0000019, GO:0006816=GO_REF:0000024, GO:0016021=PMID:11880201, GO:0048511=GO_REF:0000019, GO:0051721=GO_REF:0000024} Q8TCU5 Glutamate receptor ionotropic, NMDA 3A protein 20080704 {GO:0005515=IPI, GO:0043005=IDA, GO:0005262=IEA, GO:0030054=IEA, GO:0017146=IDA, GO:0045471=IDA, GO:0005234=IEA, GO:0060134=IEA, GO:0014069=IEA, GO:0045202=IDA, GO:0016358=IEA, GO:0042802=IPI, GO:0016020=IDA, GO:0004972=ISS, GO:0030288=IEA, GO:0045211=IEA, GO:0016594=IDA, GO:0043025=IDA, GO:0042165=IEA, GO:0006816=ISS, GO:0016021=NAS, GO:0048511=IEA, GO:0051721=ISS} calcium ion transport, dendrite development, prepulse inhibition, response to ethanol, rhythmic process N-methyl-D-aspartate selective glutamate receptor complex, cell junction, integral to membrane, membrane, neuron projection, neuronal cell body, outer membrane-bounded periplasmic space, postsynaptic density, postsynaptic membrane, synapse N-methyl-D-aspartate selective glutamate receptor activity, calcium channel activity, extracellular-glutamate-gated ion channel activity, glycine binding, identical protein binding, neurotransmitter binding, protein binding, protein phosphatase 2A binding Human UniProtKB:Q66K74 GRIN3B GOC UniProtKB {GO:0005262=PMID:11735224, GO:0030054=GO_REF:0000037, GO:0005261=GO_REF:0000024, GO:0005234=GO_REF:0000002, GO:0017146=PMID:11735224, GO:0030594=GO_REF:0000024, GO:0051205=PMID:11735224, GO:0007268=GO_REF:0000024, GO:0035235=GO_REF:0000024, GO:0030288=GO_REF:0000002, GO:0045211=GO_REF:0000039, GO:0004970=GO_REF:0000002, GO:0016594=GO_REF:0000024, GO:0043025=PMID:11735224, GO:0051924=PMID:11735224, GO:0042165=GO_REF:0000024} O60391 Glutamate receptor ionotropic, NMDA 3B protein 20130413 {GO:0005262=ISS, GO:0030054=IEA, GO:0005261=ISS, GO:0005234=IEA, GO:0017146=ISS, GO:0030594=ISS, GO:0051205=ISS, GO:0007268=ISS, GO:0035235=ISS, GO:0030288=IEA, GO:0045211=IEA, GO:0004970=IEA, GO:0016594=ISS, GO:0043025=ISS, GO:0051924=ISS, GO:0042165=ISS} ionotropic glutamate receptor signaling pathway, protein insertion into membrane, regulation of calcium ion transport, synaptic transmission N-methyl-D-aspartate selective glutamate receptor complex, cell junction, neuronal cell body, outer membrane-bounded periplasmic space, postsynaptic membrane calcium channel activity, cation channel activity, extracellular-glutamate-gated ion channel activity, glycine binding, ionotropic glutamate receptor activity, neurotransmitter binding, neurotransmitter receptor activity Human UniProtKB:Q8VHN2 GRIP1 BHF-UCL UniProtKB {GO:0043005=GO_REF:0000024, GO:0030054=GO_REF:0000037, GO:0008013=PMID:16344550, GO:0005886=GO_REF:0000024, GO:0005783=GO_REF:0000039, GO:0003713=PMID:15572661, GO:0007268=Reactome:REACT_13685, GO:0030159=PMID:10197531, GO:0050681=PMID:15572661, GO:0008022=PMID:16344550, GO:0005829=Reactome:REACT_18330, GO:0035556=PMID:10197531, GO:0008104=GO_REF:0000019, GO:0045211=GO_REF:0000039, GO:0016023=GO_REF:0000039, GO:0045121=GO_REF:0000019, GO:0045893=PMID:15572661, GO:0030521=PMID:15572661} Q9Y3R0 Glutamate receptor-interacting protein 1 protein 20120815 {GO:0043005=ISS, GO:0030054=IEA, GO:0008013=TAS, GO:0005886=ISS, GO:0005783=IEA, GO:0003713=NAS, GO:0007268=TAS, GO:0030159=NAS, GO:0050681=NAS, GO:0008022=IPI, GO:0005829=TAS, GO:0035556=NAS, GO:0008104=IEA, GO:0045211=IEA, GO:0016023=IEA, GO:0045121=IEA, GO:0045893=NAS, GO:0030521=NAS} androgen receptor signaling pathway, intracellular signal transduction, positive regulation of transcription, DNA-dependent, protein localization, synaptic transmission cell junction, cytoplasmic membrane-bounded vesicle, cytosol, endoplasmic reticulum, membrane raft, neuron projection, plasma membrane, postsynaptic membrane androgen receptor binding, beta-catenin binding, protein C-terminus binding, receptor signaling complex scaffold activity, transcription coactivator activity Human UniProtKB:Q925T6 GRIP2 Reactome UniProtKB {GO:0005886=Reactome:REACT_18330, GO:0007268=Reactome:REACT_13685, GO:0005829=Reactome:REACT_18330} Q9C0E4 Glutamate receptor-interacting protein 2 protein 20130301 {GO:0005886=TAS, GO:0007268=TAS, GO:0005829=TAS} synaptic transmission cytosol, plasma membrane Human GRIPAP1 UniProtKB UniProtKB {GO:0003674=GO_REF:0000015, GO:0008150=GO_REF:0000015, GO:0005575=GO_REF:0000015, GO:0005769=GO_REF:0000039} Q4V328 GRIP1-associated protein 1 protein 20061106 {GO:0003674=ND, GO:0008150=ND, GO:0005575=ND, GO:0005769=IEA} biological_process cellular_component, early endosome molecular_function Human GRK1 PINC UniProtKB {GO:0006915=GO_REF:0000019, GO:0038032=GO_REF:0000002, GO:0022400=PMID:15946941, GO:0050254=PMID:15946941, GO:0005524=GO_REF:0000037, GO:0008277=PMID:1656454, GO:0004672=PMID:9147475, GO:0004703=GO_REF:0000002, GO:0046777=PMID:15946941, GO:0016020=GO_REF:0000039, GO:0004674=GO_REF:0000038, GO:0009416=GO_REF:0000019, GO:0060060=GO_REF:0000019, GO:0008594=GO_REF:0000019, GO:0007601=GO_REF:0000037, GO:0016056=PMID:9147475, GO:0042327=GO_REF:0000019} Q15835 Rhodopsin kinase protein 20030904 {GO:0006915=IEA, GO:0038032=IEA, GO:0022400=IDA, GO:0050254=IDA, GO:0005524=IEA, GO:0008277=TAS, GO:0004672=TAS, GO:0004703=IEA, GO:0046777=IMP, GO:0016020=IEA, GO:0004674=IEA, GO:0009416=IEA, GO:0060060=IEA, GO:0008594=IEA, GO:0007601=IEA, GO:0016056=TAS, GO:0042327=IEA} apoptotic process, photoreceptor cell morphogenesis, positive regulation of phosphorylation, post-embryonic retina morphogenesis in camera-type eye, protein autophosphorylation, regulation of G-protein coupled receptor protein signaling pathway, regulation of rhodopsin mediated signaling pathway, response to light stimulus, rhodopsin mediated signaling pathway, termination of G-protein coupled receptor signaling pathway, visual perception membrane ATP binding, G-protein coupled receptor kinase activity, protein kinase activity, protein serine/threonine kinase activity, rhodopsin kinase activity Human GRK4 PINC UniProtKB {GO:0031623=PMID:20074556, GO:0007165=GO_REF:0000002, GO:0008277=PMID:1338872, GO:0004703=GO_REF:0000003, GO:0043025=GO_REF:0000019, GO:0038032=GO_REF:0000002, GO:0050254=GO_REF:0000019, GO:0005938=GO_REF:0000039, GO:0005524=GO_REF:0000037, GO:0030425=GO_REF:0000019, GO:0002031=GO_REF:0000019, GO:0005829=GO_REF:0000019} P32298 G protein-coupled receptor kinase 4 protein 20030904 {GO:0031623=IDA, GO:0007165=IEA, GO:0008277=TAS, GO:0004703=IEA, GO:0043025=IEA, GO:0038032=IEA, GO:0050254=IEA, GO:0005938=IEA, GO:0005524=IEA, GO:0030425=IEA, GO:0002031=IEA, GO:0005829=IEA} G-protein coupled receptor internalization, receptor internalization, regulation of G-protein coupled receptor protein signaling pathway, signal transduction, termination of G-protein coupled receptor signaling pathway cell cortex, cytosol, dendrite, neuronal cell body ATP binding, G-protein coupled receptor kinase activity, rhodopsin kinase activity Human GRK5 BHF-UCL UniProtKB {GO:0005515=PMID:17986524, GO:0043066=PMID:20124405, GO:0005886=PMID:17986524, GO:0007217=PMID:17986524, GO:0038032=GO_REF:0000002, GO:0006915=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0005524=GO_REF:0000037, GO:0007165=GO_REF:0000002, GO:0005737=GO_REF:0000039, GO:0008277=PMID:8288567, GO:0005543=PMID:9813065, GO:0004703=GO_REF:0000003, GO:0046777=PMID:14976207, GO:0004674=PMID:20124405, GO:0005080=PMID:9813065, GO:0007188=PMID:8626574, GO:0016055=GO_REF:0000037} P34947 G protein-coupled receptor kinase 5 protein 20080206 {GO:0005515=IPI, GO:0043066=IDA, GO:0005886=IDA, GO:0007217=IDA, GO:0038032=IEA, GO:0006915=IEA, GO:0005634=IEA, GO:0005524=IEA, GO:0007165=IEA, GO:0005737=IEA, GO:0008277=TAS, GO:0005543=TAS, GO:0004703=IEA, GO:0046777=IDA, GO:0004674=IDA, GO:0005080=TAS, GO:0007188=TAS, GO:0016055=IEA} Wnt receptor signaling pathway, adenylate cyclase-modulating G-protein coupled receptor signaling pathway, apoptotic process, negative regulation of apoptotic process, protein autophosphorylation, regulation of G-protein coupled receptor protein signaling pathway, signal transduction, tachykinin receptor signaling pathway, termination of G-protein coupled receptor signaling pathway cytoplasm, nucleus, plasma membrane ATP binding, G-protein coupled receptor kinase activity, phospholipid binding, protein binding, protein kinase C binding, protein serine/threonine kinase activity Human GRK6 PINC UniProtKB {GO:0007165=GO_REF:0000002, GO:0008277=PMID:8077221, GO:0004703=GO_REF:0000003, GO:0016020=GO_REF:0000039, GO:0038032=GO_REF:0000002, GO:0016055=GO_REF:0000037, GO:0005524=GO_REF:0000037} P43250 G protein-coupled receptor kinase 6 protein 20030904 {GO:0007165=IEA, GO:0008277=TAS, GO:0004703=IEA, GO:0016020=IEA, GO:0038032=IEA, GO:0016055=IEA, GO:0005524=IEA} Wnt receptor signaling pathway, regulation of G-protein coupled receptor protein signaling pathway, signal transduction, termination of G-protein coupled receptor signaling pathway membrane ATP binding, G-protein coupled receptor kinase activity Human GRK7 UniProtKB UniProtKB {GO:0007165=GO_REF:0000002, GO:0046777=PMID:15946941, GO:0004703=GO_REF:0000003, GO:0016020=GO_REF:0000039, GO:0038032=GO_REF:0000002, GO:0050254=PMID:15946941, GO:0007601=GO_REF:0000037, GO:0005524=GO_REF:0000037} Q8WTQ7 G protein-coupled receptor kinase 7 protein 20110719 {GO:0007165=IEA, GO:0046777=IMP, GO:0004703=IEA, GO:0016020=IEA, GO:0038032=IEA, GO:0050254=IDA, GO:0007601=IEA, GO:0005524=IEA} protein autophosphorylation, signal transduction, termination of G-protein coupled receptor signaling pathway, visual perception membrane ATP binding, G-protein coupled receptor kinase activity, rhodopsin kinase activity Human GRM1 Reactome UniProtKB {GO:0008219=GO_REF:0000037, GO:0005886=Reactome:REACT_18380, GO:0004930=PMID:7476890, GO:0007268=PMID:9076744, GO:0014069=GO_REF:0000019, GO:0005634=GO_REF:0000019, GO:0019233=GO_REF:0000019, GO:0000187=GO_REF:0000019, GO:0000186=GO_REF:0000019, GO:0071257=GO_REF:0000019, GO:0007186=PMID:7476890, GO:0005887=PMID:7476890, GO:0008066=PMID:7476890, GO:0007626=GO_REF:0000019, GO:0016021=GO_REF:0000038, GO:0051930=GO_REF:0000019} Q13255 Metabotropic glutamate receptor 1 protein 20090512 {GO:0008219=IEA, GO:0005886=TAS, GO:0004930=TAS, GO:0007268=TAS, GO:0014069=IEA, GO:0005634=IEA, GO:0019233=IEA, GO:0000187=IEA, GO:0000186=IEA, GO:0071257=IEA, GO:0007186=TAS, GO:0005887=TAS, GO:0008066=TAS, GO:0007626=IEA, GO:0016021=IEA, GO:0051930=IEA} G-protein coupled receptor signaling pathway, activation of MAPK activity, activation of MAPKK activity, cell death, cellular response to electrical stimulus, locomotory behavior, regulation of sensory perception of pain, sensory perception of pain, synaptic transmission integral to membrane, integral to plasma membrane, nucleus, plasma membrane, postsynaptic density G-protein coupled receptor activity, glutamate receptor activity Human GRM2 Reactome UniProtKB {GO:0030424=GO_REF:0000019, GO:0005886=Reactome:REACT_18380, GO:0005246=GO_REF:0000019, GO:0004930=PMID:7620613, GO:0001641=GO_REF:0000019, GO:0007268=PMID:7620613, GO:0007194=PMID:7620613, GO:0014047=GO_REF:0000019, GO:0005622=GO_REF:0000019, GO:0042734=GO_REF:0000019, GO:0005887=PMID:7620613, GO:0008066=PMID:7620613, GO:0016021=GO_REF:0000002} Q14416 Metabotropic glutamate receptor 2 protein 20090512 {GO:0030424=IEA, GO:0005886=TAS, GO:0005246=IEA, GO:0004930=TAS, GO:0001641=IEA, GO:0007268=TAS, GO:0007194=TAS, GO:0014047=IEA, GO:0005622=IEA, GO:0042734=IEA, GO:0005887=TAS, GO:0008066=TAS, GO:0016021=IEA} glutamate secretion, negative regulation of adenylate cyclase activity, synaptic transmission axon, integral to membrane, integral to plasma membrane, intracellular, plasma membrane, presynaptic membrane G-protein coupled receptor activity, calcium channel regulator activity, glutamate receptor activity, group II metabotropic glutamate receptor activity Human GRM3 InterPro UniProtKB {GO:0030424=GO_REF:0000019, GO:0005886=Reactome:REACT_18380, GO:0004930=GO_REF:0000002, GO:0005246=GO_REF:0000019, GO:0001641=GO_REF:0000019, GO:0007268=PMID:8840013, GO:0014069=GO_REF:0000019, GO:0050804=GO_REF:0000019, GO:0007194=PMID:8840013, GO:0042734=GO_REF:0000019, GO:0005887=PMID:8840013, GO:0045211=GO_REF:0000019, GO:0008066=PMID:8840013, GO:0016021=GO_REF:0000002} Q2PNZ6 Metabotropic glutamate receptor 3 protein 20130413 {GO:0030424=IEA, GO:0005886=TAS, GO:0004930=IEA, GO:0005246=IEA, GO:0001641=IEA, GO:0007268=TAS, GO:0014069=IEA, GO:0050804=IEA, GO:0007194=TAS, GO:0042734=IEA, GO:0005887=TAS, GO:0045211=IEA, GO:0008066=TAS, GO:0016021=IEA} negative regulation of adenylate cyclase activity, regulation of synaptic transmission, synaptic transmission axon, integral to membrane, integral to plasma membrane, plasma membrane, postsynaptic density, postsynaptic membrane, presynaptic membrane G-protein coupled receptor activity, calcium channel regulator activity, glutamate receptor activity, group II metabotropic glutamate receptor activity Human InterPro:IPR000162|InterPro:IPR000337|InterPro:IPR001234|InterPro:IPR017979 GRM4 UniProtKB UniProtKB {GO:0005886=GO_REF:0000040, GO:0004930=GO_REF:0000038, GO:0007268=PMID:8738157, GO:0007196=PMID:15102938, GO:0031410=PMID:15102938, GO:0007269=PMID:15102938, GO:0005622=PMID:15102938, GO:0043523=PMID:15102938, GO:0000187=PMID:15102938, GO:0043198=GO_REF:0000019, GO:0005887=PMID:15102938, GO:0043195=GO_REF:0000019, GO:0008066=PMID:9473604, GO:0016021=GO_REF:0000038, GO:0007612=GO_REF:0000019, GO:0043410=PMID:15102938, GO:0048787=GO_REF:0000019} Q6ZMQ2 cDNA FLJ16766 fis, clone BRAWH3013197, highly similar to Metabotropic glutamate receptor 4 protein 20130413 {GO:0005886=IEA, GO:0004930=IEA, GO:0007268=TAS, GO:0007196=IMP, GO:0031410=IDA, GO:0007269=TAS, GO:0005622=IDA, GO:0043523=TAS, GO:0000187=IDA, GO:0043198=IEA, GO:0005887=IDA, GO:0043195=IEA, GO:0008066=TAS, GO:0016021=IEA, GO:0007612=IEA, GO:0043410=IEP, GO:0048787=IEA} activation of MAPK activity, adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway, learning, neurotransmitter secretion, positive regulation of MAPK cascade, regulation of neuron apoptotic process, synaptic transmission cytoplasmic vesicle, dendritic shaft, integral to membrane, integral to plasma membrane, intracellular, plasma membrane, presynaptic active zone membrane, terminal bouton G-protein coupled receptor activity, glutamate receptor activity Human UniProtKB-SubCell:SL-0039 GRM5 UniProtKB UniProtKB {GO:0006355=GO_REF:0000019, GO:0005886=GO_REF:0000040, GO:0004930=GO_REF:0000038, GO:0031687=GO_REF:0000019, GO:0007268=GO_REF:0000019, GO:0014069=GO_REF:0000019, GO:0007205=GO_REF:0000019, GO:0007206=PMID:7908515, GO:0005737=GO_REF:0000019, GO:0000185=GO_REF:0000019, GO:0005887=PMID:7908515, GO:0043198=GO_REF:0000019, GO:0040013=GO_REF:0000019, GO:0002029=GO_REF:0000019, GO:0008066=PMID:7908515, GO:0006468=GO_REF:0000019, GO:0007626=GO_REF:0000019, GO:0016021=GO_REF:0000038, GO:0007612=GO_REF:0000019, GO:0048170=GO_REF:0000019} Q6J164 Metabotropic glutamate receptor 5 protein 20130413 {GO:0006355=IEA, GO:0005886=IEA, GO:0004930=IEA, GO:0031687=IEA, GO:0007268=IEA, GO:0014069=IEA, GO:0007205=IEA, GO:0007206=TAS, GO:0005737=IEA, GO:0000185=IEA, GO:0005887=TAS, GO:0043198=IEA, GO:0040013=IEA, GO:0002029=IEA, GO:0008066=TAS, GO:0006468=IEA, GO:0007626=IEA, GO:0016021=IEA, GO:0007612=IEA, GO:0048170=IEA} activation of MAPKKK activity, desensitization of G-protein coupled receptor protein signaling pathway, learning, locomotory behavior, negative regulation of locomotion, phospholipase C-activating G-protein coupled glutamate receptor signaling pathway, positive regulation of long-term neuronal synaptic plasticity, protein kinase C-activating G-protein coupled receptor signaling pathway, protein phosphorylation, regulation of transcription, DNA-dependent, synaptic transmission cytoplasm, dendritic shaft, integral to membrane, integral to plasma membrane, plasma membrane, postsynaptic density A2A adenosine receptor binding, G-protein coupled receptor activity, glutamate receptor activity Human UniProtKB-SubCell:SL-0039 GRM6 Reactome UniProtKB {GO:0009584=PMID:9215706, GO:0005886=Reactome:REACT_18380, GO:0060041=GO_REF:0000019, GO:0005887=PMID:9215706, GO:0004930=PMID:9215706, GO:0035841=GO_REF:0000019, GO:0001640=GO_REF:0000019, GO:0008066=PMID:9215706, GO:0007216=PMID:9215706, GO:0007268=GO_REF:0000019, GO:0007626=GO_REF:0000019, GO:0007601=GO_REF:0000037} O15303 Metabotropic glutamate receptor 6 protein 20090512 {GO:0009584=TAS, GO:0005886=TAS, GO:0060041=IEA, GO:0005887=TAS, GO:0004930=TAS, GO:0035841=IEA, GO:0001640=IEA, GO:0008066=TAS, GO:0007216=TAS, GO:0007268=IEA, GO:0007626=IEA, GO:0007601=IEA} G-protein coupled glutamate receptor signaling pathway, detection of visible light, locomotory behavior, retina development in camera-type eye, synaptic transmission, visual perception integral to plasma membrane, new growing cell tip, plasma membrane G-protein coupled receptor activity, adenylate cyclase inhibiting G-protein coupled glutamate receptor activity, glutamate receptor activity Human GRM7 Reactome UniProtKB {GO:0030424=GO_REF:0000024, GO:0007608=GO_REF:0000037, GO:0005886=Reactome:REACT_18380, GO:0007605=PMID:19047183, GO:0030818=PMID:9473604, GO:0014050=GO_REF:0000024, GO:0007268=PMID:9473604, GO:0007194=PMID:9473604, GO:0010855=PMID:9473604, GO:0030425=PMID:9630572, GO:0032279=GO_REF:0000024, GO:0043198=GO_REF:0000024, GO:0045211=GO_REF:0000024, GO:0030534=GO_REF:0000019, GO:0001662=PMID:17167337, GO:0001661=GO_REF:0000019, GO:0070905=PMID:9144652, GO:0005938=PMID:9630572, GO:0048786=GO_REF:0000024, GO:0005245=GO_REF:0000019, GO:0004930=GO_REF:0000038, GO:0005246=GO_REF:0000019, GO:0007614=GO_REF:0000019, GO:0001642=PMID:9473604, GO:0042734=GO_REF:0000019, GO:0007186=GO_REF:0000002, GO:0005887=PMID:9473604, GO:0008066=PMID:9473604, GO:0016595=PMID:9473604, GO:0016021=PMID:12746871} Q14831 Metabotropic glutamate receptor 7 protein 20090512 {GO:0030424=ISS, GO:0007608=IEA, GO:0005886=TAS, GO:0007605=IMP, GO:0030818=IDA, GO:0014050=ISS, GO:0007268=IDA, GO:0007194=IDA, GO:0010855=IDA, GO:0030425=IDA, GO:0032279=ISS, GO:0043198=ISS, GO:0045211=ISS, GO:0030534=IEA, GO:0001662=IMP, GO:0001661=IEA, GO:0070905=IDA, GO:0005938=IDA, GO:0048786=ISS, GO:0005245=IEA, GO:0004930=IEA, GO:0005246=IEA, GO:0007614=IEA, GO:0001642=IDA, GO:0042734=IEA, GO:0007186=IEA, GO:0005887=NAS, GO:0008066=IDA, GO:0016595=IDA, GO:0016021=IDA} G-protein coupled receptor signaling pathway, adult behavior, behavioral fear response, conditioned taste aversion, negative regulation of adenylate cyclase activity, negative regulation of cAMP biosynthetic process, negative regulation of glutamate secretion, sensory perception of smell, sensory perception of sound, short-term memory, synaptic transmission asymmetric synapse, axon, cell cortex, dendrite, dendritic shaft, integral to membrane, integral to plasma membrane, plasma membrane, postsynaptic membrane, presynaptic active zone, presynaptic membrane G-protein coupled receptor activity, adenylate cyclase inhibitor activity, calcium channel regulator activity, glutamate binding, glutamate receptor activity, group III metabotropic glutamate receptor activity, serine binding, voltage-gated calcium channel activity Human GRM8 Reactome UniProtKB {GO:0007608=GO_REF:0000037, GO:0005886=Reactome:REACT_18380, GO:0005887=PMID:9473604, GO:0004930=PMID:9473604, GO:0030818=PMID:11166323, GO:0008066=PMID:9473604, GO:0001642=GO_REF:0000019, GO:0016021=GO_REF:0000002, GO:0007194=PMID:9473604, GO:0007601=PMID:9473604} O00222 Metabotropic glutamate receptor 8 protein 20090512 {GO:0007608=IEA, GO:0005886=TAS, GO:0005887=TAS, GO:0004930=TAS, GO:0030818=IDA, GO:0008066=TAS, GO:0001642=IEA, GO:0016021=IEA, GO:0007194=TAS, GO:0007601=TAS} negative regulation of adenylate cyclase activity, negative regulation of cAMP biosynthetic process, sensory perception of smell, visual perception integral to membrane, integral to plasma membrane, plasma membrane G-protein coupled receptor activity, glutamate receptor activity, group III metabotropic glutamate receptor activity Human GRN HPA UniProtKB {GO:0005515=PMID:23088713, GO:0050679=GO_REF:0000019, GO:0005739=GO_REF:0000019, GO:0007165=PMID:1542665, GO:0008219=GO_REF:0000037, GO:0007566=GO_REF:0000019, GO:0001835=GO_REF:0000019, GO:0008083=PMID:1542665, GO:0005615=GO_REF:0000019, GO:0005125=GO_REF:0000037, GO:0043231=GO_REF:0000052} P28799 Granulins protein 20111111 {GO:0005515=IPI, GO:0050679=IEA, GO:0005739=IEA, GO:0007165=NAS, GO:0008219=IEA, GO:0007566=IEA, GO:0001835=IEA, GO:0008083=TAS, GO:0005615=IEA, GO:0005125=IEA, GO:0043231=IDA} blastocyst hatching, cell death, embryo implantation, positive regulation of epithelial cell proliferation, signal transduction extracellular space, intracellular membrane-bounded organelle, mitochondrion cytokine activity, growth factor activity, protein binding Human GRP Reactome UniProtKB {GO:0007165=PMID:3027901, GO:0007218=PMID:8756537, GO:0005102=PMID:3027901, GO:0005576=Reactome:REACT_22436, GO:0005184=PMID:8756537, GO:0005615=PMID:8756537} P07492 Gastrin-releasing peptide protein 20080826 {GO:0007165=NAS, GO:0007218=IDA, GO:0005102=NAS, GO:0005576=TAS, GO:0005184=IDA, GO:0005615=IDA} neuropeptide signaling pathway, signal transduction extracellular region, extracellular space neuropeptide hormone activity, receptor binding Human GRPEL1 HPA UniProtKB {GO:0005739=GO_REF:0000052, GO:0006457=GO_REF:0000002, GO:0005759=PMID:11311562, GO:0006626=Reactome:REACT_118595, GO:0051087=GO_REF:0000002, GO:0051082=PMID:11311562, GO:0030150=GO_REF:0000029, GO:0044267=Reactome:REACT_17015, GO:0042803=GO_REF:0000002, GO:0000774=GO_REF:0000002} Q9HAV7 GrpE protein homolog 1, mitochondrial protein 20110516 {GO:0005739=IDA, GO:0006457=IEA, GO:0005759=IDA, GO:0006626=TAS, GO:0051087=IEA, GO:0051082=IDA, GO:0030150=NAS, GO:0044267=TAS, GO:0042803=IEA, GO:0000774=IEA} cellular protein metabolic process, protein folding, protein import into mitochondrial matrix, protein targeting to mitochondrion mitochondrial matrix, mitochondrion adenyl-nucleotide exchange factor activity, chaperone binding, protein homodimerization activity, unfolded protein binding Human GRPEL2 HPA UniProtKB {GO:0005739=GO_REF:0000052, GO:0005737=GO_REF:0000052, GO:0006457=GO_REF:0000002, GO:0005759=GO_REF:0000039, GO:0006626=Reactome:REACT_118595, GO:0005743=GO_REF:0000019, GO:0051087=GO_REF:0000002, GO:0051082=GO_REF:0000019, GO:0044267=Reactome:REACT_17015, GO:0042803=GO_REF:0000002, GO:0000774=GO_REF:0000002} Q8TAA5 GrpE protein homolog 2, mitochondrial protein 20090616 {GO:0005739=IDA, GO:0005737=IDA, GO:0006457=IEA, GO:0005759=IEA, GO:0006626=TAS, GO:0005743=IEA, GO:0051087=IEA, GO:0051082=IEA, GO:0044267=TAS, GO:0042803=IEA, GO:0000774=IEA} cellular protein metabolic process, protein folding, protein targeting to mitochondrion cytoplasm, mitochondrial inner membrane, mitochondrial matrix, mitochondrion adenyl-nucleotide exchange factor activity, chaperone binding, protein homodimerization activity, unfolded protein binding Human GRPR Reactome UniProtKB {GO:0004946=GO_REF:0000002, GO:0005886=Reactome:REACT_22436, GO:0007186=PMID:1655761, GO:0005887=PMID:8391296, GO:0008283=PMID:1655761, GO:0042127=GO_REF:0000019, GO:0008528=PMID:7838118} P30550 Gastrin-releasing peptide receptor protein 20080826 {GO:0004946=IEA, GO:0005886=TAS, GO:0007186=TAS, GO:0005887=TAS, GO:0008283=TAS, GO:0042127=IEA, GO:0008528=TAS} G-protein coupled receptor signaling pathway, cell proliferation, regulation of cell proliferation integral to plasma membrane, plasma membrane G-protein coupled peptide receptor activity, bombesin receptor activity Human GRSF1 HPA UniProtKB {GO:0005739=GO_REF:0000052, GO:0006378=PMID:8036161, GO:0005737=PMID:8036161, GO:0016331=GO_REF:0000019, GO:0000166=GO_REF:0000002, GO:0003723=PMID:8036161, GO:0003729=PMID:8036161, GO:0009952=GO_REF:0000019, GO:0003676=GO_REF:0000002} Q12849 G-rich sequence factor 1 protein 20110516 {GO:0005739=IDA, GO:0006378=TAS, GO:0005737=TAS, GO:0016331=IEA, GO:0000166=IEA, GO:0003723=TAS, GO:0003729=TAS, GO:0009952=IEA, GO:0003676=IEA} anterior/posterior pattern specification, mRNA polyadenylation, morphogenesis of embryonic epithelium cytoplasm, mitochondrion RNA binding, mRNA binding, nucleic acid binding, nucleotide binding Human GRTP1 InterPro UniProtKB {GO:0005622=GO_REF:0000002, GO:0005097=GO_REF:0000002} Q5TC63 Growth hormone-regulated TBC protein 1 protein 20130413 {GO:0005622=IEA, GO:0005097=IEA} intracellular Rab GTPase activator activity Human InterPro:IPR000195 GRWD1 HPA UniProtKB {GO:0005737=GO_REF:0000052, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052} Q9BQ67 Glutamate-rich WD repeat-containing protein 1 protein 20111111 {GO:0005737=IDA, GO:0005730