ID entrez description locus hprd hgnc mim refpro refdna ensembl type dominant recessive duplicability origin degree mirna function expression chromosome tstart tend type_of_screening cancer_type AACS 65985 acetoacetyl-CoA synthetase 12q24.31 12391 21298 614364 NP_076417 NM_023928 ENSP00000324842 candidate 0 0 0 Last Universal Common Ancestor 1 1 Cellular metabolism 73 chr12 125550131 125626772 WGS liver ABCA1 19 ATP-binding cassette, sub-family A (ABC1), member 1 9q31.1 2501 29 600046 NP_005493 NM_005502 ENSP00000363868 candidate 0 0 0 Last Universal Common Ancestor 58 6 Cellular metabolism,Cellular processes,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction 91 chr9 107546599 107665960 WES colorectal ABCA3 21 ATP-binding cassette, sub-family A (ABC1), member 3 16p13.3 3369 33 601615 NP_001080 NM_001089 ENSP00000301732 candidate 0 0 0 Last Universal Common Ancestor 2 1 -1 49 chr16 2326678 2376467 WES breast ABCA7 10347 ATP-binding cassette, sub-family A (ABC1), member 7 19p13.3 9255 37 605414 NP_061985 "NM_019112;NM_033308" ENSP00000263094 candidate 0 0 0 Last Universal Common Ancestor 5 1 Cellular processes 69 chr19 1041361 1065421 WES pancreas ABCB11 8647 ATP-binding cassette, sub-family B (MDR/TAP), member 11 2q24 4436 42 603201 NP_003733 NM_003742 ENSP00000263817 candidate 0 0 0 Last Universal Common Ancestor 4 1 -1 21 chr2 169780135 169874635 WES,WGS colorectal,breast ABCB5 340273 ATP-binding cassette, sub-family B (MDR/TAP), member 5 7p21.1 - 46 611785 "NP_001157465;NP_001157413;NP_848654;NP_001157414" "NM_001163993;NM_001163941;NM_178559;NM_001163942" "ENSP00000384881;ENSP00000406730;ENSP00000383899" candidate 0 0 0 Last Universal Common Ancestor 2 2 -1 -1 chr7 20662909 20795244 WGS chronic lymphocytic leukemia ABCB8 11194 ATP-binding cassette, sub-family B (MDR/TAP), member 8 7q36 10400 49 605464 NP_009119 NM_007188 ENSP00000351717 candidate 0 0 0 Last Universal Common Ancestor 7 0 -1 0 chr7 150725603 150742433 WES breast ABCC5 10057 ATP-binding cassette, sub-family C (CFTR/MRP), member 5 3q27 6898 56 605251 "NP_005679;NP_001018881" "NM_005688;NM_001023587" "ENSP00000371934;ENSP00000333926" candidate 0 0 0 Last Universal Common Ancestor 5 1 -1 97 chr3 183639091 183732180 WES pancreas ABCC9 10060 ATP-binding cassette, sub-family C (CFTR/MRP), member 9 12p12.1 3258 60 601439 "NP_064693;NP_005682" "NM_020298;NM_020297;NM_005691" "ENSP00000261201;ENSP00000261200" candidate 0 0 0 Last Universal Common Ancestor 200 1 Cell response to stimuli,Cellular processes 49 chr12 21958111 22089608 WES endometrium,gastric ABCE1 6059 ATP-binding cassette, sub-family E (OABP), member 1 4q31 3132 69 601213 "NP_001035809;NP_002931" "NM_001040876;NM_002940" ENSP00000296577 candidate 0 0 1 Last Universal Common Ancestor 13 3 Cell response to stimuli,Cellular metabolism,DNA/RNA metabolism and transcription 95 chr4 146025565 146048722 WGS prostate ABCF3 55324 ATP-binding cassette, sub-family F (GCN20), member 3 3q27.1 12404 72 - NP_060828 NM_018358 ENSP00000411471 candidate 0 0 0 Last Universal Common Ancestor 32 0 -1 93 chr3 183903996 183911483 WGS lung ABCG5 64240 ATP-binding cassette, sub-family G (WHITE), member 5 2p21 5678 13886 605459 NP_071881 NM_022436 ENSP00000260645 candidate 0 0 0 Last Universal Common Ancestor 4 0 Cell response to stimuli,Cellular processes,Multicellular activities 10 chr2 44040258 44065818 WGS lymphoma ABCG8 64241 ATP-binding cassette, sub-family G (WHITE), member 8 2p21 5679 13887 605460 NP_071882 NM_022437 ENSP00000272286 candidate 0 0 0 Last Universal Common Ancestor 9 4 -1 -1 chr2 44066193 44105049 WES melanoma ABI1 10006 abl-interactor 1 10p11.2 4336 11320 603050 "NP_001171595;NP_005461;NP_001171592;NP_001171593;NP_001171587;NP_001171590;NP_001012770;NP_001171594;NP_001171596;NP_001012769;NP_001012768;NP_001171591" "NM_001178124;NM_005470;NM_001178121;NM_001178122;NM_001178116;NM_001178119;NM_001012752;NM_001178123;NM_001178125;NM_001012751;NM_001012750;NM_001178120" "ENSP00000365308;ENSP00000365309;ENSP00000279599;ENSP00000352114;ENSP00000365340;ENSP00000365336;ENSP00000365307;ENSP00000439646;ENSP00000440101;ENSP00000365312" known 1 0 0 Eukaryotes 71 0 Cell cycle,Cellular metabolism,Cellular processes,Regulation of intracellular processes and metabolism,Signal transduction 89 chr10 27037502 27149792 CGC leukemia ABI3 51225 ABI family, member 3 17q21.3 5900 29859 606363 "NP_057512;NP_001128658" "NM_016428;NM_001135186" "ENSP00000406651;ENSP00000225941" candidate 0 0 0 Eukaryotes 31 0 Cell motility and interactions,Cellular metabolism,Cellular processes -1 chr17 47288087 47300074 WES head and neck squamous cell carcinoma ABI3BP 25890 ABI family, member 3 (NESH) binding protein 3q12 9380 17265 606279 NP_056244 NM_015429 ENSP00000284322 candidate 0 0 0 Metazoans 5 0 -1 10 chr3 100469342 100712249 WGS chronic lymphocytic leukemia ABL1 25 c-abl oncogene 1, non-receptor tyrosine kinase 9q34.1 1809 76 189980 "NP_005148;NP_009297" "NM_005157;NM_007313" ENSP00000323315 known 1 0 0 Last Universal Common Ancestor 365 3 Cell cycle,Cellular metabolism,Cellular processes,DNA/RNA metabolism and transcription,Development,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction 100 chr9 133589707 133761067 CGC leukemia ABL2 27 v-abl Abelson murine leukemia viral oncogene homolog 2 1q25.2 1259 77 164690 "NP_001129472;NP_005149;NP_001161708;NP_001161711;NP_009298;NP_001161709;NP_001161710;NP_001129473" "NM_001136000;NM_005158;NM_001168236;NM_001168239;NM_007314;NM_001168237;NM_001168238;NM_001136001" "ENSP00000375897;ENSP00000386152;ENSP00000427562" known 1 0 0 Last Universal Common Ancestor 40 5 Cellular metabolism,Cellular processes,Regulation of intracellular processes and metabolism,Signal transduction 57 chr1 179076856 179198532 CGC leukemia ABLIM2 84448 actin binding LIM protein family, member 2 4p16.1 - 19195 612544 "NP_001123556;NP_001123560;NP_001123558;NP_001123557;NP_115808;NP_001123559;NP_001123555" "NM_001130084;NM_001130088;NM_001130086;NM_001130085;NM_032432;NM_001130087;NM_001130083" "ENSP00000441255;ENSP00000354887;ENSP00000389410" candidate 0 0 0 Eukaryotes 3 0 Cellular processes -1 chr4 7968720 8108365 WES pancreas ABP1 26 amiloride binding protein 1 (amine oxidase (copper-containing)) 7q34-q36 88 80 104610 NP_001082 NM_001091 ENSP00000354193 candidate 0 0 0 Last Universal Common Ancestor 3 0 -1 53 chr7 150553559 150558294 WES breast ACADM 34 acyl-CoA dehydrogenase, C-4 to C-12 straight chain 1p31 8447 89 607008 "NP_000007;NP_001120800" "NM_000016;NR_022013;NM_001127328" ENSP00000359878 candidate 0 0 0 Last Universal Common Ancestor 11 4 Cellular metabolism,Cellular processes 93 chr1 76194074 76228445 WES breast ACAN 176 aggrecan 15q26.1 1123 319 155760 "NP_001126;NP_037359" "NM_001135;NM_013227" "ENSP00000341615;ENSP00000387356" candidate 0 0 0 Last Universal Common Ancestor 18 0 Cell motility and interactions,Cellular metabolism,Development 62 chr15 89379438 89417709 WES colorectal ACAP1 9744 ArfGAP with coiled-coil, ankyrin repeat and PH domains 1 17p13.1 8474 16467 607763 NP_055531 NM_014716 ENSP00000158762 candidate 0 0 0 Eukaryotes 11 0 Cellular processes,Regulation of intracellular processes and metabolism,Signal transduction 35 chr17 7240054 7254711 WES breast ACE 1636 angiotensin I converting enzyme (peptidyl-dipeptidase A) 1 17q23.3 108 2707 106180 "NP_000780;NP_001171528;NP_690043" "NM_000789;NM_152831;NM_001178057;NM_152830" ENSP00000290866 candidate 0 0 0 Last Universal Common Ancestor 4 1 Cell cycle,Cell motility and interactions,Cellular metabolism,Cellular processes,Development,Multicellular activities,Regulation of intracellular processes and metabolism 23 chr17 61554456 61574724 WES lymphoma ACER2 340485 alkaline ceramidase 2 9p22.1 16512 23675 613492 NP_001010887 NM_001010887 - candidate 0 0 1 Eukaryotes 0 0 Cellular metabolism -1 chr9 19409083 19450631 WGS chronic lymphocytic leukemia ACIN1 22985 apoptotic chromatin condensation inducer 1 14q11.2 5191 17066 604562 "NP_001158287;NP_001158286;NP_001158288;NP_001158289;NP_055792" "NM_001164815;NM_001164814;NM_001164816;NM_001164817;NM_014977" "ENSP00000451328;ENSP00000405677;ENSP00000345541;ENSP00000350073;ENSP00000262710" candidate 0 0 0 Eukaryotes 14 3 Cell cycle,Cellular processes,DNA/RNA metabolism and transcription,Development,Multicellular activities,Regulation of intracellular processes and metabolism,Signal transduction 62 chr14 23528360 23564495 WGS prostate ACSBG2 81616 acyl-CoA synthetase bubblegum family member 2 19p13.3 9824 24174 614363 NP_112186 NM_030924 ENSP00000252669 candidate 0 0 0 Last Universal Common Ancestor 1 0 Cellular metabolism,Development,Multicellular activities 43 chr19 6141555 6190665 WGS prostate ACSL3 2181 acyl-CoA synthetase long-chain family member 3 2q34-q35 3845 3570 602371 "NP_976251;NP_004448" "NM_203372;NM_004457" - known 1 0 0 Last Universal Common Ancestor 13 4 Cellular metabolism 94 chr2 223773491 223806369 CGC prostate ACSL5 51703 acyl-CoA synthetase long-chain family member 5 10q25.1-q25.2 16139 16526 605677 "NP_976313;NP_057318;NP_976314" "NM_203379;NM_016234;NM_203380" "ENSP00000348429;ENSP00000346680;ENSP00000376796" candidate 0 0 0 Last Universal Common Ancestor 2 6 Cellular metabolism 83 chr10 114136068 114187113 WES colorectal ACSL6 23305 acyl-CoA synthetase long-chain family member 6 5q31 9190 16496 604443 "NP_001192177;NP_001192180;NP_001192179;NP_056071;NP_001192176;NP_001009185" "NM_001205248;NM_001205251;NM_001205250;NM_015256;NM_001205247;NM_001009185" ENSP00000368566 known 1 0 0 Last Universal Common Ancestor 0 1 Cell cycle,Cellular metabolism,Development 93 chr5 131289930 131347246 CGC leukemia ACSM1 116285 acyl-CoA synthetase medium-chain family member 1 16p12.3 12551 18049 614357 NP_443188 NM_052956 ENSP00000301956 candidate 0 0 0 Last Universal Common Ancestor 0 1 Cellular metabolism 2 chr16 20634811 20702510 WES pancreas ACTB 60 actin, beta 7p22 32 132 102630 NP_001092 NM_001101 ENSP00000349960 candidate 0 0 39 Last Universal Common Ancestor 146 2 Cell response to stimuli 109 chr7 5567382 5569288 WES lymphoma ACVR1B 91 activin A receptor, type IB 12q13 3193 172 601300 "NP_064733;NP_064732;NP_004293" "NM_020328;NM_020327;NM_004302" ENSP00000257963 candidate 0 0 0 Last Universal Common Ancestor 32 6 Cell cycle,Cellular metabolism,Cellular processes,DNA/RNA metabolism and transcription,Development,Multicellular activities,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction 100 chr12 52345528 52387891 HTMS,WES breast,lung,ovarian,pancreas,prostate,colorectal (non-hypermutated) ACVR2A 92 activin A receptor, type IIA 2q22.3 25 173 102581 NP_001607 NM_001616 ENSP00000241416 candidate 0 0 0 Last Universal Common Ancestor 23 5 Cellular metabolism,Cellular processes,Development,Multicellular activities,Regulation of intracellular processes and metabolism,Signal transduction 95 chr2 148602722 148684840 WES colorectal (hypermutated),gastric ADAM10 102 ADAM metallopeptidase domain 10 15q2|15q22 3723 188 602192 NP_001101 NM_001110 - candidate 0 0 0 Eukaryotes 4 2 Cell motility and interactions,Cellular metabolism,Cellular processes,Development,Regulation of intracellular processes and metabolism,Signal transduction 65 chr15 58889749 59041733 WES lymphoma ADAM12 8038 ADAM metallopeptidase domain 12 10q26.3 4092 190 602714 "NP_003465;NP_067673" "NM_003474;NM_021641" ENSP00000357665 candidate 0 0 0 Last Universal Common Ancestor 32 4 Cell cycle,Cellular metabolism,Cellular processes,Development 60 chr10 127705851 128076714 WES breast ADAM18 8749 ADAM metallopeptidase domain 18 8p11.22 7469 196 - "NP_001177885;NP_055052" "NM_001190956;NM_014237" "ENSP00000429908;ENSP00000265707" candidate 0 0 0 Eukaryotes 39 1 Cellular metabolism,Development,Multicellular activities 27 chr8 39442142 39581427 WGS prostate ADAM19 8728 ADAM metallopeptidase domain 19 5q33.3 4704 197 603640 NP_150377 "NM_023038;NM_033274" ENSP00000257527 candidate 0 0 0 Last Universal Common Ancestor 15 0 Cellular metabolism 77 chr5 156907960 157002704 WES colorectal ADAM2 2515 ADAM metallopeptidase domain 2 8p11.2 3322 198 601533 NP_001455 NM_001464 ENSP00000265708 candidate 0 0 0 Eukaryotes 4 1 Cellular metabolism,Cellular processes,Development 11 chr8 39603990 39695704 WES chronic lymphocytic leukemia ADAM22 53616 ADAM metallopeptidase domain 22 7q21 4751 201 603709 "NP_057435;NP_068369;NP_068368;NP_004185;NP_068367" "NM_016351;NM_021723;NM_021722;NM_004194;NM_021721" "ENSP00000381260;ENSP00000381262;ENSP00000381267" candidate 0 0 0 Eukaryotes 9 0 Cell motility and interactions,Cellular metabolism,Development,Regulation of intracellular processes and metabolism 52 chr7 87563781 87822554 WGS liver ADAM29 11086 ADAM metallopeptidase domain 29 4q34 5306 207 604778 "NP_001124176;NP_055084;NP_001124175;NP_001124177" "NM_001130704;NM_014269;NM_001130703;NM_001130705" "ENSP00000414544;ENSP00000384229;ENSP00000423517;ENSP00000352177" candidate 0 0 0 Eukaryotes 238 1 Cellular metabolism,Development,Multicellular activities 12 chr4 175896677 175899136 WES,WGS colorectal,melanoma ADAM7 8756 ADAM metallopeptidase domain 7 8p21.2 7391 214 607310 NP_003808 NM_003817 ENSP00000175238 candidate 0 0 0 Eukaryotes 3 0 Cellular metabolism 21 chr8 24298622 24365046 WES melanoma ADAM8 101 ADAM metallopeptidase domain 8 10q26.3 3777 215 602267 "NP_001100;NP_001157962;NP_001157961" "NM_001109;NM_001164490;NM_001164489" "ENSP00000453302;ENSP00000453855;ENSP00000453043" candidate 0 0 0 Eukaryotes 2 1 Cellular metabolism 23 chr10 135076663 135089092 WGS glioblastoma ADAMTS1 9510 ADAM metallopeptidase with thrombospondin type 1 motif, 1 21q21.2 5530 217 605174 NP_008919 NM_006988 ENSP00000284984 candidate 0 0 0 Eukaryotes 24 5 Cell cycle,Cellular metabolism,Regulation of intracellular processes and metabolism,Signal transduction 81 chr21 28209901 28217273 WGS lung ADAMTS10 81794 ADAM metallopeptidase with thrombospondin type 1 motif, 10 19p13.2 7470 13201 608990 NP_112219 NM_030957 ENSP00000471851 candidate 0 0 0 Eukaryotes 10 0 Cellular metabolism,Signal transduction -1 chr19 8645780 8670595 WGS lymphoma ADAMTS12 81792 ADAM metallopeptidase with thrombospondin type 1 motif, 12 5q35 5862 14605 606184 NP_112217 NM_030955 ENSP00000344847 candidate 0 0 0 Last Universal Common Ancestor 0 2 Cellular metabolism 71 chr5 33527296 33891961 WES head and neck squamous cell carcinoma ADAMTS13 11093 ADAM metallopeptidase with thrombospondin type 1 motif, 13 9q34 4994 1366 604134 "NP_620595;NP_620596;NP_620594" "NM_139028;NM_139026;NM_139027;NR_024514;NM_139025" "ENSP00000360997;ENSP00000348997;ENSP00000347927" candidate 0 0 0 Eukaryotes 10 0 Cell motility and interactions,Cellular metabolism,Cellular processes,Multicellular activities,Signal transduction 21 chr9 136287564 136324299 WGS melanoma ADAMTS18 170692 ADAM metallopeptidase with thrombospondin type 1 motif, 18 16q23 6333 17110 607512 NP_955387 "NM_139054;NM_199355" ENSP00000282849 candidate 0 0 0 Last Universal Common Ancestor 0 0 Cellular metabolism -1 chr16 77317856 77468592 WES colorectal ADAMTS20 80070 ADAM metallopeptidase with thrombospondin type 1 motif, 20 12q12 - 17178 611681 NP_079279 "NM_025003;NM_175851" ENSP00000374071 candidate 0 0 0 Last Universal Common Ancestor 1 0 Cellular metabolism 22 chr12 43748015 43945724 WES colorectal,pancreas ADAMTSL3 57188 ADAMTS-like 3 15q25.2 12426 14633 609199 NP_997400 NM_207517 ENSP00000286744 candidate 0 0 0 Eukaryotes 0 0 -1 65 chr15 84324514 84706555 WES colorectal,lymphoma ADARB2 105 adenosine deaminase, RNA-specific, B2 10p15.3 9070 227 602065 NP_061172 NM_018702 - candidate 0 0 0 Eukaryotes 1 0 DNA/RNA metabolism and transcription,Regulation of transcription 27 chr10 1229136 1779344 WES colorectal ADCY1 107 adenylate cyclase 1 (brain) 7p13-p12 53 232 103072 NP_066939 NM_021116 ENSP00000297323 candidate 0 0 0 Last Universal Common Ancestor 2 0 Cellular metabolism,DNA/RNA metabolism and transcription,Signal transduction 63 chr7 45614143 45753591 WES lung ADCY2 108 adenylate cyclase 2 (brain) 5p15.3 52 233 103071 NP_065433 NM_020546 ENSP00000342952 candidate 0 0 0 Last Universal Common Ancestor 3 0 Cellular metabolism,DNA/RNA metabolism and transcription,Signal transduction 73 chr5 7396410 7826981 WGS lung ADCY3 109 adenylate cyclase 3 2p23.3 2620 234 600291 NP_004027 NM_004036 ENSP00000260600 candidate 0 0 0 Last Universal Common Ancestor 3 3 Cell cycle,Cell response to stimuli,Cellular metabolism,DNA/RNA metabolism and transcription,Signal transduction 97 chr2 25042804 25141856 WGS breast ADCY8 114 adenylate cyclase 8 (brain) 8q24 51 239 103070 NP_001106 NM_001115 ENSP00000367161 candidate 0 0 0 Last Universal Common Ancestor 4 0 Cellular metabolism,DNA/RNA metabolism and transcription,Signal transduction 9 chr8 131792639 132052579 WES,WGS head and neck squamous cell carcinoma,lung ADRA1A 148 adrenergic, alpha-1A-, receptor 8p21.2 81 277 104221 "NP_000671;NP_150647;NP_150646;NP_150645" "NM_000680;NM_033304;NM_033303;NM_033302" "ENSP00000276393;ENSP00000369956;ENSP00000369960;ENSP00000346557" candidate 0 0 0 Metazoans 12 0 Cell cycle,Multicellular activities,Regulation of intracellular processes and metabolism,Signal transduction 60 chr8 26627783 26722486 WGS melanoma ADRA2C 152 adrenergic, alpha-2C-, receptor 4p16 85 283 104250 NP_000674 NM_000683 ENSP00000386069 candidate 0 0 0 Metazoans 5 0 Cellular metabolism,Cellular processes,Regulation of intracellular processes and metabolism,Signal transduction 14 chr4 3768334 3769719 WGS melanoma AFF1 4299 AF4/FMR2 family, member 1 4q21 8871 7135 159557 "NP_001160165;NP_005926" "NM_001166693;NM_005935" "ENSP00000378578;ENSP00000305689" known 1 0 0 Eukaryotes 30 1 -1 108 chr4 87967313 88056850 CGC leukemia AFF2 2334 AF4/FMR2 family, member 2 Xq28 2397 3776 300806 "NP_001162594;NP_001162595;NP_001164099;NP_002016;NP_001162596;NP_001162593" "NM_001169123;NM_001169124;NM_001170628;NM_002025;NM_001169125;NM_001169122" "ENSP00000359486;ENSP00000286437;ENSP00000359489" candidate 0 0 0 Metazoans 4 0 Development 83 chrX 147582618 148072859 WES breast AFF3 3899 AF4/FMR2 family, member 3 2q11.2-q12 3272 6473 601464 "NP_001020279;NP_002276" "NM_001025108;NM_002285" "ENSP00000348793;ENSP00000317421" known 1 0 0 Metazoans 1 0 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription 4 chr2 100167939 100720916 CGC leukemia AFF4 27125 AF4/FMR2 family, member 4 5q31 9187 17869 604417 NP_055238 NM_014423 ENSP00000265343 known 1 0 0 Metazoans 27 8 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription 25 chr5 132216754 132272881 CGC leukemia AGAP2 116986 ArfGAP with GTPase domain, ankyrin repeat and PH domain 2 12q14.1 5687 16921 605476 "NP_001116244;NP_055585" "NM_001122772;NM_014770" ENSP00000257897 candidate 0 0 0 Eukaryotes 10 0 Cellular processes,Regulation of intracellular processes and metabolism,Signal transduction 40 chr12 58120338 58132029 WES breast AGFG1 3267 ArfGAP with FG repeats 1 2q36.3 2918 5175 600862 "NP_001128661;NP_004495;NP_001128659;NP_001128660" "NM_001135189;NM_004504;NM_001135187;NM_001135188" - candidate 0 0 0 Eukaryotes 14 4 Cellular processes,DNA/RNA metabolism and transcription,Development,Multicellular activities,Regulation of intracellular processes and metabolism,Signal transduction 103 chr2 228337138 228419208 WGS melanoma AGMO 392636 alkylglycerol monooxygenase 7p21.2 13362 33784 613738 NP_001004320 NM_001004320 ENSP00000341662 candidate 0 0 0 Last Universal Common Ancestor 0 0 -1 -1 chr7 15240913 15601470 WGS liver AGXT2L2 85007 alanine-glyoxylate aminotransferase 2-like 2 5q35.3 18482 28249 - NP_699204 "NM_153373;NM_032921" ENSP00000310978 candidate 0 0 0 Last Universal Common Ancestor 1 0 -1 -1 chr5 177638925 177659551 WGS chronic lymphocytic leukemia AHNAK 79026 AHNAK nucleoprotein 11q12.2 14684 347 103390 "NP_001611;NP_076965" "NM_001620;NM_024060" "ENSP00000367263;ENSP00000257247" candidate 0 0 0 Last Universal Common Ancestor 29 2 Development 97 chr11 62284219 62303570 WES kidney AHNAK2 113146 AHNAK nucleoprotein 2 14q32.33 - 20125 608570 NP_612429 NM_138420 ENSP00000353114 candidate 0 0 0 Last Universal Common Ancestor 3 7 Development 49 chr14 105404403 105444574 WGS melanoma AIM1 202 absent in melanoma 1 6q21 18576 356 601797 NP_001615 NM_001624 ENSP00000358062 candidate 0 0 0 Last Universal Common Ancestor 2 5 -1 94 chr6 106960217 107016438 WES breast AK2 204 adenylate kinase 2 1p34 47 362 103020 "NP_001616;NP_037543;NP_001186128" "NR_037592;NM_001625;NM_013411;NR_037591;NM_001199199" ENSP00000362548 candidate 0 0 1 Last Universal Common Ancestor 25 7 -1 107 chr1 33478785 33502429 WGS chronic lymphocytic leukemia AKAP11 11215 A kinase (PRKA) anchor protein 11 13q14.11 5261 369 604696 NP_057332 "NM_016248;NM_144490" ENSP00000025301 candidate 0 0 0 Vertebrates 25 13 Signal transduction 103 chr13 42860485 42893361 WES pancreas AKAP12 9590 A kinase (PRKA) anchor protein 12 6q24-q25 5263 370 604698 "NP_653080;NP_005091" "NM_144497;NM_005100" ENSP00000384537 candidate 0 0 0 Last Universal Common Ancestor 10 4 Cellular processes,Signal transduction 92 chr6 151561698 151674872 WES colorectal AKAP13 11214 A kinase (PRKA) anchor protein 13 15q24-q25 5253 371 604686 "NP_658913;NP_009131;NP_006729" "NM_144767;NM_007200;NM_006738" ENSP00000378026 candidate 0 0 0 Eukaryotes 8 1 Signal transduction 102 chr15 86064659 86287905 WES,WGS kidney,pancreas,liver AKAP6 9472 A kinase (PRKA) anchor protein 6 14q12 5257 376 604691 NP_004265 NM_004274 ENSP00000280979 candidate 0 0 0 Eukaryotes 17 0 Cellular processes 86 chr14 32902700 33293976 WES chronic lymphocytic leukemia,colorectal AKAP8 10270 A kinase (PRKA) anchor protein 8 19p13.1 5258 378 604692 NP_005849 NM_005858 ENSP00000269701 candidate 0 0 0 Vertebrates 15 4 Cell cycle,DNA/RNA metabolism and transcription,Signal transduction 68 chr19 15465729 15487826 WES lymphoma AKAP9 10142 A kinase (PRKA) anchor protein (yotiao) 9 7q21-q22 4921 379 604001 "NP_005742;NP_671714" "NM_147171;NM_005751;NM_147185;NM_147166" ENSP00000348573 known 1 0 0 Last Universal Common Ancestor 39 2 Multicellular activities,Signal transduction 77 chr7 91570414 91737949 CGC,HTMS thyroid,breast,lung,ovarian,pancreas,prostate AKR1B10 57016 aldo-keto reductase family 1, member B10 (aldose reductase) 7q33 5271 382 604707 NP_064695 NM_020299 ENSP00000352584 candidate 0 0 2 Last Universal Common Ancestor 49 5 Cellular metabolism 40 chr7 134212664 134223770 WES melanoma AKT1 207 v-akt murine thymoma viral oncogene homolog 1 14q32.32|14q32.32 1261 391 164730 "NP_001014432;NP_001014431;NP_005154" "NM_001014432;NM_001014431;NM_005163" "ENSP00000384293;ENSP00000270202;ENSP00000450688" known 1 0 2 Last Universal Common Ancestor 65 11 Cell cycle,Cell response to stimuli,Cellular metabolism,Cellular processes,Development,Immune system response,Multicellular activities,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction 90 chr14 105236681 105258980 CGC,HTMS,WES breast,colorectal,lung,ovarian,pancreas,prostate AKT2 208 v-akt murine thymoma viral oncogene homolog 2 19q13.1-q13.2 1262 392 164731 "NP_001229956;NP_001229957;NP_001617" "NM_001243027;NM_001243028;NM_001626" ENSP00000375892 known 1 0 1 Last Universal Common Ancestor 20 5 Cellular metabolism,Cellular processes 21 chr19 40739782 40771174 CGC,WES,Amplified ovarian,pancreas,breast AKT3 10000 v-akt murine thymoma viral oncogene homolog 3 (protein kinase B, gamma) 1q44 6441 393 611223 "NP_001193658;NP_005456;NP_859029" "NM_001206729;NM_005465;NM_181690" "ENSP00000355498;ENSP00000336943" known 0 0 1 Last Universal Common Ancestor 5 8 Cellular metabolism,Cellular processes,Signal transduction 97 chr1 243668554 244006472 CGC,Amplified AKTIP 64400 AKT interacting protein 16q12.2 7467 16710 608483 "NP_071921;NP_001012398" "NM_022476;NM_001012398" ENSP00000378152 candidate 0 0 1 Eukaryotes 57 0 Cellular metabolism,Cellular processes,Regulation of intracellular processes and metabolism 57 chr16 53526327 53534171 WGS prostate ALB 213 albumin 4q13.3 62 399 103600 NP_000468 NM_000477 ENSP00000295897 candidate 0 0 0 Vertebrates 168 0 Cell cycle,Cell motility and interactions,Cell response to stimuli,Cellular processes,Development,Other,Regulation of intracellular processes and metabolism 35 chr4 74270045 74286012 WGS liver ALDH2 217 aldehyde dehydrogenase 2 family (mitochondrial) 12q24.2 3 404 100650 "NP_001191818;NP_000681" "NM_001204889;NM_000690" "ENSP00000261733;ENSP00000403349" known 1 0 1 Last Universal Common Ancestor 13 5 Signal transduction 102 chr12 112204787 112241786 CGC leiomyoma ALK 238 anaplastic lymphoma receptor tyrosine kinase 2p23 104 427 105590 NP_004295 NM_004304 ENSP00000373700 known 1 0 0 Last Universal Common Ancestor 58 1 Cellular metabolism,Cellular processes,Development,Signal transduction 37 chr2 29416093 30143525 CGC,WES lung,lymphoma,neuroblastoma,colorectal ALLC 55821 allantoicase 2q35 10642 17377 612396 NP_060906 "NM_018436;NM_199232" ENSP00000252505 candidate 0 0 0 Last Universal Common Ancestor 35 0 -1 17 chr2 3721665 3750150 WES head and neck squamous cell carcinoma ALMS1 7840 Alstrom syndrome 1 2p13 6023 428 606844 NP_055935 NM_015120 ENSP00000264448 candidate 0 0 0 Metazoans 3 3 Cell response to stimuli 102 chr2 73613033 73836736 WES pancreas ALOX12 239 arachidonate 12-lipoxygenase 17p13.1 1066 429 152391 NP_000688 NM_000697 ENSP00000251535 candidate 0 0 0 Last Universal Common Ancestor 13 0 Cell cycle,Cell motility and interactions,Cellular metabolism,Cellular processes,Development,Regulation of intracellular processes and metabolism 18 chr17 6899437 6913739 WES,WGS myeloma ALOX15B 247 arachidonate 15-lipoxygenase, type B 17p13.1 4739 434 603697 "NP_001034219;NP_001132;NP_001034220" "NM_001039130;NM_001141;NM_001039131" "ENSP00000369520;ENSP00000369530" candidate 0 0 0 Last Universal Common Ancestor 1 0 Cell cycle,Cell motility and interactions,Cellular metabolism,Development,Regulation of intracellular processes and metabolism 52 chr17 7942474 7951880 WGS prostate ALS2 57679 amyotrophic lateral sclerosis 2 (juvenile) 2q33.1 5893 443 606352 "NP_065970;NP_001129217" "NM_020919;NM_001135745" "ENSP00000429223;ENSP00000264276" candidate 0 0 0 Last Universal Common Ancestor 6 0 Cell cycle,Cell response to stimuli,Cellular processes,Development,Multicellular activities,Regulation of intracellular processes and metabolism,Signal transduction -1 chr2 202568845 202632108 WGS melanoma ALS2CL 259173 ALS2 C-terminal like 3p21.31 10643 20605 612402 "NP_001177636;NP_667340;NP_877576" "NR_033815;NM_001190707;NM_147129;NM_182775" ENSP00000313670 candidate 0 0 0 Last Universal Common Ancestor 21 0 Cellular processes 64 chr3 46712477 46730930 WES chronic lymphocytic leukemia AMFR 267 autocrine motility factor receptor 16q21 9130 463 603243 NP_001135 "NM_138958;NM_001144" ENSP00000290649 candidate 0 0 0 Eukaryotes 86 0 Cell response to stimuli,Cellular metabolism,Cellular processes,Signal transduction 75 chr16 56396824 56459239 WES breast AMPH 273 amphiphysin 7p14-p13 2687 471 600418 "NP_647477;NP_001626" "NM_139316;NM_001635" "ENSP00000348602;ENSP00000317441" candidate 0 0 0 Eukaryotes 4 0 Cellular processes,Multicellular activities 59 chr7 38424422 38670951 WES liver ANGPT1 284 angiopoietin 1 8q23.1 3392 484 601667 "NP_001137;NP_001186788" "NM_001146;NM_139290;NM_001199859" "ENSP00000428340;ENSP00000297450" candidate 0 0 0 Eukaryotes 4 0 Development,Signal transduction 87 chr8 108264086 108509786 WES melanoma ANK2 287 ankyrin 2, neuronal 4q25-q27 110 493 106410 "NP_001120965;NP_001139;NP_066187" "NM_001127493;NM_001148;NM_020977" "ENSP00000421067;ENSP00000349588" candidate 0 0 0 Last Universal Common Ancestor 25 2 Signal transduction 87 chr4 113970885 114294605 WES bladder ANK3 288 ankyrin 3, node of Ranvier (ankyrin G) 10q21 2715 494 600465 "NP_001191333;NP_066267;NP_001140;NP_001191332" "NM_001204404;NM_020987;NM_001149;NM_001204403" ENSP00000280772 candidate 0 0 0 Last Universal Common Ancestor 22 0 Cellular processes,Signal transduction 89 chr10 61802452 62149296 WES bladder ANKDD1A 348094 ankyrin repeat and death domain containing 1A 15q22.31 14178 28002 - NP_874362 NM_182703 ENSP00000369579 candidate 0 0 0 Last Universal Common Ancestor 0 0 Signal transduction -1 chr15 65207998 65242201 WGS prostate ANKLE2 23141 ankyrin repeat and LEM domain containing 2 12q24.33 - 29101 - NP_055929 NM_015114 ENSP00000350686 candidate 0 0 0 Eukaryotes 5 2 -1 64 chr12 133303831 133338384 WES lymphoma ANKRD20A4 728747 ankyrin repeat domain 20 family, member A4 9q21.11 - 31982 - "NP_001092275;XP_003403870" "NM_001098805;XM_003403822" ENSP00000349891 candidate 0 0 7 Last Universal Common Ancestor 0 0 -1 -1 chr9 69382093 69424173 WGS glioblastoma ANKRD26 22852 ankyrin repeat domain 26 10pter-q22.1 16491 29186 610855 "NP_055730;NP_001242982" "NM_014915;NM_001256053" ENSP00000365255 candidate 0 0 0 Last Universal Common Ancestor 3 0 -1 49 chr10 27294522 27389255 WGS acute myeloid leukemia ANKRD36 375248 ankyrin repeat domain 36 2q11.2 16492 24079 - NP_001157787 "NM_198555;NM_001164315" ENSP00000391950 candidate 0 0 2 Last Universal Common Ancestor 0 0 -1 15 chr2 97779477 97915382 WGS liver ANO4 121601 anoctamin 4 12q23.1 15527 23837 610111 NP_849148 NM_178826 ENSP00000376705 candidate 0 0 0 Eukaryotes 0 0 -1 -1 chr12 101295564 101520845 WES head and neck squamous cell carcinoma APC 324 adenomatous polyposis coli 5q21-q22 1439 583 611731 "NP_001120982;NP_000029;NP_001120983" "NM_001127510;NM_000038;NM_001127511" "ENSP00000257430;ENSP00000427089" known 0 1 0 Last Universal Common Ancestor 104 8 Cell cycle,Cellular metabolism,Cellular processes,Regulation of intracellular processes and metabolism,Signal transduction 72 chr5 112090588 112179820 CGC,HTMS,WES colorectal,desmoid,glioma,liver,other,pancreas,lung,breast,colorectal (hypermutated),colorectal (non-hypermutated),prostate APC2 10297 adenomatosis polyposis coli 2 19p13.3 9802 24036 612034 NP_005874 NM_005883 ENSP00000233607 candidate 0 0 0 Eukaryotes 2 0 Signal transduction 44 chr19 1453001 1470209 WES breast APLNR 187 apelin receptor 11q12 2503 339 600052 NP_005152 "NM_005161;NR_027991" - candidate 0 0 0 Vertebrates 0 0 Signal transduction 40 chr11 57003339 57004478 HTMS breast,lung,ovarian,pancreas,prostate APOA5 116519 apolipoprotein A-V 11q23 6966 17288 606368 "NP_001160070;NP_443200" "NM_001166598;NM_052968" ENSP00000445002 candidate 0 0 0 Vertebrates 3 0 Cellular metabolism,Cellular processes,Development,Multicellular activities,Regulation of intracellular processes and metabolism -1 chr11 116660847 116662414 WGS melanoma APOB 338 apolipoprotein B (including Ag(x) antigen) 2p24-p23 133 603 107730 NP_000375 NM_000384 ENSP00000233242 candidate 0 0 0 Metazoans 34 0 Cellular metabolism,Cellular processes,Regulation of intracellular processes and metabolism 50 chr2 21224605 21265346 WES gastric APOBEC2 10930 apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 2 6p21 7268 605 604797 NP_006780 NM_006789 - candidate 0 0 0 Vertebrates 6 0 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of transcription 49 chr6 41021087 41029607 WES lymphoma AQP7 364 aquaporin 7 9p13 4277 640 602974 NP_001161 NM_001170 ENSP00000297988 candidate 0 0 4 Last Universal Common Ancestor 0 0 Cellular processes,Multicellular activities 13 chr9 33385006 33395195 WGS lymphoma AR 367 androgen receptor Xq12 2437 644 313700 "NP_000035;NP_001011645" "NM_000044;NM_001011645" ENSP00000363822 known 0 0 0 Last Universal Common Ancestor 245 5 Cell cycle,Cellular metabolism,DNA/RNA metabolism and transcription,Development,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction 64 chrX 66764989 66943680 CGC,WES,Amplified prostate ARAP2 116984 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2 4p14 9439 16924 606645 NP_056045 "NM_139182;NM_015230" ENSP00000302895 candidate 0 0 0 Eukaryotes 0 3 Regulation of intracellular processes and metabolism,Signal transduction 78 chr4 36069532 36231108 WGS prostate ARFGEF2 10564 ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) 20q13.13 9250 15853 605371 NP_006411 NM_006420 ENSP00000360985 candidate 0 0 1 Last Universal Common Ancestor 8 0 Cellular processes,Signal transduction 91 chr20 47538427 47649733 WES breast ARHGAP25 9938 Rho GTPase activating protein 25 2p13.3 9805 28951 610587 "NP_001159748;NP_001007232;NP_055697;NP_001159749" "NM_001166276;NM_001007231;NM_014882;NM_001166277" "ENSP00000386911;ENSP00000386241;ENSP00000386863" candidate 0 0 0 Eukaryotes 0 0 Signal transduction 67 chr2 68962332 69053323 WES breast ARHGAP26 23092 Rho GTPase activating protein 26 5q31 5643 17073 605370 "NP_055886;NP_001129080" "NM_015071;NM_001135608" ENSP00000367243 known 1 0 0 Eukaryotes 2 0 Cellular processes,Development,Signal transduction 60 chr5 142150327 142602008 CGC leukemia,myelodysplasia ARHGAP28 79822 Rho GTPase activating protein 28 18p11.31 10961 25509 610592 NP_001010000 "NM_001010000;NM_030672" ENSP00000392660 candidate 0 0 0 Eukaryotes 5 6 Signal transduction 26 chr18 6837348 6912150 WES chronic lymphocytic leukemia ARHGEF10 9639 Rho guanine nucleotide exchange factor (GEF) 10 8p23 9735 14103 608136 NP_055444 NM_014629 ENSP00000340297 candidate 0 0 0 Eukaryotes 2 4 Signal transduction 53 chr8 1806125 1905426 WES colorectal ARHGEF12 23365 Rho guanine nucleotide exchange factor (GEF) 12 11q23.3 9207 14193 604763 "NP_056128;NP_001185594" "NM_015313;NM_001198665" "ENSP00000349056;ENSP00000380942" known 1 0 0 Eukaryotes 4 1 Signal transduction 97 chr11 120278445 120355215 CGC leukemia ARHGEF38 54848 Rho guanine nucleotide exchange factor (GEF) 38 4q24 8613 25968 - "NP_060170;NP_001229658" "NM_017700;NM_001242729" "ENSP00000416125;ENSP00000265154" candidate 0 0 0 Eukaryotes 0 0 Signal transduction 55 chr4 106473923 106599091 WGS chronic lymphocytic leukemia ARID1A 8289 AT rich interactive domain 1A (SWI-like) 1p35.3 4319 11110 603024 "NP_624361;NP_006006" "NM_018450;NM_139135;NM_006015" ENSP00000320485 known 0 1 0 Last Universal Common Ancestor 47 6 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction 108 chr1 27022895 27107244 CGC,WES,WGS kidney,ovarian,bladder,breast,gastric,liver,lymphoma,neuroblastoma,pancreas,prostate ARID1B 57492 AT rich interactive domain 1B (SWI1-like) 6q25.1 10660 18040 - "NP_065783;NP_059989" "NM_020732;NM_017519" ENSP00000055163 candidate 0 0 0 Last Universal Common Ancestor 29 0 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription -1 chr6 157099064 157529022 WES,WGS breast,neuroblastoma,liver ARID2 196528 AT rich interactive domain 2 (ARID, RFX-like) 12q12 16505 18037 609539 NP_689854 NM_152641 ENSP00000335044 known 0 1 0 Metazoans 22 3 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription -1 chr12 46123620 46298858 CGC,WES,WGS liver,breast,pancreas ARNT 405 aryl hydrocarbon receptor nuclear translocator 1q21 524 700 126110 "NP_001184254;NP_001659;NP_848514" "NM_178426;NM_001197325;NM_001668;NM_178427" ENSP00000351407 known 1 0 0 Eukaryotes 50 1 Cell cycle,Cellular metabolism,DNA/RNA metabolism and transcription,Development,Multicellular activities,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction 39 chr1 150784500 150830937 CGC leukemia ARNT2 9915 aryl-hydrocarbon receptor nuclear translocator 2 15q24 - 16876 606036 NP_055677 NM_014862 ENSP00000307479 candidate 0 0 0 Eukaryotes 4 1 Cellular metabolism,DNA/RNA metabolism and transcription,Development,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction 44 chr15 80743217 80886036 WES glioblastoma ARPC1A 10552 actin related protein 2/3 complex, subunit 1A, 41kDa 7q22.1 7252 703 604220 "NP_006400;NP_001177925" "NM_006409;NM_001190996" ENSP00000262942 known 0 0 3 Last Universal Common Ancestor 4 0 Cellular metabolism,Cellular processes,Regulation of intracellular processes and metabolism 100 chr7 98930977 98963549 CGC,Amplified ARVCF 421 armadillo repeat gene deleted in velocardiofacial syndrome 22q11.21 3778 728 602269 NP_001661 NM_001670 ENSP00000263207 candidate 0 0 0 Eukaryotes 8 0 -1 64 chr22 19958754 19978317 WGS liver ASB15 142685 ankyrin repeat and SOCS box containing 15 7q31.31 10669 19767 - NP_563616 NM_080928 ENSP00000275699 candidate 0 0 0 Last Universal Common Ancestor 0 0 Signal transduction -1 chr7 123254557 123277032 WES kidney ASB9 140462 ankyrin repeat and SOCS box containing 9 - 6452 17184 - "NP_001162003;NP_001026909;NP_076992;NP_001162002" "NM_001168531;NM_001031739;NM_024087;NM_001168530" "ENSP00000369855;ENSP00000369850;ENSP00000438943;ENSP00000369852" candidate 0 0 1 Last Universal Common Ancestor 14 0 Signal transduction 56 chrX 15262631 15287996 WGS melanoma ASL 435 argininosuccinate lyase 7cen-q11.2 1948 746 608310 "NP_001020115;NP_000039;NP_001020117;NP_001020114" "NM_001024944;NM_000048;NM_001024946;NM_001024943" "ENSP00000307188;ENSP00000370219" candidate 0 0 0 Last Universal Common Ancestor 7 0 Cell response to stimuli,Cellular metabolism,Cellular processes,Development 64 chr7 65546790 65557896 WES breast,pancreas ASPSCR1 79058 alveolar soft part sarcoma chromosome region, candidate 1 17q25.3 6947 13825 606236 "NP_076988;NP_001238817" "NR_045351;NM_024083;NM_001251888" "ENSP00000306625;ENSP00000302176" known 1 0 0 Eukaryotes 12 0 -1 15 chr17 79935523 79974988 CGC sarcoma ASTN1 460 astrotactin 1 1q25.2 9019 773 600904 "NP_996991;NP_004310" "NM_207108;NM_004319" "ENSP00000354536;ENSP00000395041" candidate 0 0 0 Vertebrates 1 1 Cell motility and interactions 43 chr1 176833423 177133812 WES glioblastoma ASXL1 171023 additional sex combs like 1 (Drosophila) 20q11 16516 18318 612990 "NP_056153;NP_001158075" "NM_015338;NM_001164603" ENSP00000364839 known 0 1 0 Metazoans 21 0 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription 104 chr20 30946579 31025138 CGC,WES leukemia,myelodysplasia,breast,chronic lymphocytic leukemia ATAD1 84896 ATPase family, AAA domain containing 1 10q23.31 12499 25903 614452 NP_116199 NM_032810 ENSP00000339016 candidate 0 0 1 Last Universal Common Ancestor 6 2 -1 -1 chr10 89514447 89574356 WGS glioblastoma ATF1 466 activating transcription factor 1 12q13 440 783 123803 NP_005162 NM_005171 ENSP00000262053 known 1 0 0 Last Universal Common Ancestor 2 2 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription 34 chr12 51173929 51213559 CGC histiocytoma,melanoma ATHL1 80162 ATH1, acid trehalase-like 1 (yeast) 11p15.5 7999 26210 - NP_079368 NM_025092 ENSP00000387185 candidate 0 0 0 Last Universal Common Ancestor 0 1 -1 32 chr11 289817 294746 WGS liver ATIC 471 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase 2q35 3434 794 601731 NP_004035 NM_004044 ENSP00000236959 known 1 0 0 Last Universal Common Ancestor 32 0 Cellular metabolism,DNA/RNA metabolism and transcription,Development 107 chr2 216177220 216214375 CGC lymphoma ATM 472 ataxia telangiectasia mutated 11q22-q23 6347 795 607585 NP_000042 "NM_000051;NM_138292;NM_138293" ENSP00000278616 known 0 1 0 Eukaryotes 124 10 Cell cycle,Cell response to stimuli,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Signal transduction 99 chr11 108098352 108236232 CGC,HTMS,WES,WGS leukemia,lung,chronic lymphocytic leukemia,pancreas,prostate,liver ATN1 1822 atrophin 1 12p13.31 6311 3033 607462 "NP_001931;NP_001007027" "NM_001940;NM_001007026" "ENSP00000349076;ENSP00000379915" candidate 0 0 0 Eukaryotes 151 0 Development 60 chr12 7043339 7050715 WES breast ATP10A 57194 ATPase, class V, type 10A 15q11.2 5790 13542 605855 NP_077816 NM_024490 - candidate 0 0 0 Last Universal Common Ancestor 0 1 Cellular processes,Development,Regulation of intracellular processes and metabolism 65 chr15 25924491 26108243 WES pancreas ATP11A 23250 ATPase, class VI, type 11A 13q34 12059 13552 605868 "NP_115565;NP_056020" "NM_032189;NM_015205" "ENSP00000364796;ENSP00000364781" candidate 0 0 0 Last Universal Common Ancestor 1 0 Cellular processes 49 chr13 113344731 113536375 WES colorectal ATP13A1 57130 ATPase type 13A1 19p13.11 12501 24215 - NP_065143 NM_020410 ENSP00000349877 candidate 0 0 0 Last Universal Common Ancestor 2 3 Cellular processes 99 chr19 19756234 19774475 WES colorectal ATP13A5 344905 ATPase type 13A5 3q29 18597 31789 - NP_940907 NM_198505 ENSP00000341942 candidate 0 0 0 Last Universal Common Ancestor 0 0 Cellular processes -1 chr3 192992834 193096514 WES colorectal ATP2A2 488 ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 12q24.11 161 812 108740 "NP_001672;NP_733765" "NM_001681;NM_170665;NM_001135765" "ENSP00000311186;ENSP00000378872" candidate 0 0 2 Last Universal Common Ancestor 33 4 Cellular processes,Development,Multicellular activities,Regulation of intracellular processes and metabolism,Signal transduction 108 chr12 110719595 110784272 WES leukemia ATP2C2 9914 ATPase, Ca++ transporting, type 2C, member 2 16q24.1 13812 29103 613082 NP_055676 NM_014861 ENSP00000262429 candidate 0 0 0 Last Universal Common Ancestor 2 0 Cellular processes 71 chr16 84402222 84497335 WES lymphoma ATP4A 495 ATPase, H+/K+ exchanging, alpha polypeptide 19q13.1 668 819 137216 NP_000695 NM_000704 ENSP00000262623 candidate 0 0 0 Last Universal Common Ancestor 0 0 Cellular processes 29 chr19 36041734 36054429 WES gastric ATP8B1 5205 ATPase, aminophospholipid transporter, class I, type 8B, member 1 18q21-q22|18q21.31 3867 3706 602397 NP_005594 NM_005603 ENSP00000445359 candidate 0 0 0 Last Universal Common Ancestor 7 0 Cellular metabolism,Cellular processes,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription 93 chr18 55315723 55399039 WES breast ATR 545 ataxia telangiectasia and Rad3 related 3q22-q24 8369 882 601215 NP_001175 NM_001184 ENSP00000343741 candidate 0 0 0 Eukaryotes 93 0 Cell cycle,Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction 66 chr3 142168274 142297546 WGS liver ATRNL1 26033 attractin-like 1 10q26 12504 29063 612869 NP_997186 NM_207303 ENSP00000347152 candidate 0 0 0 Eukaryotes 1 1 -1 51 chr10 116853510 117704287 WGS glioblastoma ATRX 546 alpha thalassemia/mental retardation syndrome X-linked Xq21.1 2069 886 300032 "NP_000480;NP_612114" "NM_000489;NM_138270;NM_138271" "ENSP00000362441;ENSP00000378967" known 0 1 0 Last Universal Common Ancestor 32 2 Cell response to stimuli,Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription 101 chrX 76763832 76972722 CGC,WES glioblastoma,pancreas ATXN3L 92552 ataxin 3-like Xp22.2 - 24173 - NP_001129467 NM_001135995 ENSP00000369996 candidate 0 0 0 Eukaryotes 7 0 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription 30 chrX 13336989 13338053 HTMS breast,lung,ovarian,pancreas,prostate AURKA 6790 aurora kinase A 20q13 4352 11393 603072 "NP_940836;NP_003591;NP_940838;NP_940839;NP_940835;NP_940837" "NM_198434;NM_003600;NM_198436;NM_198437;NM_198433;NM_198435" "ENSP00000216911;ENSP00000379245;ENSP00000379250;ENSP00000379249;ENSP00000321591;ENSP00000379251" known 0 0 1 Last Universal Common Ancestor 97 5 Cell cycle,Cellular metabolism,Cellular processes,Regulation of transcription,Signal transduction 43 chr20 54945217 54963253 CGC,Amplified AVPI1 60370 arginine vasopressin-induced 1 10q24.2 16530 30898 - NP_068378 NM_021732 ENSP00000359660 candidate 0 0 0 Vertebrates 3 1 Cellular metabolism,Cellular processes,Regulation of intracellular processes and metabolism,Signal transduction 98 chr10 99437629 99439662 WGS glioblastoma AXIN1 8312 axin 1 16p13.3 4819 903 603816 "NP_851393;NP_003493" "NM_181050;NM_003502" "ENSP00000262320;ENSP00000346935" candidate 0 0 0 Eukaryotes 83 1 Cell cycle,Development,Multicellular activities,Other,Regulation of intracellular processes and metabolism,Signal transduction 35 chr16 338125 397025 WES,WGS liver B2M 567 beta-2-microglobulin 15q21-q22.2 189 914 109700 NP_004039 NM_004048 - candidate 0 0 0 Vertebrates 26 1 Immune system response 109 chr15 45003745 45007898 WES lymphoma,non-hodgkin lymphoma B3GAT2 135152 beta-1,3-glucuronyltransferase 2 (glucuronosyltransferase S) 6q13 6325 922 607497 NP_542780 NM_080742 - candidate 0 0 0 Eukaryotes 1 0 Cellular metabolism -1 chr6 71571369 71666132 WGS chronic lymphocytic leukemia BABAM1 29086 BRISC and BRCA1 A complex member 1 19p13.11 13702 25008 612766 "NP_054892;NP_001028721" "NM_014173;NM_001033549" "ENSP00000352408;ENSP00000471605" candidate 0 0 0 Eukaryotes 71 4 -1 88 chr19 17379616 17389854 WGS acute myeloid leukemia,chronic lymphocytic leukemia BAG4 9530 BCL2-associated athanogene 4 8p11.23 4861 940 603884 "NP_001191807;NP_004865" "NM_001204878;NM_004874" ENSP00000287322 known 0 0 1 Eukaryotes 42 1 Cell cycle,Cellular metabolism,Cellular processes,Development,Regulation of intracellular processes and metabolism 3 chr8 38034388 38068008 CGC,Amplified BAI3 577 brain-specific angiogenesis inhibitor 3 6q12 4064 945 602684 NP_001695 NM_001704 ENSP00000359630 candidate 0 0 0 Eukaryotes 1 1 Signal transduction 51 chr6 69348568 70098780 HTMS,WES,WGS breast,lung,ovarian,pancreas,prostate,gastric,melanoma BAP1 8314 BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase) 3p21.31-p21.2 4366 950 603089 NP_004647 NM_004656 ENSP00000417132 known 0 1 0 Eukaryotes 56 5 Cell cycle,Cellular metabolism,Cellular processes,Regulation of intracellular processes and metabolism 63 chr3 52436307 52443625 CGC,WES breast,kidney,lung,melanoma BAZ2B 29994 bromodomain adjacent to zinc finger domain, 2B 2q24.2 9295 963 605683 NP_038478 NM_013450 ENSP00000376534 candidate 0 0 0 Eukaryotes 13 1 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription 77 chr2 160176779 160335230 WGS liver BCL10 8915 B-cell CLL/lymphoma 10 1p22 4625 989 603517 NP_003912 NM_003921 ENSP00000359612 known 1 0 0 Metazoans 99 3 Cell cycle,Cell response to stimuli,Cellular metabolism,Cellular processes,DNA/RNA metabolism and transcription,Development,Immune system response,Multicellular activities,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction 59 chr1 85733313 85742035 CGC,WES lymphoma,non-hodgkin lymphoma BCL11A 53335 B-cell CLL/lymphoma 11A (zinc finger protein) 2p16.1 5949 13221 606557 "NP_075044;NP_060484;NP_612569" "NM_022893;NM_018014;NM_138553;NM_138559" "ENSP00000349300;ENSP00000338774;ENSP00000352648" known 1 0 0 Eukaryotes 21 6 Cellular metabolism,DNA/RNA metabolism and transcription,Development,Regulation of intracellular processes and metabolism,Regulation of transcription 82 chr2 60687542 60780405 CGC,WES leukemia,breast BCL11B 64919 B-cell CLL/lymphoma 11B (zinc finger protein) 14q32.2 5950 13222 606558 "NP_612808;NP_075049" "NM_138576;NM_022898" "ENSP00000280435;ENSP00000349723" known 1 0 0 Eukaryotes 21 8 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription 66 chr14 99640491 99737555 CGC leukemia BCL2 596 B-cell CLL/lymphoma 2 18q21.33|18q21.3 1045 990 151430 "NP_000648;NP_000624" "NM_000657;NM_000633" ENSP00000404214 known 1 0 0 Metazoans 138 44 Cell cycle,Cell response to stimuli,Cellular processes,Development,Immune system response,Multicellular activities,Other,Regulation of intracellular processes and metabolism,Signal transduction 83 chr18 60795861 60985899 CGC,WES leukemia,non-hodgkin lymphoma,lymphoma BCL2L10 10017 BCL2-like 10 (apoptosis facilitator) 15q21 6071 993 606910 NP_065129 NM_020396 - candidate 0 0 0 Mammals 40 0 Cell cycle,Development,Multicellular activities,Regulation of intracellular processes and metabolism,Signal transduction 6 chr15 52402048 52404923 WES lymphoma BCL2L2 599 BCL2-like 2 14q11.2-q12 3569 995 601931 "NP_001186768;NP_004041" "NM_001199839;NM_004050" ENSP00000250405 known 0 0 0 Metazoans 21 9 Cell cycle,Development,Multicellular activities,Regulation of intracellular processes and metabolism 93 chr14 23776977 23778171 CGC,Amplified BCL3 602 B-cell CLL/lymphoma 3 19q13.1-q13.2 179 998 109560 NP_005169 NM_005178 ENSP00000164227 known 1 0 0 Last Universal Common Ancestor 55 1 Cell cycle,Cell motility and interactions,Cell response to stimuli,Cellular metabolism,Cellular processes,DNA/RNA metabolism and transcription,Development,Immune system response,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction 66 chr19 45252048 45262869 CGC leukemia BCL5 603 B-cell CLL/lymphoma 5 17q22 - 1000 151441 - - - known 1 0 -1 Last Universal Common Ancestor 0 0 -1 -1 - 0 0 CGC leukemia BCL6 604 B-cell CLL/lymphoma 6 3q27 180 1001 109565 "NP_001124317;NP_001128210;NP_001697" "NM_001130845;NM_138931;NM_001134738;NM_001706" ENSP00000384371 known 1 0 0 Last Universal Common Ancestor 143 8 Cell cycle,Cell motility and interactions,Cell response to stimuli,Cellular metabolism,Cellular processes,DNA/RNA metabolism and transcription,Development,Immune system response,Multicellular activities,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction 101 chr3 187440249 187451481 CGC,WES leukemia,non-hodgkin lymphoma BCL7A 605 B-cell CLL/lymphoma 7A 12q24.13 3243 1004 601406 "NP_066273;NP_001019979" "NM_020993;NM_001024808" - known 1 0 0 Metazoans 2 2 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription 48 chr12 122459998 122497066 CGC non-hodgkin lymphoma BCL9 607 B-cell CLL/lymphoma 9 1q21 4000 1008 602597 NP_004317 NM_004326 ENSP00000234739 known 1 0 0 Metazoans 8 3 Signal transduction 51 chr1 147083636 147096757 CGC,WES leukemia,colorectal BCLAF1 9774 BCL2-associated transcription factor 1 6q22-q23 16544 16863 612588 "NP_001070908;NP_055554;NP_001070909" "NM_001077440;NM_014739;NM_001077441" "ENSP00000229446;ENSP00000435210" candidate 0 0 1 Metazoans 10 1 Cell cycle,Cellular metabolism,DNA/RNA metabolism and transcription,Development,Regulation of intracellular processes and metabolism,Regulation of transcription 106 chr6 136582403 136601004 WES lung BCOR 54880 BCL6 corepressor Xp11.4 6458 20893 300485 "NP_001116856;NP_060215;NP_001116855;NP_001116857" "NM_001123384;NM_017745;NM_001123383;NM_001130139;NM_001123385;NM_020926" "ENSP00000345923;ENSP00000367716;ENSP00000367705;ENSP00000380512" known 0 1 0 Last Universal Common Ancestor 30 3 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription 34 chrX 39911365 39937182 CGC,WES leukemia,retinoblastoma,medulloblastoma,myelodysplasia BCR 613 breakpoint cluster region 22q11|22q11.23 1044 1014 151410 "NP_004318;NP_067585" "NM_004327;NM_021574" ENSP00000303507 known 1 0 0 Eukaryotes 83 0 Cellular metabolism,Cellular processes,Signal transduction 82 chr22 23523148 23657706 CGC,WES leukemia,lymphoma BGN 633 biglycan Xq28 2359 1044 301870 NP_001702 NM_001711 ENSP00000327336 candidate 0 0 0 Last Universal Common Ancestor 18 0 -1 94 chrX 152770090 152773900 WES breast BIRC2 329 baculoviral IAP repeat containing 2 11q22 3419 590 601712 NP_001157 NM_001166 "ENSP00000227758;ENSP00000431723" known 0 0 0 Eukaryotes 31 4 Cell cycle,Development,Regulation of intracellular processes and metabolism,Signal transduction 107 chr11 102220586 102248911 CGC,Amplified BIRC3 330 baculoviral IAP repeat containing 3 11q22 3426 591 601721 "NP_892007;NP_001156" "NM_182962;NM_001165" ENSP00000432907 known 1 0 0 Eukaryotes 59 3 Cell cycle,Development,Regulation of intracellular processes and metabolism,Signal transduction 36 chr11 102195241 102207830 CGC lymphoma BIRC7 79444 baculoviral IAP repeat containing 7 20q13.3 5761 13702 605737 "NP_647478;NP_071444" "NM_139317;NM_022161" "ENSP00000345213;ENSP00000217169" candidate 0 0 0 Eukaryotes 19 0 Cell cycle,Cellular metabolism,Cellular processes,DNA/RNA metabolism and transcription,Development,Regulation of intracellular processes and metabolism,Signal transduction 31 chr20 61867449 61870954 HTMS breast,lung,ovarian,pancreas,prostate BLM 641 Bloom syndrome, RecQ helicase-like 15q26.1 5211 1058 604610 NP_000048 NM_000057 ENSP00000347232 known 0 1 0 Last Universal Common Ancestor 58 3 Cell cycle,Cell response to stimuli,Cellular metabolism,DNA/RNA metabolism and transcription,Development,Immune system response,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction 65 chr15 91290623 91358506 CGC BMPR1A 657 bone morphogenetic protein receptor, type IA 10q22.3 3192 1076 601299 NP_004320 NM_004329 ENSP00000224764 known 0 1 2 Last Universal Common Ancestor 33 3 Cell cycle,Cellular metabolism,Cellular processes,Development,Other,Regulation of intracellular processes and metabolism,Signal transduction 78 chr10 88635776 88683473 CGC BMPR1B 658 bone morphogenetic protein receptor, type IB 4q22-q24 4457 1077 603248 NP_001194 NM_001203 ENSP00000426617 candidate 0 0 1 Last Universal Common Ancestor 69 2 Cellular metabolism,Cellular processes,Development,Immune system response,Multicellular activities,Regulation of intracellular processes and metabolism,Signal transduction 18 chr4 96025576 96075821 WGS chronic lymphocytic leukemia BPTF 2186 bromodomain PHD finger transcription factor 17q24.3 3490 3581 601819 "NP_872579;NP_004450" "NM_182641;NM_004459" "ENSP00000334351;ENSP00000307208" candidate 0 0 0 Eukaryotes 23 1 Cellular metabolism,DNA/RNA metabolism and transcription,Development,Regulation of intracellular processes and metabolism,Regulation of transcription 102 chr17 65821841 65978401 WGS liver BRAF 673 v-raf murine sarcoma viral oncogene homolog B1 7q34 1264 1097 164757 NP_004324 NM_004333 ENSP00000288602 known 1 0 1 Last Universal Common Ancestor 53 0 Cell cycle,Cellular metabolism,Cellular processes,Development,Regulation of intracellular processes and metabolism,Signal transduction 25 chr7 140434400 140624503 CGC,HTMS,WES,WGS cholangiocarcinoma,colorectal,lung,melanoma,ovarian,pilocytic astrocytoma,thyroid,breast,pancreas,prostate,chronic lymphocytic leukemia,colorectal (hypermutated) BRCA1 672 breast cancer 1, early onset 17q21 218 1100 113705 "NP_009229;NP_009225;NP_009228;NP_009230;NP_009231" "NM_007305;NM_007298;NM_007294;NM_007297;NM_007295;NM_007302;NM_007303;NM_007299;NM_007301;NR_027676;NM_007296;NM_007300;NM_007306" "ENSP00000350283;ENSP00000418775;ENSP00000312236;ENSP00000417148;ENSP00000418960" known 0 1 0 Eukaryotes 311 11 Cell cycle,Cell response to stimuli,Cellular metabolism,Cellular processes,DNA/RNA metabolism and transcription,Development,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction 27 chr17 41197698 41276113 CGC,WES ovarian,breast BRCA2 675 breast cancer 2, early onset 13q12.3 2554 1101 600185 NP_000050 NM_000059 ENSP00000369497 known 0 1 0 Eukaryotes 75 6 Cell cycle,Cell response to stimuli,Cellular metabolism,Cellular processes,DNA/RNA metabolism and transcription,Development,Multicellular activities,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction 22 chr13 32890598 32972904 CGC,WES breast,ovarian,pancreas BRD3 8019 bromodomain containing 3 9q34 3327 1104 601541 NP_031397 NM_007371 ENSP00000305918 known 1 0 0 Eukaryotes 21 3 -1 107 chr9 136898715 136918599 CGC lethal midline carcinoma BRD4 23476 bromodomain containing 4 19p13.1 10574 13575 608749 "NP_490597;NP_055114" "NM_058243;NM_014299" "ENSP00000360901;ENSP00000263377" known 1 0 0 Eukaryotes 68 1 -1 108 chr19 15349191 15383910 CGC lethal midline carcinoma BRD8 10902 bromodomain containing 8 5q31 4166 19874 602848 "NP_006687;NP_001157798;NP_631938" "NM_006696;NM_001164326;NM_183359;NM_139199" "ENSP00000394330;ENSP00000230901;ENSP00000254900" candidate 0 0 0 Eukaryotes 10 3 Cell cycle,Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction 99 chr5 137475766 137513354 WGS liver BRE 9577 brain and reproductive organ-expressed (TNFRSF1A modulator) 2p23.2 8498 1106 610497 "NP_954662;NP_954661;NP_954663;NP_004890;NP_954664" "NM_199192;NM_199191;NM_199193;NM_004899;NM_199194" "ENSP00000343412;ENSP00000368945;ENSP00000354699;ENSP00000368953;ENSP00000339371" candidate 0 0 0 Eukaryotes 54 3 Cell cycle,Development,Regulation of intracellular processes and metabolism,Signal transduction 100 chr2 28117424 28550297 WGS liver BRIP1 83990 BRCA1 interacting protein C-terminal helicase 1 17q22.2 5797 20473 605882 NP_114432 NM_032043 - known 0 1 0 Last Universal Common Ancestor 11 3 Cell cycle,Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction 5 chr17 59760660 59938900 CGC BRSK1 84446 BR serine/threonine kinase 1 19q13.4 12533 18994 609235 NP_115806 NM_032430 ENSP00000310649 candidate 0 0 0 Last Universal Common Ancestor 7 0 Cell cycle,Cell response to stimuli,Cellular metabolism,Cellular processes,Development,Signal transduction -1 chr19 55795811 55823433 WES lymphoma BTBD9 114781 BTB (POZ) domain containing 9 6p21 12543 21228 611237 "NP_001165889;NP_689946;NP_001092742;NP_443125" "NM_001172418;NM_152733;NM_001099272;NM_052893" "ENSP00000418751;ENSP00000323408" candidate 0 0 0 Eukaryotes 9 1 -1 -1 chr6 38142764 38565870 WGS melanoma BTG1 694 B-cell translocation gene 1, anti-proliferative 12q22 15912 1130 109580 NP_001722 NM_001731 - known 1 0 0 Eukaryotes 23 1 Cell cycle,Cell motility and interactions,Cellular metabolism,Cellular processes,DNA/RNA metabolism and transcription,Development,Multicellular activities,Regulation of intracellular processes and metabolism,Regulation of transcription 108 chr12 92537859 92539311 CGC,WES leukemia,lymphoma,non-hodgkin lymphoma BTG2 7832 BTG family, member 2 1q32 3357 1131 601597 NP_006754 NM_006763 ENSP00000290551 candidate 0 0 0 Eukaryotes 34 9 Cell cycle,Cellular metabolism,Cellular processes,DNA/RNA metabolism and transcription,Development,Regulation of intracellular processes and metabolism,Regulation of transcription 93 chr1 203274735 203276563 WES non-hodgkin lymphoma BUB1B 701 budding uninhibited by benzimidazoles 1 homolog beta (yeast) 15q15 4176 1149 602860 NP_001202 NM_001211 ENSP00000287598 known 0 1 0 Eukaryotes 61 3 Cell cycle,Cellular metabolism,Cellular processes,Regulation of intracellular processes and metabolism,Signal transduction 39 chr15 40457252 40512957 CGC C10orf108 414235 chromosome 10 open reading frame 108 10p15.3 18528 30724 - - "NM_001012714;NR_027152;NR_027151" - candidate 0 0 -1 Opisthokonts 0 0 -1 -1 - 0 0 WGS chronic lymphocytic leukemia C10orf137 26098 chromosome 10 open reading frame 137 10q26.13 10694 24640 - "NP_056423;NP_001189367" "NM_030897;NM_015608;NM_001202438" "ENSP00000349244;ENSP00000336727" candidate 0 0 0 Eukaryotes 69 4 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription 74 chr10 127408377 127452038 WES colorectal C10orf2 56652 chromosome 10 open reading frame 2 10q24 5830 1160 606075 "NP_001157286;NP_068602;NP_001157285;NP_001157284" "NM_001163814;NM_021830;NM_001163813;NM_001163812" "ENSP00000359248;ENSP00000309595" candidate 0 0 0 Last Universal Common Ancestor 10 4 Cellular metabolism,DNA/RNA metabolism and transcription 38 chr10 102747968 102753264 WES leukemia C10orf95 79946 chromosome 10 open reading frame 95 10q24.32 10701 25880 - NP_079162 NM_024886 ENSP00000239125 candidate 0 0 0 Mammals 2 0 -1 3 chr10 104210217 104211225 WGS liver C11orf10 746 chromosome 11 open reading frame 10 11q12.2 12602 1164 - NP_055021 NM_014206 ENSP00000257262 candidate 0 0 1 Metazoans 1 0 -1 109 chr11 61557270 61558074 WGS breast C11orf30 56946 chromosome 11 open reading frame 30 11q13.5 10544 18071 608574 NP_064578 NM_020193 ENSP00000334130 known 0 0 0 Eukaryotes 19 1 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription 12 chr11 76157983 76261187 CGC,Amplified C12orf35 55196 chromosome 12 open reading frame 35 12p11.21 7691 25559 - NP_060639 NM_018169 ENSP00000310338 candidate 0 0 0 Vertebrates 5 2 -1 88 chr12 32133890 32145466 WES lymphoma C12orf51 283450 chromosome 12 open reading frame 51 12q24.13 8170 26611 - NP_001103132 "NM_173813;NM_001109662" ENSP00000449784 candidate 0 0 0 Eukaryotes 1 1 Cellular metabolism,Cellular processes 80 chr12 112600194 112757291 WGS liver C12orf63 374467 chromosome 12 open reading frame 63 12q23.1 13484 24777 - "XP_003403698;XP_003118990" "XM_003403650;NM_198520;XM_003118942" ENSP00000345466 candidate 0 0 0 Metazoans 1 0 -1 -1 chr12 97114186 97216599 WES melanoma C12orf9 93669 chromosome 12 open reading frame 9 - - 15949 - - - - known 1 0 -1 - 0 0 -1 -1 - 0 0 CGC lipoma C13orf26 122046 chromosome 13 open reading frame 26 13q12.3 17551 28622 - NP_689538 NM_152325 - candidate 0 0 0 Metazoans 0 0 -1 -1 chr13 31506853 31549041 WGS glioblastoma C14orf102 55051 chromosome 14 open reading frame 102 14q32.11 12625 20186 - "NP_950244;NP_060440" "NM_199043;NM_017970" ENSP00000350579 candidate 0 0 0 Eukaryotes 3 0 -1 2 chr14 90744683 90798248 WGS lung C14orf105 55195 chromosome 14 open reading frame 105 14q22.3 12628 20189 - NP_060638 NM_018168 ENSP00000216445 candidate 0 0 0 Metazoans 0 0 -1 4 chr14 57938076 57960433 WGS glioblastoma C14orf159 80017 chromosome 14 open reading frame 159 14q32.11 16612 20498 - "NP_001095839;NP_001095836;NP_001095838;NP_001095837;NP_079228" "NM_001102369;NM_001102366;NM_001102368;NM_001102367;NM_024952" "ENSP00000428974;ENSP00000427953;ENSP00000256324;ENSP00000429453;ENSP00000404343" candidate 0 0 0 Last Universal Common Ancestor 1 1 -1 89 chr14 91626639 91691174 WGS glioblastoma C14orf39 317761 chromosome 14 open reading frame 39 14q23.1 8504 19849 - NP_777638 NM_174978 ENSP00000324920 candidate 0 0 0 Vertebrates 0 1 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription -1 chr14 60903566 60951796 WGS chronic lymphocytic leukemia C14orf49 161176 chromosome 14 open reading frame 49 14q32.13 12652 19861 610861 NP_689805 NM_152592 ENSP00000334308 candidate 0 0 0 Eukaryotes 0 2 -1 -1 chr14 95884166 95942158 WES prostate C15orf2 23742 chromosome 15 open reading frame 2 15q11-q13 8506 1190 610922 NP_061831 NM_018958 ENSP00000333735 candidate 0 0 0 Mammals 0 0 Development,Multicellular activities 59 chr15 24921015 24924482 WES colorectal C15orf55 256646 chromosome 15 open reading frame 55 15q14 10606 29919 608963 NP_786883 NM_175741 ENSP00000329448 known 1 0 0 Vertebrates 45 1 -1 -1 chr15 34640169 34649689 CGC lethal midline carcinoma C15orf57 90416 chromosome 15 open reading frame 57 15q15.1 14473 28295 - "NP_443081;NP_001074261;NP_001074260" "NM_052849;NM_001080792;NM_001080791" "ENSP00000397515;ENSP00000350695" candidate 0 0 0 Metazoans 1 4 -1 -1 chr15 40846173 40855226 WGS glioblastoma C17orf108 201229 chromosome 17 open reading frame 108 17q11.2 - 27314 - NP_001070148 NM_001076680 - candidate 0 0 0 Metazoans 1 0 -1 59 chr17 26207300 26209720 WES lung C18orf1 753 chromosome 18 open reading frame 1 18p11.21 7358 1224 606571 "NP_852146;NP_852148;NP_004329;NP_001003675;NP_852147;NP_001003674" "NM_181481;NM_181483;NM_004338;NM_001003675;NM_181482;NM_001003674" "ENSP00000382740;ENSP00000382741" candidate 0 0 0 Metazoans 1 4 -1 81 chr18 13438236 13645653 WGS melanoma C18orf34 374864 chromosome 18 open reading frame 34 18q12.1 12691 29588 - "NP_001098998;NP_945346" "NM_001105528;NM_198995" "ENSP00000385591;ENSP00000300227" candidate 0 0 0 Metazoans 0 0 -1 -1 chr18 30517978 30992052 WES liver C19orf26 255057 chromosome 19 open reading frame 26 19p13.3 16627 28617 - NP_689982 NM_152769 ENSP00000215376 candidate 0 0 0 Vertebrates 0 0 -1 1 chr19 1230895 1236081 WES head and neck squamous cell carcinoma C1orf127 148345 chromosome 1 open reading frame 127 1p36.22 8780 26730 - NP_001164225 "NM_173507;NM_001170754" ENSP00000366203 candidate 0 0 0 Vertebrates 0 0 -1 -1 chr1 11007723 11036312 WGS melanoma C1orf168 199920 chromosome 1 open reading frame 168 1p32.2 14120 27295 - NP_001004303 NM_001004303 ENSP00000345972 candidate 0 0 0 Vertebrates 2 2 -1 -1 chr1 57185847 57258476 WES gastric C1orf64 149563 chromosome 1 open reading frame 64 1p36.13 14492 28339 - NP_849162 NM_178840 - candidate 0 0 0 Mammals 1 0 -1 -1 chr1 16330799 16332838 WES breast C1QL2 165257 complement component 1, q subcomponent-like 2 2q14.2 12713 24181 614330 NP_872334 NM_182528 ENSP00000272520 candidate 0 0 0 Eukaryotes 0 0 Cellular processes -1 chr2 119914381 119915845 WES head and neck squamous cell carcinoma C20orf62 140834 chromosome 20 open reading frame 62 20q13.12 18555 16195 - NP_848571 NM_178476 - candidate 0 0 -1 Primates 0 0 -1 -1 - 0 0 WGS lung C2CD3 26005 C2 calcium-dependent domain containing 3 11q13.4 16811 24564 - NP_056346 NM_015531 ENSP00000323339 candidate 0 0 0 Eukaryotes 0 1 -1 68 chr11 73748521 73881837 WES pancreas C2orf44 80304 chromosome 2 open reading frame 44 2p23.3 7972 26157 - "NP_001135791;NP_079479" "NM_001142319;NM_025203" "ENSP00000385816;ENSP00000295148" known 1 0 0 Metazoans 25 2 -1 29 chr2 24253806 24262364 CGC lung C4orf50 389197 chromosome 4 open reading frame 50 4p16.2 13538 33766 - "XP_003119970;XP_003118572" "NM_207405;XM_003119922;XM_003118524" ENSP00000317287 candidate 0 0 0 Mammals 0 0 -1 -1 chr4 5961105 5982065 WES pancreas C5orf42 65250 chromosome 5 open reading frame 42 5p13.2 7822 25801 - NP_075561 NM_023073 ENSP00000389014 candidate 0 0 0 Metazoans 9 0 -1 2 chr5 37107707 37247800 WES breast C6orf103 79747 chromosome 6 open reading frame 103 6q24.3 - 21212 - NP_078970 NM_024694 ENSP00000381036 candidate 0 0 0 Eukaryotes 1 2 Cellular metabolism 13 chr6 146920177 147136350 WGS lung C6orf170 221322 chromosome 6 open reading frame 170 6q22.31 12867 21485 - NP_689943 NM_152730 ENSP00000275159 candidate 0 0 0 Metazoans 2 0 Regulation of intracellular processes and metabolism,Signal transduction -1 chr6 121401920 121655576 WES glioblastoma C7orf23 79161 chromosome 7 open reading frame 23 7q21.12 12911 21707 - NP_077291 NM_024315 ENSP00000257637 candidate 0 0 0 Eukaryotes 0 0 -1 100 chr7 86825955 86848819 WES head and neck squamous cell carcinoma C8orf4 56892 chromosome 8 open reading frame 4 8p11.2 9650 1357 607702 NP_064515 NM_020130 ENSP00000319914 known 0 0 0 Vertebrates 3 4 Cell cycle 29 chr8 40011052 40011369 CGC,Amplified C8orf46 254778 chromosome 8 open reading frame 46 8q13.1 14565 28498 - NP_689978 NM_152765 ENSP00000302260 candidate 0 0 0 Vertebrates 0 2 -1 -1 chr8 67405884 67428308 WES melanoma CACNA1E 777 calcium channel, voltage-dependent, R type, alpha 1E subunit 1q25-q31 3006 1392 601013 "NP_001192223;NP_000712;NP_001192222" "NM_001205294;NM_000721;NM_001205293" ENSP00000434814 known 0 0 0 Last Universal Common Ancestor 4 0 Cellular processes,Multicellular activities 10 chr1 181452881 181767967 CGC,Amplified CACNA1F 778 calcium channel, voltage-dependent, L type, alpha 1F subunit Xp11.23 2119 1393 300110 NP_005174 NM_005183 "ENSP00000321618;ENSP00000365427;ENSP00000365441" candidate 0 0 0 Last Universal Common Ancestor 2 0 Cell cycle,Cell response to stimuli,Cellular processes,Development,Regulation of intracellular processes and metabolism 3 chrX 49061600 49088390 WES breast CACNA1H 8912 calcium channel, voltage-dependent, T type, alpha 1H subunit 16p13.3 7442 1395 607904 "NP_001005407;NP_066921" "NM_001005407;NM_021098" "ENSP00000351401;ENSP00000334198" candidate 0 0 0 Last Universal Common Ancestor 9 0 Cell cycle,Cellular processes,Development,Multicellular activities 0 chr16 1203738 1270991 WES glioblastoma CACNA2D1 781 calcium channel, voltage-dependent, alpha 2/delta subunit 1 7q21-q22 245 1399 114204 NP_000713 NM_000722 ENSP00000348589 candidate 0 0 0 Eukaryotes 3 4 Cellular processes 31 chr7 81579711 82072775 WES pancreas CACNA2D3 55799 calcium channel, voltage-dependent, alpha 2/delta subunit 3 3p21.1 5907 15460 606399 NP_060868 NM_018398 ENSP00000419101 candidate 0 0 0 Eukaryotes 1 0 Cellular processes 20 chr3 54156741 55108230 WES colorectal CALR 811 calreticulin 19p13.3-p13.2 169 1455 109091 NP_004334 NM_004343 ENSP00000320866 candidate 0 0 0 Eukaryotes 81 8 Cell cycle,Cellular metabolism,Cellular processes,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription 109 chr19 13049494 13054724 WES lymphoma CAMTA1 23261 calmodulin binding transcription activator 1 1p36.31-p36.23 16681 18806 611501 "NP_001229630;NP_056030;NP_001182492" "NM_001242701;NM_015215;NM_001195563;NR_038934" - known 1 0 0 Eukaryotes 1 6 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription 32 chr1 6845591 7812591 CGC,WES epitheliod hemangioendothelioma,lymphoma CANT1 124583 calcium activated nucleotidase 1 17q25.3 13003 19721 613165 "NP_001153244;NP_620148;NP_001153245" "NM_001159772;NM_138793;NM_001159773" "ENSP00000376241;ENSP00000307674" known 1 0 0 Eukaryotes 1 4 Regulation of intracellular processes and metabolism,Signal transduction 94 chr17 76989635 76993704 CGC prostate CARD10 29775 caspase recruitment domain family, member 10 22q13.1 6233 16422 607209 NP_055365 NM_014550 ENSP00000251973 candidate 0 0 0 Eukaryotes 1 6 Cell cycle,Regulation of intracellular processes and metabolism,Signal transduction 47 chr22 37887200 37915207 WES pancreas CARD11 84433 caspase recruitment domain family, member 11 7p22 6234 16393 607210 NP_115791 NM_032415 ENSP00000380150 known 1 0 0 Eukaryotes 29 1 Cell cycle,Cellular metabolism,DNA/RNA metabolism and transcription,Development,Immune system response,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction -1 chr7 2946275 2987422 CGC,WES lymphoma,kidney,non-hodgkin lymphoma CARD6 84674 caspase recruitment domain family, member 6 5p13.1 9871 16394 609986 NP_115976 NM_032587 ENSP00000254691 candidate 0 0 0 Mammals 6 0 Cell cycle -1 chr5 40841485 40854545 WGS melanoma CARS 833 cysteinyl-tRNA synthetase 11p15.5 464 1493 123859 "NP_001742;NP_001181926;NP_644802;NP_001014437" "NM_001751;NR_036542;NM_001194997;NM_139273;NM_001014438;NM_001014437" "ENSP00000369897;ENSP00000380300;ENSP00000278224" known 1 0 0 Last Universal Common Ancestor 10 1 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of transcription 109 chr11 3022347 3069232 CGC lymphoma CASC5 57082 cancer susceptibility candidate 5 15q14 10634 24054 609173 "NP_653091;NP_733468" "NM_144508;NM_170589" "ENSP00000382576;ENSP00000335463" known 1 0 0 Metazoans 19 3 Cell cycle,Development,Multicellular activities 10 chr15 40897309 40954383 CGC leukemia CASP8 841 caspase 8, apoptosis-related cysteine peptidase 2q33-q34 3459 1509 601763 "NP_001073594;NP_203522;NP_001219;NP_203519;NP_203520;NP_001073593" "NM_001080125;NM_033358;NM_001228;NM_033355;NM_033356;NM_033357;NM_001080124" "ENSP00000264274;ENSP00000351273;ENSP00000325722;ENSP00000376087" candidate 0 0 0 Last Universal Common Ancestor 156 2 Cell cycle,Cellular metabolism,Development,Regulation of intracellular processes and metabolism,Signal transduction 60 chr2 202122955 202151314 WES breast,colorectal (hypermutated),head and neck squamous cell carcinoma CATSPERB 79820 cation channel, sperm-associated, beta 14q32.12 16613 20500 611169 NP_079040 NM_024764 ENSP00000256343 candidate 0 0 0 Metazoans 0 2 Development,Multicellular activities 22 chr14 92047236 92195823 WES breast CBFA2T3 863 "core-binding factor, runt domain, alpha subunit 2; translocated to, 3" 16q24 4847 1537 603870 "NP_787127;NP_005178" "NM_175931;NM_005187" "ENSP00000268679;ENSP00000332122" known 1 0 0 Opisthokonts 9 0 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription 55 chr16 88943387 89043215 CGC leukemia CBFB 865 core-binding factor, beta subunit 16q22.1 418 1539 121360 "NP_074036;NP_001746" "NM_022845;NM_001755" "ENSP00000290858;ENSP00000415151" known 1 0 0 Metazoans 31 7 Cellular metabolism,DNA/RNA metabolism and transcription 107 chr16 67063311 67132678 CGC,HTMS,WES leukemia,breast,lung,ovarian,pancreas,prostate CBL 867 Cas-Br-M (murine) ecotropic retroviral transforming sequence 11q23.3 1320 1541 165360 NP_005179 NM_005188 ENSP00000264033 known 1 1 0 Metazoans 269 0 Cellular metabolism,Cellular processes,Regulation of intracellular processes and metabolism,Signal transduction 26 chr11 119077128 119170488 CGC leukemia,myelodysplasia CBLB 868 Cas-Br-M (murine) ecotropic retroviral transforming sequence b 3q13.11 5136 1542 604491 NP_733762 NM_170662 ENSP00000377595 known 0 1 0 Metazoans 63 0 Cellular processes,Signal transduction 83 chr3 105377817 105586421 CGC leukemia CBLC 23624 Cas-Br-M (murine) ecotropic retroviral transforming sequence c 19q13.2 9765 15961 608453 "NP_036248;NP_001124324" "NM_012116;NM_001130852" "ENSP00000340250;ENSP00000270279" known 0 1 0 Mammals 15 1 Cellular metabolism,Cellular processes,Regulation of intracellular processes and metabolism,Signal transduction 1 chr19 45281189 45303697 CGC,HTMS leukemia,breast,lung,ovarian,pancreas,prostate CC2D2A 57545 coiled-coil and C2 domain containing 2A 4p15.32 - 29253 612013 "NP_001073991;NP_065836;NP_001158192" "NM_001080522;NM_020785;NM_001164720" "ENSP00000421809;ENSP00000424368;ENSP00000426109" candidate 0 0 0 Eukaryotes 1 3 -1 -1 chr4 15480335 15603045 WES pancreas CCDC117 150275 coiled-coil domain containing 117 22q12.1 8167 26599 - NP_775781 NM_173510 ENSP00000249064 candidate 0 0 0 Vertebrates 3 0 -1 -1 chr22 29168838 29182311 WGS breast CCDC168 643677 coiled-coil domain containing 168 13q33.1 - 26851 - NP_001139669 NM_001146197 - candidate 0 0 0 - 2 0 -1 -1 chr13 103381804 103411282 WES glioblastoma CCDC41 51134 coiled-coil domain containing 41 12q22 14869 17966 - "NP_001035858;NP_057206" "NM_001042399;NM_016122" "ENSP00000344655;ENSP00000380911" candidate 0 0 0 Eukaryotes 0 5 -1 39 chr12 94702592 94806266 WES pancreas CCDC6 8030 coiled-coil domain containing 6 10q21 9064 18782 601985 NP_005427 NM_005436 ENSP00000263102 known 1 0 0 Eukaryotes 11 4 -1 80 chr10 61552678 61666182 CGC dominant,leukemia,lung,thyroid CCDC63 160762 coiled-coil domain containing 63 12q24.11 8765 26669 - NP_689804 NM_152591 ENSP00000312399 candidate 0 0 0 Eukaryotes 0 0 -1 -1 chr12 111291209 111345277 WES melanoma CCDC85A 114800 coiled-coil domain containing 85A 2p16.1 - 29400 - NP_001073902 NM_001080433 ENSP00000384040 candidate 0 0 0 Metazoans 5 0 -1 -1 chr2 56411760 56611487 WGS breast CCDC99 54908 coiled-coil domain containing 99 5q35.1 8623 26010 - NP_060255 NM_017785 ENSP00000265295 candidate 0 0 0 Eukaryotes 8 3 -1 14 chr5 169015421 169031208 WGS liver CCKAR 886 cholecystokinin A receptor 4p15.1-p15.2 322 1570 118444 NP_000721 NM_000730 ENSP00000295589 candidate 0 0 0 Metazoans 4 0 Cell cycle,Cell motility and interactions,Cell response to stimuli,Development,Regulation of intracellular processes and metabolism,Signal transduction 30 chr4 26483263 26491889 HTMS breast,lung,ovarian,pancreas,prostate CCKBR 887 cholecystokinin B receptor 11p15.4 323 1571 118445 NP_795344 NM_176875 ENSP00000335544 candidate 0 0 0 Metazoans 12 2 Cell cycle,Cell response to stimuli,Regulation of intracellular processes and metabolism,Signal transduction 58 chr11 6281159 6292770 HTMS breast,lung,ovarian,pancreas,prostate CCNB1IP1 57820 cyclin B1 interacting protein 1, E3 ubiquitin protein ligase 14q11.2 7000 19437 608249 "NP_878272;NP_878271;NP_067001;NP_878269" "NM_182852;NM_182851;NM_021178;NM_182849" "ENSP00000351810;ENSP00000337396;ENSP00000409896" known 1 0 2 Eukaryotes 8 1 -1 99 chr14 20779712 20784682 CGC leiomyoma CCND1 595 cyclin D1 11q13 1346 1582 168461 NP_444284 NM_053056 ENSP00000227507 known 1 0 0 Last Universal Common Ancestor 24 31 Cell cycle,Cell response to stimuli,Cellular metabolism,Cellular processes,Development,Regulation of intracellular processes and metabolism,Signal transduction 73 chr11 69456082 69466047 CGC,WES,WGS,Amplified breast,leukemia,lung,myeloma CCND2 894 cyclin D2 12p13 451 1583 123833 NP_001750 NM_001759 ENSP00000261254 known 1 0 1 Last Universal Common Ancestor 28 21 Cell cycle,Cellular metabolism,Cellular processes,Regulation of intracellular processes and metabolism,Signal transduction 105 chr12 4383207 4409172 CGC,WGS,Amplified non-hodgkin lymphoma,chronic lymphocytic leukemia CCND3 896 cyclin D3 6p21 452 1585 123834 "NP_001129597;NP_001129489;NP_001751;NP_001129598" "NM_001136125;NM_001136017;NM_001760;NM_001136126" "ENSP00000362079;ENSP00000397545;ENSP00000401595;ENSP00000362082" known 1 0 0 Last Universal Common Ancestor 55 4 Cell cycle,Cellular metabolism,Cellular processes,Regulation of intracellular processes and metabolism,Signal transduction 108 chr6 41903681 41909387 CGC,WES myeloma,breast,leukemia,lymphoma,non-hodgkin lymphoma CCNE1 898 cyclin E1 19q12 455 1589 123837 NP_001229 "NM_001238;NM_057182" ENSP00000262643 known 1 0 0 Last Universal Common Ancestor 74 13 Cell cycle,Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction 31 chr19 30303594 30314681 CGC,Amplified ovarian CCNL1 57018 cyclin L1 3q25.31 10814 20569 613384 NP_064703 NM_020307 - candidate 0 0 0 Eukaryotes 9 7 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription 101 chr3 156866033 156877883 WES gastric CCR3 1232 chemokine (C-C motif) receptor 3 3p21.3 3167 1604 601268 "NP_847898;NP_001828;NP_847899;NP_001158152" "NM_178328;NM_001837;NM_178329;NM_001164680" "ENSP00000440097;ENSP00000441600;ENSP00000379271" candidate 0 0 0 Mammals 12 0 Cell motility and interactions,Cell response to stimuli,Immune system response,Regulation of intracellular processes and metabolism,Signal transduction 19 chr3 46305895 46307714 HTMS breast,lung,ovarian,pancreas,prostate CCR5 1234 chemokine (C-C motif) receptor 5 (gene/pseudogene) 3p21.31 3223 1606 601373 "NP_000570;NP_001093638" "NM_000579;NM_001100168" ENSP00000343985 candidate 0 0 1 Vertebrates 55 0 Cell motility and interactions,Cell response to stimuli,Immune system response,Other,Regulation of intracellular processes and metabolism,Signal transduction 1 chr3 46414394 46415449 HTMS breast,lung,ovarian,pancreas,prostate CCT6B 10693 chaperonin containing TCP1, subunit 6B (zeta 2) 17q12 9873 1621 610730 "NP_001180459;NP_006575;NP_001180458" "NM_001193530;NM_006584;NM_001193529" "ENSP00000398044;ENSP00000400917;ENSP00000327191" candidate 0 0 2 Last Universal Common Ancestor 2 2 Cellular metabolism,Cellular processes,Development,Multicellular activities 51 chr17 33255070 33288412 WES lymphoma CCT8 10694 chaperonin containing TCP1, subunit 8 (theta) 21q22.11 10816 1623 - NP_006576 NM_006585 ENSP00000286788 candidate 0 0 1 Last Universal Common Ancestor 27 0 Cellular metabolism,Cellular processes 108 chr21 30428799 30445911 WGS prostate CD109 135228 CD109 molecule 6q13 10590 21685 608859 "NP_598000;NP_001153060;NP_001153059" "NM_133493;NM_001159588;NM_001159587" "ENSP00000388062;ENSP00000404475" candidate 0 0 0 Last Universal Common Ancestor 1 3 -1 -1 chr6 74405939 74533354 WES colorectal CD1B 910 CD1b molecule 1q22-q23 1775 1635 188360 NP_001755 NM_001764 ENSP00000357150 candidate 0 0 0 Mammals 4 0 -1 21 chr1 158298710 158301213 WGS melanoma CD1E 913 CD1e molecule 1q22-q23 1781 1638 188411 "NP_001172039;NP_001036050;NP_001036049;NP_001036052;NP_001172043;NP_001172042;NP_001172037;NP_001036048;NP_001172036;NP_112155;NP_001172041;NP_001172044;NP_001036051" "NM_001185110;NM_001042585;NM_001042584;NM_001042587;NM_001185114;NM_001185113;NM_001185108;NM_001042583;NM_001185107;NM_030893;NM_001185112;NM_001185115;NM_001042586" "ENSP00000357142;ENSP00000357143;ENSP00000357145;ENSP00000357148;ENSP00000402906" candidate 0 0 0 Mammals 2 0 -1 24 chr1 158323779 158326683 WGS prostate CD274 29126 CD274 molecule 9p24 5655 17635 605402 NP_054862 NM_014143 "ENSP00000370985;ENSP00000370989" known 1 0 0 Vertebrates 3 6 Cell cycle,Immune system response,Regulation of intracellular processes and metabolism,Signal transduction -1 chr9 5456114 5466828 CGC lymphoma CD36 948 CD36 molecule (thrombospondin receptor) 7q11.2 1430 1663 173510 "NP_001120915;NP_001001548;NP_001120916;NP_000063;NP_001001547" "NM_001127443;NM_001001548;NM_001127444;NM_000072;NM_001001547" "ENSP00000378268;ENSP00000308165;ENSP00000411411;ENSP00000392298" candidate 0 0 0 Eukaryotes 1 3 Cellular processes,Multicellular activities 54 chr7 80276057 80303460 WES chronic lymphocytic leukemia,lymphoma CD58 965 CD58 molecule 1p13 1081 1688 153420 "NP_001138294;NP_001770" "NR_026665;NM_001144822;NM_001779" "ENSP00000409080;ENSP00000358501" candidate 0 0 0 Vertebrates 8 0 -1 57 chr1 117064526 117113594 WES lymphoma,non-hodgkin lymphoma CD6 923 CD6 molecule 11q13 1724 1691 186720 "NP_001241680;NP_001241679;NP_006716" "NM_001254751;NM_001254750;NR_045638;NM_006725" ENSP00000323280 candidate 0 0 0 Vertebrates 3 0 -1 67 chr11 60739338 60786787 WGS lymphoma CD70 970 CD70 molecule 19p13 18515 11937 602840 NP_001243 NM_001252 ENSP00000245903 candidate 0 0 0 Mammals 0 0 Cell cycle,Development,Regulation of intracellular processes and metabolism,Signal transduction 28 chr19 6586034 6591013 WES lymphoma,non-hodgkin lymphoma CD74 972 CD74 molecule, major histocompatibility complex, class II invariant chain 5q32 825 1697 142790 "NP_001020329;NP_001020330;NP_004346" "NM_001025158;NM_001025159;NM_004355" "ENSP00000367026;ENSP00000230685" known 1 0 0 Eukaryotes 20 0 Cell cycle,Cellular metabolism,Cellular processes,Development,Immune system response,Regulation of intracellular processes and metabolism,Signal transduction 104 chr5 149782127 149792312 CGC lung CD79A 973 CD79a molecule, immunoglobulin-associated alpha 19q13.2 203 1698 112205 "NP_067612;NP_001774" "NM_021601;NM_001783" ENSP00000221972 known 1 0 0 Vertebrates 1 1 Cell response to stimuli,Development,Immune system response,Signal transduction 52 chr19 42381375 42385044 CGC lymphoma CD79B 974 CD79b molecule, immunoglobulin-associated beta 17q23 922 1699 147245 "NP_067613;NP_001035022;NP_000617" "NM_021602;NM_001039933;NM_000626" "ENSP00000006750;ENSP00000376544" known 1 0 0 Vertebrates 0 0 Signal transduction 31 chr17 62006589 62009621 CGC,WES lymphoma,non-hodgkin lymphoma CD8A 925 CD8a molecule 2p12 1737 1706 186910 "NP_001759;NP_001139345;NP_741969" "NM_001768;NR_027353;NM_001145873;NM_171827" "ENSP00000386559;ENSP00000283635" candidate 0 0 0 Vertebrates 2 2 Immune system response,Signal transduction 66 chr2 87013046 87017948 WGS chronic lymphocytic leukemia CD93 22918 CD93 molecule 20p11.21 396 15855 120577 NP_036204 NM_012072 ENSP00000246006 candidate 0 0 0 Eukaryotes 6 0 Cellular processes,Immune system response 92 chr20 23064898 23066829 WES colorectal CDC25C 995 cell division cycle 25 homolog C (S. pombe) 5q31 1146 1727 157680 "NP_073720;NP_001781" "NM_022809;NM_001790" "ENSP00000321656;ENSP00000345205" candidate 0 0 0 Eukaryotes 42 1 Cell cycle,Cellular metabolism,Cellular processes,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Signal transduction 33 chr5 137621384 137666869 HTMS breast,lung,ovarian,pancreas,prostate CDC27 996 cell division cycle 27 homolog (S. cerevisiae) 17q21.32 304 1728 116946 "NP_001107563;NP_001247" "NM_001114091;NM_001256" ENSP00000066544 candidate 0 0 2 Last Universal Common Ancestor 84 6 Cell cycle,Cellular metabolism,Regulation of intracellular processes and metabolism 92 chr17 45198304 45259006 WES,WGS colorectal (hypermutated),lymphoma CDC42 998 cell division cycle 42 (GTP binding protein, 25kDa) 1p36.1 309 1736 116952 "NP_001782;NP_426359;NP_001034891" "NM_001791;NM_044472;NM_001039802" "ENSP00000341072;ENSP00000383118;ENSP00000314458" candidate 0 0 10 Last Universal Common Ancestor 223 12 Cellular processes,Development,Regulation of intracellular processes and metabolism,Signal transduction 109 chr1 22404972 22418007 WGS acute myeloid leukemia CDC42BPB 9578 CDC42 binding protein kinase beta (DMPK-like) 14q32.3 8516 1738 614062 NP_006026 NM_006035 ENSP00000355237 candidate 0 0 0 Last Universal Common Ancestor 22 3 Cellular metabolism,Cellular processes,Development,Signal transduction 63 chr14 103400052 103523510 WES pancreas CDC42BPG 55561 CDC42 binding protein kinase gamma (DMPK-like) 11q13.1 13013 29829 613991 NP_059995 NM_017525 ENSP00000345133 candidate 0 0 0 Last Universal Common Ancestor 10 0 Cellular metabolism,Cellular processes,Signal transduction -1 chr11 64591948 64612041 WES pancreas CDC6 990 cell division cycle 6 homolog (S. cerevisiae) 17q21.3 4022 1744 602627 NP_001245 NM_001254 ENSP00000209728 known 0 0 0 Last Universal Common Ancestor 46 3 Cell cycle,Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction 43 chr17 38445673 38458250 CGC,WGS,Amplified breast CDC73 79577 cell division cycle 73, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae) 1q25 9581 16783 607393 NP_078805 NM_024529 ENSP00000356405 known 0 1 0 Eukaryotes 79 1 Cell cycle,Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism 11 chr1 193091331 193219002 CGC thyroid CDH1 999 cadherin 1, type 1, E-cadherin (epithelial) 16q22.1 1885 1748 192090 NP_004351 NM_004360 ENSP00000261769 known 0 1 0 Last Universal Common Ancestor 125 7 Cell motility and interactions,Cellular processes,Regulation of intracellular processes and metabolism 55 chr16 68771319 68867399 CGC,HTMS,WES breast,gastric,sarcoma CDH10 1008 cadherin 10, type 2 (T2-cadherin) 5p14.2 5187 1749 604555 NP_006718 "NM_006727;NM_001190450" ENSP00000264463 candidate 0 0 0 Eukaryotes 7 0 Cell motility and interactions 79 chr5 24487775 24593599 WES head and neck squamous cell carcinoma,lung,pancreas CDH11 1009 cadherin 11, type 2, OB-cadherin (osteoblast) 16q21 8960 1750 600023 NP_001788 NM_001797 - known 1 0 0 Eukaryotes 4 4 Cell motility and interactions,Development 82 chr16 64981509 65038772 CGC bone cyst CDH12 1010 cadherin 12, type 2 (N-cadherin 2) 5p14.3 11081 1751 600562 NP_004052 NM_004061 ENSP00000371689 candidate 0 0 0 Eukaryotes 3 3 Cell motility and interactions 20 chr5 21751849 22078785 WES head and neck squamous cell carcinoma CDH20 28316 cadherin 20, type 2 18q21.33 10429 1760 605807 NP_114097 NM_031891 ENSP00000444767 candidate 0 0 0 Eukaryotes 18 2 Cell motility and interactions 1 chr18 59157787 59221925 WES breast CDH23 64072 cadherin-related 23 10q22.1 5699 13733 605516 "NP_001165406;NP_071407;NP_001165402;NP_443068;NP_001165405;NP_001165407;NP_001165403;NP_001165404;NP_001165401" "NM_001171935;NM_022124;NM_001171931;NM_052836;NM_001171934;NM_001171936;NM_001171932;NM_001171933;NM_001171930" "ENSP00000299366;ENSP00000381768;ENSP00000224721;ENSP00000381789" candidate 0 0 0 Last Universal Common Ancestor 3 0 Cell motility and interactions,Cell response to stimuli,Multicellular activities,Regulation of intracellular processes and metabolism -1 chr10 73199589 73575032 WES chronic lymphocytic leukemia CDH24 64403 cadherin 24, type 2 14q11.2 13019 14265 - "NP_071923;NP_659422" "NM_022478;NM_144985" "ENSP00000380517;ENSP00000434821" candidate 0 0 0 Eukaryotes 4 0 Cell motility and interactions -1 chr14 23517192 23524942 WGS acute myeloid leukemia CDH9 1007 cadherin 9, type 2 (T1-cadherin) 5p14 13021 1768 609974 NP_057363 NM_016279 ENSP00000231021 candidate 0 0 1 Eukaryotes 7 1 Cell motility and interactions 22 chr5 26881248 26988440 WES,WGS chronic lymphocytic leukemia CDHR2 54825 cadherin-related family member 2 5q35.2 15103 18231 - "NP_001165447;NP_060145" "NM_001171976;NM_017675" "ENSP00000424565;ENSP00000261944" candidate 0 0 0 Eukaryotes 5 1 Cell cycle,Cell motility and interactions,Regulation of intracellular processes and metabolism 66 chr5 175992354 176022670 WGS acute myeloid leukemia CDK12 51755 cyclin-dependent kinase 12 17q12 10849 24224 - "NP_055898;NP_057591" "NM_015083;NM_016507" ENSP00000398880 known 0 1 0 Last Universal Common Ancestor 42 0 Cellular metabolism,Cellular processes 70 chr17 37618325 37687566 CGC,HTMS,WES ovarian,breast,lung,pancreas,prostate CDK4 1019 cyclin-dependent kinase 4 12q14 447 1773 123829 NP_000066 "NM_000075;NM_052984" - known 1 0 0 Last Universal Common Ancestor 150 13 Cell cycle,Cellular metabolism,Cellular processes,Regulation of intracellular processes and metabolism,Regulation of transcription 107 chr12 58142311 58145500 CGC,WES,Amplified glioblastoma CDK6 1021 cyclin-dependent kinase 6 7q21-q22 4533 1777 603368 "NP_001138778;NP_001250" "NM_001145306;NM_001259" ENSP00000265734 known 1 0 0 Last Universal Common Ancestor 108 28 Cell cycle,Cell motility and interactions,Cellular metabolism,Cellular processes,Development,Multicellular activities,Regulation of intracellular processes and metabolism,Regulation of transcription 5 chr7 92244457 92462637 CGC,Amplified leukemia CDKN1B 1027 cyclin-dependent kinase inhibitor 1B (p27, Kip1) 12p13.1-p12 2867 1785 600778 NP_004055 NM_004064 ENSP00000228872 candidate 0 0 0 Metazoans 99 13 Cell cycle,Cell motility and interactions,Cell response to stimuli,Cellular metabolism,Cellular processes,Development,Regulation of intracellular processes and metabolism,Signal transduction 103 chr12 12870774 12871877 WES breast,prostate CDKN2A 1029 cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4) 9p21 2542 1787 600160 "NP_001182061;NP_478104;NP_478102;NP_000068" "NM_058196;NM_001195132;NM_058197;NM_058195;NM_000077" "ENSP00000307101;ENSP00000462950" known 0 1 0 Eukaryotes 177 13 Cell cycle,Cell motility and interactions,Cellular metabolism,Cellular processes,DNA/RNA metabolism and transcription,Development,Immune system response,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction 51 chr9 21968727 21974826 CGC,HTMS,WES melanoma,other,recessive,breast,lung,ovarian,pancreas,prostate,cholangiocarcinoma,glioblastoma,head and neck squamous cell carcinoma,liver CDKN2C 1031 cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) 1p32 4534 1789 603369 "NP_001253;NP_523240" "NM_001262;NM_078626" "ENSP00000379452;ENSP00000360826" known 0 1 0 Last Universal Common Ancestor 35 1 Cell cycle,Cellular metabolism,Development,Regulation of intracellular processes and metabolism,Signal transduction 62 chr1 51436041 51439939 CGC glioma,myeloma CDX2 1045 caudal type homeobox 2 13q12.3 2622 1806 600297 NP_001256 NM_001265 - known 1 0 0 Eukaryotes 16 10 Cellular metabolism,DNA/RNA metabolism and transcription,Development,Regulation of intracellular processes and metabolism,Regulation of transcription 0 chr13 28537255 28543143 CGC leukemia CDYL 9425 chromodomain protein, Y-like 6p25.1 4803 1811 603778 "NP_001137442;NP_004815;NP_001137443" "NM_001143970;NM_170752;NM_004824;NR_026590;NM_001143971" "ENSP00000340908;ENSP00000330512" candidate 0 0 1 Last Universal Common Ancestor 27 0 Cellular metabolism,DNA/RNA metabolism and transcription,Development,Multicellular activities,Regulation of intracellular processes and metabolism,Regulation of transcription 24 chr6 4891947 4954287 WES lung CEBPA 1050 CCAAT/enhancer binding protein (C/EBP), alpha 19q13.1 296 1833 116897 NP_004355 NM_004364 ENSP00000427514 known 1 0 0 - 96 7 Cellular metabolism,DNA/RNA metabolism and transcription,Development,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction 69 chr19 33792247 33793320 CGC leukemia,myelodysplasia CELA3A 10136 chymotrypsin-like elastase family, member 3A 1p36.12 6497 15944 - NP_005738 NM_005747 ENSP00000290122 candidate 0 0 1 Last Universal Common Ancestor 0 0 Cellular metabolism 55 chr1 22328168 22336350 WGS chronic lymphocytic leukemia CELF4 56853 CUGBP, Elav-like family member 4 18q12 12534 14015 612679 "NP_064565;NP_001020258;NP_001020260;NP_001020259" "NM_020180;NM_001025087;NM_001025089;NM_001025088" "ENSP00000406823;ENSP00000410584;ENSP00000335631" candidate 0 0 0 Eukaryotes 2 1 Cell cycle,Development -1 chr18 34833777 35145604 WES chronic lymphocytic leukemia CEP152 22995 centrosomal protein 152kDa 15q21.1 16778 29298 613529 "NP_001181927;NP_055800" "NM_001194998;NM_014985" "ENSP00000370337;ENSP00000382271" candidate 0 0 0 Metazoans 2 1 -1 23 chr15 49030449 49097846 WGS lung CEP170 9859 centrosomal protein 170kDa 1q44 17172 28920 613023 "NP_001035864;NP_001035863;NP_055627" "NM_001042405;NM_001042404;NM_014812" "ENSP00000355502;ENSP00000355501;ENSP00000355500" candidate 0 0 1 Eukaryotes 19 0 -1 91 chr1 243289754 243388582 WGS acute myeloid leukemia,chronic lymphocytic leukemia,prostate CFHR2 3080 complement factor H-related 2 1q31.3 2933 4890 600889 NP_005657 NM_005666 ENSP00000356385 candidate 0 0 1 Vertebrates 0 1 -1 83 chr1 196913011 196928207 WES melanoma CFP 5199 complement factor properdin Xp11.4 2308 8864 300383 "NP_001138724;NP_002612" "NM_001145252;NM_002621" "ENSP00000380189;ENSP00000247153" candidate 0 0 0 Eukaryotes 4 1 Cell response to stimuli,Cellular metabolism,Immune system response 6 chrX 47483677 47489243 WES breast CHCHD7 79145 coiled-coil-helix-coiled-coil-helix domain containing 7 8q12.1 13048 28314 611238 "NP_077276;NP_001011669;NP_001011670;NP_001011668;NP_001011667;NP_001011671" "NM_024300;NM_001011669;NM_001011670;NM_001011668;NM_001011667;NM_001011671" "ENSP00000306425;ENSP00000428274;ENSP00000347469;ENSP00000428917" known 1 0 0 Eukaryotes 0 3 -1 38 chr8 57125410 57129991 CGC salivary CHD1 1105 chromodomain helicase DNA binding protein 1 5q15-q21 3668 1915 602118 NP_001261 NM_001270 ENSP00000284049 candidate 0 0 0 Last Universal Common Ancestor 22 4 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription 67 chr5 98192087 98262090 WGS prostate CHD1L 9557 chromodomain helicase DNA binding protein 1-like 1q12 9880 1916 613039 "NP_004275;NP_078844;NP_001243266;NP_001243265;NP_001243267" "NM_004284;NM_024568;NM_001256337;NR_046070;NM_001256336;NM_001256338" "ENSP00000355100;ENSP00000358263;ENSP00000358262" known 0 0 0 Last Universal Common Ancestor 36 0 -1 109 chr1 146714354 146767187 CGC,Amplified CHD2 1106 chromodomain helicase DNA binding protein 2 15q26 3669 1917 602119 "NP_001262;NP_001036037" "NM_001271;NM_001042572" "ENSP00000406581;ENSP00000377747" candidate 0 0 0 Last Universal Common Ancestor 4 0 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription 49 chr15 93444468 93567932 WES chronic lymphocytic leukemia CHD3 1107 chromodomain helicase DNA binding protein 3 17p13.1 9071 1918 602120 "NP_001005273;NP_001005271;NP_005843" "NM_001005273;NM_001005271;NM_005852" "ENSP00000369716;ENSP00000332628;ENSP00000350907" candidate 0 0 0 Last Universal Common Ancestor 188 1 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription 78 chr17 7788125 7814900 WGS breast CHD4 1108 chromodomain helicase DNA binding protein 4 12p13 4472 1919 603277 NP_001264 NM_001273 ENSP00000349508 candidate 0 0 0 Last Universal Common Ancestor 94 4 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription 109 chr12 6680032 6715539 WES endometrium CHD5 450091 Coronary heart disease, susceptibility to, 5 - - - 608901 - - - candidate 0 0 -1 Last Universal Common Ancestor 0 0 -1 -1 - 0 0 WES,WGS breast,prostate CHD6 84181 chromodomain helicase DNA binding protein 6 20q12 13049 19057 - NP_115597 NM_032221 ENSP00000362330 candidate 0 0 0 Last Universal Common Ancestor 11 1 Cellular metabolism,DNA/RNA metabolism and transcription,Development,Regulation of intracellular processes and metabolism,Regulation of transcription -1 chr20 40033236 40162212 WES bladder CHD7 55636 chromodomain helicase DNA binding protein 7 8q12.2 10595 20626 608892 NP_060250 NM_017780 ENSP00000392028 candidate 0 0 0 Last Universal Common Ancestor 34 3 Cell cycle,Cell response to stimuli,Cellular metabolism,DNA/RNA metabolism and transcription,Development,Multicellular activities,Regulation of intracellular processes and metabolism,Regulation of transcription 86 chr8 61653992 61778489 WGS medulloblastoma CHEK2 11200 checkpoint kinase 2 22q11|22q12.1 5084 16627 604373 "NP_001005735;NP_009125;NP_665861" "NM_001005735;NM_007194;NM_145862" "ENSP00000372023;ENSP00000329178;ENSP00000329012" known 0 1 0 Last Universal Common Ancestor 70 0 Cell cycle,Cellular metabolism,Cellular processes,Development,Regulation of intracellular processes and metabolism,Signal transduction 35 chr22 29083888 29130709 CGC CHGA 1113 chromogranin A (parathyroid secretory protein 1) 14q32 7170 1929 118910 NP_001266 NM_001275 ENSP00000216492 candidate 0 0 0 Opisthokonts 7 0 Multicellular activities 59 chr14 93389705 93401226 WES melanoma CHGB 1114 chromogranin B (secretogranin 1) 20pter-p12 7512 1930 118920 NP_001810 NM_001819 ENSP00000368244 candidate 0 0 0 Metazoans 40 1 -1 65 chr20 5892280 5905692 WGS breast CHIC2 26511 cysteine-rich hydrophobic domain 2 4q11 10373 1935 604332 NP_036242 NM_012110 ENSP00000263921 known 1 0 0 Metazoans 9 4 -1 77 chr4 54876265 54930467 CGC leukemia CHL1 10752 cell adhesion molecule with homology to L1CAM (close homolog of L1) 3p26.1 7598 1939 607416 "NP_001240317;NP_001240316;NP_006605" "NM_001253388;NM_001253387;NR_045572;NM_006614" ENSP00000256509 candidate 0 0 0 Last Universal Common Ancestor 4 5 Cell cycle,Cell motility and interactions,Development,Signal transduction 43 chr3 361460 447391 WES colorectal CHMP2B 25978 charged multivesicular body protein 2B 3p11.2 13174 24537 609512 "NP_001231573;NP_054762" "NM_001244644;NM_014043" ENSP00000263780 candidate 0 0 0 Eukaryotes 18 3 Cellular processes 88 chr3 87289848 87302969 WES melanoma CHMP4A 29082 charged multivesicular body protein 4A 14q12 16597 20274 610051 NP_054888 NM_014169 ENSP00000324205 candidate 0 0 0 Eukaryotes 24 0 Cellular processes 73 chr14 24679086 24682774 WGS glioblastoma CHN1 1123 chimerin (chimaerin) 1 2q31.1 319 1943 118423 "NP_001020372;NP_001813;NP_001193531" "NM_001025201;NM_001822;NM_001206602;NR_038133" "ENSP00000295497;ENSP00000386741" known 1 0 0 Eukaryotes 12 0 Signal transduction 39 chr2 175664847 175809669 CGC sarcoma CHRNA9 55584 cholinergic receptor, nicotinic, alpha 9 4p14 16092 14079 605116 NP_060051 NM_017581 ENSP00000312663 candidate 0 0 0 Metazoans 0 1 Cellular processes 51 chr4 40337485 40356534 WGS breast CHST1 8534 carbohydrate (keratan sulfate Gal-6) sulfotransferase 1 11p11.2 7051 1969 603797 NP_003645 NM_003654 - candidate 0 0 0 Metazoans 27 0 Cellular metabolism,Immune system response 68 chr11 45671241 45672473 WES melanoma CHST7 56548 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 7 Xp11.23 2302 13817 300375 NP_063939 NM_019886 ENSP00000276055 candidate 0 0 0 Vertebrates 1 1 Cellular metabolism 3 chrX 46433367 46434824 WGS breast CIC 23152 capicua homolog (Drosophila) 19q13.2 10831 14214 612082 NP_055940 NM_015125 ENSP00000160740 known 0 1 0 Last Universal Common Ancestor 25 0 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription 91 chr19 42788857 42799340 CGC,WES oligodendroglioma,breast CIITA 4261 class II, major histocompatibility complex, transactivator 16p13 2475 7067 600005 NP_000237 NM_000246 - known 1 0 0 Last Universal Common Ancestor 26 1 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription 48 chr16 10971188 11017157 CGC,WES lymphoma,non-hodgkin lymphoma CIT 11113 citron (rho-interacting, serine/threonine kinase 21) 12q24 9289 1985 605629 "NP_001193928;NP_009105" "NM_001206999;NM_007174" "ENSP00000376306;ENSP00000261833" candidate 0 0 0 Last Universal Common Ancestor 1 2 Cell cycle,Cellular metabolism,Cellular processes,Development,Signal transduction 80 chr12 120127953 120313972 WES lung CKS1B 1163 CDC28 protein kinase regulatory subunit 1B 1q21.2 299 19083 116900 NP_001817 "NM_001826;NR_024163" ENSP00000311083 known 0 0 8 Eukaryotes 30 0 Cell cycle,Regulation of intracellular processes and metabolism,Signal transduction 88 chr5 61808073 61808309 CGC,Amplified CLCC1 23155 chloride channel CLIC-like 1 1p13.3 17471 29675 - "NP_055942;NP_001041675" "NM_015127;NM_001048210" "ENSP00000358988;ENSP00000411591" candidate 0 0 0 Metazoans 2 0 -1 86 chr1 109477295 109493059 WGS liver CLCN3 1182 chloride channel 3 4q33 2785 2021 600580 "NP_001820;NP_001230303;NP_776297;NP_001230301" "NM_001829;NM_001243374;NM_173872;NM_001243372" ENSP00000424603 candidate 0 0 0 Last Universal Common Ancestor 5 4 Cellular processes,Regulation of intracellular processes and metabolism 103 chr4 170557080 170641213 WES breast CLCN4 1183 chloride channel 4 Xp22.3 2362 2022 302910 NP_001821 NM_001830 ENSP00000370213 candidate 0 0 2 Last Universal Common Ancestor 0 0 Cellular processes 49 chrX 10153073 10201621 WES pancreas CLCN5 1184 chloride channel 5 Xp11.23-p11.22 2053 2023 300008 "NP_000075;NP_001121371;NP_001121370" "NM_000084;NM_001127899;NM_001127898" ENSP00000365256 candidate 0 0 2 Last Universal Common Ancestor 0 1 Cellular processes 63 chrX 49806924 49856873 WGS prostate CLDN1 9076 claudin 1 3q28-q29 4760 2032 603718 NP_066924 NM_021101 ENSP00000295522 candidate 0 0 0 Vertebrates 17 3 Cell motility and interactions 32 chr3 190026069 190039995 WGS lung CLDN5 7122 claudin 5 22q11.21 3654 2047 602101 "NP_003268;NP_001124333" "NM_003277;NM_001130861" "ENSP00000384554;ENSP00000400612" candidate 0 0 0 Vertebrates 18 2 Cell motility and interactions 64 chr22 19511125 19512033 WGS glioblastoma CLEC19A 728276 C-type lectin domain family 19, member A 16p12.3 - 34522 - - NR_024436 - candidate 0 0 -1 Eukaryotes 0 0 -1 -1 - 0 0 WES breast CLIP1 6249 CAP-GLY domain containing linker protein 1 12q24.3 1568 10461 179838 "NP_001234926;NP_937883;NP_002947" "NM_001247997;NM_198240;NM_002956" "ENSP00000351665;ENSP00000445531" candidate 0 0 0 Eukaryotes 8 5 Cell cycle 86 chr12 122757425 122864999 WES pancreas CLN8 2055 ceroid-lipofuscinosis, neuronal 8 (epilepsy, progressive with mental retardation) 8p23 6383 2079 607837 NP_061764 "NM_001034061;NM_018941" ENSP00000328182 candidate 0 0 0 Eukaryotes 0 0 Cell cycle,Cell response to stimuli,Cellular metabolism,Cellular processes,Development,Multicellular activities,Regulation of intracellular processes and metabolism 52 chr8 1719221 1728730 WGS chronic lymphocytic leukemia CLP1 10978 CLP1, cleavage and polyadenylation factor I subunit, homolog (S. cerevisiae) 11q12 16382 16999 608757 "NP_006822;NP_001136069" "NM_006831;NM_001142597" ENSP00000304704 known 1 0 0 Eukaryotes 0 1 DNA/RNA metabolism and transcription,Regulation of transcription 101 chr11 57426949 57428905 CGC leukemia CLSPN 63967 claspin 1p34.2 9257 19715 605434 "NP_071394;NP_001177410" "NM_022111;NM_001190481" - candidate 0 0 0 Metazoans 26 6 Cellular metabolism,DNA/RNA metabolism and transcription 4 chr1 36202100 36230927 WGS prostate CLSTN2 64084 calsyntenin 2 3q23 13077 17448 611323 NP_071414 NM_022131 ENSP00000402460 candidate 0 0 0 Metazoans 0 1 Cell motility and interactions 22 chr3 139654217 140285092 WES colorectal,head and neck squamous cell carcinoma CLTC 1213 clathrin, heavy chain (Hc) 17q11-qter 350 2092 118955 NP_004850 NM_004859 ENSP00000269122 known 1 0 1 Eukaryotes 153 3 Cellular processes 109 chr17 57721637 57771210 CGC kidney,lymphoma CLTCL1 8218 clathrin, heavy chain-like 1 22q11.2|22q11.21 3172 2093 601273 "NP_009029;NP_001826" "NM_007098;NM_001835" "ENSP00000439662;ENSP00000445677" known 1 0 1 Eukaryotes 10 0 Cellular processes 32 chr22 19168245 19279164 CGC,WGS lymphoma,glioblastoma CMKLR1 1240 chemokine-like receptor 1 12q24.1 3829 2121 602351 "NP_001135817;NP_004063;NP_001135815;NP_001135816" "NM_001142345;NM_004072;NM_001142343;NM_001142344" "ENSP00000311733;ENSP00000401293" candidate 0 0 0 Vertebrates 0 0 Cell motility and interactions,Development,Signal transduction 47 chr12 108685621 108686736 HTMS breast,lung,ovarian,pancreas,prostate CMYA5 202333 cardiomyopathy associated 5 5q14.1 16728 14305 612193 NP_705838 NM_153610 ENSP00000394770 candidate 0 0 0 Last Universal Common Ancestor 15 0 -1 -1 chr5 78985731 79095436 WGS lung CNBP 7555 CCHC-type zinc finger, nucleic acid binding protein 3q21 311 13164 116955 "NP_001120668;NP_001120665;NP_003409;NP_001120667;NP_001120664;NP_001120666" "NM_001127196;NM_001127193;NM_003418;NM_001127195;NM_001127192;NM_001127194" - known 1 0 0 Eukaryotes 71 0 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription 109 chr3 128889299 128890600 CGC bone cyst CNDP2 55748 CNDP dipeptidase 2 (metallopeptidase M20 family) 18q22.3 9893 24437 169800 "NP_060705;NP_001161971" "NM_018235;NM_001168499" - candidate 0 0 0 Last Universal Common Ancestor 5 5 Cellular metabolism 105 chr18 72167209 72187300 WGS melanoma CNGB1 1258 cyclic nucleotide gated channel beta 1 16q13 7204 2151 600724 "NP_001288;NP_001129111" "NM_001297;NM_001135639" ENSP00000311670 candidate 0 0 0 Eukaryotes 0 1 Cell response to stimuli,Cellular processes 22 chr16 57918071 58001190 WGS prostate CNNM4 26504 cyclin M4 2q11 7420 105 607805 NP_064569 NM_020184 ENSP00000366275 candidate 0 0 0 Last Universal Common Ancestor 0 1 Cellular processes 21 chr2 97426737 97475251 WES breast CNOT1 23019 CCR4-NOT transcription complex, subunit 1 16q21 11999 7877 604917 "NP_057368;NP_996882" "NM_016284;NM_206999" "ENSP00000455635;ENSP00000320949;ENSP00000413113" candidate 0 0 0 Eukaryotes 28 0 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription 109 chr16 58554865 58633241 WGS prostate CNOT3 4849 CCR4-NOT transcription complex, subunit 3 19q13.4 5368 7879 604910 NP_055331 NM_014516 ENSP00000221232 candidate 0 0 0 Eukaryotes 17 0 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription 68 chr19 54646854 54659142 WES,WGS chronic lymphocytic leukemia CNRIP1 25927 cannabinoid receptor interacting protein 1 2p14 12813 24546 - "NP_056278;NP_001104571" "NM_015463;NM_001111101" ENSP00000263655 candidate 0 0 0 Metazoans 2 0 -1 -1 chr2 68520997 68546532 WGS liver CNTN1 1272 contactin 1 12q11-q12 7189 2171 600016 "NP_001834;NP_001242992;NP_778203;NP_001242993" "NM_001843;NM_001256063;NM_175038;NM_001256064" "ENSP00000448004;ENSP00000448653;ENSP00000447006" candidate 0 0 0 Eukaryotes 2 0 Signal transduction 62 chr12 41302235 41463834 WES gastric CNTN2 6900 contactin 2 (axonal) 1q32.1 1826 2172 190197 NP_005067 NM_005076 ENSP00000330633 candidate 0 0 0 Eukaryotes 37 0 Cell cycle,Cell motility and interactions,Development 21 chr1 205022314 205042890 WES acute myeloid leukemia CNTN3 5067 contactin 3 (plasmacytoma associated) 3p12.3 - 2173 601325 NP_065923 NM_020872 ENSP00000263665 candidate 0 0 0 Metazoans 1 0 -1 -1 chr3 74313555 74570263 WES breast CNTN4 152330 contactin 4 3p26.3 16239 2174 607280 "NP_783200;NP_001193884;NP_783302;NP_001193885" "NM_175612;NM_175607;NM_001206955;NM_175613;NM_001206956" "ENSP00000380602;ENSP00000396010" candidate 0 0 0 Metazoans 2 0 Cell cycle,Cell motility and interactions,Development,Multicellular activities,Regulation of intracellular processes and metabolism -1 chr3 2613188 3097901 WES colorectal CNTN5 53942 contactin 5 11q21-q22.2 6241 2175 607219 "NP_780775;NP_055176;NP_001230200;NP_001230199" "NM_175566;NM_014361;NM_001243271;NM_001243270" "ENSP00000433575;ENSP00000435637" candidate 0 0 0 Eukaryotes 70 0 -1 9 chr11 99426946 100226948 WES,WGS pancreas,melanoma CNTN6 27255 contactin 6 3p26-p25 6242 2176 607220 NP_055276 NM_014461 ENSP00000442791 candidate 0 0 0 Eukaryotes 14 0 Development,Signal transduction 15 chr3 1189693 1445099 WES breast CNTNAP1 8506 contactin associated protein 1 17q21 3825 8011 602346 NP_003623 NM_003632 ENSP00000264638 candidate 0 0 0 Eukaryotes 16 1 Cell motility and interactions,Regulation of intracellular processes and metabolism,Signal transduction 80 chr17 40834848 40850925 WES pancreas CNTNAP2 26047 contactin associated protein-like 2 7q35 5197 13830 604569 NP_054860 NM_014141 ENSP00000354778 candidate 0 0 0 Eukaryotes 4 2 Multicellular activities,Signal transduction 52 chr7 146471359 148112705 WES head and neck squamous cell carcinoma,lung,pancreas CNTRL 11064 centriolin 9q33.2 5691 1858 605496 NP_008949 NM_007018 ENSP00000238341 known 1 0 0 Opisthokonts 7 2 -1 35 chr9 123850605 123937502 CGC myeloma,non-hodgkin lymphoma COL11A1 1301 collagen, type XI, alpha 1 1p21 375 2186 120280 "NP_542197;NP_542196;NP_001845;NP_001177638" "NM_080630;NM_080629;NM_001854;NM_001190709" "ENSP00000302551;ENSP00000359114;ENSP00000351163" candidate 0 0 0 Last Universal Common Ancestor 3 1 Cell motility and interactions,Cell response to stimuli,Cellular processes,Development 31 chr1 103343578 103573734 WES breast,lung COL11A2 1302 collagen, type XI, alpha 2 6p21.3 9049 2187 120290 "NP_542410;NP_542411;NP_001157243;NP_542412" "NM_080679;NM_080680;NM_001163771;NM_080681" "ENSP00000378620;ENSP00000355123;ENSP00000339915;ENSP00000363840" candidate 0 0 0 Last Universal Common Ancestor 9 0 Cell motility and interactions,Cell response to stimuli,Cellular processes,Development 88 chr6 33131458 33160017 WGS prostate COL17A1 1308 collagen, type XVII, alpha 1 10q24.3 223 2194 113811 NP_000485 "NM_000494;NM_130778" ENSP00000340937 candidate 0 0 0 Eukaryotes 8 3 Cell motility and interactions,Cellular processes,Development 15 chr10 105791996 105840431 WGS glioblastoma COL19A1 1310 collagen, type XIX, alpha 1 6q12-q13 364 2196 120165 NP_001849 NM_001858 - candidate 0 0 0 Eukaryotes 1 0 Cell motility and interactions,Cellular processes,Development 10 chr6 70589460 70916975 WES breast COL1A1 1277 collagen, type I, alpha 1 17q21.33 362 2197 120150 NP_000079 NM_000088 ENSP00000225964 known 1 0 0 Last Universal Common Ancestor 3 9 Cell response to stimuli,Cellular processes,Development 87 chr17 48262866 48278874 CGC,WGS bone cyst,sarcoma,breast COL1A2 1278 collagen, type I, alpha 2 7q22.1 363 2198 120160 NP_000080 NM_000089 ENSP00000297268 candidate 0 0 0 Last Universal Common Ancestor 22 2 Cell response to stimuli,Cellular processes,Development,Signal transduction 97 chr7 94024344 94059702 WES head and neck squamous cell carcinoma COL22A1 169044 collagen, type XXII, alpha 1 8q24.3 9885 22989 610026 NP_690848 NM_152888 ENSP00000303153 candidate 0 0 0 Last Universal Common Ancestor 1 0 -1 -1 chr8 139601499 139895415 WES head and neck squamous cell carcinoma,lung COL25A1 84570 collagen, type XXV, alpha 1 4q25 9886 18603 610004 "NP_115907;NP_942014;NP_001243003" "NR_045756;NM_032518;NM_198721;NM_001256074" "ENSP00000382078;ENSP00000382077" candidate 0 0 0 Last Universal Common Ancestor 3 0 Cellular processes -1 chr4 109740408 110223175 WES chronic lymphocytic leukemia COL3A1 1281 collagen, type III, alpha 1 2q31 365 2201 120180 NP_000081 NM_000090 ENSP00000304408 candidate 0 0 0 Last Universal Common Ancestor 12 4 Cell motility and interactions,Cell response to stimuli,Cellular metabolism,Cellular processes,Development,Immune system response,Multicellular activities,Regulation of transcription,Signal transduction 89 chr2 189839216 189876497 WES colorectal,glioblastoma COL4A2 1284 collagen, type IV, alpha 2 13q34 355 2203 120090 NP_001837 NM_001846 ENSP00000353654 candidate 0 0 0 Last Universal Common Ancestor 32 4 Cell motility and interactions,Cellular processes,Development 95 chr13 110960251 111164535 WES lung COL5A1 1289 collagen, type V, alpha 1 9q34.2-q34.3 368 2209 120215 NP_000084 NM_000093 ENSP00000360882 candidate 0 0 0 Last Universal Common Ancestor 13 1 Cellular processes 65 chr9 137534034 137734146 WES,WGS pancreas,prostate COL7A1 1294 collagen, type VII, alpha 1 3p21.1 358 2214 120120 NP_000085 NM_000094 ENSP00000332371 candidate 0 0 0 Last Universal Common Ancestor 6 0 Cellular processes,Development 55 chr3 48602214 48632592 WES breast COPS3 8533 COP9 constitutive photomorphogenic homolog subunit 3 (Arabidopsis) 17p11.2 7262 2239 604665 "NP_003644;NP_001186054" "NM_003653;NM_001199125" "ENSP00000437606;ENSP00000268717" known 0 0 0 Eukaryotes 72 3 Cell response to stimuli,Development,Signal transduction 98 chr17 17150415 17184500 CGC,Amplified COPS7B 64708 COP9 constitutive photomorphogenic homolog subunit 7B (Arabidopsis) 2q37.1 9889 16760 - NP_073567 NM_022730 ENSP00000386880 candidate 0 0 0 Eukaryotes 27 4 -1 30 chr2 232653281 232672352 WGS liver COX6C 1345 cytochrome c oxidase subunit VIc 8q22.2 494 2285 124090 NP_004365 NM_004374 ENSP00000428895 known 1 0 3 Metazoans 7 0 -1 109 chr8 100899736 100904249 CGC uterus CPAMD8 27151 C3 and PZP-like, alpha-2-macroglobulin domain containing 8 19p13.11 9892 23228 608841 NP_056507 NM_015692 ENSP00000402505 candidate 0 0 0 Metazoans 7 1 -1 -1 chr19 17003922 17137593 WES breast,colorectal CPD 1362 carboxypeptidase D 17q11.2 4375 2301 603102 "NP_001295;NP_001186704" "NM_001304;NM_001199775" ENSP00000225719 candidate 0 0 0 Last Universal Common Ancestor 1 5 Cellular metabolism 98 chr17 28705999 28791829 WGS liver CPS1 1373 carbamoyl-phosphate synthase 1, mitochondrial 2q35 1995 2323 608307 "NP_001866;NP_001116106;NP_001116105" "NM_001875;NM_001122634;NM_001122633" "ENSP00000402608;ENSP00000406136;ENSP00000233072" candidate 0 0 0 Last Universal Common Ancestor 22 0 Cellular metabolism 71 chr2 211421443 211542706 WES lymphoma CPVL 54504 carboxypeptidase, vitellogenic-like 7p15.1 7479 14399 609780 "NP_112601;NP_061902" "NM_031311;NM_019029" "ENSP00000379572;ENSP00000265394" candidate 0 0 0 Last Universal Common Ancestor 7 0 Cellular metabolism 50 chr7 29035391 29160677 WGS prostate CR1 1378 complement component (3b/4b) receptor 1 (Knops blood group) 1q32 398 2334 120620 "NP_000642;NP_000564" "NM_000651;NM_000573" ENSP00000383744 candidate 0 0 1 Last Universal Common Ancestor 1 0 Cell response to stimuli,Cellular metabolism,Immune system response 82 chr1 207669613 207803973 WGS prostate CREB1 1385 cAMP responsive element binding protein 1 2q34 442 2345 123810 "NP_604391;NP_004370" "NM_134442;NM_004379" - known 1 0 0 Metazoans 33 5 Cellular metabolism,Cellular processes,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction 90 chr2 208420360 208461779 CGC histiocytoma,sarcoma CREB3L1 90993 cAMP responsive element binding protein 3-like 1 11p11.2 16751 18856 - NP_443086 NM_052854 ENSP00000434939 known 1 0 0 Eukaryotes 4 0 Cell response to stimuli,Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription 59 chr11 46299663 46342080 CGC sarcoma CREB3L2 64764 cAMP responsive element binding protein 3-like 2 7q34 16391 23720 608834 "NP_001240704;NP_919047" "NM_001253775;NM_194071" "ENSP00000410314;ENSP00000329140" known 1 0 0 Eukaryotes 12 5 Cell response to stimuli,Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription 104 chr7 137565225 137686451 CGC sarcoma CREBBP 1387 CREB binding protein 16p13.3 2534 2348 600140 "NP_004371;NP_001073315" "NM_004380;NM_001079846" ENSP00000262367 known 1 1 0 Eukaryotes 364 1 Cellular metabolism,Cellular processes,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction 97 chr16 3777722 3929917 CGC,WES leukemia,lymphoma,non-hodgkin lymphoma,bladder CREM 1390 cAMP responsive element modulator 10p11.21 444 2352 123812 "NP_898831;NP_877571;NP_898883;NP_874392;NP_877572;NP_898829;NP_001872;NP_874386;NP_874390;NP_874388;NP_874393;NP_853549;NP_874391;NP_878273;NP_874387;NP_877570;NP_877573;NP_874389;NP_878270;NP_898830;NP_874394" "NM_183013;NM_182770;NM_183060;NM_182723;NM_182771;NM_183011;NM_001881;NM_182717;NM_182721;NM_182719;NM_182724;NM_181571;NM_182722;NM_182853;NM_182718;NM_182769;NM_182772;NM_182720;NM_182850;NM_183012;NM_182725" "ENSP00000363858;ENSP00000265372;ENSP00000349387;ENSP00000354593;ENSP00000333055;ENSP00000409220;ENSP00000363860" candidate 0 0 0 Metazoans 34 0 Cellular metabolism,DNA/RNA metabolism and transcription,Development,Multicellular activities,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction 90 chr10 35426764 35500728 WGS liver CRIPAK 285464 cysteine-rich PAK1 inhibitor 4p16.3 8753 26619 610203 NP_787114 NM_175918 ENSP00000323978 candidate 0 0 5 Eukaryotes 4 0 Cell response to stimuli,Cellular processes,Regulation of intracellular processes and metabolism,Signal transduction -1 chr4 1388300 1389637 WGS lymphoma CRLF2 64109 cytokine receptor-like factor 2 "Xp22.3; Yp11.3" 2288 14281 400023 "NP_001012288;NP_071431" "NM_001012288;NM_022148" ENSP00000370979 known 1 0 1 Vertebrates 3 0 -1 25 chrX 1314893 1331527 CGC leukemia CROCC 9696 ciliary rootlet coiled-coil, rootletin 1p36.13 16758 21299 - NP_055490 NM_014675 ENSP00000364691 candidate 0 0 1 Last Universal Common Ancestor 3 0 Cellular processes,Development 45 chr1 17248514 17298938 WGS lymphoma CRTC1 23373 CREB regulated transcription coactivator 1 19p13.11 6339 16062 607536 "NP_001091952;NP_056136" "NM_001098482;NM_015321;NM_025021" ENSP00000345001 known 1 0 1 Metazoans 3 0 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription 58 chr19 18794513 18888189 CGC salivary CRTC3 64784 CREB regulated transcription coactivator 3 15q26.1 13384 26148 608986 "NP_073606;NP_001036039" "NM_022769;NM_001042574" ENSP00000416573 known 1 0 0 Metazoans 8 6 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription 109 chr15 91073304 91185369 CGC salivary CRYBB3 1417 crystallin, beta B3 22q11.2-q12.1|22q11.23 431 2400 123630 NP_004067 NM_004076 ENSP00000215855 candidate 0 0 0 Last Universal Common Ancestor 5 0 Cell response to stimuli 0 chr22 25597364 25603176 WGS lung CSH1 1442 chorionic somatomammotropin hormone 1 (placental lactogen) 17q24.2 8350 2440 150200 NP_001308 "NM_001317;NM_022641;NM_022640" ENSP00000316416 candidate 0 0 3 Vertebrates 6 0 Signal transduction 9 chr17 61972385 61973599 WES melanoma CSMD1 64478 CUB and Sushi multiple domains 1 8p23.2 10523 14026 608397 NP_150094 NM_033225 ENSP00000334828 candidate 0 0 0 Last Universal Common Ancestor 13 0 -1 -1 chr8 2796110 4851938 WGS breast CSMD2 114784 CUB and Sushi multiple domains 2 1p34.3 13094 19290 608398 NP_443128 NM_052896 ENSP00000241312 candidate 0 0 0 Last Universal Common Ancestor 6 0 -1 -1 chr1 33985121 34631414 WES acute myeloid leukemia CSMD3 114788 CUB and Sushi multiple domains 3 8q23.3 16329 19291 608399 "NP_443132;NP_937756;NP_937757" "NM_052900;NM_198123;NM_198124" "ENSP00000412263;ENSP00000297405;ENSP00000345799" candidate 0 0 0 Last Universal Common Ancestor 1 0 -1 -1 chr8 113237003 114449083 WES chronic lymphocytic leukemia,colorectal,gastric,head and neck squamous cell carcinoma,kidney,liver CSNK2B 1460 casein kinase 2, beta polypeptide 6p21-p12|6p21.3 278 2460 115441 NP_001311 NM_001320 ENSP00000365042 candidate 0 0 0 Eukaryotes 302 0 Signal transduction 36 chr6 31634609 31637700 WES,WGS medulloblastoma,liver CSPP1 79848 centrosome and spindle pole associated protein 1 8q13.2 7991 26193 611654 NP_079066 "NM_001077204;NM_024790" ENSP00000262210 candidate 0 0 0 Eukaryotes 2 0 -1 35 chr8 67976634 68107825 WES breast CTBP2 1488 C-terminal binding protein 2 10q26.13 4016 2495 602619 "NP_001077383;NP_073713;NP_001320" "NM_001083914;NM_022802;NM_001329" ENSP00000338615 candidate 0 0 0 Last Universal Common Ancestor 87 2 Cell cycle,Other,Regulation of intracellular processes and metabolism 106 chr10 126678090 126716328 WGS glioblastoma,lymphoma CTC1 80169 CTS telomere maintenance complex component 1 17p13.1 7980 26169 613129 NP_079375 NM_025099 - candidate 0 0 0 Metazoans 1 0 -1 24 chr17 8131501 8146466 WGS lymphoma CTCF 10664 CCCTC-binding factor (zinc finger protein) 16q21-q22.3 5005 13723 604167 "NP_006556;NP_001177951" "NM_006565;NM_001191022" "ENSP00000384707;ENSP00000264010" candidate 0 0 0 Last Universal Common Ancestor 4 4 Cell cycle,Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription 100 chr16 67644736 67671772 WES breast CTDNEP1 23399 CTD nuclear envelope phosphatase 1 17p13 16845 19085 610684 "NP_001137247;NP_056158" "NM_001143775;NM_015343" "ENSP00000460683;ENSP00000321732" candidate 0 0 2 Eukaryotes 1 3 Cellular processes 104 chr17 7147507 7154615 WES,WGS medulloblastoma CTIF 9811 CBP80/20-dependent translation initiation factor 18q21.1 11083 23925 613178 "NP_001135869;NP_055587" "NM_001142397;NM_014772" ENSP00000256413 candidate 0 0 0 Metazoans 1 0 DNA/RNA metabolism and transcription 52 chr18 46145937 46385927 WES breast CTNNA2 1496 catenin (cadherin-associated protein), alpha 2 2p12-p11.1 228 2510 114025 "NP_004380;NP_001158355" "NM_004389;NM_001164883" ENSP00000419295 candidate 0 0 2 Eukaryotes 5 0 -1 41 chr2 79878683 80874994 WES pancreas CTNNA3 29119 catenin (cadherin-associated protein), alpha 3 10q22.2 9639 2511 607667 "NP_001120856;NP_037398" "NM_001127384;NM_013266" "ENSP00000362849;ENSP00000389714" candidate 0 0 0 Eukaryotes 2 0 -1 17 chr10 67680091 69407271 WGS glioblastoma CTNNB1 1499 catenin (cadherin-associated protein), beta 1, 88kDa 3p21 286 2514 116806 "NP_001091679;NP_001091680;NP_001895" "NM_001098209;NM_001098210;NM_001904" "ENSP00000379488;ENSP00000379486;ENSP00000344456" known 1 0 0 Eukaryotes 369 9 Cell cycle,Cell motility and interactions,Cellular metabolism,Cellular processes,DNA/RNA metabolism and transcription,Development,Multicellular activities,Other,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction 102 chr3 41266016 41280830 CGC,HTMS,WES,WGS colorectal,liver,other,ovarian,salivary,breast,lung,pancreas,prostate,sarcoma,colorectal (non-hypermutated),gastric,medulloblastoma CUL3 8452 cullin 3 2q36.2 9123 2553 603136 NP_003581 NM_003590 "ENSP00000343601;ENSP00000264414" candidate 0 0 0 Eukaryotes 1157 2 Cell cycle,Cellular metabolism,Development,Regulation of intracellular processes and metabolism 103 chr2 225338965 225449726 WGS liver,prostate CUL7 9820 cullin 7 6p21.1 9901 21024 609577 "NP_001161842;NP_055595" "NM_001168370;NM_014780" "ENSP00000438788;ENSP00000265348" candidate 0 0 0 Eukaryotes 24 1 Cellular metabolism,Development 82 chr6 43005429 43021596 WES kidney CUX1 1523 cut-like homeobox 1 7q22.1 295 2557 116896 "NP_001904;NP_001189475;NP_853530;NP_001189474;NP_852477;NP_001189473;NP_001189472" "NM_001913;NM_001202546;NM_181552;NM_001202545;NM_181500;NM_001202544;NM_001202543" "ENSP00000353401;ENSP00000449371;ENSP00000409745;ENSP00000377410;ENSP00000292538;ENSP00000414091;ENSP00000292535" candidate 0 0 0 Opisthokonts 30 1 Cellular metabolism,Cellular processes,DNA/RNA metabolism and transcription,Development,Regulation of intracellular processes and metabolism,Regulation of transcription 96 chr7 101459311 101892319 WES colorectal CXCR6 10663 chemokine (C-X-C motif) receptor 6 3p21 5520 16647 605163 NP_006555 NM_006564 ENSP00000304414 candidate 0 0 0 Vertebrates 0 1 Other,Signal transduction 38 chr3 45987974 45988999 WGS chronic lymphocytic leukemia CXCR7 57007 chemokine (C-X-C motif) receptor 7 2q37.3 9882 23692 610376 NP_064707 "NM_020311;NM_001047841" ENSP00000272928 known 1 0 0 Vertebrates 3 2 Signal transduction 67 chr2 237489109 237490194 CGC lipoma CYB5R4 51167 cytochrome b5 reductase 4 6pter-q22.33 12218 20147 608343 NP_057314 NM_016230 ENSP00000358695 candidate 0 0 0 Last Universal Common Ancestor 0 3 Cell response to stimuli,Cellular metabolism 73 chr6 84569502 84669594 WES breast CYFIP1 23191 cytoplasmic FMR1 interacting protein 1 15q11 5890 13759 606322 "NP_055423;NP_001028200" "NM_014608;NM_001033028" ENSP00000454199 candidate 0 0 1 Eukaryotes 17 1 Cell cycle,Development,Regulation of intracellular processes and metabolism 104 chr15 22925783 23003037 WES,WGS pancreas,liver CYGB 114757 cytoglobin 17q25 6479 16505 608759 NP_599030 NM_134268 ENSP00000293230 candidate 0 0 0 Eukaryotes 2 1 Cellular processes -1 chr17 74527060 74533624 WGS lymphoma CYLD 1540 cylindromatosis (turban tumor syndrome) 16q12.1 5427 2584 605018 "NP_001035877;NP_056062;NP_001035814" "NM_001042412;NM_015247;NM_001042355" "ENSP00000445447;ENSP00000392025" known 0 1 0 Metazoans 49 4 Cell cycle,Cellular metabolism,Regulation of intracellular processes and metabolism,Regulation of transcription 99 chr16 50783610 50830416 CGC cylindroma CYP1A1 1543 cytochrome P450, family 1, subfamily A, polypeptide 1 15q24.1 148 2595 108330 NP_000490 NM_000499 ENSP00000378488 candidate 0 0 1 Last Universal Common Ancestor 1 1 Cellular metabolism 34 chr15 75012833 75015438 WES breast CYP2A 1546 cytochrome P450, family 2, subfamily A 19q13.2 - 2607 - - - - candidate 0 0 -1 Last Universal Common Ancestor 0 0 -1 -1 - 0 0 WGS lung CYP2A7 1549 cytochrome P450, family 2, subfamily A, polypeptide 7 19q13.2 7453 2611 608054 "NP_000755;NP_085079" "NM_000764;NM_030589" "ENSP00000301146;ENSP00000291764" candidate 0 0 3 Last Universal Common Ancestor 0 0 -1 67 chr19 41381601 41388115 WES,WGS chronic lymphocytic leukemia CYP2C18 1562 cytochrome P450, family 2, subfamily C, polypeptide 18 10q24 3085 2620 601131 "NP_000763;NP_001122397" "NM_000772;NM_001128925" "ENSP00000285979;ENSP00000341293" candidate 0 0 3 Last Universal Common Ancestor 6 0 -1 43 chr10 96443577 96495198 WGS lung CYP2C9 1559 cytochrome P450, family 2, subfamily C, polypeptide 9 10q24 3084 2623 601130 NP_000762 NM_000771 ENSP00000260682 candidate 0 0 3 Last Universal Common Ancestor 11 0 -1 95 chr10 96698440 96748782 WES melanoma CYP4A22 284541 cytochrome P450, family 4, subfamily A, polypeptide 22 1p33 16776 20575 - NP_001010969 NM_001010969 - candidate 0 0 1 Last Universal Common Ancestor 0 1 -1 17 chr1 47603158 47614466 WGS chronic lymphocytic leukemia CYP4F22 126410 cytochrome P450, family 4, subfamily F, polypeptide 22 19p13.12 8256 26820 611495 NP_775754 NM_173483 ENSP00000269703 candidate 0 0 0 Last Universal Common Ancestor 0 1 -1 -1 chr19 15636148 15662279 WES lymphoma CYP4X1 260293 cytochrome P450, family 4, subfamily X, polypeptide 1 1p33 13110 20244 - NP_828847 NM_178033 ENSP00000360968 candidate 0 0 0 Last Universal Common Ancestor 1 0 -1 -1 chr1 47489490 47515843 WES endometrium DACH2 117154 dachshund homolog 2 (Drosophila) Xq21.3 6481 16814 300608 "NP_001132986;NP_444511;NP_001132987" "NM_001139514;NM_053281;NM_001139515" "ENSP00000362223;ENSP00000420896;ENSP00000362217" candidate 0 0 0 Metazoans 2 0 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription -1 chrX 85403625 86087155 WES pancreas DAGLB 221955 diacylglycerol lipase, beta 7p22.1 17324 28923 614016 "NP_631918;NP_001136408" "NM_139179;NM_001142936" "ENSP00000391171;ENSP00000297056" candidate 0 0 0 Eukaryotes 3 1 Cellular metabolism -1 chr7 6449471 6487473 WGS lymphoma DAXX 1616 death-domain associated protein 6p21.3 4424 2681 603186 "NP_001135442;NP_001135441;NP_001241646;NP_001341" "NM_001141970;NM_001141969;NM_001254717;NR_024517;NM_001350" "ENSP00000363668;ENSP00000396876;ENSP00000266000" known 0 1 0 Metazoans 103 1 Cell cycle,Cellular metabolism,Cellular processes,DNA/RNA metabolism and transcription,Development,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction 64 chr6 33286523 33290691 CGC,WES glioblastoma,pancreas DBN1 1627 drebrin 1 5q35.3 545 2695 126660 "NP_543157;NP_004386" "NM_080881;NM_004395" "ENSP00000308532;ENSP00000292385" candidate 0 0 0 Eukaryotes 68 3 Cell cycle,Cellular processes,Development,Multicellular activities 67 chr5 176884437 176899211 WES breast DBR1 51163 debranching enzyme homolog 1 (S. cerevisiae) 3q22.3 7384 15594 607024 NP_057300 NM_016216 ENSP00000260803 candidate 0 0 0 Last Universal Common Ancestor 2 0 DNA/RNA metabolism and transcription,Regulation of transcription 27 chr3 137880734 137893637 WES gastric DCAF4L2 138009 DDB1 and CUL4 associated factor 4-like 2 8q21.3 8187 26657 - NP_689631 NM_152418 ENSP00000316496 candidate 0 0 1 Eukaryotes 0 1 -1 -1 chr8 88885015 88886199 WES breast DCHS1 8642 dachsous 1 (Drosophila) 11p15.4 4341 13681 603057 NP_003728 "NM_003737;NM_024542" ENSP00000299441 candidate 0 0 0 Last Universal Common Ancestor 1 0 Cell motility and interactions 57 chr11 6643013 6662844 WES lymphoma DCTN4 51164 dynactin 4 (p62) 5q31-q32 13126 15518 - "NP_001129116;NP_001129115;NP_057305" "NM_001135644;NM_001135643;NM_016221" "ENSP00000411251;ENSP00000416968" candidate 0 0 0 Eukaryotes 8 2 -1 70 chr5 150090714 150138555 WGS prostate DCUN1D1 54165 DCN1, defective in cullin neddylation 1, domain containing 1 (S. cerevisiae) 3q26.3 12067 18184 605905 NP_065691 NM_020640 - known 0 0 2 Eukaryotes 219 2 -1 90 chr3 182662885 182683541 CGC,Amplified DDB2 1643 damage-specific DNA binding protein 2, 48kDa 11p12-p11 2886 2718 600811 NP_000098 NM_000107 ENSP00000256996 known 0 1 0 Last Universal Common Ancestor 44 2 Cell response to stimuli,Cellular metabolism,Cellular processes,DNA/RNA metabolism and transcription 59 chr11 47236688 47260397 CGC DDIT3 1649 DNA-damage-inducible transcript 3 12q13.1-q13.2 529 2726 126337 "NP_001181982;NP_001181983;NP_001181986;NP_004074;NP_001181984;NP_001181985" "NM_001195053;NM_001195054;NM_001195057;NM_004083;NM_001195055;NM_001195056" "ENSP00000448665;ENSP00000447803;ENSP00000447188;ENSP00000340671" known 1 0 0 Vertebrates 42 2 Cell cycle,Cell response to stimuli,Cellular metabolism,DNA/RNA metabolism and transcription,Development,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction 68 chr12 57910595 57911258 CGC sarcoma DDX10 1662 DEAD (Asp-Glu-Ala-Asp) box polypeptide 10 11q22-q23 3138 2735 601235 NP_004389 NM_004398 ENSP00000314348 known 1 0 1 Last Universal Common Ancestor 5 5 -1 104 chr11 108535881 108811147 CGC leukemia DDX11 1663 DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 11 12p11 3095 2736 601150 "NP_004390;NP_085911;NP_689651" "NM_030655;NM_004399;NM_030653;NM_152438" "ENSP00000440402;ENSP00000228264;ENSP00000309965;ENSP00000384703" candidate 0 0 2 Last Universal Common Ancestor 10 0 Cell cycle,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism 82 chr12 31231328 31256964 WGS breast DDX28 55794 DEAD (Asp-Glu-Ala-Asp) box polypeptide 28 16q22.1 6357 17330 607618 NP_060850 NM_018380 ENSP00000332340 candidate 0 0 0 Last Universal Common Ancestor 23 1 -1 42 chr16 68055486 68057105 WGS lymphoma DDX3X 1654 DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, X-linked Xp11.3-p11.23 2154 2745 300160 "NP_001347;NP_001180345;NP_001180346" "NM_001356;NM_024005;NM_001193416;NM_001193417" ENSP00000382840 candidate 0 0 3 Last Universal Common Ancestor 127 12 -1 108 chrX 41193506 41206969 WES,WGS chronic lymphocytic leukemia,head and neck squamous cell carcinoma,lymphoma,medulloblastoma DDX5 1655 DEAD (Asp-Glu-Ala-Asp) box polypeptide 5 17q21 1615 2746 180630 NP_004387 NM_004396 - known 1 0 0 Last Universal Common Ancestor 162 6 Cell cycle,DNA/RNA metabolism and transcription,Regulation of transcription 109 chr17 62496044 62502237 CGC prostate DDX6 1656 DEAD (Asp-Glu-Ala-Asp) box polypeptide 6 11q23.3 2638 2747 600326 NP_004388 NM_004397 - known 1 0 2 Last Universal Common Ancestor 18 10 -1 33 chr11 118625424 118656960 CGC non-hodgkin lymphoma DEK 7913 DEK oncogene 6p22.3 503 2768 125264 "NP_001128181;NP_003463" "NM_001134709;NM_003472" ENSP00000380414 known 1 0 0 Eukaryotes 42 4 Cellular metabolism,DNA/RNA metabolism and transcription,Other,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction 95 chr6 18226405 18264218 CGC leukemia DENND4A 10260 DENN/MADD domain containing 4A 15q22.31 2662 24321 600382 "NP_005839;NP_001138295" "NM_005848;NM_001144823" "ENSP00000391167;ENSP00000396830" candidate 0 0 0 Eukaryotes 6 0 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription 13 chr15 65954192 66048788 WGS chronic lymphocytic leukemia DENND5A 23258 DENN/MADD domain containing 5A 11p15.4 11475 19344 - "NP_001230183;NP_056028" "NM_001243254;NM_015213" "ENSP00000435866;ENSP00000328524" candidate 0 0 0 Eukaryotes 2 0 -1 103 chr11 9161221 9286616 WGS liver DGUOK 1716 deoxyguanosine kinase 2p13 3273 2858 601465 "NP_550438;NP_550440" "NM_001929;NM_080916;NM_080918;NM_080917;NM_080915" "ENSP00000264093;ENSP00000306964" candidate 0 0 0 Last Universal Common Ancestor 4 0 Cellular metabolism,DNA/RNA metabolism and transcription 109 chr2 74154038 74185375 WGS prostate DHDDS 79947 dehydrodolichyl diphosphate synthase 1p36.11 12183 20603 608172 "NP_001230493;NP_079163;NP_995583;NP_001230494" "NM_001243564;NM_024887;NM_205861;NM_001243565" ENSP00000353104 candidate 0 0 0 Last Universal Common Ancestor 4 0 -1 76 chr1 26759437 26795619 WGS breast DIAPH1 1729 diaphanous homolog 1 (Drosophila) 5q31 3670 2876 602121 "NP_005210;NP_001073280" "NM_005219;NM_001079812" "ENSP00000373709;ENSP00000381565" candidate 0 0 0 Eukaryotes 30 1 Cell response to stimuli,Cellular processes 100 chr5 140896421 140998481 WES lymphoma DICER1 23405 dicer 1, ribonuclease type III 14q32.13 5875 17098 606241 "NP_001182502;NP_085124;NP_803187" "NM_001195573;NM_030621;NM_177438" "ENSP00000435681;ENSP00000376783;ENSP00000343745" known 0 1 0 Last Universal Common Ancestor 14 19 Cell cycle,DNA/RNA metabolism and transcription,Development,Regulation of intracellular processes and metabolism,Regulation of transcription 101 chr14 95556838 95599795 CGC,WGS sarcoma,sex cord-stromal tumour,testis,prostate DIDO1 11083 death inducer-obliterator 1 20q13.33 12752 2680 604140 "NP_542986;NP_071388;NP_149072;NP_542987;NP_001180299;NP_001180298" "NM_080796;NM_022105;NM_033081;NM_080797;NM_001193370;NM_001193369" "ENSP00000378752;ENSP00000378749;ENSP00000359397;ENSP00000266070;ENSP00000346692;ENSP00000378744" candidate 0 0 0 Eukaryotes 34 1 Cell cycle,Cellular metabolism,DNA/RNA metabolism and transcription 93 chr20 61510588 61542964 WGS lymphoma DIP2C 22982 DIP2 disco-interacting protein 2 homolog C (Drosophila) 10p15.3 17200 29150 611380 NP_055789 NM_014974 ENSP00000280886 candidate 0 0 0 Last Universal Common Ancestor 2 2 -1 93 chr10 323268 735518 WES breast,lung DIS3 22894 DIS3 mitotic control homolog (S. cerevisiae) 13q22.1 6338 20604 607533 "NP_055768;NP_001121698" "NM_014953;NM_001128226" ENSP00000366997 candidate 0 0 0 Last Universal Common Ancestor 31 1 DNA/RNA metabolism and transcription,Regulation of transcription 80 chr13 73333936 73355970 WES,WGS myeloma DKK2 27123 dickkopf 2 homolog (Xenopus laevis) 4q25 5658 2892 605415 NP_055236 NM_014421 ENSP00000285311 candidate 0 0 0 Eukaryotes 10 4 Regulation of intracellular processes and metabolism,Signal transduction 17 chr4 107845114 107956748 WGS chronic lymphocytic leukemia DLC1 10395 deleted in liver cancer 1 8p22 5035 2897 604258 "NP_079043;NP_006085;NP_001157743;NP_872584" "NM_024767;NM_006094;NM_001164271;NM_182643" "ENSP00000425878;ENSP00000276297" candidate 0 0 0 Last Universal Common Ancestor 10 5 Cell cycle,Cell motility and interactions,Cellular metabolism,Cellular processes,Development,Regulation of intracellular processes and metabolism,Signal transduction 83 chr8 12943323 13357580 WES pancreas DLEC1 9940 deleted in lung and esophageal cancer 1 3p21.3 7234 2899 604050 "NP_031361;NP_031363" "NM_007338;NM_007335;NM_007336;NM_007337" "ENSP00000308597;ENSP00000315914" candidate 0 0 0 Eukaryotes 5 0 Cell cycle,Regulation of intracellular processes and metabolism 47 chr3 38080717 38164093 WES,WGS pancreas,melanoma DLG3 1741 discs, large homolog 3 (Drosophila) Xq13.1 2177 2902 300189 "NP_066943;NP_065781;NP_001159750" "NM_021120;NM_020730;NM_001166278" "ENSP00000441393;ENSP00000363475;ENSP00000363480" candidate 0 0 0 Last Universal Common Ancestor 79 1 Cell cycle,Regulation of intracellular processes and metabolism 91 chrX 69665052 69722116 WES pancreas DLG4 1742 discs, large homolog 4 (Drosophila) 17p13.1 4199 2903 602887 "NP_001122299;NP_001356" "NM_001128827;NM_001365" "ENSP00000307471;ENSP00000293813" candidate 0 0 0 Last Universal Common Ancestor 124 1 Development,Multicellular activities,Signal transduction 37 chr17 7094030 7121959 WGS breast DLG5 9231 discs, large homolog 5 (Drosophila) 10q23 4972 2904 604090 NP_004738 NM_004747 ENSP00000361467 candidate 0 0 0 Eukaryotes 60 2 Cell cycle,Regulation of intracellular processes and metabolism,Signal transduction 80 chr10 79552201 79686278 WGS breast DMD 1756 dystrophin Xp21.2 2303 2928 300377 "NP_004000;NP_004010;NP_004014;NP_004004;NP_004012;NP_004009;NP_004011;NP_004003;NP_004005;NP_004008;NP_004001;NP_003997;NP_003998;NP_004002;NP_000100;NP_004006;NP_004013;NP_004007" "NM_004009;NM_004019;NM_004023;NM_004013;NM_004021;NM_004018;NM_004020;NM_004012;NM_004014;NM_004017;NM_004010;NM_004006;NM_004007;NM_004011;NM_000109;NM_004015;NM_004022;NM_004016" "ENSP00000354923;ENSP00000367948;ENSP00000367979;ENSP00000367997;ENSP00000444119;ENSP00000352894;ENSP00000340057" candidate 0 0 0 Eukaryotes 44 6 Cellular metabolism,Cellular processes,Development 78 chrX 31152217 33038315 WES,WGS gastric,chronic lymphocytic leukemia DMGDH 29958 dimethylglycine dehydrogenase 5q14.1 5789 24475 605849 NP_037523 NM_013391 ENSP00000255189 candidate 0 0 0 Last Universal Common Ancestor 0 2 Cellular metabolism -1 chr5 78293908 78365443 WGS liver DMRT2 10655 doublesex and mab-3 related transcription factor 2 9p24.3 16079 2935 604935 "NP_006548;NP_870987;NP_001124337" "NM_006557;NM_181872;NM_001130865" "ENSP00000371690;ENSP00000259622;ENSP00000305785" candidate 0 0 0 Metazoans 18 1 Cellular metabolism,DNA/RNA metabolism and transcription,Development,Regulation of intracellular processes and metabolism,Regulation of transcription -1 chr9 1051614 1057270 WGS melanoma DMRTA1 63951 DMRT-like family A1 9p21.3 10913 13826 - NP_071443 NM_022160 ENSP00000319651 candidate 0 0 0 Metazoans 12 0 Cellular metabolism,DNA/RNA metabolism and transcription,Development,Regulation of intracellular processes and metabolism,Regulation of transcription -1 chr9 22447065 22451907 WGS prostate DMXL1 1657 Dmx-like 1 5q22 9294 2937 605671 NP_005500 NM_005509 ENSP00000309690 candidate 0 0 0 Last Universal Common Ancestor 2 5 -1 47 chr5 118407265 118582911 WES liver DNAH7 56171 dynein, axonemal, heavy chain 7 2q32.3 10914 18661 610061 NP_061720 NM_018897 ENSP00000311273 candidate 0 0 0 Eukaryotes 20 0 Cell motility and interactions,Cellular processes 58 chr2 196602648 196922843 WES gastric DNAH8 1769 dynein, axonemal, heavy chain 8 6p21.2 4515 2952 603337 NP_001193856 "NM_001206927;NM_001371" ENSP00000333363 candidate 0 0 0 Eukaryotes 1 0 Cell motility and interactions,Cellular processes -1 chr6 38690586 38998165 WGS melanoma DNAH9 1770 dynein, axonemal, heavy chain 9 17p12 4511 2953 603330 "NP_001363;NP_004653" "NM_001372;NM_004662" "ENSP00000262442;ENSP00000379323" candidate 0 0 0 Eukaryotes 1 0 Cellular processes,Development,Multicellular activities 56 chr17 11501816 11872841 WES pancreas DNER 92737 delta/notch-like EGF repeat containing 2q36.3 9531 24456 607299 NP_620711 NM_139072 ENSP00000345229 candidate 0 0 0 Eukaryotes 4 0 Cell cycle,Cell motility and interactions,Cellular metabolism,Cellular processes,Development,Multicellular activities,Signal transduction -1 chr2 230223259 230579139 HTMS,WGS breast,lung,ovarian,pancreas,prostate DNM2 1785 dynamin 2 19p13.2 3852 2974 602378 "NP_001177645;NP_001005361;NP_001005360;NP_004936;NP_001005362" "NM_001190716;NM_001005361;NM_001005360;NM_004945;NM_001005362" "ENSP00000347890;ENSP00000373905;ENSP00000386192;ENSP00000352721" known 0 1 2 Last Universal Common Ancestor 108 4 Cell cycle,Cellular metabolism,Cellular processes,DNA/RNA metabolism and transcription,Development,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction 61 chr19 10828919 10941720 CGC leukemia DNMT3A 1788 DNA (cytosine-5-)-methyltransferase 3 alpha 2p23 4141 2978 602769 "NP_783329;NP_783328;NP_072046;NP_715640" "NM_175630;NM_175629;NM_022552;NM_153759" "ENSP00000324375;ENSP00000370122;ENSP00000264709;ENSP00000384852" known 0 1 0 Eukaryotes 47 11 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of transcription 20 chr2 25457151 25536853 CGC,WES leukemia,myelodysplasia DOCK2 1794 dedicator of cytokinesis 2 5q35.1 9121 2988 603122 NP_004937 NM_004946 ENSP00000256935 candidate 0 0 0 Eukaryotes 16 0 Cell motility and interactions,Cellular processes,Immune system response 21 chr5 169064331 169509859 WES pancreas DOCK4 9732 dedicator of cytokinesis 4 7q31.1 7407 19192 607679 NP_055520 NM_014705 ENSP00000410746 candidate 0 0 0 Eukaryotes 8 2 -1 70 chr7 111368333 111846193 WES,WGS chronic lymphocytic leukemia DOCK6 57572 dedicator of cytokinesis 6 19p13.2 13243 19189 614194 NP_065863 NM_020812 ENSP00000294618 candidate 0 0 0 Eukaryotes 2 1 -1 62 chr19 11310176 11373116 WGS prostate DPAGT1 1798 dolichyl-phosphate (UDP-N-acetylglucosamine) N-acetylglucosaminephosphotransferase 1 (GlcNAc-1-P transferase) 11q23.3 1879 2995 191350 NP_001373 "NM_203316;NM_001382" ENSP00000346142 candidate 0 0 0 Last Universal Common Ancestor 3 1 Cellular metabolism 95 chr11 118967711 118972365 WES breast DPEP3 64180 dipeptidase 3 16q22.1 7012 23029 609926 "NP_001123230;NP_071752" "NM_001129758;NM_022357" ENSP00000268793 candidate 0 0 0 Last Universal Common Ancestor 1 0 Cellular metabolism 9 chr16 68009671 68014358 WGS breast DPP10 57628 dipeptidyl-peptidase 10 (non-functional) 2q14.1 7083 20823 608209 "NP_001171507;NP_001171508;NP_001171505;NP_001004360;NP_065919" "NM_001178036;NM_001178037;NM_001178034;NM_001004360;NM_020868" ENSP00000386565 candidate 0 0 0 Last Universal Common Ancestor 3 0 Cellular metabolism -1 chr2 115919534 116599918 WES colorectal DPP6 1804 dipeptidyl-peptidase 6 7q36.2 525 3010 126141 "NP_001927;NP_001034439;NP_570629" "NM_001936;NM_001039350;NM_130797" "ENSP00000385578;ENSP00000367001" candidate 0 0 0 Last Universal Common Ancestor 3 0 Cellular metabolism 73 chr7 153749906 154684187 WES chronic lymphocytic leukemia,pancreas DPYD 1806 dihydropyrimidine dehydrogenase 1p22 2036 3012 612779 "NP_000101;NP_001153773" "NM_000110;NM_001160301" "ENSP00000359211;ENSP00000307107" candidate 0 0 0 Last Universal Common Ancestor 2 3 Cellular metabolism,DNA/RNA metabolism and transcription 50 chr1 97544535 98386478 WES breast,lymphoma DROSHA 29102 drosha, ribonuclease type III 5p13.3 10196 17904 608828 "NP_001093882;NP_037367" "NM_001100412;NM_013235" "ENSP00000424161;ENSP00000425979" candidate 0 0 0 Last Universal Common Ancestor 21 2 DNA/RNA metabolism and transcription,Regulation of transcription 93 chr5 31401542 31527018 WGS melanoma DSC3 1825 desmocollin 3 18q12.1 2604 3037 600271 "NP_001932;NP_077741" "NM_001941;NM_024423" "ENSP00000353608;ENSP00000392068" candidate 0 0 0 Eukaryotes 8 2 Cell motility and interactions 57 chr18 28574144 28622626 WES lymphoma DSCAML1 57453 Down syndrome cell adhesion molecule like 1 11q23 10921 14656 611782 NP_065744 NM_020693 ENSP00000315465 candidate 0 0 0 Last Universal Common Ancestor 110 3 Cell cycle,Development -1 chr11 117299047 117667974 WES colorectal DSE 29940 dermatan sulfate epimerase 6q22 5807 21144 605942 "NP_037484;NP_001074445" "NM_013352;NM_001080976" "ENSP00000404049;ENSP00000352567" candidate 0 0 1 Last Universal Common Ancestor 2 1 Cellular metabolism 63 chr6 116720414 116758505 WES liver DSG3 1830 desmoglein 3 18q12.1 1355 3050 169615 NP_001935 NM_001944 ENSP00000257189 candidate 0 0 0 Eukaryotes 4 0 Cell motility and interactions 57 chr18 29027841 29056220 WGS lung DSG4 147409 desmoglein 4 18q12.1 6387 21307 607892 "NP_001127925;NP_817123" "NM_001134453;NM_177986" ENSP00000311859 candidate 0 0 0 Eukaryotes 1 0 Cell motility and interactions,Development,Multicellular activities -1 chr18 28956875 28993555 WES glioblastoma DSPP 1834 dentin sialophosphoprotein 4q21.3 508 3054 125485 NP_055023 NM_014208 ENSP00000382213 candidate 0 0 0 Last Universal Common Ancestor 0 0 Cell response to stimuli,Development 31 chr4 88532061 88537717 WGS lymphoma DST 667 dystonin 6p12.1 222 1090 113810 "NP_056363;NP_001714" "NM_015548;NM_183380;NM_001144771;NM_001144769;NM_001144770;NM_001723;NM_020388" "ENSP00000359801;ENSP00000244364" candidate 0 0 0 Eukaryotes 60 4 Cell cycle,Cellular processes,Signal transduction 96 chr6 56323806 56507586 WGS lung DTNA 1837 dystrobrevin, alpha 18q12 3141 3057 601239 "NP_116763;NP_116760;NP_001185874;NP_001185870;NP_116757;NP_001185872;NP_001383;NP_001121647;NP_001185867;NP_001185873;NP_116761;NP_001185868;NP_001185871;NP_001185869;NP_001382;NP_001381;NP_116762" "NM_032981;NM_032978;NM_001198945;NM_001198941;NM_032975;NM_001198943;NM_001392;NM_001128175;NM_001198938;NM_001198944;NM_032979;NM_001198939;NM_001198942;NM_001198940;NM_001391;NM_001390;NM_032980" "ENSP00000451516;ENSP00000470152;ENSP00000382072;ENSP00000473078;ENSP00000405819;ENSP00000269191;ENSP00000322519;ENSP00000283365;ENSP00000336682" candidate 0 0 0 Metazoans 28 0 Multicellular activities,Signal transduction 89 chr18 32335941 32462168 WES chronic lymphocytic leukemia DTNB 1838 dystrobrevin, beta 2p24 9091 3058 602415 "NP_899204;NP_001243237;NP_001243232;NP_149160;NP_899205;NP_068707;NP_149159;NP_001243233" "NM_183360;NM_001256308;NM_001256303;NM_033148;NM_183361;NM_021907;NM_033147;NM_001256304" "ENSP00000385784;ENSP00000444463;ENSP00000384084;ENSP00000385482;ENSP00000384767;ENSP00000385193;ENSP00000384787" candidate 0 0 0 Metazoans 27 1 -1 41 chr2 25606703 25875529 WES colorectal DUSP2 1844 dual specificity phosphatase 2 2q11 4348 3068 603068 NP_004409 NM_004418 ENSP00000288943 candidate 0 0 0 Last Universal Common Ancestor 2 6 Cellular metabolism,Cellular processes,Regulation of intracellular processes and metabolism,Signal transduction 20 chr2 96809565 96811093 WES lymphoma DUSP22 56940 dual specificity phosphatase 22 6p25.3 13255 16077 - NP_064570 NM_020185 - candidate 0 0 0 Last Universal Common Ancestor 7 2 Cell cycle,Cellular metabolism,Cellular processes,Regulation of intracellular processes and metabolism,Signal transduction 99 chr6 311879 350865 WGS lung DUSP7 1849 dual specificity phosphatase 7 3p21 4125 3073 602749 NP_001938 NM_001947 ENSP00000417183 candidate 0 0 0 Last Universal Common Ancestor 10 1 Cellular metabolism,Cellular processes 8 chr3 52084834 52090382 WES lymphoma DUSP8 1850 dual specificity phosphatase 8 11p15.5 3617 3074 602038 NP_004411 NM_004420 ENSP00000380530 candidate 0 0 5 Last Universal Common Ancestor 2 4 Cellular metabolism,Cellular processes,Regulation of intracellular processes and metabolism,Signal transduction 49 chr11 1577751 1587056 WGS lymphoma DUSP9 1852 dual specificity phosphatase 9 Xq28 2136 3076 300134 NP_001386 NM_001395 ENSP00000359186 candidate 0 0 0 Last Universal Common Ancestor 7 1 Cellular metabolism,Cellular processes,Regulation of intracellular processes and metabolism,Signal transduction 53 chrX 152913408 152915757 WES lymphoma DUX4 22947 double homeobox 4 4q35 16189 3082 606009 NP_149418 NM_033178 ENSP00000451304 known 1 0 20 - 15 0 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription 0 chr4 190992204 190993658 CGC sarcoma DYNC2H1 79659 dynein, cytoplasmic 2, heavy chain 1 11q21-q22.1 - 2962 603297 "NP_001073932;NP_001368" "NM_024606;NM_001080463;NM_001377" "ENSP00000381167;ENSP00000364887" candidate 0 0 0 Eukaryotes 63 4 Cellular processes,Development 55 chr11 102980304 103349978 WGS breast DYRK2 8445 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2 12q15 4606 3093 603496 "NP_006473;NP_003574" "NM_006482;NM_003583" - known 0 0 0 Last Universal Common Ancestor 115 4 Cell cycle,Cellular metabolism,Cellular processes,Development,Regulation of intracellular processes and metabolism,Signal transduction 54 chr12 68042914 68052490 CGC,Amplified E2F3 1871 E2F transcription factor 3 6p22 2693 3115 600427 "NP_001940;NP_001230005" "NM_001949;NM_001243076" "ENSP00000443418;ENSP00000262904" known 0 0 1 Eukaryotes 36 15 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription 75 chr6 20402464 20490658 CGC,Amplified EBF1 1879 early B-cell factor 1 5q34 1256 3126 164343 NP_076870 NM_024007 ENSP00000322898 known 1 0 1 Metazoans 6 1 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription -1 chr5 158134988 158526486 CGC lipoma ECT2L 345930 epithelial cell transforming sequence 2 oncogene-like 6q24.1 - 21118 - "NP_001071174;NP_001181966" "NM_001077706;NM_001195037" ENSP00000356655 known 0 1 0 Eukaryotes 0 0 Signal transduction -1 chr6 139134412 139223761 CGC leukemia EDIL3 10085 EGF-like repeats and discoidin I-like domains 3 5q14 9350 3173 606018 NP_005702 NM_005711 - candidate 0 0 0 Eukaryotes 2 1 -1 54 chr5 83239241 83680192 WGS melanoma EDNRB 1910 endothelin receptor type B 13q22 8834 3180 131244 "NP_003982;NP_000106;NP_001116131;NP_001188326" "NM_003991;NM_000115;NM_001122659;NM_001201397" "ENSP00000335311;ENSP00000366416;ENSP00000403401" candidate 0 0 0 Metazoans 6 0 Cell cycle,Cell motility and interactions,Cell response to stimuli,Development,Multicellular activities,Regulation of intracellular processes and metabolism,Signal transduction 88 chr13 78472338 78493750 WES colorectal (non-hypermutated) EEF1A2 1917 eukaryotic translation elongation factor 1 alpha 2 20q13.3 4265 3192 602959 NP_001949 NM_001958 ENSP00000217182 known 0 0 24 Last Universal Common Ancestor 58 3 Cell cycle,Cellular metabolism,Development,Regulation of intracellular processes and metabolism,Regulation of transcription 57 chr20 62119654 62129116 CGC,Amplified EFHC2 80258 EF-hand domain (C-terminal) containing 2 Xp11.3 6540 26233 300817 NP_079460 NM_025184 ENSP00000333823 candidate 0 0 0 Eukaryotes 6 0 -1 84 chrX 44008044 44202834 WGS breast EFR3A 23167 EFR3 homolog A (S. cerevisiae) 8q24.22 17179 28970 611798 NP_055952 NM_015137 ENSP00000254624 candidate 0 0 0 Eukaryotes 1 2 -1 98 chr8 132952742 133023139 WGS chronic lymphocytic leukemia EGFLAM 133584 EGF-like, fibronectin type III and laminin G domains 5p13.2-p13.1 13433 26810 - "NP_877953;NP_001192230;NP_689616;NP_877950" "NM_182801;NM_182799;NM_001205301;NM_152403;NM_182798" "ENSP00000346964;ENSP00000313084" candidate 0 0 0 Eukaryotes 2 1 -1 -1 chr5 38258857 38464085 WES pancreas EGFR 1956 epidermal growth factor receptor 7p12 579 3236 131550 "NP_958439;NP_958441;NP_005219;NP_958440" "NM_201282;NM_201284;NM_005228;NM_201283" "ENSP00000342376;ENSP00000413843;ENSP00000345973" known 1 0 0 Last Universal Common Ancestor 483 21 Cell cycle,Cell motility and interactions,Cellular metabolism,Cellular processes,Development,Regulation of intracellular processes and metabolism,Signal transduction 94 chr7 55086971 55273307 CGC,HTMS,WES,Amplified glioma,lung,breast,glioblastoma,ovarian,pancreas,prostate EGR2 1959 early growth response 2 10q21.1 551 3239 129010 "NP_000390;NP_001129650;NP_001129651;NP_001129649" "NM_000399;NM_001136178;NM_001136179;NM_001136177" "ENSP00000242480;ENSP00000402040;ENSP00000387634" candidate 0 0 0 Last Universal Common Ancestor 18 7 Cell response to stimuli,Cellular metabolism,DNA/RNA metabolism and transcription,Development,Multicellular activities,Regulation of intracellular processes and metabolism,Regulation of transcription 26 chr10 64572970 64575789 WES chronic lymphocytic leukemia EID1 23741 EP300 interacting inhibitor of differentiation 1 15q21.1 6907 1191 605894 NP_055150 NM_014335 ENSP00000431162 candidate 0 0 0 - 43 2 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription 102 chr15 49170374 49170934 WGS liver EIF3A 8661 eukaryotic translation initiation factor 3, subunit A 10q26 3618 3271 602039 NP_003741 NM_003750 ENSP00000358140 candidate 0 0 0 Last Universal Common Ancestor 78 3 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription 106 chr10 120795554 120840188 WES gastric EIF3H 8667 eukaryotic translation initiation factor 3, subunit H 8q24.11 4885 3273 603912 NP_003747 NM_003756 - candidate 0 0 0 Eukaryotes 52 2 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription 109 chr8 117657248 117768036 HTMS breast,lung,ovarian,pancreas,prostate EIF4A2 1974 eukaryotic translation initiation factor 4A2 3q28 3062 3284 601102 NP_001958 NM_001967 ENSP00000326381 known 1 0 11 Last Universal Common Ancestor 74 2 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription 109 chr3 186502219 186507055 CGC non-hodgkin lymphoma EIF5A 1984 eukaryotic translation initiation factor 5A 17p13-p12 2555 3300 600187 "NP_001137234;NP_001137233;NP_001137232;NP_001961" "NM_001143762;NM_001143761;NM_001143760;NM_001970" "ENSP00000336702;ENSP00000390677;ENSP00000396073;ENSP00000336776" candidate 0 0 4 Last Universal Common Ancestor 25 0 Cell cycle,Cellular metabolism,Cellular processes,DNA/RNA metabolism and transcription,Development,Other,Regulation of intracellular processes and metabolism,Regulation of transcription 107 chr17 7210366 7214956 WGS lymphoma EIF5A2 56648 eukaryotic translation initiation factor 5A2 3q26.2 10426 3301 605782 NP_065123 NM_020390 ENSP00000295822 known 0 0 4 Last Universal Common Ancestor 29 4 Cellular metabolism,Cellular processes,DNA/RNA metabolism and transcription,Development,Multicellular activities,Regulation of intracellular processes and metabolism,Regulation of transcription 13 chr3 170611152 170625595 CGC,Amplified ELAVL2 1993 ELAV (embryonic lethal, abnormal vision, Drosophila)-like 2 (Hu antigen B) 9p21 3396 3313 601673 "NP_004423;NP_001164668;NP_001164666" "NM_004432;NM_001171197;NM_001171195" "ENSP00000369453;ENSP00000380479" candidate 0 0 2 Last Universal Common Ancestor 11 4 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription 19 chr9 23692558 23762232 WES lung ELF4 2000 E74-like factor 4 (ets domain transcription factor) Xq26 6499 3319 300775 "NP_001412;NP_001120669" "NM_001421;NM_001127197" "ENSP00000338608;ENSP00000311280" known 1 0 0 Metazoans 17 4 Cellular metabolism,DNA/RNA metabolism and transcription,Immune system response,Regulation of intracellular processes and metabolism,Regulation of transcription 32 chrX 129200699 129215304 CGC leukemia ELK4 2005 ELK4, ETS-domain protein (SRF accessory protein 1) 1q32 2592 3326 600246 "NP_001964;NP_068567" "NM_001973;NM_021795" ENSP00000350681 known 1 0 0 Vertebrates 9 0 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription 24 chr1 205585677 205593010 CGC prostate ELL 8178 elongation factor RNA polymerase II 19p13.1 2615 23114 600284 NP_006523 NM_006532 ENSP00000262809 known 1 0 0 Metazoans 12 0 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription 37 chr19 18555565 18632865 CGC leukemia ELMO1 9844 engulfment and cell motility 1 7p14.1 12102 16286 606420 "NP_001193409;NP_001193411;NP_055615;NP_001034548" "NR_038121;NM_001206480;NM_001206482;NM_130442;NM_014800;NR_038120;NM_001039459" - candidate 0 0 0 Eukaryotes 5 0 Cell cycle,Cellular processes,Signal transduction 59 chr7 36895159 37382294 WES liver ELN 2006 elastin 7q11.23 556 3327 130160 "NP_001075222;NP_001075224;NP_001075223;NP_001075221;NP_000492" "NM_001081753;NM_001081755;NM_001081754;NM_001081752;NM_000501" "ENSP00000252034;ENSP00000369949;ENSP00000391129;ENSP00000349540;ENSP00000369950" known 1 0 0 Mammals 24 0 DNA/RNA metabolism and transcription,Development,Multicellular activities 28 chr7 73449693 73483027 CGC,WES leukemia,pancreas ELOVL6 79071 ELOVL fatty acid elongase 6 4q25 13269 15829 611546 "NP_001124193;NP_076995" "NM_001130721;NM_024090" ENSP00000304736 candidate 0 0 0 Eukaryotes 1 1 Cellular metabolism 63 chr4 110972497 111119491 WGS chronic lymphocytic leukemia ELP4 26610 elongation protein 4 homolog (S. cerevisiae) 11p13 7377 1171 606985 NP_061913 NM_019040 ENSP00000298937 candidate 0 0 0 Eukaryotes 6 0 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription 63 chr11 31531332 31805069 HTMS breast,lung,ovarian,pancreas,prostate EML4 27436 echinoderm microtubule associated protein like 4 2p21 6310 1316 607442 "NP_061936;NP_001138548" "NM_019063;NM_001145076" ENSP00000320663 known 1 0 0 Last Universal Common Ancestor 18 5 Cell cycle,Cellular processes 63 chr2 42472644 42557344 CGC lung EN1 2019 engrailed homeobox 1 2q14.2 8835 3342 131290 NP_001417 NM_001426 ENSP00000295206 candidate 0 0 0 Eukaryotes 4 0 Cell cycle,Cellular metabolism,Cellular processes,DNA/RNA metabolism and transcription,Development,Regulation of intracellular processes and metabolism,Regulation of transcription 22 chr2 119600517 119604743 WGS lung ENO4 387712 enolase family member 4 10q25.3 - 31670 - NP_001229628 NM_001242699 ENSP00000345555 candidate 0 0 0 Last Universal Common Ancestor 0 0 -1 -1 chr10 118609078 118641177 WGS lung EP300 2033 E1A binding protein p300 22q13.2 4078 3373 602700 NP_001420 NM_001429 ENSP00000263253 known 0 1 0 Eukaryotes 406 11 Cell cycle,Cellular metabolism,Cellular processes,DNA/RNA metabolism and transcription,Development,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction 77 chr22 41489009 41574957 CGC,WES breast,colorectal,leukemia,lymphoma,pancreas,bladder EPB41L3 23136 erythrocyte membrane protein band 4.1-like 3 18p11.32 5622 3380 605331 NP_036439 NM_012307 ENSP00000343158 candidate 0 0 0 Metazoans 18 1 Cellular processes 72 chr18 5394685 5489182 WES gastric EPC1 80314 enhancer of polycomb homolog 1 (Drosophila) 10p11 9941 19876 610999 NP_079485 NM_025209 ENSP00000263062 candidate 0 0 0 Eukaryotes 19 7 Cell cycle,Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription -1 chr10 32557994 32635843 WES pancreas EPG5 57724 ectopic P-granules autophagy protein 5 homolog (C. elegans) 18q12.3 11157 29331 - NP_066015 NM_020964 ENSP00000282041 candidate 0 0 0 Eukaryotes 21 0 -1 -1 chr18 43432435 43547205 WES breast,chronic lymphocytic leukemia EPHA1 2041 EPH receptor A1 7q34 1554 3385 179610 NP_005223 NM_005232 ENSP00000275815 candidate 0 0 0 Last Universal Common Ancestor 1 1 Cellular metabolism,Cellular processes,Signal transduction 36 chr7 143088553 143105898 HTMS sarcoma EPHA3 2042 EPH receptor A3 3p11.2 1555 3387 179611 "NP_872585;NP_005224" "NM_182644;NM_005233" "ENSP00000337451;ENSP00000399926" candidate 0 0 0 Last Universal Common Ancestor 7 0 Cellular metabolism,Cellular processes,Signal transduction 27 chr3 89156899 89528649 HTMS,WES lung,colorectal EPHA4 2043 EPH receptor A4 2q36.1 3719 3388 602188 NP_004429 NM_004438 ENSP00000281821 candidate 0 0 0 Last Universal Common Ancestor 7 6 Cellular metabolism,Cellular processes,Signal transduction 21 chr2 222290751 222436968 WGS chronic lymphocytic leukemia EPHA5 2044 EPH receptor A5 4q13.1 2474 3389 600004 "NP_004430;NP_872272" "NM_004439;NM_182472" ENSP00000273854 candidate 0 0 0 Last Universal Common Ancestor 0 2 Cellular metabolism,Cellular processes,Signal transduction 46 chr4 66189835 66535460 HTMS breast,lung,ovarian,pancreas,prostate,sarcoma EPHA7 2045 EPH receptor A7 6q16.1 3721 3390 602190 NP_004431 NM_004440 ENSP00000358309 candidate 0 0 0 Last Universal Common Ancestor 13 3 Cellular metabolism,Cellular processes,Signal transduction 10 chr6 93953147 94129059 HTMS,WES sarcoma,head and neck squamous cell carcinoma,prostate EPHB1 2047 EPH receptor B1 3q21-q23 2790 3392 600600 NP_004432 NM_004441 ENSP00000381097 candidate 0 0 0 Last Universal Common Ancestor 5 0 Cellular metabolism,Cellular processes,Development,Signal transduction 49 chr3 134514474 134977959 HTMS,WES breast,lung,ovarian,pancreas,prostate,chronic lymphocytic leukemia EPHB4 2050 EPH receptor B4 7q22 2481 3395 600011 NP_004435 NM_004444 ENSP00000350896 candidate 0 0 0 Last Universal Common Ancestor 2 1 Cellular metabolism,Cellular processes,Development,Signal transduction 77 chr7 100401086 100424652 WGS melanoma EPHB6 2051 EPH receptor B6 7q33-q35 4133 3396 602757 NP_004436 NM_004445 ENSP00000376684 candidate 0 0 0 Last Universal Common Ancestor 5 0 Cellular metabolism,Cellular processes,Signal transduction 71 chr7 142560986 142568654 WES colorectal EPS15 2060 epidermal growth factor receptor pathway substrate 15 1p32 8968 3419 600051 "NP_001153441;NP_001972" "NM_001159969;NM_001981" ENSP00000360798 known 1 0 0 Eukaryotes 133 0 Cellular processes,Signal transduction 94 chr1 51822375 51946995 CGC leukemia ERBB2 2064 v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian) 17q11.2-q12|17q21.1 1281 3430 164870 "NP_001005862;NP_004439" "NM_001005862;NM_004448" "ENSP00000385185;ENSP00000269571" known 1 0 0 Last Universal Common Ancestor 106 15 Cell cycle,Cell motility and interactions,Cellular metabolism,Cellular processes,Development,Immune system response,Multicellular activities,Regulation of intracellular processes and metabolism,Signal transduction 71 chr17 37856492 37884294 CGC,HTMS,WES,WGS,Amplified breast,gastric,lung,other,ovarian,glioblastoma ERBB2IP 55914 erbb2 interacting protein 5q12.3 6090 15842 606944 "NP_001240630;NP_001240628;NP_001240627;NP_001006600;NP_001240626;NP_061165" "NM_001253701;NM_001253699;NM_001253698;NM_001006600;NM_001253697;NM_018695" "ENSP00000370322;ENSP00000284037;ENSP00000370330" candidate 0 0 0 Last Universal Common Ancestor 38 9 Cell cycle,Cellular processes,Development,Signal transduction 83 chr5 65288547 65374355 WES lymphoma ERBB3 2065 v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) 12q13 1820 3431 190151 "NP_001973;NP_001005915" "NM_001982;NM_001005915" "ENSP00000415753;ENSP00000267101" candidate 0 0 0 Last Universal Common Ancestor 53 6 Cell cycle,Cell motility and interactions,Cellular metabolism,Cellular processes,Development,Multicellular activities,Regulation of intracellular processes and metabolism,Signal transduction 89 chr12 56474085 56495836 HTMS,WES breast,lung,ovarian,pancreas,prostate,bladder ERBB4 2066 v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian) 2q33.3-q34 2767 3432 600543 "NP_001036064;NP_005226" "NM_001042599;NM_005235" "ENSP00000403204;ENSP00000342235" candidate 0 0 0 Last Universal Common Ancestor 71 4 Cellular metabolism,Cellular processes,Signal transduction 83 chr2 212248343 213403254 HTMS breast,lung,ovarian,pancreas,prostate,sarcoma ERC1 23085 ELKS/RAB6-interacting/CAST family member 1 12p13.3 6181 17072 607127 "NP_829884;NP_829883" "NR_027946;NR_027948;NM_178040;NR_027949;NM_178039" ENSP00000468263 known 1 0 0 Last Universal Common Ancestor 8 5 Cell cycle,Cellular metabolism,Cellular processes,DNA/RNA metabolism and transcription,Development,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction 93 chr12 1137070 1599393 CGC thyroid ERC2 26059 ELKS/RAB6-interacting/CAST family member 2 3p14.3 10810 31922 - NP_056391 NM_015576 ENSP00000288221 candidate 0 0 0 Last Universal Common Ancestor 6 0 -1 27 chr3 55733406 56469035 WGS liver ERCC2 2068 excision repair cross-complementing rodent repair deficiency, complementation group 2 19q13.3 530 3434 126340 "NP_001124339;NP_000391" "NM_001130867;NM_000400" "ENSP00000375808;ENSP00000431229" known 0 1 0 Last Universal Common Ancestor 24 0 Cell cycle,Cell response to stimuli,Cellular metabolism,DNA/RNA metabolism and transcription,Development,Regulation of intracellular processes and metabolism,Regulation of transcription 4 chr19 45854890 45873489 CGC ERCC3 2071 excision repair cross-complementing rodent repair deficiency, complementation group 3 (xeroderma pigmentosum group B complementing) 2q21 593 3435 133510 NP_000113 NM_000122 ENSP00000285398 known 0 1 0 Last Universal Common Ancestor 38 2 Cell cycle,Cell response to stimuli,Cellular metabolism,DNA/RNA metabolism and transcription,Development,Regulation of intracellular processes and metabolism,Regulation of transcription 38 chr2 128015175 128051295 CGC ERCC4 2072 excision repair cross-complementing rodent repair deficiency, complementation group 4 16p13.12 594 3436 133520 NP_005227 NM_005236 ENSP00000310520 known 0 1 0 Last Universal Common Ancestor 25 1 Cell response to stimuli,Cellular metabolism,Cellular processes,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription 48 chr16 14014023 14042201 CGC ERCC5 2073 excision repair cross-complementing rodent repair deficiency, complementation group 5 13q33 595 3437 133530 NP_000114 NM_000123 ENSP00000347978 known 0 1 0 Last Universal Common Ancestor 23 3 Cell cycle,Cell response to stimuli,Cellular metabolism,DNA/RNA metabolism and transcription,Development,Regulation of intracellular processes and metabolism 58 chr13 103498617 103528250 CGC,WGS melanoma ERCC6 2074 excision repair cross-complementing rodent repair deficiency, complementation group 6 10q11.23 596 3438 609413 NP_000115 NM_000124 ENSP00000348089 candidate 0 0 0 Last Universal Common Ancestor 44 0 Cell response to stimuli,Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription 93 chr10 50666864 50741010 WES colorectal,gastric ERG 2078 v-ets erythroblastosis virus E26 oncogene homolog (avian) 21q22.3 1298 3446 165080 "NP_891548;NP_001129626;NP_004440;NP_001230357;NP_001230358;NP_001129627;NP_001230361" "NM_182918;NM_001136154;NM_001243433;NM_004449;NM_001243428;NM_001243429;NM_001136155;NM_001243432" "ENSP00000414150;ENSP00000381871;ENSP00000394694;ENSP00000288319" known 1 0 0 Metazoans 44 2 Cellular metabolism,Cellular processes,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction 61 chr21 39755328 39947624 CGC leukemia,prostate,sarcoma ERRFI1 54206 ERBB receptor feedback inhibitor 1 1p36 9218 18185 608069 NP_061821 NM_018948 ENSP00000366702 candidate 0 0 0 Eukaryotes 11 1 -1 -1 chr1 8073273 8075679 WGS liver ESPL1 9700 extra spindle pole bodies homolog 1 (S. cerevisiae) 12q 6825 16856 604143 NP_036423 NM_012291 ENSP00000257934 candidate 0 0 0 Eukaryotes 9 4 Cell cycle,Cellular metabolism,Cellular processes,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism 56 chr12 53662551 53687255 WES bladder ETS1 2113 v-ets erythroblastosis virus E26 oncogene homolog 1 (avian) 11q23.3 1260 3488 164720 "NP_001137292;NP_001155894;NP_005229" "NM_001143820;NM_001162422;NM_005238" "ENSP00000376436;ENSP00000441430" candidate 0 0 0 Metazoans 104 9 Cell cycle,Cellular metabolism,DNA/RNA metabolism and transcription,Development,Multicellular activities,Regulation of intracellular processes and metabolism,Regulation of transcription 31 chr11 128332259 128443025 HTMS,WES breast,lung,ovarian,pancreas,prostate,non-hodgkin lymphoma ETV1 2115 ets variant 1 7p21.3 2765 3490 600541 "NP_001156624;NP_001156623;NP_001156621;NP_001156620;NP_001156622;NP_004947;NP_001156619" "NM_001163152;NM_001163151;NM_001163149;NM_001163148;NM_001163150;NM_004956;NM_001163147" "ENSP00000242066;ENSP00000340853;ENSP00000411626;ENSP00000382293;ENSP00000405327" known 1 0 0 Metazoans 22 1 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription 89 chr7 13935494 14028677 CGC,Amplified prostate,sarcoma ETV4 2118 ets variant 4 17q21 2833 3493 600711 "NP_001073143;NP_001977" "NM_001079675;NM_001986" "ENSP00000321835;ENSP00000443846;ENSP00000377273" known 1 0 0 Metazoans 15 1 Cell cycle,Cell motility and interactions,Cellular metabolism,DNA/RNA metabolism and transcription,Development,Regulation of intracellular processes and metabolism,Regulation of transcription 11 chr17 41605890 41622985 CGC prostate,sarcoma ETV5 2119 ets variant 5 3q28 9035 3494 601600 NP_004445 NM_004454 ENSP00000306894 known 1 0 0 Metazoans 16 1 Cellular metabolism,DNA/RNA metabolism and transcription,Development,Regulation of intracellular processes and metabolism,Regulation of transcription 79 chr3 185766431 185823657 CGC,WGS prostate,melanoma ETV6 2120 ets variant 6 12p13 15976 3495 600618 NP_001978 NM_001987 - known 1 0 0 Metazoans 26 1 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription 13 chr12 11905384 12043977 CGC,WES breast,leukemia,lymphoma,myelodysplasia,sarcoma EVPL 2125 envoplakin 17q25 3352 3503 601590 NP_001979 NM_001988 ENSP00000301607 candidate 0 0 0 Eukaryotes 19 0 Cellular metabolism,Cellular processes,Development 4 chr17 74003187 74023279 WES pancreas EWSR1 2130 Ewing sarcoma breakpoint region 1 22q12.2 592 3508 133450 "NP_053733;NP_001156759;NP_005234;NP_001156758;NP_001156757" "NM_013986;NM_001163287;NM_005243;NM_001163286;NM_001163285" "ENSP00000385726;ENSP00000327456;ENSP00000381031;ENSP00000400142" known 1 0 1 Eukaryotes 333 0 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription 109 chr22 29668370 29696148 CGC desmoplastic small round cell tumor,leukemia,myoepithelioma,sarcoma EXOC1 55763 exocyst complex component 1 4q12 7615 30380 607879 "NP_060731;NP_839955;NP_001020095" "NM_018261;NM_178237;NM_001024924" "ENSP00000370695;ENSP00000326514;ENSP00000334431" candidate 0 0 0 Eukaryotes 40 0 Cellular processes 102 chr4 56724490 56770658 WGS melanoma EXOC2 55770 exocyst complex component 2 6p25.3 11544 24968 - NP_060773 NM_018303 ENSP00000230449 candidate 0 0 0 Eukaryotes 18 3 Cellular processes 23 chr6 486674 637818 HTMS breast,lung,ovarian,pancreas,prostate EXOC4 60412 exocyst complex component 4 7q31 12185 30389 608185 "NP_001032203;NP_068579" "NM_001037126;NM_021807" "ENSP00000376868;ENSP00000253861" candidate 0 0 0 Eukaryotes 31 1 Cellular processes -1 chr7 132937858 133749278 WES colorectal EXOC8 149371 exocyst complex component 8 1q42.2 9943 24659 - NP_787072 NM_175876 ENSP00000353564 candidate 0 0 0 Eukaryotes 36 1 Cellular processes -1 chr1 231471317 231473491 WES pancreas EXPH5 23086 exophilin 5 11q22.3 8341 30578 612878 NP_055880 "NM_001144763;NM_001144765;NM_015065" ENSP00000265843 candidate 0 0 0 Mammals 3 0 Cellular processes 87 chr11 108380267 108464263 WES pancreas EXT1 2131 exostosin 1 8q24.11 598 3512 608177 NP_000118 NM_000127 - known 0 1 0 Eukaryotes 6 1 Cell cycle,Cellular metabolism,Development,Regulation of intracellular processes and metabolism,Signal transduction 87 chr8 118811954 119123285 CGC EXT2 2132 exostosin 2 11p12-p11 599 3513 608210 "NP_997005;NP_001171554;NP_000392" "NM_207122;NM_001178083;NM_000401" "ENSP00000379032;ENSP00000351509;ENSP00000431173" known 0 1 0 Eukaryotes 34 1 Cell cycle,Cellular metabolism,Development,Regulation of intracellular processes and metabolism,Signal transduction 91 chr11 44117803 44265834 CGC,HTMS breast,lung,ovarian,pancreas,prostate EYA4 2070 eyes absent homolog 4 (Drosophila) 6q23 4648 3522 603550 "NP_004091;NP_742101;NP_742103" "NM_004100;NM_172103;NM_172105;NM_172104" "ENSP00000356870;ENSP00000347294" candidate 0 0 0 Eukaryotes 1 12 Cell response to stimuli,Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription 20 chr6 133595919 133849940 WES colorectal EYS 346007 eyes shut homolog (Drosophila) 6q12 16853 21555 612424 "NP_938024;NP_001136273;NP_001136272" "NM_198283;NM_001142801;NM_001142800" "ENSP00000424243;ENSP00000377042;ENSP00000341818" candidate 0 0 0 Last Universal Common Ancestor 0 3 -1 -1 chr6 64430495 66205303 HTMS breast,lung,ovarian,pancreas,prostate EZH2 2146 enhancer of zeste homolog 2 (Drosophila) 7q35-q36 3342 3527 601573 "NP_001190178;NP_001190177;NP_694543;NP_004447;NP_001190176" "NM_001203249;NM_001203248;NM_152998;NM_004456;NM_001203247" "ENSP00000419711;ENSP00000419856;ENSP00000419050;ENSP00000320147;ENSP00000223193" known 0 1 0 Last Universal Common Ancestor 128 15 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription 19 chr7 148504741 148544390 CGC,WES lymphoma,leukemia,myelodysplasia,non-hodgkin lymphoma EZR 7430 ezrin 6q25.3 475 12691 123900 "NP_003370;NP_001104547" "NM_003379;NM_001111077" "ENSP00000356042;ENSP00000338934" known 1 0 0 Eukaryotes 109 3 Cell motility and interactions,Cellular processes,Development,Regulation of intracellular processes and metabolism 105 chr6 159187949 159210403 CGC lung F13A1 2162 coagulation factor XIII, A1 polypeptide 6p25.3-p24.3 604 3531 134570 NP_000120 NM_000129 ENSP00000264870 candidate 0 0 0 Metazoans 24 0 Cellular metabolism,Cellular processes,Multicellular activities 95 chr6 6145855 6318897 WGS chronic lymphocytic leukemia F2RL2 2151 coagulation factor II (thrombin) receptor-like 2 5q13 3561 3539 601919 NP_004092 NM_004101 ENSP00000296641 candidate 0 0 0 Vertebrates 16 0 Multicellular activities,Signal transduction 17 chr5 75913410 75919055 WGS melanoma F8 2157 coagulation factor VIII, procoagulant component Xq28 2384 3546 300841 "NP_000123;NP_063916" "NM_000132;NM_019863" "ENSP00000353393;ENSP00000327895" candidate 0 0 0 Eukaryotes 27 0 Cell response to stimuli,Immune system response,Multicellular activities 89 chrX 154065875 154250827 WES colorectal,pancreas FAAH2 158584 fatty acid amide hydrolase 2 Xp11.21 6551 26440 300654 NP_777572 NM_174912 ENSP00000364035 candidate 0 0 0 Last Universal Common Ancestor 1 1 -1 -1 chrX 57313259 57515362 WES head and neck squamous cell carcinoma FADD 8772 Fas (TNFRSF6)-associated via death domain 11q13.3 3909 3573 602457 NP_003815 NM_003824 ENSP00000301838 known 0 0 0 Metazoans 66 6 Cell cycle,Development,Regulation of intracellular processes and metabolism,Signal transduction 32 chr11 70049566 70052576 CGC,Amplified FAM107B 83641 family with sequence similarity 107, member B 10p13 12575 23726 - NP_113641 NM_031453 ENSP00000181796 candidate 0 0 0 Metazoans 3 1 -1 -1 chr10 14563192 14816662 WGS breast FAM111B 374393 family with sequence similarity 111, member B 11q12.1 7096 24200 - "NP_945185;NP_001136176;NP_001136175" "NM_198947;NM_001142704;NM_001142703" "ENSP00000393855;ENSP00000341565" candidate 0 0 0 Eukaryotes 3 1 -1 -1 chr11 58877099 58893772 WES kidney FAM117A 81558 family with sequence similarity 117, member A 17q21.33 17432 24179 - NP_110429 NM_030802 ENSP00000240364 candidate 0 0 0 Metazoans 0 0 -1 105 chr17 47788620 47841449 WES chronic lymphocytic leukemia FAM123B 139285 family with sequence similarity 123B Xq11.2 6565 26837 300647 NP_689637 NM_152424 ENSP00000329117 known 0 1 0 Vertebrates 7 1 -1 -1 chrX 63409762 63413166 CGC,WES Wilms,colorectal (non-hypermutated) FAM132A 388581 family with sequence similarity 132, member A 1p36.33 - 32308 - NP_001014980 NM_001014980 ENSP00000329137 candidate 0 0 0 Metazoans 0 0 -1 -1 chr1 1177931 1182070 WGS glioblastoma FAM133A 286499 family with sequence similarity 133, member A Xq21.32 6562 26748 - "NP_001164582;NP_001164580;NP_001164581;NP_775969" "NM_001171111;NM_001171109;NM_001171110;NM_173698" "ENSP00000348067;ENSP00000441389;ENSP00000318974;ENSP00000362169" candidate 0 0 3 Eukaryotes 0 3 -1 -1 chrX 92964419 92965162 WES lung FAM135B 51059 family with sequence similarity 135, member B 8q24.23 14230 28029 - NP_056996 NM_015912 ENSP00000378710 candidate 0 0 0 Eukaryotes 2 0 -1 -1 chr8 139144839 139380226 WES head and neck squamous cell carcinoma FAM13A 10144 family with sequence similarity 13, member A 4q22.1 10944 19367 613299 "NP_001015045;NP_055698" "NM_001015045;NM_014883" "ENSP00000378450;ENSP00000264344" candidate 0 0 0 Eukaryotes 0 0 Signal transduction 95 chr4 89649687 89950800 WGS liver FAM13C 220965 family with sequence similarity 13, member C 10q21.1 16875 19371 - "NP_001001971;NP_001160170;NP_937858;NP_001137245" "NM_001001971;NM_001166698;NM_198215;NM_001143773" "ENSP00000391993;ENSP00000362974;ENSP00000362975" candidate 0 0 0 Metazoans 2 0 -1 4 chr10 61007377 61122220 WGS glioblastoma FAM160B1 57700 family with sequence similarity 160, member B1 10q25.3 17219 29320 - "NP_001128523;NP_065991" "NM_001135051;NM_020940" "ENSP00000358253;ENSP00000358251" candidate 0 0 0 Eukaryotes 3 1 -1 -1 chr10 116581838 116621296 WGS lung FAM161A 84140 family with sequence similarity 161, member A 2p15 - 25808 613596 "NP_001188472;NP_115556" "NM_001201543;NR_037710;NM_032180" "ENSP00000385158;ENSP00000385893" candidate 0 0 0 Eukaryotes 2 0 -1 -1 chr2 62053593 62081176 WES colorectal FAM171A1 221061 family with sequence similarity 171, member A1 10p13 18581 23522 - NP_001010924 NM_001010924 ENSP00000367356 candidate 0 0 0 Vertebrates 11 6 -1 97 chr10 15254917 15413051 WGS chronic lymphocytic leukemia FAM171B 165215 family with sequence similarity 171, member B 2q32.1 13907 29412 - NP_803237 NM_177454 - candidate 0 0 0 Vertebrates 2 5 -1 -1 chr2 187558901 187627547 WES breast FAM193A 8603 family with sequence similarity 193, member A 4p16.3 9850 16822 - NP_003695 NM_003704 "ENSP00000324587;ENSP00000427505;ENSP00000421200;ENSP00000372290" candidate 0 0 0 Metazoans 0 1 -1 96 chr4 2632732 2733592 WGS prostate FAM193B 54540 family with sequence similarity 193, member B 5q35.3 7671 25524 - NP_001177875 "NM_019057;NM_001190946;NR_024019" ENSP00000422131 candidate 0 0 0 Metazoans 13 0 -1 91 chr5 176948979 176981459 WES colorectal FAM19A5 25817 family with sequence similarity 19 (chemokine (C-C motif)-like), member A5 22q13.32 13295 21592 - "NP_056196;NP_001076436" "NM_015381;NM_001082967" ENSP00000351043 candidate 0 0 0 Vertebrates 0 0 -1 -1 chr22 48885405 49103659 WGS glioblastoma FAM22A 728118 family with sequence similarity 22, member A 10q23.2 - 23438 - NP_001092808 NM_001099338 ENSP00000371126 known 1 0 5 Mammals 3 1 -1 -1 chr10 88985588 88994462 CGC sarcoma FAM22B 729262 family with sequence similarity 22, member B 10q22.3 - 23445 - - - - known 1 0 -1 Mammals 1 1 -1 -1 - 0 0 CGC sarcoma FAM22D 728130 family with sequence similarity 22, member D 10q23.2 - 23447 - NP_001009610 NM_001009610 - candidate 0 0 6 Mammals 0 1 -1 -1 chr10 89118023 89125562 WGS glioblastoma FAM46C 54855 family with sequence similarity 46, member C 1p12 13312 24712 613952 NP_060179 NM_017709 ENSP00000358458 known 0 1 1 Eukaryotes 9 2 -1 40 chr1 118165491 118166663 CGC,WES,WGS myeloma FAM86C1 55199 family with sequence similarity 86, member C1 11q13.4 13337 25561 - "NP_001093123;NP_060642;NP_689776" "NM_001099653;NM_018172;NM_152563" "ENSP00000352182;ENSP00000325662" candidate 0 0 12 Eukaryotes 3 0 -1 13 chr11 71498583 71510690 WGS lymphoma FAM92B 339145 family with sequence similarity 92, member B 16q24.1 13488 24781 - NP_940893 NM_198491 ENSP00000443411 candidate 0 0 0 Vertebrates 0 0 -1 -1 chr16 85132794 85144068 WES pancreas FANCA 2175 Fanconi anemia, complementation group A 16q24.3 6186 3582 607139 "NP_001018122;NP_000126" "NM_001018112;NM_000135" "ENSP00000373952;ENSP00000373953" known 0 1 0 Metazoans 16 1 DNA/RNA metabolism and transcription 42 chr16 89805012 89883023 CGC FANCC 2176 Fanconi anemia, complementation group C 9q22.3 1967 3584 613899 "NP_001230673;NP_000127;NP_001230672" "NM_001243744;NM_000136;NM_001243743" "ENSP00000289081;ENSP00000364454" known 0 1 0 Metazoans 39 1 DNA/RNA metabolism and transcription 98 chr9 97863992 98011573 CGC FANCD2 2177 Fanconi anemia, complementation group D2 3p26 1968 3585 613984 "NP_001018125;NP_149075" "NM_001018115;NM_033084" "ENSP00000373318;ENSP00000287647" known 0 1 0 Eukaryotes 52 1 Cell response to stimuli,DNA/RNA metabolism and transcription -1 chr3 10070342 10140631 CGC FANCE 2178 Fanconi anemia, complementation group E 6p22-p21 2943 3586 613976 NP_068741 NM_021922 ENSP00000229769 known 0 1 0 Eukaryotes 17 1 DNA/RNA metabolism and transcription 48 chr6 35420323 35434119 CGC FANCF 2188 Fanconi anemia, complementation group F 11p15 4589 3587 613897 NP_073562 NM_022725 ENSP00000330875 known 0 1 0 Metazoans 21 0 DNA/RNA metabolism and transcription 2 chr11 22646235 22647356 CGC FANCG 2189 Fanconi anemia, complementation group G 9p13 4262 3588 602956 NP_004620 NM_004629 ENSP00000367910 known 0 1 0 Last Universal Common Ancestor 46 2 Cell cycle,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Signal transduction 21 chr9 35074108 35079521 CGC FANCM 57697 Fanconi anemia, complementation group M 14q21.2 13876 23168 609644 NP_065988 NM_020937 ENSP00000267430 candidate 0 0 0 Last Universal Common Ancestor 42 2 DNA/RNA metabolism and transcription -1 chr14 45605235 45669208 WGS glioblastoma FAS 355 Fas (TNF receptor superfamily, member 6) 10q24.1 609 11920 134637 "NP_690610;NP_690611;NP_000034" "NM_152871;NR_028036;NM_152874;NR_028033;NM_152872;NM_152875;NM_152877;NR_028035;NR_028034;NM_152873;NM_000043;NM_152876" ENSP00000347979 known 0 1 0 Last Universal Common Ancestor 94 4 Cell cycle,Development,Regulation of intracellular processes and metabolism,Signal transduction 81 chr10 90762786 90774204 CGC,WES lymphoma,skin,testis,non-hodgkin lymphoma FAT1 2195 FAT tumor suppressor homolog 1 (Drosophila) 4q35 2986 3595 600976 NP_005236 NM_005245 ENSP00000406229 candidate 0 0 0 Last Universal Common Ancestor 5 0 Cell motility and interactions,Cellular processes,Development 91 chr4 187509749 187630981 WES head and neck squamous cell carcinoma FAT2 2196 FAT tumor suppressor homolog 2 (Drosophila) 5q33.1 5041 3596 604269 NP_001438 NM_001447 ENSP00000261800 candidate 0 0 0 Last Universal Common Ancestor 0 0 Cell motility and interactions 13 chr5 150885129 150948492 WES,WGS non-hodgkin lymphoma,pancreas,melanoma FAT3 120114 FAT tumor suppressor homolog 3 (Drosophila) 11q14.3 - 23112 612483 NP_001008781 NM_001008781 ENSP00000387040 candidate 0 0 0 Last Universal Common Ancestor 3 6 Cell motility and interactions -1 chr11 92085279 92624276 WES,WGS chronic lymphocytic leukemia,liver FAT4 79633 FAT tumor suppressor homolog 4 (Drosophila) 4q28.1 7637 23109 612411 NP_078858 NM_024582 ENSP00000377862 candidate 0 0 0 Last Universal Common Ancestor 8 1 Cell motility and interactions 47 chr4 126237567 126412920 WES gastric FBN2 2201 fibrillin 2 5q23-q31 416 3604 612570 NP_001990 NM_001999 ENSP00000262464 candidate 0 0 0 Last Universal Common Ancestor 9 5 Development 49 chr5 127595150 127873296 WES colorectal FBXO11 80204 F-box protein 11 2p16.3 6985 13590 607871 "NP_079409;NP_001177203" "NM_018693;NM_025133;NM_001190274;NM_012167" "ENSP00000384823;ENSP00000385398" known 0 1 0 Last Universal Common Ancestor 26 6 Cellular metabolism,Cellular processes 66 chr2 48035260 48132859 CGC,WES,WGS lymphoma FBXO31 79791 F-box protein 31 16q24.2 10954 16510 609102 NP_079011 "NM_024735;NR_024568" - candidate 0 0 0 Eukaryotes 7 2 -1 12 chr16 87364897 87417350 WES lymphoma FBXO32 114907 F-box protein 32 8q24.13 5966 16731 606604 "NP_001229392;NP_680482;NP_478136" "NM_001242463;NM_148177;NM_058229" ENSP00000428205 candidate 0 0 0 Metazoans 17 0 -1 -1 chr8 124515616 124553254 HTMS breast,lung,ovarian,pancreas,prostate FBXW7 55294 F-box and WD repeat domain containing 7 4q31.3 5888 16712 606278 "NP_001013433;NP_060785;NP_361014" "NM_001013415;NM_018315;NM_033632" "ENSP00000296555;ENSP00000263981;ENSP00000281708" known 0 1 0 Last Universal Common Ancestor 57 12 Cellular metabolism,Cellular processes 47 chr4 153244036 153332955 CGC,HTMS,WES colorectal,endometrium,leukemia,breast,lung,ovarian,pancreas,prostate,sarcoma,colorectal (non-hypermutated),head and neck squamous cell carcinoma FCER1A 2205 "Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide" 1q23 917 3609 147140 NP_001992 NM_002001 ENSP00000357097 candidate 0 0 0 Eukaryotes 4 0 Cell response to stimuli,Cellular metabolism,Cellular processes,Immune system response,Regulation of intracellular processes and metabolism,Signal transduction 33 chr1 159272155 159277719 HTMS,WES breast,lung,ovarian,pancreas,prostate,melanoma FCGR2B 2213 Fc fragment of IgG, low affinity IIb, receptor (CD32) 1q23 6849 3618 604590 "NP_001177757;NP_001002273;NP_001002275;NP_003992;NP_001002274" "NM_001190828;NM_001002273;NM_001002275;NM_004001;NM_001002274" ENSP00000351497 known 1 0 2 Mammals 24 0 Signal transduction 39 chr1 161633032 161647340 CGC leukemia FCRL4 83417 Fc receptor-like 4 1q21 16168 18507 605876 NP_112572 NM_031282 ENSP00000271532 known 1 0 0 Eukaryotes 2 1 -1 -1 chr1 157545317 157559252 CGC non-hodgkin lymphoma FCRL5 83416 Fc receptor-like 5 1q21 16169 18508 605877 "NP_112571;NP_001182317" "NM_031281;NM_001195388" ENSP00000354691 candidate 0 0 0 Eukaryotes 0 0 -1 -1 chr1 157485395 157516988 WES breast FETUB 26998 fetuin B 3q27 9335 3658 605954 NP_055190 NM_014375 ENSP00000265029 candidate 0 0 0 Eukaryotes 7 1 -1 62 chr3 186358250 186370417 WGS lung FEV 54738 FEV (ETS oncogene family) 2q36 6193 18562 607150 NP_059991 NM_017521 ENSP00000295727 known 1 0 0 Metazoans 0 0 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription 5 chr2 219846392 219849797 CGC sarcoma FGA 2243 fibrinogen alpha chain 4q28 619 3661 134820 "NP_000499;NP_068657" "NM_000508;NM_021871" "ENSP00000306361;ENSP00000385981" candidate 0 0 0 Eukaryotes 11 6 Cellular metabolism,Cellular processes,Development,Multicellular activities,Signal transduction 61 chr4 155505279 155511839 WGS breast FGD1 2245 FYVE, RhoGEF and PH domain containing 1 Xp11.21 2373 3663 300546 NP_004454 NM_004463 ENSP00000364277 candidate 0 0 0 Eukaryotes 7 0 Cellular processes,Development,Regulation of intracellular processes and metabolism,Signal transduction 77 chrX 54472545 54521865 WGS melanoma FGD5 152273 FYVE, RhoGEF and PH domain containing 5 3p25.1 13322 19117 - NP_689749 NM_152536 ENSP00000285046 candidate 0 0 0 Eukaryotes 0 0 Cellular processes,Development,Regulation of intracellular processes and metabolism,Signal transduction -1 chr3 14860579 14974239 WGS prostate FGFR1 2260 fibroblast growth factor receptor 1 8p12 634 3688 136350 "NP_075594;NP_056934;NP_001167534;NP_001167535;NP_075598;NP_001167536;NP_075593;NP_001167537;NP_001167538" "NM_023106;NM_015850;NM_001174063;NM_001174064;NM_023110;NM_001174065;NM_023111;NM_023105;NM_001174066;NM_023107;NM_001174067;NM_023108;NM_032191;NM_023109" "ENSP00000432972;ENSP00000393312;ENSP00000380280;ENSP00000400162" known 1 0 0 Last Universal Common Ancestor 60 7 Cell cycle,Cellular metabolism,Cellular processes,Development,Signal transduction 97 chr8 38271149 38315054 CGC,Amplified myeloma,non-hodgkin lymphoma FGFR1OP 11116 FGFR1 oncogene partner 6q27 10392 17012 605392 "NP_919410;NP_008976" "NM_194429;NM_007045" ENSP00000230248 known 1 0 0 Eukaryotes 23 1 Cell cycle,Regulation of intracellular processes and metabolism 21 chr6 167412901 167453463 CGC myeloma,non-hodgkin lymphoma FGFR2 2263 fibroblast growth factor receptor 2 10q26 1492 3689 176943 "NP_001138390;NP_001138388;NP_001138391;NP_075259;NP_001138389;NP_001138387;NP_001138385;NP_000132;NP_001138386" "NM_022974;NM_001144918;NM_022971;NM_001144916;NM_022975;NM_022973;NM_022976;NM_001144919;NM_022970;NM_023030;NM_001144917;NM_001144915;NM_022972;NM_001144913;NM_000141;NM_001144914;NM_023028" "ENSP00000351276;ENSP00000358052;ENSP00000358057;ENSP00000350166;ENSP00000348559;ENSP00000353262" known 1 0 0 Last Universal Common Ancestor 40 2 Cell cycle,Cellular metabolism,Cellular processes,Signal transduction 80 chr10 123239374 123353331 CGC,WES endometrium,lung,chronic lymphocytic leukemia FGFR3 2261 fibroblast growth factor receptor 3 4p16.3 624 3690 134934 "NP_075254;NP_000133;NP_001156685" "NM_022965;NM_000142;NM_001163213" "ENSP00000414914;ENSP00000339824;ENSP00000412903" known 1 0 0 Last Universal Common Ancestor 69 3 Cell cycle,Cell response to stimuli,Cellular metabolism,Cellular processes,Development,Signal transduction 62 chr4 1795662 1808986 CGC,WES,WGS bladder,lymphoma,myeloma,lung FGFR4 2264 fibroblast growth factor receptor 4 5q35.1-qter 625 3691 134935 "NP_998812;NP_002002;NP_075252" "NM_213647;NM_002011;NM_022963" "ENSP00000424960;ENSP00000377254;ENSP00000292408" candidate 0 0 0 Last Universal Common Ancestor 3 0 Cellular metabolism,Cellular processes,Signal transduction 20 chr5 176516604 176524674 HTMS lung FH 2271 fumarate hydratase 1q42.1 652 3700 136850 NP_000134 NM_000143 ENSP00000355518 known 0 1 0 Last Universal Common Ancestor 14 0 Cell cycle,Cellular metabolism,Multicellular activities,Regulation of intracellular processes and metabolism 107 chr1 241661131 241683022 CGC FHDC1 85462 FH2 domain containing 1 4q31.3 13888 29363 - NP_203751 NM_033393 ENSP00000260008 candidate 0 0 0 Eukaryotes 0 6 Cellular processes -1 chr4 153864210 153897872 WGS lymphoma FHIT 2272 fragile histidine triad gene 3p14.2 3096 3701 601153 "NP_002003;NP_001159715" "NM_002012;NM_001166243" "ENSP00000417557;ENSP00000418582" known 1 0 0 Last Universal Common Ancestor 15 0 Cell cycle,Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism 63 chr3 59737955 60522695 CGC salivary FIGNL1 63979 fidgetin-like 1 7p12.1 10958 13286 - "NP_001036227;NP_071399" "NM_001042762;NM_022116" "ENSP00000349356;ENSP00000378924" candidate 0 0 0 Last Universal Common Ancestor 3 1 Cellular metabolism,DNA/RNA metabolism and transcription -1 chr7 50512964 50514985 WGS prostate FIP1L1 81608 FIP1 like 1 (S. cerevisiae) 4q12 9646 19124 607686 "NP_112179;NP_001128409;NP_001128410" "NM_030917;NM_001134937;NM_001134938" "ENSP00000351383;ENSP00000302993;ENSP00000336752" known 1 0 0 Eukaryotes 19 1 DNA/RNA metabolism and transcription,Regulation of transcription 29 chr4 54244006 54325613 CGC idiopathic hypereosinophilic syndrome FKBP3 2287 FK506 binding protein 3, 25kDa 14q21.2 1743 3719 186947 NP_002004 NM_002013 ENSP00000379374 candidate 0 0 0 Last Universal Common Ancestor 22 2 Cellular metabolism,Cellular processes 97 chr14 45585404 45603659 WGS glioblastoma FLCN 201163 folliculin 17p11.2 6278 27310 607273 "NP_659434;NP_653207" "NM_144997;NM_144606" "ENSP00000373821;ENSP00000285071" known 0 1 0 Eukaryotes 7 4 Cell cycle,Regulation of intracellular processes and metabolism 44 chr17 17116972 17131451 CGC FLI1 2313 Friend leukemia virus integration 1 11q24.1-q24.3 1901 3749 193067 "NP_001161153;NP_002008" "NM_001167681;NM_002017" "ENSP00000339627;ENSP00000281428" known 1 0 0 Metazoans 17 5 Cellular metabolism,DNA/RNA metabolism and transcription,Development,Multicellular activities,Regulation of intracellular processes and metabolism,Regulation of transcription 67 chr11 128628010 128680880 CGC sarcoma FLJ25328 148231 uncharacterized LOC148231 19p13.12 8056 - - - "NM_152483;NR_024336;NR_024335" - candidate 0 0 -1 - 0 0 -1 -1 - 0 0 WGS breast FLJ27352 145788 uncharacterized LOC145788 15q21.3 - - - NP_001185713 NM_001198784 ENSP00000456337 known 1 0 0 - 0 0 -1 -1 chr15 55710421 55710765 CGC lymphoma FLNA 2316 filamin A, alpha Xq28 2060 3754 300017 "NP_001104026;NP_001447" "NM_001110556;NM_001456" "ENSP00000358866;ENSP00000416926" candidate 0 0 0 Eukaryotes 122 6 Cellular metabolism,Cellular processes,DNA/RNA metabolism and transcription,Development,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction 109 chrX 153577220 153599613 WES breast FLNB 2317 filamin B, beta 3p14.3 4543 3755 603381 "NP_001448;NP_001157790;NP_001157791;NP_001157789" "NM_001457;NM_001164318;NM_001164319;NM_001164317" "ENSP00000420213;ENSP00000415599;ENSP00000351339;ENSP00000295956" candidate 0 0 0 Eukaryotes 27 6 Cellular processes,Development,Signal transduction 90 chr3 57994292 58156486 WES breast FLNC 2318 filamin C, gamma 7q32-q35 18 3756 102565 "NP_001120959;NP_001449" "NM_001127487;NM_001458" "ENSP00000344002;ENSP00000327145" candidate 0 0 0 Eukaryotes 37 2 -1 87 chr7 128470692 128498574 WES,WGS breast,colorectal,prostate FLRT2 23768 fibronectin leucine rich transmembrane protein 2 14q24-q32 5312 3761 604807 NP_037363 NM_013231 ENSP00000332879 candidate 0 0 0 Eukaryotes 10 0 -1 81 chr14 86087859 86089838 WGS chronic lymphocytic leukemia FLT3 2322 fms-related tyrosine kinase 3 13q12 635 3765 136351 NP_004110 NM_004119 ENSP00000241453 known 1 0 0 Last Universal Common Ancestor 11 2 Cell cycle,Cellular metabolism,Cellular processes,Regulation of intracellular processes and metabolism,Signal transduction 48 chr13 28578192 28674647 CGC,HTMS,WES,WGS leukemia,breast,lung,ovarian,pancreas,prostate,acute myeloid leukemia FMN2 56776 formin 2 1q43 10449 14074 606373 NP_064450 NM_020066 ENSP00000318884 candidate 0 0 0 Eukaryotes 18 0 Cell cycle,Cellular processes,DNA/RNA metabolism and transcription,Development,Multicellular activities -1 chr1 240255410 240635753 WES,WGS gastric,kidney,pancreas,lymphoma FMNL3 91010 formin-like 3 12q13.12 17007 23698 - "NP_944489;NP_783863" "NM_198900;NM_175736" ENSP00000335655 candidate 0 0 0 Eukaryotes 4 3 Cellular processes -1 chr12 50039601 50100963 WES pancreas FN1 2335 fibronectin 1 2q34 626 3778 135600 "NP_997647;NP_997643;NP_997641;NP_002017;NP_473375;NP_997639" "NM_212482;NM_212478;NM_212476;NM_002026;NM_054034;NM_212474;NM_212475" "ENSP00000338200;ENSP00000398907;ENSP00000350534;ENSP00000348285;ENSP00000410422;ENSP00000346839" candidate 0 0 0 Last Universal Common Ancestor 512 3 Cell motility and interactions,Cell response to stimuli,Immune system response,Signal transduction 97 chr2 216226281 216300525 WES colorectal FNBP1 23048 formin binding protein 1 9q34 10446 17069 606191 NP_055848 NM_015033 ENSP00000413625 known 1 0 0 Eukaryotes 34 7 Cellular processes 102 chr9 132658118 132757237 CGC leukemia FOXA1 3169 forkhead box A1 14q12-q13 3801 5021 602294 NP_004487 NM_004496 ENSP00000250448 candidate 0 0 0 Opisthokonts 1 3 Cellular metabolism,DNA/RNA metabolism and transcription,Development,Regulation of intracellular processes and metabolism,Regulation of transcription 49 chr14 38060573 38064177 WES prostate FOXA2 3170 forkhead box A2 20p11 2618 5022 600288 "NP_710141;NP_068556" "NM_153675;NM_021784" "ENSP00000315955;ENSP00000366319" candidate 0 0 0 Opisthokonts 0 1 Cellular metabolism,DNA/RNA metabolism and transcription,Multicellular activities,Regulation of intracellular processes and metabolism,Regulation of transcription 38 chr20 22562491 22564916 WGS lymphoma FOXE1 2304 forkhead box E1 (thyroid transcription factor 2) 9q22 6188 3806 602617 NP_004464 NM_004473 ENSP00000364265 candidate 0 0 0 Eukaryotes 1 1 Cell motility and interactions,Cellular metabolism,DNA/RNA metabolism and transcription,Development,Multicellular activities,Regulation of intracellular processes and metabolism,Regulation of transcription 17 chr9 100616197 100617315 WES lung FOXI1 2299 forkhead box I1 5q34 3057 3815 601093 "NP_036320;NP_658982" "NM_012188;NM_144769" "ENSP00000304286;ENSP00000415483" candidate 0 0 0 Eukaryotes 2 1 Cell response to stimuli,Cellular metabolism,DNA/RNA metabolism and transcription,Development,Regulation of intracellular processes and metabolism,Regulation of transcription 35 chr5 169532962 169535612 WGS breast FOXL2 668 forkhead box L2 3q23 5723 1092 605597 NP_075555 NM_023067 ENSP00000333188 known 1 0 0 Eukaryotes 5 0 Cell cycle,Cellular metabolism,Cellular processes,DNA/RNA metabolism and transcription,Development,Multicellular activities,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction 13 chr3 138664437 138665564 CGC ovarian FOXO1 2308 forkhead box O1 13q14.1 645 3819 136533 NP_002006 NM_002015 ENSP00000368880 known 1 0 0 Eukaryotes 51 12 Cell cycle,Cellular metabolism,DNA/RNA metabolism and transcription,Development,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction 98 chr13 41133663 41240349 CGC,WES,WGS sarcoma,non-hodgkin lymphoma,lymphoma FOXO3 2309 forkhead box O3 6q21 4061 3821 602681 "NP_963853;NP_001446" "NM_201559;NM_001455" "ENSP00000385824;ENSP00000339527" known 1 0 1 Eukaryotes 22 10 Cell cycle,Cellular metabolism,DNA/RNA metabolism and transcription,Development,Multicellular activities,Regulation of intracellular processes and metabolism,Regulation of transcription 108 chr6 108882412 108986055 CGC leukemia FOXO4 4303 forkhead box O4 Xq13.1 2070 7139 300033 "NP_001164402;NP_005929" "NM_001170931;NM_005938" ENSP00000363377 known 1 0 0 Eukaryotes 22 1 Cell cycle,Cellular metabolism,DNA/RNA metabolism and transcription,Development,Multicellular activities,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction 27 chrX 70316379 70321589 CGC leukemia FOXP1 27086 forkhead box P1 3p14.1 18518 3823 605515 "NP_001231737;NP_001231745;NP_001012523;NP_001231742;NP_001231739;NP_001231743;NP_001231741;NP_116071;NP_001231744" "NM_001244808;NM_001244816;NM_001012505;NM_001244813;NM_001244810;NM_001244814;NM_001244812;NM_032682;NM_001244815" "ENSP00000318721;ENSP00000318902" known 1 0 0 Metazoans 14 7 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription -1 chr3 71008401 71247532 CGC leukemia FOXRED2 80020 FAD-dependent oxidoreductase domain containing 2 22q12.3 8666 26264 613777 "NP_001095841;NP_079231" "NM_001102371;NM_024955" ENSP00000380401 candidate 0 0 0 Last Universal Common Ancestor 7 3 -1 3 chr22 36886058 36902469 WGS lung FRAS1 80144 Fraser syndrome 1 4q21.21 6382 19185 607830 "NP_079350;NP_001159605" "NM_025074;NM_032863;NM_206841;NM_020875;NM_001166133" ENSP00000326330 candidate 0 0 0 Last Universal Common Ancestor 1 3 -1 51 chr4 78979164 79462275 WGS melanoma FREM1 158326 FRAS1 related extracellular matrix 1 9p22.3 9865 23399 608944 "NP_001171175;NP_659403" "NM_001177704;NM_144966" ENSP00000412940 candidate 0 0 0 Last Universal Common Ancestor 3 1 -1 -1 chr9 14737397 14868975 WES breast FREM2 341640 FRAS1 related extracellular matrix protein 2 13q13.3 10602 25396 608945 NP_997244 NM_207361 ENSP00000280481 candidate 0 0 0 Last Universal Common Ancestor 8 1 Cell motility and interactions -1 chr13 39261482 39454921 WGS acute myeloid leukemia,lymphoma,prostate FRG2C 100288801 FSHD region gene 2 family, member C 3p12.3 - 33626 - NP_001118231 NM_001124759 ENSP00000312299 candidate 0 0 3 Mammals 0 0 -1 -1 chr3 75713531 75715189 WGS lymphoma FRMPD4 9758 FERM and PDZ domain containing 4 Xp22.2 10011 29007 300838 NP_055543 NM_014728 ENSP00000370057 candidate 0 0 0 Metazoans 5 0 -1 16 chrX 12157091 12736908 WES glioblastoma FRS2 10818 fibroblast growth factor receptor substrate 2 12q15 6372 16971 607743 "NP_006645;NP_001036020" "NM_006654;NM_001042555" "ENSP00000381083;ENSP00000299293" candidate 0 0 0 Eukaryotes 29 9 Cell cycle,Cellular metabolism,Cellular processes,Development,Other,Regulation of intracellular processes and metabolism,Signal transduction 6 chr12 69962811 69968732 HTMS breast,lung,ovarian,pancreas,prostate FSCB 84075 fibrous sheath CABYR binding protein 14q21.2 12638 20494 611779 NP_115511 NM_032135 ENSP00000344579 candidate 0 0 0 Last Universal Common Ancestor 0 2 -1 -1 chr14 44973716 44976190 WES breast,gastric FSIP2 401024 fibrous sheath interacting protein 2 2q32.1 13483 21675 - NP_775922 "NM_173651;NM_207482" ENSP00000344403 candidate 0 0 0 Mammals 1 0 -1 -1 chr2 186603355 186697950 WGS chronic lymphocytic leukemia FSTL3 10272 follistatin-like 3 (secreted glycoprotein) 19p13 5632 3973 605343 NP_005851 NM_005860 ENSP00000166139 known 1 0 0 Eukaryotes 19 8 Regulation of intracellular processes and metabolism,Signal transduction 81 chr19 676424 681705 CGC leukemia FSTL5 56884 follistatin-like 5 4q32.3 10998 21386 - "NP_001121899;NP_001121900;NP_064501" "NM_001128427;NM_001128428;NM_020116" "ENSP00000368462;ENSP00000305334" candidate 0 0 0 Eukaryotes 1 0 -1 -1 chr4 162306902 163032548 WES chronic lymphocytic leukemia FTCD 10841 formiminotransferase cyclodeaminase 21q22.3 8430 3974 606806 "NP_006648;NP_996848" "NM_006657;NM_206965" "ENSP00000291670;ENSP00000380854" candidate 0 0 0 Last Universal Common Ancestor 0 1 Cellular metabolism 30 chr21 47556904 47575437 WES lymphoma FUBP1 8880 far upstream element (FUSE) binding protein 1 1p31.1 10349 4004 603444 NP_003893 NM_003902 ENSP00000359804 known 0 1 0 Eukaryotes 52 6 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription 102 chr1 78414840 78444688 CGC,WES oligodendroglioma,chronic lymphocytic leukemia FUK 197258 fucokinase 16q22.1 16365 29500 608675 NP_659496 NM_145059 ENSP00000288078 candidate 0 0 0 Last Universal Common Ancestor 1 0 Cellular metabolism -1 chr16 70497094 70513580 WES pancreas FUS 2521 fused in sarcoma 16p11.2 660 4010 137070 "NP_004951;NP_001164105;NP_001164408" "NM_004960;NM_001170634;NR_028388;NM_001170937;NM_001010850" - known 1 0 0 Eukaryotes 99 1 DNA/RNA metabolism and transcription,Regulation of transcription 109 chr16 31193832 31202432 CGC histiocytoma,leukemia,sarcoma FUT9 10690 fucosyltransferase 9 (alpha (1,3) fucosyltransferase) 6q16 6036 4020 606865 NP_006572 NM_006581 - candidate 0 0 0 Last Universal Common Ancestor 1 1 Cellular metabolism,Cellular processes 41 chr6 96651032 96652108 WGS chronic lymphocytic leukemia FZD3 7976 frizzled family receptor 3 8p21 5849 4041 606143 "NP_665873;NP_059108" "NM_145866;NM_017412" ENSP00000240093 candidate 0 0 0 Eukaryotes 14 2 Development,Signal transduction 44 chr8 28360531 28420525 WES colorectal (hypermutated) G3BP1 10146 GTPase activating protein (SH3 domain) binding protein 1 5q33.1 6569 30292 608431 "NP_938405;NP_005745" "NM_198395;NM_005754" ENSP00000348578 candidate 0 0 1 Eukaryotes 53 7 Signal transduction 106 chr5 151166182 151183649 WES melanoma GAB1 2549 GRB2-associated binding protein 1 4q31.21 5116 4066 604439 "NP_997006;NP_002030" "NM_207123;NM_002039" ENSP00000262995 candidate 0 0 0 Last Universal Common Ancestor 17 0 Cell motility and interactions,Cellular metabolism,Cellular processes,Regulation of intracellular processes and metabolism,Signal transduction 35 chr4 144258342 144390339 WES breast GABBR1 2550 gamma-aminobutyric acid (GABA) B receptor, 1 6p21.31 4644 4070 603540 "NP_068704;NP_001461;NP_068703" "NM_021905;NM_021904;NM_001470;NM_021903" "ENSP00000366233;ENSP00000366211;ENSP00000366215" candidate 0 0 0 Last Universal Common Ancestor 19 2 Cellular metabolism,Cellular processes,Regulation of intracellular processes and metabolism,Signal transduction 74 chr6 29571323 29600162 WGS liver GABRA1 2554 gamma-aminobutyric acid (GABA) A receptor, alpha 1 5q34 662 4075 137160 "NP_001121118;NP_001121115;NP_001121116;NP_001121120;NP_000797;NP_001121117;NP_001121119" "NM_001127646;NM_001127643;NM_001127644;NM_001127648;NM_000806;NM_001127645;NM_001127647" "ENSP00000393097;ENSP00000415441" candidate 0 0 2 Metazoans 0 1 Cellular processes,Signal transduction 20 chr5 161277817 161324425 WES lymphoma GABRB3 2562 gamma-aminobutyric acid (GABA) A receptor, beta 3 15q11.2-q12 8844 4083 137192 "NP_001178250;NP_001178249;NP_068712;NP_000805" "NM_001191321;NM_001191320;NM_021912;NM_000814" "ENSP00000308725;ENSP00000442408" candidate 0 0 2 Eukaryotes 0 1 Cellular processes,Multicellular activities,Signal transduction 29 chr15 26792943 27018109 WGS liver GABRG1 2565 gamma-aminobutyric acid (GABA) A receptor, gamma 1 4p12 15923 4086 137166 NP_775807 NM_173536 ENSP00000295452 candidate 0 0 0 Metazoans 1 0 Cellular processes,Multicellular activities,Signal transduction -1 chr4 46043008 46125930 WGS medulloblastoma GALNS 2588 galactosamine (N-acetyl)-6-sulfate sulfatase 16q24.3 8357 4122 612222 NP_000503 NM_000512 ENSP00000268695 candidate 0 0 0 Last Universal Common Ancestor 0 0 Cellular metabolism 61 chr16 88880850 88923285 WES colorectal GALNT13 114805 UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 13 (GalNAc-T13) 2q24.1 16325 23242 608369 NP_443149 NM_052917 ENSP00000376570 candidate 0 0 1 Eukaryotes 4 0 -1 -1 chr2 154801011 155307060 WES pancreas GALNT5 11227 UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 5 (GalNAc-T5) 2q24.1 9970 4127 - NP_055383 NM_014568 - candidate 0 0 0 Eukaryotes 0 1 Cellular metabolism -1 chr2 158114595 158167857 WES breast GALNTL6 442117 UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase-like 6 4q34.1 - 33844 - NP_001030017 NM_001034845 - candidate 0 0 0 Last Universal Common Ancestor 0 0 -1 -1 chr4 172735732 173961248 WES breast GARS 2617 glycyl-tRNA synthetase 7p15 2617 4162 600287 NP_002038 NM_002047 ENSP00000373918 candidate 0 0 0 Last Universal Common Ancestor 30 2 Cellular metabolism,Cellular processes,DNA/RNA metabolism and transcription,Regulation of transcription 98 chr7 30634538 30673473 WGS lung GAS7 8522 growth arrest-specific 7 17p13.1 16011 4169 603127 "NP_001124303;NP_958836;NP_958839;NP_003635" "NM_001130831;NM_201432;NM_201433;NM_003644" "ENSP00000410108;ENSP00000379421" known 1 0 0 Eukaryotes 36 2 Cell cycle,Development 92 chr17 9820548 10101707 CGC leukemia GATA1 2623 GATA binding protein 1 (globin transcription factor 1) Xp11.23 2372 4170 305371 NP_002040 NM_002049 ENSP00000365858 known 1 0 0 Eukaryotes 52 1 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription 13 chrX 48649517 48652568 CGC leukemia GATA2 2624 GATA binding protein 2 3q21.3 673 4171 137295 "NP_116027;NP_001139134;NP_001139133" "NM_032638;NM_001145662;NM_001145661" ENSP00000345681 known 1 0 0 Eukaryotes 30 1 Cell cycle,Cellular metabolism,Cellular processes,DNA/RNA metabolism and transcription,Development,Regulation of intracellular processes and metabolism,Regulation of transcription 82 chr3 128199865 128205874 CGC,WES leukemia GATA3 2625 GATA binding protein 3 10p15 572 4172 131320 "NP_001002295;NP_002042" "NM_001002295;NM_002051" "ENSP00000368632;ENSP00000341619" known 0 1 0 Eukaryotes 19 3 Cell response to stimuli,Cellular metabolism,DNA/RNA metabolism and transcription,Development,Multicellular activities,Regulation of intracellular processes and metabolism,Regulation of transcription 76 chr10 8097619 8115983 CGC,WES breast GATA6 2627 GATA binding protein 6 18q11.1-q11.2 9043 4174 601656 NP_005248 NM_005257 ENSP00000269216 known 0 0 0 Eukaryotes 11 16 Cellular metabolism,DNA/RNA metabolism and transcription,Development,Regulation of intracellular processes and metabolism,Regulation of transcription 30 chr18 19751106 19780783 CGC,Amplified GCOM1 145781 GRINL1A complex locus 1 15q21.3 8091 26424 614071 "NP_001018101;NP_001018100" "NM_001018094;NM_001018099;NM_001018096;NM_001018097;NM_001018098;NM_001018093;NM_001018091;NM_001018092;NM_001018090;NM_001018095" - candidate 0 0 0 Last Universal Common Ancestor 0 0 -1 36 chr15 57884233 58006874 WGS glioblastoma GCOM2 339970 GRINL1B complex locus 2, pseudogene 4q12 - 15712 608311 - - - candidate 0 0 -1 Last Universal Common Ancestor 1 0 -1 -1 - 0 0 WGS acute myeloid leukemia GDA 9615 guanine deaminase 9q21.13 8849 4212 139260 "NP_001229435;NP_001229436;NP_004284;NP_001229434" "NM_001242506;NM_001242507;NM_004293;NM_001242505" "ENSP00000436619;ENSP00000351170" candidate 0 0 0 Last Universal Common Ancestor 12 3 Development -1 chr9 74764476 74865717 WGS chronic lymphocytic leukemia gen-01 348654 Gen endonuclease homolog 1 (Drosophila) 2p24.2 8813 26881 612449 "NP_001123481;NP_872431" "NM_001130009;NM_182625" "ENSP00000370653;ENSP00000318977" candidate 0 0 0 Last Universal Common Ancestor 1 2 DNA/RNA metabolism and transcription -1 chr2 17941211 17963203 WES breast GGA1 26088 golgi-associated, gamma adaptin ear containing, ARF binding protein 1 22q13.31 12078 17842 606004 "NP_001166159;NP_001166158;NP_037497;NP_001001560;NP_001001561" "NM_001172688;NM_001172687;NM_013365;NM_001001560;NM_001001561" "ENSP00000321288;ENSP00000414387;ENSP00000385287;ENSP00000341344" candidate 0 0 0 Eukaryotes 39 0 Cellular processes 109 chr22 38010199 38028715 WES breast GHSR 2693 growth hormone secretagogue receptor 3q26.31 3541 4267 601898 "NP_004113;NP_940799" "NM_004122;NM_198407" ENSP00000395344 candidate 0 0 0 Metazoans 2 1 Cell cycle,Cell response to stimuli,Cellular metabolism,Cellular processes,Development,Immune system response,Multicellular activities,Regulation of intracellular processes and metabolism,Signal transduction 5 chr3 172162954 172166203 WGS prostate GIF 2694 gastric intrinsic factor (vitamin B synthesis) 11q13 2024 4268 609342 NP_005133 NM_005142 ENSP00000257248 candidate 0 0 0 Eukaryotes 4 0 Cellular processes 26 chr11 59596960 59612926 WGS liver GIGYF2 26058 GRB10 interacting GYF protein 2 2q37.1 11639 11960 612003 "NP_056390;NP_001096617;NP_001096618;NP_001096616" "NM_015575;NM_001103147;NM_001103148;NM_001103146" ENSP00000362667 candidate 0 0 0 Eukaryotes 41 1 -1 102 chr2 233599908 233721567 WES pancreas GJD4 219770 gap junction protein, delta 4, 40.1kDa 10p11.21 13103 23296 611922 NP_699199 NM_153368 ENSP00000315070 candidate 0 0 0 Vertebrates 1 0 -1 -1 chr10 35894496 35897551 WES colorectal GKN1 56287 gastrokine 1 2p13.3 16217 23217 606402 NP_062563 NM_019617 ENSP00000367172 candidate 0 0 0 Vertebrates 1 1 Cell cycle,Regulation of intracellular processes and metabolism 10 chr2 69201768 69207952 WES acute myeloid leukemia GLG1 2734 golgi glycoprotein 1 16q22.3 2855 4316 600753 "NP_001139139;NP_001139138;NP_036333" "NR_027264;NR_027265;NM_001145667;NM_001145666;NM_012201" - candidate 0 0 0 Last Universal Common Ancestor 8 3 -1 109 chr16 74485957 74640992 WGS lymphoma GLI1 2735 GLI family zinc finger 1 12q13.2-q13.3 1311 4317 165220 "NP_005260;NP_001161081;NP_001153517" "NM_005269;NM_001167609;NM_001160045" "ENSP00000437607;ENSP00000441006;ENSP00000228682" candidate 0 0 0 Last Universal Common Ancestor 17 5 Cell cycle,Cellular metabolism,DNA/RNA metabolism and transcription,Development,Multicellular activities,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction 24 chr12 57857475 57865841 WES,WGS breast,melanoma GLI3 2737 GLI family zinc finger 3 7p13 1313 4319 165240 NP_000159 NM_000168 ENSP00000379258 candidate 0 0 0 Last Universal Common Ancestor 3 0 Cell cycle,Cellular metabolism,Cellular processes,DNA/RNA metabolism and transcription,Development,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction 56 chr7 42003931 42262852 HTMS,WES breast,lung,ovarian,pancreas,prostate,colorectal GLIPR2 152007 GLI pathogenesis-related 2 9p13.3 6187 18007 607141 NP_071738 NM_022343 ENSP00000367196 candidate 0 0 0 Last Universal Common Ancestor 4 1 -1 -1 chr9 36147782 36162516 WES melanoma GLTSCR1 29998 glioma tumor suppressor candidate region gene 1 19q13.3 9296 4332 605690 NP_056526 NM_015711 ENSP00000379946 candidate 0 0 0 Eukaryotes 17 0 -1 37 chr19 48176832 48205669 WES pancreas GML 2765 glycosylphosphatidylinositol anchored molecule like protein 8q24.3 3844 4375 602370 NP_002057 NM_002066 ENSP00000220940 candidate 0 0 0 Mammals 0 0 Cell cycle,Regulation of intracellular processes and metabolism,Signal transduction 55 chr8 143921854 143928103 WES glioblastoma GMPS 8833 guanine monphosphate synthetase 3q24 10927 4378 600358 NP_003866 NM_003875 ENSP00000438199 known 1 0 0 Last Universal Common Ancestor 25 1 Cellular metabolism,DNA/RNA metabolism and transcription 88 chr3 155611307 155655478 CGC leukemia GNA11 2767 guanine nucleotide binding protein (G protein), alpha 11 (Gq class) 19p13.3 759 4379 139313 NP_002058 NM_002067 - known 1 0 3 Eukaryotes 23 0 Cellular metabolism,Cellular processes,Development,Multicellular activities,Regulation of intracellular processes and metabolism,Signal transduction 96 chr19 3094650 3121174 CGC melanoma GNA13 10672 guanine nucleotide binding protein (G protein), alpha 13 17q24.3 5100 4381 604406 NP_006563 NM_006572 - candidate 0 0 0 Eukaryotes 2 6 Cell motility and interactions,Development,Multicellular activities,Regulation of intracellular processes and metabolism,Signal transduction 12 chr17 63010378 63052711 WES,WGS lymphoma,non-hodgkin lymphoma GNA15 2769 guanine nucleotide binding protein (G protein), alpha 15 (Gq class) 19p13.3 760 4383 139314 NP_002059 NM_002068 ENSP00000262958 candidate 0 0 0 Eukaryotes 0 0 Cellular metabolism,Cellular processes,Regulation of intracellular processes and metabolism,Signal transduction 45 chr19 3136449 3163014 WES melanoma GNAQ 2776 guanine nucleotide binding protein (G protein), q polypeptide 9q21 2998 4390 600998 NP_002063 NM_002072 - known 1 0 3 Eukaryotes 70 4 Cell cycle,Cellular metabolism,Cellular processes,Development,Multicellular activities,Regulation of intracellular processes and metabolism,Signal transduction 104 chr9 80336242 80646151 CGC melanoma GNAS 2778 GNAS complex locus 20q13.3 761 4392 139320 "NP_536351;NP_001070957;NP_057676;NP_536350;NP_001070958;NP_000507;NP_001070956" "NM_080426;NM_001077489;NM_016592;NM_080425;NM_001077490;NM_000516;NR_003259;NM_001077488" "ENSP00000360126;ENSP00000346328;ENSP00000265620;ENSP00000360115;ENSP00000360141;ENSP00000360136" known 1 0 0 Last Universal Common Ancestor 55 1 Cell response to stimuli,Cellular processes,Regulation of intracellular processes and metabolism,Signal transduction 109 chr20 57428321 57485881 CGC,HTMS,WES pituitary,breast,lung,ovarian,pancreas,prostate,cholangiocarcinoma,colorectal GNAT1 2779 guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 1 3p21 8850 4393 139330 "NP_000163;NP_653082" "NM_000172;NM_144499" - candidate 0 0 2 Eukaryotes 4 0 Cell response to stimuli,Signal transduction 9 chr3 50229159 50232385 WES chronic lymphocytic leukemia GNB4 59345 guanine nucleotide binding protein (G protein), beta polypeptide 4 3q26.33 9973 20731 610863 NP_067642 NM_021629 - candidate 0 0 3 Last Universal Common Ancestor 24 7 Signal transduction -1 chr3 179119004 179143988 WGS melanoma GOLGA4 2803 golgin A4 3p22-p21.3 3941 4427 602509 "NP_001166184;NP_002069" "NM_001172713;NM_002078" "ENSP00000349305;ENSP00000354486" candidate 0 0 0 Last Universal Common Ancestor 7 2 Cellular processes 86 chr3 37285042 37396678 WGS breast GOLGA5 9950 golgin A5 14q 6079 4428 606918 NP_005104 NM_005113 ENSP00000163416 known 1 0 0 Eukaryotes 5 3 Cellular metabolism,Cellular processes 93 chr14 93263783 93305788 CGC thyroid GOLGA6L6 727832 golgin A6 family-like 6 15q11.2 - 37225 - NP_001138476 NM_001145004 - candidate 0 0 3 Last Universal Common Ancestor 0 0 -1 -1 chr15 20739500 20747023 WGS melanoma GOLGA7B 401647 golgin A7 family, member B 10q24.2 16579 31668 614189 NP_001010917 "NM_001010917;XR_110442;XR_111108" - candidate 0 0 0 Eukaryotes 0 0 -1 -1 chr10 99619215 99625454 WGS glioblastoma GOPC 57120 golgi-associated PDZ and coiled-coil motif containing 6q21 6024 17643 606845 "NP_065132;NP_001017408" "NM_020399;NM_001017408" "ENSP00000052569;ENSP00000357484" known 1 0 0 Eukaryotes 34 3 Cellular metabolism,Cellular processes,Regulation of intracellular processes and metabolism -1 chr6 117884420 117923451 CGC glioblastoma GPAM 57678 glycerol-3-phosphate acyltransferase, mitochondrial 10q25.2 3865 24865 602395 "NP_065969;NP_001231878" "NM_020918;NM_001244949" "ENSP00000265276;ENSP00000409242" candidate 0 0 0 Last Universal Common Ancestor 2 9 Cellular metabolism -1 chr10 113913311 113941542 WGS medulloblastoma GPC3 2719 glypican 3 Xq26.1 2074 4451 300037 "NP_004475;NP_001158089;NP_001158090;NP_001158091" "NM_004484;NM_001164617;NM_001164618;NM_001164619" "ENSP00000377836;ENSP00000359854" known 0 1 0 Metazoans 6 0 -1 53 chrX 132670155 133119476 CGC GPC5 2262 glypican 5 13q32 3902 4453 602446 NP_004457 NM_004466 ENSP00000366267 known 0 0 0 Metazoans 1 0 -1 19 chr13 92051301 92797241 CGC,Amplified GPC6 10082 glypican 6 13q32 5099 4454 604404 NP_005699 NM_005708 - candidate 0 0 0 Metazoans 3 0 -1 -1 chr13 93879710 95055468 WES,WGS colorectal (non-hypermutated),prostate GPCPD1 56261 glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) 20p12.3 10025 26957 614124 NP_062539 NM_019593 ENSP00000368305 candidate 0 0 1 Eukaryotes 45 0 Cellular metabolism -1 chr20 5528310 5585058 WGS chronic lymphocytic leukemia GPHB5 122876 glycoprotein hormone beta 5 14q23.2 17053 18055 609652 NP_660154 NM_145171 - candidate 0 0 0 Metazoans 1 2 -1 -1 chr14 63779645 63784563 WGS glioblastoma GPHN 10243 gephyrin 14q23.3 4893 15465 603930 "NP_065857;NP_001019389" "NM_020806;NM_001024218" "ENSP00000312771;ENSP00000417901" known 1 0 0 Last Universal Common Ancestor 7 0 Cellular metabolism 57 chr14 66975246 67647651 CGC leukemia GPR112 139378 G protein-coupled receptor 112 Xq26.3 6578 18992 - NP_722576 NM_153834 ENSP00000377699 candidate 0 0 0 Last Universal Common Ancestor 0 1 Signal transduction -1 chrX 135390937 135496485 WES,WGS colorectal,lung GPR123 84435 G protein-coupled receptor 123 10q26 17058 13838 612302 NP_001077378 "NM_032422;NM_001083909" ENSP00000376384 candidate 0 0 0 Eukaryotes 0 3 Signal transduction -1 chr10 134910478 134943012 WGS acute myeloid leukemia GPR133 283383 G protein-coupled receptor 133 12q24.33 17061 19893 613639 NP_942122 NM_198827 ENSP00000261654 candidate 0 0 0 Eukaryotes 0 0 Signal transduction -1 chr12 131439011 131623805 WES pancreas GPR158 57512 G protein-coupled receptor 158 10p12.1 13601 23689 - NP_065803 NM_020752 ENSP00000365529 candidate 0 0 0 Metazoans 3 0 Signal transduction -1 chr10 25464350 25888200 WES colorectal GPR174 84636 G protein-coupled receptor 174 Xq21.1 6512 30245 - NP_115942 NM_032553 ENSP00000276077 candidate 0 0 0 Vertebrates 0 0 Signal transduction -1 chrX 78426505 78427503 WES head and neck squamous cell carcinoma GPR183 1880 G protein-coupled receptor 183 13q32.3 12040 3128 605741 NP_004942 NM_004951 ENSP00000365596 candidate 0 0 0 Vertebrates 3 1 Signal transduction 31 chr13 99947317 99948399 WGS acute myeloid leukemia GPR32 2854 G protein-coupled receptor 32 19q13.33 4430 4487 603195 NP_001497 NM_001506 ENSP00000270590 candidate 0 0 1 Mammals 0 0 Signal transduction 27 chr19 51273858 51274925 WES breast GPR84 53831 G protein-coupled receptor 84 12q13.13 16213 4535 606383 NP_065103 NM_020370 ENSP00000267015 candidate 0 0 0 Metazoans 6 0 Signal transduction -1 chr12 54756448 54757635 HTMS breast,lung,ovarian,pancreas,prostate GPRIN2 9721 G protein regulated inducer of neurite outgrowth 2 10q11.22 13804 23730 611240 NP_055511 NM_014696 - candidate 0 0 0 Metazoans 16 1 -1 52 chr10 46998881 47000254 WGS lymphoma GPS2 2874 G protein pathway suppressor 2 17p13 11878 4550 601935 NP_004480 NM_004489 ENSP00000370104 candidate 0 0 1 Eukaryotes 35 0 Regulation of intracellular processes and metabolism,Signal transduction 35 chr17 7216078 7218371 WES,WGS breast,medulloblastoma,lymphoma GPT 2875 glutamic-pyruvate transaminase (alanine aminotransferase) 8q24.3 689 4552 138200 NP_005300 NM_005309 ENSP00000378408 candidate 0 0 0 Last Universal Common Ancestor 1 0 Cellular metabolism 13 chr8 145729688 145732380 WGS lymphoma GRB10 2887 growth factor receptor-bound protein 10 7p12.2 3312 4564 601523 "NP_001001550;NP_001001549;NP_005302;NP_001001555" "NM_001001550;NM_001001549;NM_005311;NM_001001555" "ENSP00000381790;ENSP00000338543;ENSP00000381793" candidate 0 0 0 Eukaryotes 42 2 Signal transduction 98 chr7 50660652 50800019 HTMS breast,lung,ovarian,pancreas,prostate GRB2 2885 growth factor receptor-bound protein 2 17q24-q25 150 4566 108355 "NP_002077;NP_987102" "NM_002086;NM_203506" "ENSP00000339007;ENSP00000317360" candidate 0 0 0 Eukaryotes 1008 11 Signal transduction 96 chr17 73316452 73389709 WES lymphoma GRB7 2886 growth factor receptor-bound protein 7 17q12 3311 4567 601522 "NP_001229372;NP_001229371;NP_001025173;NP_005301" "NM_001242443;NM_001242442;NM_001030002;NM_005310" "ENSP00000377761;ENSP00000403459;ENSP00000377759;ENSP00000310771" known 0 0 0 Eukaryotes 61 2 Signal transduction 53 chr17 37898501 37903147 CGC,Amplified GREB1L 80000 growth regulation by estrogen in breast cancer-like 18q11.2 11161 31042 - NP_001136438 "NM_024935;NM_001142966" ENSP00000412060 candidate 0 0 0 Metazoans 51 1 -1 27 chr18 18963480 19102779 WGS breast GRHL2 79977 grainyhead-like 2 (Drosophila) 8q22.3 10545 2799 608576 NP_079191 NM_024915 ENSP00000251808 candidate 0 0 0 Opisthokonts 7 1 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription 59 chr8 102555470 102678928 WGS lymphoma GRIA1 2890 glutamate receptor, ionotropic, AMPA 1 5q33|5q31.1 695 4571 138248 "NP_000818;NP_001107655" "NM_000827;NM_001114183" "ENSP00000285900;ENSP00000428994" candidate 0 0 0 Metazoans 34 2 Cellular processes,Multicellular activities,Signal transduction 38 chr5 152870449 153190782 WGS melanoma GRIA3 2892 glutamate receptor, ionotrophic, AMPA 3 Xq25 2378 4573 305915 "NP_015564;NP_000819" "NM_007325;NM_000828;NM_181894" "ENSP00000264357;ENSP00000360311;ENSP00000360302" candidate 0 0 0 Metazoans 5 0 Cellular processes,Signal transduction 22 chrX 122318388 122616892 WES pancreas GRID1 2894 glutamate receptor, ionotropic, delta 1 10q22 17078 4575 610659 NP_060021 NM_017551 ENSP00000330148 candidate 0 0 0 Eukaryotes 0 0 Cellular processes -1 chr10 87362033 88126149 WES,WGS colorectal,glioblastoma GRIK3 2899 glutamate receptor, ionotropic, kainate 3 1p34-p33 691 4581 138243 NP_000822 NM_000831 ENSP00000362183 candidate 0 0 1 Eukaryotes 0 0 Cellular processes,Regulation of intracellular processes and metabolism,Signal transduction 0 chr1 37267455 37499709 WES lung GRIN2A 2903 glutamate receptor, ionotropic, N-methyl D-aspartate 2A 16p13.2 698 4585 138253 "NP_000824;NP_001127880;NP_001127879" "NM_000833;NM_001134408;NM_001134407" ENSP00000385872 candidate 0 0 0 Metazoans 29 1 Cellular processes,Development,Multicellular activities,Signal transduction 47 chr16 9857009 10274268 WES melanoma GRIN2D 2906 glutamate receptor, ionotropic, N-methyl D-aspartate 2D 19q13.1-qter 4095 4588 602717 NP_000827 NM_000836 ENSP00000263269 candidate 0 0 0 Metazoans 2 1 Cellular processes,Signal transduction 9 chr19 48901650 48947191 WES breast GRIN3B 116444 glutamate receptor, ionotropic, N-methyl-D-aspartate 3B 19p13.3 - 16768 606651 "XP_003403748;NP_619635" "XM_003403700;NM_138690" ENSP00000234389 candidate 0 0 0 Metazoans 3 0 Cellular processes,Regulation of intracellular processes and metabolism -1 chr19 996384 1009598 WGS lymphoma GRM1 2911 glutamate receptor, metabotropic 1 6q24 5129 4593 604473 "NP_001107801;NP_000829" "NM_001114329;NM_000838" "ENSP00000354896;ENSP00000376119" candidate 0 0 0 Metazoans 16 3 Multicellular activities,Signal transduction 50 chr6 146350654 146755929 HTMS,WES breast,lung,ovarian,pancreas,prostate,colorectal GRM3 2913 glutamate receptor, metabotropic 3 7q21.1-q21.2 3070 4595 601115 NP_000831 NM_000840 ENSP00000355316 candidate 0 0 1 Metazoans 7 1 Multicellular activities,Regulation of intracellular processes and metabolism,Signal transduction 40 chr7 86394462 86493668 HTMS,WES,WGS breast,lung,ovarian,pancreas,prostate,glioblastoma,chronic lymphocytic leukemia GRM5 2915 glutamate receptor, metabotropic 5 11q14.3 - 4597 604102 "NP_000833;NP_001137303" "NM_000842;NM_001143831" "ENSP00000405690;ENSP00000402912" candidate 0 0 0 Metazoans 17 1 Multicellular activities,Signal transduction 29 chr11 88241763 88781040 WGS prostate GRM8 2918 glutamate receptor, metabotropic 8 7q31.3-q32.1 3071 4600 601116 "NP_000836;NP_001120795" "NM_000845;NM_001127323;NR_028041" "ENSP00000409790;ENSP00000351142" candidate 0 0 2 Metazoans 4 1 Cell response to stimuli,Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction 32 chr7 126079176 126883258 HTMS,WES breast,lung,ovarian,pancreas,prostate,head and neck squamous cell carcinoma GRXCR2 643226 glutaredoxin, cysteine rich 2 5q32 - 33862 - NP_001073985 NM_001080516 ENSP00000367214 candidate 0 0 0 Eukaryotes 0 0 -1 -1 chr5 145239299 145252531 WGS melanoma GSK3B 2932 glycogen synthase kinase 3 beta 3q13.3 5418 4617 605004 "NP_002084;NP_001139628" "NM_002093;NM_001146156" ENSP00000264235 candidate 0 0 1 Last Universal Common Ancestor 327 2 Cell cycle,Cellular metabolism,Cellular processes,Development,Regulation of intracellular processes and metabolism,Signal transduction 92 chr3 119545638 119812281 HTMS breast,lung,ovarian,pancreas,prostate GSN 2934 gelsolin 9q33 674 4620 137350 "NP_001121134;NP_001121138;NP_000168;NP_001121136;NP_001121135;NP_001121137;NP_001121139;NP_937895" "NM_001127662;NM_001127666;NM_000177;NM_001127664;NM_001127663;NM_001127665;NM_001127667;NM_198252" "ENSP00000362924;ENSP00000362914;ENSP00000416586;ENSP00000411293;ENSP00000377882;ENSP00000340888" candidate 0 0 0 Eukaryotes 56 4 Cellular metabolism,Cellular processes,Regulation of intracellular processes and metabolism 104 chr9 124062140 124094878 WES breast GSTCD 79807 glutathione S-transferase, C-terminal domain containing 4q24 7823 25806 - "NP_079027;NP_001026890" "NM_024751;NM_001031720" "ENSP00000378216;ENSP00000378218" candidate 0 0 0 Last Universal Common Ancestor 1 2 -1 41 chr4 106638771 106766731 WGS breast GTF3C3 9330 general transcription factor IIIC, polypeptide 3, 102kDa 2q33.1 11997 4666 604888 "NP_036218;NP_001193703" "NM_012086;NM_001206774" "ENSP00000386465;ENSP00000263956" candidate 0 0 0 Eukaryotes 18 3 Cellular metabolism,DNA/RNA metabolism and transcription 62 chr2 197629290 197664335 WGS breast GTPBP2 54676 GTP binding protein 2 6p21 8465 4670 607434 NP_061969 NM_019096 ENSP00000303997 candidate 0 0 0 Last Universal Common Ancestor 169 0 Signal transduction 55 chr6 43589354 43596899 WGS liver GUCY1A2 2977 guanylate cyclase 1, soluble, alpha 2 11q21-q22 3146 4684 601244 "NP_001243353;NP_000846" "NM_001256424;NM_000855" - candidate 0 0 0 Last Universal Common Ancestor 10 1 Cellular metabolism,DNA/RNA metabolism and transcription,Signal transduction 23 chr11 106558278 106888781 WES colorectal,pancreas GUK1 2987 guanylate kinase 1 1q32-q41 755 4693 139270 "NP_001229769;NP_001152863;NP_001229768;NP_000849;NP_001152862" "NM_001242840;NM_001159391;NM_001242839;NM_000858;NM_001159390" "ENSP00000317659;ENSP00000375738;ENSP00000355677;ENSP00000355689" candidate 0 0 0 Last Universal Common Ancestor 3 3 Cellular metabolism,DNA/RNA metabolism and transcription 107 chr1 228328004 228336550 WGS breast GXYLT1 283464 glucoside xylosyltransferase 1 12q12 - 27482 613321 "NP_001093120;NP_775872" "NM_001099650;NM_173601" ENSP00000381666 candidate 0 0 4 Last Universal Common Ancestor 5 5 Cellular metabolism -1 chr12 42481591 42538448 WGS liver,lymphoma H1FOO 132243 H1 histone family, member O, oocyte-specific 3q22.1 13621 18463 - NP_722575 NM_153833 ENSP00000319799 candidate 0 0 1 Eukaryotes 0 0 Cell cycle,DNA/RNA metabolism and transcription -1 chr3 129262062 129270180 WES lymphoma H3F3A 3020 H3 histone, family 3A 1q42.12 3082 4764 601128 NP_002098 NM_002107 ENSP00000355780 known 1 0 36 Last Universal Common Ancestor 71 1 -1 36 chr2 175584636 175585043 CGC,WES glioma,glioblastoma H3F3C 440093 H3 histone, family 3C 12p11.21 18443 33164 - NP_001013721 NM_001013699 ENSP00000339835 candidate 0 0 33 Last Universal Common Ancestor 3 2 DNA/RNA metabolism and transcription -1 chr12 31944696 31945100 WES head and neck squamous cell carcinoma H6PD 9563 hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase) 1p36 681 4795 138090 NP_004276 NM_004285 ENSP00000366620 candidate 0 0 0 Last Universal Common Ancestor 1 4 Cellular metabolism,DNA/RNA metabolism and transcription 52 chr1 9304994 9324925 WGS prostate HAPLN1 1404 hyaluronan and proteoglycan link protein 1 5q14.3 275 2380 115435 NP_001875 NM_001884 ENSP00000274341 candidate 0 0 0 Eukaryotes 9 2 -1 8 chr5 82937318 82969342 WES colorectal HARS 3035 histidyl-tRNA synthetase 5q31.3 827 4816 142810 NP_002100 NM_002109 "ENSP00000411511;ENSP00000387893;ENSP00000304668" candidate 0 0 0 Last Universal Common Ancestor 17 6 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of transcription 91 chr5 140053845 140070889 WGS lymphoma HAS1 3036 hyaluronan synthase 1 19q13.4 3271 4818 601463 NP_001514 NM_001523 ENSP00000222115 candidate 0 0 0 Last Universal Common Ancestor 6 0 Cellular metabolism 13 chr19 52216683 52223154 WGS lymphoma HAUS3 79441 HAUS augmin-like complex, subunit 3 4p16.3 10784 28719 613430 NP_078787 NM_024511 ENSP00000243706 candidate 0 0 0 Eukaryotes 6 7 -1 29 chr4 2233657 2242673 WGS breast HCN1 348980 hyperpolarization activated cyclic nucleotide-gated potassium channel 1 5p12 9099 4845 602780 NP_066550 NM_021072 - candidate 0 0 0 Last Universal Common Ancestor 4 0 Cellular processes -1 chr5 45262026 45696195 WES lung HCN4 10021 hyperpolarization activated cyclic nucleotide-gated potassium channel 4 15q24.1 9240 16882 605206 NP_005468 NM_005477 ENSP00000261917 candidate 0 0 0 Last Universal Common Ancestor 2 6 Cellular processes,Development,Multicellular activities 18 chr15 73614825 73660611 WGS liver HDAC2 3066 histone deacetylase 2 6q21 5521 4853 605164 NP_001518 "NM_001527;NR_033441" ENSP00000381331 candidate 0 0 1 Last Universal Common Ancestor 73 3 Cellular metabolism,Cellular processes,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription 93 chr6 114262871 114292072 WGS melanoma HDAC4 9759 histone deacetylase 4 2q37.3 5610 14063 605314 NP_006028 NM_006037 ENSP00000264606 candidate 0 0 0 Last Universal Common Ancestor 25 10 Cell cycle,Cellular metabolism,DNA/RNA metabolism and transcription,Development,Immune system response,Regulation of intracellular processes and metabolism,Regulation of transcription 54 chr2 239975155 240158364 WES breast HDAC9 9734 histone deacetylase 9 7p21.1 5944 14065 606543 "NP_478056;NP_001191074;NP_001191075;NP_001191077;NP_848512;NP_055522;NP_848510;NP_001191076;NP_001191073" "NM_058177;NM_058176;NM_001204145;NM_001204146;NM_001204148;NM_178425;NM_014707;NM_178423;NM_001204147;NM_001204144" "ENSP00000384017;ENSP00000384382;ENSP00000410337;ENSP00000384657" candidate 0 0 0 Last Universal Common Ancestor 87 0 Cellular metabolism,Cellular processes,DNA/RNA metabolism and transcription,Development,Immune system response,Regulation of intracellular processes and metabolism,Regulation of transcription 54 chr7 18624897 19015577 WGS prostate HDLBP 3069 high density lipoprotein binding protein 2q37.3 813 4857 142695 "NP_005327;NP_001230829;NP_976221" "NM_005336;NM_001243900;NM_203346" ENSP00000375836 candidate 0 0 0 Eukaryotes 43 4 Cellular metabolism,Cellular processes 104 chr2 242169019 242206284 WES breast HEATR4 399671 HEAT repeat containing 4 14q24.3 14657 16761 - "NP_976054;NP_001207413" "NM_203309;NM_001220484" "ENSP00000450444;ENSP00000335447" candidate 0 0 0 Eukaryotes 1 0 -1 -1 chr14 73945314 73989856 WGS glioblastoma HELB 92797 helicase (DNA) B 12q14.3 9979 17196 - NP_387467 NM_033647 ENSP00000443287 candidate 0 0 0 Last Universal Common Ancestor 5 0 Cellular metabolism,DNA/RNA metabolism and transcription -1 chr12 66696384 66731879 WGS melanoma HERC2 8924 hect domain and RLD 2 15q13 6905 4868 605837 NP_004658 NM_004667 ENSP00000261609 candidate 0 0 0 Eukaryotes 60 3 Cellular metabolism,Cellular processes 69 chr15 28356912 28566579 WGS lung HERPUD1 9709 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 16q13 7456 13744 608070 "NP_001010990;NP_055500;NP_001010989" "NM_001010990;NM_014685;NM_001010989" "ENSP00000300302;ENSP00000409555" known 1 0 0 Eukaryotes 36 4 Cell response to stimuli,Cellular metabolism,Cellular processes 108 chr16 56966157 56977199 CGC prostate HEY1 23462 hairy/enhancer-of-split related with YRPW motif 1 8q21 4260 4880 602953 "NP_036390;NP_001035798" "NM_012258;NM_001040708" "ENSP00000338272;ENSP00000346761" known 1 0 0 Opisthokonts 8 2 Cellular metabolism,DNA/RNA metabolism and transcription,Development,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction 95 chr8 80677426 80679898 CGC sarcoma HINFP 25988 histone H4 transcription factor 11q23.3 7387 17850 607099 "NP_945322;NP_056332;NP_001230188" "NM_198971;NM_015517;NM_001243259" - candidate 0 0 0 Metazoans 1 0 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription 10 chr11 118997655 119005205 WES pancreas HIP1 3092 huntingtin interacting protein 1 7q11.23 3461 4913 601767 "NP_005329;NP_001230127" "NM_005338;NM_001243198" "ENSP00000410300;ENSP00000336747" known 1 0 0 Eukaryotes 9 0 Cell cycle,Cellular processes,Regulation of intracellular processes and metabolism,Signal transduction 53 chr7 75167496 75368238 CGC leukemia HIST1H1B 3009 histone cluster 1, H1b 6p22.1 821 4719 142711 NP_005313 NM_005322 ENSP00000330074 candidate 0 0 3 Eukaryotes 26 3 DNA/RNA metabolism and transcription,Development 7 chr6 27834630 27835307 WES colorectal HIST1H1C 3006 histone cluster 1, H1c 6p21.3 7514 4716 142710 NP_005310 NM_005319 ENSP00000339566 candidate 0 0 3 Eukaryotes 15 2 DNA/RNA metabolism and transcription 75 chr6 26056018 26056656 WES lymphoma,non-hodgkin lymphoma HIST1H1E 3008 histone cluster 1, H1e 6p21.3 7513 4718 142220 NP_005312 NM_005321 ENSP00000307705 candidate 0 0 3 Eukaryotes 11 1 DNA/RNA metabolism and transcription 2 chr6 26156619 26157275 WES lymphoma HIST1H2AL 8332 histone cluster 1, H2al 6p22.1 9103 4730 602793 NP_003502 NM_003511 ENSP00000349873 candidate 0 0 -1 Eukaryotes 14 1 -1 5 - 0 0 WES lymphoma HIST1H2BC 8347 histone cluster 1, H2bc 6p22.1 13656 4757 602847 NP_003517 NM_003526 - candidate 0 0 -1 Eukaryotes 22 2 Cell response to stimuli,DNA/RNA metabolism and transcription 20 - 0 0 WES breast,lymphoma HIST1H2BO 8348 histone cluster 1, H2bo 6p22.1 11904 4758 602808 NP_003518 NM_003527 ENSP00000303408 candidate 0 0 26 Eukaryotes 5 2 DNA/RNA metabolism and transcription 1 chr6 27861241 27861618 WES lymphoma HIST1H3B 8358 histone cluster 1, H3b 6p22.1 11913 4776 602819 NP_003528 NM_003537 ENSP00000244661 candidate 0 0 -1 Last Universal Common Ancestor 13 3 -1 5 - 0 0 WES lymphoma HIST1H4B 8366 histone cluster 1, H4b 6p22.1 11920 4789 602829 NP_003535 NM_003544 ENSP00000366581 candidate 0 0 -1 Last Universal Common Ancestor 0 1 -1 36 - 0 0 WGS liver HIST1H4H 8365 histone cluster 1, H4h 6p22.1 11919 4788 602828 NP_003534 NM_003543 ENSP00000366956 candidate 0 0 14 Last Universal Common Ancestor 14 5 -1 36 chr1 149804249 149804557 WES head and neck squamous cell carcinoma HIST1H4I 8294 histone cluster 1, H4i 6p21.33 9109 4793 602833 NP_003486 NM_003495 - known 1 0 14 Last Universal Common Ancestor 37 2 -1 36 chr1 149804249 149804557 CGC non-hodgkin lymphoma HK3 3101 hexokinase 3 (white cell) 5q35.2 806 4925 142570 NP_002106 NM_002115 ENSP00000292432 candidate 0 0 0 Last Universal Common Ancestor 3 0 Cellular metabolism 7 chr5 176308077 176323160 WGS chronic lymphocytic leukemia HLA-A 3105 major histocompatibility complex, class I, A 6p21.3 826 4931 142800 "NP_002107;NP_001229687" "NM_002116;NM_001242758" ENSP00000366005 candidate 0 0 8 Metazoans 54 8 Immune system response 109 chr6 29910331 29913057 WES,WGS lung,lymphoma,myeloma HLA-B 3106 major histocompatibility complex, class I, B 6p21.3 828 4932 142830 NP_005505 NM_005514 ENSP00000399168 candidate 0 0 6 Vertebrates 307 0 Immune system response 109 chr6 31322263 31324935 WES lymphoma HLA-DRB9 3132 major histocompatibility complex, class II, DR beta 9 (pseudogene) 6p21.3 - 4957 - - - - candidate 0 0 -1 - 0 0 -1 -1 - 0 0 WES glioblastoma HLF 3131 hepatic leukemia factor 17q22 797 4977 142385 NP_002117 NM_002126 ENSP00000226067 known 1 0 0 Metazoans 7 0 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription 69 chr17 53342846 53398237 CGC leukemia HMCN1 83872 hemicentin 1 1q25.3-q31.1 6509 19194 608548 NP_114141 NM_031935 ENSP00000271588 candidate 0 0 0 Last Universal Common Ancestor 2 1 Cell response to stimuli,Cellular metabolism,Cellular processes -1 chr1 185703912 186159007 WES chronic lymphocytic leukemia,pancreas HMGA1 3159 high mobility group AT-hook 1 6p21 2829 5010 600701 "NP_665910;NP_665908;NP_665912;NP_665906;NP_665909;NP_002122" "NM_145903;NM_145904;NM_145901;NM_145905;NM_145899;NM_145902;NM_002131" "ENSP00000385693;ENSP00000308227;ENSP00000399888;ENSP00000288245;ENSP00000363230" known 1 0 5 Mammals 58 10 Cellular metabolism,Cellular processes,DNA/RNA metabolism and transcription,Multicellular activities,Other,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction 69 chr12 110867767 110868087 CGC other,thyroid HMGA2 8091 high mobility group AT-hook 2 12q15 2827 5009 600698 "NP_003474;NP_003475" "NM_001015886;NM_003483;NM_003484" "ENSP00000384026;ENSP00000346658" known 1 0 0 Opisthokonts 20 16 Cell cycle,Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription 57 chr12 66219051 66357069 CGC leiomyoma,lipoma,salivary HMGB1 3146 high mobility group box 1 13q12 1228 4983 163905 NP_002119 NM_002128 - candidate 0 0 24 Eukaryotes 111 3 Cell cycle,Cellular metabolism,DNA/RNA metabolism and transcription,Development,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction 109 chr13 31035497 31037817 WES lymphoma HMGN2P46 283651 high mobility group nucleosomal binding domain 2 pseudogene 46 15q21.1 16622 26817 611314 - "NM_173609;NR_022014;NM_001005269;NM_001005268;NM_001005267;NM_001005266" - known 1 0 -1 - 1 0 -1 -1 - 0 0 CGC prostate HNF1A 6927 HNF1 homeobox A 12q22-qter|12q24.2 800 11621 142410 NP_000536 NM_000545 ENSP00000443112 known 0 1 0 Metazoans 12 0 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription 43 chr12 121416572 121438992 CGC,WES liver,breast HNF1B 6928 HNF1 homeobox B 17cen-q21.3 8926 11630 189907 "NP_000449;NP_001159395" "NM_000458;NM_001165923;NM_006481" ENSP00000225893 candidate 0 0 0 Eukaryotes 0 2 Cellular metabolism,DNA/RNA metabolism and transcription,Development,Regulation of intracellular processes and metabolism,Regulation of transcription 68 chr17 36059082 36104875 WES lymphoma HNRNPA2B1 3181 heterogeneous nuclear ribonucleoprotein A2/B1 7p15 2526 5033 600124 "NP_112533;NP_002128" "NM_031243;NM_002137" ENSP00000346694 known 1 0 0 Last Universal Common Ancestor 105 4 Cellular processes,DNA/RNA metabolism and transcription,Regulation of transcription 108 chr7 26232139 26237486 CGC prostate HNRNPU 3192 heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) 1q44 4185 5048 602869 "NP_114032;NP_004492" "NM_031844;NM_004501" ENSP00000393151 candidate 0 0 0 Eukaryotes 254 5 DNA/RNA metabolism and transcription,Regulation of transcription 109 chr1 245017755 245027609 WGS lymphoma HOOK3 84376 hook homolog 3 (Drosophila) 8p11.21 9699 23576 607825 NP_115786 NM_032410 - known 1 0 0 Eukaryotes 12 1 Cellular processes -1 chr8 42752275 42873638 CGC thyroid HOXA11 3207 homeobox A11 7p15.2 846 5101 142958 NP_005514 NM_005523 ENSP00000006015 known 1 0 0 Vertebrates 9 3 Cellular metabolism,DNA/RNA metabolism and transcription,Development,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction 30 chr7 27222418 27224763 CGC leukemia HOXA13 3209 homeobox A13 7p15.2 847 5102 142959 NP_000513 NM_000522 - known 1 0 0 Metazoans 7 3 Cellular metabolism,DNA/RNA metabolism and transcription,Development,Regulation of intracellular processes and metabolism,Regulation of transcription -1 chr7 27237820 27239696 CGC leukemia HOXA3 3200 homeobox A3 7p15.2 842 5104 142954 "NP_109377;NP_705895" "NM_030661;NM_153632;NM_153631" ENSP00000379640 candidate 0 0 0 Opisthokonts 0 11 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription 9 chr7 27147537 27150259 WES breast HOXA9 3205 homeobox A9 7p15.2 844 5109 142956 NP_689952 NM_152739 ENSP00000343619 known 1 0 0 Metazoans 18 12 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription 28 chr7 27203225 27205076 CGC leukemia HOXC11 3227 homeobox C11 12q13.3 9275 5123 605559 NP_055027 NM_014212 ENSP00000243082 known 1 0 0 Vertebrates 14 0 Cellular metabolism,DNA/RNA metabolism and transcription,Development,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction 56 chr12 54367026 54369194 CGC leukemia HOXC13 3229 homeobox C13 12q13.3 862 5125 142976 NP_059106 NM_017410 ENSP00000243056 known 1 0 0 Metazoans 9 1 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription 22 chr12 54332691 54339037 CGC leukemia HOXD11 3237 homeobox D11 2q31.1 869 5134 142986 NP_067015 NM_021192 - known 1 0 0 Vertebrates 2 0 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription 21 chr2 176972084 176973867 CGC leukemia HOXD13 3239 homeobox D13 2q31.1 872 5136 142989 NP_000514 NM_000523 ENSP00000376322 known 1 0 0 Vertebrates 7 2 Cell cycle,Cellular metabolism,DNA/RNA metabolism and transcription,Development,Regulation of intracellular processes and metabolism,Regulation of transcription 17 chr2 176957619 176959455 CGC leukemia HRAS 3265 v-Ha-ras Harvey rat sarcoma viral oncogene homolog 11p15.5 1813 5173 190020 "NP_789765;NP_005334;NP_001123914" "NM_176795;NM_005343;NM_001130442" "ENSP00000407586;ENSP00000309845;ENSP00000388246" known 1 0 2 Last Universal Common Ancestor 111 6 Cell motility and interactions,Development,Signal transduction 76 chr11 532639 534322 CGC,WES other,sarcoma,bladder,head and neck squamous cell carcinoma,lung,prostate HRC 3270 histidine rich calcium binding protein 19q13.3 818 5178 142705 NP_002143 NM_002152 ENSP00000252825 candidate 0 0 0 Opisthokonts 0 1 Multicellular activities 27 chr19 49655259 49658494 WGS lymphoma,prostate HRNR 388697 hornerin 1q21.3 17114 20846 - NP_001009931 NM_001009931 ENSP00000357791 candidate 0 0 3 Last Universal Common Ancestor 14 0 Development -1 chr1 152185555 152195729 WGS lymphoma HSP90AA1 3320 heat shock protein 90kDa alpha (cytosolic), class A member 1 14q32.33 777 5253 140571 "NP_001017963;NP_005339" "NM_001017963;NM_005348" "ENSP00000335153;ENSP00000216281" known 1 0 6 Last Universal Common Ancestor 412 3 Cell response to stimuli,Cellular metabolism,Cellular processes,Regulation of intracellular processes and metabolism,Signal transduction 108 chr14 102548052 102605741 CGC non-hodgkin lymphoma HSP90AB1 3326 heat shock protein 90kDa alpha (cytosolic), class B member 1 6p12 6763 5258 140572 NP_031381 NM_007355 ENSP00000360709 known 1 0 9 Last Universal Common Ancestor 580 1 Cell response to stimuli,Cellular metabolism,Cellular processes,Regulation of intracellular processes and metabolism 109 chr6 44216367 44221332 CGC non-hodgkin lymphoma HSPA2 3306 heat shock 70kDa protein 2 14q24.1 7174 5235 140560 NP_068814 NM_021979 ENSP00000247207 candidate 0 0 12 Last Universal Common Ancestor 8 2 Cell cycle,Cell response to stimuli,Development,Multicellular activities 85 chr14 65007568 65009484 WGS prostate HSPA5 3309 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) 9q33.3 682 5238 138120 NP_005338 NM_005347 ENSP00000324173 candidate 0 0 2 Last Universal Common Ancestor 234 3 -1 109 chr9 127998874 128003405 WGS prostate HTR1E 3354 5-hydroxytryptamine (serotonin) receptor 1E 6q14-q15 1635 5291 182132 NP_000856 NM_000865 ENSP00000307766 candidate 0 0 0 Metazoans 4 0 Multicellular activities,Signal transduction 16 chr6 87725053 87726147 WES gastric HYDIN 54768 HYDIN, axonemal central pair apparatus protein 16q22.2 11042 19368 610812 "NP_001185472;NP_060028;NP_001185471;NP_116210" "NM_001198543;NM_017558;NM_001198542;NM_032821" "ENSP00000444970;ENSP00000437341;ENSP00000377197;ENSP00000314736" candidate 0 0 0 Eukaryotes 1 0 -1 0 chr16 70841486 71220798 WES,WGS chronic lymphocytic leukemia,lung ICAM5 7087 intercellular adhesion molecule 5, telencephalin 19p13.2 3509 5348 601852 NP_003250 NM_003259 ENSP00000221980 candidate 0 0 0 Eukaryotes 13 4 -1 32 chr19 10400720 10407289 WES breast ICK 22858 intestinal cell (MAK-like) kinase 6p12.1 9996 21219 612325 "NP_055735;NP_057597" "NM_014920;NM_016513" "ENSP00000263043;ENSP00000349458" candidate 0 0 0 Last Universal Common Ancestor 11 4 Cellular metabolism,Cellular processes,Signal transduction 26 chr6 52869950 52906034 WGS lung ID3 3399 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein 1p36.13-p36.12 2608 5362 600277 NP_002158 NM_002167 ENSP00000363689 candidate 0 0 0 Vertebrates 42 5 Cell cycle,Cellular metabolism,DNA/RNA metabolism and transcription,Development,Regulation of intracellular processes and metabolism,Regulation of transcription 40 chr1 23885454 23885917 WES,WGS lymphoma IDH1 3417 isocitrate dehydrogenase 1 (NADP+), soluble 2q33.3 984 5382 147700 NP_005887 NM_005896 ENSP00000260985 known 1 0 1 Last Universal Common Ancestor 12 2 Cellular metabolism 98 chr2 209101806 209116275 CGC,WES,WGS glioblastoma,oligodendroglioma,prostate,acute myeloid leukemia IDH2 3418 isocitrate dehydrogenase 2 (NADP+), mitochondrial 15q26.1 973 5383 147650 NP_002159 NM_002168 - known 1 0 0 Last Universal Common Ancestor 4 2 Cellular metabolism 96 chr15 90627501 90645622 CGC glioblastoma IFIT3 3437 interferon-induced protein with tetratricopeptide repeats 3 10q24 5228 5411 604650 "NP_001026853;NP_001540" "NM_001031683;NM_001549" "ENSP00000360876;ENSP00000360883" candidate 0 0 0 Last Universal Common Ancestor 63 6 -1 54 chr10 91098416 91099882 WGS glioblastoma,medulloblastoma IGF2R 3482 insulin-like growth factor 2 receptor 6q26 928 5467 147280 NP_000867 NM_000876 ENSP00000349437 candidate 0 0 0 Eukaryotes 31 8 Cellular processes,Signal transduction 89 chr6 160390279 160526113 WES pancreas IGFBP3 3486 insulin-like growth factor binding protein 3 7p13-p12 899 5472 146732 "NP_000589;NP_001013416" "NM_000598;NM_001013398" ENSP00000275521 candidate 0 0 0 Vertebrates 36 5 Cell cycle,Cell motility and interactions,Cellular metabolism,Cellular processes,Development,Multicellular activities,Regulation of intracellular processes and metabolism,Signal transduction 95 chr7 45954422 45960739 WES colorectal IGH@ 3492 immunoglobulin heavy locus 14q32.33 - 5477 - - - - known 1 0 -1 Vertebrates 0 0 -1 32 - 0 0 CGC leukemia,lymphoma,myeloma,non-hodgkin lymphoma IGK@ 50802 immunoglobulin kappa locus 2p12 - 5715 - - - - known 1 0 -1 Vertebrates 18 0 -1 23 - 0 0 CGC lymphoma,non-hodgkin lymphoma IGL@ 3535 immunoglobulin lambda locus 22q11.2 - 5853 - - - - known 1 0 -1 Eukaryotes 0 0 -1 90 - 0 0 CGC lymphoma IGSF10 285313 immunoglobulin superfamily, member 10 3q25.1 13732 26384 - "NP_001171616;NP_001171617;NP_849144" "NM_001178145;NM_001178146;NM_178822" - candidate 0 0 0 Eukaryotes 2 2 Cellular metabolism,Cellular processes,Development -1 chr3 151154480 151176497 WES,WGS pancreas,liver IGSF22 283284 immunoglobulin superfamily, member 22 11p15.1 8229 26750 - NP_775859 NM_173588 ENSP00000421191 candidate 0 0 0 Last Universal Common Ancestor 4 0 -1 -1 chr11 18726018 18745783 WES colorectal IKZF1 10320 IKAROS family zinc finger 1 (Ikaros) 7p13-p11.1 4318 13176 603023 "NP_006051;NP_001207705;NP_001207704;NP_001207703;NP_001207698;NP_001207695;NP_001207702;NP_001207700;NP_001207699;NP_001207701;NP_001207697;NP_001207696;NP_001207694" "NM_006060;NM_001220776;NM_001220775;NM_001220774;NM_001220769;NM_001220766;NM_001220773;NM_001220771;NM_001220770;NM_001220772;NM_001220768;NM_001220767;NM_001220765" "ENSP00000342750;ENSP00000349928;ENSP00000342485;ENSP00000331614" known 1 1 0 Eukaryotes 7 1 Cellular metabolism,DNA/RNA metabolism and transcription,Development,Regulation of intracellular processes and metabolism,Regulation of transcription 78 chr7 50358658 50468322 CGC leukemia,lymphoma IL10 3586 interleukin 10 1q31-q32 495 5962 124092 NP_000563 NM_000572 ENSP00000412237 candidate 0 0 0 Vertebrates 4 1 Cell cycle,Cell motility and interactions,Cell response to stimuli,Cellular metabolism,Cellular processes,DNA/RNA metabolism and transcription,Development,Immune system response,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction 17 chr1 206941984 206945780 WGS lymphoma IL18R1 8809 interleukin 18 receptor 1 2q12 5138 5988 604494 NP_003846 NM_003855 ENSP00000233957 candidate 0 0 0 Eukaryotes 5 3 Immune system response,Signal transduction 7 chr2 102979121 103013343 WGS prostate IL1A 3552 interleukin 1, alpha 2q14 988 5991 147760 NP_000566 NM_000575 - candidate 0 0 0 Mammals 12 2 Cell cycle,Cell response to stimuli,Development,Immune system response,Regulation of intracellular processes and metabolism 53 chr2 113532647 113541347 HTMS breast,lung,ovarian,pancreas,prostate IL1B 3553 interleukin 1, beta 2q14 985 5992 147720 NP_000567 NM_000576 ENSP00000263341 candidate 0 0 0 Vertebrates 16 1 Cell cycle,Cell motility and interactions,Cell response to stimuli,Cellular metabolism,Cellular processes,DNA/RNA metabolism and transcription,Development,Immune system response,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction 67 chr2 113587941 113593806 HTMS,WES breast,lung,ovarian,pancreas,prostate IL1RL1 9173 interleukin 1 receptor-like 1 2q12 3123 5998 601203 "NP_003847;NP_057316" "NM_173459;NM_003856;NM_016232" "ENSP00000386618;ENSP00000233954" candidate 0 0 0 Eukaryotes 26 1 Immune system response,Signal transduction 33 chr2 102954725 102968378 WGS melanoma IL2 3558 interleukin 2 4q26-q27 979 6001 147680 NP_000577 NM_000586 - known 1 0 0 Mammals 2 1 Cell cycle,Development,Immune system response,Regulation of intracellular processes and metabolism 10 chr4 123372910 123377595 CGC lymphoma IL20RB 53833 interleukin 20 receptor beta 3q22.3 14594 6004 605621 NP_653318 NM_144717 ENSP00000328133 candidate 0 0 0 Vertebrates 14 0 -1 -1 chr3 136676956 136729062 WGS chronic lymphocytic leukemia IL21R 50615 interleukin 21 receptor 16p11 5649 6006 605383 "NP_068570;NP_851565;NP_851564" "NM_021798;NM_181079;NM_181078" - known 1 0 0 Vertebrates 5 5 Immune system response 12 chr16 27414492 27460601 CGC non-hodgkin lymphoma IL2RG 3561 interleukin 2 receptor, gamma Xq13.1 2391 6010 308380 NP_000197 NM_000206 ENSP00000363318 candidate 0 0 0 Vertebrates 29 0 Signal transduction 80 chrX 70327589 70331389 WES pancreas IL6ST 3572 interleukin 6 signal transducer (gp130, oncostatin M receptor) 5q11.2 2824 6021 600694 "NP_001177910;NP_002175;NP_786943" "NM_001190981;NM_002184;NM_175767" "ENSP00000370698;ENSP00000370687" known 1 0 0 Eukaryotes 43 4 Signal transduction 100 chr5 55236913 55272106 CGC liver IL7R 3575 interleukin 7 receptor 5p13 893 6024 146661 NP_002176 NM_002185 ENSP00000306157 known 1 0 0 Vertebrates 1 1 DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction 69 chr5 35857080 35876585 CGC leukemia IMP4 92856 IMP4, U3 small nucleolar ribonucleoprotein, homolog (yeast) 2q21.1 10002 30856 612981 NP_219484 NM_033416 ENSP00000386411 candidate 0 0 0 Last Universal Common Ancestor 34 1 DNA/RNA metabolism and transcription,Regulation of transcription 71 chr2 131100659 131104038 WES glioblastoma IMPG2 50939 interphotoreceptor matrix proteoglycan 2 3q12.2-q12.3 6135 18362 607056 NP_057331 NM_016247 - candidate 0 0 0 Metazoans 0 0 -1 20 chr3 100947640 101039216 WGS acute myeloid leukemia INHBA 3624 inhibin, beta A 7p15-p13 929 6066 147290 NP_002183 NM_002192 - candidate 0 0 0 Metazoans 17 1 Cell cycle,Cellular metabolism,Cellular processes,DNA/RNA metabolism and transcription,Development,Immune system response,Multicellular activities,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction 21 chr7 41729251 41739972 HTMS lung INHBE 83729 inhibin, beta E 12q13.3 11047 24029 612031 NP_113667 NM_031479 ENSP00000266646 candidate 0 0 0 Mammals 30 2 -1 11 chr12 57849320 57850628 WES breast IRAK2 3656 interleukin-1 receptor-associated kinase 2 3p25.3 4491 6113 603304 NP_001561 NM_001570 ENSP00000256458 candidate 0 0 0 Last Universal Common Ancestor 26 2 Cellular metabolism,Cellular processes,Immune system response,Signal transduction -1 chr3 10206639 10283909 WGS breast IRAK4 51135 interleukin-1 receptor-associated kinase 4 12q12 6051 17967 606883 "NP_001107654;NP_001138728;NP_057207;NP_001138730;NP_001138729" "NM_001114182;NM_001145256;NM_016123;NM_001145258;NM_001145257" ENSP00000390327 candidate 0 0 0 Last Universal Common Ancestor 30 2 Cellular metabolism,Cellular processes,Signal transduction 40 chr12 44161915 44180363 HTMS breast,lung,ovarian,pancreas,prostate IRF2 3660 interferon regulatory factor 2 4q34.1-q35.1 962 6117 147576 NP_002190 NM_002199 ENSP00000377218 candidate 0 0 0 Metazoans 13 1 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription 66 chr4 185309915 185350218 WES liver IRF4 3662 interferon regulatory factor 4 6p25-p23 3543 6119 601900 "NP_001182215;NP_002451" "NM_001195286;NR_036585;NM_002460;NR_046000" ENSP00000370343 known 1 0 0 Metazoans 31 1 Cellular metabolism,DNA/RNA metabolism and transcription,Development,Immune system response,Regulation of intracellular processes and metabolism,Regulation of transcription 68 chr6 393153 407595 CGC,WES myeloma,non-hodgkin lymphoma IRF6 3664 interferon regulatory factor 6 1q32.3-q41 6227 6121 607199 "NP_001193625;NP_006138" "NM_001206696;NM_006147" ENSP00000355988 candidate 0 0 0 Metazoans 3 1 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription 82 chr1 209961768 209974758 WES head and neck squamous cell carcinoma IRF8 3394 interferon regulatory factor 8 16q24.1 3336 5358 601565 NP_002154 NM_002163 ENSP00000268638 candidate 0 0 0 Vertebrates 30 0 Cellular metabolism,DNA/RNA metabolism and transcription,Development,Regulation of intracellular processes and metabolism,Regulation of transcription 86 chr16 85936622 85954885 WES non-hodgkin lymphoma IRS1 3667 insulin receptor substrate 1 2q36 943 6125 147545 NP_005535 NM_005544 - candidate 0 0 0 Metazoans 89 7 Cell response to stimuli,Regulation of intracellular processes and metabolism,Signal transduction 59 chr2 227659729 227663454 HTMS sarcoma IRS4 8471 insulin receptor substrate 4 Xq22.3 4620 6128 603510 NP_003595 NM_003604 ENSP00000361202 candidate 0 0 0 Metazoans 143 0 Signal transduction 41 chrX 107975804 107979574 WES colorectal IRX6 79190 iroquois homeobox 6 16q12.2 12091 14675 606196 NP_077311 NM_024335 - candidate 0 0 0 Eukaryotes 0 0 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription -1 chr16 55359004 55363222 WES glioblastoma IST1 9798 increased sodium tolerance 1 homolog (yeast) 16q22.2 13784 28977 - NP_055576 NM_014761 - known 0 0 1 Eukaryotes 17 2 -1 101 chr16 71949544 71961699 CGC,Amplified ITCH 83737 itchy E3 ubiquitin protein ligase homolog (mouse) 20q11.22 - 13890 606409 NP_113671 NM_031483 ENSP00000363998 candidate 0 0 0 Eukaryotes 129 1 Cell cycle,Cell motility and interactions,Cellular metabolism,Cellular processes,Immune system response,Other,Regulation of intracellular processes and metabolism 66 chr20 32981618 33095596 HTMS breast,lung,ovarian,pancreas,prostate ITGAE 3682 "integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide)" 17p13 5249 6147 604682 NP_002199 NM_002208 ENSP00000263087 candidate 0 0 0 Eukaryotes 5 0 Signal transduction 103 chr17 3618144 3680952 WES colorectal ITGB1BP3 27231 integrin beta 1 binding protein 3 19p13.3 16371 17871 608705 NP_733778 "NM_014446;NM_170678" ENSP00000168977 candidate 0 0 0 Last Universal Common Ancestor 9 3 Cellular metabolism,DNA/RNA metabolism and transcription 43 chr19 3936574 3942268 WES melanoma ITIH3 3699 inter-alpha-trypsin inhibitor heavy chain 3 3p21.1 891 6168 146650 NP_002208 NM_002217 ENSP00000415769 candidate 0 0 0 Last Universal Common Ancestor 2 0 Cellular metabolism 30 chr3 52828820 52842694 WGS liver ITK 3702 IL2-inducible T-cell kinase 5q31-q32 1746 6171 186973 NP_005537 NM_005546 ENSP00000398655 known 1 0 0 Last Universal Common Ancestor 37 0 Cell response to stimuli,Cellular metabolism,Cellular processes,Signal transduction 81 chr5 156607989 156679685 CGC,HTMS lymphoma,breast,lung,ovarian,pancreas,prostate ITLN1 55600 intelectin 1 (galactofuranose binding) 1q21.3 17165 18259 609873 NP_060095 NM_017625 ENSP00000323587 candidate 0 0 1 Metazoans 1 0 Cell response to stimuli,Cellular metabolism,Cellular processes,Regulation of intracellular processes and metabolism,Signal transduction -1 chr1 160846457 160854667 WES melanoma ITPR3 3710 inositol 1,4,5-trisphosphate receptor, type 3 6p21 926 6182 147267 NP_002215 NM_002224 ENSP00000363435 candidate 0 0 0 Eukaryotes 22 0 Cellular processes,Signal transduction 68 chr6 33589380 33663554 HTMS breast,lung,ovarian,pancreas,prostate JAK1 3716 Janus kinase 1 1p32.3-p31.3 992 6190 147795 NP_002218 NM_002227 ENSP00000343204 known 1 0 0 Last Universal Common Ancestor 98 4 Cellular metabolism,Cellular processes,Signal transduction 107 chr1 65300248 65349161 CGC,WGS leukemia,prostate JAK2 3717 Janus kinase 2 9p24 993 6192 147796 NP_004963 NM_004972 ENSP00000371067 known 1 0 0 Last Universal Common Ancestor 128 4 Cell cycle,Cellular metabolism,Cellular processes,Development,Regulation of intracellular processes and metabolism,Signal transduction 29 chr9 5021988 5126788 CGC,WGS leukemia,myeloma,breast,liver JAK3 3718 Janus kinase 3 19p13.1 2547 6193 600173 NP_000206 NM_000215 ENSP00000391676 known 1 0 0 Last Universal Common Ancestor 47 1 Cellular metabolism,Cellular processes 66 chr19 17937555 17955226 CGC leukemia JAKMIP3 282973 Janus kinase and microtubule interacting protein 3 10q26.3 12574 23523 611198 NP_001098991 "NM_001104947;NM_194303;NM_001105521" ENSP00000298622 candidate 0 0 0 Metazoans 22 1 -1 -1 chr10 133918313 133978239 WGS glioblastoma JARID2 3720 jumonji, AT rich interactive domain 2 6p24-p23 3355 6196 601594 NP_004964 NM_004973 ENSP00000341280 candidate 0 0 0 Eukaryotes 10 11 Cellular metabolism,DNA/RNA metabolism and transcription,Development,Regulation of intracellular processes and metabolism,Regulation of transcription 108 chr6 15246771 15520479 WGS melanoma JAZF1 221895 JAZF zinc finger 1 7p15.2-p15.1 9373 28917 606246 NP_778231 NM_175061 ENSP00000283928 known 1 0 0 Opisthokonts 2 2 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription -1 chr7 27872422 28220196 CGC endometrium JKAMP 51528 JNK1/MAPK8-associated membrane protein 14q23.1 12623 20184 611176 "NP_001092095;NP_057559" "NM_001098625;NM_016475" - candidate 0 0 0 Metazoans 7 0 -1 -1 chr14 59953430 59970787 WES breast JSRP1 126306 junctional sarcoplasmic reticulum protein 1 19p13.3 8724 24963 608743 NP_653217 NM_144616 ENSP00000300961 candidate 0 0 0 Mammals 0 0 -1 -1 chr19 2252331 2255313 WGS lymphoma JUN 3725 jun proto-oncogene 1p32-p31 1302 6204 165160 NP_002219 NM_002228 ENSP00000360266 known 1 0 0 Opisthokonts 56 7 Cellular metabolism,Cellular processes,DNA/RNA metabolism and transcription,Development,Regulation of intracellular processes and metabolism,Regulation of transcription 106 chr1 59247750 59248742 CGC,Amplified sarcoma KALRN 8997 kalirin, RhoGEF kinase 3q21.2 12169 4814 604605 "NP_003938;NP_008995;NP_001019831" "NM_003947;NM_007064;NM_001024660;NR_028136" "ENSP00000353109;ENSP00000240874;ENSP00000291478" candidate 0 0 0 Eukaryotes 25 1 Cellular metabolism,Cellular processes,Development,Signal transduction 63 chr3 123813685 124438314 WES colorectal KAT6A 7994 K(lysine) acetyltransferase 6A 8p11 3244 13013 601408 "NP_006757;NP_001092883;NP_001092882" "NM_006766;NM_001099413;NM_001099412" "ENSP00000380136;ENSP00000385888;ENSP00000265713" known 1 0 0 Eukaryotes 31 2 Cellular metabolism,Cellular processes,DNA/RNA metabolism and transcription,Development,Regulation of intracellular processes and metabolism,Regulation of transcription 106 chr8 41789726 41906495 CGC leukemia KAT6B 23522 K(lysine) acetyltransferase 6B 10q22.2 7065 17582 605880 NP_036462 NM_012330 "ENSP00000361796;ENSP00000361809;ENSP00000287239" known 1 0 0 Eukaryotes 1 3 Cellular metabolism,Cellular processes,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription 100 chr10 76602616 76790801 CGC leukemia KAZN 23254 kazrin, periplakin interacting protein 1p36.21 11122 29173 - "NP_056024;NP_001018001;NP_963922;NP_001017999;NP_001018000" "NM_015209;NM_001018001;NM_201628;NM_001017999;NM_001018000" "ENSP00000354727;ENSP00000383602;ENSP00000391728;ENSP00000365198" candidate 0 0 0 Metazoans 7 0 Development 74 chr1 14925494 15441128 WGS liver KBTBD11 9920 kelch repeat and BTB (POZ) domain containing 11 8p23.3 17195 29104 - NP_055682 NM_014867 ENSP00000321544 candidate 0 0 0 Eukaryotes 1 3 -1 49 chr8 1949359 1951227 WES pancreas KCNA6 3742 potassium voltage-gated channel, shaker-related subfamily, member 6 12p13 8884 6225 176257 NP_002226 NM_002235 ENSP00000408321 candidate 0 0 1 Last Universal Common Ancestor 1 0 Cellular processes 44 chr12 4919208 4920794 WES head and neck squamous cell carcinoma KCNAB1 7881 potassium voltage-gated channel, shaker-related subfamily, beta member 1 3q26.1 3089 6228 601141 "NP_751891;NP_751892;NP_003462" "NM_172159;NM_172160;NM_003471" "ENSP00000418956;ENSP00000305858;ENSP00000419952" candidate 0 0 0 Last Universal Common Ancestor 112 0 Cellular processes 59 chr3 155838401 156254533 WES chronic lymphocytic leukemia KCNC2 3747 potassium voltage-gated channel, Shaw-related subfamily, member 2 12q14.1 8883 6234 176256 "NP_631875;NP_631874;NP_715624" "NM_139137;NM_139136;NM_153748" "ENSP00000340121;ENSP00000298972;ENSP00000449253;ENSP00000319877" candidate 0 0 0 Last Universal Common Ancestor 1 0 Cellular processes 3 chr12 75436888 75601763 WGS lung,melanoma KCNG4 93107 potassium voltage-gated channel, subfamily G, member 4 16q24.1 16253 19697 607603 NP_758857 "NM_172347;NM_133490" - candidate 0 0 0 Last Universal Common Ancestor 3 0 Cellular processes -1 chr16 84255826 84271091 WGS breast KCNJ12 3768 potassium inwardly-rectifying channel, subfamily J, member 12 17p11.2 9083 6258 602323 NP_066292 NM_021012 ENSP00000463778 candidate 0 0 -1 Last Universal Common Ancestor 0 0 Cellular processes,Multicellular activities 16 - 0 0 WGS lymphoma KCNN3 3782 potassium intermediate/small conductance calcium-activated channel, subfamily N, member 3 1q21.3 4283 6292 602983 "NP_001191016;NP_002240;NP_740752" "NM_001204087;NM_002249;NM_170782" - candidate 0 0 0 Eukaryotes 3 0 Cellular processes,Development,Multicellular activities 0 chr1 154680455 154842440 WGS lung KCNQ3 3786 potassium voltage-gated channel, KQT-like subfamily, member 3 8q24 9077 6297 602232 "NP_001191753;NP_004510" "NM_001204824;NM_004519" - candidate 0 0 0 Last Universal Common Ancestor 7 0 Cellular processes,Multicellular activities 31 chr8 133141512 133492779 WGS prostate KCNQ5 56479 potassium voltage-gated channel, KQT-like subfamily, member 5 6q14 16241 6299 607357 "NP_001153605;NP_001153604;NP_062816;NP_001153606;NP_001153602" "NM_001160133;NM_001160132;NM_019842;NM_001160134;NM_001160130" "ENSP00000345055;ENSP00000359425" candidate 0 0 0 Last Universal Common Ancestor 16 0 Cellular processes,Multicellular activities -1 chr6 73331918 73905134 WES colorectal KCNT1 57582 potassium channel, subfamily T, member 1 9q34.3 - 18865 608167 NP_065873 NM_020822 ENSP00000360822 candidate 0 0 0 Last Universal Common Ancestor 0 0 Cellular processes -1 chr9 138594105 138684004 WGS prostate KCTD8 386617 potassium channel tetramerisation domain containing 8 4p13 13771 22394 - NP_938167 NM_198353 ENSP00000353129 candidate 0 0 0 Eukaryotes 1 0 Cellular processes -1 chr4 44176810 44450540 WES head and neck squamous cell carcinoma KDM2B 84678 lysine (K)-specific demethylase 2B 12q24.31 12362 13610 609078 "NP_001005366;NP_115979" "NM_001005366;NM_032590" "ENSP00000366269;ENSP00000366271" candidate 0 0 0 Eukaryotes 18 2 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription -1 chr12 121868094 122018816 WES lymphoma KDM3A 55818 lysine (K)-specific demethylase 3A 2p11.2 11054 20815 611512 "NP_060903;NP_001140160" "NM_018433;NM_001146688" "ENSP00000386516;ENSP00000323659" candidate 0 0 0 Eukaryotes 11 0 Cellular metabolism,Cellular processes,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction 98 chr2 86669171 86719239 WGS chronic lymphocytic leukemia KDM5A 5927 lysine (K)-specific demethylase 5A 12p11 8915 9886 180202 NP_001036068 "NM_005056;NM_001042603" ENSP00000382688 known 1 0 0 Eukaryotes 2 1 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription 81 chr12 394625 498257 CGC leukemia KDM5B 10765 lysine (K)-specific demethylase 5B 1q32.1 9251 18039 605393 NP_006609 NM_006618 ENSP00000356234 candidate 0 0 0 Eukaryotes 2 2 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription 96 chr1 202698167 202777433 WES breast KDM5C 8242 lysine (K)-specific demethylase 5C Xp11.22-p11.21 2442 11114 314690 "NP_004178;NP_001140174" "NM_004187;NM_001146702" "ENSP00000445176;ENSP00000364550" known 0 1 1 Eukaryotes 19 0 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription 86 chrX 53222152 53254071 CGC,HTMS,WES kidney KDM6A 7403 lysine (K)-specific demethylase 6A Xp11.2 2131 12637 300128 NP_066963 NM_021140 ENSP00000367203 known 0 1 1 Last Universal Common Ancestor 31 0 DNA/RNA metabolism and transcription 69 chrX 44732798 44969494 CGC,HTMS,WES,WGS kidney,myeloma,oesophageal,medulloblastoma,prostate KDR 3791 kinase insert domain receptor (a type III receptor tyrosine kinase) 4q11-q12 1867 6307 191306 NP_002244 NM_002253 ENSP00000263923 known 1 0 0 Last Universal Common Ancestor 64 3 Cellular metabolism,Cellular processes,Development,Signal transduction 49 chr4 55946111 55991460 CGC,HTMS lung,sarcoma,breast,ovarian,pancreas,prostate KDSR 2531 3-ketodihydrosphingosine reductase 18q21.3 640 4021 136440 NP_002026 NM_002035 ENSP00000385083 known 1 0 0 Last Universal Common Ancestor 1 6 -1 89 chr18 60999018 61034351 CGC non-hodgkin lymphoma KEAP1 9817 kelch-like ECH-associated protein 1 19p13.2 12079 23177 606016 "NP_036421;NP_987096" "NM_012289;NM_203500" "ENSP00000377245;ENSP00000171111" candidate 0 0 0 Last Universal Common Ancestor 90 4 Cellular metabolism,DNA/RNA metabolism and transcription,Development,Regulation of intracellular processes and metabolism,Regulation of transcription 47 chr19 10597331 10610709 HTMS,WES breast,lung,ovarian,pancreas,prostate KHDRBS2 202559 KH domain containing, RNA binding, signal transduction associated 2 6q11.1 13775 18114 610487 NP_689901 NM_152688 ENSP00000281156 candidate 0 0 0 Eukaryotes 57 2 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription 24 chr6 62390871 62995853 WES,WGS melanoma,liver KHNYN 23351 KH and NYN domain containing 14q12 11076 20166 - NP_056114 NM_015299 ENSP00000251343 candidate 0 0 0 Eukaryotes 6 2 -1 97 chr14 24899937 24906488 WGS liver KHSRP 8570 KH-type splicing regulatory protein 19p13.3 10350 6316 603445 NP_003676 NM_003685 ENSP00000381216 candidate 0 0 1 Eukaryotes 15 4 Cellular metabolism,Cellular processes,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription 103 chr19 6415149 6424712 WES lung KIAA0182 23199 KIAA0182 16q24.1 11066 28979 - "NP_001127945;NP_055430" "NM_001134473;NM_014615" "ENSP00000376934;ENSP00000253458" candidate 0 0 0 Metazoans 12 1 -1 101 chr16 85667519 85706142 WES colorectal KIAA0556 23247 KIAA0556 16p12.1 13806 29068 - NP_056017 NM_015202 ENSP00000261588 candidate 0 0 0 Eukaryotes 1 0 -1 75 chr16 27585221 27789947 WES colorectal KIAA0664 23277 KIAA0664 17p13.3 10014 29094 - NP_056044 NM_015229 ENSP00000388872 candidate 0 0 0 Last Universal Common Ancestor 331 4 Cellular metabolism,Regulation of transcription 97 chr17 2593891 2607844 WES breast KIAA0947 23379 KIAA0947 5p15.32 - 29154 - NP_056140 NM_015325 ENSP00000296564 candidate 0 0 0 Metazoans 8 1 -1 89 chr5 5423029 5489440 WGS prostate KIAA1024 23251 KIAA1024 15q25.1 17206 29172 - NP_056021 NM_015206 ENSP00000307461 candidate 0 0 0 Vertebrates 0 1 -1 8 chr15 79748490 79760723 WES pancreas KIAA1161 57462 KIAA1161 9p13.3 17208 19918 - NP_065753 NM_020702 - candidate 0 0 0 Last Universal Common Ancestor 1 1 -1 -1 chr9 34370800 34372941 WGS glioblastoma KIAA1324 57535 KIAA1324 1p13.3 13850 29618 611298 NP_065826 NM_020775 - candidate 0 0 0 Eukaryotes 0 1 -1 66 chr1 109656806 109745631 WGS chronic lymphocytic leukemia KIAA1468 57614 KIAA1468 18q21.33 13866 29289 - NP_065905 NM_020854 ENSP00000381198 candidate 0 0 0 Eukaryotes 1 0 -1 -1 chr18 59854739 59972764 WGS breast KIAA1549 57670 KIAA1549 7q34 - 22219 613344 "NP_001158137;NP_065961" "NM_001164665;NM_020910" ENSP00000406661 known 1 0 0 Metazoans 18 3 -1 25 chr7 138522654 138666015 CGC pilocytic astrocytoma KIAA1751 85452 KIAA1751 1p36.33 - 29368 - NP_001073953 NM_001080484 ENSP00000270720 candidate 0 0 0 Metazoans 0 0 -1 57 chr1 1887020 1922395 WES,WGS pancreas,glioblastoma KIAA1804 84451 mixed lineage kinase 4 1q42 10087 - - NP_115811 NM_032435 ENSP00000355583 candidate 0 0 0 Last Universal Common Ancestor 10 6 Cellular metabolism,Cellular processes,Regulation of intracellular processes and metabolism,Signal transduction -1 chr1 233463775 233518454 WES colorectal (non-hypermutated),glioblastoma KIAA2022 340533 KIAA2022 Xq13.3 15957 29433 300524 NP_001008537 NM_001008537 ENSP00000055682 candidate 0 0 0 Eukaryotes 2 0 -1 -1 chrX 73959243 73965485 WES colorectal KIF14 9928 kinesin family member 14 1q32.1 6605 19181 611279 NP_055690 NM_014875 ENSP00000356319 candidate 0 0 0 Eukaryotes 2 6 Cellular processes 40 chr1 200522519 200587851 WES breast KIF1A 547 kinesin family member 1A 2q37.3 3156 888 601255 "NP_004312;NP_001230937" "NM_004321;NM_001244008" "ENSP00000438388;ENSP00000322791" candidate 0 0 0 Eukaryotes 1 0 Cellular processes 38 chr2 241656784 241737169 WGS lung KIF1B 23095 kinesin family member 1B 1p36.2 5818 16636 605995 "NP_055889;NP_904325" "NM_015074;NM_183416" "ENSP00000366290;ENSP00000366297" candidate 0 0 0 Eukaryotes 21 10 Cellular processes,Multicellular activities 63 chr1 10292387 10436642 WES lymphoma KIF1C 10749 kinesin family member 1C 17p13.2 4342 6317 603060 NP_006603 NM_006612 ENSP00000320821 candidate 0 0 0 Eukaryotes 17 1 Cellular processes 15 chr17 4903542 4927443 WGS breast KIF21A 55605 kinesin family member 21A 12q12 10506 19349 608283 "NP_001166936;NP_060111;NP_001166934;NP_001166935" "NM_001173465;NM_017641;NM_001173463;NM_001173464" "ENSP00000379029;ENSP00000354851" candidate 0 0 0 Last Universal Common Ancestor 5 1 Cellular processes -1 chr12 39688229 39836772 WES,WGS lung KIF27 55582 kinesin family member 27 9q21.32 11179 18632 611253 NP_060046 NM_017576 ENSP00000297814 candidate 0 0 0 Eukaryotes 6 1 Cellular processes -1 chr9 86451919 86530506 HTMS breast,lung,ovarian,pancreas,prostate KIF5B 3799 kinesin family member 5B 10p11.22 7214 6324 602809 NP_004512 NM_004521 ENSP00000307078 known 1 0 0 Eukaryotes 29 12 Cellular processes 109 chr10 32304460 32344901 CGC lung KIR3DL1 3811 killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 1 19q13.4 10034 6338 604946 "XP_003403454;NP_037421" "XM_003403406;NM_013289" ENSP00000375608 candidate 0 0 5 Mammals 3 1 -1 33 chr19 55236002 55341727 WGS chronic lymphocytic leukemia KIT 3815 v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog 4q11-q12 1287 6342 164920 "NP_000213;NP_001087241" "NM_000222;NM_001093772" ENSP00000288135 known 1 0 0 Last Universal Common Ancestor 73 5 Cell cycle,Cellular metabolism,Cellular processes,Development,Multicellular activities,Regulation of intracellular processes and metabolism,Signal transduction 71 chr4 55524182 55604720 CGC,HTMS,Amplified gastric,leukemia,mastocytosis,melanoma,testis,sarcoma KLF15 28999 Kruppel-like factor 15 3q21.3 7568 14536 606465 NP_054798 NM_014079 ENSP00000296233 candidate 0 0 0 Last Universal Common Ancestor 3 0 Cellular metabolism,Cellular processes,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription 54 chr3 126062573 126071765 WGS lung KLF2 10365 Kruppel-like factor 2 (lung) 19p13.11 3602 6347 602016 NP_057354 NM_016270 ENSP00000248071 candidate 0 0 0 Last Universal Common Ancestor 28 3 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription 102 chr19 16435735 16437839 WES lymphoma KLF6 1316 Kruppel-like factor 6 10p15 3632 2235 602053 "NP_001153596;NP_001153597;NP_001291" "NM_001008490;NM_001160124;NR_027653;NM_001160125;NM_001300" "ENSP00000445301;ENSP00000419923" known 0 1 0 Last Universal Common Ancestor 20 5 Cell cycle,Cellular metabolism,DNA/RNA metabolism and transcription,Development,Immune system response,Regulation of intracellular processes and metabolism,Regulation of transcription 86 chr10 3821734 3827206 CGC glioma,prostate KLHDC4 54758 kelch domain containing 4 16q24.3 11180 25272 - "NP_060036;NP_001171783;NP_001171785" "NM_017566;NM_001184854;NM_001184856" "ENSP00000262530;ENSP00000325717;ENSP00000270583" candidate 0 0 0 Last Universal Common Ancestor 8 2 -1 77 chr16 87741960 87799496 WES pancreas KLHL4 56062 kelch-like 4 (Drosophila) Xq21.3 2283 6355 300348 "NP_061990;NP_476503" "NM_019117;NM_057162" "ENSP00000362211;ENSP00000362206" candidate 0 0 0 Eukaryotes 10 1 -1 37 chrX 86772897 86924391 WGS breast KLHL6 89857 kelch-like 6 (Drosophila) 3q27.3 10035 18653 614214 NP_569713 NM_130446 ENSP00000341342 candidate 0 0 0 Last Universal Common Ancestor 2 0 -1 -1 chr3 183209718 183273441 WES,WGS lymphoma,non-hodgkin lymphoma,chronic lymphocytic leukemia KLK2 3817 kallikrein-related peptidase 2 19q13.41 1006 6363 147960 "NP_001243009;NP_005542;NP_001002231" "NR_045762;NM_001256080;NM_005551;NM_001002232;NM_001002231;NR_045763" "ENSP00000350748;ENSP00000313581" known 1 0 1 Last Universal Common Ancestor 15 0 Cellular metabolism 28 chr19 51376730 51381812 CGC prostate KNDC1 85442 kinase non-catalytic C-lobe domain (KIND) containing 1 10q26.3 13931 29374 - NP_689856 NM_152643 ENSP00000304437 candidate 0 0 0 Eukaryotes 2 0 Signal transduction -1 chr10 134973972 135038391 WGS acute myeloid leukemia KPNA5 3841 karyopherin alpha 5 (importin alpha 6) 6q22.1 5179 6398 604545 NP_002260 NM_002269 ENSP00000348704 candidate 0 0 2 Eukaryotes 13 4 Cellular processes 16 chr6 117010482 117053483 WES breast KRAS 3845 v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog 12p12.1 1817 6407 190070 "NP_203524;NP_004976" "NM_033360;NM_004985" ENSP00000308495 known 1 0 2 Last Universal Common Ancestor 40 14 Cell cycle,Cell response to stimuli,Cellular processes,Development,Multicellular activities,Regulation of intracellular processes and metabolism,Signal transduction 106 chr12 25368378 25398318 CGC,HTMS,WES,WGS,Amplified colorectal,leukemia,lung,other,pancreas,thyroid,breast,ovarian,prostate,bladder,cholangiocarcinoma,colorectal (non-hypermutated),myelodysplasia,myeloma KREMEN1 83999 kringle containing transmembrane protein 1 22q12.1 11182 17550 609898 "NP_114434;NP_001034659" "NM_032045;NM_001039570;NM_153379" "ENSP00000383189;ENSP00000331242" candidate 0 0 0 Eukaryotes 2 1 Signal transduction -1 chr22 29469119 29538088 HTMS breast,lung,ovarian,pancreas,prostate KRT31 3881 keratin 31 17q12-q21 3047 6448 601077 NP_002268 NM_002277 ENSP00000251645 candidate 0 0 4 Eukaryotes 33 0 Development 32 chr17 39550271 39553791 WGS chronic lymphocytic leukemia KRT73 319101 keratin 73 12q13.3 16304 28928 608247 NP_778238 NM_175068 ENSP00000307014 candidate 0 0 2 Eukaryotes 9 0 -1 -1 chr12 53001983 53012308 WES colorectal KRT79 338785 keratin 79 12q13.13 11183 28930 611160 NP_787028 NM_175834 ENSP00000328358 candidate 0 0 0 Eukaryotes 22 0 -1 -1 chr12 53215659 53228044 WES acute myeloid leukemia KRTAP12-1 353332 keratin associated protein 12-1 21q22.3 11197 20529 - NP_859014 NM_181686 ENSP00000375475 candidate 0 0 3 Mammals 0 0 -1 -1 chr21 46101751 46102038 WES melanoma KRTAP5-1 387264 keratin associated protein 5-1 11p15.5 13948 23596 148022 NP_001005922 NM_001005922 ENSP00000371606 candidate 0 0 -1 - 30 0 -1 -1 - 0 0 WGS lymphoma KRTAP5-5 439915 keratin associated protein 5-5 11p15.5 - 23601 - NP_001001480 NM_001001480 ENSP00000382584 candidate 0 0 7 - 1 0 -1 -1 chr11 1651071 1651781 WES,WGS lymphoma KSR1 8844 kinase suppressor of ras 1 17q11.1-q11.2 - 6465 601132 NP_055053 NM_014238 - candidate 0 0 0 Last Universal Common Ancestor 18 0 Cellular metabolism,Cellular processes,Signal transduction 37 chr17 25904557 25944455 WGS melanoma KTN1 3895 kinectin 1 (kinesin receptor) 14q22.1 2661 6467 600381 "NP_001072990;NP_004977;NP_001072989;NP_891556" "NM_001079522;NM_004986;NM_001079521;NM_182926" "ENSP00000378725;ENSP00000394992;ENSP00000391964" known 1 0 0 Eukaryotes 25 1 Cellular processes 107 chr14 56078767 56146402 CGC thyroid LAMA1 284217 laminin, alpha 1 18p11.3 1033 6481 150320 NP_005550 NM_005559 ENSP00000374309 candidate 0 0 0 Eukaryotes 24 3 Cell cycle,Cell motility and interactions,Development,Regulation of intracellular processes and metabolism 11 chr18 6942081 7117719 WES breast,colorectal LAMA2 3908 laminin, alpha 2 6q22-q23 1125 6482 156225 "NP_000417;NP_001073291" "NM_000426;NM_001079823" ENSP00000400365 candidate 0 0 0 Last Universal Common Ancestor 9 0 Cell motility and interactions,Development 76 chr6 129204391 129837489 WES cholangiocarcinoma LAMA4 3910 laminin, alpha 4 6q21 2532 6484 600133 "NP_001098678;NP_002281;NP_001098677;NP_001098676;NP_001098679" "NM_001105208;NM_002290;NM_001105207;NM_001105206;NM_001105209" "ENSP00000230538;ENSP00000429488;ENSP00000398226;ENSP00000374114" candidate 0 0 0 Eukaryotes 34 3 Cell motility and interactions,Development 95 chr6 112430643 112575352 WES bladder LASP1 3927 LIM and SH3 protein 1 17q11-q21.3 4229 6513 602920 NP_006139 NM_006148 ENSP00000325240 known 1 0 0 Eukaryotes 22 7 Cellular processes 109 chr17 37026443 37075028 CGC leukemia LCK 3932 lymphocyte-specific protein tyrosine kinase 1p34.3 1080 6524 153390 "NP_005347;NP_001036236" "NM_005356;NM_001042771" "ENSP00000328213;ENSP00000337825" known 1 0 0 Last Universal Common Ancestor 196 1 Cell cycle,Cell response to stimuli,Cellular metabolism,Cellular processes,Development,Immune system response,Regulation of intracellular processes and metabolism,Signal transduction 25 chr1 32739931 32751314 CGC leukemia LCN9 392399 lipocalin 9 9q34.3 13979 17442 612903 NP_001001676 NM_001001676 ENSP00000277526 candidate 0 0 0 Mammals 0 1 -1 -1 chr9 138555168 138557756 WES colorectal LCP1 3936 lymphocyte cytosolic protein 1 (L-plastin) 13q14.3 1082 6528 153430 NP_002289 NM_002298 ENSP00000315757 known 1 0 1 Eukaryotes 9 2 Cellular processes 70 chr13 46701729 46733797 CGC non-hodgkin lymphoma LDB1 8861 LIM domain binding 1 10q24-q25 9144 6532 603451 "NP_001106878;NP_003884" "NM_001113407;NM_003893" "ENSP00000392466;ENSP00000354616" candidate 0 0 0 Eukaryotes 48 0 Cell cycle,Cellular metabolism,DNA/RNA metabolism and transcription,Development,Multicellular activities,Regulation of intracellular processes and metabolism,Regulation of transcription 59 chr10 103867853 103871294 WES medulloblastoma LDLRAD1 388633 low density lipoprotein receptor class A domain containing 1 1p32.3 17372 32069 - NP_001010978 NM_001010978 ENSP00000360411 candidate 0 0 0 Vertebrates 0 0 -1 -1 chr1 54474658 54483103 WES melanoma LEPRE1 64175 leucine proline-enriched proteoglycan (leprecan) 1 1p34.1 11227 19316 610339 "NP_001139761;NP_001230175;NP_071751" "NM_001146289;NM_001243246;NM_022356" "ENSP00000380245;ENSP00000236040;ENSP00000296388" candidate 0 0 0 Eukaryotes 14 0 Cell cycle,Regulation of intracellular processes and metabolism 92 chr1 43212586 43232642 WGS lung LEPREL1 55214 leprecan-like 1 3q28 17270 19317 610341 "NP_060662;NP_001127890" "NM_018192;NM_001134418" "ENSP00000408947;ENSP00000316881" candidate 0 0 0 Eukaryotes 0 0 -1 28 chr3 189675704 189838520 WGS breast LETM1 3954 leucine zipper-EF-hand containing transmembrane protein 1 4p16.3 5101 6556 604407 NP_036450 NM_012318 ENSP00000305653 candidate 0 0 2 Eukaryotes 10 4 Signal transduction 66 chr4 1816154 1850937 WGS melanoma LGR6 59352 leucine-rich repeat containing G protein-coupled receptor 6 1q32.1 5974 19719 606653 "NP_067649;NP_001017403;NP_001017404" "NM_021636;NM_001017403;NM_001017404" "ENSP00000356247;ENSP00000387869;ENSP00000255432" candidate 0 0 0 Last Universal Common Ancestor 1 1 Signal transduction -1 chr1 202163118 202288332 WES colorectal LHFP 10186 lipoma HMGIC fusion partner 13q12 9464 6586 606710 NP_005771 NM_005780 ENSP00000368908 known 1 0 0 Metazoans 2 2 -1 84 chr13 39918076 40175353 CGC lipoma LIFR 3977 leukemia inhibitory factor receptor alpha 5p13-p12 1048 6597 151443 "NP_001121143;NP_002301" "NM_001127671;NM_002310" ENSP00000263409 known 1 0 0 Eukaryotes 16 10 Cell cycle,Regulation of intracellular processes and metabolism,Signal transduction 29 chr5 38481700 38530749 CGC salivary LILRB1 10859 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1 19q13.4 7273 6605 604811 "NP_001075107;NP_006660;NP_001075108;NP_001075106" "NM_001081638;NM_006669;NM_001081639;NM_001081637" "ENSP00000315997;ENSP00000379618;ENSP00000379623;ENSP00000379622" candidate 0 0 3 Vertebrates 79 0 Cell response to stimuli 24 chr19 55085542 55148326 WES head and neck squamous cell carcinoma LINGO1 84894 leucine rich repeat and Ig domain containing 1 15q24.3 14322 21205 609791 NP_116197 NM_032808 ENSP00000347451 candidate 0 0 0 Last Universal Common Ancestor 7 0 -1 -1 chr15 77906389 77908245 WGS lung LITAF 9516 lipopolysaccharide-induced TNF factor 16p13.13 10354 16841 603795 "NP_001129945;NP_004853;NP_001129944" "NM_001136473;NM_004862;NM_001136472;NR_024320" "ENSP00000397958;ENSP00000340118" candidate 0 0 0 Eukaryotes 14 10 Cell cycle,Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction 107 chr16 11643496 11650586 WGS liver LLGL1 3996 lethal giant larvae homolog 1 (Drosophila) 17p11.2 2982 6628 600966 NP_004131 NM_004140 ENSP00000321537 candidate 0 0 0 Eukaryotes 25 4 Cellular processes,Development 38 chr17 18128997 18146132 WGS chronic lymphocytic leukemia LMO1 4004 LIM domain only 1 (rhombotin 1) 11p15 1738 6641 186921 NP_002306 NM_002315 "ENSP00000404538;ENSP00000338207" known 1 0 1 Eukaryotes 0 0 -1 35 chr11 8246166 8252052 CGC leukemia,neuroblastoma LMO2 4005 LIM domain only 2 (rhombotin-like 1) 11p13 1586 6642 180385 "NP_001135787;NP_001135788;NP_005565" "NM_001142315;NM_001142316;NM_005574" "ENSP00000379175;ENSP00000257818" known 1 0 0 Eukaryotes 22 1 -1 94 chr11 33880905 33891136 CGC leukemia LMO7 4008 LIM domain 7 13q22.2 5078 6646 604362 "NP_056667;NP_005349" "NM_015842;NM_005358;NM_015843" "ENSP00000342112;ENSP00000433352" candidate 0 0 0 Eukaryotes 21 3 Cellular metabolism,Cellular processes 21 chr13 76378463 76432146 WES,WGS colorectal,glioblastoma LMX1A 4009 LIM homeobox transcription factor 1, alpha 1q24.1 2623 6653 600298 "NP_001167540;NP_796372" "NM_001174069;NM_001033507;NM_177399;NM_177398" "ENSP00000294816;ENSP00000340226" candidate 0 0 0 Eukaryotes 6 0 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription -1 chr1 165173120 165324796 WES glioblastoma LOC392232 392232 transient receptor potential cation channel, subfamily A, member 1 pseudogene 8q13.3 - - - - NR_033867 - candidate 0 0 -1 - 0 0 -1 -1 - 0 0 WES melanoma LPHN1 22859 latrophilin 1 19p13.2 14305 20973 - "NP_055736;NP_001008701" "NM_014921;NM_001008701" - candidate 0 0 0 Eukaryotes 12 4 Signal transduction 76 chr19 14261688 14294414 WES pancreas LPHN2 23266 latrophilin 2 1p31.1 6116 18582 607018 NP_036434 NM_012302 ENSP00000322270 candidate 0 0 0 Eukaryotes 2 4 Signal transduction 67 chr1 82302670 82456826 WES chronic lymphocytic leukemia LPHN3 23284 latrophilin 3 4q13.1 10055 20974 - NP_056051 NM_015236 ENSP00000439831 candidate 0 0 0 Eukaryotes 17 0 Signal transduction 56 chr4 62363012 62936623 HTMS,WES breast,lung,ovarian,pancreas,prostate,chronic lymphocytic leukemia LPP 4026 LIM domain containing preferred translocation partner in lipoma 3q28 2828 6679 600700 "NP_001161143;NP_001161144;NP_005569" "NM_001167671;NM_001167672;NM_005578" "ENSP00000438891;ENSP00000318089" known 1 0 0 Eukaryotes 19 3 -1 97 chr3 188123909 188592264 CGC leukemia,lipoma LRBA 987 LPS-responsive vesicle trafficking, beach and anchor containing 4q31.3 7344 1742 606453 "NP_001186211;NP_006717" "NM_001199282;NM_006726" "ENSP00000421552;ENSP00000349629" candidate 0 0 0 Eukaryotes 6 0 -1 99 chr4 151186877 151935794 WES breast LRFN5 145581 leucine rich repeat and fibronectin type III domain containing 5 14q21.1 17445 20360 612811 NP_689660 NM_152447 ENSP00000298119 candidate 0 0 0 Eukaryotes 0 0 -1 -1 chr14 42355829 42368163 WES head and neck squamous cell carcinoma,pancreas LRIG3 121227 leucine-rich repeats and immunoglobulin-like domains 3 12q14.1 8317 30991 608870 "NP_001129523;NP_700356" "NM_001136051;NM_153377" "ENSP00000368436;ENSP00000326759" known 1 0 0 Last Universal Common Ancestor 1 3 -1 -1 chr12 59266357 59314016 CGC lung LRP1B 53353 low density lipoprotein receptor-related protein 1B 2q21.2 16383 6693 608766 NP_061027 NM_018557 ENSP00000374135 candidate 0 0 0 Eukaryotes 19 2 Cellular processes 24 chr2 140990758 142888298 HTMS,WES lung,chronic lymphocytic leukemia,gastric,kidney LRP2 4036 low density lipoprotein receptor-related protein 2 2q24-q31 2509 6694 600073 NP_004516 NM_004525 ENSP00000263816 candidate 0 0 0 Eukaryotes 60 0 Cellular metabolism,Cellular processes,Development 34 chr2 169985176 170218909 WES bladder,glioblastoma LRP5 4041 low density lipoprotein receptor-related protein 5 11q13.4 4616 6697 603506 NP_002326 NM_002335 ENSP00000294304 candidate 0 0 0 Last Universal Common Ancestor 2 1 Cell cycle,Cell motility and interactions,Cellular processes,Development,Regulation of intracellular processes and metabolism,Signal transduction 19 chr11 68115314 68216535 WGS lymphoma LRRC30 339291 leucine rich repeat containing 30 18p11.23 - 30219 - NP_001099051 NM_001105581 ENSP00000372959 candidate 0 0 0 Last Universal Common Ancestor 0 0 -1 -1 chr18 7231137 7232039 WGS liver LRRC41 10489 leucine rich repeat containing 41 1p34.1 10102 16917 - NP_006360 NM_006369 ENSP00000343298 candidate 0 0 0 Metazoans 8 1 -1 68 chr1 46744540 46768994 WGS prostate LRRC6 23639 leucine rich repeat containing 6 8q24.22 10286 16725 - NP_036604 NM_012472 ENSP00000250173 candidate 0 0 0 Eukaryotes 32 0 -1 20 chr8 133584557 133673871 WGS lymphoma LRRC7 57554 leucine rich repeat containing 7 1p31.1 9930 18531 614453 NP_065845 NM_020794 ENSP00000035383 candidate 0 0 0 Last Universal Common Ancestor 12 0 -1 -1 chr1 70225888 70587567 WES breast,glioblastoma LRRC8E 80131 leucine rich repeat containing 8 family, member E 19p13.2 8670 26272 612891 NP_079337 NM_025061 ENSP00000306524 candidate 0 0 0 Last Universal Common Ancestor 15 1 -1 29 chr19 7960489 7965795 WGS lung LRRFIP1 9208 leucine rich repeat (in FLII) interacting protein 1 2q37.3 4460 6702 603256 "NP_004726;NP_001131024;NP_001131022;NP_001131025;NP_001131023" "NM_004735;NM_001137552;NM_001137550;NM_001137553;NM_001137551" "ENSP00000289175;ENSP00000244815" candidate 0 0 1 Metazoans 10 5 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription 109 chr2 238601099 238672780 WES,WGS breast,melanoma LRRIQ3 127255 leucine-rich repeats and IQ motif containing 3 1p31.1 14485 28318 - NP_001099129 "NM_001105659;NM_145258" ENSP00000346414 candidate 0 0 0 Eukaryotes 0 0 -1 -1 chr1 74492500 74649368 WES lymphoma LRRK1 79705 leucine-rich repeat kinase 1 15q26.3 14319 18608 610986 NP_078928 NM_024652 ENSP00000373600 candidate 0 0 0 Last Universal Common Ancestor 34 0 Cellular metabolism,Cellular processes,Signal transduction 24 chr15 101464838 101609050 WGS melanoma LRRK2 120892 leucine-rich repeat kinase 2 12q12 - 18618 609007 NP_940980 NM_198578 ENSP00000298910 candidate 0 0 0 Last Universal Common Ancestor 149 2 Cell cycle,Cellular metabolism,Cellular processes,Development,Regulation of intracellular processes and metabolism,Signal transduction -1 chr12 40618934 40761564 WES,WGS kidney,lung LRRN3 54674 leucine rich repeat neuronal 3 7q31.1 14321 17200 - "NP_001093128;NP_060804;NP_001093130" "NM_001099658;NM_018334;NM_001099660" "ENSP00000312001;ENSP00000397312;ENSP00000412417" candidate 0 0 0 Last Universal Common Ancestor 0 2 -1 78 chr7 110762829 110764952 WES pancreas LRRTM1 347730 leucine rich repeat transmembrane neuronal 1 2p12 14323 19408 610867 NP_849161 NM_178839 ENSP00000295057 candidate 0 0 0 Last Universal Common Ancestor 0 3 -1 -1 chr2 80529379 80530944 WES head and neck squamous cell carcinoma LRRTM3 347731 leucine rich repeat transmembrane neuronal 3 10q21.3 14324 19410 610869 NP_821079 NM_178011 - candidate 0 0 0 Last Universal Common Ancestor 0 0 -1 -1 chr10 68686678 68857551 WGS glioblastoma LRRTM4 80059 leucine rich repeat transmembrane neuronal 4 2p12 11288 19411 610870 "NP_079269;NP_001128217" "NM_024993;NM_001134745" ENSP00000386236 candidate 0 0 0 Last Universal Common Ancestor 0 0 -1 22 chr2 77745444 77746991 WES pancreas LSM1 27257 LSM1 homolog, U6 small nuclear RNA associated (S. cerevisiae) 8p11.2 6281 20472 607281 NP_055277 "NR_045493;NM_014462;NR_045492" ENSP00000310596 known 0 0 0 Eukaryotes 18 2 DNA/RNA metabolism and transcription,Regulation of transcription 79 chr8 38021191 38033838 CGC,Amplified LTA4H 4048 leukotriene A4 hydrolase 12q22 1056 6710 151570 NP_000886 NM_000895 "ENSP00000228740;ENSP00000449958;ENSP00000395051" candidate 0 0 0 Last Universal Common Ancestor 16 4 Cellular metabolism,Immune system response 106 chr12 96394770 96429297 WGS acute myeloid leukemia LTBP2 4053 latent transforming growth factor beta binding protein 2 14q24 3650 6715 602091 NP_000419 NM_000428 ENSP00000261978 candidate 0 0 0 Eukaryotes 3 1 Cellular processes,Signal transduction 88 chr14 74967590 75078647 WGS liver LTK 4058 leukocyte receptor tyrosine kinase 15q15.1-q21.1 1052 6721 151520 "NP_002335;NP_996844;NP_001129157" "NM_002344;NM_206961;NM_001135685" "ENSP00000392196;ENSP00000263800;ENSP00000347293" candidate 0 0 0 Last Universal Common Ancestor 11 1 Cellular metabolism,Cellular processes,Signal transduction 24 chr15 41796197 41805907 HTMS lung,sarcoma LUZP2 338645 leucine zipper protein 2 11p14.3 17348 23206 608178 "NP_001009909;NP_001238937;NP_001238939" "NM_001009909;NM_001252008;NM_001252010" ENSP00000432952 candidate 0 0 0 Vertebrates 2 0 -1 31 chr11 24518790 25100201 WES chronic lymphocytic leukemia LYG1 129530 lysozyme G-like 1 2q11.2 14043 27014 - NP_777558 NM_174898 ENSP00000311320 candidate 0 0 0 Mammals 0 0 Cellular metabolism,Cellular processes -1 chr2 99900859 99909110 WGS lymphoma LYL1 4066 lymphoblastic leukemia derived sequence 1 19p13.2 1046 6734 151440 NP_005574 NM_005583 ENSP00000264824 known 1 0 0 Vertebrates 9 1 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription 28 chr19 13210136 13211985 CGC leukemia LZIC 84328 leucine zipper and CTNNBIP1 domain containing 1p36.22 14340 17497 610458 NP_115744 NM_032368 ENSP00000383695 candidate 0 0 0 Eukaryotes 3 3 -1 -1 chr1 9990460 9996677 WGS glioblastoma MACF1 23499 microtubule-actin crosslinking factor 1 1p32-p31 9750 13664 608271 "NP_036222;NP_149033" "NM_012090;NM_033044" ENSP00000439537 candidate 0 0 0 Eukaryotes 13 5 Cell cycle 108 chr1 39549891 39951463 WES pancreas MADD 8567 MAP-kinase activating death domain 11p11.2 4664 6766 603584 "NP_569832;NP_001129415;NP_001129416;NP_569827;NP_003673;NP_569828;NP_569826;NP_569831;NP_569830;NP_569829" "NM_130476;NM_001135943;NM_001135944;NM_130471;NM_003682;NM_130472;NM_130470;NM_130475;NM_130474;NM_130473" "ENSP00000378753;ENSP00000310933;ENSP00000343902;ENSP00000384204;ENSP00000385585;ENSP00000304505;ENSP00000384435;ENSP00000378745;ENSP00000384287" candidate 0 0 0 Last Universal Common Ancestor 13 1 Cell cycle,Cellular metabolism,Cellular processes,Regulation of intracellular processes and metabolism,Signal transduction 95 chr11 47295466 47350698 WGS melanoma MAF 4094 v-maf musculoaponeurotic fibrosarcoma oncogene homolog (avian) 16q22-q23 1518 6776 177075 "NP_001026974;NP_005351" "NM_001031804;NM_005360" "ENSP00000377019;ENSP00000327048" known 1 0 0 Metazoans 21 0 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription 82 chr16 79628360 79633799 CGC myeloma MAFA 389692 v-maf musculoaponeurotic fibrosarcoma oncogene homolog A (avian) 8q24.3 14346 23145 610303 NP_963883 NM_201589 ENSP00000328364 candidate 0 0 0 Metazoans 10 0 Cell response to stimuli,Cellular metabolism,Cellular processes,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction -1 chr8 144511518 144512576 WES head and neck squamous cell carcinoma MAFB 9935 v-maf musculoaponeurotic fibrosarcoma oncogene homolog B (avian) 20q11.2-q13.1 7129 6408 608968 NP_005452 NM_005461 ENSP00000362410 known 1 0 0 Metazoans 10 4 Cellular metabolism,DNA/RNA metabolism and transcription,Development,Multicellular activities,Regulation of intracellular processes and metabolism,Regulation of transcription 55 chr20 39316522 39317490 CGC myeloma MAG 4099 myelin associated glycoprotein 19q13.1 1160 6783 159460 "NP_002352;NP_542167;NP_001186145" "NM_002361;NM_080600;NM_001199216" "ENSP00000440695;ENSP00000376048;ENSP00000355234" candidate 0 0 0 Last Universal Common Ancestor 1 0 -1 36 chr19 35786312 35804354 HTMS breast,lung,ovarian,pancreas,prostate MAGEA6 4105 melanoma antigen family A, 6 Xq28 2168 6804 300176 "NP_787064;NP_005354" "NM_175868;NM_005363" ENSP00000329199 candidate 0 0 6 Eukaryotes 38 2 -1 1 chrX 151869311 151870252 WES pancreas MAGEC1 9947 melanoma antigen family C, 1 Xq26 2201 6812 300223 NP_005453 NM_005462 ENSP00000285879 candidate 0 0 0 Eukaryotes 36 0 -1 32 chrX 140993194 140996616 WES head and neck squamous cell carcinoma MAGEC2 51438 melanoma antigen family C, 2 Xq27 6632 13574 300468 "NP_057333;XP_003403911" "NM_016249;XM_003403863" ENSP00000354660 candidate 0 0 1 Eukaryotes 7 0 -1 41 chrX 141290655 141291773 WES head and neck squamous cell carcinoma MAGEC3 139081 melanoma antigen family C, 3 Xq27.2 6629 23798 300469 "NP_619647;NP_803251" "NM_138702;NM_177456" "ENSP00000298296;ENSP00000440444" candidate 0 0 0 Eukaryotes 0 1 -1 16 chrX 140926102 140985615 WES lymphoma MAGED1 9500 melanoma antigen family D, 1 Xp11.23 2202 6813 300224 "NP_001005333;NP_008917;NP_001005332" "NM_001005333;NM_006986;NM_001005332" "ENSP00000364927;ENSP00000364847;ENSP00000325333" candidate 0 0 0 Eukaryotes 109 0 Cell cycle,Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription 105 chrX 51637401 51645023 WES,WGS myeloma MAGEE1 57692 melanoma antigen family E, 1 Xq13.3 6583 24934 300759 NP_065983 NM_020932 ENSP00000354912 candidate 0 0 0 Last Universal Common Ancestor 8 0 -1 -1 chrX 75648324 75651194 WES,WGS breast,chronic lymphocytic leukemia MALAT1 378938 metastasis associated lung adenocarcinoma transcript 1 (non-protein coding) 11q13.1 - 29665 607924 - NR_002819 - known 1 0 -1 Primates 0 0 -1 -1 - 0 0 CGC kidney MALT1 10892 mucosa associated lymphoid tissue lymphoma translocation gene 1 18q21 6892 6819 604860 "NP_776216;NP_006776" "NM_173844;NM_006785" ENSP00000319279 known 1 0 0 Last Universal Common Ancestor 21 1 Cell cycle,Cell response to stimuli,Cellular metabolism,Cellular processes,Development,Immune system response,Regulation of intracellular processes and metabolism,Signal transduction 50 chr18 56338876 56415071 CGC lymphoma MAMDC4 158056 MAM domain containing 4 9q34.3 12434 24083 - NP_996803 NM_206920 ENSP00000319388 candidate 0 0 0 Eukaryotes 0 0 Cellular processes -1 chr9 139746869 139755052 WES breast MAML2 84441 mastermind-like 2 (Drosophila) 11q21 9608 16259 607537 NP_115803 NM_032427 ENSP00000412394 known 1 0 0 Metazoans 8 1 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction -1 chr11 95712115 96075059 CGC salivary MAP1B 4131 microtubule-associated protein 1B 5q13 1139 6836 157129 NP_005900 "NM_032010;NM_005909" ENSP00000296755 candidate 0 0 0 Last Universal Common Ancestor 23 8 Cell cycle,Cellular metabolism,Cellular processes,Development,Regulation of intracellular processes and metabolism 94 chr5 71403359 71501063 WES colorectal MAP2 4133 microtubule-associated protein 2 2q34-q35 1140 6839 157130 "NP_002365;NP_114035;NP_001034627;NP_114033" "NM_002374;NM_031846;NM_031847;NM_001039538;NM_031845" "ENSP00000353508;ENSP00000376032" candidate 0 0 0 Last Universal Common Ancestor 7 1 Cellular metabolism,Cellular processes,Regulation of intracellular processes and metabolism 43 chr2 210517895 210595118 WES colorectal MAP2K4 6416 mitogen-activated protein kinase kinase 4 17p11.2 3213 6844 601335 NP_003001 NM_003010 ENSP00000262445 known 0 1 1 Last Universal Common Ancestor 47 2 Cellular metabolism,Cellular processes,Signal transduction 83 chr17 11924204 12044574 CGC,WES breast,colorectal,pancreas MAP2K7 5609 mitogen-activated protein kinase kinase 7 19p13.3-p13.2 - 6847 603014 NP_660186 NM_145185 ENSP00000381066 candidate 0 0 0 Last Universal Common Ancestor 10 0 Cellular metabolism,Cellular processes,Signal transduction 59 chr19 7968830 7977313 WES colorectal MAP3K1 4214 mitogen-activated protein kinase kinase kinase 1 5q11.2 - 6848 600982 NP_005912 NM_005921 ENSP00000382423 candidate 0 0 0 Last Universal Common Ancestor 166 2 Cellular metabolism,Cellular processes,Signal transduction 9 chr5 56111401 56189504 HTMS,WES breast,lung,ovarian,pancreas,prostate MAP3K13 9175 mitogen-activated protein kinase kinase kinase 13 3q27 5372 6852 604915 "NP_001229246;NP_004712;NP_001229243" "NM_001242317;NM_004721;NR_038322;NM_001242314" ENSP00000265026 candidate 0 0 0 Last Universal Common Ancestor 7 0 Cellular metabolism,Cellular processes,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction 6 chr3 185146370 185200241 WES breast MAP3K4 4216 mitogen-activated protein kinase kinase kinase 4 6q26 3886 6856 602425 "NP_005913;NP_006715" "NM_005922;NM_006724" "ENSP00000375986;ENSP00000355886" candidate 0 0 0 Last Universal Common Ancestor 27 3 Cellular metabolism,Cellular processes,Regulation of intracellular processes and metabolism,Signal transduction 64 chr6 161412964 161536337 WES endometrium MAP3K5 4217 mitogen-activated protein kinase kinase kinase 5 6q22.33 3904 6857 602448 NP_005914 NM_005923 ENSP00000351908 known 0 0 0 Last Universal Common Ancestor 114 0 Cell cycle,Cellular metabolism,Cellular processes,Development,Regulation of intracellular processes and metabolism,Signal transduction 95 chr6 136878899 137113295 CGC,Amplified MAP3K8 1326 mitogen-activated protein kinase kinase kinase 8 10p11.23 1863 6860 191195 "NP_001231063;NP_005195" "NM_001244134;NM_005204" "ENSP00000364470;ENSP00000263056" candidate 0 0 0 Last Universal Common Ancestor 40 7 Cellular metabolism,Cellular processes 24 chr10 30727868 30749762 WGS breast MAP4K4 9448 mitogen-activated protein kinase kinase kinase kinase 4 2q11.2-q12 5235 6866 604666 "NP_663720;NP_001229488;NP_663719;NP_001229489;NP_004825" "NM_145687;NM_001242559;NM_145686;NM_001242560;NM_004834" - candidate 0 0 0 Last Universal Common Ancestor 42 0 Cellular metabolism,Cellular processes,Signal transduction 84 chr2 102314543 102507708 WGS prostate MAP7 9053 microtubule-associated protein 7 6q23.3 4982 6869 604108 "NP_001185537;NP_001185548;NP_001185540;NP_001185545;NP_001185547;NP_001185538;NP_003971;NP_001185543;NP_001185544;NP_001185546" "NM_001198608;NM_001198619;NM_001198611;NM_001198616;NM_001198618;NM_001198609;NM_003980;NM_001198614;NM_001198615;NM_001198617" ENSP00000346581 candidate 0 0 0 Metazoans 11 7 Cellular processes,Development 68 chr6 136666995 136847102 WES colorectal (hypermutated) MAPK8IP2 23542 mitogen-activated protein kinase 8 interacting protein 2 22q13.33 9674 6883 607755 "NP_057515;NP_036456" "NM_139124;NM_016431;NM_012324" ENSP00000330572 candidate 0 0 0 Metazoans 59 0 Cell cycle,Cellular processes,Development,Regulation of intracellular processes and metabolism,Signal transduction 65 chr22 51039248 51049204 WES colorectal MAPK8IP3 23162 mitogen-activated protein kinase 8 interacting protein 3 16p13.3 12014 6884 605431 "NP_001035529;NP_055948" "NM_001040439;NM_015133" ENSP00000250894 candidate 0 0 0 Metazoans 43 0 Cellular processes,Signal transduction 71 chr16 1756341 1818822 HTMS breast,lung,ovarian,pancreas,prostate MAPKBP1 23005 mitogen-activated protein kinase binding protein 1 15q15.1 17465 29536 - "NP_055809;NP_001122080" "NM_014994;NM_001128608" "ENSP00000393099;ENSP00000426154;ENSP00000397570" candidate 0 0 0 Last Universal Common Ancestor 4 0 -1 27 chr15 42067474 42117631 WES breast MAS1L 116511 MAS1 oncogene-like 6p21 6251 13961 607235 NP_443199 NM_052967 ENSP00000366331 candidate 0 0 0 Mammals 0 3 Signal transduction -1 chr6 29454546 29455679 HTMS breast,lung,ovarian,pancreas,prostate MASP2 10747 mannan-binding lectin serine peptidase 2 1p36.3-p36.2 5484 6902 605102 "NP_006601;NP_631947" "NM_006610;NM_139208" "ENSP00000383690;ENSP00000383691" candidate 0 0 0 Last Universal Common Ancestor 11 0 Cell response to stimuli,Cellular metabolism,Immune system response 80 chr1 11086945 11107178 WGS prostate MBP 4155 myelin basic protein 18q23 1158 6925 159430 "NP_001020271;NP_001020261;NP_001020272;NP_002376;NP_001020263;NP_001020252" "NM_001025100;NM_001025090;NM_001025101;NM_001025098;NM_001025094;NM_002385;NM_001025092;NM_001025081" "ENSP00000372025;ENSP00000380964;ENSP00000380963;ENSP00000380958;ENSP00000348273" candidate 0 0 0 Last Universal Common Ancestor 8 0 Development,Multicellular activities,Regulation of intracellular processes and metabolism 94 chr18 74696731 74817217 WGS chronic lymphocytic leukemia MC3R 4159 melanocortin 3 receptor 20q13.2-q13.3 1115 6931 155540 NP_063941 NM_019888 ENSP00000243911 candidate 0 0 0 Metazoans 5 0 Signal transduction 42 chr20 54823900 54824868 HTMS breast,lung,ovarian,pancreas,prostate MCAM 4162 melanoma cell adhesion molecule 11q23.3 1120 6934 155735 NP_006491 NM_006500 ENSP00000264036 candidate 0 0 0 Eukaryotes 8 8 -1 100 chr11 119181059 119187811 WES acute myeloid leukemia MCFD2 90411 multiple coagulation factor deficiency 2 2p21 9693 18451 607788 "NP_644808;NP_001164979;NP_001164978;NP_001164981;NP_001164982;NP_001164980;NP_001164977" "NM_139279;NM_001171508;NM_001171507;NM_001171510;NM_001171511;NM_001171509;NM_001171506" "ENSP00000386941;ENSP00000387202;ENSP00000394647;ENSP00000317271" candidate 0 0 0 Metazoans 9 2 Cellular metabolism,Cellular processes 90 chr2 47132605 47136310 WGS chronic lymphocytic leukemia MCHR1 2847 melanin-concentrating hormone receptor 1 22q13.2 11874 4479 601751 NP_005288 NM_005297 ENSP00000249016 candidate 0 0 0 Metazoans 0 0 Regulation of intracellular processes and metabolism,Signal transduction 36 chr22 41075450 41077929 WES gastric MCHR2 84539 melanin-concentrating hormone receptor 2 6q16 12088 20867 606111 "NP_115892;NP_001035269" "NM_032503;NM_001040179" "ENSP00000281806;ENSP00000403490" candidate 0 0 0 Vertebrates 1 1 Signal transduction -1 chr6 100368819 100404023 HTMS breast,lung,ovarian,pancreas,prostate MCM3AP 8888 minichromosome maintenance complex component 3 associated protein 21q22.3 4483 6946 603294 NP_003897 NM_003906 ENSP00000291688 candidate 0 0 0 Eukaryotes 35 0 Cellular metabolism,Cellular processes,DNA/RNA metabolism and transcription 86 chr21 47655185 47705200 WES colorectal MCMBP 79892 minichromosome maintenance complex binding protein 10q26.11 7624 25782 610909 "NP_001243308;NP_001243307;NP_079110" "NM_001256379;NM_001256378;NM_024834" ENSP00000353098 candidate 0 0 0 Eukaryotes 19 3 -1 62 chr10 121590989 121632096 WES melanoma MDGA2 161357 MAM domain containing glycosylphosphatidylinositol anchor 2 14q21.3 14352 19835 611128 "NP_001106970;NP_878250" "NM_001113498;NM_182830" "ENSP00000382178;ENSP00000405456" candidate 0 0 0 Last Universal Common Ancestor 0 1 Cell cycle,Development -1 chr14 47311137 48143999 WGS chronic lymphocytic leukemia MDM2 4193 Mdm2 p53 binding protein homolog (mouse) 12q14.3-q15 1272 6973 164785 NP_002383 "NM_032739;NM_006882;NM_001145340;NM_006878;NM_001145337;NM_006880;NM_006881;NM_001145339;NM_006879;NM_002392;NM_001145336" ENSP00000417281 known 1 0 0 Eukaryotes 405 7 Cell cycle,Cellular metabolism,Cellular processes,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription 27 chr12 69202986 69233626 CGC,WES,Amplified colorectal,glioma,other,sarcoma,lung MDM4 4194 Mdm4 p53 binding protein homolog (mouse) 1q32 4082 6974 602704 "NP_001191100;NP_002384;NP_001191101" "NM_001204171;NR_024171;NM_002393;NM_001204172" ENSP00000356150 known 1 0 0 Eukaryotes 75 7 Cell cycle,Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription 8 chr1 204494647 204518807 CGC,Amplified bladder,glioblastoma,retinoblastoma MDP1 145553 magnesium-dependent phosphatase 1 14q12 14695 28781 - "NP_612485;NP_001186751;NP_001186750" "NM_138476;NM_001199822;NM_001199821" "ENSP00000380045;ENSP00000288087" candidate 0 0 0 Last Universal Common Ancestor 2 0 -1 -1 chr14 24683233 24685004 WGS glioblastoma MDS2 259283 myelodysplastic syndrome 2 translocation associated 1p36 - 29633 607305 - NR_027042 - known 1 0 -1 Primates 0 0 -1 -1 - 0 0 CGC myelodysplasia MECOM 2122 MDS1 and EVI1 complex locus 3q26 1310 3498 165215 "NP_005232;NP_001098548;NP_004982;NP_001157471;NP_001098547;NP_001192123;NP_001157472" "NM_005241;NM_001105078;NM_004991;NM_001163999;NM_001105077;NM_001205194;NM_001164000" "ENSP00000264674;ENSP00000419770;ENSP00000376493" known 1 0 0 Last Universal Common Ancestor 21 0 -1 41 chr3 168802700 169099322 CGC leukemia,myelodysplasia MED1 5469 mediator complex subunit 1 17q12 5055 9234 604311 NP_004765 NM_004774 - candidate 0 0 0 Last Universal Common Ancestor 110 2 Cellular metabolism,DNA/RNA metabolism and transcription,Development,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction 69 chr17 37563731 37604158 WES head and neck squamous cell carcinoma MED12 9968 mediator complex subunit 12 Xq13 2176 11957 300188 NP_005111 NM_005120 ENSP00000363193 known 1 0 0 Eukaryotes 63 0 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction 91 chrX 70338605 70362065 CGC,WES uterus,prostate MED12L 116931 mediator complex subunit 12-like 3q25.1 10278 16050 611318 NP_443728 NM_053002 ENSP00000417235 candidate 0 0 0 Eukaryotes 18 1 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription -1 chr3 150804714 151150589 WES lymphoma MED29 55588 mediator complex subunit 29 19q13.2 13748 23074 612914 NP_060062 NM_017592 ENSP00000314343 known 0 0 0 Metazoans 110 0 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription -1 chr19 39882000 39888336 CGC,Amplified MEF2B 100271849 myocyte enhancer factor 2B 19p13.11 - 6995 600661 NP_001139257 NM_001145785 ENSP00000402154 candidate 0 0 0 Eukaryotes 6 0 -1 -1 chr19 19256609 19261544 WES lymphoma,non-hodgkin lymphoma MEF2C 4208 myocyte enhancer factor 2C 5q14 2809 6996 600662 "NP_002388;NP_001180276;NP_001124477;NP_001180279;NP_001180278;NP_001180277" "NM_002397;NM_001193347;NM_001131005;NM_001193350;NM_001193349;NM_001193348" "ENSP00000389610;ENSP00000340874;ENSP00000421925" candidate 0 0 0 Eukaryotes 44 3 Cellular metabolism,DNA/RNA metabolism and transcription,Development,Regulation of intracellular processes and metabolism,Regulation of transcription 83 chr5 88018424 88119605 WES head and neck squamous cell carcinoma,lymphoma MEI1 150365 meiosis inhibitor 1 22q13.2 - 28613 608797 NP_689726 NM_152513 ENSP00000384115 candidate 0 0 0 Metazoans 1 0 -1 -1 chr22 42095543 42195300 WGS melanoma MEN1 4221 multiple endocrine neoplasia I 11q13 564 7010 613733 "NP_570713;NP_570714;NP_570715;NP_000235;NP_570716;NP_570712;NP_570711" "NM_130801;NM_130802;NM_130803;NM_000244;NM_130804;NM_130800;NM_130799" "ENSP00000396940;ENSP00000308975;ENSP00000366538;ENSP00000377899;ENSP00000337088;ENSP00000377901" known 0 1 0 Eukaryotes 18 0 Cell cycle,Cell response to stimuli,Cellular metabolism,Cellular processes,DNA/RNA metabolism and transcription,Development,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction 102 chr11 64571809 64577581 CGC,WES pancreas,thyroid MEP1A 4224 meprin A, alpha (PABA peptide hydrolase) 6p12-p11 2666 7015 600388 NP_005579 NM_005588 ENSP00000230588 candidate 0 0 0 Eukaryotes 21 1 Cellular metabolism 4 chr6 46761136 46806870 WES pancreas MEPE 56955 matrix extracellular phosphoglycoprotein 4q21.1 6908 13361 605912 "NP_001171624;NP_064588;NP_001171625;NP_001171626;NP_001171623" "NM_001184695;NM_020203;NM_001184696;NM_001184697;NM_001184694" "ENSP00000416984;ENSP00000443491;ENSP00000453994;ENSP00000354341" candidate 0 0 0 Mammals 9 4 Development 7 chr4 88755867 88767595 WGS lung MET 4233 met proto-oncogene (hepatocyte growth factor receptor) 7q31 1280 7029 164860 "NP_000236;NP_001120972" "NM_000245;NM_001127500" ENSP00000380860 known 1 0 0 Last Universal Common Ancestor 76 17 Cell cycle,Cell motility and interactions,Cellular metabolism,Cellular processes,Development,Multicellular activities,Regulation of intracellular processes and metabolism,Signal transduction 85 chr7 116339139 116436175 CGC,Amplified head and neck squamous cell carcinoma,kidney METAP2 10988 methionyl aminopeptidase 2 12q22 3522 16672 601870 NP_006829 NM_006838 ENSP00000325312 candidate 0 0 0 Last Universal Common Ancestor 0 8 Cellular metabolism,Cellular processes 81 chr12 95867956 95907677 WGS prostate METTL17 64745 methyltransferase like 17 14q11.2 13379 19280 - "NP_073571;NP_001025162" "NM_022734;NM_001029991;NM_001029992" "ENSP00000372445;ENSP00000343041" candidate 0 0 0 Last Universal Common Ancestor 11 0 -1 33 chr14 21458162 21465039 WGS prostate METTL3 56339 methyltransferase like 3 14q11.1 14389 17563 612472 NP_062826 NM_019852 ENSP00000298717 candidate 0 0 0 Last Universal Common Ancestor 3 0 Cellular metabolism,DNA/RNA metabolism and transcription 98 chr14 21966405 21979365 WES gastric MFSD8 256471 major facilitator superfamily domain containing 8 4q28.2 14557 28486 611124 NP_689991 NM_152778 ENSP00000296468 candidate 0 0 0 Eukaryotes 0 0 -1 -1 chr4 128841788 128886288 WGS liver MGA 23269 MAX gene associated 15q14 - 14010 - "NP_001157745;NP_001074010" "NM_001164273;NM_001080541" "ENSP00000442467;ENSP00000219905" candidate 0 0 0 Last Universal Common Ancestor 6 2 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription 6 chr15 41961093 42059475 WGS chronic lymphocytic leukemia MGAM 8972 maltase-glucoamylase (alpha-glucosidase) 7q34 1104 7043 154360 NP_004659 NM_004668 ENSP00000447378 candidate 0 0 0 Last Universal Common Ancestor 14 0 Cellular metabolism 4 chr7 141705331 141805688 WGS prostate MICAL3 57553 microtubule associated monoxygenase, calponin and LIM domain containing 3 22q11.21 - 24694 608882 "NP_001116203;NP_001129476;NP_056056" "NM_001122731;NM_001136004;NM_015241" "ENSP00000410315;ENSP00000414846;ENSP00000416015" candidate 0 0 0 Eukaryotes 2 0 -1 34 chr22 18273501 18389578 WGS glioblastoma MIER3 166968 mesoderm induction early response 1, family member 3 5q11.2 8199 26678 - NP_689835 NM_152622 ENSP00000370611 candidate 0 0 0 Eukaryotes 1 9 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription -1 chr5 56218958 56242902 WES colorectal (hypermutated) MITF 4286 microphthalmia-associated transcription factor 3p14.2-p14.1 1138 7105 156845 "NP_000239;NP_937802;NP_937821;NP_001171897;NP_006713;NP_001171896;NP_937801;NP_937820" "NM_000248;NM_198159;NM_198178;NM_001184968;NM_006722;NM_001184967;NM_198158;NM_198177" "ENSP00000377884;ENSP00000327867;ENSP00000295600" known 1 0 0 Opisthokonts 4 5 Cell response to stimuli,Cellular metabolism,DNA/RNA metabolism and transcription,Development,Regulation of intracellular processes and metabolism,Regulation of transcription 69 chr3 69788749 70014396 CGC,Amplified melanoma MKL1 57591 megakaryoblastic leukemia (translocation) 1 22q13 10445 14334 606078 NP_065882 NM_020831 ENSP00000347847 known 1 0 0 Opisthokonts 64 0 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription 83 chr22 40807397 40831556 CGC leukemia MKRN3 7681 makorin ring finger protein 3 15q11-q13 4836 7114 603856 NP_005655 NM_005664 ENSP00000313881 candidate 0 0 0 Eukaryotes 49 0 -1 7 chr15 23810930 23812450 HTMS,WES breast,lung,ovarian,pancreas,prostate,colorectal MLF1 4291 myeloid leukemia factor 1 3q25.1 3239 7125 601402 "NP_001182361;NP_001123628;NP_001182362;NP_071888;NP_001182363;NP_001123629" "NM_001195432;NM_001130156;NM_001195433;NM_022443;NM_001195434;NM_001130157" "ENSP00000352025;ENSP00000348157" known 1 0 0 Eukaryotes 11 0 Cell cycle,Cellular metabolism,DNA/RNA metabolism and transcription,Development 62 chr3 158310221 158322988 CGC leukemia MLH1 4292 mutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli) 3p21.3 390 7127 120436 "NP_001161091;NP_001161089;NP_001161090;NP_000240" "NM_001167619;NM_001167617;NM_001167618;NM_000249" "ENSP00000231790;ENSP00000402564;ENSP00000398272;ENSP00000443665;ENSP00000416687;ENSP00000402667" known 0 1 0 Last Universal Common Ancestor 145 3 Cell cycle,Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism 107 chr3 37035039 37092141 CGC central nervous system,colorectal,endometrium,ovarian MLL 4297 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila) 11q23 1162 7132 159555 "NP_001184033;NP_005924" "NM_024891;NM_001197104;NM_005933" "ENSP00000436786;ENSP00000374157" known 1 0 0 Last Universal Common Ancestor 99 5 Cell cycle,Cellular metabolism,DNA/RNA metabolism and transcription,Development,Regulation of intracellular processes and metabolism,Regulation of transcription 93 chr11 118307228 118392884 CGC,WES,WGS leukemia,bladder,medulloblastoma,prostate,liver MLL2 8085 myeloid/lymphoid or mixed-lineage leukemia 2 12q13.12 3664 7133 602113 NP_003473 NM_003482 ENSP00000301067 known 0 1 0 Last Universal Common Ancestor 60 7 Cellular metabolism,DNA/RNA metabolism and transcription,Development,Regulation of intracellular processes and metabolism,Regulation of transcription 23 chr12 49415566 49449107 CGC,HTMS,WES,WGS kidney,medulloblastoma,breast,head and neck squamous cell carcinoma,lung,lymphoma,non-hodgkin lymphoma,prostate MLL3 58508 myeloid/lymphoid or mixed-lineage leukemia 3 7q36.1 6016 13726 606833 NP_733751 "NM_021230;NM_170606" ENSP00000262189 known 0 1 0 Last Universal Common Ancestor 27 4 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction -1 chr7 151833920 152132871 CGC,WES,WGS medulloblastoma,bladder,breast,cholangiocarcinoma,pancreas,prostate,liver MLLT1 4298 "myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 1" 19p13.3 15933 7134 159556 NP_005925 NM_005934 - known 1 0 0 Last Universal Common Ancestor 32 3 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription 0 chr19 6213056 6270773 CGC leukemia MLLT10 8028 "myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10" 10p12 3874 16063 602409 "NP_001182557;NP_004632;NP_001182559;NP_001182556;NP_001182555" "NM_001009569;NM_001195628;NM_004641;NM_001195630;NM_001195627;NM_001195626" "ENSP00000307411;ENSP00000366304;ENSP00000366272" known 1 0 0 Eukaryotes 14 1 -1 88 chr10 21823574 22030909 CGC leukemia MLLT11 10962 "myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11" 1q21 5251 16997 604684 NP_006809 NM_006818 - known 1 0 0 Vertebrates 0 4 -1 91 chr1 151039701 151039970 CGC leukemia MLLT3 4300 "myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3" 9p22 1163 7136 159558 NP_004520 NM_004529 - known 1 0 0 Last Universal Common Ancestor 45 3 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription 63 chr9 20346444 20620833 CGC leukemia MLLT4 4301 "myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4" 6q27 1164 7137 159559 "NP_001035089;NP_001193937" "NM_001040000;NM_001207008;NM_001040001;NM_005936" "ENSP00000375956;ENSP00000375960" known 1 0 0 Eukaryotes 73 4 Signal transduction 20 chr6 168227813 168370612 CGC leukemia MLLT6 4302 "myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 6" 17q21 8978 7138 600328 NP_005928 NM_005937 ENSP00000316426 known 1 0 0 Eukaryotes 14 5 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription -1 chr17 36861886 36881848 CGC,HTMS leukemia,breast,lung,ovarian,pancreas,prostate MMP11 4320 matrix metallopeptidase 11 (stromelysin 3) 22q11.2|22q11.23 1705 7157 185261 NP_005931 NM_005940 ENSP00000215743 candidate 0 0 0 Eukaryotes 2 1 Cellular metabolism 47 chr22 24115058 24125728 WGS melanoma MMP2 4313 matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase) 16q13-q21 386 7166 120360 "NP_004521;NP_001121363" "NM_004530;NM_001127891" ENSP00000219070 candidate 0 0 0 Eukaryotes 45 5 Cellular metabolism,Development 96 chr16 55513392 55539351 WES colorectal MN1 4330 meningioma (disrupted in balanced translocation) 1 22q11|22q12.1 8862 7180 156100 NP_002421 NM_002430 ENSP00000304956 known 1 0 0 Metazoans 1 4 Cell cycle,Regulation of intracellular processes and metabolism 66 chr22 28146906 28196531 CGC leukemia,meningioma MNAT1 4331 menage a trois homolog 1, cyclin H assembly factor (Xenopus laevis) 14q23 4042 7181 602659 "NP_002422;NP_001171434" "NM_002431;NM_001177963" ENSP00000446437 candidate 0 0 0 Eukaryotes 84 1 Cell cycle,Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction 5 chr14 61201581 61435064 HTMS breast,lung,ovarian,pancreas,prostate MNX1 3110 motor neuron and pancreas homeobox 1 7q36 874 4979 142994 "NP_001158727;NP_005506" "NM_001165255;NM_005515" "ENSP00000438552;ENSP00000252971" known 1 0 0 Metazoans 0 2 Cell cycle,Cellular metabolism,DNA/RNA metabolism and transcription,Development,Regulation of intracellular processes and metabolism,Regulation of transcription 17 chr7 156798217 156803044 CGC leukemia MOB3B 79817 MOB kinase activator 3B 9p21.2 14728 23825 - NP_079037 NM_024761 ENSP00000262244 candidate 0 0 2 Eukaryotes 9 6 -1 54 chr9 27359032 27455548 WGS glioblastoma MOCS1 4337 molybdenum cofactor synthesis 1 6p21.3 4749 7190 603707 "NP_001068566;NP_005934" "NM_005942;NR_033233;NM_138928;NM_001075098;NM_005943" "ENSP00000362284;ENSP00000362282" candidate 0 0 1 Last Universal Common Ancestor 1 0 Cellular metabolism 51 chr6 39876826 39902156 WGS liver MORC1 27136 MORC family CW-type zinc finger 1 3q13 4439 7198 603205 NP_055244 NM_014429 ENSP00000232603 candidate 0 0 0 Last Universal Common Ancestor 1 0 Development,Multicellular activities 1 chr3 108677815 108836906 WGS breast MOS 4342 v-mos Moloney murine sarcoma viral oncogene homolog 8q11 1816 7199 190060 NP_005363 NM_005372 ENSP00000310722 candidate 0 0 0 Last Universal Common Ancestor 6 0 Cellular metabolism,Cellular processes 58 chr8 57025504 57026541 HTMS sarcoma MPL 4352 myeloproliferative leukemia virus oncogene 1p34 1161 7217 159530 NP_005364 NM_005373 - known 1 0 0 Vertebrates 11 0 Signal transduction 19 chr1 43803520 43818440 CGC myeloma MPPED2 744 metallophosphoesterase domain containing 2 11p13 2947 1180 600911 "NP_001575;NP_001138871" "NM_001584;NM_001145399" "ENSP00000388258;ENSP00000350833" candidate 0 0 1 Last Universal Common Ancestor 1 1 Development 48 chr11 30433018 30601920 WGS melanoma MRE11A 4361 MRE11 meiotic recombination 11 homolog A (S. cerevisiae) 11q21 2889 7230 600814 "NP_005581;NP_005582" "NM_005590;NM_005591" - candidate 0 0 1 Last Universal Common Ancestor 49 7 Cell cycle,Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription 14 chr11 94153294 94224130 WES breast MRPL18 29074 mitochondrial ribosomal protein L18 6q25.3 14744 14477 611831 NP_054880 NM_014161 ENSP00000356001 candidate 0 0 0 Eukaryotes 2 2 Cellular metabolism,Regulation of transcription 109 chr6 160211620 160219152 WGS glioblastoma MSH2 4436 mutS homolog 2, colon cancer, nonpolyposis type 1 (E. coli) 2p21 389 7325 609309 NP_000242 NM_000251 "ENSP00000233146;ENSP00000442697" known 0 1 0 Last Universal Common Ancestor 19 8 Cell cycle,Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism 45 chr2 47630331 47710085 CGC colorectal,endometrium,ovarian MSH3 4437 mutS homolog 3 (E. coli) 5q11-q12 2931 7326 600887 NP_002430 NM_002439 ENSP00000265081 candidate 0 0 0 Last Universal Common Ancestor 24 1 Cellular metabolism,DNA/RNA metabolism and transcription,Development,Immune system response 74 chr5 79950547 80171678 WES colorectal (hypermutated) MSH6 2956 mutS homolog 6 (E. coli) 2p16 7202 7329 600678 NP_000170 NM_000179 ENSP00000234420 known 0 1 0 Last Universal Common Ancestor 59 7 Cellular metabolism,DNA/RNA metabolism and transcription 76 chr2 48010373 48033996 CGC,WES colorectal,colorectal (hypermutated) MSI2 124540 musashi homolog 2 (Drosophila) 17q22 7438 18585 607897 "NP_620412;NP_733839" "NM_138962;NM_170721" ENSP00000313616 known 1 0 0 Last Universal Common Ancestor 7 1 -1 -1 chr17 55334104 55752487 CGC,HTMS leukemia,breast,lung,ovarian,pancreas,prostate MSN 4478 moesin Xq11.1 2399 7373 309845 NP_002435 NM_002444 ENSP00000353408 known 1 0 2 Eukaryotes 63 2 Cell motility and interactions,Immune system response 106 chrX 64936680 64959752 CGC lymphoma MST1 4485 macrophage stimulating 1 (hepatocyte growth factor-like) 3p21 798 7380 142408 NP_066278 NM_020998 ENSP00000414287 candidate 0 0 2 Last Universal Common Ancestor 6 1 Cellular metabolism,Multicellular activities 60 chr3 49721464 49726124 WGS melanoma MST1R 4486 macrophage stimulating 1 receptor (c-met-related tyrosine kinase) 3p21.3 2545 7381 600168 "NP_002438;NP_001231866" "NM_002447;NM_001244937" "ENSP00000341325;ENSP00000296474" candidate 0 0 0 Last Universal Common Ancestor 32 0 Cell cycle,Cellular metabolism,Cellular processes,Development,Regulation of intracellular processes and metabolism,Signal transduction 50 chr3 49924743 49941042 HTMS sarcoma MTA1 9112 metastasis associated 1 14q32.3 4633 7410 603526 "NP_001190187;NP_004680" "NM_001203258;NM_004689" ENSP00000333633 candidate 0 0 0 Metazoans 76 2 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction 104 chr14 105905008 105936549 WGS lung MTA2 9219 metastasis associated 1 family, member 2 11q12-q13.1 7233 7411 603947 NP_004730 NM_004739 ENSP00000278823 candidate 0 0 0 Metazoans 76 5 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription 10 chr11 62361350 62368162 WGS lung MTCP1 4515 mature T-cell proliferation 1 Xq28 2122 7423 300116 NP_001018025 "NM_001018025;NM_014221" ENSP00000358488 known 1 0 0 Last Universal Common Ancestor 6 1 -1 21 chrX 154293768 154294285 CGC leukemia MTDH 92140 metadherin 8q22.1 17459 29608 610323 NP_848927 NM_178812 ENSP00000338235 known 0 0 0 Metazoans 15 8 -1 108 chr8 98656735 98736895 CGC,WGS,Amplified liver MTMR11 10903 myotubularin related protein 11 1q12-q21 16748 24307 - "NP_870988;NP_001139334" "NM_181873;NM_006697;NM_001145862" "ENSP00000391668;ENSP00000358136" candidate 0 0 0 Eukaryotes 1 0 -1 70 chr1 149901024 149908540 WGS prostate MTMR8 55613 myotubularin related protein 8 Xq11.2 6664 16825 - NP_060147 NM_017677 ENSP00000363985 candidate 0 0 0 Eukaryotes 3 0 Cellular metabolism,Cellular processes 74 chrX 63488420 63579407 WES lymphoma MTUS2 23281 microtubule associated tumor suppressor candidate 2 13q12.3 11108 20595 - "NP_056048;NP_001028774" "NM_015233;NM_001033602" - candidate 0 0 0 Metazoans 35 4 -1 8 chr13 29598806 30077340 WES breast,glioblastoma,pancreas MUC1 4582 mucin 1, cell surface associated 1q21 1152 7508 158340 "NP_002447;NP_001037857;NP_001018017;NP_001191216;NP_001191225;NP_001037858;NP_001191223;NP_001191220;NP_001191222;NP_001191224;NP_001191215;NP_001191226;NP_001191219;NP_001037855;NP_001191214;NP_001037856;NP_001191218;NP_001191217;NP_001018016;NP_001191221" "NM_002456;NM_001018021;NM_001044392;NM_001018017;NM_001204287;NM_001204296;NM_182741;NM_001044393;NM_001204294;NM_001204291;NM_001204293;NM_001204295;NM_001204286;NM_001204297;NM_001204290;NM_001044390;NM_001204285;NM_001044391;NM_001204289;NM_001204288;NM_001018016;NM_001204292" "ENSP00000357377;ENSP00000357380;ENSP00000343482;ENSP00000357378" known 1 0 0 Vertebrates 35 9 -1 91 chr1 155158614 155162634 CGC non-hodgkin lymphoma MUC16 94025 mucin 16, cell surface associated 19p13.2 - 15582 606154 NP_078966 NM_024690 ENSP00000381008 candidate 0 0 0 Last Universal Common Ancestor 3 0 -1 1 chr19 9056228 9091814 HTMS breast,lung,ovarian,pancreas,prostate MUC17 140453 mucin 17, cell surface associated 7q22.1 16335 16800 608424 NP_001035194 "NM_001004430;NM_001040105" ENSP00000302716 candidate 0 0 0 Last Universal Common Ancestor 0 7 -1 -1 chr7 100663417 100699557 WGS breast MUC2 4583 mucin 2, oligomeric mucus/gel-forming 11p15.5 11828 7512 158370 NP_002448 NM_002457 ENSP00000415183 candidate 0 0 0 Last Universal Common Ancestor 7 0 Multicellular activities 28 chr11 1074902 1104260 WES chronic lymphocytic leukemia MUC4 4585 mucin 4, cell surface associated 3q29 11829 7514 158372 "NP_612154;NP_004523;NP_060876" "NM_138297;NM_138299;NM_138298;NM_004532;NM_018406" "ENSP00000304207;ENSP00000417498;ENSP00000338109" candidate 0 0 0 Last Universal Common Ancestor 3 2 Cell motility and interactions 18 chr3 195474050 195518372 WGS melanoma MUC5B 727897 mucin 5B, oligomeric mucus/gel-forming 11p15.5 - 7516 600770 NP_002449 NM_002458 ENSP00000436812 candidate 0 0 0 Last Universal Common Ancestor 9 1 -1 3 chr11 1244354 1282835 WGS liver MUTYH 4595 mutY homolog (E. coli) 1p34.1 5380 7527 604933 "NP_001041638;NP_001041636;NP_036354;NP_001041639;NP_001121897;NP_001041637" "NM_001048173;NM_001048171;NM_012222;NM_001048174;NM_001128425;NM_001048172" "ENSP00000361187;ENSP00000346354;ENSP00000347685;ENSP00000407590;ENSP00000408176;ENSP00000361170" known 0 1 0 Last Universal Common Ancestor 13 0 Cell cycle,Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism 86 chr1 45794981 45800183 CGC MX2 4600 myxovirus (influenza virus) resistance 2 (mouse) 21q22.3 1001 7533 147890 NP_002454 NM_002463 ENSP00000333657 candidate 0 0 0 Last Universal Common Ancestor 1 1 Cell response to stimuli 99 chr21 42748834 42780157 WGS lung MYB 4602 v-myb myeloblastosis viral oncogene homolog (avian) 6q22-q23 1810 7545 189990 "NP_001155129;NP_001155130;NP_001155132;NP_005366;NP_001155128;NP_001123644;NP_001155131;NP_001123645" "NM_001161657;NM_001161658;NM_001161660;NM_005375;NM_001161656;NM_001130172;NM_001161659;NM_001130173" "ENSP00000410825;ENSP00000339992;ENSP00000435938;ENSP00000356788" known 1 0 0 Eukaryotes 91 14 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription 34 chr6 135507039 135539115 CGC adenoid cystic carcinoma MYC 4609 v-myc myelocytomatosis viral oncogene homolog (avian) 8q24.21 1818 7553 190080 NP_002458 NM_002467 ENSP00000367207 known 1 0 0 Eukaryotes 990 24 Cell cycle,Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription 61 chr8 128750491 128753201 CGC,WES,WGS,Amplified leukemia,lymphoma,lung MYCBP2 23077 MYC binding protein 2 13q22 10104 23386 610392 NP_055872 NM_015057 ENSP00000384288 candidate 0 0 0 Eukaryotes 29 1 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription 87 chr13 77619516 77900910 WGS breast MYCL1 4610 v-myc myelocytomatosis viral oncogene homolog 1, lung carcinoma derived (avian) 1p34.2 1279 7555 164850 "NP_001028253;NP_001028254;NP_005367" "NM_001033081;NM_001033082;NM_005376" "ENSP00000380494;ENSP00000361902" known 1 0 1 Opisthokonts 2 1 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription 84 chr1 40363047 40367560 CGC,WGS,Amplified lung,liver MYCN 4613 v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian) 2p24.3 1278 7559 164840 NP_005369 NM_005378 ENSP00000281043 known 1 0 0 Eukaryotes 23 12 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription 11 chr2 16082187 16086216 CGC,Amplified neuroblastoma MYD88 4615 myeloid differentiation primary response gene (88) 3p22 3703 7562 602170 "NP_001166037;NP_001166039;NP_001166038;NP_002459;NP_001166040" "NM_001172566;NM_001172568;NM_001172567;NM_002468;NM_001172569" "ENSP00000401399;ENSP00000379625" known 1 0 0 Metazoans 66 1 Cell cycle,Cell response to stimuli,Cellular metabolism,DNA/RNA metabolism and transcription,Development,Immune system response,Multicellular activities,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction 109 chr3 38180153 38182774 CGC,WES,WGS lymphoma,chronic lymphocytic leukemia,non-hodgkin lymphoma MYH1 4619 myosin, heavy chain 1, skeletal muscle, adult 17p13.1 8872 7567 160730 NP_005954 NM_005963 ENSP00000226207 candidate 0 0 6 Last Universal Common Ancestor 11 1 Multicellular activities 14 chr17 10395736 10419959 WES breast MYH11 4629 myosin, heavy chain 11, smooth muscle 16p13.11 1174 7569 160745 "NP_001035203;NP_074035;NP_001035202;NP_002465" "NM_001040114;NM_022844;NM_001040113;NM_002474" "ENSP00000407821;ENSP00000379616;ENSP00000300036;ENSP00000345136" known 1 0 2 Last Universal Common Ancestor 24 0 Cell cycle,Cell motility and interactions,Cellular processes,Development,Multicellular activities 52 chr16 15797851 15932109 CGC leukemia MYH2 4620 myosin, heavy chain 2, skeletal muscle, adult 17p13.1 1173 7572 160740 "NP_001093582;NP_060004" "NM_001100112;NM_017534" "ENSP00000380367;ENSP00000245503" candidate 0 0 7 Last Universal Common Ancestor 14 1 Cellular processes,Multicellular activities 34 chr17 10424600 10451237 WES pancreas MYH4 4622 myosin, heavy chain 4, skeletal muscle 17p13.1 8873 7574 160742 NP_060003 NM_017533 ENSP00000255381 candidate 0 0 7 Last Universal Common Ancestor 3 1 Cellular processes,Multicellular activities 4 chr17 10346695 10370062 WES pancreas MYH6 4624 myosin, heavy chain 6, cardiac muscle, alpha 14q12 1171 7576 160710 NP_002462 NM_002471 ENSP00000386041 candidate 0 0 5 Last Universal Common Ancestor 2 0 Cellular processes,Development,Multicellular activities 6 chr14 23851637 23876432 WGS glioblastoma MYH8 4626 myosin, heavy chain 8, skeletal muscle, perinatal 17p13.1 11760 7578 160741 NP_002463 NM_002472 ENSP00000384330 candidate 0 0 7 Last Universal Common Ancestor 6 0 Multicellular activities 24 chr17 10293774 10323544 WGS breast MYH9 4627 myosin, heavy chain 9, non-muscle 22q13.1 1177 7579 160775 NP_002464 NM_002473 ENSP00000216181 known 1 0 2 Last Universal Common Ancestor 109 6 Cell motility and interactions,Cell response to stimuli,Cellular metabolism,Cellular processes,Development,Immune system response,Regulation of intracellular processes and metabolism,Signal transduction 104 chr22 36678717 36745281 CGC,WES lymphoma,breast MYLK4 340156 myosin light chain kinase family, member 4 6p25.2 17355 27972 - NP_001012418 NM_001012418 ENSP00000274643 candidate 0 0 0 Last Universal Common Ancestor 2 0 Cellular metabolism,Cellular processes -1 chr6 2671538 2749528 WES breast MYO18B 84700 myosin XVIIIB 22q12.1 9529 18150 607295 NP_115997 NM_032608 ENSP00000334563 candidate 0 0 0 Last Universal Common Ancestor 6 0 -1 -1 chr22 26157060 26423641 WES,WGS breast,colorectal,prostate MYO19 80179 myosin XIX 17q12 10107 26234 - "NP_001157207;NP_001028752;NP_079385" "NM_001163735;NM_001033580;NM_025109;NM_001033579" "ENSP00000409936;ENSP00000268852" candidate 0 0 0 Last Universal Common Ancestor 13 4 -1 51 chr17 34852098 34884042 WES colorectal MYO1B 4430 myosin IB 2q12-q34 8407 7596 606537 "NP_001123630;NP_001155291;NP_036355" "NM_001130158;NM_001161819;NM_012223" "ENSP00000376132;ENSP00000306382;ENSP00000341903" candidate 0 0 0 Last Universal Common Ancestor 12 2 -1 93 chr2 192141622 192288683 WES colorectal (hypermutated),glioblastoma MYO1G 64005 myosin IG 7p13-p11.2 17622 13880 613445 NP_149043 NM_033054 ENSP00000258787 candidate 0 0 0 Last Universal Common Ancestor 7 0 -1 -1 chr7 45002341 45018560 WES breast,lymphoma MYO3A 53904 myosin IIIA 10p11.1 6008 7601 606808 NP_059129 NM_017433 ENSP00000265944 candidate 0 0 0 Last Universal Common Ancestor 2 0 Cell response to stimuli,Cellular metabolism,Cellular processes 5 chr10 26241040 26500889 WGS prostate MYO5B 4645 myosin VB 18q21 - 7603 606540 NP_001073936 NM_001080467 ENSP00000285039 candidate 0 0 0 Last Universal Common Ancestor 11 4 -1 -1 chr18 47352844 47581751 WGS lymphoma MYO5C 55930 myosin VC 15q21 11380 7604 610022 NP_061198 NM_018728 ENSP00000261839 candidate 0 0 0 Last Universal Common Ancestor 5 0 -1 98 chr15 52486102 52575092 WES colorectal MYO9A 4649 myosin IXA 15q22-q23 5341 7608 604875 NP_008832 NM_006901 ENSP00000398250 candidate 0 0 0 Last Universal Common Ancestor 6 6 Cell response to stimuli,Signal transduction 61 chr15 72118924 72338904 WGS melanoma MYOM2 9172 myomesin (M-protein) 2, 165kDa 8p23.3 4619 7614 603509 NP_003961 NM_003970 ENSP00000262113 candidate 0 0 0 Last Universal Common Ancestor 17 0 Multicellular activities 30 chr8 1998881 2092902 WES lymphoma MYOM3 127294 myomesin family, member 3 1p36.11 8200 26679 - NP_689585 NM_152372 ENSP00000363557 candidate 0 0 0 Eukaryotes 2 0 -1 -1 chr1 24383857 24435126 WES pancreas NAB2 4665 NGFI-A binding protein 2 (EGR1 binding protein 2) 12q13.3 3854 7627 602381 NP_005958 NM_005967 ENSP00000300131 candidate 0 0 0 Metazoans 9 1 Cellular metabolism,DNA/RNA metabolism and transcription,Development,Regulation of intracellular processes and metabolism,Regulation of transcription 36 chr12 57483055 57488501 WGS lymphoma NACA 4666 nascent polypeptide-associated complex alpha subunit 12q23-q24.1 3137 7629 601234 "NP_001106674;NP_001106672;NP_005585;NP_001106673" "NM_001113203;NM_001113201;NM_005594;NR_045277;NM_001113202" ENSP00000448035 known 1 0 0 Last Universal Common Ancestor 32 2 Cellular metabolism,Cellular processes,DNA/RNA metabolism and transcription,Regulation of transcription 109 chr12 57106570 57118305 CGC non-hodgkin lymphoma NALCN 259232 sodium leak channel, non-selective 13q32.3 15647 19082 611549 NP_443099 NM_052867 ENSP00000251127 candidate 0 0 0 Eukaryotes 1 1 Cellular processes -1 chr13 101707650 102051477 WES,WGS pancreas,breast NAT10 55226 N-acetyltransferase 10 (GCN5-related) 11p13 10964 29830 609221 "NP_001137502;NP_078938" "NM_001144030;NM_024662" "ENSP00000433011;ENSP00000257829" candidate 0 0 0 Last Universal Common Ancestor 23 1 -1 106 chr11 34129773 34167736 WGS prostate NAT2 10 N-acetyltransferase 2 (arylamine N-acetyltransferase) 8p22 2000 7646 612182 NP_000006 NM_000015 ENSP00000286479 candidate 0 0 1 Last Universal Common Ancestor 2 0 -1 18 chr8 18257514 18258383 WGS melanoma NAV3 89795 neuron navigator 3 12q14.3 10114 15998 611629 NP_055718 NM_014903 ENSP00000381007 candidate 0 0 0 Eukaryotes 30 0 -1 32 chr12 78225242 78604294 WES colorectal,head and neck squamous cell carcinoma,kidney NBEAL1 65065 neurobeachin-like 1 2q33.2 14811 20681 609816 NP_001107604 "NM_198945;NM_205543;NM_001114132;NM_001099273" ENSP00000399903 candidate 0 0 0 Last Universal Common Ancestor 1 0 -1 -1 chr2 203881108 204082074 WGS prostate NBN 4683 nibrin 8q21 4050 7652 602667 NP_002476 "NM_001024688;NM_002485" ENSP00000265433 known 0 1 0 Opisthokonts 62 3 Cell cycle,Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction 101 chr8 90949253 90996789 CGC NCAM2 4685 neural cell adhesion molecule 2 21q21.1 3619 7657 602040 NP_004531 NM_004540 - candidate 0 0 0 Eukaryotes 4 2 Cell motility and interactions 44 chr21 22370882 22910275 WES lung NCKIPSD 51517 NCK interacting protein with SH3 domain 3p21 9450 15486 606671 "NP_057537;NP_909119" "NM_016453;NM_184231" "ENSP00000294129;ENSP00000389059" known 1 0 0 Opisthokonts 28 1 Cellular processes,Signal transduction 90 chr3 48711980 48723240 CGC leukemia NCOA1 8648 nuclear receptor coactivator 1 2p23 4070 7668 602691 "NP_003734;NP_671766;NP_671756" "NM_003743;NM_147233;NM_147223" "ENSP00000320940;ENSP00000288599;ENSP00000379197" known 1 0 0 Eukaryotes 93 0 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction 104 chr2 24881547 24991257 CGC sarcoma NCOA2 10499 nuclear receptor coactivator 2 8q13.3 9066 7669 601993 NP_006531 NM_006540 - known 1 0 0 Eukaryotes 11 1 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction 62 chr8 71033537 71128980 CGC leukemia,sarcoma NCOA3 8202 nuclear receptor coactivator 3 20q12 3570 7670 601937 "NP_006525;NP_001167559;NP_858045;NP_001167558" "NM_006534;NM_001174088;NM_181659;NM_001174087" "ENSP00000361065;ENSP00000361073" known 0 0 0 Eukaryotes 116 12 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction 100 chr20 46250992 46281816 CGC,Amplified NCOA4 8031 nuclear receptor coactivator 4 10q11.2 3584 7671 601984 "NP_001138735;NP_001138733;NP_001138734;NP_001138732;NP_005428" "NM_001145263;NM_001145261;NM_001145262;NM_001145260;NM_005437" "ENSP00000395465;ENSP00000405146;ENSP00000390713;ENSP00000363200;ENSP00000344552" known 1 0 3 Metazoans 17 0 Cellular metabolism,DNA/RNA metabolism and transcription,Development,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction 109 chr10 51568357 51586672 CGC thyroid NCOA6 23054 nuclear receptor coactivator 6 20q11 5599 15936 605299 "NP_001229468;NP_054790" "NM_001242539;NM_014071" ENSP00000351894 candidate 0 0 0 Last Universal Common Ancestor 85 4 Cellular metabolism,DNA/RNA metabolism and transcription,Development,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction 106 chr20 33303129 33370158 WES breast NCOR1 9611 nuclear receptor corepressor 1 17p11.2 2911 7672 600849 "NP_006302;NP_001177367;NP_001177369" "NM_006311;NM_001190438;NM_001190440" "ENSP00000379189;ENSP00000379192;ENSP00000268712" candidate 0 0 0 Last Universal Common Ancestor 174 0 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription 104 chr17 15935613 16097883 WES,WGS bladder,breast,prostate,lymphoma NDC80 10403 NDC80 kinetochore complex component homolog (S. cerevisiae) 18p11.32 6277 16909 607272 NP_006092 NM_006101 ENSP00000261597 candidate 0 0 0 Eukaryotes 22 1 Cell cycle,Cellular processes,DNA/RNA metabolism and transcription,Signal transduction 7 chr18 2572985 2616570 WES cholangiocarcinoma NDRG1 10397 N-myc downstream regulated 1 8q24.3 5586 7679 605262 "NP_006087;NP_001128714" "NM_006096;NM_001135242" "ENSP00000404854;ENSP00000437443;ENSP00000319977" known 1 0 0 Eukaryotes 59 2 Cell response to stimuli 107 chr8 134251124 134296554 CGC prostate NEB 4703 nebulin 2q22 1196 7720 161650 "NP_004534;NP_001157980;NP_001157979" "NM_004543;NM_001164508;NM_001164507" "ENSP00000416578;ENSP00000380505;ENSP00000386259" candidate 0 0 0 Last Universal Common Ancestor 33 0 Cellular processes,Development,Regulation of intracellular processes and metabolism 34 chr2 152357902 152584420 WES lymphoma NEFH 4744 neurofilament, heavy polypeptide 22q12.2 1204 7737 162230 NP_066554 NM_021076 ENSP00000311997 candidate 0 0 0 Last Universal Common Ancestor 7 3 DNA/RNA metabolism and transcription,Development 45 chr22 29876252 29886689 WGS prostate NEK2 4751 NIMA (never in mitosis gene a)-related kinase 2 1q32.2-q41 4953 7745 604043 "NP_001191112;NP_002488;NP_001191111" "NM_001204183;NM_002497;NM_001204182" "ENSP00000355965;ENSP00000355966" candidate 0 0 4 Last Universal Common Ancestor 38 2 Cell cycle,Cellular metabolism,Cellular processes 36 chr1 211836771 211848821 HTMS breast,lung,ovarian,pancreas,prostate NEK8 284086 NIMA (never in mitosis gene a)- related kinase 8 17q11.1 14822 13387 609799 NP_835464 NM_178170 - candidate 0 0 0 Last Universal Common Ancestor 9 0 Cellular metabolism,Cellular processes -1 chr17 27055832 27068588 WGS liver NEK9 91754 NIMA (never in mitosis gene a)- related kinase 9 14q24.3 11386 18591 609798 NP_149107 NM_033116 ENSP00000238616 candidate 0 0 0 Last Universal Common Ancestor 27 4 Cell cycle,Cellular metabolism,Cellular processes 92 chr14 75551270 75593624 WGS lung NETO2 81831 neuropilin (NRP) and tolloid (TLL)-like 2 16q11 9721 14644 607974 "NP_060562;NP_001188406" "NM_018092;NM_001201477" ENSP00000306726 candidate 0 0 1 Metazoans 1 6 -1 47 chr16 47117135 47165937 WES head and neck squamous cell carcinoma NEUROG2 63973 neurogenin 2 4q25 6976 13805 606624 NP_076924 NM_024019 ENSP00000317333 candidate 0 0 0 Metazoans 2 0 Cell cycle,Cell motility and interactions,Cellular metabolism,DNA/RNA metabolism and transcription,Development,Regulation of intracellular processes and metabolism,Regulation of transcription 0 chr4 113435816 113436631 WES melanoma NF1 4763 neurofibromin 1 17q11.2 1203 7765 613113 "NP_001035957;NP_000258;NP_001121619" "NM_001042492;NM_000267;NM_001128147" "ENSP00000348498;ENSP00000351015;ENSP00000412921" known 0 1 0 Eukaryotes 22 2 Cell cycle,Cell motility and interactions,Cell response to stimuli,Cellular processes,Development,Multicellular activities,Regulation of intracellular processes and metabolism,Signal transduction 86 chr17 29422328 29701170 CGC,HTMS,WES glioma,neurofibroma,breast,glioblastoma,lung,ovarian,pancreas,prostate,sarcoma,bladder,colorectal NF2 4771 neurofibromin 2 (merlin) 22q12.2 6980 7773 607379 "NP_861546;NP_000259;NP_861969;NP_861967;NP_861971;NP_861968;NP_861970;NP_057502;NP_861966" "NM_181825;NM_000268;NM_181831;NM_181829;NM_181833;NM_181830;NM_181832;NM_016418;NM_181827;NM_181834;NM_181835;NM_181826;NM_181828" "ENSP00000344666;ENSP00000384797;ENSP00000354897;ENSP00000335652;ENSP00000409921" known 0 1 0 Eukaryotes 12 4 Cell cycle,Cell motility and interactions,Cell response to stimuli,Cellular metabolism,Cellular processes,DNA/RNA metabolism and transcription,Development,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction 56 chr22 29999988 30090788 CGC,HTMS acoustic neuroma,kidney,meningioma NFE2L2 4780 nuclear factor (erythroid-derived 2)-like 2 2q31 2732 7782 600492 "NP_001138884;NP_001138885;NP_006155" "NM_001145412;NM_001145413;NM_006164" "ENSP00000380253;ENSP00000411575;ENSP00000380252" known 1 0 0 Eukaryotes 50 6 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription 103 chr2 178095516 178129304 CGC,WES head and neck squamous cell carcinoma,lung,liver,pancreas NFE2L3 9603 nuclear factor (erythroid-derived 2)-like 3 7p15.2 9162 7783 604135 NP_004280 NM_004289 ENSP00000056233 candidate 0 0 2 Eukaryotes 4 0 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription 63 chr7 26192119 26225400 WES melanoma NFIB 4781 nuclear factor I/B 9p24.1 9008 7785 600728 "NP_001177666;NP_005587;NP_001177667" "NM_001190737;NM_005596;NM_001190738" "ENSP00000370321;ENSP00000370346" known 1 0 0 Metazoans 8 9 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription 96 chr9 14112998 14307540 CGC adenoid cystic carcinoma,lipoma NFKB2 4791 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) 10q24 1239 7795 164012 "NP_001070961;NP_001070962;NP_002493" "NM_001077493;NM_001077494;NM_002502" "ENSP00000358983;ENSP00000189444" known 1 0 0 Last Universal Common Ancestor 102 2 Cell motility and interactions,Cellular metabolism,DNA/RNA metabolism and transcription,Development,Immune system response,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction 48 chr10 104156004 104162130 CGC non-hodgkin lymphoma NFKBIA 4792 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 14q13 1235 7797 164008 NP_065390 NM_020529 ENSP00000216797 candidate 0 0 0 Last Universal Common Ancestor 60 4 Cell cycle,Cell response to stimuli,Cellular processes,DNA/RNA metabolism and transcription,Development,Regulation of intracellular processes and metabolism,Signal transduction 109 chr14 35871222 35873850 WES lymphoma NGEF 25791 neuronal guanine nucleotide exchange factor 2q37 10442 7807 605991 "NP_001107562;NP_062824" "NM_001114090;NM_019850" "ENSP00000362653;ENSP00000264051" candidate 0 0 0 Eukaryotes 11 0 Development,Signal transduction -1 chr2 233744202 233839600 WES glioblastoma NIN 51199 ninein (GSK3B interacting protein) 14q22.1 9785 14906 608684 "NP_891991;NP_065972;NP_057434;NP_891989" "NM_182946;NM_020921;NM_016350;NM_182944;NM_182945" "ENSP00000371474;ENSP00000245441;ENSP00000412391;ENSP00000371472" known 1 0 0 Metazoans 15 14 Cellular metabolism,Cellular processes,Signal transduction 14 chr14 51190184 51288774 CGC myeloma NIPA2 81614 non imprinted in Prader-Willi/Angelman syndrome 2 15q11.2 16290 17044 608146 "NP_001171817;NP_001008860;NP_112184;NP_001008894;NP_001171818;NP_001008892" "NM_001184888;NM_001008860;NM_030922;NM_001008894;NM_001184889;NM_001008892" "ENSP00000381096;ENSP00000337618" candidate 0 0 1 Eukaryotes 1 0 -1 94 chr15 23006224 23021336 WES,WGS prostate,chronic lymphocytic leukemia NKX2-1 7080 NK2 homeobox 1 14q13 2798 11825 600635 "NP_001073136;NP_003308" "NM_001079668;NM_003317" "ENSP00000346879;ENSP00000429607" known 1 0 0 Eukaryotes 21 2 Cell cycle,Cell motility and interactions,Cellular metabolism,DNA/RNA metabolism and transcription,Development,Regulation of intracellular processes and metabolism,Regulation of transcription 22 chr14 36986486 36989334 CGC,WES,Amplified lung NKX2-8 26257 NK2 homeobox 8 14q13.3 4456 16364 603245 NP_055175 NM_014360 ENSP00000258829 known 0 0 0 Eukaryotes 0 0 Cell cycle,Cellular metabolism,DNA/RNA metabolism and transcription,Development,Regulation of intracellular processes and metabolism,Regulation of transcription 4 chr14 37050110 37051594 CGC,Amplified NLGN1 22871 neuroligin 1 3q26.31 7195 14291 600568 NP_055747 NM_014932 ENSP00000354541 candidate 0 0 3 Last Universal Common Ancestor 6 0 Cell cycle,Cell motility and interactions,Cellular processes,Development,Multicellular activities,Signal transduction 36 chr3 173322389 173999090 WGS lung NLN 57486 neurolysin (metallopeptidase M3 family) 5q12.3 7495 16058 611530 NP_065777 NM_020726 ENSP00000370372 candidate 0 0 0 Last Universal Common Ancestor 5 0 Cellular metabolism -1 chr5 65054386 65118740 WES chronic lymphocytic leukemia NLRP1 22861 NLR family, pyrin domain containing 1 17p13.2 7364 14374 606636 "NP_127499;NP_001028225;NP_127497;NP_127500;NP_055737" "NM_033006;NM_001033053;NM_033004;NM_033007;NM_014922" "ENSP00000262467;ENSP00000324366" candidate 0 0 0 Eukaryotes 17 1 Cell cycle,Development,Regulation of intracellular processes and metabolism,Signal transduction 92 chr17 5418077 5487277 WES liver NLRP3 114548 NLR family, pyrin domain containing 3 1q44 5915 16400 606416 "NP_899632;NP_004886;NP_001120933;NP_001073289;NP_001230062;NP_001120934" "NM_183395;NM_004895;NM_001127461;NM_001079821;NM_001243133;NM_001127462" "ENSP00000375704;ENSP00000355453;ENSP00000337383;ENSP00000294752" candidate 0 0 0 Last Universal Common Ancestor 7 1 Cell cycle,Cell response to stimuli,Cellular metabolism,Cellular processes,DNA/RNA metabolism and transcription,Development,Immune system response,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction 8 chr1 247582097 247611803 HTMS breast,lung,ovarian,pancreas,prostate NLRP8 126205 NLR family, pyrin domain containing 8 19q13.43 14807 22940 609659 NP_789781 NM_176811 ENSP00000291971 candidate 0 0 0 Eukaryotes 0 0 -1 -1 chr19 56459269 56499276 WES medulloblastoma NME9 347736 NME gene family member 9 3q22.3 18250 21343 - NP_835231 NM_178130 ENSP00000372667 candidate 0 0 0 Last Universal Common Ancestor 1 0 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism -1 chr3 138022332 138038427 WGS breast NOD1 10392 nucleotide-binding oligomerization domain containing 1 7p15-p14 5815 16390 605980 NP_006083 NM_006092 ENSP00000222823 candidate 0 0 0 Eukaryotes 8 0 Cell cycle,Cell response to stimuli,Cellular metabolism,Immune system response,Regulation of intracellular processes and metabolism,Signal transduction 56 chr7 30465257 30496537 WGS lymphoma NONO 4841 non-POU domain containing, octamer-binding Xq13.1 2098 7871 300084 "NP_031389;NP_001138882;NP_001138881;NP_001138880" "NM_007363;NM_001145410;NM_001145409;NM_001145408" "ENSP00000362947;ENSP00000441364;ENSP00000276079" known 1 0 1 Vertebrates 126 0 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription 109 chrX 70510488 70519923 CGC kidney NOS3 4846 nitric oxide synthase 3 (endothelial cell) 7q36 1224 7876 163729 "NP_000594;NP_001153581;NP_001153582;NP_001153583" "NM_000603;NM_001160109;NM_001160110;NM_001160111" "ENSP00000297494;ENSP00000420551;ENSP00000420215" candidate 0 0 0 Last Universal Common Ancestor 64 2 Cell cycle,Cellular metabolism,Cellular processes,Development,Multicellular activities,Regulation of intracellular processes and metabolism,Signal transduction 16 chr7 150690892 150711254 WES colorectal NOTCH1 4851 notch 1 9q34.3 1827 7881 190198 NP_060087 NM_017617 ENSP00000277541 known 1 0 0 Last Universal Common Ancestor 78 13 Cell cycle,Cellular metabolism,DNA/RNA metabolism and transcription,Development,Multicellular activities,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction 77 chr9 139390526 139440238 CGC,WES,WGS leukemia,breast,chronic lymphocytic leukemia,head and neck squamous cell carcinoma,lung,lymphoma,oligodendroglioma NOTCH2 4853 notch 2 1p13-p11 2606 7882 600275 "NP_001186930;NP_077719" "NM_001200001;NM_024408" ENSP00000256646 known 1 0 0 Last Universal Common Ancestor 30 12 Cell cycle,Cellular metabolism,DNA/RNA metabolism and transcription,Development,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction 108 chr1 120457932 120612020 CGC lymphoma NOVA1 4857 neuro-oncological ventral antigen 1 14q 3693 7886 602157 "NP_006482;NP_006480;NP_002506" "NM_006491;NM_006489;NM_002515" "ENSP00000438875;ENSP00000447391" candidate 0 0 0 Eukaryotes 5 2 DNA/RNA metabolism and transcription,Multicellular activities,Regulation of transcription 71 chr14 26917168 27066642 WGS liver NOX3 50508 NADPH oxidase 3 6q25.3 6165 7890 607105 NP_056533 NM_015718 ENSP00000159060 candidate 0 0 0 Last Universal Common Ancestor 0 1 Regulation of intracellular processes and metabolism 0 chr6 155717973 155776934 WGS prostate NPHP4 261734 nephronophthisis 4 1p36 6238 19104 607215 NP_055917 NM_015102 ENSP00000367398 candidate 0 0 0 Eukaryotes 6 0 Cell response to stimuli,Cellular processes,Multicellular activities,Signal transduction 58 chr1 5923328 6046349 WGS glioblastoma,prostate NPM1 4869 nucleophosmin (nucleolar phosphoprotein B23, numatrin) 5q35.1 1246 7910 164040 "NP_954654;NP_001032827;NP_002511" "NM_199185;NM_001037738;NM_002520" "ENSP00000296930;ENSP00000341168" known 1 0 31 Metazoans 62 0 Cell cycle,Cellular metabolism,Cellular processes,DNA/RNA metabolism and transcription,Development,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction 109 chr5 93018546 93019423 CGC,WGS leukemia,non-hodgkin lymphoma,acute myeloid leukemia NPSR1 387129 neuropeptide S receptor 1 7p14.3 10547 23631 608595 "NP_997056;NP_997055" "NM_207173;NM_207172" "ENSP00000353788;ENSP00000352839" candidate 0 0 0 Metazoans 0 0 Signal transduction -1 chr7 34698025 34917793 WGS melanoma NPY2R 4887 neuropeptide Y receptor Y2 4q31 1216 7957 162642 NP_000901 NM_000910 ENSP00000332591 candidate 0 0 0 Metazoans 0 0 Signal transduction 59 chr4 156135092 156136234 HTMS breast,lung,ovarian,pancreas,prostate NPY5R 4889 neuropeptide Y receptor Y5 4q31-q32 3591 7958 602001 NP_006165 NM_006174 ENSP00000339377 candidate 0 0 0 Metazoans 5 0 Multicellular activities,Signal transduction 61 chr4 164271426 164272760 HTMS breast,lung,ovarian,pancreas,prostate NR4A3 8013 nuclear receptor subfamily 4, group A, member 3 9q22 2766 7982 600542 "NP_775292;NP_775291;NP_008912" "NM_173200;NM_173198;NM_173199;NM_006981" "ENSP00000340301;ENSP00000333122" known 1 0 0 Metazoans 12 4 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription 55 chr9 102590322 102626146 CGC sarcoma NRAS 4893 neuroblastoma RAS viral (v-ras) oncogene homolog 1p13.2 1273 7989 164790 NP_002515 NM_002524 ENSP00000358548 known 1 0 2 Last Universal Common Ancestor 38 9 Cell cycle,Cell response to stimuli,Cellular processes,Development,Multicellular activities,Regulation of intracellular processes and metabolism,Signal transduction 52 chr1 115251159 115258781 CGC,HTMS,WES,WGS leukemia,melanoma,myeloma,thyroid,lung,colorectal (non-hypermutated),myelodysplasia,acute myeloid leukemia NRG2 9542 neuregulin 2 5q23-q33 4821 7998 603818 "NP_053586;NP_053585;NP_004874;NP_053584;NP_001171864" "NM_013983;NM_013982;NM_013984;NM_004883;NM_013985;NM_013981;NM_001184935" ENSP00000444235 candidate 0 0 0 Eukaryotes 2 0 Signal transduction 24 chr5 139227505 139422654 WES pancreas NRG3 10718 neuregulin 3 10q22-q23 16115 7999 605533 "NP_001010848;NP_001159445;NP_001159444" "NM_001010848;NM_001165973;NM_001165972" ENSP00000361215 candidate 0 0 0 Metazoans 1 0 Cell cycle,Development,Regulation of intracellular processes and metabolism,Signal transduction -1 chr10 83635097 84745358 HTMS breast,lung,ovarian,pancreas,prostate NRK 203447 Nik related kinase Xq22.3 14841 25391 300791 NP_940867 NM_198465 ENSP00000434830 candidate 0 0 0 Last Universal Common Ancestor 1 1 Cellular metabolism,Cellular processes,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription -1 chrX 105066839 105199589 WES,WGS head and neck squamous cell carcinoma,breast NRXN2 9379 neurexin 2 11q13 11859 8009 600566 "NP_055895;NP_620060;NP_620063" "NM_015080;NM_138732;NM_138734" "ENSP00000265459;ENSP00000366782;ENSP00000301894" candidate 0 0 0 Metazoans 11 0 Cellular processes,Development,Multicellular activities,Signal transduction 38 chr11 64374671 64481171 WES head and neck squamous cell carcinoma NRXN3 9369 neurexin 3 14q31 8989 8010 600567 "NP_620426;NP_001098720;NP_004787" "NM_138970;NM_001105250;NM_004796" "ENSP00000394426;ENSP00000281127" candidate 0 0 1 Metazoans 7 1 Cell cycle,Cell motility and interactions,Development 21 chr14 79117568 80328304 WES head and neck squamous cell carcinoma NSD1 64324 nuclear receptor binding SET domain protein 1 5q35 9455 14234 606681 "NP_071900;NP_758859" "NM_022455;NM_172349" "ENSP00000395929;ENSP00000346111" known 1 0 0 Last Universal Common Ancestor 14 0 Cellular metabolism,Cellular processes,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription 46 chr5 176562105 176722457 CGC,WES leukemia,head and neck squamous cell carcinoma NT5DC2 64943 5'-nucleotidase domain containing 2 3p21.1 7770 25717 - "NP_001127703;NP_075059" "NM_001134231;NM_022908" "ENSP00000406933;ENSP00000302468" candidate 0 0 0 Eukaryotes 8 1 -1 52 chr3 52558489 52567753 WGS lymphoma NTNG1 22854 netrin G1 1p13.3 16389 23319 608818 "NP_001106697;NP_001106699;NP_055732" "NM_001113226;NM_001113228;NM_014917" "ENSP00000359090;ENSP00000359088;ENSP00000359091" candidate 0 0 0 Metazoans 3 1 Cell cycle,Development 54 chr1 107691216 108023459 WES colorectal NTRK1 4914 neurotrophic tyrosine kinase, receptor, type 1 1q21-q22 1869 8031 191315 "NP_001012331;NP_001007793;NP_002520" "NM_001012331;NM_001007792;NM_002529" "ENSP00000376120;ENSP00000357179;ENSP00000431418" known 1 0 0 Last Universal Common Ancestor 60 0 Cellular metabolism,Cellular processes,Development,Regulation of intracellular processes and metabolism,Signal transduction 0 chr1 156830727 156851431 CGC,HTMS thyroid,lung,sarcoma NTRK2 4915 neurotrophic tyrosine kinase, receptor, type 2 9q22.1 2712 8032 600456 "NP_001007098;NP_006171;NP_001018074;NP_001018076;NP_001018075" "NM_001007097;NM_006180;NM_001018064;NM_001018066;NM_001018065" "ENSP00000379221;ENSP00000365386;ENSP00000306167;ENSP00000365381;ENSP00000365387" candidate 0 0 0 Last Universal Common Ancestor 21 1 Cellular metabolism,Cellular processes,Development,Regulation of intracellular processes and metabolism,Signal transduction 94 chr9 87285664 87636349 WGS liver NTRK3 4916 neurotrophic tyrosine kinase, receptor, type 3 15q25 1870 8033 191316 "NP_001230030;NP_002521;NP_001007157;NP_001012338" "NM_001243101;NM_002530;NM_001007156;NM_001012338" "ENSP00000318328;ENSP00000354207;ENSP00000453959;ENSP00000347397" known 1 0 0 Last Universal Common Ancestor 4 18 Cellular metabolism,Cellular processes,Development,Signal transduction 97 chr15 88420169 88799384 CGC,HTMS breast,sarcoma,lung NUDT11 55190 nudix (nucleoside diphosphate linked moiety X)-type motif 11 Xp11.22 6667 18011 300528 NP_060629 NM_018159 ENSP00000365160 candidate 0 0 4 Eukaryotes 2 0 -1 32 chrX 51238805 51239296 WES head and neck squamous cell carcinoma NUDT14 256281 nudix (nucleoside diphosphate linked moiety X)-type motif 14 14q32.33 14847 20141 609219 NP_803877 NM_177533 ENSP00000376349 candidate 0 0 0 Last Universal Common Ancestor 6 0 -1 -1 chr14 105639361 105647546 WES head and neck squamous cell carcinoma NUMA1 4926 nuclear mitotic apparatus protein 1 11q13 1236 8059 164009 NP_006176 NM_006185 ENSP00000377298 known 1 0 0 Last Universal Common Ancestor 10 1 Cell cycle,Cellular processes 83 chr11 71714933 71746989 CGC,WGS leukemia,lung NUP133 55746 nucleoporin 133kDa 1q42.13 6354 18016 607613 NP_060700 NM_018230 ENSP00000261396 candidate 0 0 0 Eukaryotes 27 0 Cellular processes,DNA/RNA metabolism and transcription 88 chr1 229577654 229643996 WES breast NUP210 23225 nucleoporin 210kDa 3p25.1 6368 30052 607703 NP_079199 NM_024923 ENSP00000254508 candidate 0 0 0 Eukaryotes 18 3 Cellular processes,DNA/RNA metabolism and transcription 91 chr3 13359184 13461726 WES colorectal NUP214 8021 nucleoporin 214kDa 9q34.1 258 8064 114350 NP_005076 NM_005085 ENSP00000352400 known 1 0 0 Last Universal Common Ancestor 54 1 Cellular processes,DNA/RNA metabolism and transcription 82 chr9 134001092 134106158 CGC,WES leukemia,breast NUP98 4928 nucleoporin 98kDa 11p15.5 3012 8068 601021 "NP_005378;NP_624358;NP_624357;NP_057404" "NM_005387;NM_139132;NM_139131;NM_016320" "ENSP00000380202;ENSP00000316032;ENSP00000380199;ENSP00000347404" known 1 0 0 Last Universal Common Ancestor 12 2 Cellular metabolism,Cellular processes,DNA/RNA metabolism and transcription 74 chr11 3697392 3803347 CGC leukemia NXF1 10482 nuclear RNA export factor 1 11q12-q13 4035 8071 602647 "NP_006353;NP_001074960" "NM_006362;NM_001081491" "ENSP00000453885;ENSP00000294172" candidate 0 0 0 Eukaryotes 126 0 Cellular processes,DNA/RNA metabolism and transcription 106 chr11 62560113 62571451 WES chronic lymphocytic leukemia NXPH2 11249 neurexophilin 2 2q22.1 11983 8076 604635 NP_009157 NM_007226 - candidate 0 0 0 Vertebrates 4 2 Signal transduction -1 chr2 139428495 139537811 WGS melanoma OBSCN 84033 obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF 1q42.13 10551 15719 608616 "NP_443075;NP_001092093" "NM_052843;NM_001098623" "ENSP00000409493;ENSP00000455507;ENSP00000284548" candidate 0 0 0 Last Universal Common Ancestor 17 1 Cellular metabolism,Cellular processes,Signal transduction 2 chr1 228399485 228566493 WGS melanoma OC90 729330 otoconin 90 8q24.22 - 8100 601658 NP_001073868 NM_001080399 ENSP00000254627 candidate 0 0 0 Vertebrates 2 0 Cellular metabolism -1 chr8 133036731 133067273 WGS melanoma OFD1 8481 oral-facial-digital syndrome 1 Xp22 2162 2567 300170 NP_003602 NM_003611 ENSP00000344314 candidate 0 0 1 Eukaryotes 9 1 -1 90 chrX 13753367 13787224 WES lymphoma OGN 4969 osteoglycin 9q22 3856 8126 602383 "NP_148935;NP_054776" "NM_024416;NM_033014;NM_014057" "ENSP00000364711;ENSP00000262551" candidate 0 0 0 Eukaryotes 3 0 -1 15 chr9 95147905 95165689 WGS prostate OLIG2 10215 oligodendrocyte lineage transcription factor 2 21q22.11 7334 9398 606386 NP_005797 NM_005806 ENSP00000371794 known 1 0 0 Metazoans 5 2 Cell cycle,Cellular metabolism,DNA/RNA metabolism and transcription,Development,Multicellular activities,Regulation of intracellular processes and metabolism,Regulation of transcription 50 chr21 34399171 34400139 CGC leukemia OMD 4958 osteomodulin 9q22.31 10128 8134 - NP_005005 NM_005014 ENSP00000364700 known 1 0 0 Last Universal Common Ancestor 0 0 -1 41 chr9 95177437 95179840 CGC bone cyst OR10AG1 282770 olfactory receptor, family 10, subfamily AG, member 1 11q11 14885 19607 - NP_001005491 NM_001005491 ENSP00000311477 candidate 0 0 0 Mammals 0 0 Cell response to stimuli,Signal transduction -1 chr11 55735037 55735939 WES melanoma OR10G7 390265 olfactory receptor, family 10, subfamily G, member 7 11q24.2 14890 14842 - NP_001004463 NM_001004463 ENSP00000329689 candidate 0 0 4 Mammals 0 0 Cell response to stimuli,Signal transduction -1 chr11 123908776 123909708 WES lung OR10G9 219870 olfactory receptor, family 10, subfamily G, member 9 11q24.1 17666 15129 - NP_001001953 NM_001001953 ENSP00000364164 candidate 0 0 3 Mammals 0 0 Cell response to stimuli,Signal transduction -1 chr11 123893720 123894652 WES melanoma OR10R2 343406 olfactory receptor, family 10, subfamily R, member 2 1q23.1 17674 14820 - NP_001004472 NM_001004472 ENSP00000357134 candidate 0 0 1 Mammals 0 0 Signal transduction -1 chr1 158449668 158450672 WES pancreas OR11L1 391189 olfactory receptor, family 11, subfamily L, member 1 1q44 17677 14998 - NP_001001959 NM_001001959 ENSP00000348033 candidate 0 0 0 Metazoans 0 0 Cell response to stimuli,Signal transduction -1 chr1 248004233 248005198 WES lung OR1J2 26740 olfactory receptor, family 1, subfamily J, member 2 9q34.11 14917 8209 - NP_473448 NM_054107 ENSP00000335575 candidate 0 0 2 Mammals 4 1 Cell response to stimuli,Signal transduction -1 chr9 125273081 125274019 WGS melanoma OR1L8 138881 olfactory receptor, family 1, subfamily L, member 8 9q33.2 14923 15110 - NP_001004454 NM_001004454 ENSP00000306607 candidate 0 0 4 Metazoans 0 0 Cell response to stimuli,Signal transduction -1 chr9 125329830 125330756 WGS chronic lymphocytic leukemia OR1M1 125963 olfactory receptor, family 1, subfamily M, member 1 19p13.2 17689 8220 - NP_001004456 NM_001004456 ENSP00000401966 candidate 0 0 0 Mammals 4 0 Cell response to stimuli,Signal transduction -1 chr19 9203921 9204859 WES melanoma OR2A2 442361 olfactory receptor, family 2, subfamily A, member 2 7q35 14931 8230 - NP_001005480 NM_001005480 ENSP00000386209 candidate 0 0 8 Mammals 0 0 Cell response to stimuli,Signal transduction -1 chr7 143806676 143807629 WES melanoma OR2A42 402317 olfactory receptor, family 2, subfamily A, member 42 7q35 18486 31230 - NP_001001802 NM_001001802 ENSP00000375334 candidate 0 0 10 Vertebrates 0 0 Cell response to stimuli,Cellular metabolism,Signal transduction -1 chr7 144015218 144016147 WES melanoma OR2L13 284521 olfactory receptor, family 2, subfamily L, member 13 1q44 17702 19578 - NP_787107 NM_175911 ENSP00000355434 candidate 0 0 6 Mammals 1 0 Cell response to stimuli,Signal transduction -1 chr1 248262678 248263613 WES glioblastoma OR2M4 26245 olfactory receptor, family 2, subfamily M, member 4 1q44 14946 8270 - NP_059974 NM_017504 ENSP00000306688 candidate 0 0 5 Eukaryotes 0 0 Cell response to stimuli,Signal transduction -1 chr1 248402231 248403163 WES chronic lymphocytic leukemia OR2T11 127077 olfactory receptor, family 2, subfamily T, member 11 1q44 17705 19574 - NP_001001964 NM_001001964 ENSP00000328934 candidate 0 0 5 Mammals 0 0 Cell response to stimuli,Signal transduction -1 chr1 248789482 248790429 WGS lung OR2T33 391195 olfactory receptor, family 2, subfamily T, member 33 1q44 14953 31255 - NP_001004695 NM_001004695 ENSP00000324687 candidate 0 0 3 Mammals 0 0 Cell response to stimuli,Signal transduction -1 chr1 248436157 248437116 WGS melanoma OR2T34 127068 olfactory receptor, family 2, subfamily T, member 34 1q44 14954 31256 - NP_001001821 NM_001001821 ENSP00000330904 candidate 0 0 4 Vertebrates 0 0 Cell response to stimuli,Signal transduction -1 chr1 248737105 248738058 WGS lymphoma OR4C13 283092 olfactory receptor, family 4, subfamily C, member 13 11p11.12 17720 15169 - NP_001001955 NM_001001955 ENSP00000452277 candidate 0 0 12 Mammals 0 0 Cell response to stimuli,Signal transduction -1 chr11 49973975 49974901 WES melanoma OR4C15 81309 olfactory receptor, family 4, subfamily C, member 15 11q11 14963 15171 - NP_001001920 NM_001001920 ENSP00000324958 candidate 0 0 0 Mammals 0 0 Cell response to stimuli,Signal transduction -1 chr11 55321783 55322892 WES gastric,head and neck squamous cell carcinoma OR4C46 119749 olfactory receptor, family 4, subfamily C, member 46 11p11.12 14964 31271 614273 NP_001004703 NM_001004703 ENSP00000329056 candidate 0 0 12 Mammals 0 0 Cell response to stimuli,Signal transduction -1 chr11 51515282 51516208 WES gastric OR4C6 219432 olfactory receptor, family 4, subfamily C, member 6 11q11 17724 14743 - NP_001004704 NM_001004704 ENSP00000324769 candidate 0 0 9 Mammals 0 0 Cell response to stimuli,Signal transduction -1 chr11 55432643 55433569 WES melanoma OR4D11 219986 olfactory receptor, family 4, subfamily D, member 11 11q12.1 17725 15174 - NP_001004706 NM_001004706 ENSP00000320077 candidate 0 0 4 Mammals 0 0 Cell response to stimuli,Signal transduction -1 chr11 59271049 59271981 WGS melanoma OR4K1 79544 olfactory receptor, family 4, subfamily K, member 1 14q11.2 14975 14726 - NP_001004063 NM_001004063 ENSP00000285600 candidate 0 0 5 Mammals 0 0 Cell response to stimuli,Signal transduction -1 chr14 20403826 20404758 WES melanoma OR4K14 122740 olfactory receptor, family 4, subfamily K, member 14 14q11.2 14977 15352 - NP_001004712 NM_001004712 ENSP00000305011 candidate 0 0 0 Mammals 0 0 Cell response to stimuli,Signal transduction -1 chr14 20482423 20483352 WES melanoma OR4L1 122742 olfactory receptor, family 4, subfamily L, member 1 14q11.2 14982 15356 - NP_001004717 NM_001004717 ENSP00000319217 candidate 0 0 0 Mammals 0 0 Cell response to stimuli,Signal transduction -1 chr14 20528204 20529139 WES pancreas OR4N5 390437 olfactory receptor, family 4, subfamily N, member 5 14q11.2 14985 15358 - NP_001004724 NM_001004724 ENSP00000332110 candidate 0 0 5 Mammals 0 0 Cell response to stimuli,Signal transduction -1 chr14 20611895 20612818 WGS glioblastoma OR4Q3 441669 olfactory receptor, family 4, subfamily Q, member 3 14q11.2 17732 15426 - NP_751944 NM_172194 ENSP00000330049 candidate 0 0 1 Vertebrates 0 0 Cell response to stimuli,Signal transduction -1 chr14 20215587 20216525 WGS breast OR4S2 219431 olfactory receptor, family 4, subfamily S, member 2 11q11 14988 15183 - NP_001004059 NM_001004059 ENSP00000310337 candidate 0 0 1 Vertebrates 3 0 Cell response to stimuli,Signal transduction -1 chr11 55418380 55419312 WGS melanoma OR51E1 143503 olfactory receptor, family 51, subfamily E, member 1 11p15.4 14996 15194 611267 NP_689643 NM_152430 ENSP00000380155 candidate 0 0 0 Vertebrates 0 0 Cell response to stimuli,Signal transduction -1 chr11 4673757 4674710 WES colorectal OR51I2 390064 olfactory receptor, family 51, subfamily I, member 2 11p15.4 15000 15201 - NP_001004754 NM_001004754 ENSP00000341987 candidate 0 0 1 Vertebrates 0 0 Cell response to stimuli,Signal transduction -1 chr11 5474719 5475654 WES melanoma OR52A5 390054 olfactory receptor, family 52, subfamily A, member 5 11p15.4 15005 19580 - NP_001005160 NM_001005160 ENSP00000303469 candidate 0 0 2 Metazoans 0 0 Cell response to stimuli,Signal transduction -1 chr11 5152925 5153872 WGS lung OR52E8 390079 olfactory receptor, family 52, subfamily E, member 8 11p15.4 15013 15217 - NP_001005168 NM_001005168 ENSP00000444054 candidate 0 0 6 Metazoans 0 0 Cell response to stimuli,Signal transduction -1 chr11 5877982 5878932 WES melanoma OR5B17 219965 olfactory receptor, family 5, subfamily B, member 17 11q12.1 15036 15267 - NP_001005489 NM_001005489 ENSP00000349945 candidate 0 0 5 Mammals 0 0 Cell response to stimuli,Signal transduction -1 chr11 58125601 58126542 WES lung OR5H2 79310 olfactory receptor, family 5, subfamily H, member 2 3q12.1 15042 14752 - NP_001005482 NM_001005482 ENSP00000347418 candidate 0 0 9 Mammals 0 0 Signal transduction -1 chr3 98001732 98002673 WGS melanoma OR5L1 219437 olfactory receptor, family 5, subfamily L, member 1 11q11 15045 8350 - NP_001004738 NM_001004738 ENSP00000335529 candidate 0 0 2 Metazoans 150 0 Cell response to stimuli,Signal transduction -1 chr11 55578943 55579875 WES melanoma,prostate OR5L2 26338 olfactory receptor, family 5, subfamily L, member 2 11q11 15046 8351 - NP_001004739 NM_001004739 ENSP00000367650 candidate 0 0 1 Metazoans 3 0 Cell response to stimuli,Signal transduction -1 chr11 55594695 55595627 WES head and neck squamous cell carcinoma OR5M5P 390166 olfactory receptor, family 5, subfamily M, member 5 pseudogene 11q12.1 - 14810 - - - - candidate 0 0 -1 Mammals 0 0 -1 -1 - 0 0 WGS lung OR6A2 8590 olfactory receptor, family 6, subfamily A, member 2 11p15 9771 15301 608495 NP_003687 NM_003696 ENSP00000330384 candidate 0 0 0 Mammals 0 0 Cell response to stimuli,Signal transduction 38 chr11 6815959 6816939 WES breast OR6K3 391114 olfactory receptor, family 6, subfamily K, member 3 1q23.1 15064 15030 - NP_001005327 NM_001005327 ENSP00000357127 candidate 0 0 2 Metazoans 0 0 Signal transduction -1 chr1 158686961 158687905 WES lymphoma OR8H2 390151 olfactory receptor, family 8, subfamily H, member 2 11q12.1 15083 15308 - NP_001005200 NM_001005200 ENSP00000323982 candidate 0 0 2 Vertebrates 0 0 Cell response to stimuli,Signal transduction -1 chr11 55872519 55873454 WES head and neck squamous cell carcinoma OR8K1 390157 olfactory receptor, family 8, subfamily K, member 1 11q12.1 15086 14831 - NP_001002907 NM_001002907 ENSP00000279783 candidate 0 0 3 Mammals 0 0 Cell response to stimuli,Signal transduction -1 chr11 56113515 56114471 WES head and neck squamous cell carcinoma ORC1 4998 origin recognition complex, subunit 1 1p32 3544 8487 601902 "NP_001177748;NP_004144;NP_001177747" "NM_001190819;NM_004153;NM_001190818" "ENSP00000360621;ENSP00000360623" candidate 0 0 0 Last Universal Common Ancestor 20 2 Cellular metabolism,DNA/RNA metabolism and transcription 14 chr1 52838856 52867895 WGS prostate OTOF 9381 otoferlin 2p23.1 4727 8515 603681 "NP_004793;NP_919304;NP_919224;NP_919303" "NM_004802;NM_194323;NM_194248;NM_194322" "ENSP00000345137;ENSP00000272371;ENSP00000383906;ENSP00000344521" candidate 0 0 0 Eukaryotes 2 0 Cell response to stimuli,Cellular processes 0 chr2 26682896 26781439 WES breast OTOGL 283310 otogelin-like 12q21.31 8815 26901 - NP_775862 NM_173591 ENSP00000400895 candidate 0 0 0 - 0 1 Cellular metabolism -1 chr12 80603239 80771825 WES chronic lymphocytic leukemia OTOP1 133060 otopetrin 1 4p16.3 7421 19656 607806 NP_819056 NM_177998 ENSP00000296358 candidate 0 0 1 Vertebrates 0 0 Development -1 chr4 4190533 4228591 WGS liver OVCH1 341350 ovochymase 1 12p11.22 7138 23080 - NP_899234 NM_183378 ENSP00000326708 candidate 0 0 0 Last Universal Common Ancestor 1 0 Cellular metabolism -1 chr12 29586684 29650619 WES pancreas OXA1L 5018 oxidase (cytochrome c) assembly 1-like 14q11.2 3043 8526 601066 NP_005006 NM_005015 ENSP00000285848 candidate 0 0 0 Last Universal Common Ancestor 18 3 Cellular metabolism,Cellular processes 97 chr14 23235731 23240764 WGS glioblastoma P2RX7 5027 purinergic receptor P2X, ligand-gated ion channel, 7 12q24 3977 8537 602566 NP_002553 "NR_033952;NM_177427;NR_033951;NR_033953;NR_033949;NR_033950;NR_033955;NR_033948;NR_033956;NM_002562;NR_033954" - candidate 0 0 0 Metazoans 10 2 Cell cycle,Cell response to stimuli,Cellular metabolism,Cellular processes,Development,Multicellular activities,Other,Regulation of intracellular processes and metabolism,Signal transduction 29 chr12 121570774 121622602 WES colorectal P2RY6 5031 pyrimidinergic receptor P2Y, G-protein coupled, 6 11q13.5 3906 8543 602451 "NP_789767;NP_004145;NP_789768;NP_789766" "NM_176797;NM_004154;NM_176798;NM_176796" "ENSP00000377215;ENSP00000309771;ENSP00000377217;ENSP00000377216" candidate 0 0 0 Vertebrates 0 1 Cellular processes,Signal transduction 48 chr11 73007564 73008547 WES acute myeloid leukemia P2RY8 286530 purinergic receptor P2Y, G-protein coupled, 8 "Xp22.33; Yp11.3" 6671 15524 300525 NP_835230 NM_178129 ENSP00000370697 known 1 0 1 Vertebrates 1 0 Signal transduction -1 chrX 1584375 1585451 CGC,HTMS,WES leukemia,breast,lung,ovarian,pancreas,prostate,lymphoma PABPC1 26986 poly(A) binding protein, cytoplasmic 1 8q22.2-q23 5247 8554 604679 NP_002559 NM_002568 ENSP00000313007 candidate 0 0 4 Last Universal Common Ancestor 155 3 DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription 109 chr8 101716529 101733811 WES lymphoma PABPC3 5042 poly(A) binding protein, cytoplasmic 3 13q12-q13 5248 8556 604680 NP_112241 NM_030979 - candidate 0 0 2 Last Universal Common Ancestor 8 0 DNA/RNA metabolism and transcription,Regulation of transcription 109 chr13 25670337 25672229 WGS lymphoma PAFAH1B2 5049 platelet-activating factor acetylhydrolase 1b, catalytic subunit 2 (30kDa) 11q23 3940 8575 602508 "NP_002563;NP_001171677;NP_001171676;NP_001171675" "NM_002572;NM_001184748;NM_001184747;NM_001184746" "ENSP00000434951;ENSP00000388742;ENSP00000435289" known 1 0 2 Last Universal Common Ancestor 31 3 Cellular metabolism,Development,Multicellular activities 43 chr11 117023164 117038412 CGC lymphoma PAK1 5058 p21 protein (Cdc42/Rac)-activated kinase 1 11q13-q14 3995 8590 602590 "NP_002567;NP_001122092" "NM_002576;NM_001128620" ENSP00000348696 known 0 0 0 Last Universal Common Ancestor 113 6 Cell cycle,Cellular metabolism,Cellular processes,Regulation of intracellular processes and metabolism,Signal transduction 10 chr11 77034347 77103565 CGC,Amplified PAK3 5063 p21 protein (Cdc42/Rac)-activated kinase 3 Xq23 2142 8592 300142 "NP_001121639;NP_002569;NP_001121644;NP_001121640;NP_001121645;NP_001121638" "NM_001128167;NM_002578;NM_001128172;NM_001128168;NM_001128173;NM_001128166" "ENSP00000410853;ENSP00000401982;ENSP00000353864;ENSP00000389172;ENSP00000262836;ENSP00000361077" candidate 0 0 0 Last Universal Common Ancestor 19 1 Cellular metabolism,Cellular processes 60 chrX 110366332 110463672 HTMS lung PALB2 79728 partner and localizer of BRCA2 16p12.2 7966 26144 610355 NP_078951 NM_024675 ENSP00000261584 known 0 1 0 Metazoans 14 0 -1 7 chr16 23614783 23652478 CGC,WGS breast PAPPA2 60676 pappalysin 2 1q23-q25 10156 14615 - "NP_068755;NP_064714" "NM_021936;NM_020318" ENSP00000356633 candidate 0 0 0 Last Universal Common Ancestor 11 0 Cell cycle,Cellular metabolism,Regulation of intracellular processes and metabolism 82 chr1 176525459 176811587 WGS lung PAQR7 164091 progestin and adipoQ receptor family member VII 1p36.11 9692 23146 607779 NP_848509 NM_178422 ENSP00000363414 candidate 0 0 0 Last Universal Common Ancestor 2 0 -1 -1 chr1 26189293 26190330 WGS breast PARP9 83666 poly (ADP-ribose) polymerase family, member 9 3q21 10686 24118 612065 "NP_113646;NP_001139576;NP_001139575;NP_001139577;NP_001139574;NP_001139578" "NM_031458;NM_001146104;NM_001146103;NM_001146105;NM_001146102;NM_001146106" "ENSP00000419506;ENSP00000419001;ENSP00000418894;ENSP00000353512" candidate 0 0 0 Last Universal Common Ancestor 5 4 Cell motility and interactions -1 chr3 122247214 122277323 HTMS breast,lung,ovarian,pancreas,prostate PARVA 55742 parvin, alpha 11p15.3 16283 14652 608120 NP_060692 NM_018222 - candidate 0 0 0 Metazoans 15 2 -1 75 chr11 12399075 12549469 WGS breast PASD1 139135 PAS domain containing 1 Xq28 6613 20686 - NP_775764 NM_173493 ENSP00000359382 candidate 0 0 0 Eukaryotes 0 0 Signal transduction -1 chrX 150773117 150844612 WES lymphoma PATZ1 23598 POZ (BTB) and AT hook containing zinc finger 1 22q12.2 5522 13071 605165 "NP_114441;NP_114439;NP_114440;NP_055138" "NM_032052;NM_032050;NM_032051;NM_014323" "ENSP00000266269;ENSP00000337520;ENSP00000215919;ENSP00000384173" known 1 0 0 Last Universal Common Ancestor 0 0 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription 97 chr22 31722880 31741588 CGC,WGS sarcoma,lung PAX3 5077 paired box 3 2q35-q37|2q35 9421 8617 606597 "NP_852125;NP_852123;NP_852124;NP_000429;NP_039230;NP_001120838;NP_852122;NP_852126" "NM_181460;NM_181458;NM_181459;NM_000438;NM_013942;NM_001127366;NM_181457;NM_181461" "ENSP00000386817;ENSP00000258387;ENSP00000386750;ENSP00000343052;ENSP00000375921;ENSP00000342092" known 1 0 0 Opisthokonts 27 5 Cell cycle,Cell response to stimuli,Cellular metabolism,DNA/RNA metabolism and transcription,Development,Regulation of intracellular processes and metabolism,Regulation of transcription 27 chr2 223065896 223163334 CGC sarcoma PAX5 5079 paired box 5 9p13 1334 8619 167414 NP_057953 NM_016734 - known 1 0 0 Metazoans 16 0 Cellular metabolism,DNA/RNA metabolism and transcription,Development,Multicellular activities,Regulation of intracellular processes and metabolism,Regulation of transcription 11 chr9 36840560 37034028 CGC,HTMS leukemia,non-hodgkin lymphoma,breast,lung,ovarian,pancreas,prostate PAX7 5081 paired box 7 1p36.13 1331 8621 167410 "NP_001128726;NP_002575;NP_039236" "NM_001135254;NM_002584;NM_013945" "ENSP00000403389;ENSP00000364524" known 1 0 0 Opisthokonts 11 1 Cell cycle,Cellular metabolism,DNA/RNA metabolism and transcription,Development,Regulation of intracellular processes and metabolism,Regulation of transcription 8 chr1 18958098 19062530 CGC sarcoma PAX8 7849 paired box 8 2q13 1335 8622 167415 "NP_039247;NP_039246;NP_003457;NP_054698" "NM_013953;NM_013951;NM_013952;NM_003466;NM_013992" "ENSP00000395498;ENSP00000314750;ENSP00000263335;ENSP00000380768" known 1 0 0 Metazoans 19 0 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription 109 chr2 113976113 114004497 CGC thyroid PAX9 5083 paired box 9 14q13.3 1336 8623 167416 NP_006185 NM_006194 ENSP00000384817 known 0 0 0 Metazoans 11 0 Cellular metabolism,DNA/RNA metabolism and transcription,Development,Regulation of intracellular processes and metabolism,Regulation of transcription 42 chr14 37132101 37145654 CGC,Amplified PBRM1 55193 polybromo 1 3p21 - 30064 606083 "NP_060635;NP_851385;NP_060783" "NM_181041;NM_018165;NM_181042;NM_018313" ENSP00000349213 known 0 1 0 Eukaryotes 35 4 Cell cycle,Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription 98 chr3 52582082 52713727 CGC,WES,WGS breast,kidney,pancreas,prostate PBX1 5087 pre-B-cell leukemia homeobox 1 1q23 8889 8632 176310 "NP_001191890;NP_002576;NP_001191892" "NM_001204961;NM_002585;NM_001204963" ENSP00000405890 known 1 0 2 Eukaryotes 33 4 Cellular metabolism,DNA/RNA metabolism and transcription,Development,Regulation of intracellular processes and metabolism,Regulation of transcription 94 chr1 164529060 164815910 CGC leukemia,myoepithelioma PCDH11X 27328 protocadherin 11 X-linked Xq21.3 2215 8656 300246 "NP_055337;NP_116751;NP_001161834;NP_001161832;NP_116749;NP_116750;NP_001161833;NP_001161835" "NM_014522;NM_032969;NM_001168362;NM_001168360;NM_032967;NM_032968;NM_001168361;NM_001168363" "ENSP00000355040;ENSP00000378746;ENSP00000362186;ENSP00000362189" candidate 0 0 1 Eukaryotes 1 0 Cell motility and interactions 32 chrX 91090504 91873936 WES chronic lymphocytic leukemia,colorectal PCDH15 65217 protocadherin-related 15 10q21.1 5698 14674 605514 "NP_001136244;NP_001136242;NP_001136235;NP_001136236;NP_149045;NP_001136243;NP_001136241;NP_001136245;NP_001136240;NP_001136238;NP_001136237;NP_001136239" "NM_001142772;NM_001142770;NM_001142763;NM_001142764;NM_033056;NM_001142771;NM_001142769;NM_001142773;NM_001142768;NM_001142766;NM_001142765;NM_001142767" "ENSP00000354950;ENSP00000412628;ENSP00000378818;ENSP00000378820;ENSP00000378832;ENSP00000378826;ENSP00000363076;ENSP00000378821;ENSP00000322604" candidate 0 0 0 Eukaryotes 0 0 Cell motility and interactions,Cell response to stimuli,Multicellular activities,Regulation of intracellular processes and metabolism -1 chr10 55581621 56424022 WES,WGS head and neck squamous cell carcinoma,pancreas,prostate PCDH17 27253 protocadherin 17 13q21.1 - 14267 611760 NP_001035519 "NM_014459;NM_001040429" ENSP00000367151 candidate 0 0 0 Eukaryotes 4 0 Cell motility and interactions 83 chr13 58206681 58299425 WES pancreas PCDH18 54510 protocadherin 18 4q31 12205 14268 608287 NP_061908 NM_019035 ENSP00000355082 candidate 0 0 0 Eukaryotes 2 0 Cell motility and interactions,Development -1 chr4 138442186 138453242 WES,WGS pancreas,lymphoma PCDH20 64881 protocadherin 20 13q21 - 14257 614449 NP_073754 NM_022843 ENSP00000387250 candidate 0 0 0 Eukaryotes 1 0 Cell motility and interactions -1 chr13 61985379 61989291 WGS glioblastoma PCDH7 5099 protocadherin 7 4p15 4288 8659 602988 "NP_002580;NP_115832;NP_001166994;NP_115833" "NM_002589;NM_032456;NM_001173523;NM_032457" ENSP00000355243 candidate 0 0 0 Eukaryotes 6 3 Cell motility and interactions 73 chr4 30723045 31144468 WGS liver PCDHA13 56136 protocadherin alpha 13 5q31 7554 8667 606319 "NP_114071;NP_061727" "NM_031865;NM_018904" ENSP00000289272 candidate 0 0 6 Eukaryotes 41 0 Cell motility and interactions 17 chr5 140261854 140389519 WES,WGS cholangiocarcinoma,liver PCDHA2 56146 protocadherin alpha 2 5q31 7320 8668 606308 "NP_061728;NP_113683" "NM_031496;NM_018905;NM_031495" "ENSP00000431748;ENSP00000367372" candidate 0 0 -1 Eukaryotes 18 0 Cell motility and interactions,Development 27 - 0 0 WGS lymphoma PCDHA4 56144 protocadherin alpha 4 5q31 7322 8670 606310 "NP_113688;NP_061730" "NM_031500;NM_018907" "ENSP00000435300;ENSP00000349344" candidate 0 0 -1 Eukaryotes 26 2 Cell motility and interactions,Development 17 - 0 0 WGS lymphoma PCDHA6 56142 protocadherin alpha 6 5q31 7324 8672 606312 "NP_114037;NP_114036;NP_061732" "NM_031849;NM_031848;NM_018909" ENSP00000433378 candidate 0 0 9 Eukaryotes 9 1 Cell motility and interactions,Development 25 chr5 140207677 140389519 WGS acute myeloid leukemia PCDHA9 9752 protocadherin alpha 9 5q31 7327 8675 606315 "NP_054724;NP_114063" "NM_014005;NM_031857" "ENSP00000367362;ENSP00000436042" candidate 0 0 7 Eukaryotes 7 0 Cell motility and interactions 55 chr5 140228081 140389519 WES colorectal PCDHB15 56121 protocadherin beta 15 5q31 6959 8686 606341 NP_061758 NM_018935 ENSP00000231173 candidate 0 0 13 Eukaryotes 0 1 Cell motility and interactions,Development -1 chr5 140625147 140627507 WES breast PCDHB6 56130 protocadherin beta 6 5q31 7561 8691 606332 NP_061762 NM_018939 ENSP00000231136 candidate 0 0 13 Eukaryotes 0 0 Cell motility and interactions,Development,Multicellular activities 27 chr5 140529839 140532220 WES lymphoma PCDHB8 56128 protocadherin beta 8 5q31 7563 8693 606334 NP_061993 NM_019120 ENSP00000239444 candidate 0 0 10 Eukaryotes 3 3 Cell motility and interactions 9 chr5 140557616 140560018 WES melanoma PCDHGC5 56097 protocadherin gamma subfamily C, 5 5q31 7318 8718 606306 "NP_061752;NP_115783" "NM_018929;NM_032407" ENSP00000252087 candidate 0 0 0 Eukaryotes 8 1 Cell motility and interactions 36 chr5 140868808 140890737 WES chronic lymphocytic leukemia PCLO 27445 piccolo (presynaptic cytomatrix protein) 7q11.23-q21.3 16078 13406 604918 "NP_055325;NP_149015" "NM_014510;NM_033026" ENSP00000388393 candidate 0 0 0 Last Universal Common Ancestor 4 0 Cellular processes,Multicellular activities,Signal transduction 72 chr7 82387894 82791908 WES chronic lymphocytic leukemia,lymphoma PCM1 5108 pericentriolar material 1 8p22-p21.3 2624 8727 600299 NP_006188 NM_006197 - known 1 0 0 Eukaryotes 40 0 Cellular processes,Development 99 chr8 17793120 17883166 CGC leukemia,myeloma,thyroid PCMTD1 115294 protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 1 8q11.23 8313 30483 - NP_443169 NM_052937 ENSP00000353739 candidate 0 0 0 Last Universal Common Ancestor 4 1 Cellular metabolism,Cellular processes -1 chr8 52732914 52773711 WGS lymphoma PCSK6 5046 proprotein convertase subtilisin/kexin type 6 15q26.3 1329 8569 167405 "NP_612198;NP_612197;NP_612195;NP_612192;NP_002561;NP_612196;NP_612193;NP_612194" "NM_138325;NM_138324;NM_138322;NM_138319;NM_002570;NM_138323;NM_138320;NM_138321" "ENSP00000305056;ENSP00000351193;ENSP00000381243;ENSP00000344410" candidate 0 0 0 Last Universal Common Ancestor 7 0 Cell cycle,Cellular metabolism,Cellular processes,Development,Regulation of intracellular processes and metabolism,Signal transduction 72 chr15 101853355 102029686 WES pancreas PCSK7 9159 proprotein convertase subtilisin/kexin type 7 11q23-q24 5339 8748 604872 NP_004707 NM_004716 - known 1 0 0 Last Universal Common Ancestor 0 0 Cellular metabolism,Cellular processes 50 chr11 117076716 117100560 CGC lymphoma PDCD11 22984 programmed cell death 11 10q24.33 18752 13408 612333 NP_055791 NM_014976 ENSP00000358812 candidate 0 0 0 Last Universal Common Ancestor 5 2 DNA/RNA metabolism and transcription,Regulation of transcription 99 chr10 105158184 105205303 WES,WGS breast,prostate PDCD1LG2 80380 programmed cell death 1 ligand 2 9p24.2 16147 18731 605723 NP_079515 NM_025239 ENSP00000380855 known 1 0 0 Vertebrates 1 0 -1 2 chr9 5522547 5563211 CGC lymphoma PDCD6 10016 programmed cell death 6 5p15.33 3035 8765 601057 NP_037364 NM_013232 "ENSP00000423815;ENSP00000264933" candidate 0 0 0 Vertebrates 47 0 Cell cycle,Cell response to stimuli,Development,Regulation of intracellular processes and metabolism 108 chr5 271836 314627 WES pancreas PDE1B 5153 phosphodiesterase 1B, calmodulin-dependent 12q13 1388 8775 171891 "NP_001159447;NP_000915" "NM_001165975;NM_000924" ENSP00000243052 candidate 0 0 0 Eukaryotes 2 0 Cell cycle,Signal transduction 7 chr12 54943657 54971109 WGS lung PDE4B 5142 phosphodiesterase 4B, cAMP-specific 1p31 2528 8781 600127 "NP_001032416;NP_001032418;NP_002591;NP_001032417" "NM_001037339;NM_001037341;NM_002600;NM_001037340" "ENSP00000360084;ENSP00000392947;ENSP00000332116" candidate 0 0 0 Eukaryotes 7 0 Signal transduction 88 chr1 66378998 66838358 WGS liver PDE4DIP 9659 phosphodiesterase 4D interacting protein 1q12 10482 15580 608117 "NP_001185763;NP_071754;NP_001185761;NP_055459;NP_001002810;NP_001182189;NP_001002811;NP_001182190;NP_001002812" "NM_001198834;NM_022359;NM_001198832;NM_014644;NM_001002810;NM_001195260;NM_001002811;NM_001195261;NM_001002812" "ENSP00000358353;ENSP00000316434;ENSP00000358355;ENSP00000327209;ENSP00000358363;ENSP00000358360;ENSP00000358354" known 1 0 0 Metazoans 42 0 Cellular processes 70 chr1 144852357 144994731 CGC,WGS myeloma,chronic lymphocytic leukemia PDGFB 5155 platelet-derived growth factor beta polypeptide 22q12.3-q13.1|22q13.1 1815 8800 190040 "NP_002599;NP_148937" "NM_002608;NM_033016" ENSP00000330382 known 1 0 0 Vertebrates 15 2 Cell cycle,Cell motility and interactions,Cell response to stimuli,Cellular metabolism,DNA/RNA metabolism and transcription,Development,Immune system response,Multicellular activities,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction 76 chr22 39621731 39639968 CGC sarcoma PDGFC 56034 platelet derived growth factor C 4q32 10529 8801 608452 NP_057289 "NM_016205;NR_036641" - candidate 0 0 0 Eukaryotes 29 7 Development 90 chr4 157684245 157892055 WES,WGS lymphoma,lung PDGFRA 5156 platelet-derived growth factor receptor, alpha polypeptide 4q12 1429 8803 173490 NP_006197 NM_006206 ENSP00000257290 known 1 0 0 Last Universal Common Ancestor 36 2 Cell cycle,Cell motility and interactions,Cellular metabolism,Cellular processes,DNA/RNA metabolism and transcription,Development,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction 84 chr4 55124936 55161436 CGC,HTMS gastric,glioblastoma,idiopathic hypereosinophilic syndrome,lung PDGFRB 5159 platelet-derived growth factor receptor, beta polypeptide 5q33.1 1423 8804 173410 NP_002600 NM_002609 ENSP00000261799 known 1 0 0 Last Universal Common Ancestor 102 1 Cell cycle,Cell motility and interactions,Cellular metabolism,Cellular processes,Regulation of intracellular processes and metabolism,Signal transduction 68 chr5 149495329 149515445 CGC leukemia,myeloma PDIA4 9601 protein disulfide isomerase family A, member 4 7q35 6501 30167 - NP_004902 NM_004911 ENSP00000286091 candidate 0 0 0 Last Universal Common Ancestor 25 1 Cellular processes,Regulation of intracellular processes and metabolism 106 chr7 148700889 148725500 HTMS breast,lung,ovarian,pancreas,prostate PDYN 5173 prodynorphin 20p13 8838 8820 131340 "NP_077722;NP_001177829;NP_001177821;NP_001177827;NP_001177828" "NM_024411;NM_001190900;NM_001190892;NM_001190898;NM_001190899" "ENSP00000440185;ENSP00000442259;ENSP00000217305" candidate 0 0 0 Vertebrates 2 0 Multicellular activities,Signal transduction 20 chr20 1960972 1963730 WES lung PDZRN3 23024 PDZ domain containing ring finger 3 3p13 15115 17704 609729 NP_055824 NM_015009 ENSP00000263666 candidate 0 0 0 Metazoans 0 0 -1 47 chr3 73432519 73673976 WES pancreas PEAR1 375033 platelet endothelial aggregation receptor 1 1q23.1 - 33631 610278 NP_001073940 "NM_207369;NM_001080471" ENSP00000292357 candidate 0 0 0 Eukaryotes 0 0 -1 -1 chr1 156873719 156884587 WES pancreas PEG3 5178 paternally expressed 3 19q13.4 3285 8826 601483 "NP_001139659;NP_006201;NP_001139656;NP_001139658;NP_001139657" "NM_001146187;NM_006210;NM_001146184;NM_001146186;NM_001146185" "ENSP00000403051;ENSP00000326581" candidate 0 0 0 Last Universal Common Ancestor 12 1 Cell cycle,Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription 87 chr19 57325046 57336023 WES cholangiocarcinoma PER1 5187 period homolog 1 (Drosophila) 17p13.1 3774 8845 602260 NP_002607 NM_002616 ENSP00000314420 known 1 0 0 Eukaryotes 18 1 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction 105 chr17 8044389 8054024 CGC leukemia PFKP 5214 phosphofructokinase, platelet 10p15.3-p15.2 1384 8878 171840 "NP_001229268;NP_002618" "NM_001242339;NM_002627" "ENSP00000370465;ENSP00000370517" candidate 0 0 0 Last Universal Common Ancestor 35 4 Cellular metabolism 96 chr10 3109788 3178768 WGS medulloblastoma PGAP2 27315 post-GPI attachment to proteins 2 11p15.5 17016 17893 - "NP_001243168;NP_055304;NP_001138910;NP_001243164;NP_001243169;NP_001243167;NP_001243165;NP_001243166" "NR_027016;NR_045925;NM_001256239;NM_014489;NM_001145438;NM_001256235;NM_001256240;NR_045927;NM_001256238;NR_045929;NM_001256236;NR_027014;NR_027017;NR_027018;NR_045926;NM_001256237;NR_027015;NR_045923" "ENSP00000300730;ENSP00000431851;ENSP00000278243" candidate 0 0 0 Eukaryotes 0 0 Cellular metabolism,Cellular processes 74 chr11 3819074 3846685 WES lymphoma PHC2 1912 polyhomeotic homolog 2 (Drosophila) 1p34.3 10340 3183 602979 "NP_004418;NP_932157" "NM_004427;NM_198040" "ENSP00000362517;ENSP00000257118" candidate 0 0 0 Eukaryotes 58 9 -1 107 chr1 33790469 33841140 WES chronic lymphocytic leukemia PHF3 23469 PHD finger protein 3 6q12 8477 8921 607789 NP_055968 NM_015153 ENSP00000377048 candidate 0 0 0 Eukaryotes 4 4 Cellular metabolism,DNA/RNA metabolism and transcription 92 chr6 64356457 64423601 WES pancreas PHF6 84295 PHD finger protein 6 Xq26.3 2330 18145 300414 "NP_001015877;NP_115711;NP_115834" "NM_001015877;NM_032335;NM_032458" "ENSP00000359839;ENSP00000359836;ENSP00000329097" known 0 1 0 Eukaryotes 8 6 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription -1 chrX 133511648 133559357 CGC leukemia PHIP 55023 pleckstrin homology domain interacting protein 6q14 10152 15673 612870 NP_060404 NM_017934 - candidate 0 0 0 Last Universal Common Ancestor 37 3 Signal transduction 67 chr6 79650413 79787785 WES glioblastoma PHOX2B 8929 paired-like homeobox 2b 4p12 9157 9143 603851 NP_003915 NM_003924 ENSP00000226382 known 0 1 0 Eukaryotes 1 0 Cell cycle,Cellular metabolism,DNA/RNA metabolism and transcription,Development,Regulation of intracellular processes and metabolism,Regulation of transcription 39 chr4 41747827 41750627 CGC neuroblastoma PI4KA 5297 phosphatidylinositol 4-kinase, catalytic, alpha 22q11.21 8972 8983 600286 "NP_002641;NP_477352" "NM_002650;NM_058004" "ENSP00000402981;ENSP00000255882" candidate 0 0 0 Eukaryotes 17 0 Cellular metabolism,Cellular processes,Multicellular activities,Signal transduction 102 chr22 21062338 21213013 HTMS sarcoma PICALM 8301 phosphatidylinositol binding clathrin assembly protein 11q14 4320 15514 603025 "NP_009097;NP_001193875;NP_001008660;NP_001193876" "NM_007166;NM_001206946;NM_001008660;NM_001206947" "ENSP00000436958;ENSP00000433846" known 1 0 0 Eukaryotes 3 8 Cellular processes 105 chr11 85685751 85779822 CGC leukemia PID1 55022 phosphotyrosine interaction domain containing 1 2q36.3 7944 26084 612930 "NP_060403;NP_001094288" "NM_017933;NM_001100818" "ENSP00000375908;ENSP00000375907" candidate 0 0 0 Metazoans 2 0 -1 85 chr2 229890351 230020680 WGS breast PIK3AP1 118788 phosphoinositide-3-kinase adaptor protein 1 10q24.1 6401 30034 607942 NP_689522 NM_152309 ENSP00000339826 candidate 0 0 0 Metazoans 8 0 -1 -1 chr10 98355337 98469741 WES head and neck squamous cell carcinoma PIK3C2G 5288 phosphoinositide-3-kinase, class 2, gamma polypeptide 12p12 16416 8973 609001 NP_004561 NM_004570 ENSP00000404845 candidate 0 0 0 Eukaryotes 1 0 Cellular metabolism,Cellular processes,Signal transduction 31 chr12 18435016 18800959 HTMS breast,lung,ovarian,pancreas,prostate PIK3CA 5290 phosphoinositide-3-kinase, catalytic, alpha polypeptide 3q26.3 1382 8975 171834 NP_006209 NM_006218 - known 1 0 0 Eukaryotes 65 2 Cellular metabolism,Cellular processes,Signal transduction 36 chr3 178916614 178952149 CGC,HTMS,WES,WGS,Amplified breast,colorectal,gastric,glioblastoma,lung,ovarian,pancreas,prostate,sarcoma,colorectal (non-hypermutated),endometrium,head and neck squamous cell carcinoma,oligodendroglioma,medulloblastoma PIK3CG 5294 phosphoinositide-3-kinase, catalytic, gamma polypeptide 7q22.3 3135 8978 601232 NP_002640 NM_002649 ENSP00000352121 candidate 0 0 0 Eukaryotes 37 2 Cell cycle,Cellular metabolism,Cellular processes,Development,Regulation of intracellular processes and metabolism,Signal transduction 2 chr7 106508007 106545829 HTMS breast,lung,ovarian,pancreas,prostate PIK3R1 5295 phosphoinositide-3-kinase, regulatory subunit 1 (alpha) 5q13.1 1381 8979 171833 "NP_001229395;NP_852556;NP_852664;NP_852665" "NM_001242466;NM_181504;NM_181523;NM_181524" ENSP00000428056 known 0 1 0 Metazoans 310 6 Cellular metabolism,Cellular processes,Signal transduction 99 chr5 67522504 67593426 CGC,HTMS,WES colorectal,glioblastoma,ovarian,breast,lung,pancreas,prostate,oligodendroglioma PIK3R2 5296 phosphoinositide-3-kinase, regulatory subunit 2 (beta) 19q13.2-q13.4 4404 8980 603157 NP_005018 NM_005027 ENSP00000222254 candidate 0 0 0 Metazoans 115 3 Cell cycle,Development,Regulation of intracellular processes and metabolism,Signal transduction 90 chr19 18266690 18280101 WGS chronic lymphocytic leukemia PIM1 5292 pim-1 oncogene 6p21.2 1292 8986 164960 "NP_002639;NP_001230115" "NM_002648;NM_001243186" ENSP00000362608 known 1 0 0 Last Universal Common Ancestor 36 9 Cell cycle,Cellular metabolism,Cellular processes,Development,Regulation of intracellular processes and metabolism 102 chr6 37138082 37141864 CGC,WES non-hodgkin lymphoma,lymphoma PKDREJ 10343 polycystic kidney disease (polycystin) and REJ homolog (sperm receptor for egg jelly homolog, sea urchin) 22q13.31 5239 9015 604670 NP_006062 NM_006071 ENSP00000253255 candidate 0 0 0 Eukaryotes 7 0 Cellular processes,Development,Signal transduction 2 chr22 46652461 46659219 WGS breast PKHD1 5314 polycystic kidney and hepatic disease 1 (autosomal recessive) 6p12.2 5987 9016 606702 "NP_619639;NP_733842" "NM_138694;NM_170724" "ENSP00000360158;ENSP00000341097" candidate 0 0 0 Last Universal Common Ancestor 1 0 Cell motility and interactions,Regulation of intracellular processes and metabolism -1 chr6 51483882 51949731 HTMS,WES breast,lung,ovarian,pancreas,prostate,gastric,glioblastoma PKHD1L1 93035 polycystic kidney and hepatic disease 1 (autosomal recessive)-like 1 8q23 9703 20313 607843 NP_803875 NM_177531 ENSP00000367655 candidate 0 0 0 Last Universal Common Ancestor 0 1 -1 -1 chr8 110374810 110539248 WES head and neck squamous cell carcinoma PKN1 5585 protein kinase N1 19p13.12 3019 9405 601032 "NP_998725;NP_002732" "NM_213560;NM_002741" "ENSP00000242783;ENSP00000343325" candidate 0 0 0 Last Universal Common Ancestor 10 1 Cellular metabolism,Cellular processes,Regulation of intracellular processes and metabolism,Signal transduction 36 chr19 14551103 14582593 WGS melanoma PKNOX1 5316 PBX/knotted 1 homeobox 1 21q22.3 3653 9022 602100 NP_004562 NM_004571 ENSP00000291547 candidate 0 0 0 Eukaryotes 14 1 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription 40 chr21 44424492 44450208 WES colorectal PKP4 8502 plakophilin 4 2q24.1 5043 9026 604276 "NP_001005476;NP_003619" "NM_001005476;NM_003628" ENSP00000374409 candidate 0 0 0 Eukaryotes 22 2 -1 86 chr2 159389697 159537186 WES head and neck squamous cell carcinoma PLA2G10 8399 phospholipase A2, group X 16p13.1-p12 4674 9029 603603 NP_003552 NM_003561 ENSP00000393847 known 0 0 0 Metazoans 3 1 Cellular metabolism 39 chr16 14766467 14784503 CGC,Amplified PLA2G4F 255189 phospholipase A2, group IVF 15q15.1 17326 27396 - NP_998765 "NM_213600;NR_033151" ENSP00000371833 candidate 0 0 0 Eukaryotes 1 0 Cellular metabolism -1 chr15 42434185 42448747 WGS lymphoma PLAG1 5324 pleiomorphic adenoma gene 1 8q12 4321 9045 603026 "NP_001108107;NP_001108106;NP_002646" "NM_001114635;NM_001114634;NM_002655" ENSP00000325546 known 1 0 0 Last Universal Common Ancestor 2 23 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription 19 chr8 57078805 57080828 CGC salivary PLB1 151056 phospholipase B1 2p23.2 15141 30041 610179 "NP_001164056;NP_694566" "NM_001170585;NM_153021" "ENSP00000416440;ENSP00000330442" candidate 0 0 0 Eukaryotes 1 0 Cellular metabolism -1 chr2 28718982 28865924 WES colorectal PLCB4 5332 phospholipase C, beta 4 20p12 2885 9059 600810 "NP_001166117;NP_877949;NP_000924" "NM_001172646;NM_182797;NM_000933" "ENSP00000367762;ENSP00000367734;ENSP00000278655" candidate 0 0 0 Eukaryotes 2 4 Cellular metabolism,Signal transduction 45 chr20 9288462 9459653 WES,WGS melanoma PLCG2 5336 phospholipase C, gamma 2 (phosphatidylinositol-specific) 16q24.1 2570 9066 600220 NP_002652 NM_002661 ENSP00000352336 candidate 0 0 0 Eukaryotes 8 1 Cellular metabolism,Signal transduction 99 chr16 81819595 81991600 WES colorectal PLCH2 9651 phospholipase C, eta 2 1p36.32 - 29037 612836 NP_055453 NM_014638 ENSP00000367747 candidate 0 0 0 Eukaryotes 1 1 Cellular metabolism,Signal transduction 25 chr1 2408028 2436649 WGS melanoma PLD2 5338 phospholipase D2 17p13.1 3857 9068 602384 "NP_002654;NP_001230037" "NM_002663;NM_001243108" "ENSP00000459571;ENSP00000263088" candidate 0 0 0 Last Universal Common Ancestor 38 0 Cellular metabolism,Cellular processes,Regulation of intracellular processes and metabolism,Signal transduction 58 chr17 4711068 4726156 WES breast PLEC 5339 plectin 8q24 3180 9069 601282 "NP_958782;NP_958786;NP_000436;NP_958784;NP_958785;NP_958780;NP_958783;NP_958781" "NM_201380;NM_201384;NM_000445;NM_201382;NM_201383;NM_201378;NM_201381;NM_201379" "ENSP00000388180;ENSP00000348702;ENSP00000347044;ENSP00000323856;ENSP00000381756;ENSP00000346602;ENSP00000350277;ENSP00000344848" candidate 0 0 0 Eukaryotes 53 8 -1 70 chr8 144990348 145024874 WGS lymphoma PLEKHA8 84725 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 8 7p21-p11.2 10555 30037 608639 "NP_116028;NP_001183955;NP_001183956" "NM_032639;NM_001197026;NM_001197027" ENSP00000258679 candidate 0 0 1 Eukaryotes 4 2 Cellular processes 0 chr7 30068379 30118400 WES breast PLEKHG4B 153478 pleckstrin homology domain containing, family G (with RhoGef domain) member 4B 5p15.33 13900 29399 - NP_443141 NM_052909 - candidate 0 0 0 Metazoans 1 0 Signal transduction -1 chr5 140423 182435 WGS lymphoma PLEKHG5 57449 pleckstrin homology domain containing, family G (with RhoGef domain) member 5 1p36.31 11104 29105 611101 "NP_001036129;NP_001036128;NP_001036130;NP_941374;NP_065682" "NM_001042664;NM_001042663;NM_001042665;NM_198681;NM_020631" "ENSP00000344570;ENSP00000383704;ENSP00000366977" candidate 0 0 0 Metazoans 21 0 Regulation of intracellular processes and metabolism,Signal transduction -1 chr1 6527878 6579571 WGS liver PLSCR4 57088 phospholipid scramblase 4 3q24 7401 16497 607612 "NP_001121778;NP_065086;NP_001170775;NP_001121776;NP_001121777" "NR_033438;NM_001128306;NR_033439;NM_020353;NM_001177304;NM_001128304;NM_001128305" "ENSP00000372561;ENSP00000415605;ENSP00000347038" candidate 0 0 0 Eukaryotes 16 8 Cellular processes,Multicellular activities 87 chr3 145912201 145938713 WES lung PML 5371 promyelocytic leukemia 15q22 23 9113 102578 "NP_150250;NP_002666;NP_150253;NP_150252;NP_150243;NP_150247;NP_150249;NP_150242;NP_150241" "NM_033247;NM_002675;NM_033250;NM_033249;NM_033240;NM_033244;NM_033246;NM_033239;NM_033238" "ENSP00000378567;ENSP00000268058;ENSP00000268059;ENSP00000395576;ENSP00000394642;ENSP00000353004;ENSP00000378564;ENSP00000457023;ENSP00000315434" known 1 0 0 Eukaryotes 38 1 Cell cycle,Cell response to stimuli,Cellular metabolism,Cellular processes,DNA/RNA metabolism and transcription,Development,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction 91 chr15 74287154 74337346 CGC leukemia PMS1 5378 PMS1 postmeiotic segregation increased 1 (S. cerevisiae) 2q31-q33|2q31.1 2597 9121 600258 "NP_001121615;NP_001121616;NP_000525" "NM_001128143;NM_001128144;NM_000534" "ENSP00000406490;ENSP00000387125;ENSP00000401064" known 0 1 0 Last Universal Common Ancestor 49 2 Cell cycle,Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription 94 chr2 190656536 190742159 CGC,WES lymphoma PMS2 5395 PMS2 postmeiotic segregation increased 2 (S. cerevisiae) 7p22.2 2598 9122 600259 NP_000526 "NR_003085;NM_000535" ENSP00000265849 known 0 1 0 Last Universal Common Ancestor 45 0 Cell cycle,Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism 8 chr7 6013033 6045667 CGC PMS2P3 5387 postmeiotic segregation increased 2 pseudogene 3 7q11.23 17866 9128 - - "NM_005395;NM_001003686;NR_028059" - candidate 0 0 -1 - 0 0 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription 102 - 0 0 WES gastric PNLIPRP2 5408 pancreatic lipase-related protein 2 10q25.3 5110 9157 604423 NP_005387 NM_005396 ENSP00000424858 candidate 0 0 0 Primates 0 2 Cell response to stimuli,Cellular metabolism 25 chr10 118380818 118404605 WGS glioblastoma PNPLA7 375775 patatin-like phospholipase domain containing 7 9q34.3 12933 24768 612122 "NP_001092007;NP_689499" "NM_001098537;NM_152286" "ENSP00000384610;ENSP00000277531" candidate 0 0 0 Last Universal Common Ancestor 0 0 -1 -1 chr9 140354848 140442114 WES chronic lymphocytic leukemia PNRC1 10957 proline-rich nuclear receptor coactivator 1 6q15 8412 17278 606714 NP_006804 NM_006813 ENSP00000336931 candidate 0 0 0 Metazoans 15 2 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription 107 chr6 89790614 89793912 WES,WGS myeloma POC5 134359 POC5 centriolar protein homolog (Chlamydomonas) 5q13.3 8188 26658 - "NP_001092741;NP_689621" "NM_001099271;NM_152408" "ENSP00000410216;ENSP00000399481" candidate 0 0 0 Eukaryotes 1 0 -1 -1 chr5 74970263 75008762 WGS lung POF1B 79983 premature ovarian failure, 1B Xq21.2 6679 13711 300603 NP_079197 NM_024921 ENSP00000262753 candidate 0 0 0 Vertebrates 5 0 -1 18 chrX 84537209 84634459 WES chronic lymphocytic leukemia POLK 51426 polymerase (DNA directed) kappa 5q13 9291 9183 605650 NP_057302 NM_016218 - candidate 0 0 0 Last Universal Common Ancestor 21 2 Cellular metabolism,DNA/RNA metabolism and transcription -1 chr5 74842848 74893840 WGS chronic lymphocytic leukemia POLR3A 11128 polymerase (RNA) III (DNA directed) polypeptide A, 155kDa 10q22-q23 17879 30074 614258 NP_008986 NM_007055 ENSP00000361446 candidate 0 0 0 Last Universal Common Ancestor 2 2 Cellular metabolism,DNA/RNA metabolism and transcription -1 chr10 79737239 79789165 WGS prostate POT1 25913 protection of telomeres 1 homolog (S. pombe) 7q31.33 7572 17284 606478 "NP_001036059;NP_056265" "NR_003104;NM_001042594;NR_003103;NR_003102;NM_015450" "ENSP00000377002;ENSP00000350249" candidate 0 0 0 Eukaryotes 25 0 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism 77 chr7 124464019 124532434 WES chronic lymphocytic leukemia POTEC 388468 POTE ankyrin domain family, member C 18p11.21 - 33894 - NP_001131143 NM_001137671 - candidate 0 0 10 Last Universal Common Ancestor 0 0 -1 -1 chr18 14511900 14543145 WES melanoma POTED 317754 POTE ankyrin domain family, member D 21q11.2 9612 23822 607549 NP_778146 NM_174981 ENSP00000299443 candidate 0 0 10 Last Universal Common Ancestor 0 0 -1 -1 chr21 14982550 15013884 WGS melanoma POU2AF1 5450 POU class 2 associating factor 1 11q23.1 3126 9211 601206 NP_006226 NM_006235 ENSP00000376786 known 1 0 0 Vertebrates 1 0 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription 29 chr11 111224989 111229641 CGC non-hodgkin lymphoma POU2F2 5452 POU class 2 homeobox 2 19q13.2 1251 9213 164176 "NP_001193955;NP_001234923;NP_001193954;NP_002689" "NM_001207026;NM_001247994;NM_001207025;NM_002698" ENSP00000436988 candidate 0 0 0 Metazoans 1 1 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription 52 chr19 42595707 42626732 WES lymphoma POU5F1 5460 POU class 5 homeobox 1 6p21.31 1252 9221 164177 "NP_001167002;NP_976034;NP_002692" "NM_001173531;NM_203289;NM_002701" "ENSP00000425479;ENSP00000425083" known 1 0 3 Vertebrates 62 1 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription 0 chr6 31132381 31138397 CGC sarcoma PPARG 5468 peroxisome proliferator-activated receptor gamma 3p25 3288 9236 601487 "NP_005028;NP_619726;NP_619725;NP_056953" "NM_005037;NM_138712;NM_138711;NM_015869" "ENSP00000380210;ENSP00000287820;ENSP00000380207;ENSP00000312472" known 1 0 0 Metazoans 108 8 Cell cycle,Cell response to stimuli,Cellular metabolism,Cellular processes,DNA/RNA metabolism and transcription,Development,Immune system response,Multicellular activities,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction 9 chr3 12393092 12475641 CGC thyroid PPM1D 8493 protein phosphatase, Mg2+/Mn2+ dependent, 1D 17q23.2 5482 9277 605100 NP_003611 NM_003620 - known 0 0 0 Last Universal Common Ancestor 10 7 Cell cycle,Cellular metabolism,Cellular processes,Regulation of intracellular processes and metabolism 65 chr17 58677776 58740910 CGC,Amplified PPM1E 22843 protein phosphatase, Mg2+/Mn2+ dependent, 1E 17q22 17888 19322 - NP_055721 NM_014906 - candidate 0 0 0 Last Universal Common Ancestor 5 1 Cellular metabolism,Cellular processes 14 chr17 56833359 57058389 WES breast PPM1L 151742 protein phosphatase, Mg2+/Mn2+ dependent, 1L 3q26.1 17889 16381 611931 NP_640338 NM_139245 - candidate 0 0 0 Last Universal Common Ancestor 2 2 Cellular metabolism,Cellular processes -1 chr3 160474097 160786942 HTMS breast,lung,ovarian,pancreas,prostate PPP1R3A 5506 protein phosphatase 1, regulatory subunit 3A 7q31.1 2950 9291 600917 NP_002702 NM_002711 ENSP00000284601 candidate 0 0 0 Last Universal Common Ancestor 1 1 Cellular metabolism 9 chr7 113517781 113559051 HTMS,WES breast,lung,ovarian,pancreas,prostate PPP1R9A 55607 protein phosphatase 1, regulatory subunit 9A 7q21.3 - 14946 602468 "NP_060120;NP_001159632;NP_001159634;NP_001159633;NP_001159635" "NM_017650;NM_001166160;NM_001166162;NM_001166161;NM_001166163" "ENSP00000289495;ENSP00000402893;ENSP00000344524" candidate 0 0 0 Opisthokonts 12 3 Development 53 chr7 94539426 94919612 WES,WGS head and neck squamous cell carcinoma,chronic lymphocytic leukemia PPP2R1A 5518 protein phosphatase 2, regulatory subunit A, alpha 19q13.41 16184 9302 605983 NP_055040 "NR_033500;NM_014225" - known 1 0 1 Eukaryotes 100 2 Cell cycle,Cell motility and interactions,Cellular metabolism,Cellular processes,DNA/RNA metabolism and transcription,Development,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction 93 chr19 52693350 52729060 CGC,WES ovarian,endometrium PPP2R2B 5521 protein phosphatase 2, regulatory subunit B, beta 5q32 5059 9305 604325 "NP_004567;NP_858060;NP_858062;NP_858061;NP_858063;NP_001120853;NP_858064" "NM_004576;NM_181674;NM_181676;NM_181675;NM_181677;NM_001127381;NM_181678" "ENSP00000349283;ENSP00000377933;ENSP00000336591;ENSP00000421396;ENSP00000377932" candidate 0 0 3 Eukaryotes 207 0 Signal transduction 77 chr5 145969513 146435306 WGS prostate PPP2R5A 5525 protein phosphatase 2, regulatory subunit B', alpha 1q32.2-q32.3 3384 9309 601643 "NP_006234;NP_001186685" "NM_006243;NM_001199756" ENSP00000261461 candidate 0 0 0 Eukaryotes 35 3 Signal transduction 80 chr1 212459453 212534109 WES lymphoma PPP6R2 9701 protein phosphatase 6, regulatory subunit 2 22q13.33 11102 19253 610877 "NP_055493;NP_001229828;NP_001229829;NP_001229827" "NM_014678;NM_001242899;NM_001242900;NM_001242898" "ENSP00000379090;ENSP00000352051;ENSP00000379093" candidate 0 0 0 Eukaryotes 12 4 -1 69 chr22 50832338 50882673 WES lymphoma PPPDE1 51029 PPPDE peptidase domain containing 1 1q44 15153 24264 - NP_057160 NM_016076 ENSP00000306528 candidate 0 0 0 Eukaryotes 1 0 -1 100 chr1 244816616 244869088 WGS breast PPYR1 5540 pancreatic polypeptide receptor 1 10q11.2 3476 9329 601790 NP_005963 NM_005972 ENSP00000363431 candidate 0 0 0 Metazoans 0 1 Multicellular activities,Signal transduction 11 chr10 47086784 47087908 WGS glioblastoma PRB4 5545 proline-rich protein BstNI subfamily 4 12p13.2 1624 9340 180990 NP_002714 NM_002723 "ENSP00000412740;ENSP00000279575" candidate 0 0 7 - 1 0 -1 2 chr12 11461176 11463332 WES head and neck squamous cell carcinoma PRC1 9055 protein regulator of cytokinesis 1 15q26.1 17899 9341 603484 "NP_003972;NP_955446;NP_955445" "NM_003981;NM_199414;NM_199413" "ENSP00000377793;ENSP00000354618" candidate 0 0 0 Eukaryotes 19 2 Cell cycle,Cellular processes 32 chr15 91510364 91528057 WGS melanoma PRCC 5546 papillary renal cell carcinoma (translocation-associated) 1q21.1 1562 9343 179755 NP_005964 "NM_005973;NM_199416" ENSP00000271526 known 1 0 0 Eukaryotes 11 0 -1 50 chr1 156737564 156770249 CGC kidney PRDM1 639 PR domain containing 1, with ZNF domain 6q21 4572 9346 603423 "NP_878911;NP_001189" "NM_182907;NM_001198" "ENSP00000358092;ENSP00000358085" known 0 1 0 Last Universal Common Ancestor 22 12 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription 26 chr6 106534429 106555358 CGC,WES lymphoma PRDM16 63976 PR domain containing 16 1p36.23-p33 16122 14000 605557 "NP_071397;NP_955533" "NM_022114;NM_199454" "ENSP00000270722;ENSP00000405253" known 1 0 0 Last Universal Common Ancestor 7 4 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription 11 chr1 3102691 3350372 CGC leukemia,myelodysplasia PRDM2 7799 PR domain containing 2, with ZNF domain 1p36.21 3120 9347 601196 "NP_001129082;NP_001007258;NP_036363;NP_056950" "NM_001135610;NM_001007257;NM_012231;NM_015866" "ENSP00000411103;ENSP00000365216;ENSP00000235372;ENSP00000312352" candidate 0 0 0 Eukaryotes 10 0 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription 103 chr1 14057492 14143039 WGS prostate PRDM9 56979 PR domain containing 9 5p14 17905 13994 609760 NP_064612 NM_020227 ENSP00000296682 candidate 0 0 0 Last Universal Common Ancestor 0 0 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription 1 chr5 23509579 23527879 WES chronic lymphocytic leukemia,colorectal,head and neck squamous cell carcinoma,lung PREX2 80243 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2 8q13.2 13135 22950 612139 "NP_079146;NP_079446" "NM_024870;NM_025170" - candidate 0 0 0 Eukaryotes 5 1 Signal transduction 36 chr8 68864630 69143610 WES,WGS pancreas,melanoma PRF1 5551 perforin 1 (pore forming protein) 10q22 1362 9360 170280 "NP_005032;NP_001076585" "NM_005041;NM_001083116" "ENSP00000398568;ENSP00000316746" known 0 1 0 Metazoans 5 0 Cell cycle,Cell response to stimuli,Cellular processes,Other 75 chr10 72357812 72360658 CGC PRG4 23572 p53-responsive gene 4 - - - 605160 - - - candidate 0 0 -1 Last Universal Common Ancestor 0 3 -1 -1 - 0 0 WGS melanoma PRKAB2 5565 protein kinase, AMP-activated, beta 2 non-catalytic subunit 1q21.1 4117 9379 602741 NP_005390 NM_005399 ENSP00000254101 candidate 0 0 0 Eukaryotes 28 6 Cellular metabolism,Cellular processes,Regulation of intracellular processes and metabolism,Signal transduction 56 chr1 146631147 146643723 HTMS breast,lung,ovarian,pancreas,prostate PRKAR1A 5573 protein kinase, cAMP-dependent, regulatory, type I, alpha (tissue specific extinguisher 1) 17q23-q24 1786 9388 188830 "NP_002725;NP_997637;NP_997636" "NM_002734;NM_212472;NM_212471" "ENSP00000464977;ENSP00000351410;ENSP00000376475" known 1 1 2 Last Universal Common Ancestor 55 5 Cellular metabolism,Cellular processes,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction 108 chr17 66511541 66526587 CGC,HTMS thyroid,breast,lung,ovarian,pancreas,prostate PRKCB 5579 protein kinase C, beta 16p11.2 1499 9395 176970 "NP_002729;NP_997700" "NM_002738;NM_212535" "ENSP00000305355;ENSP00000318315" candidate 0 0 1 Last Universal Common Ancestor 2 3 Cellular metabolism,Cellular processes,Signal transduction 100 chr16 23847497 24226134 HTMS breast,lung,ovarian,pancreas,prostate PRKCG 5582 protein kinase C, gamma 19q13.4 1502 9402 176980 NP_002730 NM_002739 ENSP00000263431 candidate 0 0 0 Last Universal Common Ancestor 6 1 Cell response to stimuli,Cellular metabolism,Cellular processes,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction 3 chr19 54385749 54410146 WES pancreas PRKCI 5584 protein kinase C, iota 3q26.3 2105 9404 600539 NP_002731 NM_002740 ENSP00000295797 known 0 0 1 Last Universal Common Ancestor 35 1 Cell cycle,Cell motility and interactions,Cellular metabolism,Cellular processes,Development,Signal transduction 103 chr3 169940458 170020912 CGC,WGS,Amplified prostate PRKD1 5587 protein kinase D1 14q11 5668 9407 605435 NP_002733 NM_002742 ENSP00000333568 candidate 0 0 0 Last Universal Common Ancestor 7 1 Cellular metabolism,Cellular processes,Signal transduction 68 chr14 30046447 30396718 WES colorectal PRKG2 5593 protein kinase, cGMP-dependent, type II 4q13.1-q21.1 9034 9416 601591 NP_006250 NM_006259 ENSP00000264399 candidate 0 0 0 Last Universal Common Ancestor 1 3 Cellular metabolism,Cellular processes,Signal transduction 58 chr4 82010865 82126201 WGS breast PRKX 5613 protein kinase, X-linked Xp22.3 2097 9441 300083 NP_005035 NM_005044 ENSP00000262848 candidate 0 0 2 Last Universal Common Ancestor 4 1 Cellular metabolism,Cellular processes 37 chrX 3530244 3631294 WES melanoma PRLR 5618 prolactin receptor 5p13.2 1457 9446 176761 "NP_001191244;NP_001191247;NP_000940;NP_001191243;NP_001191245;NP_001191246" "NM_001204315;NM_001204318;NM_000949;NM_001204314;NM_001204316;NR_037910;NM_001204317" "ENSP00000371432;ENSP00000339213;ENSP00000309008;ENSP00000231423;ENSP00000424841;ENSP00000311613" candidate 0 0 0 Metazoans 5 2 Cell cycle,Cellular metabolism,Cellular processes,Development,Immune system response,Multicellular activities,Regulation of intracellular processes and metabolism,Signal transduction 44 chr5 35065194 35089722 WES chronic lymphocytic leukemia PROK2 60675 prokineticin 2 3p13 8446 18455 607002 "NP_068754;NP_001119600" "NM_021935;NM_001126128" ENSP00000295618 candidate 0 0 0 Metazoans 0 1 Cell cycle,Cell motility and interactions,Cell response to stimuli,Cellular metabolism,Cellular processes,Development,Immune system response,Multicellular activities,Regulation of intracellular processes and metabolism,Signal transduction -1 chr3 71821878 71834203 WGS melanoma PROKR2 128674 prokineticin receptor 2 20p12.3 8453 15836 607123 NP_658986 NM_144773 ENSP00000217270 candidate 0 0 1 Metazoans 0 1 Signal transduction -1 chr20 5282689 5295015 WES head and neck squamous cell carcinoma PROM1 8842 prominin 1 4p15.32 5079 9454 604365 "NP_006008;NP_001139321;NP_001139320;NP_001139323;NP_001139319;NP_001139322;NP_001139324" "NM_006017;NM_001145849;NM_001145848;NM_001145851;NM_001145847;NM_001145850;NM_001145852" "ENSP00000427346;ENSP00000426090;ENSP00000438045;ENSP00000443620;ENSP00000415481" candidate 0 0 0 Metazoans 5 1 Cell response to stimuli 64 chr4 15981020 16077529 WES chronic lymphocytic leukemia PROSER1 80209 proline and serine rich 1 13q13.3 12616 20291 - "NP_733837;NP_079414" "NM_170719;NM_025138" ENSP00000332034 candidate 0 0 0 Last Universal Common Ancestor 2 5 -1 64 chr13 39585505 39611379 WGS chronic lymphocytic leukemia PRPF4B 8899 PRP4 pre-mRNA processing factor 4 homolog B (yeast) 6p25.2 9087 17346 602338 NP_003904 "NM_176800;NM_003913" ENSP00000433547 candidate 0 0 1 Last Universal Common Ancestor 27 1 Cellular metabolism,Cellular processes,DNA/RNA metabolism and transcription,Regulation of transcription 93 chr6 4031794 4060847 WES breast PRPF8 10594 PRP8 pre-mRNA processing factor 8 homolog (S. cerevisiae) 17p13.3 6295 17340 607300 NP_006436 NM_006445 ENSP00000304350 candidate 0 0 0 Eukaryotes 26 0 Cell response to stimuli,DNA/RNA metabolism and transcription,Regulation of transcription 109 chr17 1554099 1587865 WGS lung PRPS1 5631 phosphoribosyl pyrophosphate synthetase 1 Xq21.32-q24 2413 9462 311850 "NP_001191331;NP_002755" "NM_001204402;NM_002764" ENSP00000361512 candidate 0 0 3 Last Universal Common Ancestor 13 5 Cell response to stimuli,Cellular metabolism,DNA/RNA metabolism and transcription,Development 107 chrX 106871859 106893259 WES breast PRRC2A 7916 proline-rich coiled-coil 2A 6p21.3 807 13918 142580 "NP_542417;NP_004629" "NM_080686;NM_004638" "ENSP00000365201;ENSP00000365175" candidate 0 0 0 Opisthokonts 55 1 -1 101 chr6 31590567 31605360 WES breast PRRX1 5396 paired related homeobox 1 1q24 1337 9142 167420 "NP_008833;NP_073207" "NM_006902;NM_022716" ENSP00000239461 known 1 0 0 Eukaryotes 5 3 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription 88 chr1 170633360 170705324 CGC leukemia PRUNE2 158471 prune homolog 2 (Drosophila) 9q21.2 12970 25209 610691 NP_056040 "NM_015225;NM_138818" ENSP00000365908 candidate 0 0 0 Eukaryotes 4 6 Cell cycle,Development,Regulation of intracellular processes and metabolism 91 chr9 79234258 79520879 WES colorectal PSIP1 11168 PC4 and SFRS1 interacting protein 1 9p22.3 4688 9527 603620 "NP_150091;NP_066967;NP_001121689" "NM_033222;NM_021144;NM_001128217" "ENSP00000370114;ENSP00000380653;ENSP00000370109" known 1 0 0 Eukaryotes 23 5 Cellular metabolism,DNA/RNA metabolism and transcription,Multicellular activities,Other,Regulation of intracellular processes and metabolism,Regulation of transcription 96 chr9 15465521 15510186 CGC leukemia PSTK 118672 phosphoseryl-tRNA kinase 10q26.13 16586 28578 611310 NP_699167 NM_153336 ENSP00000357882 candidate 0 0 0 Last Universal Common Ancestor 1 0 Cellular metabolism,Regulation of intracellular processes and metabolism,Regulation of transcription -1 chr10 124739996 124746480 WGS liver PTCH1 5727 patched 1 9q22.3 3200 9585 601309 "NP_001077071;NP_001077073;NP_001077072;NP_000255;NP_001077074;NP_001077076;NP_001077075" "NM_001083602;NM_001083604;NM_001083603;NM_000264;NM_001083605;NM_001083607;NM_001083606" "ENSP00000332353;ENSP00000389744;ENSP00000399981;ENSP00000414823;ENSP00000396135" known 0 1 0 Eukaryotes 11 0 Cell cycle,Cellular metabolism,Cellular processes,Development,Regulation of intracellular processes and metabolism,Signal transduction 78 chr9 98209197 98270643 CGC,WES,WGS medulloblastoma,skin PTCH2 8643 patched 2 1p34.1 4722 9586 603673 "NP_003729;NP_001159764" "NM_003738;NM_001166292" "ENSP00000389703;ENSP00000361266" candidate 0 0 0 Eukaryotes 7 0 Development,Multicellular activities 22 chr1 45288090 45308604 WGS breast PTCHD3 374308 patched domain containing 3 10p12.1 - 24776 611791 NP_001030014 NM_001034842 ENSP00000417658 candidate 0 0 0 Eukaryotes 3 2 -1 -1 chr10 27687226 27703179 WGS glioblastoma PTEN 5728 phosphatase and tensin homolog 10q23.3 3431 9588 601728 NP_000305 NM_000314 - known 0 1 1 Last Universal Common Ancestor 98 22 Cell cycle,Cell motility and interactions,Cellular metabolism,Cellular processes,Development,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction 99 chr10 89624227 89725226 CGC,HTMS,WES,WGS endometrium,glioma,prostate,breast,glioblastoma,lung,ovarian,pancreas,sarcoma,cholangiocarcinoma,colorectal,gastric,head and neck squamous cell carcinoma,medulloblastoma PTGFR 5737 prostaglandin F receptor (FP) 1p31.1 8988 9600 600563 "NP_000950;NP_001034674" "NM_000959;NM_001039585" "ENSP00000359793;ENSP00000359792" candidate 0 0 0 Metazoans 1 1 Signal transduction 4 chr1 78958429 79002369 HTMS breast,lung,ovarian,pancreas,prostate PTK2B 2185 PTK2B protein tyrosine kinase 2 beta 8p21.1 3131 9612 601212 "NP_775268;NP_775267;NP_004094;NP_775266" "NM_173176;NM_173175;NM_004103;NM_173174" "ENSP00000380638;ENSP00000391995;ENSP00000332816" candidate 0 0 0 Last Universal Common Ancestor 97 2 Cell cycle,Cellular metabolism,Cellular processes,Regulation of intracellular processes and metabolism,Signal transduction 64 chr8 27255102 27316023 HTMS sarcoma PTK6 5753 PTK6 protein tyrosine kinase 6 20q13.3 3594 9617 602004 "NP_001243287;NP_005966" "NM_001256358;NM_005975" ENSP00000217185 known 0 0 0 Last Universal Common Ancestor 5 0 Cellular metabolism,Cellular processes 5 chr20 62160892 62168667 CGC,Amplified PTMS 5763 parathymosin 12p13 1344 9629 168440 NP_002815 NM_002824 ENSP00000310088 candidate 0 0 0 Vertebrates 21 4 Cellular metabolism,DNA/RNA metabolism and transcription 38 chr12 6875872 6879605 WGS liver PTN 5764 pleiotrophin 7q33 1199 9630 162095 NP_002816 NM_002825 ENSP00000341170 candidate 0 0 0 Metazoans 162 0 Cell cycle,Development,Multicellular activities,Regulation of intracellular processes and metabolism,Signal transduction 94 chr7 136935978 136939720 WES gastric PTPN11 5781 protein tyrosine phosphatase, non-receptor type 11 12q24 1470 9644 176876 NP_002825 NM_002834 "ENSP00000340944;ENSP00000376376" known 1 0 5 Eukaryotes 46 7 Cell response to stimuli,Cellular metabolism,Cellular processes,Signal transduction 101 chr12 112884078 112942565 CGC leukemia,myelodysplasia PTPN12 5782 protein tyrosine phosphatase, non-receptor type 12 7q11.23 2513 9645 600079 "NP_001124481;NP_002826;NP_001124480" "NM_001131009;NM_002835;NM_001131008" "ENSP00000397991;ENSP00000248594" candidate 0 0 0 Eukaryotes 46 7 Cellular metabolism,Cellular processes 82 chr7 77166864 77268594 WES colorectal (hypermutated) PTPN22 26191 protein tyrosine phosphatase, non-receptor type 22 (lymphoid) 1p13.2 6100 9652 600716 "NP_001180360;NP_057051;NP_036543" "NM_001193431;NM_015967;NM_012411" "ENSP00000435176;ENSP00000352833" candidate 0 0 0 Eukaryotes 22 2 Cellular metabolism,Cellular processes,Signal transduction 19 chr1 114357530 114414245 WES breast PTPRD 5789 protein tyrosine phosphatase, receptor type, D 9p23-p24.3 3358 9668 601598 "NP_569076;NP_569077;NP_001035802;NP_002830;NP_569075;NP_001164496" "NM_130392;NM_130393;NM_001040712;NM_002839;NM_130391;NM_001171025" "ENSP00000380735;ENSP00000380741;ENSP00000370593;ENSP00000347373" candidate 0 0 0 Eukaryotes 3 7 Cellular metabolism,Cellular processes,Signal transduction 68 chr9 8317877 8733843 HTMS,WES lung,breast,colorectal,pancreas PTPRJ 5795 protein tyrosine phosphatase, receptor type, J 11p11.2 2955 9673 600925 "NP_002834;NP_001091973" "NM_002843;NM_001098503" ENSP00000409733 candidate 0 0 0 Eukaryotes 37 8 Cellular metabolism,Cellular processes,Signal transduction 52 chr11 48002465 48188911 WGS breast PTPRO 5800 protein tyrosine phosphatase, receptor type, O 12p13.3-p13.2|12p13-p12 2784 9678 600579 "NP_109593;NP_002839;NP_109594;NP_109596;NP_109592;NP_109595" "NM_030668;NM_002848;NM_030669;NM_030671;NM_030667;NM_030670" "ENSP00000343434;ENSP00000281171;ENSP00000439234;ENSP00000393449" candidate 0 0 0 Eukaryotes 25 2 Cellular metabolism,Cellular processes 109 chr12 15475661 15747972 WES melanoma PTPRS 5802 protein tyrosine phosphatase, receptor type, S 19p13.3 3344 9681 601576 "NP_570925;NP_002841;NP_570923;NP_570924" "NM_130855;NM_002850;NM_130853;NM_130854" "ENSP00000349932;ENSP00000327313;ENSP00000269907" candidate 0 0 0 Eukaryotes 23 0 Cellular metabolism,Cellular processes 9 chr19 5206788 5286151 WES colorectal PTPRT 11122 protein tyrosine phosphatase, receptor type, T 20q12-q13 6690 9682 608712 "NP_008981;NP_573400" "NM_007050;NM_133170" "ENSP00000362283;ENSP00000362294" candidate 0 0 0 Eukaryotes 19 1 Cellular metabolism,Cellular processes,Signal transduction 31 chr20 40709522 41818373 WGS acute myeloid leukemia PTPRU 10076 protein tyrosine phosphatase, receptor type, U 1p35.3 3908 9683 602454 "NP_573439;NP_001181930;NP_573438;NP_005695" "NM_133178;NM_001195001;NM_133177;NM_005704" "ENSP00000392332;ENSP00000432906;ENSP00000362884" candidate 0 0 0 Eukaryotes 7 1 Cellular metabolism,Cellular processes,Signal transduction 52 chr1 29563157 29652170 WES colorectal PTRF 284119 polymerase I and transcript release factor 17q21.2 4433 9688 603198 NP_036364 NM_012232 ENSP00000349541 candidate 0 0 0 Vertebrates 47 3 Cellular metabolism,Cellular processes,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription 71 chr17 40556708 40575115 WGS melanoma PVRIG 79037 poliovirus receptor related immunoglobulin domain containing 7q22.1 - 32190 - NP_076975 NM_024070 ENSP00000316675 candidate 0 0 1 Mammals 0 0 -1 46 chr7 99817534 99818871 WES melanoma PXDN 7837 peroxidasin homolog (Drosophila) 2p25 - 14966 605158 NP_036425 NM_012293 ENSP00000252804 candidate 0 0 0 Last Universal Common Ancestor 1 8 Cell response to stimuli,Cellular metabolism 90 chr2 1637979 1748227 WES pancreas PXDNL 137902 peroxidasin homolog (Drosophila)-like 8q11.22-q11.23 8693 26359 - NP_653252 NM_144651 ENSP00000348645 candidate 0 0 0 Last Universal Common Ancestor 0 0 Cell response to stimuli,Cellular metabolism -1 chr8 52232454 52721904 WGS chronic lymphocytic leukemia QRICH2 84074 glutamine rich 2 17q25.1 10891 25326 - NP_115510 NM_032134 ENSP00000262765 candidate 0 0 0 Last Universal Common Ancestor 13 0 -1 -1 chr17 74271901 74301022 WGS lymphoma RAB23 51715 RAB23, member RAS oncogene family 6p11 5850 14263 606144 "NP_057361;NP_899050" "NM_016277;NM_183227" ENSP00000320413 known 0 0 0 Last Universal Common Ancestor 3 9 Cellular metabolism,Cellular processes,Development,Regulation of intracellular processes and metabolism,Signal transduction 8 chr6 57055262 57075178 CGC,Amplified RAB24 53917 RAB24, member RAS oncogene family 5q35.3 6697 9765 612415 "NP_570137;NP_001026847" "NM_130781;NM_001031677" "ENSP00000304376;ENSP00000377235" candidate 0 0 0 Last Universal Common Ancestor 23 0 Cellular processes,Signal transduction -1 chr5 176728747 176730289 WGS lymphoma RAB25 57111 RAB25, member RAS oncogene family 1q22 6698 18238 612942 NP_065120 NM_020387 ENSP00000354376 known 0 0 0 Last Universal Common Ancestor 18 0 Cellular processes,Signal transduction 42 chr1 156035701 156040075 CGC,Amplified RABEP1 9135 rabaptin, RAB GTPase binding effector protein 1 17p13.2 4684 17677 603616 "NP_001077054;NP_004694" "NM_001083585;NM_004703" "ENSP00000386150;ENSP00000262477" known 1 0 0 Metazoans 39 1 Cell cycle,Cellular processes 35 chr17 5211982 5286515 CGC leukemia RAD51B 5890 RAD51 homolog B (S. cerevisiae) 14q23-q24.2 4255 9822 602948 "NP_002868;NP_598193;NP_598194" "NM_002877;NM_133509;NM_133510" "ENSP00000419471;ENSP00000418859" known 1 0 0 Last Universal Common Ancestor 5 0 Cell cycle,DNA/RNA metabolism and transcription 29 chr14 68290261 68934966 CGC lipoma,uterus RAD54L2 23132 RAD54-like 2 (S. cerevisiae) 3p21.2 10018 29123 - NP_055921 NM_015106 ENSP00000386520 candidate 0 0 0 Last Universal Common Ancestor 36 1 -1 1 chr3 51624437 51697433 WGS melanoma RADIL 55698 Ras association and DIL domains 7p22.1 7663 22226 611491 NP_060529 NM_018059 ENSP00000382492 candidate 0 0 0 Eukaryotes 31 2 Signal transduction -1 chr7 4839012 4917770 WES cholangiocarcinoma RAF1 5894 v-raf-1 murine leukemia viral oncogene homolog 1 3p25 1265 9829 164760 NP_002871 NM_002880 ENSP00000251849 known 1 0 0 Last Universal Common Ancestor 54 5 Cell cycle,Cellular metabolism,Cellular processes,Signal transduction 106 chr3 12626016 12660220 CGC,WGS pilocytic astrocytoma,liver RALGDS 5900 ral guanine nucleotide dissociation stimulator 9q34.3 3371 9842 601619 "NP_006257;NP_001035827" "NM_006266;NM_001042368" "ENSP00000376867;ENSP00000361120" known 1 0 0 Metazoans 24 1 Signal transduction 100 chr9 135973977 135996541 CGC lymphoma RANBP17 64901 RAN binding protein 17 5q34 5847 14428 606141 NP_075048 NM_022897 ENSP00000427975 known 1 0 0 Eukaryotes 6 0 Cellular processes,DNA/RNA metabolism and transcription 25 chr5 170305101 170725859 CGC leukemia RANBP6 26953 RAN binding protein 6 9p24.1 17953 9851 - "NP_001230131;NP_001230132;NP_036548" "NR_024094;NR_024095;NM_001243202;NM_001243203;NM_012416" ENSP00000259569 candidate 0 0 1 Eukaryotes 6 2 Cellular processes 61 chr9 6012293 6015607 WES lymphoma RAP1GDS1 5910 RAP1, GTP-GDP dissociation stimulator 1 4q23-q25 11763 9859 179502 "NP_001093900;NP_001093896;NP_001093899;NP_001093898;NP_001093897;NP_066982" "NM_001100430;NM_001100426;NM_001100429;NM_001100428;NM_001100427;NM_021159" ENSP00000386153 known 1 0 0 Eukaryotes 5 0 -1 72 chr4 99214555 99363265 CGC leukemia RAPH1 65059 Ras association (RalGDS/AF-6) and pleckstrin homology domains 1 2q33 12356 14436 609035 "NP_976241;NP_998754" "NM_025252;NM_203365;NM_213589" "ENSP00000311293;ENSP00000316543" candidate 0 0 0 Eukaryotes 7 3 Signal transduction -1 chr2 204304163 204360076 WES breast RARA 5914 retinoic acid receptor, alpha 17q21 6769 9864 180240 "NP_001138773;NP_000955;NP_001019980;NP_001138774" "NM_001033603;NM_001145301;NM_000964;NM_001024809;NM_001145302" - known 1 0 1 Metazoans 63 3 Cell response to stimuli,Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction 64 chr17 38487471 38512475 CGC leukemia RASA1 5921 RAS p21 protein activator (GTPase activating protein) 1 5q13.3 745 9871 139150 "NP_002881;NP_072179" "NM_002890;NM_022650" ENSP00000411221 candidate 0 0 0 Eukaryotes 29 5 Cell cycle,Cell motility and interactions,Cellular metabolism,Cellular processes,DNA/RNA metabolism and transcription,Development,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction 104 chr5 86564269 86686697 WES head and neck squamous cell carcinoma RASAL2 9462 RAS protein activator like 2 1q24 5845 9874 606136 "NP_004832;NP_733793" "NM_004841;NM_170692" "ENSP00000420558;ENSP00000407768" candidate 0 0 0 Eukaryotes 6 2 Signal transduction 18 chr1 178063628 178442371 WES breast RASEF 158158 RAS and EF-hand domain containing 9q21.32 8337 26464 611344 NP_689786 NM_152573 - candidate 0 0 0 Last Universal Common Ancestor 1 1 Cellular processes,Signal transduction -1 chr9 85597595 85677782 WGS breast RASGEF1A 221002 RasGEF domain family, member 1A 10q11.21 15211 24246 - NP_660356 NM_145313 ENSP00000379155 candidate 0 0 0 Eukaryotes 1 1 Signal transduction -1 chr10 43691923 43701564 WES lymphoma RASGRF2 5924 Ras protein-specific guanine nucleotide-releasing factor 2 5q13 7588 9876 606614 NP_008840 NM_006909 ENSP00000265080 candidate 0 0 0 Eukaryotes 2 0 Signal transduction -1 chr5 80256558 80521586 WES colorectal RASSF6 166824 Ras association (RalGDS/AF-6) domain family member 6 4q13.3 15220 20796 612620 "NP_803876;NP_958834" "NM_177532;NM_201431" ENSP00000303877 candidate 0 0 0 Eukaryotes 6 6 Signal transduction -1 chr4 74441955 74486217 WES,WGS pancreas,chronic lymphocytic leukemia RASSF8 11228 Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 12p12.3 7084 13232 608231 "NP_001158219;NP_001158220;NP_001158218;NP_009142" "NM_001164747;NM_001164748;NM_001164746;NM_007211" "ENSP00000443096;ENSP00000384491;ENSP00000370756" candidate 0 0 0 Opisthokonts 5 8 Signal transduction 10 chr12 26208277 26221748 WES lung RB1 5925 retinoblastoma 1 13q14.2 1574 9884 614041 NP_000312 NM_000321 ENSP00000267163 known 0 1 0 Eukaryotes 202 16 Cell cycle,Cellular metabolism,DNA/RNA metabolism and transcription,Development,Multicellular activities,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction 65 chr13 48878049 49054204 CGC,HTMS,WES,WGS breast,lung,retinoblastoma,sarcoma,glioblastoma,bladder,prostate RBBP9 10741 retinoblastoma binding protein 9 20p11.2 4217 9892 602908 NP_006597 "NM_006606;NM_153328" ENSP00000336866 candidate 0 0 0 Last Universal Common Ancestor 7 3 -1 18 chr20 18470411 18477811 WGS chronic lymphocytic leukemia RBFOX1 54715 RNA binding protein, fox-1 homolog (C. elegans) 1 16p13.3 16091 18222 605104 "NP_001135806;NP_665898;NP_665900;NP_061193;NP_001135805;NP_665899" "NM_001142334;NM_145891;NM_145893;NM_018723;NM_001142333;NM_145892" ENSP00000344196 candidate 0 0 0 Eukaryotes 45 2 Cellular processes,DNA/RNA metabolism and transcription,Regulation of transcription 48 chr16 7383003 7760744 WGS lymphoma RBM15 64783 RNA binding motif protein 15 1p13 5832 14959 606077 "NP_001188474;NP_073605" "NM_001201545;NM_022768" ENSP00000358799 known 1 0 1 Eukaryotes 18 0 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription 36 chr1 110882028 110888228 CGC leukemia RBM19 9904 RNA binding motif protein 19 12q24.21 15225 29098 - "NP_001140171;NP_057280;NP_001140170" "NM_001146699;NM_016196;NM_001146698" "ENSP00000376344;ENSP00000442053;ENSP00000261741" candidate 0 0 0 Last Universal Common Ancestor 1 3 -1 49 chr12 114261032 114400219 WGS liver RBM27 54439 RNA binding motif protein 27 5q32 - 29243 - NP_061862 NM_018989 ENSP00000265271 candidate 0 0 0 Eukaryotes 12 0 -1 -1 chr5 145583329 145665590 WES glioblastoma RBM47 54502 RNA binding motif protein 47 4p14 - 30358 - "NP_061900;NP_001092104" "NM_019027;NM_001098634" "ENSP00000371212;ENSP00000371214" candidate 0 0 0 Eukaryotes 3 6 -1 65 chr4 40427924 40440910 WGS breast,lymphoma RBMX2 51634 RNA binding motif protein, X-linked 2 Xq26.1 6470 24282 - NP_057108 NM_016024 ENSP00000339090 candidate 0 0 3 Last Universal Common Ancestor 5 0 -1 70 chrX 129536230 129546819 WGS breast REC8 9985 REC8 homolog (yeast) 14q11.2-q12 9739 16879 608193 "NP_001041670;NP_005123" "NM_001048205;NM_005132" "ENSP00000453242;ENSP00000308699" candidate 0 0 0 Last Universal Common Ancestor 4 0 Cell cycle,DNA/RNA metabolism and transcription,Development,Multicellular activities 86 chr14 24641762 24649298 WGS glioblastoma RECQL4 9401 RecQ protein-like 4 8q24.3 4805 9949 603780 NP_004251 NM_004260 - known 0 1 0 Last Universal Common Ancestor 13 1 Cell cycle,Cellular processes,DNA/RNA metabolism and transcription,Development,Regulation of intracellular processes and metabolism 2 chr8 145736817 145743168 CGC REL 5966 v-rel reticuloendotheliosis viral oncogene homolog (avian) 2p13-p12 1286 9954 164910 NP_002899 NM_002908 ENSP00000295025 known 1 0 0 Metazoans 70 1 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction 50 chr2 61118814 61149667 CGC,Amplified lymphoma RERGL 79785 RERG/RAS-like 12p12.3 8659 26213 - NP_079006 NM_024730 ENSP00000229002 candidate 0 0 0 Last Universal Common Ancestor 0 1 Signal transduction 5 chr12 18234128 18242217 WGS chronic lymphocytic leukemia REST 5978 RE1-silencing transcription factor 4q12 8990 9966 600571 "NP_005603;NP_001180437" "NM_005612;NM_001193508" ENSP00000311816 candidate 0 0 0 Eukaryotes 31 5 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription 28 chr4 57776805 57798315 WGS melanoma RET 5979 ret proto-oncogene 10q11.2 1266 9967 164761 "NP_066124;NP_065681" "NM_020975;NM_000323;NM_020629;NM_020630" "ENSP00000344798;ENSP00000347942" known 1 0 0 Last Universal Common Ancestor 45 3 Cell motility and interactions,Cellular metabolism,Cellular processes,Development,Signal transduction 66 chr10 43595894 43623714 CGC,HTMS,WES lung,pheochromocytoma,thyroid,breast,ovarian,pancreas,prostate,colorectal,lymphoma RFC2 5982 replication factor C (activator 1) 2, 40kDa 7q11.23 2675 9970 600404 "NP_002905;NP_852136" "NM_002914;NM_181471" "ENSP00000275627;ENSP00000055077" candidate 0 0 1 Last Universal Common Ancestor 12 2 Cellular metabolism,DNA/RNA metabolism and transcription 44 chr7 73646439 73668713 WGS liver RFTN1 23180 raftlin, lipid raft linker 1 3p24.3 17950 30278 - NP_055965 NM_015150 ENSP00000334153 candidate 0 0 0 Metazoans 2 0 -1 98 chr3 16358338 16535376 WES chronic lymphocytic leukemia RFWD2 64326 ring finger and WD repeat domain 2 1q25.1-q25.2 7455 17440 608067 "NP_071902;NP_001001740" "NM_022457;NM_001001740" ENSP00000356641 candidate 0 0 1 Last Universal Common Ancestor 64 2 -1 -1 chr1 175916328 176176114 WGS prostate RFX2 5990 regulatory factor X, 2 (influences HLA class II expression) 19p13.3 824 9983 142765 "NP_000626;NP_602309" "NM_000635;NM_134433" ENSP00000306335 candidate 0 0 0 Eukaryotes 2 4 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription 12 chr19 5994849 6047507 WES breast RGAG1 57529 retrotransposon gag domain containing 1 Xq23 6600 29245 - NP_065820 NM_020769 ENSP00000419786 candidate 0 0 0 Last Universal Common Ancestor 1 0 -1 -1 chrX 109693846 109698546 WES lymphoma RGL1 23179 ral guanine nucleotide dissociation stimulator-like 1 1q25.3 12032 30281 605667 NP_055964 NM_015149 ENSP00000303192 candidate 0 0 0 Metazoans 3 0 Signal transduction 92 chr1 183711293 183895423 WES breast RGS12 6002 regulator of G-protein signaling 12 4p16.3 3943 9994 602512 "NP_937872;NP_937870;NP_002917" "NM_198229;NM_198230;NM_198430;NM_198587;NM_198227;NM_198432;NM_002926" "ENSP00000338509;ENSP00000342133;ENSP00000339381" candidate 0 0 0 Eukaryotes 9 0 Regulation of intracellular processes and metabolism,Signal transduction 64 chr4 3317898 3441408 WES lymphoma RHEBL1 121268 Ras homolog enriched in brain like 1 12q13.12 15245 21166 - NP_653194 NM_144593 ENSP00000301068 candidate 0 0 0 Last Universal Common Ancestor 13 3 Signal transduction -1 chr12 49458889 49463568 HTMS breast,lung,ovarian,pancreas,prostate RHOA 387 ras homolog gene family, member A 3p21.3 1323 667 165390 NP_001655 NM_001664 ENSP00000400175 candidate 0 0 3 Last Universal Common Ancestor 29 9 Cellular processes,Regulation of intracellular processes and metabolism,Signal transduction 109 chr3 49397645 49413022 WES,WGS lymphoma RHOB 388 ras homolog gene family, member B 2p24 1321 668 165370 NP_004031 NM_004040 ENSP00000272233 candidate 0 0 2 Last Universal Common Ancestor 21 5 Cell cycle,Cellular processes,Development,Regulation of intracellular processes and metabolism,Signal transduction 104 chr2 20647227 20647814 WGS melanoma RHOH 399 ras homolog gene family, member H 4p13 3616 686 602037 NP_004301 NM_004310 ENSP00000371219 known 1 0 0 Last Universal Common Ancestor 15 0 Cellular metabolism,DNA/RNA metabolism and transcription,Development,Immune system response,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction 32 chr4 40245007 40245579 CGC non-hodgkin lymphoma RIMBP2 23504 RIMS binding protein 2 12q24.33 17183 30339 611602 NP_056162 NM_015347 ENSP00000261655 candidate 0 0 0 Eukaryotes 3 0 -1 34 chr12 130884224 130963558 WES head and neck squamous cell carcinoma RIMS2 9699 regulating synaptic membrane exocytosis 2 8q22.3 9436 17283 606630 "NP_055492;NP_001093587" "NM_014677;NM_001100117" - candidate 0 0 0 Eukaryotes 18 2 Cellular processes 54 chr8 104513115 105264045 WES breast,chronic lymphocytic leukemia,head and neck squamous cell carcinoma,lung RIT2 6014 Ras-like without CAAX 2 18q12.3 15253 10017 609592 NP_002921 NM_002930 ENSP00000321805 candidate 0 0 0 Last Universal Common Ancestor 12 0 Multicellular activities,Signal transduction 29 chr18 40323461 40695484 WES gastric RMI2 116028 RMI2, RecQ mediated genome instability 2, homolog (S. cerevisiae) 16p13.13 14497 28349 612426 NP_689521 NM_152308 ENSP00000310356 known 1 0 0 Eukaryotes 6 0 -1 -1 chr16 11439329 11444644 CGC lymphoma RNASEH2A 10535 ribonuclease H2, subunit A 19p13.2 6914 18518 606034 NP_006388 NM_006397 ENSP00000221486 candidate 0 0 0 Last Universal Common Ancestor 0 0 Cellular metabolism,DNA/RNA metabolism and transcription 98 chr19 12917488 12924277 WGS breast RNF103 7844 ring finger protein 103 2p11.2 3939 12859 602507 "NP_001185881;NP_005658;NP_001185880" "NM_001198952;NM_005667;NM_001198951" ENSP00000237455 candidate 0 0 0 Eukaryotes 21 0 Development 92 chr2 86830969 86850009 WES chronic lymphocytic leukemia RNF183 138065 ring finger protein 183 9q32 10082 28721 - NP_659488 NM_145051 ENSP00000417176 candidate 0 0 0 Eukaryotes 7 1 -1 -1 chr9 116059889 116060464 WGS prostate RNF207 388591 ring finger protein 207 1p36.31 13536 32947 - NP_997279 "NM_173795;NM_207396" ENSP00000367173 candidate 0 0 0 Eukaryotes 0 0 -1 -1 chr1 6266596 6279464 WES pancreas RNF213 57674 ring finger protein 213 17q25.3 10716 14539 613768 "NP_001243000;NP_066005;NP_065965" "NM_001256071;NM_020954;NM_020914" "ENSP00000464087;ENSP00000324392" known 1 0 0 Eukaryotes 5 3 -1 -1 chr17 78237481 78367295 CGC lymphoma RNF219 79596 ring finger protein 219 13q31.1 12619 20308 - NP_078822 NM_024546 ENSP00000282003 candidate 0 0 0 Metazoans 10 5 -1 65 chr13 79189718 79233255 WES colorectal RNF220 55182 ring finger protein 220 1p34.1 13336 25552 - NP_060620 NM_018150 ENSP00000354872 candidate 0 0 0 Eukaryotes 10 0 -1 84 chr1 44877770 45116444 WGS breast RNF43 54894 ring finger protein 43 17q22 7896 18505 612482 NP_060233 NM_017763 ENSP00000462764 candidate 0 0 0 Eukaryotes 22 1 -1 40 chr17 56432307 56492938 WES cholangiocarcinoma ROBO1 6091 roundabout, axon guidance receptor, homolog 1 (Drosophila) 3p12 3890 10249 602430 "NP_598334;NP_002932;NP_001139317" "NM_133631;NM_002941;NM_001145845" "ENSP00000420321;ENSP00000406043" candidate 0 0 0 Last Universal Common Ancestor 17 1 Cell cycle,Cell motility and interactions,Development,Regulation of intracellular processes and metabolism 58 chr3 78649263 79639061 WES,WGS colorectal,chronic lymphocytic leukemia ROBO2 6092 roundabout, axon guidance receptor, homolog 2 (Drosophila) 3p12.3 - 10250 602431 "NP_001122401;NP_002933" "NM_001128929;NM_002942" "ENSP00000417335;ENSP00000417164" candidate 0 0 0 Last Universal Common Ancestor 30 1 Cell cycle,Cell motility and interactions,Development,Regulation of intracellular processes and metabolism -1 chr3 77147164 77694054 WES cholangiocarcinoma ROS1 6098 c-ros oncogene 1 , receptor tyrosine kinase 6q22 1295 10261 165020 NP_002935 NM_002944 ENSP00000357494 known 1 0 0 Last Universal Common Ancestor 9 1 Cellular metabolism,Cellular processes,Signal transduction 49 chr6 117609658 117746819 CGC,HTMS,WES glioblastoma,lung,breast,ovarian,pancreas,prostate,chronic lymphocytic leukemia RP1 6101 retinitis pigmentosa 1 (autosomal dominant) 8q12.1 4896 10263 603937 NP_006260 NM_006269 ENSP00000220676 candidate 0 0 0 Last Universal Common Ancestor 1 1 Cell response to stimuli,Signal transduction -1 chr8 55533527 55542910 WGS breast,melanoma RP1L1 94137 retinitis pigmentosa 1-like 1 8p23.1 10546 15946 608581 NP_849188 NM_178857 ENSP00000371923 candidate 0 0 0 Eukaryotes 4 1 Cell response to stimuli,Signal transduction -1 chr8 10464408 10480711 WES breast RPGR 6103 retinitis pigmentosa GTPase regulator Xp21.1 2425 10295 312610 "NP_000319;NP_001030025" "NM_000328;NM_001023582;NM_001034853" "ENSP00000322219;ENSP00000367766" candidate 0 0 0 Last Universal Common Ancestor 15 1 Cell response to stimuli,Cellular processes 41 chrX 38144796 38182778 WES breast RPGRIP1 57096 retinitis pigmentosa GTPase regulator interacting protein 1 14q11 5673 13436 605446 NP_065099 NM_020366 ENSP00000382895 candidate 0 0 0 Eukaryotes 4 1 Cell response to stimuli 82 chr14 21756136 21819372 WES breast RPL13AP25 100287887 ribosomal protein L13a pseudogene 25 13q14.3 - 36981 - - - - candidate 0 0 -1 Last Universal Common Ancestor 0 0 Cellular metabolism,Regulation of transcription -1 - 0 0 WES pancreas RPL22 6146 ribosomal protein L22 1p36.31 1602 10315 180474 NP_000974 NM_000983 ENSP00000346088 known 1 0 17 Eukaryotes 89 0 Cellular metabolism,Regulation of transcription 109 chr1 6246735 6257816 CGC,WES leukemia,gastric RPN1 6184 ribophorin I 3q21.3 1598 10381 180470 NP_002941 NM_002950 ENSP00000296255 known 1 0 0 Eukaryotes 22 2 Cellular metabolism,Cellular processes 104 chr3 128339257 128369643 CGC leukemia RPS6KA2 6196 ribosomal protein S6 kinase, 90kDa, polypeptide 2 6q27 3403 10431 601685 "NP_066958;NP_001006933" "NM_021135;NM_001006932" "ENSP00000422435;ENSP00000265678" candidate 0 0 2 Last Universal Common Ancestor 22 1 Cellular metabolism,Cellular processes,Signal transduction 95 chr6 166826253 167275658 WGS melanoma RPS6KA3 6197 ribosomal protein S6 kinase, 90kDa, polypeptide 3 Xp22.2-p22.1 2092 10432 300075 NP_004577 NM_004586 ENSP00000368884 candidate 0 0 2 Last Universal Common Ancestor 45 3 Cellular metabolism,Cellular processes,Development,Signal transduction 72 chrX 20173519 20284750 WES liver RPS6KB1 6198 ribosomal protein S6 kinase, 70kDa, polypeptide 1 17q23.1 10202 10436 608938 NP_003152 NM_003161 ENSP00000225577 known 0 0 1 Last Universal Common Ancestor 78 7 Cellular metabolism,Cellular processes,Signal transduction 45 chr17 57970546 58024146 CGC,Amplified RRP8 23378 ribosomal RNA processing 8, methyltransferase, homolog (yeast) 11p15.4 13800 29030 - NP_056139 NM_015324 - candidate 0 0 0 Last Universal Common Ancestor 8 1 -1 44 chr11 6621379 6624732 WES acute myeloid leukemia RTTN 25914 rotatin 18q22.2 11525 18654 610436 NP_775901 NM_173630 ENSP00000255674 candidate 0 0 0 Eukaryotes 1 0 -1 -1 chr18 67671390 67872552 WES chronic lymphocytic leukemia RUFY1 80230 RUN and FYVE domain containing 1 5q35.3 15282 19760 610327 "NP_001035541;NP_079434;NP_001035542" "NM_001040451;NM_025158;NM_001040452" "ENSP00000390025;ENSP00000377087;ENSP00000325594" candidate 0 0 0 Eukaryotes 16 0 Cellular processes 107 chr5 178977571 179036517 WES head and neck squamous cell carcinoma RUNX1 861 runt-related transcription factor 1 21q22.3 1043 10471 151385 "NP_001001890;NP_001745;NP_001116079" "NM_001001890;NM_001754;NM_001122607" "ENSP00000340690;ENSP00000351123;ENSP00000409227" known 1 0 0 Metazoans 81 3 Cellular metabolism,DNA/RNA metabolism and transcription,Development,Regulation of intracellular processes and metabolism,Regulation of transcription 66 chr21 36164435 36421196 CGC,WES leukemia,acute myeloid leukemia,breast,myelodysplasia RUNX1T1 862 "runt-related transcription factor 1; translocated to, 1 (cyclin D-related)" 8q22 590 1535 133435 "NP_783554;NP_001185559;NP_001185608;NP_001185561;NP_001185562;NP_001185560;NP_001185558;NP_001185563;NP_783552;NP_001185554;NP_001185555;NP_783553;NP_001185556;NP_001185557;NP_004340" "NM_175636;NM_001198630;NM_001198679;NM_001198632;NM_001198633;NM_001198631;NM_001198629;NM_001198634;NM_175634;NM_001198625;NM_001198626;NM_175635;NM_001198627;NM_001198628;NM_004349" ENSP00000428543 known 1 0 0 Opisthokonts 60 5 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription 87 chr8 92972473 93107695 CGC,HTMS,WES leukemia,breast,lung,ovarian,pancreas,prostate,acute myeloid leukemia,colorectal RUVBL1 8607 RuvB-like 1 (E. coli) 3q21 9143 10474 603449 NP_003698 NM_003707 ENSP00000318297 known 0 0 0 Last Universal Common Ancestor 185 1 Cell cycle,Cellular metabolism,DNA/RNA metabolism and transcription,Development,Multicellular activities,Regulation of intracellular processes and metabolism,Regulation of transcription 29 chr3 127800096 127842567 CGC,Amplified RXFP3 51289 relaxin/insulin-like family peptide receptor 3 5p15.1-p14 17979 24883 609445 NP_057652 NM_016568 ENSP00000328708 candidate 0 0 0 Metazoans 2 2 Regulation of intracellular processes and metabolism,Signal transduction 1 chr5 33936846 33938252 WES head and neck squamous cell carcinoma RYR1 6261 ryanodine receptor 1 (skeletal) 19q13.1 1618 10483 180901 "NP_001036188;NP_000531" "NM_001042723;NM_000540" "ENSP00000352608;ENSP00000347667" candidate 0 0 0 Last Universal Common Ancestor 22 0 Cellular processes,Multicellular activities,Regulation of intracellular processes and metabolism 41 chr19 38924470 39078057 WES acute myeloid leukemia,kidney RYR2 6262 ryanodine receptor 2 (cardiac) 1q43 1619 10484 180902 NP_001026 NM_001035 ENSP00000355533 candidate 0 0 0 Last Universal Common Ancestor 30 1 Cell cycle,Cellular processes,Development,Multicellular activities,Regulation of intracellular processes and metabolism,Signal transduction 25 chr1 237205822 237995944 WES breast,chronic lymphocytic leukemia RYR3 6263 ryanodine receptor 3 15q14-q15 1620 10485 180903 "NP_001027;NP_001230925" "NM_001036;NM_001243996" "ENSP00000373884;ENSP00000399610" candidate 0 0 0 Last Universal Common Ancestor 7 4 Cellular processes,Regulation of intracellular processes and metabolism 66 chr15 33603247 34157424 WGS lung S1PR2 9294 sphingosine-1-phosphate receptor 2 19p13.2 5488 3169 605111 NP_004221 NM_004230 - candidate 0 0 0 Vertebrates 12 0 Cell cycle,Cellular metabolism,Cellular processes,Regulation of intracellular processes and metabolism,Signal transduction 1 chr19 10334523 10335581 WES lymphoma SAGE1 55511 sarcoma antigen 1 Xq26 2290 30369 300359 NP_061136 NM_018666 ENSP00000445959 candidate 0 0 1 Eukaryotes 0 0 -1 4 chrX 134978402 134995053 WES pancreas SALL3 27164 sal-like 3 (Drosophila) 18q23 5467 10527 605079 NP_741996 NM_171999 - candidate 0 0 0 Opisthokonts 21 0 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription -1 chr18 76740275 76757319 WES lymphoma SAMD9L 219285 sterile alpha motif domain containing 9-like 7q21.2 10798 1349 611170 NP_689916 NM_152703 ENSP00000326247 candidate 0 0 0 Last Universal Common Ancestor 2 1 -1 -1 chr7 92760533 92765284 WES liver SARDH 1757 sarcosine dehydrogenase 9q33-q34 6831 10536 604455 "NP_009032;NP_001128179" "NM_007101;NM_001134707" "ENSP00000403084;ENSP00000360938" candidate 0 0 0 Last Universal Common Ancestor 2 0 Cellular metabolism 38 chr9 136529014 136599295 WES acute myeloid leukemia SATB2 23314 SATB homeobox 2 2q33 12178 21637 608148 "NP_001165988;NP_056080;NP_001165980" "NM_001172517;NM_015265;NM_001172509" "ENSP00000401112;ENSP00000260926" candidate 0 0 0 Metazoans 6 2 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription 26 chr2 200136937 200320760 WES lung SAV1 60485 salvador homolog 1 (Drosophila) 14q13-q23 6229 17795 607203 NP_068590 NM_021818 ENSP00000324729 candidate 0 0 0 Eukaryotes 14 4 Signal transduction 56 chr14 51101904 51134685 HTMS breast,lung,ovarian,pancreas,prostate SBDS 51119 Shwachman-Bodian-Diamond syndrome 7q11.21 7393 19440 607444 NP_057122 NM_016038 ENSP00000246868 known 0 1 1 Last Universal Common Ancestor 33 1 Cell cycle,Cell motility and interactions,Cellular metabolism,Cellular processes,DNA/RNA metabolism and transcription,Development,Immune system response,Multicellular activities,Regulation of intracellular processes and metabolism,Regulation of transcription -1 chr7 66453361 66460404 CGC SCAF1 58506 SR-related CTD-associated factor 1 19q13.3-q13.4 11604 30403 - NP_067051 NM_021228 ENSP00000353769 candidate 0 0 0 Eukaryotes 6 3 DNA/RNA metabolism and transcription,Regulation of transcription -1 chr19 50148284 50161653 WGS melanoma SCAPER 49855 S-phase cyclin A-associated protein in the ER 15q24 11704 13081 611611 "NP_065894;NP_001139395" "NM_020843;NM_001145923" "ENSP00000442190;ENSP00000326924" candidate 0 0 0 Eukaryotes 7 0 -1 91 chr15 76640977 77154874 WGS lung SCEL 8796 sciellin 13q22 9161 10573 604112 "NP_001154178;NP_003834;NP_659001" "NM_001160706;NM_003843;NM_144777" "ENSP00000437895;ENSP00000366454" candidate 0 0 0 Eukaryotes 5 0 Development 6 chr13 78130011 78216948 WGS breast SCLT1 132320 sodium channel and clathrin linker 1 4q28.2 8700 26406 611399 NP_653244 NM_144643 ENSP00000281142 candidate 0 0 0 Eukaryotes 2 0 -1 -1 chr4 129805635 130003526 WGS chronic lymphocytic leukemia SCN11A 11280 sodium channel, voltage-gated, type XI, alpha subunit 3p22.2 5090 10583 604385 NP_054858 NM_014139 ENSP00000307599 candidate 0 0 0 Last Universal Common Ancestor 0 0 Cellular processes 58 chr3 38888188 38991853 WES,WGS prostate,chronic lymphocytic leukemia SCN3A 6328 sodium channel, voltage-gated, type III, alpha subunit 2q24 1671 10590 182391 "NP_001075146;NP_001075145;NP_008853" "NM_001081677;NM_001081676;NM_006922" "ENSP00000353206;ENSP00000283254" candidate 0 0 4 Last Universal Common Ancestor 3 6 Cellular processes 25 chr2 165946663 166032904 WGS melanoma SCN3B 55800 sodium channel, voltage-gated, type III, beta 11q23.3 10497 20665 608214 "NP_060870;NP_001035241" "NM_018400;NM_001040151" "ENSP00000299333;ENSP00000376523" candidate 0 0 0 Vertebrates 16 1 Cellular processes 49 chr11 123504854 123524509 WES colorectal SCN5A 6331 sodium channel, voltage-gated, type V, alpha subunit 3p21 2543 10593 600163 "NP_932173;NP_001092874;NP_001153632;NP_001092875;NP_001153633;NP_000326" "NM_198056;NM_001099404;NM_001160160;NM_001099405;NM_001160161;NM_000335" "ENSP00000397915;ENSP00000410257;ENSP00000416634;ENSP00000399524;ENSP00000388797;ENSP00000328968" candidate 0 0 0 Last Universal Common Ancestor 22 0 Cellular processes,Multicellular activities 18 chr3 38591815 38674798 WES pancreas SCN9A 6335 sodium channel, voltage-gated, type IX, alpha subunit 2q24 4565 10597 603415 NP_002968 NM_002977 ENSP00000386306 candidate 0 0 3 Last Universal Common Ancestor 0 1 Cellular processes 2 chr2 167055185 167168266 WES glioblastoma SCRT2 85508 scratch homolog 2, zinc finger protein (Drosophila) 20p13 15305 15952 - NP_149120 NM_033129 ENSP00000246104 candidate 0 0 0 Last Universal Common Ancestor 0 0 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription -1 chr20 644318 656245 WGS liver SDC4 6385 syndecan 4 20q12 8366 10661 600017 NP_002990 NM_002999 ENSP00000361818 known 1 0 0 Vertebrates 19 5 -1 94 chr20 43955907 43977024 CGC lung SDF4 51150 stromal cell derived factor 4 1p36.33 13113 24188 614282 "NP_057631;NP_057260" "NM_016547;NM_016176" "ENSP00000353094;ENSP00000263741" candidate 0 0 0 Eukaryotes 21 0 -1 109 chr1 1152895 1164173 WGS glioblastoma SDHAF2 54949 succinate dehydrogenase complex assembly factor 2 11q12.2 7915 26034 613019 NP_060311 NM_017841 - known 0 1 0 Last Universal Common Ancestor 27 2 -1 -1 chr11 61205097 61213540 CGC SDHB 6390 succinate dehydrogenase complex, subunit B, iron sulfur (Ip) 1p36.1-p35 1707 10681 185470 NP_002991 NM_003000 ENSP00000364649 known 0 1 0 Last Universal Common Ancestor 54 1 Cellular metabolism 98 chr1 17345379 17380514 CGC SDHC 6391 succinate dehydrogenase complex, subunit C, integral membrane protein, 15kDa 1q23.3 3878 10682 602413 "NP_001030589;NP_001030588;NP_001030590;NP_002992" "NM_001035512;NM_001035511;NM_001035513;NM_003001" - known 0 1 8 Last Universal Common Ancestor 8 3 Cellular metabolism 109 chr1 161293402 161332220 CGC SDHD 6392 succinate dehydrogenase complex, subunit D, integral membrane protein 11q23 4069 10683 602690 NP_002993 NM_003002 ENSP00000364699 known 0 1 7 Eukaryotes 1 0 Cellular metabolism 102 chr11 111957632 111965691 CGC SEC14L3 266629 SEC14-like 3 (S. cerevisiae) 22q12.2 15311 18655 612824 NP_777635 NM_174975 "ENSP00000385004;ENSP00000383896;ENSP00000444691;ENSP00000215812" candidate 0 0 0 Eukaryotes 0 4 -1 1 chr22 30856011 30867945 WGS glioblastoma SEMA3D 223117 sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D 7q21.11 15321 10726 609907 NP_689967 NM_152754 ENSP00000284136 candidate 0 0 0 Eukaryotes 19 0 Development 6 chr7 84628759 84751207 WES colorectal SEMA3E 9723 sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E 7q21.11 11545 10727 608166 "NP_001171600;NP_036563" "NM_001178129;NM_012431" ENSP00000303212 candidate 0 0 0 Eukaryotes 1 0 Development 4 chr7 82996905 83277858 WES gastric SEMA5B 54437 sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5B 3q21.1 15322 10737 609298 "NP_001243276;NP_001026872;NP_001243277;NP_001243275" "NR_046079;NM_001256347;NM_001031702;NM_018987;NM_001256348;NM_001256346" "ENSP00000350215;ENSP00000389588" candidate 0 0 0 Eukaryotes 12 0 Development -1 chr3 122628993 122680110 WES breast,pancreas SEPHS1 22929 selenophosphate synthetase 1 10p14 2944 19685 600902 "NP_036379;NP_001182531;NP_001182533" "NM_012247;NM_001195602;NM_001195604" "ENSP00000367887;ENSP00000367893" candidate 0 0 4 Last Universal Common Ancestor 36 1 Cellular metabolism,Cellular processes 98 chr10 13361145 13386950 WGS chronic lymphocytic leukemia SEPHS2 22928 selenophosphate synthetase 2 16p11.2 12096 19686 606218 NP_036380 NM_012248 ENSP00000418669 candidate 0 0 1 Last Universal Common Ancestor 1 0 Cellular metabolism 102 chr16 30455705 30457048 WES breast SEPT5 5413 septin 5 22q11.21 4100 9164 602724 "NP_002679;NP_001009939" "NM_002688;NM_001009939" "ENSP00000394541;ENSP00000391311" known 1 0 0 Eukaryotes 10 0 Cellular processes,Multicellular activities,Regulation of intracellular processes and metabolism,Signal transduction 11 chr22 19702112 19710004 CGC leukemia SEPT6 23157 septin 6 Xq24 6716 15848 300683 "NP_665799;NP_665798;NP_055944;NP_665801" "NM_145800;NM_145799;NM_015129;NM_145802" "ENSP00000378108;ENSP00000353278" known 1 0 2 Eukaryotes 16 2 -1 96 chrX 118763283 118809631 CGC leukemia SEPT7P2 641977 septin 7 pseudogene 2 7p12.3 - 32339 611563 - NR_024271 - candidate 0 0 -1 Eukaryotes 0 0 -1 -1 - 0 0 WES breast SEPT9 10801 septin 9 17q25 10360 7323 604061 "NP_001106964;NP_001106967;NP_001106965;NP_001106968;NP_001106966;NP_001106963;NP_006631" "NM_001113492;NM_001113495;NM_001113493;NM_001113496;NM_001113494;NM_001113491;NM_006640" "ENSP00000391249;ENSP00000400181;ENSP00000405877;ENSP00000403194;ENSP00000415624;ENSP00000438089;ENSP00000329161" known 1 0 0 Eukaryotes 187 3 Cell cycle,Cellular metabolism,Regulation of intracellular processes and metabolism 105 chr17 75303222 75494737 CGC,HTMS leukemia,breast,lung,ovarian,pancreas,prostate SERPINA1 5265 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 14q32.1 2463 8941 107400 "NP_001121179;NP_001121172;NP_001121176;NP_001121177;NP_001002235;NP_000286;NP_001121174;NP_001002236;NP_001121178;NP_001121173;NP_001121175" "NM_001127707;NM_001127700;NM_001127704;NM_001127705;NM_001002235;NM_000295;NM_001127702;NM_001002236;NM_001127706;NM_001127701;NM_001127703" "ENSP00000390299;ENSP00000348068;ENSP00000416066;ENSP00000408474" candidate 0 0 0 Last Universal Common Ancestor 37 1 Cell response to stimuli,Immune system response,Multicellular activities 75 chr14 94844789 94849574 WES lymphoma SERPINA12 145264 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 12 14q32.13 18038 18359 - NP_776249 NM_173850 ENSP00000342109 candidate 0 0 0 Last Universal Common Ancestor 1 0 -1 -1 chr14 94953643 94964734 WES glioblastoma SERPINA6 866 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 6 14q32.1 419 1540 122500 NP_001747 NM_001756 ENSP00000342850 candidate 0 0 0 Last Universal Common Ancestor 0 0 -1 31 chr14 94770758 94780985 WGS melanoma SET 6418 SET nuclear oncogene 9q34 9023 10760 600960 "NP_003002;NP_001234929;NP_001116293;NP_001234930" "NM_003011;NM_001248000;NM_001122821;NM_001248001" "ENSP00000361777;ENSP00000318012" known 1 0 11 Eukaryotes 117 3 Cellular metabolism,Cellular processes,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism 109 chr3 155705093 155705962 CGC leukemia SETBP1 26040 SET binding protein 1 18q21.1 10224 15573 611060 "NP_001123582;NP_056374" "NM_001130110;NM_015559" "ENSP00000390687;ENSP00000282030" candidate 0 0 0 Eukaryotes 0 0 -1 60 chr18 42281312 42643660 WES leukemia SETD2 29072 SET domain containing 2 3p21.31 11043 18420 612778 NP_054878 "NM_012271;NM_014159" ENSP00000386759 known 0 1 0 Last Universal Common Ancestor 16 0 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription 99 chr3 47058586 47205414 CGC,HTMS,WES kidney,breast SETD5 55209 SET domain containing 5 3p25.3 - 25566 - NP_001073986 "NM_018187;NM_001080517" ENSP00000385852 candidate 0 0 0 Eukaryotes 6 1 -1 93 chr3 9470623 9517772 WGS chronic lymphocytic leukemia SF3B1 23451 splicing factor 3b, subunit 1, 155kDa 2q33.1 9281 10768 605590 "NP_001005526;NP_036565" "NM_001005526;NM_012433" "ENSP00000402997;ENSP00000335321" known 1 0 0 Eukaryotes 214 0 DNA/RNA metabolism and transcription,Development,Regulation of transcription 109 chr2 198257030 198288699 CGC,WES,WGS myelodysplastic syndrome,breast,chronic lymphocytic leukemia,pancreas,medulloblastoma SFPQ 6421 splicing factor proline/glutamine-rich 1p34.3 7284 10774 605199 NP_005057 NM_005066 ENSP00000349748 known 1 0 0 Metazoans 146 3 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription 107 chr1 35650060 35658650 CGC kidney SFXN4 119559 sideroflexin 4 10q26.11 18046 16088 - NP_998814 "NM_178867;NM_213649" ENSP00000347924 candidate 0 0 0 Eukaryotes 5 0 Cellular processes -1 chr10 120900757 120925159 WES pancreas SGK1 6446 serum/glucocorticoid regulated kinase 1 6q23 4264 10810 602958 "NP_005618;NP_001137150;NP_001137148;NP_001137149" "NM_005627;NM_001143678;NM_001143676;NM_001143677" "ENSP00000356832;ENSP00000396242;ENSP00000237305" candidate 0 0 0 Last Universal Common Ancestor 97 3 Cell cycle,Cellular metabolism,Cellular processes 95 chr6 134491409 134638598 WES lymphoma,non-hodgkin lymphoma SH3GL1 6455 SH3-domain GRB2-like 1 19p13.3 3462 10830 601768 "NP_001186872;NP_001186873;NP_003016" "NM_001199943;NM_001199944;NM_003025" "ENSP00000470792;ENSP00000269886" known 1 0 3 Eukaryotes 18 1 Cellular processes,Development,Signal transduction 30 chr19 4361600 4400365 CGC leukemia SH3TC1 54436 SH3 domain and tetratricopeptide repeats 1 4p16.1 11556 26009 - NP_061859 NM_018986 ENSP00000245105 candidate 0 0 0 Metazoans 17 0 -1 72 chr4 8206922 8242679 WES colorectal SHANK1 50944 SH3 and multiple ankyrin repeat domains 1 19q13.3 5413 15474 604999 NP_057232 NM_016148 ENSP00000293441 candidate 0 0 0 Last Universal Common Ancestor 20 1 Cellular processes 13 chr19 51165225 51220176 WES colorectal,kidney SHC1 6464 SHC (Src homology 2 domain containing) transforming protein 1 1q21 2780 10840 600560 "NP_001123513;NP_001123512;NP_003020;NP_892113;NP_001189788" "NM_001130041;NM_001130040;NM_003029;NM_183001;NM_001202859" "ENSP00000401303;ENSP00000357435;ENSP00000357438;ENSP00000357430" known 0 0 1 Eukaryotes 295 8 Cell cycle,Cellular metabolism,Cellular processes,Regulation of intracellular processes and metabolism,Signal transduction 109 chr1 154936282 154943002 CGC,Amplified SHC3 53358 SHC (Src homology 2 domain containing) transforming protein 3 9q22.1 12005 18181 605263 NP_058544 NM_016848 - candidate 0 0 0 Eukaryotes 18 4 Development,Signal transduction 14 chr9 91628365 91793375 WGS lung SHE 126669 Src homology 2 domain containing E 1q21.3 17293 27004 610482 NP_001010846 NM_001010846 ENSP00000307369 candidate 0 0 0 Eukaryotes 2 5 -1 -1 chr1 154456628 154474502 WGS breast SHH 6469 sonic hedgehog 7q36 2838 10848 600725 NP_000184 NM_000193 - known 0 0 0 Eukaryotes 0 1 Cell cycle,Cell motility and interactions,Cell response to stimuli,Cellular metabolism,Cellular processes,DNA/RNA metabolism and transcription,Development,Immune system response,Multicellular activities,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction 7 chr7 155595597 155604816 CGC,Amplified SHKBP1 92799 SH3KBP1 binding protein 1 19q13.2 15338 19214 - NP_612401 NM_138392 ENSP00000291842 candidate 0 0 0 Eukaryotes 15 0 Cellular processes -1 chr19 41082806 41097110 WES acute myeloid leukemia SHROOM3 57619 shroom family member 3 4q21.1 7053 30422 604570 NP_065910 NM_020859 ENSP00000296043 candidate 0 0 0 Metazoans 5 1 Cellular processes,Development,Regulation of intracellular processes and metabolism -1 chr4 77357206 77700327 WES gastric SI 6476 sucrase-isomaltase (alpha-glucosidase) 3q25.2-q26.2 1962 10856 609845 NP_001032 NM_001041 ENSP00000264382 candidate 0 0 0 Last Universal Common Ancestor 1 1 -1 5 chr3 164697153 164793800 WES chronic lymphocytic leukemia,head and neck squamous cell carcinoma SIGLEC1 6614 sialic acid binding Ig-like lectin 1, sialoadhesin 20p13 2854 11127 600751 NP_075556 NM_023068 ENSP00000341141 candidate 0 0 0 Eukaryotes 3 0 Cell motility and interactions,Immune system response 89 chr20 3669210 3687775 WES pancreas SIGLEC10 89790 sialic acid binding Ig-like lectin 10 19q13.3 7307 15620 606091 "NP_001164628;NP_001164631;NP_001164632;NP_001164627;NP_001164629;NP_149121;NP_001164630" "NM_001171157;NM_001171160;NM_001171161;NM_001171156;NM_001171158;NM_033130;NM_001171159" "ENSP00000342389;ENSP00000408387;ENSP00000396742;ENSP00000395475;ENSP00000348646" candidate 0 0 1 Eukaryotes 3 1 -1 -1 chr19 51914356 51920835 WGS lymphoma SIK3 23387 SIK family kinase 3 11q23.3 11121 29165 - NP_079440 NM_025164 ENSP00000292055 candidate 0 0 0 Last Universal Common Ancestor 4 0 Cellular metabolism,Cellular processes 104 chr11 116717115 116968957 WES breast SIKE1 80143 suppressor of IKBKE 1 1p13.2 7958 26119 611656 "NP_001095866;NP_079349" "NM_001102396;NM_025073" ENSP00000358541 candidate 0 0 0 Eukaryotes 40 0 -1 80 chr1 115316895 115323228 WGS chronic lymphocytic leukemia SIX4 51804 SIX homeobox 4 14q23 6960 10890 606342 NP_059116 NM_017420 ENSP00000216513 candidate 0 0 0 Metazoans 24 8 Cell cycle,Cell motility and interactions,Cellular metabolism,DNA/RNA metabolism and transcription,Development,Regulation of intracellular processes and metabolism,Regulation of transcription -1 chr14 61180128 61190792 WES breast SKP2 6502 S-phase kinase-associated protein 2 (p45) 5p13 3256 10901 601436 "NP_001230049;NP_116026;NP_005974" "NM_001243120;NM_032637;NM_005983" "ENSP00000274255;ENSP00000274254" known 0 0 0 Eukaryotes 117 2 Cell cycle 53 chr5 36152871 36182130 CGC,WES,Amplified glioblastoma SLA 6503 Src-like-adaptor 8q22.3-qter|8q24 3060 10902 601099 "NP_006739;NP_001039021;NP_001039022" "NM_006748;NM_001045556;NM_001045557" ENSP00000337548 candidate 0 0 0 Last Universal Common Ancestor 6 0 -1 95 chr8 134050772 134072525 WGS liver SLC12A9 56996 solute carrier family 12 (potassium/chloride transporters), member 9 7q22 11564 17435 - NP_064631 NM_020246 "ENSP00000443702;ENSP00000413796;ENSP00000275730" candidate 0 0 0 Last Universal Common Ancestor 2 0 -1 97 chr7 100451820 100464224 WGS melanoma SLC15A1 6564 solute carrier family 15 (oligopeptide transporter), member 1 13q33-q34 2768 10920 600544 NP_005064 NM_005073 - candidate 0 0 0 Last Universal Common Ancestor 1 1 Cellular processes 37 chr13 99336981 99378703 WGS acute myeloid leukemia SLC16A4 9122 solute carrier family 16, member 4 (monocarboxylic acid transporter 5) 1p13.3 4855 10925 603878 "NP_001188478;NP_001188477;NP_004687;NP_001188475;NP_001188476" "NM_001201549;NM_001201548;NM_004696;NM_001201546;NM_001201547" "ENSP00000432495;ENSP00000358796;ENSP00000358794" candidate 0 0 0 Eukaryotes 2 2 Cellular processes 7 chr1 110906391 110931945 WES pancreas SLC17A5 26503 solute carrier family 17 (anion/sugar transporter), member 5 6q14-q15 5058 10933 604322 NP_036566 NM_012434 ENSP00000348019 candidate 0 0 0 Last Universal Common Ancestor 2 7 Cellular processes 73 chr6 74304803 74363609 WES melanoma SLC1A6 6511 solute carrier family 1 (high affinity aspartate/glutamate transporter), member 6 19p13.12 9005 10944 600637 NP_005062 NM_005071 ENSP00000221742 candidate 0 0 0 Last Universal Common Ancestor 1 1 Cellular processes,Multicellular activities 15 chr19 15061010 15083722 WES pancreas SLC22A15 55356 solute carrier family 22, member 15 1p13.1 - 20301 608275 NP_060890 NM_018420 ENSP00000358515 candidate 0 0 0 Last Universal Common Ancestor 0 1 Cellular processes -1 chr1 116519249 116609726 WES colorectal SLC24A3 57419 solute carrier family 24 (sodium/potassium/calcium exchanger), member 3 20p13 15352 10977 609839 NP_065740 NM_020689 ENSP00000333519 candidate 0 0 0 Last Universal Common Ancestor 0 0 Cellular processes 52 chr20 19193487 19701781 WGS melanoma SLC24A4 123041 solute carrier family 24 (sodium/potassium/calcium exchanger), member 4 14q32.12 15353 10978 609840 "NP_705933;NP_705932;NP_705934" "NM_153647;NM_153646;NM_153648" - candidate 0 0 0 Last Universal Common Ancestor 14 0 Cellular processes -1 chr14 92790175 92959969 WGS breast SLC25A40 55972 solute carrier family 25, member 40 7q21.12 14372 29680 610821 NP_061331 NM_018843 - candidate 0 0 0 Eukaryotes 0 3 -1 65 chr7 87465567 87488042 WGS chronic lymphocytic leukemia SLC25A48 153328 solute carrier family 25, member 48 5q31.1 14098 30451 - NP_660325 NM_145282 ENSP00000413049 candidate 0 0 0 Eukaryotes 0 0 -1 -1 chr5 135170537 135223770 WES lymphoma SLC29A1 2030 solute carrier family 29 (nucleoside transporters), member 1 6p21.1 3724 11003 602193 "NP_004946;NP_001071645;NP_001071643;NP_001071642;NP_001071644" "NM_004955;NM_001078177;NM_001078175;NM_001078174;NM_001078176" "ENSP00000377427;ENSP00000360805;ENSP00000360820;ENSP00000377424;ENSP00000392668" candidate 0 0 0 Eukaryotes 4 7 DNA/RNA metabolism and transcription 83 chr6 44197125 44201262 WES colorectal SLC29A2 3177 solute carrier family 29 (nucleoside transporters), member 2 11q13 3662 11004 602110 NP_001523 NM_001532 ENSP00000350024 candidate 0 0 0 Eukaryotes 2 0 DNA/RNA metabolism and transcription 22 chr11 66130910 66138798 WES lymphoma SLC29A4 222962 solute carrier family 29 (nucleoside transporters), member 4 7p22.1 15362 23097 609149 "NP_694979;NP_001035751" "NM_153247;NM_001040661" "ENSP00000297195;ENSP00000380081" candidate 0 0 0 Eukaryotes 2 2 -1 -1 chr7 5327448 5342567 WGS liver SLC2A13 114134 solute carrier family 2 (facilitated glucose transporter), member 13 12q12 15363 15956 611036 NP_443117 NM_052885 ENSP00000280871 candidate 0 0 0 Last Universal Common Ancestor 0 1 Cellular processes -1 chr12 40153831 40499610 WES head and neck squamous cell carcinoma SLC2A8 29988 solute carrier family 2 (facilitated glucose transporter), member 8 9q33.3 5580 13812 605245 NP_055395 NM_014580 ENSP00000362469 candidate 0 0 0 Last Universal Common Ancestor 1 0 Cellular processes 10 chr9 130159510 130169525 WGS chronic lymphocytic leukemia SLC34A2 10568 solute carrier family 34 (sodium phosphate), member 2 4p15.2 7251 11020 604217 "NP_001171469;NP_001171470;NP_006415" "NM_001177998;NM_001177999;NM_006424" ENSP00000371483 known 1 0 0 Last Universal Common Ancestor 0 2 Cellular metabolism,Cellular processes 42 chr4 25664123 25678368 CGC lung SLC38A3 10991 solute carrier family 38, member 3 3p21.3 11980 18044 604437 NP_006832 NM_006841 - candidate 0 0 0 - 5 0 Cellular processes 37 chr3 50251633 50257606 HTMS lung SLC38A8 146167 solute carrier family 38, member 8 16q23.3 - 32434 - NP_001073911 NM_001080442 ENSP00000299709 candidate 0 0 0 Last Universal Common Ancestor 0 0 Cellular processes -1 chr16 84043392 84075762 WES lymphoma SLC39A10 57181 solute carrier family 39 (zinc transporter), member 10 2q32.3 10572 20861 608733 "NP_001120729;NP_065075" "NM_001127257;NM_020342" "ENSP00000386766;ENSP00000352655" candidate 0 0 0 Last Universal Common Ancestor 2 7 Cellular processes -1 chr2 196544767 196599762 WGS melanoma SLC44A1 23446 solute carrier family 44, member 1 9q31.2 16197 18798 606105 NP_536856 "NM_080546;NM_022109" - candidate 0 0 0 Eukaryotes 7 9 Cellular processes 18 chr9 108061501 108147783 WGS breast SLC45A2 51151 solute carrier family 45, member 2 5p13.2 5865 16472 606202 "NP_057264;NP_001012527" "NM_016180;NM_001012509" "ENSP00000371534;ENSP00000296589" candidate 0 0 0 Last Universal Common Ancestor 0 0 Cell response to stimuli,Cellular metabolism 43 chr5 33944756 33984688 WGS chronic lymphocytic leukemia SLC45A3 85414 solute carrier family 45, member 3 1q32.1 16312 8642 605097 NP_149093 NM_033102 ENSP00000356113 known 1 0 0 Eukaryotes 2 2 -1 -1 chr1 205628365 205633784 CGC prostate SLC4A10 57282 solute carrier family 4, sodium bicarbonate transporter, member 10 2q23-q24 - 13811 605556 "NP_001171486;NP_001171487;NP_071341" "NM_001178015;NM_001178016;NM_022058" "ENSP00000393066;ENSP00000364664;ENSP00000395797" candidate 0 0 0 Eukaryotes 3 1 Cellular processes 18 chr2 162481029 162833384 WES chronic lymphocytic leukemia SLC6A11 6538 solute carrier family 6 (neurotransmitter transporter, GABA), member 11 3p25.3 6406 11044 607952 NP_055044 NM_014229 - candidate 0 0 0 Last Universal Common Ancestor 0 0 Cellular processes 1 chr3 10857951 10980085 WES melanoma SLC6A15 55117 solute carrier family 6 (neutral amino acid transporter), member 15 12q21.3 12141 13621 607971 "NP_877499;NP_060527;NP_001139807" "NM_182767;NM_018057;NM_001146335" "ENSP00000390706;ENSP00000266682" candidate 0 0 0 Last Universal Common Ancestor 2 0 Cellular processes 9 chr12 85255414 85285899 WES pancreas SLC6A17 388662 solute carrier family 6, member 17 1p13.3 18061 31399 610299 NP_001010898 NM_001010898 ENSP00000405461 candidate 0 0 0 Last Universal Common Ancestor 1 0 Cellular processes -1 chr1 110709552 110741063 WGS prostate SLC6A2 6530 solute carrier family 6 (neurotransmitter transporter, noradrenalin), member 2 16q12.2 1232 11048 163970 "NP_001165975;NP_001165972;NP_001034;NP_001165973" "NM_001172504;NM_001172501;NM_001043;NM_001172502" "ENSP00000369237;ENSP00000394956;ENSP00000457375;ENSP00000219833" candidate 0 0 0 Last Universal Common Ancestor 5 0 Cell response to stimuli,Cellular processes,Multicellular activities 41 chr16 55690607 55739181 HTMS breast,lung,ovarian,pancreas,prostate SLC6A3 6531 solute carrier family 6 (neurotransmitter transporter, dopamine), member 3 5p15.3 543 11049 126455 NP_001035 NM_001044 ENSP00000270349 candidate 0 0 0 Last Universal Common Ancestor 16 0 Cell cycle,Cell response to stimuli,Cellular metabolism,Cellular processes,Development,Immune system response,Multicellular activities,Regulation of intracellular processes and metabolism 32 chr5 1401024 1443312 WES breast SLC7A14 57709 solute carrier family 7 (orphan transporter), member 14 3q26.2 17222 29326 - NP_066000 "NM_020949;NM_175917" - candidate 0 0 0 Last Universal Common Ancestor 1 0 Cellular processes -1 chr3 170184846 170244725 WGS liver SLC8A2 6543 solute carrier family 8 (sodium/calcium exchanger), member 2 19q13.3 15990 11069 601901 NP_055878 NM_015063 ENSP00000236877 candidate 0 0 2 Eukaryotes 5 0 Cellular processes 34 chr19 47933349 47969660 WES melanoma SLC8A3 6547 solute carrier family 8 (sodium/calcium exchanger), member 3 14q24.1 9723 11070 607991 "NP_489479;NP_891981;NP_892114;NP_150287;NP_001123889;NP_891977" "NM_058240;NM_182936;NM_183002;NM_033262;NM_001130417;NM_182933;NM_182932" "ENSP00000216568;ENSP00000350560;ENSP00000349392;ENSP00000377863;ENSP00000370669" candidate 0 0 2 Eukaryotes 4 0 Cellular processes -1 chr14 70512667 70635139 WES breast SLC9A10 285335 solute carrier family 9, member 10 3q13.2 11257 31401 612738 NP_898884 NM_183061 ENSP00000306627 candidate 0 0 0 Eukaryotes 2 0 Cellular processes,Development,Multicellular activities -1 chr3 111870703 112005638 WES breast SLCO1B1 10599 solute carrier organic anion transporter family, member 1B1 12p 9214 10959 604843 NP_006437 NM_006446 ENSP00000256958 candidate 0 0 2 Metazoans 0 2 Cellular processes 2 chr12 21294509 21392120 WES chronic lymphocytic leukemia,melanoma SLCO1B3 28234 solute carrier organic anion transporter family, member 1B3 12p12 12021 10961 605495 NP_062818 NM_019844 ENSP00000370956 candidate 0 0 2 Metazoans 0 0 Cellular processes 2 chr12 20968673 21069178 WGS lymphoma SLIT2 9353 slit homolog 2 (Drosophila) 4p15.2 4776 11086 603746 NP_004778 NM_004787 ENSP00000427548 candidate 0 0 0 Last Universal Common Ancestor 8 0 Cell cycle,Cell motility and interactions,Cell response to stimuli,Development,Immune system response,Multicellular activities,Regulation of intracellular processes and metabolism,Signal transduction 74 chr4 20255439 20620629 WES lung SLITRK3 22865 SLIT and NTRK-like family, member 3 3q26.1 18064 23501 609679 NP_055741 NM_014926 ENSP00000241274 candidate 0 0 0 Eukaryotes 2 0 Cell cycle,Development 35 chr3 164905688 164908618 WES head and neck squamous cell carcinoma SLITRK5 26050 SLIT and NTRK-like family, member 5 13q31.2 18065 20295 609680 NP_056382 NM_015567 ENSP00000366283 candidate 0 0 0 Eukaryotes 0 0 -1 18 chr13 88327644 88330517 WES pancreas SLITRK6 84189 SLIT and NTRK-like family, member 6 13q31.1 15403 23503 609681 NP_115605 NM_032229 ENSP00000383143 candidate 0 0 0 Eukaryotes 3 0 -1 -1 chr13 86368121 86370643 WES lymphoma SLURP1 57152 secreted LY6/PLAUR domain containing 1 8q24.3 5836 18746 606119 NP_065160 NM_020427 ENSP00000246515 candidate 0 0 0 Mammals 0 0 -1 11 chr8 143822564 143823803 WES lung SMAD2 4087 SMAD family member 2 18q21.1 3221 6768 601366 "NP_001129409;NP_005892;NP_001003652" "NM_001135937;NM_005901;NM_001003652" "ENSP00000384449;ENSP00000349282;ENSP00000262160" candidate 0 0 1 Metazoans 418 3 Cellular metabolism,DNA/RNA metabolism and transcription,Development,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction 106 chr18 45368201 45423127 WES colorectal,colorectal (non-hypermutated) SMAD3 4088 SMAD family member 3 15q22.33 8533 6769 603109 "NP_001138576;NP_005893;NP_001138574;NP_001138575" "NM_001145104;NM_005902;NM_001145102;NM_001145103" ENSP00000332973 candidate 0 0 1 Metazoans 417 3 Cell cycle,Cell motility and interactions,Cell response to stimuli,Cellular metabolism,Cellular processes,DNA/RNA metabolism and transcription,Development,Other,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction 100 chr15 67358493 67482871 WES colorectal SMAD4 4089 SMAD family member 4 18q21.1 2995 6770 600993 NP_005350 NM_005359 ENSP00000341551 known 0 1 0 Metazoans 241 19 Cell cycle,Cellular metabolism,Cellular processes,DNA/RNA metabolism and transcription,Development,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction 73 chr18 48573417 48604834 CGC,WES colorectal,pancreas,small intestine ,breast,cholangiocarcinoma,colorectal (non-hypermutated),lung SMARCA1 6594 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1 Xq25 2055 11097 300012 "NP_003060;NP_620604" "NM_003069;NM_139035" "ENSP00000360163;ENSP00000360162" candidate 0 0 1 Last Universal Common Ancestor 19 8 Cell cycle,Cellular metabolism,DNA/RNA metabolism and transcription,Development,Regulation of intracellular processes and metabolism,Regulation of transcription 90 chrX 128582289 128657347 WES lymphoma SMARCA4 6597 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 19p13.2 4459 11100 603254 "NP_001122321;NP_001122316;NP_001122318;NP_001122317;NP_001122319;NP_001122320;NP_003063" "NM_001128849;NM_001128844;NM_001128846;NM_001128845;NM_001128847;NM_001128848;NM_003072" "ENSP00000395654;ENSP00000414727;ENSP00000397783;ENSP00000466963;ENSP00000392837;ENSP00000350720;ENSP00000343896" known 0 1 0 Last Universal Common Ancestor 210 4 Cell cycle,Cellular metabolism,DNA/RNA metabolism and transcription,Development,Regulation of intracellular processes and metabolism,Regulation of transcription 105 chr19 11094828 11170875 CGC,WES,WGS lung,lymphoma,medulloblastoma,pancreas SMARCAD1 56916 SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1 4q22-q23 11586 18398 612761 "NP_001241878;NP_064544;NP_001121902;NP_001121901" "NM_001254949;NR_045644;NM_020159;NM_001128430;NM_001128429" "ENSP00000415576;ENSP00000351947;ENSP00000346217" candidate 0 0 0 Last Universal Common Ancestor 118 3 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription -1 chr4 95129546 95210682 WGS melanoma SMARCB1 6598 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1 22q11.23|22q11 3364 11103 601607 "NP_003064;NP_001007469" "NM_003073;NM_001007468" "ENSP00000383984;ENSP00000263121" known 0 1 0 Eukaryotes 120 4 Cell cycle,Cellular metabolism,DNA/RNA metabolism and transcription,Development,Other,Regulation of intracellular processes and metabolism,Regulation of transcription 104 chr22 24129357 24176364 CGC,WES malignant rhabdoid ,melanoma SMARCD1 6602 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1 12q13-q14 3438 11106 601735 "NP_003067;NP_620710" "NM_003076;NM_139071" "ENSP00000378414;ENSP00000370924" candidate 0 0 0 Last Universal Common Ancestor 37 6 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription 82 chr12 50479153 50492780 WES breast SMC2 10592 structural maintenance of chromosomes 2 9q31.1 9277 14011 605576 "NP_001036015;NP_006435;NP_001036016" "NM_001042550;NM_006444;NM_001042551" "ENSP00000286398;ENSP00000363925" candidate 0 0 0 Last Universal Common Ancestor 44 2 Cell cycle,DNA/RNA metabolism and transcription 47 chr9 106857666 106901593 WGS chronic lymphocytic leukemia SMC3 9126 structural maintenance of chromosomes 3 10q25 5829 2468 606062 NP_005436 NM_005445 ENSP00000354720 candidate 0 0 0 Last Universal Common Ancestor 24 3 Cell cycle,Cellular processes,DNA/RNA metabolism and transcription,Signal transduction 81 chr10 112328696 112364057 WGS glioblastoma SMG5 23381 smg-5 homolog, nonsense mediated mRNA decay factor (C. elegans) 1q21.2 16869 24644 610962 NP_056142 NM_015327 ENSP00000355261 candidate 0 0 0 Eukaryotes 6 0 Cellular metabolism,Cellular processes,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription 44 chr1 156220381 156252471 WGS melanoma SMO 6608 smoothened, frizzled family receptor 7q32.3 3294 11119 601500 NP_005622 NM_005631 ENSP00000249373 known 1 0 0 Metazoans 1 5 Cell cycle,Cell motility and interactions,DNA/RNA metabolism and transcription,Development,Regulation of intracellular processes and metabolism,Signal transduction 48 chr7 128828993 128852289 CGC skin SMTN 6525 smoothelin 22q12.2 3675 11126 602127 "NP_599032;NP_001193947;NP_008863;NP_599031;NP_001193946" "NM_134270;NM_001207018;NM_006932;NM_134269;NM_001207017" "ENSP00000328635;ENSP00000329532;ENSP00000351593" candidate 0 0 0 Metazoans 9 0 Development,Multicellular activities 65 chr22 31479164 31500449 WES colorectal SMURF1 57154 SMAD specific E3 ubiquitin protein ligase 1 7q22.1 6902 16807 605568 "NP_065162;NP_001186776;NP_851994" "NM_020429;NM_001199847;NM_181349" "ENSP00000354621;ENSP00000355326" known 0 0 1 Eukaryotes 126 0 Cellular metabolism,Cellular processes,Development,Regulation of intracellular processes and metabolism,Signal transduction 89 chr7 98628210 98741403 CGC,Amplified SMURF2 64750 SMAD specific E3 ubiquitin protein ligase 2 17q22-q23 6901 16809 605532 NP_073576 NM_022739 - candidate 0 0 1 Eukaryotes 140 3 Cellular metabolism,Cellular processes,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction 77 chr17 62541969 62657998 WES melanoma SNED1 25992 sushi, nidogen and EGF-like domains 1 2q37.3 - 24696 - NP_001073906 NM_001080437 ENSP00000308893 candidate 0 0 0 Last Universal Common Ancestor 2 1 Cell motility and interactions 65 chr2 241938255 242026891 WGS breast SNRPA 6626 small nuclear ribonucleoprotein polypeptide A 19q13.1 1658 11151 182285 NP_004587 NM_004596 ENSP00000243563 candidate 0 0 0 Eukaryotes 66 0 DNA/RNA metabolism and transcription,Regulation of transcription 90 chr19 41257314 41271069 WES melanoma SNX29 92017 sorting nexin 29 16p13.13-p13.12 17437 30542 - "NP_115543;NP_001073999" "NM_032167;NM_001009607;NM_001080530" ENSP00000456480 known 1 0 0 Eukaryotes 1 1 -1 4 chr16 12093153 12662483 CGC lymphoma SNX4 8723 sorting nexin 4 3q21.2 9334 11175 605931 NP_003785 NM_003794 ENSP00000251775 candidate 0 0 0 Eukaryotes 20 2 Cellular processes 96 chr3 125166626 125239016 WGS breast SNX7 51375 sorting nexin 7 1p21.3 15416 14971 - "NP_689424;NP_057060" "NM_152238;NR_033716;NM_015976" "ENSP00000304429;ENSP00000434731" candidate 0 0 1 Eukaryotes 13 7 Cellular processes 70 chr1 99127288 99225684 WES,WGS chronic lymphocytic leukemia SOCS1 8651 suppressor of cytokine signaling 1 16p13.13 4669 19383 603597 NP_003736 NM_003745 ENSP00000329418 known 0 1 0 Vertebrates 7 7 Cell cycle,Cellular metabolism,Cellular processes,Development,Regulation of intracellular processes and metabolism,Signal transduction 43 chr16 11348703 11349335 CGC,WES lymphoma SON 6651 SON DNA binding protein 21q22.1-q22.2|21q22.11 1678 11183 182465 "NP_620305;NP_115571" "NM_003103;NM_138925;NM_138926;NM_138927;NM_032195;NM_058183" "ENSP00000300278;ENSP00000348984" candidate 0 0 0 Last Universal Common Ancestor 55 10 Cell cycle,Development,Regulation of intracellular processes and metabolism 109 chr21 34915399 34948727 WES pancreas SORCS1 114815 sortilin-related VPS10 domain containing receptor 1 10q23-q25 12098 16697 606283 "NP_001193499;NP_443150;NP_001013049;NP_001193500;NP_001193498;NP_001193501" "NM_001206570;NM_052918;NM_001013031;NM_001206571;NM_001206569;NM_001206572" ENSP00000345964 candidate 0 0 0 Eukaryotes 2 0 Signal transduction -1 chr10 108336982 108924284 WES pancreas SORL1 6653 sortilin-related receptor, L(DLR class) A repeats containing 11q23.2-q24.2 3595 11185 602005 NP_003096 NM_003105 ENSP00000260197 candidate 0 0 0 Eukaryotes 14 0 Cellular metabolism,Cellular processes 106 chr11 121323041 121500269 WES breast,colorectal SOS1 6654 son of sevenless homolog 1 (Drosophila) 2p21 1681 11187 182530 NP_005624 NM_005633 ENSP00000384675 candidate 0 0 0 Eukaryotes 86 0 Signal transduction 85 chr2 39212968 39347563 HTMS breast,lung,ovarian,pancreas,prostate SOX15 6665 SRY (sex determining region Y)-box 15 17p12.3 3191 11196 601297 NP_008873 NM_006942 ENSP00000355354 candidate 0 0 0 Eukaryotes 1 0 Cell cycle,Cellular metabolism,DNA/RNA metabolism and transcription,Development,Multicellular activities,Regulation of intracellular processes and metabolism,Regulation of transcription 65 chr17 7491699 7492994 WGS lymphoma SOX2 6657 SRY (sex determining region Y)-box 2 3q26.3-q27 8921 11195 184429 NP_003097 NM_003106 ENSP00000323588 known 1 0 0 Eukaryotes 0 6 Cell response to stimuli,Cellular metabolism,DNA/RNA metabolism and transcription,Development,Multicellular activities,Regulation of intracellular processes and metabolism,Regulation of transcription 61 chr3 181430149 181431099 CGC lung,oesophageal SOX5 6660 SRY (sex determining region Y)-box 5 12p12.1 18086 11201 604975 "NP_821078;NP_694534;NP_008871" "NM_178010;NM_152989;NM_006940" "ENSP00000370788;ENSP00000398273;ENSP00000308927" candidate 0 0 0 Eukaryotes 11 5 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription 31 chr12 23687156 24102535 WES pancreas SOX8 30812 SRY (sex determining region Y)-box 8 16p13.3 16175 11203 605923 NP_055402 NM_014587 ENSP00000293894 candidate 0 0 0 Eukaryotes 4 0 Cell cycle,Cellular metabolism,DNA/RNA metabolism and transcription,Development,Regulation of intracellular processes and metabolism,Regulation of transcription -1 chr16 1031923 1035383 WGS lymphoma SOX9 6662 SRY (sex determining region Y)-box 9 17q23 6427 11204 608160 NP_000337 NM_000346 ENSP00000245479 candidate 0 0 0 Eukaryotes 1 6 Cell cycle,Cell motility and interactions,Cellular metabolism,DNA/RNA metabolism and transcription,Development,Multicellular activities,Regulation of intracellular processes and metabolism,Regulation of transcription 79 chr17 70117533 70120525 WES colorectal (non-hypermutated) SP1 6667 Sp1 transcription factor 12q13.1 1796 11205 189906 "NP_612482;NP_003100;NP_001238754" "NM_138473;NM_003109;NM_001251825" ENSP00000404263 candidate 0 0 0 Last Universal Common Ancestor 282 17 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription 10 chr12 53775442 53805021 WGS breast SP110 3431 SP110 nuclear body protein 2q37.1 6832 5401 604457 "NP_001171944;NP_004500;NP_536349;NP_004501" "NM_001185015;NM_004509;NM_080424;NM_004510" "ENSP00000439558;ENSP00000351488;ENSP00000258382;ENSP00000258381" candidate 0 0 0 Eukaryotes 18 1 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription 106 chr2 231033843 231081642 WES breast SPAG1 6674 sperm associated antigen 1 8q22.2 4548 11212 603395 "NP_757367;NP_003105" "NM_172218;NM_003114" "ENSP00000373450;ENSP00000251809" candidate 0 0 0 Last Universal Common Ancestor 5 4 Development 38 chr8 101174509 101253247 WGS melanoma SPAG17 200162 sperm associated antigen 17 1p12 10146 26620 - NP_996879 NM_206996 ENSP00000337804 candidate 0 0 0 Eukaryotes 56 0 -1 -1 chr1 118506425 118727780 WES,WGS liver,prostate SPANXN2 494119 SPANX family, member N2 Xq27.3 18091 33175 300665 NP_001009615 NM_001009615 ENSP00000359529 candidate 0 0 3 Opisthokonts 0 0 -1 -1 chrX 142795138 142803762 WES gastric SPATA13 221178 spermatogenesis associated 13 13q12.12 15427 23222 613324 "NP_694568;NP_001159743" "NM_153023;NM_001166271" "ENSP00000371542;ENSP00000371527" candidate 0 0 0 Eukaryotes 1 2 Signal transduction -1 chr13 24797068 24876908 WGS melanoma SPATA18 132671 spermatogenesis associated 18 4q12 14050 29579 612814 NP_660306 NM_145263 ENSP00000295213 candidate 0 0 0 Metazoans 0 1 Development,Multicellular activities -1 chr4 52917871 52960737 WGS chronic lymphocytic leukemia SPATA7 55812 spermatogenesis associated 7 14q31.3 15431 20423 609868 "NP_001035518;NP_060888" "NM_001040428;NM_018418" "ENSP00000348991;ENSP00000377176" candidate 0 0 0 Metazoans 1 0 -1 22 chr14 88857724 88904763 WGS glioblastoma SPDEF 25803 SAM pointed domain containing ets transcription factor 6p21.3 12176 17257 608144 "NP_036523;NP_001239223" "NM_012391;NM_001252294" "ENSP00000442715;ENSP00000363149" candidate 0 0 0 Metazoans 4 3 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription 64 chr6 34506054 34512232 WGS melanoma SPECC1 92521 sperm antigen with calponin homology and coiled-coil domains 1 17p11.2 12301 30615 608793 "NP_001230368;NP_001028725;NP_001028727;NP_690868;NP_001230367;NP_001028726" "NM_001243439;NM_001033553;NM_001033555;NM_152904;NM_001243438;NM_001033554" "ENSP00000261503;ENSP00000378898;ENSP00000378900" known 1 0 0 Metazoans 5 1 -1 -1 chr17 19999965 20217375 CGC,WES leukemia,lymphoma SPHKAP 80309 SPHK1 interactor, AKAP domain containing 2q36 18052 30619 611646 "NP_001136116;NP_085126" "NM_001142644;NM_030623" "ENSP00000375909;ENSP00000339886" candidate 0 0 0 Vertebrates 1 0 -1 -1 chr2 228846436 228996803 WES lung SPINT4 391253 serine peptidase inhibitor, Kunitz type 4 20q13.12 - 16130 - NP_848550 NM_178455 - candidate 0 0 0 Eukaryotes 0 1 -1 -1 chr20 44351007 44352697 WGS lung SPO11 23626 SPO11 meiotic protein covalently bound to DSB homolog (S. cerevisiae) 20q13.31 9236 11250 605114 "NP_937998;NP_036576" "NM_198265;NM_012444" "ENSP00000360310;ENSP00000316034" candidate 0 0 0 Last Universal Common Ancestor 0 1 Cell cycle,DNA/RNA metabolism and transcription,Development,Multicellular activities 16 chr20 55904924 55918513 WGS melanoma SPOP 8405 speckle-type POZ protein 17q21.33 16004 11254 602650 "NP_001007227;NP_001007228;NP_003554;NP_001007229;NP_001007230;NP_001007231" "NM_001007226;NM_001007227;NM_003563;NM_001007228;NM_001007229;NM_001007230" "ENSP00000377004;ENSP00000240327;ENSP00000377001" candidate 0 0 1 Eukaryotes 38 0 DNA/RNA metabolism and transcription,Regulation of transcription 106 chr17 47677743 47700172 HTMS,WES,WGS breast,lung,ovarian,pancreas,prostate,endometrium SPRR2B 6701 small proline-rich protein 2B 1q21-q22 - 11262 182268 NP_001017418 NM_001017418 ENSP00000340703 candidate 0 0 6 Primates 0 0 Development 19 chr1 153043100 153043315 WES gastric SPRY3 10251 sprouty homolog 3 (Drosophila) Xq28 and Yq12 3917 11271 300531 NP_005831 NM_005840 ENSP00000302978 candidate 0 0 1 Eukaryotes 1 0 Signal transduction -1 chrX 155003534 155004397 WES chronic lymphocytic leukemia SPTA1 6708 spectrin, alpha, erythrocytic 1 (elliptocytosis 2) 1q21 1685 11272 182860 NP_003117 NM_003126 ENSP00000357130 candidate 0 0 0 Eukaryotes 30 3 Cellular metabolism,Cellular processes,Development,Regulation of intracellular processes and metabolism 54 chr1 158581057 158655137 WES,WGS gastric,melanoma,prostate SPTAN1 6709 spectrin, alpha, non-erythrocytic 1 (alpha-fodrin) 9q34.11 1684 11273 182810 "NP_003118;NP_001182461;NP_001123910" "NM_003127;NM_001195532;NM_001130438" "ENSP00000361824;ENSP00000361816" candidate 0 0 0 Last Universal Common Ancestor 131 1 Cellular metabolism,Cellular processes,Regulation of intracellular processes and metabolism 99 chr9 131329020 131395610 WES breast SPTB 6710 spectrin, beta, erythrocytic 14q23-q24.2 1686 11274 182870 "NP_001020029;NP_000338" "NM_001024858;NM_000347" "ENSP00000374371;ENSP00000374372" candidate 0 0 0 Eukaryotes 20 1 Cellular metabolism,Cellular processes,Regulation of intracellular processes and metabolism 45 chr14 65216027 65289812 WGS lung SPTBN4 57731 spectrin, beta, non-erythrocytic 4 19q13.13 9372 14896 606214 "NP_079489;NP_066022" "NM_025213;NM_020971" "ENSP00000469242;ENSP00000375877" candidate 0 0 0 Eukaryotes 20 0 Cellular metabolism,Cellular processes,Regulation of intracellular processes and metabolism 31 chr19 40978529 41081472 WES kidney SRGAP3 9901 SLIT-ROBO Rho GTPase activating protein 3 3p25.3 12108 19744 606525 "NP_055665;NP_001028289" "NM_014850;NM_001033117;NM_001033116" "ENSP00000353587;ENSP00000373347" known 1 0 0 Eukaryotes 9 0 Signal transduction 54 chr3 9027206 9290635 CGC,WGS pilocytic astrocytoma,prostate SRPX 8406 sushi-repeat containing protein, X-linked Xp21.1 2175 11309 300187 "NP_001164221;NP_001164222;NP_006298;NP_001164223" "NM_001170750;NM_001170751;NM_006307;NM_001170752" "ENSP00000440758;ENSP00000411165;ENSP00000445034;ENSP00000367794" candidate 0 0 0 Eukaryotes 4 1 -1 94 chrX 38008967 38037598 WES lymphoma SRRM1 10250 serine/arginine repetitive matrix 1 1p36.11 10441 16638 605975 NP_005830 NM_005839 ENSP00000326261 candidate 0 0 1 Eukaryotes 123 2 DNA/RNA metabolism and transcription,Regulation of transcription 109 chr1 24972475 24998774 WGS acute myeloid leukemia SRSF1 6426 serine/arginine-rich splicing factor 1 17q22 2887 10780 600812 "NP_001071634;NP_008855" "NR_034041;NM_001078166;NM_006924" - candidate 0 0 0 Last Universal Common Ancestor 145 10 DNA/RNA metabolism and transcription,Regulation of transcription 109 chr17 56082770 56084498 WES chronic lymphocytic leukemia SRSF11 9295 serine/arginine-rich splicing factor 11 1p31 3599 10782 602010 "NP_001177916;NP_004759" "NM_001190987;NM_004768" ENSP00000359989 candidate 0 0 0 Eukaryotes 60 3 DNA/RNA metabolism and transcription,Regulation of transcription 106 chr1 70687320 70716485 WGS prostate SRSF2 6427 serine/arginine-rich splicing factor 2 17q25.1 2888 10783 600813 "NP_001182356;NP_003007" "NM_001195427;NR_036608;NM_003016" "ENSP00000353089;ENSP00000376276" known 1 0 1 Eukaryotes 92 6 DNA/RNA metabolism and transcription,Regulation of transcription 109 chr17 74732246 74733242 CGC,WES leukemia,myelodysplasia SRSF3 6428 serine/arginine-rich splicing factor 3 6p21 4530 10785 603364 NP_003008 "NM_003017;NR_036610" - known 1 0 4 Eukaryotes 113 2 DNA/RNA metabolism and transcription,Regulation of transcription 109 chr11 18686597 18687095 CGC lymphoma SRSF6 6431 serine/arginine-rich splicing factor 6 20q12-q13.1 9054 10788 601944 NP_006266 "NM_006275;NR_034009" ENSP00000244020 candidate 0 0 1 Last Universal Common Ancestor 35 4 DNA/RNA metabolism and transcription,Regulation of transcription 108 chr20 42086674 42089700 WES colorectal SS18 6760 synovial sarcoma translocation, chromosome 18 18q11.2 2559 11340 600192 "NP_005628;NP_001007560" "NM_005637;NM_001007559" ENSP00000414516 known 1 0 0 Eukaryotes 21 3 -1 78 chr18 23612363 23670533 CGC sarcoma SS18L1 26039 synovial sarcoma translocation gene on chromosome 18-like 1 20q13.3 9398 15592 606472 NP_945173 "NM_015558;NM_198935" ENSP00000333012 known 1 0 0 Eukaryotes 28 0 -1 65 chr20 60718877 60749700 CGC,WGS sarcoma,lymphoma SSB 6741 Sjogren syndrome antigen B (autoantigen La) 2q31.1 168 11316 109090 NP_003133 NM_003142 ENSP00000260956 candidate 0 0 4 Eukaryotes 26 0 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of transcription 86 chr2 170657471 170668263 WES melanoma SSH3 54961 slingshot homolog 3 (Drosophila) 11q13.2 9488 30581 606780 NP_060327 "NM_018276;NM_017857" ENSP00000312081 candidate 0 0 0 Last Universal Common Ancestor 5 1 Cellular metabolism,Cellular processes 80 chr11 67071097 67079355 WGS melanoma SSX1 6756 synovial sarcoma, X breakpoint 1 Xp11.23 2428 11335 312820 NP_005626 NM_005635 ENSP00000366118 known 1 0 2 Eukaryotes 2 3 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription 34 chrX 48116677 48125819 CGC sarcoma SSX2 6757 synovial sarcoma, X breakpoint 2 Xp11.22 2180 11336 300192 "NP_003138;NP_783629" "NM_003147;NM_175698" "ENSP00000338796;ENSP00000338561" known 1 0 2 Eukaryotes 4 0 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription 6 chrX 52727082 52734799 CGC sarcoma SSX4 6759 synovial sarcoma, X breakpoint 4 Xp11.23 2266 11338 300326 "NP_005627;NP_783856" "NM_005636;NM_175729" ENSP00000366083 known 1 0 3 Eukaryotes 4 0 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription 1 chrX 48262901 48270814 CGC sarcoma ST6GAL2 84620 ST6 beta-galactosamide alpha-2,6-sialyltranferase 2 2q11.2-q12.1 12237 10861 608472 "NP_001135823;NP_115917;NP_001135824" "NM_001142351;NM_032528;NM_001142352" "ENSP00000386942;ENSP00000387332;ENSP00000355273" candidate 0 0 0 Eukaryotes 1 0 Cellular metabolism,Cellular processes -1 chr2 107423137 107460433 WES pancreas ST6GALNAC3 256435 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3 1p31.1 15341 19343 610133 "NP_001153483;NP_694541" "NM_001160011;NM_152996" - candidate 0 0 0 Eukaryotes 0 0 Cellular metabolism,Cellular processes -1 chr1 76779484 77094488 WES melanoma STAB1 23166 stabilin 1 3p21.1 9778 18628 608560 NP_055951 NM_015136 ENSP00000312946 candidate 0 0 0 Last Universal Common Ancestor 2 0 Cell response to stimuli,Cellular processes,Development,Immune system response 90 chr3 52529430 52558369 WES colorectal STARD3 10948 StAR-related lipid transfer (START) domain containing 3 17q11-q12 6132 17579 607048 "NP_001159410;NP_001159409;NP_006795" "NM_001165938;NM_001165937;NM_006804" - known 0 0 0 Eukaryotes 0 0 Cellular metabolism,Cellular processes 48 chr17 37809785 37819158 CGC,Amplified STARD8 9754 StAR-related lipid transfer (START) domain containing 8 Xq13.1 6730 19161 300689 "NP_055540;NP_001135975;NP_001135976" "NM_014725;NM_001142503;NM_001142504" "ENSP00000363727;ENSP00000363725;ENSP00000252336" candidate 0 0 0 Eukaryotes 0 0 Signal transduction 60 chrX 67867725 67944261 WES breast STAT3 6774 signal transducer and activator of transcription 3 (acute-phase response factor) 17q21.31 26 11364 102582 "NP_644805;NP_003141;NP_998827" "NM_139276;NM_003150;NM_213662" ENSP00000264657 candidate 0 0 0 Eukaryotes 206 7 Cellular metabolism,DNA/RNA metabolism and transcription,Development,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction 108 chr17 40467766 40500534 WES lymphoma STAT4 6775 signal transducer and activator of transcription 4 2q32.2-q32.3 2779 11365 600558 "NP_001230764;NP_003142" "NM_001243835;NM_003151" "ENSP00000351255;ENSP00000376134" candidate 0 0 0 Eukaryotes 2 0 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction 69 chr2 191895683 192012929 WES melanoma STAT6 6778 signal transducer and activator of transcription 6, interleukin-4 induced 12q13 3302 11368 601512 "NP_001171552;NP_001171550;NP_003144;NP_001171551;NP_001171549" "NM_001178081;NM_001178079;NM_003153;NM_001178080;NR_033659;NM_001178078" ENSP00000300134 candidate 0 0 0 Eukaryotes 59 2 Cell cycle,Cell response to stimuli,Cellular metabolism,DNA/RNA metabolism and transcription,Development,Immune system response,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction 102 chr12 57490358 57502061 WES lymphoma STC1 6781 stanniocalcin 1 8p21-p11.2 3115 11373 601185 NP_003146 NM_003155 ENSP00000290271 candidate 0 0 0 Metazoans 0 0 Cell response to stimuli,Regulation of intracellular processes and metabolism,Signal transduction 66 chr8 23702286 23712036 WES melanoma STIL 6491 SCL/TAL1 interrupting locus 1q32|1p32 1627 10879 181590 "NP_003026;NP_001041631" "NM_003035;NM_001048166" "ENSP00000360944;ENSP00000337367" known 1 0 0 Eukaryotes 1 3 -1 44 chr1 47716811 47775991 CGC leukemia STIP1 10963 stress-induced-phosphoprotein 1 11q13 5454 11387 605063 NP_006810 NM_006819 ENSP00000305958 candidate 0 0 1 Last Universal Common Ancestor 21 2 -1 58 chr11 63960547 63971595 WGS liver STK11 6794 serine/threonine kinase 11 19p13.3 3740 11389 602216 NP_000446 NM_000455 ENSP00000324856 known 0 1 0 Last Universal Common Ancestor 59 2 Cell cycle,Cellular metabolism,Cellular processes 73 chr19 1206913 1226643 CGC,HTMS,WES lung,pancreas,breast,ovarian,prostate STK19 8859 serine/threonine kinase 19 6p21.3 7281 11398 604977 "NP_115830;NP_004188" "NM_032454;NR_026717;NM_004197" "ENSP00000364480;ENSP00000364482" candidate 0 0 0 Eukaryotes 13 0 Cellular metabolism,Cellular processes 107 chr6 31939774 31981561 WGS melanoma STL 7955 six-twelve leukemia 6q22.33 - - 602532 - NR_026876 - known 1 0 -1 - 0 0 -1 -1 - 0 0 CGC leukemia STRA6 64220 stimulated by retinoic acid gene 6 homolog (mouse) 15q24.1 18122 30650 610745 "NP_071764;NP_001136091;NP_001185969;NP_001136089;NP_001185970;NP_001136092;NP_001185971;NP_001136090" "NM_022369;NM_001142619;NM_001199040;NM_001142617;NM_001199041;NM_001142620;NM_001199042;NM_001142618" "ENSP00000326085;ENSP00000413012;ENSP00000407176;ENSP00000440238;ENSP00000458827;ENSP00000456609;ENSP00000378537" candidate 0 0 0 Eukaryotes 0 0 -1 61 chr15 74472424 74494860 WGS melanoma STYK1 55359 serine/threonine/tyrosine kinase 1 12p13.2 15447 18889 611433 NP_060893 NM_018423 ENSP00000075503 candidate 0 0 0 Last Universal Common Ancestor 2 0 Cellular metabolism,Cellular processes 63 chr12 10772746 10787217 WES head and neck squamous cell carcinoma SUFU 51684 suppressor of fused homolog (Drosophila) 10q24.32 6124 16466 607035 "NP_057253;NP_001171604" "NM_016169;NM_001178133" "ENSP00000358915;ENSP00000358918" known 0 1 0 Last Universal Common Ancestor 38 1 Cell cycle,Cellular metabolism,DNA/RNA metabolism and transcription,Development,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction -1 chr10 104263910 104389909 CGC medulloblastoma SULF2 55959 sulfatase 2 20q12-q13.2 18130 20392 610013 "NP_061325;NP_940998;NP_001155313" "NM_018837;NM_198596;NM_001161841" "ENSP00000418290;ENSP00000418442" candidate 0 0 0 Last Universal Common Ancestor 1 1 Cellular metabolism -1 chr20 46288142 46386107 WES breast SUSD2 56241 sushi domain containing 2 22q11-q12 18132 30667 - NP_062547 NM_019601 ENSP00000351075 candidate 0 0 0 Eukaryotes 3 0 -1 -1 chr22 24577488 24584296 WGS lymphoma SUSD3 203328 sushi domain containing 3 9q22.31 15453 28391 - NP_659443 NM_145006 ENSP00000364621 candidate 0 0 0 Vertebrates 1 1 -1 -1 chr9 95821025 95847026 WGS lung SUZ12 23512 suppressor of zeste 12 homolog (Drosophila) 17q11.2 6949 17101 606245 NP_056170 NM_015355 ENSP00000316578 known 1 0 0 Eukaryotes 13 7 Cell cycle,Cellular metabolism,Cellular processes,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription 100 chr17 30264266 30326019 CGC endometrium SYK 6850 spleen tyrosine kinase 9q22 2514 11491 600085 "NP_001128524;NP_001167639;NP_001167638;NP_003168" "NM_001135052;NM_001174168;NM_001174167;NM_003177" "ENSP00000364904;ENSP00000364898;ENSP00000364899;ENSP00000364907" known 1 0 0 Last Universal Common Ancestor 135 0 Cell cycle,Cell motility and interactions,Cell response to stimuli,Cellular metabolism,Cellular processes,Development,Immune system response,Regulation of intracellular processes and metabolism,Signal transduction 16 chr9 93606181 93657879 CGC,HTMS,WES lymphoma,myelodysplasia,sarcoma SYN2 6854 synapsin II 3p25 2857 11495 600755 "NP_598328;NP_003169" "NM_133625;NM_003178" - candidate 0 0 0 Eukaryotes 1 0 Cellular processes,Multicellular activities,Signal transduction 83 chr3 12046026 12232122 WES lymphoma SYNE1 23345 spectrin repeat containing, nuclear envelope 1 6q25 9762 17089 608441 "NP_892006;NP_149062" "NM_133650;NM_182961;NM_015293;NM_001134379;NM_001099267;NM_033071" "ENSP00000396024;ENSP00000356224" candidate 0 0 0 Eukaryotes 26 11 Cellular processes,Development 47 chr6 152477044 152949466 WES,WGS head and neck squamous cell carcinoma,chronic lymphocytic leukemia SYNE2 23224 spectrin repeat containing, nuclear envelope 2 14q23.2 9763 17084 608442 "NP_878914;NP_878918;NP_055995;NP_878917" "NM_182910;NM_182914;NM_182912;NM_015180;NM_182913" "ENSP00000341781;ENSP00000396794;ENSP00000391937;ENSP00000350719" candidate 0 0 0 Eukaryotes 7 11 -1 89 chr14 64375867 64692241 WES,WGS kidney,glioblastoma SYNGR1 9145 synaptogyrin 1 22q13.1 6800 11498 603925 "NP_663791;NP_663783;NP_004702" "NM_145738;NM_145731;NM_004711" "ENSP00000332287;ENSP00000318845;ENSP00000370946" candidate 0 0 0 Eukaryotes 2 2 -1 77 chr22 39746016 39777916 WGS glioblastoma SYNJ1 8867 synaptojanin 1 21q22.2 9182 11503 604297 "NP_001153774;NP_982271;NP_003886;NP_001153778" "NM_001160302;NM_203446;NM_003895;NM_001160306" "ENSP00000349903;ENSP00000371931;ENSP00000371939" candidate 0 0 0 Eukaryotes 35 5 Cellular metabolism,Cellular processes 70 chr21 34003308 34100351 WGS lymphoma SYNPO2 171024 synaptopodin 2 4q26 15456 17732 - "NP_597734;NP_001122406;NP_001122405" "NM_133477;NM_001128934;NM_001128933" ENSP00000306015 candidate 0 0 0 Eukaryotes 8 1 -1 -1 chr4 119810192 119979086 WGS chronic lymphocytic leukemia SYT14L 401135 synaptotagmin XIV-like 4q13.2 18501 33429 610892 - "NR_027094;NM_001014372" - candidate 0 0 -1 Eukaryotes 0 0 -1 -1 - 0 0 WES colorectal SYT4 6860 synaptotagmin IV 18q12.3 2519 11512 600103 NP_065834 NM_020783 ENSP00000255224 candidate 0 0 0 Eukaryotes 10 2 Cellular processes,Multicellular activities,Signal transduction -1 chr18 40850309 40854360 WES,WGS melanoma,chronic lymphocytic leukemia SZT2 23334 seizure threshold 2 homolog (mouse) 1p34.2 11085 29040 - NP_056099 "NM_001012960;NM_182518;NM_015284;NM_001012961" ENSP00000457168 candidate 0 0 0 - 2 0 -1 88 chr1 43868848 43916148 WES,WGS breast TAAR9 134860 trace amine associated receptor 9 (gene/pseudogene) 6q23.2 16308 20977 608282 NP_778227 NM_175057 ENSP00000424607 candidate 0 0 2 - 0 0 Signal transduction -1 chr6 132859429 132860472 WGS glioblastoma TACC2 10579 transforming, acidic coiled-coil containing protein 2 10q26 5600 11523 605302 "NP_996744;NP_996742;NP_996743;NP_008928" "NM_206862;NM_206860;NM_206861;NM_006997" "ENSP00000260733;ENSP00000353763;ENSP00000425062;ENSP00000358001" candidate 0 0 0 Last Universal Common Ancestor 14 1 -1 78 chr10 123809950 124013568 WES breast TADA2A 6871 transcriptional adaptor 2A 17q12-q21 3784 11531 602276 "NP_001479;NP_597683;NP_001159577" "NM_001488;NM_133439;NM_001166105" "ENSP00000225396;ENSP00000406699" candidate 0 0 0 Eukaryotes 117 0 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription 35 chr17 35783611 35837084 WGS breast TAF1 6872 TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa Xq13.1 2436 11535 313650 "NP_620278;NP_004597" "NM_138923;NM_004606" "ENSP00000406549;ENSP00000362895" candidate 0 0 1 Eukaryotes 80 5 Cell cycle,Cellular metabolism,Cellular processes,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription 61 chrX 70586165 70683893 WES breast TAF15 8148 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa 17q11.1-q11.2 9031 11547 601574 "NP_003478;NP_631961" "NM_003487;NM_139215" "ENSP00000309558;ENSP00000466950" known 1 0 0 Eukaryotes 53 7 -1 83 chr17 34144719 34172043 CGC leukemia,sarcoma TAF2 6873 TAF2 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 150kDa 8q24.12 7060 11536 604912 NP_003175 NM_003184 ENSP00000367406 candidate 0 0 0 Last Universal Common Ancestor 23 2 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription 69 chr8 120744167 120844804 WES colorectal TAF4B 6875 TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa 18q11.2 - 11538 601689 "NP_005631;XP_003403744" "NM_005640;XM_003403696" ENSP00000269142 candidate 0 0 0 Last Universal Common Ancestor 3 2 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription 54 chr18 23806898 23969973 WGS lung TAL1 6886 T-cell acute lymphocytic leukemia 1 1p32 1753 11556 187040 NP_003180 NM_003189 ENSP00000294339 known 1 0 0 Metazoans 70 0 Cellular metabolism,DNA/RNA metabolism and transcription,Development,Multicellular activities,Regulation of intracellular processes and metabolism,Regulation of transcription 83 chr1 47685395 47691560 CGC leukemia TAL2 6887 T-cell acute lymphocytic leukemia 2 9q32 1735 11557 186855 NP_005412 NM_005421 ENSP00000334547 known 1 0 0 Vertebrates 0 0 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription -1 chr9 108424778 108425101 CGC leukemia TAS2R60 338398 taste receptor, type 2, member 60 7q35 18159 20639 613968 NP_803186 NM_177437 ENSP00000327724 candidate 0 0 0 Mammals 0 0 Cell response to stimuli,Signal transduction -1 chr7 143140546 143141499 WES melanoma TBC1D23 55773 TBC1 domain family, member 23 3q12.2 7727 25622 - "NP_001186127;NP_060779" "NM_001199198;NM_018309" "ENSP00000377700;ENSP00000340693" candidate 0 0 0 Eukaryotes 4 0 Regulation of intracellular processes and metabolism,Signal transduction -1 chr3 99979863 100042509 WGS liver TBC1D30 23329 TBC1 domain family, member 30 12q14.3 - 29164 - NP_056094 NM_015279 ENSP00000440640 candidate 0 0 0 Eukaryotes 0 1 Regulation of intracellular processes and metabolism,Signal transduction 32 chr12 65218660 65269565 WGS melanoma TBL1XR1 79718 transducin (beta)-like 1 X-linked receptor 1 3q26.32 15476 29529 608628 NP_078941 NM_024665 - candidate 0 0 2 Last Universal Common Ancestor 32 3 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription 69 chr3 176744158 176782765 WES breast,lymphoma TBX18 9096 T-box 18 6q14-q15 - 11595 604613 NP_001073977 NM_001080508 ENSP00000358677 candidate 0 0 0 Metazoans 0 0 Cell cycle,Cellular metabolism,DNA/RNA metabolism and transcription,Development,Other,Regulation of intracellular processes and metabolism,Regulation of transcription -1 chr6 85446406 85473899 WES,WGS pancreas,lung TBX22 50945 T-box 22 Xq21.1 2253 11600 300307 "NP_001103349;NP_058650;NP_001103348" "NM_001109879;NM_016954;NM_001109878" "ENSP00000362393;ENSP00000396394;ENSP00000362390" candidate 0 0 0 Metazoans 2 4 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription -1 chrX 79277769 79286607 HTMS,WES breast,lung,ovarian,pancreas,prostate,colorectal TBX3 6926 T-box 3 12q24.1 3373 11602 601621 "NP_005987;NP_057653" "NM_005996;NM_016569" "ENSP00000257567;ENSP00000257566" candidate 0 0 0 Eukaryotes 7 3 Cell cycle,Cellular metabolism,Cellular processes,DNA/RNA metabolism and transcription,Development,Multicellular activities,Other,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction 23 chr12 115109649 115121005 WES breast TCEA1 6917 transcription elongation factor A (SII), 1 8q11.2 3252 11612 601425 "NP_006747;NP_958845" "NM_006756;NM_201437" "ENSP00000428426;ENSP00000395483" known 1 0 2 Last Universal Common Ancestor 9 1 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription 106 chr8 54882952 54934685 CGC salivary TCERG1 10915 transcription elongation regulator 1 5q31 10393 15630 605409 "NP_006697;NP_001035095" "NM_006706;NM_001040006" "ENSP00000377943;ENSP00000296702" candidate 0 0 0 Eukaryotes 34 1 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription 87 chr5 145826913 145890202 WES colorectal (hypermutated) TCERG1L 256536 transcription elongation regulator 1-like 10q26.3 18170 23533 - NP_777597 NM_174937 ENSP00000357631 candidate 0 0 0 Eukaryotes 5 0 -1 -1 chr10 132891428 133109898 WES colorectal TCF12 6938 transcription factor 12 15q21 2725 11623 600480 "NP_003196;NP_996921;NP_996919;NP_996923;NP_996920" "NM_003205;NM_207038;NM_207036;NM_207040;NM_207037" "ENSP00000388940;ENSP00000331057;ENSP00000453737;ENSP00000342459" known 1 0 0 Metazoans 37 3 Cellular metabolism,DNA/RNA metabolism and transcription,Development,Regulation of intracellular processes and metabolism,Regulation of transcription 100 chr15 57212112 57574782 CGC sarcoma TCF3 6929 transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47) 19p13.3 918 11633 147141 "NP_003191;NP_001129611" "NM_003200;NM_001136139" "ENSP00000344375;ENSP00000262965" known 1 0 1 Eukaryotes 154 4 Cellular metabolism,DNA/RNA metabolism and transcription,Development,Immune system response,Regulation of intracellular processes and metabolism,Regulation of transcription 86 chr19 1611709 1650247 CGC leukemia TCF7L2 6934 transcription factor 7-like 2 (T-cell specific, HMG-box) 10q25.3 3751 11641 602228 "NP_001185456;NP_001139756;NP_001185459;NP_001185454;NP_110383;NP_001185455;NP_001139755;NP_001185460;NP_001185457;NP_001139746;NP_001139757;NP_001139758;NP_001185458" "NM_001198527;NM_001146284;NM_001198530;NM_001198525;NM_030756;NM_001198526;NM_001146283;NM_001198531;NM_001198528;NM_001146274;NM_001146285;NM_001146286;NM_001198529" "ENSP00000444972;ENSP00000347949;ENSP00000446238;ENSP00000446172;ENSP00000358404" known 1 0 0 Opisthokonts 31 0 Cell cycle,Cellular metabolism,Cellular processes,DNA/RNA metabolism and transcription,Development,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction 100 chr10 114710516 114925728 CGC,WES colorectal,colorectal (hypermutated),colorectal (non-hypermutated) TCL1A 8115 T-cell leukemia/lymphoma 1A 14q32.1 1744 11648 186960 "NP_068801;NP_001092195" "NM_021966;NM_001098725" "ENSP00000451506;ENSP00000385036" known 1 0 0 Mammals 7 4 -1 65 chr14 96178095 96180403 CGC leukemia TCL6 27004 T-cell leukemia/lymphoma 6 (non-protein coding) 14q32.1 5104 13463 604412 - "NM_012468;NM_020554;NM_020552;NM_020550;NM_014418;NM_020553;NR_028288" - known 1 0 -1 Primates 0 0 -1 24 - 0 0 CGC leukemia TCTEX1D4 343521 Tctex1 domain containing 4 1p34.1 15762 32315 611713 NP_001013654 NM_001013632 ENSP00000361274 candidate 0 0 0 Eukaryotes 5 0 -1 -1 chr1 45271678 45272340 WGS lymphoma TDG 6996 thymine-DNA glycosylase 12q24.1 3251 11700 601423 NP_003202 "NM_001008411;NM_003211" ENSP00000376611 candidate 0 0 1 Last Universal Common Ancestor 39 3 Cellular metabolism,DNA/RNA metabolism and transcription 71 chr12 104370694 104380865 HTMS breast,lung,ovarian,pancreas,prostate TDRD6 221400 tudor domain containing 6 6p12.3 18172 21339 611200 "NP_001010870;NP_001161831" "NM_001010870;NM_001168359" ENSP00000443299 candidate 0 0 0 Eukaryotes 2 0 -1 -1 chr6 46655866 46665824 WES breast TECTA 7007 tectorin alpha 11q22-q24 3985 11720 602574 NP_005413 NM_005422 ENSP00000264037 candidate 0 0 0 Eukaryotes 0 0 Cell motility and interactions,Cell response to stimuli 16 chr11 120973375 121061512 WES breast TERT 7015 telomerase reverse transcriptase 5p15.33 1754 11730 187270 "NP_937983;NP_001180305" "NM_198254;NM_198255;NM_198253;NM_001193376" "ENSP00000334346;ENSP00000309572" candidate 0 0 0 Eukaryotes 41 5 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism 14 chr5 1253846 1295104 WES lung TET1 80312 tet methylcytosine dioxygenase 1 10q21 9694 29484 607790 NP_085128 NM_030625 ENSP00000362748 known 1 0 0 Metazoans 1 4 -1 -1 chr10 70332096 70451568 CGC leukemia TET2 54790 tet methylcytosine dioxygenase 2 4q24 7876 25941 612839 "NP_001120680;NP_060098" "NM_001127208;NM_017628" "ENSP00000369351;ENSP00000306705" known 0 1 0 Metazoans 4 1 -1 -1 chr4 106155100 106197673 CGC,WES myelodysplasia TEX11 56159 testis expressed 11 Xq13.1 2256 11733 300311 "NP_001003811;NP_112566" "NM_001003811;NM_031276" "ENSP00000379226;ENSP00000363453" candidate 0 0 0 Eukaryotes 44 0 -1 5 chrX 69748948 70099960 WGS prostate TFAP2D 83741 transcription factor AP-2 delta (activating enhancer binding protein 2 delta) 6p12.1 11627 15581 610161 NP_758438 NM_172238 ENSP00000008391 candidate 0 0 0 Metazoans 0 0 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription -1 chr6 50682829 50740574 WES lung TFAP2E 339488 transcription factor AP-2 epsilon (activating enhancer binding protein 2 epsilon) 1p34.3 18174 30774 614428 NP_848643 NM_178548 ENSP00000362332 candidate 0 0 0 Metazoans 0 0 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription -1 chr1 36039528 36060274 WGS lymphoma TFE3 7030 transcription factor binding to IGHM enhancer 3 Xp11.22 2439 11752 314310 NP_006512 NM_006521 ENSP00000314129 known 1 0 0 Opisthokonts 56 1 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription 80 chrX 48887672 48900752 CGC kidney,sarcoma TFEB 7942 transcription factor EB 6p21 2847 11753 600744 "NP_001161299;NP_009093" "NM_001167827;NM_007162" "ENSP00000384203;ENSP00000230323" known 1 0 0 Opisthokonts 3 4 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription 52 chr6 41652340 41658951 CGC kidney TFG 10342 TRK-fused gene 3q12.2 3932 11758 602498 "NP_006061;NP_001007566;NP_001182408;NP_001182407" "NM_006070;NM_001007565;NM_001195479;NM_001195478" "ENSP00000419960;ENSP00000417952;ENSP00000240851" known 1 0 1 Eukaryotes 21 1 Cellular metabolism,Cellular processes,Regulation of intracellular processes and metabolism,Signal transduction 104 chr3 100432530 100467372 CGC lung,lymphoma,thyroid TFPT 29844 TCF3 (E2A) fusion partner (in childhood Leukemia) 19q13 10266 13630 609519 NP_037474 NM_013342 ENSP00000375639 known 1 0 0 Metazoans 35 1 -1 44 chr19 54610360 54618079 CGC leukemia TFRC 7037 transferrin receptor (p90, CD71) 3q29 1812 11763 190010 "NP_003225;NP_001121620" "NM_003234;NM_001128148" "ENSP00000353224;ENSP00000376197" known 1 0 0 Last Universal Common Ancestor 43 4 Cellular processes,Regulation of intracellular processes and metabolism 105 chr3 195778816 195802231 CGC non-hodgkin lymphoma TG 7038 thyroglobulin 8q24 1782 11764 188450 NP_003226 NM_003235 ENSP00000220616 candidate 0 0 0 Last Universal Common Ancestor 9 2 Cellular metabolism,Signal transduction 57 chr8 133879246 134147035 WES breast TGFBI 7045 transforming growth factor, beta-induced, 68kDa 5q31 3409 11771 601692 NP_000349 NM_000358 ENSP00000416330 candidate 0 0 0 Last Universal Common Ancestor 9 8 Cell motility and interactions,Cell response to stimuli,Regulation of intracellular processes and metabolism 87 chr5 135364745 135397268 WGS breast TGFBR2 7048 transforming growth factor, beta receptor II (70/80kDa) 3p22 1823 11773 190182 "NP_003233;NP_001020018" "NM_003242;NM_001024847" "ENSP00000351905;ENSP00000295754" candidate 0 0 0 Last Universal Common Ancestor 13 15 Cell cycle,Cellular metabolism,Cellular processes,Regulation of intracellular processes and metabolism,Signal transduction 106 chr3 30648376 30733088 WES colorectal,colorectal (hypermutated),pancreas TGM3 7053 transglutaminase 3 (E polypeptide, protein-glutamine-gamma-glutamyltransferase) 20q11.2 2584 11779 600238 NP_003236 NM_003245 ENSP00000370867 candidate 0 0 0 Metazoans 14 0 Cellular metabolism,Cellular processes,Development,Multicellular activities 46 chr20 2290302 2321224 WES colorectal THBS3 7059 thrombospondin 3 1q21 1767 11787 188062 "NP_001239536;NP_001239537;NP_009043" "NR_045553;NM_001252607;NM_001252608;NM_007112" "ENSP00000392207;ENSP00000357362" candidate 0 0 0 Last Universal Common Ancestor 1 1 Cell motility and interactions 47 chr1 155165635 155177667 WES breast THOC5 8563 THO complex 5 22q12.2 16650 19074 612733 "NP_001002878;NP_001002879;NP_003669;NP_001002877" "NM_001002878;NM_001002879;NM_003678;NM_001002877" "ENSP00000380971;ENSP00000380970;ENSP00000380969" candidate 0 0 0 Eukaryotes 7 1 -1 60 chr22 29904449 29945136 WES breast THRAP3 9967 thyroid hormone receptor associated protein 3 1p34.3 7543 22964 603809 NP_005110 NM_005119 ENSP00000346634 known 1 0 1 Eukaryotes 63 0 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction 5 chr1 36748165 36769615 CGC bone cyst THRSP 7069 thyroid hormone responsive 11q14.1 3566 11800 601926 NP_003242 NM_003251 ENSP00000281030 candidate 0 0 0 Vertebrates 0 0 -1 -1 chr11 77774928 77775365 WGS breast THSD7A 221981 thrombospondin, type I, domain containing 7A 7p21.3 - 22207 612249 NP_056019 NM_015204 - candidate 0 0 0 Last Universal Common Ancestor 4 0 -1 52 chr7 11415424 11871572 WES head and neck squamous cell carcinoma THSD7B 80731 thrombospondin, type I, domain containing 7B 2q22.1 - 29348 - NP_001073896 NM_001080427 ENSP00000413841 candidate 0 0 0 Last Universal Common Ancestor 1 0 -1 -1 chr2 137748462 138434172 WES prostate TIAM1 7074 T-cell lymphoma invasion and metastasis 1 21q22.1|21q22.11 2820 11805 600687 NP_003244 NM_003253 ENSP00000286827 candidate 0 0 0 Eukaryotes 33 3 Signal transduction 89 chr21 32492689 32639288 WES colorectal TIMELESS 8914 timeless homolog (Drosophila) 12q12-q13 4864 11813 603887 NP_003911 NM_003920 ENSP00000450607 candidate 0 0 0 Eukaryotes 20 0 Cell cycle,Cellular metabolism,DNA/RNA metabolism and transcription,Development,Regulation of intracellular processes and metabolism,Regulation of transcription 77 chr12 56811503 56827954 WES breast TKTL2 84076 transketolase-like 2 4q32.2 13159 25313 - NP_115512 NM_032136 ENSP00000280605 candidate 0 0 0 Last Universal Common Ancestor 2 1 -1 -1 chr4 164393009 164394886 WES lung TLE4 7091 transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila) 9q21.31 - 11840 605132 NP_008936 NM_007005 ENSP00000365703 candidate 0 0 1 Last Universal Common Ancestor 11 10 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction 84 chr9 82187706 82340056 WES acute myeloid leukemia TLL2 7093 tolloid-like 2 10q23-q24 5993 11844 606743 NP_036597 NM_012465 ENSP00000350630 candidate 0 0 1 Last Universal Common Ancestor 0 0 Cellular metabolism 20 chr10 98127848 98273442 WES lymphoma TLN1 7094 talin 1 9p13 1726 11845 186745 NP_006280 NM_006289 ENSP00000316029 candidate 0 0 1 Eukaryotes 44 3 Cell motility and interactions,Cellular processes 71 chr9 35697791 35725691 WES breast TLR2 7097 toll-like receptor 2 4q32 4323 11848 603028 NP_003255 NM_003264 - candidate 0 0 0 Eukaryotes 25 5 Cell cycle,Cell response to stimuli,Cellular processes,Development,Immune system response,Regulation of intracellular processes and metabolism,Signal transduction 19 chr4 154624060 154626411 WES chronic lymphocytic leukemia TLR4 7099 toll-like receptor 4 9q33.1 4325 11850 603030 "NP_612564;NP_003257;NP_612567" "NM_138554;NM_003266;NM_138557;NR_024168;NR_024169;NM_138556" ENSP00000363089 candidate 0 0 0 Eukaryotes 48 5 Cell response to stimuli,Cellular metabolism,Development,Immune system response,Regulation of intracellular processes and metabolism,Signal transduction 67 chr9 120466751 120476923 HTMS breast,lung,ovarian,pancreas,prostate TLR8 51311 toll-like receptor 8 Xp22 2296 15632 300366 NP_619542 "NM_016610;NM_138636" ENSP00000218032 candidate 0 0 0 Last Universal Common Ancestor 4 0 Cell response to stimuli,Cellular metabolism,Immune system response,Regulation of intracellular processes and metabolism,Signal transduction 4 chrX 12937163 12940282 WGS melanoma TLR9 54106 toll-like receptor 9 3p21.3 5685 15633 605474 NP_059138 "NM_138688;NM_017442" ENSP00000353874 candidate 0 0 0 Last Universal Common Ancestor 27 0 Cell response to stimuli,Cellular metabolism,Immune system response,Regulation of intracellular processes and metabolism,Signal transduction -1 chr3 52255236 52258328 WES colorectal TLX1 3195 T-cell leukemia homeobox 1 10q24 1728 5056 186770 "NP_001182446;NP_005512" "NM_001195517;NM_005521" ENSP00000434914 known 1 0 0 Eukaryotes 4 2 Cell cycle,Cellular metabolism,DNA/RNA metabolism and transcription,Development,Regulation of intracellular processes and metabolism,Regulation of transcription 1 chr10 102891299 102896667 CGC leukemia TLX3 30012 T-cell leukemia homeobox 3 5q35.1 6868 13532 604640 NP_066305 NM_021025 ENSP00000296921 known 1 0 0 Eukaryotes 2 2 Cell cycle,Cell motility and interactions,Cellular metabolism,DNA/RNA metabolism and transcription,Development,Regulation of intracellular processes and metabolism,Regulation of transcription 9 chr5 170736370 170738600 CGC,WGS leukemia,lymphoma TM6SF1 53346 transmembrane 6 superfamily member 1 15q24-q26 8411 11860 606562 "NP_075379;NP_001138375" "NM_023003;NM_001144903" ENSP00000317000 candidate 0 0 0 Eukaryotes 0 1 -1 65 chr15 83776433 83805421 WGS lymphoma,prostate TM7SF4 81501 transmembrane 7 superfamily member 4 8q23 7295 18549 605933 NP_110415 NM_030788 ENSP00000297581 candidate 0 0 0 Vertebrates 0 2 Development 40 chr8 105360781 105368423 WES pancreas TMEM123 114908 transmembrane protein 123 11q22.1 - 30138 606356 NP_443164 NM_052932 ENSP00000381204 candidate 0 0 0 Vertebrates 4 1 -1 106 chr11 102272272 102323354 WES breast TMEM132B 114795 transmembrane protein 132B 12q24.31 17230 29397 - NP_443139 NM_052907 - candidate 0 0 0 Eukaryotes 0 3 -1 -1 chr12 125811170 126139253 WES melanoma TMEM132D 121256 transmembrane protein 132D 12q24.33 13906 29411 611257 NP_597705 NM_133448 ENSP00000408581 candidate 0 0 0 Eukaryotes 2 0 -1 -1 chr12 129558423 130387884 WES lung TMEM30A 55754 transmembrane protein 30A 6q14.1 15535 16667 611028 "NP_001137430;NP_060717" "NM_001143958;NM_018247" ENSP00000230461 candidate 0 0 0 Eukaryotes 3 6 -1 97 chr6 75965821 75994354 WES lymphoma,non-hodgkin lymphoma TMPRSS2 7113 transmembrane protease, serine 2 21q22.3 3637 11876 602060 "NP_001128571;NP_005647" "NM_001135099;NM_005656" "ENSP00000381588;ENSP00000330330" known 1 0 0 Last Universal Common Ancestor 0 0 Cellular metabolism 35 chr21 42839661 42879931 CGC prostate TMPRSS6 164656 transmembrane protease, serine 6 22q12.3 10270 16517 609862 NP_705837 NM_153609 ENSP00000334962 candidate 0 0 0 Last Universal Common Ancestor 21 1 Cell motility and interactions,Cellular metabolism,Development,Multicellular activities,Signal transduction 63 chr22 37462123 37499460 WES breast TMSL3 7117 thymosin-like 3 4q22.1 10273 11885 - - NM_183049 - candidate 0 0 -1 Metazoans 0 0 Cellular metabolism,Cellular processes,Regulation of intracellular processes and metabolism 36 - 0 0 WES lymphoma TMTC2 160335 transmembrane and tetratricopeptide repeat containing 2 12q21.31 13230 25440 - NP_689801 NM_152588 ENSP00000322300 candidate 0 0 0 Last Universal Common Ancestor 1 6 -1 -1 chr12 83081366 83526165 WES chronic lymphocytic leukemia TMTC3 160418 transmembrane and tetratricopeptide repeat containing 3 12q21.32 10243 26899 - NP_861448 NM_181783 ENSP00000266712 candidate 0 0 0 Last Universal Common Ancestor 14 13 -1 -1 chr12 88542093 88589423 WES pancreas TMUB2 79089 transmembrane and ubiquitin-like domain containing 2 17q21.31 14542 28459 - "NP_803190;NP_001070142;NP_077012" "NM_177441;NM_001076674;NM_024107" "ENSP00000444565;ENSP00000350672;ENSP00000313214" candidate 0 0 0 Metazoans 1 4 Cellular metabolism,Cellular processes 69 chr17 42266388 42268229 WGS lung TNF 7124 tumor necrosis factor 6p21.3 1855 11892 191160 NP_000585 NM_000594 ENSP00000398698 candidate 0 0 0 Vertebrates 68 1 Cell cycle,Cell motility and interactions,Cell response to stimuli,Cellular metabolism,Cellular processes,DNA/RNA metabolism and transcription,Development,Immune system response,Multicellular activities,Other,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction 39 chr6 31543519 31545311 WES lymphoma TNFAIP3 7128 tumor necrosis factor, alpha-induced protein 3 6q23 1857 11896 191163 NP_006281 NM_006290 ENSP00000237289 known 0 1 0 Metazoans 64 3 Cell cycle,Development,Regulation of intracellular processes and metabolism,Signal transduction 104 chr6 138192365 138202453 CGC,WES lymphoma TNFRSF14 8764 tumor necrosis factor receptor superfamily, member 14 1p36.32 4122 11912 602746 NP_003811 NM_003820 ENSP00000347948 known 0 1 0 Metazoans 84 0 Cell cycle,Signal transduction 48 chr1 2488104 2494709 CGC,WES lymphoma,non-hodgkin lymphoma TNFRSF17 608 tumor necrosis factor receptor superfamily, member 17 16p13.1 144 11913 109545 NP_001183 NM_001192 ENSP00000053243 known 1 0 0 Mammals 9 1 Signal transduction 3 chr16 12059182 12061701 CGC lymphoma TNFRSF8 943 tumor necrosis factor receptor superfamily, member 8 1p36 1074 11923 153243 "NP_694421;NP_001234" "NM_152942;NM_001243" "ENSP00000263932;ENSP00000398337" candidate 0 0 0 Vertebrates 12 0 Cell cycle,Cellular metabolism,Development,Regulation of intracellular processes and metabolism,Signal transduction 65 chr1 12123656 12202585 WGS melanoma TNFSF10 8743 tumor necrosis factor (ligand) superfamily, member 10 3q26 4670 11925 603598 "NP_001177871;NP_003801;NP_001177872" "NM_001190942;NR_033994;NM_003810;NM_001190943" "ENSP00000389931;ENSP00000241261" candidate 0 0 0 Metazoans 23 3 Cell cycle,Development,Regulation of intracellular processes and metabolism,Signal transduction 79 chr3 172224285 172241174 WES melanoma TNFSF8 944 tumor necrosis factor (ligand) superfamily, member 8 9q33 4852 11938 603875 "NP_001239219;NP_001235" "NM_001252290;NM_001244" - candidate 0 0 0 Vertebrates 2 0 Cell cycle,Development,Regulation of intracellular processes and metabolism,Signal transduction 49 chr9 117666214 117692583 WES melanoma TNN 63923 tenascin N 1q23-q24 - 22942 - NP_071376 NM_022093 ENSP00000239462 candidate 0 0 0 Last Universal Common Ancestor 3 0 Cell cycle,Cell motility and interactions,Development,Signal transduction 38 chr1 175046555 175116204 WES colorectal,lung TNPO1 3842 transportin 1 5q13.2 4210 6401 602901 "NP_694858;NP_002261" "NM_153188;NM_002270" ENSP00000398524 candidate 0 0 3 Eukaryotes 41 9 Cellular processes 109 chr5 72144212 72201234 WGS melanoma TNR 7143 tenascin R (restrictin, janusin) 1q24 3589 11953 601995 NP_003276 NM_003285 ENSP00000356646 candidate 0 0 0 Eukaryotes 9 0 Cell cycle,Cell motility and interactions,Development,Signal transduction 44 chr1 175292496 175375850 WES,WGS pancreas,prostate TOP1 7150 topoisomerase (DNA) I 20q12-q13.1 535 11986 126420 NP_003277 NM_003286 ENSP00000354522 known 1 0 0 Last Universal Common Ancestor 158 5 Cell cycle,Cellular metabolism,DNA/RNA metabolism and transcription 104 chr20 39690033 39751934 CGC leukemia TP53 7157 tumor protein p53 17p13.1 1859 11998 191170 "NP_001119587;NP_001119586;NP_001119584;NP_001119589;NP_001119588;NP_000537;NP_001119585;NP_001119590" "NM_001126115;NM_001126114;NM_001126112;NM_001126117;NM_001126116;NM_000546;NM_001126113;NM_001126118" "ENSP00000269305;ENSP00000391478;ENSP00000398846;ENSP00000391127" known 0 1 0 Eukaryotes 741 16 Cell cycle,Cell response to stimuli,Cellular metabolism,Cellular processes,DNA/RNA metabolism and transcription,Development,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction 70 chr17 7572930 7579912 CGC,HTMS,WES,WGS adrenocortical,breast,colorectal,glioma,lung,other,sarcoma,glioblastoma,ovarian,pancreas,prostate,bladder,cholangiocarcinoma,chronic lymphocytic leukemia,colorectal (non-hypermutated),endometrium,gastric,head and neck squamous cell carcinoma,kidney,liver,lymphoma,medulloblastoma,myelodysplasia,myeloma,non-hodgkin lymphoma TP53INP1 94241 tumor protein p53 inducible nuclear protein 1 8q22 9367 18022 606185 "NP_150601;NP_001129205" "NM_033285;NM_001135733" "ENSP00000390063;ENSP00000344215" candidate 0 0 0 Metazoans 3 9 Cell cycle -1 chr8 95942710 95953169 WES acute myeloid leukemia TP63 8626 tumor protein p63 3q28 4469 15979 603273 "NP_003713;NP_001108451;NP_001108454;NP_001108453;NP_001108450;NP_001108452" "NM_003722;NM_001114979;NM_001114982;NM_001114981;NM_001114978;NM_001114980" "ENSP00000407144;ENSP00000346614;ENSP00000392488;ENSP00000264731" candidate 0 0 0 Eukaryotes 77 8 Cell cycle,Cellular metabolism,DNA/RNA metabolism and transcription,Development,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction 90 chr3 189349305 189612288 WES,WGS head and neck squamous cell carcinoma,melanoma TPM3 7170 tropomyosin 3 1q21.2 1840 12012 191030 "NP_705935;NP_689476;NP_001036816;NP_001036817;NP_001036818" "NM_153649;NM_152263;NM_001043351;NM_001043352;NM_001043353" ENSP00000357521 known 1 0 2 Metazoans 47 6 Multicellular activities 42 chr1 154141783 154164494 CGC lung,lymphoma,thyroid TPM4 7171 tropomyosin 4 19p13.1 11734 12013 600317 "NP_003281;NP_001138632" "NM_003290;NM_001145160" ENSP00000300933 known 1 0 5 Metazoans 4 4 -1 87 chr19 16178435 16212153 CGC lymphoma TPO 7173 thyroid peroxidase 2p25 6000 12015 606765 "NP_783653;NP_783652;NP_001193674;NP_001193673;NP_000538;NP_783650" "NM_175720;NM_175722;NM_175721;NM_001206745;NM_001206744;NM_000547;NM_175719" "ENSP00000318820;ENSP00000329869;ENSP00000371636;ENSP00000263886;ENSP00000371633" candidate 0 0 0 Last Universal Common Ancestor 2 2 Cell response to stimuli,Cellular metabolism 9 chr2 1418181 1546243 WES pancreas TPR 7175 translocated promoter region (to activated MET oncogene) 1q25 8927 12017 189940 NP_003283 NM_003292 - known 1 0 0 Last Universal Common Ancestor 66 1 Cellular metabolism,Cellular processes,DNA/RNA metabolism and transcription,Regulation of transcription 107 chr1 186283106 186344160 CGC thyroid TPRX1 284355 tetra-peptide repeat homeobox 1 19q13.33 13447 32174 611166 NP_940881 NM_198479 ENSP00000323455 candidate 0 0 0 Primates 0 0 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription -1 chr19 48305035 48306240 WGS lymphoma TRA@ 6955 T cell receptor alpha locus 14q11.2 - 12027 186880 - - - known 1 0 -1 Vertebrates 30 0 Cell response to stimuli 97 - 0 0 CGC,WGS leukemia,glioblastoma TRABD 80305 TraB domain containing 22q13.33 11450 28805 - NP_079480 NM_025204 ENSP00000305664 candidate 0 0 0 Last Universal Common Ancestor 3 1 -1 1 chr22 50632005 50636945 WGS lymphoma TRAF3 7187 TNF receptor-associated factor 3 14q32.32 3539 12033 601896 "NP_001186356;NP_663777;NP_663778;NP_003291" "NM_001199427;NM_145725;NM_145726;NM_003300" ENSP00000454207 candidate 0 0 0 Eukaryotes 102 1 Cell cycle,Development,Regulation of intracellular processes and metabolism,Signal transduction 69 chr14 103336539 103372118 WES lymphoma TRAF5 7188 TNF receptor-associated factor 5 1q32 3834 12035 602356 "NP_001029082;NP_004610;NP_665702" "NM_001033910;NM_004619;NM_145759" "ENSP00000261464;ENSP00000336825" candidate 0 0 0 Eukaryotes 63 0 Cell cycle,Regulation of intracellular processes and metabolism,Signal transduction 52 chr1 211526582 211546041 HTMS breast,lung,ovarian,pancreas,prostate TRAPPC10 7109 trafficking protein particle complex 10 21q22.3 3656 11868 602103 NP_003265 "NM_001001723;NM_003274" ENSP00000291574 candidate 0 0 0 Eukaryotes 14 1 Cellular processes 69 chr21 45432375 45523409 WGS melanoma TRB@ 6957 T cell receptor beta locus 7q34 - 12155 186930 - - - known 1 0 -1 - 0 0 -1 -1 - 0 0 CGC,WGS leukemia,melanoma TRD@ 6964 T cell receptor delta locus 14q11.2 - 12252 186810 - - - known 1 0 -1 - 4 0 -1 20 - 0 0 CGC leukemia TRIB1 10221 tribbles homolog 1 (Drosophila) 8q24.13 9863 16891 609461 NP_079471 NM_025195 ENSP00000312150 known 0 0 0 Last Universal Common Ancestor 23 5 Cell cycle,Cell motility and interactions,Cell response to stimuli,Cellular metabolism,Cellular processes,DNA/RNA metabolism and transcription,Development,Multicellular activities,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction 90 chr8 126443145 126448710 CGC,Amplified TRIM11 81559 tripartite motif containing 11 1q42.13 7429 16281 607868 NP_660215 NM_145214 ENSP00000284551 candidate 0 0 0 Eukaryotes 18 0 -1 -1 chr1 228582409 228594262 HTMS breast,lung,ovarian,pancreas,prostate TRIM24 8805 tripartite motif containing 24 7q32-q34 4556 11812 603406 "NP_003843;NP_056989" "NM_003852;NM_015905" ENSP00000390829 known 1 0 0 Eukaryotes 75 4 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription 83 chr7 138145294 138269693 CGC leukemia TRIM27 5987 tripartite motif containing 27 6p22 15996 9975 602165 NP_006501 "NM_030950;NM_006510" ENSP00000366404 known 1 0 0 Eukaryotes 116 0 Cellular metabolism,DNA/RNA metabolism and transcription,Development,Multicellular activities,Regulation of intracellular processes and metabolism,Regulation of transcription 106 chr6 28871850 28891409 CGC thyroid TRIM33 51592 tripartite motif containing 33 1p13.1 10423 16290 605769 "NP_148980;NP_056990" "NM_033020;NM_015906" ENSP00000351250 known 1 0 0 Eukaryotes 65 3 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription 82 chr1 114940273 115053697 CGC thyroid TRIM37 4591 tripartite motif containing 37 17q23.2 5463 7523 605073 "NP_001005207;NP_056109" "NM_001005207;NM_015294" "ENSP00000376785;ENSP00000262294" candidate 0 0 0 Eukaryotes 60 3 -1 75 chr17 57076741 57181755 HTMS breast,lung,ovarian,pancreas,prostate TRIM55 84675 tripartite motif containing 55 8q13.1 5927 14215 606469 "NP_149047;NP_908975;NP_908973;NP_908974" "NM_033058;NM_184087;NM_184085;NM_184086" "ENSP00000323913;ENSP00000297348" candidate 0 0 0 Eukaryotes 70 0 Signal transduction -1 chr8 67039504 67086825 WGS prostate TRIOBP 11078 TRIO and F-actin binding protein 22q13.1 11028 17009 609761 "NP_619538;NP_008963;NP_001034230" "NM_138632;NM_007032;NM_001039141" "ENSP00000384312;ENSP00000383913" candidate 0 0 0 Last Universal Common Ancestor 9 1 Cell response to stimuli,Cellular metabolism,Cellular processes,Regulation of intracellular processes and metabolism 106 chr22 38097373 38168766 WES breast TRIP11 9321 thyroid hormone receptor interactor 11 14q31-q32 5143 12305 604505 NP_004230 NM_004239 ENSP00000267622 known 1 0 0 Last Universal Common Ancestor 15 3 Cellular metabolism,DNA/RNA metabolism and transcription 61 chr14 92436020 92506029 CGC leukemia TRO 7216 trophinin Xp11.22-p11.21 2134 12326 300132 "NP_001034794;NP_808224;NP_057241" "NM_001039705;NM_177556;NM_177555;NM_016157;NM_177558;NM_177557" "ENSP00000173898;ENSP00000405126;ENSP00000364181;ENSP00000318278;ENSP00000364162;ENSP00000382641" candidate 0 0 0 Last Universal Common Ancestor 14 0 Cell motility and interactions,Development 51 chrX 54948680 54957450 WES chronic lymphocytic leukemia TRPM1 4308 transient receptor potential cation channel, subfamily M, member 1 15q13.3 4656 7146 603576 "NP_002411;NP_001238959;NP_001238953;NP_001238949" "NM_002420;NM_001252030;NM_001252024;NM_001252020" "ENSP00000437849;ENSP00000256552;ENSP00000453851;ENSP00000380897" candidate 0 0 0 Eukaryotes 1 1 Cellular processes 19 chr15 31294028 31453162 WGS glioblastoma TRPM6 140803 transient receptor potential cation channel, subfamily M, member 6 9q21.13 6112 17995 607009 "NP_001170781;NP_060132;NP_001170782" "NM_001177310;NM_017662;NM_001177311" "ENSP00000396672;ENSP00000354962;ENSP00000354006" candidate 0 0 0 Eukaryotes 4 2 Cellular metabolism,Cellular processes 16 chr9 77339532 77473664 WGS chronic lymphocytic leukemia TRPV4 59341 transient receptor potential cation channel, subfamily V, member 4 12q24.1 5667 18083 605427 "NP_671737;NP_001170899;NP_001170904;NP_067638;NP_001170902" "NM_147204;NM_001177428;NM_001177433;NM_021625;NM_001177431" "ENSP00000442167;ENSP00000444336;ENSP00000443611;ENSP00000261740;ENSP00000442738" candidate 0 0 0 Eukaryotes 21 1 Cellular processes,Regulation of intracellular processes and metabolism,Signal transduction 29 chr12 110221429 110252601 WGS chronic lymphocytic leukemia TRPV5 56302 transient receptor potential cation channel, subfamily V, member 5 7q35 5981 3145 606679 NP_062815 NM_019841 ENSP00000265310 candidate 0 0 1 Eukaryotes 10 0 Cellular metabolism,Cellular processes 33 chr7 142605683 142630556 WES glioblastoma TRRAP 8295 transformation/transcription domain-associated protein 7q21.2-q22.1 4310 12347 603015 "NP_003487;NP_001231509" "NM_003496;NM_001244580" "ENSP00000352925;ENSP00000347733" candidate 0 0 0 Eukaryotes 77 5 Cellular metabolism,Cellular processes,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction 90 chr7 98478774 98609975 WGS liver TSC1 7248 tuberous sclerosis 1 9q34 5594 12362 605284 "NP_001155898;NP_000359;NP_001155899" "NM_001162426;NM_000368;NM_001008567;NM_001162427" "ENSP00000298552;ENSP00000444017" known 0 1 0 Opisthokonts 57 2 Cell cycle,Cell motility and interactions,Cell response to stimuli,Cellular metabolism,Cellular processes,DNA/RNA metabolism and transcription,Development,Multicellular activities,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction 98 chr9 135771625 135804259 CGC,WES,WGS kidney,liver TSC2 7249 tuberous sclerosis 2 16p13.3 1850 12363 191092 "NP_001070651;NP_001107854;NP_000539" "NM_001077183;NM_001114382;NM_021055;NM_021056;NM_000548" "ENSP00000219476;ENSP00000384468;ENSP00000344383" known 0 1 0 Eukaryotes 62 0 Cell cycle,Cell motility and interactions,Cellular processes,Development,Regulation of intracellular processes and metabolism,Signal transduction 67 chr16 2098617 2138608 CGC,WES pancreas TSC22D1 8848 TSC22 domain family, member 1 13q14 7414 16826 607715 "NP_006013;NP_001230726;NP_904358;NP_001230727;NP_001230728" "NM_006022;NM_001243797;NM_183422;NM_001243798;NM_001243799" - candidate 0 0 0 Metazoans 190 0 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription 101 chr13 45008765 45150210 WES lymphoma TSHR 7253 thyroid stimulating hormone receptor 14q31 4537 12373 603372 "NP_001018046;NP_000360;NP_001136098" "NM_001018036;NM_000369;NM_001142626" "ENSP00000298171;ENSP00000340113;ENSP00000450549" known 1 0 0 Metazoans 24 5 Cell cycle,Regulation of intracellular processes and metabolism,Signal transduction 10 chr14 81422025 81610694 CGC thyroid TSHZ2 128553 teashirt zinc finger homeobox 2 20q13.2 10730 13010 614118 "NP_775756;NP_001180350" "NM_173485;NM_001193421" - candidate 0 0 0 Eukaryotes 3 0 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription 46 chr20 51589833 51873099 WGS chronic lymphocytic leukemia TSPEAR 54084 thrombospondin-type laminin G domain and EAR repeats 21q22.3 9845 1268 612920 NP_659428 NM_144991 ENSP00000321987 candidate 0 0 0 Eukaryotes 6 0 -1 -1 chr21 45919669 46131429 WES glioblastoma TTBK1 84630 tau tubulin kinase 1 6p21.1 11653 19140 - NP_115927 NM_032538 ENSP00000259750 candidate 0 0 0 Last Universal Common Ancestor 8 0 Cellular metabolism,Cellular processes -1 chr6 43214399 43253111 WGS melanoma TTBK2 146057 tau tubulin kinase 2 15q15.2 10288 19141 611695 NP_775771 NM_173500 - candidate 0 0 0 Last Universal Common Ancestor 17 0 Cellular metabolism,Cellular processes 45 chr15 43037996 43170815 WGS lung TTC18 118491 tetratricopeptide repeat domain 18 10q22.2 15583 30726 - NP_660153 NM_145170 ENSP00000310829 candidate 0 0 0 Eukaryotes 0 1 -1 -1 chr10 75013736 75114554 WES lymphoma TTC40 54777 tetratricopeptide repeat domain 40 10q26.3 12596 25247 - "NP_001186978;XP_003119525;NP_775843;XP_003118674" "NM_001200049;XM_003119477;NM_017609;NM_173572;XM_003118626" ENSP00000357575 candidate 0 0 0 - 0 0 -1 29 chr10 134621928 134755988 WGS glioblastoma TTK 7272 TTK protein kinase 6q13-q21 4973 12401 604092 "NP_001160163;NP_003309" "NM_001166691;NM_003318" "ENSP00000230510;ENSP00000358813" candidate 0 0 0 Last Universal Common Ancestor 23 4 Cell cycle,Cellular metabolism,Cellular processes,Regulation of intracellular processes and metabolism 24 chr6 80715561 80751916 WES gastric TTL 150465 tubulin tyrosine ligase 2q13 12206 21586 608291 NP_714923 NM_153712 ENSP00000233336 known 1 0 0 Eukaryotes 1 0 Cell cycle,Cellular metabolism,Cellular processes,Development,Regulation of intracellular processes and metabolism -1 chr2 113239922 113286369 CGC leukemia TTLL6 284076 tubulin tyrosine ligase-like family, member 6 17q21.32 8763 26664 610849 "NP_775894;NP_001124390" "NM_173623;NM_001130918" "ENSP00000377043;ENSP00000399211" candidate 0 0 0 Eukaryotes 1 0 Cellular metabolism,Cellular processes -1 chr17 46846354 46894434 WGS melanoma TTN 7273 titin 2q31 1787 12403 188840 "NP_597681;NP_596870;NP_596869;NP_597676;NP_003310" "NM_133437;NM_133379;NM_133378;NM_133432;NM_003319" "ENSP00000465570;ENSP00000467141;ENSP00000434586;ENSP00000343764;ENSP00000354117;ENSP00000352154;ENSP00000340554" candidate 0 0 0 Last Universal Common Ancestor 118 0 Cell cycle,Cellular metabolism,Cellular processes,Development,Multicellular activities,Signal transduction 62 chr2 179576672 179669369 WES,WGS colorectal (non-hypermutated),gastric,lung TUBA3C 7278 tubulin, alpha 3c 13q11 3958 12408 602528 NP_005992 "NM_006001;NM_079836" - candidate 0 0 16 Eukaryotes 22 0 Cellular metabolism,Cellular processes 34 chr13 19748006 19753703 WES lung TUBA8 51807 tubulin, alpha 8 22q11.1 5763 12410 605742 "NP_001180343;NP_061816" "NM_001193414;NM_018943" ENSP00000333326 candidate 0 0 14 Eukaryotes 11 2 Cellular metabolism,Cellular processes 16 chr22 18604246 18613900 WGS lymphoma TUBAL3 79861 tubulin, alpha-like 3 10p15.1 8640 23534 - "NP_001165335;NP_079079" "NM_001171864;NM_024803" "ENSP00000418799;ENSP00000369784" candidate 0 0 9 Eukaryotes 16 2 Cellular metabolism,Cellular processes 25 chr10 5435483 5443050 WGS prostate TUBB 203068 tubulin, beta class I 6p21.33 - 20778 191130 NP_821133 NM_178014 ENSP00000339001 candidate 0 0 23 Eukaryotes 188 2 Cell cycle,Cellular metabolism,Cellular processes,Development,Immune system response,Regulation of intracellular processes and metabolism 109 chr6 30688284 30692171 WGS lymphoma TYSND1 219743 trypsin domain containing 1 10q22.1 15593 28531 611017 "NP_001035363;NP_775826" "NM_001040273;NM_173555" "ENSP00000335673;ENSP00000287078" candidate 0 0 0 Eukaryotes 2 1 Cellular metabolism -1 chr10 71899683 71906342 WES pancreas U2AF1 7307 U2 small nuclear RNA auxiliary factor 1 21q22.3 1871 12453 191317 "NP_001020374;NP_001020375;NP_006749" "NM_001025203;NM_001025204;NM_006758" "ENSP00000369629;ENSP00000381205;ENSP00000291552" known 1 0 2 Eukaryotes 30 0 DNA/RNA metabolism and transcription,Regulation of transcription 88 chr21 44513215 44527604 CGC,WES leukemia,myelodysplasia U2AF2 11338 U2 small nuclear RNA auxiliary factor 2 19q13.42 1872 23156 191318 "NP_001012496;NP_009210" "NM_001012478;NM_007279" ENSP00000388475 candidate 0 0 0 Eukaryotes 48 0 DNA/RNA metabolism and transcription,Regulation of transcription 105 chr19 56166471 56185431 WES chronic lymphocytic leukemia UBB 7314 ubiquitin B 17p12-p11.2 6771 12463 191339 NP_061828 NM_018955 - candidate 0 0 17 Last Universal Common Ancestor 160 1 Cell cycle,Cell motility and interactions,Cellular metabolism,Cellular processes,DNA/RNA metabolism and transcription,Development,Multicellular activities,Regulation of intracellular processes and metabolism,Regulation of transcription 36 chr17 16285222 16285908 WES melanoma UBE2A 7319 ubiquitin-conjugating enzyme E2A Xq24 2422 12472 312180 "NP_861442;NP_003327;NP_861427" "NM_181777;NM_003336;NM_181762" "ENSP00000360613;ENSP00000360624" candidate 0 0 1 Eukaryotes 64 0 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism 107 chrX 118708675 118717215 WES lymphoma UBE2D1 7321 ubiquitin-conjugating enzyme E2D 1 10q21.1 4267 12474 602961 "NP_003329;NP_001191809" "NM_003338;NM_001204880" - candidate 0 0 4 Eukaryotes 99 4 Cellular metabolism,Cellular processes,Regulation of intracellular processes and metabolism,Signal transduction 64 chr10 60121098 60128522 WES melanoma UBE2G2 7327 ubiquitin-conjugating enzyme E2G 2 21q22.3 4387 12483 603124 "NP_872630;NP_001189418;NP_003334" "NM_182688;NM_001202489;NM_003343" ENSP00000338348 candidate 0 0 0 Eukaryotes 52 0 Cellular metabolism,Cellular processes,Regulation of intracellular processes and metabolism 76 chr21 46191295 46207881 WGS breast UBE2O 63893 ubiquitin-conjugating enzyme E2O 17q25.1 10928 29554 - NP_071349 NM_022066 ENSP00000323687 candidate 0 0 0 Eukaryotes 58 1 Regulation of intracellular processes and metabolism 20 chr17 74387027 74449223 WGS prostate UBQLNL 143630 ubiquilin-like 11p15.4 14472 28294 - NP_659490 NM_145053 ENSP00000369531 candidate 0 0 0 Eukaryotes 0 0 Cellular metabolism,Cellular processes -1 chr11 5536247 5537671 WES colorectal UBR1 197131 ubiquitin protein ligase E3 component n-recognin 1 15q13 9342 16808 605981 NP_777576 NM_174916 ENSP00000290650 candidate 0 0 0 Eukaryotes 67 1 Cellular metabolism -1 chr15 43237530 43398220 WGS lung UBR3 130507 ubiquitin protein ligase E3 component n-recognin 3 (putative) 2q31.1 15887 30467 613831 NP_742067 NM_172070 ENSP00000396068 candidate 0 0 0 Eukaryotes 4 2 Cell response to stimuli,Cellular metabolism,Multicellular activities -1 chr2 170684018 170938350 WGS liver UBR5 51366 ubiquitin protein ligase E3 component n-recognin 5 8q22 6436 16806 608413 NP_056986 NM_015902 ENSP00000429084 candidate 0 0 0 Metazoans 76 5 Cellular metabolism,Cellular processes,Signal transduction 106 chr8 103266533 103424462 HTMS,WES breast,lung,ovarian,pancreas,prostate,colorectal UGGT1 56886 UDP-glucose glycoprotein glucosyltransferase 1 2q14.3 12064 15663 605897 NP_064505 "NM_020120;NM_001025777;NR_027671" ENSP00000259253 candidate 0 0 0 Eukaryotes 29 4 Cellular metabolism,Cellular processes 38 chr2 128848932 128945190 WGS lymphoma UGT2B10 7365 UDP glucuronosyltransferase 2 family, polypeptide B10 4q13.2 7193 12544 600070 "NP_001138239;NP_001066" "NM_001144767;NM_001075" - candidate 0 0 9 Last Universal Common Ancestor 1 0 -1 -1 chr4 69681738 69696594 WES melanoma UGT2B11 10720 UDP glucuronosyltransferase 2 family, polypeptide B11 4q13.2 4345 12545 603064 NP_001064 NM_001073 ENSP00000387683 candidate 0 0 10 Last Universal Common Ancestor 0 0 Cellular metabolism -1 chr4 70066161 70080440 WGS chronic lymphocytic leukemia UHRF2 115426 ubiquitin-like with PHD and ring finger domains 2 9p24.1 18257 12557 - NP_690856 NM_152896 ENSP00000276893 candidate 0 0 1 Last Universal Common Ancestor 62 5 Cell cycle,Cellular metabolism,Cellular processes -1 chr9 6413491 6506176 WES colorectal UNC119B 84747 unc-119 homolog B (C. elegans) 12q24.31 - 16488 - NP_001074002 "NM_032661;NM_001080533" ENSP00000344942 candidate 0 0 0 Eukaryotes 3 2 -1 91 chr12 121148278 121157832 WGS chronic lymphocytic leukemia UNC13C 440279 unc-13 homolog C (C. elegans) 15q21.3 - 23149 - NP_001074003 NM_001080534 ENSP00000260323 candidate 0 0 0 Eukaryotes 5 2 Cellular processes,Signal transduction -1 chr15 54305101 54919308 WES chronic lymphocytic leukemia,pancreas UNC5C 8633 unc-5 homolog C (C. elegans) 4q21-q23 4678 12569 603610 NP_003719 NM_003728 ENSP00000406022 candidate 0 0 0 Metazoans 2 1 Cell cycle,Cell motility and interactions,Development,Signal transduction 15 chr4 96090388 96470008 WES lymphoma UNC5D 137970 unc-5 homolog D (C. elegans) 8p12 11661 18634 - NP_543148 NM_080872 ENSP00000394303 candidate 0 0 0 Metazoans 0 3 Cell cycle,Signal transduction -1 chr8 35093303 35648078 WES chronic lymphocytic leukemia,lymphoma UNC79 57578 unc-79 homolog (C. elegans) 14q32.12 11143 19966 - NP_065869 NM_020818 ENSP00000256339 candidate 0 0 0 Metazoans 62 3 -1 -1 chr14 93943987 94173247 WES colorectal UNC80 285175 unc-80 homolog (C. elegans) 2q35 12809 26582 612636 "NP_115893;NP_872393" "NM_032504;NM_182587" ENSP00000391088 candidate 0 0 0 Opisthokonts 6 0 -1 -1 chr2 210636797 210860316 WES chronic lymphocytic leukemia UQCRC2 7385 ubiquinol-cytochrome c reductase core protein II 16p12 1876 12586 191329 NP_003357 NM_003366 ENSP00000456232 candidate 0 0 0 Last Universal Common Ancestor 30 2 Cellular metabolism 109 chr16 21968556 21994489 WES colorectal UQCRFS1 7386 ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1 19q12 1874 12587 191327 NP_005994 NM_006003 - candidate 0 0 1 Last Universal Common Ancestor 36 0 -1 109 chr19 29698458 29704025 WGS melanoma URB2 9816 URB2 ribosome biogenesis 2 homolog (S. cerevisiae) 1q42.13 17178 28967 - NP_055592 NM_014777 ENSP00000258243 candidate 0 0 0 Eukaryotes 2 2 -1 19 chr1 229763381 229795041 WES glioblastoma USH2A 7399 Usher syndrome 2A (autosomal recessive, mild) 1q41 9759 12601 608400 "NP_996816;NP_009054" "NM_206933;NM_007123" "ENSP00000355909;ENSP00000305941" candidate 0 0 0 Last Universal Common Ancestor 2 4 Cell response to stimuli,Development,Regulation of intracellular processes and metabolism 13 chr1 215799126 216595678 WES breast,head and neck squamous cell carcinoma,pancreas USP16 10600 ubiquitin specific peptidase 16 21q22.11 6881 12614 604735 "NP_006438;NP_001027582;NP_001001992" "NM_006447;NM_001032410;NM_001001992" "ENSP00000382857;ENSP00000334808;ENSP00000382858" candidate 0 0 0 Eukaryotes 15 0 Cellular metabolism 100 chr21 30400235 30426505 HTMS breast,lung,ovarian,pancreas,prostate USP18 11274 ubiquitin specific peptidase 18 22q11.21 6136 12616 607057 NP_059110 NM_017414 ENSP00000215794 candidate 0 0 1 Eukaryotes 7 3 Cellular metabolism 10 chr22 18640431 18659581 HTMS breast,lung,ovarian,pancreas,prostate USP21 27005 ubiquitin specific peptidase 21 1q22 5291 12620 604729 "NP_036607;NP_001014443" "NM_012475;NM_001014443" "ENSP00000356981;ENSP00000289865" candidate 0 0 0 Eukaryotes 56 2 Cellular metabolism,Cellular processes 94 chr1 161130431 161135234 HTMS breast,lung,ovarian,pancreas,prostate USP25 29761 ubiquitin specific peptidase 25 21q11.2 5296 12624 604736 NP_037528 NM_013396 ENSP00000285681 candidate 0 0 0 Eukaryotes 44 5 Cellular metabolism,Cellular processes 103 chr21 17102713 17250791 WGS liver USP26 83844 ubiquitin specific peptidase 26 Xq26.2 2255 13485 300309 NP_114113 NM_031907 - candidate 0 0 0 Eukaryotes 4 0 Cellular metabolism -1 chrX 132159510 132162248 WGS liver USP28 57646 ubiquitin specific peptidase 28 11q23 15632 12625 610748 NP_065937 NM_020886 ENSP00000003302 candidate 0 0 0 Eukaryotes 47 3 Cellular metabolism -1 chr11 113669965 113746223 WGS breast USP29 57663 ubiquitin specific peptidase 29 19q13.43 7163 18563 609546 NP_065954 NM_020903 ENSP00000254181 candidate 0 0 0 Eukaryotes 3 1 Cellular metabolism,Cellular processes 29 chr19 57640044 57642809 HTMS breast,lung,ovarian,pancreas,prostate USP40 55230 ubiquitin specific peptidase 40 2q37.1 7166 20069 610570 NP_060688 NM_018218 ENSP00000415434 candidate 0 0 0 Eukaryotes 3 0 Cellular metabolism -1 chr2 234386041 234474236 WGS prostate USP6 9098 ubiquitin specific peptidase 6 (Tre-2 oncogene) 17p13 6827 12629 604334 NP_004496 "NM_004505;NM_005152" ENSP00000250066 known 1 0 0 Eukaryotes 14 1 Cellular metabolism,Cellular processes,Regulation of intracellular processes and metabolism,Signal transduction 77 chr17 5033663 5076270 CGC bone cyst UTP20 27340 UTP20, small subunit (SSU) processome component, homolog (yeast) 12q23 9928 17897 612822 NP_055318 NM_014503 ENSP00000261637 candidate 0 0 0 Eukaryotes 13 3 Cell cycle,Regulation of intracellular processes and metabolism 55 chr12 101674061 101779898 WES pancreas UTY 7404 ubiquitously transcribed tetratricopeptide repeat gene, Y-linked Yq11 2451 12638 400009 "NP_872600;NP_009056;NP_872601" "NM_182659;NM_007125;NM_182660" "ENSP00000328939;ENSP00000355420;ENSP00000330446" candidate 0 0 1 Last Universal Common Ancestor 5 0 DNA/RNA metabolism and transcription 47 chrY 15362897 15591545 WES bladder UVRAG 7405 UV radiation resistance associated gene 11q13.5 3929 12640 602493 NP_003360 NM_003369 - candidate 0 0 0 Eukaryotes 52 3 DNA/RNA metabolism and transcription 81 chr11 75526453 75852454 WGS lung VANGL1 81839 vang-like 1 (van gogh, Drosophila) 1p13.1 18279 15512 610132 "NP_001165882;NP_001165883;NP_620409" "NM_001172411;NM_001172412;NM_138959" ENSP00000347672 candidate 0 0 0 Metazoans 11 7 -1 51 chr1 116194035 116233997 WES neuroblastoma VCAN 1462 versican 5q14.3 340 2464 118661 "NP_001157570;NP_004376;NP_001157569;NP_001119808" "NM_001164098;NM_004385;NM_001164097;NM_001126336" "ENSP00000340062;ENSP00000342768;ENSP00000265077" candidate 0 0 0 Last Universal Common Ancestor 27 0 -1 100 chr5 82779338 82876250 WGS melanoma VCX3B 425054 variable charge, X-linked 3B Xp22.31 15646 31838 - NP_001001888 NM_001001888 ENSP00000370420 candidate 0 0 2 Primates 0 0 Development,Multicellular activities -1 chrX 8433492 8434421 WGS melanoma VEPH1 79674 ventricular zone expressed PH domain homolog 1 (zebrafish) 3q24-q25 7782 25735 609594 "NP_001161388;NP_001161387;NP_078897;NP_001161389;NP_001161383;NP_001161384" "NM_001167916;NM_001167915;NM_024621;NM_001167917;NM_001167911;NM_001167912" "ENSP00000376578;ENSP00000354919;ENSP00000419193;ENSP00000417268;ENSP00000443868" candidate 0 0 0 Metazoans 7 0 -1 -1 chr3 156978926 157213138 WES breast VHL 7428 von Hippel-Lindau tumor suppressor 3p25.3 1905 12687 608537 "NP_000542;NP_937799" "NM_000551;NM_198156" - known 0 1 1 Metazoans 433 4 Cell cycle,Cellular metabolism,Cellular processes,DNA/RNA metabolism and transcription,Development,Regulation of intracellular processes and metabolism,Regulation of transcription 11 chr3 10183532 10191646 CGC,WES hemangioma,kidney,pheochromocytoma VILL 50853 villin-like 3p21.3 18283 30906 - NP_056957 NM_015873 ENSP00000373266 candidate 0 0 0 Eukaryotes 0 1 Cellular metabolism,Cellular processes,Regulation of intracellular processes and metabolism 23 chr3 38035164 38048543 WES chronic lymphocytic leukemia VIPR2 7434 vasoactive intestinal peptide receptor 2 7q36.3 3576 12695 601970 NP_003373 NM_003382 ENSP00000262178 candidate 0 0 0 Vertebrates 1 0 Signal transduction 20 chr7 158823310 158937463 WGS lung VN1R4 317703 vomeronasal 1 receptor 4 19q13.42 18287 19871 - NP_776256 NM_173857 ENSP00000310856 candidate 0 0 1 Vertebrates 0 0 Signal transduction -1 chr19 53770016 53770918 WES head and neck squamous cell carcinoma VPRBP 9730 Vpr (HIV-1) binding protein 3p21.2 11674 30911 - "NP_055518;NP_001165375" "NM_014703;NM_001171904" - candidate 0 0 0 Eukaryotes 46 0 -1 38 chr3 51436203 51517844 WES chronic lymphocytic leukemia VRTN 55237 vertebrae development homolog (pig) 14q24.3 16593 20223 - NP_060698 NM_018228 ENSP00000256362 candidate 0 0 0 Vertebrates 0 0 DNA/RNA metabolism and transcription 23 chr14 74823487 74825592 WES colorectal VSTM2L 128434 V-set and transmembrane domain containing 2 like 20q11.23 12735 16096 - NP_542174 NM_080607 ENSP00000362560 candidate 0 0 0 Vertebrates 4 1 -1 -1 chr20 36531753 36572652 WGS lymphoma VTI1A 143187 vesicle transport through interaction with t-SNAREs homolog 1A (yeast) 10q25.2 18290 17792 614316 NP_660207 NM_145206 ENSP00000376792 known 1 0 0 Eukaryotes 11 0 Cellular processes -1 chr10 114207132 114575139 CGC colorectal VWA5B1 127731 von Willebrand factor A domain containing 5B1 1p36.12 8732 26538 - NP_001034589 "NM_144623;NM_001039500" ENSP00000364230 candidate 0 0 0 Last Universal Common Ancestor 0 0 -1 -1 chr1 20637095 20680753 WGS melanoma VWA7 80737 von Willebrand factor A domain containing 7 6p21.33 12880 13939 609693 NP_079534 NM_025258 ENSP00000364840 candidate 0 0 0 Eukaryotes 1 1 Cell response to stimuli 8 chr6 31733374 31744556 WES lymphoma VWF 7450 von Willebrand factor 12p13.3 1906 12726 613160 NP_000543 NM_000552 ENSP00000261405 candidate 0 0 0 Last Universal Common Ancestor 11 0 Cellular metabolism,Multicellular activities 76 chr12 6058184 6232362 WES,WGS pancreas,chronic lymphocytic leukemia WAS 7454 Wiskott-Aldrich syndrome (eczema-thrombocytopenia) Xp11.4-p11.21 2314 12731 300392 NP_000368 NM_000377 ENSP00000365891 known 0 1 0 Eukaryotes 35 0 Cellular metabolism,Cellular processes,Development,Immune system response,Multicellular activities 102 chrX 48542243 48549550 CGC WBP11 51729 WW domain binding protein 11 12p12.3 18293 16461 - NP_057396 NM_016312 ENSP00000261167 candidate 0 0 3 Eukaryotes 49 4 DNA/RNA metabolism and transcription,Regulation of transcription 98 chr12 14940002 14954317 WGS lung WDR24 84219 WD repeat domain 24 16p13.3 15665 20852 - NP_115635 NM_032259 ENSP00000293883 candidate 0 0 0 Last Universal Common Ancestor 4 0 -1 -1 chr16 734737 739640 WES chronic lymphocytic leukemia WDR37 22884 WD repeat domain 37 10p15.3 15668 31406 - NP_054742 NM_014023 ENSP00000263150 candidate 0 0 0 Last Universal Common Ancestor 5 5 -1 99 chr10 1118096 1175281 WGS glioblastoma WDR49 151790 WD repeat domain 49 3q26.1 8160 26587 - NP_849146 NM_178824 ENSP00000311343 candidate 0 0 0 Last Universal Common Ancestor 0 0 -1 -1 chr3 167196669 167322191 WGS melanoma WDR59 79726 WD repeat domain 59 16q23.1 13351 25706 - NP_085058 NM_030581 ENSP00000262144 candidate 0 0 0 Last Universal Common Ancestor 5 1 -1 69 chr16 74908110 75018915 WGS breast WDR72 256764 WD repeat domain 72 15q21.3 10987 26790 613214 NP_877435 NM_182758 ENSP00000379619 candidate 0 0 0 Eukaryotes 755 0 -1 -1 chr15 53809899 54025346 WGS lung WDR75 84128 WD repeat domain 75 2q32.2 7775 25725 - NP_115544 NM_032168 ENSP00000314193 candidate 0 0 0 Last Universal Common Ancestor 4 4 -1 -1 chr2 190306219 190340140 WES pancreas WDR91 29062 WD repeat domain 91 7q33 11035 24997 - NP_054868 NM_014149 ENSP00000346466 candidate 0 0 0 Eukaryotes 4 1 -1 32 chr7 134870906 134896254 WES breast WHSC1 7468 Wolf-Hirschhorn syndrome candidate 1 4p16.3 4259 12766 602952 "NP_579878;NP_579877;NP_579889;NP_579890;NP_001035889;NP_015627" "NM_133331;NM_133330;NM_133336;NM_133334;NM_014919;NM_133333;NM_133335;NM_133332;NM_001042424;NM_007331" "ENSP00000399251;ENSP00000372351;ENSP00000372348;ENSP00000381311;ENSP00000372347" known 1 0 0 Last Universal Common Ancestor 17 4 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription 95 chr4 1902382 1980633 CGC myeloma WHSC1L1 54904 Wolf-Hirschhorn syndrome candidate 1-like 1 8p11.2 6155 12767 607083 "NP_075447;NP_060248" "NM_023034;NM_017778" "ENSP00000313410;ENSP00000313983" known 1 0 0 Last Universal Common Ancestor 17 4 Cell cycle,Cellular metabolism,Cellular processes,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription 64 chr8 38133162 38205689 CGC,Amplified leukemia WIF1 11197 WNT inhibitory factor 1 12q14.3 5541 18081 605186 NP_009122 NM_007191 ENSP00000286574 known 1 0 0 Eukaryotes 5 1 Signal transduction 37 chr12 65445132 65514971 CGC salivary WIPF2 147179 WAS/WASL interacting protein family, member 2 17q21.2 18304 30923 609692 NP_573571 NM_133264 - candidate 0 0 0 Eukaryotes 23 0 -1 104 chr17 38416784 38433435 WES head and neck squamous cell carcinoma WNT1 7471 wingless-type MMTV integration site family, member 1 12q13 1276 12774 164820 NP_005421 NM_005430 - candidate 0 0 0 Metazoans 12 3 Cell motility and interactions,Development,Signal transduction 14 chr12 49372434 49375420 WGS melanoma WRAP53 55135 WD repeat containing, antisense to TP53 17p13.1 7670 25522 612661 "NP_060551;NP_001137462;NP_001137463;NP_001137464" "NM_018081;NM_001143990;NM_001143991;NM_001143992" "ENSP00000397219;ENSP00000411061;ENSP00000379727;ENSP00000434999" candidate 0 0 0 Last Universal Common Ancestor 8 3 -1 105 chr17 7591967 7606801 WGS prostate WRN 7486 Werner syndrome, RecQ helicase-like 8p12 5212 12791 604611 NP_000544 NM_000553 ENSP00000298139 known 0 1 0 Last Universal Common Ancestor 46 0 Cell cycle,Cell response to stimuli,Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism 24 chr8 30915964 31030615 CGC WT1 7490 Wilms tumor 1 11p13 6163 12796 607102 "NP_000369;NP_077744;NP_001185480;NP_077742;NP_001185481" "NM_000378;NM_024426;NM_001198551;NM_024424;NM_024425;NM_001198552" "ENSP00000415516;ENSP00000368370;ENSP00000435307;ENSP00000331327" known 0 1 0 Last Universal Common Ancestor 29 3 Cell cycle,Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription 16 chr11 32410607 32456888 CGC desmoplastic small round cell tumor,Wilms WWP1 11059 WW domain containing E3 ubiquitin protein ligase 1 8q21 3811 17004 602307 NP_008944 NM_007013 ENSP00000427793 candidate 0 0 1 Eukaryotes 18 0 Cell motility and interactions,Cellular metabolism,Cellular processes,DNA/RNA metabolism and transcription,Development,Other,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction 94 chr8 87386280 87479119 WGS liver WWTR1 25937 WW domain containing transcription regulator 1 3q23-q24 9580 24042 607392 "NP_001161752;NP_056287;NP_001161750" "NM_001168280;NM_015472;NM_001168278" ENSP00000419465 known 1 0 0 Eukaryotes 20 2 Cellular metabolism,DNA/RNA metabolism and transcription,Development,Regulation of intracellular processes and metabolism,Regulation of transcription 75 chr3 149238595 149375093 CGC,WGS epitheliod hemangioendothelioma,breast XDH 7498 xanthine dehydrogenase 2p23.1 6363 12805 607633 NP_000370 NM_000379 ENSP00000368727 candidate 0 0 0 Last Universal Common Ancestor 4 1 Development,Multicellular activities 75 chr2 31558827 31637532 WES breast XIRP1 165904 xin actin-binding repeat containing 1 3p22.2 16727 14301 609777 "NP_919269;NP_001185550" "NM_194293;NM_001198621" "ENSP00000379550;ENSP00000343140" candidate 0 0 0 Vertebrates 1 1 Cellular processes -1 chr3 39225408 39230936 WES breast XIRP2 129446 xin actin-binding repeat containing 2 2q24.3 10267 14303 609778 "NP_689594;NP_001186074;NP_001186073;NP_001186072;NP_001073278" "NM_152381;NM_001199145;NM_001199144;NM_001199143;NM_001079810" "ENSP00000386454;ENSP00000386619;ENSP00000387255;ENSP00000386981;ENSP00000386840" candidate 0 0 0 Vertebrates 8 1 Cellular processes -1 chr2 167759993 168110633 WES,WGS cholangiocarcinoma,melanoma XPA 7507 xeroderma pigmentosum, complementation group A 9q22.3 2045 12814 611153 NP_000371 "NR_027302;NM_000380" ENSP00000364270 known 0 1 0 Eukaryotes 31 3 Cellular metabolism,DNA/RNA metabolism and transcription 26 chr9 100437724 100459574 CGC XPC 7508 xeroderma pigmentosum, complementation group C 3p25 2046 12816 613208 "NP_001139241;NP_004619" "NR_027299;NM_001145769;NM_004628" ENSP00000285021 known 0 1 0 Eukaryotes 41 1 Cell cycle,Cell response to stimuli,Cellular metabolism,DNA/RNA metabolism and transcription,Signal transduction 96 chr3 14187444 14220068 CGC XPNPEP2 7512 X-prolyl aminopeptidase (aminopeptidase P) 2, membrane-bound Xq25 2144 12823 300145 NP_003390 NM_003399 ENSP00000360147 candidate 0 0 0 Last Universal Common Ancestor 0 0 Cellular metabolism 49 chrX 128873190 128902458 WES lung XPO1 7514 exportin 1 (CRM1 homolog, yeast) 2p15 3975 12825 602559 NP_003391 NM_003400 ENSP00000384863 known 1 0 0 Eukaryotes 150 6 Cell response to stimuli,Cellular processes,DNA/RNA metabolism and transcription 107 chr2 61705958 61761032 CGC,WES,WGS leukemia,chronic lymphocytic leukemia XPO7 23039 exportin 7 8p21 5846 14108 606140 NP_055839 "NM_015024;NM_001100162;NM_001100161" ENSP00000252512 candidate 0 0 0 Eukaryotes 14 7 Cellular processes,DNA/RNA metabolism and transcription 83 chr8 21824365 21862596 WES acute myeloid leukemia XRCC2 7516 X-ray repair complementing defective repair in Chinese hamster cells 2 7q36.1 2656 12829 600375 NP_005422 NM_005431 ENSP00000352271 candidate 0 0 0 Eukaryotes 3 4 Cell cycle,DNA/RNA metabolism and transcription 74 chr7 152345730 152357867 WGS liver XRN1 54464 5'-3' exoribonuclease 1 3q23 10470 30654 607994 "NP_061874;NP_001036069" "NM_019001;NM_001042604" ENSP00000264951 candidate 0 0 0 Eukaryotes 45 4 Cell cycle,Regulation of intracellular processes and metabolism -1 chr3 142030356 142166786 WGS lymphoma YAP1 10413 Yes-associated protein 1 11q13 9424 16262 606608 "NP_001181973;NP_006097;NP_001181974;NP_001123617" "NM_001195044;NM_006106;NM_001195045;NM_001130145" "ENSP00000282441;ENSP00000445635;ENSP00000331023" known 0 0 1 Eukaryotes 20 5 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription 26 chr11 101981580 102100668 CGC,Amplified YEATS4 8089 YEATS domain containing 4 12q13-q15 3666 24859 602116 NP_006521 NM_006530 ENSP00000247843 known 0 0 0 Last Universal Common Ancestor 32 0 Cell cycle,Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription 33 chr12 69753753 69784093 CGC,Amplified YWHAB 7529 tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide 20q13.1 3184 12849 601289 "NP_647539;NP_003395" "NM_139323;NM_003404" "ENSP00000361930;ENSP00000300161" known 0 0 13 Eukaryotes 321 0 Cell cycle,Cellular processes,Development,Regulation of intracellular processes and metabolism,Signal transduction 109 chr20 43530175 43535076 CGC,Amplified YWHAE 7531 tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide 17p13.3 5457 12851 605066 NP_006752 "NM_006761;NR_024058" ENSP00000264335 known 1 0 5 Eukaryotes 120 1 Signal transduction 105 chr17 1248744 1303404 CGC sarcoma YWHAQ 10971 tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide 2p25.1 886 12854 609009 NP_006817 NM_006826 ENSP00000238081 known 0 0 10 Eukaryotes 104 3 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription 109 chr2 9725418 9770581 CGC,Amplified YWHAZ 7534 tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide 8q23.1 3183 12855 601288 "NP_003397;NP_001129173;NP_001129171;NP_001129174;NP_663723;NP_001129172" "NM_003406;NM_001135701;NM_001135699;NM_001135702;NM_145690;NM_001135700" "ENSP00000398599;ENSP00000379286;ENSP00000309503;ENSP00000379288" known 0 0 15 Eukaryotes 707 5 Cell cycle,Development,Regulation of intracellular processes and metabolism,Signal transduction 109 chr8 101932924 101961117 CGC,Amplified ZAN 7455 zonadhesin 7q22 3846 12857 602372 "NP_775082;NP_003377" "NM_173059;NM_173057;NM_173058;NM_173056;NM_003386;NM_173055" "ENSP00000422387;ENSP00000423579" candidate 0 0 0 Last Universal Common Ancestor 0 0 Cell motility and interactions,Development -1 chr7 100331792 100395244 WES pancreas ZBTB16 7704 zinc finger and BTB domain containing 16 11q23.1 11762 12930 176797 "NP_001018011;NP_005997" "NM_001018011;NM_006006" "ENSP00000376721;ENSP00000338157" known 1 0 0 Last Universal Common Ancestor 163 0 Cell cycle,Cellular metabolism,DNA/RNA metabolism and transcription,Development,Regulation of intracellular processes and metabolism,Regulation of transcription 86 chr11 113934023 114121274 CGC leukemia ZBTB41 360023 zinc finger and BTB domain containing 41 1q31.3 17017 24819 - NP_919290 NM_194314 - candidate 0 0 0 Last Universal Common Ancestor 2 2 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription -1 chr1 197128492 197169603 WGS melanoma ZC3H11A 9877 zinc finger CCCH-type containing 11A 1q32.1 11100 29093 613513 NP_055642 NM_014827 ENSP00000333253 candidate 0 0 2 Eukaryotes 26 6 -1 109 chr1 203786199 203821524 WGS lung ZDBF2 57683 zinc finger, DBF-type containing 2 2q33.3 - 29313 - NP_065974 NM_020923 ENSP00000363545 candidate 0 0 0 Vertebrates 1 0 -1 -1 chr2 207146574 207176314 WES lung ZFHX3 463 zinc finger homeobox 3 16q22.3 75 777 104155 "NP_001158238;NP_008816" "NM_001164766;NM_006885" "ENSP00000438926;ENSP00000268489" candidate 0 0 0 Eukaryotes 10 6 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription 9 chr16 72821066 72994044 WES bladder,prostate ZFHX4 79776 zinc finger homeobox 4 8q21.11 9503 30939 606940 NP_078997 NM_024721 ENSP00000430497 candidate 0 0 0 Eukaryotes 1 0 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription 58 chr8 77616324 77776798 WES head and neck squamous cell carcinoma ZFP36L1 677 zinc finger protein 36, C3H type-like 1 14q22-q24 3041 1107 601064 "NP_004917;NP_001231627;NP_001231630" "NM_004926;NM_001244698;NM_001244701" ENSP00000388402 candidate 0 0 0 Eukaryotes 3 4 Cellular metabolism,DNA/RNA metabolism and transcription,Development,Regulation of intracellular processes and metabolism,Regulation of transcription 106 chr14 69256253 69262866 WES breast ZFP64 55734 zinc finger protein 64 homolog (mouse) 20q13.2 15728 15940 - "NP_060667;NP_955459;NP_955458;NP_071371" "NM_018197;NM_199427;NM_199426;NM_022088" "ENSP00000216923;ENSP00000344615;ENSP00000360570;ENSP00000355179" candidate 0 0 0 Last Universal Common Ancestor 18 0 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription 78 chr20 50768688 50808175 WES breast ZFYVE26 23503 zinc finger, FYVE domain containing 26 14q24.1 15734 20761 612012 NP_056161 NM_015346 ENSP00000251119 candidate 0 0 0 Eukaryotes 0 4 -1 61 chr14 68215156 68282680 WES,WGS breast,glioblastoma ZHX2 22882 zinc fingers and homeoboxes 2 8q24.13 16458 18513 609185 NP_055758 NM_014943 ENSP00000314709 candidate 0 0 0 Metazoans 16 0 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription 63 chr8 123963751 123966261 WES neuroblastoma ZIC3 7547 Zic family member 3 Xq26.2 2225 12874 300265 NP_003404 NM_003413 ENSP00000287538 candidate 0 0 0 Last Universal Common Ancestor 1 1 Cellular metabolism,DNA/RNA metabolism and transcription,Development,Regulation of intracellular processes and metabolism,Regulation of transcription 17 chrX 136648851 136652226 WGS liver ZIM2 23619 zinc finger, imprinted 2 19q13.4 10321 12875 - "NP_001139799;NP_001139798;NP_056178" "NM_001146327;NM_001146326;NM_015363" "ENSP00000470326;ENSP00000375589;ENSP00000221722" candidate 0 0 -1 Last Universal Common Ancestor 0 0 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription 18 - 0 0 WES pancreas ZMYM2 7750 zinc finger, MYM-type 2 13q11-q12 3745 12989 602221 "NP_003444;NP_001177894;NP_932072;NP_001177893" "NM_003453;NM_001190965;NM_197968;NM_001190964" "ENSP00000413744;ENSP00000372322" known 1 0 0 Metazoans 39 3 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription 89 chr13 20567213 20660151 CGC,HTMS myeloma,non-hodgkin lymphoma,breast,lung,ovarian,pancreas,prostate ZMYM3 9203 zinc finger, MYM-type 3 Xq13.1 2088 13054 300061 "NP_963893;NP_001164633;NP_005087;NP_001164634" "NM_201599;NM_001171162;NM_005096;NM_001171163" "ENSP00000363110;ENSP00000363093;ENSP00000343909;ENSP00000322845" candidate 0 0 0 Metazoans 4 0 -1 94 chrX 70460769 70473105 WGS medulloblastoma ZMYM4 9202 zinc finger, MYM-type 4 1p32-p34 10326 13055 613568 NP_005086 NM_005095 ENSP00000322915 candidate 0 0 0 Metazoans 8 0 -1 89 chr1 35790961 35885275 WES colorectal ZMYND10 51364 zinc finger, MYND-type containing 10 3p21.3 6145 19412 607070 NP_056980 NM_015896 ENSP00000353289 candidate 0 0 0 Eukaryotes 5 0 -1 54 chr3 50378844 50383010 HTMS lung ZNF217 7764 zinc finger protein 217 20q13.2 4272 13009 602967 NP_006517 NM_006526 ENSP00000304308 known 0 0 0 Eukaryotes 10 9 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription 47 chr20 52188286 52199365 CGC,WGS,Amplified melanoma ZNF226 7769 zinc finger protein 226 19q13.2 15751 13019 - "NP_057003;NP_001027544;NP_001139692;NP_001027545;NP_001027546" "NM_015919;NM_016444;NM_001032372;NM_001146220;NM_001032375;NM_001032373;NM_001032374" "ENSP00000393265;ENSP00000336719;ENSP00000300823" candidate 0 0 0 Last Universal Common Ancestor 4 3 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription 49 chr19 44676241 44679183 WGS liver ZNF280C 55609 zinc finger protein 280C Xq26.1 6526 25955 - NP_060136 NM_017666 ENSP00000360017 candidate 0 0 0 Eukaryotes 2 2 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription -1 chrX 129339272 129380977 WGS melanoma ZNF319 57567 zinc finger protein 319 16q21 18326 13644 - NP_065858 NM_020807 ENSP00000299237 candidate 0 0 0 Last Universal Common Ancestor 1 0 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription -1 chr16 58030424 58032169 WGS lymphoma ZNF331 55422 zinc finger protein 331 19q13.42 5827 15489 606043 "NP_001240729;NP_001240730;NP_001240727;NP_001073376;NP_001240728;NP_061025;NP_001073375" "NM_001253800;NM_001253801;NM_001253798;NM_001079907;NM_001253799;NM_018555;NM_001079906" ENSP00000253144 known 1 0 0 Last Universal Common Ancestor 14 0 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription 98 chr19 54079950 54081203 CGC thyroid ZNF37A 7587 zinc finger protein 37A 10p11.2 18508 13102 - "NP_001171572;NP_001007095;NP_003412" "NM_001178101;NM_001007094;NM_003421" "ENSP00000329141;ENSP00000354377" candidate 0 0 0 Last Universal Common Ancestor 0 1 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription 9 chr10 38403680 38407762 WGS chronic lymphocytic leukemia ZNF384 171017 zinc finger protein 384 12p12 18332 11955 609951 "NP_001129206;NP_597733;NP_001035009" "NM_001135734;NM_001039918;NM_133476;NM_001039917;NM_001039920;NM_001039919;NM_001039916" "ENSP00000348018;ENSP00000380019;ENSP00000380013" known 1 0 0 Last Universal Common Ancestor 8 5 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription 80 chr12 6776883 6788686 CGC leukemia ZNF391 346157 zinc finger protein 391 6p22.1 18461 18779 - NP_001070249 "NM_001076781;NM_001013719" - candidate 0 0 0 Last Universal Common Ancestor 0 0 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription 31 chr6 27368150 27369223 WES pancreas ZNF407 55628 zinc finger protein 407 18q23 11713 19904 - "NP_001139662;NP_001139661;NP_060227" "NM_001146190;NM_001146189;NM_017757" "ENSP00000463270;ENSP00000310359;ENSP00000299687" candidate 0 0 0 Last Universal Common Ancestor 7 3 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription 10 chr18 72342976 72776421 WGS prostate ZNF442 79973 zinc finger protein 442 19p13.2 15795 20877 - NP_110451 NM_030824 ENSP00000242804 candidate 0 0 4 Last Universal Common Ancestor 1 1 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription 9 chr19 12460518 12463928 WES colorectal ZNF497 162968 zinc finger protein 497 19q13.43 15806 23714 - "NP_001193938;NP_940860" "NM_001207009;NM_198458" ENSP00000311183 candidate 0 0 0 Last Universal Common Ancestor 0 0 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription -1 chr19 58867508 58869001 WES glioblastoma ZNF518A 9849 zinc finger protein 518A 10q24.1 18349 29009 - NP_055618 NM_014803 - candidate 0 0 0 Eukaryotes 2 1 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription 61 chr10 97916080 97920527 WGS chronic lymphocytic leukemia,glioblastoma ZNF521 25925 zinc finger protein 521 18q11.2 18350 24605 610974 NP_056276 NM_015461 ENSP00000354794 known 1 0 0 Last Universal Common Ancestor 0 2 -1 -1 chr18 22669429 22930910 CGC,WES leukemia,colorectal,lung,lymphoma ZNF536 9745 zinc finger protein 536 19q12 15825 29025 - NP_055532 NM_014717 ENSP00000347730 candidate 0 0 0 Eukaryotes 1 0 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription 63 chr19 30934470 31040426 WES lung ZNF559 84527 zinc finger protein 559 19p13.2 18352 28197 - "NP_001189340;NP_001189336;NP_115886;NP_001189335;NP_001189337;NP_001189339;NP_001189338;NP_001189341" "NM_001202411;NM_001202407;NM_032497;NM_001202406;NM_001202408;NM_001202410;NM_001202409;NM_001202412" "ENSP00000325393;ENSP00000468153" candidate 0 0 0 Last Universal Common Ancestor 4 2 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription -1 chr19 9449869 9453741 WGS lung ZNF560 147741 zinc finger protein 560 19p13.2 15842 26484 - NP_689689 NM_152476 ENSP00000301480 candidate 0 0 0 Last Universal Common Ancestor 1 0 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription -1 chr19 9577253 9585001 WGS liver ZNF569 148266 zinc finger protein 569 19q13.12 15849 24737 613904 NP_689697 NM_152484 ENSP00000325018 candidate 0 0 0 Last Universal Common Ancestor 2 0 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription -1 chr19 37903502 37905322 WES breast ZNF572 137209 zinc finger protein 572 8q24.13 15851 26758 - NP_689625 NM_152412 ENSP00000319305 candidate 0 0 0 Last Universal Common Ancestor 0 1 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription -1 chr8 125988589 125990097 WES head and neck squamous cell carcinoma ZNF595 152687 zinc finger protein 595 4p16.3 15868 27196 - NP_872330 NM_182524 - candidate 0 0 2 Eukaryotes 2 0 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription -1 chr4 85621 87314 WES prostate ZNF638 27332 zinc finger protein 638 2p13.1 11736 17894 614349 "NP_001014972;NP_001239541;NP_001239542;NP_055312" "NM_001014972;NM_001252612;NM_001252613;NM_014497" "ENSP00000386433;ENSP00000264447" candidate 0 0 0 Metazoans 38 3 DNA/RNA metabolism and transcription,Regulation of transcription 103 chr2 71576085 71661934 WES pancreas ZNF639 51193 zinc finger protein 639 3q26.33 15882 30950 - NP_057415 NM_016331 ENSP00000325634 known 0 0 0 Eukaryotes 6 0 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription 14 chr3 179046082 179052207 CGC,Amplified ZNF646 9726 zinc finger protein 646 16p11.2 15886 29004 - NP_055514 NM_014699 ENSP00000300850 candidate 0 0 0 Eukaryotes 9 0 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription 36 chr16 31087646 31094410 WES,WGS breast,prostate ZNF668 79759 zinc finger protein 668 16p11.2 7828 25821 - "NP_001166139;NP_001166140;NP_078982;NP_001166141" "NM_001172668;NM_001172669;NM_024706;NM_001172670" "ENSP00000440149;ENSP00000442573;ENSP00000441349;ENSP00000300849" candidate 0 0 0 Last Universal Common Ancestor 4 0 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription 0 chr16 31072392 31075939 WES breast ZNF687 57592 zinc finger protein 687 1q21.3 13859 29277 610568 NP_065883 NM_020832 ENSP00000336620 candidate 0 0 0 Eukaryotes 11 0 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription -1 chr1 151258768 151263682 WES glioblastoma ZNF69 7620 zinc finger protein 69 19p13.2 11836 13138 194543 NP_068734 NM_021915 ENSP00000345333 candidate 0 0 3 Last Universal Common Ancestor 0 0 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription -1 chr19 11998739 12015701 WGS lung ZNF773 374928 zinc finger protein 773 19q13.43 14655 30487 - NP_940944 NM_198542 ENSP00000282292 candidate 0 0 1 Last Universal Common Ancestor 3 0 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription -1 chr19 58016025 58018789 WGS lung ZNF786 136051 zinc finger protein 786 7q36.1 13232 21806 - NP_689624 NM_152411 ENSP00000417470 candidate 0 0 0 Last Universal Common Ancestor 0 0 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription -1 chr7 148767518 148777809 WGS breast ZNF799 90576 zinc finger protein 799 19p13.2 - 28071 - NP_001074290 "NM_203381;NM_001080821" ENSP00000411084 candidate 0 0 3 Last Universal Common Ancestor 1 2 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription -1 chr19 12501283 12504237 WGS breast ZNF804A 91752 zinc finger protein 804A 2q32.1 12804 21711 612282 NP_919226 NM_194250 ENSP00000303252 candidate 0 0 0 Vertebrates 3 1 -1 25 chr2 185463687 185803750 WES kidney ZNF804B 219578 zinc finger protein 804B 7q21.13 8721 21958 - NP_857597 NM_181646 ENSP00000329638 candidate 0 0 0 Eukaryotes 0 1 -1 -1 chr7 88389291 88966343 WES head and neck squamous cell carcinoma ZNF823 55552 zinc finger protein 823 19p13.2 - 30936 - NP_001073962 NM_001080493 ENSP00000340683 candidate 0 0 6 Last Universal Common Ancestor 4 2 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription -1 chr19 11832519 11836142 WES head and neck squamous cell carcinoma ZNF830 91603 zinc finger protein 830 17q12 14469 28291 - NP_443089 NM_052857 ENSP00000354518 candidate 0 0 0 Eukaryotes 14 0 Cell cycle,Development -1 chr17 33288586 33289701 WES lymphoma ZNF831 128611 zinc finger protein 831 20q13.32 - 16167 - NP_848552 NM_178457 ENSP00000360069 candidate 0 0 0 Eukaryotes 0 0 -1 -1 chr20 57766075 57829795 WES melanoma ZRSR2 8233 zinc finger (CCCH type), RNA-binding motif and serine/arginine rich 2 Xp22.1 2068 23019 300028 NP_005080 NM_005089 ENSP00000303015 known 0 1 2 Eukaryotes 5 0 DNA/RNA metabolism and transcription,Regulation of transcription 97 chrX 15808619 15841362 CGC,WES,WGS leukemia,myelodysplasia,breast ZSWIM3 140831 zinc finger, SWIM-type containing 3 20q13.12 15903 16157 - NP_542790 "NR_037628;NM_080752" ENSP00000255152 candidate 0 0 0 Eukaryotes 1 2 -1 -1 chr20 44486465 44507285 WES gastric ZWILCH 55055 Zwilch, kinetochore associated, homolog (Drosophila) 15q22.31 7640 25468 609984 NP_060445 "NM_017975;NR_003105" ENSP00000311429 candidate 0 0 0 Eukaryotes 6 0 Cell cycle 7 chr15 66797677 66839014 WES lymphoma ZZEF1 23140 zinc finger, ZZ-type with EF-hand domain 1 17p13.2 15906 29027 - NP_055928 NM_015113 ENSP00000371051 candidate 0 0 0 Eukaryotes 7 0 Cell cycle 86 chr17 3910187 4046189 WES gastric